format-version: 1.2
data-version: releases/2024-03-16
subsetdef: 1_STAR ""
subsetdef: 2_STAR ""
subsetdef: 3_STAR ""
subsetdef: abnormal_slim ""
subsetdef: absent_slim ""
subsetdef: added_for_HCA ""
subsetdef: AISM:0000171 ""
subsetdef: attribute_slim ""
subsetdef: blood_and_immune_upper_slim ""
subsetdef: cell_quality ""
subsetdef: cellxgene_subset ""
subsetdef: common_anatomy ""
subsetdef: cumbo ""
subsetdef: developmental_classification ""
subsetdef: disposition_slim ""
subsetdef: early_development ""
subsetdef: efo_slim ""
subsetdef: emapa_ehdaa2 ""
subsetdef: eye_upper_slim ""
subsetdef: functional_classification ""
subsetdef: general_cell_types_upper_slim ""
subsetdef: gocheck_do_not_annotate ""
subsetdef: gocheck_do_not_manually_annotate ""
subsetdef: goslim_agr ""
subsetdef: goslim_candida ""
subsetdef: goslim_chembl ""
subsetdef: goslim_drosophila ""
subsetdef: goslim_flybase_ribbon ""
subsetdef: goslim_generic ""
subsetdef: goslim_metagenomics ""
subsetdef: goslim_mouse ""
subsetdef: goslim_pir ""
subsetdef: goslim_plant ""
subsetdef: goslim_pombe ""
subsetdef: goslim_prokaryote ""
subsetdef: goslim_synapse ""
subsetdef: goslim_yeast ""
subsetdef: grouping_class ""
subsetdef: homology_grouping ""
subsetdef: hpo_slim ""
subsetdef: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension ""
subsetdef: http://purl.obolibrary.org/obo/valid_for_go_gp2term ""
subsetdef: http://purl.obolibrary.org/obo/valid_for_go_ontology ""
subsetdef: http://purl.obolibrary.org/obo/valid_for_gocam ""
subsetdef: human_reference_atlas ""
subsetdef: inconsistent_with_fma ""
subsetdef: kidney_upper_slim ""
subsetdef: location_grouping ""
subsetdef: major_organ ""
subsetdef: mpath_slim ""
subsetdef: non_informative ""
subsetdef: organ_slim ""
subsetdef: pheno_slim ""
subsetdef: phenotype_rcn ""
subsetdef: relational_slim ""
subsetdef: ro-eco ""
subsetdef: RO:0002259 ""
subsetdef: scalar_slim ""
subsetdef: uberon_slim ""
subsetdef: ubprop:upper_level ""
subsetdef: unverified_taxonomic_grouping ""
subsetdef: upper_level ""
subsetdef: value_slim ""
subsetdef: vertebrate_core ""
synonymtypedef: blast_name ""
synonymtypedef: DEPRECATED ""
synonymtypedef: equivalent_name ""
synonymtypedef: genbank_common_name ""
synonymtypedef: Gene-based ""
synonymtypedef: human ""
synonymtypedef: HUMAN_PREFERRED ""
synonymtypedef: in_part ""
synonymtypedef: INCONSISTENT ""
synonymtypedef: INN ""
synonymtypedef: IUPAC_NAME ""
synonymtypedef: OMO:0003000 ""
synonymtypedef: OMO:0003002 ""
synonymtypedef: OMO:0003003 ""
synonymtypedef: OMO:0003004 ""
synonymtypedef: OMO:0003011 ""
synonymtypedef: PENDING_REVIEW ""
synonymtypedef: PRO-short-label ""
synonymtypedef: scientific_name ""
synonymtypedef: SENSU ""
synonymtypedef: syngo_official_label ""
synonymtypedef: synonym ""
synonymtypedef: systematic_synonym ""
synonymtypedef: vertebrate ""
ontology: aism
property_value: dc-description "The ontology for the Anatomy of the Insect SkeletoMuscular system (AISM) contains terms used to describe the cuticle - as a single anatomical structure - and the skeletal muscle system, to be used in insect biodiversity research." xsd:string
property_value: dc-title "Ontology for the Anatomy of the Insect SkeletoMuscular system" xsd:string
property_value: dcterms-license https://creativecommons.org/licenses/by/4.0/
property_value: has_ontology_root_term "http://purl.obolibrary.org/obo/AISM_0000174" xsd:string
property_value: has_ontology_root_term "http://purl.obolibrary.org/obo/PATO_0000001" xsd:string
property_value: has_ontology_root_term "http://purl.obolibrary.org/obo/UBERON_0001062" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor "Giulio Montanaro (gmontanaro) https://orcid.org/0000-0003-0836-1364" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor "István Mikó (imiko) https://orcid.org/0000-0003-2938-9075" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor "Jennifer C. Girón (jgiron) https://orcid.org/0000-0002-0851-6883" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor "Luis A. González Montaña (lagonzalezmo) https://orcid.org/0000-0002-9136-9932" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor "Sergei Tarasov (starasov) https://orcid.org/0000-0001-5237-2330" xsd:string
property_value: owl:versionInfo "2024-03-16" xsd:string

[Term]
id: AISM:0000000
name: cuticular internal depression
def: "The projection of the inner surface of the cuticle." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-05-19"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
relationship: has_characteristic PATO:0001857 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! concave
relationship: part_of BSPO:0000061 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! proximal side

[Term]
id: AISM:0000001
name: resilin {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"}
def: "Resilin is an elastomeric protein found in many insects and other arthropods. It provides soft rubber-elasticity to mechanically active organs and tissue.\nhttps://en.wikipedia.org/wiki/Resilin" [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"}
is_a: PR:000000001 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! protein
property_value: curator_notes "This is a generalized term to refer to this protein as the only option available now is pro-resilin (fruit fly) [http://purl.obolibrary.org/obo/PR_Q9V7U0]" xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"}

[Term]
id: AISM:0000002
name: insect articulation
def: "The region of cuticle that is composed two articular surfaces that are adjacent to each other." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
property_value: curator_notes "Articulations are 'anatomical clusters', collections of not direclty connected (continuous) sclerite surfaces that are adjacent to another sclerite. The cranio-mandibular articulation is the articular surface of the cranium and the adjacent articular surface of the mandible. The articular surfaces are sometimes located on the same sclerite." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}

[Term]
id: AISM:0000003
name: insect sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sclerite: distinctly sclerotized region of the integument, with thick layer of exocuticle.\"", IAO:0000232="Modified 2023-01-09: specifying insect sclerite.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The region of the insect cuticle that is less flexible than the neighboring conjunctiva(e) (conjunctiva(e) that the sclerite is continuous with." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
xref: http://flybase.org/cgi-bin/fbcvq.html?query=FBbt\:00004475 "sclerite"
xref: http://purl.obolibrary.org/obo/HAO_0000909 "sclerite" {def="The area of the cuticle that is less flexible than adjacent conjunctivae."}
xref: http://purl.obolibrary.org/obo/UBERON_6004475 "insect sclerite"
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
property_value: IAO:0000118 "esclerito" xsd:string {creation_date="2023-01-09"}

[Term]
id: AISM:0000004
name: conjunctiva
def: "The region of the insect cuticle that is more flexible than the neighboring sclerite(s) [sclerite(s) that the conjunctiva is continuous with]." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
synonym: "membrane" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Membrane: very flexible, unsclerotized area of the integument.\""}
xref: http://purl.obolibrary.org/obo/HAO_0000221 "conjunctiva" {def="The area of the cuticle that is more flexible than adjacent sclerites."}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
relationship: continuous_with AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
property_value: curator_notes "Conjunctivae are more flexible and usually less thick than sclerties of the cuticle allowing the sclerites to move relative to each other.\nMicro-CT based methods cannot be used to accurately differentiate slcerites from conjunctiuvae. CLSM (the excitation wavelengths of sclerites and conjunctivae are different in response of 488 nm emission vawelength), histological sections or simple dissections need to be applied to define relative flexibility of the insect cuticle.\n\nIf a conjunctiva entirelly encircles a sclerite, then the 'encircles' and 'encircled by' object properties are used to link the sclerite and the conjunctiva even in cases in which the encircled sclerites or conjunctivae are part of an evagination allowing to model spatial relationship between appendage segments: the pedicel is encircled by the scapal-pedicellar conjunctiva, which is encircled by the scape or the the coxa encircles the coxo-femoral conjunctiuva that encircels the femur." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}

[Term]
id: AISM:0000005
name: cuticular depression
def: "The region of the cuticle that corresponds to a concave surface." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
is_a: BFO:0000004 ! independent continuant
relationship: has_characteristic PATO:0001857 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! concave
relationship: in_distal_side_of AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
property_value: curator_notes "External cuticular depression. The surface of the cuticle in insects is the entire surface of an organism, and it is composed of flat, concave and convex regions. Concavities sometimes correspons with invaginations of the cuticle and the underlaying sinlge layer epidermis, somtimes correspond to a decreased cuticular thickness." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}

[Term]
id: AISM:0000006
name: cuticular invagination
def: "The region of cuticle that corresponds with an invagination of the single layer epidermis (epidermal fold). The cuticular invagination sometimes corresponds to a cuticular depression (concavity on the surface of the cuticle)." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
relationship: RO:0002008 AISM:0000000 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular internal depression
relationship: RO:0002008 AISM:0000005 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular depression

[Term]
id: AISM:0000007
name: elastic cuticle {creation_date="2020-10-27"}
def: "The region of cuticle with higher content of resilin." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
is_a: PR:000050567 ! protein-containing material entity
relationship: composed_primarily_of AISM:0000001 {IAO:0000232="Modified 2024-02-14: updated to 'composed primarily of' and linked to resilin\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! resilin

[Term]
id: AISM:0000008
name: cuticular protrusion
def: "The region of the cuticle that corresponds to a convex surface." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
relationship: has_characteristic PATO:0001355 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! convex
relationship: part_of BSPO:0000062 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! distal side
property_value: curator_notes "The surface of the cuticle in insects is the entire surface of an organism, and it is composed of flat, concave and convex regions. Convexities sometimes correspons with evaginations of the cuticle and the underlaying sinlge layer epidermis and sometimes correspond to an increased cuticular thickness.\"" xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}

[Term]
id: AISM:0000009
name: cuticular fossa {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"}
def: "The cuticular depression that is adjacent to a cuticular condyle." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"}
is_a: AISM:0000005 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! cuticular depression
relationship: adjacent_to AISM:0000010 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! cuticular condyle

[Term]
id: AISM:0000010
name: cuticular condyle {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"}
def: "The cuticular protrusion that is part of an insect sclerite and adjacent to an articular surface." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! cuticular protrusion
relationship: adjacent_to AISM:0000167 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! articular surface
relationship: part_of AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! insect sclerite

[Term]
id: AISM:0000013
name: evaginated {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
def: "A part or structure that is produced by evagination." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: PATO:0001355 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! convex

[Term]
id: AISM:0000014
name: insect cranio-mandibular articulation {IAO:0000232="Modified 2023-02-05: specified insect.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The articulation between the mandible and the cranium." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
is_a: AISM:0000002 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation

[Term]
id: AISM:0000015
name: cranio-cardinal articulation
def: "The articulation between the cardo and the cranium." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
is_a: AISM:0000002 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation

[Term]
id: AISM:0000016
name: cranio-antennal articulation
def: "The articulation between the scapus and the cranium." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
is_a: AISM:0000002 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation

[Term]
id: AISM:0000017
name: insect head-cervical articulation {IAO:0000232="Modified 2023-02-05: specified insect.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The articulation between the head and the neck." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
is_a: AISM:0000002 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation

[Term]
id: AISM:0000018
name: cardo {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cardo: basal element of maxilla, articulating with head capsule; usually moved by one cranial muscle and one tentorial muscle.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The sclerite of the insect maxilla that is attached to the head capsule by the oral foraminal conjunctiva and to the cuticle of stipes by the stipito-cardinal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: adjacent_to AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule
relationship: adjacent_to AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! stipes
relationship: continuous_with AISM:0000099 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! oral foraminal conjunctiva
relationship: continuous_with AISM:0000110 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cardo-stipital conjunctiva
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla
property_value: IAO:0000589 "cuticle of cardo" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000019
name: head capsule {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The head capsule is almost always a rigid, well sclerotized structural unit, equipped with a defined set of appendages. It is reinforced by strengthening ridges and the endoskeletal tentorium\""}
def: "The sclerite of the insect head that is attached to the neck membrane and the oral foraminal conjunctiva, bears the eye cuticle and surrounds the brain" [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
synonym: "cephalic capsule" EXACT [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "insect cranium" EXACT [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: AISM:0000078 AISM:0000099 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles oral foraminal conjunctiva
relationship: continuous_with AISM:0000098 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! neck membrane
relationship: has_part AISM:0000088 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! eye cuticle
relationship: part_of AISM:0000107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head
relationship: surrounds UBERON:0000955 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! brain

[Term]
id: AISM:0000020
name: dorsal second axillary sclerite
def: "The axillary sclerite that is on the dorsal region of the basal wing conjunctiva and lateral to the first axillary sclerite." [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004161 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite
relationship: AISM:0000011 AISM:0000022 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! lateral_to first axillary sclerite

[Term]
id: AISM:0000021
name: abdominal tergite I
def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the tergum by the metanoto-abdominal tergite I conjunctiva." [] {IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite
relationship: anteriorly_connected_to AISM:0004082 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanoto-abdominal tergite I conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0000022
name: first axillary sclerite
def: "The axillary sclerite that is part of the dorsal region of the basal wing conjunctiva and is anterior to the third axillary sclerite." [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004161 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite
relationship: anterior_to AISM:0004223 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! third axillary sclerite

[Term]
id: AISM:0000023
name: galea {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Galea: outer endite lobe of maxilla, usually semimembranous and equipped with sensilla (mainly chemoreceptors).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the insect maxilla that is attached to the stipes by the stipito-galeal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage
relationship: adjacent_to AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes
relationship: continuous_with AISM:0004011 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-galeal conjunctiva
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla
property_value: IAO:0000589 "cuticle of galea" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000024
name: labial palpus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Labial palp: tactile appendage of the labium.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the paired appendage of the labium that is attached to the palpiger by the palpigero-palpal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage
relationship: adjacent_to AISM:0004006 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpiger
relationship: AISM:0000079 AISM:0004017 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by palpigero-palpal conjunctiva
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium
property_value: IAO:0000589 "cuticle of labial palpus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000026
name: lacinia {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Lacinia: inner endite lobe of maxilla, usually firmly connected or fused with stipes; usually sclerotized, with mesally curved apex and articulated spines arranged along mesal edge.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the insect maxilla that is attached to the cuticle of stipes by the stipito-lacinial conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage
relationship: adjacent_to AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes
relationship: continuous_with AISM:0004009 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-lacinial conjunctiva
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect maxilla
property_value: IAO:0000589 "cuticle of lacinia" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000027
name: cuticular evagination
def: "The region of cuticle that corresponds with an evagination of the cuticle and the single layer epidermis (epidermal fold). The cuticular evagination usually corresponds to a cuticular protrusion (convexity on the surface of the cuticle)." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular protrusion
intersection_of: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! cuticular protrusion
intersection_of: has_characteristic AISM:0000013 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! evaginated
intersection_of: RO:0002008 UBERON:0005157 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! coincident with epithelial fold
relationship: has_characteristic AISM:0000013 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! evaginated
relationship: RO:0002008 UBERON:0005157 {creation_date="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial fold

[Term]
id: AISM:0000028
name: solid cuticular protrusion {creation_date="2020-11-11"}
def: "The cuticular protrusion that does not correspond to an evagination." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular protrusion

[Term]
id: AISM:0000029
name: insect appendage {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"any part, piece, or organ attached by a joint to the body or to any other main structure\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The evagination of the cuticle that is musculated (connected to the body via muscles)." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000128 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multicellular cuticular evagination
intersection_of: AISM:0000128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! multicellular cuticular evagination
intersection_of: continuous_with UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! somatic muscle
relationship: continuous_with UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! somatic muscle
property_value: IAO:0000589 "cuticle of insect appendage" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000031
name: insect leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the paired appendage of the insect thorax that is composed of coxa, trochanter, femur, tibia, tarsus, and pretarsus." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: has_part AISM:0000047 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus
relationship: has_part AISM:0000075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia
relationship: has_part AISM:0000076 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur
relationship: has_part AISM:0000077 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa
relationship: has_part AISM:0004168 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter
relationship: has_part AISM:0004169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax
property_value: IAO:0000589 "cuticle of insect leg" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000032
name: antenna {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Antenna: head appendage of segment 2, innervated by deutocerebrum; in Insecta composed of scapus, pedicellus and flagellum; primarily multisegmented and filiform.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the head capsule that is connected by the  antenniferal-scapal conjunctiva to the cuticle of the scapus, which is connected by the scapal-pedicellar conjunctiva to the cuticle of the pedicellus; the cuticle of the pedicellus is connected by the pedicellar-first flagellomeral conjunctiva to the cuticle of the first flagellomere; the cuticle of the first flagellomere is connected by interflagellomeral conjunctiva to the next cuticle of flagellomere. Further cuticle of flagellomeres are connected to each other by interflagellomeral conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage
relationship: AISM:0000079 AISM:0004007 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by antenniferal-scapal conjunctiva
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: has_part AISM:0000113 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! scapus
relationship: has_part AISM:0000114 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! scapal-pedicellar conjunctiva
relationship: has_part AISM:0000115 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pedicellus
relationship: has_part AISM:0000117 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! flagellomere 1
relationship: has_part AISM:0000118 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pedicellar-first flagellomeral conjunctiva
relationship: has_part AISM:0004008 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! interflagellomeral conjunctiva
relationship: part_of UBERON:6003007 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect adult head
property_value: IAO:0000589 "cuticle of antenna" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000033
name: insect wing {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"in adult insects or subimago of Ephemeroptera, paired mambranous appendages, supported by veins, located on the mesothorax or metathorax, functioning in flight\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the flat, paired appendage on the dorso-lateral region of the pterothorax." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage
relationship: has_characteristic PATO:0000407 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! flat
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
property_value: IAO:0000589 "cuticle of insect wing" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000034
name: fore leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the paired appendage of the prothorax that is anterior to the cuticle of a mid leg and composed of cuticle of procoxa, cuticle of protrochanter, cuticle of profemur, cuticle of protibia, cuticle of protarsus, and cuticle of propretarsus." [] {creation_date="2021-04-03", http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg
relationship: anterior_to AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg
relationship: has_part AISM:0000066 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! procoxa
relationship: has_part AISM:0000067 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! protibia
relationship: has_part AISM:0000070 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! profemur
relationship: has_part AISM:0004171 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! protrochanter
relationship: has_part AISM:0004190 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! protarsus
relationship: has_part AISM:0004194 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! propretarsus
relationship: part_of AISM:0004125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax
property_value: IAO:0000589 "cuticle of fore leg" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000035
name: mid leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the paired appendage of the mesothorax that is posterior to the cuticle of a fore leg, anterior to the cuticle of a hind leg, and composed of cuticle of mesocoxa, cuticle of mesotrochanter, cuticle of mesofemur, cuticle of mesotibia, cuticle of mesotarsus, and cuticle of mesopretarsus." [] {creation_date="2021-04-03", http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg
relationship: anterior_to AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg
relationship: has_part AISM:0000064 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesocoxa
relationship: has_part AISM:0000068 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesotibia
relationship: has_part AISM:0000071 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesofemur
relationship: has_part AISM:0004172 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesotrochanter
relationship: has_part AISM:0004189 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesotarsus
relationship: has_part AISM:0004195 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopretarsus
relationship: part_of AISM:0004126 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax
relationship: posterior_to AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg
property_value: IAO:0000589 "cuticle of mid leg" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000036
name: hind leg {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the paired appendage of the metathorax that is posterior to the cuticle of a mid leg and composed of cuticle of metacoxa, cuticle of metatrochanter, cuticle of metafemur, cuticle of metatibia, cuticle of metatarsus, and cuticle of metapretarsus." [] {creation_date="2021-04-03", http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg
relationship: has_part AISM:0000065 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metacoxa
relationship: has_part AISM:0000069 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metatibia
relationship: has_part AISM:0000072 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metafemur
relationship: has_part AISM:0004173 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metatrochanter
relationship: has_part AISM:0004188 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metatarsus
relationship: has_part AISM:0004196 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapretarsus
relationship: part_of AISM:0004127 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax
relationship: posterior_to AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg
property_value: IAO:0000589 "cuticle of hind leg" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000037
name: fore wing {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the paired insect wing that is continuous with the mesonotum." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000033 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect wing
relationship: continuous_with AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesonotum
property_value: IAO:0000589 "cuticle of fore wing" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000038
name: hind wing {IAO:0000232="2021-12-08Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the paired insect wing that is continuous with the metanotum." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000033 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect wing
relationship: continuous_with AISM:0000169 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metanotum
property_value: IAO:0000589 "cuticle of hind wing" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000039
name: cuticular seta {creation_date="2020-11-11", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Seta (=macrotrichium): articulated hair with socket, formed by trichogen cell.\"", http://purl.org/dc/terms/modified="2021-12-10"}
def: "The unicellular cuticular evagination that constitutes a sclerite with its base surrounded by socket membrane." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
is_a: AISM:0000127 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! unicellular cuticular evagination
relationship: AISM:0000079 AISM:0000126 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by socket membrane

[Term]
id: AISM:0000040
name: cuticular spur {source="https://doi.org/10.1016/0020-7322(79)90013-8", AISM:0000171="Richards AG, Richards PA (1979) The cuticular protuberances of insects. International Journal of Insect Morphology and Embryology 8: 143–157. \n\n\"Multicellular protuberances without differentiation of specialized cells\"", http://purl.org/dc/terms/modified="2021-12-10"}
def: "The multicellular evagination of the cuticle that corresponds to an epithelial fold, composed of some sclerite that is encricled by a conjunctiva (moveable)." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
is_a: AISM:0000128 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multicellular cuticular evagination
relationship: AISM:0000079 AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by conjunctiva
property_value: curator_notes "The difference between an appendage and a spur is the lack of muscles attached to the spur, otherwise, the mandible would be also a spur. Spines are multicellular evaginations that are not encircled by conjunctivae. Moveable beetle horns are spurs while not moveable beetle horns are spines." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"}

[Term]
id: AISM:0000041
name: cuticular scale {http://purl.org/dc/terms/modified="2021-12-10"}
def: "The seta that is flat." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000039 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta
relationship: has_characteristic PATO:0002254 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! flattened

[Term]
id: AISM:0000042
name: labrum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Labrum: unpaired upper lip, connected with distal edge of clypeus.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the mouthpart and appendage that is attached to the clypeus by the clypeo-labral conjunctiva and to the proximal margin of the epipharynx." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000165 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart
relationship: adjacent_to AISM:0004019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus
relationship: continuous_with AISM:0004018 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeo-labral conjunctiva
property_value: IAO:0000589 "cuticle of labrum" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000043
name: insect mandible {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"The mandibles are the paired appendages of the 4th head segment and receive their innervation from the anterior part of the suboesophageal ganglion [...] They are primarily a compact, undivided and strongly sclerotized element without appendages.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the mouthpart and sclerite between the cuticle of the labrum and the cuticle of the insect maxilla that is attached to the head capsule by the oral foraminal conjunctiva and the cranio-mandibular muscle." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
is_a: AISM:0000165 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart
relationship: adjacent_to AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule
relationship: anterior_to AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect maxilla
relationship: continuous_with AISM:0000082 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cranio-mandibular muscle
relationship: continuous_with AISM:0000099 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! oral foraminal conjunctiva
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: posterior_to AISM:0000042 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labrum
property_value: IAO:0000589 "cuticle of insect mandible" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000044
name: insect maxilla {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Maxilla: head appendage of segment 5, innervated by maxillary nerve originating from intermediate part of suboesophageal complex; primarily composed of cardo, stipes, endite lobes (lacinia, galea) and maxillary palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the mouthpart appendage of the head capsule, between the cuticle of the insect mandible and the cuticle of the labium, composed of cuticle of cardo, which is attached to the cuticle of stipes by the cardo-stipital conjunctiva; the cuticle of stipes, which is attached to the cuticle of galea by the stipito-galeal conjunctiva, to the cuticle of lacinia by the stipito-lacinial conjunctiva, and to the cuticle of palpifer by the stipito-palpiferal conjunctiva; the cuticle of palpifer is attached to the cuticle of maxillary palpus by the palpifero-palpal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000165 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart
relationship: adjacent_to AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule
relationship: anterior_to AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: has_part AISM:0000018 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cardo
relationship: has_part AISM:0000023 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! galea
relationship: has_part AISM:0000026 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lacinia
relationship: has_part AISM:0000051 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpus
relationship: has_part AISM:0000110 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cardo-stipital conjunctiva
relationship: has_part AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes
relationship: has_part AISM:0004001 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifer
relationship: has_part AISM:0004009 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-lacinial conjunctiva
relationship: has_part AISM:0004010 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-palpiferal conjunctiva
relationship: has_part AISM:0004011 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-galeal conjunctiva
relationship: has_part AISM:0004012 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifero-palpal conjunctiva
relationship: posterior_to AISM:0000043 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mandible
property_value: IAO:0000589 "cuticle of insect maxilla" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000045
name: mesothoracic-metathoracic conjunctiva
def: "The conjunctiva of the insect thorax that connects the mesothorax and the metathorax." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0004126 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesothorax
relationship: continuous_with AISM:0004127 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metathorax
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax

[Term]
id: AISM:0000046
name: prothoracic-mesothoracic conjunctiva
def: "The conjunctiva of the insect thorax joining the prothorax and the mesothorax." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2020-03-18"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax
relationship: continuous_with AISM:0004126 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax

[Term]
id: AISM:0000047
name: pretarsus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pretarsus: apical element of leg bearing ungues; distinct and cylindrical in entognathous hexapods, strongly reduced in Insecta.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the insect leg that is attached to the cuticle of tarsus by the tarso-pretarsal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage
relationship: continuous_with AISM:0004187 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-pretarsal conjunctiva
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg
property_value: IAO:0000589 "cuticle of pretarsus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000048
name: ligula {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Ligula - The terminal lobes of the labium collectively, or a terminal part of the labium formed by the union of the lobes.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the cuticle of labium composed of the cuticle of glossa and cuticle of paraglossa jointly." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage
relationship: has_part AISM:0000049 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! glossa
relationship: has_part AISM:0000050 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraglossa
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! labium
property_value: IAO:0000589 "cuticle of ligula" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000049
name: glossa {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Glossa: paired inner endite lobes of the prementum.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the labium, and part of the ligula, that is attached to the prementum by the premental-glossal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage
relationship: adjacent_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum
relationship: continuous_with AISM:0004016 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-glossal conjunctiva
relationship: part_of AISM:0000048 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ligula
property_value: IAO:0000589 "cuticle of glossa" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000050
name: paraglossa {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraglossa: paired outer endite lobes of the prementum (labium).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the paired appendage of the labium, and part of the ligula, that is attached to the cuticle of prementum by the premental-paraglossal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage
relationship: adjacent_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum
relationship: continuous_with AISM:0004015 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-paraglossal conjunctiva
relationship: part_of AISM:0000048 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ligula
property_value: IAO:0000589 "cuticle of paraglossa" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000051
name: maxillary palpus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Palp: tactile appendage of maxilla\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the insect maxilla that is attached to the cuticle of palpifer by the palpifero-palpal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage
relationship: adjacent_to AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule
relationship: adjacent_to AISM:0004001 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifer
relationship: AISM:0000079 AISM:0004012 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by palpifero-palpal conjunctiva
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: has_part AISM:0002036 {creation_date="2023-04-13"} ! maxillary palpomere
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla
property_value: IAO:0000589 "cuticle of maxillary palpus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000052
name: mesonotum
def: "The notum or sclerite on the dorsal region of the mesothorax that is posterior to the pronotum, connected via the mesonoto-mesopleural conjuntiva to the dorsal margin of the mesopleuron, that is not adjacent to the mesocoxa, but attached to it by the mesocoxal muscle." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jcgiron"} ! insect sclerite
is_a: AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum
is_a: UBERON:0000061 ! anatomical structure
relationship: attaches_to AISM:0000085 {http://purl.org/dc/elements/1.1/contributor="jcgiron"} ! mesocoxal muscle
relationship: continuous_with AISM:0004219 {http://purl.org/dc/elements/1.1/contributor="jcgiron"} ! mesonoto-mesopleural conjuntiva
relationship: posterior_to AISM:0000059 {http://purl.org/dc/elements/1.1/contributor="jcgiron"} ! pronotum

[Term]
id: AISM:0000053
name: mesopectus {creation_date="2020-11-11"}
def: "The sclerite that is continuous with the basal mesocoxal conjunctiva and the basal wing conjunctiva and contains the mesofurca." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: continuous_with AISM:0000103 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal mesocoxal conjunctiva
relationship: continuous_with AISM:0004203 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal wing conjunctiva
relationship: has_part AISM:0000141 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesofurca

[Term]
id: AISM:0000054
name: mesotrochantin {creation_date="2020-11-11"}
def: "The trochantin that is located on the ventro-lateral region of the mesothorax and is attached to a mesocoxa and surrounded by the basal mesocoxal conjunctiva." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004135 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! trochantin
relationship: adjacent_to AISM:0000064 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesocoxa
relationship: AISM:0000079 AISM:0000103 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal mesocoxal conjunctiva

[Term]
id: AISM:0000055
name: protrochantin {creation_date="2020-11-11"}
def: "The trochantin that is located on the ventro-lateral region of the prothorax and is attached to a procoxa and surrounded by the basal procoxal conjunctiva." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004135 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! trochantin
relationship: adjacent_to AISM:0000066 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! procoxa
relationship: AISM:0000079 AISM:0000106 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal procoxal conjunctiva

[Term]
id: AISM:0000056
name: metatrochantin {creation_date="2020-11-11"}
def: "The trochantin that is located on the ventro-lateral region of the metathorax and is attached to a metacoxa and surrounded by the basal metacoxal conjunctiva." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004135 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! trochantin
relationship: adjacent_to AISM:0000065 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metacoxa
relationship: AISM:0000079 AISM:0000104 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal metacoxal conjunctiva

[Term]
id: AISM:0000057
name: prementum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prementum: distal main element of labium, bearing the endite lobes (glossa and paraglossa) and the labial palp.\""}
def: "The sclerite of the labium that is connected to the mentum by the mental-premental conjunctiva, to the palpiger by the premental-palpigeral conjunctiva, to the paraglossa by the premental-paraglossal conjunctiva, and to the glossa by the premental-glossal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: adjacent_to AISM:0000049 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! glossa
relationship: adjacent_to AISM:0000050 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraglossa
relationship: adjacent_to AISM:0004004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum
relationship: adjacent_to AISM:0004006 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpiger
relationship: continuous_with AISM:0004002 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mental-premental conjunctiva
relationship: continuous_with AISM:0004014 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-palpigeral conjunctiva
relationship: continuous_with AISM:0004015 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-paraglossal conjunctiva
relationship: continuous_with AISM:0004016 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-glossal conjunctiva
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium

[Term]
id: AISM:0000058
name: prepectus {creation_date="2020-11-11"}
def: "The sclerite that is posterior to the pronotum and receives the site of attachment of the dilutor muscle of the first thoracic spiracle." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
is_a: UBERON:0000061 ! anatomical structure

[Term]
id: AISM:0000059
name: pronotum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pronotum: prothoracic tergum.\""}
def: "The notum or sclerite on the dorsal region of the prothorax that is attached to cranial muscles, procoxal muscles, contiuous posterioirly with the neck membrane and with pronoto-propleural conjunctiva and not adjacent (not touching) to the procoxa." [] {http://purl.org/dc/terms/modified="2022-03-09", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-03-18"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
is_a: AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum
is_a: UBERON:0000061 ! anatomical structure
relationship: anteriorly_connected_to AISM:0000098 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! neck membrane
relationship: attaches_to AISM:0000080 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect cranial muscle
relationship: attaches_to AISM:0000145 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! procoxal muscle
relationship: continuous_with AISM:0004220 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! pronoto-propleural conjunctiva

[Term]
id: AISM:0000060
name: labial palpomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the mere that is part of the labial palpus." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000073 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mere
relationship: part_of AISM:0000024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labial palpus
property_value: IAO:0000589 "cuticle of labial palpomere" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000061
name: prosternum
def: "The sclerite on the ventral region of the prothorax that bears the profurca and is attached to the propleuro-prosternal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004130 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! sternum
relationship: continuous_with AISM:0004202 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! propleuro-prosternal conjunctiva
relationship: has_part AISM:0000143 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! profurca

[Term]
id: AISM:0000062
name: ring sclerite
def: "The sclerite that is cylindrical and encircles and is encircled by conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: AISM:0000078 AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles conjunctiva
relationship: AISM:0000079 AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by conjunctiva
relationship: has_characteristic PATO:0001873 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cylindrical

[Term]
id: AISM:0000063
name: appendage segment {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The ring sclerite that is part of an appendage and is attached to muscle." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000062 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring sclerite
relationship: continuous_with UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! somatic muscle
relationship: part_of AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage
property_value: IAO:0000589 "cuticle of appendage segment" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000064
name: mesocoxa {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of the mid leg that is attached to the latero-ventral region of the mesothorax by the basal mesocoxal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000077 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa
relationship: AISM:0000079 AISM:0000103 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal mesocoxal conjunctiva
relationship: part_of AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg
property_value: IAO:0000589 "cuticle of mesocoxa" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000065
name: metacoxa {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of the hind leg that is attached to the latero-ventral region of the metathorax by the basal metacoxal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000077 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa
relationship: AISM:0000079 AISM:0000104 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal metacoxal conjunctiva
relationship: part_of AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg
property_value: IAO:0000589 "cuticle of metacoxa" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000066
name: procoxa {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of the fore leg that is attached to the latero-ventral region of the prothorax by the basal procoxal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000077 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa
relationship: AISM:0000079 AISM:0000106 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal procoxal conjunctiva
relationship: part_of AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg
property_value: IAO:0000589 "cuticle of procoxa" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000067
name: protibia {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a fore leg attached to the distal margin of the profemur by the profemoro-protibial conjunctiva." [] {creation_date="2021-04-03", http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia
relationship: AISM:0000079 AISM:0004179 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by profemoro-protibial conjunctiva
relationship: part_of AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg
property_value: IAO:0000589 "cuticle of protibia" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000068
name: mesotibia {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a mid leg attached to the distal margin of the mesofemur by the mesofemoro-mesotibial conjunctiva." [] {creation_date="2021-04-03", http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia
relationship: AISM:0000079 AISM:0004180 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesofemoro-mesotibial conjunctiva
relationship: part_of AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg
property_value: IAO:0000589 "cuticle of mesotibia" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000069
name: metatibia {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a hind leg attached to the distal margin of the metafemur by the metafemoro-metatibial conjunctiva." [] {creation_date="2021-04-03", http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibia
relationship: AISM:0000079 AISM:0004181 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metafemoro-metatibial conjunctiva
relationship: part_of AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg
property_value: IAO:0000589 "cuticle of metatibia" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000070
name: profemur {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a fore leg attached to the distal margin of the protrochanter by the protrochantero-profemoral conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000076 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur
relationship: AISM:0000079 AISM:0000123 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by procoxal-protrochanteral conjunctiva
relationship: part_of AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg
property_value: IAO:0000589 "cuticle of profemur" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000071
name: mesofemur {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a mid leg attached to the distal margin of the mesotrochanter by the mesotrochantero-mesofemoral conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000076 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur
relationship: AISM:0000079 AISM:0000124 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesocoxal-mesotrochanteral conjunctiva
relationship: part_of AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg
property_value: IAO:0000589 "cuticle of mesofemur" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000072
name: metafemur {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a hind leg attached to the distal margin of the metatrochanter by the metatrochantero-metafemoral conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000076 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femur
relationship: AISM:0000079 AISM:0000125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metacoxal-metatrochanteral conjunctiva
relationship: part_of AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg
property_value: IAO:0000589 "cuticle of metafemur" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000073
name: mere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The ring sclerite that is part of an appendage and is not attached to somatic muscle." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000062 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring sclerite
relationship: part_of AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage
property_value: IAO:0000589 "cuticle of mere" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000074
name: tarsomere {AISM:0000171="\"Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tarsomere: subelement of tarsus in Insecta; number often taxon-specific, sometimes differing on legs of different segments (diagnostic value: tarsal formula).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the mere that is part of the tarsus." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000073 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mere
relationship: part_of AISM:0004169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus
property_value: IAO:0000589 "cuticle of tarsomere" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000075
name: tibia {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tibia: 4th element of leg; usually cylindrical and equipped with paired terminal spurs, often with rows of spines.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a leg attached to the distal margin of the femur by the femoro-tibial conjunctiva." [] {creation_date="2021-04-03", http://purl.org/dc/terms/modified="2021-12-08", comment="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000063 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment
relationship: AISM:0000079 AISM:0004178 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by femoro-tibial conjunctiva
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg
property_value: IAO:0000589 "cuticle of tibia" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000076
name: femur {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Femur: 3rd element of leg, often largest part.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a leg attached to the distal margin of the trochanter by the trochantero-femoral conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000063 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment
relationship: AISM:0000079 AISM:0004174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by trochantero-femoral conjunctiva
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg
property_value: IAO:0000589 "cuticle of femur" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000077
name: coxa {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxa: basal element of leg; articulated with pleural, sternal and usually also trochantinal elements of thoracic segment.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of the leg that is attached to the latero-ventral region of the insect thorax by the basal coxal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000063 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! appendage segment
relationship: AISM:0000079 AISM:0000173 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal coxal conjunctiva
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg
property_value: IAO:0000589 "cuticle of coxa" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000080
name: insect cranial muscle
def: "The somatic muscle that is attached to the head capsule." [] {creation_date="2021-04-04", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", http://purl.org/dc/terms/modified="2021-12-13"} ! somatic muscle
relationship: attaches_to AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! head capsule

[Term]
id: AISM:0000081
name: cranio-antennal muscle
def: "The somatic muscle that is attached to the head capsule and the antenna." [] {creation_date="2021-04-04", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0000080 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle
relationship: attaches_to AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! antenna

[Term]
id: AISM:0000082
name: cranio-mandibular muscle
def: "The somatic muscle that is attached to the head capsule and the insect mandible." [] {creation_date="2021-04-04", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0000080 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect cranial muscle
relationship: attaches_to AISM:0000043 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect mandible

[Term]
id: AISM:0000083
name: cranio-labial muscle
def: "The somatic muscle that is attached to the head capsule and the labium." [] {creation_date="2021-04-04", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000080 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle
relationship: attaches_to AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! labium

[Term]
id: AISM:0000084
name: cranio-labral muscle
def: "The somatic muscle that is attached to the head capsule and the labrum." [] {creation_date="2021-04-04", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0000080 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle
relationship: attaches_to AISM:0000042 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! labrum

[Term]
id: AISM:0000085
name: mesocoxal muscle {creation_date="2020-11-11"}
def: "The coxal muscle of the mesocoxa." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000086 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal muscle
relationship: attaches_to AISM:0000064 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesocoxa

[Term]
id: AISM:0000086
name: coxal muscle
def: "The somatic muscle that inserts in the coxa." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0002064 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect leg muscle
relationship: attaches_to AISM:0000077 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxa
property_value: curator_notes "All of the coxal muscles, except the second sternal-metacoxal muscle, are attached to the thorax." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}

[Term]
id: AISM:0000087
name: labium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The labium or lower lip forms the posterior (orthognathous head) or ventral (prognathous head) closure of the preoral space and of the salivarium. It is homologous to the maxilla (2nd maxilla) of crustaceans, but its proximal\nparts form a structural unit without a recognizable median line or suture.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the mouthpart appendage composed of the cuticle of submentum, which is attached by the submental-mental conjunctiva to the cuticle of mentum, which is attached by the mental-premental conjunctiva to the cuticle of prementum, which is attached to the cuticle of palpiger by the premental-palpigeral conjunctiva, the cuticle of paraglossa by the premental-paraglossal conjunctiva, and the cuticle of glossa by the premental-glossal conjunctiva; the cuticle of palpiger is attached by the palpigero-palpal conjunctiva to the cuticle of labial palpus." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000165 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mouthpart
relationship: has_part AISM:0000024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labial palpus
relationship: has_part AISM:0000048 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ligula
relationship: has_part AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum
relationship: has_part AISM:0004002 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mental-premental conjunctiva
relationship: has_part AISM:0004004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum
relationship: has_part AISM:0004005 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submentum
relationship: has_part AISM:0004006 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpiger
relationship: has_part AISM:0004013 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submental-mental conjunctiva
relationship: has_part AISM:0004014 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-palpigeral conjunctiva
relationship: has_part AISM:0004015 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-paraglossal conjunctiva
relationship: has_part AISM:0004016 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-glossal conjunctiva
relationship: has_part AISM:0004017 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpigero-palpal conjunctiva
property_value: IAO:0000589 "cuticle of labium" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000088
name: eye cuticle {creation_date="2020-11-11"}
def: "The elastic cuticle of the head capsule that is transparent and covers the eye." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000007 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle
relationship: has_characteristic PATO:0000964 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! transparent
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule

[Term]
id: AISM:0000089
name: insect ligament {creation_date="2020-11-11", IAO:0000232="Modified 2023-01-09 to specify insect ligament.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The resilin rich region that connects two sclerites." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000007 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle
relationship: continuous_with AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: part_of AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva

[Term]
id: AISM:0000090
name: cuticular tendon {AISM:0000171="Klass K-D (2001) The female abdomen of the viviparous earwig Hemimerus vosseleri (Insecta: Dermaptera: Hemimeridae), with a discussion of the postgenital abdomen of Insecta. Zoological Journal of the Linnean Society 131: 251–307. \n\nhttps://doi.org/10.1111/j.1096-3642.2001.tb02239.x \n\n\"tendon is used herein to designate membranous internal cuticular projections\""}
def: "The apodeme of elastic cuticle that is continuous with somatic muscle." [] {http://purl.org/dc/elements/1.1/contributor="2022-06-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000007 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle
is_a: AISM:0000188 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! apodeme
relationship: continuous_with UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! somatic muscle
property_value: curator_notes "The usually cylindircal evagination of the cuticle that is resilin rich and is continuous with somatic muscles." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"}

[Term]
id: AISM:0000091
name: insect trachea {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trachea: tube-shaped elements of the tracheal system.\"", IAO:0000232="Modified 2023-01-09 to specify insect trachea.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The branching invagination of elastic cuticle that is cylindrical and contains taenidia." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000007 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elastic cuticle
is_a: AISM:0000136 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination
relationship: has_characteristic PATO:0001873 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cylindrical
relationship: has_part AISM:0000140 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! taenidium

[Term]
id: AISM:0000093
name: hypopharynx {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypopharynx: median unpaired lobe between mouthparts and epipharynx; anterior (dorsal) surface continuous with anterior pharynx.\""}
def: "The conjunctiva of the insect head that is attached to the salivarium and to the oral foraminal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000099 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! oral foraminal conjunctiva
relationship: continuous_with AISM:0000159 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! salivarium
relationship: part_of AISM:0000107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head

[Term]
id: AISM:0000094
name: mesopleuro-metapleural conjunctiva
def: "The conjunctiva of the insect thorax that joins the mesopleuron and the metapleuron." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000119 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuron
relationship: continuous_with AISM:0004186 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopleuron
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax

[Term]
id: AISM:0000095
name: metasterno-metacoxal conjunctiva
def: "The conjunctiva of the mesothorax that joins the metasternum and the metacoxa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000065 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metacoxa
relationship: continuous_with AISM:0004232 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metasternum
relationship: part_of AISM:0004127 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax

[Term]
id: AISM:0000096
name: prosternal-procoxal conjunctiva
def: "The conjunctiva of the prothorax that joins the prosternum and the procoxa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000061 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prosternum
relationship: continuous_with AISM:0000066 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! procoxa
relationship: part_of AISM:0004125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax

[Term]
id: AISM:0000097
name: metapleuro-metacoxal conjunctiva
def: "The conjunctiva of the metathorax that joins the metapleuron and the metacoxa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000065 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metacoxa
relationship: continuous_with AISM:0000119 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuron
relationship: part_of AISM:0004127 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax

[Term]
id: AISM:0000098
name: neck membrane
def: "The conjuctiva that is continuous with the posterior margin of the head capsule and with the anterior margin of the prothorax, and bears cervical sclerites." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", http://purl.org/dc/terms/modified="2022-06-27"}
synonym: "cervical membrane" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cervical membrane: membrane connecting the head and prothorax.\""}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: AISM:0000078 AISM:0004141 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles cervical sclerite

[Term]
id: AISM:0000099
name: oral foraminal conjunctiva
def: "The conjunctiva of the insect head that connects the head capsule and the mouthparts." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: adjacent_to AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule
relationship: adjacent_to AISM:0000165 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mouthpart
relationship: part_of AISM:0000107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head

[Term]
id: AISM:0000100
name: pronoto-mesonotal conjunctiva
def: "The conjunctiva of the insect thorax that joins the pronotum and the mesonotum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum
relationship: continuous_with AISM:0000059 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax

[Term]
id: AISM:0000101
name: pronoto-mesopectal conjunctiva
def: "The conjunctiva that is attached to the pronotum and the mesopectus." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000053 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopectus
relationship: continuous_with AISM:0000059 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum

[Term]
id: AISM:0000102
name: ring conjunctiva
def: "The conjunctiva that encircles a ring sclerite." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: AISM:0000078 AISM:0000062 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles ring sclerite

[Term]
id: AISM:0000103
name: basal mesocoxal conjunctiva
def: "The conjunctiva that encircles the mesocoxa and connects it to the ventral and lateral regions of the mesothorax." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000173 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal coxal conjunctiva
relationship: continuous_with AISM:0004126 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax

[Term]
id: AISM:0000104
name: basal metacoxal conjunctiva
def: "The conjunctiva that encircles the metacoxa and connects it to the ventral and lateral regions of the metathorax." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000173 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! basal coxal conjunctiva
relationship: continuous_with AISM:0004127 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax

[Term]
id: AISM:0000105
name: epipharynx {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epipharynx: semimembranous or membranous posterior wall of labrum and roof of cibarium.\""}
def: "The conjunctiva of the insect head that is connected to the oral foraminal conjunctiva and to the distal margin of the labrum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000099 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! oral foraminal conjunctiva
relationship: part_of AISM:0000107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head

[Term]
id: AISM:0000106
name: basal procoxal conjunctiva
def: "The conjunctiva that encircles the procoxa and connects it to the ventral and lateral regions of the prothorax." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000173 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! basal coxal conjunctiva
relationship: continuous_with AISM:0004125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax

[Term]
id: AISM:0000107
name: insect head {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The head is a compact and complex tagma with a concentration of a broad array of structures und functions. It is equipped with sense organs such as the highly complex compound eyes and the antennae, an elaborate set of mouthparts, and a complex muscle apparatus. It also contains central elements of the nervous system, the anterior part of the digestive tract including the cibarium (preoral cavity) and the salivarium, and also neurohaemal organs.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticular region that is anterior (distal) to the neck membrane (encircled by the neck membrane) and contains the head capsule, the antenna, the eyes, mouthparts and surrounds the brain." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:6007289 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect tagmatic subdivision of integument
intersection_of: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle
intersection_of: UBERON:6007289 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect tagmatic subdivision of integument
intersection_of: anterior_to AISM:0000098 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! neck membrane
intersection_of: has_part AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! head capsule
relationship: AISM:0000079 AISM:0000098 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by neck membrane
relationship: anterior_to AISM:0000098 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! neck membrane
relationship: has_part AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! head capsule
relationship: has_part AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! antenna
relationship: has_part AISM:0000093 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hypopharynx
relationship: has_part AISM:0000099 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! oral foraminal conjunctiva
relationship: has_part AISM:0000105 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epipharynx
relationship: has_part AISM:0000112 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cranio-antennal conjunctiva
relationship: has_part AISM:0000165 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mouthpart
relationship: surrounds UBERON:0000955 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! brain
property_value: IAO:0000589 "cuticle of insect head" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000108
name: insect thorax {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The region of cuticle that is connected to some muscles of the fore and hind legs and is posterior to the neck membrane and aterior to the first abdominal spiracle." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
is_a: UBERON:6007289 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect tagmatic subdivision of integument
intersection_of: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle
intersection_of: UBERON:6007289 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect tagmatic subdivision of integument
intersection_of: anterior_to AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect abdomen
intersection_of: posterior_to AISM:0000098 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! neck membrane
relationship: anterior_to AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen
relationship: has_part AISM:0000085 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesocoxal muscle
relationship: has_part AISM:0000145 ! procoxal muscle
relationship: has_part AISM:0004125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax
relationship: has_part AISM:0004126 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax
relationship: has_part AISM:0004127 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax
relationship: posterior_to AISM:0000098 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! neck membrane
property_value: curator_notes "The hind leg muscles sometimes attach to the second abdominal sternite. The abdominal sopiracles are different in their structure from tghe thoracic spiracles as they are opened and closed by two articulating sclerites that are moved by two sets of muscles whereas the thoracic spiracles are closed by only one occlusor muscle and opened by the flexibility of the distal tracheal region. The border between the thorax and the abdomen is sometimes marked by the anterior first abdmonial tergal conjunctiva. In Hymenoptera, the border between the abdomen and the thorax cannot be defined as the anterior first abdmonial tergal conjunctiva is absent, the sclerite that receives muscles from the metacoxa also contains the first abdominal spiracle." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"}
property_value: IAO:0000589 "cuticle of insect thorax" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000109
name: insect abdomen {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The region of the cuticle that is an insect tagmatic subdivision of the integument, posterior to the thorax." [] {creation_date="2020-11-11", IAO:0000232="Modified 2024-01-25: added 'insect tagmatic subdivision of integument'.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
is_a: UBERON:6007289 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect tagmatic subdivision of integument
intersection_of: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle
intersection_of: UBERON:6007289 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect tagmatic subdivision of integument
intersection_of: posterior_to AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect thorax
relationship: depiction https://ndownloader.figshare.com/files/6014256/preview/6014256/preview.jpg
relationship: has_part AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen
relationship: has_part AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen
relationship: posterior_to AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thorax
property_value: curator_notes "The thorax is defined based on local properties (e.g. attachment sites of coxal muscles) and therefore we can reference this class for the definition of the abdomen." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"}
property_value: IAO:0000589 "cuticle of insect abdomen" xsd:string {comment="2023-04-13"}

[Term]
id: AISM:0000110
name: cardo-stipital conjunctiva
def: "The conjunctiva of the insect maxilla that connects the cardo and the stipes." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000018 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cardo
relationship: continuous_with AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla

[Term]
id: AISM:0000111
name: stipes {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Stipes: second element of maxilla, connected with cardo by a hinge; bearing endite lobes (galea and lacinia) and maxillary palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the sclerite of the insect maxilla that is attached to the cuticle of cardo by the cardo-stipital conjunctiva, attached to the cuticle of lacinia by the stipito-lacinial conjunctiva, attached to the cuticle of palpifer by the stipito-palpiferal conjunctiva, and attached to the cuticle of galea by the stipito-galeal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: adjacent_to AISM:0000018 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cardo
relationship: adjacent_to AISM:0000023 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! galea
relationship: adjacent_to AISM:0000026 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lacinia
relationship: adjacent_to AISM:0004001 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifer
relationship: continuous_with AISM:0000110 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cardo-stipital conjunctiva
relationship: continuous_with AISM:0004009 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-lacinial conjunctiva
relationship: continuous_with AISM:0004010 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-palpiferal conjunctiva
relationship: continuous_with AISM:0004011 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-galeal conjunctiva
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla
property_value: IAO:0000589 "cuticle of stipes" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000112
name: cranio-antennal conjunctiva
def: "The conjunctiva that encircles the base of the antenna (scape) and is encircled by the head capsule as the antennal foramen." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: AISM:0000078 AISM:0000113 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles scapus
relationship: AISM:0000079 AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by head capsule
relationship: continuous_with AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! head capsule

[Term]
id: AISM:0000113
name: scapus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\nScapus: basal element of antenna, with two muscles attached to the pedicellus.", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of the antenna that is connected to the head capsule and the antennifer by the basal antennal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
synonym: "antennomere 1" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000063 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! appendage segment
is_a: AISM:0004266 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antennomere
relationship: adjacent_to AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule
relationship: adjacent_to AISM:0000190 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antennifer
relationship: continuous_with AISM:0000112 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cranio-antennal conjunctiva
property_value: IAO:0000589 "cuticle of scapus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000114
name: scapal-pedicellar conjunctiva
def: "The conjunctiva of the antenna that connects the scapus and the pedicellus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000102 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring conjunctiva
relationship: AISM:0000078 AISM:0000115 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles pedicellus
relationship: AISM:0000079 AISM:0000113 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by scapus
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antenna

[Term]
id: AISM:0000115
name: pedicellus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pedicellus: second antennal segment in Insecta; contains Johnston’s organ and lacks intrinsic muscles.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of the antenna that is attached to the scapus by the scapal-pedicellar conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
synonym: "antennomere 2" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000063 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! appendage segment
is_a: AISM:0004266 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antennomere
relationship: AISM:0000079 AISM:0000114 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by scapal-pedicellar conjunctiva
property_value: IAO:0000589 "cuticle of pedicellus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000116
name: flagellomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the mere that is part of the antenna." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004266 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antennomere
relationship: distal_to AISM:0000115 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! pedicellus
property_value: curator_notes "Given the high number of flagellomeres occurring in some taxa, Arabic numerals are used instead of Roman numerals for practicality reasons." xsd:string {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
property_value: IAO:0000589 "cuticle of flagellomere" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000117
name: flagellomere 1 {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Flagellomere: segment of the flagellum.\"", IAO:0000232="Modified 2023-05-05: \"first\" replaced with \"1\"\ngmontanaro https://orcid.org/0000-0003-0836-1364", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the first flagellomere of the antenna, attached to the pedicel by the pedicel-first flagellomere conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
synonym: "antennomere 3" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! flagellomere
relationship: AISM:0000079 AISM:0000118 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by pedicellar-first flagellomeral conjunctiva
property_value: IAO:0000589 "cuticle of first flagellomere" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000118
name: pedicellar-first flagellomeral conjunctiva
def: "The conjunctiva of the antenna that connects the pedicellus and the first flagellomere." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: AISM:0000078 AISM:0000117 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles flagellomere 1
relationship: AISM:0000079 AISM:0000115 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by pedicellus
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antenna

[Term]
id: AISM:0000119
name: metapleuron
def: "The region of the cuticle on the lateral region of the metathorax that is attached to the metanotum and the metasternum, and is attached to the metacoxa by the metacoxal muscle and the basal metacoxal conjunctiva." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! pleuron
relationship: adjacent_to AISM:0000169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum
relationship: adjacent_to AISM:0004232 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metasternum
relationship: continuous_with AISM:0000104 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal metacoxal conjunctiva
relationship: continuous_with AISM:0000146 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metacoxal muscle

[Term]
id: AISM:0000120
name: propleuro-procoxal conjunctiva
def: "The conjunctiva of the prothorax that joins the propleuron and the procoxa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000066 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! procoxa
relationship: continuous_with AISM:0004142 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! propleuron
relationship: part_of AISM:0004125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax

[Term]
id: AISM:0000121
name: mesosternum
def: "The sclerite on the ventral region of the mesothorax that bears the mesofurca and is attached to the mesopleuro-mesosternal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004130 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum
relationship: continuous_with AISM:0004231 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopleuro-mesosternal conjunctiva
relationship: has_part AISM:0000141 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesofurca

[Term]
id: AISM:0000123
name: procoxal-protrochanteral conjunctiva
def: "The conjunctiva of the fore leg joining the distal margin of a procoxa and the proximal margin of a protrochanter." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0004170 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxal-trochanteral conjunctiva
relationship: part_of AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg

[Term]
id: AISM:0000124
name: mesocoxal-mesotrochanteral conjunctiva
def: "The conjunctiva of the mid leg joining the distal margin of a mesocoxa and the proximal margin of a mesotrochanter." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0004170 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal-trochanteral conjunctiva
relationship: part_of AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg

[Term]
id: AISM:0000125
name: metacoxal-metatrochanteral conjunctiva
def: "The conjunctiva of the hind leg joining the distal margin of a metacoxa and the proximal margin of a metatrochanter." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0004170 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxal-trochanteral conjunctiva
relationship: part_of AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg

[Term]
id: AISM:0000126
name: socket membrane {creation_date="2020-11-11"}
def: "The conjunctiva that corresponds to one epithelial cell and surrounds a sclerotized unicellular cuticular evagination." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: RO:0002008 CL:0000066 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell
property_value: curator_notes "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"}

[Term]
id: AISM:0000127
name: unicellular cuticular evagination
def: "The cuticular evagination that corresponds to the evagination on the membrane of a single cell and not to the evagination of a cell layer." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000027 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination
relationship: RO:0002008 CL:0000066 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell
property_value: curator_notes "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"}

[Term]
id: AISM:0000128
name: multicellular cuticular evagination {creation_date="2020-11-11"}
def: "The region of cuticle that corresponds to the evagination of the single layer epithelium." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000027 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination

[Term]
id: AISM:0000130
name: uniporous sensillum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The seta that has one opening distally." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0004304 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla
relationship: has_part AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta
relationship: has_part AISM:0000177 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! pore canal
property_value: curator_notes "Should coincide with 'exactly one' pore canal, but that violates OWL specs." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-23"}

[Term]
id: AISM:0000131
name: multiporous sensillum {creation_date="2020-11-11", IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Ando, T., Sekine, S., Inagaki, S., Misaki, K., Badel, L., Moriya, H., Sami, M.M., Itakura, Y., Chihara, T., Kazama, H. and Yonemura, S., 2019. Nanopore formation in the cuticle of an insect olfactory sensillum. Current Biology, 29(9), pp.1512-1520.\nhttps://www.sciencedirect.com/science/article/pii/S0960982219303410#fig4"}
def: "The seta that has multiple cuticular pores (openings of class III exocrine glands)." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0004304 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla
relationship: has_characteristic PATO:0000984 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! porous
relationship: has_part AISM:0000039 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular seta

[Term]
id: AISM:0000132
name: placoid sensillum {creation_date="2020-11-11"}
def: "The multiporous plate that is elongated." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000133 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multiporous plate
relationship: has_characteristic PATO:0001154 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elongated

[Term]
id: AISM:0000133
name: multiporous plate {creation_date="2020-11-11"}
def: "The multiporous sensillum that is flat." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000131 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! multiporous sensillum
relationship: has_characteristic PATO:0000407 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! flat

[Term]
id: AISM:0000134
name: cuticular exocrine gland duct {creation_date="2020-11-11", http://purl.org/dc/terms/modified="2021-12-10"}
def: "The branching cuticular invagination that corresponds to the invagination of the membrane of a single cell and does not contain taenidia." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000136 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination
relationship: RO:0002008 CL:0000066 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell
property_value: curator_notes "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"}

[Term]
id: AISM:0000135
name: insect spiracle {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spiracle: external opening of the tracheal system.\"", http://purl.org/dc/terms/modified="2023-01-09", IAO:0000232="Modified 2023-01-09: specifying insect spiracle.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The region of the cuticle that is continuous to the proximal region of a trachea and can be closed by muscles." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
is_a: UBERON:0000061 ! anatomical structure
relationship: attaches_to UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! somatic muscle

[Term]
id: AISM:0000136
name: branching cuticular invagination
def: "The cuticular ivagination that ramifies into umerous branches." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000006 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular invagination
relationship: has_characteristic PATO:0000402 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branched
property_value: curator_notes "Branching cuticular invaginations porvide important models for branchig morphogenesis." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"}

[Term]
id: AISM:0000137
name: malphigian tube {creation_date="2020-11-11"}
def: "The branching cuticular invagination that is located between the mid and hindgut." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
xref: http://purl.obolibrary.org/obo/UBERON_0001054
is_a: AISM:0000136 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination

[Term]
id: AISM:0000138
name: cuticular apophysis {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Apophysis: hollow cuticular invagination.\"", http://purl.org/dc/terms/modified="2021-12-10"}
def: "The cuticular invagination that is hollow." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000006 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular invagination
is_a: AISM:0000188 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! apodeme
relationship: RO:0002008 AISM:0000193 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular pit
property_value: curator_notes "The apophysis in HAO refers to an ivagination of the cuticle that is cylindrical as opposed to a ridge that is elongate. Beutel et al. 2014 differentiate apodemes from apophyses in that apodemes are solid and apophyses are hollow." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"}

[Term]
id: AISM:0000140
name: taenidium {creation_date="2020-11-11", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Taenidium: spiral-shaped strengthening ridge of the tracheae.\""}
def: "The coiled ridge in the wall of the trachea." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular ridge
relationship: has_characteristic PATO:0000404 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coiled

[Term]
id: AISM:0000141
name: mesofurca
def: "The furca of the mesothorax that is attached to the mesocoxa via muscle." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000144 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! furca
relationship: part_of AISM:0004126 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax

[Term]
id: AISM:0000142
name: metafurca
def: "The furca of the metathorax that is attached to the metacoxa via muscle." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000144 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! furca
relationship: part_of AISM:0004127 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax

[Term]
id: AISM:0000143
name: profurca
def: "The furca of the prothorax that is attached to the procoxa via muscle." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000144 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! furca
relationship: part_of AISM:0004125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax

[Term]
id: AISM:0000144
name: furca {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furca (=sternal apophysis, endosternite): endoskeletal element (entapophysis) of furcasternum; paired furcal arms often connected with pleural ridge by short muscle.\""}
def: "The apophysis that is located ventromedially on the thorax and is connected to the coxa via muscles." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
synonym: "endosternite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furca (=sternal apophysis, endosternite): endoskeletal element (entapophysis) of furcasternum; paired furcal arms often connected with pleural ridge by short muscle.\""}
is_a: AISM:0000136 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination
is_a: AISM:0000138 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular apophysis
is_a: UBERON:0000061 ! anatomical structure
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thorax
relationship: part_of BSPO:0000112 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ventro-medial region

[Term]
id: AISM:0000145
name: procoxal muscle {creation_date="2020-11-11"}
def: "The coxal muscle of the procoxa." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000086 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal muscle
relationship: attaches_to AISM:0000066 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! procoxa

[Term]
id: AISM:0000146
name: metacoxal muscle {creation_date="2020-11-11"}
def: "The coxal muscle of the metacoxa." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000086 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coxal muscle
relationship: attaches_to AISM:0000065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metacoxa

[Term]
id: AISM:0000147
name: femoral muscle
def: "The somatic muscle that inserts in the femur." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0002064 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect leg muscle
relationship: attaches_to AISM:0000076 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femur

[Term]
id: AISM:0000148
name: tibial muscle
def: "The somatic muscle that inserts in the tibia." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0002064 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect leg muscle
relationship: attaches_to AISM:0000075 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibia

[Term]
id: AISM:0000149
name: pretarsal muscle
def: "The somatic muscle that inserts in the pretarsus." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0002064 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect leg muscle
relationship: attaches_to AISM:0000047 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! pretarsus
property_value: curator_notes "There are usually two muscle bands of the pretarsal muscle, one is arising from the femur, the other from the tibia. The muscle usually inserts on a resilin rich basal sclerite of the pretarsus, the unguitractor plate." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"}

[Term]
id: AISM:0000150
name: profemoral muscle
def: "The somatic muscle that inserts in the profemur." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0000147 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femoral muscle
relationship: attaches_to AISM:0000070 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! profemur

[Term]
id: AISM:0000151
name: mesofemoral muscle
def: "The somatic muscle that inserts in the mesofemur." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0000147 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femoral muscle
relationship: attaches_to AISM:0000071 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesofemur

[Term]
id: AISM:0000152
name: metafemoral muscle
def: "The somatic muscle that inserts in the metafemur." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0000147 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! femoral muscle
relationship: attaches_to AISM:0000072 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metafemur

[Term]
id: AISM:0000153
name: protibial muscle
def: "The somatic muscle that inserts in the protibia." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0000148 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibial muscle
relationship: attaches_to AISM:0000067 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! protibia

[Term]
id: AISM:0000154
name: mesotibial muscle
def: "The somatic muscle that inserts in the mesotibia." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0000148 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibial muscle
relationship: attaches_to AISM:0000068 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesotibia

[Term]
id: AISM:0000155
name: metatibial muscle
def: "The somatic muscle that inserts in the metatibia." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0000148 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tibial muscle
relationship: attaches_to AISM:0000069 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metatibia

[Term]
id: AISM:0000156
name: cuticular fovea {http://purl.org/dc/terms/modified="2021-12-10"}
def: "The cuticular depression that is circular." [] {creation_date="2020-11-11", IAO:0000232="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000005 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular depression
relationship: has_characteristic PATO:0000411 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! circular

[Term]
id: AISM:0000157
name: cuticular groove {http://purl.org/dc/terms/modified="2021-12-10", IAO:0000232="former 'impression'\nimiko https://orcid.org/0000-0003-2938-9075"}
def: "The cuticular depression that is elongated and coincides with the distal side of an insect sclerite." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", IAO:0000232="Modified 2024-01-25: to reflect subclass of definiton\njgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000005 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular depression
relationship: has_characteristic PATO:0001154 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elongated
property_value: curator_notes "The cuticular depression (concavity on the surface of the cuticle) that does not correspond to a cuticular invagination (epithelial fold). The cuticule is less thick at the site of a cuticular impression." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-11"}

[Term]
id: AISM:0000158
name: cuticular ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ridge: cuticular strengthening ridge.\"\n\"They are not lines of fusion or molting lines.\"(p. 12)", http://purl.org/dc/terms/modified="2021-12-10"}
def: "The invagination on a sclerite that is elongated." [] {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000000 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular internal depression
relationship: has_characteristic PATO:0001154 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elongated
relationship: part_of AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite

[Term]
id: AISM:0000159
name: salivarium {def="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Salivarium: posterior part of preoral space between hypopharynx and labium, with opening of salivary ducts.\""}
def: "The conjunctiva in the head capsule that forms a pouch between the hypopharynx and the labium and bears the exocrine gland duct." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
is_a: AISM:0000160 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular pouch
relationship: continuous_with AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! labium
relationship: continuous_with AISM:0000093 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! hypopharynx
relationship: continuous_with AISM:0000134 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular exocrine gland duct
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule

[Term]
id: AISM:0000160
name: cuticular pouch {http://purl.org/dc/terms/modified="2021-12-10"}
def: "The invagination of the cuticle that is largely membranous." [] {creation_date="2020-11-12", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000006 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular invagination
relationship: has_part AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva

[Term]
id: AISM:0000161
name: discrimenal lamella
def: "The ridge that is in the sagittal line of the ventro-medial region of the thorax." [] {creation_date="2020-11-12", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular ridge
relationship: RO:0002008 BSPO:0000417 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with sagittal plane

[Term]
id: AISM:0000162
name: cuticular sulcus {http://purl.org/dc/terms/modified="2021-12-10"}
def: "The cuticular depression (concavity on cuticle surface) that corresponds with a cuticular ridge (an elongate cuticular invagination)." [] {creation_date="2020-11-12", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", http://purl.org/dc/terms/modified="2021-12-10"}
is_a: AISM:0000157 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular groove
relationship: RO:0002008 AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular ridge

[Term]
id: AISM:0000163
name: discrimen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Discrimen: longitudinal ridge medially dividing the sternum\""}
def: "The longitudinal (parallel to antero-posterior axis) sulcus that corresponds to the discrimenal lamella." [] {creation_date="2020-11-12", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000162 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sulcus
relationship: continuous_with AISM:0000161 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! discrimenal lamella
relationship: parallel_to BSPO:0000013 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis

[Term]
id: AISM:0000165
name: mouthpart {creation_date="2020-11-17", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the insect head that is encircled by the oral foraminal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21", http://purl.org/dc/terms/modified="2021-12-10"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect appendage
relationship: AISM:0000079 AISM:0000099 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by oral foraminal conjunctiva
relationship: part_of AISM:0000107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head
property_value: IAO:0000589 "cuticle of mouthpart" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000166
name: propleuro-procoxal articulation
def: "The insect articulation between the propleuron and the procoxa." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000002 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect articulation

[Term]
id: AISM:0000167
name: articular surface
def: "The region of cuticle where two sclerites meet." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of cuticle
relationship: adjacent_to AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite

[Term]
id: AISM:0000168
name: salivary sclerite
def: "The sclerite of the salivarium." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: part_of AISM:0000159 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! salivarium

[Term]
id: AISM:0000169
name: metanotum
def: "The notum or sclerite on the dorsal region of the metathorax that is posterior to the mesonotum, connected via the metanoto-metapleural conjuntiva to the dorsal margin of the metapleuron, that is not adjacent to the metacoxa, but attached to it by the metacoxal muscle." [] {http://purl.org/dc/elements/1.1/contributor="jcgiron", creation_date="2021-04-21"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
is_a: AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum
is_a: UBERON:0000061 ! anatomical structure
relationship: attaches_to AISM:0000146 {http://purl.org/dc/elements/1.1/contributor="jcgiron"} ! metacoxal muscle
relationship: continuous_with AISM:0004221 {http://purl.org/dc/elements/1.1/contributor="jcgiron"} ! metanoto-metapleural conjunctiva
relationship: posterior_to AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="jcgiron"} ! mesonotum

[Term]
id: AISM:0000170
name: metapectus
def: "The sclerite that is continuous with the basal metacoxal conjunctiva and the basal wing conjunctiva and contains the metafurca." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: continuous_with AISM:0000104 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal metacoxal conjunctiva
relationship: continuous_with AISM:0004203 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal wing conjunctiva
relationship: has_part AISM:0000142 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metafurca

[Term]
id: AISM:0000172
name: intertarsomeral conjunctiva
def: "The conjunctiva is encircled by a tarsomere that encircles another tarsomere." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000102 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva
relationship: AISM:0000078 AISM:0000074 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles tarsomere
relationship: AISM:0000079 AISM:0000074 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tarsomere
relationship: continuous_with AISM:0000074 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsomere

[Term]
id: AISM:0000173
name: basal coxal conjunctiva
def: "The conjunctiva that encircles the coxa and connects it to the ventral and lateral thoracic regions." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-17"}
is_a: AISM:0000102 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring conjunctiva
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax
property_value: curator_notes "These conjunctivae can be used as stable reference points in insects that poseess legs, and can be used to define sclerites on the lateral side of the thorax." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-17"}

[Term]
id: AISM:0000174
name: insect region of cuticle {IAO:0000232="Modified 2023-04-13: added insect to specify.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect region of integument that is part of the chitin-based cuticle." [] {creation_date="2020-11-23", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: BFO:0000004 ! independent continuant
relationship: part_of UBERON:0001001 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! chitin-based cuticle
relationship: part_of UBERON:6007284 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect region of integument
property_value: curator_notes "The AISM focuses on anatomical structures that are part of the insect (chitinous) cuticle. These structures are acellular regions of the integument. Regions of the insect cuticle with different mechanical properties (i.e. increased and descresed flexinility, thickness, and elasticity) are continuous with each other (e.g. sclerites are continuous with conjunctivae or resilin rich regions are continuous with regions with less resilin content)." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-11-23"}

[Term]
id: AISM:0000177
name: pore canal {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pore canals: thin perforations of the cuticle.\""}
def: "The orifice that is contained by the cuticle and connects the inside of the insect with the outside, is tubular, and whose diameter is smaller than 100 nm." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-04"}
is_a: UBERON:0000161 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! orifice
relationship: AISM:0000079 UBERON:0001002 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by cuticle
relationship: has_characteristic PATO:0001873 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cylindrical
relationship: RO:0002008 CL:0000066 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epithelial cell
property_value: curator_notes "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"}

[Term]
id: AISM:0000178
name: acantha {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Acanthae: hairs without sockets, one per hypodermal cell.\""}
def: "The solid cuticular protrusion that coincides with only one epidermal cell (smaller than the diameter of the epidermal cell)." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-04"}
is_a: AISM:0000028 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! solid cuticular protrusion
relationship: part_of AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: RO:0002008 CL:0000362 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with epidermal cell
property_value: curator_notes "Should coincide with 'exactly one' epithelial cell, but that violates OWL specs." xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-26"}

[Term]
id: AISM:0000185
name: sensillum chaeticum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum chaeticum: shorter than sensillum trichodeum, thick-walled.\""}
def: "The hairlike seta that is short and thick walled." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"}
is_a: AISM:0004304 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla
relationship: has_characteristic PATO:0002228 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! acuminate
relationship: has_part AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta

[Term]
id: AISM:0000186
name: sensillum trichodeum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum trichodeum: hair-like sensilla, seta associated with sensory cell.\""}
def: "The cuticular seta that is elongated and acuminate." [] {creation_date="2022-06-20", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004304 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla
relationship: has_characteristic PATO:0001154 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elongated
relationship: has_characteristic PATO:0002228 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! acuminate
relationship: has_part AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta
relationship: has_part AISM:0000039 {IAO:0000232="Modified 2023-01-11: added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular seta
property_value: curator_notes "Hairlike seta that is long." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"}

[Term]
id: AISM:0000187
name: sensillum coeloconicum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum coeloconicum: sensillum with modified seta in a cavity, with narrowed external opening of surrounding cuticle.\""}
def: "Seta that is located in the middle of a depression with narrowed external opening." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"}
is_a: AISM:0004304 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla

[Term]
id: AISM:0000188
name: apodeme {AISM:0000171="Klass K-D (2001) The female abdomen of the viviparous earwig Hemimerus vosseleri (Insecta: Dermaptera: Hemimeridae), with a discussion of the postgenital abdomen of Insecta. Zoological Journal of the Linnean Society 131: 251–307. \n\nhttps://doi.org/10.1111/j.1096-3642.2001.tb02239.x \n\n\"tendon is used herein to designate sclerotized internal cuticular projections\"", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Apodeme: solid cuticular invagination serving as muscle insertion area.\""}
def: "The solid cuticular invagination of a sclerite." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000000 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular internal depression
relationship: has_characteristic PATO:0001873 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cylindrical
relationship: part_of AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite

[Term]
id: AISM:0000189
name: sensillum basiconicum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum basiconicum: sensillum with rounded, conical seta.\""}
def: "The seta that is conical." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004304 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla
relationship: has_characteristic PATO:0002021 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conical
relationship: has_part AISM:0000039 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular seta

[Term]
id: AISM:0000190
name: antennifer {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Antennifer: small cephalic process articulating with the antenna.\""}
def: "The cuticular protrusion of the head capsule thag is continuous with the antenniferal-scapal conjunctiva and adjacent to the cuticle of the scapus" [] {creation_date="2022-06-20", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular protrusion
relationship: adjacent_to AISM:0000113 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! scapus
relationship: continuous_with AISM:0004007 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antenniferal-scapal conjunctiva
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule
property_value: curator_notes "The cuticular protrusion (process, protuberace) that bears the cranial articular surface of the cranio-antennal articulation." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-08"}

[Term]
id: AISM:0000191
name: tentorium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tentorium: cephalic endoskeleton, usually composed of paired anterior, posterior and dorsal tentorial arms and a transverse tentorial bridge (corpotentorium).\""}
def: "The solid, paired, branching cuticular invagination of the head capsule that is attached to the antenna and the mouthparts via muscles." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000136 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! branching cuticular invagination
is_a: AISM:0000188 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! apodeme
is_a: UBERON:0000061 ! anatomical structure
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! bilaterally paired
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! head capsule
property_value: curator_notes "The paired apophysis that connects the posterior (ventral in prognathous head) and anterior (dorsal in prognathous head) walls of the head capsule and serves as site of isertion of atennal and mouthpart muscles." xsd:string {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-02-11"}

[Term]
id: AISM:0000192
name: tentorio-antennal muscle
def: "The insect cranial muscle that is attached to the tentorium and to the antenna." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000080 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect cranial muscle
relationship: attaches_to AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antenna
relationship: attaches_to AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium

[Term]
id: AISM:0000193
name: cuticular pit {http://purl.org/dc/terms/modified="2021-12-10"}
def: "The cuticular depression that corresponds to an apophysis." [] {creation_date="2021-02-12", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000156 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular fovea
relationship: has_characteristic PATO:0002078 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! hollow
relationship: RO:0002008 AISM:0000138 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! coincident with cuticular apophysis

[Term]
id: AISM:0000194
name: anterior tentorial pit {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anterior tentorial pit (or groove): externally visible invagination area and origin of anterior tentorial arm; adjacent with dorsolateral clypeal margin.\""}
def: "The tentorial pit that correspods to the anterior (dorsal in prognathous head) end of the tentorium." [] {creation_date="2021-02-12", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000196 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tentorial pit
relationship: adjacent_to AISM:0004038 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior tentorial arm

[Term]
id: AISM:0000195
name: posterior tentorial pit {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Posterior tentorial pit (or groove): externally visible invagination of posterior part of head capsule and origin of posterior tentorial arm; adjacent with foramen occipitale or gula.\""}
def: "The tentorial pit that correspods to the posterior (ventral in prognathous head) end of the tentorium." [] {creation_date="2021-02-12", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000196 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tentorial pit
relationship: continuous_with AISM:0004037 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior tentorial arm

[Term]
id: AISM:0000196
name: tentorial pit
def: "The cuticular pit that correspods to the tentorium." [] {creation_date="2021-02-12", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", http://purl.org/dc/terms/modified="2021-12-10"}
is_a: AISM:0000193 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular pit

[Term]
id: AISM:0000197
name: arthropod foramen
def: "The foramen encircled by insect region of cuticle." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: UBERON:0000161 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! orifice
relationship: AISM:0000079 AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by insect region of cuticle

[Term]
id: AISM:0000198
name: antennal foramen
def: "The arthropod foramen of the head capsule with the antennifer and surrounds the scapus via the antenniferal-scapal conjunctiva." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "antennal socket" EXACT []
synonym: "torulus" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"antennal socket = torulus = basal socket of antenna\""}
is_a: AISM:0000197 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! arthropod foramen
relationship: AISM:0000079 AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by head capsule
relationship: AISM:0000079 AISM:0004007 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by antenniferal-scapal conjunctiva

[Term]
id: AISM:0000200
name: gonocoxa IX {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The paired sclerite of the postabdomen that is attached to the abdominal tergite IX by the abdominal tergite IX-gonocoxa IX conjunctiva and is articulated with abdominal tergite IX." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-03-19"}
synonym: "second coxopodite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""}
synonym: "second gonocoxite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""}
synonym: "second valvifer" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""}
is_a: AISM:0004301 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxite
relationship: continuous_with AISM:0000201 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX-gonocoxa IX conjunctiva
property_value: IAO:0000589 "cuticle of gonocoxa IX" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0000201
name: abdominal tergite IX-gonocoxa IX conjunctiva
def: "The conjunctiva of the postabdomen that connects the abdominal tergite IX and the gonocoxa IX." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-03-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000200 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxa IX
relationship: continuous_with AISM:0004117 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0000301
name: protarsomere {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The tarsomere that is part of the protarsus." [] {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000074 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! tarsomere
relationship: part_of AISM:0004190 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsus

[Term]
id: AISM:0000302
name: protarsomere I {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The protarsomere distal to the protibia and encircled by the protibio-protarsal conjunctiva." [] {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000301 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere
relationship: AISM:0000079 AISM:0004183 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protibio-protarsal conjunctiva
relationship: distal_to AISM:0000067 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protibia

[Term]
id: AISM:0000303
name: protarsomere II {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The protarsomere that is distal to the protarsomere I and is encircled by the protarsomere I-protarsomere II conjunctiva." [] {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000301 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere
relationship: AISM:0000079 AISM:0000319 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere I-protarsomere II conjunctiva
relationship: distal_to AISM:0000302 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere I

[Term]
id: AISM:0000304
name: protarsomere III {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The protarsomere that is distal to the protarsomere II and is encircled by the protarsomere II-protarsomere III conjunctiva." [] {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000301 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere
relationship: AISM:0000079 AISM:0000320 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere II-protarsomere III conjunctiva
relationship: distal_to AISM:0000303 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere II

[Term]
id: AISM:0000305
name: protarsomere IV {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The protarsomere that is distal to the protarsomere III and is encircled by the protarsomere III-protarsomere IV conjunctiva." [] {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000301 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere
relationship: AISM:0000079 AISM:0000321 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere III-protarsomere IV conjunctiva
relationship: distal_to AISM:0000304 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere III

[Term]
id: AISM:0000306
name: protarsomere V {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The protarsomere that is distal to the protarsomere IV and is encircled by the protarsomere IV-protarsomere V conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000301 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere
relationship: AISM:0000079 AISM:0000322 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! encircled by protarsomere IV-protarsomere V conjunctiva
relationship: distal_to AISM:0000305 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! protarsomere IV

[Term]
id: AISM:0000307
name: mesotarsomere {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The tarsomere that is part of the mesotarsus." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000074 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! tarsomere
relationship: part_of AISM:0004189 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus

[Term]
id: AISM:0000308
name: mesotarsomere I {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The mesotarsomere that is distal to the mesotibia and is encircled by the mesotibio-mesotarsal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000307 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere
relationship: AISM:0000079 AISM:0004184 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotibio-mesotarsal conjunctiva
relationship: distal_to AISM:0000068 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotibia

[Term]
id: AISM:0000309
name: mesotarsomere II {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The mesotarsomere that is distal to the mesotarsomere I and is encircled by the mesotarsomere I-mesotarsomere II conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000307 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere
relationship: AISM:0000079 AISM:0000323 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere I-mesotarsomere II conjunctiva
relationship: distal_to AISM:0000308 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere I

[Term]
id: AISM:0000310
name: mesotarsomere III {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The mesotarsomere that is distal to the mesotarsomere II and is encircled by the mesotarsomere II-mesotarsomere III conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000307 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere
relationship: AISM:0000079 AISM:0000324 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere II-mesotarsomere III conjunctiva
relationship: distal_to AISM:0000309 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere II

[Term]
id: AISM:0000311
name: mesotarsomere IV {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The mesotarsomere that is distal to the mesotarsomere III and is encircled by the mesotarsomere III-mesotarsomere IV conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000307 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere
relationship: AISM:0000079 AISM:0000325 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere III-mesotarsomere IV conjunctiva
relationship: distal_to AISM:0000310 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere III

[Term]
id: AISM:0000312
name: mesotarsomere V {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The mesotarsomere that is distal to the mesotarsomere IV and is encircled by the mesotarsomere IV-mesotarsomere V conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000307 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere
relationship: AISM:0000079 AISM:0000326 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere IV-mesotarsomere V conjunctiva
relationship: distal_to AISM:0000311 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere IV

[Term]
id: AISM:0000313
name: metatarsomere {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The tarsomere that is part of the metatarsus." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000074 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! tarsomere
relationship: part_of AISM:0004188 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus

[Term]
id: AISM:0000314
name: metatarsomere I {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The metatarsomere that is distal to the metatibia and is encircled by the metatibio-metatarsal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000313 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere
relationship: AISM:0000079 AISM:0004185 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatibio-metatarsal conjunctiva
relationship: distal_to AISM:0000069 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatibia

[Term]
id: AISM:0000315
name: metatarsomere II {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The metatarsomere that is distal to the metatarsomere I and is encircled by the metatarsomere I-metatarsomere II conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000313 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere
relationship: AISM:0000079 AISM:0000327 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere I-metatarsomere II conjunctiva
relationship: distal_to AISM:0000314 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere I

[Term]
id: AISM:0000316
name: metatarsomere III {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The metatarsomere that is distal to the metatarsomere II and is encircled by the metatarsomere II-metatarsomere III conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000313 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere
relationship: AISM:0000079 AISM:0000328 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere II-metatarsomere III conjunctiva
relationship: distal_to AISM:0000315 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere II

[Term]
id: AISM:0000317
name: metatarsomere IV {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The metatarsomere that is distal to the metatarsomere III and is encircled by the metatarsomere III-metatarsomere IV conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000313 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere
relationship: AISM:0000079 AISM:0000329 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere III-metatarsomere IV conjunctiva
relationship: distal_to AISM:0000316 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere III

[Term]
id: AISM:0000318
name: metatarsomere V {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The metatarsomere that is distal to the metatarsomere IV and is encircled by the metatarsomere IV-metatarsomere V conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000313 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere
relationship: AISM:0000079 AISM:0000330 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere IV-metatarsomere V conjunctiva
relationship: distal_to AISM:0000317 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere IV

[Term]
id: AISM:0000319
name: protarsomere I-protarsomere II conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere I and encircles protarsomere II." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000303 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere II
relationship: AISM:0000079 AISM:0000302 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere I
relationship: part_of AISM:0004190 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus

[Term]
id: AISM:0000320
name: protarsomere II-protarsomere III conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere II and encircles protarsomere III." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000304 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere III
relationship: AISM:0000079 AISM:0000303 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere II
relationship: part_of AISM:0004190 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus

[Term]
id: AISM:0000321
name: protarsomere III-protarsomere IV conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere III and encircles protarsomere IV." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000305 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere IV
relationship: AISM:0000079 AISM:0000304 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere III
relationship: part_of AISM:0004190 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus

[Term]
id: AISM:0000322
name: protarsomere IV-protarsomere V conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the protarsus, is encircled by protarsomere IV and encircles protarsomere V." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000306 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles protarsomere V
relationship: AISM:0000079 AISM:0000305 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by protarsomere IV
relationship: part_of AISM:0004190 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus

[Term]
id: AISM:0000323
name: mesotarsomere I-mesotarsomere II conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere I and encircles mesotarsomere II." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000309 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere II
relationship: AISM:0000079 AISM:0000308 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere I
relationship: part_of AISM:0004189 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus

[Term]
id: AISM:0000324
name: mesotarsomere II-mesotarsomere III conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere II and encircles mesotarsomere III." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000310 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere III
relationship: AISM:0000079 AISM:0000309 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere II
relationship: part_of AISM:0004189 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus

[Term]
id: AISM:0000325
name: mesotarsomere III-mesotarsomere IV conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere III and encircles mesotarsomere IV." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000311 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere IV
relationship: AISM:0000079 AISM:0000310 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere III
relationship: part_of AISM:0004189 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus

[Term]
id: AISM:0000326
name: mesotarsomere IV-mesotarsomere V conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the mesotarsus, is encircled by mesotarsomere IV and encircles mesotarsomere V." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000312 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles mesotarsomere V
relationship: AISM:0000079 AISM:0000311 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by mesotarsomere IV
relationship: part_of AISM:0004189 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus

[Term]
id: AISM:0000327
name: metatarsomere I-metatarsomere II conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere I and encircles metatarsomere II." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000315 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere II
relationship: AISM:0000079 AISM:0000314 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere I
relationship: part_of AISM:0004188 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus

[Term]
id: AISM:0000328
name: metatarsomere II-metatarsomere III conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere II and encircles metatarsomere III." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000316 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere III
relationship: AISM:0000079 AISM:0000315 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere II
relationship: part_of AISM:0004188 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus

[Term]
id: AISM:0000329
name: metatarsomere III-metatarsomere IV conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere III and encircles metatarsomere IV." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000317 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere IV
relationship: AISM:0000079 AISM:0000316 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere III
relationship: part_of AISM:0004188 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus

[Term]
id: AISM:0000330
name: metatarsomere IV-metatarsomere V conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the metatarsus, is encircled by metatarsomere IV and encircles metatarsomere V." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000318 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles metatarsomere V
relationship: AISM:0000079 AISM:0000317 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by metatarsomere IV
relationship: part_of AISM:0004188 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus

[Term]
id: AISM:0000331
name: protarsus with 5 protarsomeres {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The protarsus that is composed by protarsomeres 1-5." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0004190 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsus
relationship: has_part AISM:0000302 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsomere I
relationship: has_part AISM:0000303 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsomere II
relationship: has_part AISM:0000304 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsomere III
relationship: has_part AISM:0000305 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsomere IV
relationship: has_part AISM:0000306 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! protarsomere V

[Term]
id: AISM:0000332
name: mesotarsus with 5 mesotarsomeres {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The mesotarsus that is composed by mesotarsomeres 1-5." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0004189 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsus
relationship: has_part AISM:0000308 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere I
relationship: has_part AISM:0000309 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere II
relationship: has_part AISM:0000310 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere III
relationship: has_part AISM:0000311 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere IV
relationship: has_part AISM:0000312 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! mesotarsomere V

[Term]
id: AISM:0000333
name: metatarsus with 5 metatarsomeres {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The metatarsus that is composed by metatarsomeres 1-5." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0004188 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsus
relationship: has_part AISM:0000314 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere I
relationship: has_part AISM:0000315 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere II
relationship: has_part AISM:0000316 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere III
relationship: has_part AISM:0000317 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere IV
relationship: has_part AISM:0000318 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! metatarsomere V

[Term]
id: AISM:0000334
name: flagellomere 2 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The cuticle of the flagellomere that is distal to the flagellomere 1 and is encircled by the flagellomere 1-flagellomere 2 conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
synonym: "antennomere 4" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere
relationship: AISM:0000079 AISM:0000344 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 1-flagellomere 2 conjunctiva
relationship: distal_to AISM:0000117 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 1

[Term]
id: AISM:0000335
name: flagellomere 3 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The cuticle of the flagellomere that is distal to the flagellomere 2 and is encircled by the flagellomere 2-flagellomere 3 conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
synonym: "antennomere 5" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere
relationship: AISM:0000079 AISM:0000343 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 2-flagellomere 3 conjunctiva
relationship: distal_to AISM:0000334 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 2

[Term]
id: AISM:0000336
name: flagellomere 4 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The cuticle of the flagellomere that is distal to the flagellomere 3 and is encircled by the flagellomere 3-flagellomere 4 conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
synonym: "antennomere 6" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere
relationship: AISM:0000079 AISM:0000345 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 3-flagellomere 4 conjunctiva
relationship: distal_to AISM:0000335 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 3

[Term]
id: AISM:0000337
name: flagellomere 5 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The cuticle of the flagellomere that is distal to the flagellomere 4 and is encircled by the flagellomere 4-flagellomere 5 conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
synonym: "antennomere 7" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere
relationship: AISM:0000079 AISM:0000346 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 4-flagellomere 5 conjunctiva
relationship: distal_to AISM:0000336 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 4

[Term]
id: AISM:0000338
name: flagellomere 6 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The cuticle of the flagellomere that is distal to the flagellomere 5 and is encircled by the flagellomere 5-flagellomere 6 conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
synonym: "antennomere 8" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere
relationship: AISM:0000079 AISM:0000347 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 5-flagellomere 6 conjunctiva
relationship: distal_to AISM:0000337 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 5

[Term]
id: AISM:0000339
name: flagellomere 7 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The cuticle of the flagellomere that is distal to the flagellomere 6 and is encircled by the flagellomere 6-flagellomere 7 conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
synonym: "antennomere 9" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere
relationship: AISM:0000079 AISM:0000348 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 6-flagellomere 7 conjunctiva
relationship: distal_to AISM:0000338 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 6

[Term]
id: AISM:0000340
name: flagellomere 8 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The cuticle of the flagellomere that is distal to the flagellomere 7 and is encircled by the flagellomere 7-flagellomere 8 conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
synonym: "antennomere 10" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere
relationship: AISM:0000079 AISM:0000349 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 7-flagellomere 8 conjunctiva
relationship: distal_to AISM:0000339 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 7

[Term]
id: AISM:0000341
name: flagellomere 9 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The cuticle of the flagellomere that is distal to the flagellomere 8 and is encircled by the flagellomere 8-flagellomere 9 conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
synonym: "antennomere 11" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere
relationship: AISM:0000079 AISM:0000350 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 8-flagellomere 9 conjunctiva
relationship: distal_to AISM:0000340 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 8

[Term]
id: AISM:0000342
name: flagellomere 10 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The cuticle of the flagellomere that is distal to flagellomere 9 and is encircled by the flagellomere 9-flagellomere 10 conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
synonym: "antennomere 12" EXACT [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere
relationship: AISM:0000079 AISM:0000351 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 9-flagellomere 10 conjunctiva
relationship: distal_to AISM:0000341 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 9

[Term]
id: AISM:0000343
name: flagellomere 2-flagellomere 3 conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 2 and encircles the flagellomere 3." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000335 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 3
relationship: AISM:0000079 AISM:0000334 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 2
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna

[Term]
id: AISM:0000344
name: flagellomere 1-flagellomere 2 conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 1 and encircles the flagellomere 2." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000334 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 2
relationship: AISM:0000079 AISM:0000117 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 1
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna

[Term]
id: AISM:0000345
name: flagellomere 3-flagellomere 4 conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 3 and encircles the flagellomere 4." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000336 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 4
relationship: AISM:0000079 AISM:0000335 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 3
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna

[Term]
id: AISM:0000346
name: flagellomere 4-flagellomere 5 conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 4 and encircles the flagellomere 5." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000337 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 5
relationship: AISM:0000079 AISM:0000336 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 4
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna

[Term]
id: AISM:0000347
name: flagellomere 5-flagellomere 6 conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 5 and encircles the flagellomere 6." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000338 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 6
relationship: AISM:0000079 AISM:0000337 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 5
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna

[Term]
id: AISM:0000348
name: flagellomere 6-flagellomere 7 conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 6 and encircles the flagellomere 7." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000339 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 7
relationship: AISM:0000079 AISM:0000338 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 6
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna

[Term]
id: AISM:0000349
name: flagellomere 7-flagellomere 8 conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 7 and encircles the flagellomere 8." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000340 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 8
relationship: AISM:0000079 AISM:0000339 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 7
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna

[Term]
id: AISM:0000350
name: flagellomere 8-flagellomere 9 conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 8 and encircles the flagellomere 9." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000341 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 9
relationship: AISM:0000079 AISM:0000340 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 8
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna

[Term]
id: AISM:0000351
name: flagellomere 9-flagellomere 10 conjunctiva {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The conjunctiva that is part of the antenna, is encircled by the flagellomere 9 and encircles the flagellomere 10." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! conjunctiva
relationship: AISM:0000078 AISM:0000342 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircles flagellomere 10
relationship: AISM:0000079 AISM:0000341 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! encircled by flagellomere 9
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna

[Term]
id: AISM:0000352
name: microreticulate {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "A structural quality inhering in a bearer by virtue of the bearer's having its surface covered with microscopic cuticular grooves forming a network." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000353 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! reticulate
relationship: has_part AISM:0000157 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! cuticular groove

[Term]
id: AISM:0000353
name: reticulate {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "A structural quality inhering in a bearer by virtue of the bearer's presenting on its surface a network of raised and interconnected wrinkles." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: PATO:0000150 {IAO:0000232="Modified 2024-02-14: moved as subclass of texture\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! texture

[Term]
id: AISM:0000354
name: isodiametrically microreticulate {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "A structural quality inhering in a bearer by virtue of the bearer's being microreticulate and having meshes of isometric diameter." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000352 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! microreticulate
is_a: PATO:0001573 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! isometrical

[Term]
id: AISM:0000355
name: abdomen with 7 sternites {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The insect abdomen that has abdominal sternites 1-7 and does not have abdominal sternite 8." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! insect abdomen
relationship: has_part AISM:0004100 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite I
relationship: has_part AISM:0004104 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite II
relationship: has_part AISM:0004105 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite III
relationship: has_part AISM:0004106 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite IV
relationship: has_part AISM:0004107 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite V
relationship: has_part AISM:0004108 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite VI
relationship: has_part AISM:0004109 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite VII

[Term]
id: AISM:0000356
name: abdomen with 8 sternites {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The insect abdomen that has abdominal sternites 1-8 and does not have abdominal sternite 9." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! insect abdomen
relationship: has_part AISM:0004100 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite I
relationship: has_part AISM:0004104 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite II
relationship: has_part AISM:0004105 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite III
relationship: has_part AISM:0004106 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite IV
relationship: has_part AISM:0004107 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite V
relationship: has_part AISM:0004108 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite VI
relationship: has_part AISM:0004109 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite VII
relationship: has_part AISM:0004110 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! abdominal sternite VIII

[Term]
id: AISM:0000357
name: antenna with 8 antennomeres {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The antenna that has scapus, pedicellus, and flagellomeres 1-6, and does not have flagellomere 7." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna
relationship: has_part AISM:0000334 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 2
relationship: has_part AISM:0000335 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 3
relationship: has_part AISM:0000336 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 4
relationship: has_part AISM:0000337 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 5
relationship: has_part AISM:0000338 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 6

[Term]
id: AISM:0000358
name: antenna with 9 antennomeres {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
def: "The antenna that has scapus, pedicellus, and flagellomeres 1-7, and does not have flagellomere 8." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
is_a: AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! antenna
relationship: has_part AISM:0000334 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 2
relationship: has_part AISM:0000335 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 3
relationship: has_part AISM:0000336 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 4
relationship: has_part AISM:0000337 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 5
relationship: has_part AISM:0000338 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 6
relationship: has_part AISM:0000339 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"} ! flagellomere 7

[Term]
id: AISM:0000359
name: clypeal tooth {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular protrusion on the anterior margin of the clypeus." [] {http://purl.org/dc/terms/modified="18-11-2023", creation_date="2023-03-28", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000407 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="18-11-2023", creation_date="2023-03-28"} ! cuticular tooth

[Term]
id: AISM:0000360
name: medial clypeal tooth {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The clypeal tooth that is not bilaterally paired and located in the medial region." [] {creation_date="2022-10-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000359 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! clypeal tooth
relationship: located_in BSPO:0000083 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! medial region

[Term]
id: AISM:0000361
name: lateral clypeal tooth {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The clypeal tooth that is bilaterally paired and located in the lateral region." [] {creation_date="2022-10-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000359 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! clypeal tooth
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! bilaterally paired
relationship: located_in BSPO:0000082 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral region

[Term]
id: AISM:0000362
name: lateral clypeal tooth 1 {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The lateral clypeal tooth that is lateral to the medial region." [] {creation_date="2022-10-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000361 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! lateral clypeal tooth
relationship: AISM:0000011 BSPO:0000083 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral_to medial region

[Term]
id: AISM:0000363
name: lateral clypeal tooth 2 {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The lateral clypeal tooth that is lateral to the lateral clypeal tooth 1." [] {creation_date="2022-10-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000361 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! lateral clypeal tooth
relationship: AISM:0000011 AISM:0000362 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral_to lateral clypeal tooth 1

[Term]
id: AISM:0000364
name: lateral clypeal tooth 3 {creation_date="2022-10-30", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The lateral clypeal tooth that is lateral to the lateral clypeal tooth 2." [] {creation_date="2022-10-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000361 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2022-10-30"} ! lateral clypeal tooth
relationship: AISM:0000011 AISM:0000363 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! lateral_to lateral clypeal tooth 2

[Term]
id: AISM:0000365
name: tibial cuticular tooth {creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular protrusion of the cuticle of tibia." [] {http://purl.org/dc/terms/modified="18-11-2023", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"}
is_a: AISM:0000407 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="18-11-2023", creation_date="2023-03-28"} ! cuticular tooth
relationship: part_of AISM:0000075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! tibia

[Term]
id: AISM:0000366
name: protibial cuticular tooth {creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular protrusion of the cuticle of protibia." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"}
is_a: AISM:0000365 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! tibial cuticular tooth
relationship: part_of AISM:0000067 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! protibia

[Term]
id: AISM:0000367
name: dorsal protibial cuticular tooth {creation_date="2022-10-14", IAO:0000232="Modified and moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The protibial cuticular tooth on the posterior margin." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2023-05-03", creation_date="2023-03-28", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000366 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! protibial cuticular tooth

[Term]
id: AISM:0000368
name: dorsal protibial cuticular tooth 1 {http://purl.org/dc/terms/modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The dorsal protibial cuticular tooth that is proximal to the distal margin of the tibia." [] {creation_date="2023-03-30", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2023-05-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000367 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth

[Term]
id: AISM:0000369
name: dorsal protibial cuticular tooth 2 {http://purl.org/dc/terms/modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The dorsal protibial cuticular tooth that is proximal to the dorsal protibial cuticular tooth 1." [] {creation_date="2023-03-30", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2023-05-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000367 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth
relationship: proximal_to AISM:0000368 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-30"} ! dorsal protibial cuticular tooth 1

[Term]
id: AISM:0000370
name: dorsal protibial cuticular tooth 3 {http://purl.org/dc/terms/modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The dorsal protibial cuticular tooth that is proximal to the dorsal protibial cuticular tooth 2." [] {creation_date="2023-03-30", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2023-05-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000367 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth
relationship: proximal_to AISM:0000369 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-30"} ! dorsal protibial cuticular tooth 2

[Term]
id: AISM:0000371
name: dorsal protibial cuticular tooth 4 {http://purl.org/dc/terms/modified="2023-05-03", creation_date="2022-10-14", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The dorsal protibial cuticular tooth that is proximal to the dorsal protibial cuticular tooth 3." [] {creation_date="2023-03-30", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2023-05-03", comment="", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000367 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-28"} ! dorsal protibial cuticular tooth
relationship: proximal_to AISM:0000370 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-03-30"} ! dorsal protibial cuticular tooth 3

[Term]
id: AISM:0000372
name: left paramere {IAO:0000232="Modified 2023-04-15: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"}
def: "The cuticle of the paramere that is located in the left side of the body." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"}
property_value: IAO:0000589 "cuticle of left paramere" xsd:string {creation_date="2023-04-15"}

[Term]
id: AISM:0000373
name: right paramere {IAO:0000232="Modified 2023-04-15: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"}
def: "The cuticle of the paramere that is located in the right side of the body." [] {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-04"}
property_value: IAO:0000589 "cuticle of right paramere" xsd:string {creation_date="2023-04-15"}

[Term]
id: AISM:0000375
name: anterior groove of tergite VIII {creation_date="2023-06-04", IAO:0000232="Modified and moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular groove that is parallel and distal to the proximal carina of tergite VIII." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000157 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! cuticular groove
relationship: distal_to AISM:0000377 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! proximal carina of tergite VIII
relationship: parallel_to AISM:0000377 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! proximal carina of tergite VIII

[Term]
id: AISM:0000376
name: interpunctural distance {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The anatomical space adjacent to two cuticular punctures." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
property_value: curator_notes "Definition based on suggestions at https://github.com/obophenotype/uberon/issues/3188" xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"}

[Term]
id: AISM:0000377
name: proximal carina of tergite VIII {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular carina that is located on the proximal margin of the 8th tergite and is parallel to the left-right body axis." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
synonym: "pygidium basal ridge" EXACT [] {creation_date="2023-06-04", AISM:0000171="Tarasov, S. I., & Solodovnikov, A. Y. (2011). Phylogenetic analyses reveal reliable morphological markers to classify mega‐diversity in Onthophagini dung beetles (Coleoptera: Scarabaeidae: Scarabaeinae). Cladistics, 27(5), 490-528. https://doi.org/10.1111/j.1096-0031.2011.00351.x\n \nPage 526, character 30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000501 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! cuticular carina
relationship: parallel_to BSPO:0000017 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! left-right axis
property_value: curator_notes "In Scarabaeinae, this carina (when present) is located in the proximalmost margin of the surface of the 8th tergite (pygidium) that is not covered by elytra." xsd:string {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"}

[Term]
id: AISM:0000378
name: granulate cuticular puncture {creation_date="2023-06-04", AISM:0000171="Orbigny, H. d’ (1913) [1913-1914]. Synopsis des Onthophagides d’Afrique. Annales de la Société entomologique de France, 82 : 1-742.\nhttps://www.biodiversitylibrary.org/page/8239919\n\n\"la ponctuation peut être râpeuse ou granuleuse, c'est-à-dire composée de points dont le bord antérieur s'élève en une aspérité irrégulière, ou en un granule arrondi qui ordinaireauent échancre plus ou moins ce bord antérieur\" p. 4", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular puncture that has a cuticular granule on its anterior margin." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000524 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! cuticular puncture

[Term]
id: AISM:0000379
name: ocellate cuticular puncture {creation_date="2023-06-04", AISM:0000171="Orbigny, H. d’ (1913) [1913-1914]. Synopsis des Onthophagides d’Afrique. Annales de la Société entomologique de France, 82 : 1-742.\n\nhttps://www.biodiversitylibrary.org/page/8239919\n\n\"... soit grands et à fond plat, ou ocellés, c'est-à-dire grands et à fond convexe, ou ombiliqués, c'est-à-dire grands, peu profonds et ayant dans l'intérieur un petit point plus profond\" p. 4", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular puncture that is flattened." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}

[Term]
id: AISM:0000380
name: distal carina of tergite VIII {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular carina that is located along the distal margin of abdominal tergite VIII." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
synonym: "ribordo del margine ventrale del pigidio" EXACT [] {creation_date="2023-06-04", AISM:0000171="Marchisio, R., & Zunino, M. E. (2012). Il genere Copris Müller. Tassonomia, filogenesi e note di zoogeografia (Vol. 2, pp. 1-176). world biodiversity association onlus.\n\nPage 26", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000501 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! cuticular carina

[Term]
id: AISM:0000381
name: head margin at genoclypeal sulcus {creation_date="2023-06-04", IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The anatomical margin that is part of the anterior margin of the gena and of the lateral region of the posterior margin of the clypeus." [] {creation_date="2023-06-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: BSPO:0000006 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! anatomical margin
property_value: curator_notes "Corresponds with the region of the clypeal margin next to the distal end of the genoclypeal sulcus." xsd:string {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"}

[Term]
id: AISM:0000382
name: carina of vertex {IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-06", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular carina that is part of the vertex and parallel to the left-right body axis." [] {creation_date="2023-04-06", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
relationship: parallel_to BSPO:0000017 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! left-right axis

[Term]
id: AISM:0000383
name: clypeal carina {IAO:0000232="Moved from COLAO to AISM: 2023-05-08\ngmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-04-06", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular carina that is part of the clypeus and is parallel to the left-right body axis." [] {creation_date="2023-04-06", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
relationship: parallel_to BSPO:0000017 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-06-04"} ! left-right axis

[Term]
id: AISM:0000384
name: row of punctures {creation_date="2023-05-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "An anatomical row composed by cuticular punctures." [] {creation_date="2023-05-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: UBERON:0034926 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-03"} ! anatomical row
relationship: has_part AISM:0000524 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-03"} ! cuticular puncture

[Term]
id: AISM:0000385
name: clypeal margin {creation_date="2023-05-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The anatomical margin of the anterior region of clypeus." [] {creation_date="2023-05-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}

[Term]
id: AISM:0000386
name: genal margin {creation_date="2023-05-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The anatomical margin of the lateral region of the gena." [] {creation_date="2023-05-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}

[Term]
id: AISM:0000387
name: ventral conjunctiva of paramere {AISM:0000171="Rossini, M., Grebennikov, V., Merrien, T., Miraldo, A., Viljanen, H., & Tarasov, S. (2022). Paleogene forest fragmentation and out‐of‐Africa dispersal explain radiation of the Paleotropical dung beetle tribe Epactoidini trib. nov.(Coleoptera: Scarabaeinae). Systematic Entomology, 47(4), 655-667.\nhttps://doi.org/10.1111/syen.12564\n\nFigure 2d", creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The ventral region of the cuticle of paramere that has decreased thickness." [] {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
relationship: has_characteristic PATO:0000592 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! decreased thickness

[Term]
id: AISM:0000388
name: left ventral conjunctiva of paramere {creation_date="2023-05-08", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The ventral conjunctiva of the left paramere." [] {creation_date="2023-05-08", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000387 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! ventral conjunctiva of paramere
relationship: part_of AISM:0000372 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! left paramere

[Term]
id: AISM:0000389
name: right ventral conjunctiva of paramere {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The ventral conjunctiva of the right paramere." [] {creation_date="2023-05-04", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000387 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! ventral conjunctiva of paramere
relationship: part_of AISM:0000373 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-04"} ! right paramere

[Term]
id: AISM:0000390
name: protibial apex adjacent to protibio-protarsal articulation {creation_date="2023-05-10", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The region of the cuticle part of the distal posterior region of protibia and adjacent to the protibio-protarsal articulation." [] {creation_date="2023-05-10", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-10"} ! insect region of cuticle
relationship: adjacent_to AISM:0000391 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-10"} ! insect protibio-protarsal articulation

[Term]
id: AISM:0000391
name: insect protibio-protarsal articulation {creation_date="2023-05-10", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The articulation between the protibia and the protarsus." [] {creation_date="2023-05-10", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000002 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-10"} ! insect articulation

[Term]
id: AISM:0000392
name: parameres {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The region of the insect cuticle that has left and right parameres." [] {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! insect region of cuticle
relationship: has_part AISM:0000372 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! left paramere
relationship: has_part AISM:0000373 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! right paramere
property_value: curator_notes "This term has been created to indicate simultaneously left and right parameres, in order to be able to use on it the qualities \"symmetrical\" and \"asymmetrical\", which are not applicable to single parameres." xsd:string {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"}

[Term]
id: AISM:0000393
name: maxillary palpus with 4 palpomeres {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The maxillary palpus that has maxillary palpomeres I to IV but not maxillary palpomere V." [] {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000051 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpus
relationship: has_part AISM:0002037 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpomere I
relationship: has_part AISM:0002038 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpomere II
relationship: has_part AISM:0002039 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpomere III
relationship: has_part AISM:0002040 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! maxillary palpomere IV

[Term]
id: AISM:0000394
name: labial palpomere I {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The labial palpomere that is adjacent to the distal margin of the palpiger." [] {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000060 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere
relationship: AISM:0000079 AISM:0004017 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! encircled by palpigero-palpal conjunctiva

[Term]
id: AISM:0000395
name: labial palpomere II {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The labial palpomere that is adjacent to the distal margin of the labial palpomere I." [] {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000060 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere

[Term]
id: AISM:0000396
name: labial palpomere III {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The labial palpomere that is adjacent to the distal margin of the labial palpomere II." [] {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000060 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere

[Term]
id: AISM:0000397
name: labial palpus with 3 palpomeres {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The labial palpus that has labial palpomeres I to III." [] {creation_date="2023-05-30", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000024 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpus
relationship: has_part AISM:0000394 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere I
relationship: has_part AISM:0000395 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere II
relationship: has_part AISM:0000396 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-30"} ! labial palpomere III

[Term]
id: AISM:0000405
name: antero-distal margin {creation_date="2023-11-17", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The anatomical margin that overlaps with the distal side and the anterior side." [] {creation_date="2023-11-17", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: BSPO:0000671 ! anterior margin
is_a: BSPO:0000678 ! distal margin

[Term]
id: AISM:0000406
name: postero-distal margin {creation_date="2023-11-17", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The anatomical margin that overlaps with the distal side and the posterior side." [] {creation_date="2023-11-17", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: BSPO:0000672 ! posterior margin
is_a: BSPO:0000678 ! distal margin

[Term]
id: AISM:0000407
name: cuticular tooth {creation_date="2023-11-18", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular protrusion that is located on an anatomical margin." [] {creation_date="2023-11-18", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}

[Term]
id: AISM:0000408
name: setigerous cuticular puncture {creation_date="2023-12-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The cuticular puncture that encircles a cuticular seta." [] {creation_date="2023-12-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}

[Term]
id: AISM:0000409
name: granulate setigerous cuticular puncture {creation_date="2023-12-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The setigerous cuticular puncture that has a cuticular granule on its anterior margin." [] {creation_date="2023-12-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000408 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! setigerous cuticular puncture

[Term]
id: AISM:0000410
name: ocellate setigerous cuticular puncture {creation_date="2023-12-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The setigerous cuticular puncture that is flattened." [] {creation_date="2023-12-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}

[Term]
id: AISM:0000411
name: simple setigerous cuticular puncture {creation_date="2023-12-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The setigerous cuticular puncture that is flattened and does not have a cuticular granule." [] {creation_date="2023-12-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000408 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! setigerous cuticular puncture

[Term]
id: AISM:0000412
name: cuticle with setigerous punctures {creation_date="2023-12-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The region of the insect cuticle that is covered by a collection of setigerous cuticular punctures." [] {creation_date="2023-12-03", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! insect region of cuticle
relationship: has_member AISM:0000408 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! setigerous cuticular puncture
relationship: has_part UBERON:0034925 {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-12-03"} ! anatomical collection

[Term]
id: AISM:0000501
name: cuticular carina {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"an elevated ridge or keel, not necessarily high or acute\"", http://purl.org/dc/terms/modified="2021-12-10"}
def: "The protrusion on a sclerite that is elongated." [] {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330", creation_date="2021-05-06"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion
relationship: has_characteristic PATO:0001154 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! elongated
relationship: part_of AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! insect sclerite

[Term]
id: AISM:0000523
name: dorsal postabdomen
def: "Dorsal part of postabdomen." [] {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330", creation_date="2021-05-31"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! abdominal tergite
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! postabdomen

[Term]
id: AISM:0000524
name: cuticular puncture {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a small impression on the cuticle\"", http://purl.org/dc/terms/modified="2021-12-10"}
def: "The cuticular fovea that is small." [] {http://purl.org/dc/terms/modified="2021-12-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"}
is_a: AISM:0000156 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular fovea
relationship: has_characteristic PATO:0000587 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! decreased size

[Term]
id: AISM:0000525
name: cuticular granule {http://purl.org/dc/terms/modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a little grain or a minute grainlike elevation\"."}
def: "The cuticular protrusion of a sclerite that is small." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion
relationship: has_characteristic PATO:0000587 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! decreased size
relationship: part_of AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! insect sclerite

[Term]
id: AISM:0000526
name: cuticular tubercle {http://purl.org/dc/terms/modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a small knoblike or rounded protuberance\""}
def: "The cuticular protrusion of a sclerite that is rounded (circular)." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion
relationship: has_characteristic PATO:0000411 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! circular
relationship: part_of AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! insect sclerite

[Term]
id: AISM:0000527
name: cuticular spine {AISM:0000171="Richards AG, Richards PA (1979) The cuticular protuberances of insects. International Journal of Insect Morphology and Embryology 8: 143–157. \n\n\"Multicellular protuberances without differentiation of specialized cells [...] evaginations, non-movable\"", source="https://doi.org/10.1016/0020-7322(79)90013-8", http://purl.org/dc/terms/modified="2021-12-10"}
def: "The cuticular protrusion of a sclerite that is sharp." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular protrusion
relationship: has_characteristic PATO:0001419 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! sharp
relationship: part_of AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! insect sclerite

[Term]
id: AISM:0000528
name: granulated cuticle {http://purl.org/dc/terms/modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"covered with or made up of very small grains or granules\""}
def: "The region of cuticle that bears an anatomical collection that is composed of granules." [] {http://purl.org/dc/terms/modified="2021-12-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_member AISM:0000525 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular granule
relationship: has_part UBERON:0034925 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! anatomical collection

[Term]
id: AISM:0000529
name: punctate cuticle {http://purl.org/dc/terms/modified="2021-12-10", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"set with fine, impressed points or punctures appearing as pin-pricks\""}
def: "The region of cuticle that bears an anatomical collection that is composed of punctures." [] {http://purl.org/dc/terms/modified="20021-12-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_member AISM:0000524 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular puncture
relationship: has_part UBERON:0034925 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! anatomical collection

[Term]
id: AISM:0000530
name: setose cuticle {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"furnished or covered with setae or stiff hairs\"", http://purl.org/dc/terms/modified="2021-12-10"}
def: "The region of the cuticle that bears an anatomical collection that is composed of setae." [] {http://purl.org/dc/terms/modified="2021-12-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-07-21"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_member AISM:0000039 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular seta
relationship: has_part UBERON:0034925 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! anatomical collection

[Term]
id: AISM:0000531
name: conjunctival keel
def: "The cuticular evagination constituted by conjunctiva that is elongated." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"}
is_a: AISM:0000027 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular evagination
relationship: has_characteristic PATO:0001154 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! elongated
relationship: part_of AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! conjunctiva

[Term]
id: AISM:0000532
name: conjunctival tubercle
def: "The cuticular evagination constituted by conjunctiva that is circular." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"}
is_a: AISM:0000027 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! cuticular evagination
relationship: has_characteristic PATO:0000411 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! circular
relationship: part_of AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330"} ! conjunctiva

[Term]
id: AISM:0000534
name: conjunctival fold
def: "The cuticular depression constituted by conjunctiva that is elongated." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"}
is_a: AISM:0000005 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular depression
relationship: has_characteristic PATO:0001154 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! elongated
relationship: part_of AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva

[Term]
id: AISM:0002002
name: anterior tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Anterior (ventral) basal margin of the scape\""}
def: "The cranio-antennal muscle that is attached to the dorsal tentorial arm and the proximal margin of the scapus." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000081 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle
relationship: attaches_to AISM:0004039 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal tentorial arm

[Term]
id: AISM:0002003
name: posterior tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Posterior (dorsal) basal margin of the scape\""}
def: "The cranio-antennal muscle that is attached to the dorsal or anterior tentorial arm and the proximo-dorsal margin of the scapus." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000081 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle

[Term]
id: AISM:0002004
name: lateral tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Lateral basal margin of the scape\""}
def: "The cranio-antennal muscle that extends between the dorsal or anterior tentorial arm and the proximo-lateral margin of the scapus." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000081 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle

[Term]
id: AISM:0002005
name: medial tentorio-scapal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior or dorsal tentorial arms\"\n\n\"Insertion: Mesal basal margin of the scape\""}
def: "The cranio-antennal muscle that is attached to the dorsal or anterior tentorial arm and the proximal margin of the scapus." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000081 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle
relationship: attaches_to AISM:0004039 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal tentorial arm

[Term]
id: AISM:0002006
name: fronto-pedicellar muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Frons\"\n\n\"Insertion: Lateral edge of the pedicel\""}
def: "The cranio-antennal muscle that is attached to the frons and the pedicellus." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000081 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle
relationship: attaches_to AISM:0000115 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! pedicellus
relationship: attaches_to AISM:0004020 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frons

[Term]
id: AISM:0002007
name: lateral scapo-pedicellar muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Dorsal or dorsolateral wall of the scape\"\n\n\"Insertion: Lateral or dorsolateral wall of the pedicel\""}
def: "The cranio-antennal muscle that is attached to the dorsal or dorsolateral regions of the scapus and the lateral or dorsolateral regions of the pedicellus." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000081 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle

[Term]
id: AISM:0002008
name: medial scapo-pedicellar muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal or dorsomesal wall of the scape\"\n\n\"Insertion: Mesal, anteriomesal or anterior edge of the pedicel\""}
def: "The cranio-antennal muscle that is attached to the scapus and the pedicellus." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000081 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-antennal muscle
relationship: attaches_to AISM:0000113 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! scapus
relationship: attaches_to AISM:0000115 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! pedicellus

[Term]
id: AISM:0002009
name: frontolabral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesally on the frons or on the antennal base\"\n\n\"Insertion: Mesally on the outer basal wall of the labrum\""}
def: "The cranio-labral muscle that is attached to the frons and the labrum." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000084 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle
relationship: attaches_to AISM:0004020 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frons

[Term]
id: AISM:0002010
name: epistoepipharyngeal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Epistomal sulcus\"\n\n\"Insertion: Basal labral wall\""}
def: "The cranio-labral muscle that is attached to the frontoclypeal ridge and the labrum." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000084 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle
relationship: attaches_to AISM:0004034 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frontoclypeal ridge

[Term]
id: AISM:0002011
name: frontoepypharyngeal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesally on the frons or on the antennal base,\nusually on the same level as musculus\nfrontolabralis\"\n\n\"Insertion: Basal labral wall or tormae\""}
def: "The cranio-labral muscle that is attached to the frons and the tormae." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000084 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle
relationship: attaches_to AISM:0002012 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! torma
relationship: attaches_to AISM:0004020 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frons

[Term]
id: AISM:0002012
name: torma {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tormae: lateral apodemes of labral base\""}
def: "The apodeme at either side of the proximal margin of the labrum." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000188 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! apodeme

[Term]
id: AISM:0002013
name: transversal labral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Ventral labral wall\"\n\n\"Insertion: Ventral labral wall of the other side\""}
def: "The cranio-labral muscle that extends betwen the sides of  the labrum." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000084 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labral muscle

[Term]
id: AISM:0002014
name: internal cranio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Ventral, posterior, lateral and/or dorsal parts of\nthe head capsule and/or posterior and\nanterior tentorial arms\"\n\n\"Insertion: Tendon that inserts at the median edge of the\nmandible\""}
def: "The cranio-mandibular muscle that is attached to the head capsule and the insect mandible." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000082 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle

[Term]
id: AISM:0002017
name: posteroexternal cranio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Gena and postgena\"\n\n\"Insertion: Tendon that inserts at the lateral edge of the mandible\""}
def: "The cranio-mandibular muscle that extends between the gena and the lateral margin of the insect mandible." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000082 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle
relationship: attaches_to AISM:0004026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! gena

[Term]
id: AISM:0002018
name: anteroexternal cranio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Gena, below the compound eye\"\n\n\"Insertion: With a tendon on the mandible, posterior to the anterior articulation complex\""}
def: "The cranio-mandibular muscle that is attached to the gena and the insect mandible." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000082 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle
relationship: attaches_to AISM:0004026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! gena

[Term]
id: AISM:0002019
name: hypopharyngeal suspensorium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Suspensorium (=fulturae, hypopharyngeal arms, oral arms): sclerotized strengthening elements of proximal hypopharynx.\""}
def: "The hypopharyngeal sclerite on the proximal region of the hypopharynx." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2022-06-22"}
synonym: "fulturae" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"}
synonym: "hypopharyngeal arms" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"}
synonym: "oral arms" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"}
is_a: AISM:0004275 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hypopharyngeal sclerite

[Term]
id: AISM:0002021
name: hypopharyngeomandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Small sclerite close to the loral arm\n(Thermobia), scleroticed arm that elongates\nthe loral arm (Neoptera)\"\n\n\"Insertion: Inner side of the lateral wall of the mandible\""}
def: "The cranio-mandibular muscle that is attached to the suspensorium and the insect mandible." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000082 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle
relationship: attaches_to AISM:0002019 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! hypopharyngeal suspensorium

[Term]
id: AISM:0002022
name: superolateral tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior and dorsal tentorial arm\"\n\n\"Insertion: Outer basal edge of the mandibular body, between processus paratentorialis and posterior articulation\""}
def: "The cranio-mandibular muscle that is attached to the dorsal tentorial arm and the proximal margin of the insect mandible." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000082 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle
relationship: attaches_to AISM:0004039 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal tentorial arm

[Term]
id: AISM:0002023
name: inferolateral tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior tentorial arm\"\n\n\"Insertion: Ventral basal margin of the mandible\""}
def: "The cranio-mandibular muscle that extends between the anterior tentorial arm and the proximal-ventral margin of the insect mandible." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000082 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle
relationship: attaches_to AISM:0004038 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! anterior tentorial arm

[Term]
id: AISM:0002024
name: superomedial tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior and dorsal tentorial arm below musculus tentoriomandibularis externus dorsalis\"\n\n\"Insertion: Upper inner end of the mandible, just below the posterior mandibular condyle\""}
def: "The cranio-mandibular muscle that is attached to the anterior tentorial arm and the insect mandible." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000082 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle
relationship: attaches_to AISM:0004038 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! anterior tentorial arm

[Term]
id: AISM:0002025
name: inferomedial tentorio-mandibular muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior tentorial arm, below musculus tentoriomandibularis lateralis superior\"\n\n\"Insertion: Mediodorsal wall of the mandibular cavity\""}
def: "The cranio-mandibular muscle that extends between the anterior tentorial arm and the dorso-medial region of the insect mandible." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000082 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-mandibular muscle
relationship: attaches_to AISM:0004038 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! anterior tentorial arm

[Term]
id: AISM:0002026
name: insect cranio-maxillar muscle
def: "The somatic muscle that is attached to the head capsule and the insect maxilla." [] {creation_date="2021-04-04", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", http://purl.org/dc/terms/modified="2021-12-13"} ! somatic muscle
relationship: attaches_to AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect maxilla

[Term]
id: AISM:0002027
name: cranio-cardinal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Postgena and gena\"\n\n\"Insertion: Basal cardinal process\""}
def: "The insect cranio-maxillar muscle that is attached to the gena and the cardo." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0000018 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cardo
relationship: attaches_to AISM:0004026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! gena

[Term]
id: AISM:0002028
name: cranio-lacinial muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Posterior part of the gena\"\n\n\"Insertion: Basal edge of lacinia\""}
def: "The insect cranio-maxillar muscle that is attached to the gena and the lacinia." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0000026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! lacinia
relationship: attaches_to AISM:0004026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! gena

[Term]
id: AISM:0002029
name: tentorio-cardinal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Tentorium\"\n\n\"Insertion: Distal part of the cardo, close to the carostipital\nsulcus\""}
def: "The insect cranio-maxillar muscle that is attached to the tentorium and the cardo." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0000018 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cardo
relationship: attaches_to AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorium

[Term]
id: AISM:0002030
name: anterior tentorio-stipital muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Tentorium\"\n\n\"Insertion: Stipital ridge\""}
def: "The insect cranio-maxillar muscle that is attached to the tentorium and the stipital ridge." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorium
relationship: attaches_to AISM:0002031 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipital ridge

[Term]
id: AISM:0002031
name: stipital ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043"}
def: "The ridge that is part of the stipes." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cuticular ridge
relationship: part_of AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipes

[Term]
id: AISM:0002032
name: posterior tentorio-stipital muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Tentorium\"\n\n\"Insertion: Basally on the stipes, close to the stipitocardinal\nsuture\""}
def: "The insect cranio-maxillar muscle that is attached to the tentorium and the stipes." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipes
relationship: attaches_to AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorium

[Term]
id: AISM:0002033
name: stipito-lacinial muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Lateral wall of the stipes, basal to the maxillary\npalpus\"\n\n\"Insertion: Basal edge of lacinia, in some cases common\ntendon with 0mx4\""}
def: "The insect cranio-maxillar muscle that is attached to the stipes and the lacinia." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0000026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! lacinia
relationship: attaches_to AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipes

[Term]
id: AISM:0002034
name: stipito-galeal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Lateral wall of the stipes, basal to the maxillary\npalpus\"\n\n\"Insertion: Basal edge of galea\""}
def: "The insect cranio-maxillar muscle that is attached to the stipes and the galea." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0000023 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! galea
relationship: attaches_to AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipes

[Term]
id: AISM:0002035
name: stipito-palpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x"}
def: "The insect cranio-maxillar muscle that is attached to the stipes and the maxillary palpus." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0000051 {def="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpus
relationship: attaches_to AISM:0000111 {def="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! stipes

[Term]
id: AISM:0002036
name: maxillary palpomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the mere that is part of the maxillary palpus." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000073 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mere
relationship: part_of AISM:0000051 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpus
property_value: IAO:0000589 "cuticle of maxillary palpomere" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0002037
name: maxillary palpomere I {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the palpiger and to the proximal margin of the maxillary palpomere II." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere
relationship: AISM:0000079 AISM:0004017 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by palpigero-palpal conjunctiva
property_value: IAO:0000589 "cuticle of maxillary palpomere I" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0002038
name: maxillary palpomere II {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere I." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere
property_value: IAO:0000589 "cuticle of maxillary palpomere II" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0002039
name: maxillary palpomere III {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere II." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere
property_value: IAO:0000589 "cuticle of maxillary palpomere III" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0002040
name: maxillary palpomere IV {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere III." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpomere
property_value: IAO:0000589 "cuticle of maxillary palpomere IV" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0002041
name: maxillary palpomere V {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the maxillary palpomere that is attached to the distal margin of the maxillary palpomere IV." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002036 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere
property_value: IAO:0000589 "cuticle of maxillary palpomere V" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0002042
name: first maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Basal edge of palpomere 1\"\n\n\"Insertion: Basal edge of palpomere 2\""}
def: "The insect cranio-maxillar muscle that is attached to the first maxillar palpomere and  the second maxillar palpomere." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0002037 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere I
relationship: attaches_to AISM:0002038 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere II

[Term]
id: AISM:0002043
name: second maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal edge of palpomere 2\"\n\n\"Insertion: Mesal edge of palpomere 3\""}
def: "The insect cranio-maxillar muscle that is attached to the second maxillar palpomere and  the third maxillar palpomere." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0002038 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere II
relationship: attaches_to AISM:0002039 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere III

[Term]
id: AISM:0002044
name: third maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Basal edge of palpomere 3\"\n\n\"Insertion: Basal edge of palpomere 4\""}
def: "The insect cranio-maxillar muscle that is attached to the third maxillar palpomere and  the fourth maxillar palpomere." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0002039 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere III
relationship: attaches_to AISM:0002040 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere IV

[Term]
id: AISM:0002045
name: fourth maxillar palpopalpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal edge of palpomere 4\"\n\n\"Insertion: Mesal edge of palpomere 5\""}
def: "The insect cranio-maxillar muscle that is attached to the fourth maxillar palpomere and  the fifth maxillar palpomere." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002026 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-maxillar muscle
relationship: attaches_to AISM:0002040 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere IV
relationship: attaches_to AISM:0002041 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! maxillary palpomere V

[Term]
id: AISM:0002047
name: postoccipitoglossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Postoccipital phragma\"\n\n\"Insertion: glossa\""}
def: "The cranio-labial muscle that is attached to the postoccipital phragma and  the glossa." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000083 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle
relationship: attaches_to AISM:0000049 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! glossa
relationship: attaches_to AISM:0002049 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! postoccipital phragma

[Term]
id: AISM:0002048
name: phragma {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Phragma: large, ridge-shaped internal apodeme.\"\n\n\"Phragma (=antecosta): dorsal thoracic transverse ridge, attachment site of dorsal longitudinal indirect flight muscles.\" (p. 121)"}
def: "The internal apodeme that is continuous with the cuticle of the notum and is attached to a dorsal longitudinal muscle." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000188 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! apodeme
is_a: UBERON:0000061 ! anatomical structure
relationship: attaches_to AISM:0002066 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! dorsal longitudinal thoracic muscle
relationship: continuous_with AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! notum
relationship: continuous_with UBERON:0001002 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cuticle

[Term]
id: AISM:0002049
name: postoccipital phragma {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x"}
def: "The phragma that is continuous with the postocciput." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002048 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phragma
relationship: continuous_with AISM:0004045 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postocciput

[Term]
id: AISM:0002050
name: postoccipitopremental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Postoccipital phragma, laterad to musculus\npostoccipitoparaglossalis\"\n\n\"Insertion: Posteriolateral angle of the prementum\""}
def: "The cranio-labial muscle that is attached to the postoccipital phragma and  the prementum." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000083 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle
relationship: attaches_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum
relationship: attaches_to AISM:0002049 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! postoccipital phragma

[Term]
id: AISM:0002051
name: tentorio-premental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Posterior tentorial arms, cranium\"\n\n\"Insertion: Laterobasal edge of prementum\""}
def: "The cranio-labial muscle that is attached to the posterior tentorial arm and the prementum." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000083 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle
relationship: attaches_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum
relationship: attaches_to AISM:0004037 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! posterior tentorial arm

[Term]
id: AISM:0002052
name: tentorio-paraglossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Posterior tentorial arms, postoccipital ridge or\ncranium\"\n\n\"Insertion: Paraglossa, close to the labial palp\""}
def: "The cranio-labial muscle that is attached to the posterior tentorial arm and the paraglossa." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000083 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle
relationship: attaches_to AISM:0000050 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! paraglossa
relationship: attaches_to AISM:0004037 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! posterior tentorial arm

[Term]
id: AISM:0002053
name: submentopremental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mediobasal part of submentum or gula\"\n\n\"Insertion: Mediobasal edge of prementum, close to the gales\""}
def: "The cranio-labial muscle that is attached to the submentum and the prementum." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000083 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle
relationship: attaches_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum
relationship: attaches_to AISM:0004005 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! submentum

[Term]
id: AISM:0002054
name: submentomental muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: submentum\"\n\n\"Insertion: mentum\""}
def: "The cranio-labial muscle that is attached to the submentum and the mentum." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000083 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle
relationship: attaches_to AISM:0004004 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect mentum
relationship: attaches_to AISM:0004005 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! submentum

[Term]
id: AISM:0002055
name: premento-paraglossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesal on the basal edge of the prementum\"\n\n\"Insertion: Dorsobasal edge of paraglossa\""}
def: "The cranio-labial muscle that is attached to the prementum and the paraglossa." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000083 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle
relationship: attaches_to AISM:0000050 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! paraglossa
relationship: attaches_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum

[Term]
id: AISM:0002056
name: premento-glossal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Mesally on the prementum\"\n\n\"Insertion: Mediobasal edge of glossa\""}
def: "The cranio-labial muscle that is attached to the prementum and the glossa." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000083 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle
relationship: attaches_to AISM:0000049 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! glossa
relationship: attaches_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum

[Term]
id: AISM:0002057
name: premento-palpal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: prementum\"\n\n\"Insertion: labial palpus\""}
def: "The cranio-labial muscle that is attached to the prementum and the labial palpus." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0000083 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-labial muscle
relationship: attaches_to AISM:0000024 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! labial palpus
relationship: attaches_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prementum

[Term]
id: AISM:0002058
name: cranio-hypopharyngeal muscle
def: "The somatic muscle that is attached to the head capsule and the hypopharynx." [] {creation_date="2021-04-04", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0000080 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranial muscle
relationship: attaches_to AISM:0000093 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! hypopharynx

[Term]
id: AISM:0002059
name: fronto-oral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Frons\"\n\n\"Insertion: Oral arms of the suspensorial sclerites\""}
def: "The cranio-hypopharyngeal muscle that is attached to the frons and  the suspensorium." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002058 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-hypopharyngeal muscle
relationship: attaches_to AISM:0002019 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! hypopharyngeal suspensorium
relationship: attaches_to AISM:0004020 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frons

[Term]
id: AISM:0002060
name: tentorio-oral muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Anterior tentorial arm, epistomal sulcus or\nfrons close to epistomal sulcus\"\n\n\"Insertion: Oral arms of the suspensorial sclerites, well\nseperated from above\""}
def: "The cranio-hypopharyngeal muscle that is attached to the anterior tentorial arm and the suspensorium." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002058 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cranio-hypopharyngeal muscle
relationship: attaches_to AISM:0002019 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! hypopharyngeal suspensorium
relationship: attaches_to AISM:0004038 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! anterior tentorial arm

[Term]
id: AISM:0002061
name: insect cranio-tentorial muscle
def: "The somatic muscle that is attached to the head capsule and the tentorium." [] {creation_date="2021-04-04", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", http://purl.org/dc/terms/modified="2021-12-13"} ! somatic muscle
relationship: attaches_to AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorium

[Term]
id: AISM:0002062
name: tentorio-frontal muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Laterad on the anterior corpotentorium\"\n\n\"Insertion: Frons\""}
def: "The insect cranio-antennal muscle that is attached to the tentorial bridge and the frons." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002061 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-tentorial muscle
relationship: attaches_to AISM:0004020 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! frons
relationship: attaches_to AISM:0004024 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorial bridge

[Term]
id: AISM:0002063
name: tentorio-tentorial muscle {AISM:0000171="Wipfler B, Machida R, Mueller B, Beutel RG (2011). On the head morphology of Grylloblattodea (Insecta) and the systematic position of the order, with a new nomenclature for the head muscles of Dicondylia. Systematic Entomology, 36(2), 241-266.\n\n https://doi.org/10.1111/j.1365-3113.2010.00556.x\n\n\"Origin: Ventrolaterad on the anterior corpotentorium\"\n\n\"Insertion: Mesad on the posterior tentorium\""}
def: "The insect cranio-antennal muscle that is attached to the tentorial bridge and the tentorium." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002061 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect cranio-tentorial muscle
relationship: attaches_to AISM:0004024 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! tentorial bridge

[Term]
id: AISM:0002064
name: insect leg muscle
def: "The somatic muscle that is part of the insect leg." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg

[Term]
id: AISM:0002065
name: insect thoracic muscle
def: "The somatic muscle that is part of the insect thorax." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2021-12-13"}
is_a: UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! somatic muscle
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax

[Term]
id: AISM:0002066
name: dorsal longitudinal thoracic muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"}
def: "The insect thoracic muscle that is not fan-shaped and runs along the dorsal region, parallel to the anterior-posterior axis." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle
relationship: parallel_to BSPO:0000013 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! anterior-posterior axis
relationship: part_of BSPO:0000079 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! dorsal region

[Term]
id: AISM:0002067
name: dorso-ventral thoracic muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"}
def: "The insect thoracic muscle that runs parallel to the dorsal-ventral axis." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle
relationship: parallel_to BSPO:0000016 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! dorsal-ventral axis

[Term]
id: AISM:0002068
name: tergo-pleural muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"}
def: "The insect thoracic muscle that extends between the notum (or tergum) and the pleura." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle
relationship: attaches_to AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum
relationship: continuous_with AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron

[Term]
id: AISM:0002069
name: sterno-pleural muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"}
def: "The insect thoracic muscle that extends between the sternum and the pleura." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle
relationship: attaches_to AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron
relationship: attaches_to AISM:0004130 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum

[Term]
id: AISM:0002070
name: ventral-longitudinal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"}
def: "The insect thoracic muscle that is not fan-shaped and runs along the ventral region, parallel to the anterior-posterior axis." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect thoracic muscle
relationship: parallel_to BSPO:0000013 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! anterior-posterior axis
relationship: part_of BSPO:0000084 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ventral region

[Term]
id: AISM:0002071
name: prophragma-occipital muscle {def="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: prophragma\"\n\"insertion: postocciput\""}
def: "The dorsal longitudinal thoracic muscle that is attached to the prophragma and the postocciput." [] {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", creation_date="2021-04-06"}
is_a: AISM:0002066 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle
relationship: attaches_to AISM:0002076 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prophragma
relationship: attaches_to AISM:0004045 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! postocciput

[Term]
id: AISM:0002072
name: pronoto-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: pronotum\"\n\n\"insertion: postocciput\""}
def: "The dorsal longitudinal thoracic muscle that is attached to the pronotum and the postocciput." [] {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", creation_date="2021-04-06"}
is_a: AISM:0002066 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle
relationship: attaches_to AISM:0000059 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! pronotum
relationship: attaches_to AISM:0004045 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! postocciput

[Term]
id: AISM:0002073
name: prophragma-cervical muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: prophragma\"\n\"insertion: cervical sclerite\""}
def: "The dorsal longitudinal thoracic muscle that is attached to the prophragma and the cervical sclerite." [] {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", creation_date="2021-04-06"}
is_a: AISM:0002066 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle
relationship: attaches_to AISM:0002076 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prophragma
relationship: attaches_to AISM:0004141 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cervical sclerite

[Term]
id: AISM:0002074
name: dorsal cervico-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: cervical sclerite\"\n\n\"insertion: postocciput\""}
def: "The dorsal longitudinal thoracic muscle that is attached to the cervical sclerite and the postocciput." [] {creation_date="2021-04-04", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002066 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle
relationship: attaches_to AISM:0004045 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! postocciput
relationship: attaches_to AISM:0004141 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! cervical sclerite

[Term]
id: AISM:0002075
name: pronoto-phragmal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"origin: pronotum\"\n\"insertion: prophragma\""}
def: "The dorsal longitudinal thoracic muscle that is attached to the pronotum and the prophragma." [] {creation_date="2021-04-04", http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"}
is_a: AISM:0002066 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle
relationship: attaches_to AISM:0000059 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! pronotum
relationship: attaches_to AISM:0002076 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prophragma

[Term]
id: AISM:0002076
name: prophragma
def: "The phragma of the mesonotum that attaches to muscles attached to the pronotum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002048 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! phragma
relationship: part_of AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! mesonotum

[Term]
id: AISM:0002078
name: anterior cervico-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsoventral muscle that arises from dorsolateral postocciput and inserts on anterior tip of first lateral cervical sclerite.\""}
def: "The dorsoventral thoracic muscle of the prothorax that is attached to the anterior margin of a cervical sclerite and the dorso-lateral region of the postocciput." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002067 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle
relationship: part_of AISM:0004125 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! prothorax

[Term]
id: AISM:0002079
name: anterior pronoto-cervical muscle {def="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsoventral muscle that arises from anterolateral pronotum and inserts on atypically on middle region of anterior propleural sclerite.\""}
def: "The dorsoventral thoracic muscle that extends between the antero-lateral region of the pronotum and the medial region of the propleuron." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002067 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle

[Term]
id: AISM:0002080
name: prophragma-tentorial muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"}
def: "The dorsoventral thoracic muscle that extends between the tentorium and the prophragma." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002067 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle
relationship: attaches_to AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium
relationship: attaches_to AISM:0002076 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prophragma

[Term]
id: AISM:0002081
name: profurca-prophragmal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsoventral muscle that arises from posterior face of proximal profurcal arm and inserts on lateral prophragma.\""}
def: "The dorsoventral thoracic muscle that extends between the profurca and the lateral region of the prophragma." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002067 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle
relationship: attaches_to AISM:0000143 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! profurca

[Term]
id: AISM:0002082
name: profurca-occipital muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"}
def: "The dorsoventral thoracic muscle that extends between the posterior region (occipital region) of the head capsule and the profurca." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002067 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle
relationship: attaches_to AISM:0000143 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! profurca

[Term]
id: AISM:0002083
name: prophragma-mesophragmal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003\n\n\"The dorsal longitudinal muscle that arises from median prophragma and inserts on median mesophragma.\""}
def: "The dorsal longitudinal thoracic muscle that extends between the medial region of the prophragma and the medial region of the mesophragma." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002066 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorsal longitudinal thoracic muscle

[Term]
id: AISM:0002084
name: profurca-mesonotal muscle {AISM:0000171="Friedrich, F., & Beutel, R. G. (2008). The thorax of Zorotypus (Hexapoda, Zoraptera) and a new nomenclature for the musculature of Neoptera. \nArthropod Structure & Development, 37(1), 29-54.\n\nhttps://doi.org/10.1016/j.asd.2007.04.003"}
def: "The dorsoventral thoracic muscle that extends between the profurca and the mesonotum." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002067 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! dorso-ventral thoracic muscle
relationship: attaches_to AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum
relationship: attaches_to AISM:0000143 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! profurca

[Term]
id: AISM:0002085
name: insect abdominal muscle
def: "The somatic muscle that is part of the insect abdomen." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932", http://purl.org/dc/terms/modified="2021-12-13"} ! somatic muscle
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0002086
name: lateral abdominal muscle {AISM:0000171="Klug, R., & Bradler, S. (2006). The pregenital abdominal musculature in phasmids and its implications for the basal phylogeny of Phasmatodea (Insecta: Polyneoptera). \nOrganisms Diversity & Evolution, 6(3), 171-184.\n\nhttps://doi.org/10.1016/j.ode.2005.08.004"}
def: "The insect abdominal muscle that runs along the lateral region, parallel to the dorsal-ventral axis." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002085 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect abdominal muscle
relationship: parallel_to BSPO:0000016 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! dorsal-ventral axis
relationship: part_of BSPO:0000082 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lateral region

[Term]
id: AISM:0002087
name: ventral longitudinal abdominal muscle {AISM:0000171="Klug, R., & Bradler, S. (2006). The pregenital abdominal musculature in phasmids and its implications for the basal phylogeny of Phasmatodea (Insecta: Polyneoptera). \nOrganisms Diversity & Evolution, 6(3), 171-184.\n\nhttps://doi.org/10.1016/j.ode.2005.08.004"}
def: "The insect abdominal muscle that runs along the ventral region, parallel to the anterior-posterior axis." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002085 {http://purl.org/dc/elements/1.1/contributor="lagonzalezmo https://orcid.org/0000-0002-9136-9932"} ! insect abdominal muscle
relationship: parallel_to BSPO:0000013 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis
relationship: part_of BSPO:0000084 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ventral region

[Term]
id: AISM:0002088
name: dorsal longitudinal abdominal muscle {AISM:0000171="Klug, R., & Bradler, S. (2006). The pregenital abdominal musculature in phasmids and its implications for the basal phylogeny of Phasmatodea (Insecta: Polyneoptera). \nOrganisms Diversity & Evolution, 6(3), 171-184.\n\nhttps://doi.org/10.1016/j.ode.2005.08.004"}
def: "The insect abdominal muscle that runs along the dorsal region, parallel to the anterior-posterior axis." [] {creation_date="2021-04-22", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002085 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdominal muscle
relationship: parallel_to BSPO:0000013 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis
relationship: part_of BSPO:0000079 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! dorsal region

[Term]
id: AISM:0004001
name: palpifer {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Palpifer: small separate element of stipes, bears the maxillary palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The sclerite of the insect maxilla that is attached to the cuticle of stipes by the stipito-palpiferal conjunctiva and to the cuticle of maxillary palpus by the palpifero-palpal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: adjacent_to AISM:0000051 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpus
relationship: adjacent_to AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes
relationship: continuous_with AISM:0004010 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipito-palpiferal conjunctiva
relationship: continuous_with AISM:0004012 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifero-palpal conjunctiva
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla
property_value: IAO:0000589 "cuticle of palpifer" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004002
name: mental-premental conjunctiva
def: "The conjunctiva of the labium that connects the mentum and the prementum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum
relationship: continuous_with AISM:0004004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium

[Term]
id: AISM:0004003
name: postmentum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postmentum: posterior main element of labium, posteriorly adjacent with foramen occipitale in hexapods without gula or hypostomal bridge; often separated into two sclerites, the anterior mentum and the posterior submentum.\""}
def: "The sclerite of the cuticle of labium that is cmposed of the submentum and the mentum, which are connected by the submental-mental conjunctiva" [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: has_part AISM:0004004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum
relationship: has_part AISM:0004005 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submentum
relationship: has_part AISM:0004013 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submental-mental conjunctiva
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium

[Term]
id: AISM:0004004
name: insect mentum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Mentum: intermediate part of labium, anterior part of postmentum; bears the prementum at its distal edge.\"", IAO:0000232="Modified 2023-01-20: to specify insect mentum.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The sclerite of the labium that is anterior to the submentum and posterior to the prementum, and attached to the prementum by the mental-premental conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: adjacent_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum
relationship: anterior_to AISM:0004005 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submentum
relationship: continuous_with AISM:0004002 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mental-premental conjunctiva
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium
relationship: posterior_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum

[Term]
id: AISM:0004005
name: submentum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Submentum: posterior part of a divided postmentum.\""}
def: "The sclerite of the labium that is anteriorly attached to the mentum by the submental-mental conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: continuous_with AISM:0004013 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submental-mental conjunctiva
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium
relationship: posterior_to AISM:0004004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum

[Term]
id: AISM:0004006
name: palpiger {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Palpiger: small separate element of prementum, bears the labial palp.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The sclerite of the cuticle of labium that is attached to the prementum by the premental-palpigeral conjunctiva and to the cuticle of labial palpus by the palpigero-palpal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-17"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: adjacent_to AISM:0000024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labial palpus
relationship: adjacent_to AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum
relationship: continuous_with AISM:0004014 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! premental-palpigeral conjunctiva
relationship: continuous_with AISM:0004017 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpigero-palpal conjunctiva
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium
property_value: IAO:0000589 "cuticle of palpiger" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004007
name: antenniferal-scapal conjunctiva
def: "The conjunctiva of the head capsule that connects the antennifer and the scapus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: AISM:0000078 AISM:0000113 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles scapus
relationship: continuous_with AISM:0000190 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antennifer
relationship: part_of AISM:0000112 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cranio-antennal conjunctiva

[Term]
id: AISM:0004008
name: interflagellomeral conjunctiva
def: "Is the conjunctiva of the antenna that connects a flagellomere and other flagellomere." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000102 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva
relationship: AISM:0000078 AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles flagellomere
relationship: AISM:0000079 AISM:0000116 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by flagellomere
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! antenna

[Term]
id: AISM:0004009
name: stipito-lacinial conjunctiva
def: "The conjunctiva of the insect maxilla that connects the stipes and the lacinia." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000026 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lacinia
relationship: continuous_with AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla

[Term]
id: AISM:0004010
name: stipito-palpiferal conjunctiva
def: "The conjunctiva of the insect maxilla that connects the stipes and the palpifer." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes
relationship: continuous_with AISM:0004001 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifer
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla

[Term]
id: AISM:0004011
name: stipito-galeal conjunctiva
def: "The conjunctiva of the insect maxilla that connects the stipes and the galea." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000023 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! galea
relationship: continuous_with AISM:0000111 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! stipes
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla

[Term]
id: AISM:0004012
name: palpifero-palpal conjunctiva
def: "The conjunctiva of the insect maxilla that connects the palpifer and the maxillary palpus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000051 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! maxillary palpus
relationship: continuous_with AISM:0004001 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpifer
relationship: part_of AISM:0000044 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect maxilla

[Term]
id: AISM:0004013
name: submental-mental conjunctiva
def: "The conjunctiva of the labium that connects the submentum and the mentum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mentum
relationship: continuous_with AISM:0004005 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submentum
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium

[Term]
id: AISM:0004014
name: premental-palpigeral conjunctiva
def: "The conjunctiva of the labium that connects the prementum and the palpiger." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum
relationship: continuous_with AISM:0004006 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpiger
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium

[Term]
id: AISM:0004015
name: premental-paraglossal conjunctiva
def: "The conjunctiva of the labium that connects the prementum and the paraglossa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000050 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraglossa
relationship: continuous_with AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium

[Term]
id: AISM:0004016
name: premental-glossal conjunctiva
def: "The conjunctiva of the labium that connects the prementum and the glossa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000049 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! glossa
relationship: continuous_with AISM:0000057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prementum
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium

[Term]
id: AISM:0004017
name: palpigero-palpal conjunctiva
def: "The conjunctiva of the labium that connects the palpiger and the labial palpus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labial palpus
relationship: continuous_with AISM:0004006 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! palpiger
relationship: part_of AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labium

[Term]
id: AISM:0004018
name: clypeo-labral conjunctiva
def: "The conjunctiva of the insect maxilla that connects the clypeus and the labrum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000042 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labrum
relationship: continuous_with AISM:0004019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus

[Term]
id: AISM:0004019
name: clypeus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Clypeus: anteroventral part of head capsule; primarily separated from frons by transverse frontoclypeal strengthening ridge between anterior tentorial pits; usually bearing the labrum at its distal margin.\""}
def: "The region of the head capsule that is anterior to the frons and is attached to the labrum by the clypeo-labral conjunctiva" [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: adjacent_to AISM:0000042 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labrum
relationship: anterior_to AISM:0004020 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frons
relationship: continuous_with AISM:0004018 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeo-labral conjunctiva
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule

[Term]
id: AISM:0004020
name: frons {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Frons: frontal part of head capsule, delimited by ecdysial lines (frontal sutures); often triangular and bearing unpaired (median) ocellus.\""}
def: "The region of cuticle of the head capsule that is located posterior to the clypeus and delimited by the frontal suture." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: continuous_with AISM:0004029 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frontal suture
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule
relationship: posterior_to AISM:0004019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus

[Term]
id: AISM:0004021
name: postoccipital ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postoccipital ridge: strengthening ridge enclosing the foramen occipitale dorsally and laterally; also serving as muscle attachment area.\""}
def: "The ridge along the dorsal and lateral regions of the head capsule that is adjacent to the foramen occipitale." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge
relationship: adjacent_to AISM:0004023 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale

[Term]
id: AISM:0004022
name: circumocular ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Circumocular ridge: internal ridge enclosing compound eye.\""}
def: "The ridge of the head capsule surrounding the eye cuticle." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-02-19"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge
relationship: AISM:0000078 AISM:0000088 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles eye cuticle
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule

[Term]
id: AISM:0004023
name: foramen occipitale {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Foramen occipitale (=foramen magnum): posterior opening of head capsule; divided by tentorial bridge into alaforamen and neuroforamen.\""}
def: "The foramen of the head capsule that connects with the neck membrane and is divided by the tentorial bridge into alaforamen and neuroforamen." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "occipital foramen" EXACT [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000197 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! arthropod foramen
relationship: adjacent_to AISM:0004024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorial bridge
relationship: continuous_with AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule
relationship: continuous_with AISM:0000098 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! neck membrane
relationship: has_part AISM:0004040 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! alaforamen
relationship: has_part AISM:0004041 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! neuroforamen

[Term]
id: AISM:0004024
name: tentorial bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tentorial bridge (=corpotentorium): transverse element connecting posterior tentorial arms, often plate-like.\""}
def: "The apophysis of the tentorium originating from each posterior tentorial arm." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "corpotentorium" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tentorial bridge (=corpotentorium): transverse element connecting posterior tentorial arms, often plate-like.\""}
is_a: AISM:0000138 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis
relationship: continuous_with AISM:0004037 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior tentorial arm
relationship: part_of AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium

[Term]
id: AISM:0004025
name: vertex {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Vertex: posterodorsal part of head capsule, usually medially divided by ecdysial line (coronal suture).\""}
def: "The dorsal region of the head capsule that surrounds the coronal suture, and is connected laterally to the genae." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: AISM:0000078 AISM:0004030 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles coronal suture

[Term]
id: AISM:0004026
name: gena {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gena: lateral region of head capsule; not separated from vertex by a ridge or suture.\""}
def: "The lateral region of the head capsule, connected dorsally to the lateral regions of the vertex." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle

[Term]
id: AISM:0004027
name: subgena {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subgena: narrow lateral region of head capsule, above external side of mandibular base, usually separated from gena by subgenal ridge.\""}
def: "The lateral region of the head capsule that connects dorsally to the ventral side of the gena and ventrally to the mandible." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: adjacent_to AISM:0000043 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect mandible

[Term]
id: AISM:0004028
name: cuticular suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Suture: ecdysial suture, zone of weakness.\"", http://purl.org/dc/terms/modified="2021-12-10"}
def: "The region of the cuticle of the head capsule that coincides with an ecdysial line." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule
relationship: RO:0002008 AISM:0004157 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with ecdysial line

[Term]
id: AISM:0004029
name: frontal suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Frontal suture: paired ecdysial sutures enclosing frons; anterior parts of epicranial suture.\""}
def: "The cuticular suture that surrounds the frons and is connected to the coronal suture." [] {creation_date="2021-04-03", http://purl.org/dc/terms/modified="2021-12-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004028 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular suture
relationship: AISM:0000078 AISM:0004020 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles frons
relationship: continuous_with AISM:0004030 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coronal suture
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired

[Term]
id: AISM:0004030
name: coronal suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coronal suture: unpaired median ecdysial sutures dividing vertex; anteriorly continuous with frontal sutures.\""}
def: "The longitudinal cuticular suture that is on the vertex and is connected to the frontal suture." [] {creation_date="2021-04-03", http://purl.org/dc/terms/modified="2021-12-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004028 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular suture
relationship: AISM:0000079 AISM:0004025 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by vertex
relationship: continuous_with AISM:0004029 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frontal suture
relationship: parallel_to BSPO:0000013 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior-posterior axis

[Term]
id: AISM:0004031
name: pleurostomal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n[Pleurostomal ridge: anterior section of the subgenal ridge above the mandibular base. (p. 14)]"}
def: "The ridge of the head capsule comprising the posterior region of the subgenal ridge." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge

[Term]
id: AISM:0004032
name: subgenal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subgenal ridge: strengthening ridge separating gena from subgena.\""}
def: "The ridge of the head capsule that separates the gena and the subgena." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge
relationship: adjacent_to AISM:0004026 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gena
relationship: adjacent_to AISM:0004027 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! subgena
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule

[Term]
id: AISM:0004033
name: hypostomal bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypostomal bridge: partial closure of foramen occipitale, formed by ventromedially adjacent extensions of lateral head capsule.\"\n[posterior section of the subgenal ridge; p. 14]"}
def: "The lateral region of the head capsule that is adjacent to the foramen occipitale" [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: adjacent_to AISM:0004023 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule

[Term]
id: AISM:0004034
name: frontoclypeal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Frontoclypeal (strengthening) ridge (=frontoclypeal “suture”, epistomal “suture”): internal ridge separating clypeus from frons, between anterior tentorial pits.\""}
def: "The ridge of the head capsule that separates the clypeus and the frons." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge
relationship: adjacent_to AISM:0004019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus
relationship: adjacent_to AISM:0004020 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frons
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule

[Term]
id: AISM:0004035
name: gula {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gula: sclerite partially closing foramen occipitale, formed by sclerotized region of ventral cervical membrane.\""}
def: "The sclerite on the ventral region of the head capsule that is limited laterally by the gular ridges, posteriorly by the foramen occipitale and anteriorly by the submentum." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: anterior_to AISM:0004023 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale
relationship: continuous_with AISM:0004036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gular ridge
relationship: posterior_to AISM:0004005 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! submentum

[Term]
id: AISM:0004036
name: gular ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gular ridges: lateral internal ridges enclosing the gula.\""}
def: "Each ridge on the ventral region of the head capsule marking the sides of the gula." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge

[Term]
id: AISM:0004037
name: posterior tentorial arm {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Posterior tentorial arm: paired posterior element of tentorium; originates at posterior tentorial pit.\""}
def: "The apophysis of the tentorium that originates from each posterior tentorial pit." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000138 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis
relationship: continuous_with AISM:0000195 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! posterior tentorial pit
relationship: part_of AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium

[Term]
id: AISM:0004038
name: anterior tentorial arm {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anterior tentorial arm: paired tentorial element anterior to tentorial bridge; originates at anterior tentorial pit.\""}
def: "The apophysis of the tentorium that is connected to an anterior tentorial pit." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000138 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis
relationship: continuous_with AISM:0000194 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior tentorial pit
relationship: part_of AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium

[Term]
id: AISM:0004039
name: dorsal tentorial arm {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Dorsal tentorial arm: paired dorsal element of tentorium, originating at anterior arm or connecting area of anterior and posterior arm; often connected with head capsule by fibrillae.\""}
def: "The apophysis of the tentorium that is connected to an anterior tentorial arm." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000138 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis
relationship: continuous_with AISM:0004038 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior tentorial arm
relationship: part_of AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium

[Term]
id: AISM:0004040
name: alaforamen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter. \n\nhttps://doi.org/10.1515/9783110264043\n\n\"Alaforamen: part of foramen occipitale above tentorial bridge; passage of oesophagus and tracheal stems.\""}
def: "The arthropod foramen that is part of the foramen occipitale and is located above the tentorial bridge." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000197 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! arthropod foramen
relationship: dorsal_to AISM:0004024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorial bridge
relationship: part_of AISM:0004023 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale

[Term]
id: AISM:0004041
name: neuroforamen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Neuroforamen: part of foramen occipitale below tentorial bridge; passage of cervical connectives between suboesophageal complex and prothoracic ganglion.\""}
def: "The arthropod foramen that is part of the foramen occipitale and located below the tentorial bridge." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000197 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! arthropod foramen
relationship: part_of AISM:0004023 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale
relationship: ventral_to AISM:0004024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorial bridge

[Term]
id: AISM:0004042
name: postgena {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postgena: posterior genal region anterior to postoccipital ridge.\""}
def: "The posterior region of the head capsule that is continuous with the posterior region of the gena and is anterior to the postoccipital ridge." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle

[Term]
id: AISM:0004043
name: postgenal bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postgenal bridge: partial closure of foramen occipital formed by postgenal extensions.\""}
def: "The region of the head capsule that is continuous with the postgena and adjacent to the foramen occipitale." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: adjacent_to AISM:0004023 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! foramen occipitale
relationship: continuous_with AISM:0004042 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postgena
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule

[Term]
id: AISM:0004044
name: circumantennal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The antennal foramen is enclosed by a circumantennal ridge, which often bears a small articulatory process, the antennifer.\""}
def: "The ridge of the head capsule that encircles the antennal foramen." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge
relationship: AISM:0000078 AISM:0000198 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles antennal foramen
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! head capsule

[Term]
id: AISM:0004045
name: postocciput {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postocciput: posteriormost head region.\""}
def: "The dorsolateral region of the head capsule that is posterior to the postoccipital ridge" [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/terms/modified="2022-06-17"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: posterior_to AISM:0004021 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! postoccipital ridge

[Term]
id: AISM:0004046
name: hypostoma {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypostoma: posterior part of subgena.\""}
def: "The region of the head capsule that comprises the posterior region of the subgena." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle

[Term]
id: AISM:0004047
name: hypostomal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Hypostomal ridge: posterior part of subgenal ridge.\""}
def: "The ridge composing the posterior region of the subgenal ridge." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge

[Term]
id: AISM:0004048
name: occipital ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Occipital ridge (=“occipital suture”): ridge on posterior head region; present in some groups, oblique and short or more or less parallel to postocciptal rigde (Orthoptera). No true segmental border.\""}
def: "The ridge that runs along the posterior region of the head capsule." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "occipital suture" EXACT [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge
is_a: BSPO:0000077 ! proximal region

[Term]
id: AISM:0004049
name: postclypeus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postclypeus: sclerotized and pigmented proximal part of clypeus.\""}
def: "The region of cuticle comprising the posterior region of the clypeus." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle

[Term]
id: AISM:0004050
name: anteclypeus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anteclypeus: transparent distal part of clypeus.\""}
def: "The region of the cuticle comprising the anterior region of the clypeus." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle

[Term]
id: AISM:0004051
name: clypeolabrum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Clypeolabrum: area comprising the fused clypeus and labrum.\""}
def: "The region of the cuticle that is composed of the clypeus and the labrum." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_part AISM:0000042 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labrum
relationship: has_part AISM:0004019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus

[Term]
id: AISM:0004052
name: insect compound eye {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Compound eye: paired main light sense organs; almost always composed of numerous ommatidia.\"", IAO:0000232="Modified 2023-01-09: specifying insect compound eye.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The sense organ of the insect head that is covered by the eye cuticle." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000018 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! compound eye
relationship: has_part AISM:0000088 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! eye cuticle
relationship: part_of AISM:0000107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head

[Term]
id: AISM:0004053
name: insect ocellus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ocellus: relatively simple median eye with single cornea lens and always lacking a crystalline cone: three are probably present in the groundplan of Insecta, but reductions occur in many groups.\"", IAO:0000232="Modified 2023-01-09: specifying insect ocellus.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The sense organ of the insect head that is covered by eye cuticle." [] {creation_date="2021-04-03", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000020 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sense organ
relationship: has_part AISM:0000088 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! eye cuticle
relationship: part_of AISM:0000107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect head

[Term]
id: AISM:0004054
name: laminatentoria {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"In some groups an accessory bridge is formed by medially fused internally directed processes, the laminatentoria. This feature is sometimes erroneously referred to as “perforated corpotentorium”.\""}
def: "Are apophyses of the tentorium originating at each anterior tentorial arm." [] {creation_date="2021-02-24", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000138 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular apophysis
relationship: continuous_with AISM:0004038 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anterior tentorial arm
relationship: part_of AISM:0000191 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tentorium

[Term]
id: AISM:0004055
name: preabdomen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Preabdomen (=pregenital segments): anterior abdominal segments (I–VII).\""}
def: "The region of cuticle of the insect abdomen that is posteriorly connected to the postabdomen." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen
relationship: posteriorly_connected_to AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004056
name: postabdomen {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postabdomen: posterior segments (VIII–XI) bearing genital appendages.\""}
def: "The region of cuticle of the insect abdomen that is anteriorly connected to the preabdomen." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: anteriorly_connected_to AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004057
name: abdominal tergite {AISM:0000171="Lawrence J, Ślipiński A (2013) 1 Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 520 pp. \n\nhttps://www.publish.csiro.au/book/6466/\n\n\"major plate of the abdominal tergum\""}
def: "The sclerite of the insect abdomen that is dorsal and medial." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
synonym: "abdominal tergum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tergum: plate-like dorsal sclerite of abdominal segment.\""}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect sclerite
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect abdomen
relationship: part_of BSPO:0000079 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! dorsal region
relationship: part_of BSPO:0000083 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! medial region

[Term]
id: AISM:0004058
name: abdominal sternite
def: "The sclerite of the insect abdomen that is ventral and medial." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
synonym: "abdominal sternum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sternum: plate-like ventral sclerite of abdominal segment.\""}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen
relationship: part_of BSPO:0000083 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! medial region
relationship: part_of BSPO:0000084 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ventral region

[Term]
id: AISM:0004059
name: pleural membrane {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleural membrane: lateral unsclerotized part of abdominal segments, connecting tergum and sternum; usually bearing spiracles I–VIII.\""}
def: "The conjunctiva of the insect abdomen that surrounds the spiracles." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: AISM:0000078 AISM:0000135 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles insect spiracle
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004060
name: epiproct {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epiproct: unpaired dorsal element (tergum) of segment XI.\""}
def: "The sclerite of the postabdomen that is attached to the posterior margin of the abdominal tergite X by the abdominal tergite X-epiproct conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
synonym: "proctiger" EXACT [] {AISM:0000171="Lawrence J, Ślipiński A (2013) 1 Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 520 pp. \n\nhttps://www.publish.csiro.au/book/6466/\n\n[not defined]"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: continuous_with AISM:0004120 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! abdominal tergite X-epiproct conjunctiva
relationship: continuous_with AISM:0004197 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect anus
relationship: dorsal_to AISM:0004197 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect anus
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004061
name: paraproct {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraproct: paired lateral element of segment XI.\""}
def: "The paired sclerite of the insect abdomen that is attached to the lateral margin of the abdominal tergite X by the abdominal tergite X-paraproct conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: adjacent_to AISM:0004197 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect anus
relationship: continuous_with AISM:0004167 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite X-paraproct conjunctiva
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004062
name: aedeagus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Aedeagus (penis is often used as a synonym): male copulatory organ.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticular evagination of the postabdomen that is distal and attached to the cuticle of parameres by the paramero-aedeagal conjunctiva and is connected to the endophallus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
synonym: "insect penis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Penis: main element of the male copulatory apparatus.\""}
is_a: AISM:0000027 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination
relationship: adjacent_to AISM:0004064 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramere
relationship: continuous_with AISM:0004063 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! endophallus
relationship: continuous_with AISM:0004200 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramero-aedeagal conjunctiva
relationship: distal_to AISM:0004064 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! paramere
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen
property_value: IAO:0000589 "cuticle of aedeagus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004063
name: endophallus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Endophallus: membranous extrusible internal part of aedeagus.\""}
def: "The cuticular invagination of the postabdomen that is attached distally to the gonopore and basally to the aedeagus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
is_a: AISM:0000006 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular invagination
relationship: adjacent_to AISM:0004062 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! aedeagus
relationship: adjacent_to AISM:0004075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonopore
relationship: distal_to AISM:0004075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonopore
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen
relationship: proximal_to AISM:0004062 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! aedeagus

[Term]
id: AISM:0004064
name: paramere {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Parameres: paired lateral parts of aedeagus.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the paired cuticular evagination of the postabdomen that is attached to the cuticle of phallobase by the phallobasal-parameral conjunctiva and to the cuticle of aedeagus by the paramero-aedeagal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
is_a: AISM:0000027 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular evagination
relationship: adjacent_to AISM:0004062 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! aedeagus
relationship: continuous_with AISM:0004200 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramero-aedeagal conjunctiva
relationship: continuous_with AISM:0004201 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phallobasal-parameral conjunctiva
relationship: distal_to AISM:0004065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! phallobase
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen
property_value: IAO:0000589 "cuticle of paramere" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004065
name: phallobase {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Phallobase (=basal piece): part of segment IX bearing copulatory organ.\""}
def: "The region of cuticle of the postabdomen that is attached to the abdominal sternite IX by the abdominal sternite IX-phallobase conjunctiva and to the paramere by the phallobasal-parameral conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
synonym: "basal piece" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Phallobase (=basal piece): part of segment IX bearing copulatory organ.\""}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: adjacent_to AISM:0004064 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramere
relationship: adjacent_to AISM:0004119 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IX
relationship: continuous_with AISM:0004124 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IX-phallobase conjunctiva
relationship: continuous_with AISM:0004201 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phallobasal-parameral conjunctiva
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004066
name: endophallite {AISM:0000171="Génier F (2019) Endophallites: a proposed neologism for naming the sclerotized elements of the insect endophallus (Arthropoda: Insecta). Annales de la Société entomologique de France (N.S.) 55: 482–484. \n\nhttps://doi.org/10.1080/00379271.2019.1685907 \n\n\"endophallite(s) refer to the sclerotized structures of the endophallus whether the structure be circular, flat, folded or spiniform.\""}
def: "The region of cuticle of the endophallus that is thicker." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_characteristic PATO:0000591 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! increased thickness
relationship: part_of AISM:0004063 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! endophallus

[Term]
id: AISM:0004067
name: bursa copulatrix {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Bursa copulatrix: evagination of the vagina, receives the copulatory organ.\""}
def: "The region of the cuticle in the postabdomen that is attached to the genital chamber." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: continuous_with AISM:0004069 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! genital chamber
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004068
name: gonocoxa VIII {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The paired sclerite of the postabdomen that is attached to the abdominal sternite VII by the abdominal sternite VII-gonocoxa conjunctiva and is articulated with abdominal tergite IX. It is attached at the base of gonostylus VIII and adjacent to the gonopore." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
synonym: "first coxopodite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""}
synonym: "first gonocoxite" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""}
synonym: "first valvifer" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""}
is_a: AISM:0004301 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxite
relationship: adjacent_to AISM:0004075 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! gonopore
relationship: continuous_with AISM:0004084 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII-gonocoxa VIII conjunctiva
property_value: IAO:0000589 "cuticle of gonocoxa VIII" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004069
name: genital chamber {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Genital chamber: cavity formed by an inflection of the body wall, receiving the common oviduct.\""}
def: "The region of cuticle that is connected to the oviduct, the bursa copulatrix and the gonocoxa VIII, and is adjacent to the gonopore." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: adjacent_to AISM:0004075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonopore
relationship: continuous_with AISM:0004067 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bursa copulatrix
relationship: continuous_with AISM:0004068 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxa VIII
relationship: continuous_with AISM:0004083 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect oviduct

[Term]
id: AISM:0004070
name: gonapophysis {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gonapophysis (=valves or valvulae 1–3): distal piece of ovipositor elements of female genital segments VIII and IX, inserted on coxopodites, usually elongated.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the abdominal sternite VIII that is part of the ovipositor." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000029 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect appendage
relationship: part_of AISM:0004077 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ovipositor
relationship: part_of AISM:0004110 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII
property_value: IAO:0000589 "cuticle of gonapophysis" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004071
name: sensillum placodeum {IAO:0000232="Modified 2023-01-11: moved under cuticular sensilla; added has part cuticular seta.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensillum placodeum: flat sensillum with strongly modified plate-like seta.\""}
def: "The seta that is flattened." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0004304 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular sensilla
relationship: has_characteristic PATO:0000407 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! flat
relationship: has_part AISM:0000039 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular seta

[Term]
id: AISM:0004072
name: trichobothrium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trichobothrium: very long and fine sensillum, vibroreceptor.\""}
def: "The seta that is elongated." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000039 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular seta
relationship: has_characteristic PATO:0001154 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! elongated

[Term]
id: AISM:0004073
name: paraphyses {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraphyses (=titillators): paired appendages of aedeagus.\""}
def: "The proximal apodemes of the aedeagus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
synonym: "titillators" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paraphyses (=titillators): paired appendages of aedeagus.\""}
is_a: AISM:0000188 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! apodeme
relationship: proximal_to AISM:0004062 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! aedeagus

[Term]
id: AISM:0004074
name: ductus ejaculatorius {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ductus ejaculatorius: unpaired ectodermal duct connecting vasa deferentia (i.e. vesiculae seminales) and aedeagus.\""}
def: "The region of the cuticle thar is proximally attached to the gonopore." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: adjacent_to AISM:0004075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonopore
relationship: proximal_to AISM:0004075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonopore

[Term]
id: AISM:0004075
name: gonopore {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gonopore: external opening of the common oviduct.\"", creation_date="2021-03-05"}
def: "The orifice in the postabdomen that marks the opening of the reproductive system." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: UBERON:0000161 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! orifice
relationship: AISM:0000079 AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by postabdomen

[Term]
id: AISM:0004076
name: gonostylus VIII {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Gonostyli: appendages of gonocoxae (usually only on coxopodite IX)\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The region of the cuticle of the postabdomen that is paired and connected to the anterior region of the gonocoxa VIII." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen
property_value: IAO:0000589 "cuticle of gonostylus VIII" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004077
name: ovipositor {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ovipositor: paired postabdominal apparatus (segments VIII and IX) primarily used for depositing eggs.\""}
def: "The region of cuticle of the postabdomen that is distal to the genital chamber." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: distal_to AISM:0004069 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! genital chamber
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004078
name: spermatheca {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spermatheca (=receptaculum seminis): unpaired or paired evagination of female genital tract; storage of sperm; connected by spermathecal duct (=ductus receptaculi) with vagina or bursa copulatrix.\""}
def: "The region of the cuticle that is part of the oviduct and connected to the bursa copulatrix." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: continuous_with AISM:0004067 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bursa copulatrix
relationship: part_of AISM:0004083 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect oviduct

[Term]
id: AISM:0004079
name: spermathecal gland {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spermathecal gland: provides nourishment for spermatozoa stored in spermatheca.\""}
def: "The region of the cuticle that is part of the oviduct and attached to the spermatheca." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: continuous_with AISM:0004078 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! spermatheca
relationship: part_of AISM:0004083 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect oviduct

[Term]
id: AISM:0004080
name: precoxal sulcus
def: "The sulcus that coincides with the precoxal ridge." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
synonym: "precoxal suture" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Precoxal suture: suture separating katepisternum and preepisternum.\""}
is_a: AISM:0000162 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular sulcus
relationship: RO:0002008 AISM:0004162 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with precoxal ridge

[Term]
id: AISM:0004081
name: pleural wing process {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Fulcrum (=pleural wing process): anterodorsal apex of the pleural ridge.\""}
def: "The cuticular protrusion of the pleuron that is connected lateraly to the notum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
synonym: "fulcrum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Fulcrum (=pleural wing process): anterodorsal apex of the pleural ridge.\""}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular protrusion
relationship: AISM:0000011 AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! lateral_to notum
relationship: part_of AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron

[Term]
id: AISM:0004082
name: metanoto-abdominal tergite I conjunctiva
def: "The conjunctiva between the insect thorax and the insect abdomen that connects the posterior margin of the metanotum to the anterior margin of the abdominal tergite I." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000021 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I
relationship: continuous_with AISM:0000169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum

[Term]
id: AISM:0004083
name: insect oviduct {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Oviduct: female genital duct; originating as paired structures from ovarioles, uniting as common (median) oviduct.\""}
def: "The region of cuticle that is continuous with the genital chamber." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
is_a: UBERON:0000993 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! oviduct
relationship: continuous_with AISM:0004069 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! genital chamber

[Term]
id: AISM:0004084
name: abdominal sternite VIII-gonocoxa VIII conjunctiva
def: "The conjunctiva of the insect abdomen that joins the abdominal sternite VIII and the gonocoxa VIII." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-01-09: correct sternite VII to VIII.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004068 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gonocoxa VIII
relationship: continuous_with AISM:0004110 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004085
name: abdominal tergite II
def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite I by the abdominal tergite I-abdominal tergite II conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite
relationship: anteriorly_connected_to AISM:0004086 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I-abdominal tergite II conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004086
name: abdominal tergite I-abdominal tergite II conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal tergite I and the abdominal tergite II." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000021 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I
relationship: continuous_with AISM:0004085 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite II
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004087
name: abdominal tergite III
def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite II by the abdominal tergite II-abdominal tergite III conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite
relationship: anteriorly_connected_to AISM:0004088 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite II-abdominal tergite III conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004088
name: abdominal tergite II-abdominal tergite III conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal tergite II and the abdominal tergite III." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004085 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite II
relationship: continuous_with AISM:0004087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite III
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004089
name: abdominal tergite III-abdominal tergite IV conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal tergite III and the abdominal tergite IV." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite III
relationship: continuous_with AISM:0004090 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IV
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004090
name: abdominal tergite IV
def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite III by the abdominal tergite III-abdominal tergite IV conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite
relationship: anteriorly_connected_to AISM:0004089 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite III-abdominal tergite IV conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004091
name: abdominal tergite V
def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite IV by the abdominal tergite IV-abdominal tergite V conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite
relationship: anteriorly_connected_to AISM:0004092 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IV-abdominal tergite V conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004092
name: abdominal tergite IV-abdominal tergite V conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal tergite IV and the abdominal tergite V." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004090 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IV
relationship: continuous_with AISM:0004091 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite V
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004093
name: abdominal tergite VI
def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite V by the abdominal tergite V-abdominal tergite VI conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite
relationship: anteriorly_connected_to AISM:0004094 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite V-abdominal tergite VI conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004094
name: abdominal tergite V-abdominal tergite VI conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal tergite V and the abdominal tergite VI." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004091 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite V
relationship: continuous_with AISM:0004093 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VI
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004095
name: abdominal tergite VII
def: "Is the abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal tergite VI by the abdominal tergite VI-abdominal tergite VII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite
relationship: anteriorly_connected_to AISM:0004096 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VI-abdominal tergite VII conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004096
name: abdominal tergite VI-abdominal tergite VII conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal tergite VI and the abdominal tergite VII." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004093 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VI
relationship: continuous_with AISM:0004095 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VII
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004097
name: abdominal tergite VIII
def: "Is the abdominal tergite of the postabdomen that is attached to the posterior margin of the abdominal tergite VII by the abdominal tergite VII-abdominal tergite VIII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite
relationship: anteriorly_connected_to AISM:0004098 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VII-abdominal tergite VIII conjunctiva
relationship: part_of AISM:0000523 ! dorsal postabdomen

[Term]
id: AISM:0004098
name: abdominal tergite VII-abdominal tergite VIII conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal tergite VII and the abdominal tergite VIII." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004095 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VII
relationship: continuous_with AISM:0004097 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VIII
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004099
name: laterotergite {AISM:0000171="Lawrence J, Ślipiński A (2013) 1 Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 520 pp. \n\nhttps://www.publish.csiro.au/book/6466/\n\nadditional pair of sclerites flanking each tergite"}
name: laterotergite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Laterotergite: separate lateral portion of abdominal tergum (only few groups).\""}
def: "The sclerite of the insect thorax or the insect abdomen that is on the lateral region of the notum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
synonym: "paranota" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Paranota (=laterotergites): dorsolateral tergal duplicatures.\""}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004100
name: abdominal sternite I
def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the metasternum by the metasterno-abdominal sternite I conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004058 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite
relationship: anteriorly_connected_to AISM:0004102 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metasterno-abdominal sternite I conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004101
name: metapleuro-metasternal conjunctiva
def: "The conjunctiva of the metathorax that joins the metapleura and the metasternum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000119 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuron
relationship: continuous_with AISM:0004232 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metasternum
relationship: part_of AISM:0004127 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax

[Term]
id: AISM:0004102
name: metasterno-abdominal sternite I conjunctiva
def: "The conjunctiva between the insect thorax and the insect abdomen that connects the posterior margin of the metasterum to the anterior margin of the abdominal sternite I." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004100 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite I
relationship: continuous_with AISM:0004101 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuro-metasternal conjunctiva

[Term]
id: AISM:0004103
name: abdominal sternite I-abdominal sternite II conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal sternite I and the abdominal sternite II." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004100 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite I
relationship: continuous_with AISM:0004104 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite II
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004104
name: abdominal sternite II
def: "The abdominal tergite of the preabdomen that is attached to the posterior margin of the abdominal sternite I by the abdominal sternite I-abdominal sternite II conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004058 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite
relationship: anteriorly_connected_to AISM:0004103 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite I-abdominal sternite II conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004105
name: abdominal sternite III
def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite II by the abdominal sternite II-abdominal sternite III conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004058 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite
relationship: anteriorly_connected_to AISM:0004111 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite II-abdominal sternite III conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004106
name: abdominal sternite IV
def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite III by the abdominal sternite III-abdominal sternite IV conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004058 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite
relationship: anteriorly_connected_to AISM:0004112 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite III-abdominal sternite IV conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004107
name: abdominal sternite V
def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite IV by the abdominal sternite IV-abdominal sternite V conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004058 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite
relationship: anteriorly_connected_to AISM:0004113 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IV-abdominal sternite V conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004108
name: abdominal sternite VI
def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite V by the abdominal sternite V-abdominal sternite VI conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004058 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite
relationship: anteriorly_connected_to AISM:0004114 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite V-abdominal sternite VI conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004109
name: abdominal sternite VII
def: "The abdominal sternite of the preabdomen that is attached to the posterior margin of the abdominal sternite VI by the abdominal sternite VI-abdominal sternite VII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004058 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite
relationship: anteriorly_connected_to AISM:0004115 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VI-abdominal sternite VII conjunctiva
relationship: part_of AISM:0004055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! preabdomen

[Term]
id: AISM:0004110
name: abdominal sternite VIII
def: "The abdominal sternite of the postabdomen that is attached to the posterior margin of the abdominal sternite VII by the abdominal sternite VII-abdominal sternite VIII conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004058 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen
relationship: posteriorly_connected_to AISM:0004123 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII-abdominal sternite IX conjunctiva

[Term]
id: AISM:0004111
name: abdominal sternite II-abdominal sternite III conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal sternite II and the abdominal sternite III." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004104 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite II
relationship: continuous_with AISM:0004105 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite III
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004112
name: abdominal sternite III-abdominal sternite IV conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal sternite III and the abdominal sternite IV." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004105 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite III
relationship: continuous_with AISM:0004106 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IV
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004113
name: abdominal sternite IV-abdominal sternite V conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal sternite IV and the abdominal sternite V." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004106 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IV
relationship: continuous_with AISM:0004107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite V
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004114
name: abdominal sternite V-abdominal sternite VI conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal sternite V and the abdominal sternite VI." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite V
relationship: continuous_with AISM:0004108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VI
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004115
name: abdominal sternite VI-abdominal sternite VII conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal sternite VI and the abdominal sternite VII." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VI
relationship: continuous_with AISM:0004109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VII
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004116
name: abdominal sternite VII-abdominal sternite VIII conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal sternite VII and the abdominal sternite VIII." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VII
relationship: continuous_with AISM:0004110 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004117
name: abdominal tergite IX
def: "Is the abdominal tergite of the postabdomen that is attached to the posterior margin of the abdominal tergite VIII by the abdominal tergite VIII-abdominal tergite IX conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite
relationship: anteriorly_connected_to AISM:0004121 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VIII-abdominal tergite IX conjunctiva
relationship: part_of AISM:0000523 ! dorsal postabdomen

[Term]
id: AISM:0004118
name: abdominal tergite X
def: "Is the abdominal tergite of the postabdomen that is attached to the posterior margin of the abdominal tergite IX by the abdominal tergite IX-abdominal tergite X conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004057 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite
relationship: anteriorly_connected_to AISM:0004122 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX-abdominal tergite X conjunctiva
relationship: part_of AISM:0000523 ! dorsal postabdomen

[Term]
id: AISM:0004119
name: abdominal sternite IX
def: "The abdominal sternite of the postabdomen that is attached to the posterior margin of the abdominal sternite VIII by the abdominal sternite VIII-abdominal sternite IX conjunctiva." [] {creation_date="2021-03-14", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004058 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite
relationship: anteriorly_connected_to AISM:0004116 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VII-abdominal sternite VIII conjunctiva
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004120
name: abdominal tergite X-epiproct conjunctiva
def: "The conjunctiva of the postabdomen that joins the abdominal tergite X and the epiproct." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004060 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epiproct
relationship: continuous_with AISM:0004118 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite X
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004121
name: abdominal tergite VIII-abdominal tergite IX conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal tergite VIII and the abdominal tergite IX." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004097 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite VIII
relationship: continuous_with AISM:0004117 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004122
name: abdominal tergite IX-abdominal tergite X conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal tergite IX and the abdominal tergite X." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004117 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite IX
relationship: continuous_with AISM:0004118 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite X
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004123
name: abdominal sternite VIII-abdominal sternite IX conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal sternite VIII and the abdominal sternite IX." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004110 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite VIII
relationship: continuous_with AISM:0004119 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IX
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004124
name: abdominal sternite IX-phallobase conjunctiva
def: "The conjunctiva of the insect abdomen that connects the abdominal sternite IX and the abdominal sternite X." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004065 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phallobase
relationship: continuous_with AISM:0004119 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal sternite IX
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect abdomen

[Term]
id: AISM:0004125
name: prothorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prothorax: 1st thoracic segment, always completely wingless in extant hexapods.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The region of the cuticle of the insect thorax that is anteriorly connected to the head by the neck membrane, posteriorly connected to the mesothorax by the prothorax-mesothorax conjunctiva, and contains the pronotum, the propeluron, the prosternum and one pair of legs." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: anteriorly_connected_to AISM:0000098 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! neck membrane
relationship: has_part AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg
relationship: has_part AISM:0000059 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum
relationship: has_part AISM:0000060 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! labial palpomere
relationship: has_part AISM:0000061 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prosternum
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax
relationship: posteriorly_connected_to AISM:0000046 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothoracic-mesothoracic conjunctiva
property_value: IAO:0000589 "cuticle of prothorax" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004126
name: mesothorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Mesothorax: 2nd thoracic segment, anterior segment of pterothorax; bearing forewings (groundplan of Pterygota).\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The region of the cuticle of the pterothorax that bears mid legs and fore wings." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_part AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg
relationship: has_part AISM:0000037 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore wing
relationship: part_of AISM:0004166 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pterothorax
property_value: IAO:0000589 "cuticle of mesothorax" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004127
name: metathorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Metathorax: 3rd thoracic segment, posterior segment of pterothorax; bearing hindwings (groundplan of Pterygota).\"", http://purl.org/dc/terms/modified="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The region of the cuticle of the pterothorax that bears the hind legs and the hind wings." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_part AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg
relationship: has_part AISM:0000038 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind wing
relationship: part_of AISM:0004166 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pterothorax
property_value: IAO:0000589 "cuticle of metathorax" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004128
name: notum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Notum: larger anterior part of tergum, composed of presutum, scutum and scutellum.\""}
def: "The dorsal region of the cuticle of the insect thorax that is attached to the dorsal margin of the pleuron." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
synonym: "tergum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tergum: dorsal wall of a thoracic (or abdominal) segment.\""}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle

[Term]
id: AISM:0004129
name: pleuron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleuron: lateral wall of thoracic segments, almost always divided by pleural ridge into anterior episternum and posterior epimeron.\""}
def: "The region of cuticle on the lateral region of the insect thorax that is attached to the notum and the sternum and is attached to the coxae by skeletal muscle tissue and the basal coxal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
is_a: UBERON:0000061 ! anatomical structure
relationship: adjacent_to AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum
relationship: adjacent_to AISM:0004130 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum
relationship: continuous_with AISM:0000173 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! basal coxal conjunctiva

[Term]
id: AISM:0004130
name: sternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sternum: ventral wall of thoracic (or abdominal) segment, usually divided into presternum, basisternum, furcasternum and spinasternum in unspecialized hexapods; largely or completely invaginated in Holometabola (cryptosterny).\""}
def: "The ventral region of the cuticle of the insect thorax that is attached to the ventral margin of the pleuron." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle

[Term]
id: AISM:0004131
name: pleurite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleurite: sclerotized element of pleuron.\""}
def: "The sclerite that is part of the pleuron." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: part_of AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron

[Term]
id: AISM:0004132
name: pleural ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pleural ridge: internal ridge, corresponding to externally visible pleural “suture”; separates episternum and epimeron; anterodorsally forming the pleural wing process and posteroventrally the pleuro-coxal joint.\""}
def: "The ridge between the epimeron and the episternum in either the mesothorax or the metathorax." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge
relationship: continuous_with AISM:0004133 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! episternum
relationship: continuous_with AISM:0004134 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epimeron

[Term]
id: AISM:0004133
name: episternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Episternum: part of pleuron anterior to pleural ridge.\""}
def: "The sclerite of the insect thorax that is part of the pleuron and anterior to the pleural ridge and attached to the anterior margin of the epimeron." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: anterior_to AISM:0004132 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleural ridge
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron

[Term]
id: AISM:0004134
name: epimeron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epimeron: part of pleuron posterior to pleural ridge.\""}
def: "The sclerite of the insect thorax that is part of the pleuron and posterior to the pleural ridge and attached to the posterior margin of the episternum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron
relationship: posterior_to AISM:0004132 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleural ridge

[Term]
id: AISM:0004135
name: trochantin {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trochantin: small triangular or sickle-shaped ventral pleural sclerite; anteriorly articulating with coxa (trochantino-coxal joint).\""}
def: "The sclerite that is located on the ventro-lateral region of the insect thorax and is attached to a coxa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: adjacent_to AISM:0000077 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa
relationship: AISM:0000079 AISM:0000173 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by basal coxal conjunctiva

[Term]
id: AISM:0004136
name: presternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Presternum: anteriormost part of sternum.\""}
def: "The part of the sternum that is attached to the anterior margin of the basisternum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0004130 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum

[Term]
id: AISM:0004137
name: basisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Basisternum: main part of sternum, between presternum and furcasternum.\""}
def: "The part of the sternum that is attached to the posterior margin of the presternum and to the anterior margin of the furcasternum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0004130 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum

[Term]
id: AISM:0004138
name: furcasternum {http://purl.org/dc/elements/1.1/contributor="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furcasternum (=sternellum): sternal element posterior to basisternum, area of origin of furca.\""}
def: "The part of the sternum that is attached to the posterior margin of the basisternum and to the anterior margin of the spinasternum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
synonym: "sternellum" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Furcasternum (=sternellum): sternal element posterior to basisternum, area of origin of furca.\""}
is_a: AISM:0004130 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum

[Term]
id: AISM:0004139
name: spinasternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spinasternum: small posterior sternal element, determining the posterior segmental border; area of origin of spina.\""}
def: "The part of the sternum that is attached to the posterior margin of the furcasternum and to the anterior margin of the poststernite." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0004130 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum

[Term]
id: AISM:0004140
name: poststernite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Poststernite: posteriormost sternal element.\""}
def: "The part of the sternum that is attached to the posterior margin of the spinasternum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0004130 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum

[Term]
id: AISM:0004141
name: cervical sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cervical sclerite: articulatory sclerite embedded in the cervical membrane.\""}
def: "The sclerite that is surrounded by the neck membrane." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: AISM:0000079 AISM:0000098 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by neck membrane

[Term]
id: AISM:0004142
name: propleuron
def: "The region of the cuticle on the lateral region of the prothorax that is attached to the pronotum and the prosternum, and is attached to the procoxa by the procoxal muscle and the basal procoxal conjunctiva." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron
relationship: adjacent_to AISM:0000059 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum
relationship: adjacent_to AISM:0000061 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prosternum
relationship: continuous_with AISM:0000106 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! basal procoxal conjunctiva
relationship: continuous_with AISM:0000145 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! procoxal muscle

[Term]
id: AISM:0004143
name: postnotum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postnotum: smaller posterior part of tergum, forming internal intersegmental phragma; attachment area for dorsal indirect flight muscles.\""}
def: "The sclerite of the notum that is attached to the posterior margin of the scutellum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: part_of AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum

[Term]
id: AISM:0004144
name: prescutum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prescutum: anteriormost part of notum.\""}
def: "The sclerite of the notum that is attached to the anterior margin of the scutum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: part_of AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum

[Term]
id: AISM:0004145
name: scutum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Scutum: large anterior part of notum.\""}
def: "The sclerite of the notum that is attached to the posterior margin of the prescutum and to the anterior margin of the scutellum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: part_of AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum

[Term]
id: AISM:0004146
name: scutellum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Scutellum: smaller posterior part of notum.\""}
def: "The sclerite of the notum that is attached to the posterior margin of the scutum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: part_of AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum

[Term]
id: AISM:0004147
name: alinotum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Alinotum: part of the notum connected with the wing base.\""}
def: "The sclerite that is on the lateral region of the notum and is adjacent to the wing." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: adjacent_to AISM:0000033 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing

[Term]
id: AISM:0004148
name: prealar sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prealare (=prealar sclerite): small attachment area of short direct flight muscles.\""}
def: "The sclerite of the pterothorax that is attached to some muscle." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "prealare" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prealare (=prealar sclerite): small attachment area of short direct flight muscles.\""}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: continuous_with UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! somatic muscle
relationship: part_of AISM:0004166 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pterothorax

[Term]
id: AISM:0004149
name: prealar bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Prealar bridge: prescutal process, bent downwards and linked with episternum.\""}
def: "The region of cuticle of the dorso-lateral region of the pterothorax that is surrounded by the noto-pleural conjunctiva and articulated with the episternum." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: adjacent_to AISM:0004133 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! episternum
relationship: continuous_with AISM:0004222 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! noto-pleural conjunctiva

[Term]
id: AISM:0004150
name: postalar bridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postalar bridge: lateral postnotal margin bent downwards and connected with the epimeron.\""}
def: "The region of cuticle of the dorso-lateral region of the pterothorax that is surrounded by the noto-pleural conjunctiva and articulated with the epimeron." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: adjacent_to AISM:0004134 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epimeron
relationship: continuous_with AISM:0004222 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! noto-pleural conjunctiva

[Term]
id: AISM:0004151
name: epipleurite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Epipleurites: basalare and subalare.\""}
def: "The sclerite of the insect thorax that is surrounded by the noto-pleural conjunctiva and is adjacent to the wing." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: adjacent_to AISM:0000033 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing
relationship: AISM:0000079 AISM:0004080 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by precoxal sulcus
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax

[Term]
id: AISM:0004152
name: basalare {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Basalare: sclerite associated with wing base, more or less distinctly separated from anepisternum; usually with internal muscle disc; attachment site of direct flight muscles.\""}
def: "The epipleurite that is adjacent to the anepisternum, is attached to the pleuron via muscle, is surrounded by the noto-pleural conjunctiva, and is anterior to the first axillary sclerite." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004151 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epipleurite
is_a: UBERON:0000061 ! anatomical structure
relationship: adjacent_to AISM:0004154 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anepisternum
relationship: AISM:0000079 AISM:0004222 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by noto-pleural conjunctiva
relationship: anterior_to AISM:0000022 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! first axillary sclerite

[Term]
id: AISM:0004153
name: subalare {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subalare: sclerite associated with wing base, usually embedded in membrane between tergum and pleuron; attachment site of direct flight muscles.\""}
def: "The epipleurite that is adjacent to the notum, is attached to the coxa via muscle, is surrounded by the noto-pleural conjunctiva, and is posterior to the first axillary sclerite." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004151 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epipleurite
is_a: UBERON:0000061 ! anatomical structure
relationship: adjacent_to AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum
relationship: AISM:0000079 AISM:0004222 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by noto-pleural conjunctiva
relationship: posterior_to AISM:0000022 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! first axillary sclerite

[Term]
id: AISM:0004154
name: anepisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anepisternum: dorsal part of episternum, ventrally delimited by anapleural suture.\""}
def: "The dorsal region of the episternum that is dorsal to the anapleural sulcus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: dorsal_to AISM:0004156 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anapleural sulcus
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired

[Term]
id: AISM:0004155
name: preepisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Preepisternum: anterior part of ventral episternal region; delimited from katepisternum by precoxal suture; largest part of ventrite in Holometabola.\""}
def: "The region of cuticle on the antero-ventral region of the episternum that is anterior to the anapleural sulcus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: anterior_to AISM:0004156 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anapleural sulcus

[Term]
id: AISM:0004156
name: anapleural sulcus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anapleural suture (=paracoxal suture): suture horizontally delimiting dorsal and ventral parts of episternum and (partially) epimeron; sometimes anteriorly widened and membranous (=anapleural cleft).\""}
def: "The sulcus of the pleuron delimiting the dorsal region of the preepisternum and the ventral region of the anepisternum." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "anapleural cleft" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anapleural suture (=paracoxal suture): suture horizontally delimiting dorsal and ventral parts of episternum and (partially) epimeron; sometimes anteriorly widened and membranous (=anapleural cleft).\""}
synonym: "paracoxal suture" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anapleural suture (=paracoxal suture): suture horizontally delimiting dorsal and ventral parts of episternum and (partially) epimeron; sometimes anteriorly widened and membranous (=anapleural cleft).\""}
is_a: AISM:0000162 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular sulcus
relationship: part_of AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron

[Term]
id: AISM:0004157
name: ecdysial line
def: "The anatomical line of weakness of the cuticle that allows molting and coincides with a suture." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "molting line" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Molting lines (frontal and coronal sutures [=epicranial lines or sutures])\""}
is_a: CARO:0000008 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anatomical line
relationship: RO:0002008 AISM:0004028 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with cuticular suture

[Term]
id: AISM:0004158
name: katepisternum {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Katepisternum: posterior part of ventral episternal region; separated from preepisternum by precoxal suture.\""}
def: "The region of cuticle on the postero-ventral region of the episternum that is posterior to the anapleural sulcus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: posterior_to AISM:0004156 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anapleural sulcus

[Term]
id: AISM:0004159
name: anepimeron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anepimeron: dorsal part of epimeron (present as separate element in some groups).\""}
def: "The region of the cuticle on the dorsal region of the epimeron." [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired

[Term]
id: AISM:0004160
name: katepimeron {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Katepimeron: ventral part of epimeron (present as separate element in some groups).\""}
def: "The region of cuticle on the ventral region of the epimeron." [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle

[Term]
id: AISM:0004161
name: axillary sclerite {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Axillary sclerites (=axillaria, pteralia): small sclerites of wing base (usually 3); articulating with notal wing processes.\""}
def: "The sclerite that is surrounded by the basal wing conjunctiva." [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "pteralia" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pteralia: small sclerites of wing base (axillary sclerites + plates).\""}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: AISM:0000079 AISM:0004203 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircled by basal wing conjunctiva
relationship: part_of AISM:0004258 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! axillary region of the insect wing

[Term]
id: AISM:0004162
name: precoxal ridge {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Precoxal ridge: mediolaterally directed ridge in front of coxa, corresponding with externally visible precoxal suture.\""}
def: "The ridge that is anterior to a coxa, demarcated by the anapleural sulcus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000158 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular ridge
relationship: anterior_to AISM:0000077 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa
relationship: continuous_with AISM:0004156 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! anapleural sulcus

[Term]
id: AISM:0004163
name: spina {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Spina: smaller posterior endoskeletal element of thoracic segments, unpaired, arising on spinasternum.\""}
def: "The sclerite attached to the spinasternum." [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: continuous_with AISM:0004139 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! spinasternum

[Term]
id: AISM:0004165
name: cercus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cerci: tactile appendages of segment XI, primarily multisegmented and tactile bearing setae.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The bilaterally paired region of the cuticle of the postabdomen located between the epiproct and the paraproct" [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
intersection_of: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! insect region of cuticle
intersection_of: adjacent_to AISM:0004060 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! epiproct
intersection_of: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! bilaterally paired
intersection_of: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-08-01"} ! postabdomen
relationship: adjacent_to AISM:0004060 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epiproct
relationship: adjacent_to AISM:0004061 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraproct
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen
property_value: IAO:0000589 "cuticle of cercus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004166
name: pterothorax {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pterothorax: 2nd and 3nd thoracic segments; bearing wings (groundplan of Pterygota), meso- and metathorax.\""}
def: "The region of cuticle of the insect thorax that contains the mesothorax and the metathorax and bears the mid legs, the hind legs and the wings." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-05"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_part AISM:0004126 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax
relationship: has_part AISM:0004127 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metathorax
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax

[Term]
id: AISM:0004167
name: abdominal tergite X-paraproct conjunctiva
def: "The conjunctiva of the postabdomen that joins the abdominal tergite X and each paraproct." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004061 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraproct
relationship: continuous_with AISM:0004118 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite X
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004168
name: trochanter {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Trochanter: 2nd element of leg, usually small and triangular.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a leg attached to the distal margin of the coxa by the coxal-trochanteral conjunctiva and to the proximal margin of the femur by the trochantero-femoral conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000063 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment
relationship: AISM:0000078 AISM:0004174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles trochantero-femoral conjunctiva
relationship: AISM:0000079 AISM:0004170 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by coxal-trochanteral conjunctiva
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg
property_value: IAO:0000589 "cuticle of trochanter" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004169
name: tarsus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Tarsus: 5th part of leg; undivided in entognathous orders, composed of 3–5 tarsomeres in most groups of Insecta.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of the leg that is composed of tarsomeres connected to each other by intertarsomeral conjunctiva. The first tarsomere is connected to the distal margin of the tibia by the tibio-tarsal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000063 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! appendage segment
relationship: AISM:0000079 AISM:0004182 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tibio-tarsal conjunctiva
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: has_part AISM:0000074 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsomere
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg
property_value: IAO:0000589 "cuticle of tarsus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004170
name: coxal-trochanteral conjunctiva
def: "The conjunctiva of the leg joining the distal margin of a coxa and the proximal margin of a femur." [] {creation_date="2021-03-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000102 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! ring conjunctiva
relationship: AISM:0000078 AISM:0004168 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles trochanter
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg

[Term]
id: AISM:0004171
name: protrochanter {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a fore leg attached to the distal margin of the procoxa by the procoxal-protrochanteral conjunctiva and to the proximal margin of the profemur by the protrochantero-profemoral conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0004168 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter
relationship: AISM:0000078 AISM:0004175 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles protrochantero-profemoral conjunctiva
relationship: AISM:0000079 AISM:0000123 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by procoxal-protrochanteral conjunctiva
relationship: part_of AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg
property_value: IAO:0000589 "cuticle of protrochanter" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004172
name: mesotrochanter {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a mid leg attached to the distal margin of the mesocoxa by the mesocoxal-mesotrochanteral conjunctiva and to the proximal margin of the mesofemur by the mesotrochantero-mesofemoral conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0004168 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter
relationship: AISM:0000078 AISM:0004176 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesotrochantero-mesofemoral conjunctiva
relationship: AISM:0000079 AISM:0000124 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesocoxal-mesotrochanteral conjunctiva
relationship: part_of AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg
property_value: IAO:0000589 "cuticle of mesotrochanter" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004173
name: metatrochanter {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of a hind leg attached to the distal margin of the metacoxa by the metacoxal-metatrochanteral conjunctiva and to the proximal margin of the metafemur by the metatrochantero-metafemoral conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0004168 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter
relationship: AISM:0000078 AISM:0004177 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metatrochantero-metafemoral conjunctiva
relationship: AISM:0000079 AISM:0000125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metacoxal-metatrochanteral conjunctiva
relationship: part_of AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg
property_value: IAO:0000589 "cuticle of metatrochanter" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004174
name: trochantero-femoral conjunctiva
def: "The conjunctiva that encircles the femur by joining the distal margin of the trochanter and the proximal margin of the femur." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-18"}
is_a: AISM:0000102 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva
relationship: AISM:0000078 AISM:0000076 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles femur
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg

[Term]
id: AISM:0004175
name: protrochantero-profemoral conjunctiva
def: "The conjunctiva that encircles the profemur by joining the distal margin of the protrochanter and the proximal margin of the profemur." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantero-femoral conjunctiva
relationship: AISM:0000078 AISM:0000070 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles profemur
relationship: part_of AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg

[Term]
id: AISM:0004176
name: mesotrochantero-mesofemoral conjunctiva
def: "The conjunctiva that encircles the mesofemur by joining the distal margin of the mesotrochanter and the proximal margin of the mesofemur." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantero-femoral conjunctiva
relationship: AISM:0000078 AISM:0000071 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesofemur
relationship: part_of AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg

[Term]
id: AISM:0004177
name: metatrochantero-metafemoral conjunctiva
def: "The conjunctiva that encircles the metafemur by joining the distal margin of the metatrochanter and the proximal margin of the metafemur." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantero-femoral conjunctiva
relationship: AISM:0000078 AISM:0000072 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metafemur
relationship: part_of AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg

[Term]
id: AISM:0004178
name: femoro-tibial conjunctiva
def: "The conjunctiva that encircles the tibia by joining the distal margin of the femur and the proximal margin of the tibia." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0000102 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva
relationship: AISM:0000078 AISM:0000075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles tibia
relationship: AISM:0000079 AISM:0000076 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by femur
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg

[Term]
id: AISM:0004179
name: profemoro-protibial conjunctiva
def: "The conjunctiva that encircles the protibia by joining the distal margin of the profemur and the proximal margin of the protibia." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004178 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femoro-tibial conjunctiva
relationship: AISM:0000078 AISM:0000067 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles protibia
relationship: AISM:0000079 AISM:0000070 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by profemur
relationship: part_of AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg

[Term]
id: AISM:0004180
name: mesofemoro-mesotibial conjunctiva
def: "The conjunctiva that encircles the mesotibia by joining the distal margin of the mesofemur and the proximal margin of the mesotibia." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004178 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femoro-tibial conjunctiva
relationship: AISM:0000078 AISM:0000068 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesotibia
relationship: AISM:0000079 AISM:0000071 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesofemur
relationship: part_of AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg

[Term]
id: AISM:0004181
name: metafemoro-metatibial conjunctiva
def: "The conjunctiva that encircles the metatibia by joining the distal margin of the metafemur and the proximal margin of the metatibia." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004178 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! femoro-tibial conjunctiva
relationship: AISM:0000078 AISM:0000069 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metatibia
relationship: AISM:0000079 AISM:0000072 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metafemur
relationship: part_of AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg

[Term]
id: AISM:0004182
name: tibio-tarsal conjunctiva
def: "The conjunctiva that encircles the tarsus by joining the distal margin of the tibia and the proximal margin of the tarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0000102 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva
relationship: AISM:0000078 AISM:0004169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles tarsus
relationship: AISM:0000079 AISM:0000075 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tibia
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg

[Term]
id: AISM:0004183
name: protibio-protarsal conjunctiva
def: "The conjunctiva that encircles the protarsus by joining the distal margin of the protibia and the proximal margin of the protarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004182 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibio-tarsal conjunctiva
relationship: AISM:0000078 AISM:0004190 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles protarsus
relationship: AISM:0000079 AISM:0000067 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by protibia
relationship: part_of AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg

[Term]
id: AISM:0004184
name: mesotibio-mesotarsal conjunctiva
def: "The conjunctiva that encircles the mesotarsus by joining the distal margin of the mesotibia and the proximal margin of the mesotarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004182 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibio-tarsal conjunctiva

[Term]
id: AISM:0004185
name: metatibio-metatarsal conjunctiva
def: "The conjunctiva that encircles the metatarsus by joining the distal margin of the metatibia and the proximal margin of the metatarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004182 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tibio-tarsal conjunctiva
relationship: AISM:0000078 AISM:0004188 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metatarsus
relationship: AISM:0000079 AISM:0000069 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metatibia
relationship: part_of AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg

[Term]
id: AISM:0004186
name: mesopleuron
def: "The region of the cuticle on the lateral region of the mesothorax that is attached to the mesonotum and the mesosternum, and is attached to the mesocoxa by the mesocoxal muscle and the basal mesocoxal conjunctiva." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron
relationship: adjacent_to AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum
relationship: adjacent_to AISM:0000121 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesosternum
relationship: continuous_with AISM:0000085 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesocoxal muscle
relationship: continuous_with AISM:0000103 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! basal mesocoxal conjunctiva

[Term]
id: AISM:0004187
name: tarso-pretarsal conjunctiva
def: "The conjunctiva that encircles the pretarsus by joining the distal margin of the distalmost tarsomere and the proximal margin of the pretarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0000102 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ring conjunctiva
relationship: AISM:0000078 AISM:0000047 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles pretarsus
relationship: AISM:0000079 AISM:0004169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by tarsus
relationship: part_of AISM:0000031 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect leg

[Term]
id: AISM:0004188
name: metatarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of the leg that is composed of metatarsomeres connected to each other by intertarsomeral conjunctiva. The first metatarsomere is connected to the distal margin of the metatibia by the metatibio-metatarsal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus
relationship: AISM:0000079 AISM:0004185 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metatibio-metatarsal conjunctiva
relationship: part_of AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg
property_value: IAO:0000589 "cuticle of metatarsus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004189
name: mesotarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of the mid leg that is composed of mesotarsomeres connected to each other by intertarsomeral conjunctiva. The first mesotarsomere is connected to the distal margin of the mesotibia by the mesotibio-mesotarsal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus
relationship: AISM:0000079 AISM:0004184 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesotibio-mesotarsal conjunctiva
property_value: IAO:0000589 "cuticle of mesotarsus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004190
name: protarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the segment of the leg that is composed of protarsomeres connected to each other by intertarsomeral conjunctiva. The first protarsomere is connected to the distal margin of the protibia by the protibio-protarsal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-08", IAO:0000232="Modified 2023-04-13: removed distally adjacent elements to avoid problems with their absence during presence/absence reasoning.\njgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarsus
relationship: AISM:0000079 AISM:0004183 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by protibio-protarsal conjunctiva
relationship: part_of AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg
property_value: IAO:0000589 "cuticle of protarsus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004191
name: protarso-propretarsal conjunctiva
def: "The conjunctiva that encircles the propretarsus by joining the distal margin of the distalmost protarsomere and the proximal margin of the propretarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004187 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-pretarsal conjunctiva
relationship: AISM:0000078 AISM:0004194 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles propretarsus
relationship: AISM:0000079 AISM:0004190 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by protarsus

[Term]
id: AISM:0004192
name: mesotarso-mesopretarsal conjunctiva
def: "The conjunctiva that encircles the mesopretarsus by joining the distal margin of the distalmost mesotarsomere and the proximal margin of the mesopretarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004187 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-pretarsal conjunctiva
relationship: AISM:0000078 AISM:0004195 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles mesopretarsus
relationship: AISM:0000079 AISM:0004189 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by mesotarsus

[Term]
id: AISM:0004193
name: metatarso-metapretarsal conjunctiva
def: "The conjunctiva that encircles the metapretarsus by joining the distal margin of the distalmost metatarsomere and the proximal margin of the metapretarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0004187 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tarso-pretarsal conjunctiva
relationship: AISM:0000078 AISM:0004196 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircles metapretarsus
relationship: AISM:0000079 AISM:0004188 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by metatarsus

[Term]
id: AISM:0004194
name: propretarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the fore leg that is attached to the protarsus by the protarso-propretarsal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0000047 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus
relationship: continuous_with AISM:0004191 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! protarso-propretarsal conjunctiva
relationship: part_of AISM:0000034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! fore leg
property_value: IAO:0000589 "cuticle of propretarsus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004195
name: mesopretarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the mid leg that is attached to the mesotarsus by the mesotarso-mesopretarsal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0000047 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus
relationship: continuous_with AISM:0004192 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesotarso-mesopretarsal conjunctiva
relationship: part_of AISM:0000035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mid leg
property_value: IAO:0000589 "cuticle of mesopretarsus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004196
name: metapretarsus {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the appendage of the hind leg that is attached to the metatarsus by the metatarso-metapretarsal conjunctiva." [] {http://purl.org/dc/terms/modified="2021-12-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0000047 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus
relationship: continuous_with AISM:0004193 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metatarso-metapretarsal conjunctiva
relationship: part_of AISM:0000036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! hind leg
property_value: IAO:0000589 "cuticle of metapretarsus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004197
name: insect anus
def: "The orifice on the postabdomen at the posterior margin of the digestive tract, connected to the epiproct and paraprocti." [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: UBERON:0000161 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! orifice
relationship: adjacent_to AISM:0004060 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! epiproct
relationship: adjacent_to AISM:0004061 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paraproct
relationship: AISM:0000079 AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! encircled by postabdomen

[Term]
id: AISM:0004198
name: gonostylus IX {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The region of the cuticle of the postabdomen that is paired and connected to the anterior region of the gonocoxa IX." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen
property_value: IAO:0000589 "cuticle of gonostylus IX" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004199
name: cercomere {IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of the mere that is part of the cercus." [] {http://purl.org/dc/terms/modified="2021-12-08", creation_date="2021-08-04", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000073 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mere
relationship: part_of AISM:0004165 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cercus
property_value: IAO:0000589 "cuticle of cercomere" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004200
name: paramero-aedeagal conjunctiva
def: "The conjunctiva of the postabdomen that joins the parameres and the aedeagus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004062 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! aedeagus
relationship: continuous_with AISM:0004064 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramere
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004201
name: phallobasal-parameral conjunctiva
def: "The conjunctiva of the postabdomen that joins the phallobase and the parameres." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-03-28"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0004064 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! paramere
relationship: continuous_with AISM:0004065 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! phallobase
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen

[Term]
id: AISM:0004202
name: propleuro-prosternal conjunctiva
def: "The conjunctiva of the prothorax that joins the propleura and the prosternum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000061 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prosternum
relationship: continuous_with AISM:0004142 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! propleuron
relationship: part_of AISM:0004125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax

[Term]
id: AISM:0004203
name: basal wing conjunctiva
def: "The conjunctiva of the pterothorax that surrounds the wing." [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: AISM:0000078 AISM:0000033 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! encircles insect wing
relationship: part_of AISM:0004166 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pterothorax

[Term]
id: AISM:0004204
name: tergo-trochantinal muscle
def: "The insect thoracic muscle that attaches to the notum and to the trochantin." [] {creation_date="2021-04-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle
relationship: attaches_to AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum
relationship: attaches_to AISM:0004135 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochantin
property_value: curator_notes "For muscular terminology, tergum has been traditionally used instead of notum, even though \"notum\" is the prererred term to refer to the dorsal region of the cuticle of the insect thorax that is attached to the dorsal margin of the pleuron." xsd:string {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}

[Term]
id: AISM:0004205
name: pronoto-protrochantinal muscle
def: "The tergo-trochantinal muscle that is attached to the pronotum and the protrochantin." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004204 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tergo-trochantinal muscle
relationship: attaches_to AISM:0000055 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! protrochantin
relationship: attaches_to AISM:0000059 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum

[Term]
id: AISM:0004206
name: mesonoto-mesotrochantinal muscle
def: "The tergo-trochantinal muscle that is attached to the mesonotum and the mesotrochantin." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004204 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-trochantinal muscle
relationship: attaches_to AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum
relationship: attaches_to AISM:0000054 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesotrochantin

[Term]
id: AISM:0004207
name: metanoto-metatrochantinal muscle
def: "The tergo-trochantinal muscle that is attached to the metanotum and the metatrochantin." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004204 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! tergo-trochantinal muscle
relationship: attaches_to AISM:0000056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metatrochantin
relationship: attaches_to AISM:0000169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum

[Term]
id: AISM:0004208
name: tergo-tergal muscle
def: "The insect thoracic muscle that extends between two nota (or terga)." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle
relationship: attaches_to AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum

[Term]
id: AISM:0004209
name: pronoto-mesonotal muscle
def: "The insect thoracic muscle that extends between the pronotum and the mesonotum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004208 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-tergal muscle
relationship: attaches_to AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum
relationship: attaches_to AISM:0000059 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum

[Term]
id: AISM:0004210
name: mesonoto-metanotal muscle
def: "The insect thoracic muscle that extends between the mesonotum and the metanotum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004208 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-tergal muscle
relationship: attaches_to AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum
relationship: attaches_to AISM:0000169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum

[Term]
id: AISM:0004211
name: tergo-coxal muscle
def: "The insect thoracic muscle that extends between the notum (or tergum) and the coxa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle
relationship: attaches_to AISM:0000077 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa
relationship: attaches_to AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum

[Term]
id: AISM:0004212
name: tergo-trochanteral muscle
def: "The insect thoracic muscle that extends between the notum (or tergum) and the trochanter." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle
relationship: attaches_to AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum
relationship: attaches_to AISM:0004168 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter

[Term]
id: AISM:0004213
name: pleuro-coxal muscle
def: "The insect thoracic muscle that attaches to the pleuron and to a coxa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle
relationship: attaches_to AISM:0000077 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa
relationship: attaches_to AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron

[Term]
id: AISM:0004214
name: furco-coxal muscle
def: "The insect thoracic muscle that is attached to a furca and to a coxa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-08"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle
relationship: attaches_to AISM:0000077 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coxa
relationship: attaches_to AISM:0000144 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! furca

[Term]
id: AISM:0004215
name: furco-trochanteral muscle
def: "The insect thoracic muscle that is attached to a furca and to a trochanter." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-08"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle
relationship: attaches_to AISM:0000144 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! furca
relationship: attaches_to AISM:0004168 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! trochanter

[Term]
id: AISM:0004216
name: interfurcal muscle
def: "The insect thoracic muscle that extends between two furcae." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle
relationship: attaches_to AISM:0000144 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! furca

[Term]
id: AISM:0004217
name: profurco-mesofurcal muscle
def: "The insect thoracic muscle that extends between the profurca and the mesofurca." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004216 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! interfurcal muscle
relationship: attaches_to AISM:0000141 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesofurca
relationship: attaches_to AISM:0000143 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! profurca

[Term]
id: AISM:0004218
name: mesofurco-metafurcal muscle
def: "The insect thoracic muscle that extends between the mesofurca and the metafurca." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004216 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! interfurcal muscle
relationship: attaches_to AISM:0000141 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesofurca
relationship: attaches_to AISM:0000142 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metafurca

[Term]
id: AISM:0004219
name: mesonoto-mesopleural conjuntiva
def: "The noto-pleural conjunctiva that joins the mesonotum and the mesopleuron." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004222 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! noto-pleural conjunctiva
relationship: continuous_with AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum
relationship: continuous_with AISM:0004186 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopleuron

[Term]
id: AISM:0004220
name: pronoto-propleural conjunctiva
def: "The noto-pleural conjunctiva that joins the pronotum and the propleuron." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004222 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! noto-pleural conjunctiva
relationship: continuous_with AISM:0000059 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pronotum
relationship: continuous_with AISM:0004142 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! propleuron

[Term]
id: AISM:0004221
name: metanoto-metapleural conjunctiva
def: "The noto-pleural conjunctiva that joins the metanotum and the metapleuron." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004222 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! noto-pleural conjunctiva
relationship: continuous_with AISM:0000119 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuron
relationship: continuous_with AISM:0000169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum

[Term]
id: AISM:0004222
name: noto-pleural conjunctiva
def: "The conjunctiva of the insect thorax that joins the notum and the pleuron." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0004128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! notum
relationship: continuous_with AISM:0004129 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pleuron
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax

[Term]
id: AISM:0004223
name: third axillary sclerite
def: "The axillary sclerite that is connected via muscle to the mesopleuron and is  posterior to the first axillary sclerite." [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004161 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite
relationship: posterior_to AISM:0000022 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! first axillary sclerite

[Term]
id: AISM:0004224
name: ventral second axillary sclerite
def: "The axillary sclerite that is on the ventral region of the basal wing conjunctiva." [] {creation_date="2021-04-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004161 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! axillary sclerite

[Term]
id: AISM:0004225
name: mesophragma
def: "The phragma of the metanotum that attaches to muscles attached to the mesonotum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002048 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! phragma
relationship: part_of AISM:0000169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum

[Term]
id: AISM:0004226
name: mesophragmo-abdominal tergite I muscle
def: "The insect thoracic muscle that extends between the mesophragma and the abdominal tergite I." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004208 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! tergo-tergal muscle
relationship: attaches_to AISM:0000021 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I
relationship: attaches_to AISM:0004225 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesophragma

[Term]
id: AISM:0004227
name: metafurco-abdominal sternite muscle
def: "The insect thoracic muscle that extends between the metafurca and an abdominal sternite." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002065 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! insect thoracic muscle
relationship: attaches_to AISM:0000142 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! metafurca
relationship: attaches_to AISM:0004058 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! abdominal sternite

[Term]
id: AISM:0004228
name: metaphragma
def: "The phragma of the abdominal tergite I that attaches to muscles attached to the metanotum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0002048 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! phragma
relationship: part_of AISM:0000021 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! abdominal tergite I

[Term]
id: AISM:0004229
name: mesonoto-metanotal conjunctiva
def: "The conjunctiva of the insect thorax that joins the mesonotum and the metanotum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000052 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesonotum
relationship: continuous_with AISM:0000169 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metanotum
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect thorax

[Term]
id: AISM:0004230
name: mesopleuro-mesocoxal conjunctiva
def: "The conjunctiva of the mesothorax that joins the mesopleuron and the mesocoxa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000064 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesocoxa
relationship: continuous_with AISM:0004186 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopleuron
relationship: part_of AISM:0004126 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax

[Term]
id: AISM:0004231
name: mesopleuro-mesosternal conjunctiva
def: "The conjunctiva of the mesothorax that joins the mesopleura and the mesosternum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! conjunctiva
relationship: continuous_with AISM:0000061 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prosternum
relationship: continuous_with AISM:0004186 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesopleuron
relationship: part_of AISM:0004125 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! prothorax

[Term]
id: AISM:0004232
name: metasternum
def: "The sclerite on the ventral region of the metathorax that bears the metafurca and is attached to the metapleuro-metasternal conjunctiva." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0004130 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! sternum
relationship: continuous_with AISM:0004101 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metapleuro-metasternal conjunctiva
relationship: has_part AISM:0000142 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! metafurca

[Term]
id: AISM:0004233
name: mesosterno-mesocoxal conjunctiva
def: "The conjunctiva of the mesothorax that joins the mesosternum and the mesocoxa." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-04-09"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! conjunctiva
relationship: continuous_with AISM:0000064 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesocoxa
relationship: continuous_with AISM:0000121 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesosternum
relationship: part_of AISM:0004126 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! mesothorax

[Term]
id: AISM:0004234
name: circular pouch {creation_date="2021-07-21"}
def: "The pouch that is circular." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-07-21"}
is_a: AISM:0000160 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! cuticular pouch
relationship: has_characteristic PATO:0000411 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! circular

[Term]
id: AISM:0004235
name: ectodermal gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"cells or groups of cells with highly specialized secretory functions, producing a great variety of substances which are discharged at the exterior or into invaginations of the body wall\""}
def: "The region of cuticle that is continuous with glandular epithelial cells." [] {creation_date="2021-08-17", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: continuous_with CL:0000150 {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"} ! glandular epithelial cell

[Term]
id: AISM:0004236
name: unicellular ectodermal gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"one-celled gland usually larger than the cells surrounding it; discharges its products directly through the covering cuticula. [...] In many glands a minute cuticular ductule extends from the exterior into the body of each cell, allowing the secretion to pass out through an extremely thin layer of cuticula.\""}
def: "The ectodermal gland that is composed of one cell" [] {creation_date="2021-08-16", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004235 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ectodermal gland
relationship: has_part CL:0000000 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cell

[Term]
id: AISM:0004237
name: cuticular lobe {http://purl.org/dc/terms/modified="2021-12-08", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a rounded projection or protuberance\""}
def: "The cuticular evagination that is largely membranous." [] {creation_date="2021-06-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000128 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-06-14"} ! multicellular cuticular evagination
relationship: has_part AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-06-14"} ! conjunctiva

[Term]
id: AISM:0004238
name: multicellular ectodermal gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"many-celled glands may be a group of cells situated at the surface of the body, but most of them are invaginations of the body wall.\""}
def: "The ectodermal gland that is composed of multiple cells." [] {creation_date="2021-08-16", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004235 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! ectodermal gland

[Term]
id: AISM:0004239
name: occiput {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"dorsal part of the posterior surface of the head between the occipital and the postoccipital sutures\""}
def: "The region of cuticle on the posterodorsal region of the head capsule that is posterior to the occipital ridge and anterior to the postoccipital ridge." [] {creation_date="2021-08-16", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: anterior_to AISM:0004021 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postoccipital ridge
relationship: posterior_to AISM:0004048 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! occipital ridge

[Term]
id: AISM:0004240
name: epicranial suture {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Y-shaped ecdysial sutures dividing vertex and frons, composed of\ncoronal suture and paired frontal sutures.\""}
def: "The cuticular suture composed of both the coronal suture and paired frontal sutures." [] {creation_date="2021-08-16", http://purl.org/dc/terms/modified="2021-12-10", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004028 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular suture
relationship: has_part AISM:0004029 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frontal suture
relationship: has_part AISM:0004030 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coronal suture

[Term]
id: AISM:0004241
name: temple {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the part of the head above and behind the compound eyes\""}
def: "The region of cuticle that is behind the compound eye." [] {creation_date="2021-08-16", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: posterior_to AISM:0004052 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect compound eye

[Term]
id: AISM:0004242
name: insect wing region {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the principal areas of the wings differentiated in the wing-flexing insects (Neoptera), and often separated by distinct lines of folding, including the wing base, remigium, clavus, and jugum.\""}
def: "The region of cuticle of the insect wing that has wing veins, folds, and conjunctiva." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: has_part AISM:0004243 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein
relationship: has_part AISM:0004244 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold

[Term]
id: AISM:0004243
name: insect wing vein {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"sclerotized, tubular structure supporting the membrane of the wings\""}
def: "The region of cuticle of the insect wing that is less flexible than the wing conjunctiva." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: part_of AISM:0000033 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing

[Term]
id: AISM:0004244
name: insect wing fold {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"line along which wings fold at rest\""}
def: "The region of cuticle of the insect wing that is more flexible than the wing conjunctiva." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect region of cuticle
relationship: part_of AISM:0000033 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing

[Term]
id: AISM:0004245
name: anal field of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing field.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anal field (=vannus): posterior part of wings, usually enlarged in Polyneoptera.\""}
def: "The posterior region of the insect wing." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "vannus" EXACT []
is_a: AISM:0004242 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region
relationship: posterior_to AISM:0004311 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cubital field of the insect wing

[Term]
id: AISM:0004246
name: anal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anal veins: longitudinal veins of the anal field proximally articulated with 3rd axillary sclerite; usually unbranched and arranged like a fan.\""}
def: "The insect wing vein of the anal field that is posterior to the anal fold or the postcubitus and anterior to the jugal fold or the jugal veins." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004243 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein
relationship: RO:0001018 AISM:0004245 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! obsolete contained in anal field of the insect wing

[Term]
id: AISM:0004247
name: costal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Costa: main longitudinal vein along anterior wing margin, articulated with humeral plate.\""}
def: "The insect wing vein of the costal field that is anterior to the subcosta." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004243 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein
relationship: anterior_to AISM:0004257 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! subcostal vein of the insect wing
relationship: RO:0001018 AISM:0004248 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! obsolete contained in costal field of the insect wing

[Term]
id: AISM:0004248
name: costal field of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing field.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Costal field (=remigium): anterior part of wing; usually largest region.\""}
def: "The anterior region of the insect wing." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "remigium" EXACT []
is_a: AISM:0004242 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region
is_a: BSPO:0000078 ! distal region

[Term]
id: AISM:0004249
name: cubital vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Cubitus: 5th main longitudinal vein.\""}
def: "The insect wing vein that is posterior to the media and anterior to the postcubitus." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004243 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein
relationship: anterior_to AISM:0004255 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postcubital vein of the insect wing
relationship: posterior_to AISM:0004252 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! medial vein of the insect wing

[Term]
id: AISM:0004250
name: jugal field of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing field.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Jugal field: small wing region posteriorly adjacent with anal field.\""}
def: "The insect wing region that is posterior to the jugal fold." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004242 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region
relationship: posterior_to AISM:0004253 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! jugal fold of the insect wing

[Term]
id: AISM:0004251
name: jugal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Jugal veins: veins of the jugal field.\""}
def: "The insect wing vein in the jugal field, posterior to the jugal fold or to the anal veins." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004243 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein
relationship: RO:0001018 AISM:0004250 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! obsolete contained in jugal field of the insect wing

[Term]
id: AISM:0004252
name: medial vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Media: 4th main longitudinal vein.\""}
def: "The insect wing vein that is posterior to some radius and anterior to some cubitus." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004243 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein
relationship: anterior_to AISM:0004249 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cubital vein of the insect wing
relationship: posterior_to AISM:0004256 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! radial vein of the insect wing

[Term]
id: AISM:0004253
name: jugal fold of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing fold.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect wing fold that separates the anal field and the jugal field." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "plica jugalis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Plica jugalis: separates the anal and jugal fields.\""}
is_a: AISM:0004244 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold

[Term]
id: AISM:0004254
name: anal fold of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing fold.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect wing fold that is posterior to the postcubitus and separates the costal field and the anal field." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "claval furrow" EXACT [] {AISM:0000171="Chapman RF (2012) The Insects: Structure and Function. Fifth Edition. Cambridge University Press. 959 pp. \n\nhttps://doi.org/10.1017/CBO9781139035460\n\n\"longitudinal flexion line which runs close to the CuP. This furrow allows the posterior part of the wing to flap up and down with respect to the rest of the wing.\""}
synonym: "plica vannalis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Plica vannalis: separates the costal and anal fields.\""}
is_a: AISM:0004244 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold
relationship: posterior_to AISM:0004255 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postcubital vein of the insect wing

[Term]
id: AISM:0004255
name: postcubital vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Postcubitus: posteriormost longitudinal vein of the remigium.\""}
def: "The insect wing vein that is posterior to the cubitus and anterior to the anal fold or the anal vein." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004243 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein
relationship: posterior_to AISM:0004249 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cubital vein of the insect wing

[Term]
id: AISM:0004256
name: radial vein of the insect wing {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Radius: 3rd main longitudinal vein.\"", IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect wing vein that is posterior to the subcosta and anterior to the media." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004243 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein
relationship: anterior_to AISM:0004252 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! medial vein of the insect wing
relationship: posterior_to AISM:0004257 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! subcostal vein of the insect wing

[Term]
id: AISM:0004257
name: subcostal vein of the insect wing {IAO:0000232="Modified 2023-01-09: specifying insect wing vein.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Subcosta: 2nd main longitudinal vein, following costal vein.\""}
def: "The insect wing vein that is posterior to the costa and anterior to the radius." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004243 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing vein
relationship: anterior_to AISM:0004256 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! radial vein of the insect wing
relationship: posterior_to AISM:0004247 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! costal vein of the insect wing

[Term]
id: AISM:0004258
name: axillary region of the insect wing {IAO:0000232="Modified 2023-01-21: specifying insect wing region.\njgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"The region of the wing base containing the axillary sclerites\""}
def: "The proximal region of the insect wing." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004242 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing region
is_a: BSPO:0000078 ! distal region

[Term]
id: AISM:0004259
name: basal fold of the insect wing {comment="Modified 2023-01-21: specifying insect wing fold.\njgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect wing fold that is distal to the axillary region." [] {creation_date="2021-09-07", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "plica basalis" EXACT [] {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Plica basalis (bf).The basal fold of the wing, or line of flection between the base of the mediocubital fold and the axillary region, forming a prominent convex fold in the flexed wing extending between the median plates from the articulation of radius with the second axillary to the articulation of the vannal veins with the third axillary.\""}
is_a: AISM:0004244 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect wing fold
relationship: distal_to AISM:0004258 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! axillary region of the insect wing

[Term]
id: AISM:0004260
name: pretarsal claw {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ungues: pretarsal claws; unpaired in Collembola and Protura, usually paired in Diplura and Insecta.\""}
def: "The sclerite that is part of the pretarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"}
synonym: "ungues" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Ungues: pretarsal claws; unpaired in Collembola and Protura, usually paired in Diplura and Insecta.\""}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: part_of AISM:0000047 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus

[Term]
id: AISM:0004261
name: empodium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Empodium: a median process between the claws and pulvilli (if present). It arises from the distal end of the unguitractor plate, is spine-shaped or lobe-like and is sometimes similar in form to the pulvilli (“empodial pulvillus”).\" p. 43.", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"a spine- or lobelike process of the unguitractor\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticular protrusion that is part of the pretarsus, ventral to the tarsal claws and medial to the pulvilli (if present)." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19", IAO:0000232="Modified 2023-01-11: added medial to pulvilli.\njgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular protrusion
relationship: AISM:0000012 AISM:0004308 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! medial_to pulvillus
relationship: part_of AISM:0000047 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus
relationship: ventral_to AISM:0004260 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsal claw
property_value: IAO:0000589 "cuticle of empodium" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004262
name: frontoclypeal sulcus
def: "The sulcus that coincides with the frontoclypeal ridge and separated the frons from the clypeus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"}
synonym: "epistomal sulcus" EXACT [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "epistomal suture" EXACT [] {AISM:0000171="Lawrence J, Ślipiński A (2013) Adult morphology. In: Australian beetles volume 1: morphology, classification and keys. CSIRO Publishing, 30–63. \n\nhttps://www.publish.csiro.au/book/6466/\n\n[adjusted] the 'suture' separating the clypeus from the frons, representing the internal invagination of the epistomal ridge."}
synonym: "frontoclypeal suture" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the suture between the frons and the clypeus\""}
is_a: AISM:0000162 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular sulcus
relationship: adjacent_to AISM:0004019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! clypeus
relationship: adjacent_to AISM:0004020 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! frons
relationship: RO:0002008 AISM:0004034 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! coincident with frontoclypeal ridge

[Term]
id: AISM:0004263
name: cibarium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Anterior part of preoral space between epipharynx and hypopharynx.\"", creation_date="2021-12-15"}
def: "The conjunctiva that is part of the head capsule and is continuous with the epipharynx and the hypopharynx." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"}
is_a: AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! conjunctiva
relationship: continuous_with AISM:0000093 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! hypopharynx
relationship: continuous_with AISM:0000105 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! epipharynx
relationship: part_of AISM:0000019 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-12-15"} ! head capsule

[Term]
id: AISM:0004264
name: epistoma {creation_date="2022-02-21", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the oral margin or sclerite directly behind the labrum\""}
def: "The region of cuticle that is posterior to the cuticle of the labrum." [] {creation_date="2022-02-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! insect region of cuticle
relationship: posterior_to AISM:0000042 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! labrum

[Term]
id: AISM:0004265
name: subgenal sulcus {creation_date="2022-02-21", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the lateral submarginal groove of the cranium just above the bases of the gnathal appendages, extending between the anterior tentorial pit and the posterior tentorial pit\""}
def: "The cuticular sulcus that is adjacent to the subgena and coincides with the subgenal ridge." [] {creation_date="2022-02-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "subgenal suture" EXACT []
is_a: AISM:0000162 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! cuticular sulcus
relationship: adjacent_to AISM:0004027 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! subgena
relationship: RO:0002008 AISM:0004032 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-02-21"} ! coincident with subgenal ridge

[Term]
id: AISM:0004266
name: antennomere {creation_date="2022-06-20", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticle of a mere that is part of the cuticle of the antenna." [] {creation_date="2022-06-20", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000073 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! mere
relationship: part_of AISM:0000032 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! antenna
property_value: curator_notes "Given the high number of antennomeres occurring in some taxa, Arabic numerals are used instead of Roman numerals for practicality reasons." xsd:string {http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364", creation_date="2023-05-05"}
property_value: IAO:0000589 "cuticle of antennomere" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004267
name: postoccipital sulcus {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n[as postoccipital suture] \"posterior submarginal groove having the posterior tentorial pits in its lower end, separatig the postocciput from the rest of the cranium\"", creation_date="2022-06-17"}
def: "The cuticular sulcus that coincides with the postoccipital ridge and is posterior to the occiput and anterior to the postocciput." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"}
synonym: "postoccipital suture" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"posterior submarginal groove having the posterior tentorial pits in its lower end, separatig the postocciput from the rest of the cranium\""}
is_a: AISM:0000162 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! cuticular sulcus
relationship: anterior_to AISM:0004045 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! postocciput
relationship: posterior_to AISM:0004239 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! occiput
relationship: RO:0002008 AISM:0004021 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! coincident with postoccipital ridge

[Term]
id: AISM:0004268
name: gular sulcus {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n[as gular suture] \"the line or division between the gula and the genae\""}
def: "The cuticular sulcus that coincides with the gular ridge, separating the gula fron the gena" [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"}
synonym: "gular suture" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the line or division between the gula and the genae\""}
is_a: AISM:0000162 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! cuticular sulcus
relationship: adjacent_to AISM:0004026 {http://purl.org/dc/elements/1.1/contributor="2022-06-17", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! gena
relationship: adjacent_to AISM:0004035 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! gula
relationship: RO:0002008 AISM:0004036 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-17"} ! coincident with gular ridge

[Term]
id: AISM:0004269
name: mandibular incisor lobe {creation_date="2022-06-20", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"toothed distal lobe of mandible\""}
def: "The region of the cuticle that is distal and medial on the cuticle of the insect mandible." [] {creation_date="2022-06-20", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! insect region of cuticle

[Term]
id: AISM:0004270
name: mandibular molar lobe {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"the ridged or roughened grinding surface of the mandible\"", creation_date="2022-06-20"}
def: "The region of the cuticle that is proximal and medial on the cuticle of the insect mandible." [] {creation_date="2022-06-20", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "mola" EXACT [] {AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\nmola = molar lobe = \"the ridged or roughened grinding surface of the mandible\""}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! insect region of cuticle
is_a: BSPO:0000078 ! distal region

[Term]
id: AISM:0004271
name: prostheca {creation_date="2022-06-20", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"mandibular region set with hair\""}
def: "The cuticular lobe of the cuticle of the insect mandible between the mandibular molar lobe and the mandibular incisor lobe." [] {creation_date="2022-06-20", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "lacinia mobilis" EXACT [] {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"An articulated mesal appendage, the lacinia mobilis or prostheca, occurs in several groups. It can be sclerotized or largely membranous and is often equipped with microtrichia.\""}
is_a: AISM:0004237 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! cuticular lobe
relationship: anterior_to AISM:0004270 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! mandibular molar lobe
relationship: part_of AISM:0000043 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! insect mandible
relationship: posterior_to AISM:0004269 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-20"} ! mandibular incisor lobe

[Term]
id: AISM:0004272
name: basistipes {creation_date="2022-06-23", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Basistipes: basolateral part of stipes.\""}
def: "The region of cuticle on the lateral region of the cuticle of stipes, adjacent to the distal margin of the cuticle of the cardo, to the proximal margin of the cuticle of the palpifer, and adjacent to the proximal margin of the mediostipes." [] {creation_date="2022-06-23", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-23"} ! insect region of cuticle
is_a: BSPO:0000078 ! distal region

[Term]
id: AISM:0004273
name: mediostipes {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Mediostipes: mesal part of stipes.\""}
def: "The region of cuticle on the medial region of the cuticle of stipes, adjacent to the distal margin of the cuticle of the basistipes, and to the proximal margin of the cuticle of the galea and the lacinia." [] {creation_date="2022-06-23", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-23"} ! insect region of cuticle
is_a: BSPO:0000078 ! distal region

[Term]
id: AISM:0004274
name: maxillary gland {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Glands present in some insects opening mesally at the bases of the maxillae\""}
def: "The ectodermal gland continuous with the proximal region of the cuticle of the cardo." [] {creation_date="2022-06-23", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004235 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-23"} ! ectodermal gland

[Term]
id: AISM:0004275
name: hypopharyngeal sclerite
def: "The sclerite that is continuous with the hypopharynx." [] {creation_date="2022-06-27", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! insect sclerite
relationship: continuous_with AISM:0000093 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! hypopharynx

[Term]
id: AISM:0004276
name: thoracic foramen {creation_date="2022-06-27"}
def: "The arthropod foramen that is part of the cuticle of the insect thorax." [] {creation_date="2022-06-27", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0000197 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! arthropod foramen
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! insect thorax

[Term]
id: AISM:0004277
name: anterior prothoracic foramen {creation_date="2022-06-27"}
def: "The thoracic foramen that is at the anterior margin of the cuticle of the prothorax." [] {creation_date="2022-06-27", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004276 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen

[Term]
id: AISM:0004278
name: posterior prothoracic foramen {creation_date="2022-06-27"}
def: "The thoracic foramen that is at the posterior margin of the cuticle of the prothorax." [] {creation_date="2022-06-27", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004276 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen

[Term]
id: AISM:0004279
name: anterior mesothoracic foramen {creation_date="2022-06-27"}
def: "The thoracic foramen that is at the anterior margin of the cuticle of the mesothorax." [] {creation_date="2022-06-27", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004276 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen

[Term]
id: AISM:0004280
name: posterior mesothoracic foramen {creation_date="2022-06-27"}
def: "The thoracic foramen that is at the posterior margin of the cuticle of the mesothorax." [] {creation_date="2022-06-27", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004276 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen

[Term]
id: AISM:0004281
name: posterior metathoracic foramen {creation_date="2022-06-27"}
def: "The thoracic foramen that is at the posterior margin of the cuticle of the metathorax." [] {creation_date="2022-06-27", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004276 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen

[Term]
id: AISM:0004282
name: anterior metathoracic foramen {creation_date="2022-06-27"}
def: "The thoracic foramen that is at the anterior margin of the cuticle of the metathorax." [] {creation_date="2022-06-27", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004276 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2022-06-27"} ! thoracic foramen

[Term]
id: AISM:0004283
name: insect body segment {creation_date="2023-01-09", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"segment, subdivision of the body between areas of flexibility associated with muscle attachments\"", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect region of integument that is continuous with conjunctiva and attached to somatic muscle." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/fbcvq.html?query=FBbt\:00000003 "segment" {def="One of the repeated divisions of the whole organism."}
xref: http://purl.obolibrary.org/obo/HAO_0000929 "segment" {def="An anatomical structure that is metameric and is connected to other metameric subdivisions by muscles and is delimited by its sclerites."}
is_a: UBERON:6007284 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect region of integument
relationship: attaches_to UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! somatic muscle
relationship: continuous_with AISM:0000004 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! conjunctiva

[Term]
id: AISM:0004284
name: insect appendage segment {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Nichols, S. W. (1989) Torre-Bueno glossary of entomology. New York Entomological Society. 840 pp.\n\nhttps://ipmhouse.tamu.edu/files/2021/03/The-Torre-Bueno-Glossary-of-Entomology.pdf\n\n\"segment, subdivision of an appendage between areas of flexibility associated with muscle attachments\""}
def: "The insect region of integument that has a ring sclerirte, continuous with ring conjunctiva, and attached to somatic muscle." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: UBERON:6007284 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect region of integument
relationship: attaches_to UBERON:0014895 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! somatic muscle
relationship: continuous_with AISM:0000102 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! ring conjunctiva
relationship: has_part AISM:0000062 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! ring sclerite

[Term]
id: AISM:0004285
name: insect cephalic segment {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect body segment that is part of the insect head." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: https://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000006 "head segment" {def="Any segment (FBbt:00000003) that is part of some head (FBbt:00000004)."}
is_a: AISM:0004283 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect body segment
is_a: PR:000050567 ! protein-containing material entity
relationship: has_part AISM:0000107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect head

[Term]
id: AISM:0004286
name: insect thoracic segment {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect body segment that is part of the insect thorax." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000016 "thoracic segment" {def="Any segment (FBbt:00000003) that is part of some thorax (FBbt:00000015)."}
is_a: AISM:0004283 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect body segment
relationship: has_part AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thorax

[Term]
id: AISM:0004287
name: insect abdominal segment {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect body segment that is part of the insect abdomen." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000021 "abdominal segment" {def="Metameric subdivision of the abdomen."}
is_a: AISM:0004283 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect body segment
relationship: has_part AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdomen

[Term]
id: AISM:0004288
name: insect abdominal segment I {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect body segment that is part of the insect abdomen and is posterior to the insect metathoracic segment." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000022 "abdominal segment 1" {def="Most anterior segment of the abdomen."}
is_a: AISM:0004287 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment
relationship: has_part AISM:0000021 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite I
relationship: has_part AISM:0004100 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite I
relationship: posterior_to AISM:0004300 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect metathoracic segment

[Term]
id: AISM:0004289
name: insect abdominal segment II {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect abdominal segment that is posterior to the insect abdominal segment I and composed of abdominal tergite II and abdominal sternite II." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000023 "abdominal segment 2" {def="Second most anterior segment of the abdomen."}
is_a: AISM:0004287 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment
relationship: has_part AISM:0004085 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite II
relationship: has_part AISM:0004104 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite II
relationship: posterior_to AISM:0004288 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment I

[Term]
id: AISM:0004290
name: insect abdominal segment III {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect abdominal segment that is posterior to the insect abdominal segment II and composed of abdominal tergite III and abdominal sternite III." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000024 "abdominal segment 3" {def="Third most anterior segment of the abdomen."}
is_a: AISM:0004287 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment
relationship: has_part AISM:0004087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite III
relationship: has_part AISM:0004105 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite III
relationship: posterior_to AISM:0004289 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment II

[Term]
id: AISM:0004291
name: insect abdominal segment IV {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect abdominal segment that is posterior to the insect abdominal segment III and composed of abdominal tergite IV and abdominal sternite IV." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000025 "abdominal segment 4" {def="Fourth most anterior segment of the abdomen."}
is_a: AISM:0004287 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment
relationship: has_part AISM:0004090 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite IV
relationship: has_part AISM:0004106 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite IV
relationship: posterior_to AISM:0004290 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment III

[Term]
id: AISM:0004292
name: insect abdominal segment V {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect abdominal segment that is posterior to the insect abdominal segment IV and composed of abdominal tergite V and abdominal sternite V." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000026 "abdominal segment 5" {def="Fifth most anterior segment of the abdomen."}
is_a: AISM:0004287 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment
relationship: has_part AISM:0004091 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite V
relationship: has_part AISM:0004107 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite V
relationship: posterior_to AISM:0004291 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment IV

[Term]
id: AISM:0004293
name: insect abdominal segment VI {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect abdominal segment that is posterior to the insect abdominal segment V and composed of abdominal tergite VI and abdominal sternite VI." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000027 "abdominal segment 6" {def="Sixth most anterior segment of the abdomen."}
is_a: AISM:0004287 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment
relationship: has_part AISM:0004093 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite VI
relationship: has_part AISM:0004108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite VI
relationship: posterior_to AISM:0004292 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment V

[Term]
id: AISM:0004294
name: insect abdominal segment VII {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect abdominal segment that is posterior to the insect abdominal segment VI and composed of abdominal tergite VII and abdominal sternite VII." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000028 "abdominal segment 7" {def="Seventh most anterior segment of the abdomen."}
is_a: AISM:0004287 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment
relationship: has_part AISM:0004095 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite VII
relationship: has_part AISM:0004109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite VII
relationship: posterior_to AISM:0004293 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment VI

[Term]
id: AISM:0004295
name: insect abdominal segment VIII {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect abdominal segment that is posterior to the insect abdominal segment VII and composed of abdominal tergite VIII and abdominal sternite VIII." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000029 "abdominal segment 8" {def="Eigth most anterior segment of the abdomen."}
is_a: AISM:0004287 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment
relationship: has_part AISM:0004097 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite VIII
relationship: has_part AISM:0004110 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite VIII
relationship: posterior_to AISM:0004294 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment VII

[Term]
id: AISM:0004296
name: insect abdominal segment IX {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect abdominal segment that is posterior to the insect abdominal segment VIII and composed of abdominal tergite IX and abdominal sternite IX." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000030 "abdominal segment 9" {def="Ninth most anterior segment of the abdomen."}
is_a: AISM:0004287 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment
relationship: has_part AISM:0004117 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal tergite IX
relationship: has_part AISM:0004119 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! abdominal sternite IX
relationship: posterior_to AISM:0004295 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment VIII

[Term]
id: AISM:0004297
name: insect abdominal segment X {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect abdominal segment that is posterior to the insect abdominal segment IX and composed of abdominal tergite X and abdominal sternite X." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
xref: http://flybase.org/cgi-bin/cvreport.pl?cvterm=FBbt\:00000031 "abdominal segment 10" {def="Tenth most anterior segment of the abdomen."}
is_a: AISM:0004287 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment
relationship: posterior_to AISM:0004296 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect abdominal segment IX

[Term]
id: AISM:0004298
name: insect prothoracic segment {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect body segment that corresponds to the prothorax and is posterior to the insect cephalic segment." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004286 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thoracic segment
relationship: posterior_to AISM:0004285 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect cephalic segment

[Term]
id: AISM:0004299
name: insect mesothoracic segment {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect body segment that corresponds to the mesothorax and is posterior to the insect prothoracic segment." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004286 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thoracic segment
relationship: posterior_to AISM:0004298 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect prothoracic segment

[Term]
id: AISM:0004300
name: insect metathoracic segment {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The insect body segment that corresponds to the metathorax and is posterior to the insect mesothoracic segment." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004286 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect thoracic segment
relationship: posterior_to AISM:0004299 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect mesothoracic segment

[Term]
id: AISM:0004301
name: gonocoxite {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\"", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The bilaterally paired insect sclerite of the postabdomen, attached to either the abdominal tergite VIII or IX." [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
synonym: "coxopodite" EXACT [] {creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Coxopodite (=valvifer, gonocoxa, gonocoxite): short basal piece of ovipositor elements of female genital segments VIII and IX.\""}
is_a: AISM:0000003 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! insect sclerite
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0004056 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! postabdomen
property_value: IAO:0000589 "cuticle of gonocoxite" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004302
name: insect mouth {AISM:0000171="Snodgrass RE (1993) Principles of Insect Morphology. Cornell University Press, 768 pp.\n\nhttps://www.jstor.org/stable/10.7591/j.ctv1nhm1j\n\n\"Mouth. The external opening of the stomodaeum, situated in the ventral wall of the head between the labrum and the hypopharynx.\"", creation_date="2023-01-09", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
def: "The mouth that is surrounded by insect mandibles, labium, and labrum and is anterior to the hypopharynx." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883 2023-03-30", creation_date="2024-01-25"}
synonym: "preoral cavity" EXACT [] {creation_date="2023-01-09", AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"The preoral cavity is the space enclosed between the labrum and labium and the paired mandibles and maxillae\"", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: UBERON:0000165 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! mouth
relationship: anterior_to AISM:0000093 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! hypopharynx
relationship: surrounded_by AISM:0000042 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! labrum
relationship: surrounded_by AISM:0000043 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! insect mandible
relationship: surrounded_by AISM:0000087 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-09"} ! labium

[Term]
id: AISM:0004303
name: insect gland opening
def: "The orifice that is continuous with an ectodermal gland." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883 2023-03-30", creation_date="2024-01-25"}
is_a: UBERON:0000161 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! orifice
relationship: continuous_with AISM:0004235 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! ectodermal gland

[Term]
id: AISM:0004304
name: cuticular sensilla {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Sensilla are the basal functional and structural units of cuticular mechanoreceptors and chemoreceptors. They include the cuticular component (e.g., the cuticle of a seta), the sensory neuron (or neurons), the associated sheath cells with the cavities they enclose and the structures they produce\" p. 5.", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"}
def: "The region of cuticle that is attached to arthropod sensillum." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-10-11"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! insect region of cuticle
is_a: UBERON:0000061 ! anatomical structure
relationship: attaches_to UBERON:0002536 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! arthropod sensillum

[Term]
id: AISM:0004305
name: sensilla ampullacea {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Modified type of cuticular sensilla sunk below the external cuticular surface\"", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"}
def: "The cuticular sensilla that is dilated." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883 2023-03-30", creation_date="2024-01-25"}
xref: http://purl.obolibrary.org/obo/HAO_0001098 "basiconic capitate peg sensillum" {def="Mushroom-shaped sensory structure on the flagellum, particularly the\nclava; sometimes called the sensilla ampullacea."}
is_a: AISM:0004304 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular sensilla
relationship: has_characteristic PATO:0001571 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! dilated

[Term]
id: AISM:0004306
name: stridulatory file {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"}
def: "The region of the cuticle that bears an anatomical collection composed of cuticular carinae." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"}
is_a: AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! insect region of cuticle
relationship: has_member AISM:0000501 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular carina
relationship: has_part UBERON:0034925 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! anatomical collection

[Term]
id: AISM:0004307
name: pretarsal seta {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"}
def: "The cuticular seta that is adjacent to the cuticle of the pretarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"}
is_a: AISM:0000039 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! cuticular seta
relationship: adjacent_to AISM:0000047 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"} ! pretarsus

[Term]
id: AISM:0004308
name: pulvillus {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Pulvilli: smooth or hairy paired lateral membranous lobes below the claws\". p. 44.", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The cuticular protrusion that is part of the pretarsus, ventral to the tarsal claws." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2021-11-19"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! cuticular protrusion
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! bilaterally paired
relationship: part_of AISM:0000047 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsus
relationship: ventral_to AISM:0004260 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"} ! pretarsal claw
property_value: IAO:0000589 "cuticle of pulvillus" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004309
name: arolium {AISM:0000171="Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Arolium: the median hollow lobe of the pretarsus. It can be completely membranous or partly sclerotized.\" p. 42.\n\"unpaired, between the claws\" p. 40.", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11", IAO:0000232="Modified 2023-04-13: removed ‘cuticle of’ from label.\nstarasov https://orcid.org/0000-0001-5237-2330"}
def: "The medial cuticular protrusion of the pretarsus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-11"}
property_value: IAO:0000589 "cuticle of arolium" xsd:string {creation_date="2023-04-13"}

[Term]
id: AISM:0004310
name: radial field of the insect wing
def: "The region of the insect wing that is posterior to the costal field of the insect wing." [] {creation_date="2023-01-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004242 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! insect wing region
relationship: posterior_to AISM:0004248 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! costal field of the insect wing

[Term]
id: AISM:0004311
name: cubital field of the insect wing
def: "The region of the insect wing that is posterior to the medial field of the insect wing." [] {creation_date="2023-01-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004242 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! insect wing region
relationship: posterior_to AISM:0004312 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! medial field of the insect wing

[Term]
id: AISM:0004312
name: medial field of the insect wing
def: "The region of the insect wing that is posterior to the radial field of the insect wing." [] {creation_date="2023-01-21", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
is_a: AISM:0004242 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! insect wing region
relationship: posterior_to AISM:0004310 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-01-21"} ! radial field of the insect wing

[Term]
id: AISM:0004313
name: tracheal gill {AISM:0000171="http://insecta.bio.spbu.ru/z/antidictionary/tergalii&gills.htm\n\n\"Paraspiracular tracheal gill. Paired abdominal appendage, whose trachea arises either directly from the spiracular trachea of the same abdominal segment, or from the nearest point of tracheae branching\"", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"}
def: "The bilaterally paired cuticular protrusion that contains insect tracheae." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"}
is_a: AISM:0000008 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! cuticular protrusion
relationship: has_characteristic PATO:0040024 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! bilaterally paired
relationship: has_part AISM:0000091 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect trachea

[Term]
id: AISM:0004314
name: insect thoracic spiracle {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"}
def: "The insect spiracle that is part of the insect thorax." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"}
is_a: AISM:0000135 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect spiracle
relationship: part_of AISM:0000108 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect thorax

[Term]
id: AISM:0004315
name: insect abdominal insect spiracle {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"}
def: "The insect spiracle that is part of the insect abdomen." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"}
is_a: AISM:0000135 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect spiracle
relationship: part_of AISM:0000109 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2023-02-05"} ! insect abdomen

[Term]
id: AISM:0004316
name: insect external male genitalia {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"}
def: "The external male genitalia with insect cuticle and composed of phallobase, phallobasal-parameral conjunctiva, paramere (or parameres), paramero-aedeagal conjunctiva, aedeagus, and endophallus." [] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", http://purl.org/dc/elements/1.1/creator="2024-01-12"}
is_a: UBERON:0004053 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! external male genitalia
relationship: has_component AISM:0000174 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! insect region of cuticle
relationship: has_part AISM:0004062 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! aedeagus
relationship: has_part AISM:0004063 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! endophallus
relationship: has_part AISM:0004065 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! phallobase
relationship: has_part AISM:0004200 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! paramero-aedeagal conjunctiva
relationship: has_part AISM:0004201 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-01-12"} ! phallobasal-parameral conjunctiva

[Term]
id: AISM:0004317
name: deflexed {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"}
def: "A quality inhering in a bearer by virtue of the bearer's surface becoming bent or curving downward or backward." [Oxford Languages through Google.] {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"}
is_a: PATO:0001591 {http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883", creation_date="2024-02-14"} ! curvature

[Term]
id: BFO:0000001
name: entity
property_value: BFO:0000179 "entity" xsd:string
property_value: BFO:0000180 "Entity" xsd:string
property_value: editor_note "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81" xsd:string
property_value: editor_note "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000004", comment="per discussion with Barry Smith", seeAlso="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"}
property_value: IAO:0000112 "Julius Caesar" xsd:string
property_value: IAO:0000112 "the Second World War" xsd:string
property_value: IAO:0000112 "Verdi’s Requiem" xsd:string
property_value: IAO:0000112 "your body mass index" xsd:string
property_value: IAO:0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/001-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000002
name: continuant
def: "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." []
is_a: BFO:0000001 ! entity
disjoint_from: BFO:0000003 ! occurrent
relationship: part_of BFO:0000002 {all_only="true"} ! continuant
property_value: BFO:0000179 "continuant" xsd:string
property_value: BFO:0000180 "Continuant" xsd:string
property_value: editor_note "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240" xsd:string
property_value: editor_note "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000007"}
property_value: IAO:0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"}
property_value: IAO:0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"}
property_value: IAO:0000601 "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"}
property_value: IAO:0000601 "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"}
property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"}
property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"}
property_value: IAO:0000602 "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"}
property_value: IAO:0000602 "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000003
name: occurrent
def: "An entity that has temporal parts and that happens, unfolds or develops through time." []
is_a: BFO:0000001 ! entity
relationship: part_of BFO:0000003 {all_only="true"} ! occurrent
property_value: BFO:0000179 "occurrent" xsd:string
property_value: BFO:0000180 "Occurrent" xsd:string
property_value: editor_note "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region" xsd:string
property_value: editor_note "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players." xsd:string
property_value: editor_note "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000006", comment="per discussion with Barry Smith"}
property_value: editor_note "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000012"}
property_value: IAO:0000589 "processual entity (BFO)" xsd:string
property_value: IAO:0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/077-002"}
property_value: IAO:0000601 "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"}
property_value: IAO:0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"}
property_value: IAO:0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"}
property_value: IAO:0000602 "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000004
name: independent continuant
def: "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything." []
def: "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"}
comment: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
is_a: BFO:0000002 ! continuant
disjoint_from: BFO:0000020 ! characteristic
disjoint_from: BFO:0000031 ! generically dependent continuant
relationship: part_of BFO:0000004 {all_only="true"} ! independent continuant
property_value: BFO:0000179 "ic" xsd:string
property_value: BFO:0000180 "IndependentContinuant" xsd:string
property_value: IAO:0000112 "a chair" xsd:string
property_value: IAO:0000112 "a heart" xsd:string
property_value: IAO:0000112 "a leg" xsd:string
property_value: IAO:0000112 "a molecule" xsd:string
property_value: IAO:0000112 "a spatial region" xsd:string
property_value: IAO:0000112 "an atom" xsd:string
property_value: IAO:0000112 "an orchestra." xsd:string
property_value: IAO:0000112 "an organism" xsd:string
property_value: IAO:0000112 "the bottom right portion of a human torso" xsd:string
property_value: IAO:0000112 "the interior of your mouth" xsd:string
property_value: IAO:0000589 "anatomical entity (BFO)" xsd:string
property_value: IAO:0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"}
property_value: IAO:0000601 "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"}
property_value: IAO:0000602 "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"}
property_value: IAO:0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"}
property_value: IAO:0000602 "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000006
name: spatial region
is_a: BFO:0000141 ! immaterial entity
property_value: BFO:0000179 "s-region" xsd:string
property_value: BFO:0000180 "SpatialRegion" xsd:string
property_value: editor_note "BFO 2 Reference: Spatial regions do not participate in processes." xsd:string
property_value: editor_note "Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000002", comment="per discussion with Barry Smith"}
property_value: IAO:0000600 "A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/035-001"}
property_value: IAO:0000601 "All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/036-001"}
property_value: IAO:0000602 "(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/036-001"}
property_value: IAO:0000602 "(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/035-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000009
name: two-dimensional spatial region
is_a: BFO:0000006 ! spatial region
property_value: BFO:0000179 "2d-s-region" xsd:string
property_value: BFO:0000180 "TwoDimensionalSpatialRegion" xsd:string
property_value: IAO:0000112 "an infinitely thin plane in space." xsd:string
property_value: IAO:0000112 "the surface of a sphere-shaped part of space" xsd:string
property_value: IAO:0000600 "A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/039-001"}
property_value: IAO:0000602 "(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/039-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000015
name: process
def: "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." []
def: "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"}
comment: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
is_a: BFO:0000003 ! occurrent
relationship: part_of BFO:0000015 {all_only="true"} ! process
property_value: BFO:0000179 "process" xsd:string
property_value: BFO:0000180 "Process" xsd:string
property_value: editor_note "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)" xsd:string
property_value: IAO:0000112 "a process of cell-division, \\ a beating of the heart" xsd:string
property_value: IAO:0000112 "a process of meiosis" xsd:string
property_value: IAO:0000112 "a process of sleeping" xsd:string
property_value: IAO:0000112 "the course of a disease" xsd:string
property_value: IAO:0000112 "the flight of a bird" xsd:string
property_value: IAO:0000112 "the life of an organism" xsd:string
property_value: IAO:0000112 "your process of aging." xsd:string
property_value: IAO:0000602 "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000016
name: disposition
is_a: BFO:0000017 ! realizable entity
disjoint_from: BFO:0000023 ! role
property_value: BFO:0000179 "disposition" xsd:string
property_value: BFO:0000180 "Disposition" xsd:string
property_value: editor_note "BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type." xsd:string
property_value: IAO:0000112 "an atom of element X has the disposition to decay to an atom of element Y" xsd:string
property_value: IAO:0000112 "certain people have a predisposition to colon cancer" xsd:string
property_value: IAO:0000112 "children are innately disposed to categorize objects in certain ways." xsd:string
property_value: IAO:0000112 "the cell wall is disposed to filter chemicals in endocytosis and exocytosis" xsd:string
property_value: IAO:0000600 "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/062-002"}
property_value: IAO:0000601 "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/063-002"}
property_value: IAO:0000602 "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/063-002"}
property_value: IAO:0000602 "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/062-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000017
name: realizable
name: realizable entity
def: "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances." []
is_a: BFO:0000020 ! characteristic
disjoint_from: BFO:0000019 ! quality
relationship: part_of BFO:0000017 {all_only="true"} ! realizable entity
property_value: BFO:0000179 "realizable" xsd:string
property_value: BFO:0000180 "RealizableEntity" xsd:string
property_value: IAO:0000112 "the disposition of this piece of metal to conduct electricity." xsd:string
property_value: IAO:0000112 "the disposition of your blood to coagulate" xsd:string
property_value: IAO:0000112 "the function of your reproductive organs" xsd:string
property_value: IAO:0000112 "the role of being a doctor" xsd:string
property_value: IAO:0000112 "the role of this boundary to delineate where Utah and Colorado meet" xsd:string
property_value: IAO:0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"}
property_value: IAO:0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"}
property_value: IAO:0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"}
property_value: IAO:0000602 "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000019
name: quality
namespace: bfo
is_a: BFO:0000020 ! characteristic
relationship: part_of BFO:0000019 {all_only="true"} ! quality
property_value: BFO:0000179 "quality" xsd:string
property_value: BFO:0000180 "Quality" xsd:string
property_value: IAO:0000112 "the ambient temperature of this portion of air" xsd:string
property_value: IAO:0000112 "the color of a tomato" xsd:string
property_value: IAO:0000112 "the length of the circumference of your waist" xsd:string
property_value: IAO:0000112 "the mass of this piece of gold." xsd:string
property_value: IAO:0000112 "the shape of your nose" xsd:string
property_value: IAO:0000112 "the shape of your nostril" xsd:string
property_value: IAO:0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"}
property_value: IAO:0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"}
property_value: IAO:0000602 "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"}
property_value: IAO:0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000020
name: characteristic
name: specifically dependent continuant
def: "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same." []
def: "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"}
comment: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
is_a: BFO:0000002 ! continuant
disjoint_from: BFO:0000031 ! generically dependent continuant
relationship: has_part BFO:0000020 {all_only="true"} ! characteristic
relationship: part_of BFO:0000020 {all_only="true"} ! characteristic
property_value: BFO:0000179 "sdc" xsd:string
property_value: BFO:0000180 "SpecificallyDependentContinuant" xsd:string
property_value: editor_note "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc." xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000005", comment="per discussion with Barry Smith"}
property_value: IAO:0000112 "of one-sided specifically dependent continuants: the mass of this tomato" xsd:string
property_value: IAO:0000112 "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates." xsd:string
property_value: IAO:0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key" xsd:string
property_value: IAO:0000112 "the disposition of this fish to decay" xsd:string
property_value: IAO:0000112 "the function of this heart: to pump blood" xsd:string
property_value: IAO:0000112 "the mutual dependence of proton donors and acceptors in chemical reactions [79" xsd:string
property_value: IAO:0000112 "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction" xsd:string
property_value: IAO:0000112 "the pink color of a medium rare piece of grilled filet mignon at its center" xsd:string
property_value: IAO:0000112 "the role of being a doctor" xsd:string
property_value: IAO:0000112 "the shape of this hole." xsd:string
property_value: IAO:0000112 "the smell of this portion of mozzarella" xsd:string
property_value: IAO:0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
property_value: seeAlso "https://github.com/OBOFoundry/COB/issues/65" xsd:string
property_value: seeAlso "https://github.com/oborel/obo-relations/pull/284" xsd:string

[Term]
id: BFO:0000023
name: role
def: "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts." []
is_a: BFO:0000017 ! realizable entity
property_value: BFO:0000179 "role" xsd:string
property_value: BFO:0000180 "Role" xsd:string
property_value: editor_note "BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals –  professor, sergeant, nurse – only during certain phases in their lives." xsd:string
property_value: IAO:0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married." xsd:string
property_value: IAO:0000112 "the priest role" xsd:string
property_value: IAO:0000112 "the role of a boundary to demarcate two neighboring administrative territories" xsd:string
property_value: IAO:0000112 "the role of a building in serving as a military target" xsd:string
property_value: IAO:0000112 "the role of a stone in marking a property boundary" xsd:string
property_value: IAO:0000112 "the role of subject in a clinical trial" xsd:string
property_value: IAO:0000112 "the student role" xsd:string
property_value: IAO:0000600 "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/061-001"}
property_value: IAO:0000602 "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/061-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000030
name: object
namespace: bfo
is_a: BFO:0000040 ! material entity

[Term]
id: BFO:0000031
name: generically dependent continuant
def: "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])" [] {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"}
comment: A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.
is_a: BFO:0000002 ! continuant
relationship: part_of BFO:0000031 {all_only="true"} ! generically dependent continuant
property_value: BFO:0000179 "gdc" xsd:string
property_value: BFO:0000180 "GenericallyDependentContinuant" xsd:string
property_value: IAO:0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity." xsd:string
property_value: IAO:0000112 "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop" xsd:string
property_value: IAO:0000112 "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule." xsd:string
property_value: IAO:0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000034
name: function
is_a: BFO:0000016 ! disposition
property_value: BFO:0000179 "function" xsd:string
property_value: BFO:0000180 "Function" xsd:string
property_value: editor_note "BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc." xsd:string
property_value: IAO:0000112 "the function of a hammer to drive in nails" xsd:string
property_value: IAO:0000112 "the function of a heart pacemaker to regulate the beating of a heart through electricity" xsd:string
property_value: IAO:0000112 "the function of amylase in saliva to break down starch into sugar" xsd:string
property_value: IAO:0000600 "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/064-001"}
property_value: IAO:0000602 "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/064-001"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000040
name: material entity
namespace: bfo
def: "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." []
is_a: BFO:0000004 ! independent continuant
disjoint_from: BFO:0000141 ! immaterial entity
property_value: BFO:0000179 "material" xsd:string
property_value: BFO:0000180 "MaterialEntity" xsd:string
property_value: editor_note "BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60" xsd:string
property_value: editor_note "BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity." xsd:string
property_value: editor_note "BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here." xsd:string
property_value: IAO:0000112 "a flame" xsd:string
property_value: IAO:0000112 "a forest fire" xsd:string
property_value: IAO:0000112 "a human being" xsd:string
property_value: IAO:0000112 "a hurricane" xsd:string
property_value: IAO:0000112 "a photon" xsd:string
property_value: IAO:0000112 "a puff of smoke" xsd:string
property_value: IAO:0000112 "a sea wave" xsd:string
property_value: IAO:0000112 "a tornado" xsd:string
property_value: IAO:0000112 "an aggregate of human beings." xsd:string
property_value: IAO:0000112 "an energy wave" xsd:string
property_value: IAO:0000112 "an epidemic" xsd:string
property_value: IAO:0000112 "the undetached arm of a human being" xsd:string
property_value: IAO:0000600 "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"}
property_value: IAO:0000601 "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"}
property_value: IAO:0000601 "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])" xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"}
property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"}
property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"}
property_value: IAO:0000602 "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] " xsd:string {IAO:0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"}
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BFO:0000141
name: immaterial entity
is_a: BFO:0000004 ! independent continuant
property_value: BFO:0000179 "immaterial" xsd:string
property_value: BFO:0000180 "ImmaterialEntity" xsd:string
property_value: editor_note "BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10" xsd:string
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Term]
id: BSPO:0000000
name: left side
namespace: spatial
def: "The side of an organism that is left of the sagittal plane." [BSPO:cjm]
synonym: "left" EXACT []
is_a: BSPO:0000054 ! anatomical side
relationship: left_of BSPO:0000007 ! right side
relationship: starts_axis BSPO:0000017 ! left-right axis

[Term]
id: BSPO:0000001
name: upper side
namespace: spatial
comment: Consider merging with superior side.
synonym: "upper" EXACT []
is_a: BSPO:0000054 ! anatomical side
relationship: starts_axis BSPO:0000011 ! upper-lower axis

[Term]
id: BSPO:0000002
name: lower side
namespace: spatial
comment: Consider merging with inferior side.
synonym: "lower" EXACT []
is_a: BSPO:0000054 ! anatomical side
relationship: finishes_axis BSPO:0000011 ! upper-lower axis

[Term]
id: BSPO:0000005
name: anatomical surface
namespace: spatial
def: "A 2D surface of an anatomical continuant." [BSPO:cjm]
comment: to be merged into CARO
synonym: "surface" EXACT []
xref: FMA:24137
is_a: CARO:0000010 ! anatomical boundary

[Term]
id: BSPO:0000006
name: anatomical margin
namespace: spatial
def: "Fiat anatomical region extending a short distance from the boundary of an object inwards." [BSPO:cjm]
synonym: "edge" EXACT []
synonym: "margin" EXACT []
is_a: BSPO:0000070 ! anatomical region

[Term]
id: BSPO:0000007
name: right side
namespace: spatial
def: "The side of an organism that is right of the sagittal plane." [BSPO:cjm, BSPO:wd]
synonym: "right" EXACT []
is_a: BSPO:0000054 ! anatomical side
relationship: finishes_axis BSPO:0000017 ! left-right axis

[Term]
id: BSPO:0000010
name: anatomical axis
namespace: spatial
def: "A straight line through space, intersecting an anatomical entity." [BSPO:cjm]
comment: Axis directions are defined in terms of axes.
xref: http://upload.wikimedia.org/wikipedia/commons/3/34/Anatomical_Directions_and_Axes.JPG
is_a: CARO:0000008 ! anatomical line
relationship: passes_through CARO:0000000 ! anatomical entity

[Term]
id: BSPO:0000011
name: upper-lower axis
namespace: spatial
def: "An anatomical axis determined by gravity." [BSPO:cjm]
synonym: "superior-inferior axis" RELATED []
is_a: BSPO:0000010 ! anatomical axis

[Term]
id: BSPO:0000013
name: anterior-posterior axis
namespace: spatial
def: "An axis that extends through an organism from head end to opposite end of body or tail." [BSPO:cjm]
comment: In sponges, AP is used to indicate the direction of movement [in larval stage] (as it is in other metazoans that move, e.g., the basal bilaterians). [PM]
synonym: "A-P axis" EXACT []
synonym: "anteroposterior axis" EXACT []
synonym: "AP axis" EXACT []
synonym: "cephalocaudal axis" NARROW [http://en.wikipedia.org/wiki/Anatomical_terms_of_location]
synonym: "craniocaudal axis" NARROW vertebrate []
synonym: "longitudinal axis" RELATED []
synonym: "rostral/caudal" NARROW vertebrate []
synonym: "rostrocaudal axis" NARROW vertebrate []
is_a: BSPO:0000010 ! anatomical axis
intersection_of: BSPO:0000010 ! anatomical axis
intersection_of: orthogonal_to BSPO:0000018 ! transverse plane
relationship: approximately_perpendicular_to BSPO:0000016 ! dorsal-ventral axis
relationship: orthogonal_to BSPO:0000018 ! transverse plane

[Term]
id: BSPO:0000015
name: proximal-distal axis
namespace: spatial
def: "An axis that extends from the point of attachment of a structure (proximal) to the  point furthest away from the plane of attachment (distal)." [BSPO:curators, http://en.wikipedia.org/wiki/Anatomical_terms_of_location]
comment: In some communities, proximal and distal are used when specifying the position of parts of elements that are contained within the body, such as gill arches or vertebral spines. In these cases, use of the classes medial-lateral axis or medial-external axis are more appropriate.
synonym: "proximal/distal" EXACT []
synonym: "proximodistal" EXACT []
is_a: BSPO:0000010 ! anatomical axis

[Term]
id: BSPO:0000016
name: dorsal-ventral axis
namespace: spatial
def: "An axis that is approximately perpendicular to the anterior-posterior axis and that extends through the horizontal plane of the body." [BSPO:curators]
synonym: "anterior-posterior axis" NARROW human []
synonym: "D-V axis" EXACT []
synonym: "dorsoventral axis" EXACT []
synonym: "DV axis" EXACT []
is_a: BSPO:0000010 ! anatomical axis
intersection_of: BSPO:0000010 ! anatomical axis
intersection_of: orthogonal_to BSPO:0000019 ! horizontal plane
relationship: orthogonal_to BSPO:0000019 ! horizontal plane

[Term]
id: BSPO:0000017
name: left-right axis
namespace: spatial
def: "An axis that bisects an organism from left to right sides of body, through a sagittal plane." [BSPO:cjm]
synonym: "dextro-sinister axis" EXACT []
synonym: "L-R axis" EXACT []
synonym: "left to right axis" EXACT []
synonym: "LR axis" EXACT []
synonym: "R-L axis" EXACT []
synonym: "right to left axis" EXACT []
synonym: "right-left axis" EXACT []
synonym: "RL axis" EXACT []
is_a: BSPO:0000010 ! anatomical axis
intersection_of: BSPO:0000010 ! anatomical axis
intersection_of: orthogonal_to BSPO:0000417 ! sagittal plane
relationship: orthogonal_to BSPO:0000417 ! sagittal plane

[Term]
id: BSPO:0000018
name: transverse plane
namespace: spatial
def: "Anatomical plane that divides body into anterior and posterior parts." [BSPO:mah]
synonym: "axial plane" EXACT []
synonym: "axial section" EXACT []
synonym: "cross-section" RELATED []
synonym: "transverse section" EXACT []
xref: FMA:12247
is_a: BSPO:0000400 ! anatomical plane

[Term]
id: BSPO:0000019
name: horizontal plane
namespace: spatial
def: "Anatomical plane that divides bilateral body into dorsal and ventral parts." [BSPO:mah]
synonym: "coronal section" RELATED []
synonym: "frontal plane" EXACT []
synonym: "frontal section" RELATED []
synonym: "horizontal anatomical plane" EXACT [FMA:52810]
synonym: "horizontal section" EXACT []
xref: FMA:52810
is_a: BSPO:0000400 ! anatomical plane

[Term]
id: BSPO:0000026
name: antero-dorsal region
namespace: spatial
def: "Anatomical region that overlaps the anterior and dorsal regions of a body or body part." [BSPO:wd]
synonym: "anterodorsal region " EXACT []
is_a: BSPO:0000071 ! anterior region
is_a: BSPO:0000079 ! dorsal region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000055 ! anterior side
intersection_of: overlaps BSPO:0000063 ! dorsal side
created_by: Melissa  Haendel
creation_date: 2009-06-15T01:01:38Z

[Term]
id: BSPO:0000027
name: antero-ventral region
namespace: spatial
def: "Anatomical region that overlaps the anterior and ventral regions of a body or body part." [BSPO:wd]
synonym: "anteroventral region " EXACT []
is_a: BSPO:0000071 ! anterior region
is_a: BSPO:0000084 ! ventral region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000055 ! anterior side
intersection_of: overlaps BSPO:0000068 ! ventral side
created_by: Melissa  Haendel
creation_date: 2009-06-15T01:04:59Z

[Term]
id: BSPO:0000028
name: postero-lateral region
namespace: spatial
def: "Anatomical region that overlaps the posterior and lateral regions of the body or body part." [BSPO:wd]
synonym: "posterolateral region" EXACT []
is_a: BSPO:0000072 ! posterior region
is_a: BSPO:0000082 ! lateral region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000056 ! posterior side
intersection_of: overlaps BSPO:0000066 ! lateral side
created_by: Melissa  Haendel
creation_date: 2009-06-15T01:06:01Z

[Term]
id: BSPO:0000029
name: antero-lateral region
namespace: spatial
def: "Anatomical region that overlaps the anterior and lateral regions of a body or body part." [BSPO:wd]
synonym: "anterolateral region" EXACT []
is_a: BSPO:0000071 ! anterior region
is_a: BSPO:0000082 ! lateral region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000055 ! anterior side
intersection_of: overlaps BSPO:0000066 ! lateral side
created_by: Melissa  Haendel
creation_date: 2009-06-15T01:07:18Z

[Term]
id: BSPO:0000030
name: postero-dorsal region
namespace: spatial
def: "Anatomical region that overlaps the posterior and dorsal regions of the body or body part." [BSPO:wd]
synonym: "posterodorsal region" EXACT []
is_a: BSPO:0000072 ! posterior region
is_a: BSPO:0000079 ! dorsal region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000056 ! posterior side
intersection_of: overlaps BSPO:0000063 ! dorsal side
created_by: Melissa  Haendel
creation_date: 2009-06-15T01:08:13Z

[Term]
id: BSPO:0000031
name: upper region
namespace: spatial
is_a: BSPO:0000070 ! anatomical region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000001 ! upper side
relationship: overlaps BSPO:0000001 ! upper side

[Term]
id: BSPO:0000032
name: lower region
namespace: spatial
is_a: BSPO:0000070 ! anatomical region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000002 ! lower side
relationship: overlaps BSPO:0000002 ! lower side

[Term]
id: BSPO:0000035
name: postero-ventral region
namespace: spatial
def: "Anatomical region that overlaps the posterior and ventral regions of a body or body part." [BSPO:wd]
synonym: "posteroventral region" EXACT []
is_a: BSPO:0000072 ! posterior region
is_a: BSPO:0000084 ! ventral region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000056 ! posterior side
intersection_of: overlaps BSPO:0000068 ! ventral side
created_by: Melissa  Haendel
creation_date: 2009-06-15T01:08:38Z

[Term]
id: BSPO:0000042
name: antero-medial margin
namespace: spatial
def: "Anatomical margin that is located on the antero-medial region of the body or body part." [BSPO:wd]
synonym: "anteromedial margin" EXACT []
is_a: BSPO:0000050 ! antero-medial region
is_a: BSPO:0000671 ! anterior margin
is_a: BSPO:0000683 ! medial margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000055 ! anterior side
intersection_of: overlaps BSPO:0000067 ! medial side
created_by: Melissa  Haendel
creation_date: 2009-09-10T08:49:57Z

[Term]
id: BSPO:0000045
name: antero-lateral margin
namespace: spatial
def: "Anatomical margin that is located on the antero-lateral region of the body or body part." [BSPO:wd]
synonym: "anterolateral margin" EXACT []
is_a: BSPO:0000029 ! antero-lateral region
is_a: BSPO:0000671 ! anterior margin
is_a: BSPO:0000682 ! lateral margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000055 ! anterior side
intersection_of: overlaps BSPO:0000066 ! lateral side
created_by: Melissa  Haendel
creation_date: 2009-09-10T08:50:37Z

[Term]
id: BSPO:0000046
name: postero-medial margin
namespace: spatial
def: "Anatomical margin that is located on the postero-medial region of the body or body part." [BSPO:wd]
synonym: "posteromedial margin" EXACT []
is_a: BSPO:0000064 ! postero-medial region
is_a: BSPO:0000672 ! posterior margin
is_a: BSPO:0000683 ! medial margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000056 ! posterior side
intersection_of: overlaps BSPO:0000067 ! medial side
created_by: Melissa  Haendel
creation_date: 2009-09-10T08:51:07Z

[Term]
id: BSPO:0000047
name: postero-lateral margin
namespace: spatial
def: "Anatomical margin that is located on the postero-lateral region of the body or body part." [BSPO:wd]
synonym: "posterolateral margin" EXACT []
is_a: BSPO:0000028 ! postero-lateral region
is_a: BSPO:0000672 ! posterior margin
is_a: BSPO:0000682 ! lateral margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000056 ! posterior side
intersection_of: overlaps BSPO:0000066 ! lateral side
created_by: Melissa  Haendel
creation_date: 2009-09-10T08:51:42Z

[Term]
id: BSPO:0000048
name: dorso-medial margin
namespace: spatial
def: "Anatomical margin that is located on the dorso-medial region of the body or body part." [BSPO:wd]
synonym: "dorso-medial margin" EXACT []
is_a: BSPO:0000069 ! dorso-medial region
is_a: BSPO:0000679 ! dorsal margin
is_a: BSPO:0000683 ! medial margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000063 ! dorsal side
intersection_of: overlaps BSPO:0000067 ! medial side
created_by: Melissa  Haendel
creation_date: 2009-09-10T08:52:04Z

[Term]
id: BSPO:0000049
name: ventro-medial margin
namespace: spatial
def: "Anatomical margin that is located on the ventro-medial region of the body or body part." [BSPO:wd]
synonym: "ventromedial margin" EXACT []
is_a: BSPO:0000112 ! ventro-medial region
is_a: BSPO:0000683 ! medial margin
is_a: BSPO:0000684 ! ventral margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000067 ! medial side
intersection_of: overlaps BSPO:0000068 ! ventral side
created_by: Melissa  Haendel
creation_date: 2009-09-10T08:52:48Z

[Term]
id: BSPO:0000050
name: antero-medial region
namespace: spatial
def: "Anatomical region that overlaps the anterior and medial regions of the body or body part." [BSPO:wd]
synonym: "anteromedial region" EXACT []
is_a: BSPO:0000071 ! anterior region
is_a: BSPO:0000083 ! medial region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000055 ! anterior side
intersection_of: overlaps BSPO:0000067 ! medial side
created_by: Melissa  Haendel
creation_date: 2009-09-10T08:55:32Z

[Term]
id: BSPO:0000054
name: anatomical side
namespace: spatial
def: "An anatomical region bounded by a plane perpendicular to an axis through the middle." [BSPO:cjm]
xref: FBql:00005841
is_a: BSPO:0000070 ! anatomical region

[Term]
id: BSPO:0000055
name: anterior side
namespace: spatial
def: "An anatomical region that is the entire part of an anatomical structure anterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:RW]
synonym: "anterior" EXACT []
synonym: "rostral" EXACT []
xref: FBcv:0000053
xref: FBql:00005848
is_a: BSPO:0000054 ! anatomical side
relationship: anterior_to BSPO:0000056 ! posterior side
relationship: opposite_to BSPO:0000056 ! posterior side
relationship: starts_axis BSPO:0000013 ! anterior-posterior axis

[Term]
id: BSPO:0000056
name: posterior side
namespace: spatial
def: "An anatomical region that is the entire part of an anatomical structure posterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:RW, BSPO:wd]
synonym: "caudal" NARROW vertebrate []
synonym: "posterior" EXACT []
xref: FBcv:0000065
xref: FBql:00005849
is_a: BSPO:0000054 ! anatomical side
relationship: finishes_axis BSPO:0000013 ! anterior-posterior axis
relationship: posterior_to BSPO:0000055 ! anterior side

[Term]
id: BSPO:0000061
name: proximal side
namespace: spatial
synonym: "proximal" EXACT []
xref: FBcv:0000066
xref: FBql:00005852
is_a: BSPO:0000054 ! anatomical side
relationship: opposite_to BSPO:0000062 ! distal side
relationship: starts_axis BSPO:0000015 ! proximal-distal axis

[Term]
id: BSPO:0000062
name: distal side
namespace: spatial
def: "Anatomical side that is distally located on an organism or structure." [BSPO:wd]
synonym: "distal" EXACT []
xref: FBcv:0000058
xref: FBql:00005853
is_a: BSPO:0000054 ! anatomical side
relationship: distal_to BSPO:0000061 ! proximal side
relationship: finishes_axis BSPO:0000015 ! proximal-distal axis

[Term]
id: BSPO:0000063
name: dorsal side
namespace: spatial
def: "An anatomical region that is the entire part of an anatomical structure dorsal to a horizontal plane and bounded on one side by the same transverse plane." [BSPO:wd]
synonym: "dorsal" EXACT []
xref: FBcv:0000059
xref: FBql:00005842
is_a: BSPO:0000054 ! anatomical side
relationship: dorsal_to BSPO:0000066 ! lateral side
relationship: opposite_to BSPO:0000068 ! ventral side
relationship: starts_axis BSPO:0000016 ! dorsal-ventral axis

[Term]
id: BSPO:0000064
name: postero-medial region
namespace: spatial
def: "Anatomical region that overlaps the posterior and medial regions of the body or body part." [BSPO:wd]
synonym: "posteromedial region" EXACT []
is_a: BSPO:0000072 ! posterior region
is_a: BSPO:0000083 ! medial region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000056 ! posterior side
intersection_of: overlaps BSPO:0000067 ! medial side
created_by: Melissa  Haendel
creation_date: 2009-09-10T08:56:39Z

[Term]
id: BSPO:0000066
name: lateral side
namespace: spatial
synonym: "lateral" EXACT []
xref: FBcv:0000063
xref: FBql:00005844
is_a: BSPO:0000054 ! anatomical side

[Term]
id: BSPO:0000067
name: medial side
namespace: spatial
comment: a point in the centre of the organism (where the left-right axis intersects the midsagittal plane)
synonym: "medial" EXACT []
xref: FBcv:0000064
xref: FBql:00005847
is_a: BSPO:0000054 ! anatomical side

[Term]
id: BSPO:0000068
name: ventral side
namespace: spatial
def: "An anatomical region that is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane." [BSPO:RW, BSPO:wd]
synonym: "ventral" EXACT []
xref: FBcv:0000070
xref: FBql:00005843
is_a: BSPO:0000054 ! anatomical side
relationship: finishes_axis BSPO:0000016 ! dorsal-ventral axis

[Term]
id: BSPO:0000069
name: dorso-medial region
namespace: spatial
def: "Anatomical region that overlaps the dorsal and medial regions of the body or body part." [BSPO:wd]
synonym: "dorsomedial region" EXACT []
is_a: BSPO:0000079 ! dorsal region
is_a: BSPO:0000083 ! medial region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000063 ! dorsal side
intersection_of: overlaps BSPO:0000067 ! medial side
created_by: Melissa  Haendel
creation_date: 2009-09-10T08:57:22Z

[Term]
id: BSPO:0000070
name: anatomical region
namespace: spatial
def: "A 3D region in space without well-defined compartmental boundaries; for example, the dorsal region of an ectoderm." [BSPO:cjm]
comment: to be merged into CARO
xref: FBql:00005841
is_a: CARO:0000003 ! connected anatomical structure

[Term]
id: BSPO:0000071
name: anterior region
namespace: spatial
def: "Anatomical region anteriorly located on the body or body part." [BSPO:wd]
xref: FBql:00005848
is_a: BSPO:0000070 ! anatomical region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000055 ! anterior side
relationship: overlaps BSPO:0000055 ! anterior side

[Term]
id: BSPO:0000072
name: posterior region
namespace: spatial
def: "Anatomical region posteriorly located on the body or body part." [BSPO:wd]
xref: FBql:00005849
is_a: BSPO:0000070 ! anatomical region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000056 ! posterior side
relationship: overlaps BSPO:0000056 ! posterior side

[Term]
id: BSPO:0000077
name: proximal region
namespace: spatial
def: "Anatomical region proximally located on the body or body part." [BSPO:wd]
xref: FBql:00005852
is_a: BSPO:0000070 ! anatomical region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000061 ! proximal side
relationship: overlaps BSPO:0000061 ! proximal side

[Term]
id: BSPO:0000078
name: distal region
namespace: spatial
def: "Anatomical region distally located on the body or body part." [BSPO:wd]
xref: FBql:00005853
is_a: BSPO:0000070 ! anatomical region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000062 ! distal side
relationship: overlaps BSPO:0000062 ! distal side

[Term]
id: BSPO:0000079
name: dorsal region
namespace: spatial
def: "Anatomical region dorsally located on the body or body part." [BSPO:wd]
xref: FBql:00005842
is_a: BSPO:0000070 ! anatomical region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000063 ! dorsal side
relationship: overlaps BSPO:0000063 ! dorsal side

[Term]
id: BSPO:0000080
name: dorso-lateral region
namespace: spatial
def: "Anatomical region that overlaps the dorsal and lateral regions of a body or body part." [BSPO:wd]
synonym: "dorsolateral region" EXACT []
xref: FBql:00005845
is_a: BSPO:0000079 ! dorsal region
is_a: BSPO:0000082 ! lateral region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000063 ! dorsal side
intersection_of: overlaps BSPO:0000066 ! lateral side

[Term]
id: BSPO:0000082
name: lateral region
namespace: spatial
def: "Anatomical region laterally located on the body or body part." [BSPO:wd]
xref: FBql:00005844
is_a: BSPO:0000070 ! anatomical region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000066 ! lateral side
relationship: overlaps BSPO:0000066 ! lateral side

[Term]
id: BSPO:0000083
name: medial region
namespace: spatial
def: "Anatomical region medially located on the body or body part." [BSPO:wd]
xref: FBql:00005847
is_a: BSPO:0000070 ! anatomical region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000067 ! medial side
relationship: overlaps BSPO:0000067 ! medial side

[Term]
id: BSPO:0000084
name: ventral region
namespace: spatial
def: "Anatomical region ventrally located on the body or body part." [BSPO:wd]
xref: FBql:00005843
is_a: BSPO:0000070 ! anatomical region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000068 ! ventral side
relationship: overlaps BSPO:0000068 ! ventral side

[Term]
id: BSPO:0000085
name: ventro-lateral region
namespace: spatial
def: "Anatomical region that overlaps the ventral and lateral regions of a body or body part." [BSPO:wd]
comment: This is an example of a composition of two axis positions.
synonym: "ventrolateral region" EXACT []
xref: FBql:00005846
is_a: BSPO:0000082 ! lateral region
is_a: BSPO:0000084 ! ventral region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000066 ! lateral side
intersection_of: overlaps BSPO:0000068 ! ventral side

[Term]
id: BSPO:0000112
name: ventro-medial region
namespace: spatial
def: "The region corresponding to the ventral region of the entity, towards the midline." [BSPO:wd]
synonym: "medioventral region" EXACT []
synonym: "ventromedial region" EXACT []
is_a: BSPO:0000083 ! medial region
is_a: BSPO:0000084 ! ventral region
intersection_of: BSPO:0000070 ! anatomical region
intersection_of: overlaps BSPO:0000067 ! medial side
intersection_of: overlaps BSPO:0000068 ! ventral side
created_by: Melissa  Haendel
creation_date: 2009-09-10T08:57:54Z

[Term]
id: BSPO:0000371
name: anterior surface
namespace: spatial
def: "Anatomical surface that is located on the anterior side of the body or body part." [BSPO:wd]
xref: FBql:00005848
is_a: BSPO:0000005 ! anatomical surface
intersection_of: BSPO:0000005 ! anatomical surface
intersection_of: surface_of BSPO:0000055 ! anterior side
relationship: surface_of BSPO:0000055 ! anterior side

[Term]
id: BSPO:0000372
name: posterior surface
namespace: spatial
def: "Anatomical surface that is located on the posterior side of the body or body part." [BSPO:wd]
xref: FBql:00005849
is_a: BSPO:0000005 ! anatomical surface
intersection_of: BSPO:0000005 ! anatomical surface
intersection_of: surface_of BSPO:0000056 ! posterior side
relationship: surface_of BSPO:0000056 ! posterior side

[Term]
id: BSPO:0000377
name: internal side
name: proximal surface
namespace: spatial
def: "Anatomical surface that is located on the proximal side of the body or body part." [BSPO:wd]
xref: FBql:00005852
is_a: BSPO:0000005 ! anatomical surface
intersection_of: BSPO:0000005 ! anatomical surface
intersection_of: surface_of BSPO:0000061 ! proximal side
relationship: opposite_to BSPO:0000378 ! distal surface
relationship: surface_of BSPO:0000061 ! proximal side

[Term]
id: BSPO:0000378
name: distal surface
name: external side
namespace: spatial
def: "Anatomical surface that is located on the distal side of the body or body part." [BSPO:wd]
xref: FBql:00005853
is_a: BSPO:0000005 ! anatomical surface
intersection_of: BSPO:0000005 ! anatomical surface
intersection_of: surface_of BSPO:0000062 ! distal side
relationship: opposite_to BSPO:0000377 ! internal side
relationship: surface_of BSPO:0000062 ! distal side

[Term]
id: BSPO:0000379
name: dorsal surface
namespace: spatial
def: "Anatomical surface that located on the dorsal side of the body or body part." [BSPO:wd]
xref: FBql:00005842
is_a: BSPO:0000005 ! anatomical surface
intersection_of: BSPO:0000005 ! anatomical surface
intersection_of: surface_of BSPO:0000063 ! dorsal side
relationship: surface_of BSPO:0000063 ! dorsal side

[Term]
id: BSPO:0000382
name: lateral surface
namespace: spatial
def: "Anatomical surface that located on the lateral side of the body or body part." [BSPO:wd]
xref: FBql:00005844
is_a: BSPO:0000005 ! anatomical surface
intersection_of: BSPO:0000005 ! anatomical surface
intersection_of: surface_of BSPO:0000066 ! lateral side
relationship: surface_of BSPO:0000066 ! lateral side

[Term]
id: BSPO:0000383
name: medial surface
namespace: spatial
def: "Anatomical surface that located on the medial side of the body or body part." [BSPO:wd]
xref: FBql:00005847
is_a: BSPO:0000005 ! anatomical surface
intersection_of: BSPO:0000005 ! anatomical surface
intersection_of: surface_of BSPO:0000067 ! medial side
relationship: surface_of BSPO:0000067 ! medial side

[Term]
id: BSPO:0000384
name: ventral surface
namespace: spatial
def: "Anatomical surface that is located on the ventral side of the body or body part." [BSPO:wd]
xref: FBql:00005843
is_a: BSPO:0000005 ! anatomical surface
intersection_of: BSPO:0000005 ! anatomical surface
intersection_of: surface_of BSPO:0000068 ! ventral side
relationship: surface_of BSPO:0000068 ! ventral side

[Term]
id: BSPO:0000400
name: anatomical plane
namespace: spatial
def: "A flat 2D plane intersecting an anatomical continuant, dividing it into two adjacent portions." [BSPO:cjm]
comment: These anatomical sections are applicable to most bilaterally symmetrical animals, but bipedal animals such as humans have more complex usage of these terms. For example, in post-embryonic humans a coronal plane is vertical and a transverse plane is horizontal, but for embryos and quadrupeds a coronal plane is horizontal and a transverse plane is vertical.
synonym: "anatomical cross-section" EXACT []
synonym: "anatomical section" EXACT []
synonym: "cross-section" RELATED []
synonym: "plane" EXACT []
synonym: "section" EXACT []
xref: FMA:242982
is_a: CARO:0000010 ! anatomical boundary

[Term]
id: BSPO:0000417
name: sagittal plane
namespace: spatial
def: "Anatomical plane that divides a bilateral body into left and right parts, not necessarily of even size." [BSPO:cjm, BSPO:DOS, BSPO:mah]
synonym: "left/right plane" EXACT []
synonym: "median plane" EXACT []
synonym: "sagittal section" EXACT []
xref: FMA:11361
is_a: BSPO:0000010 ! anatomical axis
is_a: BSPO:0000400 ! anatomical plane
intersection_of: BSPO:0000400 ! anatomical plane
intersection_of: BSPO:0001102 BSPO:0000013 ! parallel to anterior-posterior axis
intersection_of: BSPO:0001102 BSPO:0000016 ! parallel to dorsal-ventral axis
intersection_of: orthogonal_to BSPO:0000017 ! left-right axis
relationship: BSPO:0001102 BSPO:0000013 ! parallel to anterior-posterior axis
relationship: BSPO:0001102 BSPO:0000016 ! parallel to dorsal-ventral axis
relationship: orthogonal_to BSPO:0000017 ! left-right axis

[Term]
id: BSPO:0000671
name: anterior margin
namespace: spatial
def: "Anatomical margin that is located on the anterior side of a body or body part." [BSPO:wd]
is_a: BSPO:0000006 ! anatomical margin
is_a: BSPO:0000071 ! anterior region
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000055 ! anterior side

[Term]
id: BSPO:0000672
name: posterior margin
namespace: spatial
def: "Anatomical margin that is located on the posterior side of the body or body part." [BSPO:wd]
is_a: BSPO:0000006 ! anatomical margin
is_a: BSPO:0000072 ! posterior region
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000056 ! posterior side

[Term]
id: BSPO:0000677
name: proximal margin
namespace: spatial
def: "Anatomical margin that is located on the proximal region of the body or body part." [BSPO:wd]
is_a: BSPO:0000006 ! anatomical margin
is_a: BSPO:0000077 ! proximal region
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000061 ! proximal side

[Term]
id: BSPO:0000678
name: distal margin
namespace: spatial
def: "Anatomical margin that is located on the distal side of the body or body part." [BSPO:wd]
is_a: BSPO:0000006 ! anatomical margin
is_a: BSPO:0000078 ! distal region
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000062 ! distal side

[Term]
id: BSPO:0000679
name: dorsal margin
namespace: spatial
def: "Anatomical margin that is located on the dorsal side of body or body part." [BSPO:wd]
is_a: BSPO:0000006 ! anatomical margin
is_a: BSPO:0000079 ! dorsal region
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000063 ! dorsal side

[Term]
id: BSPO:0000680
name: dorso-lateral margin
namespace: spatial
def: "Anatomical margin that is located on the dorso-lateral region of the body or body part." [BSPO:wd]
synonym: "dorsolateral margin" EXACT []
is_a: BSPO:0000080 ! dorso-lateral region
is_a: BSPO:0000679 ! dorsal margin
is_a: BSPO:0000682 ! lateral margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000063 ! dorsal side
intersection_of: overlaps BSPO:0000066 ! lateral side

[Term]
id: BSPO:0000682
name: lateral margin
namespace: spatial
def: "Anatomical margin that is located on the lateral side of the body or body part." [BSPO:wd]
is_a: BSPO:0000006 ! anatomical margin
is_a: BSPO:0000082 ! lateral region
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000066 ! lateral side

[Term]
id: BSPO:0000683
name: medial margin
namespace: spatial
def: "Anatomical margin that is located on the medial side of the body or body part." [BSPO:wd]
is_a: BSPO:0000006 ! anatomical margin
is_a: BSPO:0000083 ! medial region
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000067 ! medial side

[Term]
id: BSPO:0000684
name: ventral margin
namespace: spatial
def: "Anatomical margin that is located on the ventral side of the body or body part." [BSPO:wd]
is_a: BSPO:0000006 ! anatomical margin
is_a: BSPO:0000084 ! ventral region
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000068 ! ventral side

[Term]
id: BSPO:0000685
name: ventro-lateral margin
namespace: spatial
def: "Anatomical margin that is located on the ventro-lateral region of the body or body part." [BSPO:wd]
comment: This is an example of a composition of two axis positions
synonym: "ventrolateral margin" EXACT []
is_a: BSPO:0000085 ! ventro-lateral region
is_a: BSPO:0000682 ! lateral margin
is_a: BSPO:0000684 ! ventral margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000066 ! lateral side
intersection_of: overlaps BSPO:0000068 ! ventral side

[Term]
id: BSPO:0000686
name: antero-dorsal margin
namespace: spatial
def: "Anatomical margin that is located on the antero-dorso region of the body or body part." [BSPO:wd]
synonym: "anterodorsal margin" EXACT []
is_a: BSPO:0000026 ! antero-dorsal region
is_a: BSPO:0000671 ! anterior margin
is_a: BSPO:0000679 ! dorsal margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000055 ! anterior side
intersection_of: overlaps BSPO:0000063 ! dorsal side

[Term]
id: BSPO:0000687
name: postero-dorsal margin
namespace: spatial
def: "Anatomical margin that is located on the postero-dorsal region of the body or body part." [BSPO:wd]
synonym: "posterodorsal margin" EXACT []
is_a: BSPO:0000030 ! postero-dorsal region
is_a: BSPO:0000672 ! posterior margin
is_a: BSPO:0000679 ! dorsal margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000056 ! posterior side
intersection_of: overlaps BSPO:0000063 ! dorsal side

[Term]
id: BSPO:0000688
name: antero-ventral margin
namespace: spatial
def: "Anatomical margin that is located on the antero-ventral region of the body or body part." [BSPO:wd]
synonym: "anteroventral margin" EXACT []
is_a: BSPO:0000027 ! antero-ventral region
is_a: BSPO:0000671 ! anterior margin
is_a: BSPO:0000684 ! ventral margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000055 ! anterior side
intersection_of: overlaps BSPO:0000068 ! ventral side

[Term]
id: BSPO:0000689
name: postero-ventral margin
namespace: spatial
def: "Anatomical margin that is located on the postero-ventral region of the body or body part." [BSPO:wd]
synonym: "posteroventral margin" EXACT []
is_a: BSPO:0000035 ! postero-ventral region
is_a: BSPO:0000672 ! posterior margin
is_a: BSPO:0000684 ! ventral margin
intersection_of: BSPO:0000006 ! anatomical margin
intersection_of: overlaps BSPO:0000056 ! posterior side
intersection_of: overlaps BSPO:0000068 ! ventral side

[Term]
id: CARO:0000000
name: anatomical entity
namespace: spatial
def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex.  Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [CAROC:Brownsville2014]
def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [CARO:MAH]
comment: Following BFO, material anatomical entities may have immaterial parts (the lumen of your stomach is part of your stomach).  The granularity limit follows the limits set by the Gene Ontology on the granularity limit for GO:cellular_component. Note that substances produced by an organism (sweat, feaces, urine) do not need to be part of an organism to qualify as an anatomical structure.
is_a: BFO:0000004 ! independent continuant

[Term]
id: CARO:0000003
name: anatomical structure
name: connected anatomical structure
namespace: spatial
def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CC:DOS]
comment: Note that the definition does not say 'generated exclusively by the co-ordinated expression of the organism's own genome', so this is still valid for cases where normal morphogenesis requires the actions of a facultative symbiont, or some looser dependency such as the a requirement for the presence of gut flora for normal gut development.
is_a: CARO:0000006 ! material anatomical entity

[Term]
id: CARO:0000006
name: material anatomical entity
namespace: spatial
def: "An anatomical entity that has mass." [CC:DOS]
is_a: CARO:0000000 ! anatomical entity
disjoint_from: CARO:0000007 ! immaterial anatomical entity

[Term]
id: CARO:0000007
name: immaterial anatomical entity
namespace: spatial
def: "An anatomical entity that has no mass." [CC:DOS]
def: "Anatomical entity that has no mass." []
is_a: BFO:0000141 ! immaterial entity
is_a: CARO:0000000 ! anatomical entity

[Term]
id: CARO:0000008
name: anatomical line
namespace: spatial
def: "A one dimensional, immaterial anatomical entity." [CC:DOS]
is_a: CARO:0000007 ! immaterial anatomical entity

[Term]
id: CARO:0000010
name: anatomical boundary
namespace: spatial
def: "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." [CC:DOS]
is_a: CARO:0000007 ! immaterial anatomical entity

[Term]
id: CHEBI:10545
name: electron
namespace: chebi_ontology
def: "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." []
subset: 3_STAR
synonym: "beta" RELATED [IUPAC]
synonym: "beta(-)" RELATED [ChEBI]
synonym: "beta-particle" RELATED [IUPAC]
synonym: "e" RELATED [IUPAC]
synonym: "e(-)" RELATED [UniProt]
synonym: "e-" RELATED [KEGG_COMPOUND]
synonym: "electron" EXACT [KEGG_COMPOUND]
synonym: "electron" EXACT IUPAC_NAME [IUPAC]
synonym: "electron" EXACT [ChEBI]
synonym: "Elektron" RELATED [ChEBI]
synonym: "negatron" RELATED [IUPAC]
xref: KEGG:C05359
xref: PMID:21614077 {source="Europe PMC"}
xref: Wikipedia:Electron
is_a: CHEBI:36338 ! lepton
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "0.000548579903" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "0.0" xsd:string

[Term]
id: CHEBI:131927
name: dicarboxylic acids and O-substituted derivatives
namespace: chebi_ontology
def: "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." []
subset: 3_STAR
synonym: "dicarboxylic acids and derivatives" RELATED [ChEBI]
is_a: CHEBI:36586 ! carbonyl compound

[Term]
id: CHEBI:132153
name: hyaluronate
namespace: chebi_ontology
def: "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." []
subset: 3_STAR
synonym: "hyaluronan" RELATED [UniProt]
synonym: "hyaluronate polyanion" RELATED [ChEBI]
is_a: CHEBI:61469 ! polyanionic polymer
is_a: CHEBI:63551 ! carbohydrate acid derivative anion
relationship: is_conjugate_base_of CHEBI:16336 ! hyaluronic acid
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "(C14H20NO11)n.H2O" xsd:string

[Term]
id: CHEBI:136889
name: 5beta steroid
namespace: chebi_ontology
def: "Any steroid that has beta-configuration at position 5." []
subset: 3_STAR
synonym: "5beta steroids" RELATED [ChEBI]
synonym: "5beta-steroid" RELATED [ChEBI]
synonym: "5beta-steroids" RELATED [ChEBI]
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:138103
name: inorganic acid
namespace: chebi_ontology
def: "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." []
subset: 3_STAR
synonym: "inorganic acids" RELATED [ChEBI]
synonym: "mineral acid" RELATED [ChEBI]
synonym: "mineral acids" RELATED [ChEBI]
xref: Wikipedia:Mineral_acid
is_a: CHEBI:39141 ! Bronsted acid

[Term]
id: CHEBI:138366
name: bile acids
namespace: chebi_ontology
def: "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration." []
subset: 3_STAR
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35350 ! hydroxy steroid
is_a: CHEBI:36078 ! cholanoid

[Term]
id: CHEBI:138675
name: gas molecular entity
namespace: chebi_ontology
def: "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." []
subset: 3_STAR
synonym: "gas molecular entities" RELATED [ChEBI]
synonym: "gaseous molecular entities" RELATED [ChEBI]
synonym: "gaseous molecular entity" RELATED [ChEBI]
xref: Wikipedia:https\://en.wikipedia.org/wiki/Gas
is_a: CHEBI:33579 ! main group molecular entity

[Term]
id: CHEBI:13941
name: carbamate
namespace: chebi_ontology
subset: 3_STAR
synonym: "Carbamat" RELATED [ChEBI]
synonym: "carbamate" EXACT [UniProt]
synonym: "carbamate" EXACT IUPAC_NAME [IUPAC]
synonym: "carbamate ion" RELATED [ChemIDplus]
synonym: "carbamic acid, ion(1-)" RELATED [ChemIDplus]
synonym: "Karbamat" RELATED [ChEBI]
xref: Beilstein:3903503 {source="Beilstein"}
xref: CAS:302-11-4 {source="ChemIDplus"}
xref: Gmelin:239604 {source="Gmelin"}
is_a: CHEBI:37022 ! amino-acid anion
relationship: is_conjugate_base_of CHEBI:28616 ! carbamic acid
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2NO2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-M" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "60.03212" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.00910" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC([O-])=O" xsd:string

[Term]
id: CHEBI:142163
name: 24G7 epitope
namespace: chebi_ontology
def: "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22." []
subset: 3_STAR
is_a: CHEBI:24433 ! group
relationship: has_role CHEBI:53000 ! epitope
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C7H6N2O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "134.136" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "134.04801" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(=CC(NC(=*)*)=*)(NC(C(C)=*)=O)*" xsd:string

[Term]
id: CHEBI:15339
name: acceptor
namespace: chebi_ontology
alt_id: CHEBI:13699
alt_id: CHEBI:2377
def: "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." []
subset: 3_STAR
synonym: "A" RELATED [KEGG_COMPOUND]
synonym: "accepteur" RELATED [ChEBI]
synonym: "Acceptor" EXACT [KEGG_COMPOUND]
synonym: "Akzeptor" RELATED [ChEBI]
synonym: "Hydrogen-acceptor" RELATED [KEGG_COMPOUND]
synonym: "Oxidized donor" RELATED [KEGG_COMPOUND]
xref: KEGG:C00028
xref: KEGG:C16722
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:15355
name: acetylcholine
namespace: chebi_ontology
alt_id: CHEBI:12686
alt_id: CHEBI:13715
alt_id: CHEBI:22197
alt_id: CHEBI:2416
alt_id: CHEBI:40559
def: "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." []
subset: 3_STAR
synonym: "2-acetyloxy-N,N,N-trimethylethanaminium" EXACT IUPAC_NAME [IUPAC]
synonym: "ACETYLCHOLINE" EXACT [PDBeChem]
synonym: "Acetylcholine" EXACT [KEGG_COMPOUND]
synonym: "acetylcholine" EXACT [UniProt]
synonym: "ACh" RELATED [ChemIDplus]
synonym: "Azetylcholin" RELATED [ChEBI]
synonym: "choline acetate" RELATED [ChemIDplus]
synonym: "O-Acetylcholine" RELATED [KEGG_COMPOUND]
xref: Beilstein:1764436 {source="ChemIDplus"}
xref: CAS:51-84-3 {source="KEGG COMPOUND"}
xref: CAS:51-84-3 {source="ChemIDplus"}
xref: Drug_Central:65 {source="DrugCentral"}
xref: DrugBank:DB03128
xref: Gmelin:326108 {source="Gmelin"}
xref: KEGG:C01996
xref: LINCS:LSM-5888
xref: PDBeChem:ACH
xref: PMID:14764638 {source="Europe PMC"}
xref: PMID:15014918 {source="Europe PMC"}
xref: PMID:15231705 {source="Europe PMC"}
xref: PMID:15361288 {source="Europe PMC"}
xref: PMID:18050502 {source="Europe PMC"}
xref: PMID:18407448 {source="Europe PMC"}
xref: PMID:19255787 {source="Europe PMC"}
xref: PMID:20963497 {source="Europe PMC"}
xref: PMID:21130809 {source="Europe PMC"}
xref: PMID:21246223 {source="Europe PMC"}
xref: PMID:21545631 {source="Europe PMC"}
xref: PMID:21601579 {source="Europe PMC"}
xref: Wikipedia:Acetylcholine
is_a: CHEBI:35287 ! acylcholine
is_a: CHEBI:47622 ! acetate ester
relationship: has_role CHEBI:24621 ! hormone
relationship: has_role CHEBI:25512 ! neurotransmitter
relationship: has_role CHEBI:35620 ! vasodilator agent
relationship: has_role CHEBI:38325 ! muscarinic agonist
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: has_role CHEBI:77746 ! human metabolite
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C7H16NO2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OIPILFWXSMYKGL-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "146.20748" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "146.11756" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(=O)OCC[N+](C)(C)C" xsd:string

[Term]
id: CHEBI:15366
name: acetic acid
namespace: chebi_ontology
alt_id: CHEBI:22169
alt_id: CHEBI:2387
alt_id: CHEBI:40486
def: "A simple monocarboxylic acid containing two carbons." []
subset: 3_STAR
synonym: "ACETIC ACID" EXACT [PDBeChem]
synonym: "Acetic acid" EXACT [KEGG_COMPOUND]
synonym: "acetic acid" EXACT IUPAC_NAME [IUPAC]
synonym: "acide acetique" RELATED [ChemIDplus]
synonym: "AcOH" RELATED [ChEBI]
synonym: "CH3-COOH" RELATED [IUPAC]
synonym: "CH3CO2H" RELATED [ChEBI]
synonym: "E 260" RELATED [ChEBI]
synonym: "E-260" RELATED [ChEBI]
synonym: "E260" RELATED [ChEBI]
synonym: "Essigsaeure" RELATED [ChEBI]
synonym: "Ethanoic acid" RELATED [KEGG_COMPOUND]
synonym: "ethoic acid" RELATED [ChEBI]
synonym: "Ethylic acid" RELATED [ChemIDplus]
synonym: "HOAc" RELATED [ChEBI]
synonym: "INS No. 260" RELATED [ChEBI]
synonym: "MeCO2H" RELATED [ChEBI]
synonym: "MeCOOH" RELATED [ChEBI]
synonym: "Methanecarboxylic acid" RELATED [ChemIDplus]
xref: Beilstein:506007 {source="Beilstein"}
xref: CAS:64-19-7 {source="ChemIDplus"}
xref: CAS:64-19-7 {source="NIST Chemistry WebBook"}
xref: CAS:64-19-7 {source="KEGG COMPOUND"}
xref: Drug_Central:4211 {source="DrugCentral"}
xref: Gmelin:1380 {source="Gmelin"}
xref: HMDB:HMDB0000042
xref: KEGG:C00033
xref: KEGG:D00010
xref: KNApSAcK:C00001176
xref: LIPID_MAPS_instance:LMFA01010002 {source="LIPID MAPS"}
xref: MetaCyc:ACET
xref: PDBeChem:ACT
xref: PDBeChem:ACY
xref: PMID:12005138 {source="Europe PMC"}
xref: PMID:15107950 {source="Europe PMC"}
xref: PMID:16630552 {source="Europe PMC"}
xref: PMID:16774200 {source="Europe PMC"}
xref: PMID:17190852 {source="Europe PMC"}
xref: PMID:19416101 {source="Europe PMC"}
xref: PMID:19469536 {source="Europe PMC"}
xref: PMID:22153255 {source="Europe PMC"}
xref: PMID:22173419 {source="Europe PMC"}
xref: PPDB:1333
xref: Reaxys:506007 {source="Reaxys"}
xref: Wikipedia:Acetic_acid
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: has_role CHEBI:48356 ! protic solvent
relationship: has_role CHEBI:64049 ! food acidity regulator
relationship: has_role CHEBI:65256 ! antimicrobial food preservative
relationship: has_role CHEBI:83056 ! Daphnia magna metabolite
relationship: is_conjugate_acid_of CHEBI:30089 ! acetate
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4O2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "60.05200" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.02113" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(O)=O" xsd:string

[Term]
id: CHEBI:15379
name: dioxygen
namespace: chebi_ontology
alt_id: CHEBI:10745
alt_id: CHEBI:13416
alt_id: CHEBI:23833
alt_id: CHEBI:25366
alt_id: CHEBI:30491
alt_id: CHEBI:44742
alt_id: CHEBI:7860
subset: 3_STAR
synonym: "[OO]" RELATED [MolBase]
synonym: "dioxygen" EXACT IUPAC_NAME [IUPAC]
synonym: "dioxygene" RELATED [ChEBI]
synonym: "Disauerstoff" RELATED [ChEBI]
synonym: "E 948" RELATED [ChEBI]
synonym: "E-948" RELATED [ChEBI]
synonym: "E948" RELATED [ChEBI]
synonym: "molecular oxygen" RELATED [ChEBI]
synonym: "O2" RELATED [UniProt]
synonym: "O2" RELATED [IUPAC]
synonym: "O2" RELATED [KEGG_COMPOUND]
synonym: "Oxygen" RELATED [KEGG_COMPOUND]
synonym: "OXYGEN MOLECULE" RELATED [PDBeChem]
xref: CAS:7782-44-7 {source="NIST Chemistry WebBook"}
xref: CAS:7782-44-7 {source="ChemIDplus"}
xref: CAS:7782-44-7 {source="KEGG COMPOUND"}
xref: Gmelin:485 {source="Gmelin"}
xref: HMDB:HMDB0001377
xref: KEGG:C00007
xref: KEGG:D00003
xref: MetaCyc:OXYGEN-MOLECULE
xref: MolBase:750
xref: PDBeChem:OXY
xref: PMID:10906528 {source="Europe PMC"}
xref: PMID:16977326 {source="Europe PMC"}
xref: PMID:18210929 {source="Europe PMC"}
xref: PMID:18638417 {source="Europe PMC"}
xref: PMID:19840863 {source="Europe PMC"}
xref: PMID:7710549 {source="Europe PMC"}
xref: PMID:9463773 {source="Europe PMC"}
xref: Wikipedia:Oxygen
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:25362 ! elemental molecule
is_a: CHEBI:33263 ! diatomic oxygen
relationship: has_role CHEBI:27027 ! micronutrient
relationship: has_role CHEBI:33893 ! reagent
relationship: has_role CHEBI:35472 ! anti-inflammatory drug
relationship: has_role CHEBI:63248 ! oxidising agent
relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite
relationship: has_role CHEBI:77746 ! human metabolite
relationship: has_role CHEBI:77974 ! food packaging gas
relationship: is_conjugate_base_of CHEBI:29793 ! hydridodioxygen(1+)
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "O2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O2/c1-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MYMOFIZGZYHOMD-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "31.998" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.98983" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=O" xsd:string

[Term]
id: CHEBI:15693
name: aldose
namespace: chebi_ontology
alt_id: CHEBI:13755
alt_id: CHEBI:22305
alt_id: CHEBI:2561
def: "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals." []
subset: 3_STAR
synonym: "Aldose" EXACT [KEGG_COMPOUND]
synonym: "aldoses" RELATED [ChEBI]
synonym: "an aldose" RELATED [UniProt]
xref: KEGG:C01370
xref: Wikipedia:Aldose
is_a: CHEBI:35381 ! monosaccharide
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4O2(CH2O)n" xsd:string

[Term]
id: CHEBI:15841
name: polypeptide
namespace: chebi_ontology
alt_id: CHEBI:14860
alt_id: CHEBI:8314
def: "A peptide containing ten or more amino acid residues." []
subset: 3_STAR
synonym: "polipeptido" RELATED [ChEBI]
synonym: "Polypeptid" RELATED [ChEBI]
synonym: "Polypeptide" EXACT [KEGG_COMPOUND]
synonym: "polypeptides" EXACT IUPAC_NAME [IUPAC]
xref: KEGG:C00403
is_a: CHEBI:16670 ! peptide
is_a: CHEBI:33839 ! macromolecule
property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H6N2O3R2(C2H2NOR)n" xsd:string

[Term]
id: CHEBI:15986
name: polynucleotide
namespace: chebi_ontology
alt_id: CHEBI:13672
alt_id: CHEBI:14859
alt_id: CHEBI:8312
def: "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." []
subset: 3_STAR
synonym: "Polynucleotide" EXACT [KEGG_COMPOUND]
synonym: "polynucleotides" RELATED [ChEBI]
xref: KEGG:C00419
is_a: CHEBI:33695 ! information biomacromolecule
is_a: CHEBI:61120 ! nucleobase-containing molecular entity
relationship: has_part CHEBI:50319 ! nucleotide residue
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "(C5H8O6PR)n.C10H17O10PR2" xsd:string

[Term]
id: CHEBI:16134
name: ammonia
namespace: chebi_ontology
alt_id: CHEBI:13405
alt_id: CHEBI:13406
alt_id: CHEBI:13407
alt_id: CHEBI:13771
alt_id: CHEBI:22533
alt_id: CHEBI:44269
alt_id: CHEBI:44284
alt_id: CHEBI:44404
alt_id: CHEBI:7434
def: "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." []
subset: 3_STAR
synonym: "[NH3]" RELATED [MolBase]
synonym: "AMMONIA" EXACT [PDBeChem]
synonym: "Ammonia" EXACT [KEGG_COMPOUND]
synonym: "ammonia" EXACT IUPAC_NAME [IUPAC]
synonym: "ammoniac" RELATED [ChEBI]
synonym: "Ammoniak" RELATED [ChemIDplus]
synonym: "amoniaco" RELATED [ChEBI]
synonym: "azane" EXACT IUPAC_NAME [IUPAC]
synonym: "NH3" RELATED [KEGG_COMPOUND]
synonym: "NH3" RELATED [UniProt]
synonym: "NH3" RELATED [IUPAC]
synonym: "R-717" RELATED [ChEBI]
synonym: "spirit of hartshorn" RELATED [ChemIDplus]
xref: Beilstein:3587154 {source="Beilstein"}
xref: CAS:7664-41-7 {source="ChemIDplus"}
xref: CAS:7664-41-7 {source="NIST Chemistry WebBook"}
xref: CAS:7664-41-7 {source="KEGG COMPOUND"}
xref: Drug_Central:4625 {source="DrugCentral"}
xref: Gmelin:79 {source="Gmelin"}
xref: HMDB:HMDB0000051
xref: KEGG:C00014
xref: KEGG:D02916
xref: KNApSAcK:C00007267
xref: MetaCyc:AMMONIA
xref: MolBase:930
xref: PDBeChem:NH3
xref: PMID:110589 {source="Europe PMC"}
xref: PMID:11139349 {source="Europe PMC"}
xref: PMID:11540049 {source="Europe PMC"}
xref: PMID:11746427 {source="Europe PMC"}
xref: PMID:11783653 {source="Europe PMC"}
xref: PMID:13753780 {source="Europe PMC"}
xref: PMID:14663195 {source="Europe PMC"}
xref: PMID:15092448 {source="Europe PMC"}
xref: PMID:15094021 {source="Europe PMC"}
xref: PMID:15554424 {source="Europe PMC"}
xref: PMID:15969015 {source="Europe PMC"}
xref: PMID:16008360 {source="Europe PMC"}
xref: PMID:16050680 {source="Europe PMC"}
xref: PMID:16348008 {source="Europe PMC"}
xref: PMID:16349403 {source="Europe PMC"}
xref: PMID:16614889 {source="Europe PMC"}
xref: PMID:16664306 {source="Europe PMC"}
xref: PMID:16842901 {source="Europe PMC"}
xref: PMID:17025297 {source="Europe PMC"}
xref: PMID:17439666 {source="Europe PMC"}
xref: PMID:17569513 {source="Europe PMC"}
xref: PMID:17737668 {source="Europe PMC"}
xref: PMID:18670398 {source="Europe PMC"}
xref: PMID:22002069 {source="Europe PMC"}
xref: PMID:22081570 {source="Europe PMC"}
xref: PMID:22088435 {source="Europe PMC"}
xref: PMID:22100291 {source="Europe PMC"}
xref: PMID:22130175 {source="Europe PMC"}
xref: PMID:22150211 {source="Europe PMC"}
xref: PMID:22240068 {source="Europe PMC"}
xref: PMID:22290316 {source="Europe PMC"}
xref: PMID:22342082 {source="Europe PMC"}
xref: PMID:22385337 {source="Europe PMC"}
xref: PMID:22443779 {source="Europe PMC"}
xref: PMID:22560242 {source="Europe PMC"}
xref: Reaxys:3587154 {source="Reaxys"}
xref: Wikipedia:Ammonia
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:35107 ! azane
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: has_role CHEBI:50910 ! neurotoxin
relationship: has_role CHEBI:59740 ! nucleophilic reagent
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: has_role CHEBI:77941 ! EC 3.5.1.4 (amidase) inhibitor
relationship: has_role CHEBI:78433 ! refrigerant
relationship: is_conjugate_acid_of CHEBI:29337 ! azanide
relationship: is_conjugate_base_of CHEBI:28938 ! ammonium
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "H3N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3N/h1H3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "17.03056" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.02655" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]N([H])[H]" xsd:string

[Term]
id: CHEBI:16189
name: sulfate
namespace: chebi_ontology
alt_id: CHEBI:15135
alt_id: CHEBI:45687
alt_id: CHEBI:9335
def: "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." []
subset: 3_STAR
synonym: "[SO4](2-)" RELATED [IUPAC]
synonym: "SO4(2-)" RELATED [IUPAC]
synonym: "Sulfate" EXACT [KEGG_COMPOUND]
synonym: "sulfate" EXACT [UniProt]
synonym: "sulfate" EXACT IUPAC_NAME [IUPAC]
synonym: "Sulfate anion(2-)" RELATED [HMDB]
synonym: "Sulfate dianion" RELATED [HMDB]
synonym: "SULFATE ION" RELATED [PDBeChem]
synonym: "Sulfate(2-)" RELATED [HMDB]
synonym: "Sulfuric acid ion(2-)" RELATED [HMDB]
synonym: "sulphate" RELATED [ChEBI]
synonym: "sulphate ion" RELATED [ChEBI]
synonym: "tetraoxidosulfate(2-)" EXACT IUPAC_NAME [IUPAC]
synonym: "tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC]
synonym: "tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC]
xref: Beilstein:3648446 {source="Beilstein"}
xref: CAS:14808-79-8 {source="ChemIDplus"}
xref: CAS:14808-79-8 {source="NIST Chemistry WebBook"}
xref: Gmelin:2120 {source="Gmelin"}
xref: HMDB:HMDB0001448
xref: KEGG:C00059
xref: KEGG:D05963
xref: MetaCyc:SULFATE
xref: PDBeChem:SO4
xref: PMID:11200094 {source="Europe PMC"}
xref: PMID:11452993 {source="Europe PMC"}
xref: PMID:11581495 {source="Europe PMC"}
xref: PMID:11798107 {source="Europe PMC"}
xref: PMID:12166931 {source="Europe PMC"}
xref: PMID:12668033 {source="Europe PMC"}
xref: PMID:14597181 {source="Europe PMC"}
xref: PMID:15093386 {source="Europe PMC"}
xref: PMID:15984785 {source="Europe PMC"}
xref: PMID:16186560 {source="Europe PMC"}
xref: PMID:16345535 {source="Europe PMC"}
xref: PMID:16347366 {source="Europe PMC"}
xref: PMID:16348007 {source="Europe PMC"}
xref: PMID:16483812 {source="Europe PMC"}
xref: PMID:16534979 {source="Europe PMC"}
xref: PMID:16656509 {source="Europe PMC"}
xref: PMID:16742508 {source="Europe PMC"}
xref: PMID:16742518 {source="Europe PMC"}
xref: PMID:17120760 {source="Europe PMC"}
xref: PMID:17420092 {source="Europe PMC"}
xref: PMID:17439666 {source="Europe PMC"}
xref: PMID:17709180 {source="Europe PMC"}
xref: PMID:18398178 {source="Europe PMC"}
xref: PMID:18815700 {source="Europe PMC"}
xref: PMID:18846414 {source="Europe PMC"}
xref: PMID:19047345 {source="Europe PMC"}
xref: PMID:19244483 {source="Europe PMC"}
xref: PMID:19544990 {source="Europe PMC"}
xref: PMID:19628332 {source="Europe PMC"}
xref: PMID:19812358 {source="Europe PMC"}
xref: PMID:30398859 {source="Europe PMC"}
xref: Reaxys:3648446 {source="Reaxys"}
xref: Wikipedia:Sulfate
is_a: CHEBI:33482 ! sulfur oxoanion
is_a: CHEBI:48154 ! sulfur oxide
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: has_role CHEBI:23357 ! cofactor
relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_base_of CHEBI:45696 ! hydrogensulfate
property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "O4S" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-L" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06360" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95283" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S([O-])(=O)=O" xsd:string

[Term]
id: CHEBI:16336
name: hyaluronic acid
namespace: chebi_ontology
alt_id: CHEBI:14412
alt_id: CHEBI:24622
alt_id: CHEBI:24623
alt_id: CHEBI:5772
def: "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells." []
subset: 3_STAR
synonym: "[beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n" RELATED [ChEBI]
synonym: "[beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n" RELATED [KEGG_COMPOUND]
synonym: "acide hyaluronique" RELATED [ChEBI]
synonym: "acido hialuronico" RELATED [ChEBI]
synonym: "hyaluronan" RELATED [ChEBI]
synonym: "Hyaluronic acid" EXACT [KEGG_COMPOUND]
synonym: "Hyaluronsaeure" RELATED [ChEBI]
xref: Beilstein:8538277 {source="Beilstein"}
xref: CAS:9004-61-9 {source="KEGG COMPOUND"}
xref: CAS:9004-61-9 {source="ChemIDplus"}
xref: HMDB:HMDB0010366
xref: KEGG:C00518
xref: KEGG:D08043
xref: KEGG:G10505
xref: PMID:11122186 {source="Europe PMC"}
xref: PMID:18056362 {source="Europe PMC"}
xref: PMID:18290544 {source="Europe PMC"}
xref: Reaxys:8187837 {source="Reaxys"}
xref: Wikipedia:Hyaluronan
is_a: CHEBI:37395 ! mucopolysaccharide
is_a: CHEBI:72813 ! exopolysaccharide
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_acid_of CHEBI:132153 ! hyaluronate
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "(C14H21NO12)n" xsd:string

[Term]
id: CHEBI:16541
name: protein polypeptide chain
namespace: chebi_ontology
alt_id: CHEBI:8526
def: "A naturally occurring polypeptide synthesized at the ribosome." []
subset: 3_STAR
synonym: "a protein" RELATED [UniProt]
synonym: "polypeptide chain" RELATED [ChEBI]
synonym: "Protein" RELATED [KEGG_COMPOUND]
synonym: "protein polypeptide chains" RELATED [ChEBI]
xref: KEGG:C00017
is_a: CHEBI:15841 ! polypeptide
relationship: has_part CHEBI:33700 ! proteinogenic amino-acid residue

[Term]
id: CHEBI:16646
name: carbohydrate
namespace: chebi_ontology
alt_id: CHEBI:15131
alt_id: CHEBI:23008
alt_id: CHEBI:9318
def: "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." []
subset: 3_STAR
synonym: "a carbohydrate" RELATED [UniProt]
synonym: "carbohidrato" RELATED [IUPAC]
synonym: "carbohidratos" RELATED [IUPAC]
synonym: "carbohydrate" EXACT IUPAC_NAME [IUPAC]
synonym: "carbohydrates" EXACT IUPAC_NAME [IUPAC]
synonym: "glucide" RELATED [ChEBI]
synonym: "glucides" RELATED [ChEBI]
synonym: "glucido" RELATED [ChEBI]
synonym: "glucidos" RELATED [ChEBI]
synonym: "hydrates de carbone" RELATED [ChEBI]
synonym: "Kohlenhydrat" RELATED [ChEBI]
synonym: "Kohlenhydrate" RELATED [ChEBI]
synonym: "saccharide" RELATED [IUPAC]
synonym: "saccharides" RELATED [IUPAC]
synonym: "saccharidum" RELATED [ChEBI]
xref: Wikipedia:Carbohydrate
is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives

[Term]
id: CHEBI:16670
name: peptide
namespace: chebi_ontology
alt_id: CHEBI:14753
alt_id: CHEBI:25906
alt_id: CHEBI:7990
def: "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." []
subset: 3_STAR
synonym: "Peptid" RELATED [ChEBI]
synonym: "Peptide" EXACT [KEGG_COMPOUND]
synonym: "peptides" EXACT IUPAC_NAME [IUPAC]
synonym: "peptido" RELATED [ChEBI]
synonym: "peptidos" RELATED [ChEBI]
xref: KEGG:C00012
is_a: CHEBI:37622 ! carboxamide
is_a: CHEBI:50047 ! organic amino compound
relationship: has_part CHEBI:33708 ! amino-acid residue
relationship: is_tautomer_of CHEBI:60466 ! peptide zwitterion
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "(C2H2NOR)nC2H3NOR" xsd:string

[Term]
id: CHEBI:166902
name: noradrenaline(1+)
namespace: chebi_ontology
subset: 2_STAR
synonym: "noradrenaline" RELATED [UniProt]
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: is_conjugate_acid_of CHEBI:33569 ! noradrenaline
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H12NO3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-UHFFFAOYSA-O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "170.187" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "170.08117" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=CC(=CC(=C1O)O)C(C[NH3+])O" xsd:string

[Term]
id: CHEBI:167559
name: glycan
namespace: chebi_ontology
def: "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." []
subset: 3_STAR
synonym: "glycans" RELATED [ChEBI]
is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives

[Term]
id: CHEBI:16765
name: tryptamine
namespace: chebi_ontology
alt_id: CHEBI:15274
alt_id: CHEBI:27161
alt_id: CHEBI:46157
alt_id: CHEBI:9767
def: "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." []
subset: 3_STAR
synonym: "1H-indole-3-ethanamine" RELATED [NIST_Chemistry_WebBook]
synonym: "2-(1H-INDOL-3-YL)ETHANAMINE" RELATED [PDBeChem]
synonym: "2-(1H-indol-3-yl)ethanamine" EXACT IUPAC_NAME [IUPAC]
synonym: "2-(3-indolyl)ethylamine" RELATED [ChemIDplus]
synonym: "3-(2-Aminoethyl)indole" RELATED [KEGG_COMPOUND]
synonym: "Tryptamine" EXACT [KEGG_COMPOUND]
xref: Beilstein:125513 {source="Beilstein"}
xref: CAS:61-54-1 {source="ChemIDplus"}
xref: CAS:61-54-1 {source="NIST Chemistry WebBook"}
xref: CAS:61-54-1 {source="KEGG COMPOUND"}
xref: DrugBank:DB08653
xref: Gmelin:603448 {source="Gmelin"}
xref: HMDB:HMDB0000303
xref: KEGG:C00398
xref: KNApSAcK:C00001434
xref: MetaCyc:TRYPTAMINE
xref: PDBeChem:TSS
xref: PMID:16126914 {source="Europe PMC"}
xref: PMID:22770225 {source="Europe PMC"}
xref: PMID:24345948 {source="Europe PMC"}
xref: PMID:24558969 {source="Europe PMC"}
xref: Reaxys:125513 {source="Reaxys"}
xref: Wikipedia:Tryptamine
is_a: CHEBI:27162 ! tryptamines
is_a: CHEBI:38631 ! aminoalkylindole
is_a: CHEBI:38958 ! indole alkaloid
is_a: CHEBI:64365 ! aralkylamino compound
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: has_role CHEBI:76924 ! plant metabolite
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_base_of CHEBI:57887 ! tryptaminium
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H12N2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "APJYDQYYACXCRM-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "160.21570" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "160.10005" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCCc1c[nH]c2ccccc12" xsd:string

[Term]
id: CHEBI:16990
name: bilirubin IXalpha
namespace: chebi_ontology
alt_id: CHEBI:13898
alt_id: CHEBI:22870
alt_id: CHEBI:3099
def: "A member of the class of  biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin." []
subset: 3_STAR
synonym: "1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid" RELATED [ChemIDplus]
synonym: "2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid" RELATED [ChemIDplus]
synonym: "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" RELATED [IUPAC]
synonym: "3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" EXACT IUPAC_NAME [IUPAC]
synonym: "8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione" RELATED [JCBN]
synonym: "Bilirubin" RELATED [KEGG_COMPOUND]
synonym: "bilirubin" EXACT IUPAC_NAME [IUPAC]
synonym: "bilirubin(Z,Z)" RELATED [ChEBI]
synonym: "bilirubin-IXalpha" RELATED [ChEBI]
xref: Beilstein:74376 {source="Beilstein"}
xref: CAS:635-65-4 {source="KEGG COMPOUND"}
xref: CAS:635-65-4 {source="ChemIDplus"}
xref: Gmelin:411033 {source="Gmelin"}
xref: HMDB:HMDB0000054
xref: KEGG:C00486
xref: KNApSAcK:C00029828
xref: MetaCyc:BILIRUBIN
xref: PDBeChem:BLR
xref: PMID:12799017 {source="Europe PMC"}
xref: PMID:18442622 {source="Europe PMC"}
xref: PMID:23763371 {source="Europe PMC"}
xref: PMID:23768684 {source="Europe PMC"}
xref: PMID:30224965 {source="Europe PMC"}
xref: PMID:8605219 {source="Europe PMC"}
xref: PMID:9587403 {source="Europe PMC"}
xref: Reaxys:74376 {source="Reaxys"}
xref: Wikipedia:Bilirubin
is_a: CHEBI:35692 ! dicarboxylic acid
is_a: CHEBI:36735 ! biladienes
relationship: has_part CHEBI:142163 ! 24G7 epitope
relationship: has_role CHEBI:22586 ! antioxidant
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_acid_of CHEBI:57977 ! bilirubin(2-)
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C33H36N4O6" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BPYKTIZUTYGOLE-IFADSCNNSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "584.673" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "584.26348" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC1=C(C=C)\\C(NC1=O)=C\\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\\C=C2/NC(=O)C(C=C)=C2C)N1" xsd:string

[Term]
id: CHEBI:16991
name: deoxyribonucleic acid
namespace: chebi_ontology
alt_id: CHEBI:13302
alt_id: CHEBI:21123
alt_id: CHEBI:33698
alt_id: CHEBI:4291
def: "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." []
subset: 3_STAR
synonym: "(Deoxyribonucleotide)m" RELATED [KEGG_COMPOUND]
synonym: "(Deoxyribonucleotide)n" RELATED [KEGG_COMPOUND]
synonym: "(Deoxyribonucleotide)n+m" RELATED [KEGG_COMPOUND]
synonym: "Deoxyribonucleic acid" EXACT [KEGG_COMPOUND]
synonym: "deoxyribonucleic acids" EXACT IUPAC_NAME [IUPAC]
synonym: "deoxyribonucleic acids" RELATED [ChEBI]
synonym: "Desoxyribonukleinsaeure" RELATED [ChEBI]
synonym: "desoxyribose nucleic acid" RELATED [ChemIDplus]
synonym: "DNA" RELATED [UniProt]
synonym: "DNA" RELATED [KEGG_COMPOUND]
synonym: "DNA" RELATED [IUPAC]
synonym: "DNAn" RELATED [KEGG_COMPOUND]
synonym: "DNAn+1" RELATED [KEGG_COMPOUND]
synonym: "DNS" RELATED [ChEBI]
synonym: "thymus nucleic acid" RELATED [ChEBI]
xref: CAS:9007-49-2 {source="ChemIDplus"}
xref: CAS:9007-49-2 {source="KEGG COMPOUND"}
xref: KEGG:C00039
is_a: CHEBI:33696 ! nucleic acid
relationship: has_part CHEBI:33793 ! canonical deoxyribonucleoside residue
relationship: has_part CHEBI:50298 ! canonical deoxyribonucleotide residue
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: has_role CHEBI:77746 ! human metabolite

[Term]
id: CHEBI:17029
name: chitin
namespace: chebi_ontology
alt_id: CHEBI:13962
alt_id: CHEBI:23099
alt_id: CHEBI:3596
def: "An aminoglycan consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." []
subset: 3_STAR
synonym: "(1->4)-2-acetamido-2-deoxy-beta-D-glucan" EXACT IUPAC_NAME [IUPAC]
synonym: "[1,4-(N-Acetyl-beta-D-glucosaminyl)]n" RELATED [KEGG_COMPOUND]
synonym: "[4)-beta-D-GlcpNAc(1->]n" RELATED [IUPAC]
synonym: "beta-1,4-Poly-N-acetyl-D-glucosamine" RELATED [KEGG_COMPOUND]
synonym: "Chitin" EXACT [KEGG_COMPOUND]
synonym: "chitin" EXACT [IUPAC]
synonym: "chitin" EXACT [UniProt]
xref: CAS:1398-61-4 {source="KEGG COMPOUND"}
xref: KEGG:C00461
xref: KEGG:G10483
is_a: CHEBI:21638 ! N-acylglucosamine
is_a: CHEBI:22506 ! aminoglycan
relationship: has_role CHEBI:73336 ! vulnerary
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite
relationship: has_role CHEBI:77746 ! human metabolite
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O(C8H13NO5)n" xsd:string

[Term]
id: CHEBI:17087
name: ketone
namespace: chebi_ontology
alt_id: CHEBI:13427
alt_id: CHEBI:13646
alt_id: CHEBI:24974
alt_id: CHEBI:6127
alt_id: CHEBI:8742
def: "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." []
subset: 3_STAR
synonym: "a ketone" RELATED [UniProt]
synonym: "cetone" RELATED [ChEBI]
synonym: "Keton" RELATED [ChEBI]
synonym: "Ketone" EXACT [KEGG_COMPOUND]
synonym: "ketones" EXACT IUPAC_NAME [IUPAC]
synonym: "ketones" RELATED [ChEBI]
synonym: "R-CO-R'" RELATED [KEGG_COMPOUND]
xref: KEGG:C01450
xref: Wikipedia:Ketone
is_a: CHEBI:36586 ! carbonyl compound
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "COR2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "28.010" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "27.99491" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C([*])=O" xsd:string

[Term]
id: CHEBI:17089
name: glycoprotein
namespace: chebi_ontology
alt_id: CHEBI:14349
alt_id: CHEBI:5481
alt_id: CHEBI:5493
def: "A compound in which a carbohydrate component is covalently bound to a protein component." []
subset: 3_STAR
synonym: "a glycoprotein" RELATED [UniProt]
synonym: "glicoproteina" RELATED [ChEBI]
synonym: "glicoproteinas" RELATED [ChEBI]
synonym: "Glycoprotein" EXACT [KEGG_COMPOUND]
synonym: "glycoproteine" RELATED [ChEBI]
synonym: "glycoproteines" RELATED [ChEBI]
synonym: "glycoproteins" EXACT IUPAC_NAME [IUPAC]
synonym: "Glykoprotein" RELATED [ChEBI]
synonym: "Glykoproteine" RELATED [ChEBI]
xref: KEGG:C00326
is_a: CHEBI:33837 ! conjugated protein
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:17234
name: glucose
namespace: chebi_ontology
alt_id: CHEBI:14313
alt_id: CHEBI:24277
alt_id: CHEBI:33929
alt_id: CHEBI:5418
def: "An aldohexose used as a source of energy and metabolic intermediate." []
subset: 3_STAR
synonym: "DL-glucose" RELATED [ChEBI]
synonym: "Glc" RELATED [JCBN]
synonym: "gluco-hexose" EXACT IUPAC_NAME [IUPAC]
synonym: "Glucose" EXACT [KEGG_COMPOUND]
synonym: "glucose" EXACT IUPAC_NAME [IUPAC]
synonym: "Glukose" RELATED [ChEBI]
xref: CAS:50-99-7 {source="KEGG COMPOUND"}
xref: KEGG:C00293
xref: Wikipedia:Glucose
is_a: CHEBI:33917 ! aldohexose
relationship: has_role CHEBI:78675 ! fundamental metabolite
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H12O6" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "180.15588" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "180.06339" xsd:string

[Term]
id: CHEBI:17544
name: hydrogencarbonate
namespace: chebi_ontology
alt_id: CHEBI:13363
alt_id: CHEBI:22863
alt_id: CHEBI:40961
alt_id: CHEBI:5589
def: "The carbon oxoanion resulting from the removal of a proton from carbonic acid." []
subset: 3_STAR
synonym: "[CO2(OH)](-)" RELATED [IUPAC]
synonym: "Acid carbonate" RELATED [KEGG_COMPOUND]
synonym: "Bicarbonate" RELATED [KEGG_COMPOUND]
synonym: "BICARBONATE ION" RELATED [PDBeChem]
synonym: "HCO3(-)" RELATED [IUPAC]
synonym: "HCO3-" RELATED [KEGG_COMPOUND]
synonym: "hydrogen carbonate" RELATED [PDBeChem]
synonym: "hydrogen(trioxidocarbonate)(1-)" EXACT IUPAC_NAME [IUPAC]
synonym: "Hydrogencarbonate" EXACT [KEGG_COMPOUND]
synonym: "hydrogencarbonate" EXACT [UniProt]
synonym: "hydrogencarbonate" EXACT IUPAC_NAME [IUPAC]
synonym: "hydrogencarbonate(1-)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydrogentrioxocarbonate(1-)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydrogentrioxocarbonate(IV)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydroxidodioxidocarbonate(1-)" EXACT IUPAC_NAME [IUPAC]
xref: Beilstein:3903504 {source="Beilstein"}
xref: CAS:71-52-3 {source="ChemIDplus"}
xref: Gmelin:49249 {source="Gmelin"}
xref: HMDB:HMDB0000595
xref: KEGG:C00288
xref: MetaCyc:HCO3
xref: PDBeChem:BCT
xref: PMID:17215880 {source="Europe PMC"}
xref: PMID:17505962 {source="Europe PMC"}
xref: PMID:18439416 {source="Europe PMC"}
xref: PMID:28732801 {source="Europe PMC"}
xref: PMID:29150416 {source="Europe PMC"}
xref: PMID:29460248 {source="Europe PMC"}
xref: PMID:29466234 {source="Europe PMC"}
xref: PMID:4208463 {source="Europe PMC"}
xref: Wikipedia:Bicarbonate
is_a: CHEBI:35604 ! carbon oxoanion
relationship: has_role CHEBI:23357 ! cofactor
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite
relationship: has_role CHEBI:76971 ! Escherichia coli metabolite
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_acid_of CHEBI:41609 ! carbonate
relationship: is_conjugate_base_of CHEBI:28976 ! carbonic acid
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-M" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "61.01684" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.99312" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([O-])=O" xsd:string

[Term]
id: CHEBI:17891
name: donor
namespace: chebi_ontology
alt_id: CHEBI:14202
alt_id: CHEBI:4697
def: "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." []
subset: 3_STAR
synonym: "Donator" RELATED [ChEBI]
synonym: "donneur" RELATED [ChEBI]
synonym: "Donor" EXACT [KEGG_COMPOUND]
xref: KEGG:C01351
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:18059
name: lipid
namespace: chebi_ontology
alt_id: CHEBI:14517
alt_id: CHEBI:25054
alt_id: CHEBI:6486
def: "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." []
subset: 3_STAR
synonym: "Lipid" EXACT [KEGG_COMPOUND]
synonym: "lipids" EXACT IUPAC_NAME [IUPAC]
xref: KEGG:C01356
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:18085
name: glycosaminoglycan
namespace: chebi_ontology
alt_id: CHEBI:14361
alt_id: CHEBI:24398
alt_id: CHEBI:5495
def: "Any polysaccharide containing a substantial proportion of aminomonosaccharide residues." []
subset: 3_STAR
synonym: "glicosaminoglicano" RELATED [IUPAC]
synonym: "Glycosaminoglycan" EXACT [KEGG_COMPOUND]
synonym: "glycosaminoglycan" EXACT IUPAC_NAME [IUPAC]
synonym: "glycosaminoglycane" RELATED [IUPAC]
synonym: "glycosaminoglycans" RELATED [ChEBI]
synonym: "Glykosaminoglykan" RELATED [ChEBI]
xref: KEGG:C02545
xref: Wikipedia:Glycosaminoglycan
is_a: CHEBI:22506 ! aminoglycan

[Term]
id: CHEBI:18133
name: hexose
namespace: chebi_ontology
alt_id: CHEBI:14399
alt_id: CHEBI:24590
alt_id: CHEBI:5709
def: "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." []
subset: 3_STAR
synonym: "Hexose" EXACT [KEGG_COMPOUND]
synonym: "hexoses" RELATED [ChEBI]
synonym: "WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/" RELATED [GlyTouCan]
xref: GlyGen:G70994MS
xref: GlyTouCan:G70994MS
xref: KEGG:C00738
is_a: CHEBI:35381 ! monosaccharide

[Term]
id: CHEBI:18154
name: polysaccharide
namespace: chebi_ontology
alt_id: CHEBI:14864
alt_id: CHEBI:26205
alt_id: CHEBI:8322
def: "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." []
subset: 3_STAR
synonym: "Glycan" RELATED [KEGG_COMPOUND]
synonym: "Glycane" RELATED [ChEBI]
synonym: "glycans" RELATED [IUPAC]
synonym: "Glykan" RELATED [ChEBI]
synonym: "Glykane" RELATED [ChEBI]
synonym: "polisacarido" RELATED [ChEBI]
synonym: "polisacaridos" RELATED [IUPAC]
synonym: "Polysaccharide" EXACT [KEGG_COMPOUND]
synonym: "polysaccharides" EXACT IUPAC_NAME [IUPAC]
xref: KEGG:C00420
is_a: CHEBI:16646 ! carbohydrate
is_a: CHEBI:167559 ! glycan
is_a: CHEBI:33694 ! biomacromolecule

[Term]
id: CHEBI:18282
name: nucleobase
namespace: chebi_ontology
alt_id: CHEBI:13873
alt_id: CHEBI:25598
alt_id: CHEBI:2995
def: "That part of DNA or RNA that may be involved in pairing." []
subset: 3_STAR
synonym: "Base" RELATED [KEGG_COMPOUND]
synonym: "nucleobases" RELATED [ChEBI]
xref: KEGG:C00701
xref: Wikipedia:Nucleobase
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:18357
name: (R)-noradrenaline
namespace: chebi_ontology
alt_id: CHEBI:1
alt_id: CHEBI:14668
alt_id: CHEBI:25592
alt_id: CHEBI:258884
alt_id: CHEBI:43725
def: "The R-enantiomer of noradrenaline." []
subset: 3_STAR
synonym: "(-)-arterenol" RELATED [ChemIDplus]
synonym: "(-)-noradrenaline" RELATED [IUPHAR]
synonym: "(-)-norepinephrine" RELATED [ChemIDplus]
synonym: "(R)-(-)-norepinephrine" RELATED [ChemIDplus]
synonym: "(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol" RELATED [ChemIDplus]
synonym: "(R)-norepinephrine" RELATED [ChemIDplus]
synonym: "4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol" RELATED [KEGG_COMPOUND]
synonym: "4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC]
synonym: "Arterenol" RELATED [KEGG_COMPOUND]
synonym: "L-Noradrenaline" RELATED [KEGG_COMPOUND]
synonym: "L-NOREPINEPHRINE" RELATED [PDBeChem]
synonym: "Noradrenaline" RELATED [KEGG_COMPOUND]
synonym: "norepinefrina" RELATED INN [ChEBI]
synonym: "Norepinephrine" RELATED [KEGG_COMPOUND]
synonym: "norepinephrine" RELATED INN [ChemIDplus]
synonym: "norepinephrine" RELATED INN [WHO_MedNet]
synonym: "norepinephrinum" RELATED INN [ChEBI]
xref: Beilstein:2804840 {source="Beilstein"}
xref: Beilstein:4231961 {source="ChemIDplus"}
xref: CAS:51-41-2 {source="ChemIDplus"}
xref: CAS:51-41-2 {source="KEGG COMPOUND"}
xref: Drug_Central:1960 {source="DrugCentral"}
xref: DrugBank:DB00368
xref: HMDB:HMDB0000216
xref: KEGG:C00547
xref: KEGG:D00076
xref: KNApSAcK:C00001424
xref: PDBeChem:LNR
xref: Reaxys:2804840 {source="Reaxys"}
xref: Wikipedia:Norepinephrine
is_a: CHEBI:33569 ! noradrenaline
relationship: has_role CHEBI:25512 ! neurotransmitter
relationship: has_role CHEBI:35524 ! sympathomimetic agent
relationship: has_role CHEBI:35569 ! alpha-adrenergic agonist
relationship: has_role CHEBI:50514 ! vasoconstrictor agent
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: is_conjugate_base_of CHEBI:72587 ! (R)-noradrenaline(1+)
relationship: is_enantiomer_of CHEBI:33571 ! (S)-noradrenaline
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-QMMMGPOBSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17780" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC[C@H](O)c1ccc(O)c(O)c1" xsd:string

[Term]
id: CHEBI:18367
name: phosphate(3-)
namespace: chebi_ontology
alt_id: CHEBI:14791
alt_id: CHEBI:45024
alt_id: CHEBI:7793
def: "A phosphate ion that is the conjugate base of hydrogenphosphate." []
subset: 3_STAR
synonym: "[PO4](3-)" RELATED [IUPAC]
synonym: "Orthophosphate" RELATED [KEGG_COMPOUND]
synonym: "Phosphate" RELATED [KEGG_COMPOUND]
synonym: "phosphate" EXACT IUPAC_NAME [IUPAC]
synonym: "PHOSPHATE ION" RELATED [PDBeChem]
synonym: "PO4(3-)" RELATED [IUPAC]
synonym: "tetraoxidophosphate(3-)" EXACT IUPAC_NAME [IUPAC]
synonym: "tetraoxophosphate(3-)" EXACT IUPAC_NAME [IUPAC]
synonym: "tetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC]
xref: Beilstein:3903772 {source="Beilstein"}
xref: CAS:14265-44-2 {source="KEGG COMPOUND"}
xref: CAS:14265-44-2 {source="ChemIDplus"}
xref: Gmelin:1997 {source="Gmelin"}
xref: KEGG:C00009
xref: PDBeChem:PO4 {source="ChEBI"}
xref: Reaxys:3903772 {source="Reaxys"}
is_a: CHEBI:35780 ! phosphate ion
is_a: CHEBI:79387 ! trivalent inorganic anion
relationship: is_conjugate_base_of CHEBI:43474 ! hydrogenphosphate
property_value: http://purl.obolibrary.org/obo/chebi/charge "-3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "O4P" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-K" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "94.97136" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "94.95507" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]P([O-])([O-])=O" xsd:string

[Term]
id: CHEBI:20664
name: 5beta-cholane
namespace: chebi_ontology
subset: 3_STAR
synonym: "5beta-cholane" EXACT IUPAC_NAME [IUPAC]
xref: Beilstein:2048472 {source="Beilstein"}
is_a: CHEBI:35519 ! cholane
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H42" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18+,19+,20-,21+,22+,23+,24-/m1/s1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QSHQKIURKJITMZ-OBUPQJQESA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "330.59028" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "330.32865" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC" xsd:string

[Term]
id: CHEBI:21638
name: N-acylglucosamine
namespace: chebi_ontology
subset: 3_STAR
synonym: "N-acylglucosamine" EXACT [ChEBI]
synonym: "N-acylglucosamines" RELATED [ChEBI]
is_a: CHEBI:21656 ! N-acyl-hexosamine
is_a: CHEBI:24271 ! glucosamines

[Term]
id: CHEBI:21656
name: N-acyl-hexosamine
namespace: chebi_ontology
subset: 3_STAR
synonym: "N-acyl-hexosamine" EXACT [ChEBI]
synonym: "N-acyl-hexosamines" RELATED [ChEBI]
is_a: CHEBI:24586 ! hexosamine

[Term]
id: CHEBI:22221
name: acyl group
namespace: chebi_ontology
def: "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." []
subset: 3_STAR
synonym: "acyl group" EXACT [IUPAC]
synonym: "acyl groups" RELATED [ChEBI]
synonym: "alkanoyl" EXACT IUPAC_NAME [IUPAC]
synonym: "alkanoyl group" RELATED [ChEBI]
synonym: "groupe acyle" RELATED [IUPAC]
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:22314
name: alkali metal atom
namespace: chebi_ontology
subset: 3_STAR
synonym: "alkali metal" RELATED [ChEBI]
synonym: "alkali metals" EXACT IUPAC_NAME [IUPAC]
synonym: "Alkalimetall" RELATED [ChEBI]
synonym: "Alkalimetalle" RELATED [ChEBI]
synonym: "metal alcalin" RELATED [ChEBI]
synonym: "metal alcalino" RELATED [ChEBI]
synonym: "metales alcalinos" RELATED [ChEBI]
synonym: "metaux alcalins" RELATED [ChEBI]
is_a: CHEBI:33318 ! main group element atom
is_a: CHEBI:33521 ! metal atom
is_a: CHEBI:33559 ! s-block element atom

[Term]
id: CHEBI:22315
name: alkaloid
namespace: chebi_ontology
def: "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is  exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." []
subset: 3_STAR
synonym: "alcaloide" RELATED [ChEBI]
synonym: "alcaloides" RELATED [ChEBI]
synonym: "Alkaloid" EXACT [ChEBI]
synonym: "Alkaloide" RELATED [ChEBI]
synonym: "alkaloids" EXACT IUPAC_NAME [IUPAC]
xref: Wikipedia:Alkaloid
is_a: CHEBI:35352 ! organonitrogen compound
relationship: has_role CHEBI:25212 ! metabolite

[Term]
id: CHEBI:22506
name: aminoglycan
namespace: chebi_ontology
subset: 3_STAR
synonym: "aminoglycans" RELATED [ChEBI]
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:65212 ! polysaccharide derivative

[Term]
id: CHEBI:22563
name: anion
namespace: chebi_ontology
def: "A monoatomic or polyatomic species having one or more elementary charges of the electron." []
subset: 3_STAR
synonym: "Anion" EXACT [ChEBI]
synonym: "anion" EXACT IUPAC_NAME [IUPAC]
synonym: "anion" EXACT [ChEBI]
synonym: "Anionen" RELATED [ChEBI]
synonym: "aniones" RELATED [ChEBI]
synonym: "anions" RELATED [IUPAC]
is_a: CHEBI:24870 ! ion

[Term]
id: CHEBI:22586
name: antioxidant
namespace: chebi_ontology
def: "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." []
subset: 3_STAR
synonym: "antioxidants" RELATED [ChEBI]
synonym: "antioxydant" RELATED [ChEBI]
synonym: "antoxidant" RELATED [ChEBI]
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:22695
name: base
namespace: chebi_ontology
def: "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." []
subset: 3_STAR
synonym: "Base" EXACT [ChEBI]
synonym: "base" EXACT [ChEBI]
synonym: "base" EXACT IUPAC_NAME [IUPAC]
synonym: "Base1" RELATED [KEGG_COMPOUND]
synonym: "Base2" RELATED [KEGG_COMPOUND]
synonym: "Basen" RELATED [ChEBI]
synonym: "bases" RELATED [ChEBI]
synonym: "Nucleobase" RELATED [KEGG_COMPOUND]
xref: KEGG:C00701
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:22728
name: benzopyrrole
namespace: chebi_ontology
subset: 3_STAR
synonym: "benzopyrroles" RELATED [ChEBI]
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38180 ! polycyclic heteroarene

[Term]
id: CHEBI:22868
name: bile salt
namespace: chebi_ontology
def: "A sodium salt of the conjugate of any bile acid with either glycine or taurine." []
subset: 3_STAR
synonym: "Bile acid" RELATED [KEGG_COMPOUND]
synonym: "bile salts" RELATED [ChEBI]
xref: KEGG:C01558
is_a: CHEBI:36078 ! cholanoid
is_a: CHEBI:38700 ! organic sodium salt

[Term]
id: CHEBI:23004
name: carbamoyl group
namespace: chebi_ontology
def: "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." []
subset: 3_STAR
synonym: "-C(O)NH2" RELATED [ChEBI]
synonym: "-CONH2" RELATED [IUPAC]
synonym: "aminocarbonyl" RELATED [IUPAC]
synonym: "carbamoyl" EXACT IUPAC_NAME [IUPAC]
synonym: "carbamyl" RELATED [ChEBI]
synonym: "carbamyl group" RELATED [ChEBI]
synonym: "carboxamide" RELATED [IUPAC]
xref: PMID:24168430 {source="Europe PMC"}
is_a: CHEBI:27207 ! univalent carboacyl group
relationship: is_substituent_group_from CHEBI:28616 ! carbamic acid
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2NO" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "44.03272" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.01364" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(N)=O" xsd:string

[Term]
id: CHEBI:23019
name: carbonyl group
namespace: chebi_ontology
subset: 3_STAR
synonym: ">C=O" RELATED [IUPAC]
synonym: "carbonyl" EXACT IUPAC_NAME [IUPAC]
synonym: "carbonyl group" EXACT [ChEBI]
synonym: "carbonyl group" EXACT [UniProt]
is_a: CHEBI:51422 ! organodiyl group
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CO" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "28.01010" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "27.99491" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=C(*)*" xsd:string

[Term]
id: CHEBI:23357
name: cofactor
namespace: chebi_ontology
def: "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." []
subset: 3_STAR
synonym: "cofactor" EXACT [IUPAC]
synonym: "cofactors" EXACT IUPAC_NAME [IUPAC]
xref: Wikipedia:Cofactor_(biochemistry)
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:23367
name: molecular entity
namespace: chebi_ontology
def: "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." [fake:2]
subset: 3_STAR
synonym: "entidad molecular" RELATED [IUPAC]
synonym: "entidades moleculares" RELATED [IUPAC]
synonym: "entite moleculaire" RELATED [IUPAC]
synonym: "molecular entities" RELATED [IUPAC]
synonym: "molecular entity" EXACT IUPAC_NAME [IUPAC]
synonym: "molekulare Entitaet" RELATED [ChEBI]
is_a: CHEBI:24431 ! chemical entity

[Term]
id: CHEBI:23449
name: cyclic peptide
namespace: chebi_ontology
subset: 3_STAR
synonym: "cyclic peptides" RELATED [ChEBI]
synonym: "Cyclopeptid" RELATED [ChEBI]
synonym: "peptide cyclique" RELATED [IUPAC]
synonym: "peptido ciclico" RELATED [IUPAC]
synonym: "Zyklopeptid" RELATED [ChEBI]
is_a: CHEBI:16670 ! peptide

[Term]
id: CHEBI:23888
name: drug
namespace: chebi_ontology
def: "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." []
subset: 3_STAR
synonym: "drugs" RELATED [ChEBI]
synonym: "medicine" RELATED [ChEBI]
is_a: CHEBI:52217 ! pharmaceutical

[Term]
id: CHEBI:23906
name: monoatomic cation
namespace: chebi_ontology
subset: 3_STAR
synonym: "monoatomic cations" RELATED [ChEBI]
is_a: CHEBI:24867 ! monoatomic ion
is_a: CHEBI:36916 ! cation

[Term]
id: CHEBI:23924
name: enzyme inhibitor
namespace: chebi_ontology
def: "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." []
subset: 3_STAR
synonym: "enzyme inhibitor" EXACT IUPAC_NAME [IUPAC]
synonym: "enzyme inhibitors" RELATED [ChEBI]
synonym: "inhibidor enzimatico" RELATED [ChEBI]
synonym: "inhibidores enzimaticos" RELATED [ChEBI]
synonym: "inhibiteur enzymatique" RELATED [ChEBI]
synonym: "inhibiteurs enzymatiques" RELATED [ChEBI]
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:24271
name: glucosamines
namespace: chebi_ontology
def: "Any  hexosamine that is glucose in which at least one of the hydroxy groups has been replaced by an amino group." []
subset: 3_STAR
is_a: CHEBI:24586 ! hexosamine

[Term]
id: CHEBI:24384
name: glycogens
namespace: chebi_ontology
subset: 3_STAR
is_a: CHEBI:37163 ! glucan

[Term]
id: CHEBI:24431
name: chemical entity
namespace: chebi_ontology
def: "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." []
subset: 3_STAR
synonym: "chemical entity" EXACT [UniProt]
is_a: BFO:0000030 ! object

[Term]
id: CHEBI:24432
name: biological role
namespace: chebi_ontology
def: "A role played by the molecular entity or part thereof within a biological context." []
subset: 3_STAR
synonym: "biological function" RELATED [ChEBI]
is_a: CHEBI:50906 ! role

[Term]
id: CHEBI:24433
name: group
namespace: chebi_ontology
def: "A defined linked collection of atoms or a single atom within a molecular entity." []
subset: 3_STAR
synonym: "group" EXACT IUPAC_NAME [IUPAC]
synonym: "groupe" RELATED [IUPAC]
synonym: "grupo" RELATED [IUPAC]
synonym: "grupos" RELATED [IUPAC]
synonym: "Gruppe" RELATED [ChEBI]
synonym: "Rest" RELATED [ChEBI]
is_a: CHEBI:24431 ! chemical entity
relationship: has_part CHEBI:33250 ! atom

[Term]
id: CHEBI:24532
name: organic heterocyclic compound
namespace: chebi_ontology
def: "A cyclic compound having as ring members atoms of carbon and at least of one other element." []
subset: 3_STAR
synonym: "organic heterocycle" RELATED [ChEBI]
synonym: "organic heterocyclic compounds" RELATED [ChEBI]
is_a: CHEBI:33285 ! heteroorganic entity
is_a: CHEBI:33832 ! organic cyclic compound
is_a: CHEBI:5686 ! heterocyclic compound

[Term]
id: CHEBI:24533
name: heterodetic cyclic peptide
namespace: chebi_ontology
def: "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." []
subset: 3_STAR
synonym: "heterodetic cyclic peptide" EXACT IUPAC_NAME [IUPAC]
synonym: "heterodetic cyclic peptides" RELATED [ChEBI]
synonym: "peptide cyclique heterodetique" RELATED [IUPAC]
synonym: "peptido ciclico heterodetico" RELATED [IUPAC]
is_a: CHEBI:23449 ! cyclic peptide

[Term]
id: CHEBI:24586
name: hexosamine
namespace: chebi_ontology
def: "Any 6-carbon amino monosaccharide with at least one alcoholic hydroxy group replaced by an amino group." []
subset: 3_STAR
synonym: "hexosamine" EXACT [ChEBI]
synonym: "hexosamines" RELATED [ChEBI]
is_a: CHEBI:60926 ! amino monosaccharide

[Term]
id: CHEBI:24621
name: hormone
namespace: chebi_ontology
def: "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." []
subset: 3_STAR
synonym: "endocrine" RELATED [ChEBI]
synonym: "hormones" RELATED [ChEBI]
is_a: CHEBI:33280 ! molecular messenger
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:24651
name: hydroxides
namespace: chebi_ontology
def: "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." []
subset: 3_STAR
is_a: CHEBI:25806 ! oxygen molecular entity
is_a: CHEBI:33608 ! hydrogen molecular entity
is_a: CHEBI:37577 ! heteroatomic molecular entity
relationship: has_part CHEBI:43176 ! hydroxy group

[Term]
id: CHEBI:24663
name: hydroxy-5beta-cholanic acid
namespace: chebi_ontology
def: "Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position." []
subset: 3_STAR
synonym: "hydroxy-5beta-cholanic acids" RELATED [ChEBI]
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:36248 ! 5beta-cholanic acids
relationship: has_functional_parent CHEBI:36238 ! 5beta-cholanic acid

[Term]
id: CHEBI:24828
name: indoles
namespace: chebi_ontology
def: "Any compound containing an indole skeleton." []
subset: 3_STAR
is_a: CHEBI:22728 ! benzopyrrole

[Term]
id: CHEBI:24833
name: oxoacid
namespace: chebi_ontology
def: "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." []
subset: 3_STAR
synonym: "oxacids" RELATED [ChEBI]
synonym: "oxiacids" RELATED [ChEBI]
synonym: "oxo acid" RELATED [ChEBI]
synonym: "oxoacid" EXACT IUPAC_NAME [IUPAC]
synonym: "oxoacids" EXACT IUPAC_NAME [IUPAC]
synonym: "oxy-acids" RELATED [ChEBI]
synonym: "oxyacids" RELATED [ChEBI]
is_a: CHEBI:24651 ! hydroxides
relationship: has_role CHEBI:39141 ! Bronsted acid

[Term]
id: CHEBI:24834
name: inorganic anion
namespace: chebi_ontology
subset: 3_STAR
synonym: "inorganic anions" RELATED [ChEBI]
is_a: CHEBI:22563 ! anion
is_a: CHEBI:36914 ! inorganic ion

[Term]
id: CHEBI:24835
name: inorganic molecular entity
namespace: chebi_ontology
def: "A molecular entity that contains no carbon." []
subset: 3_STAR
synonym: "anorganische Verbindungen" RELATED [ChEBI]
synonym: "inorganic compounds" RELATED [ChEBI]
synonym: "inorganic entity" RELATED [ChEBI]
synonym: "inorganic molecular entities" RELATED [ChEBI]
synonym: "inorganics" RELATED [ChEBI]
is_a: CHEBI:23367 ! molecular entity

[Term]
id: CHEBI:24836
name: inorganic oxide
namespace: chebi_ontology
subset: 3_STAR
synonym: "inorganic oxides" RELATED [ChEBI]
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:25741 ! oxide

[Term]
id: CHEBI:24866
name: salt
namespace: chebi_ontology
def: "A salt is an assembly of cations and anions." []
subset: 3_STAR
synonym: "ionic compound" RELATED [ChEBI]
synonym: "ionic compounds" RELATED [ChEBI]
synonym: "sal" RELATED [ChEBI]
synonym: "sales" RELATED [ChEBI]
synonym: "salt" EXACT IUPAC_NAME [IUPAC]
synonym: "salts" RELATED [ChEBI]
synonym: "Salz" RELATED [ChEBI]
synonym: "Salze" RELATED [ChEBI]
synonym: "sel" RELATED [ChEBI]
synonym: "sels" RELATED [ChEBI]
is_a: CHEBI:37577 ! heteroatomic molecular entity
relationship: has_part CHEBI:22563 ! anion
relationship: has_part CHEBI:36916 ! cation

[Term]
id: CHEBI:24867
name: monoatomic ion
namespace: chebi_ontology
subset: 3_STAR
synonym: "monoatomic ions" RELATED [ChEBI]
is_a: CHEBI:24870 ! ion
is_a: CHEBI:33238 ! monoatomic entity

[Term]
id: CHEBI:24868
name: organic salt
namespace: chebi_ontology
subset: 3_STAR
synonym: "organic salts" RELATED [ChEBI]
synonym: "organisches Salz" RELATED [ChEBI]
is_a: CHEBI:24866 ! salt

[Term]
id: CHEBI:24870
name: ion
namespace: chebi_ontology
def: "A molecular entity having a net electric charge." []
subset: 3_STAR
synonym: "Ion" EXACT [ChEBI]
synonym: "ion" EXACT IUPAC_NAME [IUPAC]
synonym: "ion" EXACT [ChEBI]
synonym: "Ionen" RELATED [ChEBI]
synonym: "iones" RELATED [ChEBI]
synonym: "ions" RELATED [ChEBI]
is_a: CHEBI:23367 ! molecular entity

[Term]
id: CHEBI:25046
name: linear tetrapyrrole
namespace: chebi_ontology
subset: 1_STAR
is_a: CHEBI:26932 ! tetrapyrrole

[Term]
id: CHEBI:25212
name: metabolite
namespace: chebi_ontology
alt_id: CHEBI:26619
alt_id: CHEBI:35220
def: "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." []
subset: 3_STAR
synonym: "metabolite" EXACT IUPAC_NAME [IUPAC]
synonym: "metabolites" RELATED [ChEBI]
synonym: "primary metabolites" RELATED [ChEBI]
synonym: "secondary metabolites" RELATED [ChEBI]
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:25213
name: metal cation
namespace: chebi_ontology
subset: 3_STAR
synonym: "a metal cation" RELATED [UniProt]
synonym: "metal cations" RELATED [ChEBI]
is_a: CHEBI:23906 ! monoatomic cation
is_a: CHEBI:36915 ! inorganic cation

[Term]
id: CHEBI:25362
name: elemental molecule
namespace: chebi_ontology
def: "A molecule all atoms of which have the same atomic number." []
subset: 3_STAR
synonym: "homoatomic molecule" RELATED [ChEBI]
synonym: "homoatomic molecules" RELATED [ChEBI]
is_a: CHEBI:25367 ! molecule
is_a: CHEBI:33259 ! elemental molecular entity

[Term]
id: CHEBI:25367
name: molecule
namespace: chebi_ontology
def: "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." []
subset: 3_STAR
synonym: "molecula" RELATED [IUPAC]
synonym: "molecule" EXACT [IUPAC]
synonym: "molecules" RELATED [IUPAC]
synonym: "Molekuel" RELATED [ChEBI]
synonym: "neutral molecular compounds" RELATED [IUPAC]
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:25375
name: monoamine molecular messenger
namespace: chebi_ontology
def: "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group  (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." []
subset: 3_STAR
synonym: "monamines" RELATED [ChEBI]
synonym: "monoamines" RELATED [ChEBI]
is_a: CHEBI:63534 ! monoamine
relationship: has_role CHEBI:33280 ! molecular messenger

[Term]
id: CHEBI:25384
name: monocarboxylic acid
namespace: chebi_ontology
def: "An oxoacid containing a single carboxy group." []
subset: 3_STAR
synonym: "monocarboxylic acids" RELATED [ChEBI]
is_a: CHEBI:33575 ! carboxylic acid
relationship: is_conjugate_acid_of CHEBI:35757 ! monocarboxylic acid anion

[Term]
id: CHEBI:25414
name: monoatomic monocation
namespace: chebi_ontology
subset: 3_STAR
synonym: "monoatomic monocations" RELATED [ChEBI]
synonym: "monovalent inorganic cations" RELATED [ChEBI]
is_a: CHEBI:23906 ! monoatomic cation
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "0.00000" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*+]" xsd:string

[Term]
id: CHEBI:25512
name: neurotransmitter
namespace: chebi_ontology
def: "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." []
subset: 3_STAR
synonym: "neurotransmitters" RELATED [ChEBI]
xref: Wikipedia:Neurotransmitter
is_a: CHEBI:33280 ! molecular messenger

[Term]
id: CHEBI:25555
name: nitrogen atom
namespace: chebi_ontology
subset: 3_STAR
synonym: "7N" RELATED [IUPAC]
synonym: "azote" RELATED [IUPAC]
synonym: "N" RELATED [IUPAC]
synonym: "nitrogen" EXACT IUPAC_NAME [IUPAC]
synonym: "nitrogen" RELATED [ChEBI]
synonym: "nitrogeno" RELATED [ChEBI]
synonym: "Stickstoff" RELATED [ChEBI]
xref: WebElements:N
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33300 ! pnictogen
relationship: has_role CHEBI:33937 ! macronutrient
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "14.007" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "14.00307" xsd:string

[Term]
id: CHEBI:25585
name: nonmetal atom
namespace: chebi_ontology
subset: 3_STAR
synonym: "Nichtmetall" RELATED [ChEBI]
synonym: "Nichtmetalle" RELATED [ChEBI]
synonym: "no metal" RELATED [ChEBI]
synonym: "no metales" RELATED [ChEBI]
synonym: "non-metal" RELATED [ChEBI]
synonym: "non-metaux" RELATED [ChEBI]
synonym: "nonmetal" EXACT IUPAC_NAME [IUPAC]
synonym: "nonmetal" RELATED [ChEBI]
synonym: "nonmetals" RELATED [ChEBI]
is_a: CHEBI:33250 ! atom

[Term]
id: CHEBI:25696
name: organic anion
namespace: chebi_ontology
def: "Any organic ion with a net negative charge." []
subset: 3_STAR
synonym: "organic anions" RELATED [ChEBI]
is_a: CHEBI:22563 ! anion
is_a: CHEBI:25699 ! organic ion

[Term]
id: CHEBI:25697
name: organic cation
namespace: chebi_ontology
def: "Any organic ion with a net positive charge." []
subset: 3_STAR
synonym: "organic cations" RELATED [ChEBI]
is_a: CHEBI:25699 ! organic ion
is_a: CHEBI:36916 ! cation

[Term]
id: CHEBI:25699
name: organic ion
namespace: chebi_ontology
subset: 3_STAR
synonym: "organic ions" RELATED [ChEBI]
is_a: CHEBI:24870 ! ion
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:25704
name: organic sulfate
namespace: chebi_ontology
def: "Compounds of the general formula SO3HOR where R is an organyl group" []
subset: 3_STAR
synonym: "organic sulfates" RELATED [ChEBI]
is_a: CHEBI:26820 ! sulfates
relationship: is_conjugate_acid_of CHEBI:58958 ! organosulfate oxoanion

[Term]
id: CHEBI:25741
name: oxide
namespace: chebi_ontology
def: "An oxide is a chemical compound of oxygen with other chemical elements." []
subset: 3_STAR
synonym: "oxide" EXACT [ChEBI]
synonym: "oxides" RELATED [ChEBI]
is_a: CHEBI:25806 ! oxygen molecular entity
is_a: CHEBI:37577 ! heteroatomic molecular entity

[Term]
id: CHEBI:25805
name: oxygen atom
namespace: chebi_ontology
subset: 3_STAR
synonym: "8O" RELATED [IUPAC]
synonym: "O" RELATED [IUPAC]
synonym: "oxigeno" RELATED [ChEBI]
synonym: "oxygen" EXACT IUPAC_NAME [IUPAC]
synonym: "oxygen" RELATED [ChEBI]
synonym: "oxygene" RELATED [ChEBI]
synonym: "Sauerstoff" RELATED [ChEBI]
xref: KEGG:C00007
xref: WebElements:O
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33303 ! chalcogen
relationship: has_role CHEBI:33937 ! macronutrient
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QVGXLLKOCUKJST-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O]" xsd:string

[Term]
id: CHEBI:25806
name: oxygen molecular entity
namespace: chebi_ontology
subset: 3_STAR
synonym: "oxygen molecular entities" RELATED [ChEBI]
synonym: "oxygen molecular entity" EXACT [ChEBI]
is_a: CHEBI:33304 ! chalcogen molecular entity
relationship: has_part CHEBI:25805 ! oxygen atom

[Term]
id: CHEBI:25905
name: peptide hormone
namespace: chebi_ontology
def: "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." []
subset: 3_STAR
synonym: "peptide hormones" RELATED [ChEBI]
synonym: "polypeptide hormone" RELATED [ChEBI]
is_a: CHEBI:16670 ! peptide
relationship: has_role CHEBI:24621 ! hormone

[Term]
id: CHEBI:26020
name: phosphate
namespace: chebi_ontology
def: "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." []
subset: 3_STAR
synonym: "phosphates" EXACT IUPAC_NAME [IUPAC]
synonym: "phosphates" RELATED [ChEBI]
is_a: CHEBI:26079 ! phosphoric acid derivative

[Term]
id: CHEBI:26078
name: phosphoric acid
namespace: chebi_ontology
def: "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." []
subset: 3_STAR
synonym: "[PO(OH)3]" RELATED [IUPAC]
synonym: "acide phosphorique" RELATED [ChEBI]
synonym: "acidum phosphoricum" RELATED [ChEBI]
synonym: "H3PO4" RELATED [IUPAC]
synonym: "Orthophosphoric acid" RELATED [KEGG_COMPOUND]
synonym: "orthophosphoric acid" RELATED [NIST_Chemistry_WebBook]
synonym: "Phosphate" RELATED [KEGG_COMPOUND]
synonym: "Phosphoric acid" EXACT [KEGG_COMPOUND]
synonym: "phosphoric acid" EXACT [IUPAC]
synonym: "Phosphorsaeure" RELATED [ChEBI]
synonym: "Phosphorsaeureloesungen" RELATED [ChEBI]
synonym: "tetraoxophosphoric acid" EXACT IUPAC_NAME [IUPAC]
synonym: "trihydrogen tetraoxophosphate(3-)" EXACT IUPAC_NAME [IUPAC]
synonym: "trihydroxidooxidophosphorus" EXACT IUPAC_NAME [IUPAC]
xref: Beilstein:1921286 {source="Beilstein"}
xref: CAS:7664-38-2 {source="NIST Chemistry WebBook"}
xref: CAS:7664-38-2 {source="KEGG COMPOUND"}
xref: CAS:7664-38-2 {source="ChemIDplus"}
xref: Drug_Central:4478 {source="DrugCentral"}
xref: Gmelin:2000 {source="Gmelin"}
xref: HMDB:HMDB0002142
xref: KEGG:C00009
xref: KEGG:D05467
xref: KNApSAcK:C00007408
xref: PMID:11455380 {source="Europe PMC"}
xref: PMID:15630224 {source="Europe PMC"}
xref: PMID:17439666 {source="Europe PMC"}
xref: PMID:17518491 {source="Europe PMC"}
xref: PMID:22282755 {source="Europe PMC"}
xref: PMID:22333268 {source="Europe PMC"}
xref: PMID:22381614 {source="Europe PMC"}
xref: PMID:22401268 {source="Europe PMC"}
xref: Reaxys:1921286 {source="Reaxys"}
xref: Wikipedia:Phosphoric_Acid
is_a: CHEBI:59698 ! phosphoric acids
relationship: has_role CHEBI:33287 ! fertilizer
relationship: has_role CHEBI:46787 ! solvent
relationship: has_role CHEBI:77746 ! human metabolite
relationship: has_role CHEBI:84735 ! algal metabolite
relationship: is_conjugate_acid_of CHEBI:39745 ! dihydrogenphosphate
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "H3O4P" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "97.99520" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.97690" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OP(=O)(O[H])O[H]" xsd:string

[Term]
id: CHEBI:26079
name: phosphoric acid derivative
namespace: chebi_ontology
subset: 1_STAR
is_a: CHEBI:36359 ! phosphorus oxoacid derivative
relationship: has_functional_parent CHEBI:26078 ! phosphoric acid

[Term]
id: CHEBI:26082
name: phosphorus molecular entity
namespace: chebi_ontology
subset: 3_STAR
synonym: "phosphorus molecular entities" RELATED [ChEBI]
is_a: CHEBI:33302 ! pnictogen molecular entity
relationship: has_part CHEBI:28659 ! phosphorus atom

[Term]
id: CHEBI:26708
name: sodium atom
namespace: chebi_ontology
subset: 3_STAR
synonym: "11Na" RELATED [IUPAC]
synonym: "Na" RELATED [IUPAC]
synonym: "Natrium" RELATED [ChemIDplus]
synonym: "natrium" RELATED [IUPAC]
synonym: "sodio" RELATED [ChemIDplus]
synonym: "sodium" EXACT IUPAC_NAME [IUPAC]
synonym: "sodium" RELATED [ChEBI]
xref: CAS:7440-23-5 {source="ChemIDplus"}
xref: Gmelin:16221 {source="Gmelin"}
xref: KEGG:C01330
xref: WebElements:Na
is_a: CHEBI:22314 ! alkali metal atom
relationship: has_role CHEBI:33937 ! macronutrient
relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "Na" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KEAYESYHFKHZAL-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "22.98977" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "22.98977" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na]" xsd:string

[Term]
id: CHEBI:26712
name: sodium molecular entity
namespace: chebi_ontology
subset: 3_STAR
synonym: "sodium compounds" RELATED [ChEBI]
synonym: "sodium molecular entities" RELATED [ChEBI]
is_a: CHEBI:33296 ! alkali metal molecular entity
relationship: has_part CHEBI:26708 ! sodium atom

[Term]
id: CHEBI:26714
name: sodium salt
namespace: chebi_ontology
def: "Any alkali metal salt having sodium(1+) as the cation." []
subset: 3_STAR
synonym: "Natriumsalz" RELATED [ChEBI]
synonym: "Natriumsalze" RELATED [ChEBI]
synonym: "sodium salts" RELATED [ChEBI]
is_a: CHEBI:26712 ! sodium molecular entity
is_a: CHEBI:35479 ! alkali metal salt
relationship: has_part CHEBI:29101 ! sodium(1+)

[Term]
id: CHEBI:26764
name: steroid hormone
namespace: chebi_ontology
def: "Any steroid that acts as hormone." []
subset: 3_STAR
synonym: "hormona esteroide" RELATED [ChEBI]
synonym: "hormonas esteroideas" RELATED [ChEBI]
synonym: "hormone steroide" RELATED [ChEBI]
synonym: "hormones steroides" RELATED [ChEBI]
synonym: "steroid hormones" RELATED [ChEBI]
synonym: "Steroidhormon" RELATED [ChEBI]
synonym: "Steroidhormone" RELATED [ChEBI]
is_a: CHEBI:35341 ! steroid
relationship: has_role CHEBI:24621 ! hormone

[Term]
id: CHEBI:26819
name: sulfuric ester
namespace: chebi_ontology
def: "An ester of an alcohol and sulfuric acid." []
subset: 3_STAR
synonym: "sulfate ester" RELATED [ChEBI]
synonym: "sulfuric acid ester" RELATED [ChEBI]
synonym: "sulfuric acid esters" RELATED [ChEBI]
is_a: CHEBI:35701 ! ester
is_a: CHEBI:37826 ! sulfuric acid derivative
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06300" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]OS(=O)(=O)O[*]" xsd:string

[Term]
id: CHEBI:26820
name: sulfates
namespace: chebi_ontology
def: "Salts and esters of sulfuric acid" []
subset: 3_STAR
synonym: "sulfates" EXACT [ChEBI]
synonym: "sulfuric acid derivative" RELATED [ChEBI]
synonym: "sulphates" RELATED [ChEBI]
is_a: CHEBI:37826 ! sulfuric acid derivative

[Term]
id: CHEBI:26833
name: sulfur atom
namespace: chebi_ontology
subset: 3_STAR
synonym: "16S" RELATED [IUPAC]
synonym: "azufre" RELATED [ChEBI]
synonym: "Elemental sulfur" RELATED [KEGG_COMPOUND]
synonym: "S" RELATED [KEGG_COMPOUND]
synonym: "S" RELATED [IUPAC]
synonym: "Schwefel" RELATED [ChEBI]
synonym: "soufre" RELATED [ChEBI]
synonym: "sulfur" EXACT IUPAC_NAME [IUPAC]
synonym: "sulfur" RELATED [ChEBI]
synonym: "sulfur" RELATED [UniProt]
synonym: "sulphur" RELATED [ChEBI]
synonym: "theion" RELATED [IUPAC]
xref: CAS:7704-34-9 {source="ChemIDplus"}
xref: CAS:7704-34-9 {source="NIST Chemistry WebBook"}
xref: KEGG:C00087
xref: KEGG:D06527
xref: PPDB:605
xref: WebElements:S
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33303 ! chalcogen
relationship: has_role CHEBI:33937 ! macronutrient
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "S" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/S" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NINIDFKCEFEMDL-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "32.06600" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.97207" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[S]" xsd:string

[Term]
id: CHEBI:26835
name: sulfur molecular entity
namespace: chebi_ontology
subset: 3_STAR
synonym: "sulfur molecular entities" RELATED [ChEBI]
synonym: "sulfur molecular entity" EXACT [ChEBI]
is_a: CHEBI:33304 ! chalcogen molecular entity
relationship: has_part CHEBI:26833 ! sulfur atom

[Term]
id: CHEBI:26836
name: sulfuric acid
namespace: chebi_ontology
def: "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." []
subset: 3_STAR
synonym: "[S(OH)2O2]" RELATED [MolBase]
synonym: "[SO2(OH)2]" RELATED [IUPAC]
synonym: "Acide sulfurique" RELATED [ChemIDplus]
synonym: "Acido sulfurico" RELATED [ChemIDplus]
synonym: "Acidum sulfuricum" RELATED [ChemIDplus]
synonym: "dihydrogen tetraoxosulfate" EXACT IUPAC_NAME [IUPAC]
synonym: "dihydroxidodioxidosulfur" EXACT IUPAC_NAME [IUPAC]
synonym: "H2SO4" RELATED [IUPAC]
synonym: "hydrogen tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydrogen tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC]
synonym: "Schwefelsaeureloesungen" RELATED [ChemIDplus]
synonym: "Sulfuric acid" EXACT [KEGG_COMPOUND]
synonym: "sulfuric acid" EXACT IUPAC_NAME [IUPAC]
synonym: "sulfuric acid" EXACT [ChEBI]
synonym: "sulphuric acid" RELATED [MolBase]
synonym: "tetraoxosulfuric acid" EXACT IUPAC_NAME [IUPAC]
xref: CAS:7664-93-9 {source="ChemIDplus"}
xref: CAS:7664-93-9 {source="KEGG COMPOUND"}
xref: CAS:7664-93-9 {source="NIST Chemistry WebBook"}
xref: Gmelin:2122 {source="Gmelin"}
xref: KEGG:C00059
xref: KEGG:D05963
xref: KNApSAcK:C00007530
xref: MolBase:4
xref: PMID:13568755 {source="Europe PMC"}
xref: PMID:16122922 {source="Europe PMC"}
xref: PMID:19397353 {source="Europe PMC"}
xref: PMID:22047659 {source="Europe PMC"}
xref: PMID:22136045 {source="Europe PMC"}
xref: PMID:22204399 {source="Europe PMC"}
xref: PMID:22267186 {source="Europe PMC"}
xref: PMID:22296037 {source="Europe PMC"}
xref: PMID:22364556 {source="Europe PMC"}
xref: PMID:22435616 {source="Europe PMC"}
xref: PPDB:606
xref: Reaxys:2037554 {source="Reaxys"}
xref: Wikipedia:Sulfuric_acid
is_a: CHEBI:33402 ! sulfur oxoacid
relationship: has_role CHEBI:35223 ! catalyst
relationship: is_conjugate_acid_of CHEBI:45696 ! hydrogensulfate
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O4S" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "98.07948" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.96738" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OS(=O)(=O)O[H]" xsd:string

[Term]
id: CHEBI:26932
name: tetrapyrrole
namespace: chebi_ontology
def: "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." []
subset: 3_STAR
synonym: "a tetrapyrrole" RELATED [UniProt]
synonym: "tetrapyrrole" EXACT IUPAC_NAME [IUPAC]
synonym: "tetrapyrroles" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:33833 ! heteroarene
is_a: CHEBI:38077 ! polypyrrole

[Term]
id: CHEBI:27027
name: micronutrient
namespace: chebi_ontology
def: "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." []
subset: 3_STAR
synonym: "micronutrients" RELATED [ChEBI]
synonym: "trace elements" RELATED [ChEBI]
xref: Wikipedia:Micronutrient
is_a: CHEBI:33284 ! nutrient

[Term]
id: CHEBI:27162
name: tryptamines
namespace: chebi_ontology
def: "Tryptamine and its substitution derivatives." []
subset: 3_STAR
is_a: CHEBI:24828 ! indoles

[Term]
id: CHEBI:27171
name: organic heterobicyclic compound
namespace: chebi_ontology
subset: 3_STAR
synonym: "heterobicyclic compounds" RELATED [ChEBI]
synonym: "organic heterobicyclic compounds" RELATED [ChEBI]
is_a: CHEBI:33672 ! heterobicyclic compound
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:27207
name: univalent carboacyl group
namespace: chebi_ontology
def: "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." []
subset: 3_STAR
synonym: "univalent acyl group" RELATED [ChEBI]
synonym: "univalent carboacyl groups" RELATED [ChEBI]
synonym: "univalent carboxylic acyl groups" RELATED [ChEBI]
is_a: CHEBI:37838 ! carboacyl group

[Term]
id: CHEBI:27369
name: zwitterion
namespace: chebi_ontology
def: "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." []
subset: 3_STAR
synonym: "compose zwitterionique" RELATED [IUPAC]
synonym: "compuestos zwitterionicos" RELATED [IUPAC]
synonym: "zwitterion" EXACT IUPAC_NAME [IUPAC]
synonym: "zwitteriones" RELATED [IUPAC]
synonym: "zwitterionic compounds" RELATED [IUPAC]
synonym: "zwitterions" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:51151 ! dipolar compound

[Term]
id: CHEBI:27594
name: carbon atom
namespace: chebi_ontology
alt_id: CHEBI:23009
alt_id: CHEBI:3399
subset: 3_STAR
synonym: "6C" RELATED [IUPAC]
synonym: "C" RELATED [KEGG_COMPOUND]
synonym: "C" RELATED [IUPAC]
synonym: "Carbon" RELATED [KEGG_COMPOUND]
synonym: "carbon" EXACT IUPAC_NAME [IUPAC]
synonym: "carbon" RELATED [ChEBI]
synonym: "carbone" RELATED [ChEBI]
synonym: "carbonium" RELATED [ChEBI]
synonym: "carbono" RELATED [ChEBI]
synonym: "Kohlenstoff" RELATED [ChEBI]
xref: CAS:7440-44-0 {source="ChemIDplus"}
xref: CAS:7440-44-0 {source="KEGG COMPOUND"}
xref: KEGG:C06265
xref: WebElements:C
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33306 ! carbon group element atom
relationship: has_role CHEBI:33937 ! macronutrient
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OKTJSMMVPCPJKN-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "12.01070" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "12.00000" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[C]" xsd:string

[Term]
id: CHEBI:28087
name: glycogen
namespace: chebi_ontology
alt_id: CHEBI:24379
alt_id: CHEBI:5466
def: "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues." []
subset: 3_STAR
synonym: "animal starch" RELATED [ChemIDplus]
synonym: "Glycogen" EXACT [KEGG_COMPOUND]
synonym: "liver starch" RELATED [ChemIDplus]
synonym: "WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1" RELATED [GlyTouCan]
xref: CAS:9005-79-2 {source="KEGG COMPOUND"}
xref: CAS:9005-79-2 {source="ChemIDplus"}
xref: GlyGen:G99991IU
xref: GlyTouCan:G99991IU
xref: HMDB:HMDB0000757
xref: KEGG:C00182
xref: MetaCyc:CPD0-971
xref: Wikipedia:Glycogen
is_a: CHEBI:24384 ! glycogens
relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite
relationship: has_role CHEBI:76971 ! Escherichia coli metabolite

[Term]
id: CHEBI:28616
name: carbamic acid
namespace: chebi_ontology
alt_id: CHEBI:22504
alt_id: CHEBI:23002
alt_id: CHEBI:3386
alt_id: CHEBI:44573
def: "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." []
subset: 3_STAR
synonym: "Aminoameisensaeure" RELATED [ChEBI]
synonym: "Aminoformic acid" RELATED [KEGG_COMPOUND]
synonym: "Carbamate" RELATED [KEGG_COMPOUND]
synonym: "CARBAMIC ACID" EXACT [PDBeChem]
synonym: "Carbamic acid" EXACT [KEGG_COMPOUND]
synonym: "carbamic acid" EXACT IUPAC_NAME [IUPAC]
synonym: "Carbamidsaeure" RELATED [ChEBI]
xref: Beilstein:1734754 {source="Beilstein"}
xref: CAS:463-77-4 {source="KEGG COMPOUND"}
xref: CAS:463-77-4 {source="ChemIDplus"}
xref: DrugBank:DB04261
xref: Gmelin:130345 {source="Gmelin"}
xref: KEGG:C01563
xref: PDBeChem:OUT
xref: Wikipedia:Carbamic_acid
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:35605 ! carbon oxoacid
is_a: CHEBI:64708 ! one-carbon compound
relationship: has_role CHEBI:76971 ! Escherichia coli metabolite
relationship: is_conjugate_acid_of CHEBI:13941 ! carbamate
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3NO2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "61.04006" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "61.01638" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(O)=O" xsd:string

[Term]
id: CHEBI:28659
name: phosphorus atom
namespace: chebi_ontology
alt_id: CHEBI:26080
alt_id: CHEBI:8168
subset: 3_STAR
synonym: "15P" RELATED [IUPAC]
synonym: "fosforo" RELATED [ChEBI]
synonym: "P" RELATED [IUPAC]
synonym: "P" RELATED [KEGG_COMPOUND]
synonym: "Phosphor" RELATED [ChEBI]
synonym: "phosphore" RELATED [ChEBI]
synonym: "Phosphorus" RELATED [KEGG_COMPOUND]
synonym: "phosphorus" EXACT IUPAC_NAME [IUPAC]
synonym: "phosphorus" RELATED [ChEBI]
xref: CAS:7723-14-0 {source="ChemIDplus"}
xref: CAS:7723-14-0 {source="KEGG COMPOUND"}
xref: Gmelin:16235 {source="Gmelin"}
xref: KEGG:C06262
xref: WebElements:P
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33300 ! pnictogen
relationship: has_role CHEBI:33937 ! macronutrient
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "P" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/P" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OAICVXFJPJFONN-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "30.97376" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "30.97376" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[P]" xsd:string

[Term]
id: CHEBI:28790
name: serotonin
namespace: chebi_ontology
alt_id: CHEBI:1420
alt_id: CHEBI:26652
alt_id: CHEBI:49894
def: "A primary amino compound that is the 5-hydroxy derivative of tryptamine." []
subset: 3_STAR
synonym: "3-(2-Aminoethyl)-1H-indol-5-ol" RELATED [KEGG_COMPOUND]
synonym: "3-(2-aminoethyl)-1H-indol-5-ol" EXACT IUPAC_NAME [IUPAC]
synonym: "5-HT" RELATED [IUPHAR]
synonym: "5-Hydroxytryptamine" RELATED [KEGG_COMPOUND]
synonym: "Enteramine" RELATED [KEGG_COMPOUND]
synonym: "SEROTONIN" EXACT [PDBeChem]
synonym: "Serotonin" EXACT [KEGG_COMPOUND]
synonym: "serotonine" RELATED [ChEBI]
synonym: "thrombocytin" RELATED [ChemIDplus]
synonym: "thrombotonin" RELATED [ChemIDplus]
xref: Beilstein:143524 {source="Beilstein"}
xref: CAS:50-67-9 {source="KEGG COMPOUND"}
xref: CAS:50-67-9 {source="ChemIDplus"}
xref: Gmelin:1861995 {source="Gmelin"}
xref: HMDB:HMDB0000259
xref: KEGG:C00780
xref: KNApSAcK:C00001429
xref: LINCS:LSM-6589
xref: MetaCyc:SEROTONIN
xref: PDBeChem:SRO
xref: PMID:18593914 {source="Europe PMC"}
xref: PMID:22770225 {source="Europe PMC"}
xref: PMID:24136337 {source="Europe PMC"}
xref: Reaxys:143524 {source="Reaxys"}
xref: Wikipedia:Serotonin
is_a: CHEBI:25375 ! monoamine molecular messenger
is_a: CHEBI:27162 ! tryptamines
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:50994 ! primary amino compound
is_a: CHEBI:84729 ! hydroxyindoles
relationship: has_functional_parent CHEBI:16765 ! tryptamine
relationship: has_role CHEBI:25512 ! neurotransmitter
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_base_of CHEBI:350546 ! serotonin(1+)
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H12N2O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "176.215" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "176.09496" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=CC(=CC=2C(=CNC12)CCN)O" xsd:string

[Term]
id: CHEBI:28938
name: ammonium
namespace: chebi_ontology
alt_id: CHEBI:22534
alt_id: CHEBI:49783
alt_id: CHEBI:7435
def: "An onium cation obtained by protonation of ammonia." []
subset: 3_STAR
synonym: "[NH4](+)" RELATED [MolBase]
synonym: "ammonium" EXACT IUPAC_NAME [IUPAC]
synonym: "ammonium" EXACT [ChEBI]
synonym: "ammonium cation" RELATED [ChemIDplus]
synonym: "ammonium ion" RELATED [PDBeChem]
synonym: "Ammonium(1+)" RELATED [ChemIDplus]
synonym: "azanium" EXACT IUPAC_NAME [IUPAC]
synonym: "NH4(+)" RELATED [UniProt]
synonym: "NH4(+)" RELATED [IUPAC]
synonym: "NH4+" RELATED [KEGG_COMPOUND]
xref: CAS:14798-03-9 {source="NIST Chemistry WebBook"}
xref: CAS:14798-03-9 {source="ChemIDplus"}
xref: Gmelin:84 {source="Gmelin"}
xref: KEGG:C01342
xref: MetaCyc:AMMONIUM
xref: MolBase:929
xref: PDBeChem:NH4
xref: PMID:11319011 {source="Europe PMC"}
xref: PMID:11341317 {source="Europe PMC"}
xref: PMID:12096804 {source="Europe PMC"}
xref: PMID:14512268 {source="Europe PMC"}
xref: PMID:14879753 {source="Europe PMC"}
xref: PMID:16345391 {source="Europe PMC"}
xref: PMID:16903292 {source="Europe PMC"}
xref: PMID:17392693 {source="Europe PMC"}
xref: PMID:18515490 {source="Europe PMC"}
xref: PMID:19199063 {source="Europe PMC"}
xref: PMID:19596600 {source="Europe PMC"}
xref: PMID:19682559 {source="Europe PMC"}
xref: PMID:19716251 {source="Europe PMC"}
xref: PMID:21993530 {source="Europe PMC"}
xref: PMID:22265469 {source="Europe PMC"}
xref: PMID:22524020 {source="Europe PMC"}
xref: PMID:22562341 {source="Europe PMC"}
xref: PMID:22631217 {source="Europe PMC"}
xref: Reaxys:16093784 {source="Reaxys"}
xref: Wikipedia:Ammonium
is_a: CHEBI:35106 ! nitrogen hydride
is_a: CHEBI:50313 ! onium cation
is_a: CHEBI:60242 ! monovalent inorganic cation
relationship: has_role CHEBI:23357 ! cofactor
relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite
relationship: has_role CHEBI:76971 ! Escherichia coli metabolite
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_acid_of CHEBI:16134 ! ammonia
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "H4N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3N/h1H3/p+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "18.03850" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "18.03383" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N+]([H])([H])[H]" xsd:string

[Term]
id: CHEBI:28963
name: amino sugar
namespace: chebi_ontology
alt_id: CHEBI:22481
alt_id: CHEBI:22530
alt_id: CHEBI:2662
def: "Any sugar having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups." []
subset: 3_STAR
synonym: "amino sugars" RELATED [ChEBI]
synonym: "aminosugar" RELATED [ChEBI]
synonym: "Aminosugars" RELATED [KEGG_COMPOUND]
xref: KEGG:C05383
xref: PMID:18424273 {source="Europe PMC"}
xref: PMID:9056391 {source="Europe PMC"}
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:28965
name: dicarboxylic acid dianion
namespace: chebi_ontology
alt_id: CHEBI:13632
alt_id: CHEBI:23688
alt_id: CHEBI:23689
alt_id: CHEBI:38711
def: "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." []
subset: 3_STAR
synonym: "a dicarboxylate" RELATED [UniProt]
synonym: "dicarboxylate" RELATED [ChEBI]
synonym: "dicarboxylates" RELATED [ChEBI]
synonym: "dicarboxylic acid dianion" EXACT [ChEBI]
synonym: "dicarboxylic acid dianions" RELATED [ChEBI]
is_a: CHEBI:35693 ! dicarboxylic acid anion
is_a: CHEBI:38716 ! carboxylic acid dianion
property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C2O4R" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "88.019" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "87.97966" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C(=O)[*]C([O-])=O" xsd:string

[Term]
id: CHEBI:28976
name: carbonic acid
namespace: chebi_ontology
alt_id: CHEBI:13351
alt_id: CHEBI:23017
alt_id: CHEBI:23744
alt_id: CHEBI:3401
subset: 3_STAR
synonym: "[CO(OH)2]" RELATED [IUPAC]
synonym: "Carbonic acid" EXACT [KEGG_COMPOUND]
synonym: "carbonic acid" EXACT IUPAC_NAME [IUPAC]
synonym: "Dihydrogen carbonate" RELATED [KEGG_COMPOUND]
synonym: "dihydroxidooxidocarbon" EXACT IUPAC_NAME [IUPAC]
synonym: "H2CO3" RELATED [KEGG_COMPOUND]
synonym: "H2CO3" RELATED [IUPAC]
synonym: "Koehlensaeure" RELATED [ChEBI]
xref: CAS:463-79-6 {source="ChemIDplus"}
xref: CAS:463-79-6 {source="KEGG COMPOUND"}
xref: Gmelin:25554 {source="Gmelin"}
xref: KEGG:C01353
xref: PDBeChem:CO3
is_a: CHEBI:35605 ! carbon oxoacid
is_a: CHEBI:36961 ! chalcocarbonic acid
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: is_conjugate_acid_of CHEBI:17544 ! hydrogencarbonate
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2O3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "62.02478" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "62.00039" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC(O)=O" xsd:string

[Term]
id: CHEBI:29067
name: carboxylic acid anion
namespace: chebi_ontology
alt_id: CHEBI:13626
alt_id: CHEBI:13945
alt_id: CHEBI:23026
alt_id: CHEBI:58657
def: "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." []
subset: 3_STAR
synonym: "a carboxylate" RELATED [UniProt]
synonym: "carboxylic acid anions" RELATED [ChEBI]
synonym: "carboxylic anions" RELATED [ChEBI]
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:35406 ! oxoanion
relationship: is_conjugate_base_of CHEBI:33575 ! carboxylic acid
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "44.00950" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string

[Term]
id: CHEBI:29101
name: sodium(1+)
namespace: chebi_ontology
alt_id: CHEBI:26717
alt_id: CHEBI:49766
alt_id: CHEBI:9175
def: "A monoatomic monocation obtained from sodium." []
subset: 3_STAR
synonym: "Na(+)" RELATED [UniProt]
synonym: "Na(+)" RELATED [IUPAC]
synonym: "Na+" RELATED [KEGG_COMPOUND]
synonym: "sodium cation" EXACT IUPAC_NAME [IUPAC]
synonym: "SODIUM ION" RELATED [PDBeChem]
synonym: "sodium(1+)" EXACT IUPAC_NAME [IUPAC]
synonym: "sodium(1+) ion" EXACT IUPAC_NAME [IUPAC]
synonym: "sodium(I) cation" EXACT IUPAC_NAME [IUPAC]
xref: CAS:17341-25-2 {source="ChemIDplus"}
xref: CAS:17341-25-2 {source="NIST Chemistry WebBook"}
xref: Gmelin:15196 {source="Gmelin"}
xref: KEGG:C01330
xref: PDBeChem:NA
is_a: CHEBI:25414 ! monoatomic monocation
is_a: CHEBI:33504 ! alkali metal cation
is_a: CHEBI:37246 ! elemental sodium
is_a: CHEBI:60242 ! monovalent inorganic cation
relationship: has_role CHEBI:23357 ! cofactor
relationship: has_role CHEBI:77746 ! human metabolite
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "Na" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na/q+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "FKNQFGJONOIPTF-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "22.98977" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "22.98922" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na+]" xsd:string

[Term]
id: CHEBI:29337
name: azanide
namespace: chebi_ontology
subset: 3_STAR
synonym: "amide" EXACT IUPAC_NAME [IUPAC]
synonym: "azanide" EXACT IUPAC_NAME [IUPAC]
synonym: "dihydridonitrate(1-)" EXACT IUPAC_NAME [IUPAC]
synonym: "NH2(-)" RELATED [IUPAC]
is_a: CHEBI:35106 ! nitrogen hydride
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: is_conjugate_acid_of CHEBI:29340 ! hydridonitrate(2-)
relationship: is_conjugate_base_of CHEBI:16134 ! ammonia
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "H2N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2N/h1H2/q-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "HYGWNUKOUCZBND-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "16.02262" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "16.01927" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N-][H]" xsd:string

[Term]
id: CHEBI:29340
name: hydridonitrate(2-)
namespace: chebi_ontology
def: "A divalent inorganic anion resulting from the removal of two protons from ammonia." []
subset: 3_STAR
synonym: "azanediide" EXACT IUPAC_NAME [IUPAC]
synonym: "hydridonitrate(2-)" EXACT IUPAC_NAME [IUPAC]
synonym: "imide" RELATED [IUPAC]
synonym: "NH(2-)" RELATED [IUPAC]
is_a: CHEBI:35106 ! nitrogen hydride
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: is_conjugate_base_of CHEBI:29337 ! azanide
property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "HN" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/HN/h1H/q-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DZQYTNGKSBCIOE-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "15.01468" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.01200" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[N--][H]" xsd:string

[Term]
id: CHEBI:29793
name: hydridodioxygen(1+)
namespace: chebi_ontology
subset: 3_STAR
synonym: "[HO2](+)" RELATED [ChEBI]
synonym: "dioxidenium" EXACT IUPAC_NAME [IUPAC]
synonym: "HO2(+)" RELATED [IUPAC]
synonym: "HOO(+)" RELATED [ChEBI]
synonym: "hydridodioxygen(1+)" EXACT IUPAC_NAME [IUPAC]
xref: Gmelin:508 {source="Gmelin"}
is_a: CHEBI:33693 ! oxygen hydride
relationship: is_conjugate_acid_of CHEBI:15379 ! dioxygen
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "HO2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O2/c1-2/p+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MYMOFIZGZYHOMD-UHFFFAOYSA-O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "33.00674" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "32.99711" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][O+]=O" xsd:string

[Term]
id: CHEBI:30089
name: acetate
namespace: chebi_ontology
alt_id: CHEBI:13704
alt_id: CHEBI:22165
alt_id: CHEBI:40480
def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." []
subset: 3_STAR
synonym: "acetate" EXACT [UniProt]
synonym: "acetate" EXACT IUPAC_NAME [IUPAC]
synonym: "ACETATE ION" RELATED [PDBeChem]
synonym: "acetic acid, ion(1-)" RELATED [ChemIDplus]
synonym: "Azetat" RELATED [ChEBI]
synonym: "CH3-COO(-)" RELATED [IUPAC]
synonym: "Ethanoat" RELATED [ChEBI]
synonym: "ethanoate" RELATED [ChEBI]
synonym: "MeCO2 anion" RELATED [NIST_Chemistry_WebBook]
xref: Beilstein:1901470 {source="Beilstein"}
xref: CAS:71-50-1 {source="ChemIDplus"}
xref: CAS:71-50-1 {source="NIST Chemistry WebBook"}
xref: DrugBank:DB03166
xref: Gmelin:1379 {source="Gmelin"}
xref: KEGG:C00033
xref: MetaCyc:ACET
xref: PDBeChem:ACT
xref: PMID:17190852 {source="Europe PMC"}
xref: PMID:22211106 {source="Europe PMC"}
xref: PMID:22371380 {source="Europe PMC"}
xref: Reaxys:1901470 {source="Reaxys"}
xref: UM-BBD_compID:c0050 {source="UM-BBD"}
xref: Wikipedia:Acetate
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_base_of CHEBI:15366 ! acetic acid
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3O2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-M" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "59.04402" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.01385" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC([O-])=O" xsd:string

[Term]
id: CHEBI:30212
name: photon
namespace: chebi_ontology
alt_id: CHEBI:10581
alt_id: CHEBI:14383
def: "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force." []
subset: 3_STAR
synonym: "foton" RELATED [ChEBI]
synonym: "gamma" RELATED [IUPAC]
synonym: "hnu" RELATED [IUPAC]
synonym: "hnu" RELATED [UniProt]
synonym: "Lichtquant" RELATED [ChEBI]
synonym: "Light" RELATED [KEGG_COMPOUND]
synonym: "light quantum" RELATED [ChEBI]
synonym: "photon" EXACT IUPAC_NAME [IUPAC]
xref: KEGG:C00205
is_a: CHEBI:36341 ! boson
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "0.0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "0.0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "*" xsd:string

[Term]
id: CHEBI:3098
name: bile acid
namespace: chebi_ontology
def: "Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration." []
subset: 3_STAR
synonym: "5beta-bile acid" RELATED [ChEBI]
synonym: "5beta-bile acids" RELATED [ChEBI]
synonym: "Bile acid" EXACT [KEGG_COMPOUND]
synonym: "bile acids" RELATED [ChEBI]
synonym: "Bile salt" RELATED [KEGG_COMPOUND]
synonym: "Gallensaeure" RELATED [ChEBI]
synonym: "Gallensaeuren" RELATED [ChEBI]
xref: KEGG:C01558
is_a: CHEBI:138366 ! bile acids
is_a: CHEBI:24663 ! hydroxy-5beta-cholanic acid

[Term]
id: CHEBI:32952
name: amine
namespace: chebi_ontology
alt_id: CHEBI:13814
alt_id: CHEBI:22474
alt_id: CHEBI:2641
def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." []
subset: 3_STAR
synonym: "Amin" RELATED [ChEBI]
synonym: "Amine" EXACT [KEGG_COMPOUND]
synonym: "amines" EXACT IUPAC_NAME [IUPAC]
synonym: "Substituted amine" RELATED [KEGG_COMPOUND]
xref: KEGG:C00706
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:32988
name: amide
namespace: chebi_ontology
alt_id: CHEBI:22473
alt_id: CHEBI:2633
def: "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." []
subset: 3_STAR
synonym: "Amide" EXACT [KEGG_COMPOUND]
synonym: "amides" EXACT IUPAC_NAME [IUPAC]
xref: KEGG:C00241
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:33232
name: application
namespace: chebi_ontology
def: "Intended use of the molecular entity or part thereof by humans." []
subset: 3_STAR
is_a: CHEBI:50906 ! role

[Term]
id: CHEBI:33233
name: fundamental particle
namespace: chebi_ontology
def: "A particle not known to have substructure." []
subset: 3_STAR
synonym: "elementary particle" EXACT IUPAC_NAME [IUPAC]
synonym: "elementary particles" RELATED [ChEBI]
is_a: CHEBI:36342 ! subatomic particle

[Term]
id: CHEBI:33238
name: monoatomic entity
namespace: chebi_ontology
def: "A monoatomic entity is a molecular entity consisting of a single atom." []
subset: 3_STAR
synonym: "atomic entity" RELATED [ChEBI]
synonym: "monoatomic entities" RELATED [ChEBI]
is_a: CHEBI:33259 ! elemental molecular entity

[Term]
id: CHEBI:33241
name: oxoacid derivative
namespace: chebi_ontology
subset: 3_STAR
synonym: "oxoacid derivatives" RELATED [ChEBI]
is_a: CHEBI:37577 ! heteroatomic molecular entity
relationship: has_functional_parent CHEBI:24833 ! oxoacid

[Term]
id: CHEBI:33242
name: inorganic hydride
namespace: chebi_ontology
subset: 3_STAR
synonym: "inorganic hydrides" RELATED [ChEBI]
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:33692 ! hydrides

[Term]
id: CHEBI:33245
name: organic fundamental parent
namespace: chebi_ontology
def: "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." []
subset: 3_STAR
synonym: "organic fundamental parents" RELATED [ChEBI]
synonym: "organic parent hydrides" RELATED [ChEBI]
is_a: CHEBI:37175 ! organic hydride
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33246
name: inorganic group
namespace: chebi_ontology
def: "Any substituent group which does not contain carbon." []
subset: 3_STAR
synonym: "inorganic groups" RELATED [ChEBI]
is_a: CHEBI:24433 ! group

[Term]
id: CHEBI:33247
name: organic group
namespace: chebi_ontology
def: "Any substituent group or skeleton containing carbon." []
subset: 3_STAR
synonym: "organic groups" RELATED [ChEBI]
is_a: CHEBI:23367 ! molecular entity
is_a: CHEBI:24433 ! group
relationship: is_substituent_group_from CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33249
name: organyl group
namespace: chebi_ontology
def: "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." []
subset: 3_STAR
synonym: "groupe organyle" RELATED [IUPAC]
synonym: "grupo organilo" RELATED [IUPAC]
synonym: "grupos organilo" RELATED [IUPAC]
synonym: "organyl group" EXACT IUPAC_NAME [IUPAC]
synonym: "organyl groups" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:51447 ! organic univalent group

[Term]
id: CHEBI:33250
name: atom
namespace: chebi_ontology
alt_id: CHEBI:22671
alt_id: CHEBI:23907
def: "A chemical entity constituting the smallest component of an element having the chemical properties of the element." []
subset: 3_STAR
synonym: "atom" EXACT IUPAC_NAME [IUPAC]
synonym: "atome" RELATED [IUPAC]
synonym: "atomo" RELATED [IUPAC]
synonym: "atoms" RELATED [ChEBI]
synonym: "atomus" RELATED [ChEBI]
synonym: "element" RELATED [ChEBI]
synonym: "elements" RELATED [ChEBI]
is_a: CHEBI:24431 ! chemical entity
relationship: has_part CHEBI:10545 ! electron
relationship: has_part CHEBI:33252 ! atomic nucleus

[Term]
id: CHEBI:33252
name: atomic nucleus
namespace: chebi_ontology
def: "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." []
subset: 3_STAR
synonym: "Atomkern" RELATED [ChEBI]
synonym: "Kern" RELATED [ChEBI]
synonym: "noyau" RELATED [IUPAC]
synonym: "noyau atomique" RELATED [ChEBI]
synonym: "nuclei" RELATED [ChEBI]
synonym: "nucleo" RELATED [IUPAC]
synonym: "nucleo atomico" RELATED [ChEBI]
synonym: "nucleus" EXACT IUPAC_NAME [IUPAC]
synonym: "nucleus atomi" RELATED [ChEBI]
is_a: CHEBI:36347 ! nuclear particle
relationship: has_part CHEBI:33253 ! nucleon

[Term]
id: CHEBI:33253
name: nucleon
namespace: chebi_ontology
def: "Heavy nuclear particle: proton or neutron." []
subset: 3_STAR
synonym: "nucleon" EXACT [IUPAC]
synonym: "nucleon" EXACT IUPAC_NAME [IUPAC]
synonym: "nucleons" RELATED [ChEBI]
synonym: "Nukleon" RELATED [ChEBI]
synonym: "Nukleonen" RELATED [ChEBI]
is_a: CHEBI:36339 ! baryon
is_a: CHEBI:36347 ! nuclear particle

[Term]
id: CHEBI:33256
name: primary amide
namespace: chebi_ontology
def: "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." []
subset: 3_STAR
synonym: "primary amide" EXACT [IUPAC]
synonym: "primary amides" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:32988 ! amide

[Term]
id: CHEBI:33259
name: elemental molecular entity
namespace: chebi_ontology
def: "A molecular entity all atoms of which have the same atomic number." []
subset: 3_STAR
synonym: "homoatomic entity" RELATED [ChEBI]
synonym: "homoatomic molecular entities" RELATED [ChEBI]
synonym: "homoatomic molecular entity" RELATED [ChEBI]
is_a: CHEBI:23367 ! molecular entity

[Term]
id: CHEBI:33262
name: elemental oxygen
namespace: chebi_ontology
subset: 3_STAR
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:25806 ! oxygen molecular entity
is_a: CHEBI:33259 ! elemental molecular entity

[Term]
id: CHEBI:33263
name: diatomic oxygen
namespace: chebi_ontology
subset: 3_STAR
is_a: CHEBI:33262 ! elemental oxygen
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "O2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "31.999" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.98983" xsd:string

[Term]
id: CHEBI:33273
name: polyatomic anion
namespace: chebi_ontology
def: "An anion consisting of more than one atom." []
subset: 3_STAR
synonym: "polyatomic anions" RELATED [ChEBI]
is_a: CHEBI:22563 ! anion
is_a: CHEBI:36358 ! polyatomic ion

[Term]
id: CHEBI:33280
name: molecular messenger
namespace: chebi_ontology
subset: 3_STAR
synonym: "chemical messenger" RELATED [ChEBI]
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:33281
name: antimicrobial agent
namespace: chebi_ontology
alt_id: CHEBI:22582
def: "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." []
subset: 3_STAR
synonym: "antibiotic" RELATED [ChEBI]
synonym: "antibiotics" RELATED [ChEBI]
synonym: "Antibiotika" RELATED [ChEBI]
synonym: "Antibiotikum" RELATED [ChEBI]
synonym: "antibiotique" RELATED [IUPAC]
synonym: "antimicrobial" RELATED [ChEBI]
synonym: "antimicrobial agents" RELATED [ChEBI]
synonym: "antimicrobials" RELATED [ChEBI]
synonym: "microbicide" RELATED [ChEBI]
synonym: "microbicides" RELATED [ChEBI]
xref: PMID:12964249 {source="Europe PMC"}
xref: PMID:22117953 {source="Europe PMC"}
xref: PMID:22439833 {source="Europe PMC"}
xref: PMID:22849268 {source="Europe PMC"}
xref: PMID:22849276 {source="Europe PMC"}
xref: PMID:22958833 {source="Europe PMC"}
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:33284
name: nutrient
namespace: chebi_ontology
def: "A nutrient is a food component that an organism uses to survive and grow." []
subset: 3_STAR
synonym: "nutrients" RELATED [ChEBI]
is_a: CHEBI:78295 ! food component

[Term]
id: CHEBI:33285
name: heteroorganic entity
namespace: chebi_ontology
def: "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." []
subset: 3_STAR
synonym: "heteroorganic entities" RELATED [ChEBI]
synonym: "organoelement compounds" RELATED [ChEBI]
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33286
name: agrochemical
namespace: chebi_ontology
def: "An agrochemical is a substance that is used in agriculture or horticulture." []
subset: 3_STAR
synonym: "agrichemical" RELATED [ChEBI]
synonym: "agrichemicals" RELATED [ChEBI]
synonym: "agricultural chemicals" RELATED [ChEBI]
synonym: "agrochemicals" RELATED [ChEBI]
xref: Wikipedia:Agrochemical
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:33287
name: fertilizer
namespace: chebi_ontology
def: "A fertilizer is any substance that is added to soil or water to assist the growth of plants." []
subset: 3_STAR
synonym: "fertiliser" RELATED [ChEBI]
synonym: "fertilizers" RELATED [ChEBI]
is_a: CHEBI:33286 ! agrochemical

[Term]
id: CHEBI:33296
name: alkali metal molecular entity
namespace: chebi_ontology
def: "A molecular entity containing one or more atoms of an alkali metal." []
subset: 3_STAR
synonym: "alkali metal molecular entities" RELATED [ChEBI]
is_a: CHEBI:33674 ! s-block molecular entity
relationship: has_part CHEBI:22314 ! alkali metal atom

[Term]
id: CHEBI:33300
name: pnictogen
namespace: chebi_ontology
def: "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." []
subset: 3_STAR
synonym: "group 15 elements" RELATED [ChEBI]
synonym: "group V elements" RELATED [ChEBI]
synonym: "nitrogenoideos" RELATED [ChEBI]
synonym: "nitrogenoides" RELATED [ChEBI]
synonym: "pnictogene" RELATED [ChEBI]
synonym: "pnictogenes" RELATED [ChEBI]
synonym: "pnictogens" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:33302
name: pnictogen molecular entity
namespace: chebi_ontology
def: "A p-block molecular entity containing any pnictogen." []
subset: 3_STAR
synonym: "pnictogen molecular entities" RELATED [ChEBI]
synonym: "pnictogen molecular entity" EXACT [ChEBI]
is_a: CHEBI:33675 ! p-block molecular entity
relationship: has_part CHEBI:33300 ! pnictogen

[Term]
id: CHEBI:33303
name: chalcogen
namespace: chebi_ontology
def: "Any p-block element belonging to the group 16 family of the periodic table." []
subset: 3_STAR
synonym: "anfigeno" RELATED [ChEBI]
synonym: "anfigenos" RELATED [ChEBI]
synonym: "calcogeno" RELATED [ChEBI]
synonym: "calcogenos" RELATED [ChEBI]
synonym: "chalcogen" EXACT IUPAC_NAME [IUPAC]
synonym: "chalcogene" RELATED [ChEBI]
synonym: "chalcogenes" RELATED [ChEBI]
synonym: "chalcogens" EXACT IUPAC_NAME [IUPAC]
synonym: "Chalkogen" RELATED [ChEBI]
synonym: "Chalkogene" RELATED [ChEBI]
synonym: "group 16 elements" RELATED [ChEBI]
synonym: "group VI elements" RELATED [ChEBI]
xref: PMID:17084588 {source="Europe PMC"}
is_a: CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:33304
name: chalcogen molecular entity
namespace: chebi_ontology
def: "Any p-block molecular entity containing a chalcogen." []
subset: 3_STAR
synonym: "chalcogen compounds" RELATED [ChEBI]
synonym: "chalcogen molecular entities" RELATED [ChEBI]
synonym: "chalcogen molecular entity" EXACT [ChEBI]
is_a: CHEBI:33675 ! p-block molecular entity
relationship: has_part CHEBI:33303 ! chalcogen

[Term]
id: CHEBI:33306
name: carbon group element atom
namespace: chebi_ontology
subset: 3_STAR
synonym: "carbon group element" RELATED [ChEBI]
synonym: "carbon group elements" RELATED [ChEBI]
synonym: "carbonoides" RELATED [ChEBI]
synonym: "cristallogene" RELATED [ChEBI]
synonym: "cristallogenes" RELATED [ChEBI]
synonym: "group 14 elements" EXACT IUPAC_NAME [IUPAC]
synonym: "group IV elements" RELATED [ChEBI]
is_a: CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:33308
name: carboxylic ester
namespace: chebi_ontology
alt_id: CHEBI:13204
alt_id: CHEBI:23028
alt_id: CHEBI:3408
def: "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." []
subset: 3_STAR
synonym: "a carboxylic ester" RELATED [UniProt]
synonym: "carboxylic acid esters" RELATED [ChEBI]
synonym: "Carboxylic ester" EXACT [KEGG_COMPOUND]
synonym: "carboxylic esters" EXACT IUPAC_NAME [IUPAC]
xref: KEGG:C02391
xref: Wikipedia:Ester
is_a: CHEBI:35701 ! ester
is_a: CHEBI:36586 ! carbonyl compound
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "44.010" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C(=O)O[*]" xsd:string

[Term]
id: CHEBI:33318
name: main group element atom
namespace: chebi_ontology
def: "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." []
subset: 3_STAR
synonym: "Hauptgruppenelement" RELATED [ChEBI]
synonym: "Hauptgruppenelemente" RELATED [ChEBI]
synonym: "main group element" RELATED [ChEBI]
synonym: "main group elements" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:33250 ! atom

[Term]
id: CHEBI:33402
name: sulfur oxoacid
namespace: chebi_ontology
subset: 3_STAR
synonym: "oxoacids of sulfur" RELATED [ChEBI]
synonym: "sulfur oxoacids" RELATED [ChEBI]
is_a: CHEBI:26835 ! sulfur molecular entity
is_a: CHEBI:33484 ! chalcogen oxoacid

[Term]
id: CHEBI:33408
name: pnictogen oxoacid
namespace: chebi_ontology
subset: 3_STAR
synonym: "pnictogen oxoacids" RELATED [ChEBI]
is_a: CHEBI:24833 ! oxoacid
is_a: CHEBI:33302 ! pnictogen molecular entity
relationship: has_role CHEBI:138103 ! inorganic acid

[Term]
id: CHEBI:33424
name: sulfur oxoacid derivative
namespace: chebi_ontology
subset: 3_STAR
synonym: "sulfur oxoacid derivative" EXACT [ChEBI]
synonym: "sulfur oxoacid derivatives" RELATED [ChEBI]
is_a: CHEBI:26835 ! sulfur molecular entity
is_a: CHEBI:33241 ! oxoacid derivative

[Term]
id: CHEBI:33457
name: phosphorus oxoacid
namespace: chebi_ontology
def: "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." []
subset: 3_STAR
synonym: "oxoacids of phosphorus" RELATED [ChEBI]
synonym: "Oxosaeure des Phosphors" RELATED [ChEBI]
synonym: "phosphorus oxoacid" EXACT [ChEBI]
synonym: "phosphorus oxoacids" RELATED [ChEBI]
is_a: CHEBI:33408 ! pnictogen oxoacid
is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives

[Term]
id: CHEBI:33459
name: pnictogen oxoanion
namespace: chebi_ontology
subset: 3_STAR
synonym: "pnictogen oxoanion" EXACT [ChEBI]
synonym: "pnictogen oxoanions" RELATED [ChEBI]
is_a: CHEBI:33302 ! pnictogen molecular entity
is_a: CHEBI:35406 ! oxoanion

[Term]
id: CHEBI:33461
name: phosphorus oxoanion
namespace: chebi_ontology
subset: 3_STAR
synonym: "oxoanions of phosphorus" RELATED [ChEBI]
synonym: "phosphorus oxoanion" EXACT [ChEBI]
synonym: "phosphorus oxoanions" RELATED [ChEBI]
is_a: CHEBI:24834 ! inorganic anion
is_a: CHEBI:26082 ! phosphorus molecular entity
is_a: CHEBI:33459 ! pnictogen oxoanion

[Term]
id: CHEBI:33482
name: sulfur oxoanion
namespace: chebi_ontology
subset: 3_STAR
synonym: "oxoanions of sulfur" RELATED [ChEBI]
synonym: "sulfur oxoanion" EXACT [ChEBI]
synonym: "sulfur oxoanions" RELATED [ChEBI]
is_a: CHEBI:26835 ! sulfur molecular entity
is_a: CHEBI:33485 ! chalcogen oxoanion

[Term]
id: CHEBI:33484
name: chalcogen oxoacid
namespace: chebi_ontology
subset: 3_STAR
synonym: "chalcogen oxoacid" EXACT [ChEBI]
synonym: "chalcogen oxoacids" RELATED [ChEBI]
is_a: CHEBI:24833 ! oxoacid
relationship: has_role CHEBI:138103 ! inorganic acid

[Term]
id: CHEBI:33485
name: chalcogen oxoanion
namespace: chebi_ontology
subset: 3_STAR
synonym: "chalcogen oxoanion" EXACT [ChEBI]
synonym: "chalcogen oxoanions" RELATED [ChEBI]
is_a: CHEBI:35406 ! oxoanion

[Term]
id: CHEBI:33504
name: alkali metal cation
namespace: chebi_ontology
subset: 3_STAR
synonym: "alkali metal cations" RELATED [ChEBI]
is_a: CHEBI:25213 ! metal cation

[Term]
id: CHEBI:33521
name: metal atom
namespace: chebi_ontology
alt_id: CHEBI:25217
alt_id: CHEBI:6788
def: "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." []
subset: 3_STAR
synonym: "elemental metal" RELATED [ChEBI]
synonym: "elemental metals" RELATED [ChEBI]
synonym: "metal element" RELATED [ChEBI]
synonym: "metal elements" RELATED [ChEBI]
synonym: "metals" RELATED [ChEBI]
xref: KEGG:C00050
xref: PMID:21784043 {source="Europe PMC"}
xref: Wikipedia:Metal
is_a: CHEBI:33250 ! atom

[Term]
id: CHEBI:33558
name: alpha-amino-acid anion
namespace: chebi_ontology
def: "An amino-acid anion obtained by deprotonation of any alpha-amino acid." []
subset: 3_STAR
synonym: "alpha-amino acid anions" RELATED [ChEBI]
synonym: "alpha-amino-acid anion" EXACT [ChEBI]
synonym: "alpha-amino-acid anions" RELATED [ChEBI]
is_a: CHEBI:37022 ! amino-acid anion
relationship: is_conjugate_base_of CHEBI:33704 ! alpha-amino acid

[Term]
id: CHEBI:33559
name: s-block element atom
namespace: chebi_ontology
subset: 3_STAR
synonym: "s-block element" RELATED [ChEBI]
synonym: "s-block elements" RELATED [ChEBI]
is_a: CHEBI:33250 ! atom

[Term]
id: CHEBI:33560
name: p-block element atom
namespace: chebi_ontology
def: "Any main group element atom belonging to the p-block of the periodic table." []
subset: 3_STAR
synonym: "p-block element" RELATED [ChEBI]
synonym: "p-block elements" RELATED [ChEBI]
is_a: CHEBI:33318 ! main group element atom

[Term]
id: CHEBI:33566
name: catechols
namespace: chebi_ontology
alt_id: CHEBI:134187
alt_id: CHEBI:13628
alt_id: CHEBI:18862
def: "Any compound containing an o-diphenol component." []
subset: 3_STAR
synonym: "1,2-benzenediols" RELATED [ChEBI]
synonym: "a catechol" RELATED [UniProt]
synonym: "benzene-1,2-diols" RELATED [ChEBI]
xref: KEGG:C15571
is_a: CHEBI:33570 ! benzenediols
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H2O2R4" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "106.079" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "106.00548" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC1=C(O)C(*)=C(*)C(*)=C1*" xsd:string

[Term]
id: CHEBI:33567
name: catecholamine
namespace: chebi_ontology
alt_id: CHEBI:23056
alt_id: CHEBI:3468
def: "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." []
subset: 3_STAR
synonym: "Catecholamine" EXACT [KEGG_COMPOUND]
synonym: "catecholamines" EXACT IUPAC_NAME [IUPAC]
synonym: "catecholamines" RELATED [ChEBI]
xref: KEGG:C02012
is_a: CHEBI:25375 ! monoamine molecular messenger
is_a: CHEBI:33566 ! catechols
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H9NO2R2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "151.163" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "151.06333" xsd:string

[Term]
id: CHEBI:33569
name: noradrenaline
namespace: chebi_ontology
def: "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted." []
subset: 3_STAR
synonym: "4-(2-amino-1-hydroxyethyl)benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC]
synonym: "noradrenalina" RELATED [ChEBI]
synonym: "norepinephrine" RELATED [ChEBI]
xref: Beilstein:2210994 {source="Beilstein"}
xref: CAS:138-65-8 {source="NIST Chemistry WebBook"}
xref: CAS:138-65-8 {source="ChemIDplus"}
xref: Gmelin:863925 {source="Gmelin"}
xref: LINCS:LSM-5181
is_a: CHEBI:33567 ! catecholamine
relationship: has_role CHEBI:76967 ! human xenobiotic metabolite
relationship: is_conjugate_base_of CHEBI:166902 ! noradrenaline(1+)
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17788" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCC(O)c1ccc(O)c(O)c1" xsd:string

[Term]
id: CHEBI:33570
name: benzenediols
namespace: chebi_ontology
alt_id: CHEBI:22705
alt_id: CHEBI:22711
subset: 3_STAR
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:33571
name: (S)-noradrenaline
namespace: chebi_ontology
def: "The S-enantiomer of noradrenaline." []
subset: 3_STAR
synonym: "4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC]
xref: Beilstein:2937999 {source="Beilstein"}
xref: LINCS:LSM-37072
xref: Reaxys:2937999 {source="Reaxys"}
is_a: CHEBI:33569 ! noradrenaline
relationship: is_enantiomer_of CHEBI:18357 ! (R)-noradrenaline
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m1/s1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-MRVPVSSYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17788" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC[C@@H](O)c1ccc(O)c(O)c1" xsd:string

[Term]
id: CHEBI:33575
name: carboxylic acid
namespace: chebi_ontology
alt_id: CHEBI:13428
alt_id: CHEBI:13627
alt_id: CHEBI:23027
def: "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." []
subset: 3_STAR
synonym: "acide carboxylique" RELATED [IUPAC]
synonym: "acides carboxyliques" RELATED [IUPAC]
synonym: "acido carboxilico" RELATED [IUPAC]
synonym: "acidos carboxilicos" RELATED [IUPAC]
synonym: "Carbonsaeure" RELATED [ChEBI]
synonym: "Carbonsaeuren" RELATED [ChEBI]
synonym: "carboxylic acid" EXACT IUPAC_NAME [IUPAC]
synonym: "carboxylic acids" EXACT IUPAC_NAME [IUPAC]
synonym: "Karbonsaeure" RELATED [ChEBI]
synonym: "RC(=O)OH" RELATED [IUPAC]
xref: PMID:17147560 {source="Europe PMC"}
xref: PMID:18433345 {source="Europe PMC"}
xref: Wikipedia:Carboxylic_acid
is_a: CHEBI:35605 ! carbon oxoacid
is_a: CHEBI:36586 ! carbonyl compound
is_a: CHEBI:64709 ! organic acid
relationship: has_part CHEBI:46883 ! carboxy group
relationship: is_conjugate_acid_of CHEBI:29067 ! carboxylic acid anion
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2R" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01740" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([*])=O" xsd:string

[Term]
id: CHEBI:33579
name: main group molecular entity
namespace: chebi_ontology
def: "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." []
subset: 3_STAR
synonym: "main group compounds" RELATED [ChEBI]
synonym: "main group molecular entities" RELATED [ChEBI]
is_a: CHEBI:23367 ! molecular entity
relationship: has_part CHEBI:33318 ! main group element atom

[Term]
id: CHEBI:33582
name: carbon group molecular entity
namespace: chebi_ontology
subset: 3_STAR
synonym: "carbon group molecular entities" RELATED [ChEBI]
synonym: "carbon group molecular entity" EXACT [ChEBI]
is_a: CHEBI:33675 ! p-block molecular entity
relationship: has_part CHEBI:33306 ! carbon group element atom

[Term]
id: CHEBI:33595
name: cyclic compound
namespace: chebi_ontology
def: "Any molecule that consists of a series of atoms joined together to form a ring." []
subset: 3_STAR
synonym: "cyclic compounds" RELATED [ChEBI]
xref: Wikipedia:Cyclic_compound
is_a: CHEBI:25367 ! molecule

[Term]
id: CHEBI:33608
name: hydrogen molecular entity
namespace: chebi_ontology
subset: 3_STAR
synonym: "hydrogen compounds" RELATED [ChEBI]
synonym: "hydrogen molecular entities" RELATED [ChEBI]
is_a: CHEBI:33674 ! s-block molecular entity
relationship: has_part CHEBI:49637 ! hydrogen atom

[Term]
id: CHEBI:33635
name: polycyclic compound
namespace: chebi_ontology
subset: 3_STAR
synonym: "polycyclic compounds" RELATED [ChEBI]
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:33636
name: bicyclic compound
namespace: chebi_ontology
def: "A molecule that features two fused rings." []
subset: 3_STAR
synonym: "bicyclic compounds" RELATED [ChEBI]
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:33655
name: aromatic compound
namespace: chebi_ontology
def: "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." []
subset: 3_STAR
synonym: "aromatic compounds" EXACT IUPAC_NAME [IUPAC]
synonym: "aromatic molecular entity" EXACT IUPAC_NAME [IUPAC]
synonym: "aromatics" RELATED [ChEBI]
synonym: "aromatische Verbindungen" RELATED [ChEBI]
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:33659
name: organic aromatic compound
namespace: chebi_ontology
subset: 3_STAR
synonym: "organic aromatic compounds" RELATED [ChEBI]
is_a: CHEBI:33655 ! aromatic compound
is_a: CHEBI:33832 ! organic cyclic compound

[Term]
id: CHEBI:33671
name: heteropolycyclic compound
namespace: chebi_ontology
def: "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." []
subset: 3_STAR
synonym: "heteropolycyclic compounds" EXACT IUPAC_NAME [IUPAC]
synonym: "polyheterocyclic compounds" RELATED [ChEBI]
is_a: CHEBI:33635 ! polycyclic compound
is_a: CHEBI:5686 ! heterocyclic compound

[Term]
id: CHEBI:33672
name: heterobicyclic compound
namespace: chebi_ontology
def: "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." []
subset: 3_STAR
synonym: "heterobicyclic compounds" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:33636 ! bicyclic compound
is_a: CHEBI:5686 ! heterocyclic compound

[Term]
id: CHEBI:33674
name: s-block molecular entity
namespace: chebi_ontology
def: "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." []
subset: 3_STAR
synonym: "s-block compounds" RELATED [ChEBI]
synonym: "s-block molecular entities" RELATED [ChEBI]
synonym: "s-block molecular entity" EXACT [ChEBI]
is_a: CHEBI:33579 ! main group molecular entity
relationship: has_part CHEBI:33559 ! s-block element atom

[Term]
id: CHEBI:33675
name: p-block molecular entity
namespace: chebi_ontology
def: "A main group molecular entity that contains one or more atoms of a p-block element." []
subset: 3_STAR
synonym: "p-block compounds" RELATED [ChEBI]
synonym: "p-block molecular entities" RELATED [ChEBI]
synonym: "p-block molecular entitiy" RELATED [ChEBI]
is_a: CHEBI:33579 ! main group molecular entity
relationship: has_part CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:33692
name: hydrides
namespace: chebi_ontology
def: "Hydrides are chemical compounds of hydrogen with other chemical elements." []
subset: 3_STAR
is_a: CHEBI:33608 ! hydrogen molecular entity
is_a: CHEBI:37577 ! heteroatomic molecular entity

[Term]
id: CHEBI:33693
name: oxygen hydride
namespace: chebi_ontology
subset: 3_STAR
synonym: "hydrides of oxygen" RELATED [ChEBI]
synonym: "oxygen hydride" EXACT [ChEBI]
synonym: "oxygen hydrides" RELATED [ChEBI]
is_a: CHEBI:36902 ! chalcogen hydride

[Term]
id: CHEBI:33694
name: biomacromolecule
namespace: chebi_ontology
def: "A macromolecule formed by a living organism." []
subset: 3_STAR
synonym: "biomacromolecules" RELATED [ChEBI]
synonym: "biopolymer" EXACT IUPAC_NAME [IUPAC]
synonym: "Biopolymere" RELATED [ChEBI]
synonym: "biopolymers" RELATED [ChEBI]
is_a: CHEBI:33839 ! macromolecule
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33695
name: information biomacromolecule
namespace: chebi_ontology
subset: 3_STAR
synonym: "genetically encoded biomacromolecules" RELATED [ChEBI]
synonym: "genetically encoded biopolymers" RELATED [ChEBI]
synonym: "information biomacromolecules" RELATED [ChEBI]
synonym: "information biopolymers" RELATED [ChEBI]
synonym: "information macromolecule" RELATED [ChEBI]
synonym: "information macromolecules" RELATED [ChEBI]
is_a: CHEBI:33694 ! biomacromolecule

[Term]
id: CHEBI:33696
name: nucleic acid
namespace: chebi_ontology
def: "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." []
subset: 3_STAR
synonym: "acide nucleique" RELATED [ChEBI]
synonym: "acides nucleiques" RELATED [ChEBI]
synonym: "acido nucleico" RELATED [ChEBI]
synonym: "acidos nucleicos" RELATED [ChEBI]
synonym: "NA" RELATED [ChEBI]
synonym: "nucleic acids" EXACT IUPAC_NAME [IUPAC]
synonym: "Nukleinsaeure" RELATED [ChEBI]
synonym: "Nukleinsaeuren" RELATED [ChEBI]
is_a: CHEBI:15986 ! polynucleotide
relationship: has_part CHEBI:33791 ! canonical nucleoside residue
relationship: has_part CHEBI:50297 ! canonical nucleotide residue

[Term]
id: CHEBI:33697
name: ribonucleic acid
namespace: chebi_ontology
def: "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." []
subset: 3_STAR
synonym: "pentosenucleic acids" RELATED [ChemIDplus]
synonym: "ribonucleic acid" EXACT [IUPAC]
synonym: "ribonucleic acids" EXACT IUPAC_NAME [IUPAC]
synonym: "ribonucleic acids" RELATED [ChEBI]
synonym: "Ribonukleinsaeure" RELATED [ChEBI]
synonym: "ribose nucleic acid" RELATED [ChEBI]
synonym: "RNA" RELATED [UniProt]
synonym: "RNA" RELATED [IUPAC]
synonym: "RNS" RELATED [ChEBI]
synonym: "yeast nucleic acid" RELATED [ChEBI]
xref: CAS:63231-63-0 {source="ChemIDplus"}
is_a: CHEBI:33696 ! nucleic acid
relationship: has_part CHEBI:33792 ! canonical ribonucleoside residue
relationship: has_part CHEBI:50299 ! canonical ribonucleotide residue

[Term]
id: CHEBI:33700
name: proteinogenic amino-acid residue
namespace: chebi_ontology
subset: 3_STAR
synonym: "canonical amino-acid residue" RELATED [ChEBI]
synonym: "canonical amino-acid residues" RELATED [ChEBI]
synonym: "common amino acid residues" RELATED [ChEBI]
synonym: "proteinogenic amino-acid residues" RELATED [ChEBI]
synonym: "standard amino acid residues" RELATED [ChEBI]
synonym: "standard amino-acid residues" RELATED [ChEBI]
is_a: CHEBI:33710 ! alpha-amino-acid residue

[Term]
id: CHEBI:33702
name: polyatomic cation
namespace: chebi_ontology
def: "A cation consisting of more than one atom." []
subset: 3_STAR
synonym: "polyatomic cations" RELATED [ChEBI]
is_a: CHEBI:36358 ! polyatomic ion
is_a: CHEBI:36916 ! cation

[Term]
id: CHEBI:33704
name: alpha-amino acid
namespace: chebi_ontology
alt_id: CHEBI:10208
alt_id: CHEBI:13779
alt_id: CHEBI:22442
alt_id: CHEBI:2642
def: "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." []
subset: 3_STAR
synonym: "alpha-amino acid" EXACT IUPAC_NAME [IUPAC]
synonym: "alpha-amino acids" RELATED [JCBN]
synonym: "alpha-amino acids" RELATED [ChEBI]
synonym: "alpha-amino carboxylic acids" RELATED [IUPAC]
synonym: "Amino acid" RELATED [KEGG_COMPOUND]
synonym: "Amino acids" RELATED [KEGG_COMPOUND]
xref: KEGG:C00045
xref: KEGG:C05167
is_a: CHEBI:33709 ! amino acid
relationship: is_conjugate_acid_of CHEBI:33558 ! alpha-amino-acid anion
relationship: is_tautomer_of CHEBI:78608 ! alpha-amino acid zwitterion
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "74.05870" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC([*])C(O)=O" xsd:string

[Term]
id: CHEBI:33708
name: amino-acid residue
namespace: chebi_ontology
def: "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." [Dummy:dummy]
subset: 3_STAR
synonym: "amino acid residue" EXACT []
synonym: "amino acid residue" RELATED [ChEBI]
synonym: "amino-acid residue" EXACT IUPAC_NAME [IUPAC]
synonym: "amino-acid residues" RELATED [JCBN]
synonym: "protein residue" NARROW [PRO:DAN]
is_a: CHEBI:33247 ! organic group
relationship: is_substituent_group_from CHEBI:33709 ! amino acid

[Term]
id: CHEBI:33709
name: amino acid
namespace: chebi_ontology
alt_id: CHEBI:13815
alt_id: CHEBI:22477
def: "A carboxylic acid containing one or more amino groups." []
subset: 3_STAR
synonym: "amino acids" RELATED [ChEBI]
synonym: "Aminocarbonsaeure" RELATED [ChEBI]
synonym: "Aminokarbonsaeure" RELATED [ChEBI]
synonym: "Aminosaeure" RELATED [ChEBI]
xref: Wikipedia:Amino_acid
is_a: CHEBI:33575 ! carboxylic acid
is_a: CHEBI:50047 ! organic amino compound
relationship: is_conjugate_acid_of CHEBI:37022 ! amino-acid anion

[Term]
id: CHEBI:33710
name: alpha-amino-acid residue
namespace: chebi_ontology
subset: 3_STAR
synonym: "alpha-amino-acid residues" RELATED [ChEBI]
is_a: CHEBI:33708 ! amino-acid residue
relationship: is_substituent_group_from CHEBI:33704 ! alpha-amino acid

[Term]
id: CHEBI:33720
name: carbohydrate acid
namespace: chebi_ontology
subset: 3_STAR
synonym: "carbohydrate acid" EXACT [ChEBI]
synonym: "carbohydrate acids" RELATED [ChEBI]
is_a: CHEBI:16646 ! carbohydrate
is_a: CHEBI:33575 ! carboxylic acid
relationship: is_conjugate_acid_of CHEBI:33721 ! carbohydrate acid anion

[Term]
id: CHEBI:33721
name: carbohydrate acid anion
namespace: chebi_ontology
subset: 3_STAR
synonym: "carbohydrate acid anion" EXACT [ChEBI]
synonym: "carbohydrate acid anions" RELATED [ChEBI]
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: is_conjugate_base_of CHEBI:33720 ! carbohydrate acid

[Term]
id: CHEBI:33791
name: canonical nucleoside residue
namespace: chebi_ontology
subset: 3_STAR
synonym: "canonical nucleoside residues" RELATED [ChEBI]
synonym: "common nucleoside residues" RELATED [CBN]
synonym: "nucleoside residue" RELATED [CBN]
synonym: "standard nucleoside residues" RELATED [ChEBI]
is_a: CHEBI:50320 ! nucleoside residue

[Term]
id: CHEBI:33792
name: canonical ribonucleoside residue
namespace: chebi_ontology
subset: 3_STAR
synonym: "canonical ribonucleoside residues" RELATED [ChEBI]
synonym: "common ribonucleoside residue" RELATED [CBN]
synonym: "common ribonucleoside residues" RELATED [CBN]
synonym: "N" RELATED [CBN]
synonym: "Nuc" RELATED [CBN]
synonym: "standard ribonucleoside residues" RELATED [ChEBI]
is_a: CHEBI:33791 ! canonical nucleoside residue

[Term]
id: CHEBI:33793
name: canonical deoxyribonucleoside residue
namespace: chebi_ontology
subset: 3_STAR
synonym: "canonical deoxyribonucleoside residues" RELATED [ChEBI]
synonym: "common 2'-deoxyribonucleoside residue" RELATED [CBN]
synonym: "common 2'-deoxyribonucleoside residues" RELATED [CBN]
synonym: "dN" RELATED [CBN]
synonym: "dNuc" RELATED [CBN]
synonym: "standard deoxyribonucleoside residues" RELATED [ChEBI]
is_a: CHEBI:33791 ! canonical nucleoside residue

[Term]
id: CHEBI:33822
name: organic hydroxy compound
namespace: chebi_ontology
alt_id: CHEBI:64710
def: "An organic compound having at least one hydroxy group attached to a carbon atom." []
subset: 3_STAR
synonym: "hydroxy compounds" EXACT IUPAC_NAME [IUPAC]
synonym: "organic alcohol" RELATED [ChEBI]
synonym: "organic hydroxy compounds" RELATED [ChEBI]
is_a: CHEBI:24651 ! hydroxides
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33832
name: organic cyclic compound
namespace: chebi_ontology
def: "Any organic molecule that consists of atoms connected in the form of a ring." []
subset: 3_STAR
synonym: "organic cyclic compounds" RELATED [ChEBI]
is_a: CHEBI:33595 ! cyclic compound
is_a: CHEBI:72695 ! organic molecule

[Term]
id: CHEBI:33833
name: heteroarene
namespace: chebi_ontology
def: "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." []
subset: 3_STAR
synonym: "hetarenes" RELATED [IUPAC]
synonym: "heteroarenes" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:24532 ! organic heterocyclic compound
is_a: CHEBI:33659 ! organic aromatic compound

[Term]
id: CHEBI:33837
name: conjugated protein
namespace: chebi_ontology
def: "Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion." []
subset: 3_STAR
synonym: "complex protein" RELATED [COMe]
synonym: "conjugated proteins" EXACT IUPAC_NAME [IUPAC]
xref: COMe:PRX000001
is_a: CHEBI:36080 ! protein

[Term]
id: CHEBI:33839
name: macromolecule
namespace: chebi_ontology
def: "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." []
subset: 3_STAR
synonym: "macromolecule" EXACT IUPAC_NAME [IUPAC]
synonym: "macromolecules" RELATED [ChEBI]
synonym: "polymer" RELATED [ChEBI]
synonym: "polymer molecule" RELATED [IUPAC]
synonym: "polymers" RELATED [ChEBI]
xref: Wikipedia:Macromolecule
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:33853
name: phenols
namespace: chebi_ontology
alt_id: CHEBI:13664
alt_id: CHEBI:13825
alt_id: CHEBI:25969
alt_id: CHEBI:2857
def: "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." []
subset: 3_STAR
synonym: "a phenol" RELATED [UniProt]
synonym: "arenols" RELATED [IUPAC]
synonym: "Aryl alcohol" RELATED [KEGG_COMPOUND]
synonym: "phenols" EXACT IUPAC_NAME [IUPAC]
xref: KEGG:C15584
xref: MetaCyc:Phenols
xref: Wikipedia:Phenols
is_a: CHEBI:33659 ! organic aromatic compound
is_a: CHEBI:33822 ! organic hydroxy compound
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C6HOR5" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "89.072" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "89.00274" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(=C(C(=C(C(=C1*)*)*)*)*)O" xsd:string

[Term]
id: CHEBI:33893
name: reagent
namespace: chebi_ontology
def: "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." []
subset: 3_STAR
synonym: "reactif" RELATED [IUPAC]
synonym: "reactivo" RELATED [IUPAC]
synonym: "reagent" EXACT IUPAC_NAME [IUPAC]
synonym: "reagents" RELATED [ChEBI]
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:33917
name: aldohexose
namespace: chebi_ontology
alt_id: CHEBI:2558
def: "A hexose with a (potential) aldehyde group at one end." []
subset: 3_STAR
synonym: "aldohexose" EXACT [ChEBI]
synonym: "aldohexoses" RELATED [ChEBI]
is_a: CHEBI:15693 ! aldose
is_a: CHEBI:18133 ! hexose

[Term]
id: CHEBI:33937
name: macronutrient
namespace: chebi_ontology
def: "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." []
subset: 3_STAR
synonym: "macronutrients" RELATED [ChEBI]
is_a: CHEBI:33284 ! nutrient

[Term]
id: CHEBI:350546
name: serotonin(1+)
namespace: chebi_ontology
def: "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." []
subset: 3_STAR
synonym: "2-(5-hydroxy-1H-indol-3-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC]
synonym: "serotonin" RELATED [UniProt]
synonym: "serotonin cation" RELATED [ChEBI]
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_acid_of CHEBI:28790 ! serotonin
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H13N2O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "177.22250" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "177.10224" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCc1c[nH]c2ccc(O)cc12" xsd:string

[Term]
id: CHEBI:35106
name: nitrogen hydride
namespace: chebi_ontology
subset: 3_STAR
synonym: "nitrogen hydrides" RELATED [ChEBI]
is_a: CHEBI:35881 ! pnictogen hydride
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:35107
name: azane
namespace: chebi_ontology
def: "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." []
subset: 3_STAR
synonym: "azanes" RELATED [ChEBI]
is_a: CHEBI:35106 ! nitrogen hydride

[Term]
id: CHEBI:35222
name: inhibitor
namespace: chebi_ontology
def: "A substance that diminishes the rate of a chemical reaction." []
subset: 3_STAR
synonym: "inhibidor" RELATED [ChEBI]
synonym: "inhibiteur" RELATED [ChEBI]
synonym: "inhibitor" EXACT IUPAC_NAME [IUPAC]
synonym: "inhibitors" RELATED [ChEBI]
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:35223
name: catalyst
namespace: chebi_ontology
def: "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." []
subset: 3_STAR
synonym: "catalizador" RELATED [ChEBI]
synonym: "catalyseur" RELATED [ChEBI]
synonym: "catalyst" EXACT IUPAC_NAME [IUPAC]
synonym: "Katalysator" RELATED [ChEBI]
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:35238
name: amino acid zwitterion
namespace: chebi_ontology
def: "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." []
subset: 3_STAR
synonym: "amino acid zwitterion" EXACT [ChEBI]
is_a: CHEBI:27369 ! zwitterion

[Term]
id: CHEBI:35267
name: quaternary ammonium ion
namespace: chebi_ontology
alt_id: CHEBI:26470
alt_id: CHEBI:8693
def: "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." []
subset: 3_STAR
synonym: "a quaternary ammonium" RELATED [UniProt]
synonym: "Quaternary amine" RELATED [KEGG_COMPOUND]
synonym: "quaternary ammonium ion" EXACT IUPAC_NAME [IUPAC]
synonym: "quaternary ammonium ions" RELATED [ChEBI]
xref: KEGG:C06703
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "NR4" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "14.00670" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "14.00307" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*][N+]([*])([*])[*]" xsd:string

[Term]
id: CHEBI:35274
name: ammonium ion derivative
namespace: chebi_ontology
def: "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." []
subset: 3_STAR
synonym: "ammonium ion derivatives" RELATED [ChEBI]
synonym: "azanium ion derivative" RELATED [ChEBI]
synonym: "azanium ion derivatives" RELATED [ChEBI]
is_a: CHEBI:33702 ! polyatomic cation
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: has_parent_hydride CHEBI:28938 ! ammonium

[Term]
id: CHEBI:35287
name: acylcholine
namespace: chebi_ontology
alt_id: CHEBI:13245
alt_id: CHEBI:22227
alt_id: CHEBI:2463
def: "A choline ester formed from choline and a carboxylic acid." []
subset: 3_STAR
synonym: "acylcholines" RELATED [ChEBI]
synonym: "an acylcholine" RELATED [UniProt]
xref: KEGG:C01777
is_a: CHEBI:35267 ! quaternary ammonium ion
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H13NO2R" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "131.17290" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "131.09463" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "C[N+](C)(C)CCOC([*])=O" xsd:string

[Term]
id: CHEBI:35341
name: steroid
namespace: chebi_ontology
alt_id: CHEBI:13687
alt_id: CHEBI:26768
alt_id: CHEBI:9263
def: "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." []
subset: 3_STAR
synonym: "a steroid" RELATED [UniProt]
synonym: "Steroid" EXACT [KEGG_COMPOUND]
synonym: "steroids" EXACT IUPAC_NAME [IUPAC]
xref: KEGG:C00377
xref: MetaCyc:Steroids
is_a: CHEBI:18059 ! lipid
is_a: CHEBI:51958 ! organic polycyclic compound
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H31R" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "259.450" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "259.24258" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C" xsd:string

[Term]
id: CHEBI:35350
name: hydroxy steroid
namespace: chebi_ontology
alt_id: CHEBI:24748
alt_id: CHEBI:5814
subset: 3_STAR
synonym: "hydroxy steroids" RELATED [ChEBI]
synonym: "Hydroxysteroid" RELATED [KEGG_COMPOUND]
synonym: "hydroxysteroids" RELATED [ChEBI]
xref: KEGG:C02159
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:35352
name: organonitrogen compound
namespace: chebi_ontology
def: "Any heteroorganic entity containing at least one carbon-nitrogen bond." []
subset: 3_STAR
synonym: "organonitrogen compounds" EXACT IUPAC_NAME [IUPAC]
synonym: "organonitrogens" RELATED [ChEBI]
is_a: CHEBI:33285 ! heteroorganic entity
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:35381
name: monosaccharide
namespace: chebi_ontology
alt_id: CHEBI:25407
alt_id: CHEBI:6984
def: "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." []
subset: 3_STAR
synonym: "monosacarido" RELATED [ChEBI]
synonym: "monosacaridos" RELATED [IUPAC]
synonym: "Monosaccharid" RELATED [ChEBI]
synonym: "Monosaccharide" EXACT [KEGG_COMPOUND]
synonym: "monosaccharides" EXACT IUPAC_NAME [IUPAC]
synonym: "Monosacharid" RELATED [ChEBI]
xref: KEGG:C06698
is_a: CHEBI:16646 ! carbohydrate

[Term]
id: CHEBI:35406
name: oxoanion
namespace: chebi_ontology
alt_id: CHEBI:33274
alt_id: CHEBI:33436
def: "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." []
subset: 3_STAR
synonym: "oxoacid anions" RELATED [ChEBI]
synonym: "oxoanion" EXACT [ChEBI]
synonym: "oxoanions" RELATED [ChEBI]
is_a: CHEBI:25741 ! oxide
is_a: CHEBI:33273 ! polyatomic anion

[Term]
id: CHEBI:35472
name: anti-inflammatory drug
namespace: chebi_ontology
def: "A substance that reduces or suppresses inflammation." []
subset: 3_STAR
synonym: "anti-inflammatory drugs" RELATED [ChEBI]
synonym: "antiinflammatory agent" RELATED [ChEBI]
synonym: "antiinflammatory drug" RELATED [ChEBI]
synonym: "antiinflammatory drugs" RELATED [ChEBI]
is_a: CHEBI:23888 ! drug
is_a: CHEBI:67079 ! anti-inflammatory agent

[Term]
id: CHEBI:35479
name: alkali metal salt
namespace: chebi_ontology
subset: 3_STAR
synonym: "alkali metal salts" RELATED [ChEBI]
is_a: CHEBI:24866 ! salt
is_a: CHEBI:33296 ! alkali metal molecular entity

[Term]
id: CHEBI:35507
name: natural product fundamental parent
namespace: chebi_ontology
subset: 3_STAR
synonym: "natural product fundamental parents" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:33245 ! organic fundamental parent

[Term]
id: CHEBI:35508
name: steroid fundamental parent
namespace: chebi_ontology
subset: 3_STAR
synonym: "steroid fundamental parents" RELATED [ChEBI]
is_a: CHEBI:35341 ! steroid
is_a: CHEBI:35507 ! natural product fundamental parent

[Term]
id: CHEBI:35519
name: cholane
namespace: chebi_ontology
subset: 3_STAR
synonym: "cholane" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:35508 ! steroid fundamental parent
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H42" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18?,19+,20-,21+,22+,23+,24-/m1/s1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QSHQKIURKJITMZ-BRPMRXRMSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "330.59028" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "330.32865" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC" xsd:string

[Term]
id: CHEBI:35524
name: sympathomimetic agent
namespace: chebi_ontology
def: "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." []
subset: 3_STAR
synonym: "sympathomimetic" RELATED [ChEBI]
synonym: "sympathomimetics" RELATED [ChEBI]
is_a: CHEBI:37962 ! adrenergic agent

[Term]
id: CHEBI:35554
name: cardiovascular drug
namespace: chebi_ontology
def: "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." []
subset: 3_STAR
synonym: "cardiovascular agent" RELATED [ChEBI]
synonym: "cardiovascular drugs" RELATED [ChEBI]
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35569
name: alpha-adrenergic agonist
namespace: chebi_ontology
def: "An agent that selectively binds to and activates alpha-adrenergic receptors." []
subset: 3_STAR
synonym: "alpha-adrenergic agonists" RELATED [ChEBI]
synonym: "alpha-adrenergic receptor agonist" RELATED [ChEBI]
synonym: "alpha-adrenoceptor agonists" RELATED [IUPHAR]
is_a: CHEBI:37886 ! adrenergic agonist
is_a: CHEBI:48539 ! alpha-adrenergic drug

[Term]
id: CHEBI:35604
name: carbon oxoanion
namespace: chebi_ontology
def: "A negative ion consisting solely of carbon and oxygen  atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." []
subset: 3_STAR
synonym: "carbon oxoanion" EXACT [ChEBI]
synonym: "carbon oxoanions" RELATED [ChEBI]
synonym: "oxocarbon anion" RELATED [ChEBI]
synonym: "oxocarbon anions" RELATED [ChEBI]
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:35406 ! oxoanion
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:35605
name: carbon oxoacid
namespace: chebi_ontology
subset: 3_STAR
synonym: "carbon oxoacids" RELATED [ChEBI]
synonym: "oxoacids of carbon" RELATED [ChEBI]
is_a: CHEBI:24833 ! oxoacid
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:35620
name: vasodilator agent
namespace: chebi_ontology
def: "A drug used to cause dilation of the blood vessels." []
subset: 3_STAR
synonym: "vasodilator" RELATED [ChEBI]
synonym: "vasodilator agents" RELATED [ChEBI]
is_a: CHEBI:35554 ! cardiovascular drug

[Term]
id: CHEBI:35692
name: dicarboxylic acid
namespace: chebi_ontology
alt_id: CHEBI:23692
alt_id: CHEBI:36172
alt_id: CHEBI:4501
def: "Any carboxylic acid containing two carboxy groups." []
subset: 3_STAR
synonym: "Dicarboxylic acid" EXACT [KEGG_COMPOUND]
synonym: "dicarboxylic acids" RELATED [ChEBI]
xref: KEGG:C02028
is_a: CHEBI:131927 ! dicarboxylic acids and O-substituted derivatives
is_a: CHEBI:33575 ! carboxylic acid
relationship: is_conjugate_acid_of CHEBI:35693 ! dicarboxylic acid anion

[Term]
id: CHEBI:35693
name: dicarboxylic acid anion
namespace: chebi_ontology
subset: 3_STAR
synonym: "dicarboxylic acid anion" EXACT [ChEBI]
synonym: "dicarboxylic acid anions" RELATED [ChEBI]
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: is_conjugate_base_of CHEBI:35692 ! dicarboxylic acid

[Term]
id: CHEBI:35701
name: ester
namespace: chebi_ontology
alt_id: CHEBI:23960
alt_id: CHEBI:4859
def: "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." []
subset: 3_STAR
synonym: "Ester" EXACT [KEGG_COMPOUND]
synonym: "esters" RELATED [ChEBI]
xref: KEGG:C00287
xref: Wikipedia:Ester
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:35722
name: sulfated glycosaminoglycan
namespace: chebi_ontology
subset: 3_STAR
synonym: "glycosaminoglycan sulfate" RELATED [ChEBI]
synonym: "glycosaminoglycan sulfates" RELATED [ChEBI]
synonym: "sulfated glycosaminoglycans" RELATED [ChEBI]
is_a: CHEBI:18085 ! glycosaminoglycan
is_a: CHEBI:35724 ! carbohydrate sulfate

[Term]
id: CHEBI:35724
name: carbohydrate sulfate
namespace: chebi_ontology
subset: 3_STAR
synonym: "carbohydrate sulfates" RELATED [ChEBI]
synonym: "carbohydrate sulphates" RELATED [ChEBI]
is_a: CHEBI:25704 ! organic sulfate
is_a: CHEBI:26819 ! sulfuric ester
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:35757
name: monocarboxylic acid anion
namespace: chebi_ontology
alt_id: CHEBI:13657
alt_id: CHEBI:25382
alt_id: CHEBI:3407
def: "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." []
subset: 3_STAR
synonym: "a monocarboxylate" RELATED [UniProt]
synonym: "Carboxylate" RELATED [KEGG_COMPOUND]
synonym: "Monocarboxylate" RELATED [KEGG_COMPOUND]
synonym: "monocarboxylates" RELATED [ChEBI]
synonym: "monocarboxylic acid anions" RELATED [ChEBI]
xref: KEGG:C00060
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: is_conjugate_base_of CHEBI:25384 ! monocarboxylic acid
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "44.01000" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string

[Term]
id: CHEBI:35780
name: phosphate ion
namespace: chebi_ontology
def: "A phosphorus oxoanion that is the conjugate base of phosphoric acid." []
subset: 3_STAR
synonym: "phosphate" RELATED [ChEBI]
synonym: "phosphate ions" RELATED [ChEBI]
synonym: "Pi" RELATED [ChEBI]
is_a: CHEBI:33461 ! phosphorus oxoanion
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_base_of CHEBI:26078 ! phosphoric acid

[Term]
id: CHEBI:35881
name: pnictogen hydride
namespace: chebi_ontology
subset: 3_STAR
synonym: "pnictogen hydride" EXACT [ChEBI]
synonym: "pnictogen hydrides" RELATED [ChEBI]
is_a: CHEBI:33242 ! inorganic hydride
is_a: CHEBI:33302 ! pnictogen molecular entity

[Term]
id: CHEBI:35942
name: neurotransmitter agent
namespace: chebi_ontology
def: "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." []
subset: 3_STAR
synonym: "neurotransmitter agents" RELATED [ChEBI]
is_a: CHEBI:23888 ! drug
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:36078
name: cholanoid
namespace: chebi_ontology
alt_id: CHEBI:22867
alt_id: CHEBI:50419
subset: 3_STAR
synonym: "bile acids and derivatives" RELATED [LIPID_MAPS]
synonym: "cholanoids" RELATED [ChEBI]
xref: LIPID_MAPS_class:LMST04 {source="LIPID MAPS"}
is_a: CHEBI:35341 ! steroid
relationship: has_parent_hydride CHEBI:35519 ! cholane

[Term]
id: CHEBI:36080
name: protein
namespace: chebi_ontology
alt_id: CHEBI:13677
alt_id: CHEBI:14911
def: "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." []
subset: 3_STAR
synonym: "proteins" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:33695 ! information biomacromolecule
relationship: has_part CHEBI:16541 ! protein polypeptide chain

[Term]
id: CHEBI:36235
name: bile acid anion
namespace: chebi_ontology
subset: 3_STAR
synonym: "bile acid anions" RELATED [ChEBI]
is_a: CHEBI:35757 ! monocarboxylic acid anion
is_a: CHEBI:50160 ! steroid acid anion

[Term]
id: CHEBI:36237
name: cholanic acid
namespace: chebi_ontology
def: "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24." []
subset: 3_STAR
synonym: "cholan-24-oic acid" EXACT IUPAC_NAME [IUPAC]
xref: CAS:25312-65-6 {source="ChemIDplus"}
xref: Patent:JP2008069152
xref: Reaxys:13246008 {source="Reaxys"}
is_a: CHEBI:36278 ! cholanic acids
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H40O2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17?,18+,19-,20+,21+,23+,24-/m1/s1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RPKLZQLYODPWTM-KBMWBBLPSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "360.57320" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "360.30283" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O" xsd:string

[Term]
id: CHEBI:36238
name: 5beta-cholanic acid
namespace: chebi_ontology
subset: 3_STAR
synonym: "(5beta)-cholan-24-oic acid" RELATED [ChemIDplus]
synonym: "(5beta,17beta)-gamma-methylandrostane-17-butanoic acid" RELATED [ChemIDplus]
synonym: "5beta-cholan-24-oic acid" EXACT IUPAC_NAME [IUPAC]
synonym: "5beta-cholanic acid" EXACT [ChemIDplus]
synonym: "5beta-cholanoic acid" RELATED [ChemIDplus]
synonym: "ursocholanic acid" RELATED [ChemIDplus]
xref: Beilstein:3214794 {source="Beilstein"}
xref: CAS:546-18-9 {source="ChemIDplus"}
xref: LIPID_MAPS_instance:LMST04010441 {source="LIPID MAPS"}
is_a: CHEBI:36237 ! cholanic acid
is_a: CHEBI:36248 ! 5beta-cholanic acids
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H40O2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17+,18+,19-,20+,21+,23+,24-/m1/s1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RPKLZQLYODPWTM-LVVAJZGHSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "360.57320" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "360.30283" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC(O)=O" xsd:string

[Term]
id: CHEBI:36248
name: 5beta-cholanic acids
namespace: chebi_ontology
def: "Members of the class of cholanic acids based on a 5beta-cholane skeleton." []
subset: 3_STAR
is_a: CHEBI:136889 ! 5beta steroid
is_a: CHEBI:36278 ! cholanic acids
relationship: has_parent_hydride CHEBI:20664 ! 5beta-cholane

[Term]
id: CHEBI:36277
name: bile acid salt
namespace: chebi_ontology
def: "A salt of a bile acid." []
subset: 3_STAR
synonym: "bile acid salts" RELATED [ChEBI]
is_a: CHEBI:24868 ! organic salt
is_a: CHEBI:36078 ! cholanoid

[Term]
id: CHEBI:36278
name: cholanic acids
namespace: chebi_ontology
alt_id: CHEBI:23166
alt_id: CHEBI:23211
subset: 1_STAR
is_a: CHEBI:36078 ! cholanoid
is_a: CHEBI:47891 ! steroid acid

[Term]
id: CHEBI:36338
name: lepton
namespace: chebi_ontology
def: "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." []
subset: 3_STAR
synonym: "leptons" RELATED [ChEBI]
is_a: CHEBI:33233 ! fundamental particle
is_a: CHEBI:36340 ! fermion

[Term]
id: CHEBI:36339
name: baryon
namespace: chebi_ontology
def: "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." []
subset: 3_STAR
synonym: "baryons" RELATED [ChEBI]
is_a: CHEBI:36340 ! fermion
is_a: CHEBI:36344 ! hadron

[Term]
id: CHEBI:36340
name: fermion
namespace: chebi_ontology
def: "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." []
subset: 3_STAR
synonym: "fermion" EXACT IUPAC_NAME [IUPAC]
synonym: "fermions" RELATED [ChEBI]
is_a: CHEBI:36342 ! subatomic particle

[Term]
id: CHEBI:36341
name: boson
namespace: chebi_ontology
def: "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose." []
subset: 3_STAR
synonym: "boson" EXACT IUPAC_NAME [IUPAC]
synonym: "bosons" RELATED [ChEBI]
is_a: CHEBI:36342 ! subatomic particle

[Term]
id: CHEBI:36342
name: subatomic particle
namespace: chebi_ontology
def: "A particle smaller than an atom." []
subset: 3_STAR
synonym: "subatomic particles" RELATED [ChEBI]
xref: Wikipedia:Subatomic_particle

[Term]
id: CHEBI:36343
name: composite particle
namespace: chebi_ontology
def: "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." []
subset: 3_STAR
synonym: "composite particles" RELATED [ChEBI]
is_a: CHEBI:36342 ! subatomic particle

[Term]
id: CHEBI:36344
name: hadron
namespace: chebi_ontology
def: "Hadron is a subatomic particle which experiences the strong force." []
subset: 3_STAR
synonym: "hadrons" RELATED [ChEBI]
is_a: CHEBI:36343 ! composite particle

[Term]
id: CHEBI:36347
name: nuclear particle
namespace: chebi_ontology
def: "A nucleus or any of its constituents in any of their energy states." []
subset: 3_STAR
synonym: "nuclear particle" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:36342 ! subatomic particle

[Term]
id: CHEBI:36357
name: polyatomic entity
namespace: chebi_ontology
def: "Any molecular entity consisting of more than one atom." []
subset: 3_STAR
synonym: "polyatomic entities" RELATED [ChEBI]
is_a: CHEBI:23367 ! molecular entity
relationship: has_part CHEBI:24433 ! group

[Term]
id: CHEBI:36358
name: polyatomic ion
namespace: chebi_ontology
def: "An ion consisting of more than one atom." []
subset: 3_STAR
synonym: "polyatomic ions" RELATED [ChEBI]
is_a: CHEBI:24870 ! ion
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:36359
name: phosphorus oxoacid derivative
namespace: chebi_ontology
subset: 3_STAR
synonym: "phosphorus oxoacid derivative" EXACT [ChEBI]
is_a: CHEBI:33241 ! oxoacid derivative
is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives
relationship: has_functional_parent CHEBI:33457 ! phosphorus oxoacid

[Term]
id: CHEBI:36360
name: phosphorus oxoacids and derivatives
namespace: chebi_ontology
subset: 1_STAR
is_a: CHEBI:26082 ! phosphorus molecular entity

[Term]
id: CHEBI:36586
name: carbonyl compound
namespace: chebi_ontology
def: "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." []
subset: 3_STAR
synonym: "carbonyl compounds" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:36587 ! organic oxo compound
is_a: CHEBI:36963 ! organooxygen compound
relationship: has_part CHEBI:23019 ! carbonyl group

[Term]
id: CHEBI:36587
name: organic oxo compound
namespace: chebi_ontology
def: "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." []
subset: 3_STAR
synonym: "organic oxo compounds" RELATED [ChEBI]
synonym: "oxo compounds" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:72695 ! organic molecule
relationship: has_part CHEBI:46629 ! oxo group

[Term]
id: CHEBI:36735
name: biladienes
namespace: chebi_ontology
def: "Compounds based on a biladiene skeleton." []
subset: 3_STAR
is_a: CHEBI:25046 ! linear tetrapyrrole

[Term]
id: CHEBI:36902
name: chalcogen hydride
namespace: chebi_ontology
subset: 3_STAR
synonym: "chalcogen hydride" EXACT [ChEBI]
synonym: "chalcogen hydrides" RELATED [ChEBI]
is_a: CHEBI:33242 ! inorganic hydride
is_a: CHEBI:33304 ! chalcogen molecular entity

[Term]
id: CHEBI:36914
name: inorganic ion
namespace: chebi_ontology
subset: 3_STAR
synonym: "inorganic ions" RELATED [ChEBI]
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:24870 ! ion

[Term]
id: CHEBI:36915
name: inorganic cation
namespace: chebi_ontology
subset: 3_STAR
synonym: "inorganic cations" RELATED [ChEBI]
is_a: CHEBI:36914 ! inorganic ion
is_a: CHEBI:36916 ! cation

[Term]
id: CHEBI:36916
name: cation
namespace: chebi_ontology
alt_id: CHEBI:23058
alt_id: CHEBI:3473
def: "A monoatomic or polyatomic species having one or more elementary charges of the proton." []
subset: 3_STAR
synonym: "Cation" EXACT [KEGG_COMPOUND]
synonym: "cation" EXACT IUPAC_NAME [IUPAC]
synonym: "cation" EXACT [ChEBI]
synonym: "cationes" RELATED [ChEBI]
synonym: "cations" RELATED [ChEBI]
synonym: "Kation" RELATED [ChEBI]
synonym: "Kationen" RELATED [ChEBI]
xref: KEGG:C01373
is_a: CHEBI:24870 ! ion

[Term]
id: CHEBI:36961
name: chalcocarbonic acid
namespace: chebi_ontology
subset: 3_STAR
synonym: "chalcocarbonic acid" EXACT [ChEBI]
synonym: "chalcocarbonic acids" EXACT IUPAC_NAME [IUPAC]
synonym: "chalcocarbonic acids" RELATED [ChEBI]
is_a: CHEBI:36962 ! organochalcogen compound

[Term]
id: CHEBI:36962
name: organochalcogen compound
namespace: chebi_ontology
def: "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." []
subset: 3_STAR
synonym: "organochalcogen compound" EXACT [ChEBI]
synonym: "organochalcogen compounds" RELATED [ChEBI]
is_a: CHEBI:33285 ! heteroorganic entity
is_a: CHEBI:33304 ! chalcogen molecular entity

[Term]
id: CHEBI:36963
name: organooxygen compound
namespace: chebi_ontology
def: "An organochalcogen compound containing at least one carbon-oxygen bond." []
subset: 3_STAR
synonym: "organooxygen compound" EXACT [ChEBI]
synonym: "organooxygen compounds" RELATED [ChEBI]
xref: PMID:17586126 {source="Europe PMC"}
is_a: CHEBI:25806 ! oxygen molecular entity
is_a: CHEBI:36962 ! organochalcogen compound

[Term]
id: CHEBI:37022
name: amino-acid anion
namespace: chebi_ontology
subset: 3_STAR
synonym: "amino acid anions" RELATED [ChEBI]
synonym: "amino-acid anion" EXACT [ChEBI]
synonym: "amino-acid anions" RELATED [ChEBI]
is_a: CHEBI:29067 ! carboxylic acid anion
is_a: CHEBI:35352 ! organonitrogen compound
relationship: is_conjugate_base_of CHEBI:33709 ! amino acid

[Term]
id: CHEBI:37163
name: glucan
namespace: chebi_ontology
alt_id: CHEBI:24255
alt_id: CHEBI:5392
def: "A polysaccharide composed of glucose residues." []
subset: 3_STAR
synonym: "Glucan" EXACT [KEGG_COMPOUND]
synonym: "glucan" EXACT IUPAC_NAME [IUPAC]
synonym: "glucans" RELATED [ChEBI]
xref: CAS:9037-91-6 {source="ChemIDplus"}
xref: KEGG:C01379
is_a: CHEBI:37164 ! homopolysaccharide
property_value: http://purl.obolibrary.org/obo/chebi/formula "C12H22O11(C6H10O5)n" xsd:string

[Term]
id: CHEBI:37164
name: homopolysaccharide
namespace: chebi_ontology
def: "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." []
subset: 3_STAR
synonym: "homoglycan" RELATED [IUPAC]
synonym: "homopolysaccharide" EXACT IUPAC_NAME [IUPAC]
synonym: "homopolysaccharides" RELATED [ChEBI]
is_a: CHEBI:18154 ! polysaccharide

[Term]
id: CHEBI:37175
name: organic hydride
namespace: chebi_ontology
subset: 3_STAR
synonym: "organic hydrides" RELATED [ChEBI]
is_a: CHEBI:33692 ! hydrides

[Term]
id: CHEBI:37176
name: mononuclear parent hydride
namespace: chebi_ontology
subset: 3_STAR
synonym: "mononuclear hydride" RELATED [ChEBI]
synonym: "mononuclear hydrides" RELATED [IUPAC]
synonym: "mononuclear parent hydrides" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:33692 ! hydrides

[Term]
id: CHEBI:37246
name: elemental sodium
namespace: chebi_ontology
subset: 3_STAR
is_a: CHEBI:26712 ! sodium molecular entity

[Term]
id: CHEBI:37395
name: mucopolysaccharide
namespace: chebi_ontology
alt_id: CHEBI:25425
alt_id: CHEBI:7011
def: "Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid." []
subset: 3_STAR
synonym: "mucopolisacarido" RELATED [ChEBI]
synonym: "mucopolisacaridos" RELATED [IUPAC]
synonym: "Mucopolysaccharid" RELATED [ChEBI]
synonym: "Mucopolysaccharide" EXACT [KEGG_COMPOUND]
synonym: "mucopolysaccharides" EXACT IUPAC_NAME [IUPAC]
synonym: "Mukopolysaccharid" RELATED [ChEBI]
xref: KEGG:C05114
is_a: CHEBI:18085 ! glycosaminoglycan

[Term]
id: CHEBI:37527
name: acid
namespace: chebi_ontology
alt_id: CHEBI:13800
alt_id: CHEBI:13801
alt_id: CHEBI:22209
alt_id: CHEBI:2426
def: "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." []
subset: 3_STAR
synonym: "Acid" EXACT [KEGG_COMPOUND]
synonym: "acid" EXACT IUPAC_NAME [IUPAC]
synonym: "acide" RELATED [IUPAC]
synonym: "acido" RELATED [ChEBI]
synonym: "acids" RELATED [ChEBI]
synonym: "Saeure" RELATED [ChEBI]
synonym: "Saeuren" RELATED [ChEBI]
xref: KEGG:C00174
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:37577
name: heteroatomic molecular entity
namespace: chebi_ontology
def: "A molecular entity consisting of two or more chemical elements." []
subset: 3_STAR
synonym: "chemical compound" RELATED [ChEBI]
synonym: "heteroatomic molecular entities" RELATED [ChEBI]
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:37622
name: carboxamide
namespace: chebi_ontology
alt_id: CHEBI:35354
alt_id: CHEBI:35355
def: "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." []
subset: 3_STAR
synonym: "carboxamides" EXACT IUPAC_NAME [IUPAC]
synonym: "carboxamides" RELATED [ChEBI]
synonym: "primary carboxamide" RELATED [ChEBI]
is_a: CHEBI:33256 ! primary amide
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:36963 ! organooxygen compound
relationship: has_part CHEBI:23004 ! carbamoyl group
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CNOR3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "42.01680" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "41.99799" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C(=O)N([*])[*]" xsd:string

[Term]
id: CHEBI:37826
name: sulfuric acid derivative
namespace: chebi_ontology
subset: 3_STAR
synonym: "sulfuric acid derivative" EXACT [ChEBI]
synonym: "sulfuric acid derivatives" RELATED [ChEBI]
is_a: CHEBI:33424 ! sulfur oxoacid derivative
relationship: has_functional_parent CHEBI:26836 ! sulfuric acid

[Term]
id: CHEBI:37838
name: carboacyl group
namespace: chebi_ontology
def: "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." []
subset: 3_STAR
synonym: "carboacyl groups" EXACT IUPAC_NAME [IUPAC]
synonym: "carboxylic acyl group" EXACT IUPAC_NAME [IUPAC]
synonym: "carboxylic acyl groups" RELATED [IUPAC]
is_a: CHEBI:22221 ! acyl group
relationship: is_substituent_group_from CHEBI:33575 ! carboxylic acid

[Term]
id: CHEBI:37886
name: adrenergic agonist
namespace: chebi_ontology
def: "An agent that selectively binds to and activates adrenergic receptors." []
subset: 3_STAR
synonym: "adrenergic agonists" RELATED [ChEBI]
synonym: "adrenergic receptor agonist" RELATED [ChEBI]
synonym: "adrenoceptor agonists" RELATED [IUPHAR]
synonym: "adrenomimetic" RELATED [ChEBI]
synonym: "adrenomimetics" RELATED [ChEBI]
is_a: CHEBI:37962 ! adrenergic agent

[Term]
id: CHEBI:37962
name: adrenergic agent
namespace: chebi_ontology
def: "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." []
subset: 3_STAR
synonym: "adrenergic agents" RELATED [ChEBI]
synonym: "adrenergic drug" RELATED [ChEBI]
synonym: "adrenergic drugs" RELATED [ChEBI]
synonym: "adrenergic neuron agents" RELATED [ChEBI]
synonym: "adrenergics" RELATED [ChEBI]
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:38077
name: polypyrrole
namespace: chebi_ontology
def: "A compound composed of two or more pyrrole units." []
subset: 3_STAR
synonym: "poly(pyrrole)s" RELATED [ChEBI]
synonym: "polypyrroles" RELATED [ChEBI]
synonym: "PPys" RELATED [ChEBI]
xref: Beilstein:8538310 {source="Beilstein"}
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38101
name: organonitrogen heterocyclic compound
namespace: chebi_ontology
def: "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." []
subset: 3_STAR
synonym: "heterocyclic organonitrogen compounds" RELATED [ChEBI]
synonym: "organonitrogen heterocyclic compounds" RELATED [ChEBI]
is_a: CHEBI:24532 ! organic heterocyclic compound
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:38166
name: organic heteropolycyclic compound
namespace: chebi_ontology
alt_id: CHEBI:25429
alt_id: CHEBI:38075
subset: 3_STAR
synonym: "organic heteropolycyclic compounds" RELATED [ChEBI]
is_a: CHEBI:24532 ! organic heterocyclic compound
is_a: CHEBI:33671 ! heteropolycyclic compound

[Term]
id: CHEBI:38180
name: polycyclic heteroarene
namespace: chebi_ontology
subset: 3_STAR
synonym: "polycyclic heteroarenes" RELATED [ChEBI]
is_a: CHEBI:33833 ! heteroarene

[Term]
id: CHEBI:38323
name: cholinergic drug
namespace: chebi_ontology
def: "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." []
subset: 3_STAR
synonym: "cholinergic agent" RELATED [ChEBI]
synonym: "cholinergic drugs" RELATED [ChEBI]
synonym: "cholinomimetic" RELATED [ChEBI]
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:38324
name: cholinergic agonist
namespace: chebi_ontology
def: "Any drug that binds to and activates cholinergic receptors." []
subset: 3_STAR
synonym: "acetylcholine agonist" RELATED [ChEBI]
synonym: "acetylcholine agonists" RELATED [ChEBI]
synonym: "acetylcholine receptor agonist" RELATED [IUPHAR]
synonym: "cholinergic agonists" RELATED [ChEBI]
synonym: "cholinomimetic" RELATED [ChEBI]
synonym: "cholinomimetics" RELATED [ChEBI]
is_a: CHEBI:38323 ! cholinergic drug

[Term]
id: CHEBI:38325
name: muscarinic agonist
namespace: chebi_ontology
def: "Any drug that binds to and activates a muscarinic cholinergic receptor." []
subset: 3_STAR
synonym: "muscarinic acetylcholine receptor agonist" RELATED [ChEBI]
synonym: "muscarinic agonists" RELATED [ChEBI]
synonym: "muscarinic cholinergic agonist" RELATED [ChEBI]
synonym: "muscarinic cholinergic agonists" RELATED [ChEBI]
is_a: CHEBI:38324 ! cholinergic agonist

[Term]
id: CHEBI:38631
name: aminoalkylindole
namespace: chebi_ontology
alt_id: CHEBI:22503
alt_id: CHEBI:24792
subset: 3_STAR
synonym: "aminoalkylindoles" RELATED [ChEBI]
is_a: CHEBI:24828 ! indoles

[Term]
id: CHEBI:38700
name: organic sodium salt
namespace: chebi_ontology
subset: 3_STAR
synonym: "organic sodium salt" EXACT [ChEBI]
synonym: "organic sodium salts" RELATED [ChEBI]
is_a: CHEBI:24868 ! organic salt
is_a: CHEBI:26714 ! sodium salt

[Term]
id: CHEBI:38716
name: carboxylic acid dianion
namespace: chebi_ontology
def: "Any dianion containing at least one carboxy group." []
subset: 3_STAR
synonym: "carboxylic acid dianion" EXACT [ChEBI]
synonym: "carboxylic acid dianions" RELATED [ChEBI]
is_a: CHEBI:29067 ! carboxylic acid anion

[Term]
id: CHEBI:38958
name: indole alkaloid
namespace: chebi_ontology
alt_id: CHEBI:24795
alt_id: CHEBI:5901
def: "An alkaloid containing an indole skeleton." []
subset: 3_STAR
synonym: "Indole alkaloid" EXACT [KEGG_COMPOUND]
synonym: "indole alkaloids" RELATED [ChEBI]
xref: KEGG:C06073
xref: Wikipedia:Indole_alkaloid
is_a: CHEBI:22315 ! alkaloid
relationship: has_part CHEBI:73398 ! indole skeleton

[Term]
id: CHEBI:39141
name: Bronsted acid
namespace: chebi_ontology
def: "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." []
subset: 3_STAR
synonym: "acide de Bronsted" RELATED [IUPAC]
synonym: "Bronsted acid" EXACT IUPAC_NAME [IUPAC]
synonym: "Bronsted-Saeure" RELATED [ChEBI]
synonym: "donneur d'hydron" RELATED [IUPAC]
synonym: "hydron donor" RELATED [IUPAC]
is_a: CHEBI:17891 ! donor
is_a: CHEBI:37527 ! acid

[Term]
id: CHEBI:39142
name: Bronsted base
namespace: chebi_ontology
def: "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." []
subset: 3_STAR
synonym: "accepteur d'hydron" RELATED [IUPAC]
synonym: "base de Bronsted" RELATED [IUPAC]
synonym: "Bronsted base" EXACT IUPAC_NAME [IUPAC]
synonym: "Bronsted-Base" RELATED [ChEBI]
synonym: "hydron acceptor" RELATED [IUPAC]
is_a: CHEBI:15339 ! acceptor
is_a: CHEBI:22695 ! base

[Term]
id: CHEBI:39144
name: Lewis base
namespace: chebi_ontology
def: "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." []
subset: 3_STAR
synonym: "base de Lewis" RELATED [IUPAC]
synonym: "donneur d'une paire d'electrons" RELATED [ChEBI]
synonym: "electron donor" RELATED [ChEBI]
synonym: "Lewis base" EXACT IUPAC_NAME [IUPAC]
synonym: "Lewis-Base" RELATED [ChEBI]
is_a: CHEBI:17891 ! donor
is_a: CHEBI:22695 ! base

[Term]
id: CHEBI:39745
name: dihydrogenphosphate
namespace: chebi_ontology
alt_id: CHEBI:29137
alt_id: CHEBI:39739
def: "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." []
subset: 3_STAR
synonym: "[PO2(OH)2](-)" RELATED [IUPAC]
synonym: "dihydrogen(tetraoxidophosphate)(1-)" EXACT IUPAC_NAME [IUPAC]
synonym: "dihydrogenphosphate" EXACT IUPAC_NAME [IUPAC]
synonym: "DIHYDROGENPHOSPHATE ION" RELATED [PDBeChem]
synonym: "dihydrogentetraoxophosphate(1-)" EXACT IUPAC_NAME [IUPAC]
synonym: "dihydrogentetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC]
synonym: "dihydroxidodioxidophosphate(1-)" EXACT IUPAC_NAME [IUPAC]
synonym: "H2PO4(-)" RELATED [IUPAC]
xref: DrugBank:DB02831
xref: Gmelin:1999 {source="Gmelin"}
xref: PDBeChem:2HP
is_a: CHEBI:35780 ! phosphate ion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: is_conjugate_acid_of CHEBI:43474 ! hydrogenphosphate
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O4P" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-M" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "96.98724" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "96.96962" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OP([O-])(=O)O[H]" xsd:string

[Term]
id: CHEBI:41609
name: carbonate
namespace: chebi_ontology
alt_id: CHEBI:29201
alt_id: CHEBI:41605
subset: 3_STAR
synonym: "[CO3](2-)" RELATED [IUPAC]
synonym: "carbonate" EXACT [IUPAC]
synonym: "CARBONATE ION" RELATED [PDBeChem]
synonym: "CO3(2-)" RELATED [ChEBI]
synonym: "Karbonat" RELATED [ChEBI]
synonym: "trioxidocarbonate(2-)" EXACT IUPAC_NAME [IUPAC]
xref: Beilstein:3600898 {source="Beilstein"}
xref: CAS:3812-32-6 {source="ChemIDplus"}
xref: Gmelin:1559 {source="Gmelin"}
xref: PDBeChem:CO3
is_a: CHEBI:35604 ! carbon oxoanion
relationship: is_conjugate_base_of CHEBI:17544 ! hydrogencarbonate
property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CO3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-L" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "60.00890" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.98584" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([O-])=O" xsd:string

[Term]
id: CHEBI:43176
name: hydroxy group
namespace: chebi_ontology
alt_id: CHEBI:24706
alt_id: CHEBI:43171
subset: 3_STAR
synonym: "-OH" RELATED [IUPAC]
synonym: "hydroxy" EXACT IUPAC_NAME [IUPAC]
synonym: "HYDROXY GROUP" EXACT [PDBeChem]
synonym: "hydroxy group" EXACT [UniProt]
synonym: "hydroxyl" RELATED [ChEBI]
synonym: "hydroxyl group" RELATED [ChEBI]
xref: PDBeChem:OH
is_a: CHEBI:33246 ! inorganic group
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "HO" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "17.00734" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.00274" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "*O[H]" xsd:string

[Term]
id: CHEBI:43474
name: hydrogenphosphate
namespace: chebi_ontology
alt_id: CHEBI:29139
alt_id: CHEBI:43470
def: "A phosphate ion that is the conjugate base of dihydrogenphosphate." []
subset: 3_STAR
synonym: "[P(OH)O3](2-)" RELATED [MolBase]
synonym: "[PO3(OH)](2-)" RELATED [IUPAC]
synonym: "HPO4(2-)" RELATED [IUPAC]
synonym: "hydrogen phosphate" RELATED [ChEBI]
synonym: "hydrogen(tetraoxidophosphate)(2-)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydrogenphosphate" EXACT IUPAC_NAME [IUPAC]
synonym: "HYDROGENPHOSPHATE ION" RELATED [PDBeChem]
synonym: "hydrogentetraoxophosphate(2-)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydrogentetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydroxidotrioxidophosphate(2-)" EXACT IUPAC_NAME [IUPAC]
synonym: "INORGANIC PHOSPHATE GROUP" RELATED [PDBeChem]
synonym: "phosphate" RELATED [UniProt]
xref: Gmelin:1998 {source="Gmelin"}
xref: MolBase:1628
xref: PDBeChem:PI
xref: PDBeChem:PO4
is_a: CHEBI:35780 ! phosphate ion
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: has_role CHEBI:23357 ! cofactor
relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite
relationship: is_conjugate_acid_of CHEBI:18367 ! phosphate(3-)
relationship: is_conjugate_base_of CHEBI:39745 ! dihydrogenphosphate
property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "HO4P" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-L" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "95.97930" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.96234" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "OP([O-])([O-])=O" xsd:string

[Term]
id: CHEBI:45696
name: hydrogensulfate
namespace: chebi_ontology
alt_id: CHEBI:29199
alt_id: CHEBI:45693
subset: 3_STAR
synonym: "[SO3(OH)](-)" RELATED [IUPAC]
synonym: "HSO4(-)" RELATED [IUPAC]
synonym: "HYDROGEN SULFATE" RELATED [PDBeChem]
synonym: "hydrogen(tetraoxidosulfate)(1-)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydrogensulfate" EXACT [IUPAC]
synonym: "hydrogensulfate(1-)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydrogentetraoxosulfate(1-)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydrogentetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC]
synonym: "hydroxidotrioxidosulfate(1-)" EXACT IUPAC_NAME [IUPAC]
xref: Gmelin:2121 {source="Gmelin"}
is_a: CHEBI:33482 ! sulfur oxoanion
relationship: is_conjugate_acid_of CHEBI:16189 ! sulfate
relationship: is_conjugate_base_of CHEBI:26836 ! sulfuric acid
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "HO4S" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-M" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "97.07154" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "96.96010" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OS([O-])(=O)=O" xsd:string

[Term]
id: CHEBI:46629
name: oxo group
namespace: chebi_ontology
alt_id: CHEBI:29353
alt_id: CHEBI:44607
subset: 3_STAR
synonym: "=O" RELATED [IUPAC]
synonym: "oxo" EXACT IUPAC_NAME [IUPAC]
synonym: "OXO GROUP" EXACT [PDBeChem]
xref: PDBeChem:O
is_a: CHEBI:33246 ! inorganic group
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=*" xsd:string

[Term]
id: CHEBI:46787
name: solvent
namespace: chebi_ontology
def: "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." []
subset: 3_STAR
synonym: "Loesungsmittel" RELATED [ChEBI]
synonym: "solvant" RELATED [ChEBI]
synonym: "solvents" RELATED [ChEBI]
xref: Wikipedia:Solvent
is_a: CHEBI:33232 ! application
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:46883
name: carboxy group
namespace: chebi_ontology
alt_id: CHEBI:23025
alt_id: CHEBI:41420
subset: 3_STAR
synonym: "-C(O)OH" RELATED [IUPAC]
synonym: "-CO2H" RELATED [ChEBI]
synonym: "-COOH" RELATED [IUPAC]
synonym: "carboxy" EXACT IUPAC_NAME [IUPAC]
synonym: "CARBOXY GROUP" EXACT [PDBeChem]
synonym: "carboxyl group" RELATED [ChEBI]
xref: PDBeChem:FMT
is_a: CHEBI:33249 ! organyl group
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01744" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(=O)O" xsd:string

[Term]
id: CHEBI:47622
name: acetate ester
namespace: chebi_ontology
alt_id: CHEBI:13244
alt_id: CHEBI:13799
alt_id: CHEBI:22189
alt_id: CHEBI:2406
def: "Any carboxylic ester where the carboxylic acid component is acetic acid." []
subset: 3_STAR
synonym: "acetate" RELATED [ChEBI]
synonym: "acetate esters" RELATED [ChEBI]
synonym: "acetates" RELATED [ChEBI]
synonym: "Acetic ester" RELATED [KEGG_COMPOUND]
synonym: "Acetyl ester" RELATED [KEGG_COMPOUND]
synonym: "acetyl esters" RELATED [ChEBI]
synonym: "an acetyl ester" RELATED [UniProt]
xref: KEGG:C01883
xref: Wikipedia:Acetate#Esters
is_a: CHEBI:33308 ! carboxylic ester
relationship: has_functional_parent CHEBI:15366 ! acetic acid
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3O2R" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "59.04400" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.01330" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(=O)O[*]" xsd:string

[Term]
id: CHEBI:47891
name: steroid acid
namespace: chebi_ontology
def: "Any steroid substituted by at least one carboxy group." []
subset: 3_STAR
synonym: "steroid acids" RELATED [ChEBI]
is_a: CHEBI:35341 ! steroid
is_a: CHEBI:64709 ! organic acid
relationship: is_conjugate_acid_of CHEBI:50160 ! steroid acid anion

[Term]
id: CHEBI:48154
name: sulfur oxide
namespace: chebi_ontology
subset: 3_STAR
synonym: "oxides of sulfur" RELATED [ChEBI]
synonym: "Schwefeloxide" RELATED [ChEBI]
synonym: "sulfur oxides" RELATED [ChEBI]
is_a: CHEBI:24836 ! inorganic oxide
is_a: CHEBI:26835 ! sulfur molecular entity

[Term]
id: CHEBI:48354
name: polar solvent
namespace: chebi_ontology
def: "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." []
subset: 3_STAR
synonym: "polar solvent" EXACT IUPAC_NAME [IUPAC]
synonym: "polar solvents" RELATED [ChEBI]
is_a: CHEBI:46787 ! solvent

[Term]
id: CHEBI:48356
name: protic solvent
namespace: chebi_ontology
def: "A polar solvent that is capable of acting as a hydron (proton) donor." []
subset: 3_STAR
synonym: "protogenic solvent" EXACT IUPAC_NAME [IUPAC]
is_a: CHEBI:39141 ! Bronsted acid
is_a: CHEBI:48354 ! polar solvent

[Term]
id: CHEBI:48539
name: alpha-adrenergic drug
namespace: chebi_ontology
def: "Any drug that acts on an alpha-adrenergic receptor." []
subset: 3_STAR
synonym: "alpha-adrenergic drugs" RELATED [ChEBI]
is_a: CHEBI:37962 ! adrenergic agent

[Term]
id: CHEBI:48705
name: agonist
namespace: chebi_ontology
def: "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." []
subset: 3_STAR
synonym: "agonist" EXACT IUPAC_NAME [IUPAC]
synonym: "agonista" RELATED [ChEBI]
synonym: "agoniste" RELATED [ChEBI]
synonym: "agonists" RELATED [ChEBI]
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:49637
name: hydrogen atom
namespace: chebi_ontology
alt_id: CHEBI:24634
alt_id: CHEBI:49636
subset: 3_STAR
synonym: "1H" RELATED [IUPAC]
synonym: "H" RELATED [IUPAC]
synonym: "hidrogeno" RELATED [ChEBI]
synonym: "hydrogen" EXACT IUPAC_NAME [IUPAC]
synonym: "hydrogen" RELATED [ChEBI]
synonym: "hydrogene" RELATED [ChEBI]
synonym: "Wasserstoff" RELATED [ChEBI]
xref: WebElements:H
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33559 ! s-block element atom
relationship: has_role CHEBI:33937 ! macronutrient
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "H" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YZCKVEUIGOORGS-UHFFFAOYSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "1.00794" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1.00783" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]" xsd:string

[Term]
id: CHEBI:50047
name: organic amino compound
namespace: chebi_ontology
def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." []
subset: 3_STAR
synonym: "organic amino compounds" RELATED [ChEBI]
is_a: CHEBI:35352 ! organonitrogen compound
relationship: has_parent_hydride CHEBI:16134 ! ammonia
relationship: has_role CHEBI:39142 ! Bronsted base

[Term]
id: CHEBI:50160
name: steroid acid anion
namespace: chebi_ontology
def: "Any anion formed by loss of a proton from a steroid acid." []
subset: 3_STAR
synonym: "steroid acid anions" RELATED [ChEBI]
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: is_conjugate_base_of CHEBI:47891 ! steroid acid

[Term]
id: CHEBI:50297
name: canonical nucleotide residue
namespace: chebi_ontology
subset: 3_STAR
synonym: "canonical nucleotide residues" RELATED [ChEBI]
is_a: CHEBI:50319 ! nucleotide residue

[Term]
id: CHEBI:50298
name: canonical deoxyribonucleotide residue
namespace: chebi_ontology
subset: 3_STAR
synonym: "canonical deoxyribonucleotide residues" RELATED [ChEBI]
is_a: CHEBI:50297 ! canonical nucleotide residue

[Term]
id: CHEBI:50299
name: canonical ribonucleotide residue
namespace: chebi_ontology
subset: 3_STAR
synonym: "canonical ribonucleotide residues" RELATED [ChEBI]
is_a: CHEBI:50297 ! canonical nucleotide residue

[Term]
id: CHEBI:50312
name: onium compound
namespace: chebi_ontology
subset: 1_STAR
is_a: CHEBI:37577 ! heteroatomic molecular entity

[Term]
id: CHEBI:50313
name: onium cation
namespace: chebi_ontology
def: "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." []
subset: 3_STAR
synonym: "onium cations" EXACT IUPAC_NAME [IUPAC]
synonym: "onium cations" RELATED [ChEBI]
synonym: "onium ion" RELATED [ChEBI]
synonym: "onium ions" RELATED [ChEBI]
is_a: CHEBI:50312 ! onium compound

[Term]
id: CHEBI:50319
name: nucleotide residue
namespace: chebi_ontology
subset: 3_STAR
synonym: "nucleotide residues" RELATED [ChEBI]
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:50320
name: nucleoside residue
namespace: chebi_ontology
subset: 3_STAR
synonym: "nucleoside residues" RELATED [ChEBI]
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:50514
name: vasoconstrictor agent
namespace: chebi_ontology
def: "Drug used to cause constriction of the blood vessels." []
subset: 3_STAR
is_a: CHEBI:35554 ! cardiovascular drug

[Term]
id: CHEBI:50860
name: organic molecular entity
namespace: chebi_ontology
alt_id: CHEBI:25700
alt_id: CHEBI:33244
def: "Any molecular entity that contains carbon." []
subset: 3_STAR
synonym: "organic compounds" RELATED [ChEBI]
synonym: "organic entity" RELATED [ChEBI]
synonym: "organic molecular entities" RELATED [ChEBI]
is_a: CHEBI:33582 ! carbon group molecular entity
relationship: has_part CHEBI:27594 ! carbon atom

[Term]
id: CHEBI:50906
name: role
namespace: chebi_ontology
def: "A role is particular behaviour which a material entity may exhibit." []
subset: 3_STAR
is_a: PATO:0000001 ! quality

[Term]
id: CHEBI:50910
name: neurotoxin
namespace: chebi_ontology
alt_id: CHEBI:50911
def: "A poison that interferes with the functions of the nervous system." []
subset: 3_STAR
synonym: "agente neurotoxico" RELATED [ChEBI]
synonym: "nerve poison" RELATED [ChEBI]
synonym: "nerve poisons" RELATED [ChEBI]
synonym: "neurotoxic agent" RELATED [ChEBI]
synonym: "neurotoxic agents" RELATED [ChEBI]
synonym: "neurotoxicant" RELATED [ChEBI]
synonym: "neurotoxins" RELATED [ChEBI]
xref: Wikipedia:Neurotoxin
is_a: CHEBI:52209 ! aetiopathogenetic role
is_a: CHEBI:64909 ! poison

[Term]
id: CHEBI:50994
name: primary amino compound
namespace: chebi_ontology
def: "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." []
subset: 3_STAR
synonym: "primary amino compounds" RELATED [ChEBI]
is_a: CHEBI:50047 ! organic amino compound
relationship: is_conjugate_base_of CHEBI:65296 ! primary ammonium ion

[Term]
id: CHEBI:51086
name: chemical role
namespace: chebi_ontology
def: "A role played by the molecular entity or part thereof within a chemical context." []
subset: 3_STAR
is_a: CHEBI:50906 ! role

[Term]
id: CHEBI:51143
name: nitrogen molecular entity
namespace: chebi_ontology
alt_id: CHEBI:25556
alt_id: CHEBI:7594
subset: 3_STAR
synonym: "nitrogen compounds" RELATED [ChEBI]
synonym: "nitrogen molecular entities" RELATED [ChEBI]
synonym: "Nitrogenous compounds" RELATED [KEGG_COMPOUND]
xref: KEGG:C06061
is_a: CHEBI:33302 ! pnictogen molecular entity
relationship: has_part CHEBI:25555 ! nitrogen atom

[Term]
id: CHEBI:51151
name: dipolar compound
namespace: chebi_ontology
def: "An  organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." []
subset: 3_STAR
synonym: "dipolar compounds" RELATED [ChEBI]
is_a: CHEBI:72695 ! organic molecule

[Term]
id: CHEBI:51422
name: organodiyl group
namespace: chebi_ontology
def: "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." []
subset: 3_STAR
synonym: "organodiyl groups" RELATED [ChEBI]
is_a: CHEBI:51446 ! organic divalent group

[Term]
id: CHEBI:51446
name: organic divalent group
namespace: chebi_ontology
subset: 1_STAR
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:51447
name: organic univalent group
namespace: chebi_ontology
subset: 1_STAR
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:51958
name: organic polycyclic compound
namespace: chebi_ontology
subset: 3_STAR
synonym: "organic polycyclic compounds" RELATED [ChEBI]
is_a: CHEBI:33635 ! polycyclic compound
is_a: CHEBI:33832 ! organic cyclic compound

[Term]
id: CHEBI:52206
name: biochemical role
namespace: chebi_ontology
def: "A biological role played by the molecular entity or part thereof within a biochemical context." []
subset: 3_STAR
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:52209
name: aetiopathogenetic role
namespace: chebi_ontology
def: "A role played by the molecular entity or part thereof which causes the development of a pathological process." []
subset: 3_STAR
synonym: "etiopathogenetic agent" RELATED [ChEBI]
synonym: "etiopathogenetic role" RELATED [ChEBI]
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:52210
name: pharmacological role
namespace: chebi_ontology
def: "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." []
subset: 3_STAR
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:52211
name: physiological role
namespace: chebi_ontology
subset: 1_STAR
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:52217
name: pharmaceutical
namespace: chebi_ontology
alt_id: CHEBI:33293
alt_id: CHEBI:33294
def: "Any substance introduced into a living organism with therapeutic or diagnostic purpose." []
subset: 3_STAR
synonym: "farmaco" RELATED [ChEBI]
synonym: "medicament" RELATED [ChEBI]
synonym: "pharmaceuticals" RELATED [ChEBI]
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:52845
name: cyclic organic group
namespace: chebi_ontology
def: "An organic group that consists of a closed ring. It may be a substituent or a skeleton." []
subset: 3_STAR
synonym: "cyclic organic groups" RELATED [ChEBI]
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:53000
name: epitope
namespace: chebi_ontology
def: "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." []
subset: 3_STAR
synonym: "antigenic determinant" RELATED [ChEBI]
synonym: "epitope function" RELATED [ChEBI]
synonym: "epitope role" RELATED [ChEBI]
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:53309
name: polyanionic macromolecule
namespace: chebi_ontology
def: "A polymer carrying multiple negative charges." []
subset: 3_STAR
synonym: "polyanion" RELATED [ChEBI]
synonym: "polyanions" RELATED [SUBMITTER]
is_a: CHEBI:53368 ! ionic macromolecule

[Term]
id: CHEBI:53368
name: ionic macromolecule
namespace: chebi_ontology
def: "A macromolecule containing ionic groups." []
subset: 3_STAR
synonym: "ionic polymer" RELATED [ChEBI]
synonym: "polyionic macromolecule" RELATED [ChEBI]
is_a: CHEBI:33839 ! macromolecule

[Term]
id: CHEBI:5391
name: glucagon
namespace: chebi_ontology
def: "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence." []
subset: 3_STAR
synonym: "Glucagon" EXACT [KEGG_COMPOUND]
synonym: "glucagon" RELATED INN [ChemIDplus]
synonym: "Glucagone" RELATED [ChemIDplus]
synonym: "glucagonum" RELATED INN [ChemIDplus]
synonym: "His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr" RELATED [ChEBI]
synonym: "His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr" RELATED [ChemIDplus]
synonym: "HSQGTFTSDYSKYLDSRRAQDFVQWLMNT" RELATED [ChEBI]
synonym: "L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine" EXACT IUPAC_NAME [IUPAC]
xref: CAS:16941-32-5 {source="ChemIDplus"}
xref: CAS:9007-92-5 {source="KEGG COMPOUND"}
xref: CAS:9007-92-5 {source="ChemIDplus"}
xref: Drug_Central:2994 {source="DrugCentral"}
xref: DrugBank:DB00040
xref: KEGG:C01501
xref: KEGG:D00116
xref: PMID:21940356 {source="Europe PMC"}
xref: PMID:22014161 {source="Europe PMC"}
xref: PMID:22154917 {source="Europe PMC"}
xref: PMID:22166985 {source="Europe PMC"}
xref: PMID:22167521 {source="Europe PMC"}
xref: PMID:22214853 {source="Europe PMC"}
xref: PMID:22227186 {source="Europe PMC"}
xref: PMID:22286080 {source="Europe PMC"}
xref: PMID:22294753 {source="Europe PMC"}
xref: PMID:22318544 {source="Europe PMC"}
xref: PMID:22334714 {source="Europe PMC"}
xref: PMID:22399501 {source="Europe PMC"}
xref: PMID:22438981 {source="Europe PMC"}
xref: PMID:22454291 {source="Europe PMC"}
xref: Reaxys:13191924 {source="Reaxys"}
xref: Wikipedia:Glucagon
is_a: CHEBI:25905 ! peptide hormone
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C153H225N43O49S" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MASNOZXLGMXCHN-ZLPAWPGGSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "3482.74700" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "3480.61570" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O" xsd:string

[Term]
id: CHEBI:5686
name: heterocyclic compound
namespace: chebi_ontology
def: "A cyclic compound having as ring members atoms of at least two different elements." []
subset: 3_STAR
synonym: "compuesto heterociclico" RELATED [IUPAC]
synonym: "compuestos heterociclicos" RELATED [IUPAC]
synonym: "heterocycle" RELATED [ChEBI]
synonym: "Heterocyclic compound" EXACT [KEGG_COMPOUND]
synonym: "heterocyclic compounds" RELATED [ChEBI]
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:57887
name: tryptaminium
namespace: chebi_ontology
def: "An  ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." []
subset: 3_STAR
synonym: "2-(1H-indol-3-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC]
synonym: "tryptamine" RELATED [UniProt]
synonym: "tryptaminium cation" RELATED [ChEBI]
synonym: "tryptaminium(1+)" RELATED [ChEBI]
xref: Gmelin:533978 {source="Gmelin"}
is_a: CHEBI:65296 ! primary ammonium ion
relationship: has_role CHEBI:75771 ! mouse metabolite
relationship: has_role CHEBI:76924 ! plant metabolite
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_acid_of CHEBI:16765 ! tryptamine
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H13N2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "APJYDQYYACXCRM-UHFFFAOYSA-O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "161.22310" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "161.10732" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCc1c[nH]c2ccccc12" xsd:string

[Term]
id: CHEBI:57977
name: bilirubin(2-)
namespace: chebi_ontology
def: "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3." []
subset: 3_STAR
synonym: "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate" RELATED [ChEBI]
synonym: "bilirubin dianion" RELATED [ChEBI]
synonym: "bilirubin IXalpha" RELATED [UniProt]
xref: Beilstein:4083310 {source="Beilstein"}
is_a: CHEBI:28965 ! dicarboxylic acid dianion
is_a: CHEBI:59252 ! linear tetrapyrrole anion
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_base_of CHEBI:16990 ! bilirubin IXalpha
property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C33H34N4O6" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/p-2/b26-13-,27-14-" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BPYKTIZUTYGOLE-IFADSCNNSA-L" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "582.64630" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "582.24893" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC1=C(C=C)\\C(NC1=O)=C\\c1[nH]c(Cc2[nH]c(\\C=C3NC(=O)C(C=C)=C/3C)c(C)c2CCC([O-])=O)c(CCC([O-])=O)c1C" xsd:string

[Term]
id: CHEBI:58958
name: organosulfate oxoanion
namespace: chebi_ontology
def: "An organic anion of general formula RS(=O)2O(-) where R is an organyl group." []
subset: 3_STAR
synonym: "organosulfate oxoanions" RELATED [ChEBI]
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:33482 ! sulfur oxoanion
relationship: has_functional_parent CHEBI:16189 ! sulfate
relationship: is_conjugate_base_of CHEBI:25704 ! organic sulfate
property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06300" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S(=O)(=O)O[*]" xsd:string

[Term]
id: CHEBI:59252
name: linear tetrapyrrole anion
namespace: chebi_ontology
def: "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound." []
subset: 3_STAR
synonym: "acyclic tetrapyrrole anion" RELATED [ChEBI]
synonym: "acyclic tetrapyrrole anions" RELATED [ChEBI]
synonym: "linear tetrapyrrole anions" RELATED [ChEBI]
is_a: CHEBI:25696 ! organic anion

[Term]
id: CHEBI:59698
name: phosphoric acids
namespace: chebi_ontology
def: "Compounds containing one or more phosphoric acid units." []
subset: 3_STAR
is_a: CHEBI:33457 ! phosphorus oxoacid

[Term]
id: CHEBI:59740
name: nucleophilic reagent
namespace: chebi_ontology
def: "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." []
subset: 3_STAR
synonym: "nucleophile" RELATED [ChEBI]
synonym: "nucleophiles" RELATED [ChEBI]
synonym: "nucleophilic reagents" RELATED [ChEBI]
is_a: CHEBI:33893 ! reagent
is_a: CHEBI:39144 ! Lewis base

[Term]
id: CHEBI:59999
name: chemical substance
namespace: chebi_ontology
def: "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." []
subset: 3_STAR
synonym: "Chemische Substanz" RELATED [ChEBI]
is_a: CHEBI:24431 ! chemical entity

[Term]
id: CHEBI:60004
name: mixture
namespace: chebi_ontology
def: "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." []
subset: 3_STAR
synonym: "Mischung" RELATED [ChEBI]
is_a: CHEBI:59999 ! chemical substance

[Term]
id: CHEBI:60027
name: polymer
namespace: chebi_ontology
def: "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." []
subset: 3_STAR
synonym: "Kunststoff" RELATED [ChEBI]
synonym: "Polymer" EXACT [ChEBI]
xref: Wikipedia:Polymer
is_a: CHEBI:60004 ! mixture
relationship: has_part CHEBI:33839 ! macromolecule

[Term]
id: CHEBI:60164
name: ionic polymer
namespace: chebi_ontology
def: "An ionic polymer is a polymer, composed of ionic macromolecules." []
subset: 3_STAR
synonym: "polyionic polymer" RELATED [ChEBI]
is_a: CHEBI:60027 ! polymer
relationship: has_part CHEBI:53368 ! ionic macromolecule

[Term]
id: CHEBI:60242
name: monovalent inorganic cation
namespace: chebi_ontology
def: "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." []
subset: 3_STAR
synonym: "a monovalent cation" RELATED [UniProt]
is_a: CHEBI:36915 ! inorganic cation

[Term]
id: CHEBI:60466
name: peptide zwitterion
namespace: chebi_ontology
def: "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." []
subset: 3_STAR
synonym: "a peptide" RELATED [UniProt]
synonym: "peptide zwitterions" RELATED [ChEBI]
is_a: CHEBI:27369 ! zwitterion
relationship: is_tautomer_of CHEBI:16670 ! peptide
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R(C2H2NOR)n" xsd:string

[Term]
id: CHEBI:60926
name: amino monosaccharide
namespace: chebi_ontology
def: "Any  amino sugar that is a monosaccharide in which one alcoholic hydroxy group is replaced by an amino group." []
subset: 3_STAR
synonym: "amino monosaccharides" RELATED [ChEBI]
is_a: CHEBI:28963 ! amino sugar

[Term]
id: CHEBI:61120
name: nucleobase-containing molecular entity
namespace: chebi_ontology
def: "Any compound that has a nucleobase as a part." []
subset: 3_STAR
synonym: "nucleobase-containing compound" RELATED [SUBMITTER]
synonym: "nucleobase-containing compounds" RELATED [ChEBI]
synonym: "nucleobase-containing molecular entities" RELATED [ChEBI]
is_a: CHEBI:33833 ! heteroarene
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: has_functional_parent CHEBI:18282 ! nucleobase

[Term]
id: CHEBI:61469
name: polyanionic polymer
namespace: chebi_ontology
def: "A polymer, composed of polyanion macromolecules." []
subset: 3_STAR
synonym: "polyanion" RELATED [ChEBI]
synonym: "polyanions" RELATED [ChEBI]
is_a: CHEBI:60164 ! ionic polymer
relationship: has_part CHEBI:53309 ! polyanionic macromolecule

[Term]
id: CHEBI:63248
name: oxidising agent
namespace: chebi_ontology
def: "A substance that removes electrons from another reactant in a redox reaction." []
subset: 3_STAR
synonym: "oxidant" RELATED [ChEBI]
synonym: "oxidants" RELATED [ChEBI]
synonym: "oxidiser" RELATED [ChEBI]
synonym: "oxidisers" RELATED [ChEBI]
synonym: "oxidising agents" RELATED [ChEBI]
synonym: "oxidizer" RELATED [ChEBI]
synonym: "oxidizers" RELATED [ChEBI]
synonym: "oxidizing agent" RELATED [ChEBI]
synonym: "oxidizing agents" RELATED [ChEBI]
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:63299
name: carbohydrate derivative
namespace: chebi_ontology
def: "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." []
subset: 3_STAR
synonym: "carbohydrate derivatives" RELATED [ChEBI]
synonym: "derivatised carbohydrate" RELATED [ChEBI]
synonym: "derivatised carbohydrates" RELATED [ChEBI]
synonym: "derivatized carbohydrate" RELATED [ChEBI]
synonym: "derivatized carbohydrates" RELATED [ChEBI]
is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives
relationship: has_functional_parent CHEBI:16646 ! carbohydrate

[Term]
id: CHEBI:63436
name: carbohydrate acid derivative
namespace: chebi_ontology
def: "A carbohydrate derivative that is formally obtained from a carbohydrate acid." []
subset: 3_STAR
synonym: "carbohydrate acid derivatives" RELATED [ChEBI]
is_a: CHEBI:63299 ! carbohydrate derivative
relationship: has_functional_parent CHEBI:33720 ! carbohydrate acid
relationship: is_conjugate_acid_of CHEBI:63551 ! carbohydrate acid derivative anion

[Term]
id: CHEBI:63534
name: monoamine
namespace: chebi_ontology
def: "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." []
subset: 3_STAR
synonym: "monoamines" RELATED [ChEBI]
synonym: "naturally occurring monoamine" RELATED [ChEBI]
synonym: "naturally occurring monoamines" RELATED [ChEBI]
xref: PMID:21822758 {source="Europe PMC"}
xref: PMID:21993877 {source="Europe PMC"}
xref: PMID:22005599 {source="Europe PMC"}
xref: PMID:22082101 {source="Europe PMC"}
xref: PMID:22153577 {source="Europe PMC"}
xref: PMID:22213370 {source="Europe PMC"}
xref: PMID:22218931 {source="Europe PMC"}
xref: PMID:22342987 {source="Europe PMC"}
xref: PMID:22371656 {source="Europe PMC"}
is_a: CHEBI:64365 ! aralkylamino compound

[Term]
id: CHEBI:63551
name: carbohydrate acid derivative anion
namespace: chebi_ontology
def: "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." []
subset: 3_STAR
synonym: "carbohydrate acid anion derivative" RELATED [ChEBI]
synonym: "carbohydrate acid anion derivatives" RELATED [ChEBI]
synonym: "carbohydrate acid derivative anions" RELATED [ChEBI]
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: has_functional_parent CHEBI:33721 ! carbohydrate acid anion
relationship: is_conjugate_base_of CHEBI:63436 ! carbohydrate acid derivative

[Term]
id: CHEBI:64047
name: food additive
namespace: chebi_ontology
def: "Any substance which is added to food to preserve or enhance its flavour and/or appearance." []
subset: 3_STAR
synonym: "food additives" RELATED [ChEBI]
xref: Wikipedia:Food_additive
is_a: CHEBI:33232 ! application
is_a: CHEBI:78295 ! food component

[Term]
id: CHEBI:64049
name: food acidity regulator
namespace: chebi_ontology
def: "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." []
subset: 3_STAR
synonym: "acidity regulator" RELATED [ChEBI]
synonym: "acidity regulators" RELATED [ChEBI]
synonym: "food acidity regulators" RELATED [ChEBI]
synonym: "pH control agent" RELATED [ChEBI]
synonym: "pH control agents" RELATED [ChEBI]
xref: Wikipedia:Acidity_regulator
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:64365
name: aralkylamino compound
namespace: chebi_ontology
def: "An organic amino compound in which an aminoalkyl group is linked to an arene." []
subset: 3_STAR
synonym: "aralkylamino compounds" RELATED [ChEBI]
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:64628
name: somatostatin
namespace: chebi_ontology
def: "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14." []
subset: 3_STAR
synonym: "Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]" RELATED [ChEBI]
synonym: "L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide" EXACT IUPAC_NAME [IUPAC]
synonym: "L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide" RELATED [ChemIDplus]
synonym: "somatostatin" RELATED INN [KEGG_DRUG]
synonym: "Somatostatin-1" RELATED [KEGG_COMPOUND]
synonym: "Somatostatin-14" RELATED [KEGG_COMPOUND]
synonym: "somatostatina" RELATED INN [ChemIDplus]
synonym: "somatostatine" RELATED INN [ChemIDplus]
synonym: "somatostatinum" RELATED INN [ChemIDplus]
synonym: "Synthetic growth hormone release-inhibiting hormone" RELATED [ChemIDplus]
xref: CAS:38916-34-6 {source="KEGG DRUG"}
xref: CAS:38916-34-6 {source="ChemIDplus"}
xref: Drug_Central:2997 {source="DrugCentral"}
xref: HMDB:HMDB0013072
xref: KEGG:C16022
xref: KEGG:D07431
xref: LINCS:LSM-5326
xref: PMID:21922516 {source="Europe PMC"}
xref: PMID:22129035 {source="Europe PMC"}
xref: PMID:22147011 {source="Europe PMC"}
xref: PMID:22251942 {source="Europe PMC"}
xref: PMID:22483686 {source="Europe PMC"}
xref: PMID:22509294 {source="Europe PMC"}
xref: Reaxys:10148626 {source="Reaxys"}
xref: Wikipedia:Somatostatin
is_a: CHEBI:24533 ! heterodetic cyclic peptide
is_a: CHEBI:25905 ! peptide hormone
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C76H104N18O19S2" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NHXLMOGPVYXJNR-ATOGVRKGSA-N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "1637.87800" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1636.71666" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N" xsd:string

[Term]
id: CHEBI:64708
name: one-carbon compound
namespace: chebi_ontology
def: "An organic molecular entity containing a single carbon atom (C1)." []
subset: 3_STAR
synonym: "one-carbon compounds" RELATED [ChEBI]
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:64709
name: organic acid
namespace: chebi_ontology
def: "Any organic molecular entity that is acidic and contains carbon in covalent linkage." []
subset: 3_STAR
synonym: "organic acids" RELATED [ChEBI]
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:64909
name: poison
namespace: chebi_ontology
def: "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." []
subset: 3_STAR
synonym: "poisonous agent" RELATED [ChEBI]
synonym: "poisonous agents" RELATED [ChEBI]
synonym: "poisonous substance" RELATED [ChEBI]
synonym: "poisonous substances" RELATED [ChEBI]
synonym: "poisons" RELATED [ChEBI]
synonym: "toxic agent" RELATED [ChEBI]
synonym: "toxic agents" RELATED [ChEBI]
synonym: "toxic substance" RELATED [ChEBI]
synonym: "toxic substances" RELATED [ChEBI]
xref: Wikipedia:Poison
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:65212
name: polysaccharide derivative
namespace: chebi_ontology
def: "A carbohydrate derivative that is any derivative of a polysaccharide." []
subset: 3_STAR
synonym: "polysaccharide derivatives" RELATED [ChEBI]
is_a: CHEBI:167559 ! glycan
is_a: CHEBI:33694 ! biomacromolecule
is_a: CHEBI:63299 ! carbohydrate derivative
relationship: has_functional_parent CHEBI:18154 ! polysaccharide

[Term]
id: CHEBI:65255
name: food preservative
namespace: chebi_ontology
def: "Substances which are added to food in order to prevent decomposition caused by  microbial growth or by undesirable chemical changes." []
subset: 3_STAR
synonym: "food preservatives" RELATED [ChEBI]
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:65256
name: antimicrobial food preservative
namespace: chebi_ontology
def: "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." []
subset: 3_STAR
synonym: "antimicrobial food preservatives" RELATED [ChEBI]
synonym: "antimicrobial preservative" RELATED [ChEBI]
synonym: "antimicrobial preservatives" RELATED [ChEBI]
is_a: CHEBI:33281 ! antimicrobial agent
is_a: CHEBI:65255 ! food preservative

[Term]
id: CHEBI:65296
name: primary ammonium ion
namespace: chebi_ontology
def: "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." []
subset: 3_STAR
synonym: "a primary amine" RELATED [UniProt]
synonym: "substituted ammonium" RELATED [ChEBI]
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: is_conjugate_acid_of CHEBI:50994 ! primary amino compound
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "H3NR" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "17.031" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.02655" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][*]" xsd:string

[Term]
id: CHEBI:67079
name: anti-inflammatory agent
namespace: chebi_ontology
def: "Any compound that has anti-inflammatory effects." []
subset: 3_STAR
synonym: "anti-inflammatory agents" RELATED [ChEBI]
synonym: "antiinflammatory agent" RELATED [ChEBI]
synonym: "antiinflammatory agents" RELATED [ChEBI]
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:72587
name: (R)-noradrenaline(1+)
namespace: chebi_ontology
def: "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3." []
subset: 3_STAR
synonym: "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium" EXACT IUPAC_NAME [IUPAC]
synonym: "(R)-noradrenaline" RELATED [UniProt]
synonym: "(R)-noradrenaline cation" RELATED [ChEBI]
synonym: "(R)-noradrenalinium cation" RELATED [ChEBI]
synonym: "(R)-noradrenalinium(1+)" RELATED [ChEBI]
xref: PDBeChem:E5E
is_a: CHEBI:166902 ! noradrenaline(1+)
relationship: has_role CHEBI:77746 ! human metabolite
relationship: is_conjugate_acid_of CHEBI:18357 ! (R)-noradrenaline
property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H12NO3" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1/t8-/m0/s1" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-QMMMGPOBSA-O" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "170.187" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "170.08117" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "C=1(C=CC(=CC1O)[C@H](C[NH3+])O)O" xsd:string

[Term]
id: CHEBI:72695
name: organic molecule
namespace: chebi_ontology
def: "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." []
subset: 3_STAR
synonym: "organic compound" RELATED [ChEBI]
synonym: "organic compounds" RELATED [ChEBI]
synonym: "organic molecules" RELATED [ChEBI]
is_a: CHEBI:25367 ! molecule
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:72813
name: exopolysaccharide
namespace: chebi_ontology
def: "A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment." []
subset: 3_STAR
synonym: "exopolysaccharides" RELATED [ChEBI]
synonym: "extracellular polymeric substance" RELATED [ChEBI]
synonym: "extracellular polymeric substances" RELATED [ChEBI]
xref: MetaCyc:Exopolysaccharides
xref: PMID:11160795 {source="Europe PMC"}
xref: PMID:11785425 {source="Europe PMC"}
xref: PMID:1444258 {source="Europe PMC"}
xref: PMID:15738217 {source="Europe PMC"}
xref: PMID:16075348 {source="Europe PMC"}
xref: PMID:17440912 {source="Europe PMC"}
xref: PMID:18097339 {source="Europe PMC"}
xref: PMID:19453747 {source="Europe PMC"}
xref: PMID:20172021 {source="Europe PMC"}
xref: PMID:20631870 {source="Europe PMC"}
xref: PMID:20718297 {source="Europe PMC"}
xref: PMID:2688547 {source="Europe PMC"}
xref: PMID:6354590 {source="Europe PMC"}
xref: Wikipedia:Exopolysaccharide
xref: Wikipedia:Extracellular_polymeric_substance
is_a: CHEBI:33694 ! biomacromolecule

[Term]
id: CHEBI:73336
name: vulnerary
namespace: chebi_ontology
def: "A drug used in treating and healing of wounds." []
subset: 3_STAR
synonym: "vulneraries" RELATED [ChEBI]
synonym: "wound-healing agent" RELATED [ChEBI]
synonym: "wound-healing agents" RELATED [ChEBI]
synonym: "wound-healing drug" RELATED [ChEBI]
synonym: "wound-healing drugs" RELATED [ChEBI]
xref: Wikipedia:Wound_healing
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:73398
name: indole skeleton
namespace: chebi_ontology
def: "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." []
subset: 3_STAR
is_a: CHEBI:73541 ! organic heterobicyclic ring
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C8N" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "110.09230" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "110.00307" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(=C(C(=C2C(=C1*)N(C(=C2*)*)*)*)*)*" xsd:string

[Term]
id: CHEBI:73541
name: organic heterobicyclic ring
namespace: chebi_ontology
def: "A bicyclic organic group that contains both carbon and hetero atoms." []
subset: 3_STAR
synonym: "organic heterobicyclic rings" RELATED [ChEBI]
is_a: CHEBI:52845 ! cyclic organic group

[Term]
id: CHEBI:75763
name: eukaryotic metabolite
namespace: chebi_ontology
def: "Any  metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." []
subset: 3_STAR
synonym: "eukaryotic metabolites" RELATED [ChEBI]
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:75767
name: animal metabolite
namespace: chebi_ontology
alt_id: CHEBI:77721
alt_id: CHEBI:77743
def: "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." []
subset: 3_STAR
synonym: "animal metabolites" RELATED [ChEBI]
is_a: CHEBI:75763 ! eukaryotic metabolite

[Term]
id: CHEBI:75768
name: mammalian metabolite
namespace: chebi_ontology
alt_id: CHEBI:77464
alt_id: CHEBI:77744
def: "Any animal metabolite produced during a metabolic reaction in mammals." []
subset: 3_STAR
synonym: "mammalian metabolites" RELATED [ChEBI]
is_a: CHEBI:75767 ! animal metabolite

[Term]
id: CHEBI:75771
name: mouse metabolite
namespace: chebi_ontology
def: "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." []
subset: 3_STAR
synonym: "mouse metabolites" RELATED [ChEBI]
synonym: "Mus musculus metabolite" RELATED [ChEBI]
synonym: "Mus musculus metabolites" RELATED [ChEBI]
is_a: CHEBI:75768 ! mammalian metabolite

[Term]
id: CHEBI:75772
name: Saccharomyces cerevisiae metabolite
namespace: chebi_ontology
alt_id: CHEBI:76949
alt_id: CHEBI:76951
def: "Any  fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." []
subset: 3_STAR
synonym: "baker's yeast metabolite" RELATED [ChEBI]
synonym: "baker's yeast metabolites" RELATED [ChEBI]
synonym: "baker's yeast secondary metabolite" RELATED [ChEBI]
synonym: "baker's yeast secondary metabolites" RELATED [ChEBI]
synonym: "S. cerevisiae metabolite" RELATED [ChEBI]
synonym: "S. cerevisiae metabolites" RELATED [ChEBI]
synonym: "S. cerevisiae secondary metabolite" RELATED [ChEBI]
synonym: "S. cerevisiae secondary metabolites" RELATED [ChEBI]
synonym: "Saccharomyces cerevisiae metabolites" RELATED [ChEBI]
synonym: "Saccharomyces cerevisiae secondary metabolites" RELATED [ChEBI]
is_a: CHEBI:76946 ! fungal metabolite

[Term]
id: CHEBI:75787
name: prokaryotic metabolite
namespace: chebi_ontology
def: "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." []
subset: 3_STAR
synonym: "prokaryotic metabolites" RELATED [ChEBI]
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:76206
name: xenobiotic metabolite
namespace: chebi_ontology
def: "Any metabolite produced by metabolism of a xenobiotic compound." []
subset: 3_STAR
synonym: "xenobiotic metabolites" RELATED [ChEBI]
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:76759
name: EC 3.* (hydrolase) inhibitor
namespace: chebi_ontology
def: "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." []
subset: 3_STAR
synonym: "EC 3.* (hydrolase) inhibitors" RELATED [ChEBI]
synonym: "EC 3.* inhibitor" RELATED [ChEBI]
synonym: "EC 3.* inhibitors" RELATED [ChEBI]
synonym: "EC 3.*.*.* inhibitor" RELATED [ChEBI]
synonym: "EC 3.*.*.* inhibitors" RELATED [ChEBI]
synonym: "hydrolase (EC 3.*) inhibitor" RELATED [ChEBI]
synonym: "hydrolase (EC 3.*) inhibitors" RELATED [ChEBI]
synonym: "hydrolase inhibitor" RELATED [ChEBI]
synonym: "hydrolase inhibitors" RELATED [ChEBI]
xref: Wikipedia:Hydrolase
is_a: CHEBI:23924 ! enzyme inhibitor

[Term]
id: CHEBI:76764
name: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
namespace: chebi_ontology
def: "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." []
subset: 3_STAR
synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor" RELATED [ChEBI]
synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors" RELATED [ChEBI]
synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor" RELATED [ChEBI]
synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors" RELATED [ChEBI]
synonym: "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors" RELATED [ChEBI]
synonym: "EC 3.5.* inhibitor" RELATED [ChEBI]
synonym: "EC 3.5.* inhibitors" RELATED [ChEBI]
is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor

[Term]
id: CHEBI:76807
name: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
namespace: chebi_ontology
def: "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." []
subset: 3_STAR
synonym: "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors" RELATED [ChEBI]
synonym: "EC 3.5.1.* inhibitor" RELATED [ChEBI]
synonym: "EC 3.5.1.* inhibitors" RELATED [ChEBI]
synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor" RELATED [ChEBI]
synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors" RELATED [ChEBI]
is_a: CHEBI:76764 ! EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor

[Term]
id: CHEBI:76924
name: plant metabolite
namespace: chebi_ontology
alt_id: CHEBI:75766
alt_id: CHEBI:76925
def: "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." []
subset: 3_STAR
synonym: "plant metabolites" RELATED [ChEBI]
synonym: "plant secondary metabolites" RELATED [ChEBI]
is_a: CHEBI:75763 ! eukaryotic metabolite

[Term]
id: CHEBI:76946
name: fungal metabolite
namespace: chebi_ontology
alt_id: CHEBI:75765
alt_id: CHEBI:76947
def: "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." []
subset: 3_STAR
synonym: "fungal metabolites" RELATED [ChEBI]
is_a: CHEBI:75763 ! eukaryotic metabolite

[Term]
id: CHEBI:76967
name: human xenobiotic metabolite
namespace: chebi_ontology
def: "Any human metabolite produced by metabolism of a xenobiotic compound in humans." []
subset: 3_STAR
synonym: "human xenobiotic metabolites" RELATED [ChEBI]
is_a: CHEBI:76206 ! xenobiotic metabolite
is_a: CHEBI:77746 ! human metabolite

[Term]
id: CHEBI:76969
name: bacterial metabolite
namespace: chebi_ontology
alt_id: CHEBI:75760
alt_id: CHEBI:76970
def: "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." []
subset: 3_STAR
is_a: CHEBI:75787 ! prokaryotic metabolite

[Term]
id: CHEBI:76971
name: Escherichia coli metabolite
namespace: chebi_ontology
def: "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." []
subset: 3_STAR
synonym: "E.coli metabolite" RELATED [ChEBI]
synonym: "E.coli metabolites" RELATED [ChEBI]
synonym: "Escherichia coli metabolites" RELATED [ChEBI]
is_a: CHEBI:76969 ! bacterial metabolite

[Term]
id: CHEBI:77746
name: human metabolite
namespace: chebi_ontology
alt_id: CHEBI:75770
alt_id: CHEBI:77123
def: "Any mammalian metabolite  produced during a metabolic reaction in humans (Homo sapiens)." []
subset: 3_STAR
synonym: "H. sapiens metabolite" RELATED [ChEBI]
synonym: "H. sapiens metabolites" RELATED [ChEBI]
synonym: "Homo sapiens metabolite" RELATED [ChEBI]
synonym: "Homo sapiens metabolites" RELATED [ChEBI]
is_a: CHEBI:75768 ! mammalian metabolite

[Term]
id: CHEBI:77941
name: EC 3.5.1.4 (amidase) inhibitor
namespace: chebi_ontology
def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." []
subset: 3_STAR
synonym: "acylamidase inhibitor" RELATED [ChEBI]
synonym: "acylamidase inhibitors" RELATED [ChEBI]
synonym: "acylamide amidohydrolase inhibitor" RELATED [ChEBI]
synonym: "acylamide amidohydrolase inhibitors" RELATED [ChEBI]
synonym: "amidase (EC 3.5.1.4) inhibitor" RELATED [ChEBI]
synonym: "amidase (EC 3.5.1.4) inhibitors" RELATED [ChEBI]
synonym: "amidase inhibitor" RELATED [ChEBI]
synonym: "amidase inhibitors" RELATED [ChEBI]
synonym: "amidohydrolase inhibitor" RELATED [ChEBI]
synonym: "amidohydrolase inhibitors" RELATED [ChEBI]
synonym: "deaminase inhibitor" RELATED [ChEBI]
synonym: "deaminase inhibitors" RELATED [ChEBI]
synonym: "EC 3.5.1.4 (amidase) inhibitors" RELATED [ChEBI]
synonym: "EC 3.5.1.4 inhibitor" RELATED [ChEBI]
synonym: "EC 3.5.1.4 inhibitors" RELATED [ChEBI]
synonym: "fatty acylamidase inhibitor" RELATED [ChEBI]
synonym: "fatty acylamidase inhibitors" RELATED [ChEBI]
synonym: "N-acetylaminohydrolase inhibitor" RELATED [ChEBI]
synonym: "N-acetylaminohydrolase inhibitors" RELATED [ChEBI]
xref: Wikipedia:Amidase
is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor

[Term]
id: CHEBI:77974
name: food packaging gas
namespace: chebi_ontology
def: "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." []
subset: 3_STAR
synonym: "food packaging gases" RELATED [ChEBI]
xref: Wikipedia:Packaging_gas
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:78295
name: food component
namespace: chebi_ontology
def: "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." []
subset: 3_STAR
synonym: "dietary component" RELATED [ChEBI]
synonym: "dietary components" RELATED [ChEBI]
synonym: "food components" RELATED [ChEBI]
is_a: CHEBI:52211 ! physiological role

[Term]
id: CHEBI:78433
name: refrigerant
namespace: chebi_ontology
def: "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." []
subset: 3_STAR
synonym: "refrigerants" RELATED [ChEBI]
xref: Wikipedia:Refrigerant
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:78608
name: alpha-amino acid zwitterion
namespace: chebi_ontology
alt_id: CHEBI:83409
def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." []
subset: 3_STAR
synonym: "an alpha-amino acid" RELATED [UniProt]
xref: MetaCyc:Alpha-Amino-Acids {source="SUBMITTER"}
is_a: CHEBI:35238 ! amino acid zwitterion
relationship: is_tautomer_of CHEBI:33704 ! alpha-amino acid
property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string
property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C([*])C([O-])=O" xsd:string

[Term]
id: CHEBI:78616
name: carbohydrates and carbohydrate derivatives
namespace: chebi_ontology
def: "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." []
subset: 3_STAR
synonym: "carbohydrates and derivatives" RELATED [ChEBI]
synonym: "carbohydrates and their derivatives" RELATED [ChEBI]
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:78675
name: fundamental metabolite
namespace: chebi_ontology
def: "Any metabolite produced by all living cells." []
subset: 3_STAR
synonym: "essential metabolite" RELATED [ChEBI]
synonym: "essential metabolites" RELATED [ChEBI]
synonym: "fundamental metabolites" RELATED [ChEBI]
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:79387
name: trivalent inorganic anion
namespace: chebi_ontology
def: "Any inorganic anion with a valency of three." []
subset: 3_STAR
synonym: "trivalent inorganic anions" RELATED [ChEBI]
is_a: CHEBI:24834 ! inorganic anion

[Term]
id: CHEBI:79388
name: divalent inorganic anion
namespace: chebi_ontology
def: "Any inorganic anion with a valency of two." []
subset: 3_STAR
synonym: "divalent inorganic anions" RELATED [ChEBI]
is_a: CHEBI:24834 ! inorganic anion

[Term]
id: CHEBI:79389
name: monovalent inorganic anion
namespace: chebi_ontology
def: "Any inorganic anion with a valency of one." []
subset: 3_STAR
synonym: "monovalent inorganic anions" RELATED [ChEBI]
is_a: CHEBI:24834 ! inorganic anion

[Term]
id: CHEBI:83039
name: crustacean metabolite
namespace: chebi_ontology
def: "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." []
subset: 3_STAR
synonym: "crustacean metabolites" RELATED [ChEBI]
is_a: CHEBI:75767 ! animal metabolite

[Term]
id: CHEBI:83056
name: Daphnia magna metabolite
namespace: chebi_ontology
def: "A Daphnia metabolite produced by the species Daphnia magna." []
subset: 3_STAR
synonym: "Daphnia magna metabolites" RELATED [ChEBI]
is_a: CHEBI:83057 ! Daphnia metabolite

[Term]
id: CHEBI:83057
name: Daphnia metabolite
namespace: chebi_ontology
def: "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" []
subset: 3_STAR
synonym: "Daphnia metabolites" RELATED [ChEBI]
xref: Wikipedia:Daphnia
is_a: CHEBI:83039 ! crustacean metabolite

[Term]
id: CHEBI:84729
name: hydroxyindoles
namespace: chebi_ontology
def: "Any member of the class of  indoles carrying at least one hydroxy group." []
subset: 3_STAR
is_a: CHEBI:24828 ! indoles
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:84735
name: algal metabolite
namespace: chebi_ontology
def: "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." []
subset: 3_STAR
synonym: "algal metabolites" RELATED [ChEBI]
is_a: CHEBI:75763 ! eukaryotic metabolite

[Term]
id: CL:0000000
name: cell
namespace: cell
def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah]
def: "A material entity that has a plasma membrane and results from cellular division." []
comment: CL and GO definitions of cell differ based on inclusive or exclusive of cell wall, etc.
comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one).
comment: We struggled with this definition. We are worried about circularity. We also considered requiring the capability of metabolism.
subset: cellxgene_subset
subset: ubprop:upper_level
xref: CALOHA:TS-2035
xref: FBbt:00007002
xref: FMA:68646
xref: GO:0005623
xref: KUPO:0000002
xref: MESH:D002477
xref: VHOG:0001533
xref: WBbt:0004017
xref: XAO:0003012
is_a: UBERON:0000061 ! anatomical structure
disjoint_from: GO:0031012 ! extracellular matrix
disjoint_from: GO:0032991 ! protein-containing complex
disjoint_from: GO:0043226 ! organelle
relationship: has_part GO:0005634 {gci_filler="PATO:0001407", gci_relation="has_characteristic"} ! nucleus
relationship: has_part GO:0005634 {gci_filler="PATO:0001908", gci_relation="has_characteristic"} ! nucleus
relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms

[Term]
id: CL:0000005
name: fibroblast neural crest derived
def: "Any fibroblast that is deriived from the neural crest." [https://orcid.org/0000-0001-5208-3432]
is_a: CL:0000057 ! fibroblast
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: CL:0000057 ! fibroblast
intersection_of: develops_from CL:0000333 ! migratory neural crest cell
relationship: develops_from CL:0000008 ! migratory cranial neural crest cell

[Term]
id: CL:0000006
name: neuronal receptor cell
subset: cellxgene_subset
synonym: "neuronal receptor cell (sensu Animalia)" EXACT []
is_a: CL:0000101 ! sensory neuron
is_a: CL:0000197 ! sensory receptor cell
intersection_of: CL:0000197 ! sensory receptor cell
intersection_of: CL:0000540 ! neuron
intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception

[Term]
id: CL:0000007
name: early embryonic cell (metazoa)
def: "A cell found in the embryo before the formation of all the gem layers is complete." [GOC:tfm]
is_a: CL:0002321 ! embryonic cell (metazoa)

[Term]
id: CL:0000008
name: migratory cranial neural crest cell
def: "Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination." [https://orcid.org/0000-0001-5208-3432, ZFA:0007091]
is_a: CL:0000333 ! migratory neural crest cell

[Term]
id: CL:0000011
name: migratory trunk neural crest cell
def: "Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination." [https://orcid.org/0000-0001-5208-3432, ZFA:0007095]
is_a: CL:0000333 ! migratory neural crest cell

[Term]
id: CL:0000014
name: germ line stem cell
def: "A stem cell that is the precursor of gametes." [doi:10.1016/j.stem.2012.05.016]
synonym: "germline stem cell" EXACT []
xref: FBbt:00004861
is_a: CL:0000034 {is_inferred="true"} ! stem cell
is_a: CL:0000039 ! germ line cell
intersection_of: CL:0000039 ! germ line cell
intersection_of: capable_of GO:0017145 ! stem cell division

[Term]
id: CL:0000015
name: male germ cell
def: "A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis." [https://orcid.org/0000-0001-5208-3432, PMID:29462262]
subset: cellxgene_subset
xref: FMA:72290
xref: MA:0002765
xref: ncithesaurus:Spermatogenic_Cell
xref: VHOG:0001531
is_a: CL:0000586 {is_inferred="true"} ! germ cell
relationship: capable_of_part_of GO:0007283 ! spermatogenesis
property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/574" xsd:string

[Term]
id: CL:0000017
name: spermatocyte
def: "A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids." [GOC:tfm, MESH:D013090]
xref: BTO:0001275
xref: CALOHA:TS-0951
xref: EMAPA:31484
xref: FBbt:00004936
xref: FMA:84049
xref: WBbt:0006799
is_a: CL:0000015 ! male germ cell
intersection_of: CL:0000015 ! male germ cell
intersection_of: capable_of GO:0048137 ! spermatocyte division
relationship: capable_of GO:0048137 ! spermatocyte division
relationship: develops_from CL:0000020 ! spermatogonium

[Term]
id: CL:0000018
name: spermatid
def: "A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa." [MESH:D013087]
synonym: "nematoblast" EXACT []
xref: BTO:0001274
xref: CALOHA:TS-0950
xref: EMAPA:31486
xref: FBbt:00004942
xref: FMA:72294
xref: WBbt:0006800
is_a: CL:0000015 ! male germ cell
is_a: CL:0000413 ! haploid cell
intersection_of: CL:0000015 ! male germ cell
intersection_of: capable_of GO:0001675 ! acrosome assembly
intersection_of: capable_of GO:0007288 ! sperm axoneme assembly
intersection_of: capable_of GO:0007289 ! spermatid nucleus differentiation
intersection_of: has_characteristic PATO:0001375 ! haploid
relationship: capable_of GO:0001675 ! acrosome assembly
relationship: capable_of GO:0007288 ! sperm axoneme assembly
relationship: capable_of GO:0007289 ! spermatid nucleus differentiation
relationship: develops_from CL:0000657 ! secondary spermatocyte

[Term]
id: CL:0000019
name: sperm
def: "A mature male germ cell that develops from a spermatid." [GOC:tfm, MESH:D013094]
subset: cellxgene_subset
synonym: "sperm cell" EXACT []
synonym: "spermatozoid" EXACT []
synonym: "spermatozoon" EXACT []
xref: BTO:0001277
xref: BTO:0002046
xref: CALOHA:TS-0949
xref: FBbt:00004954
xref: FMA:67338
xref: WBbt:0006798
is_a: CL:0000408 {is_inferred="true"} ! male gamete
relationship: develops_from CL:0000018 ! spermatid

[Term]
id: CL:0000020
name: spermatogonium
def: "An euploid male germ cell of an early stage of spermatogenesis." [MESH:D013093]
synonym: "spermatogonial cell" EXACT []
xref: BTO:0000958
xref: CALOHA:TS-2193
xref: EMAPA:31482
xref: FBbt:00004934
xref: FBbt:00004935
xref: FMA:72291
is_a: CL:0000015 ! male germ cell
intersection_of: CL:0000015 ! male germ cell
intersection_of: has_characteristic PATO:0001394 ! diploid
intersection_of: has_characteristic PATO:0001501 ! immature
relationship: has_characteristic PATO:0001394 ! diploid
relationship: has_characteristic PATO:0001501 ! immature

[Term]
id: CL:0000021
name: female germ cell
def: "Female germ cell is a germ cell that supports female gamete production." [GOC:tfm, PMID:11023867, PMID:20454446]
subset: cellxgene_subset
xref: MA:0000388
xref: ncithesaurus:Egg
xref: VHOG:0001530
is_a: CL:0000586 {is_inferred="true"} ! germ cell
intersection_of: CL:0000586 ! germ cell
intersection_of: capable_of GO:0048477 ! oogenesis
relationship: capable_of GO:0048477 ! oogenesis

[Term]
id: CL:0000022
name: female germ line stem cell
def: "A stem cell that is the precursor of female gametes." [doi:10.1016/j.stem.2012.05.016]
xref: FBbt:00004873
is_a: CL:0000014 {is_inferred="true"} ! germ line stem cell
is_a: CL:0000021 {is_inferred="true"} ! female germ cell
intersection_of: CL:0000021 ! female germ cell
intersection_of: capable_of GO:0017145 ! stem cell division

[Term]
id: CL:0000023
name: oocyte
def: "A female germ cell that has entered meiosis." [GOC:tfm, ISBN:0721662544]
subset: cellxgene_subset
synonym: "oogonium" RELATED []
xref: BTO:0000964
xref: CALOHA:TS-0711
xref: FBbt:00004886
xref: FMA:18644
xref: MESH:D009865
xref: WBbt:0006797
is_a: CL:0000021 {is_inferred="true"} ! female germ cell
is_a: CL:0000255 ! eukaryotic cell
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: participates_in GO:0007143 ! female meiotic nuclear division

[Term]
id: CL:0000024
name: oogonial cell
def: "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." [GOC:tfm, ISBN:0721662544]
subset: cellxgene_subset
xref: FMA:83673
is_a: CL:0000021 {is_inferred="true"} ! female germ cell
intersection_of: CL:0000021 ! female germ cell
intersection_of: capable_of GO:0000278 ! mitotic cell cycle
relationship: capable_of GO:0000278 ! mitotic cell cycle
relationship: develops_from CL:0000670 ! primordial germ cell

[Term]
id: CL:0000025
name: egg cell
def: "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization." [GOC:tfm, ISBN:0721662544]
synonym: "mature oocyte" EXACT []
synonym: "ovum" EXACT []
xref: BTO:0000369
xref: BTO:0003801
xref: CALOHA:TS-2191
xref: FBbt:00057012
xref: FMA:67343
xref: MESH:D010063
is_a: CL:0000675 {is_inferred="true"} ! female gamete
relationship: develops_from CL:0000023 ! oocyte
relationship: participates_in GO:0007143 ! female meiotic nuclear division
property_value: depiction "https://www.swissbiopics.org/api/image/Egg_cell.svg" xsd:anyURI

[Term]
id: CL:0000027
name: smooth muscle cell neural crest derived
def: "A smooth muscle cell derived from the neural crest." [https://orcid.org/0000-0001-5208-3432]
is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: develops_from CL:0000333 ! migratory neural crest cell
relationship: develops_from CL:0000008 ! migratory cranial neural crest cell

[Term]
id: CL:0000029
name: neural crest derived neuron
synonym: "neuron neural crest derived" EXACT []
is_a: CL:0000540 {is_inferred="true"} ! neuron
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: CL:0000540 ! neuron
intersection_of: develops_from CL:0000333 ! migratory neural crest cell
relationship: develops_from CL:0002676 ! neural crest derived neuroblast

[Term]
id: CL:0000031
name: neuroblast (sensu Vertebrata)
def: "A cell that will develop into a neuron often after a migration phase." [GOC:NV, http://en.wikipedia.org/wiki/Neuroblast]
subset: cellxgene_subset
synonym: "neuroblast" EXACT []
xref: BTO:0000930
xref: FMA:70563
is_a: CL:0000055 ! non-terminally differentiated cell
is_a: CL:0000255 ! eukaryotic cell
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>

[Term]
id: CL:0000034
name: stem cell
def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234]
comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’.
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
synonym: "animal stem cell" EXACT []
xref: CALOHA:TS-2086
xref: FMA:63368
is_a: CL:0011115 ! precursor cell
intersection_of: CL:0000000 ! cell
intersection_of: capable_of GO:0017145 ! stem cell division
relationship: capable_of GO:0017145 ! stem cell division
relationship: in_taxon NCBITaxon:33208 ! Metazoa
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000035
name: single fate stem cell
def: "A stem cell that self-renews as well as give rise to a single mature cell type." [GOC:tfm]
synonym: "unipotent stem cell" EXACT []
synonym: "unipotential stem cell" EXACT []
xref: FMA:70569
is_a: CL:0000723 ! somatic stem cell
intersection_of: CL:0000000 ! cell
intersection_of: capable_of GO:0017145 ! stem cell division
intersection_of: has_characteristic PATO:0001400 ! unipotent
relationship: has_characteristic PATO:0001400 ! unipotent

[Term]
id: CL:0000037
name: hematopoietic stem cell
def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770]
comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative.
subset: blood_and_immune_upper_slim
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "blood forming stem cell" EXACT []
synonym: "colony forming unit hematopoietic" RELATED []
synonym: "hemopoietic stem cell" EXACT []
synonym: "HSC" RELATED OMO:0003000 []
xref: BTO:0000725
xref: CALOHA:TS-0448
xref: FMA:86475
xref: MESH:D006412
xref: VHOG:0001485
is_a: CL:0000723 ! somatic stem cell
is_a: CL:0008001 ! hematopoietic precursor cell
is_a: CL:0011026 ! progenitor cell
intersection_of: CL:0000988 ! hematopoietic cell
intersection_of: capable_of GO:0002244 ! hematopoietic progenitor cell differentiation
intersection_of: capable_of GO:0048103 ! somatic stem cell division
intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse)
relationship: capable_of GO:0002244 ! hematopoietic progenitor cell differentiation
relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse)
relationship: develops_from CL:0000566 ! angioblastic mesenchymal cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000038
name: erythroid progenitor cell
def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464]
subset: blood_and_immune_upper_slim
subset: cellxgene_subset
synonym: "BFU-E" RELATED OMO:0003000 []
synonym: "blast forming unit erythroid" RELATED []
synonym: "burst forming unit erythroid" RELATED []
synonym: "CFU-E" RELATED OMO:0003000 []
synonym: "colony forming unit erythroid" RELATED []
synonym: "erythroid stem cell" RELATED []
xref: BTO:0004911
is_a: CL:0000764 ! erythroid lineage cell
is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell
relationship: develops_from CL:0000050 ! megakaryocyte-erythroid progenitor cell

[Term]
id: CL:0000039
name: germ line cell
def: "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." [GOC:tfm, ISBN:0721662544]
comment: Originally this term had some plant germ line cell children.
subset: general_cell_types_upper_slim
subset: ubprop:upper_level
is_a: CL:0000000 ! cell
relationship: capable_of GO:0022414 ! reproductive process

[Term]
id: CL:0000048
name: multi fate stem cell
def: "A stem cell that can give rise to multiple lineages of cells." [GOC:add]
synonym: "multi-fate stem cell" EXACT []
synonym: "multifate stem cell" EXACT []
synonym: "multipotent cell" EXACT []
synonym: "multipotent stem cell" EXACT []
xref: FMA:84789
is_a: CL:0000034 ! stem cell
intersection_of: CL:0000000 ! cell
intersection_of: capable_of GO:0017145 ! stem cell division
intersection_of: has_characteristic PATO:0001402 ! multipotent
relationship: has_characteristic PATO:0001402 ! multipotent

[Term]
id: CL:0000049
name: common myeloid progenitor
def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461]
comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor.  For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059).
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437]
synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437]
synonym: "CMP" RELATED OMO:0003000 [ISBN:0878932437]
synonym: "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte" RELATED [ISBN:0878932437]
synonym: "common myeloid precursor" EXACT []
synonym: "multipotential myeloid stem cell" RELATED [ISBN:0878932437]
synonym: "myeloid stem cell" RELATED [ISBN:0878932437]
synonym: "pluripotent stem cell (bone marrow)" RELATED [ISBN:0878932437]
xref: BTO:0004730
is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell
disjoint_from: CL:0000050 ! megakaryocyte-erythroid progenitor cell
disjoint_from: CL:0000051 ! common lymphoid progenitor
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000050
name: megakaryocyte-erythroid progenitor cell
def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566]
comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2.
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "CFU-EM" EXACT []
synonym: "CFU-MegE" EXACT []
synonym: "colony forming unit erythroid megakaryocyte" EXACT []
synonym: "Meg/E progenitor" EXACT []
synonym: "megakaryocyte/erythrocyte progenitor" EXACT []
synonym: "megakaryocyte/erythroid progenitor cell" EXACT []
synonym: "MEP" EXACT []
is_a: CL:0000763 ! myeloid cell
is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell
is_a: CL:0011026 ! progenitor cell
intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell
intersection_of: capable_of GO:0030218 ! erythrocyte differentiation
intersection_of: capable_of GO:0030219 ! megakaryocyte differentiation
relationship: capable_of GO:0030218 ! erythrocyte differentiation
relationship: capable_of GO:0030219 ! megakaryocyte differentiation
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000051
name: common lymphoid progenitor
def: "A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251]
comment: CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "CLP" RELATED OMO:0003000 []
synonym: "committed lymphopoietic stem cell" RELATED []
synonym: "common lymphocyte precursor" EXACT []
synonym: "common lymphocyte progenitor" EXACT []
synonym: "common lymphoid precursor" EXACT []
synonym: "early lymphocyte progenitor" RELATED []
synonym: "ELP" RELATED OMO:0003000 []
synonym: "lymphoid stem cell" RELATED []
synonym: "lymphopoietic stem cell" RELATED []
is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell
is_a: CL:0011026 ! progenitor cell
intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell
intersection_of: capable_of GO:0030098 ! lymphocyte differentiation
relationship: capable_of GO:0030098 ! lymphocyte differentiation
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000052
name: totipotent stem cell
def: "A stem cell from which all cells of the body can form." [GOC:add, GOC:tfm]
synonym: "totipotential stem cell" EXACT []
xref: FMA:84790
xref: MESH:D039901
is_a: CL:0000723 ! somatic stem cell

[Term]
id: CL:0000055
name: non-terminally differentiated cell
def: "A precursor cell with a limited number of potential fates." [SANBI:mhl]
comment: define using PATO mulit-potent or oligopotent?
subset: cellxgene_subset
synonym: "blast cell" EXACT []
xref: BTO:0000125
xref: FMA:84782
is_a: CL:0011115 ! precursor cell

[Term]
id: CL:0000056
name: myoblast
def: "A cell that is commited to differentiating into a muscle cell.  Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes.  Myoblasts also occur as transient populations of cells in muscles undergoing repair." [GOC:tfm, MESH:D032446, PMID:21849021]
xref: BTO:0000222
xref: CALOHA:TS-0650
xref: FBbt:00005083
xref: FMA:70335
xref: VHOG:0001529
is_a: CL:0000680 ! muscle precursor cell

[Term]
id: CL:0000057
name: fibroblast
def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347]
comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
xref: BTO:0000452
xref: CALOHA:TS-0362
xref: FMA:63877
xref: NCIT:C12482
xref: VHOG:0001482
is_a: CL:0002320 ! connective tissue cell
relationship: develops_from CL:0000134 ! mesenchymal stem cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000058
name: chondroblast
def: "Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell." [GO_REF:0000034, GOC:tfm, ISBN:0618947256]
synonym: "chrondoplast" EXACT []
xref: BTO:0003607
xref: FMA:66783
is_a: CL:0000055 ! non-terminally differentiated cell
is_a: CL:0002320 ! connective tissue cell
relationship: develops_from CL:0007009 ! prechondroblast
relationship: produces UBERON:0002418 ! cartilage tissue

[Term]
id: CL:0000064
name: ciliated cell
def: "A cell that has a filiform extrusion of the cell surface." [GOC:tfm]
subset: cellxgene_subset
xref: VHOG:0001532
xref: XAO:0000031
is_a: CL:0000000 ! cell
is_a: PR:000050567 ! protein-containing material entity
intersection_of: CL:0000000 ! cell
intersection_of: has_part GO:0005929 ! cilium
relationship: has_part GO:0005929 ! cilium

[Term]
id: CL:0000066
name: epithelial cell
def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847]
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
synonym: "epitheliocyte" EXACT []
xref: BTO:0000414
xref: CALOHA:TS-2026
xref: CARO:0000077
xref: FBbt:00000124
xref: FMA:66768
xref: WBbt:0003672
is_a: CL:0000000 ! cell
disjoint_from: CL:0000738 ! leukocyte
relationship: part_of UBERON:0000483 ! epithelium
property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cells.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000067
name: ciliated epithelial cell
def: "An epithelial cell that has a cilia." [GOC:tfm]
subset: cellxgene_subset
xref: FMA:70605
is_a: CL:0000064 ! ciliated cell
is_a: CL:0000066 ! epithelial cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: has_part GO:0005929 ! cilium

[Term]
id: CL:0000068
name: duct epithelial cell
def: "An epithelial cell that is part of a duct." [https://orcid.org/0000-0001-5208-3432]
subset: cellxgene_subset
is_a: CL:0000066 ! epithelial cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0000058 ! duct
relationship: part_of UBERON:0000058 ! duct

[Term]
id: CL:0000069
name: branched duct epithelial cell
is_a: CL:0000068 ! duct epithelial cell

[Term]
id: CL:0000071
name: blood vessel endothelial cell
def: "An endothelial cell that lines the vasculature." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "cuboidal endothelial cell of vascular tree" EXACT []
is_a: CL:0000076 {is_inferred="true"} ! squamous epithelial cell
is_a: CL:0002139 ! endothelial cell of vascular tree
intersection_of: CL:0000076 ! squamous epithelial cell
intersection_of: part_of UBERON:0004638 ! blood vessel endothelium
relationship: develops_from CL:0002546 ! embryonic blood vessel endothelial progenitor cell
relationship: part_of UBERON:0004638 ! blood vessel endothelium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000072
name: non-branched duct epithelial cell
is_a: CL:0000068 ! duct epithelial cell
is_a: CL:0002078 ! meso-epithelial cell

[Term]
id: CL:0000075
name: columnar/cuboidal epithelial cell
def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432]
subset: cellxgene_subset
subset: human_reference_atlas
is_a: CL:0000066 ! epithelial cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000076
name: squamous epithelial cell
subset: cellxgene_subset
xref: CALOHA:TS-1249
is_a: CL:0000066 ! epithelial cell

[Term]
id: CL:0000077
name: mesothelial cell
def: "A flattened epithelial cell of mesenchymal origin that lines the serous cavity." [GOC:tfm, ISBN:0721662544]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "mesotheliocyte" EXACT []
xref: FMA:66773
is_a: CL:0000076 ! squamous epithelial cell
is_a: CL:0000213 ! lining cell
is_a: CL:0002078 ! meso-epithelial cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000080
name: circulating cell
def: "A cell which moves among different tissues of the body, via blood, lymph, or other medium." [GOC:add]
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0000179 ! haemolymphatic fluid
relationship: part_of UBERON:0000179 ! haemolymphatic fluid

[Term]
id: CL:0000081
name: blood cell
def: "A cell found predominately in the blood." [GOC:add, GOC:tfm]
subset: cellxgene_subset
subset: general_cell_types_upper_slim
xref: FMA:62844
xref: MESH:D001773
is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell
intersection_of: CL:0000988 ! hematopoietic cell
intersection_of: capable_of GO:0008015 ! blood circulation
relationship: capable_of GO:0008015 ! blood circulation

[Term]
id: CL:0000082
name: epithelial cell of lung
def: "An epithelial cell of the lung." [https://orcid.org/0000-0001-5208-3432]
subset: cellxgene_subset
synonym: "lung epithelial cell" EXACT []
xref: BTO:0004299
is_a: CL:0000066 ! epithelial cell
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0002048 ! lung
relationship: part_of UBERON:0000115 ! lung epithelium

[Term]
id: CL:0000083
name: epithelial cell of pancreas
def: "An epithelial cell of the pancreas." [GOC:tfm]
synonym: "pancreas epithelial cell" EXACT []
synonym: "pancreatic epithelial cell" EXACT []
xref: BTO:0000028
is_a: CL:0000066 ! epithelial cell
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0001264 ! pancreas
relationship: develops_from CL:0000223 ! endodermal cell
relationship: part_of UBERON:0001264 ! pancreas

[Term]
id: CL:0000084
name: T cell
def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149]
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
synonym: "immature T cell" RELATED []
synonym: "mature T cell" RELATED []
synonym: "T lymphocyte" EXACT []
synonym: "T-cell" EXACT []
synonym: "T-lymphocyte" EXACT []
xref: BTO:0000782
xref: CALOHA:TS-1001
xref: FMA:62870
xref: MESH:D013601
xref: VHOG:0001479
is_a: CL:0000542 {is_inferred="true"} ! lymphocyte
intersection_of: CL:0000542 ! lymphocyte
intersection_of: capable_of GO:0002456 ! T cell mediated immunity
relationship: capable_of GO:0002456 ! T cell mediated immunity
relationship: develops_from CL:0000827 ! pro-T cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000095
name: neuron associated cell
subset: cellxgene_subset
is_a: CL:0002319 ! neural cell
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: develops_from CL:0000133 ! neurectodermal cell

[Term]
id: CL:0000098
name: sensory epithelial cell
def: "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells." [GOC:tfm, ISBN:0517223651, ISBN:0721662544]
comment: The term "neuroepithelial cell" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710).
synonym: "neuroepithelial cell" BROAD []
xref: BTO:0004301
is_a: CL:0000066 ! epithelial cell
is_a: CL:0000197 ! sensory receptor cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception

[Term]
id: CL:0000099
name: interneuron
def: "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions." [GOC:tfm, MESH:D007395]
subset: cellxgene_subset
subset: human_reference_atlas
xref: BTO:0003811
xref: FBbt:00005125
xref: FMA:67313
xref: WBbt:0005113
is_a: CL:0000540 ! neuron
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000100
name: motor neuron
def: "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement." [MESH:D009046, PMID:16875686]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "motoneuron" EXACT []
xref: BTO:0000312
xref: FBbt:00005123
xref: FMA:83617
xref: WBbt:0005409
is_a: CL:0000527 ! efferent neuron
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000101
name: sensory neuron
def: "Any neuron having a sensory function; an afferent neuron conveying sensory impulses." [ISBN:0721662544]
xref: BTO:0001037
xref: FBbt:00005124
xref: FMA:84649
xref: MESH:D011984
xref: WBbt:0005759
is_a: CL:0000526 ! afferent neuron
intersection_of: CL:0000540 ! neuron
intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception
relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception

[Term]
id: CL:0000107
name: autonomic neuron
def: "A neuron whose cell body is within an autonomic ganglion." [GOC:tfm]
xref: FMA:80121
is_a: CL:2000032 ! peripheral nervous system neuron
intersection_of: CL:0000540 ! neuron
intersection_of: has_soma_location UBERON:0002410 ! autonomic nervous system
relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: has_soma_location UBERON:0002410 ! autonomic nervous system

[Term]
id: CL:0000108
name: cholinergic neuron
def: "A neuron that uses acetylcholine as a vesicular neurotransmitter." [GOC:tfm]
xref: BTO:0004902
xref: FBbt:00007173
xref: FMA:84796
xref: MESH:D059329
xref: WBbt:0006840
is_a: CL:0000151 ! secretory cell
is_a: CL:0000540 ! neuron
intersection_of: CL:0000540 ! neuron
intersection_of: capable_of GO:0014055 ! acetylcholine secretion, neurotransmission
relationship: capable_of GO:0014055 ! acetylcholine secretion, neurotransmission

[Term]
id: CL:0000113
name: mononuclear phagocyte
def: "A vertebrate phagocyte with a single nucleus." [GOC:add, GOC:tfm, ISBN:0781735149]
subset: cellxgene_subset
subset: human_reference_atlas
xref: BTO:0001433
is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata)
is_a: CL:0000842 ! mononuclear cell
intersection_of: CL:0000518 ! phagocyte (sensu Vertebrata)
intersection_of: has_characteristic PATO:0001407 ! mononucleate
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000115
name: endothelial cell
def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341]
comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "endotheliocyte" EXACT []
xref: BTO:0001176
xref: CALOHA:TS-0278
xref: FMA:66772
is_a: CL:0000213 ! lining cell
is_a: CL:0002078 ! meso-epithelial cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000117
name: CNS neuron (sensu Vertebrata)
is_a: CL:0000540 ! neuron
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: part_of UBERON:0001017 ! central nervous system

[Term]
id: CL:0000125
name: glial cell
def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:D009457]
comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571
subset: cellxgene_subset
subset: general_cell_types_upper_slim
synonym: "neuroglia" RELATED []
synonym: "neuroglial cell" EXACT []
xref: BTO:0002606
xref: CALOHA:TS-0415
xref: FBbt:00005144
xref: FMA:54536
is_a: CL:0000095 ! neuron associated cell

[Term]
id: CL:0000133
name: neurectodermal cell
def: "Ectoderm destined to be nervous tissue." [GOC:tfm, ISBN:068340007X]
synonym: "neurectoderm cell" EXACT []
is_a: CL:0000221 ! ectodermal cell

[Term]
id: CL:0000134
name: mesenchymal stem cell
def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544]
comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2.
subset: cellxgene_subset
synonym: "BMSC" RELATED OMO:0003000 []
synonym: "bone marrow stromal cells" NARROW []
synonym: "CFU-F" RELATED OMO:0003000 []
synonym: "colony-forming unit-fibroblast" NARROW []
synonym: "marrow stromal cells" NARROW [PMID:11378515]
synonym: "mesenchymal precursor cell" RELATED []
synonym: "mesenchymal progenitor cells" RELATED OMO:0003004 [MESH:D044982]
synonym: "mesenchymal stem cell" RELATED []
synonym: "mesenchymal stromal cell" RELATED []
synonym: "mesenchymal stromal cells" RELATED OMO:0003004 []
synonym: "MSC" RELATED OMO:0003000 [PMID:11378515]
synonym: "stem cells, mesenchymal" RELATED OMO:0003004 [MESH:D044982]
xref: BTO:0002625
xref: BTO:0003298
xref: FMA:70546
is_a: CL:0000048 ! multi fate stem cell
is_a: CL:0002320 {is_inferred="true"} ! connective tissue cell
property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/474" xsd:string

[Term]
id: CL:0000136
name: adipocyte
def: "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." [MESH:D017667]
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
synonym: "adipose cell" EXACT []
synonym: "fat cell" EXACT []
xref: BTO:0000443
xref: CALOHA:TS-0012
xref: FMA:63880
is_a: CL:0000325 ! stuff accumulating cell
is_a: CL:0002320 ! connective tissue cell
relationship: develops_from CL:0000134 ! mesenchymal stem cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000138
name: chondrocyte
def: "Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell." [GO_REF:0000034, MESH:D019902]
subset: cellxgene_subset
synonym: "cartilage cell" EXACT []
xref: BTO:0000249
xref: CALOHA:TS-0138
xref: FMA:66782
is_a: CL:0000153 ! glycosaminoglycan secreting cell
is_a: CL:0000667 ! collagen secreting cell
relationship: develops_from CL:0000058 ! chondroblast
relationship: located_in UBERON:0002418 ! cartilage tissue

[Term]
id: CL:0000145
name: professional antigen presenting cell
def: "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." [GOC:add, ISBN:0781735149]
comment: Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.
subset: blood_and_immune_upper_slim
subset: cellxgene_subset
synonym: "APC" RELATED OMO:0003000 []
is_a: CL:0000738 ! leukocyte
intersection_of: CL:0000738 ! leukocyte
intersection_of: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
relationship: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

[Term]
id: CL:0000147
name: pigment cell
def: "A pigment cell is a cell that contains pigment granules." [GOC:tfm]
synonym: "chromatocyte" EXACT []
synonym: "chromatophore" EXACT []
xref: VHOG:0001678
is_a: CL:0000325 ! stuff accumulating cell

[Term]
id: CL:0000149
name: visual pigment cell
synonym: "pigment cell" BROAD []
is_a: CL:0000147 ! pigment cell

[Term]
id: CL:0000150
name: glandular epithelial cell
def: "A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules." [GOC:tfm]
subset: cellxgene_subset
xref: CALOHA:TS-2085
xref: FMA:86494
is_a: CL:0000066 ! epithelial cell
is_a: CL:0000151 ! secretory cell
relationship: part_of UBERON:0006799 ! glandular epithelium

[Term]
id: CL:0000151
name: secretory cell
def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544]
subset: cellxgene_subset
xref: BTO:0003659
xref: FMA:86916
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: capable_of GO:0032940 ! secretion by cell
relationship: capable_of GO:0032940 ! secretion by cell

[Term]
id: CL:0000152
name: exocrine cell
def: "A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct." [ISBN:0198547684]
subset: general_cell_types_upper_slim
xref: FMA:16014
is_a: CL:0000151 ! secretory cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: part_of UBERON:0002365 ! exocrine gland
relationship: part_of UBERON:0002365 ! exocrine gland

[Term]
id: CL:0000153
name: glycosaminoglycan secreting cell
def: "A cell that secretes glycosaminoglycans." [GOC:tfm]
synonym: "GAG secreting cell" EXACT []
synonym: "hyaluronic acid secreting cell" NARROW []
is_a: CL:0000327 ! extracellular matrix secreting cell
is_a: CL:0000447 ! carbohydrate secreting cell

[Term]
id: CL:0000154
name: protein secreting cell
is_a: CL:0000151 ! secretory cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: capable_of GO:0009306 ! protein secretion
relationship: capable_of GO:0009306 ! protein secretion

[Term]
id: CL:0000159
name: seromucus secreting cell
is_a: CL:0000151 ! secretory cell

[Term]
id: CL:0000163
name: endocrine cell
def: "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [MESH:D055098]
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
synonym: "endocrinocyte" EXACT []
xref: FMA:83809
is_a: CL:0000151 ! secretory cell
is_a: CL:0000164 {gci_relation="part_of", gci_filler="UBERON:0000945"} ! enteroendocrine cell
is_a: CL:0000164 {gci_filler="UBERON:0000160", gci_relation="part_of"} ! enteroendocrine cell
is_a: CL:0000164 {gci_filler="UBERON:0001264", gci_relation="part_of"} ! enteroendocrine cell
relationship: part_of UBERON:0000949 ! endocrine system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000164
name: enteroendocrine cell
def: "An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas." [GOC:tfm, SANBI:mhl]
subset: cellxgene_subset
xref: BTO:0003865
xref: FMA:62930
xref: MESH:D019858
is_a: CL:0000150 ! glandular epithelial cell
is_a: CL:0000163 ! endocrine cell

[Term]
id: CL:0000165
name: neuroendocrine cell
def: "A neuron that is capable of some hormone secretion in response to neuronal signals." [MESH:D055099]
comment: The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. \n\nThe modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron. {xref="https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073", xref="PMID:5342440"}
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "neurosecretory cell" RELATED []
synonym: "neurosecretory neuron" RELATED []
xref: BTO:0002691
xref: FBbt:00005130
xref: FMA:83810
is_a: CL:0000163 ! endocrine cell
is_a: CL:0000527 ! efferent neuron
is_a: CL:0000710 ! neurecto-epithelial cell
intersection_of: CL:0000540 ! neuron
intersection_of: capable_of GO:0046879 ! hormone secretion
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000167
name: peptide hormone secreting cell
is_a: CL:0000151 ! secretory cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: capable_of GO:0030072 ! peptide hormone secretion
relationship: capable_of GO:0030072 ! peptide hormone secretion

[Term]
id: CL:0000168
name: insulin secreting cell
xref: BTO:0000783
is_a: CL:0000154 ! protein secreting cell
is_a: CL:0000167 ! peptide hormone secreting cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: capable_of GO:0030073 ! insulin secretion
relationship: capable_of GO:0030073 ! insulin secretion

[Term]
id: CL:0000169
name: type B pancreatic cell
def: "A cell that secretes insulin and is located towards the center of the islets of Langerhans." [GOC:tfm, http://en.wikipedia.org/wiki/Pancreatic_b_cell, ISBN:0517223651]
comment: Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression.
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "B-cell of pancreatic islet" EXACT [FMA:70586]
synonym: "beta cell" BROAD [ZFA:0009102]
synonym: "beta cell islet" RELATED [MA:0002419]
synonym: "beta cell of pancreatic islet" EXACT [FMA:70586]
synonym: "insulin-secreting cell" EXACT [FMA:70586]
synonym: "pancreatic B cell" EXACT []
synonym: "pancreatic B-cell" EXACT [FMA:70586]
synonym: "pancreatic beta cell" EXACT [FMA:70586]
synonym: "pancreatic islet core" EXACT [MA:0002419]
synonym: "type B enteroendocrine cell" EXACT [FMA:70586]
xref: BTO:0000783
xref: EV:0200009
xref: FMA:70586
xref: MA:0002419
xref: ncithesaurus:Beta_Cell
is_a: CL:0000168 {is_inferred="true"} ! insulin secreting cell
is_a: CL:0008024 ! pancreatic endocrine cell
intersection_of: CL:0000164 ! enteroendocrine cell
intersection_of: capable_of GO:0030073 ! insulin secretion
intersection_of: part_of UBERON:0000006 ! islet of Langerhans
relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas
relationship: part_of UBERON:0000006 ! islet of Langerhans
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000170
name: glucagon secreting cell
def: "A cell that secretes glucagon." [GOC:tfm]
synonym: "glucagon-secreting cell" EXACT []
xref: FMA:84045
is_a: CL:0000167 ! peptide hormone secreting cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: capable_of GO:0070091 ! glucagon secretion
relationship: capable_of GO:0070091 ! glucagon secretion

[Term]
id: CL:0000171
name: pancreatic A cell
def: "A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon." [GOC:tfm, ISBN:0721662544]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "alpha cell of islet of Langerhans" EXACT []
synonym: "pancreatic alpha cell" EXACT []
xref: BTO:0000990
xref: FMA:70585
xref: MESH:D050416
is_a: CL:0002067 ! type A enteroendocrine cell
is_a: CL:0008024 ! pancreatic endocrine cell
intersection_of: CL:0002067 ! type A enteroendocrine cell
intersection_of: part_of UBERON:0001264 ! pancreas
relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas
relationship: part_of UBERON:0000006 ! islet of Langerhans
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000172
name: somatostatin secreting cell
is_a: CL:0000167 ! peptide hormone secreting cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: capable_of GO:0070253 ! somatostatin secretion
relationship: capable_of GO:0070253 ! somatostatin secretion

[Term]
id: CL:0000173
name: pancreatic D cell
def: "A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin." [FMA:0517223651, GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "D-cell of pancreatic islet" EXACT []
synonym: "delta cell of islet" EXACT []
synonym: "delta cell of pancreatic islet" EXACT []
synonym: "pancreatic D-cell" EXACT []
synonym: "pancreatic delta cell" EXACT []
synonym: "somatostatin-secreting pancreatic cell" EXACT []
xref: BTO:0000803
xref: FMA:70587
is_a: CL:0000502 ! type D enteroendocrine cell
is_a: CL:0008024 ! pancreatic endocrine cell
intersection_of: CL:0000502 ! type D enteroendocrine cell
intersection_of: part_of UBERON:0001264 ! pancreas
relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas
relationship: part_of UBERON:0000006 ! islet of Langerhans
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000174
name: steroid hormone secreting cell
is_a: CL:0000151 ! secretory cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: capable_of GO:0035929 ! steroid hormone secretion
relationship: capable_of GO:0035929 ! steroid hormone secretion

[Term]
id: CL:0000182
name: hepatocyte
def: "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, http://en.wikipedia.org/wiki/Hepatocyte, ISBN:0412046911, MESH:D022781, PMID:19717280]
comment: Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive.
subset: cellxgene_subset
subset: human_reference_atlas
xref: BTO:0000575
xref: CALOHA:TS-0454
xref: FMA:14515
is_a: CL:0000066 ! epithelial cell
is_a: CL:0000417 ! endopolyploid cell
is_a: UBERON:0004119 ! endoderm-derived structure
relationship: capable_of GO:0006699 ! bile acid biosynthetic process
relationship: capable_of GO:0098754 ! detoxification
relationship: develops_from CL:0005026 ! hepatoblast
relationship: part_of UBERON:0002107 ! liver
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000183
name: contractile cell
def: "A cell whose primary function is to shorten." [FB:ma]
subset: cellxgene_subset
is_a: CL:0000000 ! cell

[Term]
id: CL:0000187
name: muscle cell
def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342]
subset: cellxgene_subset
synonym: "muscle fiber" EXACT []
synonym: "myocyte" EXACT []
xref: BTO:0000888
xref: BTO:0000902
xref: CALOHA:TS-2032
xref: FBbt:00005074
xref: FMA:67328
xref: WBbt:0003675
is_a: CL:0000183 ! contractile cell
is_a: CL:0000393 ! electrically responsive cell
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: develops_from CL:0000056 ! myoblast
property_value: depiction "https://www.swissbiopics.org/api/image/Muscle_cells.svg" xsd:anyURI

[Term]
id: CL:0000188
name: cell of skeletal muscle
def: "A somatic cell located in skeletal muscle." [GOC:tfm]
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
synonym: "skeletal muscle cell" EXACT []
xref: BTO:0004392
xref: CALOHA:TS-2158
xref: FMA:9727
is_a: CL:0000000 ! cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue
relationship: part_of UBERON:0001134 ! skeletal muscle tissue
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000192
name: smooth muscle cell
def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361]
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
synonym: "myocytes, smooth muscle" EXACT [MESH:D032389]
synonym: "non-striated muscle cell" BROAD []
synonym: "SMCs" EXACT [PMID:9315361]
synonym: "smooth muscle fiber" EXACT []
xref: BTO:0004576
xref: CALOHA:TS-2159
xref: FMA:14072
is_a: CL:0008000 ! non-striated muscle cell
is_a: CL:0008007 ! visceral muscle cell
relationship: develops_from CL:0000514 ! smooth muscle myoblast
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000197
name: sensory receptor cell
def: "A cell that is capable of detection of a stimulus involved in sensory perception." []
synonym: "receptor cell" EXACT []
xref: MESH:D011984
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception
intersection_of: part_of UBERON:0001032 ! sensory system
relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception
relationship: part_of UBERON:0001032 ! sensory system

[Term]
id: CL:0000206
name: chemoreceptor cell
def: "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood." [MESH:D002628]
is_a: CL:0000197 ! sensory receptor cell
intersection_of: CL:0000197 ! sensory receptor cell
intersection_of: capable_of GO:0050907 ! detection of chemical stimulus involved in sensory perception
relationship: capable_of GO:0050907 ! detection of chemical stimulus involved in sensory perception

[Term]
id: CL:0000210
name: photoreceptor cell
def: "A cell specialized to detect and transduce light." [MESH:D010786]
subset: cellxgene_subset
xref: BTO:0001060
xref: CALOHA:TS-0868
xref: FMA:86740
is_a: CL:0000006 {is_inferred="true"} ! neuronal receptor cell
intersection_of: CL:0000540 ! neuron
intersection_of: capable_of GO:0050962 ! detection of light stimulus involved in sensory perception
relationship: capable_of GO:0050962 ! detection of light stimulus involved in sensory perception
property_value: depiction "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg" xsd:anyURI

[Term]
id: CL:0000211
name: electrically active cell
def: "A cell whose function is determined by the generation or the reception of an electric signal." [FB:ma]
is_a: CL:0000000 ! cell

[Term]
id: CL:0000213
name: lining cell
def: "A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism." [JB:jb]
synonym: "boundary cell" EXACT []
is_a: CL:0000215 ! barrier cell

[Term]
id: CL:0000214
name: synovial cell
def: "A cell located in the synovial joint." []
synonym: "synoviocyte" EXACT []
xref: CALOHA:TS-0995
is_a: CL:0000213 ! lining cell
is_a: CL:0002078 {is_inferred="true"} ! meso-epithelial cell
relationship: part_of UBERON:0002217 ! synovial joint

[Term]
id: CL:0000215
name: barrier cell
def: "A cell whose primary function is to prevent the transport of stuff across compartments." [JB:jb]
is_a: CL:0000000 ! cell

[Term]
id: CL:0000216
name: Sertoli cell
def: "A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." [MESH:D012708]
subset: cellxgene_subset
xref: BTO:0001238
xref: CALOHA:TS-0922
xref: FMA:72298
xref: VHOG:0001348
is_a: CL:0000511 ! androgen binding protein secreting cell
is_a: CL:0000630 {is_inferred="true"} ! supporting cell
is_a: CL:0002625 ! seminiferous tubule epithelial cell
intersection_of: CL:0000630 ! supporting cell
intersection_of: part_of UBERON:0001343 ! seminiferous tubule of testis

[Term]
id: CL:0000219
name: motile cell
def: "A cell that moves by its own activities." [FB:ma]
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: capable_of GO:0048870 ! cell motility
relationship: capable_of GO:0048870 ! cell motility

[Term]
id: CL:0000221
name: ectodermal cell
def: "A cell of the outer of the three germ layers of the embryo." [MESH:D004475]
synonym: "ectoderm cell" EXACT []
xref: FMA:72549
is_a: CL:0002321 ! embryonic cell (metazoa)
relationship: part_of UBERON:0000924 ! ectoderm

[Term]
id: CL:0000222
name: mesodermal cell
def: "A cell of the middle germ layer of the embryo." [MESH:D008648]
subset: cellxgene_subset
synonym: "mesoblast" EXACT []
synonym: "mesoderm cell" EXACT []
xref: FMA:72554
is_a: CL:0002321 ! embryonic cell (metazoa)
relationship: part_of UBERON:0000926 ! mesoderm

[Term]
id: CL:0000223
name: endodermal cell
def: "A cell of the inner of the three germ layers of the embryo." [MESH:D004707]
synonym: "endoderm cell" EXACT []
xref: FMA:72555
is_a: CL:0002321 ! embryonic cell (metazoa)
relationship: part_of UBERON:0000925 ! endoderm

[Term]
id: CL:0000225
name: anucleate cell
def: "A cell that lacks a nucleus." [FB:ma]
synonym: "non-nucleated cell" EXACT []
xref: FMA:68647
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: has_characteristic PATO:0001405 ! anucleate
disjoint_from: CL:0002242 ! nucleate cell
relationship: has_characteristic PATO:0001405 ! anucleate

[Term]
id: CL:0000226
name: single nucleate cell
def: "A cell with a single nucleus." [FB:ma, GOC:tfm]
is_a: CL:0002242 ! nucleate cell
intersection_of: CL:0000000 ! cell
intersection_of: has_characteristic PATO:0001407 ! mononucleate
relationship: has_characteristic PATO:0001407 ! mononucleate

[Term]
id: CL:0000227
name: binucleate cell
is_a: CL:0000228 ! multinucleate cell
intersection_of: CL:0000000 ! cell
intersection_of: has_characteristic PATO:0001406 ! binucleate
relationship: has_characteristic PATO:0001406 ! binucleate

[Term]
id: CL:0000228
name: multinucleate cell
def: "A cell with more than one nucleus." [FB:ma]
synonym: "syncitium" EXACT []
synonym: "syncytial cell" EXACT []
synonym: "syncytium" EXACT []
xref: AEO:0000203
xref: WBbt:0008074
is_a: CL:0002242 ! nucleate cell
intersection_of: CL:0000000 ! cell
intersection_of: has_characteristic PATO:0001908 ! multinucleate
relationship: has_characteristic PATO:0001908 ! multinucleate

[Term]
id: CL:0000232
name: erythrocyte
def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912]
subset: blood_and_immune_upper_slim
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "RBC" EXACT []
synonym: "red blood cell" EXACT []
xref: BTO:0000424
xref: CALOHA:TS-0290
xref: FMA:81100
is_a: CL:0000081 ! blood cell
is_a: CL:0000329 ! oxygen accumulating cell
is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell
intersection_of: CL:0000764 ! erythroid lineage cell
intersection_of: capable_of GO:0008015 ! blood circulation
intersection_of: capable_of GO:0015671 ! oxygen transport
intersection_of: CL:4030045 GO:0005840 ! lacks_part ribosome
intersection_of: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1
intersection_of: has_characteristic PATO:0002039 ! biconcave
relationship: CL:4030045 GO:0005840 ! lacks_part ribosome
relationship: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1
relationship: develops_from CL:0000558 ! reticulocyte
relationship: has_characteristic PATO:0002039 ! biconcave
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000234
name: phagocyte
def: "Any cell capable of ingesting particulate matter via phagocytosis." [GOC:add, ISBN:0721601464]
subset: cellxgene_subset
xref: BTO:0001044
xref: FMA:83806
xref: MESH:D010586
is_a: CL:0000219 ! motile cell
is_a: CL:0000325 ! stuff accumulating cell
is_a: CL:0000473 ! defensive cell
intersection_of: CL:0000000 ! cell
intersection_of: capable_of GO:0006909 ! phagocytosis
relationship: capable_of GO:0006909 ! phagocytosis

[Term]
id: CL:0000255
name: eukaryotic cell
subset: cellxgene_subset
xref: MESH:D005057
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: only_in_taxon NCBITaxon:2759 ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota

[Term]
id: CL:0000257
name: Eumycetozoan cell
is_a: CL:0000255 ! eukaryotic cell
intersection_of: CL:0000000 ! cell
intersection_of: only_in_taxon NCBITaxon:142796 ! Eumycetozoa
relationship: only_in_taxon NCBITaxon:142796 ! Eumycetozoa

[Term]
id: CL:0000287
name: eye photoreceptor cell
subset: cellxgene_subset
subset: eye_upper_slim
subset: human_reference_atlas
is_a: CL:0000210 ! photoreceptor cell
intersection_of: CL:0000210 ! photoreceptor cell
intersection_of: part_of UBERON:0000970 ! eye
relationship: part_of UBERON:0000970 ! eye
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000293
name: structural cell
def: "A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism." [TAIR:sr]
is_a: CL:0000000 ! cell

[Term]
id: CL:0000300
name: gamete
def: "A mature sexual reproductive cell having a single set of unpaired chromosomes." [GOC:tfm, ISBN:0721662544]
synonym: "haploid germ cell" RELATED []
synonym: "haploid nucleated cell" EXACT []
xref: CALOHA:TS-0395
xref: FBbt:00005412
xref: FMA:18649
is_a: CL:0000413 ! haploid cell
is_a: CL:0000586 {is_inferred="true"} ! germ cell
intersection_of: CL:0000586 ! germ cell
intersection_of: capable_of GO:0009566 ! fertilization
intersection_of: has_characteristic PATO:0001375 ! haploid
relationship: capable_of GO:0009566 ! fertilization

[Term]
id: CL:0000306
name: crystallin accumulating cell
subset: eye_upper_slim
synonym: "lens cell" EXACT []
is_a: CL:0000325 ! stuff accumulating cell

[Term]
id: CL:0000313
name: serous secreting cell
def: "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid." [GOC:tfm, ISBN:0517223651, ISBN:0721662544]
subset: cellxgene_subset
synonym: "serous cell" EXACT []
xref: BTO:0003687
xref: FMA:62511
is_a: CL:0000159 ! seromucus secreting cell

[Term]
id: CL:0000319
name: mucus secreting cell
subset: cellxgene_subset
synonym: "mucous cell" EXACT []
xref: BTO:0003689
is_a: CL:0000159 ! seromucus secreting cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: capable_of GO:0070254 ! mucus secretion
relationship: capable_of GO:0070254 ! mucus secretion

[Term]
id: CL:0000325
name: stuff accumulating cell
def: "A cell that is specialised to accumulate a particular substance(s)." [FB:ma]
subset: ubprop:upper_level
is_a: CL:0000000 ! cell

[Term]
id: CL:0000327
name: extracellular matrix secreting cell
is_a: CL:0000499 ! stromal cell

[Term]
id: CL:0000329
name: oxygen accumulating cell
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: capable_of GO:0015671 ! oxygen transport
relationship: capable_of GO:0015671 ! oxygen transport

[Term]
id: CL:0000333
name: migratory neural crest cell
def: "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body." [doi:10.1016/j.stem.2015.02.017]
xref: FMA:86667
is_a: CL:0000219 ! motile cell
is_a: CL:0011012 ! neural crest cell
is_a: CL:0011026 ! progenitor cell
is_a: UBERON:0010313 ! neural crest-derived structure
relationship: develops_from CL:0007004 ! premigratory neural crest cell

[Term]
id: CL:0000335
name: mesenchyme condensation cell
def: "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors." [GOC:tfm, PMID:5025404]
is_a: CL:0008019 ! mesenchymal cell

[Term]
id: CL:0000347
name: scleral cell
def: "A cell of the sclera of the eye." [GOC:add]
subset: eye_upper_slim
is_a: CL:0000293 ! structural cell
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: CL:0000293 ! structural cell
intersection_of: part_of UBERON:0001773 ! sclera
relationship: develops_from CL:0000008 ! migratory cranial neural crest cell
relationship: part_of UBERON:0001773 ! sclera

[Term]
id: CL:0000348
name: choroidal cell of the eye
def: "A structural cell that is part of optic choroid." [GOC:add]
subset: eye_upper_slim
is_a: CL:0000293 ! structural cell
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: CL:0000293 ! structural cell
intersection_of: part_of UBERON:0001776 ! optic choroid
relationship: develops_from CL:0000008 ! migratory cranial neural crest cell
relationship: part_of UBERON:0001776 ! optic choroid

[Term]
id: CL:0000349
name: extraembryonic cell
subset: general_cell_types_upper_slim
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0000478 ! extraembryonic structure
relationship: part_of UBERON:0000478 ! extraembryonic structure

[Term]
id: CL:0000351
name: trophoblast cell
def: "A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface." [GOC:tfm, MESH:D014327]
synonym: "trophoblastic cell" EXACT []
xref: FMA:83028
is_a: CL:0000349 {is_inferred="true"} ! extraembryonic cell
relationship: part_of UBERON:0000358 ! blastocyst

[Term]
id: CL:0000352
name: epiblast cell
def: "A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation." [GOC:tfm, ISBN:0618947256]
is_a: CL:0000052 ! totipotent stem cell

[Term]
id: CL:0000353
name: blastoderm cell
def: "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)." [MESH:D001756]
synonym: "blastomere" EXACT []
xref: BTO:0001473
xref: FMA:72551
is_a: CL:0000007 ! early embryonic cell (metazoa)

[Term]
id: CL:0000354
name: blastemal cell
synonym: "blastema cell" EXACT []
xref: ncithesaurus:Blastemal_Cell
is_a: CL:0000048 ! multi fate stem cell

[Term]
id: CL:0000355
name: multi-potent skeletal muscle stem cell
def: "A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell." [PMID:18282570]
comment: Multi-potency demonstrated ex vivo.  At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo.
xref: FMA:86767
is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell
is_a: CL:0000188 ! cell of skeletal muscle
intersection_of: CL:0000048 ! multi fate stem cell
intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue

[Term]
id: CL:0000358
name: sphincter associated smooth muscle cell
def: "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning." [GOC:cjm]
is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0004590 ! sphincter muscle
relationship: part_of UBERON:0004590 ! sphincter muscle

[Term]
id: CL:0000359
name: vascular associated smooth muscle cell
def: "A smooth muscle cell associated with the vasculature." [GOC:dsd, GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "vascular smooth muscle cell" EXACT []
synonym: "VSMC" EXACT []
is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell
is_a: CL:4033054 ! perivascular cell
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0002049 ! vasculature
relationship: part_of UBERON:0002049 ! vasculature
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000362
name: epidermal cell
def: "An epithelial cell of the integument (the outer layer of an organism)." [Flybase:dsj, MA:ma]
subset: cellxgene_subset
synonym: "cell of epidermis" EXACT [FMA:62411]
synonym: "epithelial cell of skin" NARROW [FMA:62411]
xref: BTO:0001470
xref: CALOHA:TS-0283
xref: FMA:62411
xref: MESH:D000078404
is_a: CL:0002159 ! general ecto-epithelial cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0007376 ! outer epithelium
relationship: part_of UBERON:0007376 ! outer epithelium

[Term]
id: CL:0000365
name: animal zygote
def: "Diploid cell produced by the fusion of sperm cell nucleus and egg cell." [ISBN:0471245208]
synonym: "zygote" BROAD []
xref: BTO:0000854
xref: EHDAA2:0004546
xref: FMA:72395
is_a: CL:0000007 ! early embryonic cell (metazoa)
is_a: CL:0000255 ! eukaryotic cell
is_a: CL:0010017 ! zygote
intersection_of: CL:0010017 ! zygote
intersection_of: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa

[Term]
id: CL:0000393
name: electrically responsive cell
def: "A cell whose function is determined by its response to an electric signal." [FB:ma]
is_a: CL:0000211 ! electrically active cell

[Term]
id: CL:0000397
name: ganglion interneuron
subset: cellxgene_subset
is_a: CL:0000099 {is_inferred="true"} ! interneuron
intersection_of: CL:0000099 ! interneuron
intersection_of: has_soma_location UBERON:0000045 ! ganglion
relationship: has_soma_location UBERON:0000045 ! ganglion

[Term]
id: CL:0000402
name: CNS interneuron
def: "An interneuron that has its cell body in a central nervous system." [doi:10.1016/B978-0-12-817424-1.00001-X]
comment: Interneurons are commonly described as being only found in the central nervous system. However, in CL we define 'interneuron' more broadly as any neuron that is neither a motor neuron nor a sensory neuron, regardless of its location, so we need this term to refer strictly to interneurons of the central nervous system.
subset: human_reference_atlas
is_a: CL:0000099 ! interneuron
is_a: CL:2000029 ! central nervous system neuron
intersection_of: CL:0000099 ! interneuron
intersection_of: has_soma_location UBERON:0001017 ! central nervous system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000404
name: electrically signaling cell
def: "A cell that initiates an electrical signal and passes that signal to another cell." [FB:ma]
is_a: CL:0000211 ! electrically active cell

[Term]
id: CL:0000408
name: male gamete
xref: BTO:0001277
xref: CALOHA:TS-0949
is_a: CL:0000015 {is_inferred="true"} ! male germ cell
is_a: CL:0000300 {is_inferred="true"} ! gamete
intersection_of: CL:0000015 ! male germ cell
intersection_of: capable_of GO:0009566 ! fertilization
intersection_of: has_characteristic PATO:0001375 ! haploid

[Term]
id: CL:0000412
name: polyploid cell
def: "A cell that contains more than two haploid sets of chromosomes." [FB:ma, https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy, PMID:32646579]
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: has_characteristic PATO:0001377 ! polyploid
relationship: has_characteristic PATO:0001377 ! polyploid

[Term]
id: CL:0000413
name: haploid cell
def: "A cell whose nucleus contains a single haploid genome." [FB:ma, GOC:tfm]
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: has_characteristic PATO:0001375 ! haploid
relationship: has_characteristic PATO:0001375 ! haploid

[Term]
id: CL:0000417
name: endopolyploid cell
is_a: CL:0000412 ! polyploid cell

[Term]
id: CL:0000447
name: carbohydrate secreting cell
is_a: CL:0000151 ! secretory cell

[Term]
id: CL:0000451
name: dendritic cell
def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149]
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
synonym: "interdigitating cell" RELATED []
synonym: "veiled cell" RELATED []
xref: BTO:0002042
xref: CALOHA:TS-0194
xref: FMA:83036
xref: MESH:D003713
is_a: CL:0000113 ! mononuclear phagocyte
is_a: CL:0000145 ! professional antigen presenting cell
is_a: PR:000050567 ! protein-containing material entity
intersection_of: CL:0000738 ! leukocyte
intersection_of: capable_of GO:0001816 ! cytokine production
intersection_of: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
intersection_of: capable_of GO:0019882 ! antigen processing and presentation
intersection_of: capable_of GO:0045580 ! regulation of T cell differentiation
intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule
intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
intersection_of: has_characteristic PATO:0001407 ! mononucleate
intersection_of: has_part GO:0042613 ! MHC class II protein complex
disjoint_from: CL:0000542 ! lymphocyte
relationship: capable_of GO:0001816 ! cytokine production
relationship: capable_of GO:0045580 ! regulation of T cell differentiation
relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule
relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
relationship: has_part GO:0042613 ! MHC class II protein complex
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000457
name: biogenic amine secreting cell
is_a: CL:0000151 ! secretory cell

[Term]
id: CL:0000458
name: serotonin secreting cell
def: "A cell type that secretes 5-Hydroxytryptamine (serotonin)." [GOC:tfm, PMID:19630576]
synonym: "5-HT secreting cell" EXACT []
synonym: "5-Hydroxytryptamine secreting cell" EXACT []
is_a: CL:0000457 ! biogenic amine secreting cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: capable_of GO:0001820 ! serotonin secretion
relationship: capable_of GO:0001820 ! serotonin secretion

[Term]
id: CL:0000459
name: noradrenergic cell
def: "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme." [GOC:tfm, ISBN:068340007X]
synonym: "noradrenaline secreting cell" EXACT []
synonym: "norepinephrin secreting cell" EXACT []
synonym: "norepinephrine secreting cell" EXACT []
is_a: CL:0000457 ! biogenic amine secreting cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: capable_of GO:0048243 ! norepinephrine secretion
relationship: capable_of GO:0048243 ! norepinephrine secretion

[Term]
id: CL:0000473
name: defensive cell
def: "A cell whose primary function is to protect the organism." [JB:jb]
is_a: CL:0000000 ! cell

[Term]
id: CL:0000488
name: visible light photoreceptor cell
def: "A photoreceptor cell that detects visible light." [GOC:tfm]
is_a: CL:0000210 ! photoreceptor cell
intersection_of: CL:0000210 ! photoreceptor cell
intersection_of: capable_of GO:0009584 ! detection of visible light
relationship: capable_of GO:0009584 ! detection of visible light

[Term]
id: CL:0000499
name: stromal cell
def: "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere." [GOC:tfm, MESH:D017154]
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
xref: BTO:0002064
xref: FMA:83624
is_a: CL:0002320 ! connective tissue cell
relationship: develops_from CL:0000134 ! mesenchymal stem cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000502
name: type D enteroendocrine cell
def: "A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin." [MESH:D019864]
subset: cellxgene_subset
synonym: "D cell" EXACT []
xref: FMA:62935
is_a: CL:0000164 ! enteroendocrine cell
is_a: CL:0000172 ! somatostatin secreting cell

[Term]
id: CL:0000506
name: enkephalin secreting cell
def: "An endorphine cell that secretes enkephalin." [GO:tfm]
is_a: CL:0000507 ! endorphin secreting cell

[Term]
id: CL:0000507
name: endorphin secreting cell
def: "A peptide hormone secreting cell that secretes endorphin." [GO:tfm]
is_a: CL:0000167 ! peptide hormone secreting cell

[Term]
id: CL:0000508
name: type G enteroendocrine cell
def: "An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli." [GOC:tfm, ISBN:0517223651, MESH:D019863]
subset: cellxgene_subset
synonym: "G cell" EXACT []
xref: BTO:0004108
xref: FMA:67609
is_a: CL:0000164 ! enteroendocrine cell
is_a: CL:0000506 ! enkephalin secreting cell
is_a: CL:0000509 ! gastrin secreting cell
is_a: CL:0002180 ! mucous cell of stomach
relationship: part_of UBERON:0004997 ! mucosa of pyloric antrum

[Term]
id: CL:0000509
name: gastrin secreting cell
def: "A peptide hormone secreting cell that secretes gastrin." [GO:tfm]
subset: human_reference_atlas
is_a: CL:0000167 ! peptide hormone secreting cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000511
name: androgen binding protein secreting cell
def: "A peptide hormone secreting cell that secretes androgen binding protein." [GO:tfm]
is_a: CL:0000154 ! protein secreting cell

[Term]
id: CL:0000513
name: cardiac muscle myoblast
def: "A precursor cell destined to differentiate into cardiac muscle cell." [GOC:tfm, MESH:D032386]
subset: cellxgene_subset
synonym: "cardiac muscle progenitor cell" EXACT []
synonym: "cardiomyocyte progenitor cell" EXACT []
xref: FMA:84797
is_a: CL:0002494 ! cardiocyte
is_a: CL:0010021 ! cardiac myoblast
intersection_of: CL:0000056 ! myoblast
intersection_of: develops_into CL:0000746 ! cardiac muscle cell
intersection_of: part_of UBERON:0001133 ! cardiac muscle tissue
relationship: part_of UBERON:0001133 ! cardiac muscle tissue

[Term]
id: CL:0000514
name: smooth muscle myoblast
def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390]
subset: cellxgene_subset
synonym: "myoblast, smooth muscle" EXACT [MESH:D032390]
synonym: "satellite cell" RELATED []
xref: FMA:84798
is_a: CL:0000056 ! myoblast
intersection_of: CL:0000056 ! myoblast
intersection_of: develops_into CL:0000192 ! smooth muscle cell
relationship: develops_into CL:0000192 ! smooth muscle cell

[Term]
id: CL:0000515
name: skeletal muscle myoblast
def: "A myoblast that differentiates into skeletal muscle fibers." [SANBI:mhl]
synonym: "skeletal myoblast" EXACT []
xref: FMA:84799
is_a: CL:0000056 ! myoblast
is_a: CL:0011026 ! progenitor cell
intersection_of: CL:0000056 ! myoblast
intersection_of: develops_into CL:0008002 ! skeletal muscle fiber
relationship: develops_from CL:0000355 ! multi-potent skeletal muscle stem cell
relationship: develops_into CL:0008002 ! skeletal muscle fiber

[Term]
id: CL:0000518
name: phagocyte (sensu Vertebrata)
def: "A phagocyte in vertebrates that is able to phagocytosis." [GOC:tfm]
is_a: CL:0000234 ! phagocyte
is_a: CL:0000255 ! eukaryotic cell
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>

[Term]
id: CL:0000521
name: fungal cell
is_a: CL:0000255 ! eukaryotic cell
intersection_of: CL:0000000 ! cell
intersection_of: only_in_taxon NCBITaxon:4751 ! Fungi
relationship: only_in_taxon NCBITaxon:4751 ! Fungi

[Term]
id: CL:0000525
name: syncytiotrophoblast cell
def: "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy." [GOC:tfm, ISBN:0323052908]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "plasmidotrophoblast cell" RELATED []
synonym: "syncytial trophoblast cell" EXACT [PMID:11787150]
synonym: "syncytiotrophoblastic cell" EXACT [PMID:21733368]
synonym: "syntrophoblast cell" RELATED []
xref: FMA:83043
is_a: CL:0000228 ! multinucleate cell
is_a: CL:0000351 ! trophoblast cell
intersection_of: CL:0000351 ! trophoblast cell
intersection_of: has_characteristic PATO:0001908 ! multinucleate
relationship: part_of UBERON:0000371 ! syncytiotrophoblast
property_value: RO:0002175 NCBITaxon:9606
property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/2100" xsd:string

[Term]
id: CL:0000526
name: afferent neuron
def: "A neuron which conveys sensory information centrally from the periphery." [GOC:tfm, MESH:D009475]
subset: human_reference_atlas
synonym: "input neuron" EXACT []
xref: FMA:87653
is_a: CL:0000540 ! neuron
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000527
name: efferent neuron
def: "A neuron which sends impulses peripherally to activate muscles or secretory cells." [MESH:D009476]
synonym: "output neuron" EXACT []
is_a: CL:0000540 ! neuron

[Term]
id: CL:0000540
name: neuron
def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474]
comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma.
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
synonym: "nerve cell" EXACT []
xref: BTO:0000938
xref: CALOHA:TS-0683
xref: FBbt:00005106
xref: FMA:54527
xref: VHOG:0001483
xref: WBbt:0003679
is_a: CL:0000393 ! electrically responsive cell
is_a: CL:0000404 ! electrically signaling cell
is_a: CL:0002319 ! neural cell
relationship: capable_of GO:0019226 ! transmission of nerve impulse
relationship: develops_from CL:0000031 {gci_relation="in_taxon", gci_filler="NCBITaxon:7742", xref="https://github.com/obophenotype/cell-ontology/issues/757"} ! neuroblast (sensu Vertebrata)
property_value: depiction "https://www.swissbiopics.org/api/image/Neuron_cells.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000542
name: lymphocyte
def: "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [GOC:add, ISBN:0683073696, ISBN:0781735149]
comment: Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)
subset: cellxgene_subset
subset: human_reference_atlas
xref: BTO:0000775
xref: CALOHA:TS-0583
xref: FMA:62863
xref: MESH:D008214
xref: VHOG:0001535
is_a: CL:0000842 ! mononuclear cell
is_a: PR:000050567 ! protein-containing material entity
intersection_of: CL:0000738 ! leukocyte
intersection_of: has_characteristic PATO:0001407 ! mononucleate
intersection_of: has_characteristic PATO:0040072 ! high nuclear/cytoplasmic ratio
intersection_of: has_part CL:0017500 ! neutrophillic cytoplasm
intersection_of: has_part GO:0000792 ! heterochromatin
disjoint_from: CL:0000766 ! myeloid leukocyte
relationship: develops_from CL:0000051 ! common lymphoid progenitor
relationship: has_characteristic PATO:0040072 ! high nuclear/cytoplasmic ratio
relationship: has_part CL:0017500 ! neutrophillic cytoplasm
relationship: has_part GO:0000792 ! heterochromatin
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000547
name: proerythroblast
def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021]
subset: blood_and_immune_upper_slim
subset: cellxgene_subset
synonym: "pronormoblast" RELATED []
synonym: "rubriblast" EXACT [ISBN:0721601464]
xref: FMA:83518
is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell
is_a: CL:0002242 ! nucleate cell
is_a: PR:000050567 ! protein-containing material entity
intersection_of: CL:0000764 ! erythroid lineage cell
intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
intersection_of: has_characteristic PATO:0002505 ! nucleated
intersection_of: has_characteristic PATO:0040072 ! high nuclear/cytoplasmic ratio
intersection_of: has_part CL:0017503 ! basophilic cytoplasm
intersection_of: has_part GO:0005730 ! nucleolus
intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1
relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
relationship: develops_from CL:0000038 ! erythroid progenitor cell
relationship: has_characteristic PATO:0040072 ! high nuclear/cytoplasmic ratio
relationship: has_part CL:0017503 ! basophilic cytoplasm
relationship: has_part GO:0005730 ! nucleolus
relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1

[Term]
id: CL:0000549
name: basophilic erythroblast
def: "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers." [GOC:tfm, ISBN:0721601464]
synonym: "basophilic normoblast" EXACT [ISBN:0721601464]
synonym: "early erythroblast" EXACT [ISBN:0721601464]
synonym: "early normoblast" EXACT [ISBN:0721601464]
synonym: "prorubricyte" EXACT [ISBN:0721601464]
xref: FMA:83505
is_a: CL:0000765 {is_inferred="true"} ! erythroblast
is_a: PR:000050567 ! protein-containing material entity
intersection_of: CL:0000765 ! erythroblast
intersection_of: has_part CL:0017503 ! basophilic cytoplasm
intersection_of: has_part GO:0000792 ! heterochromatin
intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1
relationship: has_part CL:0017503 ! basophilic cytoplasm
relationship: has_part GO:0000792 ! heterochromatin
relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1

[Term]
id: CL:0000550
name: polychromatophilic erythroblast
def: "A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers." [ISBN:0721601464]
synonym: "intermediate erythroblast" EXACT [ISBN:0721601464]
synonym: "intermediate normoblast" EXACT [ISBN:0721601464]
synonym: "polychromatic erythroblast" EXACT [ISBN:0721601464]
synonym: "polychromatic normoblast" EXACT [ISBN:0721601464]
synonym: "polychromatophilic normoblast" EXACT [ISBN:0721601464]
synonym: "rubricyte" EXACT [ISBN:0721601464]
xref: FMA:83506
is_a: CL:0000765 {is_inferred="true"} ! erythroblast
is_a: PR:000050567 ! protein-containing material entity
intersection_of: CL:0000765 ! erythroblast
intersection_of: has_part CL:0017504 ! polychromatophilic cytoplasm
intersection_of: has_part GO:0000792 ! heterochromatin
intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1
relationship: develops_from CL:0000549 ! basophilic erythroblast
relationship: has_part CL:0017504 ! polychromatophilic cytoplasm
relationship: has_part GO:0000792 ! heterochromatin
relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1

[Term]
id: CL:0000552
name: orthochromatic erythroblast
def: "The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated." [ISBN:0721601464]
synonym: "acidophilic erythroblast" EXACT [ISBN:0721601464]
synonym: "eosinophilic erythroblast" EXACT [ISBN:0721601464]
synonym: "late erythoblast" EXACT []
synonym: "orthochromatic normoblast" EXACT [ISBN:0721601464]
synonym: "pyknotic eto enrythroblast" EXACT [ISBN:0721601464]
xref: FMA:84646
is_a: CL:0000765 {is_inferred="true"} ! erythroblast
intersection_of: CL:0000765 ! erythroblast
intersection_of: has_part CL:0017502 ! acidophilic cytoplasm
intersection_of: participates_in GO:0030263 ! apoptotic chromosome condensation
relationship: develops_from CL:0000550 ! polychromatophilic erythroblast
relationship: has_part CL:0017502 ! acidophilic cytoplasm
relationship: participates_in GO:0030263 ! apoptotic chromosome condensation

[Term]
id: CL:0000553
name: megakaryocyte progenitor cell
def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464]
comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498]
synonym: "colony-forming unit-megakaryocyte" EXACT []
synonym: "Meg-CFC" EXACT [PMCID:PMC1794060]
synonym: "megacaryoblast" EXACT []
synonym: "megacaryocyte progenitor cell" EXACT []
synonym: "megakaryoblast" EXACT []
synonym: "megakaryocytic progenitor cell" EXACT [PMID:12482498]
synonym: "MkP" EXACT [PMID:21116988]
synonym: "promegacaryocyte" RELATED []
synonym: "promegakaryocyte" RELATED []
xref: BTO:0001164
xref: CALOHA:TS-0610
xref: FMA:84235
xref: MESH:D055016
is_a: CL:0000763 ! myeloid cell
is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell
intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell
intersection_of: capable_of GO:0007113 ! endomitotic cell cycle
intersection_of: capable_of GO:0030219 ! megakaryocyte differentiation
intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse)
relationship: capable_of GO:0007113 ! endomitotic cell cycle
relationship: capable_of GO:0030219 ! megakaryocyte differentiation
relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse)
relationship: develops_from CL:0000050 ! megakaryocyte-erythroid progenitor cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000556
name: megakaryocyte
def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076]
comment: Megakaryocytes are reportedly CD181-positive and CD182-positive.
subset: blood_and_immune_upper_slim
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "megacaryocyte" EXACT []
synonym: "megalocaryocyte" EXACT []
synonym: "megalokaryocyte" EXACT []
xref: BTO:0000843
xref: CALOHA:TS-0611
xref: FMA:83555
is_a: CL:0000763 {is_inferred="true"} ! myeloid cell
disjoint_from: CL:0000764 ! erythroid lineage cell
relationship: develops_from CL:0000553 ! megakaryocyte progenitor cell
relationship: has_characteristic PATO:0001393 ! euploid
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000558
name: reticulocyte
def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622]
subset: blood_and_immune_upper_slim
subset: cellxgene_subset
xref: BTO:0001173
xref: CALOHA:TS-0864
xref: MESH:D012156
is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell
is_a: PR:000050567 ! protein-containing material entity
intersection_of: CL:0000764 ! erythroid lineage cell
intersection_of: capable_of GO:0071971 ! extracellular exosome assembly
intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1
relationship: capable_of GO:0071971 ! extracellular exosome assembly
relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
relationship: develops_from CL:0000552 ! orthochromatic erythroblast
relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1

[Term]
id: CL:0000562
name: nucleate erythrocyte
def: "An erythrocyte having a nucleus." [GOC:add, GOc:tfm]
synonym: "RBC" BROAD []
synonym: "red blood cell" BROAD []
is_a: CL:0000232 {is_inferred="true"} ! erythrocyte
is_a: CL:0002242 ! nucleate cell
intersection_of: CL:0000232 ! erythrocyte
intersection_of: has_characteristic PATO:0002505 ! nucleated
relationship: develops_from CL:0002421 ! nucleated reticulocyte

[Term]
id: CL:0000566
name: angioblastic mesenchymal cell
def: "A mesenchymal stem cell capable of developing into blood vessel endothelium." [GOC:dsd, GOC:tfm, PMID:12768659]
comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive.
synonym: "angioblast" EXACT []
synonym: "chondroplast" EXACT []
is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell
is_a: CL:0011026 ! progenitor cell
is_a: PR:000050567 ! protein-containing material entity
intersection_of: CL:0000134 ! mesenchymal stem cell
intersection_of: has_plasma_membrane_part PR:000001444 ! cadherin-5
intersection_of: has_plasma_membrane_part PR:000002112 ! vascular endothelial growth factor receptor 2
intersection_of: has_plasma_membrane_part PR:000016043 ! T-cell acute lymphocytic leukemia protein 1
relationship: develops_from CL:0000134 ! mesenchymal stem cell
relationship: has_plasma_membrane_part PR:000001444 ! cadherin-5
relationship: has_plasma_membrane_part PR:000002112 ! vascular endothelial growth factor receptor 2
relationship: has_plasma_membrane_part PR:000016043 ! T-cell acute lymphocytic leukemia protein 1

[Term]
id: CL:0000569
name: cardiac mesenchymal cell
def: "A mesenchymal cell found in the developing heart and that develops into some part of the heart.  These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field." [PMID:18816864]
subset: cellxgene_subset
is_a: CL:0008019 ! mesenchymal cell
is_a: CL:2000073 ! migratory cardiac neural crest cell
intersection_of: CL:0008019 ! mesenchymal cell
intersection_of: develops_into CL:0002494 ! cardiocyte
relationship: develops_into CL:0002494 ! cardiocyte

[Term]
id: CL:0000573
name: retinal cone cell
def: "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." [MESH:D017949]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "cone" RELATED [doi:10.1038/s41598-020-66092-9]
xref: BTO:0001036
xref: CALOHA:TS-0866
xref: FMA:67748
is_a: CL:0010009 ! camera-type eye photoreceptor cell
relationship: develops_from CL:0002672 ! retinal progenitor cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000575
name: corneal epithelial cell
def: "An epithelial cell of the cornea." [GOC:tfm]
subset: cellxgene_subset
subset: eye_upper_slim
subset: human_reference_atlas
synonym: "epithelial cell of cornea" EXACT [FMA:70551]
xref: BTO:0004298
xref: CALOHA:TS-0173
xref: FMA:70551
is_a: CL:0000076 ! squamous epithelial cell
is_a: CL:0002159 ! general ecto-epithelial cell
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: CL:0000076 ! squamous epithelial cell
intersection_of: part_of UBERON:0001772 ! corneal epithelium
relationship: part_of UBERON:0001772 ! corneal epithelium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000586
name: germ cell
def: "The reproductive cell in multicellular organisms." [MESH:D005854]
subset: cellxgene_subset
xref: BTO:0000535
xref: NCIT:C12597
xref: VHOG:0001534
xref: WBbt:0006796
is_a: CL:0000039 {is_inferred="true"} ! germ line cell
relationship: capable_of_part_of GO:0009566 ! fertilization

[Term]
id: CL:0000593
name: androgen secreting cell
def: "A steroid hormone secreting cell that secretes androgen." [GOC:tfm]
is_a: CL:0000174 ! steroid hormone secreting cell
intersection_of: CL:0000151 ! secretory cell
intersection_of: capable_of GO:0035935 ! androgen secretion
relationship: capable_of GO:0035935 ! androgen secretion

[Term]
id: CL:0000595
name: enucleate erythrocyte
def: "An erythrocyte lacking a nucleus." [GOC:add, GOC:tfm]
subset: cellxgene_subset
synonym: "RBC" RELATED OMO:0003000 []
synonym: "red blood cell" BROAD []
is_a: CL:0000225 ! anucleate cell
is_a: CL:0000232 {is_inferred="true"} ! erythrocyte
intersection_of: CL:0000232 ! erythrocyte
intersection_of: has_characteristic PATO:0001405 ! anucleate
relationship: develops_from CL:0002422 ! enucleated reticulocyte

[Term]
id: CL:0000604
name: retinal rod cell
def: "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." [MESH:D017948]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "rod" RELATED [doi:10.1038/s41598-020-66092-9]
xref: BTO:0001024
xref: CALOHA:TS-0870
xref: FMA:67747
is_a: CL:0010009 ! camera-type eye photoreceptor cell
relationship: develops_from CL:0002672 ! retinal progenitor cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000622
name: acinar cell
def: "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus)." [GOC:tfm, http://www.copewithcytokines.de]
subset: cellxgene_subset
synonym: "acinic cell" EXACT []
synonym: "acinous cell" EXACT []
xref: FMA:83625
xref: MESH:D061354
is_a: CL:0000150 ! glandular epithelial cell
is_a: CL:0000154 ! protein secreting cell
relationship: part_of UBERON:0009842 ! glandular acinus

[Term]
id: CL:0000630
name: supporting cell
def: "A cell whose primary function is to support other cell types." [FB:ma, GOC:tfm]
subset: cellxgene_subset
synonym: "supportive cell" EXACT []
xref: BTO:0002315
is_a: CL:0000000 ! cell

[Term]
id: CL:0000656
name: primary spermatocyte
def: "A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes." [GOC:tfm, ISBN:0721662544]
xref: BTO:0001115
xref: CALOHA:TS-2194
xref: FMA:72292
is_a: CL:0000017 ! spermatocyte
intersection_of: CL:0000017 ! spermatocyte
intersection_of: capable_of GO:0007140 ! male meiotic nuclear division
intersection_of: has_characteristic PATO:0001394 ! diploid
relationship: capable_of GO:0007140 ! male meiotic nuclear division
relationship: has_characteristic PATO:0001394 ! diploid

[Term]
id: CL:0000657
name: secondary spermatocyte
def: "One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids." [GOC:tfm, ISBN:0721662544]
xref: BTO:0000709
xref: CALOHA:TS-2195
xref: FBbt:00004941
xref: FMA:72293
is_a: CL:0000017 ! spermatocyte
is_a: CL:0000413 ! haploid cell
intersection_of: CL:0000017 ! spermatocyte
intersection_of: capable_of GO:0007142 ! male meiosis II
intersection_of: has_characteristic PATO:0001375 ! haploid
relationship: capable_of GO:0007142 ! male meiosis II
relationship: develops_from CL:0000656 ! primary spermatocyte

[Term]
id: CL:0000667
name: collagen secreting cell
def: "An extracellular matrix secreting cell that secretes collagen." [GOC:tfm]
subset: cellxgene_subset
is_a: CL:0000327 ! extracellular matrix secreting cell

[Term]
id: CL:0000670
name: primordial germ cell
def: "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." [GOC:tfm, PMID:1381289]
subset: cellxgene_subset
synonym: "gonocyte" EXACT []
synonym: "primitive germ cell" EXACT []
xref: FMA:70567
is_a: CL:0000039 {is_inferred="true"} ! germ line cell
is_a: CL:0000219 {is_inferred="true"} ! motile cell
intersection_of: CL:0000039 ! germ line cell
intersection_of: capable_of GO:0048870 ! cell motility
intersection_of: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0000922 ! embryo

[Term]
id: CL:0000675
name: female gamete
def: "A mature sexual reproductive cell of the female germline." [GOC:tfm]
is_a: CL:0000021 {is_inferred="true"} ! female germ cell
is_a: CL:0000300 ! gamete

[Term]
id: CL:0000680
name: muscle precursor cell
def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add]
subset: cellxgene_subset
is_a: CL:0000055 ! non-terminally differentiated cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0011115 ! precursor cell
intersection_of: develops_into CL:0000187 ! muscle cell
relationship: develops_from CL:0000222 ! mesodermal cell
relationship: develops_into CL:0000187 ! muscle cell

[Term]
id: CL:0000696
name: PP cell
def: "A cell that stores and secretes pancreatic polypeptide hormone." [GOC:tfm, JB:jb, PMID:15153415]
subset: cellxgene_subset
synonym: "type F enteroendocrine cell" EXACT []
xref: FMA:62938
xref: FMA:83409
is_a: CL:0000164 ! enteroendocrine cell
is_a: CL:0000167 ! peptide hormone secreting cell

[Term]
id: CL:0000710
name: neurecto-epithelial cell
def: "Epithelial cells derived from neural plate and neural crest." [GOC:tfm]
comment: The term "neuroepithelial cell" is used to describe both this cell type and sensory epithelial cell (CL:0000098).
synonym: "neuroepithelial cell" BROAD []
xref: BTO:0004301
xref: FMA:70557
is_a: CL:0000075 ! columnar/cuboidal epithelial cell
is_a: CL:0002077 ! ecto-epithelial cell
intersection_of: CL:0002077 ! ecto-epithelial cell
intersection_of: develops_from CL:0000133 ! neurectodermal cell
relationship: develops_from CL:0000133 ! neurectodermal cell

[Term]
id: CL:0000723
name: somatic stem cell
def: "A stem cell that can give rise to cell types of the body other than those of the germ-line." [GO:0048103]
xref: CALOHA:TS-2086
xref: MESH:D053687
is_a: CL:0000034 ! stem cell
intersection_of: CL:0000034 ! stem cell
intersection_of: capable_of GO:0048103 ! somatic stem cell division
relationship: capable_of GO:0048103 ! somatic stem cell division

[Term]
id: CL:0000737
name: striated muscle cell
def: "Muscle cell which has as its direct parts myofilaments organized into sarcomeres." [GOC:tfm, ISBN:0721662544]
xref: BTO:0002916
xref: CALOHA:TS-2157
xref: FMA:86936
is_a: CL:0000187 ! muscle cell
intersection_of: CL:0000187 ! muscle cell
intersection_of: has_characteristic PATO:0001410 ! striated
intersection_of: has_part GO:0030017 ! sarcomere
disjoint_from: CL:0008000 ! non-striated muscle cell
relationship: has_characteristic PATO:0001410 ! striated
relationship: has_part GO:0030017 ! sarcomere

[Term]
id: CL:0000738
name: leukocyte
def: "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [GOC:add, GOC:tfm, ISBN:978-0-323-05290-0]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "immune cell" RELATED []
synonym: "leucocyte" EXACT []
synonym: "white blood cell" EXACT []
xref: BTO:0000751
xref: CALOHA:TS-0549
xref: FMA:62852
xref: MESH:D007962
xref: NCIT:C12529
is_a: CL:0000219 ! motile cell
is_a: CL:0000255 ! eukaryotic cell
is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell
is_a: CL:0002242 ! nucleate cell
intersection_of: CL:0000988 ! hematopoietic cell
intersection_of: capable_of GO:0001667 ! ameboidal-type cell migration
intersection_of: has_characteristic PATO:0002505 ! nucleated
relationship: capable_of GO:0001667 ! ameboidal-type cell migration
relationship: develops_from CL:0000037 ! hematopoietic stem cell
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0002405 ! immune system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000740
name: retinal ganglion cell
def: "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." [GOC:dph]
subset: cellxgene_subset
subset: eye_upper_slim
subset: human_reference_atlas
synonym: "gangliocyte" EXACT []
synonym: "ganglion cell of retina" EXACT []
synonym: "RGC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9]
synonym: "RGCs" RELATED OMO:0003004 [doi:10.1038/s41598-020-66092-9]
xref: BTO:0001800
xref: FMA:67765
xref: MESH:D012165
is_a: CL:0000117 ! CNS neuron (sensu Vertebrata)
relationship: has_soma_location UBERON:0000966 ! retina
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000746
name: cardiac muscle cell
alt_id: FMA:83808
def: "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei." [GOC:mtg_cardiacconduct_nov11, GOC:tfm, ISBN:0323052908, PMID:22426062, PMID:4711263]
comment: This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods.  The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein).  According to these refs, the cells participating in heart contraction in all cases are transversely striated.  Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction.
subset: cellxgene_subset
subset: general_cell_types_upper_slim
subset: human_reference_atlas
synonym: "cardiac muscle fiber" EXACT [GO:0048739]
synonym: "cardiac myocyte" EXACT []
synonym: "cardiocyte" BROAD []
synonym: "cardiomyocyte" EXACT []
synonym: "heart muscle cell" EXACT []
xref: BTO:0001539
xref: CALOHA:TS-0115
xref: FMA:14067
xref: MESH:D032383
is_a: CL:0000737 ! striated muscle cell
is_a: CL:0002494 ! cardiocyte
intersection_of: CL:0000187 ! muscle cell
intersection_of: has_characteristic PATO:0002478 ! transversely striated
intersection_of: has_part GO:0030017 ! sarcomere
intersection_of: part_of UBERON:0007100 ! primary circulatory organ
intersection_of: participates_in GO:0060047 ! heart contraction
relationship: develops_from CL:0000513 ! cardiac muscle myoblast
relationship: has_characteristic PATO:0002478 ! transversely striated
relationship: participates_in GO:0060047 ! heart contraction
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000763
name: myeloid cell
def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add]
subset: cellxgene_subset
xref: BTO:0001441
xref: CALOHA:TS-0647
xref: MESH:D022423
is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell
intersection_of: CL:0000988 ! hematopoietic cell
intersection_of: develops_from CL:0000049 ! common myeloid progenitor
relationship: develops_from CL:0000049 ! common myeloid progenitor

[Term]
id: CL:0000764
name: erythroid lineage cell
def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm]
comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes.
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "erythropoietic cell" EXACT []
xref: CALOHA:TS-0290
xref: FMA:62845
xref: FMA:83516
is_a: CL:0000763 ! myeloid cell
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000765
name: erythroblast
def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176]
subset: blood_and_immune_upper_slim
subset: cellxgene_subset
synonym: "normoblast" EXACT []
xref: BTO:0001571
xref: CALOHA:TS-0289
xref: FMA:83504
xref: MESH:D004900
is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell
is_a: CL:0011026 ! progenitor cell
intersection_of: CL:0000764 ! erythroid lineage cell
intersection_of: capable_of GO:0030218 ! erythrocyte differentiation
intersection_of: CL:4030045 GO:0005730 ! lacks_part nucleolus
intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
intersection_of: has_part GO:0005634 ! nucleus
relationship: capable_of GO:0030218 ! erythrocyte differentiation
relationship: CL:4030045 GO:0005730 ! lacks_part nucleolus
relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
relationship: develops_from CL:0000547 ! proerythroblast
relationship: has_part GO:0005634 ! nucleus

[Term]
id: CL:0000766
name: myeloid leukocyte
def: "A cell of the monocyte, granulocyte, or mast cell lineage." [GOC:add]
subset: cellxgene_subset
is_a: CL:0000738 {is_inferred="true"} ! leukocyte
is_a: CL:0000763 ! myeloid cell
intersection_of: CL:0000738 ! leukocyte
intersection_of: develops_from CL:0000049 ! common myeloid progenitor

[Term]
id: CL:0000783
name: multinucleated phagocyte
def: "A phagocyte formed by the fusion of mononuclear phagocytes." [GOC:add, GOC:tfm]
is_a: CL:0000228 ! multinucleate cell
is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata)
intersection_of: CL:0000518 ! phagocyte (sensu Vertebrata)
intersection_of: has_characteristic PATO:0001908 ! multinucleate

[Term]
id: CL:0000827
name: pro-T cell
def: "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." [GOC:add, ISBN:0781735149]
subset: cellxgene_subset
synonym: "DN1 cell" NARROW []
synonym: "DN1 thymocyte" NARROW []
synonym: "pro-T lymphocyte" EXACT []
synonym: "progenitor T cell" EXACT []
synonym: "TN1 cell" NARROW []
is_a: CL:0000838 {is_inferred="true"} ! lymphoid lineage restricted progenitor cell
intersection_of: CL:0000838 ! lymphoid lineage restricted progenitor cell
intersection_of: capable_of GO:0030217 ! T cell differentiation
relationship: capable_of GO:0030217 ! T cell differentiation
relationship: develops_from CL:0000051 ! common lymphoid progenitor

[Term]
id: CL:0000837
name: hematopoietic multipotent progenitor cell
def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770]
comment: Markers differ between mouse and human.
subset: blood_and_immune_upper_slim
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "hemopoietic progenitor cell" EXACT []
synonym: "MPP" EXACT []
xref: BTO:0000725
xref: CALOHA:TS-0448
is_a: CL:0008001 ! hematopoietic precursor cell
is_a: PR:000050567 ! protein-containing material entity
intersection_of: CL:0000988 ! hematopoietic cell
intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha
intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse)
intersection_of: has_characteristic PATO:0001402 ! multipotent
intersection_of: has_plasma_membrane_part PR:000001003 ! CD34 molecule
disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell
relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha
relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse)
relationship: develops_from CL:0000037 ! hematopoietic stem cell
relationship: has_characteristic PATO:0001402 ! multipotent
relationship: has_plasma_membrane_part PR:000001003 ! CD34 molecule
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000838
name: lymphoid lineage restricted progenitor cell
def: "A progenitor cell restricted to the lymphoid lineage." [GOC:add, GOC:tfm]
comment: Note that this is a class of cell types, not an identified single cell type.
subset: cellxgene_subset
synonym: "lymphoid progenitor cell" BROAD []
xref: BTO:0004731
xref: CALOHA:TS-2025
xref: FMA:70338
is_a: CL:0002031 {is_inferred="true"} ! hematopoietic lineage restricted progenitor cell
is_a: CL:0011026 ! progenitor cell
intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell
intersection_of: capable_of GO:0030098 ! lymphocyte differentiation
disjoint_from: CL:0000839 ! myeloid lineage restricted progenitor cell
relationship: capable_of GO:0030098 ! lymphocyte differentiation

[Term]
id: CL:0000839
name: myeloid lineage restricted progenitor cell
def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770]
comment: Note that this is a class of cell types, not an identified single cell type.
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "myeloid progenitor cell" BROAD []
xref: BTO:0004730
xref: CALOHA:TS-2099
xref: FMA:70339
is_a: CL:0002031 {is_inferred="true"} ! hematopoietic lineage restricted progenitor cell
is_a: CL:0011026 ! progenitor cell
intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell
intersection_of: capable_of GO:0030099 ! myeloid cell differentiation
relationship: capable_of GO:0030099 ! myeloid cell differentiation
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0000842
name: mononuclear cell
def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add]
subset: blood_and_immune_upper_slim
subset: cellxgene_subset
synonym: "mononuclear leukocyte" EXACT []
synonym: "peripheral blood mononuclear cell" NARROW []
xref: BTO:0000878
xref: CALOHA:TS-0768
xref: FMA:86713
is_a: CL:0000226 ! single nucleate cell
is_a: CL:0000738 {is_inferred="true"} ! leukocyte
intersection_of: CL:0000738 ! leukocyte
intersection_of: has_characteristic PATO:0001407 ! mononucleate

[Term]
id: CL:0000850
name: serotonergic neuron
def: "A neuron that releases serotonin as a neurotransmitter." [SANBI:mhl]
synonym: "5-HT neuron" EXACT []
synonym: "5-hydroxytryptamine neuron" EXACT []
synonym: "serotinergic neuron" RELATED []
xref: FBbt:00005133
xref: MESH:D059326
xref: WBbt:0006837
is_a: CL:0000458 ! serotonin secreting cell
is_a: CL:0000540 ! neuron
intersection_of: CL:0000540 ! neuron
intersection_of: capable_of GO:0060096 ! serotonin secretion, neurotransmission
relationship: capable_of GO:0060096 ! serotonin secretion, neurotransmission

[Term]
id: CL:0000988
name: hematopoietic cell
def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add]
subset: cellxgene_subset
synonym: "haematopoietic cell" EXACT []
synonym: "haemopoietic cell" EXACT []
synonym: "hemopoietic cell" EXACT []
xref: BTO:0000574
xref: CALOHA:TS-2017
xref: FMA:70366
xref: FMA:83598
is_a: CL:0000000 ! cell

[Term]
id: CL:0001035
name: bone cell
def: "A connective tissue cell found in bone." [GO_REF:0000034, GOC:add]
subset: general_cell_types_upper_slim
subset: human_reference_atlas
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0001474 ! bone element
relationship: part_of UBERON:0001474 ! bone element
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-9990-8331
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2011-11-16T04:28:16Z

[Term]
id: CL:0001060
name: hematopoietic oligopotent progenitor cell, lineage-negative
def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers." [GOC:tfm, PMID:19022770]
is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell
intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell
intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse)
intersection_of: has_characteristic PATO:0001401 ! oligopotent
relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse)
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-01-06T03:43:27Z

[Term]
id: CL:0001066
name: erythroid progenitor cell, mammalian
def: "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative)." [GOC:add, ISBN:0721601464]
subset: cellxgene_subset
synonym: "BFU-E" RELATED OMO:0003000 []
synonym: "blast forming unit erythroid" RELATED []
synonym: "burst forming unit erythroid" RELATED []
synonym: "CFU-E" RELATED OMO:0003000 []
synonym: "colony forming unit erythroid" RELATED []
synonym: "erythroid stem cell" RELATED []
xref: BTO:0004911
is_a: CL:0000038 ! erythroid progenitor cell
is_a: PR:000050567 ! protein-containing material entity
intersection_of: CL:0000038 ! erythroid progenitor cell
intersection_of: capable_of GO:0030218 ! erythrocyte differentiation
intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1
relationship: capable_of GO:0030218 ! erythrocyte differentiation
relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule
relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule
relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M
relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon
relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1
relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule
relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain
relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1
relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5
relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule
relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G
relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1

[Term]
id: CL:0002031
name: hematopoietic lineage restricted progenitor cell
def: "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells." [GOC:tfm, PMID:19022770]
subset: blood_and_immune_upper_slim
is_a: CL:0008001 ! hematopoietic precursor cell
intersection_of: CL:0000988 ! hematopoietic cell
intersection_of: has_characteristic PATO:0001400 ! unipotent
disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell
relationship: develops_from CL:0002032 ! hematopoietic oligopotent progenitor cell
relationship: has_characteristic PATO:0001400 ! unipotent
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-01-06T03:43:20Z

[Term]
id: CL:0002032
name: hematopoietic oligopotent progenitor cell
def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities." [GOC:tfm, https://orcid.org/0000-0001-5208-3432, PMID:19022770]
comment: This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell.  For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060).
subset: blood_and_immune_upper_slim
is_a: CL:0008001 ! hematopoietic precursor cell
intersection_of: CL:0000988 ! hematopoietic cell
intersection_of: has_characteristic PATO:0001401 ! oligopotent
relationship: develops_from CL:0000837 ! hematopoietic multipotent progenitor cell
relationship: has_characteristic PATO:0001401 ! oligopotent
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-01-06T03:43:27Z

[Term]
id: CL:0002064
name: pancreatic acinar cell
def: "A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules." [GOC:tfm, http://www.copewithcytokines.de/cope.cgi?key=pancreatic%20acinar%20cells, ISBN:0517223651, PMID:20395539]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "acinar cell of pancreas" EXACT []
xref: BTO:0000028
xref: CALOHA:TS-0737
xref: FMA:63032
is_a: CL:0000622 {is_inferred="true"} ! acinar cell
is_a: CL:1001599 ! pancreas exocrine glandular cell
intersection_of: CL:0000622 ! acinar cell
intersection_of: part_of UBERON:0001263 ! pancreatic acinus
relationship: has_part GO:0042589 ! zymogen granule membrane
relationship: part_of UBERON:0001263 ! pancreatic acinus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-06-24T03:16:29Z

[Term]
id: CL:0002067
name: type A enteroendocrine cell
def: "An enteroendocrine cell that produces glucagon." [GOC:tfm, ISBN:0412046911]
xref: FMA:62939
is_a: CL:0000164 ! enteroendocrine cell
is_a: CL:0000170 ! glucagon secreting cell
intersection_of: CL:0000164 ! enteroendocrine cell
intersection_of: capable_of GO:0070091 ! glucagon secretion
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-10T10:48:54Z

[Term]
id: CL:0002068
name: Purkinje myocyte
def: "Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter." [FMA:0412046911, GOC:tfm, PMID:19939742]
subset: human_reference_atlas
synonym: "myocytus conducens cardiacus" EXACT []
synonym: "Purkinje cell fiber" EXACT []
synonym: "Purkinje muscle cell" EXACT []
xref: BTO:0001032
xref: FMA:14146
is_a: CL:0002086 ! specialized cardiac myocyte
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-06-28T08:36:15Z

[Term]
id: CL:0002072
name: nodal myocyte
def: "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery." [FMA:67101, GOC:tfm]
synonym: "cardiac pacemaker cell" EXACT [GOC:pr]
synonym: "myocytus nodalis" EXACT []
synonym: "P cell" EXACT []
synonym: "pacemaker cell" BROAD []
xref: BTO:0004190
xref: FMA:67101
is_a: CL:0002086 ! specialized cardiac myocyte
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-06-29T11:41:37Z

[Term]
id: CL:0002073
name: transitional myocyte
def: "Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes." [FMA:67142, GOC:tfm]
xref: FMA:67142
is_a: CL:0002086 ! specialized cardiac myocyte
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-06-29T02:39:32Z

[Term]
id: CL:0002074
name: myocardial endocrine cell
def: "The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides)." [FMA:67111, GOC:tfm]
xref: FMA:67111
is_a: CL:0000163 ! endocrine cell
is_a: CL:0002086 ! specialized cardiac myocyte
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-06-29T11:50:47Z

[Term]
id: CL:0002076
name: endo-epithelial cell
def: "An epithelial cell derived from endoderm." [FMA:69075, GOC:tfm]
xref: FMA:69075
is_a: CL:0000066 ! epithelial cell
is_a: UBERON:0004119 ! endoderm-derived structure
relationship: develops_from CL:0000223 ! endodermal cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-06-29T03:38:14Z

[Term]
id: CL:0002077
name: ecto-epithelial cell
def: "An epithelial cell derived from ectoderm." [FMA:69074, GOC:tfm]
xref: FMA:69074
is_a: CL:0000066 ! epithelial cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: develops_from CL:0000221 ! ectodermal cell
relationship: develops_from CL:0000221 ! ectodermal cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-06-29T03:38:22Z

[Term]
id: CL:0002078
name: meso-epithelial cell
def: "Epithelial cell derived from mesoderm or mesenchyme." [FMA:69076, GOC:tfm]
synonym: "epithelial mesenchymal cell" EXACT []
xref: FMA:69076
is_a: CL:0000066 ! epithelial cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: develops_from CL:0000222 ! mesodermal cell
relationship: develops_from CL:0000222 ! mesodermal cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-06-29T03:49:14Z

[Term]
id: CL:0002079
name: pancreatic ductal cell
def: "Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH." [FMA:63099, GOC:tfm, PMID:14740223]
subset: cellxgene_subset
subset: human_reference_atlas
xref: FMA:63099
is_a: CL:0000069 ! branched duct epithelial cell
is_a: CL:1001433 ! epithelial cell of exocrine pancreas
intersection_of: CL:0000083 ! epithelial cell of pancreas
intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity
intersection_of: part_of UBERON:0001064 ! ventral pancreatic duct
relationship: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity
relationship: part_of UBERON:0001064 ! ventral pancreatic duct
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-06-30T08:49:43Z

[Term]
id: CL:0002080
name: pancreatic centro-acinar cell
def: "A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types." [GOC:tfm, PMID:12142741, PMID:20018761, PMID:8185160]
subset: human_reference_atlas
synonym: "centroacinar cell of Langerhans" EXACT []
synonym: "pancreatic centroacinar cell" EXACT []
xref: FMA:62455
is_a: CL:1001433 ! epithelial cell of exocrine pancreas
intersection_of: CL:0000083 ! epithelial cell of pancreas
intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity
intersection_of: part_of UBERON:0001263 ! pancreatic acinus
relationship: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity
relationship: part_of UBERON:0001263 ! pancreatic acinus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-06-30T08:49:52Z

[Term]
id: CL:0002086
name: specialized cardiac myocyte
def: "A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart." [FMA:67968, GOC:tfm]
xref: FMA:67968
is_a: CL:0000746 ! cardiac muscle cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-07-21T01:33:38Z

[Term]
id: CL:0002087
name: nongranular leukocyte
def: "A leukocyte that lacks granules." [GOC:tfm]
subset: blood_and_immune_upper_slim
synonym: "agranular leukocyte" EXACT []
xref: FMA:62855
is_a: CL:0000738 {is_inferred="true"} ! leukocyte
intersection_of: CL:0000738 ! leukocyte
intersection_of: CL:4030045 GO:0030141 ! lacks_part secretory granule
relationship: CL:4030045 GO:0030141 ! lacks_part secretory granule
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-07-22T11:30:33Z

[Term]
id: CL:0002088
name: interstitial cell of Cajal
def: "This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise." [GOC:tfm, PMID:16460275, PMID:19520112]
comment: Some argue this cell type is of mesenchymal origin.
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "ICC" EXACT []
synonym: "intestinal pacemaker cell" EXACT [GOC:pr]
xref: BTO:0003914
xref: FMA:86573
is_a: CL:0000710 {is_inferred="true"} ! neurecto-epithelial cell
intersection_of: CL:0000710 ! neurecto-epithelial cell
intersection_of: capable_of GO:0043134 ! regulation of hindgut contraction
relationship: capable_of GO:0043134 ! regulation of hindgut contraction
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-07-22T03:26:00Z

[Term]
id: CL:0002092
name: bone marrow cell
def: "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." [GOC:tfm, ISBN:0618947256]
comment: MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense.
subset: cellxgene_subset
xref: BTO:0004850
xref: FMA:83621
xref: MESH:D001854
is_a: CL:0001035 {is_inferred="true"} ! bone cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0001035 ! bone cell
intersection_of: part_of UBERON:0002371 ! bone marrow
relationship: part_of UBERON:0002371 ! bone marrow
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-07-22T04:48:15Z

[Term]
id: CL:0002095
name: hilus cell of ovary
def: "A cell in the hilum of the ovary that produces androgens." [GOC:tfm, ISBN:068340007X]
subset: human_reference_atlas
synonym: "hilar cell of ovary" EXACT []
xref: FMA:18710
is_a: CL:0000593 ! androgen secreting cell
is_a: CL:0002132 ! stromal cell of ovary
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-08-23T11:18:18Z

[Term]
id: CL:0002132
name: stromal cell of ovary
def: "A stomal cell of the ovary" [GOC:tfm]
subset: cellxgene_subset
synonym: "ovarian stromal cell" EXACT [GOC:cjm]
xref: FMA:72299
is_a: CL:0000499 ! stromal cell
intersection_of: CL:0000499 ! stromal cell
intersection_of: part_of UBERON:0000992 ! ovary
relationship: part_of UBERON:0000992 ! ovary
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-08-23T12:10:31Z

[Term]
id: CL:0002139
name: endothelial cell of vascular tree
def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659]
comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive.
subset: cellxgene_subset
synonym: "cubodial endothelial cell of vascular tree" NARROW []
synonym: "vascular endothelial cell" EXACT []
xref: BTO:0001854
xref: CALOHA:TS-1106
xref: FMA:67755
is_a: CL:0000115 ! endothelial cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-08-24T02:06:40Z

[Term]
id: CL:0002144
name: capillary endothelial cell
def: "An endothelial cell found in capillaries." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
xref: BTO:0004956
xref: CALOHA:TS-0112
xref: FMA:67756
is_a: CL:2000008 ! microvascular endothelial cell
intersection_of: CL:0000071 ! blood vessel endothelial cell
intersection_of: part_of UBERON:0001915 ! endothelium of capillary
relationship: part_of UBERON:0001915 ! endothelium of capillary
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-08-24T10:15:00Z

[Term]
id: CL:0002149
name: epithelial cell of uterus
def: "An epithelial cell of the uterus." [GOC:tfm]
subset: cellxgene_subset
xref: FMA:256161
is_a: CL:0002076 {is_inferred="true"} ! endo-epithelial cell
intersection_of: CL:0002076 ! endo-epithelial cell
intersection_of: part_of UBERON:0000995 ! uterus
relationship: part_of UBERON:0000995 ! uterus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-08-24T10:45:54Z

[Term]
id: CL:0002159
name: general ecto-epithelial cell
def: "Epithelial cells derived from general body ectoderm and ectoderm placodes." [GOC:tfm]
xref: FMA:70556
is_a: CL:0002077 ! ecto-epithelial cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-08-26T08:31:08Z

[Term]
id: CL:0002178
name: epithelial cell of stomach
def: "An epithelial cell found in the lining of the stomach." [GOC:tfm]
xref: FMA:62948
is_a: CL:0002251 {is_inferred="true"} ! epithelial cell of alimentary canal
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0000945 ! stomach
relationship: part_of UBERON:0000945 ! stomach
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-08-25T03:22:08Z

[Term]
id: CL:0002180
name: mucous cell of stomach
def: "A mucous cell in the epithelium of the stomach." [GOC:tfm]
xref: FMA:63464
is_a: CL:0002659 ! glandular cell of stomach
intersection_of: CL:0002178 ! epithelial cell of stomach
intersection_of: part_of UBERON:0001199 ! mucosa of stomach
relationship: part_of UBERON:0001199 ! mucosa of stomach
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-08-25T03:38:51Z

[Term]
id: CL:0002183
name: stem cell of gastric gland
def: "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit." [GOC:tfm, ISBN:0517223651]
xref: FMA:62953
is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell
is_a: CL:0000152 ! exocrine cell
is_a: CL:0002180 ! mucous cell of stomach
intersection_of: CL:0000048 ! multi fate stem cell
intersection_of: part_of UBERON:0000325 ! gastric gland
relationship: part_of UBERON:0000325 ! gastric gland
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-08-25T03:57:08Z

[Term]
id: CL:0002195
name: hepatic stem cell
def: "A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes)." [GOC:tfm, PMID:26798363]
synonym: "HpSC" RELATED OMO:0003000 [PMID:18442648]
xref: FMA:86577
is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000048 ! multi fate stem cell
intersection_of: part_of UBERON:0002107 ! liver
relationship: part_of UBERON:0002107 ! liver
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" xsd:string
creation_date: 2010-08-30T02:00:42Z

[Term]
id: CL:0002222
name: vertebrate lens cell
def: "A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye." [GOC:tfm, ISBN:0721662544]
subset: eye_upper_slim
xref: FMA:70950
is_a: CL:0000066 ! epithelial cell
is_a: CL:0000306 ! crystallin accumulating cell
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: part_of UBERON:0000965 ! lens of camera-type eye
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-07T10:38:03Z

[Term]
id: CL:0002224
name: lens epithelial cell
def: "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth." [GOC:tfm, http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium, ISBN:0721662544]
subset: cellxgene_subset
subset: human_reference_atlas
xref: FMA:67559
is_a: CL:0000075 {is_inferred="true"} ! columnar/cuboidal epithelial cell
is_a: CL:0002222 ! vertebrate lens cell
intersection_of: CL:0000075 ! columnar/cuboidal epithelial cell
intersection_of: part_of UBERON:0001803 ! epithelium of lens
relationship: part_of UBERON:0001803 ! epithelium of lens
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-09-07T10:45:47Z

[Term]
id: CL:0002240
name: marrow fibroblast
def: "A fibroblast in the bone marrow." [GOC:tfm]
xref: FMA:84377
is_a: CL:0000057 ! fibroblast
is_a: CL:0002092 ! bone marrow cell
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0002371 ! bone marrow
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-07T02:25:18Z

[Term]
id: CL:0002241
name: pulmonary interstitial fibroblast
def: "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis." [GOC:tfm]
subset: cellxgene_subset
synonym: "pulmonary myofibroblast" EXACT []
synonym: "pulmonary septal cell" EXACT []
xref: FMA:84467
is_a: CL:0000057 {is_inferred="true"} ! fibroblast
is_a: CL:4030031 ! interstitial cell
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0001004 ! respiratory system
intersection_of: part_of UBERON:0005169 ! interstitial tissue
relationship: part_of UBERON:0001004 ! respiratory system
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-07T02:29:38Z

[Term]
id: CL:0002242
name: nucleate cell
def: "A cell containing at least one nucleus." [GOC:tfm]
xref: FMA:67513
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: has_characteristic PATO:0002505 ! nucleated
relationship: has_characteristic PATO:0002505 ! nucleated
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-07T03:32:33Z

[Term]
id: CL:0002243
name: smooth muscle cell of sphincter of pupil
def: "A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells." [GOC:tfm, ISBN:0721662544, ISBN:0721694128]
subset: cellxgene_subset
synonym: "smooth muscle fiber of sphincter of pupil" EXACT []
synonym: "smooth muscle fibre of sphincter of pupil" RELATED []
xref: FMA:70611
is_a: CL:0000358 {is_inferred="true"} ! sphincter associated smooth muscle cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0001607 ! sphincter pupillae
relationship: develops_from CL:0000133 ! neurectodermal cell
relationship: part_of UBERON:0001607 ! sphincter pupillae
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-08T08:53:42Z

[Term]
id: CL:0002246
name: peripheral blood stem cell
def: "A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells)." [GOC:tfm]
synonym: "PBSC" EXACT []
xref: BTO:0002669
xref: FMA:86711
xref: MESH:D000072916
is_a: CL:0000037 {is_inferred="true"} ! hematopoietic stem cell
is_a: CL:0000080 ! circulating cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000037 ! hematopoietic stem cell
intersection_of: part_of UBERON:0000178 ! blood
relationship: part_of UBERON:0000178 ! blood
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-07T03:57:09Z

[Term]
id: CL:0002251
name: epithelial cell of alimentary canal
def: "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus." [GOC:tfm, ISBN:0721662544]
is_a: CL:0002076 ! endo-epithelial cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0001555 ! digestive tract
relationship: part_of UBERON:0001555 ! digestive tract
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-08T09:26:53Z

[Term]
id: CL:0002252
name: epithelial cell of esophagus
def: "An epithelial cell of the esophagus." [GOC:tfm]
subset: cellxgene_subset
xref: FMA:63071
is_a: CL:0002251 {is_inferred="true"} ! epithelial cell of alimentary canal
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001043 ! esophagus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-08T09:28:20Z

[Term]
id: CL:0002253
name: epithelial cell of large intestine
def: "An epithelial cell of the large intestine." [GOC:tfm]
subset: cellxgene_subset
synonym: "epithelial cell of colon" RELATED []
xref: BTO:0004297
xref: FMA:256157
is_a: CL:0002563 {is_inferred="true"} ! intestinal epithelial cell
intersection_of: CL:0002563 ! intestinal epithelial cell
intersection_of: part_of UBERON:0000059 ! large intestine
relationship: part_of UBERON:0000059 ! large intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-08T09:28:22Z

[Term]
id: CL:0002254
name: epithelial cell of small intestine
def: "An epithelial cell of the small intestine." [GOC:tfm]
subset: cellxgene_subset
xref: FMA:256159
is_a: CL:0002563 {is_inferred="true"} ! intestinal epithelial cell
intersection_of: CL:0002563 ! intestinal epithelial cell
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0002108 ! small intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-08T09:41:46Z

[Term]
id: CL:0002255
name: stromal cell of endometrium
def: "A stromal cell of the endometrium that is fibroblastic in appearance. During decidualization this cell may differentiate into a decidual stromal cell." [https://doi.org/10.1038/s41591-020-1040-z, PMID:11331626, PMID:30013421, PMID:30309298, Wiki:Decidualization&oldid=908981933#Endometrial_stromal_cells_(ESCs)]
subset: human_reference_atlas
synonym: "endometrial stromal cell" EXACT []
synonym: "endometrial stromal fibroblast" EXACT [PMID:30309298]
xref: CALOHA:TS-1266
xref: FMA:86490
is_a: CL:0000499 {is_inferred="true"} ! stromal cell
intersection_of: CL:0000499 ! stromal cell
intersection_of: part_of UBERON:0001295 ! endometrium
relationship: has_potential_to_directly_develop_into CL:2000002 ! decidual cell
relationship: part_of UBERON:0002337 ! endometrial stroma
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-09-08T09:50:04Z

[Term]
id: CL:0002262
name: endothelial cell of sinusoid
def: "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver." [GOC:tfm, ISBN:0618947256]
subset: cellxgene_subset
subset: human_reference_atlas
xref: FMA:63134
is_a: CL:0000115 ! endothelial cell
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0003909 ! sinusoid
relationship: part_of UBERON:0003909 ! sinusoid
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-09-14T10:57:26Z

[Term]
id: CL:0002264
name: type A cell of stomach
def: "A type of enteroendocrine cell found in the stomach that secretes glucagon." [GOC:tfm]
xref: FMA:83411
is_a: CL:0002067 ! type A enteroendocrine cell
is_a: CL:0002659 ! glandular cell of stomach
intersection_of: CL:0002067 ! type A enteroendocrine cell
intersection_of: part_of UBERON:0000945 ! stomach
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-10T10:54:42Z

[Term]
id: CL:0002265
name: type D cell of colon
def: "A D cell located in the colon." [GOC:tfm]
synonym: "colon D-cell" EXACT []
synonym: "colonic delta cell" EXACT []
synonym: "delta cell of colon" EXACT []
xref: FMA:268744
is_a: CL:0000502 ! type D enteroendocrine cell
is_a: CL:0009042 ! enteroendocrine cell of colon
intersection_of: CL:0000502 ! type D enteroendocrine cell
intersection_of: part_of UBERON:0001155 ! colon
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-10T11:37:35Z

[Term]
id: CL:0002266
name: type D cell of small intestine
def: "A type D cell of the small intestine." [GOC:tfm]
synonym: "delta cell of small intestine" EXACT []
synonym: "small intestine D-cell" EXACT []
synonym: "small intestine delta cell" EXACT []
xref: FMA:268736
is_a: CL:0000502 ! type D enteroendocrine cell
is_a: CL:0009006 ! enteroendocrine cell of small intestine
intersection_of: CL:0000502 ! type D enteroendocrine cell
intersection_of: part_of UBERON:0002108 ! small intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-10T01:34:22Z

[Term]
id: CL:0002267
name: type D cell of stomach
def: "A type D cell found in the stomach." [GOC:tfm]
synonym: "delta cell of stomach" EXACT []
synonym: "stomach D-cell" EXACT []
synonym: "stomach delta cell" EXACT []
xref: FMA:83410
is_a: CL:0000502 ! type D enteroendocrine cell
is_a: CL:0002659 ! glandular cell of stomach
intersection_of: CL:0000502 ! type D enteroendocrine cell
intersection_of: part_of UBERON:0000945 ! stomach
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-10T01:36:03Z

[Term]
id: CL:0002275
name: pancreatic PP cell
def: "A PP cell located in the islets of the pancreas." [GOC:tfm]
comment: The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell.
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "pancreatic polypeptide-secreting cell" EXACT []
synonym: "PP cell of pancreatic islet" EXACT []
synonym: "PP-cell of pancreatic islet" EXACT []
xref: BTO:0000805
xref: FMA:70588
xref: MESH:D050418
is_a: CL:0000696 ! PP cell
is_a: CL:0008024 ! pancreatic endocrine cell
intersection_of: CL:0000696 ! PP cell
intersection_of: part_of UBERON:0000006 ! islet of Langerhans
intersection_of: part_of UBERON:0001264 ! pancreas
relationship: part_of UBERON:0000006 ! islet of Langerhans
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-09-10T03:30:31Z

[Term]
id: CL:0002308
name: epithelial cell of skin gland
def: "An epithelial cell of a skin gland." [GOC:tfm]
synonym: "epithelial cell of gland of skin" EXACT []
xref: FMA:70657
is_a: CL:0002159 ! general ecto-epithelial cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0002419 ! skin gland
relationship: part_of UBERON:0002419 ! skin gland
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-14T12:00:07Z

[Term]
id: CL:0002319
name: neural cell
def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256]
subset: cellxgene_subset
xref: CALOHA:TS-2040
xref: FMA:70333
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0001016 ! nervous system
relationship: part_of UBERON:0001016 ! nervous system
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-15T01:34:57Z

[Term]
id: CL:0002320
name: connective tissue cell
def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256]
subset: cellxgene_subset
xref: CALOHA:TS-2096
xref: FMA:63875
xref: MESH:D003239
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0002384 ! connective tissue
relationship: part_of UBERON:0002384 ! connective tissue
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-15T03:01:54Z

[Term]
id: CL:0002321
name: embryonic cell (metazoa)
def: "A cell of the embryo." [FMA:0618947256]
xref: CALOHA:TS-0263
xref: FMA:82840
xref: WBbt:0007028
is_a: CL:0000000 ! cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-15T03:39:21Z

[Term]
id: CL:0002333
name: neural crest derived adipocyte
def: "An adipocyte derived from a neural crest cell." [GOC:tfm, PMID:17507398]
is_a: CL:0000136 ! adipocyte
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: CL:0000136 ! adipocyte
intersection_of: develops_from CL:0000333 ! migratory neural crest cell
relationship: develops_from CL:0000005 ! fibroblast neural crest derived
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-20T02:25:25Z

[Term]
id: CL:0002350
name: endocardial cell
def: "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin." [GOC:tfm, ISSN:0452-3458]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "endocardial endothelial cell" EXACT []
synonym: "endothelial cell of endocardium" EXACT [FMA:75621]
xref: FMA:75621
is_a: CL:0010008 ! cardiac endothelial cell
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0002165 ! endocardium
relationship: part_of UBERON:0002165 ! endocardium
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-09-21T04:33:05Z

[Term]
id: CL:0002351
name: progenitor cell of endocrine pancreas
def: "A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1." [GOC:tfm, PMID:20025937, PMID:20217494, PMID:22728667]
subset: cellxgene_subset
synonym: "pancreatic endocrine progenitor" EXACT []
synonym: "pancreatic islet progenitor cell" EXACT []
is_a: CL:0011026 ! progenitor cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-21T04:41:06Z

[Term]
id: CL:0002352
name: gestational hematopoietic stem cell
def: "A hematopoietic stem cell that exists during embryogenesis." [GOC:tfm, ISBN:978-60327-246-6]
is_a: CL:0000037 ! hematopoietic stem cell
intersection_of: CL:0000037 ! hematopoietic stem cell
intersection_of: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0000922 ! embryo
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-22T09:05:13Z

[Term]
id: CL:0002359
name: placental hematopoietic stem cell
def: "A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells." [GOC:tfm, ISBN:978-1-60327-346-6]
is_a: CL:0002352 ! gestational hematopoietic stem cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000037 ! hematopoietic stem cell
intersection_of: part_of UBERON:0001987 ! placenta
relationship: part_of UBERON:0001987 ! placenta
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-22T10:30:02Z

[Term]
id: CL:0002363
name: keratocyte
def: "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate." [GOC:tfm, ISBN:9780702029585]
subset: cellxgene_subset
subset: eye_upper_slim
subset: human_reference_atlas
synonym: "corneal fibroblast" EXACT []
synonym: "corneal keratocyte" EXACT []
is_a: CL:0000005 ! fibroblast neural crest derived
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0001777 ! substantia propria of cornea
relationship: part_of UBERON:0001777 ! substantia propria of cornea
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2010-09-22T01:57:40Z

[Term]
id: CL:0002368
name: respiratory epithelial cell
def: "An endo-epithelial cell of the respiratory tract." [GOC:tfm]
subset: cellxgene_subset
synonym: "airway epithelial cell" EXACT []
xref: BTO:0004533
is_a: CL:0002076 {is_inferred="true"} ! endo-epithelial cell
intersection_of: CL:0002076 ! endo-epithelial cell
intersection_of: part_of UBERON:0000065 ! respiratory tract
relationship: part_of UBERON:0000065 ! respiratory tract
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-23T04:38:49Z

[Term]
id: CL:0002372
name: myotube
def: "A transversely striated, synctial muscle cell, formed by the fusion of myoblasts." [GOC:dos, GOC:tfm, ISBN:0323052908, PMID:22274696]
synonym: "myotubule" EXACT []
synonym: "single cell sarcomere" EXACT []
xref: FBbt:00005812
is_a: CL:0000228 ! multinucleate cell
is_a: CL:0000737 ! striated muscle cell
intersection_of: CL:0000187 ! muscle cell
intersection_of: has_characteristic PATO:0001908 ! multinucleate
intersection_of: has_characteristic PATO:0002478 ! transversely striated
intersection_of: has_part GO:0030017 ! sarcomere
relationship: has_characteristic PATO:0002478 ! transversely striated
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-09-24T01:13:01Z

[Term]
id: CL:0002421
name: nucleated reticulocyte
def: "A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles." [GOC:tfm, PMID:18182572, PMID:9011180, PMID:9046052]
is_a: CL:0000558 {is_inferred="true"} ! reticulocyte
is_a: CL:0002242 ! nucleate cell
intersection_of: CL:0000558 ! reticulocyte
intersection_of: has_characteristic PATO:0002505 ! nucleated
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-10-15T09:24:05Z

[Term]
id: CL:0002422
name: enucleated reticulocyte
def: "A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes." [GOC:tfm, ISBN:0-12203-052-4, ISBN:0721601464]
subset: cellxgene_subset
xref: CALOHA:TS-0864
xref: FMA:66785
is_a: CL:0000225 ! anucleate cell
is_a: CL:0000558 {is_inferred="true"} ! reticulocyte
intersection_of: CL:0000558 ! reticulocyte
intersection_of: has_characteristic PATO:0001405 ! anucleate
intersection_of: has_part GO:0005840 ! ribosome
relationship: has_part GO:0005840 ! ribosome
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-10-15T09:24:08Z

[Term]
id: CL:0002494
name: cardiocyte
def: "A cell located in the heart, including both muscle and non muscle cells." [GOC:tfm]
comment: From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart.
synonym: "heart cell" EXACT []
xref: BTO:0001539
xref: CALOHA:TS-0115
xref: FMA:83808
xref: FMA:84791
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0007100 ! primary circulatory organ
relationship: part_of UBERON:0007100 ! primary circulatory organ
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-12-07T09:37:22Z

[Term]
id: CL:0002503
name: adventitial cell
def: "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc" [GOC:tfm]
subset: cellxgene_subset
xref: BTO:0002441
xref: FMA:84639
is_a: CL:0000630 ! supporting cell
is_a: CL:0002320 ! connective tissue cell
intersection_of: CL:0002320 ! connective tissue cell
intersection_of: part_of UBERON:0005742 ! adventitia
relationship: part_of UBERON:0005742 ! adventitia
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-12-07T04:03:56Z

[Term]
id: CL:0002504
name: enteric smooth muscle cell
def: "A smooth muscle cell of the intestine." [GOC:tfm]
subset: cellxgene_subset
synonym: "intestinal smooth muscle cell" EXACT []
is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0000160 ! intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-01-17T03:39:38Z

[Term]
id: CL:0002518
name: kidney epithelial cell
def: "An epithelial cell of the kidney." [GOC:tfm, KUPO:SJ]
subset: cellxgene_subset
xref: KUPO:0001019
is_a: CL:0000066 ! epithelial cell
is_a: CL:1000497 {is_inferred="true"} ! kidney cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0002113 ! kidney
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-02-08T10:46:34Z

[Term]
id: CL:0002521
name: subcutaneous adipocyte
def: "An adipocyte that is part of subcutaneous adipose tissue." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "subcutaneous fat cell" EXACT []
is_a: CL:0000136 {is_inferred="true"} ! adipocyte
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000136 ! adipocyte
intersection_of: part_of UBERON:0002190 ! subcutaneous adipose tissue
relationship: part_of UBERON:0002190 ! subcutaneous adipose tissue
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2011-02-21T02:51:22Z

[Term]
id: CL:0002538
name: intrahepatic cholangiocyte
def: "An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes." [GOC:tfm, PMID:23720296]
subset: cellxgene_subset
synonym: "small bile duct cholangiocyte" EXACT [PMID:23720296]
is_a: CL:1000488 {is_inferred="true"} ! cholangiocyte
intersection_of: CL:1000488 ! cholangiocyte
intersection_of: part_of UBERON:0004823 ! intrahepatic bile duct epithelium
relationship: part_of UBERON:0004823 ! intrahepatic bile duct epithelium
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-02-28T01:20:20Z

[Term]
id: CL:0002539
name: aortic smooth muscle cell
def: "A smooth muscle cell of the aorta." [GOC:tfm]
subset: cellxgene_subset
xref: BTO:0004577
is_a: CL:0019018 ! blood vessel smooth muscle cell
intersection_of: CL:0000359 ! vascular associated smooth muscle cell
intersection_of: part_of UBERON:0004178 ! aorta smooth muscle tissue
relationship: part_of UBERON:0004178 ! aorta smooth muscle tissue
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-02-28T01:42:12Z

[Term]
id: CL:0002540
name: mesenchymal stem cell of the bone marrow
def: "A mesenchymal stem cell that is part of the bone marrow." [GOC:tfm]
is_a: CL:0000134 ! mesenchymal stem cell
is_a: CL:0002092 ! bone marrow cell
intersection_of: CL:0000134 ! mesenchymal stem cell
intersection_of: part_of UBERON:0002371 ! bone marrow
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-02-28T01:47:47Z

[Term]
id: CL:0002541
name: chorionic membrane mesenchymal stem cell
def: "A mesenchymal stem cell of the chorionic membrane." [GOC:tfm]
subset: human_reference_atlas
is_a: CL:0000134 ! mesenchymal stem cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000134 ! mesenchymal stem cell
intersection_of: part_of UBERON:0003124 ! chorion membrane
relationship: part_of UBERON:0003124 ! chorion membrane
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2011-02-28T03:04:35Z

[Term]
id: CL:0002543
name: vein endothelial cell
def: "An endothelial cell that is part of the vein." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "endothelial cell of vein" EXACT []
synonym: "venous endothelial cell" EXACT []
xref: FMA:62104
xref: KUPO:0001099
is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell
intersection_of: CL:0000071 ! blood vessel endothelial cell
intersection_of: part_of UBERON:0001638 ! vein
relationship: part_of UBERON:0001638 ! vein
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2011-02-28T03:48:11Z

[Term]
id: CL:0002546
name: embryonic blood vessel endothelial progenitor cell
def: "An endothelial progenitor cell that participates in angiogenesis during development." [GOC:tfm]
comment: See CL:0002619.
is_a: CL:0000222 ! mesodermal cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-02-28T04:20:39Z

[Term]
id: CL:0002547
name: fibroblast of the aortic adventitia
def: "A fibroblast of the aortic adventitia." [GOC:tfm]
is_a: CL:1000306 {is_inferred="true"} ! fibroblast of tunica adventitia of artery
intersection_of: CL:1000306 ! fibroblast of tunica adventitia of artery
intersection_of: part_of UBERON:0004664 ! aorta tunica adventitia
relationship: part_of UBERON:0004664 ! aorta tunica adventitia
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-02-28T04:43:41Z

[Term]
id: CL:0002548
name: fibroblast of cardiac tissue
def: "A fibroblast that is part of the heart." [GOC:tfm]
subset: cellxgene_subset
synonym: "cardiac fibroblast" EXACT []
is_a: CL:0000057 {is_inferred="true"} ! fibroblast
is_a: CL:0002494 {is_inferred="true"} ! cardiocyte
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-02-28T04:57:44Z

[Term]
id: CL:0002551
name: fibroblast of dermis
is_a: CL:0002620 {is_inferred="true"} ! skin fibroblast
intersection_of: CL:0002620 ! skin fibroblast
intersection_of: part_of UBERON:0002067 ! dermis
relationship: part_of UBERON:0002067 ! dermis
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-02-28T05:05:33Z

[Term]
id: CL:0002553
name: fibroblast of lung
def: "A fibroblast that is part of lung." [GOC:tfm]
subset: cellxgene_subset
xref: BTO:0000764
xref: CALOHA:TS-0575
is_a: CL:0000057 {is_inferred="true"} ! fibroblast
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0002048 ! lung
relationship: part_of UBERON:0002048 ! lung
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-02-28T05:11:03Z

[Term]
id: CL:0002557
name: fibroblast of pulmonary artery
def: "A fibroblast of pulmonary artery." [GOC:tfm]
subset: human_reference_atlas
is_a: CL:0000057 {is_inferred="true"} ! fibroblast
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0002012 ! pulmonary artery
relationship: part_of UBERON:0002012 ! pulmonary artery
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2011-02-28T05:22:27Z

[Term]
id: CL:0002563
name: intestinal epithelial cell
def: "An epithelial cell of the intestine." [GOC:tfm]
subset: cellxgene_subset
is_a: CL:0002251 ! epithelial cell of alimentary canal
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0001277 ! intestinal epithelium
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-01T05:18:31Z

[Term]
id: CL:0002569
name: mesenchymal stem cell of umbilical cord
def: "A mesenchymal stem cell of the umbilical cord." [GOC:tfm]
is_a: CL:0000134 ! mesenchymal stem cell
is_a: CL:0000349 ! extraembryonic cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000134 ! mesenchymal stem cell
intersection_of: part_of UBERON:0003422 ! mesenchyme of umbilical cord
relationship: part_of UBERON:0003422 ! mesenchyme of umbilical cord
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-01T09:55:12Z

[Term]
id: CL:0002570
name: mesenchymal stem cell of adipose tissue
def: "A mesenchymal stem cell of adipose tissue." [GOC:tfm]
subset: cellxgene_subset
synonym: "mesenchymal stem cell of adipose" EXACT []
is_a: CL:0000134 ! mesenchymal stem cell
intersection_of: CL:0000134 ! mesenchymal stem cell
intersection_of: part_of UBERON:0001013 ! adipose tissue
relationship: part_of UBERON:0001013 ! adipose tissue
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-01T09:57:17Z

[Term]
id: CL:0002571
name: hepatic mesenchymal stem cell
def: "A mesenchymal stem cell of liver." [GOC:tfm]
is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell
is_a: CL:0002195 ! hepatic stem cell
intersection_of: CL:0000134 ! mesenchymal stem cell
intersection_of: part_of UBERON:0002107 ! liver
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-01T09:58:51Z

[Term]
id: CL:0002572
name: vertebral mesenchymal stem cell
def: "A mesenchymal stem cell of the vertebrae." [GOC:tfm]
is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell
is_a: CL:0001035 ! bone cell
intersection_of: CL:0000134 ! mesenchymal stem cell
intersection_of: part_of UBERON:0002412 ! vertebra
relationship: part_of UBERON:0002412 ! vertebra
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-01T10:40:27Z

[Term]
id: CL:0002574
name: stromal cell of pancreas
def: "A stromal cell of the pancreas." [GOC:tfm]
subset: human_reference_atlas
is_a: CL:0000499 {is_inferred="true"} ! stromal cell
intersection_of: CL:0000499 ! stromal cell
intersection_of: part_of UBERON:0001264 ! pancreas
relationship: part_of UBERON:0001264 ! pancreas
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2011-03-02T02:40:41Z

[Term]
id: CL:0002577
name: placental epithelial cell
def: "An epithelial cell of the placenta." [GOC:tfm]
is_a: CL:0000066 ! epithelial cell
is_a: CL:0000349 {is_inferred="true"} ! extraembryonic cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0001987 ! placenta
relationship: part_of UBERON:0001987 ! placenta
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-02T03:21:30Z

[Term]
id: CL:0002584
name: renal cortical epithelial cell
def: "An epithelial cell of the kidney cortex." [GOC:tfm]
xref: KUPO:0001016
is_a: CL:0002518 {is_inferred="true"} ! kidney epithelial cell
is_a: CL:0002681 {is_inferred="true"} ! kidney cortical cell
intersection_of: CL:0002518 ! kidney epithelial cell
intersection_of: part_of UBERON:0001225 ! cortex of kidney

[Term]
id: CL:0002585
name: retinal blood vessel endothelial cell
def: "A blood vessel endothelial cell that is part of the retina." [GOC:tfm]
subset: cellxgene_subset
subset: eye_upper_slim
subset: human_reference_atlas
is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell
is_a: CL:0009004 ! retinal cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000071 ! blood vessel endothelial cell
intersection_of: part_of UBERON:0000966 ! retina
relationship: part_of UBERON:0000966 ! retina
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2011-03-06T03:28:27Z

[Term]
id: CL:0002589
name: smooth muscle cell of the brachiocephalic vasculature
def: "A smooth muscle cell of the bachiocephalic vasculature." [GOC:tfm]
is_a: CL:0019018 ! blood vessel smooth muscle cell
intersection_of: CL:0000359 ! vascular associated smooth muscle cell
intersection_of: part_of UBERON:0001529 ! brachiocephalic artery
relationship: part_of UBERON:0001529 ! brachiocephalic artery
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-06T05:00:58Z

[Term]
id: CL:0002590
name: smooth muscle cell of the brain vasculature
def: "A vascular associated smooth muscle cell of the brain vasculature." [GOC:tfm]
is_a: CL:0000359 {is_inferred="true"} ! vascular associated smooth muscle cell
is_a: CL:0002319 ! neural cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000359 ! vascular associated smooth muscle cell
intersection_of: part_of UBERON:0000955 ! brain
relationship: part_of UBERON:0000955 ! brain
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-06T05:01:20Z

[Term]
id: CL:0002591
name: smooth muscle cell of the pulmonary artery
def: "A smooth muscle of the pulmonary artery." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
xref: BTO:0003336
is_a: CL:0019018 ! blood vessel smooth muscle cell
intersection_of: CL:0000359 ! vascular associated smooth muscle cell
intersection_of: part_of UBERON:0002012 ! pulmonary artery
relationship: part_of UBERON:0002012 ! pulmonary artery
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2011-03-06T05:01:28Z

[Term]
id: CL:0002594
name: smooth muscle cell of the umbilical artery
def: "A smooth muscle cell of the umbilical artery." [GOC:tfm]
is_a: CL:0019018 ! blood vessel smooth muscle cell
intersection_of: CL:0000359 ! vascular associated smooth muscle cell
intersection_of: part_of UBERON:0001310 ! umbilical artery
relationship: part_of UBERON:0001310 ! umbilical artery
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-06T05:01:48Z

[Term]
id: CL:0002595
name: smooth muscle cell of the subclavian artery
def: "A smooth muscle cell of the subclavian artery." [GOC:tfm]
is_a: CL:0019018 ! blood vessel smooth muscle cell
intersection_of: CL:0000359 ! vascular associated smooth muscle cell
intersection_of: part_of UBERON:0001533 ! subclavian artery
relationship: part_of UBERON:0001533 ! subclavian artery
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-06T05:01:52Z

[Term]
id: CL:0002596
name: smooth muscle cell of the carotid artery
def: "Smooth muscle cell of the carotid artery." [GOC:tfm]
is_a: CL:0019018 ! blood vessel smooth muscle cell
intersection_of: CL:0000359 ! vascular associated smooth muscle cell
intersection_of: part_of UBERON:0005396 ! carotid artery segment
relationship: part_of UBERON:0005396 ! carotid artery segment
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-06T05:01:56Z

[Term]
id: CL:0002597
name: smooth muscle cell of bladder
def: "A smooth muscle cell of the bladder." [GC:tfm]
subset: human_reference_atlas
xref: KUPO:0001122
is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell
is_a: CL:1001319 ! bladder cell
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0001255 ! urinary bladder
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2011-03-06T05:43:24Z

[Term]
id: CL:0002599
name: smooth muscle cell of the esophagus
def: "A smooth muscle cell of the esophagus." [GOC:tfm]
is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001043 ! esophagus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-06T05:48:17Z

[Term]
id: CL:0002601
name: uterine smooth muscle cell
def: "A smooth muscle cell of the uterus." [GOC:tfm]
subset: cellxgene_subset
is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0000995 ! uterus
relationship: part_of UBERON:0000995 ! uterus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-06T05:53:28Z

[Term]
id: CL:0002610
name: raphe nuclei neuron
def: "A neuron of the raphe nuclei." [GOC:tfm]
is_a: CL:0000117 {is_inferred="true"} ! CNS neuron (sensu Vertebrata)
is_a: CL:2000029 ! central nervous system neuron
intersection_of: CL:0000117 ! CNS neuron (sensu Vertebrata)
intersection_of: has_soma_location UBERON:0004684 ! raphe nuclei
relationship: has_soma_location UBERON:0004684 ! raphe nuclei
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-06T07:42:06Z

[Term]
id: CL:0002612
name: neuron of the ventral spinal cord
def: "A neuron of the ventral spinal cord." [GOC:tfm]
is_a: CL:0000117 {is_inferred="true"} ! CNS neuron (sensu Vertebrata)
is_a: CL:2000029 ! central nervous system neuron
intersection_of: CL:0000117 ! CNS neuron (sensu Vertebrata)
intersection_of: has_soma_location UBERON:0002257 ! ventral horn of spinal cord
relationship: has_soma_location UBERON:0002257 ! ventral horn of spinal cord
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-06T07:46:03Z

[Term]
id: CL:0002620
name: skin fibroblast
def: "A fibroblast of skin." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
xref: BTO:0001255
xref: CALOHA:TS-0935
is_a: CL:0000057 {is_inferred="true"} ! fibroblast
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0002097 ! skin of body
relationship: part_of UBERON:0002097 ! skin of body
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2011-03-14T12:31:49Z

[Term]
id: CL:0002625
name: seminiferous tubule epithelial cell
def: "A cell of the seminiferous tubule epithelium." [GOC:tfm]
is_a: CL:0000068 ! duct epithelial cell
is_a: CL:0000077 {is_inferred="true"} ! mesothelial cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0001343 ! seminiferous tubule of testis
relationship: part_of UBERON:0004813 ! seminiferous tubule epithelium
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-03-15T11:59:23Z

[Term]
id: CL:0002632
name: epithelial cell of lower respiratory tract
subset: cellxgene_subset
is_a: CL:0002368 {is_inferred="true"} ! respiratory epithelial cell
intersection_of: CL:0002368 ! respiratory epithelial cell
intersection_of: part_of UBERON:0001558 ! lower respiratory tract
relationship: part_of UBERON:0001558 ! lower respiratory tract
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-06-21T12:29:31Z

[Term]
id: CL:0002656
name: glandular cell of endometrium
def: "A glandular epithelial cell of the endometrium." [GOC:tfm]
xref: FMA:86489
is_a: CL:1001591 ! oviduct glandular cell
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0001295 ! endometrium
relationship: part_of UBERON:0001295 ! endometrium
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-07-08T03:54:08Z

[Term]
id: CL:0002657
name: glandular cell of esophagus
def: "A glandular epithelial cell of the esophagus." [GOC:tfm]
subset: cellxgene_subset
xref: FMA:86548
is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell
is_a: CL:0002252 {is_inferred="true"} ! epithelial cell of esophagus
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0001043 ! esophagus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-07-08T03:55:57Z

[Term]
id: CL:0002658
name: glandular cell of the large intestine
def: "A glandular epithelial cell of the large intestine." [GOC:tfm]
xref: FMA:87194
is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell
is_a: CL:0002253 ! epithelial cell of large intestine
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0000059 ! large intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-07-08T04:03:01Z

[Term]
id: CL:0002659
name: glandular cell of stomach
def: "A glandular epithelial cell that is part of the stomach." [GOC:tfm]
xref: CALOHA:TS-1284
xref: FMA:86554
is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell
is_a: CL:0002178 ! epithelial cell of stomach
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0000945 ! stomach
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-07-11T01:20:35Z

[Term]
id: CL:0002663
name: myocardial endocrine cell of atrium
def: "A myocardial endocrine cell that is part of the atrium." [GOC:tfm]
xref: FMA:83389
is_a: CL:0002074 {is_inferred="true"} ! myocardial endocrine cell
intersection_of: CL:0002074 ! myocardial endocrine cell
intersection_of: part_of UBERON:0002081 ! cardiac atrium
relationship: part_of UBERON:0002081 ! cardiac atrium
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-07-11T02:45:39Z

[Term]
id: CL:0002664
name: cardioblast
def: "A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart." [GOC:tfm, PMID:19745164]
comment: Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell.
synonym: "cardiovascular progenitor cell" EXACT [PMID:17519333, PMID:19745164]
synonym: "CPC" RELATED OMO:0003000 [PMID:19745164]
is_a: CL:0000048 ! multi fate stem cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-07-11T03:15:38Z

[Term]
id: CL:0002672
name: retinal progenitor cell
def: "A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells." [GOC:tfm, PMID:20959166, PMID:21148186]
is_a: CL:0000048 ! multi fate stem cell
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: develops_from CL:0000133 ! neurectodermal cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-08-16T02:38:01Z

[Term]
id: CL:0002676
name: neural crest derived neuroblast
def: "A neuroblast derived from a neural crest cell." [GOC:tfm, PMID:17407019]
is_a: CL:0000031 ! neuroblast (sensu Vertebrata)
is_a: CL:0011026 ! progenitor cell
is_a: UBERON:0010313 ! neural crest-derived structure
relationship: develops_from CL:0000333 ! migratory neural crest cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-08-22T09:24:15Z

[Term]
id: CL:0002680
name: PP cell of intestine
def: "A PP cell found in intestine." [GOC:tfm, PMID:2420136, PMID:728970]
is_a: CL:0000696 {is_inferred="true"} ! PP cell
is_a: CL:1001516 ! intestinal enteroendocrine cell
intersection_of: CL:0000696 ! PP cell
intersection_of: part_of UBERON:0000160 ! intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2011-09-27T11:59:01Z

[Term]
id: CL:0002681
name: kidney cortical cell
def: "A cell that is part of a cortex of kidney." []
is_a: CL:1000497 ! kidney cell
intersection_of: CL:1000497 ! kidney cell
intersection_of: part_of UBERON:0001225 ! cortex of kidney
relationship: part_of UBERON:0001225 ! cortex of kidney
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0956-8634
creation_date: 2011-10-25T03:49:41Z

[Term]
id: CL:0005000
name: spinal cord interneuron
def: "A CNS interneuron located in the spinal cord." [CL:CVS]
comment: Is_a interneuron, part_of UBERON:0002240.
is_a: CL:0000402 {is_inferred="true"} ! CNS interneuron
intersection_of: CL:0000099 ! interneuron
intersection_of: has_soma_location UBERON:0002240 ! spinal cord
relationship: has_soma_location UBERON:0002240 ! spinal cord

[Term]
id: CL:0005009
name: renal principal cell
def: "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system." [CL:CVS]
subset: cellxgene_subset
is_a: CL:0000075 ! columnar/cuboidal epithelial cell
is_a: CL:0002518 ! kidney epithelial cell

[Term]
id: CL:0005024
name: somatomotor neuron
def: "A motor neuron that innervates a skeletal muscle.  These motor neurons are all excitatory and cholinergic." [ZFIN:CVS]
synonym: "somatic motor neuron" EXACT []
is_a: CL:0000100 ! motor neuron
is_a: CL:0000108 ! cholinergic neuron
intersection_of: CL:0000100 ! motor neuron
intersection_of: synapsed_to CL:0008002 ! skeletal muscle fiber
relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: part_of RO:0002577 ! system
relationship: synapsed_to CL:0008002 ! skeletal muscle fiber

[Term]
id: CL:0005026
name: hepatoblast
def: "Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation." [GOC:CVS, https://orcid.org/0000-0003-1940-6740, PMID:18356246, PMID:20483998, PMID:26798363]
subset: cellxgene_subset
is_a: CL:0000048 ! multi fate stem cell
property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" xsd:string

[Term]
id: CL:0007001
name: skeletogenic cell
def: "Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized)." [GO_REF:0000034]
comment: Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts)
synonym: "scleroblast" EXACT [GO_REF:0000034]
is_a: CL:0000000 ! cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-9114-8737
creation_date: 2012-06-15T02:51:27Z

[Term]
id: CL:0007004
name: premigratory neural crest cell
def: "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells." [UBERONREF:0000002]
is_a: CL:0011012 ! neural crest cell
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: develops_from CL:0000133 ! neurectodermal cell
relationship: part_of UBERON:0002342 ! neural crest
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-9114-8737
creation_date: 2012-06-27T08:27:35Z

[Term]
id: CL:0007009
name: prechondroblast
def: "Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells." [GO_REF:0000034]
is_a: CL:0000055 ! non-terminally differentiated cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-9114-8737
creation_date: 2012-06-27T10:44:01Z

[Term]
id: CL:0008000
name: non-striated muscle cell
def: "Any muscle cell in which the fibers are not organised into sarcomeres." [GOC:DOS]
is_a: CL:0000187 ! muscle cell

[Term]
id: CL:0008001
name: hematopoietic precursor cell
def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos]
subset: cellxgene_subset
is_a: CL:0000988 ! hematopoietic cell

[Term]
id: CL:0008002
name: skeletal muscle fiber
def: "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:tfm, ISBN:0323052908]
subset: cellxgene_subset
xref: MESH:D018485
is_a: CL:0000188 ! cell of skeletal muscle
is_a: CL:0002372 ! myotube
intersection_of: CL:0000187 ! muscle cell
intersection_of: has_characteristic PATO:0001908 ! multinucleate
intersection_of: has_characteristic PATO:0002478 ! transversely striated
intersection_of: has_part GO:0030017 ! sarcomere
intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue
relationship: develops_from CL:0000515 ! skeletal muscle myoblast

[Term]
id: CL:0008007
name: visceral muscle cell
def: "A muscle cell that is part of some visceral muscle." [GOC:dos]
xref: FBbt:00005070
is_a: CL:0000187 ! muscle cell
intersection_of: CL:0000187 ! muscle cell
intersection_of: part_of UBERON:8600004 ! visceral muscle tissue
relationship: part_of UBERON:8600004 ! visceral muscle tissue

[Term]
id: CL:0008008
name: striated visceral muscle cell
def: "A visceral muscle cell that is striated.  Examples include the visceral muscle cells of arhtropods." [GOC:dos]
is_a: CL:0000737 ! striated muscle cell
is_a: CL:0008007 ! visceral muscle cell
intersection_of: CL:0008007 ! visceral muscle cell
intersection_of: has_characteristic PATO:0001410 {all_some="true"} ! striated

[Term]
id: CL:0008009
name: transversely striated visceral muscle cell
def: "A visceral muscle that is transversely striated.  Examples include the visceral muscle cells of arthropods." [GOC:dos]
is_a: CL:0008008 ! striated visceral muscle cell
intersection_of: CL:0008007 ! visceral muscle cell
intersection_of: has_characteristic PATO:0002478 {all_some="true"} ! transversely striated
relationship: has_characteristic PATO:0002478 ! transversely striated

[Term]
id: CL:0008017
name: adult skeletal muscle myoblast
def: "A skeletal muscle myoblast that is part of a skeletal mucle.  These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers." [PMID:23303905]
comment: The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins.
synonym: "myogenic precursor cell" BROAD [PMID:23303905]
is_a: CL:0000188 ! cell of skeletal muscle
is_a: CL:0000515 ! skeletal muscle myoblast
intersection_of: CL:0000056 ! myoblast
intersection_of: develops_into CL:0008002 ! skeletal muscle fiber
intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue

[Term]
id: CL:0008019
name: mesenchymal cell
def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." []
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "mesenchyme cell" EXACT []
is_a: CL:0000219 ! motile cell
relationship: capable_of GO:0016477 ! cell migration
relationship: part_of UBERON:0003104 ! mesenchyme
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0008022
name: endocardial cushion cell
def: "A mesenchymal cell of the endocardial cushion.   These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves." [PMID:18816864]
is_a: CL:0000569 ! cardiac mesenchymal cell
is_a: CL:0002494 ! cardiocyte
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000569 ! cardiac mesenchymal cell
intersection_of: part_of UBERON:0002062 ! endocardial cushion
relationship: part_of UBERON:0002062 ! endocardial cushion

[Term]
id: CL:0008024
name: pancreatic endocrine cell
def: "An endocrine cell that is part of the pancreas." [GOC:dos]
subset: cellxgene_subset
subset: human_reference_atlas
is_a: CL:0000083 ! epithelial cell of pancreas
is_a: CL:0000164 ! enteroendocrine cell
intersection_of: CL:0000163 ! endocrine cell
intersection_of: part_of UBERON:0001264 ! pancreas
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0008025
name: noradrenergic neuron
def: "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter." [GOC:dos]
is_a: CL:0000459 ! noradrenergic cell
is_a: CL:4033050 ! catecholaminergic neuron
intersection_of: CL:0000540 ! neuron
intersection_of: capable_of GO:0061533 ! norepinephrine secretion, neurotransmission
relationship: capable_of GO:0061533 ! norepinephrine secretion, neurotransmission

[Term]
id: CL:0008028
name: visual system neuron
is_a: CL:0000540 ! neuron
intersection_of: CL:0000540 ! neuron
intersection_of: capable_of_part_of GO:0007601 ! visual perception
relationship: capable_of_part_of GO:0007601 ! visual perception
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-7073-9172
creation_date: 2017-07-09T19:12:36Z

[Term]
id: CL:0008034
name: mural cell
def: "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." [Wiki:Mural_cell&oldid=930603194]
subset: added_for_HCA
subset: cellxgene_subset
subset: human_reference_atlas
is_a: CL:4033054 ! perivascular cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-7073-9172
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2020-02-29T17:33:55Z

[Term]
id: CL:0008035
name: microcirculation associated smooth muscle cell
is_a: CL:0000359 ! vascular associated smooth muscle cell
is_a: CL:0008034 ! mural cell
intersection_of: CL:0000359 ! vascular associated smooth muscle cell
intersection_of: part_of UBERON:0010523 ! microcirculatory vessel
relationship: part_of UBERON:0010523 ! microcirculatory vessel
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-7073-9172
creation_date: 2020-02-29T17:37:00Z

[Term]
id: CL:0009000
name: sensory neuron of spinal nerve
def: "A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord." [GOC:nv, GOC:pr]
synonym: "spinal sensory neuron" EXACT []
is_a: CL:3000004 ! peripheral sensory neuron
intersection_of: CL:0000101 ! sensory neuron
intersection_of: has_soma_location UBERON:0001780 ! spinal nerve
relationship: has_soma_location UBERON:0001780 ! spinal nerve

[Term]
id: CL:0009001
name: compound eye retinal cell
def: "Any cell in the compound eye, a light sensing organ composed of ommatidia." []
xref: GOC:pr
xref: PMID:12021768
is_a: CL:0009004 ! retinal cell

[Term]
id: CL:0009004
name: retinal cell
def: "Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:pr]
subset: general_cell_types_upper_slim
xref: PMID:10702418
is_a: CL:0002319 ! neural cell
intersection_of: CL:0002319 ! neural cell
intersection_of: part_of UBERON:0005388 ! photoreceptor array
relationship: part_of UBERON:0005388 ! photoreceptor array

[Term]
id: CL:0009006
name: enteroendocrine cell of small intestine
def: "An enteroendocrine cell that is located in the small intestine." [http://orcid.org/0000-0003-3440-1876]
subset: cellxgene_subset
subset: location_grouping
synonym: "small intestine enteroendocrine cell" EXACT []
is_a: CL:1001516 ! intestinal enteroendocrine cell
is_a: CL:1001598 ! small intestine glandular cell
intersection_of: CL:0000164 ! enteroendocrine cell
intersection_of: part_of UBERON:0002108 ! small intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009018
name: lymphocyte of large intestine lamina propria
def: "A lymphocyte that resides in the lamina propria of the large intestine." [https://orcid.org/0000-0003-4183-8865]
comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.
subset: human_reference_atlas
subset: location_grouping
synonym: "lamina propria lymphocyte of large intestine" EXACT []
is_a: CL:0000542 ! lymphocyte
intersection_of: CL:0000542 ! lymphocyte
intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine
relationship: part_of UBERON:0011189 ! lamina propria of large intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0009019
name: nephrogenic zone cell
def: "A kidney cortical cell that is part of the nephrogenic zone." [https://orcid.org/0000-0002-3163-0115, PMID:29449449]
subset: added_for_HCA
synonym: "cortical nephrogenic niche cell" EXACT []
synonym: "cortical nephrogenic zone cell" EXACT []
is_a: CL:0002681 ! kidney cortical cell
intersection_of: CL:0002681 ! kidney cortical cell
intersection_of: part_of UBERON:0009871 ! nephrogenic zone
relationship: part_of UBERON:0009871 ! nephrogenic zone
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009021
name: stromal cell of lamina propria of large intestine
def: "A stromal cell found in the lamina propria of the large intestine." [http://orcid.org/0000-0003-4183-8865]
subset: location_grouping
is_a: CL:0000499 ! stromal cell
intersection_of: CL:0000499 ! stromal cell
intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine
relationship: part_of UBERON:0011189 ! lamina propria of large intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009022
name: stromal cell of lamina propria of small intestine
def: "A stromal cell found in the lamina propria of the small intestine." [http://orcid.org/0000-0003-4183-8865]
subset: cellxgene_subset
subset: location_grouping
is_a: CL:0000499 ! stromal cell
intersection_of: CL:0000499 ! stromal cell
intersection_of: part_of UBERON:0001238 ! lamina propria of small intestine
relationship: part_of UBERON:0001238 ! lamina propria of small intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009024
name: mesothelial cell of small intestine
def: "A mesothelial cell that is part of the small intestine." [http://orcid.org/0000-0003-4183-8865]
subset: location_grouping
is_a: CL:0000077 ! mesothelial cell
is_a: CL:0002254 ! epithelial cell of small intestine
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: CL:0000077 ! mesothelial cell
intersection_of: part_of UBERON:0002108 ! small intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009025
name: mesothelial cell of colon
def: "A mesothelial cell that is part of the colon." [http://orcid.org/0000-0003-3440-1876, http://orcid.org/0000-0003-4183-8865]
subset: location_grouping
synonym: "mesothelial cell of large intestine" BROAD []
is_a: CL:0000077 ! mesothelial cell
is_a: CL:0011108 ! colon epithelial cell
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: CL:0000077 ! mesothelial cell
intersection_of: part_of UBERON:0001155 ! colon
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009040
name: stromal cell of lamina propria of colon
def: "A stromal cell found in the lamina propria of the colon." [http://orcid.org/0000-0003-3440-1876]
subset: location_grouping
synonym: "stromal cell of colon lamina propria" EXACT []
is_a: CL:0009021 ! stromal cell of lamina propria of large intestine
intersection_of: CL:0000499 ! stromal cell
intersection_of: part_of UBERON:0007177 ! lamina propria of mucosa of colon
relationship: part_of UBERON:0007177 ! lamina propria of mucosa of colon
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009042
name: enteroendocrine cell of colon
def: "An enteroendocrine cell that is located in the colon." [http://orcid.org/0000-0003-3440-1876]
subset: cellxgene_subset
subset: location_grouping
synonym: "colon enteroendocrine cell" EXACT []
is_a: CL:1001516 ! intestinal enteroendocrine cell
is_a: CL:1001588 ! colon glandular cell
intersection_of: CL:0000164 ! enteroendocrine cell
intersection_of: part_of UBERON:0001155 ! colon
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009044
name: lymphocyte of small intestine lamina propria
def: "A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response." [https://orcid.org/0000-0003-4183-8865, PMID:26551552]
comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.
subset: location_grouping
synonym: "gastrointestinal tract (lamina propria) lymphocyte of small intestine" EXACT []
synonym: "gastrointestinal tract small intestine (lamina propria) leukocyte" BROAD []
synonym: "lamina propria lymphocyte of small intestine" EXACT []
synonym: "small intestine lamina propria leukocyte" BROAD []
synonym: "small intestine lamina propria leukocyte (LPL)" BROAD []
synonym: "small intestine lamina propria lymphocyte" EXACT []
is_a: CL:0000542 ! lymphocyte
intersection_of: CL:0000542 ! lymphocyte
intersection_of: part_of UBERON:0001238 ! lamina propria of small intestine
relationship: part_of UBERON:0001238 ! lamina propria of small intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009051
name: T cell of anorectum
def: "A T cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876]
comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.
subset: location_grouping
is_a: CL:0000084 ! T cell
intersection_of: CL:0000084 ! T cell
intersection_of: part_of UBERON:8410050 ! anorectum
relationship: part_of UBERON:8410050 ! anorectum
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009052
name: smooth muscle cell of anorectum
def: "A smooth muscle cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876]
subset: location_grouping
synonym: "anorectum smooth muscle cell" EXACT []
is_a: CL:1000279 ! smooth muscle cell of large intestine
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:8410050 ! anorectum
relationship: part_of UBERON:8410050 ! anorectum
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009053
name: stromal cell of anorectum lamina propria
def: "A stromal cell found in the lamina propria of the anorectum." [http://orcid.org/0000-0003-3440-1876]
subset: location_grouping
is_a: CL:0009021 ! stromal cell of lamina propria of large intestine
intersection_of: CL:0000499 ! stromal cell
intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine
intersection_of: part_of UBERON:8410050 ! anorectum
relationship: part_of UBERON:8410050 ! anorectum
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009063
name: enteroendocrine cell of anorectum
def: "An enteroendocrine cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876]
subset: location_grouping
synonym: "anorectum enteroendocrine cell" EXACT []
is_a: CL:0002658 ! glandular cell of the large intestine
is_a: CL:1001516 ! intestinal enteroendocrine cell
intersection_of: CL:0000164 ! enteroendocrine cell
intersection_of: part_of UBERON:8410050 ! anorectum
relationship: part_of UBERON:8410050 ! anorectum
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: CL:0009084
name: epithelial cell of endometrial gland
def: "An epithelial cell that is part of an endometrial gland." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865]
subset: human_reference_atlas
subset: location_grouping
synonym: "endometrial glandular epithelial cell" EXACT []
xref: EFO:0010710
is_a: CL:0000066 ! epithelial cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0002451 ! endometrial gland
relationship: part_of UBERON:0002451 ! endometrial gland
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: http://purl.org/dc/terms/date "2021-11-30T16:13:30Z" xsd:dateTime
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0009092
name: endothelial cell of placenta
def: "An endothelial cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865]
subset: cellxgene_subset
subset: location_grouping
synonym: "placental endothelial cell" EXACT []
xref: EFO:0010708
is_a: CL:0000115 ! endothelial cell
is_a: CL:0002577 ! placental epithelial cell
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0001987 ! placenta
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: http://purl.org/dc/terms/date "2021-12-13T13:53:01Z" xsd:dateTime

[Term]
id: CL:0009093
name: smooth muscle cell of placenta
def: "A smooth muscle cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865]
subset: location_grouping
synonym: "placental smooth muscle cell" EXACT []
xref: EFO:0010709
is_a: CL:0000192 ! smooth muscle cell
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0001987 ! placenta
relationship: part_of UBERON:0001987 ! placenta
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: http://purl.org/dc/terms/date "2021-12-13T13:56:42Z" xsd:dateTime

[Term]
id: CL:0009094
name: endothelial cell of hepatic portal vein
def: "An endothelial cell that is part of a hepatic portal vein." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865, PMID:30348985]
subset: location_grouping
synonym: "portal endothelial cell" BROAD []
xref: EFO:0010704
is_a: CL:0000115 ! endothelial cell
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0001639 ! hepatic portal vein
relationship: part_of UBERON:0001639 ! hepatic portal vein
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: http://purl.org/dc/terms/date "2021-12-13T14:01:05Z" xsd:dateTime

[Term]
id: CL:0009095
name: endothelial cell of uterus
def: "An endothelial cell that is part of a uterus." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865]
subset: cellxgene_subset
subset: location_grouping
synonym: "uterine endothelial cell" EXACT []
xref: EFO:0010711
is_a: CL:0000115 ! endothelial cell
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0000995 ! uterus
relationship: part_of UBERON:0000995 ! uterus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: http://purl.org/dc/terms/date "2021-12-13T14:39:25Z" xsd:dateTime

[Term]
id: CL:0009097
name: embryonic skeletal muscle fiber
def: "A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development." [http://orcid.org/0000-0003-2034-601X, PMID:32094117, PMID:7196501]
is_a: CL:0008002 ! skeletal muscle fiber
intersection_of: CL:0008002 ! skeletal muscle fiber
intersection_of: existence_starts_and_ends_during UBERON:0000068 ! embryo stage
relationship: existence_starts_and_ends_during UBERON:0000068 ! embryo stage
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: http://purl.org/dc/terms/date "2022-02-21T15:39:10Z" xsd:dateTime

[Term]
id: CL:0009100
name: hepatic portal fibroblast
def: "A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen." [https://orcid.org/0000-0001-7655-4833, PMID:20209607, PMID:24814904]
subset: human_reference_atlas
synonym: "portal fibroblast" BROAD []
is_a: CL:0000057 ! fibroblast
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0001279 ! portal triad
relationship: part_of UBERON:0001279 ! portal triad
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: http://purl.org/dc/terms/date "2022-03-17T12:00:44Z" xsd:dateTime
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0010001
name: stromal cell of bone marrow
def: "A stromal cell that is part_of a bone marrow." []
synonym: "bone marrow stromal cell" EXACT []
is_a: CL:0000499 ! stromal cell
is_a: CL:0002092 ! bone marrow cell
intersection_of: CL:0000499 ! stromal cell
intersection_of: part_of UBERON:0002371 ! bone marrow
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-6601-2165

[Term]
id: CL:0010002
name: epithelial cell of umbilical artery
def: "An epithelial cell that is part_of a umbilical artery." []
synonym: "umbilical artery epithelial cell" EXACT []
is_a: CL:0000066 ! epithelial cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0001310 ! umbilical artery
relationship: part_of UBERON:0001310 ! umbilical artery
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-6601-2165

[Term]
id: CL:0010004
name: mononuclear cell of bone marrow
def: "A mononuclear cell that is part_of a bone marrow." []
synonym: "bone marrow mononuclear cell" EXACT []
is_a: CL:0000842 ! mononuclear cell
is_a: CL:1001610 ! bone marrow hematopoietic cell
intersection_of: CL:0000842 ! mononuclear cell
intersection_of: part_of UBERON:0002371 ! bone marrow
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-6601-2165

[Term]
id: CL:0010006
name: cardiac blood vessel endothelial cell
is_a: CL:0000071 ! blood vessel endothelial cell
is_a: CL:0010008 ! cardiac endothelial cell
intersection_of: CL:0000071 ! blood vessel endothelial cell
intersection_of: part_of UBERON:0000948 ! heart

[Term]
id: CL:0010007
name: His-Purkinje system cell
is_a: CL:0002494 ! cardiocyte
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0004146 ! His-Purkinje system
relationship: part_of UBERON:0004146 ! His-Purkinje system

[Term]
id: CL:0010008
name: cardiac endothelial cell
subset: cellxgene_subset
subset: human_reference_atlas
is_a: CL:0000115 ! endothelial cell
is_a: CL:0002494 ! cardiocyte
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0010009
name: camera-type eye photoreceptor cell
synonym: "camera type eye photoreceptor cell" EXACT []
is_a: CL:0000287 ! eye photoreceptor cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000210 ! photoreceptor cell
intersection_of: part_of UBERON:0000019 ! camera-type eye
relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: part_of UBERON:0000019 ! camera-type eye

[Term]
id: CL:0010017
name: zygote
def: "A zygote in a plant or an animal." []
xref: MESH:D015053
is_a: CL:0000000 ! cell
relationship: seeAlso https://github.com/obophenotype/cell-ontology/issues/786

[Term]
id: CL:0010020
name: cardiac glial cell
is_a: CL:0000125 ! glial cell
is_a: CL:0002494 ! cardiocyte
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000125 ! glial cell
intersection_of: part_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart

[Term]
id: CL:0010021
name: cardiac myoblast
xref: MESH:D032386
is_a: CL:0000056 ! myoblast
intersection_of: CL:0000056 ! myoblast
intersection_of: develops_into CL:0000746 ! cardiac muscle cell
relationship: develops_into CL:0000746 ! cardiac muscle cell

[Term]
id: CL:0010022
name: cardiac neuron
def: "A neuron that has its soma in the heart." [PMID:12486170, PMID:29265764]
comment: This term is used in 3 GO terms that were created as part of the heart development focus project.
subset: cellxgene_subset
is_a: CL:0000540 ! neuron
intersection_of: CL:0000540 ! neuron
intersection_of: has_soma_location UBERON:0000948 ! heart
relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: has_soma_location UBERON:0000948 ! heart
property_value: seeAlso "https://github.com/obophenotype/cell-ontology/pull/1488" xsd:string

[Term]
id: CL:0011001
name: spinal cord motor neuron
def: "A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [GOC:nv]
is_a: CL:0000100 {is_inferred="true"} ! motor neuron
is_a: CL:2000029 ! central nervous system neuron
intersection_of: CL:0000100 ! motor neuron
intersection_of: has_soma_location UBERON:0002240 ! spinal cord
relationship: has_soma_location UBERON:0002240 ! spinal cord

[Term]
id: CL:0011007
name: paraxial cell
def: "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites." [GOC:NV, PMID:11687492]
synonym: "paraxial mesoderm cell" EXACT []
synonym: "presomitic mesoderm cell" NARROW []
synonym: "somitic mesoderm cell" EXACT []
is_a: CL:0000222 ! mesodermal cell
intersection_of: CL:0000222 ! mesodermal cell
intersection_of: part_of UBERON:0003059 ! presomitic mesoderm
relationship: part_of UBERON:0003059 ! presomitic mesoderm

[Term]
id: CL:0011012
name: neural crest cell
def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880]
subset: cellxgene_subset
is_a: CL:0000048 ! multi fate stem cell
is_a: CL:0002321 ! embryonic cell (metazoa)

[Term]
id: CL:0011013
name: motile sperm cell
def: "A sperm cell that is cabaple of motion (motility)." [PMID:30612620]
is_a: CL:0000019 ! sperm
is_a: CL:0000219 ! motile cell
intersection_of: CL:0000019 ! sperm
intersection_of: capable_of GO:0097722 ! sperm motility
relationship: capable_of GO:0097722 ! sperm motility
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: CL:0011016
name: flagellated sperm cell
def: "A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion." [https://www.lexico.com/en/definition/flagellum, PMID:30612620]
is_a: CL:0011013 ! motile sperm cell
intersection_of: CL:0011013 ! motile sperm cell
intersection_of: capable_of GO:0030317 ! flagellated sperm motility
relationship: capable_of GO:0030317 ! flagellated sperm motility
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: CL:0011019
name: mesothelial cell of epicardium
def: "A mesothelial cell that is part of the epicardium." []
subset: cellxgene_subset
is_a: CL:0000077 ! mesothelial cell
is_a: CL:0002494 ! cardiocyte
intersection_of: CL:0000077 ! mesothelial cell
intersection_of: part_of UBERON:0002348 ! epicardium
relationship: part_of UBERON:0002348 ! epicardium
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: CL:0011021
name: fibroblast of upper back skin
def: "A fibroblast that is part of upper back skin." []
is_a: CL:0011022 ! fibroblast of skin of back
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0009015 ! upper back skin
relationship: part_of UBERON:0009015 ! upper back skin
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: CL:0011022
name: fibroblast of skin of back
def: "A fibroblast that is part of skin of back." []
is_a: CL:0002620 ! skin fibroblast
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0001068 ! skin of back
relationship: part_of UBERON:0001068 ! skin of back
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: CL:0011026
name: progenitor cell
def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3]
subset: cellxgene_subset
is_a: CL:0011115 ! precursor cell
intersection_of: CL:0011115 ! precursor cell
intersection_of: develops_from CL:0000034 ! stem cell
relationship: develops_from CL:0000034 ! stem cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: CL:0011027
name: skeletal muscle fibroblast
def: "Any fibroblast that is part of skeletal muscle tissue." [https://orcid.org/0000-0001-6164-0667, PMID:28369879]
subset: cellxgene_subset
synonym: "skeleton muscle fibroblast" EXACT []
is_a: CL:0000188 ! cell of skeletal muscle
is_a: CL:1001609 ! muscle fibroblast
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: CL:0011030
name: dermal microvascular endothelial cell
def: "Any microvascular endothelial cell that is part of the dermis." [BTO:0004574, CL:patterns/cellPartOfAnatomicalEntity]
synonym: "dermal microvascular endothelium cell" EXACT []
synonym: "DMEC cell" EXACT []
is_a: CL:2000008 ! microvascular endothelial cell
is_a: CL:2000010 ! dermis blood vessel endothelial cell
intersection_of: CL:2000008 ! microvascular endothelial cell
intersection_of: part_of UBERON:0002067 ! dermis
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: CL:0011101
name: chorionic trophoblast cell
def: "Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [GOC:NV]
subset: cellxgene_subset
is_a: CL:0000351 ! trophoblast cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000351 ! trophoblast cell
intersection_of: part_of UBERON:0003124 ! chorion membrane
relationship: part_of UBERON:0003124 ! chorion membrane

[Term]
id: CL:0011108
name: colon epithelial cell
def: "Epithelial cell that is part of the colon epithelium." [GOC:NV]
subset: cellxgene_subset
synonym: "colonic epithelial cell" EXACT []
is_a: CL:0002253 ! epithelial cell of large intestine
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0000397 ! colonic epithelium

[Term]
id: CL:0011115
name: precursor cell
def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos]
comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell.
subset: cellxgene_subset
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: capable_of GO:0030154 ! cell differentiation
relationship: capable_of GO:0030154 ! cell differentiation

[Term]
id: CL:0017500
name: neutrophillic cytoplasm
def: "Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain." [GOC:add]
is_a: GO:0005737 ! cytoplasm
intersection_of: GO:0005737 ! cytoplasm
intersection_of: has_characteristic PATO:0070046 ! neutrophillic
relationship: has_characteristic PATO:0070046 ! neutrophillic
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2010-05-25T01:36:34Z

[Term]
id: CL:0017502
name: acidophilic cytoplasm
def: "Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain." [GOC:add]
synonym: "eosinophilic" NARROW []
is_a: GO:0005737 ! cytoplasm
intersection_of: GO:0005737 ! cytoplasm
intersection_of: has_characteristic PATO:0002418 ! acidophilic
relationship: has_characteristic PATO:0002418 ! acidophilic
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2009-12-22T04:23:25Z

[Term]
id: CL:0017503
name: basophilic cytoplasm
def: "Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions." [GOC:tfm]
is_a: GO:0005737 ! cytoplasm
intersection_of: GO:0005737 ! cytoplasm
intersection_of: has_characteristic PATO:0002094 ! basophilic
relationship: has_characteristic PATO:0002094 ! basophilic
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2009-12-22T04:24:54Z

[Term]
id: CL:0017504
name: polychromatophilic cytoplasm
def: "Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions." [GOC:tfm]
is_a: GO:0005737 ! cytoplasm
intersection_of: GO:0005737 ! cytoplasm
intersection_of: has_characteristic PATO:0070047 ! polychromatophilic
relationship: has_characteristic PATO:0070047 ! polychromatophilic
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228
creation_date: 2009-12-28T04:25:23Z

[Term]
id: CL:0019018
name: blood vessel smooth muscle cell
def: "A smooth muscle cell that is part of any blood vessel." [PMID:9108778]
subset: human_reference_atlas
synonym: "smooth muscle cell of blood vessel" EXACT []
is_a: CL:0000359 ! vascular associated smooth muscle cell
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0001981 ! blood vessel
relationship: part_of UBERON:0001981 ! blood vessel
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-2034-601X
property_value: http://purl.org/dc/terms/date "2020-07-21T12:42:48Z" xsd:dateTime
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:0019020
name: extrahepatic cholangiocyte
def: "An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes." [PMID:23720296]
synonym: "large bile duct cholangiocyte" EXACT [PMID:23720296]
is_a: CL:1000488 ! cholangiocyte
intersection_of: CL:1000488 ! cholangiocyte
intersection_of: part_of UBERON:0004822 ! extrahepatic bile duct epithelium
relationship: part_of UBERON:0004822 ! extrahepatic bile duct epithelium
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-2034-601X
property_value: http://purl.org/dc/terms/date "2020-09-03T12:24:24Z" xsd:dateTime

[Term]
id: CL:0019021
name: endothelial cell of periportal hepatic sinusoid
def: "An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid." [PMID:27423426]
subset: cellxgene_subset
synonym: "periportal hepatic sinusoidal endothelial cell" EXACT [PMID:30348985]
synonym: "periportal LSEC" EXACT [PMID:28287163]
xref: EFO:0010705
is_a: CL:1000398 ! endothelial cell of hepatic sinusoid
intersection_of: CL:1000398 ! endothelial cell of hepatic sinusoid
intersection_of: adjacent_to UBERON:0001279 ! portal triad
relationship: adjacent_to UBERON:0001279 ! portal triad
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-2034-601X
property_value: http://purl.org/dc/terms/date "2020-09-09T13:56:47Z" xsd:dateTime

[Term]
id: CL:0019022
name: endothelial cell of pericentral hepatic sinusoid
def: "An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid." [PMID:27423426]
subset: cellxgene_subset
synonym: "central venous hepatic sinusoidal endothelial cell" EXACT [PMID:30348985]
synonym: "pericentral LSEC" EXACT [PMID:28287163]
xref: EFO:0010706
is_a: CL:1000398 ! endothelial cell of hepatic sinusoid
intersection_of: CL:1000398 ! endothelial cell of hepatic sinusoid
intersection_of: adjacent_to UBERON:0006841 ! central vein of liver
relationship: adjacent_to UBERON:0006841 ! central vein of liver
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-2034-601X
property_value: http://purl.org/dc/terms/date "2020-09-10T12:38:29Z" xsd:dateTime

[Term]
id: CL:1000090
name: pronephric nephron tubule epithelial cell
is_a: CL:1000449 ! epithelial cell of nephron
is_a: CL:1000507 ! kidney tubule cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0005310 ! pronephric nephron tubule
relationship: part_of UBERON:0005310 ! pronephric nephron tubule

[Term]
id: CL:1000123
name: metanephric nephron tubule epithelial cell
is_a: CL:1000449 ! epithelial cell of nephron
is_a: CL:1000507 ! kidney tubule cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0005146 ! metanephric nephron tubule
relationship: part_of UBERON:0005146 ! metanephric nephron tubule

[Term]
id: CL:1000222
name: stomach neuroendocrine cell
is_a: CL:0000164 ! enteroendocrine cell
is_a: CL:0000165 ! neuroendocrine cell
is_a: CL:0002659 ! glandular cell of stomach
intersection_of: CL:0000165 ! neuroendocrine cell
intersection_of: part_of UBERON:0000945 ! stomach
relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata)

[Term]
id: CL:1000223
name: lung neuroendocrine cell
def: "A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Lung neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Lung neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury." [doi:10.3109/01902148209069653, doi:10.7554/eLife.78216, PMID:33355253]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "PNEC" RELATED OMO:0003000 [PMID:33355253]
synonym: "pulmonary neuroendocrine cell" EXACT [PMID:33355253]
is_a: CL:0000006 ! neuronal receptor cell
is_a: CL:0000082 ! epithelial cell of lung
is_a: CL:0000098 ! sensory epithelial cell
is_a: CL:0000165 ! neuroendocrine cell
is_a: CL:0000206 ! chemoreceptor cell
is_a: CL:0000458 ! serotonin secreting cell
is_a: CL:1000272 ! lung secretory cell
intersection_of: CL:0000165 ! neuroendocrine cell
intersection_of: part_of UBERON:0002048 ! lung
relationship: capable_of GO:0070483 ! detection of hypoxia
relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: has_part GO:0031045 ! dense core granule
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000271
name: lung ciliated cell
subset: cellxgene_subset
subset: human_reference_atlas
is_a: CL:4030034 ! respiratory ciliated cell
intersection_of: CL:0000064 ! ciliated cell
intersection_of: part_of UBERON:0002048 ! lung
relationship: part_of UBERON:0002048 ! lung
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000272
name: lung secretory cell
subset: cellxgene_subset
is_a: CL:0000151 ! secretory cell
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000151 ! secretory cell
intersection_of: part_of UBERON:0002048 ! lung
relationship: part_of UBERON:0002048 ! lung

[Term]
id: CL:1000274
name: trophectodermal cell
synonym: "trophectoderm cell" EXACT []
is_a: CL:0000349 ! extraembryonic cell

[Term]
id: CL:1000275
name: smooth muscle cell of small intestine
def: "A smooth muscle cell that is part of the small intestine." [GOC:tfm]
subset: cellxgene_subset
synonym: "non-striated muscle fiber of small intestine" EXACT [FMA:15050]
xref: FMA:15050
is_a: CL:0002504 {is_inferred="true"} ! enteric smooth muscle cell
intersection_of: CL:0002504 ! enteric smooth muscle cell
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0002108 ! small intestine

[Term]
id: CL:1000276
name: smooth muscle fiber of duodenum
def: "A smooth muscle cell that is part of the duodenum." [GOC:tfm]
synonym: "non-striated muscle fiber of duodenum" EXACT [FMA:15058]
xref: FMA:15058
is_a: CL:1000275 {is_inferred="true"} ! smooth muscle cell of small intestine
intersection_of: CL:1000275 ! smooth muscle cell of small intestine
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: part_of UBERON:0002114 ! duodenum

[Term]
id: CL:1000279
name: smooth muscle cell of large intestine
def: "A smooth muscle cell that is part of the large intestine." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "non-striated muscle fiber of large intestine" EXACT [FMA:15653]
xref: FMA:15653
is_a: CL:0002504 {is_inferred="true"} ! enteric smooth muscle cell
intersection_of: CL:0002504 ! enteric smooth muscle cell
intersection_of: part_of UBERON:0000059 ! large intestine
relationship: part_of UBERON:0000059 ! large intestine
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000280
name: smooth muscle cell of colon
def: "A smooth muscle cell that is part of the colon." [GOC:tfm]
synonym: "non-striated muscle fiber of colon" EXACT [FMA:15663]
xref: FMA:15663
is_a: CL:1000279 ! smooth muscle cell of large intestine
intersection_of: CL:0002504 ! enteric smooth muscle cell
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon

[Term]
id: CL:1000285
name: smooth muscle cell of sigmoid colon
def: "A smooth muscle cell that is part of the sigmoid colon." [GOC:tfm]
synonym: "non-striated muscle fiber of sigmoid colon" EXACT [FMA:17521]
xref: FMA:17521
is_a: CL:1000280 {is_inferred="true"} ! smooth muscle cell of colon
intersection_of: CL:1000280 ! smooth muscle cell of colon
intersection_of: part_of UBERON:0001159 ! sigmoid colon
relationship: part_of UBERON:0001159 ! sigmoid colon

[Term]
id: CL:1000286
name: smooth muscle cell of rectum
def: "A smooth muscle cell that is part of the rectum." [GOC:tfm]
synonym: "non-striated muscle fiber of rectum" EXACT [FMA:17522]
synonym: "smooth muscle fiber of rectum" EXACT []
xref: FMA:17522
is_a: CL:1000279 ! smooth muscle cell of large intestine
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0001052 ! rectum
relationship: part_of UBERON:0001052 ! rectum

[Term]
id: CL:1000296
name: epithelial cell of urethra
def: "An epithelial cell that is part of the urethra." [GOC:tfm]
subset: cellxgene_subset
xref: FMA:256165
is_a: CL:0000066 ! epithelial cell
is_a: CL:1001320 ! urethra cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0000057 ! urethra

[Term]
id: CL:1000303
name: fibroblast of areolar connective tissue
def: "A fibroblast that is part of the areolar connective tissue." [GOC:tfm]
xref: FMA:261279
is_a: CL:0000057 {is_inferred="true"} ! fibroblast
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0006815 ! areolar connective tissue
relationship: part_of UBERON:0006815 ! areolar connective tissue

[Term]
id: CL:1000306
name: fibroblast of tunica adventitia of artery
def: "A fibroblast that is part of the tunica adventitia of artery." [GOC:tfm]
xref: FMA:261285
is_a: CL:0000057 {is_inferred="true"} ! fibroblast
is_a: CL:0002503 ! adventitial cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0005734 ! tunica adventitia of blood vessel
relationship: part_of UBERON:0005734 ! tunica adventitia of blood vessel

[Term]
id: CL:1000307
name: fibroblast of dense regular elastic tissue
def: "A fibroblast that is part of the dense regular elastic tissue." [GOC:tfm]
xref: FMA:261287
is_a: CL:0000057 ! fibroblast
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0007846 ! dense regular connective tissue
relationship: part_of UBERON:0002521 ! elastic tissue
relationship: part_of UBERON:0007846 ! dense regular connective tissue

[Term]
id: CL:1000309
name: epicardial adipocyte
def: "An adipocyte that is part of the epicardial fat." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "adipocyte of epicardial fat" EXACT [FMA:261293]
synonym: "epicardial fat cell" EXACT [FMA:261293]
xref: FMA:261293
is_a: CL:0000136 ! adipocyte
is_a: CL:0002494 ! cardiocyte
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: part_of UBERON:0002348 ! epicardium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000310
name: adipocyte of epicardial fat of right ventricle
def: "An adipocyte that is part of the epicardial fat of right ventricle." [GOC:tfm]
synonym: "epicardial adipocyte of right ventricle" EXACT [FMA:261297]
synonym: "epicardial fat cell of right ventricle" EXACT [FMA:261297]
xref: FMA:261297
is_a: CL:1000309 ! epicardial adipocyte
intersection_of: CL:1000309 ! epicardial adipocyte
intersection_of: part_of UBERON:0002080 ! heart right ventricle
relationship: part_of UBERON:0002080 ! heart right ventricle

[Term]
id: CL:1000311
name: adipocyte of epicardial fat of left ventricle
def: "An adipocyte that is part of the epicardial fat of left ventricle." [GOC:tfm]
subset: cellxgene_subset
synonym: "epicardial adipocyte of left ventricle" EXACT [FMA:261300]
synonym: "epicardial fat cell of left ventricle" EXACT [FMA:261300]
xref: FMA:261300
is_a: CL:1000309 ! epicardial adipocyte
intersection_of: CL:1000309 ! epicardial adipocyte
intersection_of: part_of UBERON:0002084 ! heart left ventricle
relationship: part_of UBERON:0002084 ! heart left ventricle

[Term]
id: CL:1000361
name: transitional myocyte of interatrial septum
def: "A transitional myocyte that is part of the interatrial septum." [GOC:tfm]
xref: FMA:263152
is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte
is_a: CL:2000022 ! cardiac septum cell
intersection_of: CL:0002073 ! transitional myocyte
intersection_of: part_of UBERON:0002085 ! interatrial septum
relationship: part_of UBERON:0002085 ! interatrial septum

[Term]
id: CL:1000362
name: transitional myocyte of interventricular septum
def: "A transitional myocyte that is part of the interventricular septum." [GOC:tfm]
xref: FMA:263154
is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte
is_a: CL:2000022 ! cardiac septum cell
intersection_of: CL:0002073 ! transitional myocyte
intersection_of: part_of UBERON:0002094 ! interventricular septum
relationship: part_of UBERON:0002094 ! interventricular septum

[Term]
id: CL:1000376
name: Purkinje myocyte of interventricular septum
def: "A Purkinje myocyte that is part of the interventricular septum." [GOC:tfm]
xref: FMA:263182
is_a: CL:0002068 {is_inferred="true"} ! Purkinje myocyte
is_a: CL:2000022 ! cardiac septum cell
intersection_of: CL:0002068 ! Purkinje myocyte
intersection_of: part_of UBERON:0002094 ! interventricular septum
relationship: part_of UBERON:0002094 ! interventricular septum

[Term]
id: CL:1000398
name: endothelial cell of hepatic sinusoid
def: "An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates." [GOC:tfm, PMID:3926620]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "endotheliocyte of hepatic sinusoid" EXACT [FMA:62911]
synonym: "liver sinusoidal endothelial cell" EXACT [PMID:30348985]
synonym: "LSEC" EXACT [PMID:30348985]
xref: BTO:000125
xref: FMA:62911
is_a: CL:0002262 ! endothelial cell of sinusoid
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0001281 ! hepatic sinusoid
relationship: part_of UBERON:0001281 ! hepatic sinusoid
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000409
name: myocyte of sinoatrial node
def: "A muscle cell that is part of the sinoatrial node." [FMA:67102, GOC:tfm]
synonym: "SA nodal myocyte" EXACT [FMA:67102]
synonym: "SA node cardiac muscle cell" EXACT [GOC:pr]
synonym: "sinoatrial node cell" EXACT [GOC:pr]
synonym: "sinoatrial node myocyte" EXACT []
synonym: "sinuatrial node myocyte" EXACT [FMA:67102]
xref: FMA:67102
is_a: CL:0002072 ! nodal myocyte
is_a: CL:0008009 ! transversely striated visceral muscle cell
intersection_of: CL:0000187 ! muscle cell
intersection_of: part_of UBERON:0002351 ! sinoatrial node
relationship: part_of UBERON:0002351 ! sinoatrial node

[Term]
id: CL:1000410
name: myocyte of atrioventricular node
def: "A muscle cell that is part of the atrioventricular node." [FMA:67106, GOC:tfm]
synonym: "atrioventricular node cell" EXACT [GOC:pr]
synonym: "atrioventricular node myocyte" EXACT [FMA:67106]
synonym: "AV nodal myocyte" EXACT [FMA:67106]
synonym: "AV node cardiac muscle cell" EXACT [GOC:pr]
synonym: "AV node cell" EXACT [GOC:pr]
xref: FMA:67106
is_a: CL:0002072 ! nodal myocyte
is_a: CL:0008009 ! transversely striated visceral muscle cell
is_a: CL:2000022 ! cardiac septum cell
intersection_of: CL:0000187 ! muscle cell
intersection_of: part_of UBERON:0002352 ! atrioventricular node
relationship: part_of UBERON:0002352 ! atrioventricular node

[Term]
id: CL:1000412
name: endothelial cell of arteriole
def: "An endothelial cell that is part of the arteriole." [GOC:tfm]
subset: human_reference_atlas
xref: FMA:67760
xref: KUPO:0001097
is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0001980 ! arteriole
relationship: part_of UBERON:0001980 ! arteriole
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000413
name: endothelial cell of artery
def: "A blood vessel endothelial cell that is part of an arterial endothelium." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "arterial endothelial cell" EXACT []
xref: BTO:0004758
xref: FMA:67761
xref: KUPO:0001095
is_a: CL:0000071 ! blood vessel endothelial cell
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0001637 ! artery
relationship: part_of UBERON:0001917 ! endothelium of artery
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000414
name: endothelial cell of venule
def: "An endothelial cell that is part of the venule." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
xref: FMA:67762
is_a: CL:0002139 {is_inferred="true"} ! endothelial cell of vascular tree
intersection_of: CL:0002139 ! endothelial cell of vascular tree
intersection_of: part_of UBERON:0001979 ! venule
relationship: part_of UBERON:0001979 ! venule
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000415
name: epithelial cell of gallbladder
def: "An epithelial cell that is part of the gallbladder." [GOC:tfm]
xref: FMA:67780
is_a: CL:0000066 ! epithelial cell
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0002110 ! gallbladder
relationship: part_of UBERON:0002110 ! gallbladder

[Term]
id: CL:1000428
name: stem cell of epidermis
def: "A somatic stem cell that is part of the epidermis." [GOC:tfm]
subset: cellxgene_subset
synonym: "epidermal stem cell" EXACT [FMA:70541]
xref: FMA:70541
is_a: CL:0000723 {is_inferred="true"} ! somatic stem cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000723 ! somatic stem cell
intersection_of: part_of UBERON:0001003 ! skin epidermis
relationship: part_of UBERON:0001003 ! skin epidermis

[Term]
id: CL:1000443
name: ciliary muscle cell
def: "A smooth muscle cell that is part of the ciliary body." [GOC:tfm]
subset: cellxgene_subset
subset: eye_upper_slim
synonym: "smooth muscle cell of ciliary body" EXACT [FMA:70610]
xref: FMA:70610
is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0001775 ! ciliary body
relationship: part_of UBERON:0001775 ! ciliary body

[Term]
id: CL:1000444
name: mesothelial cell of anterior chamber of eye
def: "A mesothelial cell that is part of the anterior chamber of eyeball." [GOC:tfm]
xref: FMA:70615
is_a: CL:0000077 ! mesothelial cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000077 ! mesothelial cell
intersection_of: part_of UBERON:0001766 ! anterior chamber of eyeball
relationship: part_of UBERON:0001766 ! anterior chamber of eyeball

[Term]
id: CL:1000449
name: epithelial cell of nephron
def: "An epithelial cell that is part of the nephron." [GOC:tfm]
subset: cellxgene_subset
xref: FMA:70965
is_a: CL:0002518 ! kidney epithelial cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0001285 ! nephron
relationship: part_of UBERON:0001285 ! nephron

[Term]
id: CL:1000454
name: kidney collecting duct epithelial cell
def: "An epithelial cell that is part of the collecting duct of renal tubule." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
subset: kidney_upper_slim
synonym: "epithelial cell of renal collecting tubule" EXACT [FMA:70982]
xref: FMA:70982
xref: KUPO:0001059
is_a: CL:0000072 {is_inferred="true"} ! non-branched duct epithelial cell
is_a: CL:1000449 ! epithelial cell of nephron
is_a: CL:1001225 {is_inferred="true"} ! kidney collecting duct cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000456
name: mesothelial cell of parietal peritoneum
def: "A mesothelial cell that is part of the parietal peritoneum." [GOC:tfm]
xref: FMA:72142
is_a: CL:1000490 ! mesothelial cell of peritoneum
intersection_of: CL:0000077 ! mesothelial cell
intersection_of: part_of UBERON:0001366 ! parietal peritoneum
relationship: part_of UBERON:0001366 ! parietal peritoneum

[Term]
id: CL:1000457
name: mesothelial cell of visceral peritoneum
def: "A mesothelial cell that is part of the visceral peritoneum." [GOC:tfm]
subset: human_reference_atlas
xref: FMA:72143
is_a: CL:1000490 ! mesothelial cell of peritoneum
intersection_of: CL:0000077 ! mesothelial cell
intersection_of: part_of UBERON:0001178 ! visceral peritoneum
relationship: part_of UBERON:0001178 ! visceral peritoneum
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000478
name: transitional myocyte of sinoatrial node
def: "A transitional myocyte that is part of the sinoatrial node." [GOC:tfm]
synonym: "transitinal myocyte of sinuatrial node" EXACT []
xref: FMA:83384
is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte
is_a: CL:1000409 ! myocyte of sinoatrial node
intersection_of: CL:0002073 ! transitional myocyte
intersection_of: part_of UBERON:0002351 ! sinoatrial node

[Term]
id: CL:1000479
name: Purkinje myocyte of atrioventricular node
def: "A Purkinje myocyte that is part of the atrioventricular node." [GOC:tfm]
xref: FMA:83386
is_a: CL:0002068 {is_inferred="true"} ! Purkinje myocyte
is_a: CL:1000410 ! myocyte of atrioventricular node
intersection_of: CL:0002068 ! Purkinje myocyte
intersection_of: part_of UBERON:0002352 ! atrioventricular node

[Term]
id: CL:1000482
name: myocardial endocrine cell of interventricular septum
def: "A myocardial endocrine cell that is part of the interventricular septum." [GOC:tfm]
xref: FMA:83390
is_a: CL:0002074 {is_inferred="true"} ! myocardial endocrine cell
is_a: CL:2000022 ! cardiac septum cell
intersection_of: CL:0002074 ! myocardial endocrine cell
intersection_of: part_of UBERON:0002094 ! interventricular septum
relationship: part_of UBERON:0002094 ! interventricular septum

[Term]
id: CL:1000488
name: cholangiocyte
def: "An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts." [GOC:tfm, PMID:16550043, PMID:18356246]
subset: cellxgene_subset
synonym: "epithelial cell of bile duct" EXACT []
xref: FMA:86481
is_a: CL:0000069 {is_inferred="true"} ! branched duct epithelial cell
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000069 ! branched duct epithelial cell
intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity
intersection_of: part_of UBERON:0002394 ! bile duct
relationship: develops_from CL:0005026 ! hepatoblast
relationship: part_of UBERON:0002394 ! bile duct

[Term]
id: CL:1000490
name: mesothelial cell of peritoneum
def: "A mesothelial cell that is part of the peritoneum." [GOC:tfm]
synonym: "peritoneal mesothelial cell" EXACT [FMA:86736]
xref: FMA:86736
is_a: CL:0000077 ! mesothelial cell
intersection_of: CL:0000077 ! mesothelial cell
intersection_of: part_of UBERON:0002358 ! peritoneum
relationship: part_of UBERON:0002358 ! peritoneum

[Term]
id: CL:1000491
name: mesothelial cell of pleura
def: "A mesothelial cell that is part of the pleura." [GOC:tfm]
subset: cellxgene_subset
synonym: "pleural mesothelial cell" EXACT [FMA:86737]
xref: FMA:86737
is_a: CL:0000077 ! mesothelial cell
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: CL:0000077 ! mesothelial cell
intersection_of: part_of UBERON:0000977 ! pleura
relationship: part_of UBERON:0000977 ! pleura

[Term]
id: CL:1000492
name: mesothelial cell of parietal pleura
def: "A mesothelial cell that is part of the parietal pleura." [GOC:tfm]
xref: FMA:86738
is_a: CL:1000491 ! mesothelial cell of pleura
intersection_of: CL:0000077 ! mesothelial cell
intersection_of: part_of UBERON:0002400 ! parietal pleura
relationship: part_of UBERON:0002400 ! parietal pleura

[Term]
id: CL:1000493
name: mesothelial cell of visceral pleura
def: "A mesothelial cell that is part of the visceral pleura." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
xref: FMA:86739
is_a: CL:0000082 ! epithelial cell of lung
is_a: CL:1000491 ! mesothelial cell of pleura
intersection_of: CL:0000077 ! mesothelial cell
intersection_of: part_of UBERON:0002401 ! visceral pleura
relationship: part_of UBERON:0002401 ! visceral pleura
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000494
name: nephron tubule epithelial cell
def: "An epithelial cell that is part of a nephron tubule." [GOC:tfm]
comment: This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON.
subset: cellxgene_subset
synonym: "kidney tubule epithelial cell" EXACT []
xref: FMA:86785
xref: KUPO:0001022
is_a: CL:1000449 ! epithelial cell of nephron
is_a: CL:1000507 ! kidney tubule cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0004810 ! nephron tubule epithelium
relationship: part_of UBERON:0004810 ! nephron tubule epithelium

[Term]
id: CL:1000497
name: kidney cell
def: "A cell that is part of a kidney." []
subset: cellxgene_subset
xref: KUPO:0001010
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0002113 ! kidney

[Term]
id: CL:1000500
name: kidney interstitial cell
def: "A cell that is part of kidney interstitium." []
subset: cellxgene_subset
subset: kidney_upper_slim
xref: KUPO:0001013
is_a: CL:1000497 ! kidney cell
is_a: CL:4030031 ! interstitial cell
intersection_of: CL:1000497 ! kidney cell
intersection_of: part_of UBERON:0005215 ! kidney interstitium
relationship: part_of UBERON:0005215 ! kidney interstitium

[Term]
id: CL:1000505
name: kidney pelvis cell
def: "A cell that is part of a renal pelvis." []
subset: kidney_upper_slim
xref: KUPO:0001018
is_a: CL:1000497 ! kidney cell
intersection_of: CL:1000497 ! kidney cell
intersection_of: part_of UBERON:0001224 ! renal pelvis
relationship: part_of UBERON:0001224 ! renal pelvis

[Term]
id: CL:1000507
name: kidney tubule cell
def: "A cell that is part of a nephron tubule." []
subset: kidney_upper_slim
xref: KUPO:0001020
is_a: CL:1000497 ! kidney cell
intersection_of: CL:1000497 ! kidney cell
intersection_of: part_of UBERON:0001231 ! nephron tubule
relationship: part_of UBERON:0001231 ! nephron tubule

[Term]
id: CL:1000549
name: kidney cortex collecting duct epithelial cell
def: "An epithelial cell that is part of a cortical collecting duct." []
xref: KUPO:0001063
is_a: CL:0002584 ! renal cortical epithelial cell
is_a: CL:1000454 ! kidney collecting duct epithelial cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0004203 ! cortical collecting duct
relationship: part_of UBERON:0004203 ! cortical collecting duct

[Term]
id: CL:1000600
name: lower urinary tract cell
xref: KUPO:0001115
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0001556 ! lower urinary tract
relationship: part_of UBERON:0001556 ! lower urinary tract

[Term]
id: CL:1000601
name: ureteral cell
xref: KUPO:0001116
is_a: CL:0000000 ! cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0000056 ! ureter
relationship: part_of UBERON:0000056 ! ureter

[Term]
id: CL:1000606
name: kidney nerve cell
xref: KUPO:0001015
is_a: CL:1000500 ! kidney interstitial cell
is_a: CL:2000032 ! peripheral nervous system neuron
intersection_of: CL:0000540 ! neuron
intersection_of: has_soma_location UBERON:0002113 ! kidney
relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: has_soma_location UBERON:0002113 ! kidney

[Term]
id: CL:1000681
name: kidney cortex interstitial cell
xref: KUPO:0001091
is_a: CL:0002584 ! renal cortical epithelial cell
is_a: CL:1000500 {is_inferred="true"} ! kidney interstitial cell
intersection_of: CL:1000500 ! kidney interstitial cell
intersection_of: part_of UBERON:0005270 ! renal cortex interstitium
relationship: part_of UBERON:0005270 ! renal cortex interstitium

[Term]
id: CL:1000692
name: kidney interstitial fibroblast
subset: cellxgene_subset
subset: human_reference_atlas
xref: KUPO:0001102
is_a: CL:0000057 ! fibroblast
is_a: CL:1000500 ! kidney interstitial cell
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0005215 ! kidney interstitium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000702
name: kidney pelvis smooth muscle cell
xref: KUPO:0001113
is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell
is_a: CL:1000505 {is_inferred="true"} ! kidney pelvis cell
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0004227 ! kidney pelvis smooth muscle
relationship: part_of UBERON:0004227 ! kidney pelvis smooth muscle

[Term]
id: CL:1000708
name: ureter adventitial cell
subset: human_reference_atlas
xref: KUPO:0001119
is_a: CL:0000115 ! endothelial cell
is_a: CL:0002503 ! adventitial cell
is_a: CL:1000601 {is_inferred="true"} ! ureteral cell
intersection_of: CL:1000601 ! ureteral cell
intersection_of: part_of UBERON:0001252 ! adventitia of ureter
relationship: part_of UBERON:0001252 ! adventitia of ureter
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000714
name: kidney cortex collecting duct principal cell
subset: human_reference_atlas
xref: KUPO:0001130
is_a: CL:1000549 {is_inferred="true"} ! kidney cortex collecting duct epithelial cell
is_a: CL:1001431 ! kidney collecting duct principal cell
intersection_of: CL:0005009 ! renal principal cell
intersection_of: part_of UBERON:0004203 ! cortical collecting duct
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1000979
name: ureter smooth muscle cell
xref: KUPO:0001118
is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell
is_a: CL:1000601 {is_inferred="true"} ! ureteral cell
intersection_of: CL:0000192 ! smooth muscle cell
intersection_of: part_of UBERON:0006855 ! muscular coat of ureter
relationship: part_of UBERON:0006855 ! muscular coat of ureter

[Term]
id: CL:1001225
name: kidney collecting duct cell
def: "A cell that is part of a collecting duct of renal tubule." []
subset: cellxgene_subset
xref: KUPO:0001012
xref: Wikipedia:Kidney_collecting_duct_cell
is_a: CL:1000497 ! kidney cell
intersection_of: CL:1000497 ! kidney cell
intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule
relationship: part_of UBERON:0001232 ! collecting duct of renal tubule

[Term]
id: CL:1001319
name: bladder cell
subset: cellxgene_subset
subset: human_reference_atlas
xref: KUPO:0001120
is_a: CL:1000600 ! lower urinary tract cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0001255 ! urinary bladder
relationship: part_of UBERON:0001255 ! urinary bladder
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1001320
name: urethra cell
xref: KUPO:0001123
is_a: CL:1000600 ! lower urinary tract cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0000057 ! urethra
relationship: part_of UBERON:0000057 ! urethra

[Term]
id: CL:1001431
name: kidney collecting duct principal cell
subset: cellxgene_subset
subset: human_reference_atlas
xref: KUPO:0001128
is_a: CL:0005009 {is_inferred="true"} ! renal principal cell
is_a: CL:1000454 ! kidney collecting duct epithelial cell
intersection_of: CL:0005009 ! renal principal cell
intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1001433
name: epithelial cell of exocrine pancreas
def: "An epithelial cell of the exocrine pancreas." [GOC:tfm]
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "exocrine pancreas cell" EXACT []
xref: FMA:70986
is_a: CL:0000083 ! epithelial cell of pancreas
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0000017 ! exocrine pancreas
relationship: part_of UBERON:0000017 ! exocrine pancreas
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1001516
name: intestinal enteroendocrine cell
def: "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract." [MP:0010802]
subset: cellxgene_subset
is_a: CL:0000164 ! enteroendocrine cell
is_a: CL:0002563 ! intestinal epithelial cell
intersection_of: CL:0000164 ! enteroendocrine cell
intersection_of: part_of UBERON:0001242 ! intestinal mucosa

[Term]
id: CL:1001567
name: lung endothelial cell
synonym: "endothelial cell of lung" RELATED []
synonym: "pulmonary vessel endothelial cell" RELATED []
is_a: CL:0000082 ! epithelial cell of lung
is_a: CL:0002139 ! endothelial cell of vascular tree
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: CL:0002139 ! endothelial cell of vascular tree
intersection_of: part_of UBERON:0002048 ! lung
relationship: part_of UBERON:0000102 ! lung vasculature

[Term]
id: CL:1001568
name: pulmonary artery endothelial cell
subset: cellxgene_subset
subset: human_reference_atlas
synonym: "PAEC cell" RELATED [BTO:0001141]
xref: BTO:0001141
is_a: CL:1000413 ! endothelial cell of artery
intersection_of: CL:0002139 ! endothelial cell of vascular tree
intersection_of: part_of UBERON:0002012 ! pulmonary artery
relationship: part_of UBERON:0005317 ! pulmonary artery endothelium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1001572
name: colon endothelial cell
def: "A vascular endothelial cell found in colon blood vessels." [https://orcid.org/0000-0001-5208-3432, NPX:PDR]
synonym: "colon endothelial cells" RELATED OMO:0003004 [CALOHA:TS-2397]
synonym: "colonic endothelial cell" RELATED [CALOHA:TS-2397]
xref: CALOHA:TS-2397
is_a: CL:0000115 ! endothelial cell
is_a: CL:0011108 ! colon epithelial cell
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0013695 ! colon endothelium

[Term]
id: CL:1001576
name: oral mucosa squamous cell
def: "Squamous cell of oral epithelium." [NPX:PDR]
synonym: "oral cavity mucosa squamous cell" RELATED [CALOHA:TS-1252]
synonym: "oral cavity mucosa squamous epithelial cell" RELATED [CALOHA:TS-1252]
synonym: "oral mucosa squamous epithelial cell" RELATED [CALOHA:TS-1252]
synonym: "oral mucosa squamous epithelial cells" RELATED [CALOHA:TS-1252]
xref: CALOHA:TS-1252
is_a: CL:0000076 ! squamous epithelial cell
is_a: CL:0002251 ! epithelial cell of alimentary canal
intersection_of: CL:0000076 ! squamous epithelial cell
intersection_of: part_of UBERON:0002424 ! oral epithelium
relationship: part_of UBERON:0002424 ! oral epithelium

[Term]
id: CL:1001588
name: colon glandular cell
def: "Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells." [NPX:PDR]
synonym: "colon glandular cells" RELATED [CALOHA:TS-1274]
xref: CALOHA:TS-1274
is_a: CL:0002658 ! glandular cell of the large intestine
is_a: CL:0011108 ! colon epithelial cell
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0001155 ! colon

[Term]
id: CL:1001589
name: duodenum glandular cell
def: "Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell." [NPX:PDR]
subset: cellxgene_subset
synonym: "duodenum glandular cells" RELATED [CALOHA:TS-1275]
xref: CALOHA:TS-1275
is_a: CL:1001598 ! small intestine glandular cell
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: part_of UBERON:0008346 ! duodenal epithelium

[Term]
id: CL:1001590
name: epididymis glandular cell
def: "Glandular cell of epididymal epithelium." [NPX:PDR]
synonym: "epididymal glandular cell" RELATED [CALOHA:TS-1276]
synonym: "epididymis glandular cells" RELATED [CALOHA:TS-1276]
xref: CALOHA:TS-1276
is_a: CL:0000068 ! duct epithelial cell
is_a: CL:0000150 ! glandular epithelial cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0001301 ! epididymis
relationship: part_of UBERON:0004544 ! epididymis epithelium

[Term]
id: CL:1001591
name: oviduct glandular cell
def: "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells." [HPA:HPA, NPX:PDR]
synonym: "fallopian tube glandular cell" RELATED [CALOHA:TS-1277]
synonym: "fallopian tube glandular cells" RELATED [CALOHA:TS-1277]
synonym: "uterine tube glandular cell" RELATED [CALOHA:TS-1277]
xref: CALOHA:TS-1277
is_a: CL:0000150 ! glandular epithelial cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0000993 ! oviduct
relationship: part_of UBERON:0004804 ! oviduct epithelium

[Term]
id: CL:1001592
name: gallbladder glandular cell
def: "Glandular cell of gallbladder epithelium." [NPX:PDR]
synonym: "gall bladder glandular cell" EXACT [FMA:7202]
synonym: "gall bladder glandular cells" RELATED [CALOHA:TS-1278]
synonym: "gallbladder glandular cells" RELATED [CALOHA:TS-1278]
xref: CALOHA:TS-1278
is_a: CL:0000150 ! glandular epithelial cell
is_a: CL:1000415 ! epithelial cell of gallbladder
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0002110 ! gallbladder
relationship: part_of UBERON:0002029 ! epithelium of gall bladder

[Term]
id: CL:1001595
name: rectum glandular cell
def: "Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells." [NPX:PDR]
synonym: "rectal glandular cell" RELATED [CALOHA:TS-1281]
synonym: "rectum glandular cells" RELATED [CALOHA:TS-1281]
xref: CALOHA:TS-1281
is_a: CL:0002658 ! glandular cell of the large intestine
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0001052 ! rectum
relationship: part_of UBERON:0003354 ! epithelium of rectum

[Term]
id: CL:1001597
name: seminal vesicle glandular cell
def: "Glandular cell of seminal vesicle epithelium." [NPX:PDR]
subset: cellxgene_subset
synonym: "seminal vesicle glandular cells" RELATED [CALOHA:TS-1283]
xref: CALOHA:TS-1283
is_a: CL:0000068 ! duct epithelial cell
is_a: CL:0000150 ! glandular epithelial cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0000998 ! seminal vesicle
relationship: part_of UBERON:0004805 ! seminal vesicle epithelium

[Term]
id: CL:1001598
name: small intestine glandular cell
def: "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) ." [NCI_Thesaurus:Small_Intestinal_Glandular_Cell, NPX:PDR]
synonym: "small bowel glandular cell" RELATED [CALOHA:TS-1286]
synonym: "small intestinal glandular cell" RELATED [CALOHA:TS-1286]
synonym: "small intestine glandular cells" RELATED [CALOHA:TS-1286]
xref: CALOHA:TS-1286
xref: FMA:86928
is_a: CL:0000150 ! glandular epithelial cell
is_a: CL:0002254 ! epithelial cell of small intestine
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0001902 ! epithelium of small intestine

[Term]
id: CL:1001599
name: pancreas exocrine glandular cell
def: "Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts." [HPA:HPA, NPX:PDR]
subset: human_reference_atlas
synonym: "exocrine pancreas glandular cell" RELATED [CALOHA:TS-1242]
synonym: "pancreas exocrine glandular cells" RELATED [CALOHA:TS-1242]
xref: BTO:0000028
xref: CALOHA:TS-1242
is_a: CL:0000150 ! glandular epithelial cell
is_a: CL:0000152 ! exocrine cell
is_a: CL:1001433 ! epithelial cell of exocrine pancreas
intersection_of: CL:0000150 ! glandular epithelial cell
intersection_of: part_of UBERON:0000017 ! exocrine pancreas
relationship: part_of UBERON:0013697 ! exocrine pancreas epithelium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:1001609
name: muscle fibroblast
def: "Fibroblast from muscle organ." [NPX:PDR]
xref: CALOHA:TS-0643
is_a: CL:0000057 ! fibroblast
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0001630 ! muscle organ
relationship: part_of UBERON:0001630 ! muscle organ

[Term]
id: CL:1001610
name: bone marrow hematopoietic cell
def: "Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes." [NPX:PDR]
synonym: "bone marrow hematopoietic cells" RELATED [CALOHA:TS-2109]
synonym: "bone marrow poietic cells" RELATED [CALOHA:TS-2109]
xref: CALOHA:TS-2109
is_a: CL:0000988 ! hematopoietic cell
is_a: CL:0002092 ! bone marrow cell
intersection_of: CL:0000988 ! hematopoietic cell
intersection_of: part_of UBERON:0002371 ! bone marrow
relationship: part_of UBERON:0012429 ! hematopoietic tissue

[Term]
id: CL:2000001
name: peripheral blood mononuclear cell
def: "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." [GOC:TermGenie]
subset: cellxgene_subset
is_a: CL:0000080 ! circulating cell
is_a: CL:0000842 ! mononuclear cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000842 ! mononuclear cell
intersection_of: part_of UBERON:0000178 ! blood
relationship: part_of UBERON:0000178 ! blood
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-02-11T17:29:04Z

[Term]
id: CL:2000002
name: decidual cell
def: "A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization." [BTO:0002770, NCIT:C32429, PMID:30013421, PMID:30429548, Wiki:Decidual_cells&oldid=937509751, Wiki:Decidualization&oldid=908981933]
subset: cellxgene_subset
synonym: "decidua cell" EXACT [BTO:0002770, NCIT:C32429]
synonym: "decidual stromal cell" EXACT [BTO:0005756, PMID:11719592]
xref: BTO:0002770
xref: BTO:0005756
xref: NCIT:C32429
is_a: CL:0000349 ! extraembryonic cell
is_a: CL:0000499 ! stromal cell
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: develops_from CL:0002255 ! stromal cell of endometrium
relationship: part_of UBERON:0002450 ! decidua
creation_date: 2014-02-20T23:06:41Z

[Term]
id: CL:2000008
name: microvascular endothelial cell
def: "Any blood vessel endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie]
is_a: CL:0000071 ! blood vessel endothelial cell
intersection_of: CL:0000071 ! blood vessel endothelial cell
intersection_of: part_of UBERON:0008339 ! microvascular endothelium
relationship: part_of UBERON:0008339 ! microvascular endothelium
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-06-04T15:07:42Z

[Term]
id: CL:2000010
name: dermis blood vessel endothelial cell
def: "Any blood vessel endothelial cell that is part of a dermis." [GOC:TermGenie]
is_a: CL:0000071 ! blood vessel endothelial cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000071 ! blood vessel endothelial cell
intersection_of: part_of UBERON:0002067 ! dermis
relationship: part_of UBERON:0002067 ! dermis
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-06-04T15:12:06Z

[Term]
id: CL:2000013
name: fibroblast of skin of abdomen
def: "Any skin fibroblast that is part of a skin of abdomen." [GOC:TermGenie]
is_a: CL:0002620 ! skin fibroblast
intersection_of: CL:0002620 ! skin fibroblast
intersection_of: part_of UBERON:0001416 ! skin of abdomen
relationship: part_of UBERON:0001416 ! skin of abdomen
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-06-04T15:18:16Z

[Term]
id: CL:2000016
name: lung microvascular endothelial cell
def: "Any lung endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie]
subset: cellxgene_subset
is_a: CL:1001567 ! lung endothelial cell
is_a: CL:2000008 ! microvascular endothelial cell
intersection_of: CL:1001567 ! lung endothelial cell
intersection_of: part_of UBERON:0008339 ! microvascular endothelium
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-06-04T16:00:56Z

[Term]
id: CL:2000019
name: compound eye photoreceptor cell
def: "Any photoreceptor cell that is part of a compound eye." [GOC:TermGenie]
xref: FBbt:00004211
is_a: CL:0000287 ! eye photoreceptor cell
intersection_of: CL:0000210 ! photoreceptor cell
intersection_of: part_of UBERON:0000018 ! compound eye
relationship: part_of UBERON:0000018 ! compound eye
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-06-24T23:16:45Z

[Term]
id: CL:2000020
name: inner cell mass cell
def: "Any native cell that is part of a inner cell mass." [GOC:TermGenie]
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0000087 ! inner cell mass
relationship: part_of UBERON:0000087 ! inner cell mass
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-06-24T23:16:53Z

[Term]
id: CL:2000022
name: cardiac septum cell
def: "Any native cell that is part of a cardiac septum." [GOC:TermGenie]
is_a: CL:0002494 ! cardiocyte
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0002099 ! cardiac septum
relationship: part_of UBERON:0002099 ! cardiac septum
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-06-24T23:17:07Z

[Term]
id: CL:2000029
name: central nervous system neuron
def: "Any neuron that is part of a central nervous system." [GOC:TermGenie]
is_a: CL:0000540 ! neuron
intersection_of: CL:0000540 ! neuron
intersection_of: has_soma_location UBERON:0001017 ! central nervous system
relationship: has_soma_location UBERON:0001017 ! central nervous system
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-06-25T01:17:43Z

[Term]
id: CL:2000032
name: peripheral nervous system neuron
def: "A neuron that is part of a peripheral nervous system." [GOC:TermGenie, ISBN:0721662544]
subset: cellxgene_subset
synonym: "peripheral neuron" EXACT []
synonym: "PNS neuron" EXACT []
xref: FMA:84664
is_a: CL:0000540 ! neuron
intersection_of: CL:0000540 ! neuron
intersection_of: has_soma_location UBERON:0000010 ! peripheral nervous system
relationship: has_soma_location UBERON:0000010 ! peripheral nervous system
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-06-25T02:28:17Z

[Term]
id: CL:2000040
name: bladder microvascular endothelial cell
def: "Any microvascular endothelial cell that is part of a urinary bladder." [GOC:TermGenie]
subset: human_reference_atlas
is_a: CL:1001319 ! bladder cell
is_a: CL:2000008 ! microvascular endothelial cell
intersection_of: CL:2000008 ! microvascular endothelial cell
intersection_of: part_of UBERON:0001255 ! urinary bladder
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2014-07-09T00:04:47Z

[Term]
id: CL:2000042
name: embryonic fibroblast
def: "Any fibroblast that is part of a embryo." [GOC:TermGenie]
subset: cellxgene_subset
is_a: CL:0000057 ! fibroblast
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0000922 ! embryo
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-07-09T00:12:00Z

[Term]
id: CL:2000044
name: brain microvascular endothelial cell
def: "Any microvascular endothelial cell that is part of a brain." [GOC:TermGenie]
is_a: CL:0002319 ! neural cell
is_a: CL:2000008 ! microvascular endothelial cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:2000008 ! microvascular endothelial cell
intersection_of: part_of UBERON:0000955 ! brain
relationship: part_of UBERON:0000955 ! brain
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-07-09T00:24:53Z

[Term]
id: CL:2000046
name: ventricular cardiac muscle cell
def: "Any cardiac muscle cell that is part of a cardiac ventricle." [GOC:TermGenie]
subset: cellxgene_subset
is_a: CL:0000746 ! cardiac muscle cell
intersection_of: CL:0000746 ! cardiac muscle cell
intersection_of: part_of UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0002082 ! cardiac ventricle
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-08-12T20:50:28Z

[Term]
id: CL:2000047
name: brainstem motor neuron
def: "Any motor neuron that is part of a brainstem." [GOC:TermGenie]
is_a: CL:0000100 ! motor neuron
is_a: CL:2000029 ! central nervous system neuron
intersection_of: CL:0000100 ! motor neuron
intersection_of: has_soma_location UBERON:0002298 ! brainstem
relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: has_soma_location UBERON:0002298 ! brainstem
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-02T23:52:53Z

[Term]
id: CL:2000051
name: splenic fibroblast
def: "Any fibroblast that is part of a spleen." [GOC:TermGenie]
is_a: CL:0000057 ! fibroblast
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0002106 ! spleen
relationship: part_of UBERON:0002106 ! spleen
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-06T18:58:47Z

[Term]
id: CL:2000052
name: umbilical artery endothelial cell
def: "Any endothelial cell of artery that is part of a umbilical cord." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=8010
is_a: CL:0000349 ! extraembryonic cell
is_a: CL:1000413 ! endothelial cell of artery
intersection_of: CL:1000413 ! endothelial cell of artery
intersection_of: part_of UBERON:0002331 ! umbilical cord
relationship: part_of UBERON:0002331 ! umbilical cord
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-06T19:01:48Z

[Term]
id: CL:2000053
name: splenic endothelial cell
def: "Any endothelial cell that is part of a spleen." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=5500
subset: human_reference_atlas
is_a: CL:0000115 ! endothelial cell
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0002106 ! spleen
relationship: part_of UBERON:0002106 ! spleen
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2014-10-06T19:06:04Z

[Term]
id: CL:2000055
name: liver dendritic cell
def: "Any dendritic cell that is part of a liver." [GOC:TermGenie]
comment: http://www.jleukbio.org/content/66/2/322.abstract
subset: cellxgene_subset
synonym: "hepatic dendritic cell" EXACT []
is_a: CL:0000451 ! dendritic cell
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000451 ! dendritic cell
intersection_of: part_of UBERON:0002107 ! liver
relationship: part_of UBERON:0002107 ! liver
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-06T19:16:11Z

[Term]
id: CL:2000061
name: placental amniotic mesenchymal stromal cell
def: "Any mesenchymal stem cell that is part of a placenta." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7140
subset: human_reference_atlas
is_a: CL:0000134 ! mesenchymal stem cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000134 ! mesenchymal stem cell
intersection_of: part_of UBERON:0001987 ! placenta
relationship: part_of UBERON:0001987 ! placenta
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2014-10-07T17:51:11Z

[Term]
id: CL:2000063
name: ovarian fibroblast
def: "Any fibroblast that is part of a female gonad." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7330
is_a: CL:0000057 ! fibroblast
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0000992 ! ovary
relationship: part_of UBERON:0000992 ! ovary
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-07T17:57:42Z

[Term]
id: CL:2000064
name: ovarian surface epithelial cell
def: "Any epithelial cell that is part of a female gonad." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7310
subset: cellxgene_subset
is_a: CL:0000066 ! epithelial cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0000992 ! ovary
relationship: part_of UBERON:0000992 ! ovary
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-07T17:59:13Z

[Term]
id: CL:2000065
name: ovarian microvascular endothelial cell
def: "Any microvascular endothelial cell that is part of a female urethra." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7300
is_a: CL:1000296 ! epithelial cell of urethra
is_a: CL:2000008 ! microvascular endothelial cell
intersection_of: CL:2000008 ! microvascular endothelial cell
intersection_of: part_of UBERON:0001334 ! female urethra
relationship: part_of UBERON:0001334 ! female urethra
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-07T18:18:01Z

[Term]
id: CL:2000066
name: cardiac ventricle fibroblast
def: "Any fibroblast that is part of a cardiac ventricle." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6310
subset: human_reference_atlas
is_a: CL:0002548 ! fibroblast of cardiac tissue
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0002082 ! cardiac ventricle
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2014-10-07T18:35:38Z

[Term]
id: CL:2000067
name: cardiac atrium fibroblast
def: "Any fibroblast that is part of a cardiac atrium." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6320
subset: human_reference_atlas
is_a: CL:0002548 ! fibroblast of cardiac tissue
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0002081 ! cardiac atrium
relationship: part_of UBERON:0002081 ! cardiac atrium
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2014-10-07T18:36:54Z

[Term]
id: CL:2000068
name: pericardium fibroblast
def: "Any fibroblast that is part of a pericardium." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6430
is_a: CL:0000057 ! fibroblast
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0002407 ! pericardium
relationship: part_of UBERON:0002407 ! pericardium
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-07T18:38:06Z

[Term]
id: CL:2000069
name: gallbladder fibroblast
def: "Any fibroblast that is part of a gallbladder." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=5430
is_a: CL:0000057 ! fibroblast
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0002110 ! gallbladder
relationship: part_of UBERON:0002110 ! gallbladder
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-07T18:41:43Z

[Term]
id: CL:2000070
name: optic choroid fibroblast
def: "Any fibroblast that is part of a optic choroid." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6620
is_a: CL:0000057 ! fibroblast
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0001776 ! optic choroid
relationship: part_of UBERON:0001776 ! optic choroid
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-07T18:50:43Z

[Term]
id: CL:2000072
name: adipose microvascular endothelial cell
def: "Any microvascular endothelial cell that is part of a adipose tissue." [GOC:TermGenie]
comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7200
is_a: CL:0002320 ! connective tissue cell
is_a: CL:2000008 ! microvascular endothelial cell
intersection_of: CL:2000008 ! microvascular endothelial cell
intersection_of: part_of UBERON:0001013 ! adipose tissue
relationship: part_of UBERON:0001013 ! adipose tissue
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-10-07T22:13:45Z

[Term]
id: CL:2000073
name: migratory cardiac neural crest cell
def: "Any migratory neural crest cell that is part of a cardiac neural crest." [GOC:TermGenie]
synonym: "cardiac neural crest cell" EXACT [PMID:33060096]
is_a: CL:0000333 ! migratory neural crest cell
intersection_of: CL:0000333 ! migratory neural crest cell
intersection_of: part_of UBERON:0000095 ! cardiac neural crest
relationship: part_of UBERON:0000095 ! cardiac neural crest
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-11-05T01:18:43Z

[Term]
id: CL:2000074
name: splenocyte
def: "Any leukocyte that is part of a spleen." [GOC:TermGenie]
comment: Splenocytes is a vague term that refers to any one of the different white blood cell types in the spleen. This name is seen many references as such and is not explained further, necessitating a need for this terminology.
is_a: CL:0000738 ! leukocyte
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000738 ! leukocyte
intersection_of: part_of UBERON:0002106 ! spleen
relationship: part_of UBERON:0002106 ! spleen
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-11-05T01:26:50Z

[Term]
id: CL:2000080
name: mesenchymal stem cell of abdominal adipose tissue
def: "Any mesenchymal stem cell of adipose tissue that is part of an abdomen." [GOC:TermGenie]
synonym: "mesenchymal stem cell of abdominal adipose" EXACT []
is_a: CL:0002570 ! mesenchymal stem cell of adipose tissue
intersection_of: CL:0002570 ! mesenchymal stem cell of adipose tissue
intersection_of: part_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0000916 ! abdomen
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-12-02T19:10:34Z

[Term]
id: CL:2000085
name: mononuclear cell of umbilical cord
def: "Any mononuclear cell that is part of a umbilical cord." [GOC:TermGenie]
is_a: CL:0000349 ! extraembryonic cell
is_a: CL:0000842 ! mononuclear cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000842 ! mononuclear cell
intersection_of: part_of UBERON:0002331 ! umbilical cord
relationship: part_of UBERON:0002331 ! umbilical cord
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2014-12-02T20:14:16Z

[Term]
id: CL:2000091
name: endometrial microvascular endothelial cell
def: "Any microvascular endothelial cell that is part of a endometrial blood vessel." [GOC:TermGenie]
subset: human_reference_atlas
is_a: CL:0009095 ! endothelial cell of uterus
is_a: CL:2000008 ! microvascular endothelial cell
intersection_of: CL:2000008 ! microvascular endothelial cell
intersection_of: part_of UBERON:0015172 ! endometrial blood vessel
relationship: part_of UBERON:0015172 ! endometrial blood vessel
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
property_value: RO:0002175 NCBITaxon:9606
creation_date: 2015-03-31T21:02:36Z

[Term]
id: CL:2000095
name: cord blood hematopoietic stem cell
def: "Any hematopoietic stem cell that is part of a umbilical cord blood." [GOC:TermGenie]
subset: cellxgene_subset
is_a: CL:0002246 ! peripheral blood stem cell
is_a: CL:0002352 ! gestational hematopoietic stem cell
intersection_of: CL:0000037 ! hematopoietic stem cell
intersection_of: part_of UBERON:0012168 ! umbilical cord blood
relationship: part_of UBERON:0012168 ! umbilical cord blood
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q35563349
creation_date: 2015-05-26T18:58:34Z

[Term]
id: CL:3000000
name: ciliated epithelial cell of esophagus
def: "A ciliated epithelial cell of the esophagus." [GOC:CellBLAST, PMID:29802404]
is_a: CL:0000067 ! ciliated epithelial cell
is_a: CL:0002252 ! epithelial cell of esophagus
intersection_of: CL:0000067 ! ciliated epithelial cell
intersection_of: part_of UBERON:0001976 ! epithelium of esophagus
relationship: part_of UBERON:0001976 ! epithelium of esophagus
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q97529981
creation_date: 2019-02-09T16:40:30Z

[Term]
id: CL:3000004
name: peripheral sensory neuron
def: "Peripheral sensory neuron." [GOC:CellBLAST, PMID:30096314]
is_a: CL:0000101 ! sensory neuron
is_a: CL:2000032 ! peripheral nervous system neuron
intersection_of: CL:2000032 ! peripheral nervous system neuron
intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception
property_value: http://purl.org/dc/terms/contributor https://www.wikidata.org/entity/Q97529981
creation_date: 2019-02-25T19:34:33Z

[Term]
id: CL:4023072
name: brain vascular cell
def: "A cell that is part of the brain vasculature." [DOI:10.1101/2022.10.12.511898]
subset: human_reference_atlas
is_a: CL:0002319 ! neural cell
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0008998 ! vasculature of brain
relationship: part_of UBERON:0008998 ! vasculature of brain
property_value: http://purl.org/dc/terms/contributor http://orcid.org/0000-0001-7258-9596
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:4023079
name: midbrain-derived inhibitory neuron
def: "A GABAergic inhibitory neuron that is derived from the midbrain." [DOI:10.1101/2022.10.12.511898]
subset: human_reference_atlas
is_a: CL:0000540 ! neuron
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: CL:0000540 ! neuron
intersection_of: develops_from UBERON:0001891 ! midbrain
relationship: develops_from UBERON:0001891 ! midbrain
property_value: http://purl.org/dc/terms/contributor http://orcid.org/0000-0001-7258-9596
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:4023168
name: somatosensory neuron
def: "A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli." [PMID:22865660]
is_a: CL:0000540 ! neuron
intersection_of: CL:0000540 ! neuron
intersection_of: part_of UBERON:0003942 ! somatosensory system
relationship: part_of UBERON:0003942 ! somatosensory system
property_value: http://purl.org/dc/terms/contributor http://orcid.org/0000-0001-7258-9596

[Term]
id: CL:4028001
name: pulmonary capillary endothelial cell
def: "Any capillary endothelial cell that is part of a lung." []
synonym: "lung capillary endothelial cell" EXACT []
is_a: CL:0002144 ! capillary endothelial cell
is_a: CL:2000016 ! lung microvascular endothelial cell
intersection_of: CL:0002144 ! capillary endothelial cell
intersection_of: part_of UBERON:0002048 ! lung
relationship: part_of UBERON:0016405 ! pulmonary capillary
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-3293-5463
creation_date: 2021-11-23T02:31:40Z

[Term]
id: CL:4030025
name: renal cortical fibroblast
def: "A fibroblast that is located in the renal cortical interstitium." [PMID:10559635]
comment: Renal cortical fibroblasts have key roles in mediating intercellular communication with neighboring/infiltrating cells and extracellular matrix and maintenance of renal tissue architecture. They additionally have an endocrine function in the production of epoetin. {xref="PMID:16230044"}
synonym: "kidney cortical fibroblast" EXACT []
is_a: CL:1000681 ! kidney cortex interstitial cell
is_a: CL:1000692 ! kidney interstitial fibroblast
intersection_of: CL:0000057 ! fibroblast
intersection_of: part_of UBERON:0005270 ! renal cortex interstitium
property_value: http://purl.org/dc/terms/date "2022-07-05T15:50:17Z" xsd:dateTime

[Term]
id: CL:4030029
name: blood lymphocyte
def: "A lymphocyte located in blood." [https://orcid.org/0000-0001-9990-8331]
subset: blood_and_immune_upper_slim
is_a: CL:0000542 ! lymphocyte
is_a: CL:2000001 ! peripheral blood mononuclear cell
intersection_of: CL:0000542 ! lymphocyte
intersection_of: part_of UBERON:0000178 ! blood
property_value: http://purl.org/dc/terms/date "2022-11-04T14:40:00Z" xsd:dateTime

[Term]
id: CL:4030031
name: interstitial cell
def: "Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. \"Interstitial cell\" is a morphological term and refers to a variety of cells with differing origins and phenotypes." [PMID:24987007]
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: part_of UBERON:0005169 ! interstitial tissue
relationship: part_of UBERON:0005169 ! interstitial tissue
property_value: http://purl.org/dc/terms/date "2022-11-30T14:35:08Z" xsd:dateTime

[Term]
id: CL:4030034
name: respiratory ciliated cell
def: "A ciliated cell of the respiratory system. Ciliated cells are present in airway epithelium." [PMID:18757316, PMID:21364219]
synonym: "ciliated cell of the respiratory tract" EXACT []
is_a: CL:0000064 ! ciliated cell
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: CL:0000064 ! ciliated cell
intersection_of: part_of UBERON:0004802 ! respiratory tract epithelium
relationship: part_of UBERON:0004802 ! respiratory tract epithelium
property_value: http://purl.org/dc/terms/date "2023-01-25T11:06:01Z" xsd:dateTime

[Term]
id: CL:4030040
name: endometrial ciliated epithelial cell
def: "A ciliated cell of the endometrial epithelium. The cilia of this cell type help move mucus from glandular tissue of the endometrium." [doi:10.1038/s41591-020-1040-z, https://www.proteinatlas.org/humanproteome/single+cell+type/Glandular+epithelial+cells#endometrialciliatedcells]
comment: In human samples, the expression of FOXJ1 protein, a regulator for motile cilia with epithelial lineage identity, has been noted. {xref="ttps://www.nature.com/articles/s41591-020-1040-z"}
synonym: "ciliated cell of the endometrium" EXACT []
synonym: "ciliated cell of the uterus" BROAD []
synonym: "endometrium ciliated epithelial cell" EXACT []
synonym: "uterine ciliated cell" BROAD []
is_a: CL:0000067 ! ciliated epithelial cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000064 ! ciliated cell
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0004811 ! endometrium epithelium
relationship: part_of UBERON:0004811 ! endometrium epithelium
property_value: http://purl.org/dc/terms/date "2023-02-09T11:25:14Z" xsd:dateTime

[Term]
id: CL:4030066
name: ureteric bud cell
def: "An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion." [PMID:17133361, PMID:24183650, PMID:9374839]
synonym: "UB cell" RELATED OMO:0003000 [PMID:24183650]
is_a: CL:0000068 ! duct epithelial cell
is_a: CL:0002518 ! kidney epithelial cell
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: CL:0000066 ! epithelial cell
intersection_of: part_of UBERON:0000084 ! ureteric bud
relationship: part_of UBERON:0000084 ! ureteric bud
relationship: participates_in GO:2001013 {xref="PMID:9374839"} ! epithelial cell proliferation involved in renal tubule morphogenesis
property_value: http://purl.org/dc/terms/contributor "https://orcid.org/0000-0002-1425-877X" xsd:string
property_value: http://purl.org/dc/terms/date "2023-10-13T11:22:42Z" xsd:dateTime

[Term]
id: CL:4033008
name: vein endothelial cell of respiratory system
def: "A(n) vein endothelial cell that is part of a(n) respiratory system." [PMID:34030460]
subset: human_reference_atlas
is_a: CL:0002543 ! vein endothelial cell
intersection_of: CL:0002543 ! vein endothelial cell
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0001004 ! respiratory system
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:4033018
name: lung megakaryocyte
def: "A megakaryocyte that is resident in the lung connective tissue." [PMID:33351116]
subset: human_reference_atlas
synonym: "lung MKs" RELATED OMO:0003004 [PMID:33351116]
synonym: "lung resident megakaryocyte" EXACT [PMID:36524131]
synonym: "lung-resident megakaryocyte" EXACT [PMID:36524131]
synonym: "MKL" RELATED OMO:0003000 [PMID:36524131]
is_a: CL:0000556 ! megakaryocyte
is_a: CL:0002320 ! connective tissue cell
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: CL:0000556 ! megakaryocyte
intersection_of: part_of UBERON:0000114 ! lung connective tissue
relationship: part_of UBERON:0000114 ! lung connective tissue
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-9185-3994
property_value: http://purl.org/dc/terms/date "2023-03-16T11:31:23Z" xsd:dateTime
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: CL:4033050
name: catecholaminergic neuron
def: "A neuron that releases catecholamine as a neurotransmitter." [ISBN:0521442516, PMID:12094209]
comment: Frequently used when describing the developing nervous system in zebrafish. A catecholaminergic neuron expresses tyrosine hydroxylase (TH), tyrosine hydroxylase 2 (TH2), aromatic amino acid decarboxylase (AADC), dopamine b-hydroxylase (DBH), and phenylethanolamine-N-methyl transferase (PEMT), which are enzymes necessary for catecholamine synthesis. {xref="https://orcid.org/0000-0002-2244-7917", xref="PMID:12128258", xref="PMID:10191060", xref="PMID:34880760"}
is_a: CL:0000151 ! secretory cell
is_a: CL:0000540 ! neuron
intersection_of: CL:0000540 ! neuron
intersection_of: capable_of GO:0160043 ! catecholamine secretion, neurotransmission
relationship: capable_of GO:0160043 ! catecholamine secretion, neurotransmission
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/date "2023-05-18T12:07:45Z" xsd:dateTime

[Term]
id: CL:4033054
name: perivascular cell
def: "A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics." [PMID:24928499, PMID:27889329]
is_a: CL:0000000 ! cell
intersection_of: CL:0000000 ! cell
intersection_of: adjacent_to UBERON:0002049 ! vasculature
relationship: adjacent_to UBERON:0002049 ! vasculature
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/date "2023-08-22T13:40:28Z" xsd:dateTime

[Term]
id: CL:4033061
name: endothelial cell of central vein of liver
def: "An endothelial cell that is part of a central vein of liver." [PMID:28287163]
synonym: "endothelial cell of central vein" BROAD [PMID:28287163]
is_a: CL:0000115 ! endothelial cell
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: CL:0000115 ! endothelial cell
intersection_of: part_of UBERON:0006841 ! central vein of liver
relationship: part_of UBERON:0006841 ! central vein of liver
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489

[Term]
id: CL:4040004
name: mesenchymal stem cell of orbital adipose tissue
def: "Any mesenchymal stem cell of adipose tissue that is part of an orbital region." [https://orcid.org/0000-0002-0819-0473]
synonym: "OAMSC" EXACT [PMID:31377878]
synonym: "orbital adipose-derived mesenchymal stem cell" EXACT [PMID:31377878]
synonym: "Orbital ASCs" EXACT [PMID:30210548]
is_a: CL:0002570 ! mesenchymal stem cell of adipose tissue
intersection_of: CL:0002570 ! mesenchymal stem cell of adipose tissue
intersection_of: part_of UBERON:0004088 ! orbital region
relationship: part_of UBERON:0004088 ! orbital region
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2023-09-18T10:43:00Z" xsd:dateTime

[Term]
id: GO:0000003
name: reproduction
namespace: biological_process
alt_id: GO:0019952
alt_id: GO:0050876
def: "The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms." [GOC:go_curators, GOC:isa_complete, GOC:jl, ISBN:0198506732]
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_pir
subset: goslim_plant
synonym: "reproductive physiological process" EXACT []
xref: Wikipedia:Reproduction
is_a: GO:0008150 ! biological process

[Term]
id: GO:0000011
name: vacuole inheritance
namespace: biological_process
def: "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton." [GOC:mcc, PMID:10873824, PMID:14616069]
is_a: GO:0007033 ! vacuole organization
is_a: GO:0048308 ! organelle inheritance
intersection_of: GO:0048308 ! organelle inheritance
intersection_of: results_in_distribution_of GO:0005773 ! vacuole
relationship: results_in_distribution_of GO:0005773 ! vacuole
property_value: RO:0002161 NCBITaxon:4896

[Term]
id: GO:0000070
name: mitotic sister chromatid segregation
namespace: biological_process
alt_id: GO:0016359
def: "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, GOC:jl]
subset: goslim_pombe
synonym: "mitotic chromosome segregation" EXACT []
synonym: "mitotic sister-chromatid adhesion release" NARROW []
is_a: GO:0000819 ! sister chromatid segregation
is_a: GO:1903047 ! mitotic cell cycle process
intersection_of: GO:0098813 ! nuclear chromosome segregation
intersection_of: part_of GO:0140014 ! mitotic nuclear division
relationship: part_of GO:0140014 ! mitotic nuclear division

[Term]
id: GO:0000139
name: Golgi membrane
namespace: cellular_component
def: "The lipid bilayer surrounding any of the compartments of the Golgi apparatus." [GOC:mah]
synonym: "Golgi apparatus membrane" EXACT []
is_a: GO:0098588 ! bounding membrane of organelle
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0005794 ! Golgi apparatus
relationship: bounding_layer_of GO:0005794 ! Golgi apparatus
relationship: part_of GO:0005794 ! Golgi apparatus

[Term]
id: GO:0000226
name: microtubule cytoskeleton organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah]
subset: goslim_pombe
synonym: "microtubule cytoskeleton organisation" EXACT [GOC:mah]
synonym: "microtubule cytoskeleton organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0007010 ! cytoskeleton organization
is_a: GO:0007017 ! microtubule-based process
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0015630 ! microtubule cytoskeleton
relationship: results_in_organization_of GO:0015630 ! microtubule cytoskeleton
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23114" xsd:anyURI
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23195" xsd:anyURI

[Term]
id: GO:0000228
name: nuclear chromosome
namespace: cellular_component
def: "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." [GOC:dph, GOC:mah]
subset: goslim_chembl
subset: goslim_generic
synonym: "nuclear interphase chromosome" NARROW []
is_a: GO:0005694 ! chromosome
intersection_of: GO:0005694 ! chromosome
intersection_of: part_of GO:0005634 ! nucleus
relationship: part_of GO:0031981 ! nuclear lumen

[Term]
id: GO:0000271
name: polysaccharide biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:go_curators]
synonym: "glycan biosynthesis" EXACT []
synonym: "glycan biosynthetic process" EXACT []
synonym: "polysaccharide anabolism" EXACT []
synonym: "polysaccharide biosynthesis" EXACT []
synonym: "polysaccharide formation" EXACT []
synonym: "polysaccharide synthesis" EXACT []
is_a: GO:0005976 ! polysaccharide metabolic process
is_a: GO:0009059 ! macromolecule biosynthetic process
is_a: GO:0016051 ! carbohydrate biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:18154 ! polysaccharide
relationship: has_primary_output CHEBI:18154 ! polysaccharide

[Term]
id: GO:0000272
name: polysaccharide catabolic process
namespace: biological_process
alt_id: GO:0044244
def: "The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [PMID:33139480]
synonym: "multicellular organismal polysaccharide catabolic process" NARROW []
synonym: "polysaccharide breakdown" EXACT []
synonym: "polysaccharide catabolism" EXACT []
synonym: "polysaccharide degradation" EXACT []
is_a: GO:0005976 ! polysaccharide metabolic process
is_a: GO:0009057 ! macromolecule catabolic process
is_a: GO:0016052 ! carbohydrate catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:18154 ! polysaccharide
relationship: has_primary_input CHEBI:18154 ! polysaccharide

[Term]
id: GO:0000278
name: mitotic cell cycle
namespace: biological_process
alt_id: GO:0007067
def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." [GOC:mah, ISBN:0815316194, Reactome:69278]
comment: Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_yeast
synonym: "mitosis" RELATED []
xref: Wikipedia:Mitosis
is_a: GO:0007049 ! cell cycle
intersection_of: GO:0007049 ! cell cycle
intersection_of: has_part GO:0140014 ! mitotic nuclear division
relationship: has_part GO:0140014 ! mitotic nuclear division
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota

[Term]
id: GO:0000280
name: nuclear division
namespace: biological_process
def: "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." [GOC:mah]
subset: goslim_pir
synonym: "karyokinesis" RELATED []
is_a: GO:0048285 ! organelle fission
intersection_of: GO:0048285 ! organelle fission
intersection_of: results_in_fission_of GO:0005634 ! nucleus
relationship: results_in_fission_of GO:0005634 ! nucleus

[Term]
id: GO:0000313
name: organellar ribosome
namespace: cellular_component
def: "A ribosome contained within a subcellular membrane-bounded organelle." [GOC:mah, GOC:mcc]
is_a: GO:0005840 ! ribosome
intersection_of: GO:0005840 ! ribosome
intersection_of: part_of GO:0043226 ! organelle
relationship: part_of GO:0043226 ! organelle

[Term]
id: GO:0000578
name: embryonic axis specification
namespace: biological_process
def: "The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo." [GOC:dph, GOC:go_curators, GOC:sdb_2009, GOC:tb]
synonym: "embryonic axis determination" RELATED []
is_a: GO:0009798 ! axis specification
is_a: GO:0009880 ! embryonic pattern specification

[Term]
id: GO:0000740
name: nuclear membrane fusion
namespace: biological_process
def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus." [GOC:elh]
is_a: GO:0071763 ! nuclear membrane organization
is_a: GO:0090174 ! organelle membrane fusion
intersection_of: GO:0061025 ! membrane fusion
intersection_of: results_in_fusion_of GO:0031965 ! nuclear membrane
relationship: results_in_fusion_of GO:0031965 ! nuclear membrane

[Term]
id: GO:0000741
name: karyogamy
namespace: biological_process
alt_id: GO:0007335
def: "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei." [GOC:elh]
synonym: "nuclear fusion" EXACT []
synonym: "nuclear fusion during karyogamy" EXACT []
xref: Wikipedia:Karyogamy
is_a: GO:0006997 ! nucleus organization
is_a: GO:0048284 ! organelle fusion
intersection_of: GO:0048284 ! organelle fusion
intersection_of: results_in_fusion_of GO:0005634 ! nucleus
relationship: part_of GO:0006997 ! nucleus organization
relationship: results_in_fusion_of GO:0005634 ! nucleus

[Term]
id: GO:0000768
name: syncytium formation by plasma membrane fusion
namespace: biological_process
def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mtg_muscle, GOC:tb]
synonym: "cell fusion" BROAD []
is_a: GO:0006949 ! syncytium formation
is_a: GO:0140253 ! cell-cell fusion
intersection_of: GO:0006949 ! syncytium formation
intersection_of: has_part GO:0045026 ! plasma membrane fusion

[Term]
id: GO:0000785
name: chromatin
namespace: cellular_component
alt_id: GO:0000789
alt_id: GO:0000790
alt_id: GO:0005717
def: "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome." [GOC:elh, PMID:20404130]
comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.
synonym: "chromosome scaffold" RELATED []
synonym: "cytoplasmic chromatin" NARROW []
synonym: "nuclear chromatin" NARROW []
xref: NIF_Subcellular:sao1615953555
is_a: GO:0032993 ! protein-DNA complex
relationship: part_of GO:0005694 ! chromosome

[Term]
id: GO:0000792
name: heterochromatin
namespace: cellular_component
alt_id: GO:0005720
alt_id: GO:0035328
def: "A compact and highly condensed form of chromatin that is refractory to transcription." [PMID:32017156]
synonym: "nuclear heterochromatin" NARROW []
synonym: "transcriptionally inactive chromatin" EXACT []
synonym: "transcriptionally silent chromatin" EXACT []
xref: NIF_Subcellular:sao581845896
xref: Wikipedia:Heterochromatin
is_a: GO:0000785 ! chromatin
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22355" xsd:anyURI

[Term]
id: GO:0000819
name: sister chromatid segregation
namespace: biological_process
def: "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets." [GOC:ai, GOC:elh]
is_a: GO:0051276 ! chromosome organization
is_a: GO:0098813 ! nuclear chromosome segregation

[Term]
id: GO:0000902
name: cell morphogenesis
namespace: biological_process
alt_id: GO:0007148
alt_id: GO:0045790
alt_id: GO:0045791
def: "The developmental process in which the size or shape of a cell is generated and organized." [GOC:clt, GOC:dph, GOC:go_curators, GOC:tb]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_yeast
synonym: "cellular morphogenesis" EXACT []
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of CL:0000000 ! cell
relationship: results_in_morphogenesis_of CL:0000000 ! cell

[Term]
id: GO:0001101
name: response to acid chemical
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." [GOC:go_curators, GOC:rn]
comment: This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead.
subset: gocheck_do_not_manually_annotate
synonym: "response to acid" BROAD []
synonym: "response to acid anion" RELATED []
synonym: "response to oxoanion" RELATED []
is_a: GO:0042221 ! response to chemical

[Term]
id: GO:0001501
name: skeletal system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)." [GOC:dph, GOC:jid, GOC:tb]
synonym: "skeletal development" EXACT []
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001434 ! skeletal system
relationship: results_in_development_of UBERON:0001434 ! skeletal system

[Term]
id: GO:0001503
name: ossification
namespace: biological_process
def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:mtg_mpo, PMID:17572649]
comment: Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'.
synonym: "bone biosynthesis" EXACT []
synonym: "bone formation" EXACT []
synonym: "osteogenesis" EXACT []
xref: Wikipedia:Ossification
is_a: GO:0032501 ! multicellular organismal process
intersection_of: GO:0032501 ! multicellular organismal process
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001474 ! bone element
relationship: results_in_formation_of_anatomical_entity UBERON:0001474 ! bone element

[Term]
id: GO:0001508
name: action potential
namespace: biological_process
def: "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities." [GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8]
comment: Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so.
is_a: GO:0042391 ! regulation of membrane potential
property_value: RO:0002161 NCBITaxon:4895

[Term]
id: GO:0001525
name: angiogenesis
namespace: biological_process
def: "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels." [ISBN:0878932453]
synonym: "blood vessel formation from pre-existing blood vessels" EXACT systematic_synonym []
xref: Wikipedia:Angiogenesis
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001981 ! blood vessel
relationship: part_of GO:0048514 ! blood vessel morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001981 ! blood vessel

[Term]
id: GO:0001539
name: cilium or flagellum-dependent cell motility
namespace: biological_process
def: "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella." [GOC:cilia, GOC:hjd, GOC:krc]
comment: Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "ciliary or bacterial-type flagellar motility" RELATED []
synonym: "ciliary/flagellar motility" EXACT []
is_a: GO:0048870 ! cell motility

[Term]
id: GO:0001553
name: luteinization
namespace: biological_process
def: "The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation." [https://www.ncbi.nlm.nih.gov/books/NBK279054/]
synonym: "luteal phase" RELATED []
xref: Wikipedia:Luteal_phase
xref: Wikipedia:Luteinization
is_a: GO:0022602 ! ovulation cycle process
relationship: part_of GO:0008585 ! female gonad development

[Term]
id: GO:0001555
name: oocyte growth
namespace: biological_process
def: "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [https://www.ncbi.nlm.nih.gov/books/NBK279054/]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0048588 ! developmental cell growth
intersection_of: GO:0040007 ! growth
intersection_of: results_in_growth_of CL:0000023 ! oocyte
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of GO:0048599 ! oocyte development
relationship: results_in_growth_of CL:0000023 ! oocyte

[Term]
id: GO:0001556
name: oocyte maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization." [GOC:devbiol, https://www.ncbi.nlm.nih.gov/books/NBK279054/]
xref: Wikipedia:Oocyte_maturation
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0048469 ! cell maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000023 ! oocyte
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of GO:0048599 ! oocyte development
relationship: results_in_maturation_of CL:0000023 ! oocyte

[Term]
id: GO:0001558
name: regulation of cell growth
namespace: biological_process
def: "Any process that modulates the frequency, rate, extent or direction of cell growth." [GOC:go_curators]
is_a: GO:0040008 ! regulation of growth
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016049 ! cell growth
relationship: regulates GO:0016049 ! cell growth

[Term]
id: GO:0001568
name: blood vessel development
namespace: biological_process
def: "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood." [GOC:hjd, UBERON:0001981]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001981 ! blood vessel
relationship: part_of GO:0001944 ! vasculature development
relationship: results_in_development_of UBERON:0001981 ! blood vessel

[Term]
id: GO:0001569
name: branching involved in blood vessel morphogenesis
namespace: biological_process
def: "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system." [GOC:dph]
synonym: "patterning of blood vessels" BROAD [GOC:dph]
is_a: GO:0048754 ! branching morphogenesis of an epithelial tube
intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube
intersection_of: part_of GO:0048514 ! blood vessel morphogenesis
relationship: part_of GO:0001525 ! angiogenesis

[Term]
id: GO:0001570
name: vasculogenesis
namespace: biological_process
def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes." [PMID:8999798]
synonym: "vascular morphogenesis" EXACT []
xref: Wikipedia:Vasculogenesis
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001981 ! blood vessel
relationship: part_of GO:0048514 ! blood vessel morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001981 ! blood vessel

[Term]
id: GO:0001578
name: microtubule bundle formation
namespace: biological_process
def: "A process that results in a parallel arrangement of microtubules." [GOC:dph]
synonym: "microtubule bundling" EXACT []
is_a: GO:0000226 ! microtubule cytoskeleton organization
relationship: has_participant GO:0005874 ! microtubule
relationship: results_in_formation_of_anatomical_entity GO:0097427 ! microtubule bundle

[Term]
id: GO:0001654
name: eye development
namespace: biological_process
alt_id: GO:0042460
def: "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight." [GOC:jid, GOC:jl]
xref: Wikipedia:Eye_development
is_a: GO:0007423 ! sensory organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000970 ! eye
relationship: part_of GO:0150063 ! visual system development
relationship: results_in_development_of UBERON:0000970 ! eye

[Term]
id: GO:0001655
name: urogenital system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure." [GOC:go_curators]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004122 ! genitourinary system
relationship: has_part GO:0072001 ! renal system development
relationship: results_in_development_of UBERON:0004122 ! genitourinary system
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22178" xsd:anyURI

[Term]
id: GO:0001656
name: metanephros development
namespace: biological_process
def: "The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:bf, ISBN:0192800752]
is_a: GO:0001822 ! kidney development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000081 ! metanephros
relationship: results_in_development_of UBERON:0000081 ! metanephros

[Term]
id: GO:0001657
name: ureteric bud development
namespace: biological_process
def: "The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure." [GOC:go_curators]
is_a: GO:0072164 ! mesonephric tubule development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000084 ! ureteric bud
relationship: results_in_development_of UBERON:0000084 ! ureteric bud

[Term]
id: GO:0001658
name: branching involved in ureteric bud morphogenesis
namespace: biological_process
def: "The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, PMID:16916378]
synonym: "ureteric bud branching" EXACT [GOC:dph]
is_a: GO:0048754 ! branching morphogenesis of an epithelial tube
intersection_of: GO:0001763 ! morphogenesis of a branching structure
intersection_of: part_of GO:0060675 ! ureteric bud morphogenesis
relationship: part_of GO:0060675 ! ureteric bud morphogenesis

[Term]
id: GO:0001659
name: temperature homeostasis
namespace: biological_process
def: "A homeostatic process in which an organism modulates its internal body temperature." [GOC:jl]
synonym: "thermoregulation" EXACT [GOC:dph, GOC:tb]
xref: Wikipedia:Thermoregulation
is_a: GO:0048871 ! multicellular organismal-level homeostasis

[Term]
id: GO:0001666
name: response to hypoxia
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:hjd]
comment: Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.
synonym: "response to hypoxic stress" EXACT []
synonym: "response to intermittent hypoxia" NARROW []
synonym: "response to lowered oxygen tension" EXACT []
synonym: "response to sustained hypoxia" NARROW []
is_a: GO:0006950 ! response to stress
is_a: GO:0036293 ! response to decreased oxygen levels

[Term]
id: GO:0001667
name: ameboidal-type cell migration
namespace: biological_process
def: "Cell migration that is accomplished by extension and retraction of a pseudopodium." [GOC:dph]
comment: Note that this term refers to a mode of migration rather than to any particular cell type.
synonym: "ameboid cell migration" EXACT []
synonym: "amoeboid cell migration" EXACT []
synonym: "amoeboidal cell migration" EXACT []
is_a: GO:0016477 ! cell migration

[Term]
id: GO:0001669
name: acrosomal vesicle
namespace: cellular_component
def: "A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome." [ISBN:0124325653, ISBN:0198506732]
synonym: "acrosomal granule" EXACT [GOC:sart]
synonym: "acrosome" EXACT [GOC:dph]
xref: Wikipedia:Acrosome
is_a: GO:0030141 ! secretory granule
relationship: part_of CL:0000019 ! sperm

[Term]
id: GO:0001673
name: male germ cell nucleus
namespace: cellular_component
alt_id: GO:0043081
def: "The nucleus of a male germ cell, a reproductive cell in males." [CL:0000015, GOC:hjd, GOC:mtg_sensu]
synonym: "male germ-cell nucleus" EXACT []
is_a: GO:0043073 ! germ cell nucleus
intersection_of: GO:0005634 ! nucleus
intersection_of: part_of CL:0000015 ! male germ cell
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: part_of CL:0000015 ! male germ cell

[Term]
id: GO:0001674
name: female germ cell nucleus
namespace: cellular_component
alt_id: GO:0043080
def: "The nucleus of the female germ cell, a reproductive cell in females." [CL:0000021, GOC:hjd]
synonym: "female germ-cell nucleus" EXACT []
is_a: GO:0043073 ! germ cell nucleus
intersection_of: GO:0005634 ! nucleus
intersection_of: part_of CL:0000021 ! female germ cell
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: part_of CL:0000021 ! female germ cell

[Term]
id: GO:0001675
name: acrosome assembly
namespace: biological_process
def: "The formation of the acrosome from the spermatid Golgi." [GOC:dph, GOC:hjd, GOC:tb]
synonym: "acrosome formation" EXACT [GOC:dph, GOC:tb]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0010927 ! cellular component assembly involved in morphogenesis
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0033363 ! secretory granule organization
is_a: GO:0070925 ! organelle assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0001669 ! acrosomal vesicle
relationship: part_of GO:0007286 ! spermatid development
relationship: results_in_assembly_of GO:0001669 ! acrosomal vesicle

[Term]
id: GO:0001677
name: formation of translation initiation ternary complex
namespace: biological_process
def: "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:hjd]
synonym: "translation initiation ternary complex assembly" EXACT []
is_a: GO:0022618 ! protein-RNA complex assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0044207 ! translation initiation ternary complex
relationship: part_of GO:0006413 ! translational initiation
relationship: results_in_assembly_of GO:0044207 ! translation initiation ternary complex

[Term]
id: GO:0001696
name: gastric acid secretion
namespace: biological_process
def: "The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:hjd]
synonym: "hydrochloric acid secretion" NARROW []
is_a: GO:0022600 ! digestive system process
is_a: GO:0046717 ! acid secretion

[Term]
id: GO:0001700
name: embryonic development via the syncytial blastoderm
namespace: biological_process
def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster." [GOC:go_curators, GOC:mtg_sensu]
is_a: GO:0009792 ! embryo development ending in birth or egg hatching
relationship: in_taxon NCBITaxon:50557 {all_only="true"} ! Insecta
relationship: only_in_taxon NCBITaxon:50557 ! Insecta

[Term]
id: GO:0001701
name: in utero embryonic development
namespace: biological_process
def: "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus." [GOC:go_curators, GOC:mtg_sensu]
is_a: GO:0043009 ! chordate embryonic development
relationship: in_taxon NCBITaxon:32525 {all_only="true"} ! Theria <mammals>
relationship: only_in_taxon NCBITaxon:32525 ! Theria <mammals>

[Term]
id: GO:0001702
name: gastrulation with mouth forming second
namespace: biological_process
alt_id: GO:0010003
alt_id: GO:0048276
def: "A gastrulation process in which the initial invagination becomes the anus and the mouth forms second." [GOC:go_curators, GOC:mtg_sensu]
synonym: "deuterostomic gastrulation" EXACT [GOC:dph]
is_a: GO:0007369 ! gastrulation
relationship: in_taxon NCBITaxon:33511 {all_only="true"} ! Deuterostomia
relationship: only_in_taxon NCBITaxon:33511 ! Deuterostomia

[Term]
id: GO:0001704
name: formation of primary germ layer
namespace: biological_process
def: "The formation of the ectoderm, mesoderm and endoderm during gastrulation." [GOC:go_curators]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000923 ! germ layer
relationship: part_of GO:0007369 ! gastrulation
relationship: results_in_formation_of_anatomical_entity UBERON:0000923 ! germ layer

[Term]
id: GO:0001705
name: ectoderm formation
namespace: biological_process
def: "The formation of ectoderm during gastrulation." [GOC:go_curators]
is_a: GO:0001704 ! formation of primary germ layer
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000924 ! ectoderm
relationship: part_of GO:0007398 ! ectoderm development
relationship: results_in_formation_of_anatomical_entity UBERON:0000924 ! ectoderm

[Term]
id: GO:0001706
name: endoderm formation
namespace: biological_process
def: "The formation of the endoderm during gastrulation." [GOC:go_curators]
synonym: "endoblast formation" NARROW [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0001704 ! formation of primary germ layer
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000925 ! endoderm
relationship: part_of GO:0007492 ! endoderm development
relationship: results_in_formation_of_anatomical_entity UBERON:0000925 ! endoderm

[Term]
id: GO:0001707
name: mesoderm formation
namespace: biological_process
def: "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:go_curators]
is_a: GO:0001704 ! formation of primary germ layer
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000926 ! mesoderm
relationship: part_of GO:0048332 ! mesoderm morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0000926 ! mesoderm

[Term]
id: GO:0001743
name: lens placode formation
namespace: biological_process
def: "The initial developmental process that will lead to the formation of an eye." [GOC:dph]
synonym: "optic placode formation" RELATED []
is_a: GO:0060788 ! ectodermal placode formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003073 ! lens placode
relationship: part_of GO:0048598 ! embryonic morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0003073 ! lens placode

[Term]
id: GO:0001745
name: compound eye morphogenesis
namespace: biological_process
def: "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu]
synonym: "insect-type retina morphogenesis" EXACT [PMID:11735386]
is_a: GO:0048592 ! eye morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000018 ! compound eye
relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda
relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda
relationship: part_of GO:0048749 ! compound eye development
relationship: results_in_morphogenesis_of UBERON:0000018 ! compound eye

[Term]
id: GO:0001751
name: compound eye photoreceptor cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell." [GOC:go_curators]
is_a: GO:0001754 ! eye photoreceptor cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:2000019 ! compound eye photoreceptor cell
relationship: part_of GO:0001745 ! compound eye morphogenesis
relationship: results_in_acquisition_of_features_of CL:2000019 ! compound eye photoreceptor cell

[Term]
id: GO:0001754
name: eye photoreceptor cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms." [GOC:go_curators]
is_a: GO:0046530 ! photoreceptor cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000287 ! eye photoreceptor cell
relationship: part_of GO:0048592 ! eye morphogenesis
relationship: results_in_acquisition_of_features_of CL:0000287 ! eye photoreceptor cell

[Term]
id: GO:0001755
name: neural crest cell migration
namespace: biological_process
def: "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo." [GOC:ascb_2009, GOC:dph, GOC:tb, ISBN:0878932437]
is_a: GO:0090497 ! mesenchymal cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000333 ! migratory neural crest cell
relationship: part_of GO:0014032 ! neural crest cell development
relationship: results_in_movement_of CL:0000333 ! migratory neural crest cell

[Term]
id: GO:0001756
name: somitogenesis
namespace: biological_process
def: "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [ISBN:0721662544]
synonym: "formation of mesodermal clusters" EXACT systematic_synonym []
xref: Wikipedia:Somitogenesis
is_a: GO:0009952 ! anterior/posterior pattern specification
is_a: GO:0035282 ! segmentation
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002329 ! somite
relationship: part_of GO:0043009 ! chordate embryonic development
relationship: part_of GO:0061053 ! somite development
relationship: results_in_formation_of_anatomical_entity UBERON:0002329 ! somite

[Term]
id: GO:0001763
name: morphogenesis of a branching structure
namespace: biological_process
def: "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes." [ISBN:0721662544]
synonym: "branching morphogenesis" EXACT [GOC:dph]
is_a: GO:0009653 ! anatomical structure morphogenesis
is_a: GO:0032501 ! multicellular organismal process

[Term]
id: GO:0001764
name: neuron migration
namespace: biological_process
def: "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature." [CL:0000540, GOC:go_curators]
synonym: "neuron chemotaxis" EXACT []
synonym: "neuron guidance" RELATED []
synonym: "neuronal migration" EXACT []
xref: Wikipedia:Neural_development#Neuron_migration
xref: Wikipedia:Neuron_migration
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000540 ! neuron
relationship: part_of GO:0048699 ! generation of neurons
relationship: results_in_movement_of CL:0000540 ! neuron

[Term]
id: GO:0001767
name: establishment of lymphocyte polarity
namespace: biological_process
def: "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889]
synonym: "lymphocyte polarization" EXACT []
is_a: GO:0030010 ! establishment of cell polarity
intersection_of: GO:0030010 ! establishment of cell polarity
intersection_of: occurs_in CL:0000542 ! lymphocyte
relationship: occurs_in CL:0000542 ! lymphocyte
relationship: part_of GO:0046649 ! lymphocyte activation

[Term]
id: GO:0001768
name: establishment of T cell polarity
namespace: biological_process
def: "The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889]
synonym: "establishment of T lymphocyte polarity" EXACT []
synonym: "establishment of T-cell polarity" EXACT []
synonym: "establishment of T-lymphocyte polarity" EXACT []
synonym: "T cell polarization" EXACT []
synonym: "T lymphocyte polarization" EXACT []
synonym: "T-cell polarization" EXACT []
is_a: GO:0001767 ! establishment of lymphocyte polarity
intersection_of: GO:0030010 ! establishment of cell polarity
intersection_of: occurs_in CL:0000084 ! T cell
relationship: occurs_in CL:0000084 ! T cell
relationship: part_of GO:0042110 ! T cell activation

[Term]
id: GO:0001775
name: cell activation
namespace: biological_process
def: "A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell." [GOC:mgi_curators]
subset: goslim_pir
is_a: GO:0009987 ! cellular process
is_a: GO:0032501 ! multicellular organismal process
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24416" xsd:anyURI

[Term]
id: GO:0001776
name: leukocyte homeostasis
namespace: biological_process
def: "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, ISBN:0781735149]
comment: Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus.
synonym: "immune cell homeostasis" EXACT []
synonym: "leucocyte homeostasis" EXACT []
is_a: GO:0002376 ! immune system process
is_a: GO:0048872 ! homeostasis of number of cells
intersection_of: GO:0048872 ! homeostasis of number of cells
intersection_of: acts_on_population_of CL:0000738 ! leukocyte
relationship: acts_on_population_of CL:0000738 ! leukocyte
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>

[Term]
id: GO:0001777
name: T cell homeostatic proliferation
namespace: biological_process
def: "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus." [GOC:mgi_curators, ISBN:0781735149]
synonym: "resting T cell proliferation" EXACT []
synonym: "resting T-cell proliferation" EXACT []
synonym: "T lymphocyte homeostatic proliferation" EXACT []
synonym: "T-cell homeostatic proliferation" EXACT []
synonym: "T-lymphocyte homeostatic proliferation" EXACT []
is_a: GO:0042098 ! T cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000084 ! T cell
intersection_of: part_of GO:0042592 ! homeostatic process
relationship: part_of GO:0043029 ! T cell homeostasis

[Term]
id: GO:0001816
name: cytokine production
namespace: biological_process
alt_id: GO:0042032
alt_id: GO:0042089
alt_id: GO:0042107
alt_id: GO:0050663
def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
subset: gocheck_do_not_annotate
subset: goslim_pir
synonym: "cytokine biosynthetic process" NARROW []
synonym: "cytokine metabolic process" NARROW []
synonym: "cytokine secretion" NARROW []
synonym: "interferon production" NARROW [GOC:add, GOC:mah]
synonym: "interferon secretion" NARROW [GOC:add, GOC:mah]
synonym: "interleukin production" NARROW [GOC:add, GOC:mah, http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F]
synonym: "interleukin secretion" NARROW [GOC:add, GOC:mah, http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F]
is_a: GO:0010467 ! gene expression
is_a: GO:0032501 ! multicellular organismal process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19116" xsd:anyURI

[Term]
id: GO:0001817
name: regulation of cytokine production
namespace: biological_process
alt_id: GO:0042035
alt_id: GO:0050707
def: "Any process that modulates the frequency, rate, or extent of production of a cytokine." [GOC:add, ISBN:0781735149]
synonym: "regulation of cytokine anabolism" EXACT []
synonym: "regulation of cytokine biosynthesis" EXACT []
synonym: "regulation of cytokine biosynthetic process" NARROW []
synonym: "regulation of cytokine formation" EXACT []
synonym: "regulation of cytokine secretion" NARROW []
synonym: "regulation of cytokine synthesis" EXACT []
is_a: GO:0010468 ! regulation of gene expression
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001816 ! cytokine production
relationship: regulates GO:0001816 ! cytokine production

[Term]
id: GO:0001818
name: negative regulation of cytokine production
namespace: biological_process
alt_id: GO:0042036
alt_id: GO:0050710
def: "Any process that stops, prevents, or reduces the rate of production of a cytokine." [GOC:add, ISBN:0781735149]
synonym: "down regulation of cytokine biosynthetic process" EXACT []
synonym: "down regulation of cytokine production" EXACT []
synonym: "down-regulation of cytokine biosynthetic process" EXACT []
synonym: "down-regulation of cytokine production" EXACT []
synonym: "downregulation of cytokine biosynthetic process" EXACT []
synonym: "downregulation of cytokine production" EXACT []
synonym: "inhibition of cytokine biosynthetic process" NARROW []
synonym: "inhibition of cytokine production" NARROW []
synonym: "negative regulation of cytokine anabolism" EXACT []
synonym: "negative regulation of cytokine biosynthesis" EXACT []
synonym: "negative regulation of cytokine biosynthetic process" NARROW []
synonym: "negative regulation of cytokine formation" EXACT []
synonym: "negative regulation of cytokine secretion" NARROW []
synonym: "negative regulation of cytokine synthesis" EXACT []
is_a: GO:0001817 ! regulation of cytokine production
is_a: GO:0010629 ! negative regulation of gene expression
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001816 ! cytokine production
relationship: negatively_regulates GO:0001816 ! cytokine production

[Term]
id: GO:0001819
name: positive regulation of cytokine production
namespace: biological_process
alt_id: GO:0042108
alt_id: GO:0050715
def: "Any process that activates or increases the frequency, rate or extent of production of a cytokine." [GOC:add, ISBN:0781735149]
synonym: "activation of cytokine production" NARROW []
synonym: "positive regulation of cytokine biosynthetic process" NARROW []
synonym: "positive regulation of cytokine secretion" NARROW []
synonym: "stimulation of cytokine production" NARROW []
synonym: "up regulation of cytokine production" EXACT []
synonym: "up-regulation of cytokine production" EXACT []
synonym: "upregulation of cytokine production" EXACT []
is_a: GO:0001817 ! regulation of cytokine production
is_a: GO:0010628 ! positive regulation of gene expression
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001816 ! cytokine production
relationship: positively_regulates GO:0001816 ! cytokine production

[Term]
id: GO:0001820
name: serotonin secretion
namespace: biological_process
def: "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells." [GOC:ef, ISBN:0198506732, ISBN:0781735149]
synonym: "5-HT secretion" EXACT []
synonym: "5-hydroxytryptamine secretion" EXACT []
synonym: "serotonin release" RELATED [GOC:tb]
is_a: GO:0006837 ! serotonin transport
is_a: GO:0023061 ! signal release
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+)

[Term]
id: GO:0001822
name: kidney development
namespace: biological_process
def: "The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10, ISBN:0124020607, ISBN:0721662544]
synonym: "nephrogenesis" RELATED [GOC:rph]
xref: Wikipedia:Kidney_development
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002113 ! kidney
relationship: part_of GO:0072001 ! renal system development
relationship: results_in_development_of UBERON:0002113 ! kidney

[Term]
id: GO:0001823
name: mesonephros development
namespace: biological_process
def: "The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney." [GOC:dph, ISBN:0124020607, ISBN:0721662544, PMID:10535314]
synonym: "Wolffian body development" EXACT [GOC:dph]
is_a: GO:0001822 ! kidney development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000080 ! mesonephros
relationship: results_in_development_of UBERON:0000080 ! mesonephros

[Term]
id: GO:0001824
name: blastocyst development
namespace: biological_process
def: "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771]
comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'.
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000358 ! blastocyst
relationship: in_taxon NCBITaxon:32525 {all_only="true"} ! Theria <mammals>
relationship: only_in_taxon NCBITaxon:32525 ! Theria <mammals>
relationship: part_of GO:0001701 ! in utero embryonic development
relationship: results_in_development_of UBERON:0000358 ! blastocyst

[Term]
id: GO:0001825
name: blastocyst formation
namespace: biological_process
def: "The initial formation of a blastocyst from a solid ball of cells known as a morula." [GOC:dph, ISBN:0124020607, ISBN:0198542771]
comment: See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'.
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000358 ! blastocyst
relationship: part_of GO:0001824 ! blastocyst development
relationship: results_in_formation_of_anatomical_entity UBERON:0000358 ! blastocyst

[Term]
id: GO:0001826
name: inner cell mass cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771]
comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'.
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:2000020 ! inner cell mass cell
relationship: part_of GO:0001825 ! blastocyst formation
relationship: results_in_acquisition_of_features_of CL:2000020 ! inner cell mass cell

[Term]
id: GO:0001829
name: trophectodermal cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771]
comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'.
synonym: "trophectoderm cell differentiation" EXACT []
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000274 ! trophectodermal cell
relationship: part_of GO:0001825 ! blastocyst formation
relationship: results_in_acquisition_of_features_of CL:1000274 ! trophectodermal cell

[Term]
id: GO:0001831
name: trophectodermal cellular morphogenesis
namespace: biological_process
def: "The morphogenesis of trophectoderm cells." [GOC:dph, ISBN:0124020607, ISBN:0198542771]
comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.
synonym: "trophectoderm cellular morphogenesis" EXACT []
is_a: GO:0000902 ! cell morphogenesis
is_a: GO:0048598 ! embryonic morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of CL:1000274 ! trophectodermal cell
relationship: part_of GO:0001829 ! trophectodermal cell differentiation
relationship: results_in_morphogenesis_of CL:1000274 ! trophectodermal cell

[Term]
id: GO:0001832
name: blastocyst growth
namespace: biological_process
def: "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation." [GOC:dph, ISBN:0124020607, ISBN:0198542771]
comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'.
is_a: GO:0048589 ! developmental growth
intersection_of: GO:0040007 ! growth
intersection_of: results_in_growth_of UBERON:0000358 ! blastocyst
relationship: part_of GO:0001824 ! blastocyst development
relationship: results_in_growth_of UBERON:0000358 ! blastocyst

[Term]
id: GO:0001833
name: inner cell mass cell proliferation
namespace: biological_process
def: "The proliferation of cells in the inner cell mass." [GOC:dph, GOC:isa_complete, ISBN:0124020607, ISBN:0198542771]
comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'.
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:2000020 ! inner cell mass cell
relationship: acts_on_population_of CL:2000020 ! inner cell mass cell
relationship: part_of GO:0001832 ! blastocyst growth

[Term]
id: GO:0001834
name: trophectodermal cell proliferation
namespace: biological_process
def: "The proliferation of cells in the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771]
comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.
synonym: "trophectoderm cell proliferation" EXACT []
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:1000274 ! trophectodermal cell
relationship: acts_on_population_of CL:1000274 ! trophectodermal cell
relationship: part_of GO:0001832 ! blastocyst growth

[Term]
id: GO:0001837
name: epithelial to mesenchymal transition
namespace: biological_process
def: "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:dph, PMID:14701881]
synonym: "EMT" EXACT []
synonym: "epithelial-mesenchymal transition" EXACT []
synonym: "mesenchymal cell differentiation from epithelial cell" EXACT [GOC:BHF, GOC:dph, GOC:rl]
is_a: GO:0048762 ! mesenchymal cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: has_primary_input CL:0000066 ! epithelial cell
intersection_of: results_in_acquisition_of_features_of CL:0008019 ! mesenchymal cell
relationship: has_primary_input CL:0000066 ! epithelial cell

[Term]
id: GO:0001838
name: embryonic epithelial tube formation
namespace: biological_process
def: "The morphogenesis of an embryonic epithelium into a tube-shaped structure." [GOC:dph, ISBN:0824072820]
is_a: GO:0072175 ! epithelial tube formation
relationship: part_of GO:0016331 ! morphogenesis of embryonic epithelium

[Term]
id: GO:0001839
name: neural plate morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue." [GOC:dph, ISBN:0878932437]
is_a: GO:0016331 ! morphogenesis of embryonic epithelium
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003075 ! neural plate
relationship: part_of GO:0001840 ! neural plate development
relationship: results_in_morphogenesis_of UBERON:0003075 ! neural plate

[Term]
id: GO:0001840
name: neural plate development
namespace: biological_process
def: "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GOC:dph, GOC:ef, ISBN:0878932437, ISBN:0878932585]
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003075 ! neural plate
relationship: part_of GO:0043009 ! chordate embryonic development
relationship: results_in_development_of UBERON:0003075 ! neural plate

[Term]
id: GO:0001841
name: neural tube formation
namespace: biological_process
alt_id: GO:0001679
def: "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GOC:dph, ISBN:0878932437]
synonym: "neural tube morphogenesis" EXACT [GOC:dph]
synonym: "neurulation" EXACT []
xref: Wikipedia:Neurulation
is_a: GO:0001838 ! embryonic epithelial tube formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001049 ! neural tube
relationship: part_of GO:0021915 ! neural tube development
relationship: results_in_formation_of_anatomical_entity UBERON:0001049 ! neural tube

[Term]
id: GO:0001842
name: neural fold formation
namespace: biological_process
def: "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove." [GOC:dph, ISBN:0878932437]
synonym: "neural groove formation" RELATED [GOC:dph]
is_a: GO:0016331 ! morphogenesis of embryonic epithelium
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
is_a: GO:0060571 ! morphogenesis of an epithelial fold
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005062 ! neural fold
relationship: part_of GO:0014020 ! primary neural tube formation
relationship: results_in_formation_of_anatomical_entity UBERON:0005062 ! neural fold

[Term]
id: GO:0001878
name: response to yeast
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species." [PMID:14707091]
comment: defined as response to Saccharomycotina (true yeasts). This excludes fission yeast.
is_a: GO:0009620 ! response to fungus
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input NCBITaxon:147537 ! Saccharomycotina
relationship: has_primary_input NCBITaxon:147537 ! Saccharomycotina

[Term]
id: GO:0001885
name: endothelial cell development
namespace: biological_process
def: "The progression of an endothelial cell over time, from its formation to the mature structure." [GOC:dph]
is_a: GO:0002064 ! epithelial cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000115 ! endothelial cell
relationship: part_of GO:0045446 ! endothelial cell differentiation
relationship: results_in_development_of CL:0000115 ! endothelial cell

[Term]
id: GO:0001886
name: endothelial cell morphogenesis
namespace: biological_process
def: "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0003382 ! epithelial cell morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of CL:0000115 ! endothelial cell
relationship: part_of GO:0001885 ! endothelial cell development
relationship: results_in_morphogenesis_of CL:0000115 ! endothelial cell

[Term]
id: GO:0001889
name: liver development
namespace: biological_process
def: "The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes." [GOC:add, ISBN:068340007X]
is_a: GO:0048732 ! gland development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002107 ! liver
relationship: part_of GO:0061008 ! hepaticobiliary system development
relationship: results_in_development_of UBERON:0002107 ! liver

[Term]
id: GO:0001890
name: placenta development
namespace: biological_process
def: "The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X]
synonym: "placental development" EXACT []
synonym: "placentation" EXACT [GOC:dph, GOC:tb]
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001987 ! placenta
relationship: in_taxon NCBITaxon:32525 {all_only="true"} ! Theria <mammals>
relationship: only_in_taxon NCBITaxon:32525 ! Theria <mammals>
relationship: results_in_development_of UBERON:0001987 ! placenta

[Term]
id: GO:0001892
name: embryonic placenta development
namespace: biological_process
def: "The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X]
synonym: "fetal placenta development" EXACT [GOC:dph]
is_a: GO:0048568 ! embryonic organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0007106 ! chorionic villus
relationship: part_of GO:0001701 ! in utero embryonic development
relationship: part_of GO:0001890 ! placenta development
relationship: results_in_development_of UBERON:0007106 ! chorionic villus

[Term]
id: GO:0001893
name: maternal placenta development
namespace: biological_process
def: "Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X]
synonym: "decidua development" RELATED [GOC:dph]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0048856 ! anatomical structure development
is_a: GO:0060135 ! maternal process involved in female pregnancy
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002450 ! decidua
relationship: part_of GO:0001890 ! placenta development
relationship: results_in_development_of UBERON:0002450 ! decidua

[Term]
id: GO:0001935
name: endothelial cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [GOC:add, ISBN:0781735149]
is_a: GO:0050673 ! epithelial cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000115 ! endothelial cell
relationship: acts_on_population_of CL:0000115 ! endothelial cell

[Term]
id: GO:0001936
name: regulation of endothelial cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation." [GOC:add]
is_a: GO:0050678 ! regulation of epithelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001935 ! endothelial cell proliferation
relationship: regulates GO:0001935 ! endothelial cell proliferation

[Term]
id: GO:0001937
name: negative regulation of endothelial cell proliferation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation." [GOC:add]
synonym: "down regulation of endothelial cell proliferation" EXACT []
synonym: "down-regulation of endothelial cell proliferation" EXACT []
synonym: "downregulation of endothelial cell proliferation" EXACT []
synonym: "inhibition of endothelial cell proliferation" NARROW []
is_a: GO:0001936 ! regulation of endothelial cell proliferation
is_a: GO:0050680 ! negative regulation of epithelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001935 ! endothelial cell proliferation
relationship: negatively_regulates GO:0001935 ! endothelial cell proliferation

[Term]
id: GO:0001938
name: positive regulation of endothelial cell proliferation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of endothelial cell proliferation." [GOC:add]
synonym: "activation of endothelial cell proliferation" NARROW []
synonym: "stimulation of endothelial cell proliferation" NARROW []
synonym: "up regulation of endothelial cell proliferation" EXACT []
synonym: "up-regulation of endothelial cell proliferation" EXACT []
synonym: "upregulation of endothelial cell proliferation" EXACT []
is_a: GO:0001936 ! regulation of endothelial cell proliferation
is_a: GO:0050679 ! positive regulation of epithelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001935 ! endothelial cell proliferation
relationship: positively_regulates GO:0001935 ! endothelial cell proliferation

[Term]
id: GO:0001940
name: male pronucleus
namespace: cellular_component
def: "The pronucleus originating from the spermatozoa that was involved in fertilization." [GOC:hjd, ISBN:0198506732]
is_a: GO:0045120 ! pronucleus

[Term]
id: GO:0001944
name: vasculature development
namespace: biological_process
def: "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism." [GOC:dph, UBERON:0002409]
synonym: "vascular system development" RELATED []
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002049 ! vasculature
relationship: part_of GO:0072359 ! circulatory system development
relationship: results_in_development_of UBERON:0002049 ! vasculature

[Term]
id: GO:0001955
name: blood vessel maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state." [GOC:dph]
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0001981 ! blood vessel
relationship: part_of GO:0001568 ! blood vessel development
relationship: results_in_maturation_of UBERON:0001981 ! blood vessel

[Term]
id: GO:0001956
name: positive regulation of neurotransmitter secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:hjd]
synonym: "activation of neurotransmitter secretion" NARROW []
synonym: "stimulation of neurotransmitter secretion" NARROW []
synonym: "up regulation of neurotransmitter secretion" EXACT []
synonym: "up-regulation of neurotransmitter secretion" EXACT []
synonym: "upregulation of neurotransmitter secretion" EXACT []
is_a: GO:0046928 ! regulation of neurotransmitter secretion
is_a: GO:0050806 ! positive regulation of synaptic transmission
is_a: GO:0051590 ! positive regulation of neurotransmitter transport
is_a: GO:1903532 ! positive regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007269 ! neurotransmitter secretion
relationship: positively_regulates GO:0007269 ! neurotransmitter secretion

[Term]
id: GO:0001957
name: intramembranous ossification
namespace: biological_process
def: "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells." [ISBN:0878932437]
comment: An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.
synonym: "dermal ossification" NARROW [GO_REF:0000034]
synonym: "intramembranous bone ossification" RELATED [GOC:cjm]
xref: Wikipedia:Intramembranous_ossification
is_a: GO:0036072 ! direct ossification

[Term]
id: GO:0002009
name: morphogenesis of an epithelium
namespace: biological_process
def: "The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube." [GOC:dph, GOC:jl, GOC:tb, ISBN:0198506732]
synonym: "epithelium morphogenesis" EXACT []
is_a: GO:0048729 ! tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000483 ! epithelium
relationship: part_of GO:0060429 ! epithelium development
relationship: results_in_morphogenesis_of UBERON:0000483 ! epithelium

[Term]
id: GO:0002011
name: morphogenesis of an epithelial sheet
namespace: biological_process
def: "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells." [GOC:jl]
is_a: GO:0002009 ! morphogenesis of an epithelium
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0010136 ! epithelial sheet
relationship: results_in_morphogenesis_of UBERON:0010136 ! epithelial sheet

[Term]
id: GO:0002027
name: regulation of heart rate
namespace: biological_process
def: "Any process that modulates the frequency or rate of heart contraction." [GOC:dph, GOC:tb, PMID:10358008]
synonym: "cardiac chronotropy" EXACT [GOC:dph, GOC:tb]
synonym: "regulation of heart contraction rate" EXACT []
synonym: "regulation of rate of heart contraction" EXACT []
is_a: GO:0008016 ! regulation of heart contraction

[Term]
id: GO:0002028
name: regulation of sodium ion transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph]
synonym: "regulation of Na+ transport" EXACT []
synonym: "regulation of sodium transport" EXACT []
is_a: GO:0010959 ! regulation of metal ion transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006814 ! sodium ion transport
relationship: regulates GO:0006814 ! sodium ion transport

[Term]
id: GO:0002052
name: positive regulation of neuroblast proliferation
namespace: biological_process
def: "Any process that activates or increases the rate of neuroblast proliferation." [GOC:dph]
synonym: "activation of neuroblast proliferation" NARROW []
synonym: "stimulation of neuroblast proliferation" NARROW []
synonym: "up regulation of neuroblast proliferation" EXACT []
synonym: "up-regulation of neuroblast proliferation" EXACT []
synonym: "upregulation of neuroblast proliferation" EXACT []
is_a: GO:0050769 ! positive regulation of neurogenesis
is_a: GO:1902692 ! regulation of neuroblast proliferation
is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007405 ! neuroblast proliferation
relationship: positively_regulates GO:0007405 ! neuroblast proliferation

[Term]
id: GO:0002053
name: positive regulation of mesenchymal cell proliferation
namespace: biological_process
def: "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells." [GOC:dph]
synonym: "activation of mesenchymal cell proliferation" NARROW []
synonym: "stimulation of mesenchymal cell proliferation" NARROW []
synonym: "up regulation of mesenchymal cell proliferation" EXACT []
synonym: "up-regulation of mesenchymal cell proliferation" EXACT []
synonym: "upregulation of mesenchymal cell proliferation" EXACT []
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0010464 ! regulation of mesenchymal cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010463 ! mesenchymal cell proliferation
relationship: positively_regulates GO:0010463 ! mesenchymal cell proliferation

[Term]
id: GO:0002062
name: chondrocyte differentiation
namespace: biological_process
def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:dph]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000138 ! chondrocyte
relationship: part_of GO:0051216 ! cartilage development
relationship: results_in_acquisition_of_features_of CL:0000138 ! chondrocyte

[Term]
id: GO:0002063
name: chondrocyte development
namespace: biological_process
def: "The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:dph]
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000138 ! chondrocyte
relationship: part_of GO:0002062 ! chondrocyte differentiation
relationship: results_in_development_of CL:0000138 ! chondrocyte

[Term]
id: GO:0002064
name: epithelial cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph]
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000066 ! epithelial cell
relationship: part_of GO:0030855 ! epithelial cell differentiation
relationship: results_in_development_of CL:0000066 ! epithelial cell

[Term]
id: GO:0002065
name: columnar/cuboidal epithelial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph]
is_a: GO:0030855 ! epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000075 ! columnar/cuboidal epithelial cell
relationship: results_in_acquisition_of_features_of CL:0000075 ! columnar/cuboidal epithelial cell

[Term]
id: GO:0002066
name: columnar/cuboidal epithelial cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph]
is_a: GO:0002064 ! epithelial cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000075 ! columnar/cuboidal epithelial cell
relationship: part_of GO:0002065 ! columnar/cuboidal epithelial cell differentiation
relationship: results_in_development_of CL:0000075 ! columnar/cuboidal epithelial cell

[Term]
id: GO:0002067
name: glandular epithelial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph]
is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000150 ! glandular epithelial cell
relationship: results_in_acquisition_of_features_of CL:0000150 ! glandular epithelial cell

[Term]
id: GO:0002068
name: glandular epithelial cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph]
is_a: GO:0002066 ! columnar/cuboidal epithelial cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000150 ! glandular epithelial cell
relationship: part_of GO:0002067 ! glandular epithelial cell differentiation
relationship: results_in_development_of CL:0000150 ! glandular epithelial cell

[Term]
id: GO:0002069
name: columnar/cuboidal epithelial cell maturation
namespace: biological_process
def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph]
is_a: GO:0002070 ! epithelial cell maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000075 ! columnar/cuboidal epithelial cell
relationship: part_of GO:0002066 ! columnar/cuboidal epithelial cell development
relationship: results_in_maturation_of CL:0000075 ! columnar/cuboidal epithelial cell

[Term]
id: GO:0002070
name: epithelial cell maturation
namespace: biological_process
def: "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph]
is_a: GO:0048469 ! cell maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000066 ! epithelial cell
relationship: part_of GO:0002064 ! epithelial cell development
relationship: results_in_maturation_of CL:0000066 ! epithelial cell

[Term]
id: GO:0002071
name: glandular epithelial cell maturation
namespace: biological_process
def: "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph]
is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000150 ! glandular epithelial cell
relationship: part_of GO:0002068 ! glandular epithelial cell development
relationship: results_in_maturation_of CL:0000150 ! glandular epithelial cell

[Term]
id: GO:0002072
name: optic cup morphogenesis involved in camera-type eye development
namespace: biological_process
def: "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb, ISBN:0878932437]
synonym: "optic cup morphogenesis involved in camera-style eye development" EXACT []
is_a: GO:0016331 ! morphogenesis of embryonic epithelium
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003072 ! optic cup
relationship: part_of GO:0060900 ! embryonic camera-type eye formation
relationship: results_in_morphogenesis_of UBERON:0003072 ! optic cup

[Term]
id: GO:0002080
name: acrosomal membrane
namespace: cellular_component
def: "The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization." [GOC:dph]
is_a: GO:0030667 ! secretory granule membrane
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0001669 ! acrosomal vesicle
relationship: bounding_layer_of GO:0001669 ! acrosomal vesicle
relationship: part_of GO:0001669 ! acrosomal vesicle

[Term]
id: GO:0002085
name: inhibition of neuroepithelial cell differentiation
namespace: biological_process
def: "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, PMID:16678814]
synonym: "negative regulation of neural plate formation" NARROW [GOC:dph, GOC:tb]
synonym: "repression of premature neural plate formation" NARROW [GOC:dph, GOC:tb]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
is_a: GO:0030857 ! negative regulation of epithelial cell differentiation
is_a: GO:0045995 ! regulation of embryonic development
is_a: GO:0048505 ! regulation of timing of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060563 ! neuroepithelial cell differentiation
relationship: negatively_regulates GO:0060563 ! neuroepithelial cell differentiation

[Term]
id: GO:0002087
name: regulation of respiratory gaseous exchange by nervous system process
namespace: biological_process
def: "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates." [GOC:dph, GOC:tb, PMID:12458206]
synonym: "neurological control of breathing" EXACT [GOC:dph, GOC:tb]
synonym: "regulation of respiratory gaseous exchange by neurological system process" EXACT []
is_a: GO:0044065 ! regulation of respiratory system process
is_a: GO:0050877 ! nervous system process
intersection_of: GO:0050877 ! nervous system process
intersection_of: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system

[Term]
id: GO:0002088
name: lens development in camera-type eye
namespace: biological_process
def: "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, ISBN:0582064333]
synonym: "lens development" EXACT []
synonym: "lens development in camera-style eye" EXACT []
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000965 ! lens of camera-type eye
relationship: part_of GO:0043010 ! camera-type eye development
relationship: results_in_development_of UBERON:0000965 ! lens of camera-type eye

[Term]
id: GO:0002089
name: lens morphogenesis in camera-type eye
namespace: biological_process
def: "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu]
synonym: "lens morphogenesis" EXACT []
synonym: "lens morphogenesis in camera-style eye" EXACT []
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000965 ! lens of camera-type eye
relationship: part_of GO:0002088 ! lens development in camera-type eye
relationship: part_of GO:0048593 ! camera-type eye morphogenesis
relationship: results_in_morphogenesis_of UBERON:0000965 ! lens of camera-type eye

[Term]
id: GO:0002119
name: nematode larval development
namespace: biological_process
def: "The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:ems, GOC:kmv]
is_a: GO:0002164 ! larval development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0009850 ! nematode larva
relationship: in_taxon NCBITaxon:33213 {all_only="true"} ! Bilateria
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
relationship: results_in_development_of UBERON:0009850 ! nematode larva

[Term]
id: GO:0002164
name: larval development
namespace: biological_process
def: "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." [GOC:jid, ISBN:0877795088]
is_a: GO:0007275 ! multicellular organism development
is_a: GO:0009791 ! post-embryonic development

[Term]
id: GO:0002176
name: male germ cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population." [GOC:hjd]
is_a: GO:0036093 ! germ cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000015 ! male germ cell
relationship: acts_on_population_of CL:0000015 ! male germ cell
created_by: hjd
creation_date: 2010-11-18T02:35:14Z

[Term]
id: GO:0002213
name: defense response to insect
namespace: biological_process
alt_id: GO:0002214
def: "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism." [GOC:add]
synonym: "physiological defense response to insect" EXACT []
is_a: GO:0006952 ! defense response
intersection_of: GO:0006952 ! defense response
intersection_of: has_primary_input NCBITaxon:50557 ! Insecta
relationship: has_primary_input NCBITaxon:50557 ! Insecta

[Term]
id: GO:0002215
name: defense response to nematode
namespace: biological_process
alt_id: GO:0002216
def: "A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:add, PMID:11516579, PMID:14506883]
synonym: "physiological defense response to nematode" EXACT []
is_a: GO:0006952 ! defense response
intersection_of: GO:0006952 ! defense response
intersection_of: has_primary_input NCBITaxon:6231 ! Nematoda
relationship: has_primary_input NCBITaxon:6231 ! Nematoda

[Term]
id: GO:0002244
name: hematopoietic progenitor cell differentiation
namespace: biological_process
def: "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells." [GOC:add, GOC:rl, ISBN:0781735149, PMID:16551251]
synonym: "haematopoietic progenitor cell differentiation" EXACT []
synonym: "haemopoietic progenitor cell differentiation" EXACT []
synonym: "hemopoietic progenitor cell differentiation" EXACT []
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0008001 ! hematopoietic precursor cell
relationship: part_of GO:0030097 ! hemopoiesis
relationship: results_in_acquisition_of_features_of CL:0008001 ! hematopoietic precursor cell

[Term]
id: GO:0002250
name: adaptive immune response
namespace: biological_process
def: "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." [GO_REF:0000022, GOC:add, ISBN:0781735149]
synonym: "acquired immune response" EXACT [ISBN:068340007X]
synonym: "immune memory response" EXACT [GOC:add]
xref: Wikipedia:Adaptive_immune_system
is_a: GO:0006955 ! immune response
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa

[Term]
id: GO:0002251
name: organ or tissue specific immune response
namespace: biological_process
def: "An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues." [GO_REF:0000022, GOC:jal]
synonym: "immune response in organ or tissue" EXACT []
is_a: GO:0006955 ! immune response

[Term]
id: GO:0002252
name: immune effector process
namespace: biological_process
def: "Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation." [GO_REF:0000022, GOC:add, ISBN:0781735149]
is_a: GO:0002376 ! immune system process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18737" xsd:anyURI

[Term]
id: GO:0002260
name: lymphocyte homeostasis
namespace: biological_process
def: "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, PMID:15826826, PMID:16319493, PMID:16551252, PMID:16551262]
is_a: GO:0001776 ! leukocyte homeostasis
intersection_of: GO:0048872 ! homeostasis of number of cells
intersection_of: acts_on_population_of CL:0000542 ! lymphocyte
relationship: acts_on_population_of CL:0000542 ! lymphocyte

[Term]
id: GO:0002262
name: myeloid cell homeostasis
namespace: biological_process
def: "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000763, GOC:add]
is_a: GO:0002376 ! immune system process
is_a: GO:0048872 ! homeostasis of number of cells
intersection_of: GO:0048872 ! homeostasis of number of cells
intersection_of: acts_on_population_of CL:0000763 ! myeloid cell
relationship: acts_on_population_of CL:0000763 ! myeloid cell

[Term]
id: GO:0002263
name: cell activation involved in immune response
namespace: biological_process
def: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GO_REF:0000022, GOC:add, ISBN:0781735149]
synonym: "cell activation during immune response" RELATED [GOC:tb]
is_a: GO:0001775 ! cell activation
is_a: GO:0002252 ! immune effector process
intersection_of: GO:0001775 ! cell activation
intersection_of: part_of GO:0006955 ! immune response
relationship: part_of GO:0006955 ! immune response

[Term]
id: GO:0002264
name: endothelial cell activation involved in immune response
namespace: biological_process
def: "A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149]
synonym: "endothelial cell activation during immune response" RELATED [GOC:tb]
is_a: GO:0002263 ! cell activation involved in immune response
is_a: GO:0042118 ! endothelial cell activation
intersection_of: GO:0042118 ! endothelial cell activation
intersection_of: part_of GO:0006955 ! immune response

[Term]
id: GO:0002269
name: leukocyte activation involved in inflammatory response
namespace: biological_process
def: "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response." [GOC:add, ISBN:0781735149]
synonym: "immune cell activation during inflammatory response" RELATED []
synonym: "leukocyte activation during inflammatory response" RELATED [GOC:tb]
is_a: GO:0045321 ! leukocyte activation
intersection_of: GO:0045321 ! leukocyte activation
intersection_of: part_of GO:0006954 ! inflammatory response
relationship: part_of GO:0006954 ! inflammatory response

[Term]
id: GO:0002274
name: myeloid leukocyte activation
namespace: biological_process
def: "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:add, ISBN:0781735149]
synonym: "myeloid leucocyte activation" EXACT []
is_a: GO:0045321 ! leukocyte activation
intersection_of: GO:0001775 ! cell activation
intersection_of: has_primary_input CL:0000766 ! myeloid leukocyte
relationship: has_primary_input CL:0000766 ! myeloid leukocyte

[Term]
id: GO:0002285
name: lymphocyte activation involved in immune response
namespace: biological_process
def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149]
synonym: "lymphocyte activation during immune response" RELATED [GOC:tb]
is_a: GO:0002366 ! leukocyte activation involved in immune response
is_a: GO:0046649 ! lymphocyte activation
intersection_of: GO:0046649 ! lymphocyte activation
intersection_of: part_of GO:0006955 ! immune response

[Term]
id: GO:0002286
name: T cell activation involved in immune response
namespace: biological_process
def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149]
synonym: "T cell activation during immune response" RELATED [GOC:tb]
synonym: "T lymphocyte activation during immune response" RELATED []
synonym: "T-cell activation during immune response" RELATED []
synonym: "T-lymphocyte activation during immune response" RELATED []
is_a: GO:0002285 ! lymphocyte activation involved in immune response
is_a: GO:0042110 ! T cell activation
intersection_of: GO:0042110 ! T cell activation
intersection_of: part_of GO:0006955 ! immune response

[Term]
id: GO:0002292
name: T cell differentiation involved in immune response
namespace: biological_process
def: "The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add, ISBN:0781735149]
comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
synonym: "T cell development involved in immune response" RELATED [GOC:add]
synonym: "T cell differentiation during immune response" RELATED [GOC:tb]
synonym: "T lymphocyte differentiation during immune response" RELATED []
synonym: "T-cell differentiation during immune response" RELATED []
synonym: "T-lymphocyte differentiation during immune response" RELATED []
is_a: GO:0002286 ! T cell activation involved in immune response
is_a: GO:0030217 ! T cell differentiation
intersection_of: GO:0030217 ! T cell differentiation
intersection_of: part_of GO:0006955 ! immune response

[Term]
id: GO:0002309
name: T cell proliferation involved in immune response
namespace: biological_process
def: "The expansion of a T cell population by cell division as part of an immune response." [GOC:add, ISBN:0781735149]
synonym: "T cell proliferation during immune response" RELATED [GOC:tb]
synonym: "T lymphocyte proliferation during immune response" RELATED []
synonym: "T-cell proliferation during immune response" RELATED []
synonym: "T-lymphocyte proliferation during immune response" RELATED []
is_a: GO:0002286 ! T cell activation involved in immune response
is_a: GO:0042098 ! T cell proliferation
intersection_of: GO:0042098 ! T cell proliferation
intersection_of: part_of GO:0006955 ! immune response

[Term]
id: GO:0002318
name: myeloid progenitor cell differentiation
namespace: biological_process
def: "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages." [GOC:add, PMID:16551264]
is_a: GO:0002244 ! hematopoietic progenitor cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000839 ! myeloid lineage restricted progenitor cell
relationship: results_in_acquisition_of_features_of CL:0000839 ! myeloid lineage restricted progenitor cell

[Term]
id: GO:0002320
name: lymphoid progenitor cell differentiation
namespace: biological_process
def: "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages." [GOC:add, PMID:16551251, PMID:16551264]
is_a: GO:0002244 ! hematopoietic progenitor cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000838 ! lymphoid lineage restricted progenitor cell
relationship: results_in_acquisition_of_features_of CL:0000838 ! lymphoid lineage restricted progenitor cell

[Term]
id: GO:0002351
name: serotonin production involved in inflammatory response
namespace: biological_process
def: "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:16730260]
synonym: "serotonin production involved in acute inflammatory response" BROAD []
is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response

[Term]
id: GO:0002366
name: leukocyte activation involved in immune response
namespace: biological_process
def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149]
synonym: "immune cell activation during immune response" RELATED []
synonym: "leucocyte activation during immune response" RELATED []
synonym: "leukocyte activation during immune response" RELATED [GOC:tb]
is_a: GO:0002263 ! cell activation involved in immune response
is_a: GO:0045321 ! leukocyte activation
intersection_of: GO:0045321 ! leukocyte activation
intersection_of: part_of GO:0006955 ! immune response

[Term]
id: GO:0002367
name: cytokine production involved in immune response
namespace: biological_process
alt_id: GO:0002374
alt_id: GO:0002375
def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
subset: gocheck_do_not_annotate
synonym: "cytokine biosynthetic process involved in immune response" NARROW []
synonym: "cytokine production during immune response" RELATED [GOC:dph]
synonym: "cytokine secretion during immune response" RELATED [GOC:dph]
synonym: "cytokine secretion involved in immune response" RELATED []
is_a: GO:0001816 ! cytokine production
is_a: GO:0002440 ! production of molecular mediator of immune response
intersection_of: GO:0001816 ! cytokine production
intersection_of: part_of GO:0006955 ! immune response
relationship: part_of GO:0006955 ! immune response

[Term]
id: GO:0002369
name: T cell cytokine production
namespace: biological_process
def: "Any process that contributes to cytokine production by a T cell." [GOC:add, ISBN:0781735149]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
subset: gocheck_do_not_annotate
synonym: "T lymphocyte cytokine production" EXACT []
synonym: "T-cell cytokine production" EXACT []
synonym: "T-lymphocyte cytokine production" EXACT []
is_a: GO:0002367 ! cytokine production involved in immune response
is_a: GO:0002456 ! T cell mediated immunity
intersection_of: GO:0001816 ! cytokine production
intersection_of: process_has_causal_agent CL:0000084 ! T cell

[Term]
id: GO:0002371
name: dendritic cell cytokine production
namespace: biological_process
def: "Any process that contributes to cytokine production by a dendritic cell." [GOC:add, ISBN:0781735149]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
subset: gocheck_do_not_annotate
is_a: GO:0002367 ! cytokine production involved in immune response
is_a: GO:0002443 ! leukocyte mediated immunity
intersection_of: GO:0001816 ! cytokine production
intersection_of: process_has_causal_agent CL:0000451 ! dendritic cell
relationship: process_has_causal_agent CL:0000451 ! dendritic cell

[Term]
id: GO:0002376
name: immune system process
namespace: biological_process
def: "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." [GO_REF:0000022, GOC:add]
comment: Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501).
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_mouse
subset: goslim_pir
xref: Wikipedia:Immune_system
is_a: GO:0008150 ! biological process
property_value: RO:0002161 NCBITaxon:4895

[Term]
id: GO:0002384
name: hepatic immune response
namespace: biological_process
def: "An immune response taking place in the liver." [GO_REF:0000022, GOC:jal, ISBN:0781735149]
is_a: GO:0002251 ! organ or tissue specific immune response
intersection_of: GO:0006955 ! immune response
intersection_of: occurs_in UBERON:0002107 ! liver
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: occurs_in UBERON:0002107 ! liver
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>

[Term]
id: GO:0002396
name: MHC protein complex assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678]
is_a: GO:0065003 ! protein-containing complex assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0042611 ! MHC protein complex
relationship: results_in_assembly_of GO:0042611 ! MHC protein complex

[Term]
id: GO:0002399
name: MHC class II protein complex assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15771591]
is_a: GO:0002396 ! MHC protein complex assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0042613 ! MHC class II protein complex
relationship: results_in_assembly_of GO:0042613 ! MHC class II protein complex

[Term]
id: GO:0002440
name: production of molecular mediator of immune response
namespace: biological_process
def: "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
subset: gocheck_do_not_annotate
synonym: "production of cellular mediator of immune response" RELATED []
is_a: GO:0002376 ! immune system process
is_a: GO:0010467 ! gene expression

[Term]
id: GO:0002442
name: serotonin secretion involved in inflammatory response
namespace: biological_process
def: "The regulated release of serotonin by a cell as part of an inflammatory response." [GOC:add, ISBN:0781735149]
synonym: "serotonin release involved in inflammatory response" RELATED [GOC:tb]
synonym: "serotonin secretion involved in acute inflammatory response" BROAD []
is_a: GO:0001820 ! serotonin secretion
intersection_of: GO:0001820 ! serotonin secretion
intersection_of: part_of GO:0006954 ! inflammatory response
relationship: part_of GO:0002351 ! serotonin production involved in inflammatory response

[Term]
id: GO:0002443
name: leukocyte mediated immunity
namespace: biological_process
alt_id: GO:0019723
alt_id: GO:0042087
def: "Any process involved in the carrying out of an immune response by a leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149]
synonym: "cell-mediated immune response" RELATED []
synonym: "cellular immune response" RELATED []
synonym: "immune cell effector process" EXACT []
synonym: "immune cell mediated immunity" EXACT []
synonym: "leucocyte immune effector process" EXACT []
synonym: "leucocyte mediated immunity" EXACT []
synonym: "leukocyte immune effector process" EXACT []
is_a: GO:0002252 ! immune effector process
intersection_of: GO:0002376 ! immune system process
intersection_of: process_has_causal_agent CL:0000738 ! leukocyte
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: process_has_causal_agent CL:0000738 ! leukocyte

[Term]
id: GO:0002444
name: myeloid leukocyte mediated immunity
namespace: biological_process
def: "Any process involved in the carrying out of an immune response by a myeloid leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149]
synonym: "myeloid leucocyte immune effector process" EXACT []
synonym: "myeloid leucocyte mediated immunity" EXACT []
synonym: "myeloid leukocyte immune effector process" EXACT []
is_a: GO:0002443 ! leukocyte mediated immunity
intersection_of: GO:0002376 ! immune system process
intersection_of: process_has_causal_agent CL:0000766 ! myeloid leukocyte
relationship: process_has_causal_agent CL:0000766 ! myeloid leukocyte

[Term]
id: GO:0002449
name: lymphocyte mediated immunity
namespace: biological_process
def: "Any process involved in the carrying out of an immune response by a lymphocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149]
synonym: "cell-mediated immunity" BROAD []
synonym: "cellular immune response" BROAD []
is_a: GO:0002443 ! leukocyte mediated immunity
intersection_of: GO:0002376 ! immune system process
intersection_of: process_has_causal_agent CL:0000542 ! lymphocyte
relationship: process_has_causal_agent CL:0000542 ! lymphocyte

[Term]
id: GO:0002456
name: T cell mediated immunity
namespace: biological_process
def: "Any process involved in the carrying out of an immune response by a T cell." [GO_REF:0000022, GOC:add, ISBN:0781735149]
synonym: "cell-mediated immunity" BROAD []
synonym: "cellular immune response" BROAD []
synonym: "T lymphocyte mediated immunity" EXACT []
synonym: "T-cell mediated immunity" EXACT []
synonym: "T-lymphocyte mediated immunity" EXACT []
is_a: GO:0002449 ! lymphocyte mediated immunity
is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
intersection_of: GO:0002376 ! immune system process
intersection_of: process_has_causal_agent CL:0000084 ! T cell
relationship: process_has_causal_agent CL:0000084 ! T cell

[Term]
id: GO:0002457
name: T cell antigen processing and presentation
namespace: biological_process
def: "The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, PMID:11417857, PMID:15120183]
synonym: "T lymphocyte antigen processing and presentation" EXACT []
synonym: "T-cell antigen processing and presentation" EXACT []
synonym: "T-lymphocyte antigen processing and presentation" EXACT []
is_a: GO:0019882 ! antigen processing and presentation
intersection_of: GO:0019882 ! antigen processing and presentation
intersection_of: occurs_in CL:0000084 ! T cell
relationship: occurs_in CL:0000084 ! T cell
relationship: part_of GO:0002456 ! T cell mediated immunity

[Term]
id: GO:0002460
name: adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
namespace: biological_process
def: "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus." [GOC:add, GOC:mtg_sensu, ISBN:0781735149, ISBN:1405196831]
is_a: GO:0002250 ! adaptive immune response

[Term]
id: GO:0002468
name: dendritic cell antigen processing and presentation
namespace: biological_process
def: "The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591]
is_a: GO:0019882 ! antigen processing and presentation
intersection_of: GO:0019882 ! antigen processing and presentation
intersection_of: occurs_in CL:0000451 ! dendritic cell
relationship: occurs_in CL:0000451 ! dendritic cell

[Term]
id: GO:0002504
name: antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
namespace: biological_process
def: "The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15531770, PMID:15771591, PMID:16153240]
synonym: "peptide or polysaccharide antigen processing and presentation of via MHC class II" EXACT []
is_a: GO:0019882 ! antigen processing and presentation

[Term]
id: GO:0002520
name: immune system development
namespace: biological_process
def: "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:add, GOC:dph]
subset: goslim_drosophila
is_a: GO:0002376 ! immune system process
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002405 ! immune system
relationship: results_in_development_of UBERON:0002405 ! immune system

[Term]
id: GO:0002521
name: leukocyte differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:add, PMID:16551264]
synonym: "immune cell differentiation" EXACT []
synonym: "leucocyte differentiation" EXACT []
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000738 ! leukocyte
relationship: part_of GO:0030097 ! hemopoiesis
relationship: results_in_acquisition_of_features_of CL:0000738 ! leukocyte

[Term]
id: GO:0002522
name: leukocyte migration involved in immune response
namespace: biological_process
def: "The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538]
synonym: "immune cell migration during immune response" EXACT []
synonym: "immune cell trafficking during immune response" EXACT []
synonym: "leucocyte migration during immune response" EXACT []
synonym: "leucocyte trafficking during immune response" EXACT []
synonym: "leukocyte trafficking during immune response" EXACT []
is_a: GO:0002252 ! immune effector process
is_a: GO:0050900 ! leukocyte migration
intersection_of: GO:0050900 ! leukocyte migration
intersection_of: part_of GO:0006955 ! immune response
relationship: part_of GO:0006955 ! immune response

[Term]
id: GO:0002523
name: leukocyte migration involved in inflammatory response
namespace: biological_process
def: "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538]
synonym: "immune cell migration during inflammatory response" RELATED []
synonym: "immune cell trafficking during inflammatory response" RELATED []
synonym: "leucocyte migration during inflammatory response" RELATED []
synonym: "leucocyte trafficking during inflammatory response" RELATED []
synonym: "leukocyte migration during inflammatory response" RELATED [GOC:dph]
synonym: "leukocyte trafficking during inflammatory response" RELATED []
is_a: GO:0050900 ! leukocyte migration
intersection_of: GO:0050900 ! leukocyte migration
intersection_of: part_of GO:0006954 ! inflammatory response
relationship: part_of GO:0006954 ! inflammatory response

[Term]
id: GO:0002532
name: production of molecular mediator involved in inflammatory response
namespace: biological_process
def: "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:dph, GOC:tb, ISBN:0781735149]
synonym: "production of cellular mediator of acute inflammation" RELATED []
synonym: "production of molecular mediator involved in acute inflammatory response" BROAD []
is_a: GO:0032501 ! multicellular organismal process
relationship: part_of GO:0006954 ! inflammatory response

[Term]
id: GO:0002534
name: cytokine production involved in inflammatory response
namespace: biological_process
def: "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149]
subset: gocheck_do_not_annotate
synonym: "cytokine production involved in acute inflammatory response" BROAD []
is_a: GO:0001816 ! cytokine production
is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response
intersection_of: GO:0001816 ! cytokine production
intersection_of: part_of GO:0006954 ! inflammatory response

[Term]
id: GO:0002572
name: pro-T cell differentiation
namespace: biological_process
def: "The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed." [GOC:add, ISBN:0781735149]
synonym: "pro-T lymphocyte differentiation" EXACT []
is_a: GO:0002320 ! lymphoid progenitor cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000827 ! pro-T cell
relationship: part_of GO:0030217 ! T cell differentiation
relationship: results_in_acquisition_of_features_of CL:0000827 ! pro-T cell

[Term]
id: GO:0002573
name: myeloid leukocyte differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage." [GOC:add, PMID:16551251]
synonym: "myeloid leucocyte differentiation" EXACT []
is_a: GO:0002521 ! leukocyte differentiation
is_a: GO:0030099 ! myeloid cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000766 ! myeloid leukocyte
relationship: results_in_acquisition_of_features_of CL:0000766 ! myeloid leukocyte

[Term]
id: GO:0002577
name: regulation of antigen processing and presentation
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation." [GOC:add]
is_a: GO:0002682 ! regulation of immune system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0019882 ! antigen processing and presentation
relationship: regulates GO:0019882 ! antigen processing and presentation

[Term]
id: GO:0002578
name: negative regulation of antigen processing and presentation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation." [GOC:add]
synonym: "down regulation of antigen processing and presentation" EXACT []
synonym: "down-regulation of antigen processing and presentation" EXACT []
synonym: "downregulation of antigen processing and presentation" EXACT []
synonym: "inhibition of antigen processing and presentation" NARROW []
is_a: GO:0002577 ! regulation of antigen processing and presentation
is_a: GO:0002683 ! negative regulation of immune system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0019882 ! antigen processing and presentation
relationship: negatively_regulates GO:0019882 ! antigen processing and presentation

[Term]
id: GO:0002579
name: positive regulation of antigen processing and presentation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation." [GOC:add]
synonym: "activation of antigen processing and presentation" NARROW []
synonym: "stimulation of antigen processing and presentation" NARROW []
synonym: "up regulation of antigen processing and presentation" EXACT []
synonym: "up-regulation of antigen processing and presentation" EXACT []
synonym: "upregulation of antigen processing and presentation" EXACT []
is_a: GO:0002577 ! regulation of antigen processing and presentation
is_a: GO:0002684 ! positive regulation of immune system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0019882 ! antigen processing and presentation
relationship: positively_regulates GO:0019882 ! antigen processing and presentation

[Term]
id: GO:0002580
name: regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add]
synonym: "regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT []
is_a: GO:0002577 ! regulation of antigen processing and presentation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
relationship: regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

[Term]
id: GO:0002581
name: negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add]
synonym: "down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT []
synonym: "down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT []
synonym: "downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT []
synonym: "inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW []
synonym: "negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT []
is_a: GO:0002578 ! negative regulation of antigen processing and presentation
is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
relationship: negatively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

[Term]
id: GO:0002582
name: positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add]
synonym: "activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW []
synonym: "positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT []
synonym: "stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW []
synonym: "up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT []
synonym: "up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT []
synonym: "upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT []
is_a: GO:0002579 ! positive regulation of antigen processing and presentation
is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
relationship: positively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

[Term]
id: GO:0002604
name: regulation of dendritic cell antigen processing and presentation
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add]
is_a: GO:0002577 ! regulation of antigen processing and presentation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002468 ! dendritic cell antigen processing and presentation
relationship: regulates GO:0002468 ! dendritic cell antigen processing and presentation

[Term]
id: GO:0002605
name: negative regulation of dendritic cell antigen processing and presentation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add]
synonym: "down regulation of dendritic cell antigen processing and presentation" EXACT []
synonym: "down-regulation of dendritic cell antigen processing and presentation" EXACT []
synonym: "downregulation of dendritic cell antigen processing and presentation" EXACT []
synonym: "inhibition of dendritic cell antigen processing and presentation" NARROW []
is_a: GO:0002578 ! negative regulation of antigen processing and presentation
is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002468 ! dendritic cell antigen processing and presentation
relationship: negatively_regulates GO:0002468 ! dendritic cell antigen processing and presentation

[Term]
id: GO:0002606
name: positive regulation of dendritic cell antigen processing and presentation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add]
synonym: "activation of dendritic cell antigen processing and presentation" NARROW []
synonym: "stimulation of dendritic cell antigen processing and presentation" NARROW []
synonym: "up regulation of dendritic cell antigen processing and presentation" EXACT []
synonym: "up-regulation of dendritic cell antigen processing and presentation" EXACT []
synonym: "upregulation of dendritic cell antigen processing and presentation" EXACT []
is_a: GO:0002579 ! positive regulation of antigen processing and presentation
is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002468 ! dendritic cell antigen processing and presentation
relationship: positively_regulates GO:0002468 ! dendritic cell antigen processing and presentation

[Term]
id: GO:0002625
name: regulation of T cell antigen processing and presentation
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add]
synonym: "regulation of T lymphocyte antigen processing and presentation" EXACT []
synonym: "regulation of T-cell antigen processing and presentation" EXACT []
synonym: "regulation of T-lymphocyte antigen processing and presentation" EXACT []
is_a: GO:0002577 ! regulation of antigen processing and presentation
is_a: GO:0002709 ! regulation of T cell mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002457 ! T cell antigen processing and presentation
relationship: regulates GO:0002457 ! T cell antigen processing and presentation

[Term]
id: GO:0002626
name: negative regulation of T cell antigen processing and presentation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add]
synonym: "down regulation of T cell antigen processing and presentation" EXACT []
synonym: "down-regulation of T cell antigen processing and presentation" EXACT []
synonym: "downregulation of T cell antigen processing and presentation" EXACT []
synonym: "inhibition of T cell antigen processing and presentation" NARROW []
synonym: "negative regulation of T lymphocyte antigen processing and presentation" EXACT []
synonym: "negative regulation of T-cell antigen processing and presentation" EXACT []
synonym: "negative regulation of T-lymphocyte antigen processing and presentation" EXACT []
is_a: GO:0002578 ! negative regulation of antigen processing and presentation
is_a: GO:0002625 ! regulation of T cell antigen processing and presentation
is_a: GO:0002710 ! negative regulation of T cell mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002457 ! T cell antigen processing and presentation
relationship: negatively_regulates GO:0002457 ! T cell antigen processing and presentation

[Term]
id: GO:0002627
name: positive regulation of T cell antigen processing and presentation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add]
synonym: "activation of T cell antigen processing and presentation" NARROW []
synonym: "positive regulation of T lymphocyte antigen processing and presentation" EXACT []
synonym: "positive regulation of T-cell antigen processing and presentation" EXACT []
synonym: "positive regulation of T-lymphocyte antigen processing and presentation" EXACT []
synonym: "stimulation of T cell antigen processing and presentation" NARROW []
synonym: "up regulation of T cell antigen processing and presentation" EXACT []
synonym: "up-regulation of T cell antigen processing and presentation" EXACT []
synonym: "upregulation of T cell antigen processing and presentation" EXACT []
is_a: GO:0002579 ! positive regulation of antigen processing and presentation
is_a: GO:0002625 ! regulation of T cell antigen processing and presentation
is_a: GO:0002711 ! positive regulation of T cell mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002457 ! T cell antigen processing and presentation
relationship: positively_regulates GO:0002457 ! T cell antigen processing and presentation

[Term]
id: GO:0002682
name: regulation of immune system process
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of an immune system process." [GOC:add]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002376 ! immune system process
relationship: regulates GO:0002376 ! immune system process

[Term]
id: GO:0002683
name: negative regulation of immune system process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process." [GOC:add]
synonym: "down regulation of immune system process" EXACT []
synonym: "down-regulation of immune system process" EXACT []
synonym: "downregulation of immune system process" EXACT []
synonym: "inhibition of immune system process" NARROW []
is_a: GO:0002682 ! regulation of immune system process
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002376 ! immune system process
relationship: negatively_regulates GO:0002376 ! immune system process

[Term]
id: GO:0002684
name: positive regulation of immune system process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of an immune system process." [GOC:add]
synonym: "activation of immune system process" NARROW []
synonym: "stimulation of immune system process" NARROW []
synonym: "up regulation of immune system process" EXACT []
synonym: "up-regulation of immune system process" EXACT []
synonym: "upregulation of immune system process" EXACT []
is_a: GO:0002682 ! regulation of immune system process
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002376 ! immune system process
relationship: positively_regulates GO:0002376 ! immune system process

[Term]
id: GO:0002685
name: regulation of leukocyte migration
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of leukocyte migration." [GOC:add]
synonym: "regulation of immune cell migration" EXACT []
synonym: "regulation of leucocyte migration" EXACT []
is_a: GO:0002682 ! regulation of immune system process
is_a: GO:0030334 ! regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0050900 ! leukocyte migration
relationship: regulates GO:0050900 ! leukocyte migration

[Term]
id: GO:0002686
name: negative regulation of leukocyte migration
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration." [GOC:add]
synonym: "down regulation of leukocyte migration" EXACT []
synonym: "down-regulation of leukocyte migration" EXACT []
synonym: "downregulation of leukocyte migration" EXACT []
synonym: "inhibition of leukocyte migration" NARROW []
synonym: "negative regulation of immune cell migration" EXACT []
synonym: "negative regulation of leucocyte migration" EXACT []
is_a: GO:0002683 ! negative regulation of immune system process
is_a: GO:0002685 ! regulation of leukocyte migration
is_a: GO:0030336 ! negative regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0050900 ! leukocyte migration
relationship: negatively_regulates GO:0050900 ! leukocyte migration

[Term]
id: GO:0002687
name: positive regulation of leukocyte migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of leukocyte migration." [GOC:add]
synonym: "activation of leukocyte migration" NARROW []
synonym: "positive regulation of immune cell migration" EXACT []
synonym: "positive regulation of leucocyte migration" EXACT []
synonym: "stimulation of leukocyte migration" NARROW []
synonym: "up regulation of leukocyte migration" EXACT []
synonym: "up-regulation of leukocyte migration" EXACT []
synonym: "upregulation of leukocyte migration" EXACT []
is_a: GO:0002684 ! positive regulation of immune system process
is_a: GO:0002685 ! regulation of leukocyte migration
is_a: GO:0030335 ! positive regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0050900 ! leukocyte migration
relationship: positively_regulates GO:0050900 ! leukocyte migration

[Term]
id: GO:0002694
name: regulation of leukocyte activation
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of leukocyte activation." [GOC:add]
synonym: "regulation of immune cell activation" EXACT []
synonym: "regulation of leucocyte activation" EXACT []
is_a: GO:0002682 ! regulation of immune system process
is_a: GO:0050865 ! regulation of cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0045321 ! leukocyte activation
relationship: regulates GO:0045321 ! leukocyte activation

[Term]
id: GO:0002695
name: negative regulation of leukocyte activation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation." [GOC:add]
synonym: "down regulation of leukocyte activation" EXACT []
synonym: "down-regulation of leukocyte activation" EXACT []
synonym: "downregulation of leukocyte activation" EXACT []
synonym: "inhibition of leukocyte activation" NARROW []
synonym: "negative regulation of immune cell activation" EXACT []
synonym: "negative regulation of leucocyte activation" EXACT []
is_a: GO:0002683 ! negative regulation of immune system process
is_a: GO:0002694 ! regulation of leukocyte activation
is_a: GO:0050866 ! negative regulation of cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045321 ! leukocyte activation
relationship: negatively_regulates GO:0045321 ! leukocyte activation

[Term]
id: GO:0002696
name: positive regulation of leukocyte activation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." [GOC:add]
synonym: "activation of leukocyte activation" NARROW []
synonym: "positive regulation of immune cell activation" EXACT []
synonym: "positive regulation of leucocyte activation" EXACT []
synonym: "stimulation of leukocyte activation" NARROW []
synonym: "up regulation of leukocyte activation" EXACT []
synonym: "up-regulation of leukocyte activation" EXACT []
synonym: "upregulation of leukocyte activation" EXACT []
is_a: GO:0002684 ! positive regulation of immune system process
is_a: GO:0002694 ! regulation of leukocyte activation
is_a: GO:0050867 ! positive regulation of cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0045321 ! leukocyte activation
relationship: positively_regulates GO:0045321 ! leukocyte activation

[Term]
id: GO:0002697
name: regulation of immune effector process
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of an immune effector process." [GOC:add]
is_a: GO:0002682 ! regulation of immune system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002252 ! immune effector process
relationship: regulates GO:0002252 ! immune effector process

[Term]
id: GO:0002698
name: negative regulation of immune effector process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process." [GOC:add]
synonym: "down regulation of immune effector process" EXACT []
synonym: "down-regulation of immune effector process" EXACT []
synonym: "downregulation of immune effector process" EXACT []
synonym: "inhibition of immune effector process" NARROW []
is_a: GO:0002683 ! negative regulation of immune system process
is_a: GO:0002697 ! regulation of immune effector process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002252 ! immune effector process
relationship: negatively_regulates GO:0002252 ! immune effector process

[Term]
id: GO:0002699
name: positive regulation of immune effector process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of an immune effector process." [GOC:add]
synonym: "activation of immune effector process" NARROW []
synonym: "stimulation of immune effector process" NARROW []
synonym: "up regulation of immune effector process" EXACT []
synonym: "up-regulation of immune effector process" EXACT []
synonym: "upregulation of immune effector process" EXACT []
is_a: GO:0002684 ! positive regulation of immune system process
is_a: GO:0002697 ! regulation of immune effector process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002252 ! immune effector process
relationship: positively_regulates GO:0002252 ! immune effector process

[Term]
id: GO:0002700
name: regulation of production of molecular mediator of immune response
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add]
is_a: GO:0002697 ! regulation of immune effector process
is_a: GO:0010468 ! regulation of gene expression
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002440 ! production of molecular mediator of immune response
relationship: regulates GO:0002440 ! production of molecular mediator of immune response

[Term]
id: GO:0002701
name: negative regulation of production of molecular mediator of immune response
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add]
synonym: "down regulation of production of molecular mediator of immune response" EXACT []
synonym: "down-regulation of production of molecular mediator of immune response" EXACT []
synonym: "downregulation of production of molecular mediator of immune response" EXACT []
synonym: "inhibition of production of molecular mediator of immune response" NARROW []
is_a: GO:0002698 ! negative regulation of immune effector process
is_a: GO:0002700 ! regulation of production of molecular mediator of immune response
is_a: GO:0010629 ! negative regulation of gene expression
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002440 ! production of molecular mediator of immune response
relationship: negatively_regulates GO:0002440 ! production of molecular mediator of immune response

[Term]
id: GO:0002702
name: positive regulation of production of molecular mediator of immune response
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add]
synonym: "activation of production of molecular mediator of immune response" NARROW []
synonym: "stimulation of production of molecular mediator of immune response" NARROW []
synonym: "up regulation of production of molecular mediator of immune response" EXACT []
synonym: "up-regulation of production of molecular mediator of immune response" EXACT []
synonym: "upregulation of production of molecular mediator of immune response" EXACT []
is_a: GO:0002699 ! positive regulation of immune effector process
is_a: GO:0002700 ! regulation of production of molecular mediator of immune response
is_a: GO:0010628 ! positive regulation of gene expression
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002440 ! production of molecular mediator of immune response
relationship: positively_regulates GO:0002440 ! production of molecular mediator of immune response

[Term]
id: GO:0002703
name: regulation of leukocyte mediated immunity
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add]
synonym: "regulation of immune cell mediated immunity" EXACT []
synonym: "regulation of leucocyte mediated immunity" EXACT []
is_a: GO:0002697 ! regulation of immune effector process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002443 ! leukocyte mediated immunity
relationship: regulates GO:0002443 ! leukocyte mediated immunity

[Term]
id: GO:0002704
name: negative regulation of leukocyte mediated immunity
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add]
synonym: "down regulation of leukocyte mediated immunity" EXACT []
synonym: "down-regulation of leukocyte mediated immunity" EXACT []
synonym: "downregulation of leukocyte mediated immunity" EXACT []
synonym: "inhibition of leukocyte mediated immunity" NARROW []
synonym: "negative regulation of immune cell mediated immunity" EXACT []
synonym: "negative regulation of leucocyte mediated immunity" EXACT []
is_a: GO:0002698 ! negative regulation of immune effector process
is_a: GO:0002703 ! regulation of leukocyte mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002443 ! leukocyte mediated immunity
relationship: negatively_regulates GO:0002443 ! leukocyte mediated immunity

[Term]
id: GO:0002705
name: positive regulation of leukocyte mediated immunity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add]
synonym: "activation of leukocyte mediated immunity" NARROW []
synonym: "positive regulation of immune cell mediated immunity" EXACT []
synonym: "positive regulation of leucocyte mediated immunity" EXACT []
synonym: "stimulation of leukocyte mediated immunity" NARROW []
synonym: "up regulation of leukocyte mediated immunity" EXACT []
synonym: "up-regulation of leukocyte mediated immunity" EXACT []
synonym: "upregulation of leukocyte mediated immunity" EXACT []
is_a: GO:0002699 ! positive regulation of immune effector process
is_a: GO:0002703 ! regulation of leukocyte mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002443 ! leukocyte mediated immunity
relationship: positively_regulates GO:0002443 ! leukocyte mediated immunity

[Term]
id: GO:0002706
name: regulation of lymphocyte mediated immunity
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add]
is_a: GO:0002703 ! regulation of leukocyte mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002449 ! lymphocyte mediated immunity
relationship: regulates GO:0002449 ! lymphocyte mediated immunity

[Term]
id: GO:0002707
name: negative regulation of lymphocyte mediated immunity
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add]
synonym: "down regulation of lymphocyte mediated immunity" EXACT []
synonym: "down-regulation of lymphocyte mediated immunity" EXACT []
synonym: "downregulation of lymphocyte mediated immunity" EXACT []
synonym: "inhibition of lymphocyte mediated immunity" NARROW []
is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity
is_a: GO:0002706 ! regulation of lymphocyte mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002449 ! lymphocyte mediated immunity
relationship: negatively_regulates GO:0002449 ! lymphocyte mediated immunity

[Term]
id: GO:0002708
name: positive regulation of lymphocyte mediated immunity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add]
synonym: "activation of lymphocyte mediated immunity" NARROW []
synonym: "stimulation of lymphocyte mediated immunity" NARROW []
synonym: "up regulation of lymphocyte mediated immunity" EXACT []
synonym: "up-regulation of lymphocyte mediated immunity" EXACT []
synonym: "upregulation of lymphocyte mediated immunity" EXACT []
is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity
is_a: GO:0002706 ! regulation of lymphocyte mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002449 ! lymphocyte mediated immunity
relationship: positively_regulates GO:0002449 ! lymphocyte mediated immunity

[Term]
id: GO:0002709
name: regulation of T cell mediated immunity
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of T cell mediated immunity." [GOC:add]
synonym: "regulation of T lymphocyte mediated immunity" EXACT []
synonym: "regulation of T-cell mediated immunity" EXACT []
synonym: "regulation of T-lymphocyte mediated immunity" EXACT []
is_a: GO:0002706 ! regulation of lymphocyte mediated immunity
is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002456 ! T cell mediated immunity
relationship: regulates GO:0002456 ! T cell mediated immunity

[Term]
id: GO:0002710
name: negative regulation of T cell mediated immunity
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity." [GOC:add]
synonym: "down regulation of T cell mediated immunity" EXACT []
synonym: "down-regulation of T cell mediated immunity" EXACT []
synonym: "downregulation of T cell mediated immunity" EXACT []
synonym: "inhibition of T cell mediated immunity" NARROW []
synonym: "negative regulation of T lymphocyte mediated immunity" EXACT []
synonym: "negative regulation of T-cell mediated immunity" EXACT []
synonym: "negative regulation of T-lymphocyte mediated immunity" EXACT []
is_a: GO:0002707 ! negative regulation of lymphocyte mediated immunity
is_a: GO:0002709 ! regulation of T cell mediated immunity
is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002456 ! T cell mediated immunity
relationship: negatively_regulates GO:0002456 ! T cell mediated immunity

[Term]
id: GO:0002711
name: positive regulation of T cell mediated immunity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity." [GOC:add]
synonym: "activation of T cell mediated immunity" NARROW []
synonym: "positive regulation of T lymphocyte mediated immunity" EXACT []
synonym: "positive regulation of T-cell mediated immunity" EXACT []
synonym: "positive regulation of T-lymphocyte mediated immunity" EXACT []
synonym: "stimulation of T cell mediated immunity" NARROW []
synonym: "up regulation of T cell mediated immunity" EXACT []
synonym: "up-regulation of T cell mediated immunity" EXACT []
synonym: "upregulation of T cell mediated immunity" EXACT []
is_a: GO:0002708 ! positive regulation of lymphocyte mediated immunity
is_a: GO:0002709 ! regulation of T cell mediated immunity
is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002456 ! T cell mediated immunity
relationship: positively_regulates GO:0002456 ! T cell mediated immunity

[Term]
id: GO:0002718
name: regulation of cytokine production involved in immune response
namespace: biological_process
alt_id: GO:0002739
alt_id: GO:0002742
def: "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add]
synonym: "regulation of cytokine biosynthetic process involved in immune response" NARROW []
synonym: "regulation of cytokine production during immune response" RELATED [GOC:dph]
synonym: "regulation of cytokine secretion involved in immune response" NARROW []
is_a: GO:0001817 ! regulation of cytokine production
is_a: GO:0002700 ! regulation of production of molecular mediator of immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002367 ! cytokine production involved in immune response
relationship: regulates GO:0002367 ! cytokine production involved in immune response

[Term]
id: GO:0002719
name: negative regulation of cytokine production involved in immune response
namespace: biological_process
alt_id: GO:0002740
alt_id: GO:0002743
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response." [GOC:add]
synonym: "down regulation of cytokine production during immune response" RELATED []
synonym: "down-regulation of cytokine production during immune response" EXACT []
synonym: "downregulation of cytokine production during immune response" RELATED []
synonym: "inhibition of cytokine production during immune response" RELATED []
synonym: "negative regulation of cytokine biosynthetic process involved in immune response" NARROW []
synonym: "negative regulation of cytokine production during immune response" RELATED [GOC:dph]
synonym: "negative regulation of cytokine secretion involved in immune response" NARROW []
is_a: GO:0001818 ! negative regulation of cytokine production
is_a: GO:0002701 ! negative regulation of production of molecular mediator of immune response
is_a: GO:0002718 ! regulation of cytokine production involved in immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002367 ! cytokine production involved in immune response
relationship: negatively_regulates GO:0002367 ! cytokine production involved in immune response

[Term]
id: GO:0002720
name: positive regulation of cytokine production involved in immune response
namespace: biological_process
alt_id: GO:0002741
alt_id: GO:0002744
def: "Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add]
synonym: "activation of cytokine production during immune response" NARROW []
synonym: "positive regulation of cytokine biosynthetic process involved in immune response" NARROW []
synonym: "positive regulation of cytokine production during immune response" RELATED [GOC:dph]
synonym: "positive regulation of cytokine secretion involved in immune response" NARROW []
synonym: "stimulation of cytokine production during immune response" NARROW []
synonym: "up regulation of cytokine production during immune response" RELATED []
synonym: "up-regulation of cytokine production during immune response" RELATED []
synonym: "upregulation of cytokine production during immune response" RELATED []
is_a: GO:0001819 ! positive regulation of cytokine production
is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response
is_a: GO:0002718 ! regulation of cytokine production involved in immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002367 ! cytokine production involved in immune response
relationship: positively_regulates GO:0002367 ! cytokine production involved in immune response

[Term]
id: GO:0002724
name: regulation of T cell cytokine production
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of T cell cytokine production." [GOC:add]
synonym: "regulation of T lymphocyte cytokine production" EXACT []
synonym: "regulation of T-cell cytokine production" EXACT []
synonym: "regulation of T-lymphocyte cytokine production" EXACT []
is_a: GO:0002709 ! regulation of T cell mediated immunity
is_a: GO:0002718 ! regulation of cytokine production involved in immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002369 ! T cell cytokine production
relationship: regulates GO:0002369 ! T cell cytokine production

[Term]
id: GO:0002725
name: negative regulation of T cell cytokine production
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production." [GOC:add]
synonym: "down regulation of T cell cytokine production" EXACT []
synonym: "down-regulation of T cell cytokine production" EXACT []
synonym: "downregulation of T cell cytokine production" EXACT []
synonym: "inhibition of T cell cytokine production" NARROW []
synonym: "negative regulation of T lymphocyte cytokine production" EXACT []
synonym: "negative regulation of T-cell cytokine production" EXACT []
synonym: "negative regulation of T-lymphocyte cytokine production" EXACT []
is_a: GO:0002710 ! negative regulation of T cell mediated immunity
is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response
is_a: GO:0002724 ! regulation of T cell cytokine production
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002369 ! T cell cytokine production
relationship: negatively_regulates GO:0002369 ! T cell cytokine production

[Term]
id: GO:0002726
name: positive regulation of T cell cytokine production
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of T cell cytokine production." [GOC:add]
synonym: "activation of T cell cytokine production" NARROW []
synonym: "positive regulation of T lymphocyte cytokine production" EXACT []
synonym: "positive regulation of T-cell cytokine production" EXACT []
synonym: "positive regulation of T-lymphocyte cytokine production" EXACT []
synonym: "stimulation of T cell cytokine production" NARROW []
synonym: "up regulation of T cell cytokine production" EXACT []
synonym: "up-regulation of T cell cytokine production" EXACT []
synonym: "upregulation of T cell cytokine production" EXACT []
is_a: GO:0002711 ! positive regulation of T cell mediated immunity
is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response
is_a: GO:0002724 ! regulation of T cell cytokine production
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002369 ! T cell cytokine production
relationship: positively_regulates GO:0002369 ! T cell cytokine production

[Term]
id: GO:0002730
name: regulation of dendritic cell cytokine production
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add]
is_a: GO:0002703 ! regulation of leukocyte mediated immunity
is_a: GO:0002718 ! regulation of cytokine production involved in immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002371 ! dendritic cell cytokine production
relationship: regulates GO:0002371 ! dendritic cell cytokine production

[Term]
id: GO:0002731
name: negative regulation of dendritic cell cytokine production
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add]
synonym: "down regulation of dendritic cell cytokine production" EXACT []
synonym: "down-regulation of dendritic cell cytokine production" EXACT []
synonym: "downregulation of dendritic cell cytokine production" EXACT []
synonym: "inhibition of dendritic cell cytokine production" NARROW []
is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity
is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response
is_a: GO:0002730 ! regulation of dendritic cell cytokine production
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002371 ! dendritic cell cytokine production
relationship: negatively_regulates GO:0002371 ! dendritic cell cytokine production

[Term]
id: GO:0002732
name: positive regulation of dendritic cell cytokine production
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add]
synonym: "activation of dendritic cell cytokine production" NARROW []
synonym: "stimulation of dendritic cell cytokine production" NARROW []
synonym: "up regulation of dendritic cell cytokine production" EXACT []
synonym: "up-regulation of dendritic cell cytokine production" EXACT []
synonym: "upregulation of dendritic cell cytokine production" EXACT []
is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity
is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response
is_a: GO:0002730 ! regulation of dendritic cell cytokine production
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002371 ! dendritic cell cytokine production
relationship: positively_regulates GO:0002371 ! dendritic cell cytokine production

[Term]
id: GO:0002761
name: regulation of myeloid leukocyte differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add]
is_a: GO:0045637 ! regulation of myeloid cell differentiation
is_a: GO:1902105 ! regulation of leukocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002573 ! myeloid leukocyte differentiation
relationship: regulates GO:0002573 ! myeloid leukocyte differentiation

[Term]
id: GO:0002762
name: negative regulation of myeloid leukocyte differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add]
synonym: "down regulation of myeloid leukocyte differentiation" EXACT []
synonym: "down-regulation of myeloid leukocyte differentiation" EXACT []
synonym: "downregulation of myeloid leukocyte differentiation" EXACT []
synonym: "inhibition of myeloid leukocyte differentiation" NARROW []
is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation
is_a: GO:0045638 ! negative regulation of myeloid cell differentiation
is_a: GO:1902106 ! negative regulation of leukocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002573 ! myeloid leukocyte differentiation
relationship: negatively_regulates GO:0002573 ! myeloid leukocyte differentiation

[Term]
id: GO:0002763
name: positive regulation of myeloid leukocyte differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add]
synonym: "activation of myeloid leukocyte differentiation" NARROW []
synonym: "stimulation of myeloid leukocyte differentiation" NARROW []
synonym: "up regulation of myeloid leukocyte differentiation" EXACT []
synonym: "up-regulation of myeloid leukocyte differentiation" EXACT []
synonym: "upregulation of myeloid leukocyte differentiation" EXACT []
is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation
is_a: GO:0045639 ! positive regulation of myeloid cell differentiation
is_a: GO:1902107 ! positive regulation of leukocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002573 ! myeloid leukocyte differentiation
relationship: positively_regulates GO:0002573 ! myeloid leukocyte differentiation

[Term]
id: GO:0002790
name: peptide secretion
namespace: biological_process
def: "The controlled release of a peptide from a cell or a tissue." [GOC:add]
is_a: GO:0015833 ! peptide transport
is_a: GO:0046903 ! secretion
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input CHEBI:16670 ! peptide

[Term]
id: GO:0002791
name: regulation of peptide secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of peptide secretion." [GOC:add]
is_a: GO:0051046 ! regulation of secretion
is_a: GO:0090087 ! regulation of peptide transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002790 ! peptide secretion
relationship: regulates GO:0002790 ! peptide secretion

[Term]
id: GO:0002792
name: negative regulation of peptide secretion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion." [GOC:add]
synonym: "down regulation of peptide secretion" EXACT []
synonym: "down-regulation of peptide secretion" EXACT []
synonym: "downregulation of peptide secretion" EXACT []
synonym: "inhibition of peptide secretion" NARROW []
is_a: GO:0002791 ! regulation of peptide secretion
is_a: GO:0051048 ! negative regulation of secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002790 ! peptide secretion
relationship: negatively_regulates GO:0002790 ! peptide secretion

[Term]
id: GO:0002793
name: positive regulation of peptide secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of peptide secretion." [GOC:add]
synonym: "activation of peptide secretion" NARROW []
synonym: "stimulation of peptide secretion" NARROW []
synonym: "up regulation of peptide secretion" EXACT []
synonym: "up-regulation of peptide secretion" EXACT []
synonym: "upregulation of peptide secretion" EXACT []
is_a: GO:0002791 ! regulation of peptide secretion
is_a: GO:0051047 ! positive regulation of secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002790 ! peptide secretion
relationship: positively_regulates GO:0002790 ! peptide secretion

[Term]
id: GO:0002819
name: regulation of adaptive immune response
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response." [GOC:add]
is_a: GO:0050776 ! regulation of immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002250 ! adaptive immune response
relationship: regulates GO:0002250 ! adaptive immune response

[Term]
id: GO:0002820
name: negative regulation of adaptive immune response
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response." [GOC:add]
synonym: "down regulation of adaptive immune response" EXACT []
synonym: "down-regulation of adaptive immune response" EXACT []
synonym: "downregulation of adaptive immune response" EXACT []
synonym: "inhibition of adaptive immune response" NARROW []
is_a: GO:0002819 ! regulation of adaptive immune response
is_a: GO:0050777 ! negative regulation of immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002250 ! adaptive immune response
relationship: negatively_regulates GO:0002250 ! adaptive immune response

[Term]
id: GO:0002821
name: positive regulation of adaptive immune response
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response." [GOC:add]
synonym: "activation of adaptive immune response" NARROW []
synonym: "stimulation of adaptive immune response" NARROW []
synonym: "up regulation of adaptive immune response" EXACT []
synonym: "up-regulation of adaptive immune response" EXACT []
synonym: "upregulation of adaptive immune response" EXACT []
is_a: GO:0002819 ! regulation of adaptive immune response
is_a: GO:0050778 ! positive regulation of immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002250 ! adaptive immune response
relationship: positively_regulates GO:0002250 ! adaptive immune response

[Term]
id: GO:0002822
name: regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu]
is_a: GO:0002819 ! regulation of adaptive immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
relationship: in_taxon NCBITaxon:7776 {all_only="true"} ! Gnathostomata <vertebrates>
relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata <vertebrates>
relationship: regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

[Term]
id: GO:0002823
name: negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu]
is_a: GO:0002820 ! negative regulation of adaptive immune response
is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
relationship: negatively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

[Term]
id: GO:0002824
name: positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu]
is_a: GO:0002821 ! positive regulation of adaptive immune response
is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
relationship: positively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

[Term]
id: GO:0002831
name: regulation of response to biotic stimulus
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus." [GOC:add]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009607 ! response to biotic stimulus
relationship: regulates GO:0009607 ! response to biotic stimulus

[Term]
id: GO:0002832
name: negative regulation of response to biotic stimulus
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus." [GOC:add]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "down regulation of response to biotic stimulus" EXACT []
synonym: "down-regulation of response to biotic stimulus" EXACT []
synonym: "downregulation of response to biotic stimulus" EXACT []
synonym: "inhibition of response to biotic stimulus" NARROW []
is_a: GO:0002831 ! regulation of response to biotic stimulus
is_a: GO:0048585 ! negative regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009607 ! response to biotic stimulus
relationship: negatively_regulates GO:0009607 ! response to biotic stimulus

[Term]
id: GO:0002833
name: positive regulation of response to biotic stimulus
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus." [GOC:add]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "activation of response to biotic stimulus" NARROW []
synonym: "stimulation of response to biotic stimulus" NARROW []
synonym: "up regulation of response to biotic stimulus" EXACT []
synonym: "up-regulation of response to biotic stimulus" EXACT []
synonym: "upregulation of response to biotic stimulus" EXACT []
is_a: GO:0002831 ! regulation of response to biotic stimulus
is_a: GO:0048584 ! positive regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009607 ! response to biotic stimulus
relationship: positively_regulates GO:0009607 ! response to biotic stimulus

[Term]
id: GO:0002886
name: regulation of myeloid leukocyte mediated immunity
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add]
is_a: GO:0002703 ! regulation of leukocyte mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002444 ! myeloid leukocyte mediated immunity
relationship: regulates GO:0002444 ! myeloid leukocyte mediated immunity

[Term]
id: GO:0002887
name: negative regulation of myeloid leukocyte mediated immunity
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add]
synonym: "down regulation of myeloid leukocyte mediated immunity" EXACT []
synonym: "down-regulation of myeloid leukocyte mediated immunity" EXACT []
synonym: "downregulation of myeloid leukocyte mediated immunity" EXACT []
synonym: "inhibition of myeloid leukocyte mediated immunity" NARROW []
is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity
is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002444 ! myeloid leukocyte mediated immunity
relationship: negatively_regulates GO:0002444 ! myeloid leukocyte mediated immunity

[Term]
id: GO:0002888
name: positive regulation of myeloid leukocyte mediated immunity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add]
synonym: "activation of myeloid leukocyte mediated immunity" NARROW []
synonym: "stimulation of myeloid leukocyte mediated immunity" NARROW []
synonym: "up regulation of myeloid leukocyte mediated immunity" EXACT []
synonym: "up-regulation of myeloid leukocyte mediated immunity" EXACT []
synonym: "upregulation of myeloid leukocyte mediated immunity" EXACT []
is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity
is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002444 ! myeloid leukocyte mediated immunity
relationship: positively_regulates GO:0002444 ! myeloid leukocyte mediated immunity

[Term]
id: GO:0002932
name: tendon sheath development
namespace: biological_process
def: "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move." [PMID:20696843]
is_a: GO:0061448 ! connective tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000304 ! tendon sheath
relationship: part_of GO:0035989 ! tendon development
relationship: results_in_development_of UBERON:0000304 ! tendon sheath
created_by: hjd
creation_date: 2012-04-23T02:11:22Z

[Term]
id: GO:0003002
name: regionalization
namespace: biological_process
def: "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:isa_complete]
synonym: "pattern formation" RELATED [GOC:dph]
is_a: GO:0007389 ! pattern specification process

[Term]
id: GO:0003006
name: developmental process involved in reproduction
namespace: biological_process
def: "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring." [GOC:dph, GOC:isa_complete]
synonym: "puberty" NARROW [GOC:dph]
synonym: "reproductive developmental process" RELATED [GOC:dph, GOC:tb]
is_a: GO:0022414 ! reproductive process
is_a: GO:0032502 ! developmental process
intersection_of: GO:0032502 ! developmental process
intersection_of: part_of GO:0000003 ! reproduction

[Term]
id: GO:0003007
name: heart morphogenesis
namespace: biological_process
def: "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:dph, GOC:isa_complete]
synonym: "cardiac morphogenesis" RELATED []
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0007100 ! primary circulatory organ
relationship: part_of GO:0007507 ! heart development
relationship: results_in_morphogenesis_of UBERON:0007100 ! primary circulatory organ

[Term]
id: GO:0003008
name: system process
namespace: biological_process
def: "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." [GOC:mtg_cardio]
synonym: "organ system process" EXACT []
is_a: GO:0032501 ! multicellular organismal process

[Term]
id: GO:0003009
name: skeletal muscle contraction
namespace: biological_process
def: "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control." [GOC:mtg_cardio, GOC:mtg_muscle]
is_a: GO:0006941 ! striated muscle contraction
intersection_of: GO:0006936 ! muscle contraction
intersection_of: occurs_in UBERON:0001134 ! skeletal muscle tissue
relationship: occurs_in UBERON:0001134 ! skeletal muscle tissue
relationship: part_of GO:0050881 ! musculoskeletal movement

[Term]
id: GO:0003012
name: muscle system process
namespace: biological_process
def: "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." [GOC:mtg_cardio]
subset: goslim_drosophila
subset: goslim_generic
synonym: "muscle physiological process" RELATED []
is_a: GO:0003008 ! system process

[Term]
id: GO:0003013
name: circulatory system process
namespace: biological_process
def: "A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism." [GOC:mtg_cardio]
subset: goslim_chembl
subset: goslim_generic
xref: Wikipedia:Circulatory_system
is_a: GO:0003008 ! system process

[Term]
id: GO:0003014
name: renal system process
namespace: biological_process
def: "A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)." [GOC:cjm, GOC:mtg_cardio, GOC:mtg_kidney_jan10]
subset: goslim_generic
synonym: "excretory system process" EXACT []
synonym: "kidney system process" RELATED []
is_a: GO:0003008 ! system process

[Term]
id: GO:0003015
name: heart process
namespace: biological_process
def: "A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:mtg_cardio]
synonym: "cardiac process" RELATED []
is_a: GO:0003013 ! circulatory system process

[Term]
id: GO:0003016
name: respiratory system process
namespace: biological_process
alt_id: GO:0010802
def: "A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange." [GOC:dph, GOC:mtg_cardio, GOC:tb]
subset: goslim_generic
synonym: "respiratory gaseous exchange" EXACT []
is_a: GO:0003008 ! system process
relationship: part_of GO:0007585 ! respiratory gaseous exchange by respiratory system

[Term]
id: GO:0003032
name: detection of oxygen
namespace: biological_process
def: "The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal." [GOC:mtg_cardio]
is_a: GO:0009593 ! detection of chemical stimulus
is_a: GO:0070482 ! response to oxygen levels

[Term]
id: GO:0003096
name: renal sodium ion transport
namespace: biological_process
def: "The directed movement of sodium ions (Na+) by the renal system." [GOC:mtg_cardio]
is_a: GO:0003014 ! renal system process
is_a: GO:0006814 ! sodium ion transport
intersection_of: GO:0006814 ! sodium ion transport
intersection_of: occurs_in UBERON:0001008 ! renal system
relationship: occurs_in UBERON:0001008 ! renal system

[Term]
id: GO:0003131
name: mesodermal-endodermal cell signaling
namespace: biological_process
def: "Any process that mediates the transfer of information from mesodermal cells to endodermal cells." [GOC:mtg_heart]
synonym: "mesodermal-endodermal cell signalling" EXACT [GOC:mah]
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: has_end_location CL:0000223 ! endodermal cell
intersection_of: has_start_location CL:0000222 ! mesodermal cell
relationship: has_end_location CL:0000223 ! endodermal cell
relationship: has_start_location CL:0000222 ! mesodermal cell
created_by: tb
creation_date: 2009-09-22T03:07:34Z

[Term]
id: GO:0003133
name: endodermal-mesodermal cell signaling
namespace: biological_process
def: "Any process that mediates the transfer of information from endodermal cells to mesodermal cells." [GOC:mtg_heart]
synonym: "endodermal-mesodermal cell signalling" EXACT [GOC:mah]
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: has_end_location CL:0000222 ! mesodermal cell
intersection_of: has_start_location CL:0000223 ! endodermal cell
relationship: has_end_location CL:0000222 ! mesodermal cell
relationship: has_start_location CL:0000223 ! endodermal cell
created_by: tb
creation_date: 2009-09-22T03:10:29Z

[Term]
id: GO:0003142
name: cardiogenic plate morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field." [GOC:mtg_heart]
synonym: "cardiac crescent morphogenesis" EXACT [GOC:mtg_heart]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004139 ! cardiogenic plate
relationship: part_of GO:0003007 ! heart morphogenesis
relationship: results_in_morphogenesis_of UBERON:0004139 ! cardiogenic plate
created_by: tb
creation_date: 2009-09-22T04:12:18Z

[Term]
id: GO:0003143
name: embryonic heart tube morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart]
is_a: GO:0048598 ! embryonic morphogenesis
is_a: GO:0060562 ! epithelial tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004141 ! heart tube
relationship: part_of GO:0003007 ! heart morphogenesis
relationship: part_of GO:0035050 ! embryonic heart tube development
relationship: part_of GO:0048562 ! embryonic organ morphogenesis
relationship: results_in_morphogenesis_of UBERON:0004141 ! heart tube
created_by: tb
creation_date: 2009-09-22T04:21:17Z

[Term]
id: GO:0003144
name: embryonic heart tube formation
namespace: biological_process
def: "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart]
is_a: GO:0001838 ! embryonic epithelial tube formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0004141 ! heart tube
relationship: part_of GO:0003143 ! embryonic heart tube morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0004141 ! heart tube
created_by: tb
creation_date: 2009-09-22T04:22:34Z

[Term]
id: GO:0003145
name: embryonic heart tube formation via epithelial folding
namespace: biological_process
def: "The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis." [GOC:mtg_heart]
is_a: GO:0003144 ! embryonic heart tube formation
created_by: tb
creation_date: 2009-09-22T04:26:03Z

[Term]
id: GO:0003147
name: neural crest cell migration involved in heart formation
namespace: biological_process
def: "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation." [GOC:mtg_heart]
is_a: GO:0001755 ! neural crest cell migration
is_a: GO:0060974 ! cell migration involved in heart formation
intersection_of: GO:0001755 ! neural crest cell migration
intersection_of: part_of GO:0060914 ! heart formation
relationship: part_of GO:0061308 ! cardiac neural crest cell development involved in heart development
created_by: tb
creation_date: 2009-09-22T04:29:55Z

[Term]
id: GO:0003148
name: outflow tract septum morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract." [GOC:mtg_heart]
is_a: GO:0060411 ! cardiac septum morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004142 ! outflow tract septum
relationship: part_of GO:0003151 ! outflow tract morphogenesis
relationship: results_in_morphogenesis_of UBERON:0004142 ! outflow tract septum
created_by: tb
creation_date: 2009-09-22T07:51:01Z

[Term]
id: GO:0003149
name: membranous septum morphogenesis
namespace: biological_process
def: "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum." [GOC:mtg_heart]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004666 ! interventricular septum membranous part
relationship: part_of GO:0060412 ! ventricular septum morphogenesis
relationship: results_in_morphogenesis_of UBERON:0004666 ! interventricular septum membranous part
created_by: tb
creation_date: 2009-09-22T07:51:41Z

[Term]
id: GO:0003150
name: muscular septum morphogenesis
namespace: biological_process
def: "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum." [GOC:mtg_heart]
is_a: GO:0060415 ! muscle tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004667 ! interventricular septum muscular part
relationship: part_of GO:0060412 ! ventricular septum morphogenesis
relationship: results_in_morphogenesis_of UBERON:0004667 ! interventricular septum muscular part
created_by: tb
creation_date: 2009-09-22T07:53:28Z

[Term]
id: GO:0003151
name: outflow tract morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_heart, UBERON:0004145]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004145 ! outflow tract
relationship: part_of GO:0003007 ! heart morphogenesis
relationship: results_in_morphogenesis_of UBERON:0004145 ! outflow tract
created_by: tb
creation_date: 2009-09-22T07:59:24Z

[Term]
id: GO:0003152
name: morphogenesis of an epithelial fold involved in embryonic heart tube formation
namespace: biological_process
def: "The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation." [GOC:mtg_heart]
is_a: GO:0048598 ! embryonic morphogenesis
is_a: GO:0060571 ! morphogenesis of an epithelial fold
intersection_of: GO:0060571 ! morphogenesis of an epithelial fold
intersection_of: part_of GO:0003144 ! embryonic heart tube formation
relationship: part_of GO:0003145 ! embryonic heart tube formation via epithelial folding
created_by: tb
creation_date: 2009-09-23T10:10:24Z

[Term]
id: GO:0003156
name: regulation of animal organ formation
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment." [GOC:dph, GOC:mtg_heart, GOC:tb]
is_a: GO:2000027 ! regulation of animal organ morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048645 ! animal organ formation
relationship: regulates GO:0048645 ! animal organ formation
created_by: tb
creation_date: 2009-09-30T11:21:09Z

[Term]
id: GO:0003157
name: endocardium development
namespace: biological_process
def: "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002165 ! endocardium
relationship: part_of GO:0007507 ! heart development
relationship: results_in_development_of UBERON:0002165 ! endocardium
created_by: dph
creation_date: 2009-10-01T12:42:27Z

[Term]
id: GO:0003158
name: endothelium development
namespace: biological_process
def: "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart]
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001986 ! endothelium
relationship: results_in_development_of UBERON:0001986 ! endothelium
created_by: dph
creation_date: 2009-10-01T12:50:57Z

[Term]
id: GO:0003159
name: morphogenesis of an endothelium
namespace: biological_process
def: "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart]
is_a: GO:0002009 ! morphogenesis of an epithelium
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001986 ! endothelium
relationship: part_of GO:0003158 ! endothelium development
relationship: results_in_morphogenesis_of UBERON:0001986 ! endothelium
created_by: dph
creation_date: 2009-10-01T01:34:06Z

[Term]
id: GO:0003160
name: endocardium morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002165 ! endocardium
relationship: part_of GO:0003157 ! endocardium development
relationship: results_in_morphogenesis_of UBERON:0002165 ! endocardium
created_by: dph
creation_date: 2009-10-01T01:37:26Z

[Term]
id: GO:0003161
name: cardiac conduction system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat." [GOC:mtg_heart]
synonym: "cardiac impulse conducting system development" EXACT [GOC:mtg_heart]
synonym: "heart conduction system development" EXACT [GOC:mtg_heart]
is_a: GO:0048738 ! cardiac muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002350 ! conducting system of heart
relationship: results_in_development_of UBERON:0002350 ! conducting system of heart
created_by: dph
creation_date: 2009-10-01T01:57:16Z

[Term]
id: GO:0003162
name: atrioventricular node development
namespace: biological_process
def: "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system." [GOC:mtg_heart]
synonym: "AV node development" EXACT [GOC:mtg_heart]
is_a: GO:0048738 ! cardiac muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002352 ! atrioventricular node
relationship: part_of GO:0003161 ! cardiac conduction system development
relationship: results_in_development_of UBERON:0002352 ! atrioventricular node
created_by: dph
creation_date: 2009-10-01T02:05:13Z

[Term]
id: GO:0003163
name: sinoatrial node development
namespace: biological_process
def: "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node." [GOC:mtg_heart]
synonym: "SA node development" EXACT [GOC:mtg_heart]
synonym: "SAN development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "sinus node development" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
is_a: GO:0003228 ! atrial cardiac muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002351 ! sinoatrial node
relationship: part_of GO:0003161 ! cardiac conduction system development
relationship: results_in_development_of UBERON:0002351 ! sinoatrial node
created_by: dph
creation_date: 2009-10-01T02:06:09Z

[Term]
id: GO:0003164
name: His-Purkinje system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart]
is_a: GO:0003229 ! ventricular cardiac muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004146 ! His-Purkinje system
relationship: part_of GO:0003161 ! cardiac conduction system development
relationship: results_in_development_of UBERON:0004146 ! His-Purkinje system
created_by: dph
creation_date: 2009-10-01T02:07:12Z

[Term]
id: GO:0003165
name: Purkinje myocyte development
namespace: biological_process
def: "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart]
synonym: "cardiac Purkinje fiber development" EXACT []
is_a: GO:0003229 ! ventricular cardiac muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002354 ! cardiac Purkinje fiber
relationship: part_of GO:0003164 ! His-Purkinje system development
relationship: results_in_development_of UBERON:0002354 ! cardiac Purkinje fiber
created_by: dph
creation_date: 2009-10-01T02:07:50Z

[Term]
id: GO:0003168
name: Purkinje myocyte differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart]
synonym: "cardiac Purkinje fiber cell differentiation" EXACT []
is_a: GO:0060932 ! His-Purkinje system cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002068 ! Purkinje myocyte
relationship: part_of GO:0003165 ! Purkinje myocyte development
relationship: results_in_acquisition_of_features_of CL:0002068 ! Purkinje myocyte
created_by: dph
creation_date: 2009-10-01T02:49:54Z

[Term]
id: GO:0003169
name: coronary vein morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of veins of the heart are generated and organized." [GOC:mtg_heart]
is_a: GO:0048845 ! venous blood vessel morphogenesis
is_a: GO:0060977 ! coronary vasculature morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004148 ! cardiac vein
relationship: results_in_morphogenesis_of UBERON:0004148 ! cardiac vein
created_by: dph
creation_date: 2009-10-08T10:45:41Z

[Term]
id: GO:0003197
name: endocardial cushion development
namespace: biological_process
def: "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart]
is_a: GO:0060485 ! mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002062 ! endocardial cushion
relationship: part_of GO:0007507 ! heart development
relationship: results_in_development_of UBERON:0002062 ! endocardial cushion
created_by: dph
creation_date: 2009-10-08T01:17:43Z

[Term]
id: GO:0003203
name: endocardial cushion morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart]
is_a: GO:0072132 ! mesenchyme morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002062 ! endocardial cushion
relationship: part_of GO:0003007 ! heart morphogenesis
relationship: part_of GO:0003197 ! endocardial cushion development
relationship: results_in_morphogenesis_of UBERON:0002062 ! endocardial cushion
created_by: dph
creation_date: 2009-10-08T01:43:22Z

[Term]
id: GO:0003204
name: cardiac skeleton development
namespace: biological_process
def: "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart." [GOC:mtg_heart]
synonym: "heart fibrous skeleton development" EXACT [GOC:mtg_heart]
is_a: GO:0061448 ! connective tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004292 ! cardiac skeleton
relationship: part_of GO:0007507 ! heart development
relationship: results_in_development_of UBERON:0004292 ! cardiac skeleton
created_by: dph
creation_date: 2009-10-13T09:05:04Z

[Term]
id: GO:0003205
name: cardiac chamber development
namespace: biological_process
def: "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004151 ! cardiac chamber
relationship: part_of GO:0007507 ! heart development
relationship: results_in_development_of UBERON:0004151 ! cardiac chamber
created_by: dph
creation_date: 2009-10-13T09:11:18Z

[Term]
id: GO:0003206
name: cardiac chamber morphogenesis
namespace: biological_process
def: "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart]
synonym: "heart chamber morphogenesis" EXACT [GOC:mtg_heart]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004151 ! cardiac chamber
relationship: part_of GO:0003007 ! heart morphogenesis
relationship: part_of GO:0003205 ! cardiac chamber development
relationship: results_in_morphogenesis_of UBERON:0004151 ! cardiac chamber
created_by: dph
creation_date: 2009-10-13T09:14:51Z

[Term]
id: GO:0003207
name: cardiac chamber formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart]
synonym: "heart chamber formation" EXACT [GOC:mtg_heart]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0004151 ! cardiac chamber
relationship: part_of GO:0003206 ! cardiac chamber morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0004151 ! cardiac chamber
created_by: dph
creation_date: 2009-10-13T09:29:13Z

[Term]
id: GO:0003208
name: cardiac ventricle morphogenesis
namespace: biological_process
def: "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart]
is_a: GO:0003206 ! cardiac chamber morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002082 ! cardiac ventricle
relationship: part_of GO:0003231 ! cardiac ventricle development
relationship: results_in_morphogenesis_of UBERON:0002082 ! cardiac ventricle
created_by: dph
creation_date: 2009-10-13T09:38:44Z

[Term]
id: GO:0003209
name: cardiac atrium morphogenesis
namespace: biological_process
def: "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart]
is_a: GO:0003206 ! cardiac chamber morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002081 ! cardiac atrium
relationship: part_of GO:0003230 ! cardiac atrium development
relationship: results_in_morphogenesis_of UBERON:0002081 ! cardiac atrium
created_by: dph
creation_date: 2009-10-13T09:39:44Z

[Term]
id: GO:0003210
name: cardiac atrium formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart]
is_a: GO:0003207 ! cardiac chamber formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002081 ! cardiac atrium
relationship: part_of GO:0003209 ! cardiac atrium morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002081 ! cardiac atrium
created_by: dph
creation_date: 2009-10-13T09:44:25Z

[Term]
id: GO:0003211
name: cardiac ventricle formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart]
is_a: GO:0003207 ! cardiac chamber formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002082 ! cardiac ventricle
relationship: part_of GO:0003208 ! cardiac ventricle morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002082 ! cardiac ventricle
created_by: dph
creation_date: 2009-10-13T09:46:27Z

[Term]
id: GO:0003212
name: cardiac left atrium morphogenesis
namespace: biological_process
def: "The process in which the left cardiac atrium is generated and organized." [GOC:mtg_heart]
is_a: GO:0003209 ! cardiac atrium morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002079 ! left cardiac atrium
relationship: results_in_morphogenesis_of UBERON:0002079 ! left cardiac atrium
created_by: dph
creation_date: 2009-10-13T09:48:16Z

[Term]
id: GO:0003213
name: cardiac right atrium morphogenesis
namespace: biological_process
def: "The process in which the right cardiac atrium is generated and organized." [GOC:mtg_heart]
is_a: GO:0003209 ! cardiac atrium morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002078 ! right cardiac atrium
relationship: results_in_morphogenesis_of UBERON:0002078 ! right cardiac atrium
created_by: dph
creation_date: 2009-10-13T09:49:03Z

[Term]
id: GO:0003214
name: cardiac left ventricle morphogenesis
namespace: biological_process
def: "The process in which the left cardiac ventricle is generated and organized." [GOC:mtg_heart]
is_a: GO:0003208 ! cardiac ventricle morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002084 ! heart left ventricle
relationship: results_in_morphogenesis_of UBERON:0002084 ! heart left ventricle
created_by: dph
creation_date: 2009-10-13T09:50:08Z

[Term]
id: GO:0003215
name: cardiac right ventricle morphogenesis
namespace: biological_process
def: "The process in which the right cardiac ventricle is generated and organized." [GOC:mtg_heart]
is_a: GO:0003208 ! cardiac ventricle morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002080 ! heart right ventricle
relationship: results_in_morphogenesis_of UBERON:0002080 ! heart right ventricle
created_by: dph
creation_date: 2009-10-13T09:50:57Z

[Term]
id: GO:0003216
name: cardiac left atrium formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts." [GOC:mtg_heart]
is_a: GO:0003210 ! cardiac atrium formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002079 ! left cardiac atrium
relationship: part_of GO:0003212 ! cardiac left atrium morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002079 ! left cardiac atrium
created_by: dph
creation_date: 2009-10-13T09:52:31Z

[Term]
id: GO:0003217
name: cardiac right atrium formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts." [GOC:mtg_heart]
is_a: GO:0003210 ! cardiac atrium formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002078 ! right cardiac atrium
relationship: part_of GO:0003213 ! cardiac right atrium morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002078 ! right cardiac atrium
created_by: dph
creation_date: 2009-10-13T09:53:12Z

[Term]
id: GO:0003218
name: cardiac left ventricle formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts." [GOC:mtg_heart]
is_a: GO:0003211 ! cardiac ventricle formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002084 ! heart left ventricle
relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002084 ! heart left ventricle
created_by: dph
creation_date: 2009-10-13T09:54:33Z

[Term]
id: GO:0003219
name: cardiac right ventricle formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts." [GOC:mtg_heart]
is_a: GO:0003211 ! cardiac ventricle formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002080 ! heart right ventricle
relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002080 ! heart right ventricle
created_by: dph
creation_date: 2009-10-13T09:55:38Z

[Term]
id: GO:0003220
name: left ventricular cardiac muscle tissue morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized." [GOC:mtg_heart]
synonym: "left ventricular myocardium morphogenesis" EXACT [GOC:mtg_heart]
is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003382 ! cardiac muscle of left ventricle
relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis
relationship: results_in_morphogenesis_of UBERON:0003382 ! cardiac muscle of left ventricle
created_by: dph
creation_date: 2009-10-13T10:18:05Z

[Term]
id: GO:0003221
name: right ventricular cardiac muscle tissue morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized." [GOC:mtg_heart]
synonym: "right ventricle myocardium morphogenesis" EXACT [GOC:mtg_heart]
is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003381 ! cardiac muscle of right ventricle
relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis
relationship: results_in_morphogenesis_of UBERON:0003381 ! cardiac muscle of right ventricle
created_by: dph
creation_date: 2009-10-13T10:26:33Z

[Term]
id: GO:0003222
name: ventricular trabecula myocardium morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized." [GOC:mtg_heart]
synonym: "trabecula carnea morphogenesis" RELATED [GOC:dph]
is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis
is_a: GO:0061384 ! heart trabecula morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004126 ! trabecular layer of ventricle
relationship: results_in_morphogenesis_of UBERON:0004126 ! trabecular layer of ventricle
created_by: dph
creation_date: 2009-10-13T10:33:00Z

[Term]
id: GO:0003225
name: left ventricular trabecular myocardium morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized." [GOC:mtg_heart]
is_a: GO:0003220 ! left ventricular cardiac muscle tissue morphogenesis
is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005064 ! left ventricular trabecular myocardium
relationship: results_in_morphogenesis_of UBERON:0005064 ! left ventricular trabecular myocardium
created_by: dph
creation_date: 2009-10-13T10:45:09Z

[Term]
id: GO:0003227
name: right ventricular trabecular myocardium morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the right ventricular myocardium are generated and organized." [GOC:mtg_heart]
is_a: GO:0003221 ! right ventricular cardiac muscle tissue morphogenesis
is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005066 ! right ventricular trabecular myocardium
relationship: results_in_morphogenesis_of UBERON:0005066 ! right ventricular trabecular myocardium
created_by: dph
creation_date: 2009-10-13T10:50:59Z

[Term]
id: GO:0003228
name: atrial cardiac muscle tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure." [GOC:mtg_heart]
synonym: "atrial myocardium development" EXACT [GOC:mtg_heart]
is_a: GO:0048738 ! cardiac muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004490 ! cardiac muscle tissue of atrium
relationship: results_in_development_of UBERON:0004490 ! cardiac muscle tissue of atrium
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22614" xsd:anyURI
created_by: dph
creation_date: 2009-10-13T10:53:18Z

[Term]
id: GO:0003229
name: ventricular cardiac muscle tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure." [GOC:mtg_heart]
synonym: "ventricular myocardium development" EXACT [GOC:mtg_heart]
is_a: GO:0048738 ! cardiac muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0018649 ! cardiac muscle tissue of ventricle
relationship: results_in_development_of UBERON:0018649 ! cardiac muscle tissue of ventricle
created_by: dph
creation_date: 2009-10-13T10:56:01Z

[Term]
id: GO:0003230
name: cardiac atrium development
namespace: biological_process
def: "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart]
is_a: GO:0003205 ! cardiac chamber development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002081 ! cardiac atrium
relationship: results_in_development_of UBERON:0002081 ! cardiac atrium
created_by: dph
creation_date: 2009-10-13T11:02:07Z

[Term]
id: GO:0003231
name: cardiac ventricle development
namespace: biological_process
def: "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart]
is_a: GO:0003205 ! cardiac chamber development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002082 ! cardiac ventricle
relationship: results_in_development_of UBERON:0002082 ! cardiac ventricle
created_by: dph
creation_date: 2009-10-13T11:03:16Z

[Term]
id: GO:0003235
name: sinus venosus development
namespace: biological_process
def: "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart]
is_a: GO:0003205 ! cardiac chamber development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002063 ! sinus venosus
relationship: results_in_development_of UBERON:0002063 ! sinus venosus
created_by: dph
creation_date: 2009-10-13T11:12:34Z

[Term]
id: GO:0003236
name: sinus venosus morphogenesis
namespace: biological_process
def: "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart]
is_a: GO:0003206 ! cardiac chamber morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002063 ! sinus venosus
relationship: part_of GO:0003235 ! sinus venosus development
relationship: results_in_morphogenesis_of UBERON:0002063 ! sinus venosus
created_by: dph
creation_date: 2009-10-13T11:16:52Z

[Term]
id: GO:0003237
name: sinus venosus formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart]
is_a: GO:0003207 ! cardiac chamber formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002063 ! sinus venosus
relationship: part_of GO:0003236 ! sinus venosus morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002063 ! sinus venosus
created_by: dph
creation_date: 2009-10-13T11:18:34Z

[Term]
id: GO:0003238
name: conus arteriosus development
namespace: biological_process
def: "The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart]
is_a: GO:0003205 ! cardiac chamber development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003983 ! conus arteriosus
relationship: results_in_development_of UBERON:0003983 ! conus arteriosus
created_by: dph
creation_date: 2009-10-13T11:20:57Z

[Term]
id: GO:0003239
name: conus arteriosus morphogenesis
namespace: biological_process
def: "The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart]
is_a: GO:0003206 ! cardiac chamber morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003983 ! conus arteriosus
relationship: part_of GO:0003238 ! conus arteriosus development
relationship: results_in_morphogenesis_of UBERON:0003983 ! conus arteriosus
created_by: dph
creation_date: 2009-10-13T11:25:04Z

[Term]
id: GO:0003240
name: conus arteriosus formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart]
is_a: GO:0003207 ! cardiac chamber formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003983 ! conus arteriosus
relationship: part_of GO:0003239 ! conus arteriosus morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0003983 ! conus arteriosus
created_by: dph
creation_date: 2009-10-13T11:25:47Z

[Term]
id: GO:0003241
name: growth involved in heart morphogenesis
namespace: biological_process
def: "Developmental growth that contributes to the shaping of the heart." [GOC:mtg_heart]
is_a: GO:0060560 ! developmental growth involved in morphogenesis
intersection_of: GO:0040007 ! growth
intersection_of: part_of GO:0003007 ! heart morphogenesis
relationship: part_of GO:0003007 ! heart morphogenesis
relationship: part_of GO:0060419 ! heart growth
created_by: dph
creation_date: 2009-10-13T11:28:46Z

[Term]
id: GO:0003245
name: cardiac muscle tissue growth involved in heart morphogenesis
namespace: biological_process
def: "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart." [GOC:mtg_heart]
is_a: GO:0003241 ! growth involved in heart morphogenesis
is_a: GO:0055017 ! cardiac muscle tissue growth
intersection_of: GO:0055017 ! cardiac muscle tissue growth
intersection_of: part_of GO:0003007 ! heart morphogenesis
relationship: part_of GO:0055008 ! cardiac muscle tissue morphogenesis
created_by: dph
creation_date: 2009-10-13T11:44:21Z

[Term]
id: GO:0003248
name: heart capillary growth
namespace: biological_process
def: "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle." [GOC:mtg_heart]
is_a: GO:0048589 ! developmental growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: results_in_growth_of UBERON:0006966 ! coronary capillary
relationship: part_of GO:0060419 ! heart growth
relationship: part_of GO:0060976 ! coronary vasculature development
relationship: results_in_growth_of UBERON:0006966 ! coronary capillary
created_by: dph
creation_date: 2009-10-13T11:53:12Z

[Term]
id: GO:0003253
name: cardiac neural crest cell migration involved in outflow tract morphogenesis
namespace: biological_process
def: "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract." [GOC:mtg_heart]
is_a: GO:0001755 ! neural crest cell migration
is_a: GO:0060973 ! cell migration involved in heart development
intersection_of: GO:0001755 ! neural crest cell migration
intersection_of: part_of GO:0003151 ! outflow tract morphogenesis
relationship: part_of GO:0061309 ! cardiac neural crest cell development involved in outflow tract morphogenesis
created_by: dph
creation_date: 2009-10-13T02:14:16Z

[Term]
id: GO:0003260
name: cardioblast migration
namespace: biological_process
def: "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart]
is_a: GO:0060974 ! cell migration involved in heart formation
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0002664 ! cardioblast
relationship: results_in_movement_of CL:0002664 ! cardioblast
created_by: dph
creation_date: 2009-10-15T01:52:25Z

[Term]
id: GO:0003272
name: endocardial cushion formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart, PMID:15797462]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002062 ! endocardial cushion
relationship: part_of GO:0003203 ! endocardial cushion morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002062 ! endocardial cushion
created_by: dph
creation_date: 2009-10-20T08:53:19Z

[Term]
id: GO:0003273
name: cell migration involved in endocardial cushion formation
namespace: biological_process
def: "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart]
is_a: GO:0060973 ! cell migration involved in heart development
intersection_of: GO:0016477 ! cell migration
intersection_of: part_of GO:0003272 ! endocardial cushion formation
relationship: part_of GO:0003272 ! endocardial cushion formation
created_by: dph
creation_date: 2009-10-20T09:08:44Z

[Term]
id: GO:0003275
name: apoptotic process involved in outflow tract morphogenesis
namespace: biological_process
def: "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_apoptosis, GOC:mtg_heart]
synonym: "apoptosis involved in outflow tract morphogenesis" NARROW []
is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis
intersection_of: GO:0006915 ! apoptotic process
intersection_of: part_of GO:0003151 ! outflow tract morphogenesis
relationship: part_of GO:0003151 ! outflow tract morphogenesis
created_by: dph
creation_date: 2009-10-20T09:30:01Z

[Term]
id: GO:0003277
name: apoptotic process involved in endocardial cushion morphogenesis
namespace: biological_process
def: "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_apoptosis, GOC:mtg_heart]
synonym: "apoptosis involved in endocardial cushion morphogenesis" NARROW []
is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis
intersection_of: GO:0006915 ! apoptotic process
intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis
relationship: part_of GO:0003203 ! endocardial cushion morphogenesis
created_by: dph
creation_date: 2009-10-20T09:37:03Z

[Term]
id: GO:0003278
name: apoptotic process involved in heart morphogenesis
namespace: biological_process
def: "Any apoptotic process that contributes to the shaping of the heart." [GOC:mtg_apoptosis, GOC:mtg_heart]
synonym: "apoptosis involved in heart morphogenesis" NARROW []
is_a: GO:0060561 ! apoptotic process involved in morphogenesis
intersection_of: GO:0006915 ! apoptotic process
intersection_of: part_of GO:0003007 ! heart morphogenesis
relationship: part_of GO:0003007 ! heart morphogenesis
created_by: dph
creation_date: 2009-10-20T09:40:22Z

[Term]
id: GO:0003279
name: cardiac septum development
namespace: biological_process
def: "The progression of a cardiac septum over time, from its initial formation to the mature structure." [GOC:mtg_heart]
synonym: "heart septum development" EXACT [GOC:mtg_heart]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002099 ! cardiac septum
relationship: part_of GO:0003205 ! cardiac chamber development
relationship: results_in_development_of UBERON:0002099 ! cardiac septum
created_by: dph
creation_date: 2009-10-20T09:45:13Z

[Term]
id: GO:0003281
name: ventricular septum development
namespace: biological_process
def: "The progression of the ventricular septum over time from its formation to the mature structure." [GOC:mtg_heart]
synonym: "interventricular septum development" EXACT [GOC:mtg_heart]
synonym: "septum inferius development" NARROW [GOC:mtg_heart]
is_a: GO:0003279 ! cardiac septum development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002094 ! interventricular septum
relationship: part_of GO:0003231 ! cardiac ventricle development
relationship: results_in_development_of UBERON:0002094 ! interventricular septum
created_by: dph
creation_date: 2009-10-20T10:04:51Z

[Term]
id: GO:0003283
name: atrial septum development
namespace: biological_process
def: "The progression of the atrial septum over time, from its initial formation to the mature structure." [GOC:mtg_heart]
is_a: GO:0003279 ! cardiac septum development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002085 ! interatrial septum
relationship: part_of GO:0003230 ! cardiac atrium development
relationship: results_in_development_of UBERON:0002085 ! interatrial septum
created_by: dph
creation_date: 2009-10-20T10:10:38Z

[Term]
id: GO:0003292
name: cardiac septum cell differentiation
namespace: biological_process
def: "The process in which an endocardial cushion cell becomes a cell of a cardiac septum." [GOC:mtg_heart]
is_a: GO:0035051 ! cardiocyte differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:2000022 ! cardiac septum cell
relationship: part_of GO:0003279 ! cardiac septum development
relationship: results_in_acquisition_of_features_of CL:2000022 ! cardiac septum cell
created_by: dph
creation_date: 2009-10-20T11:03:46Z

[Term]
id: GO:0003298
name: physiological muscle hypertrophy
namespace: biological_process
def: "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development." [GOC:mtg_heart]
is_a: GO:0014896 ! muscle hypertrophy
created_by: dph
creation_date: 2009-10-22T09:24:51Z

[Term]
id: GO:0003300
name: cardiac muscle hypertrophy
namespace: biological_process
def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division." [GOC:mtg_heart]
is_a: GO:0014897 ! striated muscle hypertrophy
created_by: dph
creation_date: 2009-10-22T10:33:56Z

[Term]
id: GO:0003301
name: physiological cardiac muscle hypertrophy
namespace: biological_process
def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart]
is_a: GO:0003298 ! physiological muscle hypertrophy
is_a: GO:0003300 ! cardiac muscle hypertrophy
relationship: part_of GO:0055017 ! cardiac muscle tissue growth
created_by: dph
creation_date: 2009-10-22T10:38:10Z

[Term]
id: GO:0003309
name: type B pancreatic cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph, PMID:11076772]
synonym: "pancreatic B cell differentiation" EXACT [GOC:mah]
synonym: "pancreatic beta cell differentiation" EXACT [GOC:dph]
is_a: GO:0035883 ! enteroendocrine cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000169 ! type B pancreatic cell
relationship: part_of GO:0031018 ! endocrine pancreas development
relationship: results_in_acquisition_of_features_of CL:0000169 ! type B pancreatic cell
created_by: dph
creation_date: 2009-10-26T09:27:23Z

[Term]
id: GO:0003310
name: pancreatic A cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph, PMID:11076772]
synonym: "pancreatic alpha cell differentiation" EXACT [GOC:dph]
is_a: GO:0035883 ! enteroendocrine cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000171 ! pancreatic A cell
relationship: part_of GO:0031018 ! endocrine pancreas development
relationship: results_in_acquisition_of_features_of CL:0000171 ! pancreatic A cell
created_by: dph
creation_date: 2009-10-26T09:28:05Z

[Term]
id: GO:0003311
name: pancreatic D cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph, PMID:11076772]
synonym: "pancreatic delta cell differentiation" EXACT [GOC:dph]
is_a: GO:0035883 ! enteroendocrine cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000173 ! pancreatic D cell
relationship: part_of GO:0031018 ! endocrine pancreas development
relationship: results_in_acquisition_of_features_of CL:0000173 ! pancreatic D cell
created_by: dph
creation_date: 2009-10-26T09:30:27Z

[Term]
id: GO:0003312
name: pancreatic PP cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph, PMID:11076772]
synonym: "pancreatic polypeptide-producing cell differentiation" EXACT [GOC:dph]
is_a: GO:0035883 ! enteroendocrine cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002275 ! pancreatic PP cell
relationship: part_of GO:0031018 ! endocrine pancreas development
relationship: results_in_acquisition_of_features_of CL:0002275 ! pancreatic PP cell
created_by: dph
creation_date: 2009-10-26T09:32:32Z

[Term]
id: GO:0003313
name: heart rudiment development
namespace: biological_process
def: "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." [GOC:mtg_heart]
synonym: "heart cone development" EXACT [GOC:mtg_heart]
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004291 ! heart rudiment
relationship: part_of GO:0035050 ! embryonic heart tube development
relationship: results_in_development_of UBERON:0004291 ! heart rudiment
created_by: dph
creation_date: 2009-10-27T08:32:40Z

[Term]
id: GO:0003314
name: heart rudiment morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the heart rudiment are generated and organized." [GOC:mtg_heart]
synonym: "heart cone morphogenesis" EXACT [GOC:mtg_heart]
is_a: GO:0002009 ! morphogenesis of an epithelium
is_a: GO:0048598 ! embryonic morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004291 ! heart rudiment
relationship: part_of GO:0003313 ! heart rudiment development
relationship: results_in_morphogenesis_of UBERON:0004291 ! heart rudiment
created_by: dph
creation_date: 2009-10-27T08:38:04Z

[Term]
id: GO:0003315
name: heart rudiment formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the heart rudiment." [GOC:mtg_heart]
synonym: "heart cone formation" EXACT [GOC:mtg_heart]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0004291 ! heart rudiment
relationship: part_of GO:0003314 ! heart rudiment morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0004291 ! heart rudiment
created_by: dph
creation_date: 2009-10-27T08:43:37Z

[Term]
id: GO:0003322
name: pancreatic A cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph]
synonym: "pancreatic alpha cell development" EXACT [GOC:dph]
is_a: GO:0002068 ! glandular epithelial cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000171 ! pancreatic A cell
relationship: part_of GO:0003310 ! pancreatic A cell differentiation
relationship: results_in_development_of CL:0000171 ! pancreatic A cell
created_by: dph
creation_date: 2009-11-02T08:13:55Z

[Term]
id: GO:0003323
name: type B pancreatic cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph]
synonym: "pancreatic B cell development" EXACT [GOC:mah]
synonym: "pancreatic beta cell development" EXACT [GOC:dph]
is_a: GO:0002068 ! glandular epithelial cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000169 ! type B pancreatic cell
relationship: part_of GO:0003309 ! type B pancreatic cell differentiation
relationship: results_in_development_of CL:0000169 ! type B pancreatic cell
created_by: dph
creation_date: 2009-11-02T08:20:11Z

[Term]
id: GO:0003324
name: pancreatic D cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph]
synonym: "pancreatic delta cell development" EXACT [GOC:dph]
is_a: GO:0002068 ! glandular epithelial cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000173 ! pancreatic D cell
relationship: part_of GO:0003311 ! pancreatic D cell differentiation
relationship: results_in_development_of CL:0000173 ! pancreatic D cell
created_by: dph
creation_date: 2009-11-02T08:23:26Z

[Term]
id: GO:0003325
name: pancreatic PP cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph]
is_a: GO:0002068 ! glandular epithelial cell development
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:0002275 ! pancreatic PP cell
relationship: part_of GO:0003312 ! pancreatic PP cell differentiation
relationship: results_in_development_of CL:0002275 ! pancreatic PP cell
created_by: dph
creation_date: 2009-11-02T08:25:03Z

[Term]
id: GO:0003333
name: amino acid transmembrane transport
namespace: biological_process
def: "The process in which an amino acid is transported across a membrane." [GOC:dph, GOC:tb]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "amino acid membrane transport" EXACT []
is_a: GO:0006865 ! amino acid transport
is_a: GO:1903825 ! organic acid transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:33709 ! amino acid
intersection_of: results_in_transport_across GO:0016020 ! membrane
created_by: dph
creation_date: 2009-11-02T02:36:11Z

[Term]
id: GO:0003337
name: mesenchymal to epithelial transition involved in metanephros morphogenesis
namespace: biological_process
def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf]
synonym: "metanephric mesenchyme to epithelial transition" RELATED [GOC:dph]
is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development
is_a: GO:0060231 ! mesenchymal to epithelial transition
is_a: GO:0072202 ! cell differentiation involved in metanephros development
intersection_of: GO:0060231 ! mesenchymal to epithelial transition
intersection_of: part_of GO:0003338 ! metanephros morphogenesis
relationship: part_of GO:0072283 ! metanephric renal vesicle morphogenesis
created_by: dph
creation_date: 2009-11-24T09:29:49Z

[Term]
id: GO:0003338
name: metanephros morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the metanephros are generated and organized." [GOC:dph, GOC:yaf]
is_a: GO:0060993 ! kidney morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000081 ! metanephros
relationship: part_of GO:0001656 ! metanephros development
relationship: results_in_morphogenesis_of UBERON:0000081 ! metanephros
created_by: dph
creation_date: 2009-11-24T09:32:09Z

[Term]
id: GO:0003339
name: regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph]
is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis
relationship: regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis
created_by: dph
creation_date: 2009-11-24T09:43:04Z

[Term]
id: GO:0003340
name: negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf]
is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis
relationship: negatively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis
created_by: dph
creation_date: 2009-11-24T09:46:12Z

[Term]
id: GO:0003341
name: cilium movement
namespace: biological_process
alt_id: GO:0036142
def: "The directed, self-propelled movement of a cilium." [GOC:dph, GOC:jl]
comment: Note that we deem cilium and microtubule-based flagellum to be equivalent.
synonym: "ciliary motility" RELATED []
synonym: "cilium beating" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb]
synonym: "flagellar motility" RELATED []
synonym: "flagellar movement" NARROW [GOC:bf]
synonym: "flagellum movement" NARROW []
synonym: "microtubule-based flagellum movement" EXACT []
is_a: GO:0007018 ! microtubule-based movement
intersection_of: GO:0007018 ! microtubule-based movement
intersection_of: process_has_causal_agent GO:0005874 ! microtubule
intersection_of: results_in_movement_of GO:0005929 ! cilium
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
relationship: results_in_movement_of GO:0005929 ! cilium
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI
property_value: RO:0002161 NCBITaxon:3176
property_value: RO:0002161 NCBITaxon:3312
property_value: RO:0002161 NCBITaxon:3378
property_value: RO:0002161 NCBITaxon:3398
property_value: RO:0002161 NCBITaxon:4890
property_value: RO:0002161 NCBITaxon:5782
created_by: dph
creation_date: 2009-11-24T09:56:26Z

[Term]
id: GO:0003342
name: proepicardium development
namespace: biological_process
def: "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum." [GOC:dph, PMID:18722343]
is_a: GO:0060485 ! mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004160 ! proepicardium
relationship: part_of GO:0003343 ! septum transversum development
relationship: results_in_development_of UBERON:0004160 ! proepicardium
created_by: dph
creation_date: 2009-12-01T10:30:17Z

[Term]
id: GO:0003343
name: septum transversum development
namespace: biological_process
def: "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme." [GOC:dph, PMID:18722343]
is_a: GO:0060485 ! mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004161 ! septum transversum
relationship: results_in_development_of UBERON:0004161 ! septum transversum
created_by: dph
creation_date: 2009-12-01T10:40:17Z

[Term]
id: GO:0003344
name: pericardium morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the pericardium is generated and organized." [GOC:dph, PMID:18722343]
is_a: GO:0002011 ! morphogenesis of an epithelial sheet
is_a: GO:0048598 ! embryonic morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002407 ! pericardium
relationship: part_of GO:0060039 ! pericardium development
relationship: results_in_morphogenesis_of UBERON:0002407 ! pericardium
created_by: dph
creation_date: 2009-12-01T10:46:34Z

[Term]
id: GO:0003348
name: cardiac endothelial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell." [GOC:dph, PMID:18722343]
is_a: GO:0035051 ! cardiocyte differentiation
is_a: GO:0045446 ! endothelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0010008 ! cardiac endothelial cell
relationship: results_in_acquisition_of_features_of CL:0010008 ! cardiac endothelial cell
created_by: dph
creation_date: 2009-12-01T11:12:05Z

[Term]
id: GO:0003352
name: regulation of cilium movement
namespace: biological_process
alt_id: GO:1900172
def: "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph]
comment: Note that we deem cilium and microtubule-based flagellum to be equivalent.
synonym: "regulation of flagellar movement" RELATED [GOC:TermGenie]
synonym: "regulation of flagellum movement" RELATED []
synonym: "regulation of microtubule-based flagellum movement" EXACT []
is_a: GO:0060632 ! regulation of microtubule-based movement
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003341 ! cilium movement
relationship: regulates GO:0003341 ! cilium movement
created_by: dph
creation_date: 2009-12-03T10:12:00Z

[Term]
id: GO:0003353
name: positive regulation of cilium movement
namespace: biological_process
alt_id: GO:1900174
def: "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph]
comment: Note that we deem cilium and microtubule-based flagellum to be equivalent.
synonym: "positive regulation of flagellar movement" RELATED [GOC:TermGenie]
synonym: "positive regulation of flagellum movement" RELATED []
synonym: "positive regulation of microtubule-based flagellum movement" EXACT []
is_a: GO:0003352 ! regulation of cilium movement
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003341 ! cilium movement
relationship: positively_regulates GO:0003341 ! cilium movement
created_by: dph
creation_date: 2009-12-03T10:16:10Z

[Term]
id: GO:0003354
name: negative regulation of cilium movement
namespace: biological_process
alt_id: GO:1900173
def: "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph]
comment: Note that we deem cilium and microtubule-based flagellum to be equivalent.
synonym: "negative regulation of flagellum movement" RELATED []
synonym: "negative regulation of microtubule-based flagellum movement" EXACT []
is_a: GO:0003352 ! regulation of cilium movement
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003341 ! cilium movement
relationship: negatively_regulates GO:0003341 ! cilium movement
created_by: dph
creation_date: 2009-12-03T10:17:47Z

[Term]
id: GO:0003357
name: noradrenergic neuron differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline." [GOC:dph]
synonym: "norepinephrine secreting neuron differentiation" EXACT [GOC:dph]
is_a: GO:0030182 ! neuron differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0008025 ! noradrenergic neuron
relationship: results_in_acquisition_of_features_of CL:0008025 ! noradrenergic neuron
created_by: dph
creation_date: 2009-12-03T10:34:30Z

[Term]
id: GO:0003358
name: noradrenergic neuron development
namespace: biological_process
def: "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph]
synonym: "norepinephrine secreting neuron development" EXACT [GOC:dph]
is_a: GO:0048666 ! neuron development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0008025 ! noradrenergic neuron
relationship: part_of GO:0003357 ! noradrenergic neuron differentiation
relationship: results_in_development_of CL:0008025 ! noradrenergic neuron
created_by: dph
creation_date: 2009-12-03T10:38:37Z

[Term]
id: GO:0003360
name: brainstem development
namespace: biological_process
def: "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord." [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002298 ! brainstem
relationship: results_in_development_of UBERON:0002298 ! brainstem
created_by: dph
creation_date: 2009-12-03T10:47:20Z

[Term]
id: GO:0003361
name: noradrenergic neuron differentiation involved in brainstem development
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem." [GOC:dph]
is_a: GO:0003357 ! noradrenergic neuron differentiation
intersection_of: GO:0003357 ! noradrenergic neuron differentiation
intersection_of: part_of GO:0003360 ! brainstem development
relationship: part_of GO:0003360 ! brainstem development
created_by: dph
creation_date: 2009-12-03T10:53:30Z

[Term]
id: GO:0003365
name: establishment of cell polarity involved in ameboidal cell migration
namespace: biological_process
def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0030010 ! establishment of cell polarity
intersection_of: GO:0030010 ! establishment of cell polarity
intersection_of: part_of GO:0001667 ! ameboidal-type cell migration
relationship: part_of GO:0001667 ! ameboidal-type cell migration
property_value: RO:0002161 NCBITaxon:4751
created_by: dph
creation_date: 2009-12-08T04:50:41Z

[Term]
id: GO:0003371
name: establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration
namespace: biological_process
def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity
intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity
intersection_of: part_of GO:0001667 ! ameboidal-type cell migration
relationship: part_of GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration
created_by: dph
creation_date: 2009-12-08T05:42:46Z

[Term]
id: GO:0003379
name: establishment of cell polarity involved in gastrulation cell migration
namespace: biological_process
def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration
intersection_of: GO:0030010 ! establishment of cell polarity
intersection_of: part_of GO:0042074 ! cell migration involved in gastrulation
relationship: part_of GO:0042074 ! cell migration involved in gastrulation
created_by: dph
creation_date: 2009-12-09T06:54:44Z

[Term]
id: GO:0003380
name: establishment or maintenance of cytoskeleton polarity involved in gastrulation
namespace: biological_process
def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0003371 ! establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration
intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity
intersection_of: part_of GO:0007369 ! gastrulation
relationship: part_of GO:0003379 ! establishment of cell polarity involved in gastrulation cell migration
created_by: dph
creation_date: 2009-12-09T07:10:57Z

[Term]
id: GO:0003381
name: epithelial cell morphogenesis involved in gastrulation
namespace: biological_process
def: "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0003382 ! epithelial cell morphogenesis
intersection_of: GO:0003382 ! epithelial cell morphogenesis
intersection_of: part_of GO:0007369 ! gastrulation
relationship: part_of GO:0007369 ! gastrulation
created_by: dph
creation_date: 2009-12-09T07:18:53Z

[Term]
id: GO:0003382
name: epithelial cell morphogenesis
namespace: biological_process
def: "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0000902 ! cell morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_maturation_of CL:0000066 ! epithelial cell
relationship: part_of GO:0002064 ! epithelial cell development
relationship: results_in_maturation_of CL:0000066 ! epithelial cell
created_by: dph
creation_date: 2009-12-09T07:21:06Z

[Term]
id: GO:0003403
name: optic vesicle formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0004128 ! optic vesicle
relationship: part_of GO:0003404 ! optic vesicle morphogenesis
relationship: part_of GO:0060900 ! embryonic camera-type eye formation
relationship: results_in_formation_of_anatomical_entity UBERON:0004128 ! optic vesicle
created_by: dph
creation_date: 2009-12-21T01:42:37Z

[Term]
id: GO:0003404
name: optic vesicle morphogenesis
namespace: biological_process
def: "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0048598 ! embryonic morphogenesis
is_a: GO:0048729 ! tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004128 ! optic vesicle
relationship: part_of GO:0048596 ! embryonic camera-type eye morphogenesis
relationship: results_in_morphogenesis_of UBERON:0004128 ! optic vesicle
created_by: dph
creation_date: 2009-12-21T01:54:34Z

[Term]
id: GO:0003407
name: neural retina development
namespace: biological_process
def: "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003902 ! retinal neural layer
relationship: part_of GO:0060041 ! retina development in camera-type eye
relationship: results_in_development_of UBERON:0003902 ! retinal neural layer
created_by: dph
creation_date: 2009-12-21T02:15:14Z

[Term]
id: GO:0003411
name: cell motility involved in camera-type eye morphogenesis
namespace: biological_process
def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0048870 ! cell motility
intersection_of: GO:0048870 ! cell motility
intersection_of: part_of GO:0048593 ! camera-type eye morphogenesis
relationship: part_of GO:0048593 ! camera-type eye morphogenesis
created_by: dph
creation_date: 2009-12-21T03:04:27Z

[Term]
id: GO:0003413
name: chondrocyte differentiation involved in endochondral bone morphogenesis
namespace: biological_process
def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0002062 ! chondrocyte differentiation
intersection_of: GO:0002062 ! chondrocyte differentiation
intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis
relationship: part_of GO:0060351 ! cartilage development involved in endochondral bone morphogenesis
created_by: dph
creation_date: 2009-12-22T08:39:58Z

[Term]
id: GO:0003414
name: chondrocyte morphogenesis involved in endochondral bone morphogenesis
namespace: biological_process
def: "The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0090171 ! chondrocyte morphogenesis
intersection_of: GO:0090171 ! chondrocyte morphogenesis
intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis
relationship: part_of GO:0003433 ! chondrocyte development involved in endochondral bone morphogenesis
created_by: dph
creation_date: 2009-12-22T08:42:55Z

[Term]
id: GO:0003416
name: endochondral bone growth
namespace: biological_process
def: "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0098868 ! bone growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: results_in_growth_of UBERON:0002513 ! endochondral bone
relationship: results_in_growth_of UBERON:0002513 ! endochondral bone
created_by: dph
creation_date: 2009-12-22T08:52:55Z

[Term]
id: GO:0003433
name: chondrocyte development involved in endochondral bone morphogenesis
namespace: biological_process
def: "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0002063 ! chondrocyte development
intersection_of: GO:0002063 ! chondrocyte development
intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis
relationship: part_of GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis
created_by: dph
creation_date: 2009-12-22T12:42:44Z

[Term]
id: GO:0003674
name: gene product or complex activity
name: molecular_function
namespace: molecular_function
alt_id: GO:0005554
def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." [GOC:pdt]
def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." [GOC:pdt]
comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.
comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.
comment: This is the same as GO molecular function
subset: goslim_candida
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "molecular function" EXACT []
is_a: BFO:0000015 ! process
disjoint_from: GO:0005575 ! cellular_component
disjoint_from: GO:0008150 ! biological process

[Term]
id: GO:0003824
name: catalytic activity
namespace: molecular_function
def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [GOC:vw, ISBN:0198506732]
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
synonym: "enzyme activity" EXACT [GOC:dph, GOC:tb]
xref: Wikipedia:Enzyme
is_a: GO:0003674 ! molecular_function

[Term]
id: GO:0004518
name: nuclease activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of ester linkages within nucleic acids." [ISBN:0198547684]
comment: Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', and 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' do not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0016788 ! hydrolase activity, acting on ester bonds

[Term]
id: GO:0004536
name: DNA nuclease activity
namespace: molecular_function
alt_id: GO:0004537
def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah, ISBN:0198547684]
synonym: "caspase-activated deoxyribonuclease activity" NARROW []
synonym: "deoxyribonuclease activity" EXACT []
xref: Reactome:R-HSA-211247 "Cleavage of DNA by DFF40"
xref: Reactome:R-HSA-5685994 "Long-range resection of DNA DSBs by EXO1 or DNA2"
xref: Reactome:R-HSA-6785986 "DNA nucleases unhook the interstrand crosslink (ICL)"
is_a: GO:0004518 ! nuclease activity
is_a: GO:0140097 ! catalytic activity, acting on DNA
relationship: part_of GO:0006259 ! DNA metabolic process

[Term]
id: GO:0005215
name: transporter activity
namespace: molecular_function
alt_id: GO:0005478
def: "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells." [GOC:ai, GOC:dgf]
comment: Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules.
subset: gocheck_do_not_annotate
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_prokaryote
synonym: "carrier" RELATED []
xref: Reactome:R-HSA-168313 "Virion-associated M2 protein mediated ion infusion"
xref: Reactome:R-HSA-178215 "SMAD7:SMURF1 complex is exported to the cytosol"
is_a: GO:0003674 ! molecular_function

[Term]
id: GO:0005275
name: amine transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0005279
def: "Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729]
synonym: "amine/amide/polyamine channel activity" BROAD []
synonym: "amine/polyamine transmembrane transporter activity" EXACT []
synonym: "amino acid-polyamine transmembrane transporter activity" EXACT []
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:32952 ! amine
relationship: has_primary_input CHEBI:32952 ! amine
relationship: part_of GO:0015837 ! amine transport

[Term]
id: GO:0005277
name: acetylcholine transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai]
xref: Reactome:R-HSA-264615 "Loading of acetylcholine in synaptic vesicles"
is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity
is_a: GO:0015101 ! organic cation transmembrane transporter activity
is_a: GO:1901375 ! acetate ester transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:15355 ! acetylcholine
relationship: has_primary_input CHEBI:15355 ! acetylcholine

[Term]
id: GO:0005310
name: dicarboxylic acid transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0005312
alt_id: GO:0015365
def: "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." [GOC:ai]
synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" RELATED []
synonym: "dicarboxylate carrier" NARROW []
synonym: "dicarboxylic acid permease activity" RELATED []
synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW []
xref: Reactome:R-HSA-1614546 "Sulfate is exported to the cytosol in exchange for dicarboxylate"
xref: Reactome:R-HSA-372843 "SLC25A10 mediates exchange of malate and phosphate"
is_a: GO:0005342 ! organic acid transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:35692 ! dicarboxylic acid
relationship: has_primary_input CHEBI:35692 ! dicarboxylic acid
relationship: part_of GO:0006835 ! dicarboxylic acid transport

[Term]
id: GO:0005319
name: lipid transporter activity
namespace: molecular_function
def: "Enables the directed movement of lipids into, out of or within a cell, or between cells." [GOC:ai]
synonym: "apolipoprotein" RELATED []
synonym: "lipophorin" NARROW []
xref: Reactome:R-HSA-1369028 "ABCAs mediate lipid efflux"
xref: Reactome:R-HSA-1369052 "ABCAs mediate lipid influx"
xref: Reactome:R-HSA-174786 "ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex"
xref: Reactome:R-HSA-5682285 "ABCA12 transports lipids from cytosol to extracellular region"
xref: Reactome:R-HSA-5682311 "Defective ABCA12 does not transport lipids from cytosol to extracellular region"
xref: Reactome:R-HSA-5683672 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body"
xref: Reactome:R-HSA-5683714 "ABCA3 transports PC, PG from ER membrane to lamellar body"
xref: Reactome:R-HSA-5688397 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body"
xref: Reactome:R-HSA-6801250 "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane"
xref: Reactome:R-HSA-8848053 "ABCA5 transports CHOL from lysosomal lumen to cytosol"
xref: Reactome:R-HSA-8866329 "MTTP lipidates APOB-100, forming a pre-VLDL"
is_a: GO:0005215 ! transporter activity
intersection_of: GO:0005215 ! transporter activity
intersection_of: has_primary_input CHEBI:18059 ! lipid
relationship: has_primary_input CHEBI:18059 ! lipid
relationship: part_of GO:0006869 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! lipid transport

[Term]
id: GO:0005326
name: neurotransmitter transmembrane transporter activity
namespace: molecular_function
def: "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai, ISBN:0198506732]
synonym: "neurotransmitter transporter activity" RELATED []
xref: Reactome:R-HSA-374896 "Uptake of Noradrenaline"
xref: Reactome:R-HSA-374919 "Noradrenaline clearance from the synaptic cleft"
relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of GO:0006836 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! neurotransmitter transport

[Term]
id: GO:0005342
name: organic acid transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage." [ISBN:0198506732]
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:64709 ! organic acid
relationship: has_primary_input CHEBI:64709 ! organic acid
relationship: part_of GO:1903825 ! organic acid transmembrane transport

[Term]
id: GO:0005355
name: glucose transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0015579
def: "Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
synonym: "galactose/glucose (methylgalactoside) porter activity" RELATED []
synonym: "glucose permease activity" EXACT []
synonym: "lactose/glucose efflux transporter activity" NARROW []
xref: Reactome:R-HSA-499981 "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2"
xref: Reactome:R-HSA-5653873 "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen"
is_a: GO:0015149 ! hexose transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:17234 ! glucose
relationship: has_primary_input CHEBI:17234 ! glucose
relationship: part_of GO:1904659 ! glucose transmembrane transport

[Term]
id: GO:0005575
name: cellular_component
namespace: cellular_component
alt_id: GO:0008372
def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt]
comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.
subset: goslim_candida
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "cell or subcellular entity" EXACT []
synonym: "cellular component" EXACT []
synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315]
xref: NIF_Subcellular:sao1337158144
is_a: BFO:0000040 ! material entity
disjoint_from: GO:0008150 ! biological process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17729" xsd:anyURI

[Term]
id: GO:0005576
name: extracellular region
namespace: cellular_component
def: "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." [GOC:go_curators]
comment: Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'.
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "extracellular" EXACT []
xref: Wikipedia:Extracellular
is_a: GO:0110165 ! cellular anatomical entity

[Term]
id: GO:0005577
name: fibrinogen complex
namespace: cellular_component
def: "A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds." [ISBN:0198547684]
synonym: "fibrinogen" EXACT []
synonym: "fibrinogen alpha chain" NARROW []
synonym: "fibrinogen beta chain" NARROW []
synonym: "fibrinogen gamma chain" NARROW []
is_a: GO:0032991 ! protein-containing complex
relationship: part_of GO:0005615 ! extracellular space

[Term]
id: GO:0005581
name: collagen trimer
namespace: cellular_component
def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, ISBN:0721639976, PMID:19693541, PMID:21421911]
xref: Wikipedia:Collagen
is_a: GO:0032991 ! protein-containing complex
relationship: in_taxon NCBITaxon:33208 {all_only="true", source="PMID:12382326"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 {source="PMID:12382326"} ! Metazoa

[Term]
id: GO:0005583
name: fibrillar collagen trimer
namespace: cellular_component
def: "Any triple helical collagen trimer that forms fibrils." [GOC:mah, ISBN:0721639976, PMID:21421911]
is_a: GO:0005581 ! collagen trimer
intersection_of: GO:0005581 ! collagen trimer
intersection_of: part_of GO:0098643 ! banded collagen fibril
disjoint_from: GO:0030936 ! transmembrane collagen trimer
relationship: part_of GO:0098643 ! banded collagen fibril

[Term]
id: GO:0005587
name: collagen type IV trimer
namespace: cellular_component
def: "A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes." [ISBN:0721639976, PMID:19693541, PMID:21421911]
xref: Wikipedia:Collagen_type_IV
is_a: GO:0098642 ! network-forming collagen trimer
is_a: GO:0098651 ! basement membrane collagen trimer

[Term]
id: GO:0005604
name: basement membrane
namespace: cellular_component
alt_id: GO:0005605
alt_id: GO:0008003
def: "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." [ISBN:0198547684, PMID:22505934]
comment: Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer.
synonym: "basal lamina" RELATED []
synonym: "basement lamina" RELATED []
synonym: "lamina densa" RELATED []
xref: Wikipedia:Basement_membrane
is_a: GO:0062023 ! collagen-containing extracellular matrix

[Term]
id: GO:0005615
name: extracellular space
namespace: cellular_component
def: "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684]
comment: Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term.
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_prokaryote
synonym: "intercellular space" RELATED []
xref: NIF_Subcellular:sao1425028079
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of GO:0005576 ! extracellular region

[Term]
id: GO:0005622
name: intracellular anatomical structure
namespace: cellular_component
def: "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732]
subset: gocheck_do_not_annotate
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_plant
synonym: "internal to cell" EXACT []
synonym: "intracellular" EXACT []
synonym: "nucleocytoplasm" RELATED [GOC:mah]
synonym: "protoplasm" EXACT []
synonym: "protoplast" RELATED [GOC:mah]
xref: Wikipedia:Intracellular
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of CL:0000000 ! cell
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17776" xsd:anyURI

[Term]
id: GO:0005634
name: nucleus
namespace: cellular_component
def: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators]
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "cell nucleus" EXACT []
synonym: "horsetail nucleus" NARROW [GOC:al, GOC:mah, GOC:vw, PMID:15030757]
xref: NIF_Subcellular:sao1702920020
xref: Wikipedia:Cell_nucleus
is_a: GO:0043231 ! intracellular membrane-bounded organelle
disjoint_from: GO:0005737 ! cytoplasm
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota

[Term]
id: GO:0005635
name: nuclear envelope
namespace: cellular_component
alt_id: GO:0005636
def: "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." [ISBN:0198547684]
subset: goslim_chembl
subset: goslim_generic
subset: goslim_plant
xref: Wikipedia:Nuclear_envelope
is_a: GO:0031967 ! organelle envelope
relationship: part_of GO:0005634 ! nucleus
relationship: part_of GO:0012505 ! endomembrane system

[Term]
id: GO:0005640
name: nuclear outer membrane
namespace: cellular_component
def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes." [ISBN:0198547684]
synonym: "nucleus outer envelope" EXACT []
synonym: "perinuclear membrane" EXACT []
xref: NIF_Subcellular:sao1617136075
is_a: GO:0031965 ! nuclear membrane
is_a: GO:0031968 ! organelle outer membrane
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0005634 ! nucleus
relationship: bounding_layer_of GO:0005634 ! nucleus
relationship: part_of GO:0042175 ! nuclear outer membrane-endoplasmic reticulum membrane network

[Term]
id: GO:0005694
name: chromosome
namespace: cellular_component
def: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [ISBN:0198547684]
comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "chromatid" RELATED []
synonym: "interphase chromosome" NARROW []
synonym: "prophase chromosome" NARROW []
xref: Wikipedia:Chromosome
is_a: GO:0043232 ! intracellular non-membrane-bounded organelle

[Term]
id: GO:0005730
name: nucleolus
namespace: cellular_component
def: "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." [ISBN:0198506732]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
xref: NIF_Subcellular:sao1820400233
xref: Wikipedia:Nucleolus
is_a: GO:0043232 ! intracellular non-membrane-bounded organelle
relationship: part_of GO:0031981 ! nuclear lumen

[Term]
id: GO:0005737
name: cytoplasm
namespace: cellular_component
def: "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_prokaryote
subset: goslim_yeast
xref: Wikipedia:Cytoplasm
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of GO:0005622 ! intracellular anatomical structure
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23023" xsd:anyURI

[Term]
id: GO:0005773
name: vacuole
namespace: cellular_component
def: "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." [GOC:mtg_sensu, ISBN:0198506732]
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "vacuolar carboxypeptidase Y" RELATED []
xref: Wikipedia:Vacuole
is_a: GO:0043231 ! intracellular membrane-bounded organelle
relationship: part_of GO:0005737 ! cytoplasm

[Term]
id: GO:0005774
name: vacuolar membrane
namespace: cellular_component
def: "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell." [GOC:ai]
is_a: GO:0098588 ! bounding membrane of organelle
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0005773 ! vacuole
relationship: bounding_layer_of GO:0005773 ! vacuole
relationship: part_of GO:0005773 ! vacuole

[Term]
id: GO:0005775
name: vacuolar lumen
namespace: cellular_component
def: "The volume enclosed within the vacuolar membrane." [ISBN:0198506732]
is_a: GO:0070013 ! intracellular organelle lumen
intersection_of: GO:0031974 ! membrane-enclosed lumen
intersection_of: part_of GO:0005773 ! vacuole
relationship: part_of GO:0005773 ! vacuole

[Term]
id: GO:0005794
name: Golgi apparatus
namespace: cellular_component
def: "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways." [ISBN:0198506732]
comment: Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon.
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "Golgi" BROAD []
synonym: "Golgi complex" EXACT []
synonym: "Golgi ribbon" NARROW []
xref: NIF_Subcellular:sao451912436
xref: Wikipedia:Golgi_apparatus
is_a: GO:0043231 ! intracellular membrane-bounded organelle
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
relationship: part_of GO:0005737 ! cytoplasm
relationship: part_of GO:0012505 ! endomembrane system

[Term]
id: GO:0005798
name: Golgi-associated vesicle
namespace: cellular_component
def: "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell." [GOC:mah]
comment: Note that this definition includes vesicles that are transiently associated with the Golgi.
synonym: "Golgi vesicle" RELATED []
synonym: "vesicular component" RELATED [NIF_Subcellular:sao138219748]
xref: NIF_Subcellular:sao819927218
is_a: GO:0031410 ! cytoplasmic vesicle

[Term]
id: GO:0005840
name: ribosome
namespace: cellular_component
alt_id: GO:0033279
def: "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins." [ISBN:0198506732]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046]
synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653]
synonym: "ribosomal RNA" RELATED []
xref: NIF_Subcellular:sao1429207766
xref: Wikipedia:Ribosome
is_a: GO:0043232 ! intracellular non-membrane-bounded organelle
is_a: PR:000050567 ! protein-containing material entity
relationship: capable_of_part_of GO:0006412 ! translation
relationship: has_part CHEBI:33697 ! ribonucleic acid

[Term]
id: GO:0005856
name: cytoskeleton
namespace: cellular_component
def: "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:mah, PMID:16959967, PMID:27419875]
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_prokaryote
subset: goslim_yeast
xref: Wikipedia:Cytoskeleton
is_a: GO:0043232 ! intracellular non-membrane-bounded organelle

[Term]
id: GO:0005874
name: microtubule
namespace: cellular_component
def: "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568]
subset: goslim_metagenomics
synonym: "microtubuli" EXACT []
synonym: "microtubulus" EXACT []
synonym: "neurotubule" NARROW [NIF_Subcellular:sao248349196]
xref: NIF_Subcellular:sao1846835077
xref: Wikipedia:Microtubule
is_a: GO:0099513 ! polymeric cytoskeletal fiber
relationship: part_of GO:0015630 ! microtubule cytoskeleton

[Term]
id: GO:0005879
name: axonemal microtubule
namespace: cellular_component
def: "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules." [GOC:cilia, ISBN:0815316194]
is_a: GO:0005881 ! cytoplasmic microtubule
intersection_of: GO:0005874 ! microtubule
intersection_of: part_of GO:0005930 ! axoneme
relationship: part_of GO:0005930 ! axoneme

[Term]
id: GO:0005880
name: nuclear microtubule
namespace: cellular_component
def: "Any microtubule in the nucleus of a cell." [GOC:mah]
is_a: GO:0005874 ! microtubule
intersection_of: GO:0005874 ! microtubule
intersection_of: part_of GO:0005634 ! nucleus
relationship: part_of GO:0005634 ! nucleus

[Term]
id: GO:0005881
name: cytoplasmic microtubule
namespace: cellular_component
def: "Any microtubule in the cytoplasm of a cell." [GOC:mah]
synonym: "non-spindle-associated astral microtubule" NARROW []
is_a: GO:0005874 ! microtubule
intersection_of: GO:0005874 ! microtubule
intersection_of: part_of GO:0005737 ! cytoplasm
relationship: part_of GO:0005737 ! cytoplasm

[Term]
id: GO:0005884
name: actin filament
namespace: cellular_component
def: "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." [GOC:mah, ISBN:0198506732, PMID:10666339]
synonym: "microfilament" EXACT []
xref: FMA:63850
xref: NIF_Subcellular:sao1588493326
xref: Wikipedia:Actin
is_a: GO:0099513 ! polymeric cytoskeletal fiber
relationship: part_of GO:0015629 ! actin cytoskeleton

[Term]
id: GO:0005886
name: plasma membrane
namespace: cellular_component
alt_id: GO:0005887
alt_id: GO:0005904
def: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363]
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_plant
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "bacterial inner membrane" NARROW []
synonym: "cell membrane" EXACT []
synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645]
synonym: "cytoplasmic membrane" EXACT []
synonym: "inner endospore membrane" NARROW []
synonym: "integral component of plasma membrane" NARROW []
synonym: "integral to plasma membrane" NARROW []
synonym: "juxtamembrane" BROAD []
synonym: "plasma membrane lipid bilayer" NARROW [GOC:mah]
synonym: "plasmalemma" EXACT []
xref: NIF_Subcellular:sao1663586795
xref: Wikipedia:Cell_membrane
is_a: GO:0016020 ! membrane
relationship: part_of GO:0071944 ! cell periphery

[Term]
id: GO:0005902
name: microvillus
namespace: cellular_component
def: "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells." [ISBN:0815316194]
comment: Note that this term refers to a projection from a single cell, and should not be confused with 'microvillus' as used to refer to a multicellular structure such as that found in the placenta.
subset: goslim_pir
synonym: "microvilli" RELATED [NIF_Subcellular:sao671419673]
xref: NIF_Subcellular:sao671419673
xref: Wikipedia:Microvillus
is_a: GO:0098858 ! actin-based cell projection
relationship: has_part GO:0032432 ! actin filament bundle
relationship: part_of CL:0000066 ! epithelial cell
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0005911
name: cell-cell junction
namespace: cellular_component
def: "A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects." [GOC:aruk, GOC:bc, GOC:dgh, GOC:hb, GOC:mah, PMID:21422226, PMID:28096264]
synonym: "cell-cell contact region" BROAD []
synonym: "cell-cell contact zone" BROAD []
synonym: "intercellular junction" EXACT [NIF_Subcellular:sao1395777368]
xref: NIF_Subcellular:sao1922892319
is_a: GO:0070161 ! anchoring junction
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22122" xsd:anyURI

[Term]
id: GO:0005929
name: cilium
namespace: cellular_component
alt_id: GO:0072372
def: "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body." [GOC:cilia, GOC:curators, GOC:kmv, GOC:vw, ISBN:0198547684, PMID:16824949, PMID:17009929, PMID:20144998]
comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms.
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pir
synonym: "eukaryotic flagellum" EXACT []
synonym: "flagellum" RELATED []
synonym: "microtubule-based flagellum" EXACT []
synonym: "primary cilium" NARROW []
xref: FMA:67181
xref: NIF_Subcellular:sao787716553
xref: Wikipedia:Cilium
is_a: GO:0043227 ! membrane-bounded organelle
is_a: GO:0120025 ! plasma membrane bounded cell projection
is_a: PR:000050567 ! protein-containing material entity
relationship: has_part GO:0030990 ! intraciliary transport particle
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
property_value: RO:0002161 NCBITaxon:3176
property_value: RO:0002161 NCBITaxon:3312
property_value: RO:0002161 NCBITaxon:3378
property_value: RO:0002161 NCBITaxon:3398
property_value: RO:0002161 NCBITaxon:4890
property_value: RO:0002161 NCBITaxon:5782

[Term]
id: GO:0005930
name: axoneme
namespace: cellular_component
alt_id: GO:0035085
alt_id: GO:0035086
def: "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, ISBN:0198547684]
comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.
subset: goslim_pir
synonym: "ciliary axoneme" EXACT []
synonym: "cilium axoneme" EXACT []
synonym: "flagellar axoneme" EXACT []
synonym: "flagellum axoneme" EXACT []
xref: Wikipedia:Axoneme
is_a: GO:0110165 ! cellular anatomical entity
relationship: has_part GO:0005874 ! microtubule
relationship: part_of GO:0005856 ! cytoskeleton
relationship: part_of GO:0097014 ! ciliary plasm

[Term]
id: GO:0005938
name: cell cortex
namespace: cellular_component
def: "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:mah, ISBN:0815316194]
subset: goslim_candida
subset: goslim_yeast
synonym: "cell periphery" RELATED []
synonym: "ectoplasm" NARROW []
synonym: "peripheral cytoplasm" RELATED []
xref: Wikipedia:Cell_cortex
is_a: GO:0005737 ! cytoplasm
intersection_of: GO:0005737 ! cytoplasm
intersection_of: part_of GO:0071944 ! cell periphery
relationship: part_of GO:0071944 ! cell periphery
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26298" xsd:anyURI

[Term]
id: GO:0005975
name: carbohydrate metabolic process
namespace: biological_process
alt_id: GO:0044261
alt_id: GO:0044723
def: "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [GOC:mah, ISBN:0198506732]
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_pombe
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "carbohydrate metabolism" EXACT []
xref: Wikipedia:Carbohydrate_metabolism
is_a: GO:0044238 ! primary metabolic process
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:16646 ! carbohydrate
relationship: has_primary_input_or_output CHEBI:16646 ! carbohydrate
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22880" xsd:anyURI
created_by: jl
creation_date: 2012-10-23T15:40:34Z

[Term]
id: GO:0005976
name: polysaccharide metabolic process
namespace: biological_process
alt_id: GO:0044263
def: "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [ISBN:0198547684]
subset: goslim_pir
synonym: "glycan metabolic process" NARROW []
synonym: "glycan metabolism" NARROW []
synonym: "multicellular organismal polysaccharide metabolic process" NARROW []
synonym: "polysaccharide metabolism" EXACT []
is_a: GO:0005975 ! carbohydrate metabolic process
is_a: GO:0043170 ! macromolecule metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:18154 ! polysaccharide
relationship: has_primary_input_or_output CHEBI:18154 ! polysaccharide

[Term]
id: GO:0005977
name: glycogen metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages." [ISBN:0198506732]
synonym: "glycogen metabolism" EXACT []
is_a: GO:0006112 ! energy reserve metabolic process
is_a: GO:0044042 ! glucan metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:28087 ! glycogen
relationship: has_primary_input_or_output CHEBI:28087 ! glycogen

[Term]
id: GO:0005978
name: glycogen biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732]
synonym: "glycogen anabolism" EXACT []
synonym: "glycogen biosynthesis" EXACT []
synonym: "glycogen formation" EXACT []
synonym: "glycogen synthesis" EXACT []
xref: MetaCyc:GLYCOGENSYNTH-PWY
is_a: GO:0005977 ! glycogen metabolic process
is_a: GO:0009250 ! glucan biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:28087 ! glycogen
relationship: has_primary_output CHEBI:28087 ! glycogen

[Term]
id: GO:0005979
name: regulation of glycogen biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators]
synonym: "regulation of glycogen anabolism" EXACT []
synonym: "regulation of glycogen biosynthesis" EXACT []
synonym: "regulation of glycogen formation" EXACT []
synonym: "regulation of glycogen synthesis" EXACT []
is_a: GO:0010962 ! regulation of glucan biosynthetic process
is_a: GO:0070873 ! regulation of glycogen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0005978 ! glycogen biosynthetic process
relationship: regulates GO:0005978 ! glycogen biosynthetic process

[Term]
id: GO:0005980
name: glycogen catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732]
synonym: "glycogen breakdown" EXACT []
synonym: "glycogen catabolism" EXACT []
synonym: "glycogen degradation" EXACT []
synonym: "glycogenolysis" EXACT [GOC:sl]
xref: MetaCyc:GLYCOCAT-PWY
is_a: GO:0005977 ! glycogen metabolic process
is_a: GO:0009251 ! glucan catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:28087 ! glycogen
relationship: has_primary_input CHEBI:28087 ! glycogen

[Term]
id: GO:0005981
name: regulation of glycogen catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators]
synonym: "regulation of glycogen breakdown" EXACT []
synonym: "regulation of glycogen catabolism" EXACT []
synonym: "regulation of glycogen degradation" EXACT []
synonym: "regulation of glycogenolysis" EXACT [GOC:sl]
is_a: GO:0043470 ! regulation of carbohydrate catabolic process
is_a: GO:0070873 ! regulation of glycogen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0005980 ! glycogen catabolic process
relationship: regulates GO:0005980 ! glycogen catabolic process

[Term]
id: GO:0005996
name: monosaccharide metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [ISBN:0198506732]
synonym: "monosaccharide metabolism" EXACT []
is_a: GO:0005975 ! carbohydrate metabolic process
is_a: GO:0044281 ! small molecule metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:35381 ! monosaccharide
relationship: has_primary_input_or_output CHEBI:35381 ! monosaccharide

[Term]
id: GO:0006006
name: glucose metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides." [ISBN:0198506732]
synonym: "cellular glucose metabolic process" EXACT [GOC:vw]
synonym: "glucose metabolism" EXACT []
is_a: GO:0019318 ! hexose metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:17234 ! glucose
relationship: has_primary_input_or_output CHEBI:17234 ! glucose

[Term]
id: GO:0006007
name: glucose catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose." [GOC:ai]
synonym: "glucose breakdown" EXACT []
synonym: "glucose catabolism" EXACT []
synonym: "glucose degradation" EXACT []
is_a: GO:0006006 ! glucose metabolic process
is_a: GO:0019320 ! hexose catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:17234 ! glucose
relationship: has_primary_input CHEBI:17234 ! glucose

[Term]
id: GO:0006022
name: aminoglycan metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732]
synonym: "aminoglycan metabolism" EXACT []
is_a: GO:0043170 ! macromolecule metabolic process
is_a: GO:1901135 ! carbohydrate derivative metabolic process
is_a: GO:1901564 ! organonitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:22506 ! aminoglycan
relationship: has_primary_input_or_output CHEBI:22506 ! aminoglycan

[Term]
id: GO:0006023
name: aminoglycan biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732]
synonym: "aminoglycan anabolism" EXACT []
synonym: "aminoglycan biosynthesis" EXACT []
synonym: "aminoglycan formation" EXACT []
synonym: "aminoglycan synthesis" EXACT []
is_a: GO:0006022 ! aminoglycan metabolic process
is_a: GO:0009059 ! macromolecule biosynthetic process
is_a: GO:1901137 ! carbohydrate derivative biosynthetic process
is_a: GO:1901566 ! organonitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:22506 ! aminoglycan
relationship: has_primary_output CHEBI:22506 ! aminoglycan

[Term]
id: GO:0006024
name: glycosaminoglycan biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." [ISBN:0192800981]
synonym: "glycosaminoglycan anabolism" EXACT []
synonym: "glycosaminoglycan biosynthesis" EXACT []
synonym: "glycosaminoglycan formation" EXACT []
synonym: "glycosaminoglycan synthesis" EXACT []
is_a: GO:0006023 ! aminoglycan biosynthetic process
is_a: GO:0030203 ! glycosaminoglycan metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:18085 ! glycosaminoglycan
relationship: has_primary_output CHEBI:18085 ! glycosaminoglycan

[Term]
id: GO:0006026
name: aminoglycan catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732]
synonym: "aminoglycan breakdown" EXACT []
synonym: "aminoglycan catabolism" EXACT []
synonym: "aminoglycan degradation" EXACT []
is_a: GO:0006022 ! aminoglycan metabolic process
is_a: GO:0009057 ! macromolecule catabolic process
is_a: GO:1901136 ! carbohydrate derivative catabolic process
is_a: GO:1901565 ! organonitrogen compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:22506 ! aminoglycan
relationship: has_primary_input CHEBI:22506 ! aminoglycan

[Term]
id: GO:0006027
name: glycosaminoglycan catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars." [ISBN:0192800981]
synonym: "glycosaminoglycan breakdown" EXACT []
synonym: "glycosaminoglycan catabolism" EXACT []
synonym: "glycosaminoglycan degradation" EXACT []
is_a: GO:0006026 ! aminoglycan catabolic process
is_a: GO:0030203 ! glycosaminoglycan metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:18085 ! glycosaminoglycan
relationship: has_primary_input CHEBI:18085 ! glycosaminoglycan

[Term]
id: GO:0006030
name: chitin metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732]
synonym: "beta-1,4-linked N-acetylglucosamine metabolic process" EXACT []
synonym: "beta-1,4-linked N-acetylglucosamine metabolism" EXACT []
synonym: "chitin metabolism" EXACT []
is_a: GO:0006022 ! aminoglycan metabolic process
is_a: GO:1901071 ! glucosamine-containing compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:17029 ! chitin
relationship: has_primary_input_or_output CHEBI:17029 ! chitin

[Term]
id: GO:0006031
name: chitin biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732]
synonym: "beta-1,4-linked N-acetylglucosamine biosynthesis" EXACT []
synonym: "beta-1,4-linked N-acetylglucosamine biosynthetic process" EXACT []
synonym: "chitin anabolism" EXACT []
synonym: "chitin biosynthesis" EXACT []
synonym: "chitin formation" EXACT []
synonym: "chitin synthesis" EXACT []
is_a: GO:0006023 ! aminoglycan biosynthetic process
is_a: GO:0006030 ! chitin metabolic process
is_a: GO:1901073 ! glucosamine-containing compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:17029 ! chitin
relationship: has_primary_output CHEBI:17029 ! chitin

[Term]
id: GO:0006032
name: chitin catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732]
synonym: "beta-1,4-linked N-acetylglucosamine catabolic process" EXACT []
synonym: "beta-1,4-linked N-acetylglucosamine catabolism" EXACT []
synonym: "chitin breakdown" EXACT []
synonym: "chitin catabolism" EXACT []
synonym: "chitin degradation" EXACT []
is_a: GO:0006026 ! aminoglycan catabolic process
is_a: GO:0006030 ! chitin metabolic process
is_a: GO:1901072 ! glucosamine-containing compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:17029 ! chitin
relationship: has_primary_input CHEBI:17029 ! chitin

[Term]
id: GO:0006040
name: amino sugar metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:jl, ISBN:0192801023]
synonym: "amino sugar metabolism" EXACT []
synonym: "aminosaccharide metabolic process" EXACT []
synonym: "aminosaccharide metabolism" EXACT []
is_a: GO:1901135 ! carbohydrate derivative metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:28963 ! amino sugar
relationship: has_primary_input_or_output CHEBI:28963 ! amino sugar

[Term]
id: GO:0006082
name: organic acid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732]
subset: goslim_pir
synonym: "organic acid metabolism" EXACT []
is_a: GO:0044237 ! cellular metabolic process
is_a: GO:0044281 ! small molecule metabolic process
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:64709 ! organic acid
relationship: has_primary_input_or_output CHEBI:64709 ! organic acid

[Term]
id: GO:0006083
name: acetate metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving acetate, the anion of acetic acid." [GOC:go_curators]
synonym: "acetate metabolism" EXACT []
is_a: GO:0032787 ! monocarboxylic acid metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:30089 ! acetate
relationship: has_primary_input_or_output CHEBI:30089 ! acetate

[Term]
id: GO:0006091
name: generation of precursor metabolites and energy
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances." [GOC:jl]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_pombe
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "energy pathways" BROAD []
synonym: "intermediary metabolism" RELATED [GOC:mah]
synonym: "metabolic energy generation" RELATED []
is_a: GO:0044237 ! cellular metabolic process

[Term]
id: GO:0006094
name: gluconeogenesis
namespace: biological_process
def: "The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [MetaCyc:GLUCONEO-PWY]
synonym: "glucose biosynthesis" EXACT []
synonym: "glucose biosynthetic process" EXACT []
xref: MetaCyc:GLUCONEO-PWY
xref: Wikipedia:Gluconeogenesis
is_a: GO:0006006 ! glucose metabolic process
is_a: GO:0019319 ! hexose biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:17234 ! glucose
relationship: has_primary_output CHEBI:17234 ! glucose

[Term]
id: GO:0006109
name: regulation of carbohydrate metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates." [GOC:go_curators]
synonym: "regulation of carbohydrate metabolism" EXACT []
is_a: GO:0080090 ! regulation of primary metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0005975 ! carbohydrate metabolic process
relationship: regulates GO:0005975 ! carbohydrate metabolic process

[Term]
id: GO:0006111
name: regulation of gluconeogenesis
namespace: biological_process
alt_id: GO:0090526
def: "Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [GOC:go_curators]
synonym: "regulation of gluconeogenesis involved in cellular glucose homeostasis" RELATED []
synonym: "regulation of glucose biosynthesis" BROAD []
synonym: "regulation of glucose biosynthetic process" BROAD []
is_a: GO:0010906 ! regulation of glucose metabolic process
is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006094 ! gluconeogenesis
relationship: regulates GO:0006094 ! gluconeogenesis
created_by: tb
creation_date: 2013-01-18T12:47:43Z

[Term]
id: GO:0006112
name: energy reserve metabolic process
namespace: biological_process
def: "The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen." [GOC:mah]
subset: goslim_pir
synonym: "energy reserve metabolism" EXACT []
is_a: GO:0015980 ! energy derivation by oxidation of organic compounds

[Term]
id: GO:0006139
name: nucleobase-containing compound metabolic process
namespace: biological_process
alt_id: GO:0055134
def: "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:ai]
subset: goslim_pir
subset: goslim_plant
synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT []
synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT []
synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED []
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb]
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT []
is_a: GO:0006725 ! cellular aromatic compound metabolic process
is_a: GO:0034641 ! cellular nitrogen compound metabolic process
is_a: GO:0044238 ! primary metabolic process
is_a: GO:0046483 ! heterocycle metabolic process
is_a: GO:1901360 ! organic cyclic compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:61120 ! nucleobase-containing molecular entity
relationship: has_primary_input_or_output CHEBI:61120 ! nucleobase-containing molecular entity

[Term]
id: GO:0006259
name: DNA metabolic process
namespace: biological_process
alt_id: GO:0055132
def: "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides." [ISBN:0198506732]
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
synonym: "cellular DNA metabolism" EXACT []
synonym: "DNA metabolism" EXACT []
is_a: GO:0090304 ! nucleic acid metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:16991 ! deoxyribonucleic acid
relationship: has_primary_input_or_output CHEBI:16991 ! deoxyribonucleic acid

[Term]
id: GO:0006308
name: DNA catabolic process
namespace: biological_process
def: "The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one." [GOC:go_curators, ISBN:0198506732]
synonym: "DNA breakdown" EXACT []
synonym: "DNA catabolism" EXACT []
synonym: "DNA degradation" EXACT []
is_a: GO:0006259 ! DNA metabolic process
is_a: GO:0009057 ! macromolecule catabolic process
is_a: GO:0034655 ! nucleobase-containing compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid
relationship: has_part GO:0004536 ! DNA nuclease activity
relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid

[Term]
id: GO:0006309
name: apoptotic DNA fragmentation
namespace: biological_process
alt_id: GO:0008178
def: "The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976, PMID:15723341, PMID:23379520]
comment: DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases. In human, these include DNA fragmentation factor (DFF) or caspase-activated DNase (CAD) and endonuclease G (Endo G) (reviewed in PMID:15723341). Caution is needed when apoptotic DNA laddering assays show presence of fragmented DNA. A positive assay may simply reflect the end point of a whole apoptotic process. Unless clear experimental evidence is available to show that a gene product is directly involved in fragmenting DNA, please do not annotate to GO:0006309 'apoptotic DNA fragmentation' and consider annotating instead to a more upstream process such as, e.g., GO:0042981 'regulation of apoptotic process', GO:0006915 'apoptotic process', GO:0097190 'apoptotic signaling pathway'. Also, note that gene products involved in compartmentalization of apoptotic nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).
synonym: "chromatinolysis" BROAD [GOC:mtg_apoptosis]
synonym: "DNA catabolic process during apoptosis" EXACT []
synonym: "DNA catabolism during apoptosis" EXACT []
synonym: "DNA fragmentation" BROAD []
synonym: "DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:cjm, GOC:dph, GOC:tb]
synonym: "endonucleolytic DNA catabolic process involved in apoptosis" EXACT []
is_a: GO:0006308 ! DNA catabolic process
intersection_of: GO:0006308 ! DNA catabolic process
intersection_of: part_of GO:0030262 ! apoptotic nuclear changes
relationship: part_of GO:0030262 ! apoptotic nuclear changes
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24396" xsd:anyURI

[Term]
id: GO:0006325
name: chromatin organization
namespace: biological_process
alt_id: GO:0006333
alt_id: GO:0006336
alt_id: GO:0016568
alt_id: GO:0031497
alt_id: GO:0034724
def: "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA." [PMID:20404130]
subset: goslim_generic
subset: goslim_pombe
subset: goslim_yeast
synonym: "chromatin assembly" NARROW []
synonym: "chromatin assembly or disassembly" RELATED []
synonym: "chromatin assembly/disassembly" RELATED []
synonym: "chromatin maintenance" BROAD []
synonym: "chromatin modification" RELATED []
synonym: "chromatin organisation" EXACT [GOC:mah]
synonym: "DNA replication-independent chromatin assembly" NARROW []
synonym: "DNA replication-independent chromatin organization" NARROW []
synonym: "DNA replication-independent nucleosome organisation" NARROW []
synonym: "DNA replication-independent nuclesome assembly" NARROW []
synonym: "establishment of chromatin architecture" EXACT [GOC:mah]
synonym: "establishment or maintenance of chromatin architecture" EXACT [GOC:mah]
synonym: "transcription-coupled nucleosome assembly" NARROW []
is_a: GO:0071824 ! protein-DNA complex organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0000785 ! chromatin
relationship: results_in_organization_of GO:0000785 ! chromatin
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22130" xsd:anyURI
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23549" xsd:anyURI

[Term]
id: GO:0006401
name: RNA catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732]
subset: goslim_yeast
synonym: "RNA breakdown" EXACT []
synonym: "RNA catabolism" EXACT []
synonym: "RNA degradation" EXACT []
is_a: GO:0009057 ! macromolecule catabolic process
is_a: GO:0016070 ! RNA metabolic process
is_a: GO:0034655 ! nucleobase-containing compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid
relationship: has_primary_input CHEBI:33697 ! ribonucleic acid

[Term]
id: GO:0006403
name: RNA localization
namespace: biological_process
def: "A process in which RNA is transported to, or maintained in, a specific location." [GOC:ai]
subset: goslim_drosophila
synonym: "establishment and maintenance of RNA localization" EXACT []
synonym: "RNA localisation" EXACT [GOC:mah]
is_a: GO:0033036 ! macromolecule localization

[Term]
id: GO:0006412
name: translation
namespace: biological_process
alt_id: GO:0006416
alt_id: GO:0006453
alt_id: GO:0043037
def: "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." [GOC:go_curators]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_prokaryote
synonym: "protein anabolism" EXACT []
synonym: "protein biosynthesis" EXACT []
synonym: "protein biosynthetic process" EXACT []
synonym: "protein formation" EXACT []
synonym: "protein synthesis" EXACT []
synonym: "protein translation" EXACT []
xref: Wikipedia:Translation_(genetics)
is_a: GO:0009059 ! macromolecule biosynthetic process
is_a: GO:0019538 ! protein metabolic process
is_a: GO:0043043 ! peptide biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:16541 ! protein polypeptide chain
intersection_of: part_of GO:0010467 ! gene expression
relationship: ends_with GO:0006415 ! translational termination
relationship: has_part GO:0006414 ! translational elongation
relationship: has_primary_output CHEBI:16541 ! protein polypeptide chain
relationship: part_of GO:0010467 ! gene expression
relationship: starts_with GO:0006413 ! translational initiation

[Term]
id: GO:0006413
name: translational initiation
namespace: biological_process
alt_id: GO:0006440
alt_id: GO:0006454
def: "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." [ISBN:019879276X]
subset: goslim_yeast
synonym: "biopolymerisation" BROAD []
synonym: "biopolymerization" BROAD []
synonym: "protein synthesis initiation" BROAD []
synonym: "translation initiation" EXACT []
is_a: GO:0044237 ! cellular metabolic process
relationship: part_of GO:0006412 ! translation
relationship: starts_with GO:0001677 ! formation of translation initiation ternary complex

[Term]
id: GO:0006414
name: translational elongation
namespace: biological_process
alt_id: GO:0006442
alt_id: GO:0006455
def: "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis." [GOC:ems]
subset: goslim_yeast
synonym: "protein synthesis elongation" BROAD []
synonym: "translation elongation" EXACT []
is_a: GO:0009059 ! macromolecule biosynthetic process
relationship: part_of GO:0006412 ! translation

[Term]
id: GO:0006415
name: translational termination
namespace: biological_process
alt_id: GO:0006443
alt_id: GO:0006456
def: "The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)." [GOC:hjd, ISBN:019879276X]
synonym: "protein synthesis termination" BROAD []
synonym: "translation termination" EXACT []
synonym: "translational complex disassembly" EXACT []
is_a: GO:0032984 ! protein-containing complex disassembly
relationship: part_of GO:0006412 ! translation

[Term]
id: GO:0006417
name: regulation of translation
namespace: biological_process
alt_id: GO:0006445
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete]
subset: goslim_yeast
synonym: "regulation of protein anabolism" EXACT []
synonym: "regulation of protein biosynthesis" EXACT []
synonym: "regulation of protein formation" EXACT []
synonym: "regulation of protein synthesis" EXACT []
is_a: GO:0010608 ! post-transcriptional regulation of gene expression
is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0051246 ! regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006412 ! translation
relationship: regulates GO:0006412 ! translation

[Term]
id: GO:0006446
name: regulation of translational initiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of translational initiation." [GOC:go_curators]
is_a: GO:0006417 ! regulation of translation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006413 ! translational initiation
relationship: regulates GO:0006413 ! translational initiation

[Term]
id: GO:0006448
name: regulation of translational elongation
namespace: biological_process
def: "Any process that modulates the frequency, rate, extent or accuracy of translational elongation." [GOC:go_curators]
is_a: GO:0006417 ! regulation of translation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006414 ! translational elongation
relationship: regulates GO:0006414 ! translational elongation

[Term]
id: GO:0006449
name: regulation of translational termination
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of translational termination." [GOC:go_curators]
is_a: GO:0006417 ! regulation of translation
is_a: GO:0043244 ! regulation of protein-containing complex disassembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006415 ! translational termination
relationship: regulates GO:0006415 ! translational termination

[Term]
id: GO:0006516
name: glycoprotein catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732]
synonym: "glycoprotein breakdown" EXACT []
synonym: "glycoprotein catabolism" EXACT []
synonym: "glycoprotein degradation" EXACT []
is_a: GO:0009057 ! macromolecule catabolic process
is_a: GO:0009100 ! glycoprotein metabolic process
is_a: GO:1901136 ! carbohydrate derivative catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:17089 ! glycoprotein
relationship: has_primary_input CHEBI:17089 ! glycoprotein

[Term]
id: GO:0006518
name: peptide metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:go_curators]
subset: goslim_pir
synonym: "peptide metabolism" EXACT []
is_a: GO:0043603 ! amide metabolic process
is_a: GO:1901564 ! organonitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:16670 ! peptide
relationship: has_primary_input_or_output CHEBI:16670 ! peptide

[Term]
id: GO:0006520
name: amino acid metabolic process
namespace: biological_process
alt_id: GO:0006519
def: "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups." [ISBN:0198506732]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pir
subset: goslim_pombe
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "amino acid and derivative metabolism" RELATED []
synonym: "cellular amino acid and derivative metabolic process" RELATED []
synonym: "cellular amino acid metabolic process" EXACT []
synonym: "cellular amino acid metabolism" EXACT []
is_a: GO:0044238 ! primary metabolic process
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:35238 ! amino acid zwitterion
relationship: has_primary_input_or_output CHEBI:35238 ! amino acid zwitterion
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI

[Term]
id: GO:0006521
name: regulation of cellular amino acid metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids." [GOC:go_curators]
synonym: "regulation of amino acid metabolism" EXACT []
is_a: GO:0010565 ! regulation of cellular ketone metabolic process
is_a: GO:0033238 ! regulation of amine metabolic process
is_a: GO:0080090 ! regulation of primary metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006520 ! amino acid metabolic process
relationship: regulates GO:0006520 ! amino acid metabolic process

[Term]
id: GO:0006576
name: biogenic amine metabolic process
namespace: biological_process
def: "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172]
synonym: "biogenic amine metabolism" EXACT []
synonym: "cellular biogenic amine metabolic process" EXACT []
is_a: GO:0009308 ! amine metabolic process

[Term]
id: GO:0006581
name: acetylcholine catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752]
synonym: "acetylcholine breakdown" EXACT []
synonym: "acetylcholine catabolism" EXACT []
synonym: "acetylcholine degradation" EXACT []
is_a: GO:0008291 ! acetylcholine metabolic process
is_a: GO:1901575 ! organic substance catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:15355 ! acetylcholine
relationship: has_primary_input CHEBI:15355 ! acetylcholine

[Term]
id: GO:0006584
name: catecholamine metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732]
synonym: "catecholamine metabolism" EXACT []
is_a: GO:0006576 ! biogenic amine metabolic process
is_a: GO:0009712 ! catechol-containing compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:33567 ! catecholamine
relationship: has_primary_input_or_output CHEBI:33567 ! catecholamine

[Term]
id: GO:0006586
name: indolalkylamine metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators]
synonym: "indolalkylamine metabolism" EXACT []
synonym: "indolamine metabolic process" BROAD []
synonym: "indolamine metabolism" BROAD []
is_a: GO:0006576 ! biogenic amine metabolic process
is_a: GO:0042430 ! indole-containing compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:38631 ! aminoalkylindole
relationship: has_primary_input_or_output CHEBI:38631 ! aminoalkylindole

[Term]
id: GO:0006629
name: lipid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." [GOC:ma]
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_pombe
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "lipid metabolism" EXACT []
xref: Wikipedia:Lipid_metabolism
is_a: GO:0044238 ! primary metabolic process
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:18059 ! lipid
relationship: has_primary_input_or_output CHEBI:18059 ! lipid

[Term]
id: GO:0006694
name: steroid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification." [GOC:go_curators]
synonym: "steroid anabolism" EXACT []
synonym: "steroid biosynthesis" EXACT []
synonym: "steroid formation" EXACT []
synonym: "steroid synthesis" EXACT []
synonym: "steroidogenesis" EXACT []
xref: Wikipedia:Steroid_metabolisms#Steroid_biosynthesis
is_a: GO:0008202 ! steroid metabolic process
is_a: GO:0008610 ! lipid biosynthetic process
is_a: GO:1901362 ! organic cyclic compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:35341 ! steroid
relationship: has_primary_output CHEBI:35341 ! steroid

[Term]
id: GO:0006699
name: bile acid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators]
synonym: "bile acid anabolism" EXACT []
synonym: "bile acid biosynthesis" EXACT []
synonym: "bile acid formation" EXACT []
synonym: "bile acid synthesis" EXACT []
is_a: GO:0006694 ! steroid biosynthetic process
is_a: GO:0008206 ! bile acid metabolic process
is_a: GO:0072330 ! monocarboxylic acid biosynthetic process
is_a: GO:1901617 ! organic hydroxy compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:36235 ! bile acid anion
relationship: has_primary_output CHEBI:36235 ! bile acid anion

[Term]
id: GO:0006706
name: steroid catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:go_curators]
synonym: "steroid breakdown" EXACT []
synonym: "steroid catabolism" EXACT []
synonym: "steroid degradation" EXACT []
is_a: GO:0008202 ! steroid metabolic process
is_a: GO:0016042 ! lipid catabolic process
is_a: GO:1901361 ! organic cyclic compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:35341 ! steroid
relationship: has_primary_input CHEBI:35341 ! steroid

[Term]
id: GO:0006725
name: cellular aromatic compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." [GOC:ai, ISBN:0198506732]
subset: goslim_pir
synonym: "aromatic compound metabolism" EXACT []
synonym: "aromatic hydrocarbon metabolic process" NARROW []
synonym: "aromatic hydrocarbon metabolism" NARROW []
is_a: GO:0044237 ! cellular metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:33655 ! aromatic compound
relationship: has_primary_input_or_output CHEBI:33655 ! aromatic compound

[Term]
id: GO:0006790
name: sulfur compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:ai]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pir
subset: goslim_pombe
subset: goslim_prokaryote
synonym: "sulfur metabolism" EXACT []
synonym: "sulphur metabolic process" EXACT []
synonym: "sulphur metabolism" EXACT []
xref: Wikipedia:Sulfur_metabolism
is_a: GO:0044237 ! cellular metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:26835 ! sulfur molecular entity
relationship: has_primary_input_or_output CHEBI:26835 ! sulfur molecular entity

[Term]
id: GO:0006793
name: phosphorus metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." [GOC:ai]
subset: goslim_pir
synonym: "phosphorus metabolism" EXACT []
is_a: GO:0044237 ! cellular metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:26082 ! phosphorus molecular entity
relationship: has_primary_input_or_output CHEBI:26082 ! phosphorus molecular entity

[Term]
id: GO:0006796
name: phosphate-containing compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." [GOC:ai]
synonym: "phosphate metabolic process" RELATED []
synonym: "phosphate metabolism" EXACT []
is_a: GO:0006793 ! phosphorus metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:26020 ! phosphate
relationship: has_primary_input_or_output CHEBI:26020 ! phosphate

[Term]
id: GO:0006807
name: nitrogen compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen." [GOC:jl, ISBN:0198506732]
subset: gocheck_do_not_annotate
subset: goslim_metagenomics
subset: goslim_pir
synonym: "nitrogen compound metabolism" EXACT []
is_a: GO:0008152 ! metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:51143 ! nitrogen molecular entity
relationship: has_primary_input_or_output CHEBI:51143 ! nitrogen molecular entity
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI

[Term]
id: GO:0006810
name: transport
namespace: biological_process
alt_id: GO:0015457
alt_id: GO:0015460
alt_id: GO:0044765
def: "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein." [GOC:dos, GOC:dph, GOC:jl, GOC:mah]
comment: Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport.
subset: gocheck_do_not_annotate
subset: goslim_candida
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_prokaryote
synonym: "single-organism transport" RELATED []
is_a: GO:0051234 ! establishment of localization
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI
created_by: jl
creation_date: 2012-12-13T16:25:32Z

[Term]
id: GO:0006811
name: monoatomic ion transport
namespace: biological_process
def: "The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:ai]
subset: goslim_drosophila
subset: goslim_pir
subset: goslim_yeast
synonym: "ion transport" BROAD []
is_a: GO:0006810 ! transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion
relationship: has_primary_input CHEBI:24867 ! monoatomic ion

[Term]
id: GO:0006812
name: monoatomic cation transport
namespace: biological_process
alt_id: GO:0006819
alt_id: GO:0015674
alt_id: GO:0072512
def: "The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." [GOC:ai]
synonym: "cation transport" BROAD []
synonym: "di-, tri-valent inorganic cation transport" NARROW [GOC:mah]
synonym: "trivalent inorganic cation transport" NARROW []
is_a: GO:0006811 ! monoatomic ion transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation
relationship: has_primary_input CHEBI:23906 ! monoatomic cation

[Term]
id: GO:0006814
name: sodium ion transport
namespace: biological_process
alt_id: GO:0006834
alt_id: GO:0016974
def: "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "mitochondrial sodium/calcium ion exchange" NARROW []
synonym: "sodium channel auxiliary protein activity" RELATED [GOC:mah]
synonym: "sodium transport" EXACT []
synonym: "sodium/potassium transport" BROAD []
synonym: "sodium:calcium exchange" NARROW []
synonym: "sodium:solute transport" NARROW []
is_a: GO:0030001 ! metal ion transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:29101 ! sodium(1+)
relationship: has_primary_input CHEBI:29101 ! sodium(1+)

[Term]
id: GO:0006817
name: phosphate ion transport
namespace: biological_process
def: "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc]
synonym: "phosphate transport" RELATED []
is_a: GO:0015698 ! inorganic anion transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:35780 ! phosphate ion
relationship: has_primary_input CHEBI:35780 ! phosphate ion

[Term]
id: GO:0006835
name: dicarboxylic acid transport
namespace: biological_process
alt_id: GO:0006841
def: "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc]
synonym: "sodium:dicarboxylate transport" RELATED []
is_a: GO:0046942 ! carboxylic acid transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:35693 ! dicarboxylic acid anion
relationship: has_primary_input CHEBI:35693 ! dicarboxylic acid anion

[Term]
id: GO:0006836
name: neurotransmitter transport
namespace: biological_process
def: "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai]
subset: goslim_pir
synonym: "sodium:neurotransmitter transport" NARROW []
is_a: GO:0006810 ! transport
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa

[Term]
id: GO:0006837
name: serotonin transport
namespace: biological_process
def: "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." [GOC:ai]
is_a: GO:0071705 ! nitrogen compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+)
relationship: has_primary_input CHEBI:350546 ! serotonin(1+)

[Term]
id: GO:0006846
name: acetate transport
namespace: biological_process
def: "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc]
is_a: GO:0015718 ! monocarboxylic acid transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:30089 ! acetate
relationship: has_primary_input CHEBI:30089 ! acetate

[Term]
id: GO:0006847
name: plasma membrane acetate transport
namespace: biological_process
def: "The directed movement of acetate across a plasma membrane." [GOC:ai]
is_a: GO:0035433 ! acetate transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:30089 ! acetate
intersection_of: results_in_transport_across GO:0005886 ! plasma membrane
relationship: results_in_transport_across GO:0005886 ! plasma membrane

[Term]
id: GO:0006858
name: extracellular transport
namespace: biological_process
def: "The transport of substances that occurs outside cells." [GOC:go_curators]
is_a: GO:0006810 ! transport
intersection_of: GO:0006810 ! transport
intersection_of: occurs_in GO:0005576 ! extracellular region
relationship: occurs_in GO:0005576 ! extracellular region

[Term]
id: GO:0006860
name: extracellular amino acid transport
namespace: biological_process
def: "The directed extracellular movement of amino acids." [GOC:ai]
is_a: GO:0006858 ! extracellular transport
is_a: GO:0006865 ! amino acid transport
intersection_of: GO:0006865 ! amino acid transport
intersection_of: occurs_in GO:0005576 ! extracellular region

[Term]
id: GO:0006865
name: amino acid transport
namespace: biological_process
alt_id: GO:0006866
def: "The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
subset: goslim_pir
subset: goslim_yeast
is_a: GO:0015849 ! organic acid transport
is_a: GO:0071705 ! nitrogen compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:33709 ! amino acid
relationship: has_primary_input CHEBI:33709 ! amino acid

[Term]
id: GO:0006869
name: lipid transport
namespace: biological_process
def: "The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [ISBN:0198506732]
subset: goslim_drosophila
subset: goslim_pir
subset: goslim_yeast
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:18059 ! lipid
relationship: has_primary_input CHEBI:18059 ! lipid
relationship: part_of GO:0010876 ! lipid localization

[Term]
id: GO:0006886
name: intracellular protein transport
namespace: biological_process
alt_id: GO:0032779
def: "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." [GOC:mah]
subset: goslim_generic
subset: goslim_prokaryote
synonym: "copper-induced intracellular protein transport" RELATED [GOC:al]
is_a: GO:0015031 ! protein transport
is_a: GO:0046907 ! intracellular transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input PR:000000001 ! protein
intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure
relationship: part_of GO:0008104 ! protein localization

[Term]
id: GO:0006887
name: exocytosis
namespace: biological_process
alt_id: GO:0016194
alt_id: GO:0016195
def: "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell." [GOC:mah, ISBN:0716731363, PMID:22323285]
subset: goslim_yeast
synonym: "nonselective vesicle exocytosis" RELATED []
synonym: "vesicle exocytosis" EXACT []
xref: Wikipedia:Exocytosis
is_a: GO:0016192 ! vesicle-mediated transport
is_a: GO:0032940 ! secretion by cell
intersection_of: GO:0006810 ! transport
intersection_of: process_has_causal_agent GO:0070382 ! exocytic vesicle
relationship: has_part GO:0099500 ! vesicle fusion to plasma membrane
relationship: process_has_causal_agent GO:0070382 ! exocytic vesicle

[Term]
id: GO:0006892
name: post-Golgi vesicle-mediated transport
namespace: biological_process
def: "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles." [GOC:ai, GOC:mah]
synonym: "post-Golgi transport" EXACT []
is_a: GO:0048193 ! Golgi vesicle transport

[Term]
id: GO:0006893
name: Golgi to plasma membrane transport
namespace: biological_process
def: "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis." [ISBN:0716731363]
synonym: "Golgi to plasma membrane vesicle-mediated transport" EXACT []
is_a: GO:0006892 ! post-Golgi vesicle-mediated transport
is_a: GO:0098876 ! vesicle-mediated transport to the plasma membrane
intersection_of: GO:0016192 ! vesicle-mediated transport
intersection_of: has_target_end_location GO:0005886 ! plasma membrane
intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus
relationship: has_target_start_location GO:0005794 ! Golgi apparatus

[Term]
id: GO:0006896
name: Golgi to vacuole transport
namespace: biological_process
def: "The directed movement of substances from the Golgi to the vacuole." [GOC:ai]
synonym: "Golgi to vacuole vesicle-mediated transport" EXACT []
is_a: GO:0006892 ! post-Golgi vesicle-mediated transport
is_a: GO:0007034 ! vacuolar transport
intersection_of: GO:0016192 ! vesicle-mediated transport
intersection_of: has_target_end_location GO:0005773 ! vacuole
intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus
intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure
relationship: has_target_end_location GO:0005773 ! vacuole
relationship: has_target_start_location GO:0005794 ! Golgi apparatus

[Term]
id: GO:0006897
name: endocytosis
namespace: biological_process
alt_id: GO:0016193
alt_id: GO:0016196
alt_id: GO:0098701
def: "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle." [GOC:mah, ISBN:0198506732, ISBN:0716731363, Wikipedia:Endocytosis]
subset: goslim_yeast
synonym: "endocytic import into cell" EXACT []
synonym: "nonselective vesicle endocytosis" RELATED []
synonym: "plasma membrane invagination" NARROW []
synonym: "vesicle endocytosis" EXACT []
xref: Wikipedia:Endocytosis
is_a: GO:0016192 ! vesicle-mediated transport
is_a: GO:0098657 ! import into cell
relationship: has_part GO:0006900 ! vesicle budding from membrane
relationship: has_part GO:0010324 ! membrane invagination
relationship: has_target_end_location GO:0031410 ! cytoplasmic vesicle
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24907" xsd:anyURI
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25268" xsd:anyURI

[Term]
id: GO:0006900
name: vesicle budding from membrane
namespace: biological_process
alt_id: GO:0006902
alt_id: GO:1902591
def: "The evagination of a membrane, resulting in formation of a vesicle." [GOC:jid, GOC:tb]
synonym: "membrane evagination" EXACT []
synonym: "nonselective vesicle assembly" RELATED []
synonym: "single organism membrane budding" RELATED [GOC:TermGenie]
synonym: "single-organism membrane budding" RELATED []
synonym: "vesicle biosynthesis" EXACT []
synonym: "vesicle budding" RELATED []
synonym: "vesicle formation" EXACT []
is_a: GO:0016050 ! vesicle organization
is_a: GO:0061024 ! membrane organization
relationship: part_of GO:0016192 ! vesicle-mediated transport
created_by: jl
creation_date: 2013-12-19T15:26:17Z

[Term]
id: GO:0006903
name: vesicle targeting
namespace: biological_process
def: "The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo." [GOC:mah, PMID:17335816]
is_a: GO:0009987 ! cellular process
relationship: part_of GO:0016192 ! vesicle-mediated transport
relationship: part_of GO:0051650 ! establishment of vesicle localization

[Term]
id: GO:0006906
name: vesicle fusion
namespace: biological_process
def: "Fusion of the membrane of a transport vesicle with its target membrane." [GOC:jid]
is_a: GO:0016050 ! vesicle organization
is_a: GO:0090174 ! organelle membrane fusion
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_fusion_of GO:0012506 ! vesicle membrane
relationship: part_of GO:0016192 ! vesicle-mediated transport
relationship: results_in_fusion_of GO:0012506 ! vesicle membrane

[Term]
id: GO:0006909
name: phagocytosis
namespace: biological_process
def: "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." [ISBN:0198506732]
xref: Wikipedia:Phagocytosis
is_a: GO:0006897 ! endocytosis
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24907" xsd:anyURI
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0006915
name: apoptotic process
namespace: biological_process
alt_id: GO:0006917
alt_id: GO:0008632
def: "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263]
synonym: "activation of apoptosis" NARROW []
synonym: "apoptosis" NARROW []
synonym: "apoptosis activator activity" RELATED []
synonym: "apoptosis signaling" NARROW []
synonym: "apoptotic cell death" EXACT [GOC:sl]
synonym: "apoptotic program" NARROW [GOC:add]
synonym: "apoptotic programmed cell death" EXACT []
synonym: "caspase-dependent programmed cell death" RELATED []
synonym: "cell suicide" BROAD []
synonym: "cellular suicide" BROAD []
synonym: "commitment to apoptosis" RELATED []
synonym: "induction of apoptosis" RELATED []
synonym: "induction of apoptosis by p53" RELATED []
synonym: "programmed cell death by apoptosis" EXACT []
synonym: "signaling (initiator) caspase activity" RELATED []
synonym: "type I programmed cell death" NARROW []
xref: Wikipedia:Apoptosis
is_a: GO:0012501 ! programmed cell death
relationship: ends_with GO:0097194 ! execution phase of apoptosis
relationship: in_taxon NCBITaxon:33154 {all_only="true"} ! Opisthokonta
relationship: only_in_taxon NCBITaxon:33154 ! Opisthokonta
relationship: starts_with GO:0097190 ! apoptotic signaling pathway
property_value: RO:0002161 NCBITaxon:2
property_value: RO:0002161 NCBITaxon:4896

[Term]
id: GO:0006921
name: cellular component disassembly involved in execution phase of apoptosis
namespace: biological_process
def: "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb]
synonym: "cellular component disassembly involved in apoptosis" NARROW []
synonym: "cellular component disassembly involved in apoptotic process" BROAD []
synonym: "disassembly of cell structures" BROAD []
is_a: GO:0022411 ! cellular component disassembly
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: part_of GO:0097194 ! execution phase of apoptosis
relationship: part_of GO:0097194 ! execution phase of apoptosis

[Term]
id: GO:0006936
name: muscle contraction
namespace: biological_process
def: "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." [GOC:ef, GOC:mtg_muscle, ISBN:0198506732]
subset: goslim_pir
xref: Wikipedia:Muscle_contraction
is_a: GO:0003012 ! muscle system process
relationship: occurs_in UBERON:0002385 ! muscle tissue

[Term]
id: GO:0006937
name: regulation of muscle contraction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of muscle contraction." [GOC:go_curators]
is_a: GO:0090257 ! regulation of muscle system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006936 ! muscle contraction
relationship: regulates GO:0006936 ! muscle contraction

[Term]
id: GO:0006939
name: smooth muscle contraction
namespace: biological_process
def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." [GOC:ef, GOC:jl, GOC:mtg_muscle, ISBN:0198506732]
synonym: "visceral muscle contraction" EXACT []
is_a: GO:0006936 ! muscle contraction
intersection_of: GO:0006936 ! muscle contraction
intersection_of: occurs_in UBERON:0001135 ! smooth muscle tissue
relationship: occurs_in UBERON:0001135 ! smooth muscle tissue

[Term]
id: GO:0006940
name: regulation of smooth muscle contraction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators]
is_a: GO:0006937 ! regulation of muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006939 ! smooth muscle contraction
relationship: regulates GO:0006939 ! smooth muscle contraction

[Term]
id: GO:0006941
name: striated muscle contraction
namespace: biological_process
def: "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope." [GOC:jl, GOC:mtg_muscle, ISBN:0198506732]
synonym: "sarcomeric muscle contraction" EXACT []
is_a: GO:0006936 ! muscle contraction
relationship: occurs_in UBERON:0002036 ! striated muscle tissue

[Term]
id: GO:0006942
name: regulation of striated muscle contraction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of striated muscle contraction." [GOC:go_curators]
is_a: GO:0006937 ! regulation of muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006941 ! striated muscle contraction
relationship: regulates GO:0006941 ! striated muscle contraction

[Term]
id: GO:0006949
name: syncytium formation
namespace: biological_process
def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division." [ISBN:0198506732]
subset: goslim_pir
is_a: GO:0009987 ! cellular process
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity CL:0000228 ! multinucleate cell
relationship: results_in_formation_of_anatomical_entity CL:0000228 ! multinucleate cell

[Term]
id: GO:0006950
name: response to stress
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_metagenomics
subset: goslim_plant
synonym: "response to abiotic stress" RELATED []
synonym: "response to biotic stress" RELATED []
is_a: GO:0050896 ! response to stimulus

[Term]
id: GO:0006952
name: defense response
namespace: biological_process
alt_id: GO:0002217
alt_id: GO:0042829
def: "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:go_curators]
synonym: "antimicrobial peptide activity" RELATED []
synonym: "defence response" EXACT []
synonym: "defense/immunity protein activity" RELATED []
synonym: "physiological defense response" EXACT []
is_a: GO:0006950 ! response to stress

[Term]
id: GO:0006954
name: inflammatory response
namespace: biological_process
def: "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages." [GO_REF:0000022, ISBN:0198506732]
subset: goslim_generic
synonym: "inflammation" BROAD []
xref: Wikipedia:Inflammation
is_a: GO:0006952 ! defense response
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>

[Term]
id: GO:0006955
name: immune response
namespace: biological_process
def: "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [GO_REF:0000022, GOC:add]
subset: goslim_drosophila
is_a: GO:0002376 ! immune system process
is_a: GO:0050896 ! response to stimulus

[Term]
id: GO:0006996
name: organelle organization
namespace: biological_process
alt_id: GO:1902589
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah]
subset: goslim_candida
subset: goslim_pir
synonym: "organelle organisation" EXACT []
synonym: "organelle organization and biogenesis" RELATED [GOC:dph, GOC:jl, GOC:mah]
synonym: "single organism organelle organization" EXACT [GOC:TermGenie]
synonym: "single-organism organelle organization" RELATED []
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0043226 ! organelle
relationship: results_in_organization_of GO:0043226 ! organelle
created_by: jl
creation_date: 2013-12-19T15:25:51Z

[Term]
id: GO:0006997
name: nucleus organization
namespace: biological_process
alt_id: GO:0048287
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." [GOC:dph, GOC:ems, GOC:jl, GOC:mah]
subset: goslim_candida
subset: goslim_drosophila
subset: goslim_pir
subset: goslim_yeast
synonym: "nuclear morphology" RELATED []
synonym: "nuclear organisation" EXACT []
synonym: "nuclear organization" EXACT []
synonym: "nuclear organization and biogenesis" RELATED [GOC:mah]
synonym: "nucleus organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0006996 ! organelle organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005634 ! nucleus
relationship: results_in_organization_of GO:0005634 ! nucleus

[Term]
id: GO:0006998
name: nuclear envelope organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." [GOC:dph, GOC:ems, GOC:jl, GOC:mah]
synonym: "nuclear envelope organisation" EXACT [GOC:mah]
synonym: "nuclear envelope organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0061024 ! membrane organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005635 ! nuclear envelope
relationship: part_of GO:0006997 ! nucleus organization
relationship: part_of GO:0010256 ! endomembrane system organization
relationship: results_in_organization_of GO:0005635 ! nuclear envelope

[Term]
id: GO:0007000
name: nucleolus organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus." [GOC:dph, GOC:jid, GOC:jl, GOC:mah]
synonym: "nucleolus organisation" EXACT []
synonym: "nucleolus organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0006997 ! nucleus organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005730 ! nucleolus
relationship: results_in_organization_of GO:0005730 ! nucleolus

[Term]
id: GO:0007009
name: plasma membrane organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." [GOC:dph, GOC:jl, GOC:mah]
subset: goslim_chembl
synonym: "plasma membrane organisation" EXACT []
synonym: "plasma membrane organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0061024 ! membrane organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005886 ! plasma membrane
relationship: part_of GO:0010256 ! endomembrane system organization
relationship: results_in_organization_of GO:0005886 ! plasma membrane

[Term]
id: GO:0007010
name: cytoskeleton organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:dph, GOC:jl, GOC:mah]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "cytoskeletal organization and biogenesis" RELATED [GOC:mah]
synonym: "cytoskeletal regulator activity" RELATED []
synonym: "cytoskeleton organisation" EXACT []
synonym: "cytoskeleton organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0006996 ! organelle organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005856 ! cytoskeleton
relationship: results_in_organization_of GO:0005856 ! cytoskeleton

[Term]
id: GO:0007015
name: actin filament organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking." [GOC:mah]
synonym: "actin filament organisation" EXACT []
synonym: "regulation of actin filament localization" NARROW []
is_a: GO:0097435 ! supramolecular fiber organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005884 ! actin filament
relationship: part_of GO:0030036 ! actin cytoskeleton organization
relationship: results_in_organization_of GO:0005884 ! actin filament

[Term]
id: GO:0007017
name: microtubule-based process
namespace: biological_process
def: "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." [GOC:mah]
subset: goslim_chembl
is_a: GO:0009987 ! cellular process
intersection_of: GO:0009987 ! cellular process
intersection_of: process_has_causal_agent GO:0005874 ! microtubule
relationship: process_has_causal_agent GO:0005874 ! microtubule
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI

[Term]
id: GO:0007018
name: microtubule-based movement
namespace: biological_process
def: "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194]
subset: goslim_drosophila
subset: goslim_generic
is_a: GO:0007017 ! microtubule-based process

[Term]
id: GO:0007019
name: microtubule depolymerization
namespace: biological_process
def: "The removal of tubulin heterodimers from one or both ends of a microtubule." [ISBN:0815316194]
synonym: "microtubule catastrophe" NARROW [GOC:dph, GOC:tb]
synonym: "microtubule depolymerization during nuclear congression" NARROW []
synonym: "microtubule disassembly" EXACT []
synonym: "microtubule shortening" EXACT []
is_a: GO:0031109 ! microtubule polymerization or depolymerization
is_a: GO:0051261 ! protein depolymerization
is_a: GO:0097435 ! supramolecular fiber organization
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0005874 ! microtubule
relationship: results_in_disassembly_of GO:0005874 ! microtubule

[Term]
id: GO:0007020
name: microtubule nucleation
namespace: biological_process
def: "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)." [GOC:go_curators, ISBN:0815316194, PMID:12517712]
xref: Wikipedia:Microtubule_nucleation
is_a: GO:0000226 ! microtubule cytoskeleton organization
relationship: part_of GO:0046785 ! microtubule polymerization

[Term]
id: GO:0007026
name: negative regulation of microtubule depolymerization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." [GOC:mah, ISBN:0815316194]
synonym: "down regulation of microtubule depolymerization" EXACT []
synonym: "down-regulation of microtubule depolymerization" EXACT []
synonym: "downregulation of microtubule depolymerization" EXACT []
synonym: "inhibition of microtubule depolymerization" NARROW []
synonym: "microtubule rescue" NARROW [GOC:dph, GOC:tb]
synonym: "microtubule stabilization" EXACT []
synonym: "negative regulation of microtubule catastrophe" NARROW [GOC:dph, GOC:tb]
synonym: "negative regulation of microtubule disassembly" EXACT []
is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization
is_a: GO:0031114 ! regulation of microtubule depolymerization
is_a: GO:1901880 ! negative regulation of protein depolymerization
is_a: GO:1902904 ! negative regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007019 ! microtubule depolymerization
relationship: negatively_regulates GO:0007019 ! microtubule depolymerization

[Term]
id: GO:0007027
name: negative regulation of axonemal microtubule depolymerization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." [GOC:dph, GOC:mah]
synonym: "axonemal microtubule stabilization" EXACT []
synonym: "negative regulation of microtubule depolymerization in axoneme" RELATED [GOC:dph]
is_a: GO:0007026 ! negative regulation of microtubule depolymerization
is_a: GO:0010937 ! regulation of cytoplasmic microtubule depolymerization
is_a: GO:0031345 ! negative regulation of cell projection organization
is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060404 ! axonemal microtubule depolymerization
relationship: negatively_regulates GO:0060404 ! axonemal microtubule depolymerization

[Term]
id: GO:0007028
name: cytoplasm organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:curators, GOC:dph, GOC:jl, GOC:mah]
subset: goslim_pir
synonym: "cytoplasm organisation" EXACT []
synonym: "cytoplasm organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005737 ! cytoplasm
relationship: results_in_organization_of GO:0005737 ! cytoplasm

[Term]
id: GO:0007030
name: Golgi organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus." [GOC:dph, GOC:jl, GOC:mah]
subset: goslim_pir
synonym: "Golgi apparatus organization" EXACT []
synonym: "Golgi organisation" EXACT []
synonym: "Golgi organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0006996 ! organelle organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005794 ! Golgi apparatus
relationship: part_of GO:0010256 ! endomembrane system organization
relationship: results_in_organization_of GO:0005794 ! Golgi apparatus

[Term]
id: GO:0007033
name: vacuole organization
namespace: biological_process
alt_id: GO:0044086
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GOC:mah]
subset: goslim_drosophila
subset: goslim_pir
subset: goslim_yeast
synonym: "vacuolar assembly" NARROW [GOC:mah]
synonym: "vacuole biogenesis" RELATED [GOC:mah]
synonym: "vacuole organisation" EXACT []
synonym: "vacuole organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0006996 ! organelle organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005773 ! vacuole
relationship: results_in_organization_of GO:0005773 ! vacuole

[Term]
id: GO:0007034
name: vacuolar transport
namespace: biological_process
def: "The directed movement of substances into, out of or within a vacuole." [GOC:ai]
subset: goslim_chembl
is_a: GO:0046907 ! intracellular transport
intersection_of: GO:0046907 ! intracellular transport
intersection_of: results_in_transport_to_from_or_in GO:0005773 ! vacuole
relationship: results_in_transport_to_from_or_in GO:0005773 ! vacuole

[Term]
id: GO:0007039
name: protein catabolic process in the vacuole
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases." [GOC:mah, GOC:vw]
synonym: "vacuolar protein breakdown" RELATED []
synonym: "vacuolar protein catabolic process" RELATED []
synonym: "vacuolar protein catabolism" RELATED []
synonym: "vacuolar protein degradation" RELATED []
is_a: GO:0030163 ! protein catabolic process
intersection_of: GO:0030163 ! protein catabolic process
intersection_of: occurs_in GO:0005773 ! vacuole
relationship: occurs_in GO:0005773 ! vacuole

[Term]
id: GO:0007043
name: cell-cell junction assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form a junction between cells." [GOC:ai]
synonym: "intercellular junction assembly" EXACT []
is_a: GO:0034329 ! cell junction assembly
is_a: GO:0045216 ! cell-cell junction organization
intersection_of: GO:0034329 ! cell junction assembly
intersection_of: results_in_assembly_of GO:0005911 ! cell-cell junction
relationship: results_in_assembly_of GO:0005911 ! cell-cell junction

[Term]
id: GO:0007049
name: cell cycle
namespace: biological_process
def: "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." [GOC:go_curators, GOC:mtg_cell_cycle]
subset: gocheck_do_not_manually_annotate
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_pir
subset: goslim_plant
synonym: "cell-division cycle" EXACT []
xref: Wikipedia:Cell_cycle
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0007059
name: chromosome segregation
namespace: biological_process
def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:jl, GOC:mah, GOC:mtg_cell_cycle, GOC:vw]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pir
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "chromosome division" EXACT []
synonym: "chromosome transmission" RELATED []
xref: Wikipedia:Chromosome_segregation
is_a: GO:0022402 ! cell cycle process

[Term]
id: GO:0007076
name: mitotic chromosome condensation
namespace: biological_process
def: "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells." [GOC:mah, ISBN:0815316194]
is_a: GO:0030261 ! chromosome condensation
is_a: GO:1903047 ! mitotic cell cycle process
intersection_of: GO:0030261 ! chromosome condensation
intersection_of: part_of GO:0000278 ! mitotic cell cycle
relationship: part_of GO:0000070 ! mitotic sister chromatid segregation

[Term]
id: GO:0007077
name: mitotic nuclear membrane disassembly
namespace: biological_process
def: "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis." [GOC:bf, PMID:32848252]
synonym: "local NEB" BROAD []
synonym: "mitotic nuclear envelope breakdown" EXACT []
synonym: "mitotic nuclear envelope catabolism" RELATED []
synonym: "mitotic nuclear envelope degradation" RELATED []
synonym: "mitotic nuclear envelope disassembly" RELATED []
synonym: "NEB" BROAD []
synonym: "nuclear envelope breakdown" BROAD []
is_a: GO:0051081 ! nuclear membrane disassembly
is_a: GO:1903047 ! mitotic cell cycle process
intersection_of: GO:0051081 ! nuclear membrane disassembly
intersection_of: part_of GO:0000278 ! mitotic cell cycle

[Term]
id: GO:0007088
name: regulation of mitotic nuclear division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mitosis." [GOC:go_curators]
synonym: "regulation of mitosis" EXACT []
is_a: GO:0007346 ! regulation of mitotic cell cycle
is_a: GO:0010564 ! regulation of cell cycle process
is_a: GO:0051783 ! regulation of nuclear division
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0140014 ! mitotic nuclear division
relationship: regulates GO:0140014 ! mitotic nuclear division

[Term]
id: GO:0007097
name: nuclear migration
namespace: biological_process
alt_id: GO:0040023
def: "The directed movement of the nucleus to a specific location within a cell." [GOC:ai]
synonym: "establishment of cell nucleus localization" RELATED []
synonym: "establishment of localization of nucleus" RELATED []
synonym: "establishment of nucleus localisation" RELATED [GOC:mah]
synonym: "establishment of nucleus localization" RELATED []
synonym: "establishment of position of nucleus" EXACT []
synonym: "nuclear movement" EXACT []
synonym: "nuclear positioning" EXACT []
synonym: "nucleus migration" EXACT []
synonym: "nucleus positioning" EXACT []
synonym: "positioning of nucleus" EXACT []
is_a: GO:0046907 ! intracellular transport
is_a: GO:0051647 ! nucleus localization
is_a: GO:0051656 ! establishment of organelle localization
intersection_of: GO:0046907 ! intracellular transport
intersection_of: has_primary_input GO:0005634 ! nucleus

[Term]
id: GO:0007113
name: endomitotic cell cycle
namespace: biological_process
def: "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell." [GOC:curators, GOC:dos, GOC:expert_vm]
comment: Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins.
synonym: "endomitosis" RELATED []
xref: Wikipedia:Mitosis#Endomitosis
is_a: GO:0000278 ! mitotic cell cycle

[Term]
id: GO:0007135
name: meiosis II
namespace: biological_process
def: "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II." [GOC:dph, GOC:mah, ISBN:0198547684]
synonym: "meiosis II nuclear division" EXACT []
xref: Wikipedia:Meiosis#Meiosis_II
is_a: GO:0061983 ! meiosis II cell cycle process
is_a: GO:0140013 ! meiotic nuclear division

[Term]
id: GO:0007140
name: male meiotic nuclear division
namespace: biological_process
def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline." [GOC:dph, GOC:mah, GOC:vw]
synonym: "male meiosis" RELATED []
synonym: "male nuclear division" BROAD []
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0140013 ! meiotic nuclear division
intersection_of: GO:0000280 ! nuclear division
intersection_of: part_of GO:0048232 ! male gamete generation
intersection_of: part_of GO:0051321 ! meiotic cell cycle
relationship: part_of GO:0048232 ! male gamete generation
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0007142
name: male meiosis II
namespace: biological_process
def: "A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline." [GOC:dph, GOC:mah]
synonym: "male meiosis II nuclear division" EXACT []
is_a: GO:0007135 ! meiosis II
is_a: GO:0007140 ! male meiotic nuclear division
intersection_of: GO:0007135 ! meiosis II
intersection_of: part_of GO:0048232 ! male gamete generation
intersection_of: part_of GO:0051321 ! meiotic cell cycle

[Term]
id: GO:0007143
name: female meiotic nuclear division
namespace: biological_process
def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline." [GOC:dph, GOC:ems, GOC:mah, GOC:vw]
comment: Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'.
synonym: "female meiosis" BROAD []
synonym: "female meiotic division" BROAD []
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0140013 ! meiotic nuclear division
intersection_of: GO:0000280 ! nuclear division
intersection_of: part_of GO:0007292 ! female gamete generation
intersection_of: part_of GO:0051321 ! meiotic cell cycle
relationship: part_of GO:0007292 ! female gamete generation
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0007147
name: female meiosis II
namespace: biological_process
def: "The cell cycle process in which the second meiotic division occurs in the female germline." [GOC:mah]
synonym: "female meiosis II nuclear division" EXACT []
is_a: GO:0007135 ! meiosis II
is_a: GO:0007143 ! female meiotic nuclear division
intersection_of: GO:0007135 ! meiosis II
intersection_of: part_of GO:0007292 ! female gamete generation
intersection_of: part_of GO:0051321 ! meiotic cell cycle

[Term]
id: GO:0007154
name: cell communication
namespace: biological_process
def: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah]
subset: goslim_pir
subset: goslim_plant
xref: Wikipedia:Cell_signaling
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0007155
name: cell adhesion
namespace: biological_process
alt_id: GO:0098602
def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." [GOC:hb, GOC:pf]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_pombe
subset: goslim_prokaryote
synonym: "cell adhesion molecule activity" RELATED []
synonym: "single organism cell adhesion" RELATED []
xref: Wikipedia:Cell_adhesion
is_a: GO:0009987 ! cellular process
created_by: dos
creation_date: 2014-04-15T15:59:10Z

[Term]
id: GO:0007159
name: leukocyte cell-cell adhesion
namespace: biological_process
def: "The attachment of a leukocyte to another cell via adhesion molecules." [GOC:go_curators]
synonym: "leukocyte adhesion" EXACT []
synonym: "leukocyte cell adhesion" EXACT []
is_a: GO:0098609 ! cell-cell adhesion
intersection_of: GO:0098609 ! cell-cell adhesion
intersection_of: has_participant CL:0000738 ! leukocyte
relationship: has_participant CL:0000738 ! leukocyte
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>

[Term]
id: GO:0007162
name: negative regulation of cell adhesion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion." [GOC:go_curators]
synonym: "cell adhesion receptor inhibitor activity" RELATED []
synonym: "down regulation of cell adhesion" EXACT []
synonym: "down-regulation of cell adhesion" EXACT []
synonym: "downregulation of cell adhesion" EXACT []
synonym: "inhibition of cell adhesion" NARROW []
is_a: GO:0030155 ! regulation of cell adhesion
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007155 ! cell adhesion
relationship: negatively_regulates GO:0007155 ! cell adhesion

[Term]
id: GO:0007163
name: establishment or maintenance of cell polarity
namespace: biological_process
alt_id: GO:0030012
alt_id: GO:0030467
def: "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah]
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pombe
subset: goslim_prokaryote
synonym: "cell polarity" RELATED [GOC:mah, GOC:vw]
synonym: "establishment and/or maintenance of cell polarity" RELATED []
synonym: "establishment and/or maintenance of cell polarization" RELATED []
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0007165
name: signal transduction
namespace: biological_process
alt_id: GO:0023014
alt_id: GO:0023015
alt_id: GO:0023016
alt_id: GO:0023033
alt_id: GO:0023045
def: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11]
comment: Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.
subset: goslim_candida
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_plant
synonym: "signal transduction by cis-phosphorylation" NARROW []
synonym: "signal transduction by conformational transition" NARROW []
synonym: "signal transduction by protein phosphorylation" NARROW []
synonym: "signal transduction by trans-phosphorylation" NARROW []
synonym: "signaling cascade" NARROW []
synonym: "signaling pathway" RELATED []
synonym: "signalling cascade" NARROW []
synonym: "signalling pathway" RELATED [GOC:mah]
xref: Wikipedia:Signal_transduction
is_a: GO:0009987 ! cellular process
is_a: GO:0050794 ! regulation of cellular process
relationship: part_of GO:0007154 ! cell communication
relationship: part_of GO:0023052 ! signaling
relationship: part_of GO:0051716 ! cellular response to stimulus

[Term]
id: GO:0007267
name: cell-cell signaling
namespace: biological_process
def: "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." [GOC:dos, GOC:mah]
subset: goslim_chembl
subset: goslim_plant
synonym: "cell-cell signalling" EXACT []
is_a: GO:0007154 ! cell communication
is_a: GO:0023052 ! signaling

[Term]
id: GO:0007268
name: chemical synaptic transmission
namespace: biological_process
def: "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:jl, MeSH:D009435]
subset: goslim_synapse
synonym: "neurotransmission" RELATED [GOC:dph]
synonym: "signal transmission across a synapse" BROAD []
synonym: "synaptic transmission" BROAD []
xref: Wikipedia:Neurotransmission
is_a: GO:0098916 ! anterograde trans-synaptic signaling
relationship: has_participant GO:0045202 ! synapse

[Term]
id: GO:0007269
name: neurotransmitter secretion
namespace: biological_process
alt_id: GO:0010554
def: "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission." [GOC:dph]
comment: A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
subset: goslim_synapse
synonym: "neurotransmitter release" EXACT []
synonym: "neurotransmitter secretory pathway" EXACT []
is_a: GO:0006836 ! neurotransmitter transport
is_a: GO:0051649 ! establishment of localization in cell
is_a: GO:0099643 ! signal release from synapse
relationship: occurs_in GO:0098793 ! presynapse

[Term]
id: GO:0007271
name: synaptic transmission, cholinergic
namespace: biological_process
def: "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, Wikipedia:Cholinergic]
synonym: "cholinergic synaptic transmission" EXACT []
is_a: GO:0007268 ! chemical synaptic transmission
relationship: has_participant CHEBI:15355 ! acetylcholine

[Term]
id: GO:0007274
name: neuromuscular synaptic transmission
namespace: biological_process
def: "The process of synaptic transmission from a neuron to a muscle, across a synapse." [GOC:dos, GOC:jl, MeSH:D009435]
is_a: GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0007275
name: multicellular organism development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb]
comment: Note that this term was 'developmental process'.
subset: gocheck_do_not_annotate
subset: goslim_chembl
subset: goslim_plant
is_a: GO:0032501 ! multicellular organismal process
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_developmental_progression_of UBERON:0000468 ! multicellular organism
relationship: results_in_developmental_progression_of UBERON:0000468 ! multicellular organism
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21234" xsd:anyURI

[Term]
id: GO:0007276
name: gamete generation
namespace: biological_process
alt_id: GO:0009552
def: "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." [GOC:ems, GOC:mtg_sensu]
synonym: "gametogenesis" RELATED []
is_a: GO:0048609 ! multicellular organismal reproductive process
relationship: part_of GO:0019953 ! sexual reproduction
property_value: RO:0002161 NCBITaxon_Union:0000023

[Term]
id: GO:0007281
name: germ cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." [GOC:go_curators]
synonym: "gametogenesis" NARROW []
synonym: "germ-cell development" EXACT []
synonym: "primordial germ cell development" NARROW []
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000586 ! germ cell
relationship: part_of GO:0007276 ! gamete generation
relationship: results_in_development_of CL:0000586 ! germ cell

[Term]
id: GO:0007283
name: spermatogenesis
namespace: biological_process
def: "The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa." [GOC:jid, ISBN:9780878933846, PMID:28073824, PMID:30990821]
synonym: "generation of spermatozoa" EXACT systematic_synonym []
xref: Wikipedia:Spermatogenesis
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0048232 ! male gamete generation

[Term]
id: GO:0007284
name: spermatogonial cell division
namespace: biological_process
def: "The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes)." [GOC:bf, GOC:pr, ISBN:0879694238]
comment: See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'.
synonym: "spermatogonium division" EXACT []
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0051301 ! cell division
intersection_of: GO:0051301 ! cell division
intersection_of: has_primary_input CL:0000020 ! spermatogonium
relationship: has_primary_input CL:0000020 ! spermatogonium
relationship: part_of GO:0007283 ! spermatogenesis

[Term]
id: GO:0007285
name: primary spermatocyte growth
namespace: biological_process
def: "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis." [GOC:jid, ISBN:0879694238]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0048588 ! developmental cell growth
intersection_of: GO:0040007 ! growth
intersection_of: results_in_growth_of CL:0000656 ! primary spermatocyte
relationship: part_of GO:0007283 ! spermatogenesis
relationship: results_in_growth_of CL:0000656 ! primary spermatocyte

[Term]
id: GO:0007286
name: spermatid development
namespace: biological_process
def: "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure." [GOC:dph, GOC:go_curators]
synonym: "spermatid cell development" EXACT []
synonym: "spermiogenesis" EXACT []
xref: Wikipedia:Spermiogenesis
is_a: GO:0007281 ! germ cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000018 ! spermatid
relationship: part_of GO:0048515 ! spermatid differentiation
relationship: results_in_development_of CL:0000018 ! spermatid

[Term]
id: GO:0007288
name: sperm axoneme assembly
namespace: biological_process
def: "The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement." [GOC:bf, GOC:cilia, ISBN:0198547684]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0035082 ! axoneme assembly
intersection_of: GO:0035082 ! axoneme assembly
intersection_of: occurs_in CL:0000019 ! sperm
relationship: occurs_in CL:0000019 ! sperm
relationship: part_of GO:0120316 ! sperm flagellum assembly

[Term]
id: GO:0007289
name: spermatid nucleus differentiation
namespace: biological_process
def: "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization." [GOC:bf, GOC:dph, GOC:jl, GOC:mah]
comment: See also the Cell Ontology term 'spermatid ; CL:0000018'.
synonym: "spermatid nuclear differentiation" EXACT []
is_a: GO:0006997 ! nucleus organization
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
relationship: part_of GO:0007286 ! spermatid development

[Term]
id: GO:0007292
name: female gamete generation
namespace: biological_process
def: "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction." [GOC:dph, ISBN:0198506732]
is_a: GO:0007276 ! gamete generation

[Term]
id: GO:0007293
name: germarium-derived egg chamber formation
namespace: biological_process
def: "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda
relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda
relationship: part_of GO:0048477 ! oogenesis

[Term]
id: GO:0007308
name: oocyte construction
namespace: biological_process
alt_id: GO:0048110
def: "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:ems, GOC:mtg_sensu, GOC:tb, ISBN:0198506732]
synonym: "oocyte arrangement" EXACT [GOC:dph, GOC:tb]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0048469 ! cell maturation
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_formation_of_anatomical_entity CL:0000023 ! oocyte
relationship: part_of GO:0048599 ! oocyte development
relationship: results_in_formation_of_anatomical_entity CL:0000023 ! oocyte

[Term]
id: GO:0007309
name: oocyte axis specification
namespace: biological_process
alt_id: GO:0048111
def: "The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238]
synonym: "oocyte axis determination" RELATED []
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0009798 ! axis specification
intersection_of: GO:0009798 ! axis specification
intersection_of: occurs_in CL:0000023 ! oocyte
relationship: occurs_in CL:0000023 ! oocyte
relationship: part_of GO:0007308 ! oocyte construction

[Term]
id: GO:0007314
name: oocyte anterior/posterior axis specification
namespace: biological_process
alt_id: GO:0048112
def: "Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238]
synonym: "oocyte anterior/posterior axis determination" EXACT [GOC:dph, GOC:tb]
is_a: GO:0007309 ! oocyte axis specification
is_a: GO:0009948 ! anterior/posterior axis specification
intersection_of: GO:0009948 ! anterior/posterior axis specification
intersection_of: occurs_in CL:0000023 ! oocyte
relationship: part_of GO:0008358 ! maternal determination of anterior/posterior axis, embryo

[Term]
id: GO:0007320
name: insemination
namespace: biological_process
def: "The introduction of semen or sperm into the genital tract of a female." [ISBN:0582227089]
xref: Wikipedia:Insemination
is_a: GO:0044703 ! multi-organism reproductive process
is_a: GO:0044706 ! multi-multicellular organism process
is_a: GO:0048609 ! multicellular organismal reproductive process
relationship: part_of GO:0007620 ! copulation

[Term]
id: GO:0007338
name: single fertilization
namespace: biological_process
def: "The union of male and female gametes to form a zygote." [GOC:ems, GOC:mtg_sensu]
synonym: "zygote biosynthesis" RELATED []
synonym: "zygote formation" RELATED []
is_a: GO:0009566 ! fertilization
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
property_value: RO:0002161 NCBITaxon:58024

[Term]
id: GO:0007343
name: egg activation
namespace: biological_process
def: "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm." [GOC:bf, PMID:9630751]
xref: Wikipedia:Egg_activation
is_a: GO:0001775 ! cell activation
is_a: GO:0022414 ! reproductive process
intersection_of: GO:0001775 ! cell activation
intersection_of: has_primary_input CL:0000025 ! egg cell
relationship: has_primary_input CL:0000025 ! egg cell
relationship: part_of GO:0007338 ! single fertilization

[Term]
id: GO:0007346
name: regulation of mitotic cell cycle
namespace: biological_process
def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "mitotic cell cycle modulation" EXACT []
synonym: "mitotic cell cycle regulation" EXACT []
synonym: "mitotic cell cycle regulator" RELATED []
synonym: "modulation of mitotic cell cycle progression" EXACT []
synonym: "regulation of mitotic cell cycle progression" EXACT []
synonym: "regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb]
is_a: GO:0051726 ! regulation of cell cycle
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0000278 ! mitotic cell cycle
relationship: regulates GO:0000278 ! mitotic cell cycle

[Term]
id: GO:0007350
name: blastoderm segmentation
namespace: biological_process
def: "The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]
is_a: GO:0009880 ! embryonic pattern specification
is_a: GO:0035282 ! segmentation

[Term]
id: GO:0007351
name: tripartite regional subdivision
namespace: biological_process
def: "Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions." [GOC:dph, GOC:isa_complete, http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]
is_a: GO:0003002 ! regionalization
relationship: part_of GO:0007350 ! blastoderm segmentation

[Term]
id: GO:0007354
name: zygotic determination of anterior/posterior axis, embryo
namespace: biological_process
def: "The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]
is_a: GO:0008595 ! anterior/posterior axis specification, embryo
intersection_of: GO:0008595 ! anterior/posterior axis specification, embryo
intersection_of: occurs_in CL:0000365 ! animal zygote
relationship: occurs_in CL:0000365 ! animal zygote

[Term]
id: GO:0007369
name: gastrulation
namespace: biological_process
def: "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:curators, ISBN:9780878933846]
subset: goslim_drosophila
xref: Wikipedia:Gastrulation
is_a: GO:0048598 ! embryonic morphogenesis
relationship: has_part GO:0001705 ! ectoderm formation
relationship: has_part GO:0001706 ! endoderm formation
relationship: has_part GO:0001707 ! mesoderm formation

[Term]
id: GO:0007389
name: pattern specification process
namespace: biological_process
def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate." [GOC:go_curators, GOC:isa_complete, ISBN:0521436125]
subset: goslim_drosophila
synonym: "pattern biosynthesis" RELATED []
synonym: "pattern formation" RELATED []
is_a: GO:0032501 ! multicellular organismal process
relationship: part_of GO:0007275 ! multicellular organism development

[Term]
id: GO:0007398
name: ectoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." [GOC:dph, GOC:tb]
is_a: GO:0009888 ! tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000924 ! ectoderm
relationship: results_in_development_of UBERON:0000924 ! ectoderm

[Term]
id: GO:0007399
name: nervous system development
namespace: biological_process
def: "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." [GOC:dgh]
subset: goslim_drosophila
synonym: "pan-neural process" RELATED []
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001016 ! nervous system
relationship: results_in_development_of UBERON:0001016 ! nervous system

[Term]
id: GO:0007405
name: neuroblast proliferation
namespace: biological_process
alt_id: GO:0043349
alt_id: GO:0043350
def: "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron." [GOC:ai, GOC:mtg_sensu, GOC:sart]
is_a: GO:0061351 ! neural precursor cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: acts_on_population_of CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of GO:0048699 ! generation of neurons

[Term]
id: GO:0007406
name: negative regulation of neuroblast proliferation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts." [GOC:ai]
synonym: "down regulation of neuroblast proliferation" EXACT []
synonym: "down-regulation of neuroblast proliferation" EXACT []
synonym: "downregulation of neuroblast proliferation" EXACT []
synonym: "inhibition of neuroblast proliferation" NARROW []
synonym: "suppression of neuroblast proliferation" EXACT []
is_a: GO:0050768 ! negative regulation of neurogenesis
is_a: GO:1902692 ! regulation of neuroblast proliferation
is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007405 ! neuroblast proliferation
relationship: negatively_regulates GO:0007405 ! neuroblast proliferation

[Term]
id: GO:0007407
name: neuroblast activation
namespace: biological_process
alt_id: GO:0043351
alt_id: GO:0043352
def: "A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:go_curators, GOC:mtg_sensu]
is_a: GO:0001775 ! cell activation
intersection_of: GO:0001775 ! cell activation
intersection_of: has_primary_input CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: has_primary_input CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: part_of GO:0048699 ! generation of neurons

[Term]
id: GO:0007416
name: synapse assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)." [GOC:mah]
subset: goslim_synapse
synonym: "synapse biogenesis" EXACT [GOC:mah]
synonym: "synaptogenesis" EXACT [GOC:mah]
xref: Wikipedia:Synaptogenesis
is_a: GO:0034329 ! cell junction assembly
is_a: GO:0050808 ! synapse organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_assembly_of GO:0045202 ! synapse
relationship: part_of GO:0007399 ! nervous system development
relationship: results_in_assembly_of GO:0045202 ! synapse

[Term]
id: GO:0007417
name: central nervous system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GOC:bf, GOC:jid, ISBN:0582227089]
synonym: "CNS development" EXACT []
xref: Wikipedia:Neural_development
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001017 ! central nervous system
relationship: part_of GO:0007399 ! nervous system development
relationship: results_in_development_of UBERON:0001017 ! central nervous system

[Term]
id: GO:0007420
name: brain development
namespace: biological_process
def: "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dph, GOC:jid, GOC:tb, UBERON:0000955]
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000955 ! brain
relationship: part_of GO:0007417 ! central nervous system development
relationship: part_of GO:0060322 ! head development
relationship: results_in_development_of UBERON:0000955 ! brain

[Term]
id: GO:0007422
name: peripheral nervous system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GOC:go_curators, UBERON:0000010]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000010 ! peripheral nervous system
relationship: part_of GO:0007399 ! nervous system development
relationship: results_in_development_of UBERON:0000010 ! peripheral nervous system

[Term]
id: GO:0007423
name: sensory organ development
namespace: biological_process
def: "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." [GOC:go_curators]
subset: goslim_drosophila
synonym: "sense organ development" EXACT [GOC:dph]
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000020 ! sense organ
relationship: results_in_development_of UBERON:0000020 ! sense organ

[Term]
id: GO:0007439
name: ectodermal digestive tract development
namespace: biological_process
def: "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm." [GOC:curators]
synonym: "ectodermal gut development" RELATED [GOC:dph]
is_a: GO:0048729 ! tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0004906 ! ectodermal part of digestive tract
relationship: part_of GO:0048565 ! digestive tract development
relationship: results_in_formation_of_anatomical_entity UBERON:0004906 ! ectodermal part of digestive tract

[Term]
id: GO:0007440
name: foregut morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the foregut are generated and organized." [GOC:jid]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001041 ! foregut
relationship: part_of GO:0048546 ! digestive tract morphogenesis
relationship: results_in_morphogenesis_of UBERON:0001041 ! foregut

[Term]
id: GO:0007442
name: hindgut morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the hindgut are generated and organized." [GOC:jid]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001046 ! hindgut
relationship: part_of GO:0048546 ! digestive tract morphogenesis
relationship: part_of GO:0061525 ! hindgut development
relationship: results_in_morphogenesis_of UBERON:0001046 ! hindgut

[Term]
id: GO:0007492
name: endoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." [GOC:dph, GOC:tb]
is_a: GO:0009888 ! tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000925 ! endoderm
relationship: results_in_development_of UBERON:0000925 ! endoderm

[Term]
id: GO:0007494
name: midgut development
namespace: biological_process
def: "The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine." [GOC:jid, UBERON:0001045]
is_a: GO:0048565 ! digestive tract development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001045 ! midgut
relationship: results_in_development_of UBERON:0001045 ! midgut

[Term]
id: GO:0007498
name: mesoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb]
subset: goslim_drosophila
is_a: GO:0009888 ! tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000926 ! mesoderm
relationship: results_in_development_of UBERON:0000926 ! mesoderm

[Term]
id: GO:0007506
name: gonadal mesoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism." [GOC:ai]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0007498 ! mesoderm development
is_a: GO:0060485 ! mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003855 ! gonad mesenchyme
relationship: part_of GO:0008406 ! gonad development
relationship: results_in_development_of UBERON:0003855 ! gonad mesenchyme

[Term]
id: GO:0007507
name: heart development
namespace: biological_process
alt_id: GO:0007511
def: "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:jid, UBERON:0000948]
synonym: "cardiac development" RELATED []
synonym: "dorsal vessel development" NARROW []
xref: Wikipedia:Heart_development
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0007100 ! primary circulatory organ
relationship: part_of GO:0072359 ! circulatory system development
relationship: results_in_development_of UBERON:0007100 ! primary circulatory organ

[Term]
id: GO:0007517
name: muscle organ development
namespace: biological_process
def: "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." [GOC:jid, ISBN:0198506732]
is_a: GO:0048513 ! animal organ development
is_a: GO:0061061 ! muscle structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001630 ! muscle organ
relationship: results_in_development_of UBERON:0001630 ! muscle organ

[Term]
id: GO:0007519
name: skeletal muscle tissue development
namespace: biological_process
alt_id: GO:0048637
def: "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers." [GOC:mtg_muscle]
synonym: "myogenesis" RELATED []
is_a: GO:0014706 ! striated muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001134 ! skeletal muscle tissue
relationship: part_of GO:0060538 ! skeletal muscle organ development
relationship: results_in_development_of UBERON:0001134 ! skeletal muscle tissue

[Term]
id: GO:0007525
name: somatic muscle development
namespace: biological_process
def: "The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle." [GOC:jid, GOC:mtg_muscle]
is_a: GO:0061061 ! muscle structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0014895 ! somatic muscle
relationship: results_in_development_of UBERON:0014895 ! somatic muscle

[Term]
id: GO:0007528
name: neuromuscular junction development
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction." [GOC:mtg_OBO2OWL_2013]
synonym: "neuromuscular junction organization" EXACT []
synonym: "neuromuscular junction stability" RELATED [GOC:pr]
synonym: "NMJ stability" RELATED [GOC:pr]
is_a: GO:0050808 ! synapse organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0031594 ! neuromuscular junction
relationship: results_in_organization_of GO:0031594 ! neuromuscular junction

[Term]
id: GO:0007548
name: sex differentiation
namespace: biological_process
def: "The establishment of the sex of an organism by physical differentiation." [GOC:ai]
xref: Wikipedia:Sexual_differentiation
is_a: GO:0003006 ! developmental process involved in reproduction

[Term]
id: GO:0007565
name: female pregnancy
namespace: biological_process
def: "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth." [ISBN:0192800825]
subset: goslim_chembl
synonym: "carrying of young" RELATED []
synonym: "gestation" EXACT []
xref: Wikipedia:Gestation
is_a: GO:0044703 ! multi-organism reproductive process
is_a: GO:0044706 ! multi-multicellular organism process
relationship: in_taxon NCBITaxon:40674 {all_only="true"} ! Mammalia
relationship: only_in_taxon NCBITaxon:40674 ! Mammalia

[Term]
id: GO:0007566
name: embryo implantation
namespace: biological_process
def: "Attachment of the blastocyst to the uterine lining." [GOC:isa_complete, http://www.medterms.com]
synonym: "blastocyst implantation" EXACT []
is_a: GO:0022414 ! reproductive process
relationship: part_of GO:0007275 ! multicellular organism development
relationship: part_of GO:0007565 ! female pregnancy

[Term]
id: GO:0007585
name: respiratory gaseous exchange by respiratory system
namespace: biological_process
def: "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [ISBN:0198506732]
subset: goslim_chembl
synonym: "breathing" BROAD []
synonym: "respiration" BROAD []
is_a: GO:0032501 ! multicellular organismal process

[Term]
id: GO:0007586
name: digestion
namespace: biological_process
def: "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, ISBN:0198506732]
subset: goslim_chembl
subset: goslim_pir
xref: Wikipedia:Digestion
is_a: GO:0032501 ! multicellular organismal process

[Term]
id: GO:0007588
name: excretion
namespace: biological_process
def: "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds." [ISBN:0192801023]
subset: gocheck_do_not_annotate
subset: goslim_pir
xref: Wikipedia:Excretion
is_a: GO:0003008 ! system process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI

[Term]
id: GO:0007589
name: body fluid secretion
namespace: biological_process
def: "The controlled release of a fluid by a cell or tissue in an animal." [GOC:ai, GOC:dph, GOC:mah, GOC:tb]
is_a: GO:0046903 ! secretion
is_a: GO:0050878 ! regulation of body fluid levels

[Term]
id: GO:0007600
name: sensory perception
namespace: biological_process
def: "The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai, GOC:dph]
subset: goslim_drosophila
xref: Wikipedia:Perception
is_a: GO:0050877 ! nervous system process

[Term]
id: GO:0007601
name: visual perception
namespace: biological_process
def: "The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image." [GOC:ai]
synonym: "sense of sight" EXACT []
synonym: "sensory visual perception" EXACT []
synonym: "vision" EXACT []
xref: Wikipedia:Visual_perception
is_a: GO:0050953 ! sensory perception of light stimulus

[Term]
id: GO:0007605
name: sensory perception of sound
namespace: biological_process
def: "The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound." [GOC:ai]
synonym: "hearing" EXACT []
synonym: "perception of sound" EXACT []
xref: Wikipedia:Hearing_(sense)
is_a: GO:0050954 ! sensory perception of mechanical stimulus

[Term]
id: GO:0007606
name: sensory perception of chemical stimulus
namespace: biological_process
def: "The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai]
synonym: "chemosensory perception" EXACT []
is_a: GO:0007600 ! sensory perception

[Term]
id: GO:0007610
name: behavior
namespace: biological_process
alt_id: GO:0023032
alt_id: GO:0044708
alt_id: GO:0044709
def: "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973]
comment: 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews.\n2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis).
subset: gocheck_do_not_manually_annotate
subset: goslim_agr
subset: goslim_flybase_ribbon
synonym: "behavioral response to stimulus" EXACT []
synonym: "behaviour" EXACT []
synonym: "behavioural response to stimulus" EXACT []
synonym: "single-organism behavior" RELATED []
xref: Wikipedia:Behavior
is_a: GO:0032501 ! multicellular organismal process
disjoint_from: GO:0032502 ! developmental process
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: process_has_causal_agent UBERON:0001016 ! nervous system
created_by: jl
creation_date: 2012-09-20T14:06:08Z

[Term]
id: GO:0007617
name: mating behavior
namespace: biological_process
def: "The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes." [GOC:ai, GOC:dph]
synonym: "mating behaviour" EXACT []
xref: Wikipedia:Mating_behaviour
is_a: GO:0019098 ! reproductive behavior

[Term]
id: GO:0007620
name: copulation
namespace: biological_process
def: "The act of sexual union between male and female, involving the transfer of sperm." [ISBN:0721662544]
is_a: GO:0007617 ! mating behavior

[Term]
id: GO:0007626
name: locomotory behavior
namespace: biological_process
def: "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." [GOC:dph]
subset: goslim_drosophila
synonym: "behavior via locomotion" EXACT []
synonym: "locomotion in response to stimulus" EXACT []
synonym: "locomotory behavioral response to stimulus" EXACT []
synonym: "locomotory behaviour" EXACT []
synonym: "locomotory behavioural response to stimulus" EXACT []
is_a: GO:0007610 ! behavior

[Term]
id: GO:0008015
name: blood circulation
namespace: biological_process
alt_id: GO:0070261
def: "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products." [GOC:mtg_heart, ISBN:0192800825]
subset: goslim_pir
synonym: "hemolymph circulation" RELATED []
is_a: GO:0003013 ! circulatory system process

[Term]
id: GO:0008016
name: regulation of heart contraction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "regulation of cardiac contraction" EXACT []
is_a: GO:1903522 ! regulation of blood circulation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060047 ! heart contraction
relationship: regulates GO:0060047 ! heart contraction

[Term]
id: GO:0008028
name: monocarboxylic acid transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0008505
def: "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." [GOC:ai]
synonym: "monocarboxylate carrier" NARROW []
synonym: "prostaglandin/thromboxane transporter activity" NARROW []
xref: Reactome:R-HSA-429749 "SLC5A8 transports monocarboxylates from extracellular region to cytosol"
xref: Reactome:R-HSA-433698 "SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol"
xref: Reactome:R-HSA-5624211 "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol"
xref: Reactome:R-HSA-9645220 "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol"
is_a: GO:0005342 ! organic acid transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:25384 ! monocarboxylic acid
relationship: has_primary_input CHEBI:25384 ! monocarboxylic acid
relationship: part_of GO:0015718 ! monocarboxylic acid transport

[Term]
id: GO:0008078
name: mesodermal cell migration
namespace: biological_process
def: "The orderly movement of mesodermal cells from one site to another." [GOC:ascb_2009, GOC:dph, GOC:mah, GOC:sat, GOC:tb, PMID:25119047]
synonym: "mesoderm cell migration" EXACT []
is_a: GO:0001667 ! ameboidal-type cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000222 ! mesodermal cell
relationship: results_in_movement_of CL:0000222 ! mesodermal cell

[Term]
id: GO:0008088
name: axo-dendritic transport
namespace: biological_process
def: "The directed movement of organelles or molecules along microtubules in neuron projections." [ISBN:0815316194]
subset: goslim_synapse
synonym: "axon cargo transport" NARROW []
synonym: "axonal transport" NARROW []
synonym: "axoplasmic transport" NARROW []
xref: Wikipedia:Axoplasmic_transport
is_a: GO:0010970 ! transport along microtubule
intersection_of: GO:0046907 ! intracellular transport
intersection_of: occurs_in GO:0043005 ! neuron projection
intersection_of: results_in_transport_along GO:0005874 ! microtubule
relationship: occurs_in GO:0043005 ! neuron projection

[Term]
id: GO:0008104
name: protein localization
namespace: biological_process
alt_id: GO:0008105
alt_id: GO:0016249
alt_id: GO:0034613
def: "Any process in which a protein is transported to, or maintained in, a specific location." [GOC:ai]
subset: goslim_drosophila
synonym: "asymmetric protein localisation" RELATED [GOC:mah]
synonym: "asymmetric protein localization" RELATED []
synonym: "cellular protein localisation" EXACT [GOC:mah]
synonym: "cellular protein localization" EXACT []
synonym: "channel localizer activity" NARROW [GOC:mah]
synonym: "establishment and maintenance of asymmetric protein localization" RELATED []
synonym: "establishment and maintenance of protein localization" RELATED []
synonym: "protein localisation" EXACT [GOC:mah]
is_a: GO:0070727 ! cellular macromolecule localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input PR:000000001 ! protein
relationship: has_primary_input PR:000000001 ! protein
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI

[Term]
id: GO:0008150
name: biological process
name: biological_process
namespace: biological_process
alt_id: GO:0000004
alt_id: GO:0007582
alt_id: GO:0044699
def: "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt]
def: "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt]
def: "A process that emerges from two or more causally-connected macromolecular activities and has evolved to achieve a biological objective." []
comment: A biological process is an evolved process
comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.
comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.
subset: goslim_candida
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_pombe
subset: goslim_yeast
synonym: "biological process" EXACT []
synonym: "physiological process" EXACT []
synonym: "single organism process" RELATED []
synonym: "single-organism process" RELATED []
xref: Wikipedia:Biological_process
is_a: BFO:0000015 ! process
relationship: has_part GO:0003674 ! molecular_function
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI
created_by: jl
creation_date: 2012-09-19T15:05:24Z

[Term]
id: GO:0008152
name: metabolic process
namespace: biological_process
alt_id: GO:0044236
alt_id: GO:0044710
def: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684]
comment: Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions.
subset: gocheck_do_not_manually_annotate
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
synonym: "metabolic process resulting in cell growth" NARROW []
synonym: "metabolism" EXACT []
synonym: "metabolism resulting in cell growth" NARROW []
synonym: "multicellular organism metabolic process" NARROW []
synonym: "single-organism metabolic process" RELATED []
xref: Wikipedia:Metabolism
is_a: GO:0008150 ! biological process
disjoint_from: GO:0051179 ! localization
created_by: jl
creation_date: 2012-10-17T15:46:40Z

[Term]
id: GO:0008202
name: steroid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [ISBN:0198547684]
synonym: "steroid metabolism" EXACT []
xref: Wikipedia:Steroid_metabolism
is_a: GO:0006629 ! lipid metabolic process
is_a: GO:1901360 ! organic cyclic compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:35341 ! steroid
relationship: has_primary_input_or_output CHEBI:35341 ! steroid

[Term]
id: GO:0008206
name: bile acid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:go_curators]
synonym: "bile acid metabolism" EXACT []
is_a: GO:0008202 ! steroid metabolic process
is_a: GO:0032787 ! monocarboxylic acid metabolic process
is_a: GO:1901615 ! organic hydroxy compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:36235 ! bile acid anion
relationship: has_primary_input_or_output CHEBI:36235 ! bile acid anion

[Term]
id: GO:0008219
name: cell death
namespace: biological_process
def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395]
comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms.
subset: gocheck_do_not_annotate
synonym: "accidental cell death" RELATED []
synonym: "necrosis" RELATED []
is_a: GO:0009987 ! cellular process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24680" xsd:anyURI

[Term]
id: GO:0008272
name: sulfate transport
namespace: biological_process
alt_id: GO:0006870
def: "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc]
synonym: "sulphate transport" EXACT []
is_a: GO:0015698 ! inorganic anion transport
is_a: GO:0072348 ! sulfur compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:16189 ! sulfate
relationship: has_primary_input CHEBI:16189 ! sulfate

[Term]
id: GO:0008283
name: cell population proliferation
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population." [GOC:mah, GOC:mb]
comment: This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms.
subset: goslim_agr
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_pir
synonym: "cell proliferation" RELATED []
is_a: GO:0009987 ! cellular process
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0008284
name: positive regulation of cell population proliferation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of cell proliferation." [GOC:go_curators]
synonym: "activation of cell proliferation" NARROW []
synonym: "positive regulation of cell proliferation" RELATED []
synonym: "stimulation of cell proliferation" NARROW []
synonym: "up regulation of cell proliferation" EXACT []
synonym: "up-regulation of cell proliferation" EXACT []
synonym: "upregulation of cell proliferation" EXACT []
is_a: GO:0042127 ! regulation of cell population proliferation
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008283 ! cell population proliferation
relationship: positively_regulates GO:0008283 ! cell population proliferation
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0008285
name: negative regulation of cell population proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators]
synonym: "down regulation of cell proliferation" EXACT []
synonym: "down-regulation of cell proliferation" EXACT []
synonym: "downregulation of cell proliferation" EXACT []
synonym: "inhibition of cell proliferation" NARROW []
synonym: "negative regulation of cell proliferation" RELATED []
is_a: GO:0042127 ! regulation of cell population proliferation
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008283 ! cell population proliferation
relationship: negatively_regulates GO:0008283 ! cell population proliferation
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0008291
name: acetylcholine metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:jl, GOC:nln, ISBN:0192800752]
synonym: "acetylcholine metabolism" EXACT []
is_a: GO:0006807 ! nitrogen compound metabolic process
is_a: GO:1900619 ! acetate ester metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:15355 ! acetylcholine
relationship: has_primary_input_or_output CHEBI:15355 ! acetylcholine

[Term]
id: GO:0008292
name: acetylcholine biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752]
synonym: "acetylcholine anabolism" EXACT []
synonym: "acetylcholine biosynthesis" EXACT []
synonym: "acetylcholine formation" EXACT []
synonym: "acetylcholine synthesis" EXACT []
is_a: GO:0008291 ! acetylcholine metabolic process
is_a: GO:1900620 ! acetate ester biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:15355 ! acetylcholine
relationship: has_primary_output CHEBI:15355 ! acetylcholine

[Term]
id: GO:0008320
name: protein transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0015266
alt_id: GO:0015463
def: "Enables the transfer of a protein from one side of a membrane to the other." [GOC:jl]
synonym: "protein channel activity" RELATED []
xref: Reactome:R-HSA-1268022 "TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space"
xref: Reactome:R-HSA-1299475 "TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix"
xref: Reactome:R-HSA-184269 "Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex"
xref: Reactome:R-HSA-3149434 "Transport of GAG to the Plasma Membrane"
xref: Reactome:R-HSA-5205661 "Pink1 is recruited from the cytoplasm to the mitochondria"
xref: Reactome:R-HSA-5210943 "pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol)"
xref: Reactome:R-HSA-5210947 "pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol)"
xref: Reactome:R-HSA-5228406 "tetX HC transports tetX LC from target cell endosome membrane into cytosol"
xref: Reactome:R-HSA-5229111 "AP4 transports APP from trans-Golgi network to endosome lumen"
xref: Reactome:R-HSA-5244404 "botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol"
xref: Reactome:R-HSA-5244428 "botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol"
xref: Reactome:R-HSA-5244506 "botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol"
xref: Reactome:R-HSA-5246514 "botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol"
xref: Reactome:R-HSA-5250616 "botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol"
xref: Reactome:R-HSA-5250884 "botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol"
xref: Reactome:R-HSA-5250972 "botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol"
xref: Reactome:R-HSA-5336420 "DT fragment B transports DT fragment A from target cell endosome membrane"
xref: Reactome:R-HSA-9636375 "SecA2 transports SapM from cytoplasm to cytosol"
xref: Reactome:R-HSA-9698930 "HCMV C Nucleocapsid Translocation"
xref: Reactome:R-HSA-9698933 "HCMV B Nucleocapsid Translocation"
is_a: GO:0022857 ! transmembrane transporter activity
is_a: GO:0140318 ! protein transporter activity
intersection_of: GO:0005215 ! transporter activity
intersection_of: has_primary_input PR:000000001 ! protein
intersection_of: results_in_transport_across GO:0016020 ! membrane
relationship: part_of GO:0071806 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! protein transmembrane transport

[Term]
id: GO:0008324
name: monoatomic cation transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of cation from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729]
synonym: "cation transmembrane transporter activity" BROAD []
synonym: "transmembrane cation transporter activity" EXACT []
is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation
relationship: has_primary_input CHEBI:23906 ! monoatomic cation
relationship: part_of GO:0098655 ! monoatomic cation transmembrane transport
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI

[Term]
id: GO:0008347
name: glial cell migration
namespace: biological_process
alt_id: GO:0043359
def: "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:jl, GOC:mtg_sensu]
synonym: "glia cell migration" EXACT []
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000125 ! glial cell
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of GO:0042063 ! gliogenesis
relationship: results_in_movement_of CL:0000125 ! glial cell

[Term]
id: GO:0008354
name: germ cell migration
namespace: biological_process
def: "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." [GOC:bf, GOC:jl]
synonym: "germ-cell migration" EXACT []
synonym: "primordial germ cell migration" RELATED []
is_a: GO:0016477 ! cell migration
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000586 ! germ cell
relationship: part_of GO:0007276 ! gamete generation
relationship: results_in_movement_of CL:0000586 ! germ cell

[Term]
id: GO:0008356
name: asymmetric cell division
namespace: biological_process
def: "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." [PMID:11672519]
synonym: "asymmetric cytokinesis" RELATED []
synonym: "asymmetrical cell division" EXACT []
synonym: "asymmetrical cytokinesis" RELATED []
xref: Wikipedia:Asymmetric_cell_division
is_a: GO:0051301 ! cell division

[Term]
id: GO:0008358
name: maternal determination of anterior/posterior axis, embryo
namespace: biological_process
def: "The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]
is_a: GO:0008595 ! anterior/posterior axis specification, embryo

[Term]
id: GO:0008406
name: gonad development
namespace: biological_process
def: "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." [GOC:ems, ISBN:0198506732]
synonym: "gonadogenesis" EXACT [GOC:cjm]
is_a: GO:0048513 ! animal organ development
is_a: GO:0048608 ! reproductive structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000991 ! gonad
relationship: part_of GO:0045137 ! development of primary sexual characteristics
relationship: results_in_development_of UBERON:0000991 ! gonad

[Term]
id: GO:0008504
name: monoamine transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0015201
def: "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." [GOC:mah]
xref: Reactome:R-HSA-372542 "Loading of dopamine into synaptic veiscles"
xref: Reactome:R-HSA-379393 "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol"
xref: Reactome:R-HSA-380586 "loading of Serotonin in synaptic vesicles"
xref: Reactome:R-HSA-380620 "Reuptake of serotonin from the synapse"
xref: Reactome:R-HSA-444160 "VMAT1/2 can mediate the transport of biogenic amines"
xref: Reactome:R-HSA-5660706 "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol"
is_a: GO:0022804 ! active transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:63534 ! monoamine
relationship: has_primary_input CHEBI:63534 ! monoamine
relationship: part_of GO:0015844 ! monoamine transport

[Term]
id: GO:0008514
name: organic anion transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai]
xref: Reactome:R-HSA-2142859 "Growing HA is extruded from the cell by ABCC5"
xref: Reactome:R-HSA-561041 "OAT1-3 transport organic anions with antiport of dicarboxylic acids"
xref: Reactome:R-HSA-9794830 "SLC22A8 transports Cipro into renal cell"
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:25696 ! organic anion
relationship: has_primary_input CHEBI:25696 ! organic anion
relationship: part_of GO:0015711 ! organic anion transport

[Term]
id: GO:0008544
name: epidermis development
namespace: biological_process
def: "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:go_curators, UBERON:0001003]
synonym: "hypodermis development" RELATED [GOC:kmv, GOC:rk]
is_a: GO:0009888 ! tissue development
property_value: RO:0002161 NCBITaxon:33090

[Term]
id: GO:0008584
name: male gonad development
namespace: biological_process
def: "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure." [GOC:jid]
synonym: "testicular development" EXACT [GOC:sl]
synonym: "testis development" EXACT [GOC:sl]
is_a: GO:0008406 ! gonad development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000473 ! testis
relationship: part_of GO:0046546 ! development of primary male sexual characteristics
relationship: results_in_development_of UBERON:0000473 ! testis

[Term]
id: GO:0008585
name: female gonad development
namespace: biological_process
alt_id: GO:0061039
def: "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:tb]
synonym: "ovarian development" RELATED [GOC:sl]
synonym: "ovary development" RELATED [GOC:sl]
is_a: GO:0008406 ! gonad development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000992 ! ovary
relationship: part_of GO:0046545 ! development of primary female sexual characteristics
relationship: results_in_development_of UBERON:0000992 ! ovary
property_value: RO:0002161 NCBITaxon:3398

[Term]
id: GO:0008594
name: photoreceptor cell morphogenesis
namespace: biological_process
def: "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster." [GOC:jid, GOC:mah]
synonym: "photoreceptor development" RELATED []
is_a: GO:0048667 ! cell morphogenesis involved in neuron differentiation
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of CL:0000210 ! photoreceptor cell
relationship: part_of GO:0042461 ! photoreceptor cell development
relationship: results_in_morphogenesis_of CL:0000210 ! photoreceptor cell

[Term]
id: GO:0008595
name: anterior/posterior axis specification, embryo
namespace: biological_process
def: "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]
synonym: "anterior/posterior axis determination, embryo" RELATED [GOC:dph]
is_a: GO:0000578 ! embryonic axis specification
is_a: GO:0009948 ! anterior/posterior axis specification
relationship: part_of GO:0007351 ! tripartite regional subdivision

[Term]
id: GO:0008610
name: lipid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators]
synonym: "lipid anabolism" EXACT []
synonym: "lipid biosynthesis" EXACT []
synonym: "lipid formation" EXACT []
synonym: "lipid synthesis" EXACT []
synonym: "lipogenesis" EXACT [GOC:sl]
is_a: GO:0006629 ! lipid metabolic process
is_a: GO:1901576 ! organic substance biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:18059 ! lipid
relationship: has_primary_output CHEBI:18059 ! lipid

[Term]
id: GO:0008643
name: carbohydrate transport
namespace: biological_process
alt_id: GO:0006861
alt_id: GO:0008644
def: "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y." [GOC:ai]
subset: goslim_pir
subset: goslim_yeast
synonym: "sugar transport" NARROW []
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:16646 ! carbohydrate
relationship: has_primary_input CHEBI:16646 ! carbohydrate

[Term]
id: GO:0008645
name: hexose transmembrane transport
namespace: biological_process
alt_id: GO:0008646
alt_id: GO:0008647
alt_id: GO:0035428
def: "The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule." [GOC:vw]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "hexose membrane transport" RELATED []
synonym: "hexose transport" RELATED []
synonym: "high-affinity hexose transport" NARROW []
synonym: "low-affinity hexose transport" NARROW []
is_a: GO:0015749 ! monosaccharide transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:18133 ! hexose
intersection_of: results_in_transport_across GO:0016020 ! membrane
relationship: has_primary_input CHEBI:18133 ! hexose
created_by: bf
creation_date: 2010-04-08T10:27:23Z

[Term]
id: GO:0008652
name: amino acid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." [ISBN:0198506732]
synonym: "amino acid anabolism" EXACT []
synonym: "amino acid biosynthesis" EXACT []
synonym: "amino acid formation" EXACT []
synonym: "amino acid synthesis" EXACT []
synonym: "cellular amino acid biosynthetic process" EXACT []
xref: Wikipedia:Amino_acid_synthesis
is_a: GO:0046394 ! carboxylic acid biosynthetic process
is_a: GO:1901566 ! organonitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:37022 ! amino-acid anion
relationship: has_primary_output CHEBI:37022 ! amino-acid anion
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI

[Term]
id: GO:0009056
name: catabolic process
namespace: biological_process
alt_id: GO:0044243
alt_id: GO:0044712
def: "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [ISBN:0198547684]
subset: goslim_agr
subset: goslim_chembl
subset: goslim_plant
synonym: "breakdown" EXACT []
synonym: "catabolism" EXACT []
synonym: "degradation" EXACT []
synonym: "multicellular organismal catabolic process" NARROW []
synonym: "single-organism catabolic process" RELATED []
xref: Wikipedia:Catabolism
is_a: GO:0008152 ! metabolic process
created_by: jl
creation_date: 2012-10-17T15:52:35Z

[Term]
id: GO:0009057
name: macromolecule catabolic process
namespace: biological_process
alt_id: GO:0043285
alt_id: GO:0044266
def: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah]
subset: goslim_pir
synonym: "biopolymer catabolic process" EXACT [GOC:mtg_chebi_dec09]
synonym: "cellular macromolecule catabolic process" RELATED []
synonym: "cellular macromolecule catabolism" RELATED []
synonym: "cellular macromolecule degradation" RELATED []
synonym: "macromolecule breakdown" EXACT []
synonym: "macromolecule catabolism" EXACT []
synonym: "macromolecule degradation" EXACT []
synonym: "multicellular organismal macromolecule catabolic process" NARROW []
is_a: GO:0043170 ! macromolecule metabolic process
is_a: GO:1901575 ! organic substance catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:33694 ! biomacromolecule
relationship: has_primary_input CHEBI:33694 ! biomacromolecule

[Term]
id: GO:0009058
name: biosynthetic process
namespace: biological_process
alt_id: GO:0044274
alt_id: GO:0044711
def: "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684]
subset: goslim_chembl
subset: goslim_metagenomics
subset: goslim_plant
synonym: "anabolism" EXACT []
synonym: "biosynthesis" EXACT []
synonym: "formation" BROAD []
synonym: "multicellular organismal biosynthetic process" NARROW []
synonym: "single-organism biosynthetic process" RELATED []
synonym: "synthesis" EXACT []
xref: Wikipedia:Anabolism
is_a: GO:0008152 ! metabolic process
created_by: jl
creation_date: 2012-10-17T15:52:18Z

[Term]
id: GO:0009059
name: macromolecule biosynthetic process
namespace: biological_process
alt_id: GO:0043284
def: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah]
subset: goslim_pir
synonym: "biopolymer biosynthetic process" EXACT [GOC:mtg_chebi_dec09]
synonym: "macromolecule anabolism" EXACT []
synonym: "macromolecule biosynthesis" EXACT []
synonym: "macromolecule formation" EXACT []
synonym: "macromolecule synthesis" EXACT []
is_a: GO:0043170 ! macromolecule metabolic process
is_a: GO:0044249 ! cellular biosynthetic process
is_a: GO:1901576 ! organic substance biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:33694 ! biomacromolecule
relationship: has_primary_output CHEBI:33694 ! biomacromolecule
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15249" xsd:anyURI
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25418" xsd:anyURI

[Term]
id: GO:0009063
name: amino acid catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." [GOC:ai]
synonym: "amino acid breakdown" EXACT []
synonym: "amino acid catabolism" EXACT []
synonym: "amino acid degradation" EXACT []
synonym: "cellular amino acid catabolic process" EXACT []
is_a: GO:0046395 ! carboxylic acid catabolic process
is_a: GO:1901565 ! organonitrogen compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:37022 ! amino-acid anion
relationship: has_primary_input CHEBI:37022 ! amino-acid anion
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI

[Term]
id: GO:0009100
name: glycoprotein metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732]
subset: goslim_drosophila
synonym: "glycoprotein metabolism" EXACT []
is_a: GO:0043170 ! macromolecule metabolic process
is_a: GO:1901135 ! carbohydrate derivative metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:17089 ! glycoprotein
relationship: has_primary_input_or_output CHEBI:17089 ! glycoprotein

[Term]
id: GO:0009101
name: glycoprotein biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732]
synonym: "glycoprotein anabolism" EXACT []
synonym: "glycoprotein biosynthesis" EXACT []
synonym: "glycoprotein formation" EXACT []
synonym: "glycoprotein synthesis" EXACT []
is_a: GO:0009059 ! macromolecule biosynthetic process
is_a: GO:0009100 ! glycoprotein metabolic process
is_a: GO:1901137 ! carbohydrate derivative biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:17089 ! glycoprotein
relationship: has_primary_output CHEBI:17089 ! glycoprotein

[Term]
id: GO:0009112
name: nucleobase metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." [GOC:ma]
synonym: "nucleobase metabolism" EXACT []
is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process
is_a: GO:1901564 ! organonitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:18282 ! nucleobase
relationship: has_primary_input_or_output CHEBI:18282 ! nucleobase

[Term]
id: GO:0009250
name: glucan biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators]
synonym: "glucan anabolism" EXACT []
synonym: "glucan biosynthesis" EXACT []
synonym: "glucan formation" EXACT []
synonym: "glucan synthesis" EXACT []
is_a: GO:0000271 ! polysaccharide biosynthetic process
is_a: GO:0044042 ! glucan metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:37163 ! glucan
relationship: has_primary_output CHEBI:37163 ! glucan

[Term]
id: GO:0009251
name: glucan catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators]
synonym: "glucan breakdown" EXACT []
synonym: "glucan catabolism" EXACT []
synonym: "glucan degradation" EXACT []
is_a: GO:0000272 ! polysaccharide catabolic process
is_a: GO:0044042 ! glucan metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:37163 ! glucan
relationship: has_primary_input CHEBI:37163 ! glucan

[Term]
id: GO:0009306
name: protein secretion
namespace: biological_process
alt_id: GO:0045166
alt_id: GO:0045731
def: "The controlled release of proteins from a cell." [GOC:ai]
synonym: "glycoprotein secretion" NARROW []
synonym: "protein secretion during cell fate commitment" NARROW []
synonym: "protein secretion resulting in cell fate commitment" NARROW []
is_a: GO:0015031 ! protein transport
is_a: GO:0032940 ! secretion by cell
is_a: GO:0035592 ! establishment of protein localization to extracellular region
is_a: GO:0071692 ! protein localization to extracellular region
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input PR:000000001 ! protein

[Term]
id: GO:0009308
name: amine metabolic process
namespace: biological_process
alt_id: GO:0044106
def: "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732]
subset: goslim_chembl
subset: goslim_pir
synonym: "amine metabolism" EXACT []
synonym: "cellular amine metabolic process" EXACT []
is_a: GO:1901564 ! organonitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:32952 ! amine
relationship: has_primary_input_or_output CHEBI:32952 ! amine
created_by: jl
creation_date: 2009-07-15T11:55:44Z

[Term]
id: GO:0009309
name: amine biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732]
synonym: "amine anabolism" EXACT []
synonym: "amine biosynthesis" EXACT []
synonym: "amine formation" EXACT []
synonym: "amine synthesis" EXACT []
is_a: GO:0009308 ! amine metabolic process
is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process
is_a: GO:1901566 ! organonitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:32952 ! amine
relationship: has_primary_output CHEBI:32952 ! amine

[Term]
id: GO:0009310
name: amine catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732]
synonym: "amine breakdown" EXACT []
synonym: "amine catabolism" EXACT []
synonym: "amine degradation" EXACT []
is_a: GO:0009308 ! amine metabolic process
is_a: GO:1901565 ! organonitrogen compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:32952 ! amine
relationship: has_primary_input CHEBI:32952 ! amine

[Term]
id: GO:0009314
name: response to radiation
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." [GOC:jl, Wikipedia:Electromagnetic_radiation]
comment: Note that 'radiation' refers to electromagnetic radiation of any wavelength.
synonym: "response to electromagnetic radiation stimulus" EXACT []
synonym: "response to radiation stimulus" EXACT []
is_a: GO:0009628 ! response to abiotic stimulus

[Term]
id: GO:0009416
name: response to light stimulus
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." [GOC:go_curators, ISBN:0582227089]
subset: goslim_plant
is_a: GO:0009314 ! response to radiation
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:30212 ! photon
relationship: has_primary_input CHEBI:30212 ! photon

[Term]
id: GO:0009566
name: fertilization
namespace: biological_process
def: "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:tb, ISBN:0198506732]
synonym: "syngamy" EXACT []
xref: Wikipedia:Fertilisation
is_a: GO:0022414 ! reproductive process
intersection_of: GO:0022414 ! reproductive process
intersection_of: results_in_formation_of_anatomical_entity CL:0010017 ! zygote
intersection_of: results_in_fusion_of GO:0043073 ! germ cell nucleus
relationship: part_of GO:0019953 ! sexual reproduction
relationship: results_in_formation_of_anatomical_entity CL:0010017 ! zygote
relationship: results_in_fusion_of GO:0043073 ! germ cell nucleus
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20176" xsd:anyURI

[Term]
id: GO:0009581
name: detection of external stimulus
namespace: biological_process
def: "The series of events in which an external stimulus is received by a cell and converted into a molecular signal." [GOC:hb]
synonym: "perception of external stimulus" RELATED []
is_a: GO:0009605 ! response to external stimulus
is_a: GO:0051606 ! detection of stimulus

[Term]
id: GO:0009582
name: detection of abiotic stimulus
namespace: biological_process
def: "The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal." [GOC:hb]
synonym: "perception of abiotic stimulus" RELATED []
is_a: GO:0009628 ! response to abiotic stimulus
is_a: GO:0051606 ! detection of stimulus

[Term]
id: GO:0009583
name: detection of light stimulus
namespace: biological_process
def: "The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal." [GOC:go_curators]
synonym: "detection of light" EXACT []
synonym: "perception of light" RELATED []
is_a: GO:0009416 ! response to light stimulus
is_a: GO:0009581 ! detection of external stimulus
is_a: GO:0009582 ! detection of abiotic stimulus

[Term]
id: GO:0009584
name: detection of visible light
namespace: biological_process
def: "The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm." [GOC:go_curators, ISBN:0198506732]
synonym: "perception of visible light" RELATED []
is_a: GO:0009583 ! detection of light stimulus

[Term]
id: GO:0009593
name: detection of chemical stimulus
namespace: biological_process
def: "The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal." [GOC:jl]
synonym: "chemoperception" EXACT []
synonym: "chemoreception" RELATED []
synonym: "detection of chemical substance" EXACT []
synonym: "perception of chemical stimulus" RELATED []
synonym: "perception of chemical substance" RELATED []
is_a: GO:0051606 ! detection of stimulus
relationship: part_of GO:0042221 ! response to chemical

[Term]
id: GO:0009605
name: response to external stimulus
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." [GOC:hb]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
subset: goslim_drosophila
subset: goslim_plant
synonym: "response to environmental stimulus" EXACT []
is_a: GO:0050896 ! response to stimulus

[Term]
id: GO:0009607
name: response to biotic stimulus
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." [GOC:hb]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
subset: goslim_metagenomics
subset: goslim_plant
synonym: "response to biotic stress" NARROW []
is_a: GO:0050896 ! response to stimulus

[Term]
id: GO:0009617
name: response to bacterium
namespace: biological_process
alt_id: GO:0009618
alt_id: GO:0009680
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium." [GOC:hb]
synonym: "response to bacteria" EXACT []
is_a: GO:0051707 ! response to other organism
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input NCBITaxon:2 ! Bacteria
relationship: has_primary_input NCBITaxon:2 ! Bacteria

[Term]
id: GO:0009620
name: response to fungus
namespace: biological_process
alt_id: GO:0009621
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus." [GOC:hb]
synonym: "response to fungi" EXACT []
is_a: GO:0051707 ! response to other organism
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input NCBITaxon:4751 ! Fungi
relationship: has_primary_input NCBITaxon:4751 ! Fungi

[Term]
id: GO:0009628
name: response to abiotic stimulus
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." [GOC:hb]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
subset: goslim_metagenomics
subset: goslim_plant
synonym: "response to abiotic stress" NARROW []
is_a: GO:0050896 ! response to stimulus
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16572" xsd:anyURI

[Term]
id: GO:0009636
name: response to toxic substance
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:lr]
subset: goslim_chembl
synonym: "detoxification response" NARROW []
synonym: "toxin resistance" RELATED []
synonym: "toxin susceptibility/resistance" RELATED []
is_a: GO:0042221 ! response to chemical

[Term]
id: GO:0009653
name: anatomical structure morphogenesis
namespace: biological_process
def: "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." [GOC:go_curators, ISBN:0521436125]
synonym: "anatomical structure organization" EXACT []
synonym: "embryogenesis and morphogenesis" BROAD []
synonym: "morphogenesis" EXACT []
xref: Wikipedia:Morphogenesis
is_a: GO:0032502 ! developmental process
disjoint_from: GO:0048856 ! anatomical structure development
disjoint_from: GO:0071695 ! anatomical structure maturation
relationship: part_of GO:0048856 ! anatomical structure development

[Term]
id: GO:0009712
name: catechol-containing compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent." [GOC:sm, ISBN:0198547684]
synonym: "catechol metabolic process" RELATED []
synonym: "catechol metabolism" RELATED []
is_a: GO:0018958 ! phenol-containing compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:33566 ! catechols
relationship: has_primary_input_or_output CHEBI:33566 ! catechols

[Term]
id: GO:0009713
name: catechol-containing compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators]
synonym: "catechol anabolism" RELATED []
synonym: "catechol biosynthesis" RELATED []
synonym: "catechol biosynthetic process" RELATED []
synonym: "catechol formation" RELATED []
synonym: "catechol synthesis" RELATED []
is_a: GO:0009712 ! catechol-containing compound metabolic process
is_a: GO:0046189 ! phenol-containing compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:33566 ! catechols
relationship: has_primary_output CHEBI:33566 ! catechols

[Term]
id: GO:0009719
name: response to endogenous stimulus
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." [GOC:sm]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
subset: goslim_plant
is_a: GO:0050896 ! response to stimulus

[Term]
id: GO:0009725
name: response to hormone
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." [GOC:jl]
synonym: "growth regulator" RELATED []
synonym: "response to hormone stimulus" EXACT [GOC:dos]
is_a: GO:0009719 ! response to endogenous stimulus
is_a: GO:0010033 ! response to organic substance

[Term]
id: GO:0009743
name: response to carbohydrate
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." [GOC:jl]
synonym: "response to carbohydrate stimulus" EXACT [GOC:dos]
is_a: GO:0010033 ! response to organic substance
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:16646 ! carbohydrate
relationship: has_primary_input CHEBI:16646 ! carbohydrate

[Term]
id: GO:0009746
name: response to hexose
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." [GOC:jl]
synonym: "response to hexose stimulus" EXACT [GOC:dos]
is_a: GO:0034284 ! response to monosaccharide
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:18133 ! hexose
relationship: has_primary_input CHEBI:18133 ! hexose

[Term]
id: GO:0009749
name: response to glucose
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." [GOC:jl]
synonym: "response to glucose stimulus" EXACT [GOC:dos]
is_a: GO:0009746 ! response to hexose
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:17234 ! glucose
relationship: has_primary_input CHEBI:17234 ! glucose

[Term]
id: GO:0009786
name: regulation of asymmetric cell division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of asymmetric cell division." [GOC:lr]
is_a: GO:0051302 ! regulation of cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008356 ! asymmetric cell division
relationship: regulates GO:0008356 ! asymmetric cell division

[Term]
id: GO:0009790
name: embryo development
namespace: biological_process
alt_id: GO:0009795
def: "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu]
subset: gocheck_do_not_manually_annotate
subset: goslim_chembl
subset: goslim_plant
synonym: "embryogenesis" EXACT []
synonym: "embryogenesis and morphogenesis" BROAD []
synonym: "embryonal development" EXACT []
xref: Wikipedia:Embryogenesis
is_a: GO:0007275 ! multicellular organism development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000922 ! embryo
relationship: results_in_development_of UBERON:0000922 ! embryo

[Term]
id: GO:0009791
name: post-embryonic development
namespace: biological_process
def: "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." [GOC:go_curators]
subset: goslim_plant
is_a: GO:0032501 ! multicellular organismal process
relationship: part_of GO:0007275 ! multicellular organism development

[Term]
id: GO:0009792
name: embryo development ending in birth or egg hatching
namespace: biological_process
def: "The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu]
synonym: "embryogenesis" BROAD []
is_a: GO:0009790 ! embryo development
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa

[Term]
id: GO:0009798
name: axis specification
namespace: biological_process
def: "The establishment, maintenance and elaboration of a pattern along a line or around a point." [GOC:dph, GOC:go_curators, GOC:isa_complete]
synonym: "axis determination" RELATED []
is_a: GO:0007389 ! pattern specification process

[Term]
id: GO:0009820
name: alkaloid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743]
subset: goslim_chembl
synonym: "alkaloid metabolism" EXACT []
is_a: GO:1901564 ! organonitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:22315 ! alkaloid
relationship: has_primary_input_or_output CHEBI:22315 ! alkaloid

[Term]
id: GO:0009821
name: alkaloid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743]
synonym: "alkaloid anabolism" EXACT []
synonym: "alkaloid biosynthesis" EXACT []
synonym: "alkaloid formation" EXACT []
synonym: "alkaloid synthesis" EXACT []
xref: UM-BBD_enzymeID:e0711
is_a: GO:0009820 ! alkaloid metabolic process
is_a: GO:0044550 ! secondary metabolite biosynthetic process
is_a: GO:1901566 ! organonitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:22315 ! alkaloid
relationship: has_primary_output CHEBI:22315 ! alkaloid

[Term]
id: GO:0009822
name: alkaloid catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743]
synonym: "alkaloid breakdown" EXACT []
synonym: "alkaloid catabolism" EXACT []
synonym: "alkaloid degradation" EXACT []
is_a: GO:0009820 ! alkaloid metabolic process
is_a: GO:0044270 ! cellular nitrogen compound catabolic process
is_a: GO:1901565 ! organonitrogen compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:22315 ! alkaloid
relationship: has_primary_input CHEBI:22315 ! alkaloid

[Term]
id: GO:0009880
name: embryonic pattern specification
namespace: biological_process
def: "The process that results in the patterns of cell differentiation that will arise in an embryo." [GOC:go_curators, ISBN:0521436125]
synonym: "embryonic pattern biosynthesis" BROAD []
synonym: "embryonic pattern formation" BROAD []
synonym: "ventral/lateral system" RELATED []
is_a: GO:0007389 ! pattern specification process
relationship: part_of GO:0009790 ! embryo development

[Term]
id: GO:0009887
name: animal organ morphogenesis
namespace: biological_process
def: "Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dgh, GOC:go_curators, ISBN:0471245208, ISBN:0721662544]
synonym: "histogenesis and organogenesis" BROAD []
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000062 ! organ
relationship: part_of GO:0048513 ! animal organ development
relationship: results_in_morphogenesis_of UBERON:0000062 ! organ

[Term]
id: GO:0009888
name: tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." [ISBN:0471245208]
synonym: "histogenesis" EXACT []
synonym: "histogenesis and organogenesis" BROAD []
xref: Wikipedia:Histogenesis
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000479 ! tissue
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
relationship: results_in_development_of UBERON:0000479 ! tissue
property_value: RO:0002161 NCBITaxon:147554
property_value: RO:0002161 NCBITaxon:33630
property_value: RO:0002161 NCBITaxon:33682
property_value: RO:0002161 NCBITaxon:38254
property_value: RO:0002161 NCBITaxon:4891

[Term]
id: GO:0009889
name: regulation of biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators]
synonym: "regulation of anabolism" EXACT []
synonym: "regulation of biosynthesis" EXACT []
synonym: "regulation of formation" EXACT []
synonym: "regulation of synthesis" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009058 ! biosynthetic process
relationship: regulates GO:0009058 ! biosynthetic process

[Term]
id: GO:0009890
name: negative regulation of biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators]
synonym: "down regulation of biosynthetic process" EXACT []
synonym: "down-regulation of biosynthetic process" EXACT []
synonym: "downregulation of biosynthetic process" EXACT []
synonym: "inhibition of biosynthetic process" NARROW []
synonym: "negative regulation of anabolism" EXACT []
synonym: "negative regulation of biosynthesis" EXACT []
synonym: "negative regulation of formation" EXACT []
synonym: "negative regulation of synthesis" EXACT []
is_a: GO:0009889 ! regulation of biosynthetic process
is_a: GO:0009892 ! negative regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009058 ! biosynthetic process
relationship: negatively_regulates GO:0009058 ! biosynthetic process

[Term]
id: GO:0009891
name: positive regulation of biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators]
synonym: "activation of biosynthetic process" NARROW []
synonym: "positive regulation of anabolism" EXACT []
synonym: "positive regulation of biosynthesis" EXACT []
synonym: "positive regulation of formation" EXACT []
synonym: "positive regulation of synthesis" EXACT []
synonym: "stimulation of biosynthetic process" NARROW []
synonym: "up regulation of biosynthetic process" EXACT []
synonym: "up-regulation of biosynthetic process" EXACT []
synonym: "upregulation of biosynthetic process" EXACT []
is_a: GO:0009889 ! regulation of biosynthetic process
is_a: GO:0009893 ! positive regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009058 ! biosynthetic process
relationship: positively_regulates GO:0009058 ! biosynthetic process

[Term]
id: GO:0009892
name: negative regulation of metabolic process
namespace: biological_process
alt_id: GO:0044252
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators]
synonym: "down regulation of metabolic process" EXACT []
synonym: "down-regulation of metabolic process" EXACT []
synonym: "downregulation of metabolic process" EXACT []
synonym: "inhibition of metabolic process" NARROW []
synonym: "inhibition of organismal metabolic process" NARROW []
synonym: "negative regulation of metabolism" EXACT []
synonym: "negative regulation of multicellular organismal metabolic process" NARROW []
synonym: "negative regulation of organismal metabolism" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008152 ! metabolic process
relationship: negatively_regulates GO:0008152 ! metabolic process

[Term]
id: GO:0009893
name: positive regulation of metabolic process
namespace: biological_process
alt_id: GO:0044253
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators]
synonym: "activation of metabolic process" NARROW []
synonym: "positive regulation of metabolism" EXACT []
synonym: "positive regulation of multicellular organismal metabolic process" NARROW []
synonym: "positive regulation of organismal metabolism" NARROW []
synonym: "stimulation of metabolic process" NARROW []
synonym: "stimulation of organismal metabolic process" NARROW []
synonym: "up regulation of metabolic process" EXACT []
synonym: "up-regulation of metabolic process" EXACT []
synonym: "up-regulation of organismal metabolic process" NARROW []
synonym: "upregulation of metabolic process" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008152 ! metabolic process
relationship: positively_regulates GO:0008152 ! metabolic process

[Term]
id: GO:0009894
name: regulation of catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators]
synonym: "regulation of breakdown" EXACT []
synonym: "regulation of catabolism" EXACT []
synonym: "regulation of degradation" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009056 ! catabolic process
relationship: regulates GO:0009056 ! catabolic process

[Term]
id: GO:0009895
name: negative regulation of catabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators]
synonym: "down regulation of catabolic process" EXACT []
synonym: "down-regulation of catabolic process" EXACT []
synonym: "downregulation of catabolic process" EXACT []
synonym: "inhibition of catabolic process" NARROW []
synonym: "negative regulation of breakdown" EXACT []
synonym: "negative regulation of catabolism" EXACT []
synonym: "negative regulation of degradation" EXACT []
is_a: GO:0009892 ! negative regulation of metabolic process
is_a: GO:0009894 ! regulation of catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009056 ! catabolic process
relationship: negatively_regulates GO:0009056 ! catabolic process

[Term]
id: GO:0009896
name: positive regulation of catabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators]
synonym: "activation of catabolic process" NARROW []
synonym: "positive regulation of breakdown" EXACT []
synonym: "positive regulation of catabolism" EXACT []
synonym: "positive regulation of degradation" EXACT []
synonym: "stimulation of catabolic process" NARROW []
synonym: "up regulation of catabolic process" EXACT []
synonym: "up-regulation of catabolic process" EXACT []
synonym: "upregulation of catabolic process" EXACT []
is_a: GO:0009893 ! positive regulation of metabolic process
is_a: GO:0009894 ! regulation of catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009056 ! catabolic process
relationship: positively_regulates GO:0009056 ! catabolic process

[Term]
id: GO:0009913
name: epidermal cell differentiation
namespace: biological_process
alt_id: GO:0043355
def: "The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis." [GOC:dph, GOC:go_curators, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb]
synonym: "hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk]
is_a: GO:0030855 ! epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000362 ! epidermal cell
relationship: part_of GO:0008544 ! epidermis development
relationship: results_in_acquisition_of_features_of CL:0000362 ! epidermal cell

[Term]
id: GO:0009914
name: hormone transport
namespace: biological_process
def: "The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:tb]
subset: goslim_pir
is_a: GO:0006810 ! transport
is_a: GO:0010817 ! regulation of hormone levels

[Term]
id: GO:0009948
name: anterior/posterior axis specification
namespace: biological_process
def: "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "anterior/posterior axis determination" RELATED [GOC:dph]
is_a: GO:0009798 ! axis specification
relationship: part_of GO:0009952 ! anterior/posterior pattern specification

[Term]
id: GO:0009952
name: anterior/posterior pattern specification
namespace: biological_process
def: "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb]
synonym: "anterior/posterior pattern formation" RELATED []
is_a: GO:0003002 ! regionalization

[Term]
id: GO:0009966
name: regulation of signal transduction
namespace: biological_process
alt_id: GO:0035466
def: "Any process that modulates the frequency, rate or extent of signal transduction." [GOC:sm]
synonym: "regulation of signaling pathway" RELATED []
synonym: "regulation of signalling pathway" RELATED [GOC:mah]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0023051 ! regulation of signaling
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007165 ! signal transduction
relationship: regulates GO:0007165 ! signal transduction

[Term]
id: GO:0009967
name: positive regulation of signal transduction
namespace: biological_process
alt_id: GO:0035468
def: "Any process that activates or increases the frequency, rate or extent of signal transduction." [GOC:sm]
synonym: "activation of signal transduction" NARROW []
synonym: "positive regulation of signaling pathway" RELATED []
synonym: "positive regulation of signalling pathway" RELATED [GOC:mah]
synonym: "stimulation of signal transduction" NARROW []
synonym: "up regulation of signal transduction" EXACT []
synonym: "up-regulation of signal transduction" EXACT []
synonym: "upregulation of signal transduction" EXACT []
is_a: GO:0009966 ! regulation of signal transduction
is_a: GO:0010647 ! positive regulation of cell communication
is_a: GO:0023056 ! positive regulation of signaling
is_a: GO:0048584 ! positive regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007165 ! signal transduction
relationship: positively_regulates GO:0007165 ! signal transduction

[Term]
id: GO:0009968
name: negative regulation of signal transduction
namespace: biological_process
alt_id: GO:0035467
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." [GOC:sm]
synonym: "down regulation of signal transduction" EXACT []
synonym: "down-regulation of signal transduction" EXACT []
synonym: "downregulation of signal transduction" EXACT []
synonym: "inhibition of signal transduction" NARROW []
synonym: "negative regulation of signaling pathway" RELATED []
synonym: "negative regulation of signalling pathway" RELATED [GOC:mah]
is_a: GO:0009966 ! regulation of signal transduction
is_a: GO:0010648 ! negative regulation of cell communication
is_a: GO:0023057 ! negative regulation of signaling
is_a: GO:0048585 ! negative regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007165 ! signal transduction
relationship: negatively_regulates GO:0007165 ! signal transduction

[Term]
id: GO:0009987
name: cellular process
namespace: biological_process
alt_id: GO:0008151
alt_id: GO:0044763
alt_id: GO:0050875
def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete]
comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term.
subset: gocheck_do_not_annotate
subset: goslim_plant
synonym: "cell growth and/or maintenance" NARROW []
synonym: "cell physiology" EXACT []
synonym: "cellular physiological process" EXACT []
synonym: "single-organism cellular process" RELATED []
is_a: GO:0008150 ! biological process
created_by: jl
creation_date: 2012-12-11T16:56:55Z

[Term]
id: GO:0009994
name: oocyte differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete." [GOC:go_curators, GOC:mtg_sensu]
synonym: "oocyte cell differentiation" EXACT []
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000023 ! oocyte
relationship: part_of GO:0048477 ! oogenesis
relationship: results_in_acquisition_of_features_of CL:0000023 ! oocyte

[Term]
id: GO:0010001
name: glial cell differentiation
namespace: biological_process
alt_id: GO:0007404
alt_id: GO:0043360
def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell." [GOC:go_curators, GOC:mtg_sensu]
synonym: "glia cell differentiation" EXACT []
synonym: "neuroglia differentiation" EXACT []
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000125 ! glial cell
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of GO:0042063 ! gliogenesis
relationship: results_in_acquisition_of_features_of CL:0000125 ! glial cell

[Term]
id: GO:0010002
name: cardioblast differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators]
synonym: "cardiac precursor cell differentiation" EXACT [GOC:mtg_heart]
synonym: "cardioblast cell differentiation" EXACT []
synonym: "cardiomyocyte generation" RELATED []
is_a: GO:0035051 ! cardiocyte differentiation
is_a: GO:0048863 ! stem cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002664 ! cardioblast
relationship: results_in_acquisition_of_features_of CL:0002664 ! cardioblast

[Term]
id: GO:0010032
name: meiotic chromosome condensation
namespace: biological_process
def: "Compaction of chromatin structure prior to meiosis in eukaryotic cells." [PMID:10072401]
synonym: "chromosome condensation involved in meiotic cell cycle" EXACT [GOC:dph, GOC:tb]
is_a: GO:0030261 ! chromosome condensation
is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle
intersection_of: GO:0030261 ! chromosome condensation
intersection_of: part_of GO:0051321 ! meiotic cell cycle

[Term]
id: GO:0010033
name: response to organic substance
namespace: biological_process
alt_id: GO:1990367
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." [GOC:sm, PMID:23356676]
synonym: "process resulting in tolerance to organic substance" NARROW []
is_a: GO:0042221 ! response to chemical
intersection_of: GO:0042221 ! response to chemical
intersection_of: has_primary_input CHEBI:50860 ! organic molecular entity
relationship: has_primary_input CHEBI:50860 ! organic molecular entity

[Term]
id: GO:0010034
name: response to acetate
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." [GOC:sm]
is_a: GO:0010033 ! response to organic substance
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:30089 ! acetate
relationship: has_primary_input CHEBI:30089 ! acetate

[Term]
id: GO:0010035
name: response to inorganic substance
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." [GOC:sm]
is_a: GO:0042221 ! response to chemical
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:24835 ! inorganic molecular entity
relationship: has_primary_input CHEBI:24835 ! inorganic molecular entity

[Term]
id: GO:0010038
name: response to metal ion
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." [GOC:sm]
synonym: "heavy metal sensitivity/resistance" RELATED []
synonym: "response to heavy metal" NARROW []
synonym: "response to metal" EXACT []
is_a: GO:0010035 ! response to inorganic substance
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:25213 ! metal cation
relationship: has_primary_input CHEBI:25213 ! metal cation

[Term]
id: GO:0010070
name: zygote asymmetric cell division
namespace: biological_process
def: "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials." [GOC:tb]
synonym: "zygote asymmetric cytokinesis" RELATED []
is_a: GO:0008356 ! asymmetric cell division
intersection_of: GO:0008356 ! asymmetric cell division
intersection_of: has_primary_input CL:0000365 ! animal zygote
relationship: has_primary_input CL:0000365 ! animal zygote

[Term]
id: GO:0010160
name: formation of animal organ boundary
namespace: biological_process
alt_id: GO:0048862
def: "The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues." [GOC:dph, GOC:isa_complete, PMID:9611175]
synonym: "organ boundary specification" EXACT []
is_a: GO:0003002 ! regionalization
is_a: GO:0048859 ! formation of anatomical boundary
intersection_of: GO:0048859 ! formation of anatomical boundary
intersection_of: occurs_in UBERON:0000062 ! organ
relationship: occurs_in UBERON:0000062 ! organ
relationship: part_of GO:0048645 ! animal organ formation

[Term]
id: GO:0010171
name: body morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the soma are generated and organized." [GOC:ems, ISBN:0140512888]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000468 ! multicellular organism
relationship: results_in_morphogenesis_of UBERON:0000468 ! multicellular organism

[Term]
id: GO:0010200
name: response to chitin
namespace: biological_process
def: "A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus." [GOC:sm]
is_a: GO:0010243 ! response to organonitrogen compound
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:17029 ! chitin
relationship: has_primary_input CHEBI:17029 ! chitin

[Term]
id: GO:0010243
name: response to organonitrogen compound
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." [PMID:9869419]
synonym: "response to organic nitrogen" EXACT []
is_a: GO:0010033 ! response to organic substance
is_a: GO:1901698 ! response to nitrogen compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:35352 ! organonitrogen compound
relationship: has_primary_input CHEBI:35352 ! organonitrogen compound

[Term]
id: GO:0010256
name: endomembrane system organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system." [GOC:mah, GOC:sm]
subset: goslim_drosophila
synonym: "endomembrane organization" EXACT []
synonym: "endomembrane system organisation" EXACT [GOC:mah]
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0012505 ! endomembrane system
relationship: results_in_organization_of GO:0012505 ! endomembrane system

[Term]
id: GO:0010324
name: membrane invagination
namespace: biological_process
alt_id: GO:1902534
def: "The infolding of a membrane." [GOC:tb]
subset: goslim_yeast
synonym: "single-organism membrane invagination" RELATED []
is_a: GO:0061024 ! membrane organization
created_by: jl
creation_date: 2013-12-02T13:58:34Z

[Term]
id: GO:0010453
name: regulation of cell fate commitment
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb]
is_a: GO:0050793 ! regulation of developmental process
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0045165 ! cell fate commitment
relationship: regulates GO:0045165 ! cell fate commitment

[Term]
id: GO:0010454
name: negative regulation of cell fate commitment
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb]
is_a: GO:0010453 ! regulation of cell fate commitment
is_a: GO:0045596 ! negative regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045165 ! cell fate commitment
relationship: negatively_regulates GO:0045165 ! cell fate commitment

[Term]
id: GO:0010455
name: positive regulation of cell fate commitment
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb]
is_a: GO:0010453 ! regulation of cell fate commitment
is_a: GO:0045597 ! positive regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0045165 ! cell fate commitment
relationship: positively_regulates GO:0045165 ! cell fate commitment

[Term]
id: GO:0010463
name: mesenchymal cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0008019 ! mesenchymal cell
relationship: acts_on_population_of CL:0008019 ! mesenchymal cell

[Term]
id: GO:0010464
name: regulation of mesenchymal cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010463 ! mesenchymal cell proliferation
relationship: regulates GO:0010463 ! mesenchymal cell proliferation

[Term]
id: GO:0010467
name: gene expression
namespace: biological_process
def: "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes." [GOC:txnOH-2018, PMID:25934543, PMID:31580950]
subset: goslim_flybase_ribbon
xref: Wikipedia:Gene_expression
is_a: GO:0009059 ! macromolecule biosynthetic process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25419" xsd:anyURI

[Term]
id: GO:0010468
name: regulation of gene expression
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018]
comment: This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation.
synonym: "gene regulation" RELATED [GOC:cjm]
synonym: "regulation of gene product expression" RELATED []
synonym: "regulation of protein expression" NARROW []
xref: Wikipedia:Regulation_of_gene_expression
is_a: GO:0010556 ! regulation of macromolecule biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010467 ! gene expression
relationship: regulates GO:0010467 ! gene expression
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI

[Term]
id: GO:0010470
name: regulation of gastrulation
namespace: biological_process
def: "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." [GOC:dph, GOC:tb]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
is_a: GO:0045995 ! regulation of embryonic development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007369 ! gastrulation
relationship: regulates GO:0007369 ! gastrulation

[Term]
id: GO:0010481
name: epidermal cell division
namespace: biological_process
def: "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells." [PMID:17450124]
synonym: "hypodermal cell division" RELATED [GOC:kmv, GOC:rk]
is_a: GO:0051301 ! cell division
intersection_of: GO:0051301 ! cell division
intersection_of: has_primary_input CL:0000362 ! epidermal cell
relationship: has_primary_input CL:0000362 ! epidermal cell

[Term]
id: GO:0010482
name: regulation of epidermal cell division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis." [PMID:17450124]
synonym: "regulation of hypodermal cell division" RELATED [GOC:kmv, GOC:rk]
is_a: GO:0051302 ! regulation of cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010481 ! epidermal cell division
relationship: regulates GO:0010481 ! epidermal cell division

[Term]
id: GO:0010496
name: intercellular transport
namespace: biological_process
alt_id: GO:1902585
def: "The movement of substances between cells." [GOC:dhl]
synonym: "single organism intercellular transport" RELATED [GOC:TermGenie]
synonym: "single-organism intercellular transport" RELATED []
is_a: GO:0006810 ! transport
is_a: GO:0009987 ! cellular process
intersection_of: GO:0006810 ! transport
intersection_of: has_target_end_location CL:0000000 ! cell
intersection_of: has_target_start_location CL:0000000 ! cell
intersection_of: results_in_transport_across GO:0005615 ! extracellular space
relationship: has_target_end_location CL:0000000 ! cell
relationship: has_target_start_location CL:0000000 ! cell
relationship: results_in_transport_across GO:0005615 ! extracellular space
created_by: jl
creation_date: 2013-12-19T13:24:56Z

[Term]
id: GO:0010549
name: regulation of membrane disassembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of membrane disassembly." [GOC:dph, GOC:tb]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030397 ! membrane disassembly
relationship: regulates GO:0030397 ! membrane disassembly

[Term]
id: GO:0010556
name: regulation of macromolecule biosynthetic process
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb]
is_a: GO:0031326 ! regulation of cellular biosynthetic process
is_a: GO:0060255 ! regulation of macromolecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009059 ! macromolecule biosynthetic process
relationship: regulates GO:0009059 ! macromolecule biosynthetic process

[Term]
id: GO:0010557
name: positive regulation of macromolecule biosynthetic process
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb]
is_a: GO:0010556 ! regulation of macromolecule biosynthetic process
is_a: GO:0010604 ! positive regulation of macromolecule metabolic process
is_a: GO:0031328 ! positive regulation of cellular biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009059 ! macromolecule biosynthetic process
relationship: positively_regulates GO:0009059 ! macromolecule biosynthetic process

[Term]
id: GO:0010558
name: negative regulation of macromolecule biosynthetic process
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb]
is_a: GO:0010556 ! regulation of macromolecule biosynthetic process
is_a: GO:0010605 ! negative regulation of macromolecule metabolic process
is_a: GO:0031327 ! negative regulation of cellular biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009059 ! macromolecule biosynthetic process
relationship: negatively_regulates GO:0009059 ! macromolecule biosynthetic process

[Term]
id: GO:0010559
name: regulation of glycoprotein biosynthetic process
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb]
is_a: GO:0010556 ! regulation of macromolecule biosynthetic process
is_a: GO:1903018 ! regulation of glycoprotein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009101 ! glycoprotein biosynthetic process
relationship: regulates GO:0009101 ! glycoprotein biosynthetic process

[Term]
id: GO:0010560
name: positive regulation of glycoprotein biosynthetic process
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb]
is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process
is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process
is_a: GO:1903020 ! positive regulation of glycoprotein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009101 ! glycoprotein biosynthetic process
relationship: positively_regulates GO:0009101 ! glycoprotein biosynthetic process

[Term]
id: GO:0010561
name: negative regulation of glycoprotein biosynthetic process
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb]
is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process
is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process
is_a: GO:1903019 ! negative regulation of glycoprotein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009101 ! glycoprotein biosynthetic process
relationship: negatively_regulates GO:0009101 ! glycoprotein biosynthetic process

[Term]
id: GO:0010562
name: positive regulation of phosphorus metabolic process
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb]
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0051174 ! regulation of phosphorus metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006793 ! phosphorus metabolic process
relationship: positively_regulates GO:0006793 ! phosphorus metabolic process

[Term]
id: GO:0010563
name: negative regulation of phosphorus metabolic process
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb]
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0051174 ! regulation of phosphorus metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006793 ! phosphorus metabolic process
relationship: negatively_regulates GO:0006793 ! phosphorus metabolic process

[Term]
id: GO:0010564
name: regulation of cell cycle process
namespace: biological_process
def: "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb]
is_a: GO:0051726 ! regulation of cell cycle
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0022402 ! cell cycle process
relationship: regulates GO:0022402 ! cell cycle process

[Term]
id: GO:0010565
name: regulation of cellular ketone metabolic process
namespace: biological_process
def: "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:dph, GOC:tb]
is_a: GO:0031323 ! regulation of cellular metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042180 ! cellular ketone metabolic process
relationship: regulates GO:0042180 ! cellular ketone metabolic process

[Term]
id: GO:0010566
name: regulation of ketone biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells." [GOC:dph, GOC:tb]
is_a: GO:0010565 ! regulation of cellular ketone metabolic process
is_a: GO:0031326 ! regulation of cellular biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042181 ! ketone biosynthetic process
relationship: regulates GO:0042181 ! ketone biosynthetic process

[Term]
id: GO:0010567
name: regulation of ketone catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells." [GOC:dph, GOC:tb]
is_a: GO:0010565 ! regulation of cellular ketone metabolic process
is_a: GO:0031329 ! regulation of cellular catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042182 ! ketone catabolic process
relationship: regulates GO:0042182 ! ketone catabolic process

[Term]
id: GO:0010594
name: regulation of endothelial cell migration
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010632 ! regulation of epithelial cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0043542 ! endothelial cell migration
relationship: regulates GO:0043542 ! endothelial cell migration

[Term]
id: GO:0010595
name: positive regulation of endothelial cell migration
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010594 ! regulation of endothelial cell migration
is_a: GO:0010634 ! positive regulation of epithelial cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0043542 ! endothelial cell migration
relationship: positively_regulates GO:0043542 ! endothelial cell migration

[Term]
id: GO:0010596
name: negative regulation of endothelial cell migration
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010594 ! regulation of endothelial cell migration
is_a: GO:0010633 ! negative regulation of epithelial cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0043542 ! endothelial cell migration
relationship: negatively_regulates GO:0043542 ! endothelial cell migration

[Term]
id: GO:0010604
name: positive regulation of macromolecule metabolic process
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb]
is_a: GO:0009893 ! positive regulation of metabolic process
is_a: GO:0060255 ! regulation of macromolecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0043170 ! macromolecule metabolic process
relationship: positively_regulates GO:0043170 ! macromolecule metabolic process

[Term]
id: GO:0010605
name: negative regulation of macromolecule metabolic process
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb]
is_a: GO:0009892 ! negative regulation of metabolic process
is_a: GO:0060255 ! regulation of macromolecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0043170 ! macromolecule metabolic process
relationship: negatively_regulates GO:0043170 ! macromolecule metabolic process

[Term]
id: GO:0010608
name: post-transcriptional regulation of gene expression
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." [GOC:dph, GOC:tb]
synonym: "posttranscriptional regulation of gene expression" EXACT []
is_a: GO:0010468 ! regulation of gene expression

[Term]
id: GO:0010611
name: regulation of cardiac muscle hypertrophy
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:dph, GOC:tb]
is_a: GO:0014743 ! regulation of muscle hypertrophy
is_a: GO:0043502 ! regulation of muscle adaptation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003300 ! cardiac muscle hypertrophy
relationship: regulates GO:0003300 ! cardiac muscle hypertrophy

[Term]
id: GO:0010612
name: regulation of cardiac muscle adaptation
namespace: biological_process
def: "Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:dph, GOC:tb]
is_a: GO:0043502 ! regulation of muscle adaptation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014887 ! cardiac muscle adaptation
relationship: regulates GO:0014887 ! cardiac muscle adaptation

[Term]
id: GO:0010613
name: positive regulation of cardiac muscle hypertrophy
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy
is_a: GO:0014742 ! positive regulation of muscle hypertrophy
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003300 ! cardiac muscle hypertrophy
relationship: positively_regulates GO:0003300 ! cardiac muscle hypertrophy

[Term]
id: GO:0010614
name: negative regulation of cardiac muscle hypertrophy
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy
is_a: GO:0014741 ! negative regulation of muscle hypertrophy
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003300 ! cardiac muscle hypertrophy
relationship: negatively_regulates GO:0003300 ! cardiac muscle hypertrophy

[Term]
id: GO:0010615
name: positive regulation of cardiac muscle adaptation
namespace: biological_process
def: "Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010612 ! regulation of cardiac muscle adaptation
is_a: GO:0014744 ! positive regulation of muscle adaptation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014887 ! cardiac muscle adaptation
relationship: positively_regulates GO:0014887 ! cardiac muscle adaptation

[Term]
id: GO:0010616
name: negative regulation of cardiac muscle adaptation
namespace: biological_process
def: "Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010612 ! regulation of cardiac muscle adaptation
is_a: GO:0014745 ! negative regulation of muscle adaptation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014887 ! cardiac muscle adaptation
relationship: negatively_regulates GO:0014887 ! cardiac muscle adaptation

[Term]
id: GO:0010623
name: programmed cell death involved in cell development
namespace: biological_process
def: "The activation of endogenous cellular processes that result in the death of a cell as part of its development." [GOC:dph, GOC:mtg_apoptosis, GOC:tb]
comment: This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure.
synonym: "developmental programmed cell death" BROAD []
synonym: "programmed cell death involved in development" BROAD []
is_a: GO:0012501 ! programmed cell death
is_a: GO:0048869 ! cellular developmental process
intersection_of: GO:0012501 ! programmed cell death
intersection_of: part_of GO:0048468 ! cell development
relationship: part_of GO:0048468 ! cell development

[Term]
id: GO:0010628
name: positive regulation of gene expression
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018]
is_a: GO:0010468 ! regulation of gene expression
is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010467 ! gene expression
relationship: positively_regulates GO:0010467 ! gene expression
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI

[Term]
id: GO:0010629
name: negative regulation of gene expression
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018]
comment: This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation.
synonym: "gene silencing" RELATED []
is_a: GO:0010468 ! regulation of gene expression
is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010467 ! gene expression
relationship: negatively_regulates GO:0010467 ! gene expression
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI

[Term]
id: GO:0010631
name: epithelial cell migration
namespace: biological_process
def: "The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:ascb_2009, GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0001667 ! ameboidal-type cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000066 ! epithelial cell
relationship: part_of GO:0090132 ! epithelium migration
relationship: results_in_movement_of CL:0000066 ! epithelial cell

[Term]
id: GO:0010632
name: regulation of epithelial cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0030334 ! regulation of cell migration
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010631 ! epithelial cell migration
relationship: regulates GO:0010631 ! epithelial cell migration

[Term]
id: GO:0010633
name: negative regulation of epithelial cell migration
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010632 ! regulation of epithelial cell migration
is_a: GO:0030336 ! negative regulation of cell migration
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010631 ! epithelial cell migration
relationship: negatively_regulates GO:0010631 ! epithelial cell migration

[Term]
id: GO:0010634
name: positive regulation of epithelial cell migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010632 ! regulation of epithelial cell migration
is_a: GO:0030335 ! positive regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010631 ! epithelial cell migration
relationship: positively_regulates GO:0010631 ! epithelial cell migration

[Term]
id: GO:0010638
name: positive regulation of organelle organization
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb]
synonym: "positive regulation of organelle organisation" EXACT [GOC:mah]
synonym: "positive regulation of organelle organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0033043 ! regulation of organelle organization
is_a: GO:0051130 ! positive regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006996 ! organelle organization
relationship: positively_regulates GO:0006996 ! organelle organization

[Term]
id: GO:0010639
name: negative regulation of organelle organization
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb]
synonym: "negative regulation of organelle organisation" EXACT [GOC:mah]
synonym: "negative regulation of organelle organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0033043 ! regulation of organelle organization
is_a: GO:0051129 ! negative regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006996 ! organelle organization
relationship: negatively_regulates GO:0006996 ! organelle organization

[Term]
id: GO:0010646
name: regulation of cell communication
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007154 ! cell communication
relationship: regulates GO:0007154 ! cell communication

[Term]
id: GO:0010647
name: positive regulation of cell communication
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007154 ! cell communication
relationship: positively_regulates GO:0007154 ! cell communication

[Term]
id: GO:0010648
name: negative regulation of cell communication
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007154 ! cell communication
relationship: negatively_regulates GO:0007154 ! cell communication

[Term]
id: GO:0010656
name: negative regulation of muscle cell apoptotic process
namespace: biological_process
def: "Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb]
synonym: "negative regulation of muscle cell apoptosis" NARROW []
is_a: GO:0010660 ! regulation of muscle cell apoptotic process
is_a: GO:0043066 ! negative regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010657 ! muscle cell apoptotic process
relationship: negatively_regulates GO:0010657 ! muscle cell apoptotic process

[Term]
id: GO:0010657
name: muscle cell apoptotic process
namespace: biological_process
def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle." [CL:0000187, GOC:dph, GOC:mtg_apoptosis, GOC:tb]
synonym: "muscle cell apoptosis" NARROW []
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000187 ! muscle cell
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: occurs_in CL:0000187 ! muscle cell
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa

[Term]
id: GO:0010658
name: striated muscle cell apoptotic process
namespace: biological_process
def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations." [CL:0000737, GOC:dph, GOC:mtg_apoptosis, GOC:tb]
synonym: "striated muscle cell apoptosis" NARROW []
is_a: GO:0010657 ! muscle cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000737 ! striated muscle cell
relationship: occurs_in CL:0000737 ! striated muscle cell

[Term]
id: GO:0010659
name: cardiac muscle cell apoptotic process
namespace: biological_process
def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [CL:0000746, GOC:dph, GOC:mtg_apoptosis, GOC:tb]
synonym: "cardiac muscle cell apoptosis" NARROW []
is_a: GO:0010658 ! striated muscle cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000746 ! cardiac muscle cell
relationship: occurs_in CL:0000746 ! cardiac muscle cell

[Term]
id: GO:0010660
name: regulation of muscle cell apoptotic process
namespace: biological_process
def: "Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb]
synonym: "regulation of muscle cell apoptosis" NARROW []
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010657 ! muscle cell apoptotic process
relationship: regulates GO:0010657 ! muscle cell apoptotic process

[Term]
id: GO:0010661
name: positive regulation of muscle cell apoptotic process
namespace: biological_process
def: "Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb]
synonym: "positive regulation of muscle cell apoptosis" NARROW []
is_a: GO:0010660 ! regulation of muscle cell apoptotic process
is_a: GO:0043065 ! positive regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010657 ! muscle cell apoptotic process
relationship: positively_regulates GO:0010657 ! muscle cell apoptotic process

[Term]
id: GO:0010662
name: regulation of striated muscle cell apoptotic process
namespace: biological_process
def: "Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb]
synonym: "regulation of striated muscle cell apoptosis" NARROW []
is_a: GO:0010660 ! regulation of muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010658 ! striated muscle cell apoptotic process
relationship: regulates GO:0010658 ! striated muscle cell apoptotic process

[Term]
id: GO:0010663
name: positive regulation of striated muscle cell apoptotic process
namespace: biological_process
def: "Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb]
synonym: "positive regulation of striated muscle cell apoptosis" NARROW []
is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process
is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010658 ! striated muscle cell apoptotic process
relationship: positively_regulates GO:0010658 ! striated muscle cell apoptotic process

[Term]
id: GO:0010664
name: negative regulation of striated muscle cell apoptotic process
namespace: biological_process
def: "Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb]
synonym: "down regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb]
synonym: "down-regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb]
synonym: "downregulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb]
synonym: "inhibition of striated muscle cell apoptosis" NARROW [GOC:dph, GOC:rl, GOC:tb]
synonym: "negative regulation of striated muscle cell apoptosis" NARROW []
is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process
is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010658 ! striated muscle cell apoptotic process
relationship: negatively_regulates GO:0010658 ! striated muscle cell apoptotic process

[Term]
id: GO:0010665
name: regulation of cardiac muscle cell apoptotic process
namespace: biological_process
def: "Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb]
synonym: "regulation of cardiac muscle cell apoptosis" NARROW []
is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010659 ! cardiac muscle cell apoptotic process
relationship: regulates GO:0010659 ! cardiac muscle cell apoptotic process

[Term]
id: GO:0010666
name: positive regulation of cardiac muscle cell apoptotic process
namespace: biological_process
def: "Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb]
synonym: "positive regulation of cardiac muscle cell apoptosis" NARROW []
is_a: GO:0010663 ! positive regulation of striated muscle cell apoptotic process
is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010659 ! cardiac muscle cell apoptotic process
relationship: positively_regulates GO:0010659 ! cardiac muscle cell apoptotic process

[Term]
id: GO:0010667
name: negative regulation of cardiac muscle cell apoptotic process
namespace: biological_process
def: "Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb]
synonym: "down regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb]
synonym: "down-regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb]
synonym: "downregulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb]
synonym: "inhibition of cardiac muscle cell apoptosis" NARROW [GOC:dph, GOC:rl, GOC:tb]
synonym: "negative regulation of cardiac muscle cell apoptosis" NARROW []
is_a: GO:0010664 ! negative regulation of striated muscle cell apoptotic process
is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010659 ! cardiac muscle cell apoptotic process
relationship: negatively_regulates GO:0010659 ! cardiac muscle cell apoptotic process

[Term]
id: GO:0010668
name: ectodermal cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:tb]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000221 ! ectodermal cell
relationship: part_of GO:0007398 ! ectoderm development
relationship: results_in_acquisition_of_features_of CL:0000221 ! ectodermal cell

[Term]
id: GO:0010700
name: negative regulation of norepinephrine secretion
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb]
is_a: GO:0014061 ! regulation of norepinephrine secretion
is_a: GO:0033604 ! negative regulation of catecholamine secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048243 ! norepinephrine secretion
relationship: negatively_regulates GO:0048243 ! norepinephrine secretion

[Term]
id: GO:0010701
name: positive regulation of norepinephrine secretion
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb]
is_a: GO:0014061 ! regulation of norepinephrine secretion
is_a: GO:0033605 ! positive regulation of catecholamine secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048243 ! norepinephrine secretion
relationship: positively_regulates GO:0048243 ! norepinephrine secretion

[Term]
id: GO:0010710
name: regulation of collagen catabolic process
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb]
synonym: "regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb]
synonym: "regulation of collagen degradation" EXACT [GOC:dph, GOC:tb]
is_a: GO:0009894 ! regulation of catabolic process
is_a: GO:0010712 ! regulation of collagen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030574 ! collagen catabolic process
relationship: regulates GO:0030574 ! collagen catabolic process

[Term]
id: GO:0010711
name: negative regulation of collagen catabolic process
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "down regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb]
synonym: "down-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb]
synonym: "downregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb]
synonym: "inhibition of collagen catabolic process" NARROW [GOC:dph, GOC:tb]
synonym: "negative regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb]
synonym: "negative regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb]
synonym: "negative regulation of collagen degradation" EXACT [GOC:dph, GOC:tb]
is_a: GO:0009895 ! negative regulation of catabolic process
is_a: GO:0010710 ! regulation of collagen catabolic process
is_a: GO:0010713 ! negative regulation of collagen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030574 ! collagen catabolic process
relationship: negatively_regulates GO:0030574 ! collagen catabolic process

[Term]
id: GO:0010712
name: regulation of collagen metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb]
synonym: "regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb]
is_a: GO:0019222 ! regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032963 ! collagen metabolic process
relationship: regulates GO:0032963 ! collagen metabolic process

[Term]
id: GO:0010713
name: negative regulation of collagen metabolic process
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb]
is_a: GO:0009892 ! negative regulation of metabolic process
is_a: GO:0010712 ! regulation of collagen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032963 ! collagen metabolic process
relationship: negatively_regulates GO:0032963 ! collagen metabolic process

[Term]
id: GO:0010714
name: positive regulation of collagen metabolic process
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb]
synonym: "positive regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb]
is_a: GO:0009893 ! positive regulation of metabolic process
is_a: GO:0010712 ! regulation of collagen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032963 ! collagen metabolic process
relationship: positively_regulates GO:0032963 ! collagen metabolic process

[Term]
id: GO:0010715
name: regulation of extracellular matrix disassembly
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb]
synonym: "regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb]
is_a: GO:1903053 ! regulation of extracellular matrix organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0022617 ! extracellular matrix disassembly
relationship: regulates GO:0022617 ! extracellular matrix disassembly

[Term]
id: GO:0010716
name: negative regulation of extracellular matrix disassembly
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "down regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb]
synonym: "down-regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb]
synonym: "downregulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb]
synonym: "inhibition of extracellular matrix disassembly" NARROW [GOC:dph, GOC:tb]
synonym: "negative regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb]
synonym: "negative regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb]
is_a: GO:0010715 ! regulation of extracellular matrix disassembly
is_a: GO:1903054 ! negative regulation of extracellular matrix organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0022617 ! extracellular matrix disassembly
relationship: negatively_regulates GO:0022617 ! extracellular matrix disassembly

[Term]
id: GO:0010717
name: regulation of epithelial to mesenchymal transition
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001837 ! epithelial to mesenchymal transition
relationship: regulates GO:0001837 ! epithelial to mesenchymal transition

[Term]
id: GO:0010718
name: positive regulation of epithelial to mesenchymal transition
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001837 ! epithelial to mesenchymal transition
relationship: positively_regulates GO:0001837 ! epithelial to mesenchymal transition

[Term]
id: GO:0010719
name: negative regulation of epithelial to mesenchymal transition
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001837 ! epithelial to mesenchymal transition
relationship: negatively_regulates GO:0001837 ! epithelial to mesenchymal transition

[Term]
id: GO:0010720
name: positive regulation of cell development
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048468 ! cell development
relationship: positively_regulates GO:0048468 ! cell development

[Term]
id: GO:0010721
name: negative regulation of cell development
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048468 ! cell development
relationship: negatively_regulates GO:0048468 ! cell development

[Term]
id: GO:0010761
name: fibroblast migration
namespace: biological_process
def: "Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "fibroblast cell migration" EXACT [GOC:dph]
is_a: GO:0001667 ! ameboidal-type cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000057 ! fibroblast
relationship: results_in_movement_of CL:0000057 ! fibroblast

[Term]
id: GO:0010762
name: regulation of fibroblast migration
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb]
synonym: "regulation of fibroblast cell migration" EXACT [GOC:dph]
is_a: GO:0030334 ! regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010761 ! fibroblast migration
relationship: regulates GO:0010761 ! fibroblast migration

[Term]
id: GO:0010763
name: positive regulation of fibroblast migration
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "positive regulation of fibroblast cell migration" EXACT [GOC:dph]
is_a: GO:0010762 ! regulation of fibroblast migration
is_a: GO:0030335 ! positive regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010761 ! fibroblast migration
relationship: positively_regulates GO:0010761 ! fibroblast migration

[Term]
id: GO:0010764
name: negative regulation of fibroblast migration
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb]
synonym: "negative regulation of fibroblast cell migration" EXACT [GOC:dph]
is_a: GO:0010762 ! regulation of fibroblast migration
is_a: GO:0030336 ! negative regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010761 ! fibroblast migration
relationship: negatively_regulates GO:0010761 ! fibroblast migration

[Term]
id: GO:0010765
name: positive regulation of sodium ion transport
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb]
is_a: GO:0002028 ! regulation of sodium ion transport
is_a: GO:0043270 ! positive regulation of monoatomic ion transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006814 ! sodium ion transport
relationship: positively_regulates GO:0006814 ! sodium ion transport

[Term]
id: GO:0010766
name: negative regulation of sodium ion transport
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb]
is_a: GO:0002028 ! regulation of sodium ion transport
is_a: GO:0043271 ! negative regulation of monoatomic ion transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006814 ! sodium ion transport
relationship: negatively_regulates GO:0006814 ! sodium ion transport

[Term]
id: GO:0010770
name: positive regulation of cell morphogenesis
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb]
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0022604 ! regulation of cell morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0000902 ! cell morphogenesis
relationship: positively_regulates GO:0000902 ! cell morphogenesis
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24299" xsd:anyURI

[Term]
id: GO:0010771
name: negative regulation of cell morphogenesis
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb]
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0022604 ! regulation of cell morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0000902 ! cell morphogenesis
relationship: negatively_regulates GO:0000902 ! cell morphogenesis
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24299" xsd:anyURI

[Term]
id: GO:0010817
name: regulation of hormone levels
namespace: biological_process
def: "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." [GOC:BHF, GOC:dph, GOC:tb]

[Term]
id: GO:0010827
name: regulation of glucose transmembrane transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb]
synonym: "regulation of glucose transport" RELATED []
is_a: GO:0034762 ! regulation of transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1904659 ! glucose transmembrane transport
relationship: regulates GO:1904659 ! glucose transmembrane transport

[Term]
id: GO:0010828
name: positive regulation of glucose transmembrane transport
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "positive regulation of glucose transport" RELATED []
is_a: GO:0010827 ! regulation of glucose transmembrane transport
is_a: GO:0034764 ! positive regulation of transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1904659 ! glucose transmembrane transport
relationship: positively_regulates GO:1904659 ! glucose transmembrane transport

[Term]
id: GO:0010829
name: negative regulation of glucose transmembrane transport
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "negative regulation of glucose transport" RELATED []
is_a: GO:0010827 ! regulation of glucose transmembrane transport
is_a: GO:0034763 ! negative regulation of transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1904659 ! glucose transmembrane transport
relationship: negatively_regulates GO:1904659 ! glucose transmembrane transport

[Term]
id: GO:0010830
name: regulation of myotube differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb]
is_a: GO:0051153 ! regulation of striated muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014902 ! myotube differentiation
relationship: regulates GO:0014902 ! myotube differentiation

[Term]
id: GO:0010831
name: positive regulation of myotube differentiation
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb]
is_a: GO:0010830 ! regulation of myotube differentiation
is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014902 ! myotube differentiation
relationship: positively_regulates GO:0014902 ! myotube differentiation

[Term]
id: GO:0010832
name: negative regulation of myotube differentiation
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb]
is_a: GO:0010830 ! regulation of myotube differentiation
is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014902 ! myotube differentiation
relationship: negatively_regulates GO:0014902 ! myotube differentiation

[Term]
id: GO:0010842
name: retina layer formation
namespace: biological_process
def: "The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia." [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:1270266]
synonym: "retinal lamination" EXACT [GOC:dph, GOC:tb]
synonym: "retinal layer formation" EXACT [GOC:dph, GOC:tb]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001781 ! layer of retina
relationship: part_of GO:0003407 ! neural retina development
relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye
relationship: results_in_formation_of_anatomical_entity UBERON:0001781 ! layer of retina

[Term]
id: GO:0010876
name: lipid localization
namespace: biological_process
def: "Any process in which a lipid is transported to, or maintained in, a specific location." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "lipid localisation" EXACT [GOC:mah]
is_a: GO:0033036 ! macromolecule localization
intersection_of: GO:0033036 ! macromolecule localization
intersection_of: has_primary_input CHEBI:18059 ! lipid
relationship: has_primary_input CHEBI:18059 ! lipid

[Term]
id: GO:0010893
name: positive regulation of steroid biosynthetic process
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:tb]
is_a: GO:0045940 ! positive regulation of steroid metabolic process
is_a: GO:0046889 ! positive regulation of lipid biosynthetic process
is_a: GO:0050810 ! regulation of steroid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006694 ! steroid biosynthetic process
relationship: positively_regulates GO:0006694 ! steroid biosynthetic process

[Term]
id: GO:0010894
name: negative regulation of steroid biosynthetic process
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:BHF, GOC:tb]
is_a: GO:0045939 ! negative regulation of steroid metabolic process
is_a: GO:0050810 ! regulation of steroid biosynthetic process
is_a: GO:0051055 ! negative regulation of lipid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006694 ! steroid biosynthetic process
relationship: negatively_regulates GO:0006694 ! steroid biosynthetic process

[Term]
id: GO:0010906
name: regulation of glucose metabolic process
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb]
synonym: "regulation of glucose metabolism" EXACT [GOC:tb]
is_a: GO:0006109 ! regulation of carbohydrate metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006006 ! glucose metabolic process
relationship: regulates GO:0006006 ! glucose metabolic process

[Term]
id: GO:0010907
name: positive regulation of glucose metabolic process
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb]
synonym: "positive regulation of glucose metabolism" EXACT [GOC:tb]
is_a: GO:0010906 ! regulation of glucose metabolic process
is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006006 ! glucose metabolic process
relationship: positively_regulates GO:0006006 ! glucose metabolic process

[Term]
id: GO:0010927
name: cellular component assembly involved in morphogenesis
namespace: biological_process
def: "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." [GOC:dph, GOC:tb]
is_a: GO:0022607 ! cellular component assembly
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis
relationship: part_of GO:0032989 ! cellular anatomical entity morphogenesis

[Term]
id: GO:0010937
name: regulation of cytoplasmic microtubule depolymerization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization." [GOC:dph, GOC:tb]
is_a: GO:0031114 ! regulation of microtubule depolymerization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010938 ! cytoplasmic microtubule depolymerization
relationship: regulates GO:0010938 ! cytoplasmic microtubule depolymerization

[Term]
id: GO:0010938
name: cytoplasmic microtubule depolymerization
namespace: biological_process
def: "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule." [GOC:dph, GOC:tb]
is_a: GO:0007019 ! microtubule depolymerization
is_a: GO:0031122 ! cytoplasmic microtubule organization
intersection_of: GO:0007019 ! microtubule depolymerization
intersection_of: occurs_in GO:0005737 ! cytoplasm
relationship: occurs_in GO:0005737 ! cytoplasm

[Term]
id: GO:0010948
name: negative regulation of cell cycle process
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb]
is_a: GO:0010564 ! regulation of cell cycle process
is_a: GO:0045786 ! negative regulation of cell cycle
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0022402 ! cell cycle process
relationship: negatively_regulates GO:0022402 ! cell cycle process
created_by: tb
creation_date: 2009-04-27T09:53:22Z

[Term]
id: GO:0010959
name: regulation of metal ion transport
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb]
is_a: GO:0043269 ! regulation of monoatomic ion transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030001 ! metal ion transport
relationship: regulates GO:0030001 ! metal ion transport
created_by: tb
creation_date: 2009-05-06T11:40:55Z

[Term]
id: GO:0010962
name: regulation of glucan biosynthetic process
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:dph, GOC:tb]
is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009250 ! glucan biosynthetic process
relationship: regulates GO:0009250 ! glucan biosynthetic process
created_by: tb
creation_date: 2009-05-11T12:17:53Z

[Term]
id: GO:0010966
name: regulation of phosphate transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb]
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006817 ! phosphate ion transport
relationship: regulates GO:0006817 ! phosphate ion transport
created_by: tb
creation_date: 2009-05-20T11:42:50Z

[Term]
id: GO:0010968
name: regulation of microtubule nucleation
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb]
is_a: GO:0031113 ! regulation of microtubule polymerization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007020 ! microtubule nucleation
relationship: regulates GO:0007020 ! microtubule nucleation
created_by: tb
creation_date: 2009-05-20T11:51:21Z

[Term]
id: GO:0010970
name: transport along microtubule
namespace: biological_process
def: "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity." [GOC:dph, GOC:mah, GOC:tb]
synonym: "establishment of localization by movement along microtubule" EXACT [GOC:dph]
synonym: "microtubule-based transport" BROAD []
synonym: "movement along microtubule" EXACT []
is_a: GO:0007018 ! microtubule-based movement
is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport
is_a: GO:0099111 ! microtubule-based transport
intersection_of: GO:0006810 ! transport
intersection_of: results_in_transport_along GO:0005874 ! microtubule
relationship: results_in_transport_along GO:0005874 ! microtubule
created_by: tb
creation_date: 2009-05-27T10:56:08Z

[Term]
id: GO:0010975
name: regulation of neuron projection development
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb]
synonym: "regulation of neurite biosynthesis" NARROW [GOC:mah]
synonym: "regulation of neurite development" NARROW [GOC:mah]
synonym: "regulation of neurite formation" NARROW [GOC:mah]
synonym: "regulation of neurite growth" NARROW [GOC:mah]
is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0031175 ! neuron projection development
relationship: regulates GO:0031175 ! neuron projection development
created_by: tb
creation_date: 2009-06-01T10:44:45Z

[Term]
id: GO:0010976
name: positive regulation of neuron projection development
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb]
synonym: "positive regulation of neurite biosynthesis" NARROW [GOC:mah]
synonym: "positive regulation of neurite development" NARROW [GOC:mah]
synonym: "positive regulation of neurite formation" NARROW [GOC:mah]
synonym: "positive regulation of neurite growth" NARROW [GOC:mah]
is_a: GO:0010975 ! regulation of neuron projection development
is_a: GO:0031346 ! positive regulation of cell projection organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0031175 ! neuron projection development
relationship: positively_regulates GO:0031175 ! neuron projection development
created_by: tb
creation_date: 2009-06-01T10:46:44Z

[Term]
id: GO:0010977
name: negative regulation of neuron projection development
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb]
synonym: "growth cone collapse" RELATED [GOC:pr]
synonym: "negative regulation of neurite biosynthesis" NARROW [GOC:mah]
synonym: "negative regulation of neurite development" NARROW [GOC:mah]
synonym: "negative regulation of neurite formation" NARROW [GOC:mah]
synonym: "negative regulation of neurite growth" NARROW [GOC:mah]
is_a: GO:0010975 ! regulation of neuron projection development
is_a: GO:0031345 ! negative regulation of cell projection organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0031175 ! neuron projection development
relationship: negatively_regulates GO:0031175 ! neuron projection development
created_by: tb
creation_date: 2009-06-01T10:47:42Z

[Term]
id: GO:0012501
name: programmed cell death
namespace: biological_process
alt_id: GO:0016244
def: "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." [GOC:lr, GOC:mtg_apoptosis]
comment: Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children.
subset: goslim_agr
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_mouse
subset: goslim_plant
subset: goslim_prokaryote
synonym: "caspase-independent apoptosis" RELATED []
synonym: "caspase-independent cell death" NARROW []
synonym: "non-apoptotic programmed cell death" NARROW []
synonym: "nonapoptotic programmed cell death" NARROW []
synonym: "PCD" RELATED []
synonym: "RCD" RELATED []
synonym: "regulated cell death" BROAD []
xref: Wikipedia:Programmed_cell_death
is_a: GO:0008219 ! cell death
intersection_of: GO:0008219 ! cell death
intersection_of: starts_with GO:0007165 ! signal transduction
relationship: starts_with GO:0007165 ! signal transduction
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24835" xsd:anyURI

[Term]
id: GO:0012505
name: endomembrane system
namespace: cellular_component
def: "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." [GOC:lh]
subset: goslim_candida
subset: goslim_flybase_ribbon
subset: goslim_yeast
xref: Wikipedia:Endomembrane_system
is_a: GO:0110165 ! cellular anatomical entity
relationship: has_part GO:0005773 ! vacuole
relationship: has_part GO:0005886 ! plasma membrane
relationship: part_of CL:0000000 ! cell

[Term]
id: GO:0012506
name: vesicle membrane
namespace: cellular_component
def: "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." [GOC:mah, GOC:vesicle]
xref: NIF_Subcellular:sao1153182838
is_a: GO:0031090 ! organelle membrane
intersection_of: GO:0016020 ! membrane
intersection_of: part_of GO:0031982 ! vesicle
relationship: part_of GO:0031982 ! vesicle

[Term]
id: GO:0014009
name: glial cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others." [GOC:ef, ISBN:0878932585]
synonym: "glia proliferation" EXACT []
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000125 ! glial cell
relationship: acts_on_population_of CL:0000125 ! glial cell
relationship: part_of GO:0042063 ! gliogenesis

[Term]
id: GO:0014013
name: regulation of gliogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef]
is_a: GO:0050767 ! regulation of neurogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042063 ! gliogenesis
relationship: regulates GO:0042063 ! gliogenesis

[Term]
id: GO:0014014
name: negative regulation of gliogenesis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef]
synonym: "down regulation of gliogenesis" EXACT []
synonym: "down-regulation of gliogenesis" EXACT []
synonym: "downregulation of gliogenesis" EXACT []
synonym: "inhibition of gliogenesis" NARROW []
is_a: GO:0014013 ! regulation of gliogenesis
is_a: GO:0050768 ! negative regulation of neurogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042063 ! gliogenesis
relationship: negatively_regulates GO:0042063 ! gliogenesis

[Term]
id: GO:0014015
name: positive regulation of gliogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef]
synonym: "activation of gliogenesis" NARROW []
synonym: "stimulation of gliogenesis" NARROW []
synonym: "up regulation of gliogenesis" EXACT []
synonym: "up-regulation of gliogenesis" EXACT []
synonym: "upregulation of gliogenesis" EXACT []
is_a: GO:0014013 ! regulation of gliogenesis
is_a: GO:0050769 ! positive regulation of neurogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0042063 ! gliogenesis
relationship: positively_regulates GO:0042063 ! gliogenesis

[Term]
id: GO:0014016
name: neuroblast differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts." [GOC:ef, ISBN:0878932585]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: part_of GO:0048699 ! generation of neurons
relationship: results_in_acquisition_of_features_of CL:0000031 ! neuroblast (sensu Vertebrata)

[Term]
id: GO:0014019
name: neuroblast development
namespace: biological_process
def: "The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron." [GOC:ef, ISBN:0878932585]
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: part_of GO:0014016 ! neuroblast differentiation
relationship: results_in_development_of CL:0000031 ! neuroblast (sensu Vertebrata)

[Term]
id: GO:0014020
name: primary neural tube formation
namespace: biological_process
alt_id: GO:0014024
def: "The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube." [GOC:ef, ISBN:0878932585, PMID:15327780]
synonym: "neural rod cavitation" RELATED []
synonym: "primary neural tube morphogenesis" EXACT [GOC:dph]
synonym: "primary neurulation" EXACT []
is_a: GO:0001838 ! embryonic epithelial tube formation
relationship: part_of GO:0001841 ! neural tube formation

[Term]
id: GO:0014023
name: neural rod formation
namespace: biological_process
def: "The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005068 ! neural rod
relationship: in_taxon NCBITaxon:32443 {all_only="true"} ! Teleostei
relationship: only_in_taxon NCBITaxon:32443 ! Teleostei
relationship: part_of GO:0014020 ! primary neural tube formation
relationship: results_in_formation_of_anatomical_entity UBERON:0005068 ! neural rod

[Term]
id: GO:0014025
name: neural keel formation
namespace: biological_process
def: "The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0007135 ! neural keel
relationship: part_of GO:0014023 ! neural rod formation
relationship: results_in_formation_of_anatomical_entity UBERON:0007135 ! neural keel

[Term]
id: GO:0014028
name: notochord formation
namespace: biological_process
def: "The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column." [GOC:dh, GOC:ef]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002328 ! notochord
relationship: part_of GO:0007399 ! nervous system development
relationship: part_of GO:0048570 ! notochord morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002328 ! notochord

[Term]
id: GO:0014029
name: neural crest formation
namespace: biological_process
def: "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:dh, GOC:ef]
is_a: GO:0001837 ! epithelial to mesenchymal transition
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002342 ! neural crest
relationship: part_of GO:0043009 ! chordate embryonic development
relationship: results_in_formation_of_anatomical_entity UBERON:0002342 ! neural crest

[Term]
id: GO:0014031
name: mesenchymal cell development
namespace: biological_process
def: "The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef]
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0008019 ! mesenchymal cell
relationship: part_of GO:0048762 ! mesenchymal cell differentiation
relationship: results_in_development_of CL:0008019 ! mesenchymal cell

[Term]
id: GO:0014032
name: neural crest cell development
namespace: biological_process
def: "The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef]
is_a: GO:0048864 ! stem cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0011012 ! neural crest cell
relationship: part_of GO:0014033 ! neural crest cell differentiation
relationship: results_in_development_of CL:0011012 ! neural crest cell

[Term]
id: GO:0014033
name: neural crest cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell." [GOC:dh, GOC:ef]
is_a: GO:0048762 ! mesenchymal cell differentiation
is_a: GO:0048863 ! stem cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000333 ! migratory neural crest cell
relationship: results_in_acquisition_of_features_of CL:0000333 ! migratory neural crest cell

[Term]
id: GO:0014041
name: regulation of neuron maturation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." [GOC:ef]
is_a: GO:0045664 ! regulation of neuron differentiation
is_a: GO:1903429 ! regulation of cell maturation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042551 ! neuron maturation
relationship: regulates GO:0042551 ! neuron maturation

[Term]
id: GO:0014042
name: positive regulation of neuron maturation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuron maturation." [GOC:ef]
synonym: "activation of neuron maturation" NARROW []
synonym: "stimulation of neuron maturation" NARROW []
synonym: "up regulation of neuron maturation" EXACT []
synonym: "up-regulation of neuron maturation" EXACT []
synonym: "upregulation of neuron maturation" EXACT []
is_a: GO:0014041 ! regulation of neuron maturation
is_a: GO:1903431 ! positive regulation of cell maturation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0042551 ! neuron maturation
relationship: positively_regulates GO:0042551 ! neuron maturation

[Term]
id: GO:0014043
name: negative regulation of neuron maturation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation." [GOC:ef]
synonym: "down regulation of neuron maturation" EXACT []
synonym: "down-regulation of neuron maturation" EXACT []
synonym: "downregulation of neuron maturation" EXACT []
synonym: "inhibition of neuron maturation" NARROW []
is_a: GO:0014041 ! regulation of neuron maturation
is_a: GO:1903430 ! negative regulation of cell maturation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042551 ! neuron maturation
relationship: negatively_regulates GO:0042551 ! neuron maturation

[Term]
id: GO:0014055
name: acetylcholine secretion, neurotransmission
namespace: biological_process
def: "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)." [GOC:ef]
is_a: GO:0007269 ! neurotransmitter secretion
is_a: GO:0061526 ! acetylcholine secretion
intersection_of: GO:0061526 ! acetylcholine secretion
intersection_of: part_of GO:0007271 ! synaptic transmission, cholinergic
relationship: part_of GO:0007271 ! synaptic transmission, cholinergic

[Term]
id: GO:0014056
name: regulation of acetylcholine secretion, neurotransmission
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef]
is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic
is_a: GO:0046928 ! regulation of neurotransmitter secretion
is_a: GO:0051952 ! regulation of amine transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014055 ! acetylcholine secretion, neurotransmission
relationship: regulates GO:0014055 ! acetylcholine secretion, neurotransmission

[Term]
id: GO:0014057
name: positive regulation of acetylcholine secretion, neurotransmission
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef]
synonym: "activation of acetylcholine secretion" NARROW []
synonym: "stimulation of acetylcholine secretion" NARROW []
synonym: "up regulation of acetylcholine secretion" EXACT []
synonym: "up-regulation of acetylcholine secretion" EXACT []
synonym: "upregulation of acetylcholine secretion" EXACT []
is_a: GO:0001956 ! positive regulation of neurotransmitter secretion
is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission
is_a: GO:0032224 ! positive regulation of synaptic transmission, cholinergic
is_a: GO:0051954 ! positive regulation of amine transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission
relationship: positively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission

[Term]
id: GO:0014058
name: negative regulation of acetylcholine secretion, neurotransmission
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef]
synonym: "down regulation of acetylcholine secretion" EXACT []
synonym: "down-regulation of acetylcholine secretion" EXACT []
synonym: "downregulation of acetylcholine secretion" EXACT []
synonym: "inhibition of acetylcholine secretion" NARROW []
is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission
is_a: GO:0032223 ! negative regulation of synaptic transmission, cholinergic
is_a: GO:0046929 ! negative regulation of neurotransmitter secretion
is_a: GO:0051953 ! negative regulation of amine transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission
relationship: negatively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission

[Term]
id: GO:0014061
name: regulation of norepinephrine secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine." [GOC:ef]
synonym: "regulation of noradrenaline secretion" EXACT []
is_a: GO:0050433 ! regulation of catecholamine secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048243 ! norepinephrine secretion
relationship: regulates GO:0048243 ! norepinephrine secretion

[Term]
id: GO:0014062
name: regulation of serotonin secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the regulated release of serotonin." [GOC:ef]
synonym: "regulation of serotonin release" RELATED [GOC:tb]
is_a: GO:0043269 ! regulation of monoatomic ion transport
is_a: GO:1903530 ! regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001820 ! serotonin secretion
relationship: regulates GO:0001820 ! serotonin secretion

[Term]
id: GO:0014063
name: negative regulation of serotonin secretion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin." [GOC:ef]
synonym: "down regulation of serotonin secretion" EXACT []
synonym: "down-regulation of serotonin secretion" EXACT []
synonym: "downregulation of serotonin secretion" EXACT []
synonym: "inhibition of serotonin secretion" NARROW []
synonym: "positive regulation of serotonin release" RELATED [GOC:tb]
is_a: GO:0014062 ! regulation of serotonin secretion
is_a: GO:0043271 ! negative regulation of monoatomic ion transport
is_a: GO:1903531 ! negative regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001820 ! serotonin secretion
relationship: negatively_regulates GO:0001820 ! serotonin secretion

[Term]
id: GO:0014064
name: positive regulation of serotonin secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin." [GOC:ef]
synonym: "activation of serotonin secretion" NARROW []
synonym: "positive regulation of serotonin release" RELATED [GOC:tb]
synonym: "stimulation of serotonin secretion" NARROW []
synonym: "up regulation of serotonin secretion" EXACT []
synonym: "up-regulation of serotonin secretion" EXACT []
synonym: "upregulation of serotonin secretion" EXACT []
is_a: GO:0014062 ! regulation of serotonin secretion
is_a: GO:0043270 ! positive regulation of monoatomic ion transport
is_a: GO:1903532 ! positive regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001820 ! serotonin secretion
relationship: positively_regulates GO:0001820 ! serotonin secretion

[Term]
id: GO:0014070
name: response to organic cyclic compound
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." [GOC:ef]
synonym: "response to organic cyclic substance" EXACT [GOC:mah]
is_a: GO:0010033 ! response to organic substance
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:33832 ! organic cyclic compound
relationship: has_primary_input CHEBI:33832 ! organic cyclic compound

[Term]
id: GO:0014075
name: response to amine
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [GOC:ef]
synonym: "response to amine stimulus" EXACT [GOC:dos]
is_a: GO:0010243 ! response to organonitrogen compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:32952 ! amine
relationship: has_primary_input CHEBI:32952 ! amine

[Term]
id: GO:0014706
name: striated muscle tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells." [CL:0000737, GOC:dph, GOC:mtg_muscle]
is_a: GO:0060537 ! muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002036 ! striated muscle tissue
relationship: results_in_development_of UBERON:0002036 ! striated muscle tissue

[Term]
id: GO:0014733
name: regulation of skeletal muscle adaptation
namespace: biological_process
def: "Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle]
synonym: "regulation of skeletal muscle plasticity" RELATED []
is_a: GO:0043502 ! regulation of muscle adaptation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0043501 ! skeletal muscle adaptation
relationship: regulates GO:0043501 ! skeletal muscle adaptation

[Term]
id: GO:0014734
name: skeletal muscle hypertrophy
namespace: biological_process
def: "The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle]
is_a: GO:0014897 ! striated muscle hypertrophy
is_a: GO:0043501 ! skeletal muscle adaptation
intersection_of: GO:0014896 ! muscle hypertrophy
intersection_of: occurs_in UBERON:0001134 ! skeletal muscle tissue

[Term]
id: GO:0014741
name: negative regulation of muscle hypertrophy
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy." [GOC:mtg_muscle]
is_a: GO:0014743 ! regulation of muscle hypertrophy
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014896 ! muscle hypertrophy
relationship: negatively_regulates GO:0014896 ! muscle hypertrophy

[Term]
id: GO:0014742
name: positive regulation of muscle hypertrophy
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle]
is_a: GO:0014743 ! regulation of muscle hypertrophy
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014896 ! muscle hypertrophy
relationship: positively_regulates GO:0014896 ! muscle hypertrophy

[Term]
id: GO:0014743
name: regulation of muscle hypertrophy
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle]
is_a: GO:0090257 ! regulation of muscle system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014896 ! muscle hypertrophy
relationship: regulates GO:0014896 ! muscle hypertrophy

[Term]
id: GO:0014744
name: positive regulation of muscle adaptation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of muscle adaptation." [GOC:mtg_muscle]
synonym: "positive regulation of muscle plasticity" RELATED []
is_a: GO:0043502 ! regulation of muscle adaptation
is_a: GO:0048584 ! positive regulation of response to stimulus
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0043500 ! muscle adaptation
relationship: positively_regulates GO:0043500 ! muscle adaptation

[Term]
id: GO:0014745
name: negative regulation of muscle adaptation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation." [GOC:mtg_muscle]
synonym: "negative regulation of muscle plasticity" RELATED []
is_a: GO:0043502 ! regulation of muscle adaptation
is_a: GO:0048585 ! negative regulation of response to stimulus
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0043500 ! muscle adaptation
relationship: negatively_regulates GO:0043500 ! muscle adaptation

[Term]
id: GO:0014805
name: smooth muscle adaptation
namespace: biological_process
def: "Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle]
synonym: "smooth muscle plasticity" RELATED []
is_a: GO:0043500 ! muscle adaptation
intersection_of: GO:0043500 ! muscle adaptation
intersection_of: occurs_in UBERON:0001135 ! smooth muscle tissue
relationship: occurs_in UBERON:0001135 ! smooth muscle tissue

[Term]
id: GO:0014807
name: regulation of somitogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of somitogenesis." [GOC:mtg_muscle]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001756 ! somitogenesis
relationship: regulates GO:0001756 ! somitogenesis

[Term]
id: GO:0014812
name: muscle cell migration
namespace: biological_process
def: "The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000187, GOC:mtg_muscle]
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000187 ! muscle cell
relationship: results_in_movement_of CL:0000187 ! muscle cell

[Term]
id: GO:0014819
name: regulation of skeletal muscle contraction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction." [GOC:ef, GOC:mtg_muscle]
is_a: GO:0006942 ! regulation of striated muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003009 ! skeletal muscle contraction
relationship: regulates GO:0003009 ! skeletal muscle contraction

[Term]
id: GO:0014821
name: phasic smooth muscle contraction
namespace: biological_process
def: "A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations." [GOC:mtg_muscle]
is_a: GO:0006939 ! smooth muscle contraction

[Term]
id: GO:0014827
name: intestine smooth muscle contraction
namespace: biological_process
def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine." [GOC:mtg_muscle, MA:0001539, MSH:D007422]
is_a: GO:0014821 ! phasic smooth muscle contraction
is_a: GO:0014831 ! gastro-intestinal system smooth muscle contraction

[Term]
id: GO:0014831
name: gastro-intestinal system smooth muscle contraction
namespace: biological_process
def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract)." [GOC:mtg_muscle, MA:0001523, MSH:D041981]
is_a: GO:0006939 ! smooth muscle contraction

[Term]
id: GO:0014832
name: urinary bladder smooth muscle contraction
namespace: biological_process
def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract." [GOC:mr, GOC:mtg_muscle, PMID:11768524, PMID:18276178, PMID:538956]
is_a: GO:0014848 ! urinary tract smooth muscle contraction
property_value: RO:0002161 NCBITaxon:8782

[Term]
id: GO:0014848
name: urinary tract smooth muscle contraction
namespace: biological_process
def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra." [GOC:ef, GOC:mtg_muscle, MA:0000325, MSH:D014551]
is_a: GO:0006939 ! smooth muscle contraction

[Term]
id: GO:0014849
name: ureter smooth muscle contraction
namespace: biological_process
def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_muscle, MA:0000378]
is_a: GO:0014821 ! phasic smooth muscle contraction
is_a: GO:0014848 ! urinary tract smooth muscle contraction

[Term]
id: GO:0014852
name: regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system." [GOC:ef, GOC:mtg_muscle]
is_a: GO:0014819 ! regulation of skeletal muscle contraction

[Term]
id: GO:0014855
name: striated muscle cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:ef, GOC:mtg_muscle]
is_a: GO:0033002 ! muscle cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000737 ! striated muscle cell
relationship: acts_on_population_of CL:0000737 ! striated muscle cell

[Term]
id: GO:0014856
name: skeletal muscle cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population." [CL:0000188, GOC:ef, GOC:mtg_muscle]
is_a: GO:0014855 ! striated muscle cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000188 ! cell of skeletal muscle
relationship: acts_on_population_of CL:0000188 ! cell of skeletal muscle

[Term]
id: GO:0014857
name: regulation of skeletal muscle cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014856 ! skeletal muscle cell proliferation
relationship: regulates GO:0014856 ! skeletal muscle cell proliferation

[Term]
id: GO:0014858
name: positive regulation of skeletal muscle cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014856 ! skeletal muscle cell proliferation
relationship: positively_regulates GO:0014856 ! skeletal muscle cell proliferation

[Term]
id: GO:0014859
name: negative regulation of skeletal muscle cell proliferation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014856 ! skeletal muscle cell proliferation
relationship: negatively_regulates GO:0014856 ! skeletal muscle cell proliferation

[Term]
id: GO:0014860
name: neurotransmitter secretion involved in regulation of skeletal muscle contraction
namespace: biological_process
def: "The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." [GOC:dph, GOC:mtg_muscle, GOC:tb]
synonym: "neurotransmitter secretion involved in control of skeletal muscle contraction" EXACT [GOC:dph, GOC:tb]
is_a: GO:0007269 ! neurotransmitter secretion
intersection_of: GO:0007269 ! neurotransmitter secretion
intersection_of: part_of GO:0014819 ! regulation of skeletal muscle contraction
relationship: part_of GO:0014852 ! regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction

[Term]
id: GO:0014861
name: regulation of skeletal muscle contraction via regulation of action potential
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_muscle]
synonym: "regulation of skeletal muscle contraction via membrane action potential" RELATED []
is_a: GO:0014819 ! regulation of skeletal muscle contraction
is_a: GO:0098900 ! regulation of action potential
intersection_of: GO:0050789 ! regulation of biological process
intersection_of: regulates GO:0100001 ! regulation of skeletal muscle contraction by action potential
relationship: regulates GO:0100001 ! regulation of skeletal muscle contraction by action potential

[Term]
id: GO:0014866
name: skeletal myofibril assembly
namespace: biological_process
def: "The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells." [GOC:ef, GOC:mtg_muscle]
is_a: GO:0030239 ! myofibril assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0098723 ! skeletal muscle myofibril
relationship: results_in_assembly_of GO:0098723 ! skeletal muscle myofibril

[Term]
id: GO:0014872
name: myoblast division
namespace: biological_process
def: "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle]
is_a: GO:0051301 ! cell division
intersection_of: GO:0051301 ! cell division
intersection_of: has_primary_input CL:0000056 ! myoblast
relationship: has_primary_input CL:0000056 ! myoblast

[Term]
id: GO:0014874
name: response to stimulus involved in regulation of muscle adaptation
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
synonym: "response to stimulus involved in regulation of muscle plasticity" RELATED []
is_a: GO:0050896 ! response to stimulus
intersection_of: GO:0050896 ! response to stimulus
intersection_of: part_of GO:0043502 ! regulation of muscle adaptation
relationship: part_of GO:0043502 ! regulation of muscle adaptation

[Term]
id: GO:0014878
name: response to electrical stimulus involved in regulation of muscle adaptation
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
synonym: "response to electrical stimulus involved in regulation of muscle plasticity" RELATED []
is_a: GO:0014874 ! response to stimulus involved in regulation of muscle adaptation
is_a: GO:0051602 ! response to electrical stimulus
intersection_of: GO:0051602 ! response to electrical stimulus
intersection_of: part_of GO:0043502 ! regulation of muscle adaptation

[Term]
id: GO:0014879
name: detection of electrical stimulus involved in regulation of muscle adaptation
namespace: biological_process
def: "The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle]
is_a: GO:0014878 ! response to electrical stimulus involved in regulation of muscle adaptation
is_a: GO:0050981 ! detection of electrical stimulus
intersection_of: GO:0050981 ! detection of electrical stimulus
intersection_of: part_of GO:0043502 ! regulation of muscle adaptation

[Term]
id: GO:0014887
name: cardiac muscle adaptation
namespace: biological_process
def: "The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:mtg_muscle]
synonym: "cardiac muscle plasticity" RELATED []
is_a: GO:0014888 ! striated muscle adaptation
intersection_of: GO:0043500 ! muscle adaptation
intersection_of: occurs_in UBERON:0001133 ! cardiac muscle tissue
relationship: occurs_in UBERON:0001133 ! cardiac muscle tissue

[Term]
id: GO:0014888
name: striated muscle adaptation
namespace: biological_process
def: "Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle]
synonym: "striated muscle plasticity" RELATED []
is_a: GO:0043500 ! muscle adaptation
intersection_of: GO:0043500 ! muscle adaptation
intersection_of: occurs_in UBERON:0002036 ! striated muscle tissue
relationship: occurs_in UBERON:0002036 ! striated muscle tissue

[Term]
id: GO:0014895
name: smooth muscle hypertrophy
namespace: biological_process
def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy." [GOC:mtg_muscle]
is_a: GO:0014805 ! smooth muscle adaptation
is_a: GO:0014896 ! muscle hypertrophy
intersection_of: GO:0014896 ! muscle hypertrophy
intersection_of: occurs_in UBERON:0001135 ! smooth muscle tissue

[Term]
id: GO:0014896
name: muscle hypertrophy
namespace: biological_process
def: "The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy." [GOC:mtg_muscle]
xref: Wikipedia:Muscle_hypertrophy
is_a: GO:0003012 ! muscle system process
relationship: occurs_in UBERON:0002385 ! muscle tissue

[Term]
id: GO:0014897
name: striated muscle hypertrophy
namespace: biological_process
def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle]
is_a: GO:0014896 ! muscle hypertrophy
intersection_of: GO:0014896 ! muscle hypertrophy
intersection_of: has_primary_input UBERON:0002036 ! striated muscle tissue
relationship: has_primary_input UBERON:0002036 ! striated muscle tissue

[Term]
id: GO:0014902
name: myotube differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle]
is_a: GO:0051146 ! striated muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002372 ! myotube
relationship: results_in_acquisition_of_features_of CL:0002372 ! myotube

[Term]
id: GO:0014904
name: myotube cell development
namespace: biological_process
def: "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle]
is_a: GO:0055002 ! striated muscle cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0002372 ! myotube
relationship: part_of GO:0014902 ! myotube differentiation
relationship: results_in_development_of CL:0002372 ! myotube

[Term]
id: GO:0014909
name: smooth muscle cell migration
namespace: biological_process
def: "The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000192, GOC:mtg_muscle]
is_a: GO:0014812 ! muscle cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000192 ! smooth muscle cell
relationship: results_in_movement_of CL:0000192 ! smooth muscle cell

[Term]
id: GO:0014910
name: regulation of smooth muscle cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle]
is_a: GO:0030334 ! regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014909 ! smooth muscle cell migration
relationship: regulates GO:0014909 ! smooth muscle cell migration

[Term]
id: GO:0014911
name: positive regulation of smooth muscle cell migration
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle]
is_a: GO:0014910 ! regulation of smooth muscle cell migration
is_a: GO:0030335 ! positive regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014909 ! smooth muscle cell migration
relationship: positively_regulates GO:0014909 ! smooth muscle cell migration

[Term]
id: GO:0014912
name: negative regulation of smooth muscle cell migration
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle]
is_a: GO:0014910 ! regulation of smooth muscle cell migration
is_a: GO:0030336 ! negative regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014909 ! smooth muscle cell migration
relationship: negatively_regulates GO:0014909 ! smooth muscle cell migration

[Term]
id: GO:0015031
name: protein transport
namespace: biological_process
alt_id: GO:0015831
def: "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
subset: goslim_chembl
subset: goslim_pir
subset: goslim_yeast
synonym: "enzyme transport" NARROW []
is_a: GO:0008104 ! protein localization
is_a: GO:0045184 ! establishment of protein localization
is_a: GO:0071702 ! organic substance transport
is_a: GO:0071705 ! nitrogen compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input PR:000000001 ! protein

[Term]
id: GO:0015075
name: monoatomic ion transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of an ion from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729]
synonym: "ion transmembrane transporter activity" BROAD []
synonym: "ion transporter activity" EXACT []
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion
relationship: has_primary_input CHEBI:24867 ! monoatomic ion
relationship: part_of GO:0034220 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! monoatomic ion transmembrane transport
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI

[Term]
id: GO:0015081
name: sodium ion transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0022816
def: "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." [GOC:ai, GOC:BHF, RHEA:34963]
synonym: "sodium transporter activity" EXACT []
xref: RHEA:34963
is_a: GO:0046873 ! metal ion transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:29101 ! sodium(1+)
relationship: has_participant CHEBI:29101 ! sodium(1+)
relationship: has_primary_input CHEBI:29101 ! sodium(1+)
relationship: part_of GO:0035725 ! sodium ion transmembrane transport
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI

[Term]
id: GO:0015101
name: organic cation transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
xref: Reactome:R-HSA-2161500 "abacavir [extracellular] => abacavir [cytosol]"
xref: Reactome:R-HSA-549129 "OCT1 transports organic cations into hepatic cells"
xref: Reactome:R-HSA-549279 "OCT2 mediates tubular uptake of organic cations in the kidney"
xref: Reactome:R-HSA-549304 "OCT3 mediates renal clearance of organic cations"
xref: Reactome:R-HSA-549322 "OCT1 transports organic cations out of hepatic cells"
xref: Reactome:R-HSA-561054 "OCT2 mediates tubular secretion of organic cations in the kidney"
xref: Reactome:R-HSA-561072 "OCT3 mediates renal uptake of organic cations"
xref: Reactome:R-HSA-9794270 "SLCO1A2 transports Cipro(1+) into the cytosol"
xref: Reactome:R-HSA-9794523 "SLC22A1 transports Cipro into renal cell"
xref: Reactome:R-HSA-9795207 "SLC22A1 transports Cipro into hepatic cell"
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:25697 ! organic cation
relationship: has_primary_input CHEBI:25697 ! organic cation
relationship: part_of GO:0015695 ! organic cation transport

[Term]
id: GO:0015103
name: inorganic anion transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:ai]
is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:24834 ! inorganic anion
relationship: has_primary_input CHEBI:24834 ! inorganic anion
relationship: part_of GO:0015698 ! inorganic anion transport

[Term]
id: GO:0015106
name: bicarbonate transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-." [GOC:ai]
xref: Reactome:R-HSA-2752067 "BESTs transport cytosolic HCO3- to extracellular region"
xref: RHEA:28695
is_a: GO:0008514 ! organic anion transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:17544 ! hydrogencarbonate
relationship: has_participant CHEBI:17544 ! hydrogencarbonate
relationship: has_primary_input CHEBI:17544 ! hydrogencarbonate
relationship: part_of GO:0015701 ! bicarbonate transport

[Term]
id: GO:0015114
name: phosphate ion transmembrane transporter activity
namespace: molecular_function
alt_id: GO:1901677
def: "Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other." [GOC:ai]
synonym: "phosphate transmembrane transporter activity" RELATED [GOC:vw]
xref: RHEA:32823
is_a: GO:0015103 ! inorganic anion transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:35780 ! phosphate ion
relationship: has_participant CHEBI:43474 ! hydrogenphosphate
relationship: has_primary_input CHEBI:35780 ! phosphate ion
relationship: part_of GO:0035435 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! phosphate ion transmembrane transport
created_by: pr
creation_date: 2012-11-22T15:43:10Z

[Term]
id: GO:0015116
name: sulfate transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other." [GOC:ai]
synonym: "sulfate permease activity" RELATED []
synonym: "sulphate transporter activity" EXACT []
xref: Reactome:R-HSA-3560789 "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol"
xref: Reactome:R-HSA-427555 "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol"
xref: Reactome:R-HSA-8875871 "SLC26A11 transports SO4(2-) from extracellular region to cytosol"
xref: RHEA:34983
is_a: GO:0015103 ! inorganic anion transmembrane transporter activity
is_a: GO:1901682 ! sulfur compound transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:16189 ! sulfate
relationship: has_participant CHEBI:16189 ! sulfate
relationship: has_primary_input CHEBI:16189 ! sulfate
relationship: part_of GO:1902358 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! sulfate transmembrane transport

[Term]
id: GO:0015123
name: acetate transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:ai]
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:30089 ! acetate
relationship: has_primary_input CHEBI:30089 ! acetate
relationship: part_of GO:0035433 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! acetate transmembrane transport

[Term]
id: GO:0015125
name: bile acid transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:ai]
xref: Reactome:R-HSA-194079 "SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol"
xref: Reactome:R-HSA-194083 "SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol"
xref: Reactome:R-HSA-194130 "Transport (influx) of bile salts and acids by OATP-A"
xref: Reactome:R-HSA-5661184 "Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)"
xref: Reactome:R-HSA-5661198 "Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)"
xref: Reactome:R-HSA-9733964 "SLC51A:SLC51B transports bile salts from cytosol to extracellular region"
is_a: GO:0005319 ! lipid transporter activity
is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity
is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:3098 ! bile acid
relationship: has_primary_input CHEBI:3098 ! bile acid
relationship: part_of GO:0015721 ! bile acid and bile salt transport

[Term]
id: GO:0015127
name: bilirubin transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile." [GOC:ai, ISBN:0198547684]
xref: Reactome:R-HSA-5679031 "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region"
xref: Reactome:R-HSA-5679041 "ABCC2 transports BMG,BDG from cytosol to extracellular region"
xref: Reactome:R-HSA-9661417 "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region"
is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:57977 ! bilirubin(2-)
relationship: has_primary_input CHEBI:57977 ! bilirubin(2-)
relationship: part_of GO:0015723 ! bilirubin transport

[Term]
id: GO:0015144
name: carbohydrate transmembrane transporter activity
namespace: molecular_function
alt_id: GO:1901476
def: "Enables the transfer of carbohydrate from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729]
synonym: "carbohydrate transporter activity" RELATED []
synonym: "sugar transporter" NARROW []
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:16646 ! carbohydrate
relationship: has_primary_input CHEBI:16646 ! carbohydrate
relationship: part_of GO:0034219 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! carbohydrate transmembrane transport

[Term]
id: GO:0015145
name: monosaccharide transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of a monosaccharide from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729]
is_a: GO:0051119 ! sugar transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:35381 ! monosaccharide
relationship: has_primary_input CHEBI:35381 ! monosaccharide
relationship: part_of GO:0015749 ! monosaccharide transmembrane transport

[Term]
id: GO:0015149
name: hexose transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
xref: Reactome:R-HSA-189242 "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region"
xref: Reactome:R-HSA-5638222 "Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region"
is_a: GO:0015145 ! monosaccharide transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:18133 ! hexose
relationship: has_primary_input CHEBI:18133 ! hexose
relationship: part_of GO:0008645 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! hexose transmembrane transport

[Term]
id: GO:0015159
name: polysaccharide transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
is_a: GO:0015144 ! carbohydrate transmembrane transporter activity
is_a: GO:0022884 ! macromolecule transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:18154 ! polysaccharide
relationship: has_primary_input CHEBI:18154 ! polysaccharide
relationship: part_of GO:0015774 ! polysaccharide transport

[Term]
id: GO:0015171
name: amino acid transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0015359
def: "Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group." [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
synonym: "amino acid permease activity" EXACT []
synonym: "amino acid transporter activity" BROAD []
synonym: "amino acid/choline transmembrane transporter activity" NARROW []
synonym: "general amino acid permease activity" RELATED []
synonym: "hydroxy/aromatic amino acid permease activity" RELATED []
xref: Reactome:R-HSA-210439 "glutamate uptake by astrocytes"
xref: Reactome:R-HSA-212642 "L-Glutamine transport into neurons"
xref: Reactome:R-HSA-351963 "SLC6A18 transports Gly from extracellular region to cytosol"
xref: Reactome:R-HSA-351987 "SLC6A6-mediated uptake of taurine and beta-alanine"
xref: Reactome:R-HSA-352029 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine"
xref: Reactome:R-HSA-352052 "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol"
xref: Reactome:R-HSA-352059 "SLC6A15-mediated amino acid uptake"
xref: Reactome:R-HSA-352103 "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids"
xref: Reactome:R-HSA-352107 "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids"
xref: Reactome:R-HSA-352108 "SLC38A2 (ATA2)-mediated uptake of neutral amino acids"
xref: Reactome:R-HSA-352119 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids"
xref: Reactome:R-HSA-352136 "SLC38A4 (ATA3)-mediated uptake of arginine and lysine"
xref: Reactome:R-HSA-352158 "SLC16A10-mediated uptake of aromatic amino acids"
xref: Reactome:R-HSA-352174 "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine"
xref: Reactome:R-HSA-352182 "SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine"
xref: Reactome:R-HSA-352191 "SLC7A8-mediated uptake of neutral amino acids"
xref: Reactome:R-HSA-352232 "SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol"
xref: Reactome:R-HSA-352347 "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine"
xref: Reactome:R-HSA-352354 "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine"
xref: Reactome:R-HSA-352364 "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine"
xref: Reactome:R-HSA-352371 "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine"
xref: Reactome:R-HSA-352379 "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane"
xref: Reactome:R-HSA-352385 "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane"
xref: Reactome:R-HSA-375405 "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol"
xref: Reactome:R-HSA-375417 "SLC36A1-mediated uptake of glycine, proline, and alanine"
xref: Reactome:R-HSA-375473 "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol"
xref: Reactome:R-HSA-375487 "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol"
xref: Reactome:R-HSA-375768 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids"
xref: Reactome:R-HSA-375770 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids"
xref: Reactome:R-HSA-375776 "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids"
xref: Reactome:R-HSA-375790 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids"
xref: Reactome:R-HSA-376200 "SLC7A10-mediated uptake of small neutral amino acids"
xref: Reactome:R-HSA-378513 "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate"
xref: Reactome:R-HSA-379415 "SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane"
xref: Reactome:R-HSA-379426 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine"
xref: Reactome:R-HSA-379432 "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu"
xref: Reactome:R-HSA-5653850 "Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol"
xref: Reactome:R-HSA-5655702 "Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu"
xref: Reactome:R-HSA-5659674 "Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol"
xref: Reactome:R-HSA-5659734 "Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol"
xref: Reactome:R-HSA-5659755 "Defective SLC6A18 does not transport Gly from extracellular region to cytosol"
xref: Reactome:R-HSA-5660694 "Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol"
xref: Reactome:R-HSA-5660890 "Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu"
xref: Reactome:R-HSA-5660910 "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane"
xref: Reactome:R-HSA-888592 "Loading of GABA into clathrin sculpted GABA transport vesicle lumen"
xref: Reactome:R-HSA-8952726 "SLC38A9 transports L-Arg from lysosomal lumen to cytosol"
is_a: GO:0005342 ! organic acid transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:33709 ! amino acid
relationship: has_primary_input CHEBI:33709 ! amino acid
relationship: part_of GO:0003333 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! amino acid transmembrane transport

[Term]
id: GO:0015205
name: nucleobase transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0015392
def: "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other." [ISBN:0198506732]
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:18282 ! nucleobase
relationship: has_primary_input CHEBI:18282 ! nucleobase
relationship: part_of GO:0015851 ! nucleobase transport

[Term]
id: GO:0015318
name: inorganic molecular entity transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon." [GOC:mtg_transport, ISBN:0815340729]
subset: gocheck_do_not_annotate
synonym: "inorganic solute uptake transmembrane transporter activity" EXACT []
synonym: "inorganic uptake permease activity" EXACT []
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:24835 ! inorganic molecular entity
relationship: has_primary_input CHEBI:24835 ! inorganic molecular entity
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14372" xsd:anyURI

[Term]
id: GO:0015629
name: actin cytoskeleton
namespace: cellular_component
def: "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." [GOC:jl, ISBN:0395825172, ISBN:0815316194]
is_a: GO:0005856 ! cytoskeleton

[Term]
id: GO:0015630
name: microtubule cytoskeleton
namespace: cellular_component
def: "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." [GOC:jl, ISBN:0395825172]
is_a: GO:0005856 ! cytoskeleton

[Term]
id: GO:0015669
name: gas transport
namespace: biological_process
def: "The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
subset: goslim_pir
is_a: GO:0006810 ! transport

[Term]
id: GO:0015671
name: oxygen transport
namespace: biological_process
def: "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
is_a: GO:0015669 ! gas transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:15379 ! dioxygen
relationship: has_primary_input CHEBI:15379 ! dioxygen

[Term]
id: GO:0015695
name: organic cation transport
namespace: biological_process
def: "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage." [GOC:ai]
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:25697 ! organic cation
relationship: has_primary_input CHEBI:25697 ! organic cation

[Term]
id: GO:0015698
name: inorganic anion transport
namespace: biological_process
def: "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:krc]
is_a: GO:0006810 ! transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:24834 ! inorganic anion
relationship: has_primary_input CHEBI:24834 ! inorganic anion

[Term]
id: GO:0015701
name: bicarbonate transport
namespace: biological_process
def: "The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc]
is_a: GO:0015711 ! organic anion transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:17544 ! hydrogencarbonate
relationship: has_primary_input CHEBI:17544 ! hydrogencarbonate

[Term]
id: GO:0015711
name: organic anion transport
namespace: biological_process
def: "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai, GOC:krc]
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:25696 ! organic anion
relationship: has_primary_input CHEBI:25696 ! organic anion

[Term]
id: GO:0015718
name: monocarboxylic acid transport
namespace: biological_process
def: "The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc]
is_a: GO:0046942 ! carboxylic acid transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:35757 ! monocarboxylic acid anion
relationship: has_primary_input CHEBI:35757 ! monocarboxylic acid anion

[Term]
id: GO:0015721
name: bile acid and bile salt transport
namespace: biological_process
def: "The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:krc, PMID:12663868, PMID:14699511]
synonym: "bile acid transport" NARROW []
synonym: "bile salt transport" NARROW []
is_a: GO:0006869 ! lipid transport
is_a: GO:0015718 ! monocarboxylic acid transport
is_a: GO:0015849 ! organic acid transport
is_a: GO:0015850 ! organic hydroxy compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:3098 ! bile acid
relationship: has_primary_input CHEBI:3098 ! bile acid

[Term]
id: GO:0015723
name: bilirubin transport
namespace: biological_process
def: "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc]
is_a: GO:0006835 ! dicarboxylic acid transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:57977 ! bilirubin(2-)
relationship: has_primary_input CHEBI:57977 ! bilirubin(2-)

[Term]
id: GO:0015749
name: monosaccharide transmembrane transport
namespace: biological_process
alt_id: GO:1905950
def: "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [GO_REF:0000069, GOC:TermGenie, GOC:vw]
synonym: "monosaccharide transport" RELATED []
is_a: GO:0034219 ! carbohydrate transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:35381 ! monosaccharide
intersection_of: results_in_transport_across GO:0016020 ! membrane
relationship: has_primary_input CHEBI:35381 ! monosaccharide
created_by: vw
creation_date: 2017-02-19T10:41:27Z

[Term]
id: GO:0015774
name: polysaccharide transport
namespace: biological_process
def: "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai]
is_a: GO:0008643 ! carbohydrate transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:18154 ! polysaccharide
relationship: has_primary_input CHEBI:18154 ! polysaccharide
relationship: part_of GO:0033037 ! polysaccharide localization

[Term]
id: GO:0015833
name: peptide transport
namespace: biological_process
def: "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
subset: goslim_pir
is_a: GO:0042886 ! amide transport
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:16670 ! peptide
relationship: has_primary_input CHEBI:16670 ! peptide

[Term]
id: GO:0015837
name: amine transport
namespace: biological_process
def: "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732]
subset: goslim_pir
synonym: "amine/polyamine transport" RELATED []
is_a: GO:0071702 ! organic substance transport
is_a: GO:0071705 ! nitrogen compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:32952 ! amine
relationship: has_primary_input CHEBI:32952 ! amine

[Term]
id: GO:0015844
name: monoamine transport
namespace: biological_process
alt_id: GO:0015873
def: "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
is_a: GO:0071702 ! organic substance transport
is_a: GO:0071705 ! nitrogen compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:63534 ! monoamine
relationship: has_primary_input CHEBI:63534 ! monoamine

[Term]
id: GO:0015849
name: organic acid transport
namespace: biological_process
def: "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732]
subset: goslim_pir
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:64709 ! organic acid
relationship: has_primary_input CHEBI:64709 ! organic acid

[Term]
id: GO:0015850
name: organic hydroxy compound transport
namespace: biological_process
def: "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom." [GOC:ai]
synonym: "organic alcohol transport" EXACT []
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound
relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound

[Term]
id: GO:0015851
name: nucleobase transport
namespace: biological_process
def: "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732]
synonym: "nucleobase transmembrane transport" EXACT [GOC:mah]
is_a: GO:0071702 ! organic substance transport
is_a: GO:0071705 ! nitrogen compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:18282 ! nucleobase
relationship: has_primary_input CHEBI:18282 ! nucleobase

[Term]
id: GO:0015869
name: protein-DNA complex transport
namespace: biological_process
def: "The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "DNA-protein complex transport" EXACT [GOC:mah]
is_a: GO:0006886 ! intracellular protein transport
is_a: GO:0015931 ! nucleobase-containing compound transport
is_a: GO:0031503 ! protein-containing complex localization
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input GO:0032993 ! protein-DNA complex
relationship: has_primary_input GO:0032993 ! protein-DNA complex

[Term]
id: GO:0015870
name: acetylcholine transport
namespace: biological_process
def: "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai]
is_a: GO:0015695 ! organic cation transport
is_a: GO:0071705 ! nitrogen compound transport
is_a: GO:1901374 ! acetate ester transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:15355 ! acetylcholine
relationship: has_primary_input CHEBI:15355 ! acetylcholine

[Term]
id: GO:0015874
name: norepinephrine transport
namespace: biological_process
def: "The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai, ISBN:0198506732]
synonym: "levarterenol transport" EXACT []
synonym: "noradrenaline transport" EXACT []
is_a: GO:0015695 ! organic cation transport
is_a: GO:0051937 ! catecholamine transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+)
relationship: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+)

[Term]
id: GO:0015931
name: nucleobase-containing compound transport
namespace: biological_process
def: "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
subset: goslim_pir
subset: goslim_yeast
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb]
is_a: GO:0071702 ! organic substance transport
is_a: GO:0071705 ! nitrogen compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity
relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity

[Term]
id: GO:0015932
name: nucleobase-containing compound transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other." [GOC:ai]
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity" RELATED [GOC:dph, GOC:tb]
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity
relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity
relationship: part_of GO:0015931 ! nucleobase-containing compound transport

[Term]
id: GO:0015980
name: energy derivation by oxidation of organic compounds
namespace: biological_process
def: "The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released." [GOC:mah]
synonym: "chemoorganotrophy" EXACT []
is_a: GO:0006091 ! generation of precursor metabolites and energy

[Term]
id: GO:0016020
name: membrane
namespace: cellular_component
alt_id: GO:0016021
alt_id: GO:0098589
alt_id: GO:0098805
def: "A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it." [GOC:dos, GOC:mah, ISBN:0815316194]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_plant
subset: goslim_yeast
synonym: "integral component of membrane" NARROW []
synonym: "integral to membrane" NARROW []
synonym: "membrane region" NARROW []
synonym: "region of membrane" NARROW []
synonym: "transmembrane" RELATED [GOC:mah]
synonym: "whole membrane" NARROW []
xref: Wikipedia:Biological_membrane
xref: Wikipedia:Transmembrane_protein
is_a: GO:0110165 ! cellular anatomical entity
disjoint_from: GO:0031012 ! extracellular matrix
creation_date: 2014-03-06T11:37:54Z

[Term]
id: GO:0016042
name: lipid catabolic process
namespace: biological_process
alt_id: GO:0006724
alt_id: GO:0044240
def: "The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators]
synonym: "lipid breakdown" EXACT []
synonym: "lipid catabolism" EXACT []
synonym: "lipid degradation" EXACT []
synonym: "lipolysis" EXACT []
synonym: "multicellular organism lipid catabolic process" NARROW []
synonym: "multicellular organismal lipid catabolic process" NARROW []
xref: Wikipedia:Lipid_catabolism
is_a: GO:0006629 ! lipid metabolic process
is_a: GO:1901575 ! organic substance catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:18059 ! lipid
relationship: has_primary_input CHEBI:18059 ! lipid

[Term]
id: GO:0016043
name: cellular component organization
namespace: biological_process
alt_id: GO:0044235
alt_id: GO:0071842
def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:ai, GOC:jl, GOC:mah]
subset: goslim_agr
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
synonym: "cell organisation" EXACT []
synonym: "cell organization and biogenesis" RELATED [GOC:mah]
synonym: "cellular component organisation at cellular level" EXACT [GOC:mah]
synonym: "cellular component organisation in other organism" EXACT [GOC:mah]
synonym: "cellular component organization at cellular level" EXACT []
synonym: "cellular component organization in other organism" EXACT []
is_a: GO:0071840 ! cellular component organization or biogenesis
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_organization_of GO:0005575 ! cellular_component
relationship: results_in_organization_of GO:0005575 ! cellular_component

[Term]
id: GO:0016049
name: cell growth
namespace: biological_process
alt_id: GO:0048591
def: "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GOC:ai]
subset: gocheck_do_not_annotate
subset: goslim_drosophila
subset: goslim_pir
subset: goslim_plant
synonym: "cell expansion" RELATED []
synonym: "cellular growth" EXACT []
synonym: "growth of cell" EXACT []
synonym: "metabolic process resulting in cell growth" RELATED []
synonym: "metabolism resulting in cell growth" RELATED []
synonym: "non-developmental cell growth" RELATED [GOC:mah]
synonym: "non-developmental growth of a unicellular organism" RELATED [GOC:mah]
is_a: GO:0009987 ! cellular process
is_a: GO:0040007 ! growth
intersection_of: GO:0040007 ! growth
intersection_of: results_in_growth_of CL:0000000 ! cell
relationship: results_in_growth_of CL:0000000 ! cell

[Term]
id: GO:0016050
name: vesicle organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle." [GOC:mah]
subset: goslim_pir
subset: goslim_yeast
synonym: "vesicle organisation" EXACT []
synonym: "vesicle organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0006996 ! organelle organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0031982 ! vesicle
relationship: results_in_organization_of GO:0031982 ! vesicle

[Term]
id: GO:0016051
name: carbohydrate biosynthetic process
namespace: biological_process
alt_id: GO:0006093
def: "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732]
synonym: "anabolic carbohydrate metabolic process" EXACT []
synonym: "anabolic carbohydrate metabolism" EXACT []
synonym: "carbohydrate anabolism" EXACT []
synonym: "carbohydrate biosynthesis" EXACT []
synonym: "carbohydrate formation" EXACT []
synonym: "carbohydrate synthesis" EXACT []
is_a: GO:0005975 ! carbohydrate metabolic process
is_a: GO:1901576 ! organic substance biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:16646 ! carbohydrate
relationship: has_primary_output CHEBI:16646 ! carbohydrate

[Term]
id: GO:0016052
name: carbohydrate catabolic process
namespace: biological_process
alt_id: GO:0006095
alt_id: GO:0044276
alt_id: GO:0044724
def: "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732]
synonym: "carbohydrate breakdown" EXACT []
synonym: "carbohydrate catabolism" EXACT []
synonym: "carbohydrate degradation" EXACT []
synonym: "catabolic carbohydrate metabolic process" EXACT []
synonym: "catabolic carbohydrate metabolism" EXACT []
synonym: "multicellular organismal carbohydrate catabolic process" NARROW []
synonym: "single-organism carbohydrate catabolic process" RELATED []
is_a: GO:0005975 ! carbohydrate metabolic process
is_a: GO:1901575 ! organic substance catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:16646 ! carbohydrate
relationship: has_primary_input CHEBI:16646 ! carbohydrate
created_by: jl
creation_date: 2012-10-23T16:34:39Z

[Term]
id: GO:0016053
name: organic acid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732]
synonym: "organic acid anabolism" EXACT []
synonym: "organic acid biosynthesis" EXACT []
synonym: "organic acid formation" EXACT []
synonym: "organic acid synthesis" EXACT []
is_a: GO:0006082 ! organic acid metabolic process
is_a: GO:0044249 ! cellular biosynthetic process
is_a: GO:0044283 ! small molecule biosynthetic process
is_a: GO:1901576 ! organic substance biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:64709 ! organic acid
relationship: has_primary_output CHEBI:64709 ! organic acid

[Term]
id: GO:0016054
name: organic acid catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732]
synonym: "organic acid breakdown" EXACT []
synonym: "organic acid catabolism" EXACT []
synonym: "organic acid degradation" EXACT []
is_a: GO:0006082 ! organic acid metabolic process
is_a: GO:0044248 ! cellular catabolic process
is_a: GO:0044282 ! small molecule catabolic process
is_a: GO:1901575 ! organic substance catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:64709 ! organic acid
relationship: has_primary_input CHEBI:64709 ! organic acid

[Term]
id: GO:0016057
name: regulation of membrane potential in photoreceptor cell
namespace: biological_process
def: "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon." [GOC:dph, GOC:hb, GOC:tb]
synonym: "changes in polarization state of photoreceptor cell membrane" EXACT [GOC:dph, GOC:tb]
is_a: GO:0042391 ! regulation of membrane potential
intersection_of: GO:0042391 ! regulation of membrane potential
intersection_of: occurs_in CL:0000210 ! photoreceptor cell
relationship: occurs_in CL:0000210 ! photoreceptor cell

[Term]
id: GO:0016070
name: RNA metabolic process
namespace: biological_process
def: "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732]
subset: goslim_agr
subset: goslim_candida
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_prokaryote
synonym: "RNA metabolism" EXACT []
is_a: GO:0090304 ! nucleic acid metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:33697 ! ribonucleic acid
relationship: has_primary_input_or_output CHEBI:33697 ! ribonucleic acid

[Term]
id: GO:0016192
name: vesicle-mediated transport
namespace: biological_process
alt_id: GO:0006899
def: "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." [GOC:ai, GOC:mah, ISBN:08789310662000]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pir
subset: goslim_pombe
synonym: "nonselective vesicle transport" NARROW []
synonym: "protein sorting along secretory pathway" RELATED []
synonym: "vesicle trafficking" RELATED []
synonym: "vesicle transport" EXACT []
synonym: "vesicular transport" EXACT [GOC:mah]
is_a: GO:0006810 ! transport
is_a: GO:0009987 ! cellular process
intersection_of: GO:0006810 ! transport
intersection_of: process_has_causal_agent GO:0031982 ! vesicle
relationship: process_has_causal_agent GO:0031982 ! vesicle
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25421" xsd:anyURI

[Term]
id: GO:0016202
name: regulation of striated muscle tissue development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of striated muscle development." [GOC:go_curators]
is_a: GO:0048634 ! regulation of muscle organ development
is_a: GO:1901861 ! regulation of muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014706 ! striated muscle tissue development
relationship: regulates GO:0014706 ! striated muscle tissue development

[Term]
id: GO:0016301
name: kinase activity
namespace: molecular_function
def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732]
comment: Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term.
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_metagenomics
subset: goslim_plant
subset: goslim_yeast
synonym: "phosphokinase activity" EXACT []
xref: Reactome:R-HSA-6788855 "FN3KRP phosphorylates PsiAm, RibAm"
xref: Reactome:R-HSA-6788867 "FN3K phosphorylates ketosamines"
is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups

[Term]
id: GO:0016310
name: phosphorylation
namespace: biological_process
def: "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732]
subset: goslim_chembl
subset: goslim_metagenomics
xref: Wikipedia:Phosphorylation
is_a: GO:0006796 ! phosphate-containing compound metabolic process

[Term]
id: GO:0016321
name: female meiosis chromosome segregation
namespace: biological_process
def: "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." [GOC:ai]
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0045132 ! meiotic chromosome segregation
intersection_of: GO:0098813 ! nuclear chromosome segregation
intersection_of: part_of GO:0007143 ! female meiotic nuclear division
relationship: part_of GO:0007143 ! female meiotic nuclear division

[Term]
id: GO:0016325
name: oocyte microtubule cytoskeleton organization
namespace: biological_process
alt_id: GO:0048130
def: "Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11231123]
synonym: "oocyte microtubule cytoskeleton organisation" EXACT []
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0030951 ! establishment or maintenance of microtubule cytoskeleton polarity
intersection_of: GO:0016043 ! cellular component organization
intersection_of: occurs_in CL:0000023 ! oocyte
intersection_of: results_in_organization_of GO:0015630 ! microtubule cytoskeleton
relationship: occurs_in CL:0000023 ! oocyte
relationship: part_of GO:0007308 ! oocyte construction

[Term]
id: GO:0016331
name: morphogenesis of embryonic epithelium
namespace: biological_process
def: "The process in which the anatomical structures of embryonic epithelia are generated and organized." [GOC:jl]
is_a: GO:0002009 ! morphogenesis of an epithelium
is_a: GO:0048598 ! embryonic morphogenesis

[Term]
id: GO:0016477
name: cell migration
namespace: biological_process
def: "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration]
xref: Wikipedia:Cell_migration
is_a: GO:0048870 ! cell motility
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24787" xsd:anyURI
property_value: RO:0002161 NCBITaxon:4890

[Term]
id: GO:0016525
name: negative regulation of angiogenesis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis." [GOC:go_curators]
synonym: "down regulation of angiogenesis" EXACT []
synonym: "down-regulation of angiogenesis" EXACT []
synonym: "downregulation of angiogenesis" EXACT []
synonym: "inhibition of angiogenesis" NARROW []
is_a: GO:0045765 ! regulation of angiogenesis
is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001525 ! angiogenesis
relationship: negatively_regulates GO:0001525 ! angiogenesis

[Term]
id: GO:0016528
name: sarcoplasm
namespace: cellular_component
def: "The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum." [ISBN:0198547684]
xref: Wikipedia:Sarcoplasm
is_a: GO:0005737 ! cytoplasm
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: GO:0005737 ! cytoplasm
intersection_of: part_of CL:0000187 ! muscle cell
relationship: part_of CL:0000187 ! muscle cell
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0016740
name: transferase activity
namespace: molecular_function
def: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_prokaryote
subset: goslim_yeast
xref: EC:2.-.-.-
xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2"
xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1"
xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK"
xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248"
is_a: GO:0003824 ! catalytic activity

[Term]
id: GO:0016772
name: transferase activity, transferring phosphorus-containing groups
namespace: molecular_function
def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732]
comment: Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides.
subset: goslim_chembl
xref: EC:2.7.-.-
is_a: GO:0016740 ! transferase activity

[Term]
id: GO:0016787
name: hydrolase activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc." [ISBN:0198506732]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
subset: goslim_prokaryote
subset: goslim_yeast
xref: EC:3.-.-.-
xref: Reactome:R-HSA-1236938 "Partial proteolysis of antigen in phagolysosomes"
xref: Reactome:R-HSA-2029475 "Production of AA by iPLA2 upon FCGR activation"
xref: Reactome:R-HSA-5694583 "ABHD4 hydrolyses NAPE"
xref: Reactome:R-HSA-5695964 "ABHD14B hydrolyses PNPB"
xref: Reactome:R-HSA-6786190 "CMBL hydrolyses OM to OLMS"
xref: Reactome:R-HSA-6788295 "HDHD1:Mg2+ dephosphorylates PURIDP"
xref: Reactome:R-HSA-8938314 "ENPPs hydrolyse CoA-SH to PPANT, PAP"
xref: Reactome:R-HSA-8952137 "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate"
is_a: GO:0003824 ! catalytic activity

[Term]
id: GO:0016788
name: hydrolase activity, acting on ester bonds
namespace: molecular_function
def: "Catalysis of the hydrolysis of any ester bond." [GOC:jl]
subset: goslim_chembl
synonym: "esterase activity" EXACT []
xref: EC:3.1.-.-
xref: Reactome:R-HSA-162729 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid"
xref: Reactome:R-HSA-9023617 "Butyrylcholinesterase hydrolyzes acyl Ghrelin"
xref: Reactome:R-HSA-9023619 "Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin"
xref: Reactome:R-HSA-9749609 "BCHE hydrolyzes ASA-"
is_a: GO:0016787 ! hydrolase activity

[Term]
id: GO:0017085
name: response to insecticide
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects." [GOC:curators]
synonym: "insecticide resistance" RELATED []
synonym: "insecticide susceptibility/resistance" RELATED []
is_a: GO:0009636 ! response to toxic substance

[Term]
id: GO:0017126
name: nucleologenesis
namespace: biological_process
def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells." [GOC:jl, ISBN:0198506732]
synonym: "nucleolus assembly" NARROW [GOC:mah]
synonym: "nucleolus biogenesis" EXACT []
is_a: GO:0007000 ! nucleolus organization
is_a: GO:0044085 ! cellular component biogenesis
intersection_of: GO:0044085 ! cellular component biogenesis
intersection_of: has_primary_output GO:0005730 ! nucleolus
relationship: has_primary_output GO:0005730 ! nucleolus

[Term]
id: GO:0017145
name: stem cell division
namespace: biological_process
def: "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." [GOC:jid, ISBN:0582227089]
synonym: "stem cell renewal" EXACT []
is_a: GO:0051301 ! cell division
intersection_of: GO:0051301 ! cell division
intersection_of: has_primary_input CL:0000034 ! stem cell
relationship: has_primary_input CL:0000034 ! stem cell
property_value: RO:0002161 NCBITaxon_Union:0000023

[Term]
id: GO:0017148
name: negative regulation of translation
namespace: biological_process
alt_id: GO:0016478
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete]
synonym: "down regulation of protein biosynthetic process" EXACT []
synonym: "down-regulation of protein biosynthetic process" EXACT []
synonym: "downregulation of protein biosynthetic process" EXACT []
synonym: "inhibition of protein biosynthetic process" NARROW []
synonym: "negative regulation of protein anabolism" EXACT []
synonym: "negative regulation of protein biosynthesis" EXACT []
synonym: "negative regulation of protein biosynthetic process" EXACT []
synonym: "negative regulation of protein formation" EXACT []
synonym: "negative regulation of protein synthesis" EXACT []
synonym: "protein biosynthesis inhibitor activity" RELATED []
synonym: "protein biosynthetic process inhibitor activity" RELATED []
is_a: GO:0006417 ! regulation of translation
is_a: GO:0010629 ! negative regulation of gene expression
is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0051248 ! negative regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006412 ! translation
relationship: negatively_regulates GO:0006412 ! translation

[Term]
id: GO:0017157
name: regulation of exocytosis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of exocytosis." [GOC:go_curators]
is_a: GO:0060627 ! regulation of vesicle-mediated transport
is_a: GO:1903530 ! regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006887 ! exocytosis
relationship: regulates GO:0006887 ! exocytosis

[Term]
id: GO:0018130
name: heterocycle biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198547684]
synonym: "heterocycle anabolism" EXACT []
synonym: "heterocycle biosynthesis" EXACT []
synonym: "heterocycle formation" EXACT []
synonym: "heterocycle synthesis" EXACT []
is_a: GO:0044249 ! cellular biosynthetic process
is_a: GO:0046483 ! heterocycle metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:5686 ! heterocyclic compound
relationship: has_primary_output CHEBI:5686 ! heterocyclic compound

[Term]
id: GO:0018958
name: phenol-containing compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732]
comment: Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds.
synonym: "carbolic acid metabolic process" EXACT []
synonym: "carbolic acid metabolism" EXACT []
synonym: "hydroxybenzene metabolic process" EXACT []
synonym: "hydroxybenzene metabolism" EXACT []
synonym: "phenol-containing compound metabolism" EXACT []
xref: UM-BBD_pathwayID:phe
is_a: GO:0006725 ! cellular aromatic compound metabolic process
is_a: GO:1901360 ! organic cyclic compound metabolic process
is_a: GO:1901615 ! organic hydroxy compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:33853 ! phenols
relationship: has_primary_input_or_output CHEBI:33853 ! phenols

[Term]
id: GO:0019098
name: reproductive behavior
namespace: biological_process
alt_id: GO:0033057
alt_id: GO:0044704
alt_id: GO:0044705
def: "The specific behavior of an organism that is associated with reproduction." [GOC:jl, GOC:pr]
synonym: "multi-organism reproductive behavior" NARROW []
synonym: "multicellular organism reproductive behavior" NARROW []
synonym: "reproductive behavior in a multicellular organism" EXACT []
synonym: "reproductive behaviour" EXACT []
synonym: "single-organism reproductive behavior" RELATED []
is_a: GO:0007610 ! behavior
is_a: GO:0022414 ! reproductive process
intersection_of: GO:0007610 ! behavior
intersection_of: part_of GO:0032504 ! multicellular organism reproduction
relationship: part_of GO:0032504 ! multicellular organism reproduction
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23491" xsd:anyURI
created_by: jl
creation_date: 2012-09-19T16:01:37Z

[Term]
id: GO:0019216
name: regulation of lipid metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators]
synonym: "regulation of lipid metabolism" EXACT []
is_a: GO:0080090 ! regulation of primary metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006629 ! lipid metabolic process
relationship: regulates GO:0006629 ! lipid metabolic process

[Term]
id: GO:0019218
name: regulation of steroid metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators]
synonym: "regulation of steroid metabolism" EXACT []
is_a: GO:0019216 ! regulation of lipid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008202 ! steroid metabolic process
relationship: regulates GO:0008202 ! steroid metabolic process

[Term]
id: GO:0019219
name: regulation of nucleobase-containing compound metabolic process
namespace: biological_process
def: "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators]
synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb]
synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT []
is_a: GO:0031323 ! regulation of cellular metabolic process
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
is_a: GO:0080090 ! regulation of primary metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006139 ! nucleobase-containing compound metabolic process
relationship: regulates GO:0006139 ! nucleobase-containing compound metabolic process

[Term]
id: GO:0019220
name: regulation of phosphate metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators]
synonym: "regulation of phosphate metabolism" EXACT []
is_a: GO:0051174 ! regulation of phosphorus metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006796 ! phosphate-containing compound metabolic process
relationship: regulates GO:0006796 ! phosphate-containing compound metabolic process

[Term]
id: GO:0019222
name: regulation of metabolic process
namespace: biological_process
alt_id: GO:0044246
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators]
subset: goslim_metagenomics
synonym: "regulation of metabolism" EXACT []
synonym: "regulation of multicellular organismal metabolic process" NARROW []
synonym: "regulation of organismal metabolic process" NARROW [GOC:tb]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008152 ! metabolic process
relationship: regulates GO:0008152 ! metabolic process

[Term]
id: GO:0019226
name: transmission of nerve impulse
namespace: biological_process
def: "The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission." [GOC:curators, ISBN:0815316194]
synonym: "conduction of nerve impulse" EXACT [GOC:dph]
synonym: "signal transmission along a neuron" EXACT []
is_a: GO:0050877 ! nervous system process
relationship: has_part GO:0001508 ! action potential
relationship: has_part GO:0007268 ! chemical synaptic transmission
relationship: part_of GO:0007154 ! cell communication

[Term]
id: GO:0019228
name: neuronal action potential
namespace: biological_process
def: "An action potential that occurs in a neuron." [GOC:dph, GOC:isa_complete, GOC:tb]
synonym: "generation of action potential" RELATED [GOC:dph, GOC:tb]
is_a: GO:0001508 ! action potential
intersection_of: GO:0001508 ! action potential
intersection_of: occurs_in CL:0000540 ! neuron
relationship: occurs_in CL:0000540 ! neuron
relationship: part_of GO:0019226 ! transmission of nerve impulse

[Term]
id: GO:0019233
name: sensory perception of pain
namespace: biological_process
def: "The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process." [GOC:curators]
synonym: "nociception" RELATED []
synonym: "perception of physiological pain" NARROW []
xref: Wikipedia:Nociception
is_a: GO:0007600 ! sensory perception

[Term]
id: GO:0019318
name: hexose metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732]
synonym: "hexose metabolism" EXACT []
is_a: GO:0005996 ! monosaccharide metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:18133 ! hexose
relationship: has_primary_input_or_output CHEBI:18133 ! hexose

[Term]
id: GO:0019319
name: hexose biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732]
synonym: "hexose anabolism" EXACT []
synonym: "hexose biosynthesis" EXACT []
synonym: "hexose formation" EXACT []
synonym: "hexose synthesis" EXACT []
is_a: GO:0019318 ! hexose metabolic process
is_a: GO:0046364 ! monosaccharide biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:18133 ! hexose
relationship: has_primary_output CHEBI:18133 ! hexose

[Term]
id: GO:0019320
name: hexose catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732]
synonym: "hexose breakdown" EXACT []
synonym: "hexose catabolism" EXACT []
synonym: "hexose degradation" EXACT []
is_a: GO:0019318 ! hexose metabolic process
is_a: GO:0046365 ! monosaccharide catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:18133 ! hexose
relationship: has_primary_input CHEBI:18133 ! hexose

[Term]
id: GO:0019336
name: phenol-containing compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732]
synonym: "phenol-containing compound breakdown" EXACT []
synonym: "phenol-containing compound catabolism" EXACT []
synonym: "phenol-containing compound degradation" EXACT []
xref: MetaCyc:PHENOLDEG-PWY
is_a: GO:0018958 ! phenol-containing compound metabolic process
is_a: GO:0019439 ! aromatic compound catabolic process
is_a: GO:1901361 ! organic cyclic compound catabolic process
is_a: GO:1901616 ! organic hydroxy compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:33853 ! phenols
relationship: has_primary_input CHEBI:33853 ! phenols

[Term]
id: GO:0019413
name: acetate biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid." [GOC:go_curators]
synonym: "acetate anabolism" EXACT []
synonym: "acetate biosynthesis" EXACT []
synonym: "acetate formation" EXACT []
synonym: "acetate synthesis" EXACT []
is_a: GO:0006083 ! acetate metabolic process
is_a: GO:0072330 ! monocarboxylic acid biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:30089 ! acetate
relationship: has_primary_output CHEBI:30089 ! acetate

[Term]
id: GO:0019438
name: aromatic compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai]
synonym: "aromatic compound anabolism" EXACT []
synonym: "aromatic compound biosynthesis" EXACT []
synonym: "aromatic compound formation" EXACT []
synonym: "aromatic compound synthesis" EXACT []
synonym: "aromatic hydrocarbon biosynthesis" NARROW []
synonym: "aromatic hydrocarbon biosynthetic process" NARROW []
is_a: GO:0006725 ! cellular aromatic compound metabolic process
is_a: GO:0044249 ! cellular biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:33655 ! aromatic compound
relationship: has_primary_output CHEBI:33655 ! aromatic compound

[Term]
id: GO:0019439
name: aromatic compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai]
synonym: "aromatic compound breakdown" EXACT []
synonym: "aromatic compound catabolism" EXACT []
synonym: "aromatic compound degradation" EXACT []
synonym: "aromatic hydrocarbon catabolic process" NARROW []
synonym: "aromatic hydrocarbon catabolism" NARROW []
is_a: GO:0006725 ! cellular aromatic compound metabolic process
is_a: GO:0044248 ! cellular catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:33655 ! aromatic compound
relationship: has_primary_input CHEBI:33655 ! aromatic compound

[Term]
id: GO:0019538
name: protein metabolic process
namespace: biological_process
alt_id: GO:0006411
alt_id: GO:0044267
alt_id: GO:0044268
def: "The chemical reactions and pathways involving a protein. Includes protein modification." [GOC:ma]
subset: goslim_agr
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_pir
subset: goslim_plant
synonym: "cellular protein metabolic process" EXACT []
synonym: "cellular protein metabolism" EXACT []
synonym: "multicellular organismal protein metabolic process" NARROW []
synonym: "protein metabolic process and modification" EXACT []
synonym: "protein metabolism" EXACT []
synonym: "protein metabolism and modification" EXACT []
xref: Wikipedia:Protein_metabolism
is_a: GO:0044238 ! primary metabolic process
is_a: GO:1901564 ! organonitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output PR:000000001 ! protein
relationship: has_primary_input_or_output PR:000000001 ! protein
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI

[Term]
id: GO:0019614
name: catechol-containing compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators]
synonym: "catechol breakdown" RELATED []
synonym: "catechol catabolic process" RELATED []
synonym: "catechol catabolism" RELATED []
synonym: "catechol degradation" RELATED []
is_a: GO:0009712 ! catechol-containing compound metabolic process
is_a: GO:0019336 ! phenol-containing compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:33566 ! catechols
relationship: has_primary_input CHEBI:33566 ! catechols

[Term]
id: GO:0019725
name: cellular homeostasis
namespace: biological_process
def: "Any process involved in the maintenance of an internal steady state at the level of the cell." [GOC:isa_complete, GOC:jl, ISBN:0395825172]
subset: goslim_candida
subset: goslim_plant
is_a: GO:0042592 ! homeostatic process
intersection_of: GO:0042592 ! homeostatic process
intersection_of: occurs_in CL:0000000 ! cell
disjoint_from: GO:0048872 ! homeostasis of number of cells
relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms
relationship: occurs_in CL:0000000 ! cell
relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms

[Term]
id: GO:0019748
name: secondary metabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." [GOC:go_curators]
subset: goslim_chembl
subset: goslim_pir
subset: goslim_plant
subset: goslim_pombe
synonym: "secondary metabolism" EXACT []
synonym: "secondary metabolite metabolic process" EXACT []
synonym: "secondary metabolite metabolism" EXACT []
xref: Wikipedia:Secondary_metabolism
is_a: GO:0008152 ! metabolic process

[Term]
id: GO:0019752
name: carboxylic acid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732]
synonym: "carboxylic acid metabolism" EXACT []
is_a: GO:0043436 ! oxoacid metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:29067 ! carboxylic acid anion
relationship: has_primary_input_or_output CHEBI:29067 ! carboxylic acid anion

[Term]
id: GO:0019755
name: one-carbon compound transport
namespace: biological_process
def: "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "one carbon compound transport" EXACT []
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:64708 ! one-carbon compound
relationship: has_primary_input CHEBI:64708 ! one-carbon compound

[Term]
id: GO:0019827
name: stem cell population maintenance
namespace: biological_process
def: "The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types." [GOC:mah, ISBN:0878932437]
synonym: "maintenance of pluripotency" RELATED [GOC:vk]
is_a: GO:0032501 ! multicellular organismal process
is_a: GO:0098727 ! maintenance of cell number
intersection_of: GO:0098727 ! maintenance of cell number
intersection_of: acts_on_population_of CL:0000034 ! stem cell
relationship: acts_on_population_of CL:0000034 ! stem cell

[Term]
id: GO:0019867
name: outer membrane
namespace: cellular_component
def: "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites." [GOC:go_curators]
subset: goslim_metagenomics
is_a: GO:0016020 ! membrane

[Term]
id: GO:0019882
name: antigen processing and presentation
namespace: biological_process
alt_id: GO:0030333
def: "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678]
synonym: "antigen presentation" EXACT []
synonym: "antigen processing" EXACT []
xref: Wikipedia:Antigen_presentation
is_a: GO:0002376 ! immune system process

[Term]
id: GO:0019953
name: sexual reproduction
namespace: biological_process
def: "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)." [Wikipedia:Sexual_reproduction]
comment: Note that gametes may come from two organisms or from a single organism in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. Note also that sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times.
xref: Wikipedia:Sexual_reproduction
is_a: GO:0000003 ! reproduction
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22929" xsd:anyURI

[Term]
id: GO:0021501
name: prechordal plate formation
namespace: biological_process
def: "The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003063 ! prechordal plate
relationship: part_of GO:0007399 ! nervous system development
relationship: results_in_formation_of_anatomical_entity UBERON:0003063 ! prechordal plate

[Term]
id: GO:0021510
name: spinal cord development
namespace: biological_process
def: "The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002240 ! spinal cord
relationship: part_of GO:0007417 ! central nervous system development
relationship: results_in_development_of UBERON:0002240 ! spinal cord

[Term]
id: GO:0021514
name: ventral spinal cord interneuron differentiation
namespace: biological_process
def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]
is_a: GO:0021515 ! cell differentiation in spinal cord
is_a: GO:0021953 ! central nervous system neuron differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: occurs_in UBERON:0002240 ! spinal cord
intersection_of: results_in_acquisition_of_features_of CL:0000099 ! interneuron
relationship: part_of GO:0021517 ! ventral spinal cord development
relationship: results_in_acquisition_of_features_of CL:0000099 ! interneuron

[Term]
id: GO:0021515
name: cell differentiation in spinal cord
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: occurs_in UBERON:0002240 ! spinal cord
relationship: occurs_in UBERON:0002240 ! spinal cord
relationship: part_of GO:0021510 ! spinal cord development

[Term]
id: GO:0021517
name: ventral spinal cord development
namespace: biological_process
def: "The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002257 ! ventral horn of spinal cord
relationship: part_of GO:0021510 ! spinal cord development
relationship: results_in_development_of UBERON:0002257 ! ventral horn of spinal cord

[Term]
id: GO:0021522
name: spinal cord motor neuron differentiation
namespace: biological_process
def: "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]
is_a: GO:0021515 ! cell differentiation in spinal cord
is_a: GO:0021953 ! central nervous system neuron differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0011001 ! spinal cord motor neuron
relationship: part_of GO:0021517 ! ventral spinal cord development
relationship: results_in_acquisition_of_features_of CL:0011001 ! spinal cord motor neuron

[Term]
id: GO:0021523
name: somatic motor neuron differentiation
namespace: biological_process
def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]
is_a: GO:0021522 ! spinal cord motor neuron differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0005024 ! somatomotor neuron
relationship: results_in_acquisition_of_features_of CL:0005024 ! somatomotor neuron

[Term]
id: GO:0021532
name: neural tube patterning
namespace: biological_process
def: "The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0003002 ! regionalization
relationship: part_of GO:0021915 ! neural tube development

[Term]
id: GO:0021533
name: cell differentiation in hindbrain
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: occurs_in UBERON:0002028 ! hindbrain
relationship: in_taxon NCBITaxon:89593 {all_only="true"} ! Craniata <chordates>
relationship: occurs_in UBERON:0002028 ! hindbrain
relationship: only_in_taxon NCBITaxon:89593 ! Craniata <chordates>
relationship: part_of GO:0030902 ! hindbrain development

[Term]
id: GO:0021534
name: cell proliferation in hindbrain
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0061351 ! neural precursor cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: occurs_in UBERON:0002028 ! hindbrain
relationship: in_taxon NCBITaxon:89593 {all_only="true"} ! Craniata <chordates>
relationship: occurs_in UBERON:0002028 ! hindbrain
relationship: only_in_taxon NCBITaxon:89593 ! Craniata <chordates>
relationship: part_of GO:0030902 ! hindbrain development

[Term]
id: GO:0021535
name: cell migration in hindbrain
namespace: biological_process
def: "The orderly movement of a cell that will reside in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: occurs_in UBERON:0002028 ! hindbrain
relationship: in_taxon NCBITaxon:89593 {all_only="true"} ! Craniata <chordates>
relationship: occurs_in UBERON:0002028 ! hindbrain
relationship: only_in_taxon NCBITaxon:89593 ! Craniata <chordates>
relationship: part_of GO:0030902 ! hindbrain development

[Term]
id: GO:0021545
name: cranial nerve development
namespace: biological_process
def: "The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0021675 ! nerve development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001785 ! cranial nerve
relationship: results_in_development_of UBERON:0001785 ! cranial nerve

[Term]
id: GO:0021546
name: rhombomere development
namespace: biological_process
def: "The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001892 ! rhombomere
relationship: part_of GO:0030902 ! hindbrain development
relationship: results_in_development_of UBERON:0001892 ! rhombomere

[Term]
id: GO:0021547
name: midbrain-hindbrain boundary initiation
namespace: biological_process
def: "The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:isa_complete, GOC:jid, PMID:15541513]
synonym: "isthmus biosynthesis" RELATED [GOC:cls]
synonym: "isthmus formation" RELATED [GOC:cls]
synonym: "MHB biosynthesis" EXACT [GOC:cls]
synonym: "MHB formation" EXACT [GOC:cls]
synonym: "midbrain-hindbrain boundary biosynthesis" EXACT [GOC:cls]
synonym: "midbrain-hindbrain boundary formation" EXACT [GOC:cls]
is_a: GO:0003002 ! regionalization
is_a: GO:0048859 ! formation of anatomical boundary
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003052 ! midbrain-hindbrain boundary
relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization
relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development
relationship: results_in_formation_of_anatomical_entity UBERON:0003052 ! midbrain-hindbrain boundary

[Term]
id: GO:0021548
name: pons development
namespace: biological_process
def: "The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000988 ! pons
relationship: part_of GO:0022037 ! metencephalon development
relationship: results_in_development_of UBERON:0000988 ! pons

[Term]
id: GO:0021550
name: medulla oblongata development
namespace: biological_process
def: "The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "medulla development" RELATED [GOC:cls]
synonym: "myelencephalon development" RELATED [GOC:cls]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001896 ! medulla oblongata
relationship: part_of GO:0030902 ! hindbrain development
relationship: results_in_development_of UBERON:0001896 ! medulla oblongata

[Term]
id: GO:0021551
name: central nervous system morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001017 ! central nervous system
relationship: part_of GO:0007417 ! central nervous system development
relationship: results_in_morphogenesis_of UBERON:0001017 ! central nervous system

[Term]
id: GO:0021555
name: midbrain-hindbrain boundary morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513]
synonym: "isthmus morphogenesis" EXACT [GOC:cls]
synonym: "MHB morphogenesis" EXACT [GOC:cls]
is_a: GO:0048598 ! embryonic morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003052 ! midbrain-hindbrain boundary
relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development
relationship: results_in_morphogenesis_of UBERON:0003052 ! midbrain-hindbrain boundary

[Term]
id: GO:0021556
name: central nervous system formation
namespace: biological_process
def: "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001017 ! central nervous system
relationship: part_of GO:0021551 ! central nervous system morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001017 ! central nervous system

[Term]
id: GO:0021559
name: trigeminal nerve development
namespace: biological_process
def: "The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "CN V development" RELATED [GOC:cls]
synonym: "cranial nerve 5 development" EXACT [GOC:cls]
synonym: "cranial nerve V development" EXACT [GOC:cls]
is_a: GO:0021545 ! cranial nerve development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001645 ! trigeminal nerve
relationship: results_in_development_of UBERON:0001645 ! trigeminal nerve

[Term]
id: GO:0021575
name: hindbrain morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "rhombencephalon morphogenesis" RELATED []
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002028 ! hindbrain
relationship: part_of GO:0030902 ! hindbrain development
relationship: results_in_morphogenesis_of UBERON:0002028 ! hindbrain

[Term]
id: GO:0021576
name: hindbrain formation
namespace: biological_process
def: "The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002028 ! hindbrain
relationship: part_of GO:0021575 ! hindbrain morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002028 ! hindbrain

[Term]
id: GO:0021578
name: hindbrain maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0002028 ! hindbrain
relationship: part_of GO:0021626 ! central nervous system maturation
relationship: part_of GO:0030902 ! hindbrain development
relationship: results_in_maturation_of UBERON:0002028 ! hindbrain

[Term]
id: GO:0021579
name: medulla oblongata morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "medulla morphogenesis" RELATED []
synonym: "myelencephalon morphogenesis" RELATED []
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001896 ! medulla oblongata
relationship: part_of GO:0021550 ! medulla oblongata development
relationship: part_of GO:0021575 ! hindbrain morphogenesis
relationship: results_in_morphogenesis_of UBERON:0001896 ! medulla oblongata

[Term]
id: GO:0021580
name: medulla oblongata formation
namespace: biological_process
def: "The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "medulla biosynthesis" RELATED []
synonym: "medulla formation" RELATED []
synonym: "myelencephalon biosynthesis" RELATED []
synonym: "myelencephalon formation" RELATED []
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001896 ! medulla oblongata
relationship: part_of GO:0021576 ! hindbrain formation
relationship: part_of GO:0021579 ! medulla oblongata morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001896 ! medulla oblongata

[Term]
id: GO:0021582
name: medulla oblongata maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "medulla maturation" RELATED []
synonym: "myelencephalon maturation" RELATED []
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0001896 ! medulla oblongata
relationship: part_of GO:0021550 ! medulla oblongata development
relationship: part_of GO:0021578 ! hindbrain maturation
relationship: results_in_maturation_of UBERON:0001896 ! medulla oblongata

[Term]
id: GO:0021583
name: pons morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000988 ! pons
relationship: part_of GO:0021548 ! pons development
relationship: part_of GO:0021575 ! hindbrain morphogenesis
relationship: results_in_morphogenesis_of UBERON:0000988 ! pons

[Term]
id: GO:0021584
name: pons formation
namespace: biological_process
def: "The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000988 ! pons
relationship: part_of GO:0021576 ! hindbrain formation
relationship: part_of GO:0021583 ! pons morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0000988 ! pons

[Term]
id: GO:0021586
name: pons maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0000988 ! pons
relationship: part_of GO:0021548 ! pons development
relationship: part_of GO:0021578 ! hindbrain maturation
relationship: results_in_maturation_of UBERON:0000988 ! pons

[Term]
id: GO:0021593
name: rhombomere morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001892 ! rhombomere
relationship: part_of GO:0021546 ! rhombomere development
relationship: results_in_morphogenesis_of UBERON:0001892 ! rhombomere

[Term]
id: GO:0021594
name: rhombomere formation
namespace: biological_process
def: "The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001892 ! rhombomere
relationship: part_of GO:0021593 ! rhombomere morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001892 ! rhombomere

[Term]
id: GO:0021602
name: cranial nerve morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001785 ! cranial nerve
relationship: part_of GO:0021545 ! cranial nerve development
relationship: results_in_morphogenesis_of UBERON:0001785 ! cranial nerve

[Term]
id: GO:0021603
name: cranial nerve formation
namespace: biological_process
def: "The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001785 ! cranial nerve
relationship: part_of GO:0021602 ! cranial nerve morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001785 ! cranial nerve

[Term]
id: GO:0021605
name: cranial nerve maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0021682 ! nerve maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0001785 ! cranial nerve
relationship: part_of GO:0021545 ! cranial nerve development
relationship: results_in_maturation_of UBERON:0001785 ! cranial nerve

[Term]
id: GO:0021626
name: central nervous system maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089]
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0001017 ! central nervous system
relationship: part_of GO:0007417 ! central nervous system development
relationship: results_in_maturation_of UBERON:0001017 ! central nervous system

[Term]
id: GO:0021635
name: trigeminal nerve maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "CN V maturation" RELATED []
is_a: GO:0021605 ! cranial nerve maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0001645 ! trigeminal nerve
relationship: part_of GO:0021559 ! trigeminal nerve development
relationship: results_in_maturation_of UBERON:0001645 ! trigeminal nerve

[Term]
id: GO:0021636
name: trigeminal nerve morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "CN V morphogenesis" RELATED []
is_a: GO:0021602 ! cranial nerve morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001645 ! trigeminal nerve
relationship: part_of GO:0021559 ! trigeminal nerve development
relationship: results_in_morphogenesis_of UBERON:0001645 ! trigeminal nerve

[Term]
id: GO:0021638
name: trigeminal nerve formation
namespace: biological_process
def: "The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "CN V biosynthesis" RELATED []
synonym: "CN V formation" RELATED []
is_a: GO:0021603 ! cranial nerve formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001645 ! trigeminal nerve
relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001645 ! trigeminal nerve

[Term]
id: GO:0021654
name: rhombomere boundary formation
namespace: biological_process
def: "The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0048859 ! formation of anatomical boundary
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0018239 ! rhombomere boundary
relationship: part_of GO:0021594 ! rhombomere formation
relationship: results_in_formation_of_anatomical_entity UBERON:0018239 ! rhombomere boundary

[Term]
id: GO:0021675
name: nerve development
namespace: biological_process
def: "The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001021 ! nerve
relationship: part_of GO:0007399 ! nervous system development
relationship: results_in_development_of UBERON:0001021 ! nerve

[Term]
id: GO:0021682
name: nerve maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0001021 ! nerve
relationship: part_of GO:0021675 ! nerve development
relationship: results_in_maturation_of UBERON:0001021 ! nerve

[Term]
id: GO:0021700
name: developmental maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
subset: goslim_chembl
is_a: GO:0032502 ! developmental process

[Term]
id: GO:0021703
name: locus ceruleus development
namespace: biological_process
def: "The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "locus caeruleus development" EXACT []
synonym: "locus coeruleus development" EXACT []
is_a: GO:0048857 ! neural nucleus development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002148 ! locus ceruleus
relationship: part_of GO:0021548 ! pons development
relationship: results_in_development_of UBERON:0002148 ! locus ceruleus

[Term]
id: GO:0021704
name: locus ceruleus morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002148 ! locus ceruleus
relationship: part_of GO:0021583 ! pons morphogenesis
relationship: part_of GO:0021703 ! locus ceruleus development
relationship: results_in_morphogenesis_of UBERON:0002148 ! locus ceruleus

[Term]
id: GO:0021705
name: locus ceruleus formation
namespace: biological_process
def: "The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002148 ! locus ceruleus
relationship: part_of GO:0021584 ! pons formation
relationship: part_of GO:0021704 ! locus ceruleus morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002148 ! locus ceruleus

[Term]
id: GO:0021706
name: locus ceruleus maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0002148 ! locus ceruleus
relationship: part_of GO:0021586 ! pons maturation
relationship: part_of GO:0021703 ! locus ceruleus development
relationship: results_in_maturation_of UBERON:0002148 ! locus ceruleus

[Term]
id: GO:0021718
name: superior olivary nucleus development
namespace: biological_process
def: "The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "superior olive development" RELATED []
is_a: GO:0048857 ! neural nucleus development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0007247 ! nucleus of superior olivary complex
relationship: part_of GO:0021548 ! pons development
relationship: results_in_development_of UBERON:0007247 ! nucleus of superior olivary complex

[Term]
id: GO:0021719
name: superior olivary nucleus morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "superior olive morphogenesis" RELATED []
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0007247 ! nucleus of superior olivary complex
relationship: part_of GO:0021583 ! pons morphogenesis
relationship: part_of GO:0021718 ! superior olivary nucleus development
relationship: results_in_morphogenesis_of UBERON:0007247 ! nucleus of superior olivary complex

[Term]
id: GO:0021720
name: superior olivary nucleus formation
namespace: biological_process
def: "The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0007247 ! nucleus of superior olivary complex
relationship: part_of GO:0021584 ! pons formation
relationship: part_of GO:0021719 ! superior olivary nucleus morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0007247 ! nucleus of superior olivary complex

[Term]
id: GO:0021722
name: superior olivary nucleus maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]
synonym: "superior olive maturation" RELATED []
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0007247 ! nucleus of superior olivary complex
relationship: part_of GO:0021586 ! pons maturation
relationship: part_of GO:0021718 ! superior olivary nucleus development
relationship: results_in_maturation_of UBERON:0007247 ! nucleus of superior olivary complex

[Term]
id: GO:0021732
name: midbrain-hindbrain boundary maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513]
synonym: "isthmus maturation" RELATED []
synonym: "MHB maturation" RELATED []
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0003052 ! midbrain-hindbrain boundary
relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development
relationship: results_in_maturation_of UBERON:0003052 ! midbrain-hindbrain boundary

[Term]
id: GO:0021751
name: salivary nucleus development
namespace: biological_process
def: "The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0048857 ! neural nucleus development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004133 ! salivatory nucleus
relationship: part_of GO:0021548 ! pons development
relationship: results_in_development_of UBERON:0004133 ! salivatory nucleus

[Term]
id: GO:0021753
name: superior salivary nucleus development
namespace: biological_process
def: "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0021751 ! salivary nucleus development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002149 ! superior salivatory nucleus
relationship: results_in_development_of UBERON:0002149 ! superior salivatory nucleus

[Term]
id: GO:0021782
name: glial cell development
namespace: biological_process
def: "The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000125 ! glial cell
relationship: part_of GO:0010001 ! glial cell differentiation
relationship: results_in_development_of CL:0000125 ! glial cell

[Term]
id: GO:0021903
name: rostrocaudal neural tube patterning
namespace: biological_process
def: "The process in which the neural tube is divided into specific regions along the rostrocaudal axis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]
synonym: "anterior-posterior neural tube patterning" RELATED [GOC:dph]
is_a: GO:0009952 ! anterior/posterior pattern specification
relationship: part_of GO:0021532 ! neural tube patterning

[Term]
id: GO:0021906
name: hindbrain-spinal cord boundary formation
namespace: biological_process
def: "The process whose specific outcome is the formation of the hindbrain-spinal cord boundary." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]
is_a: GO:0048859 ! formation of anatomical boundary
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005076 ! hindbrain-spinal cord boundary
relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning
relationship: results_in_formation_of_anatomical_entity UBERON:0005076 ! hindbrain-spinal cord boundary

[Term]
id: GO:0021915
name: neural tube development
namespace: biological_process
def: "The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0035295 ! tube development
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001049 ! neural tube
relationship: part_of GO:0007399 ! nervous system development
relationship: part_of GO:0043009 ! chordate embryonic development
relationship: results_in_development_of UBERON:0001049 ! neural tube

[Term]
id: GO:0021953
name: central nervous system neuron differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0030182 ! neuron differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:2000029 ! central nervous system neuron
relationship: part_of GO:0007417 ! central nervous system development
relationship: results_in_acquisition_of_features_of CL:2000029 ! central nervous system neuron

[Term]
id: GO:0021954
name: central nervous system neuron development
namespace: biological_process
def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0048666 ! neuron development
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:2000029 ! central nervous system neuron
relationship: part_of GO:0021953 ! central nervous system neuron differentiation
relationship: results_in_development_of CL:2000029 ! central nervous system neuron

[Term]
id: GO:0021990
name: neural plate formation
namespace: biological_process
def: "The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878932437, ISBN:0878932585, PMID:15806586]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003075 ! neural plate
relationship: part_of GO:0001839 ! neural plate morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0003075 ! neural plate

[Term]
id: GO:0021999
name: neural plate anterior/posterior regionalization
namespace: biological_process
def: "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
synonym: "neural plate anterior/posterior pattern formation" RELATED [GOC:dph]
is_a: GO:0009952 ! anterior/posterior pattern specification
is_a: GO:0060897 ! neural plate regionalization

[Term]
id: GO:0022008
name: neurogenesis
namespace: biological_process
def: "Generation of cells within the nervous system." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid]
synonym: "nervous system cell generation" EXACT systematic_synonym []
synonym: "neural cell differentiation" RELATED [GOC:BHF, GOC:dph]
xref: Wikipedia:Neurogenesis
is_a: GO:0030154 ! cell differentiation
relationship: part_of GO:0007399 ! nervous system development

[Term]
id: GO:0022009
name: central nervous system vasculogenesis
namespace: biological_process
def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0001570 ! vasculogenesis
intersection_of: GO:0001570 ! vasculogenesis
intersection_of: results_in_maturation_of UBERON:0001017 ! central nervous system
relationship: results_in_maturation_of UBERON:0001017 ! central nervous system
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21480" xsd:anyURI

[Term]
id: GO:0022035
name: rhombomere cell migration
namespace: biological_process
def: "The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15629700]
is_a: GO:0021535 ! cell migration in hindbrain
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_transport_to_from_or_in UBERON:0001892 ! rhombomere
relationship: part_of GO:0021546 ! rhombomere development
relationship: results_in_transport_to_from_or_in UBERON:0001892 ! rhombomere

[Term]
id: GO:0022037
name: metencephalon development
namespace: biological_process
def: "The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001895 ! metencephalon
relationship: part_of GO:0030902 ! hindbrain development
relationship: results_in_development_of UBERON:0001895 ! metencephalon

[Term]
id: GO:0022402
name: cell cycle process
namespace: biological_process
def: "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." [GOC:isa_complete, GOC:mtg_cell_cycle]
subset: gocheck_do_not_annotate
is_a: GO:0009987 ! cellular process
intersection_of: GO:0009987 ! cellular process
intersection_of: part_of GO:0007049 ! cell cycle
relationship: part_of GO:0007049 ! cell cycle

[Term]
id: GO:0022406
name: membrane docking
namespace: biological_process
def: "The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere." [GOC:isa_complete, PMID:27875684]
subset: goslim_pir
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0022407
name: regulation of cell-cell adhesion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." [GOC:isa_complete]
is_a: GO:0030155 ! regulation of cell adhesion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0098609 ! cell-cell adhesion
relationship: regulates GO:0098609 ! cell-cell adhesion

[Term]
id: GO:0022408
name: negative regulation of cell-cell adhesion
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." [GOC:isa_complete]
synonym: "down regulation of cell-cell adhesion" EXACT []
synonym: "down-regulation of cell-cell adhesion" EXACT []
synonym: "downregulation of cell-cell adhesion" EXACT []
synonym: "inhibition of cell-cell adhesion" NARROW []
is_a: GO:0007162 ! negative regulation of cell adhesion
is_a: GO:0022407 ! regulation of cell-cell adhesion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0098609 ! cell-cell adhesion
relationship: negatively_regulates GO:0098609 ! cell-cell adhesion

[Term]
id: GO:0022409
name: positive regulation of cell-cell adhesion
namespace: biological_process
def: "Any process that activates or increases the rate or extent of cell adhesion to another cell." [GOC:isa_complete]
synonym: "activation of cell-cell adhesion" NARROW []
synonym: "stimulation of cell-cell adhesion" NARROW []
synonym: "up regulation of cell-cell adhesion" EXACT []
synonym: "up-regulation of cell-cell adhesion" EXACT []
synonym: "upregulation of cell-cell adhesion" EXACT []
is_a: GO:0022407 ! regulation of cell-cell adhesion
is_a: GO:0045785 ! positive regulation of cell adhesion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0098609 ! cell-cell adhesion
relationship: positively_regulates GO:0098609 ! cell-cell adhesion

[Term]
id: GO:0022411
name: cellular component disassembly
namespace: biological_process
alt_id: GO:0071845
def: "A cellular process that results in the breakdown of a cellular component." [GOC:isa_complete]
subset: goslim_pir
synonym: "cell structure disassembly" EXACT []
synonym: "cellular component disassembly at cellular level" EXACT []
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_disassembly_of GO:0005575 ! cellular_component
disjoint_from: GO:0022607 ! cellular component assembly
relationship: results_in_disassembly_of GO:0005575 ! cellular_component

[Term]
id: GO:0022412
name: cellular process involved in reproduction in multicellular organism
namespace: biological_process
def: "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." [GOC:isa_complete]
synonym: "reproductive cellular process in multicellular organism" EXACT []
is_a: GO:0009987 ! cellular process
is_a: GO:0022414 ! reproductive process
intersection_of: GO:0009987 ! cellular process
intersection_of: part_of GO:0032504 ! multicellular organism reproduction
relationship: part_of GO:0032504 ! multicellular organism reproduction

[Term]
id: GO:0022414
name: reproductive process
namespace: biological_process
alt_id: GO:0044702
def: "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:dph, GOC:isa_complete]
subset: goslim_generic
synonym: "single organism reproductive process" RELATED []
is_a: GO:0008150 ! biological process
intersection_of: GO:0008150 ! biological process
intersection_of: part_of GO:0000003 ! reproduction
relationship: part_of GO:0000003 ! reproduction
created_by: jl
creation_date: 2012-09-19T15:56:06Z

[Term]
id: GO:0022600
name: digestive system process
namespace: biological_process
def: "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, GOC:jid, GOC:mtg_cardio]
subset: goslim_generic
is_a: GO:0003008 ! system process
intersection_of: GO:0003008 ! system process
intersection_of: part_of GO:0007586 ! digestion
relationship: part_of GO:0007586 ! digestion

[Term]
id: GO:0022602
name: ovulation cycle process
namespace: biological_process
def: "A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [GOC:isa_complete]
synonym: "estrous cycle process" RELATED []
synonym: "menstrual cycle process" RELATED []
is_a: GO:0022414 ! reproductive process
is_a: GO:0048511 ! rhythmic process
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of GO:0042698 ! ovulation cycle

[Term]
id: GO:0022603
name: regulation of anatomical structure morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." [GOC:mah]
synonym: "regulation of morphogenesis" EXACT []
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009653 ! anatomical structure morphogenesis
relationship: regulates GO:0009653 ! anatomical structure morphogenesis

[Term]
id: GO:0022604
name: regulation of cell morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized." [GOC:isa_complete]
synonym: "negative regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb]
synonym: "positive regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb]
synonym: "regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0000902 ! cell morphogenesis
relationship: regulates GO:0000902 ! cell morphogenesis

[Term]
id: GO:0022607
name: cellular component assembly
namespace: biological_process
alt_id: GO:0071844
def: "The aggregation, arrangement and bonding together of a cellular component." [GOC:isa_complete]
subset: goslim_chembl
subset: goslim_pir
synonym: "cell structure assembly" EXACT []
synonym: "cellular component assembly at cellular level" EXACT []
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_assembly_of GO:0005575 ! cellular_component
relationship: part_of GO:0044085 ! cellular component biogenesis
relationship: results_in_assembly_of GO:0005575 ! cellular_component

[Term]
id: GO:0022612
name: gland morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a gland are generated and organized." [GOC:isa_complete]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002530 ! gland
relationship: part_of GO:0048732 ! gland development
relationship: results_in_morphogenesis_of UBERON:0002530 ! gland

[Term]
id: GO:0022613
name: ribonucleoprotein complex biogenesis
namespace: biological_process
def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex." [GOC:isa_complete, GOC:mah]
synonym: "ribonucleoprotein complex biogenesis and assembly" EXACT [GOC:mah]
synonym: "RNA-protein complex biogenesis" EXACT [GOC:mah]
is_a: GO:0044085 ! cellular component biogenesis

[Term]
id: GO:0022617
name: extracellular matrix disassembly
namespace: biological_process
def: "A process that results in the breakdown of the extracellular matrix." [GOC:jid]
is_a: GO:0022411 ! cellular component disassembly
is_a: GO:0030198 ! extracellular matrix organization
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0031012 ! extracellular matrix
relationship: results_in_disassembly_of GO:0031012 ! extracellular matrix

[Term]
id: GO:0022618
name: protein-RNA complex assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." [GOC:jl]
subset: goslim_chembl
synonym: "ribonucleoprotein complex assembly" EXACT []
synonym: "RNA-protein complex assembly" EXACT []
synonym: "RNP complex assembly" EXACT []
is_a: GO:0065003 ! protein-containing complex assembly
is_a: GO:0071826 ! protein-RNA complex organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:1990904 ! ribonucleoprotein complex
relationship: part_of GO:0022613 ! ribonucleoprotein complex biogenesis
relationship: results_in_assembly_of GO:1990904 ! ribonucleoprotein complex

[Term]
id: GO:0022804
name: active transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729]
synonym: "active carrier activity" EXACT []
synonym: "carrier activity" EXACT []
synonym: "permease activity" EXACT []
synonym: "pump activity" EXACT []
is_a: GO:0022857 ! transmembrane transporter activity

[Term]
id: GO:0022853
name: active monoatomic ion transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729]
synonym: "active ion transmembrane transporter activity" BROAD []
is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity
is_a: GO:0022804 ! active transmembrane transporter activity
intersection_of: GO:0022804 ! active transmembrane transporter activity
intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI

[Term]
id: GO:0022857
name: transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0005386
alt_id: GO:0015563
alt_id: GO:0015646
alt_id: GO:0022891
alt_id: GO:0022892
def: "Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other." [GOC:jid, GOC:mtg_transport, ISBN:0815340729]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_yeast
synonym: "substrate-specific transmembrane transporter activity" RELATED []
synonym: "substrate-specific transporter activity" RELATED []
synonym: "uptake permease activity" RELATED []
synonym: "uptake transmembrane transporter activity" RELATED []
xref: Reactome:R-HSA-1236947 "Egress of internalized antigen to the cytosol via sec61"
xref: Reactome:R-HSA-429036 "SLC2A9 transports Fru, Glc, urate"
xref: Reactome:R-HSA-5638209 "Defective SLC2A9 does not transport Fru, Glc, urate"
xref: Reactome:R-HSA-5671707 "Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA"
xref: Reactome:R-HSA-6784434 "An unknown carrier transports cytosolic glyoxylate to the peroxisome"
xref: Reactome:R-HSA-6784436 "An unknown carrier transports mitochondrial glyoxylate to the cytosol"
is_a: GO:0005215 ! transporter activity
intersection_of: GO:0005215 ! transporter activity
intersection_of: results_in_transport_across GO:0016020 ! membrane
relationship: part_of GO:0055085 ! transmembrane transport
relationship: results_in_transport_across GO:0016020 ! membrane

[Term]
id: GO:0022884
name: macromolecule transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of a macromolecule from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729]
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:33694 ! biomacromolecule
relationship: has_primary_input CHEBI:33694 ! biomacromolecule

[Term]
id: GO:0022890
name: inorganic cation transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0015077
alt_id: GO:0015082
alt_id: GO:0072509
alt_id: GO:0072510
def: "Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
synonym: "di-, tri-valent inorganic cation transmembrane transporter activity" NARROW [GOC:mah]
synonym: "divalent inorganic cation transmembrane transporter activity" NARROW []
synonym: "monovalent inorganic cation transmembrane transporter activity" NARROW []
synonym: "trivalent inorganic cation transmembrane transporter activity" NARROW []
is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:36915 ! inorganic cation
relationship: has_primary_input CHEBI:36915 ! inorganic cation

[Term]
id: GO:0022898
name: regulation of transmembrane transporter activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of transmembrane transporter activity." [GOC:dph, GOC:mtg_cardio, GOC:mtg_transport]
subset: gocheck_do_not_annotate
is_a: GO:0032409 ! regulation of transporter activity
is_a: GO:0034762 ! regulation of transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0022857 ! transmembrane transporter activity
relationship: regulates GO:0022857 ! transmembrane transporter activity

[Term]
id: GO:0023019
name: signal transduction involved in regulation of gene expression
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another." [GOC:mtg_signal]
synonym: "regulation of gene expression as a consequence of signal transmission" RELATED [GOC:bf]
is_a: GO:0007165 ! signal transduction
intersection_of: GO:0007165 ! signal transduction
intersection_of: part_of GO:0010468 ! regulation of gene expression
relationship: part_of GO:0010468 ! regulation of gene expression
creation_date: 2010-02-16T09:30:50Z

[Term]
id: GO:0023051
name: regulation of signaling
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a signaling process." [GOC:mtg_signal]
synonym: "regulation of signaling process" RELATED [GOC:bf]
synonym: "regulation of signalling process" RELATED [GOC:mah]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0023052 ! signaling
relationship: regulates GO:0023052 ! signaling
creation_date: 2010-02-16T09:30:50Z

[Term]
id: GO:0023052
name: signaling
namespace: biological_process
alt_id: GO:0023046
alt_id: GO:0044700
def: "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling]
comment: Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change.
subset: goslim_agr
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_mouse
subset: goslim_pombe
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "biological signaling" EXACT []
synonym: "signaling process" EXACT []
synonym: "signalling" EXACT []
synonym: "signalling process" RELATED [GOC:mah]
synonym: "single organism signaling" RELATED []
is_a: GO:0050789 ! regulation of biological process
created_by: jl
creation_date: 2010-02-16T09:30:50Z

[Term]
id: GO:0023056
name: positive regulation of signaling
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." [GOC:mtg_signal]
synonym: "positive regulation of signaling process" RELATED [GOC:bf]
synonym: "positive regulation of signalling process" EXACT [GOC:mah]
is_a: GO:0023051 ! regulation of signaling
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0023052 ! signaling
relationship: positively_regulates GO:0023052 ! signaling
creation_date: 2010-02-16T09:30:50Z

[Term]
id: GO:0023057
name: negative regulation of signaling
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." [GOC:mtg_signal]
synonym: "negative regulation of signaling process" RELATED [GOC:bf]
synonym: "negative regulation of signalling process" RELATED [GOC:mah]
is_a: GO:0023051 ! regulation of signaling
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0023052 ! signaling
relationship: negatively_regulates GO:0023052 ! signaling
creation_date: 2010-02-16T09:30:50Z

[Term]
id: GO:0023061
name: signal release
namespace: biological_process
def: "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." [GOC:mtg_signal]
synonym: "signal secretion" EXACT [GOC:bf]
is_a: GO:0032940 ! secretion by cell
intersection_of: GO:0032940 ! secretion by cell
intersection_of: part_of GO:0007267 ! cell-cell signaling
relationship: part_of GO:0007267 ! cell-cell signaling
creation_date: 2010-02-16T09:30:50Z

[Term]
id: GO:0030001
name: metal ion transport
namespace: biological_process
alt_id: GO:0070838
alt_id: GO:0070839
def: "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "divalent metal ion export" NARROW []
synonym: "divalent metal ion transport" NARROW []
synonym: "heavy metal ion transport" NARROW []
synonym: "metal ion export" NARROW []
is_a: GO:0006812 ! monoatomic cation transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:25213 ! metal cation
relationship: has_primary_input CHEBI:25213 ! metal cation
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23033" xsd:anyURI
created_by: mah
creation_date: 2009-07-31T01:07:46Z

[Term]
id: GO:0030010
name: establishment of cell polarity
namespace: biological_process
alt_id: GO:0000283
alt_id: GO:0030468
def: "The specification and formation of anisotropic intracellular organization or cell growth patterns." [GOC:mah]
synonym: "bud site selection/establishment of cell polarity" NARROW []
synonym: "cell polarization" EXACT []
is_a: GO:0007163 ! establishment or maintenance of cell polarity

[Term]
id: GO:0030016
name: myofibril
namespace: cellular_component
def: "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [ISBN:0815316194]
xref: Wikipedia:Myofibril
is_a: GO:0043292 ! contractile fiber
intersection_of: GO:0043292 ! contractile fiber
intersection_of: part_of CL:0000737 ! striated muscle cell
relationship: part_of CL:0000737 ! striated muscle cell

[Term]
id: GO:0030017
name: sarcomere
namespace: cellular_component
def: "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [ISBN:0815316194]
xref: Wikipedia:Sarcomere
is_a: GO:0110165 ! cellular anatomical entity
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: part_of GO:0030016 ! myofibril

[Term]
id: GO:0030029
name: actin filament-based process
namespace: biological_process
def: "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." [GOC:mah]
synonym: "microfilament-based process" RELATED []
is_a: GO:0009987 ! cellular process
intersection_of: GO:0009987 ! cellular process
intersection_of: process_has_causal_agent GO:0005884 ! actin filament
relationship: process_has_causal_agent GO:0005884 ! actin filament

[Term]
id: GO:0030030
name: cell projection organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/]
subset: goslim_prokaryote
synonym: "cell projection organisation" EXACT []
synonym: "cell projection organization and biogenesis" RELATED [GOC:mah]
synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0042995 ! cell projection
relationship: results_in_organization_of GO:0042995 ! cell projection
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26279" xsd:anyURI

[Term]
id: GO:0030031
name: cell projection assembly
namespace: biological_process
def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/]
synonym: "cell projection biogenesis" RELATED [GOC:mah]
synonym: "formation of a cell surface projection" EXACT []
is_a: GO:0022607 ! cellular component assembly
is_a: GO:0030030 ! cell projection organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0042995 ! cell projection
relationship: results_in_assembly_of GO:0042995 ! cell projection

[Term]
id: GO:0030033
name: microvillus assembly
namespace: biological_process
def: "Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah, ISBN:0815316194]
synonym: "microvillus biogenesis" RELATED [GOC:mah]
is_a: GO:0032528 ! microvillus organization
is_a: GO:0120031 ! plasma membrane bounded cell projection assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0005902 ! microvillus
relationship: results_in_assembly_of GO:0005902 ! microvillus

[Term]
id: GO:0030036
name: actin cytoskeleton organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:dph, GOC:jl, GOC:mah]
subset: goslim_pombe
synonym: "actin cytoskeleton organisation" EXACT []
synonym: "actin cytoskeleton organization and biogenesis" RELATED [GOC:mah]
synonym: "actin modulating activity" RELATED []
is_a: GO:0007010 ! cytoskeleton organization
is_a: GO:0030029 ! actin filament-based process
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0015629 ! actin cytoskeleton
relationship: results_in_organization_of GO:0015629 ! actin cytoskeleton
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23114" xsd:anyURI

[Term]
id: GO:0030048
name: actin filament-based movement
namespace: biological_process
def: "Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GOC:BHF, GOC:mah]
is_a: GO:0030029 ! actin filament-based process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI

[Term]
id: GO:0030050
name: vesicle transport along actin filament
namespace: biological_process
def: "Movement of a vesicle along an actin filament, mediated by motor proteins." [GOC:mah]
is_a: GO:0030048 ! actin filament-based movement
is_a: GO:0099515 ! actin filament-based transport
is_a: GO:0099518 ! vesicle cytoskeletal trafficking
intersection_of: GO:0046907 ! intracellular transport
intersection_of: has_primary_input GO:0031982 ! vesicle
intersection_of: results_in_transport_along GO:0005884 ! actin filament

[Term]
id: GO:0030054
name: cell junction
namespace: cellular_component
def: "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella." [GOC:aruk, GOC:bc, GOC:mah, http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html, ISBN:0198506732, PMID:26820516, PMID:28096264]
subset: goslim_agr
subset: goslim_drosophila
subset: goslim_flybase_ribbon
xref: Wikipedia:Cell_junction
is_a: GO:0110165 ! cellular anatomical entity
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0030072
name: peptide hormone secretion
namespace: biological_process
def: "The regulated release of a peptide hormone from a cell." [GOC:mah]
is_a: GO:0002790 ! peptide secretion
is_a: GO:0046879 ! hormone secretion
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input CHEBI:25905 ! peptide hormone
relationship: has_primary_input CHEBI:25905 ! peptide hormone

[Term]
id: GO:0030073
name: insulin secretion
namespace: biological_process
def: "The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects." [GOC:mah, ISBN:0198506732]
is_a: GO:0009306 ! protein secretion
is_a: GO:0030072 ! peptide hormone secretion
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input PR:000009054 ! insulin gene translation product
relationship: has_primary_input PR:000009054 ! insulin gene translation product
relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/11255#issuecomment-426191045" xsd:anyURI

[Term]
id: GO:0030097
name: hemopoiesis
namespace: biological_process
def: "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." [GOC:dgh, ISBN:0198506732]
synonym: "blood cell biosynthesis" EXACT []
synonym: "blood cell formation" EXACT []
synonym: "haemopoiesis" EXACT []
synonym: "hematopoiesis" EXACT []
xref: Wikipedia:Haematopoiesis
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000988 ! hematopoietic cell
relationship: results_in_development_of CL:0000988 ! hematopoietic cell
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22178" xsd:anyURI

[Term]
id: GO:0030098
name: lymphocyte differentiation
namespace: biological_process
alt_id: GO:0046650
def: "The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:go_curators]
comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
synonym: "lymphocyte cell differentiation" EXACT []
synonym: "lymphocyte development" RELATED [GOC:add]
synonym: "lymphocytic blood cell differentiation" EXACT []
is_a: GO:0046649 ! lymphocyte activation
is_a: GO:1903131 ! mononuclear cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000542 ! lymphocyte
relationship: results_in_acquisition_of_features_of CL:0000542 ! lymphocyte

[Term]
id: GO:0030099
name: myeloid cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages." [GOC:add, ISBN:0781735149]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000763 ! myeloid cell
relationship: part_of GO:0030097 ! hemopoiesis
relationship: results_in_acquisition_of_features_of CL:0000763 ! myeloid cell

[Term]
id: GO:0030100
name: regulation of endocytosis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of endocytosis." [GOC:go_curators]
is_a: GO:0051128 ! regulation of cellular component organization
is_a: GO:0060627 ! regulation of vesicle-mediated transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006897 ! endocytosis
relationship: regulates GO:0006897 ! endocytosis

[Term]
id: GO:0030133
name: transport vesicle
namespace: cellular_component
def: "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell." [GOC:mah, PMID:22160157]
comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'.
synonym: "constitutive secretory pathway transport vesicle" EXACT []
synonym: "Golgi to vacuole transport vesicle" NARROW []
synonym: "Golgi-vacuole transport vesicle" NARROW []
synonym: "secretory vesicle" RELATED []
xref: NIF_Subcellular:sao885490876
is_a: GO:0031410 ! cytoplasmic vesicle
relationship: part_of GO:0012505 ! endomembrane system

[Term]
id: GO:0030141
name: secretory granule
namespace: cellular_component
def: "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules." [GOC:mah, ISBN:0198506732]
comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'.
synonym: "secretory vesicle" BROAD []
is_a: GO:0099503 ! secretory vesicle
relationship: part_of GO:0012505 ! endomembrane system
property_value: RO:0002161 NCBITaxon:4890

[Term]
id: GO:0030154
name: cell differentiation
namespace: biological_process
def: "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732]
subset: goslim_agr
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_mouse
subset: goslim_plant
xref: Wikipedia:Cellular_differentiation
is_a: GO:0048869 ! cellular developmental process
intersection_of: GO:0048869 ! cellular developmental process
intersection_of: results_in_acquisition_of_features_of CL:0000000 ! cell
relationship: results_in_acquisition_of_features_of CL:0000000 ! cell
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI

[Term]
id: GO:0030155
name: regulation of cell adhesion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." [GOC:mah]
synonym: "cell adhesion receptor regulator activity" RELATED []
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007155 ! cell adhesion
relationship: regulates GO:0007155 ! cell adhesion

[Term]
id: GO:0030163
name: protein catabolic process
namespace: biological_process
alt_id: GO:0044254
alt_id: GO:0044257
def: "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:mah]
comment: This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children.
subset: goslim_candida
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pombe
subset: goslim_prokaryote
synonym: "cellular protein breakdown" EXACT []
synonym: "cellular protein catabolic process" EXACT []
synonym: "cellular protein catabolism" EXACT []
synonym: "cellular protein degradation" EXACT []
synonym: "multicellular organismal protein catabolic process" NARROW []
synonym: "pheromone catabolic process" RELATED []
synonym: "pheromone catabolism" RELATED []
synonym: "protein breakdown" EXACT []
synonym: "protein catabolism" EXACT []
synonym: "protein degradation" EXACT []
xref: Wikipedia:Protein_catabolism
is_a: GO:0019538 ! protein metabolic process
is_a: GO:1901565 ! organonitrogen compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input PR:000000001 ! protein
relationship: has_primary_input PR:000000001 ! protein
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI

[Term]
id: GO:0030182
name: neuron differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron." [GOC:mah]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000540 ! neuron
relationship: part_of GO:0048699 ! generation of neurons
relationship: results_in_acquisition_of_features_of CL:0000540 ! neuron

[Term]
id: GO:0030198
name: extracellular matrix organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix." [GOC:mah]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
synonym: "extracellular matrix organisation" EXACT []
synonym: "extracellular matrix organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0043062 ! extracellular structure organization
is_a: GO:0045229 ! external encapsulating structure organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0031012 ! extracellular matrix
relationship: results_in_organization_of GO:0031012 ! extracellular matrix

[Term]
id: GO:0030199
name: collagen fibril organization
namespace: biological_process
def: "Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix." [GOC:mah, ISBN:0815316194]
synonym: "collagen fibril organisation" EXACT []
synonym: "fibrillar collagen organization" EXACT [GOC:mah]
is_a: GO:0030198 ! extracellular matrix organization
is_a: GO:0097435 ! supramolecular fiber organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0098643 ! banded collagen fibril
relationship: results_in_organization_of GO:0098643 ! banded collagen fibril
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0030203
name: glycosaminoglycan metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." [ISBN:0192800981]
synonym: "glycosaminoglycan metabolism" EXACT []
is_a: GO:0006022 ! aminoglycan metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:18085 ! glycosaminoglycan
relationship: has_primary_input_or_output CHEBI:18085 ! glycosaminoglycan

[Term]
id: GO:0030212
name: hyaluronan metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732]
synonym: "hyaluronan metabolism" EXACT []
is_a: GO:1903510 ! mucopolysaccharide metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:16336 ! hyaluronic acid
relationship: has_primary_input_or_output CHEBI:16336 ! hyaluronic acid

[Term]
id: GO:0030213
name: hyaluronan biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732]
synonym: "hyaluronan anabolism" EXACT []
synonym: "hyaluronan biosynthesis" EXACT []
synonym: "hyaluronan formation" EXACT []
synonym: "hyaluronan synthesis" EXACT []
is_a: GO:0006024 ! glycosaminoglycan biosynthetic process
is_a: GO:0030212 ! hyaluronan metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:16336 ! hyaluronic acid
relationship: has_primary_output CHEBI:16336 ! hyaluronic acid

[Term]
id: GO:0030214
name: hyaluronan catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732]
synonym: "hyaluronan breakdown" EXACT []
synonym: "hyaluronan catabolism" EXACT []
synonym: "hyaluronan degradation" EXACT []
is_a: GO:0006027 ! glycosaminoglycan catabolic process
is_a: GO:0030212 ! hyaluronan metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:16336 ! hyaluronic acid
relationship: has_primary_input CHEBI:16336 ! hyaluronic acid

[Term]
id: GO:0030217
name: T cell differentiation
namespace: biological_process
alt_id: GO:0042112
alt_id: GO:0046652
def: "The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex." [GO_REF:0000022, GOC:jid, GOC:mah]
comment: Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
synonym: "T cell development" RELATED [GOC:add]
synonym: "T lymphocyte differentiation" EXACT []
synonym: "T-cell differentiation" EXACT []
synonym: "T-lymphocyte differentiation" EXACT []
is_a: GO:0030098 ! lymphocyte differentiation
is_a: GO:0042110 ! T cell activation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000084 ! T cell
relationship: results_in_acquisition_of_features_of CL:0000084 ! T cell

[Term]
id: GO:0030218
name: erythrocyte differentiation
namespace: biological_process
def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte." [GOC:mah]
synonym: "erythrocyte cell differentiation" EXACT []
synonym: "erythropoiesis" EXACT [GOC:add, GOC:dph]
synonym: "RBC differentiation" EXACT [CL:0000232]
synonym: "red blood cell differentiation" EXACT [CL:0000232]
xref: Wikipedia:Erythropoiesis
is_a: GO:0030099 ! myeloid cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000232 ! erythrocyte
relationship: part_of GO:0034101 ! erythrocyte homeostasis
relationship: results_in_acquisition_of_features_of CL:0000232 ! erythrocyte

[Term]
id: GO:0030219
name: megakaryocyte differentiation
namespace: biological_process
def: "The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte." [GOC:mah]
synonym: "megakaryocyte cell differentiation" EXACT []
is_a: GO:0030099 ! myeloid cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000556 ! megakaryocyte
relationship: results_in_acquisition_of_features_of CL:0000556 ! megakaryocyte

[Term]
id: GO:0030239
name: myofibril assembly
namespace: biological_process
def: "Formation of myofibrils, the repeating units of striated muscle." [GOC:mah]
is_a: GO:0010927 ! cellular component assembly involved in morphogenesis
is_a: GO:0031032 ! actomyosin structure organization
is_a: GO:0097435 ! supramolecular fiber organization
is_a: GO:0140694 ! non-membrane-bounded organelle assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0030016 ! myofibril
relationship: part_of GO:0055002 ! striated muscle cell development
relationship: results_in_assembly_of GO:0030016 ! myofibril

[Term]
id: GO:0030261
name: chromosome condensation
namespace: biological_process
alt_id: GO:0000068
def: "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:mah, ISBN:0815316194]
synonym: "DNA condensation" BROAD [Wikipedia:DNA_condensation]
synonym: "eukaryotic chromosome condensation" EXACT [GOC:bf]
synonym: "nuclear chromosome condensation" EXACT [GOC:bf]
is_a: GO:0051276 ! chromosome organization

[Term]
id: GO:0030262
name: apoptotic nuclear changes
namespace: biological_process
def: "Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis." [GOC:mah, GOC:mtg_apoptosis]
synonym: "apoptotic nuclear change" NARROW []
is_a: GO:0006921 ! cellular component disassembly involved in execution phase of apoptosis

[Term]
id: GO:0030263
name: apoptotic chromosome condensation
namespace: biological_process
def: "The compaction of chromatin during apoptosis." [GOC:mah]
synonym: "pyknosis" EXACT []
xref: Wikipedia:Pyknosis
is_a: GO:0030261 ! chromosome condensation
relationship: part_of GO:0030262 ! apoptotic nuclear changes

[Term]
id: GO:0030264
name: nuclear fragmentation involved in apoptotic nuclear change
namespace: biological_process
def: "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976]
synonym: "apoptotic nuclear fragmentation" EXACT []
synonym: "nuclear fragmentation during apoptosis" RELATED [GOC:dph, GOC:tb]
synonym: "nucleus fragmentation" EXACT []
is_a: GO:0071763 ! nuclear membrane organization
intersection_of: GO:0071763 ! nuclear membrane organization
intersection_of: part_of GO:0030262 ! apoptotic nuclear changes
relationship: part_of GO:0030262 ! apoptotic nuclear changes

[Term]
id: GO:0030278
name: regulation of ossification
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators]
synonym: "regulation of bone biosynthesis" EXACT []
synonym: "regulation of bone formation" EXACT []
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001503 ! ossification
relationship: regulates GO:0001503 ! ossification

[Term]
id: GO:0030279
name: negative regulation of ossification
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators]
synonym: "down regulation of ossification" EXACT []
synonym: "down-regulation of ossification" EXACT []
synonym: "downregulation of ossification" EXACT []
synonym: "inhibition of ossification" NARROW []
synonym: "negative regulation of bone biosynthesis" EXACT []
synonym: "negative regulation of bone formation" EXACT []
is_a: GO:0030278 ! regulation of ossification
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001503 ! ossification
relationship: negatively_regulates GO:0001503 ! ossification

[Term]
id: GO:0030307
name: positive regulation of cell growth
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, extent or direction of cell growth." [GOC:go_curators]
synonym: "activation of cell growth" NARROW []
synonym: "stimulation of cell growth" NARROW []
synonym: "up regulation of cell growth" EXACT []
synonym: "up-regulation of cell growth" EXACT []
synonym: "upregulation of cell growth" EXACT []
is_a: GO:0001558 ! regulation of cell growth
is_a: GO:0045927 ! positive regulation of growth
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0016049 ! cell growth
relationship: positively_regulates GO:0016049 ! cell growth

[Term]
id: GO:0030308
name: negative regulation of cell growth
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth." [GOC:go_curators]
synonym: "down regulation of cell growth" EXACT []
synonym: "down-regulation of cell growth" EXACT []
synonym: "downregulation of cell growth" EXACT []
synonym: "inhibition of cell growth" NARROW []
is_a: GO:0001558 ! regulation of cell growth
is_a: GO:0045926 ! negative regulation of growth
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0016049 ! cell growth
relationship: negatively_regulates GO:0016049 ! cell growth

[Term]
id: GO:0030312
name: external encapsulating structure
namespace: cellular_component
def: "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space." [GOC:go_curators]
comment: The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'.
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pir
subset: goslim_plant
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of CL:0000000 ! cell
relationship: part_of GO:0071944 ! cell periphery

[Term]
id: GO:0030317
name: flagellated sperm motility
namespace: biological_process
alt_id: GO:0097724
alt_id: GO:1905419
def: "The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm." [GO_REF:0000060, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:26680031]
synonym: "flagellated sperm movement" EXACT []
synonym: "sperm flagellum movement" EXACT [GOC:cilia, GOC:krc]
synonym: "sperm flagellum movement involved in flagellated sperm motility" EXACT []
synonym: "sperm flagellum movement involved in flagellated sperm movement" EXACT [GOC:TermGenie]
synonym: "sperm motility" BROAD []
synonym: "sperm movement" BROAD []
xref: Wikipedia:Sperm_motility
is_a: GO:0060285 ! cilium-dependent cell motility
is_a: GO:0060294 ! cilium movement involved in cell motility
is_a: GO:0097722 ! sperm motility
intersection_of: GO:0060285 ! cilium-dependent cell motility
intersection_of: results_in_movement_of CL:0000019 ! sperm

[Term]
id: GO:0030323
name: respiratory tube development
namespace: biological_process
def: "The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract." [GOC:jid]
is_a: GO:0035295 ! tube development
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000117 ! respiratory tube
relationship: results_in_development_of UBERON:0000117 ! respiratory tube

[Term]
id: GO:0030324
name: lung development
namespace: biological_process
def: "The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:jid, UBERON:0002048]
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002048 ! lung
relationship: part_of GO:0030323 ! respiratory tube development
relationship: part_of GO:0060541 ! respiratory system development
relationship: results_in_development_of UBERON:0002048 ! lung

[Term]
id: GO:0030334
name: regulation of cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell migration." [GOC:go_curators]
is_a: GO:2000145 ! regulation of cell motility
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016477 ! cell migration
relationship: regulates GO:0016477 ! cell migration
property_value: RO:0002161 NCBITaxon:4890

[Term]
id: GO:0030335
name: positive regulation of cell migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell migration." [GOC:go_curators]
synonym: "activation of cell migration" NARROW []
synonym: "stimulation of cell migration" NARROW []
synonym: "up regulation of cell migration" EXACT []
synonym: "up-regulation of cell migration" EXACT []
synonym: "upregulation of cell migration" EXACT []
is_a: GO:0030334 ! regulation of cell migration
is_a: GO:2000147 ! positive regulation of cell motility
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0016477 ! cell migration
relationship: positively_regulates GO:0016477 ! cell migration

[Term]
id: GO:0030336
name: negative regulation of cell migration
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." [GOC:go_curators]
synonym: "down regulation of cell migration" EXACT []
synonym: "down-regulation of cell migration" EXACT []
synonym: "downregulation of cell migration" EXACT []
synonym: "inhibition of cell migration" NARROW []
is_a: GO:0030334 ! regulation of cell migration
is_a: GO:2000146 ! negative regulation of cell motility
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0016477 ! cell migration
relationship: negatively_regulates GO:0016477 ! cell migration

[Term]
id: GO:0030397
name: membrane disassembly
namespace: biological_process
def: "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy." [GOC:mah]
synonym: "membrane breakdown" EXACT []
synonym: "membrane catabolism" EXACT []
synonym: "membrane degradation" EXACT []
is_a: GO:0022411 ! cellular component disassembly
is_a: GO:0061024 ! membrane organization
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0016020 ! membrane
relationship: results_in_disassembly_of GO:0016020 ! membrane

[Term]
id: GO:0030421
name: defecation
namespace: biological_process
def: "The expulsion of feces from the rectum." [GOC:mah]
xref: Wikipedia:Defecation
is_a: GO:0007588 ! excretion
is_a: GO:0022600 ! digestive system process

[Term]
id: GO:0030432
name: peristalsis
namespace: biological_process
def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards." [ISBN:0198506732]
xref: Wikipedia:Peristalsis
is_a: GO:0014821 ! phasic smooth muscle contraction

[Term]
id: GO:0030473
name: nuclear migration along microtubule
namespace: biological_process
alt_id: GO:0000065
def: "The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins." [GOC:mah, GOC:sgd_curators]
synonym: "microtubule cytoskeleton-dependent nuclear positioning" EXACT []
synonym: "microtubule cytoskeleton-dependent nucleus positioning" EXACT []
synonym: "microtubule-dependent nuclear positioning" EXACT []
synonym: "microtubule-dependent nucleus positioning" EXACT []
synonym: "microtubule-mediated nuclear migration" EXACT []
synonym: "nuclear migration, microtubule-mediated" EXACT []
synonym: "nuclear movement, microtubule-mediated" BROAD []
synonym: "nucleus migration" BROAD []
synonym: "transport of nucleus by microtubules" EXACT []
synonym: "transport of nucleus, microtubule-mediated" EXACT []
is_a: GO:0007097 ! nuclear migration
is_a: GO:0072384 ! organelle transport along microtubule
intersection_of: GO:0007097 ! nuclear migration
intersection_of: results_in_transport_along GO:0015630 ! microtubule cytoskeleton
relationship: results_in_transport_along GO:0015630 ! microtubule cytoskeleton

[Term]
id: GO:0030485
name: smooth muscle contractile fiber
namespace: cellular_component
def: "The contractile fiber of smooth muscle cells." [GOC:mah]
is_a: GO:0043292 ! contractile fiber
intersection_of: GO:0043292 ! contractile fiber
intersection_of: part_of CL:0000192 ! smooth muscle cell
relationship: part_of CL:0000192 ! smooth muscle cell

[Term]
id: GO:0030539
name: male genitalia development
namespace: biological_process
def: "The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure." [GOC:ems, ISBN:0140512888]
synonym: "male genital development" EXACT []
is_a: GO:0048806 ! genitalia development
is_a: GO:0061458 ! reproductive system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000079 ! male reproductive system
relationship: part_of GO:0046661 ! male sex differentiation
relationship: results_in_development_of UBERON:0000079 ! male reproductive system

[Term]
id: GO:0030573
name: bile acid catabolic process
namespace: biological_process
alt_id: GO:0019613
def: "The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators]
synonym: "bile acid 7alpha-dehydroxylation pathway" NARROW []
synonym: "bile acid breakdown" EXACT []
synonym: "bile acid catabolism" EXACT []
synonym: "bile acid degradation" EXACT []
synonym: "cholate catabolic process" NARROW []
is_a: GO:0008206 ! bile acid metabolic process
is_a: GO:0072329 ! monocarboxylic acid catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:36235 ! bile acid anion
relationship: has_primary_input CHEBI:36235 ! bile acid anion

[Term]
id: GO:0030574
name: collagen catabolic process
namespace: biological_process
def: "The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells." [GOC:mah, ISBN:0815316194]
synonym: "collagen breakdown" EXACT []
synonym: "collagen catabolism" EXACT []
synonym: "collagen degradation" EXACT []
is_a: GO:0009056 ! catabolic process
is_a: GO:0032963 ! collagen metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input GO:0005581 ! collagen trimer
relationship: has_primary_input GO:0005581 ! collagen trimer

[Term]
id: GO:0030658
name: transport vesicle membrane
namespace: cellular_component
def: "The lipid bilayer surrounding a transport vesicle." [GOC:mah]
synonym: "constitutive secretory pathway transport vesicle membrane" EXACT []
synonym: "secretory vesicle membrane" BROAD []
is_a: GO:0030659 ! cytoplasmic vesicle membrane
is_a: GO:0098588 ! bounding membrane of organelle
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0030133 ! transport vesicle
relationship: bounding_layer_of GO:0030133 ! transport vesicle
relationship: part_of GO:0030133 ! transport vesicle

[Term]
id: GO:0030659
name: cytoplasmic vesicle membrane
namespace: cellular_component
def: "The lipid bilayer surrounding a cytoplasmic vesicle." [GOC:mah]
is_a: GO:0012506 ! vesicle membrane
intersection_of: GO:0016020 ! membrane
intersection_of: part_of GO:0031410 ! cytoplasmic vesicle
relationship: part_of GO:0031410 ! cytoplasmic vesicle

[Term]
id: GO:0030660
name: Golgi-associated vesicle membrane
namespace: cellular_component
def: "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus." [GOC:mah]
synonym: "Golgi vesicle membrane" RELATED []
is_a: GO:0030659 ! cytoplasmic vesicle membrane
is_a: GO:0098588 ! bounding membrane of organelle
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0005798 ! Golgi-associated vesicle
relationship: bounding_layer_of GO:0005798 ! Golgi-associated vesicle
relationship: part_of GO:0005798 ! Golgi-associated vesicle

[Term]
id: GO:0030667
name: secretory granule membrane
namespace: cellular_component
def: "The lipid bilayer surrounding a secretory granule." [GOC:mah]
synonym: "secretory vesicle membrane" BROAD []
is_a: GO:0030659 ! cytoplasmic vesicle membrane
is_a: GO:0098588 ! bounding membrane of organelle
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0030141 ! secretory granule
relationship: bounding_layer_of GO:0030141 ! secretory granule
relationship: part_of GO:0030141 ! secretory granule

[Term]
id: GO:0030705
name: cytoskeleton-dependent intracellular transport
namespace: biological_process
def: "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell." [GOC:mah]
subset: goslim_chembl
subset: goslim_drosophila
is_a: GO:0046907 ! intracellular transport
intersection_of: GO:0046907 ! intracellular transport
intersection_of: results_in_transport_along GO:0099513 ! polymeric cytoskeletal fiber
relationship: results_in_transport_along GO:0099513 ! polymeric cytoskeletal fiber

[Term]
id: GO:0030718
name: germ-line stem cell population maintenance
namespace: biological_process
def: "Any process by which an organism or tissue maintains a population of germ-line stem cells." [ISBN:0879694238]
is_a: GO:0019827 ! stem cell population maintenance
intersection_of: GO:0098727 ! maintenance of cell number
intersection_of: acts_on_population_of CL:0000014 ! germ line stem cell
relationship: acts_on_population_of CL:0000014 ! germ line stem cell

[Term]
id: GO:0030720
name: oocyte localization involved in germarium-derived egg chamber formation
namespace: biological_process
def: "Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber." [GOC:mtg_sensu, PMID:10449356]
synonym: "establishment and maintenance of oocyte localization in egg chamber" EXACT []
synonym: "establishment and maintenance of oocyte position during oogenesis" EXACT []
synonym: "oocyte localisation involved in germarium-derived egg chamber formation" EXACT [GOC:mah]
synonym: "oocyte localization during germarium-derived egg chamber formation" RELATED [GOC:dph, GOC:tb]
synonym: "oocyte localization during oogenesis" RELATED []
synonym: "oocyte positioning during oogenesis" NARROW []
synonym: "oogenesis, establishment and maintenance of oocyte localization" EXACT []
synonym: "oogenesis, oocyte localization" EXACT []
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0051674 ! localization of cell
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input CL:0000023 ! oocyte
relationship: has_primary_input CL:0000023 ! oocyte
relationship: in_taxon NCBITaxon:50557 {all_only="true"} ! Insecta
relationship: only_in_taxon NCBITaxon:50557 ! Insecta
relationship: part_of GO:0007293 ! germarium-derived egg chamber formation

[Term]
id: GO:0030855
name: epithelial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium." [GOC:ecd, PMID:11839751]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000066 ! epithelial cell
relationship: part_of GO:0060429 ! epithelium development
relationship: results_in_acquisition_of_features_of CL:0000066 ! epithelial cell

[Term]
id: GO:0030856
name: regulation of epithelial cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." [GOC:mah]
is_a: GO:0045595 ! regulation of cell differentiation
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030855 ! epithelial cell differentiation
relationship: regulates GO:0030855 ! epithelial cell differentiation

[Term]
id: GO:0030857
name: negative regulation of epithelial cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation." [GOC:mah]
synonym: "down regulation of epithelial cell differentiation" EXACT []
synonym: "down-regulation of epithelial cell differentiation" EXACT []
synonym: "downregulation of epithelial cell differentiation" EXACT []
synonym: "inhibition of epithelial cell differentiation" NARROW []
is_a: GO:0030856 ! regulation of epithelial cell differentiation
is_a: GO:0045596 ! negative regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030855 ! epithelial cell differentiation
relationship: negatively_regulates GO:0030855 ! epithelial cell differentiation

[Term]
id: GO:0030858
name: positive regulation of epithelial cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." [GOC:mah]
synonym: "activation of epithelial cell differentiation" NARROW []
synonym: "stimulation of epithelial cell differentiation" NARROW []
synonym: "up regulation of epithelial cell differentiation" EXACT []
synonym: "up-regulation of epithelial cell differentiation" EXACT []
synonym: "upregulation of epithelial cell differentiation" EXACT []
is_a: GO:0030856 ! regulation of epithelial cell differentiation
is_a: GO:0045597 ! positive regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030855 ! epithelial cell differentiation
relationship: positively_regulates GO:0030855 ! epithelial cell differentiation

[Term]
id: GO:0030901
name: midbrain development
namespace: biological_process
def: "The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=midbrain]
synonym: "mesencephalon development" EXACT []
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001891 ! midbrain
relationship: part_of GO:0007420 ! brain development
relationship: results_in_development_of UBERON:0001891 ! midbrain

[Term]
id: GO:0030902
name: hindbrain development
namespace: biological_process
def: "The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hindbrain]
synonym: "rhombencephalon development" EXACT []
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002028 ! hindbrain
relationship: part_of GO:0007420 ! brain development
relationship: results_in_development_of UBERON:0002028 ! hindbrain

[Term]
id: GO:0030903
name: notochord development
namespace: biological_process
def: "The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:dgh]
is_a: GO:0048568 ! embryonic organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002328 ! notochord
relationship: results_in_development_of UBERON:0002328 ! notochord

[Term]
id: GO:0030917
name: midbrain-hindbrain boundary development
namespace: biological_process
def: "The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages." [GOC:dgh]
synonym: "isthmic organizer development" EXACT []
synonym: "isthmomesencephalic boundary development" EXACT []
synonym: "isthmus development" EXACT []
synonym: "MHB development" EXACT []
synonym: "midbrain-hindbrain orgainizer development" EXACT []
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003052 ! midbrain-hindbrain boundary
relationship: part_of GO:0007420 ! brain development
relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning
relationship: results_in_development_of UBERON:0003052 ! midbrain-hindbrain boundary

[Term]
id: GO:0030936
name: transmembrane collagen trimer
namespace: cellular_component
def: "Any collagen trimer that passes through a lipid bilayer membrane." [ISBN:0721639976]
synonym: "MACIT" EXACT [ISBN:0198599587]
is_a: GO:0005581 ! collagen trimer
is_a: GO:0098797 ! plasma membrane protein complex
intersection_of: GO:0005581 ! collagen trimer
intersection_of: part_of GO:0005886 ! plasma membrane

[Term]
id: GO:0030951
name: establishment or maintenance of microtubule cytoskeleton polarity
namespace: biological_process
def: "Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures." [GOC:mah]
is_a: GO:0000226 ! microtubule cytoskeleton organization
is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity

[Term]
id: GO:0030952
name: establishment or maintenance of cytoskeleton polarity
namespace: biological_process
def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures." [GOC:mah]
synonym: "cytoskeleton polarization" RELATED []
is_a: GO:0007010 ! cytoskeleton organization
is_a: GO:0007163 ! establishment or maintenance of cell polarity

[Term]
id: GO:0030990
name: intraciliary transport particle
namespace: cellular_component
def: "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." [GOC:cilia, GOC:kmv, PMID:14570576, PMID:22118932, PMID:23945166]
comment: Note that we deem cilia and microtubule-based flagella to be equivalent.
subset: goslim_pir
synonym: "IFT complex" RELATED []
synonym: "intraflagellar transport complex" EXACT []
synonym: "intraflagellar transport particle" EXACT []
is_a: GO:0032991 ! protein-containing complex
relationship: capable_of_part_of GO:0035735 ! intraciliary transport involved in cilium assembly

[Term]
id: GO:0031012
name: extracellular matrix
namespace: cellular_component
alt_id: GO:0005578
def: "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." [GOC:BHF, GOC:mah, GOC:rph, NIF_Subcellular:nlx_subcell_20090513, PMID:21123617, PMID:28089324]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pir
subset: goslim_prokaryote
synonym: "matrisome" NARROW []
synonym: "proteinaceous extracellular matrix" EXACT []
xref: NIF_Subcellular:nlx_subcell_20090513
xref: Wikipedia:Extracellular_matrix
is_a: GO:0030312 ! external encapsulating structure
disjoint_from: GO:0032991 ! protein-containing complex
disjoint_from: GO:0043226 ! organelle

[Term]
id: GO:0031016
name: pancreas development
namespace: biological_process
def: "The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones." [GOC:cvs]
xref: Wikipedia:Pancreas
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001264 ! pancreas
relationship: results_in_development_of UBERON:0001264 ! pancreas
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23777" xsd:anyURI

[Term]
id: GO:0031017
name: exocrine pancreas development
namespace: biological_process
def: "The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells." [GOC:cvs]
is_a: GO:0048732 ! gland development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000017 ! exocrine pancreas
relationship: part_of GO:0031016 ! pancreas development
relationship: part_of GO:0035272 ! exocrine system development
relationship: part_of GO:0055123 ! digestive system development
relationship: results_in_development_of UBERON:0000017 ! exocrine pancreas

[Term]
id: GO:0031018
name: endocrine pancreas development
namespace: biological_process
def: "The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin." [GOC:cvs]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000016 ! endocrine pancreas
relationship: part_of GO:0031016 ! pancreas development
relationship: part_of GO:0035270 ! endocrine system development
relationship: results_in_development_of UBERON:0000016 ! endocrine pancreas

[Term]
id: GO:0031022
name: nuclear migration along microfilament
namespace: biological_process
def: "The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins." [GOC:mah]
synonym: "nuclear migration, microfilament-mediated" EXACT []
is_a: GO:0007097 ! nuclear migration
is_a: GO:0030048 ! actin filament-based movement
is_a: GO:0099515 ! actin filament-based transport
intersection_of: GO:0007097 ! nuclear migration
intersection_of: results_in_transport_along GO:0005884 ! actin filament

[Term]
id: GO:0031032
name: actomyosin structure organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments." [GOC:dph, GOC:jl, GOC:mah]
comment: Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins.
synonym: "actomyosin organization" EXACT []
synonym: "actomyosin structure organisation" EXACT []
synonym: "actomyosin structure organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0030036 ! actin cytoskeleton organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0042641 ! actomyosin
relationship: results_in_organization_of GO:0042641 ! actomyosin

[Term]
id: GO:0031045
name: dense core granule
namespace: cellular_component
def: "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted." [NIF_Subcellular:sao772007592, PMID:14690495]
synonym: "dense core vesicle" EXACT syngo_official_label [GOC:kmv]
xref: NIF_Subcellular:sao772007592
is_a: GO:0030141 ! secretory granule

[Term]
id: GO:0031076
name: embryonic camera-type eye development
namespace: biological_process
def: "The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure." [GOC:mah, GOC:mtg_sensu]
synonym: "embryonic eye development" EXACT []
is_a: GO:0043010 ! camera-type eye development
is_a: GO:0048568 ! embryonic organ development

[Term]
id: GO:0031090
name: organelle membrane
namespace: cellular_component
def: "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." [GOC:dos, GOC:mah]
synonym: "intracellular membrane" RELATED [NIF_Subcellular:sao830981606]
xref: NIF_Subcellular:sao830981606
is_a: GO:0016020 ! membrane
intersection_of: GO:0016020 ! membrane
intersection_of: part_of GO:0043227 ! membrane-bounded organelle
relationship: part_of GO:0043227 ! membrane-bounded organelle

[Term]
id: GO:0031109
name: microtubule polymerization or depolymerization
namespace: biological_process
def: "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah]
synonym: "microtubule dynamics" EXACT []
is_a: GO:0000226 ! microtubule cytoskeleton organization
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23195" xsd:anyURI

[Term]
id: GO:0031110
name: regulation of microtubule polymerization or depolymerization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah]
is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0031109 ! microtubule polymerization or depolymerization
relationship: regulates GO:0031109 ! microtubule polymerization or depolymerization

[Term]
id: GO:0031111
name: negative regulation of microtubule polymerization or depolymerization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah]
synonym: "down regulation of microtubule polymerization or depolymerization" EXACT []
synonym: "down-regulation of microtubule polymerization or depolymerization" EXACT []
synonym: "downregulation of microtubule polymerization or depolymerization" EXACT []
synonym: "inhibition of microtubule polymerization or depolymerization" NARROW []
is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization
is_a: GO:0051494 ! negative regulation of cytoskeleton organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0031109 ! microtubule polymerization or depolymerization
relationship: negatively_regulates GO:0031109 ! microtubule polymerization or depolymerization

[Term]
id: GO:0031112
name: positive regulation of microtubule polymerization or depolymerization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah]
synonym: "activation of microtubule polymerization or depolymerization" NARROW []
synonym: "stimulation of microtubule polymerization or depolymerization" NARROW []
synonym: "up regulation of microtubule polymerization or depolymerization" EXACT []
synonym: "up-regulation of microtubule polymerization or depolymerization" EXACT []
synonym: "upregulation of microtubule polymerization or depolymerization" EXACT []
is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization
is_a: GO:0051495 ! positive regulation of cytoskeleton organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0031109 ! microtubule polymerization or depolymerization
relationship: positively_regulates GO:0031109 ! microtubule polymerization or depolymerization

[Term]
id: GO:0031113
name: regulation of microtubule polymerization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of microtubule polymerization." [GOC:mah]
is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization
is_a: GO:0032271 ! regulation of protein polymerization
is_a: GO:1902903 ! regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0046785 ! microtubule polymerization
relationship: regulates GO:0046785 ! microtubule polymerization

[Term]
id: GO:0031114
name: regulation of microtubule depolymerization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of microtubule depolymerization." [GOC:mah]
synonym: "regulation of microtubule disassembly" EXACT []
is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization
is_a: GO:1901879 ! regulation of protein depolymerization
is_a: GO:1902903 ! regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007019 ! microtubule depolymerization
relationship: regulates GO:0007019 ! microtubule depolymerization

[Term]
id: GO:0031115
name: negative regulation of microtubule polymerization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." [GOC:mah]
synonym: "down regulation of microtubule polymerization" EXACT []
synonym: "down-regulation of microtubule polymerization" EXACT []
synonym: "downregulation of microtubule polymerization" EXACT []
synonym: "inhibition of microtubule polymerization" NARROW []
is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization
is_a: GO:0031113 ! regulation of microtubule polymerization
is_a: GO:0032272 ! negative regulation of protein polymerization
is_a: GO:1902904 ! negative regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0046785 ! microtubule polymerization
relationship: negatively_regulates GO:0046785 ! microtubule polymerization

[Term]
id: GO:0031116
name: positive regulation of microtubule polymerization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." [GOC:mah]
synonym: "activation of microtubule polymerization" NARROW []
synonym: "stimulation of microtubule polymerization" NARROW []
synonym: "up regulation of microtubule polymerization" EXACT []
synonym: "up-regulation of microtubule polymerization" EXACT []
synonym: "upregulation of microtubule polymerization" EXACT []
is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization
is_a: GO:0031113 ! regulation of microtubule polymerization
is_a: GO:0032273 ! positive regulation of protein polymerization
is_a: GO:1902905 ! positive regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0046785 ! microtubule polymerization
relationship: positively_regulates GO:0046785 ! microtubule polymerization

[Term]
id: GO:0031117
name: positive regulation of microtubule depolymerization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." [GOC:mah]
synonym: "activation of microtubule depolymerization" NARROW []
synonym: "microtubule destabilization" EXACT []
synonym: "positive regulation of microtubule catastrophe" NARROW [GOC:dph, GOC:tb]
synonym: "positive regulation of microtubule disassembly" EXACT []
synonym: "stimulation of microtubule depolymerization" NARROW []
synonym: "up regulation of microtubule depolymerization" EXACT []
synonym: "up-regulation of microtubule depolymerization" EXACT []
synonym: "upregulation of microtubule depolymerization" EXACT []
is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization
is_a: GO:0031114 ! regulation of microtubule depolymerization
is_a: GO:1901881 ! positive regulation of protein depolymerization
is_a: GO:1902905 ! positive regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007019 ! microtubule depolymerization
relationship: positively_regulates GO:0007019 ! microtubule depolymerization

[Term]
id: GO:0031122
name: cytoplasmic microtubule organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." [GOC:mah]
synonym: "cytoplasmic microtubule organisation" EXACT []
synonym: "cytoplasmic microtubule organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0000226 ! microtubule cytoskeleton organization
is_a: GO:0097435 ! supramolecular fiber organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005881 ! cytoplasmic microtubule
relationship: results_in_organization_of GO:0005881 ! cytoplasmic microtubule

[Term]
id: GO:0031128
name: developmental induction
namespace: biological_process
def: "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." [GOC:cjm, GOC:dph, GOC:mah, PMID:24503535]
is_a: GO:0032502 ! developmental process
intersection_of: GO:0032502 ! developmental process
intersection_of: has_part GO:0045168 ! cell-cell signaling involved in cell fate commitment
relationship: has_part GO:0045168 ! cell-cell signaling involved in cell fate commitment
property_value: RO:0002161 NCBITaxon:4895

[Term]
id: GO:0031175
name: neuron projection development
namespace: biological_process
def: "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:mah]
synonym: "neurite biosynthesis" NARROW []
synonym: "neurite development" NARROW [GOC:dph]
synonym: "neurite formation" NARROW []
synonym: "neurite growth" NARROW []
synonym: "neurite outgrowth" NARROW []
is_a: GO:0120036 ! plasma membrane bounded cell projection organization
intersection_of: GO:0120036 ! plasma membrane bounded cell projection organization
intersection_of: part_of GO:0048666 ! neuron development
relationship: part_of GO:0048666 ! neuron development

[Term]
id: GO:0031252
name: cell leading edge
namespace: cellular_component
def: "The area of a motile cell closest to the direction of movement." [GOC:pg]
subset: goslim_pir
synonym: "front of cell" EXACT []
synonym: "leading edge of cell" EXACT []
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of CL:0000000 ! cell

[Term]
id: GO:0031253
name: cell projection membrane
namespace: cellular_component
def: "The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection." [GOC:krc, GOC:mah]
synonym: "membrane extension" RELATED []
synonym: "membrane projection" RELATED []
is_a: GO:0098590 ! plasma membrane region
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0120025 ! plasma membrane bounded cell projection
relationship: bounding_layer_of GO:0120025 ! plasma membrane bounded cell projection
relationship: part_of GO:0120025 ! plasma membrane bounded cell projection

[Term]
id: GO:0031256
name: leading edge membrane
namespace: cellular_component
def: "The portion of the plasma membrane surrounding the leading edge of a motile cell." [GOC:mah]
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of GO:0005886 ! plasma membrane
relationship: part_of GO:0031252 ! cell leading edge

[Term]
id: GO:0031323
name: regulation of cellular metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "regulation of cellular metabolism" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0044237 ! cellular metabolic process
relationship: regulates GO:0044237 ! cellular metabolic process

[Term]
id: GO:0031324
name: negative regulation of cellular metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "down regulation of cellular metabolic process" EXACT []
synonym: "down-regulation of cellular metabolic process" EXACT []
synonym: "downregulation of cellular metabolic process" EXACT []
synonym: "inhibition of cellular metabolic process" NARROW []
synonym: "negative regulation of cellular metabolism" EXACT []
is_a: GO:0009892 ! negative regulation of metabolic process
is_a: GO:0031323 ! regulation of cellular metabolic process
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0044237 ! cellular metabolic process
relationship: negatively_regulates GO:0044237 ! cellular metabolic process

[Term]
id: GO:0031325
name: positive regulation of cellular metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "activation of cellular metabolic process" NARROW []
synonym: "positive regulation of cellular metabolism" EXACT []
synonym: "stimulation of cellular metabolic process" NARROW []
synonym: "up regulation of cellular metabolic process" EXACT []
synonym: "up-regulation of cellular metabolic process" EXACT []
synonym: "upregulation of cellular metabolic process" EXACT []
is_a: GO:0009893 ! positive regulation of metabolic process
is_a: GO:0031323 ! regulation of cellular metabolic process
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0044237 ! cellular metabolic process
relationship: positively_regulates GO:0044237 ! cellular metabolic process

[Term]
id: GO:0031326
name: regulation of cellular biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah]
synonym: "regulation of cellular anabolism" EXACT []
synonym: "regulation of cellular biosynthesis" EXACT []
synonym: "regulation of cellular formation" EXACT []
synonym: "regulation of cellular synthesis" EXACT []
is_a: GO:0009889 ! regulation of biosynthetic process
is_a: GO:0031323 ! regulation of cellular metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0044249 ! cellular biosynthetic process
relationship: regulates GO:0044249 ! cellular biosynthetic process

[Term]
id: GO:0031327
name: negative regulation of cellular biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah]
synonym: "down regulation of cellular biosynthetic process" EXACT []
synonym: "down-regulation of cellular biosynthetic process" EXACT []
synonym: "downregulation of cellular biosynthetic process" EXACT []
synonym: "inhibition of cellular biosynthetic process" NARROW []
synonym: "negative regulation of cellular anabolism" EXACT []
synonym: "negative regulation of cellular biosynthesis" EXACT []
synonym: "negative regulation of cellular formation" EXACT []
synonym: "negative regulation of cellular synthesis" EXACT []
is_a: GO:0009890 ! negative regulation of biosynthetic process
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0031326 ! regulation of cellular biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0044249 ! cellular biosynthetic process
relationship: negatively_regulates GO:0044249 ! cellular biosynthetic process

[Term]
id: GO:0031328
name: positive regulation of cellular biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah]
synonym: "activation of cellular biosynthetic process" NARROW []
synonym: "positive regulation of cellular anabolism" EXACT []
synonym: "positive regulation of cellular biosynthesis" EXACT []
synonym: "positive regulation of cellular formation" EXACT []
synonym: "positive regulation of cellular synthesis" EXACT []
synonym: "stimulation of cellular biosynthetic process" NARROW []
synonym: "up regulation of cellular biosynthetic process" EXACT []
synonym: "up-regulation of cellular biosynthetic process" EXACT []
synonym: "upregulation of cellular biosynthetic process" EXACT []
is_a: GO:0009891 ! positive regulation of biosynthetic process
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0031326 ! regulation of cellular biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0044249 ! cellular biosynthetic process
relationship: positively_regulates GO:0044249 ! cellular biosynthetic process

[Term]
id: GO:0031329
name: regulation of cellular catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah]
synonym: "regulation of cellular breakdown" EXACT []
synonym: "regulation of cellular catabolism" EXACT []
synonym: "regulation of cellular degradation" EXACT []
is_a: GO:0009894 ! regulation of catabolic process
is_a: GO:0031323 ! regulation of cellular metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0044248 ! cellular catabolic process
relationship: regulates GO:0044248 ! cellular catabolic process

[Term]
id: GO:0031330
name: negative regulation of cellular catabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah]
synonym: "down regulation of cellular catabolic process" EXACT []
synonym: "down-regulation of cellular catabolic process" EXACT []
synonym: "downregulation of cellular catabolic process" EXACT []
synonym: "inhibition of cellular catabolic process" NARROW []
synonym: "negative regulation of cellular breakdown" EXACT []
synonym: "negative regulation of cellular catabolism" EXACT []
synonym: "negative regulation of cellular degradation" EXACT []
is_a: GO:0009895 ! negative regulation of catabolic process
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0031329 ! regulation of cellular catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0044248 ! cellular catabolic process
relationship: negatively_regulates GO:0044248 ! cellular catabolic process

[Term]
id: GO:0031331
name: positive regulation of cellular catabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah]
synonym: "activation of cellular catabolic process" NARROW []
synonym: "positive regulation of cellular breakdown" EXACT []
synonym: "positive regulation of cellular catabolism" EXACT []
synonym: "positive regulation of cellular degradation" EXACT []
synonym: "stimulation of cellular catabolic process" NARROW []
synonym: "up regulation of cellular catabolic process" EXACT []
synonym: "up-regulation of cellular catabolic process" EXACT []
synonym: "upregulation of cellular catabolic process" EXACT []
is_a: GO:0009896 ! positive regulation of catabolic process
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0031329 ! regulation of cellular catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0044248 ! cellular catabolic process
relationship: positively_regulates GO:0044248 ! cellular catabolic process

[Term]
id: GO:0031333
name: negative regulation of protein-containing complex assembly
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." [GOC:mah]
synonym: "down regulation of protein complex assembly" EXACT []
synonym: "down-regulation of protein complex assembly" EXACT []
synonym: "downregulation of protein complex assembly" EXACT []
synonym: "inhibition of protein complex assembly" NARROW []
synonym: "negative regulation of protein complex assembly" RELATED []
is_a: GO:0043254 ! regulation of protein-containing complex assembly
is_a: GO:0051129 ! negative regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0065003 ! protein-containing complex assembly
relationship: negatively_regulates GO:0065003 ! protein-containing complex assembly

[Term]
id: GO:0031334
name: positive regulation of protein-containing complex assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein complex assembly." [GOC:mah]
synonym: "activation of protein complex assembly" NARROW []
synonym: "positive regulation of protein complex assembly" RELATED []
synonym: "stimulation of protein complex assembly" NARROW []
synonym: "up regulation of protein complex assembly" EXACT []
synonym: "up-regulation of protein complex assembly" EXACT []
synonym: "upregulation of protein complex assembly" EXACT []
is_a: GO:0043254 ! regulation of protein-containing complex assembly
is_a: GO:0044089 ! positive regulation of cellular component biogenesis
is_a: GO:0051130 ! positive regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0065003 ! protein-containing complex assembly
relationship: positively_regulates GO:0065003 ! protein-containing complex assembly

[Term]
id: GO:0031338
name: regulation of vesicle fusion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vesicle fusion." [GOC:mah]
is_a: GO:0033043 ! regulation of organelle organization
is_a: GO:0060627 ! regulation of vesicle-mediated transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006906 ! vesicle fusion
relationship: regulates GO:0006906 ! vesicle fusion

[Term]
id: GO:0031339
name: negative regulation of vesicle fusion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." [GOC:mah]
synonym: "down regulation of vesicle fusion" EXACT []
synonym: "down-regulation of vesicle fusion" EXACT []
synonym: "downregulation of vesicle fusion" EXACT []
synonym: "inhibition of vesicle fusion" NARROW []
is_a: GO:0010639 ! negative regulation of organelle organization
is_a: GO:0031338 ! regulation of vesicle fusion
is_a: GO:0051051 ! negative regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006906 ! vesicle fusion
relationship: negatively_regulates GO:0006906 ! vesicle fusion

[Term]
id: GO:0031340
name: positive regulation of vesicle fusion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion." [GOC:mah]
synonym: "activation of vesicle fusion" NARROW []
synonym: "stimulation of vesicle fusion" NARROW []
synonym: "up regulation of vesicle fusion" EXACT []
synonym: "up-regulation of vesicle fusion" EXACT []
synonym: "upregulation of vesicle fusion" EXACT []
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:0031338 ! regulation of vesicle fusion
is_a: GO:0051050 ! positive regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006906 ! vesicle fusion
relationship: positively_regulates GO:0006906 ! vesicle fusion

[Term]
id: GO:0031344
name: regulation of cell projection organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah]
synonym: "regulation of cell projection organisation" EXACT []
synonym: "regulation of cell projection organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030030 ! cell projection organization
relationship: regulates GO:0030030 ! cell projection organization

[Term]
id: GO:0031345
name: negative regulation of cell projection organization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah]
synonym: "down regulation of cell projection organization" EXACT [GOC:mah]
synonym: "down-regulation of cell projection organization" EXACT []
synonym: "downregulation of cell projection organization" EXACT []
synonym: "inhibition of cell projection organization" NARROW []
synonym: "negative regulation of cell projection organisation" EXACT []
synonym: "negative regulation of cell projection organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0031344 ! regulation of cell projection organization
is_a: GO:0051129 ! negative regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030030 ! cell projection organization
relationship: negatively_regulates GO:0030030 ! cell projection organization

[Term]
id: GO:0031346
name: positive regulation of cell projection organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah]
synonym: "activation of cell projection organization" NARROW []
synonym: "positive regulation of cell projection organisation" EXACT []
synonym: "positive regulation of cell projection organization and biogenesis" RELATED [GOC:mah]
synonym: "stimulation of cell projection organization" NARROW []
synonym: "up regulation of cell projection organization" EXACT []
synonym: "up-regulation of cell projection organization" EXACT []
synonym: "upregulation of cell projection organization" EXACT []
is_a: GO:0031344 ! regulation of cell projection organization
is_a: GO:0051130 ! positive regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030030 ! cell projection organization
relationship: positively_regulates GO:0030030 ! cell projection organization

[Term]
id: GO:0031347
name: regulation of defense response
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a defense response." [GOC:mah]
is_a: GO:0080134 ! regulation of response to stress
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006952 ! defense response
relationship: regulates GO:0006952 ! defense response

[Term]
id: GO:0031348
name: negative regulation of defense response
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." [GOC:mah]
synonym: "down regulation of defense response" EXACT []
synonym: "down-regulation of defense response" EXACT []
synonym: "downregulation of defense response" EXACT []
synonym: "inhibition of defense response" NARROW []
is_a: GO:0031347 ! regulation of defense response
is_a: GO:0048585 ! negative regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006952 ! defense response
relationship: negatively_regulates GO:0006952 ! defense response

[Term]
id: GO:0031349
name: positive regulation of defense response
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of a defense response." [GOC:mah]
synonym: "activation of defense response" NARROW []
synonym: "stimulation of defense response" NARROW []
synonym: "up regulation of defense response" EXACT []
synonym: "up-regulation of defense response" EXACT []
synonym: "upregulation of defense response" EXACT []
is_a: GO:0031347 ! regulation of defense response
is_a: GO:0048584 ! positive regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006952 ! defense response
relationship: positively_regulates GO:0006952 ! defense response

[Term]
id: GO:0031410
name: cytoplasmic vesicle
namespace: cellular_component
alt_id: GO:0016023
def: "A vesicle found in the cytoplasm of a cell." [GOC:ai, GOC:mah, GOC:vesicles]
subset: goslim_agr
subset: goslim_candida
subset: goslim_chembl
subset: goslim_generic
subset: goslim_mouse
subset: goslim_yeast
synonym: "cytoplasmic membrane bounded vesicle" RELATED []
synonym: "cytoplasmic membrane-enclosed vesicle" RELATED []
synonym: "cytoplasmic, membrane-bounded vesicle" RELATED []
xref: NIF_Subcellular:sao180601769
is_a: GO:0097708 ! intracellular vesicle
intersection_of: GO:0031982 ! vesicle
intersection_of: part_of GO:0005737 ! cytoplasm
relationship: part_of GO:0005737 ! cytoplasm

[Term]
id: GO:0031503
name: protein-containing complex localization
namespace: biological_process
alt_id: GO:0034629
def: "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location." [GOC:mah]
synonym: "cellular protein complex localisation" RELATED [GOC:mah]
synonym: "cellular protein complex localization" RELATED []
synonym: "cellular protein-containing complex localization" RELATED []
synonym: "establishment and maintenance of cellular protein complex localization" RELATED []
synonym: "establishment and maintenance of protein complex localization" EXACT []
synonym: "protein complex localisation" EXACT [GOC:mah]
synonym: "protein complex localization" RELATED []
is_a: GO:0051179 ! localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0032991 ! protein-containing complex
relationship: has_primary_input GO:0032991 ! protein-containing complex
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI

[Term]
id: GO:0031514
name: motile cilium
namespace: cellular_component
alt_id: GO:0009434
alt_id: GO:0031512
def: "A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell." [GOC:cilia, GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998, PMID:22118931]
synonym: "microtubule-based flagellum" RELATED []
synonym: "motile cilia" EXACT []
synonym: "motile primary cilia" RELATED []
synonym: "motile primary cilium" RELATED []
synonym: "motile secondary cilium" RELATED []
synonym: "nodal cilium" RELATED []
is_a: GO:0005929 ! cilium
intersection_of: GO:0005929 ! cilium
intersection_of: capable_of GO:0003341 ! cilium movement
relationship: capable_of GO:0003341 ! cilium movement

[Term]
id: GO:0031594
name: neuromuscular junction
namespace: cellular_component
def: "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." [GOC:nln]
comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT.
synonym: "motor endplate" RELATED [NIF_Subcellular:nlx_subcell_20090512]
synonym: "NMJ" RELATED [GOC:ha]
xref: NIF_Subcellular:sao1124888485
xref: Wikipedia:Neuromuscular_junction
is_a: GO:0045202 ! synapse
intersection_of: GO:0045202 ! synapse
intersection_of: overlaps CL:0000100 ! motor neuron
intersection_of: overlaps CL:0000187 ! muscle cell
relationship: overlaps CL:0000100 ! motor neuron
relationship: overlaps CL:0000187 ! muscle cell

[Term]
id: GO:0031644
name: regulation of nervous system process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system." [GOC:dph, GOC:mah, GOC:tb]
synonym: "regulation of neurological process" EXACT [GOC:dph, GOC:tb]
synonym: "regulation of neurological system process" EXACT []
synonym: "regulation of neurophysiological process" EXACT []
is_a: GO:0044057 ! regulation of system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0050877 ! nervous system process
relationship: regulates GO:0050877 ! nervous system process

[Term]
id: GO:0031645
name: negative regulation of nervous system process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb]
synonym: "down regulation of neurological process" EXACT []
synonym: "down-regulation of neurological process" EXACT []
synonym: "downregulation of neurological process" EXACT []
synonym: "inhibition of neurological process" NARROW []
synonym: "negative regulation of neurological process" EXACT [GOC:dph, GOC:tb]
synonym: "negative regulation of neurological system process" EXACT []
synonym: "negative regulation of neurophysiological process" EXACT []
is_a: GO:0031644 ! regulation of nervous system process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0050877 ! nervous system process
relationship: negatively_regulates GO:0050877 ! nervous system process

[Term]
id: GO:0031646
name: positive regulation of nervous system process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb]
synonym: "activation of neurological process" NARROW []
synonym: "positive regulation of neurological process" EXACT [GOC:dph, GOC:tb]
synonym: "positive regulation of neurological system process" EXACT []
synonym: "positive regulation of neurophysiological process" EXACT []
synonym: "stimulation of neurological process" NARROW []
synonym: "up regulation of neurological process" EXACT []
synonym: "up-regulation of neurological process" EXACT []
synonym: "upregulation of neurological process" EXACT []
is_a: GO:0031644 ! regulation of nervous system process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0050877 ! nervous system process
relationship: positively_regulates GO:0050877 ! nervous system process

[Term]
id: GO:0031965
name: nuclear membrane
namespace: cellular_component
def: "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." [GOC:mah, GOC:pz]
xref: NIF_Subcellular:sao1687101204
is_a: GO:0031090 ! organelle membrane
intersection_of: GO:0016020 ! membrane
intersection_of: part_of GO:0005634 ! nucleus
relationship: part_of GO:0005635 ! nuclear envelope

[Term]
id: GO:0031967
name: organelle envelope
namespace: cellular_component
def: "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." [GOC:mah, GOC:pz]
subset: goslim_mouse
is_a: GO:0031975 ! envelope
relationship: part_of GO:0043227 ! membrane-bounded organelle
relationship: part_of GO:0043229 ! intracellular organelle

[Term]
id: GO:0031968
name: organelle outer membrane
namespace: cellular_component
def: "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope." [GOC:mah]
is_a: GO:0019867 ! outer membrane
is_a: GO:0098588 ! bounding membrane of organelle
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0043226 ! organelle
intersection_of: part_of GO:0031967 ! organelle envelope
relationship: part_of GO:0031967 ! organelle envelope

[Term]
id: GO:0031974
name: membrane-enclosed lumen
namespace: cellular_component
def: "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." [GOC:add, GOC:mah]
is_a: GO:0110165 ! cellular anatomical entity
disjoint_from: GO:0045202 ! synapse

[Term]
id: GO:0031975
name: envelope
namespace: cellular_component
def: "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers." [GOC:mah, GOC:pz]
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of CL:0000000 ! cell

[Term]
id: GO:0031981
name: nuclear lumen
namespace: cellular_component
def: "The volume enclosed by the nuclear inner membrane." [GOC:mah, GOC:pz]
is_a: GO:0070013 ! intracellular organelle lumen
relationship: part_of GO:0005634 ! nucleus

[Term]
id: GO:0031982
name: vesicle
namespace: cellular_component
alt_id: GO:0031988
def: "Any small, fluid-filled, spherical organelle enclosed by membrane." [GOC:mah, GOC:pz, GOC:vesicles]
subset: goslim_pir
synonym: "membrane-bounded vesicle" RELATED []
synonym: "membrane-enclosed vesicle" RELATED []
xref: NIF_Subcellular:sao221389602
xref: Wikipedia:Vesicle_(biology)
is_a: GO:0043227 ! membrane-bounded organelle

[Term]
id: GO:0031987
name: locomotion involved in locomotory behavior
namespace: biological_process
def: "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:mah]
synonym: "locomotion during locomotory behaviour" EXACT []
is_a: GO:0040011 ! locomotion
intersection_of: GO:0040011 ! locomotion
intersection_of: part_of GO:0007626 ! locomotory behavior
relationship: part_of GO:0007626 ! locomotory behavior

[Term]
id: GO:0032024
name: positive regulation of insulin secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin." [GOC:mah]
synonym: "activation of insulin secretion" NARROW []
synonym: "stimulation of insulin secretion" NARROW []
synonym: "up regulation of insulin secretion" EXACT []
synonym: "up-regulation of insulin secretion" EXACT []
synonym: "upregulation of insulin secretion" EXACT []
is_a: GO:0050714 ! positive regulation of protein secretion
is_a: GO:0050796 ! regulation of insulin secretion
is_a: GO:0090277 ! positive regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030073 ! insulin secretion
relationship: positively_regulates GO:0030073 ! insulin secretion

[Term]
id: GO:0032057
name: negative regulation of translational initiation in response to stress
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah]
synonym: "down regulation of translation initiation in response to stress" EXACT []
synonym: "down-regulation of translation initiation in response to stress" EXACT []
synonym: "downregulation of translation initiation in response to stress" EXACT []
synonym: "inhibition of translation initiation in response to stress" NARROW []
is_a: GO:0045947 ! negative regulation of translational initiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006413 ! translational initiation
intersection_of: part_of GO:0006950 ! response to stress
relationship: part_of GO:0006950 ! response to stress

[Term]
id: GO:0032058
name: positive regulation of translational initiation in response to stress
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah]
synonym: "activation of translation initiation in response to stress" NARROW []
synonym: "stimulation of translation initiation in response to stress" NARROW []
synonym: "up regulation of translation initiation in response to stress" EXACT []
synonym: "up-regulation of translation initiation in response to stress" EXACT []
synonym: "upregulation of translation initiation in response to stress" EXACT []
is_a: GO:0045948 ! positive regulation of translational initiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: part_of GO:0006950 ! response to stress
intersection_of: positively_regulates GO:0006413 ! translational initiation
relationship: part_of GO:0006950 ! response to stress

[Term]
id: GO:0032059
name: bleb
namespace: cellular_component
def: "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)]
subset: goslim_pir
synonym: "plasma membrane bleb" EXACT [GOC:pr]
xref: Wikipedia:Bleb_(cell_biology)
is_a: GO:0120025 ! plasma membrane bounded cell projection

[Term]
id: GO:0032060
name: bleb assembly
namespace: biological_process
def: "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mah, GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)]
synonym: "blebbing" BROAD [GOC:pr]
synonym: "cell blebbing" EXACT []
synonym: "membrane blebbing" BROAD [GOC:pr]
synonym: "plasma membrane bleb assembly" EXACT [GOC:pr]
synonym: "plasma membrane blebbing" EXACT [GOC:pr]
is_a: GO:0120031 ! plasma membrane bounded cell projection assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0032059 ! bleb
relationship: results_in_assembly_of GO:0032059 ! bleb

[Term]
id: GO:0032069
name: regulation of nuclease activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "nuclease regulator activity" RELATED []
is_a: GO:0051336 ! regulation of hydrolase activity
is_a: GO:0060255 ! regulation of macromolecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0004518 ! nuclease activity
relationship: regulates GO:0004518 ! nuclease activity

[Term]
id: GO:0032070
name: regulation of deoxyribonuclease activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "deoxyribonuclease regulator" RELATED []
synonym: "DNase regulator" RELATED []
is_a: GO:0032069 ! regulation of nuclease activity
is_a: GO:0051052 ! regulation of DNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0004536 ! DNA nuclease activity
relationship: regulates GO:0004536 ! DNA nuclease activity

[Term]
id: GO:0032074
name: negative regulation of nuclease activity
namespace: biological_process
def: "Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "down regulation of nuclease activity" EXACT []
synonym: "down-regulation of nuclease activity" EXACT []
synonym: "downregulation of nuclease activity" EXACT []
synonym: "inhibition of nuclease activity" NARROW []
synonym: "nuclease inhibitor" RELATED []
is_a: GO:0032069 ! regulation of nuclease activity
is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process
is_a: GO:0051346 ! negative regulation of hydrolase activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0004518 ! nuclease activity
relationship: negatively_regulates GO:0004518 ! nuclease activity

[Term]
id: GO:0032075
name: positive regulation of nuclease activity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "activation of nuclease activity" NARROW []
synonym: "nuclease activator" RELATED []
synonym: "stimulation of nuclease activity" NARROW []
synonym: "up regulation of nuclease activity" EXACT []
synonym: "up-regulation of nuclease activity" EXACT []
synonym: "upregulation of nuclease activity" EXACT []
is_a: GO:0032069 ! regulation of nuclease activity
is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process
is_a: GO:0051345 ! positive regulation of hydrolase activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0004518 ! nuclease activity
relationship: positively_regulates GO:0004518 ! nuclease activity

[Term]
id: GO:0032076
name: negative regulation of deoxyribonuclease activity
namespace: biological_process
def: "Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "deoxyribonuclease inhibitor" RELATED []
synonym: "DNase inhibitor" RELATED []
synonym: "down regulation of deoxyribonuclease activity" EXACT []
synonym: "down-regulation of deoxyribonuclease activity" EXACT []
synonym: "downregulation of deoxyribonuclease activity" EXACT []
synonym: "inhibition of deoxyribonuclease activity" NARROW []
is_a: GO:0032070 ! regulation of deoxyribonuclease activity
is_a: GO:0032074 ! negative regulation of nuclease activity
is_a: GO:0051053 ! negative regulation of DNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0004536 ! DNA nuclease activity
relationship: negatively_regulates GO:0004536 ! DNA nuclease activity

[Term]
id: GO:0032077
name: positive regulation of deoxyribonuclease activity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "activation of deoxyribonuclease activity" NARROW []
synonym: "deoxyribonuclease activator" RELATED []
synonym: "DNase activator" RELATED []
synonym: "stimulation of deoxyribonuclease activity" NARROW []
synonym: "up regulation of deoxyribonuclease activity" EXACT []
synonym: "up-regulation of deoxyribonuclease activity" EXACT []
synonym: "upregulation of deoxyribonuclease activity" EXACT []
is_a: GO:0032070 ! regulation of deoxyribonuclease activity
is_a: GO:0032075 ! positive regulation of nuclease activity
is_a: GO:0051054 ! positive regulation of DNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0004536 ! DNA nuclease activity
relationship: positively_regulates GO:0004536 ! DNA nuclease activity

[Term]
id: GO:0032101
name: regulation of response to external stimulus
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a response to an external stimulus." [GOC:mah]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009605 ! response to external stimulus
relationship: regulates GO:0009605 ! response to external stimulus

[Term]
id: GO:0032102
name: negative regulation of response to external stimulus
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." [GOC:mah]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "down regulation of response to external stimulus" EXACT []
synonym: "down-regulation of response to external stimulus" EXACT []
synonym: "downregulation of response to external stimulus" EXACT []
synonym: "inhibition of response to external stimulus" NARROW []
is_a: GO:0032101 ! regulation of response to external stimulus
is_a: GO:0048585 ! negative regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009605 ! response to external stimulus
relationship: negatively_regulates GO:0009605 ! response to external stimulus

[Term]
id: GO:0032103
name: positive regulation of response to external stimulus
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of a response to an external stimulus." [GOC:mah]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "activation of response to external stimulus" NARROW []
synonym: "stimulation of response to external stimulus" NARROW []
synonym: "up regulation of response to external stimulus" EXACT []
synonym: "up-regulation of response to external stimulus" EXACT []
synonym: "upregulation of response to external stimulus" EXACT []
is_a: GO:0032101 ! regulation of response to external stimulus
is_a: GO:0048584 ! positive regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009605 ! response to external stimulus
relationship: positively_regulates GO:0009605 ! response to external stimulus

[Term]
id: GO:0032127
name: dense core granule membrane
namespace: cellular_component
def: "The lipid bilayer surrounding a dense core granule." [GOC:mah]
synonym: "dense core vesicle membrane" EXACT [GOC:kmv]
is_a: GO:0030667 ! secretory granule membrane
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0031045 ! dense core granule
relationship: bounding_layer_of GO:0031045 ! dense core granule
relationship: part_of GO:0031045 ! dense core granule

[Term]
id: GO:0032222
name: regulation of synaptic transmission, cholinergic
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah]
is_a: GO:0050804 ! modulation of chemical synaptic transmission
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007271 ! synaptic transmission, cholinergic
relationship: regulates GO:0007271 ! synaptic transmission, cholinergic

[Term]
id: GO:0032223
name: negative regulation of synaptic transmission, cholinergic
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah]
synonym: "down regulation of synaptic transmission, cholinergic" EXACT []
synonym: "down-regulation of synaptic transmission, cholinergic" EXACT []
synonym: "downregulation of synaptic transmission, cholinergic" EXACT []
synonym: "inhibition of synaptic transmission, cholinergic" NARROW []
is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic
is_a: GO:0050805 ! negative regulation of synaptic transmission
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007271 ! synaptic transmission, cholinergic
relationship: negatively_regulates GO:0007271 ! synaptic transmission, cholinergic

[Term]
id: GO:0032224
name: positive regulation of synaptic transmission, cholinergic
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah]
synonym: "activation of synaptic transmission, cholinergic" NARROW []
synonym: "stimulation of synaptic transmission, cholinergic" NARROW []
synonym: "up regulation of synaptic transmission, cholinergic" EXACT []
synonym: "up-regulation of synaptic transmission, cholinergic" EXACT []
synonym: "upregulation of synaptic transmission, cholinergic" EXACT []
is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic
is_a: GO:0050806 ! positive regulation of synaptic transmission
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007271 ! synaptic transmission, cholinergic
relationship: positively_regulates GO:0007271 ! synaptic transmission, cholinergic

[Term]
id: GO:0032231
name: regulation of actin filament bundle assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah]
synonym: "regulation of actin cable assembly" EXACT [GOC:dph, GOC:tb]
synonym: "regulation of actin filament bundle formation" RELATED [GOC:dph]
is_a: GO:0044087 ! regulation of cellular component biogenesis
is_a: GO:0110053 ! regulation of actin filament organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051017 ! actin filament bundle assembly
relationship: regulates GO:0051017 ! actin filament bundle assembly

[Term]
id: GO:0032232
name: negative regulation of actin filament bundle assembly
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah]
synonym: "down regulation of actin filament bundle formation" EXACT []
synonym: "down-regulation of actin filament bundle formation" EXACT []
synonym: "downregulation of actin filament bundle formation" EXACT []
synonym: "inhibition of actin filament bundle formation" NARROW []
is_a: GO:0032231 ! regulation of actin filament bundle assembly
is_a: GO:0051494 ! negative regulation of cytoskeleton organization
is_a: GO:1902904 ! negative regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051017 ! actin filament bundle assembly
relationship: negatively_regulates GO:0051017 ! actin filament bundle assembly

[Term]
id: GO:0032233
name: positive regulation of actin filament bundle assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah]
synonym: "activation of actin filament bundle formation" NARROW []
synonym: "stimulation of actin filament bundle formation" NARROW []
synonym: "up regulation of actin filament bundle formation" EXACT []
synonym: "up-regulation of actin filament bundle formation" EXACT []
synonym: "upregulation of actin filament bundle formation" EXACT []
is_a: GO:0032231 ! regulation of actin filament bundle assembly
is_a: GO:0044089 ! positive regulation of cellular component biogenesis
is_a: GO:0051495 ! positive regulation of cytoskeleton organization
is_a: GO:1902905 ! positive regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051017 ! actin filament bundle assembly
relationship: positively_regulates GO:0051017 ! actin filament bundle assembly

[Term]
id: GO:0032239
name: regulation of nucleobase-containing compound transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb]
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0015931 ! nucleobase-containing compound transport
relationship: regulates GO:0015931 ! nucleobase-containing compound transport

[Term]
id: GO:0032240
name: negative regulation of nucleobase-containing compound transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT []
synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT []
synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT []
synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW []
synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb]
is_a: GO:0032239 ! regulation of nucleobase-containing compound transport
is_a: GO:0051051 ! negative regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0015931 ! nucleobase-containing compound transport
relationship: negatively_regulates GO:0015931 ! nucleobase-containing compound transport

[Term]
id: GO:0032241
name: positive regulation of nucleobase-containing compound transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
synonym: "activation of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW []
synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb]
synonym: "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW []
synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT []
synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT []
synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT []
is_a: GO:0032239 ! regulation of nucleobase-containing compound transport
is_a: GO:0051050 ! positive regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0015931 ! nucleobase-containing compound transport
relationship: positively_regulates GO:0015931 ! nucleobase-containing compound transport

[Term]
id: GO:0032252
name: secretory granule localization
namespace: biological_process
def: "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah]
synonym: "secretory granule clustering" RELATED []
synonym: "secretory granule localisation" EXACT [GOC:mah]
is_a: GO:0051648 ! vesicle localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0030141 ! secretory granule
relationship: has_primary_input GO:0030141 ! secretory granule

[Term]
id: GO:0032253
name: dense core granule localization
namespace: biological_process
def: "Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah]
synonym: "dense core granule clustering" RELATED []
synonym: "dense core granule localisation" EXACT [GOC:mah]
synonym: "dense core vesicle localization" EXACT [GOC:kmv]
is_a: GO:0032252 ! secretory granule localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0031045 ! dense core granule
relationship: has_primary_input GO:0031045 ! dense core granule

[Term]
id: GO:0032271
name: regulation of protein polymerization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." [GOC:mah]
synonym: "regulation of protein polymerisation" EXACT []
is_a: GO:0043254 ! regulation of protein-containing complex assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051258 ! protein polymerization
relationship: regulates GO:0051258 ! protein polymerization

[Term]
id: GO:0032272
name: negative regulation of protein polymerization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." [GOC:mah]
synonym: "down regulation of protein polymerization" EXACT []
synonym: "down-regulation of protein polymerization" EXACT []
synonym: "downregulation of protein polymerization" EXACT []
synonym: "inhibition of protein polymerization" NARROW []
is_a: GO:0031333 ! negative regulation of protein-containing complex assembly
is_a: GO:0032271 ! regulation of protein polymerization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051258 ! protein polymerization
relationship: negatively_regulates GO:0051258 ! protein polymerization

[Term]
id: GO:0032273
name: positive regulation of protein polymerization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." [GOC:mah]
synonym: "activation of protein polymerization" NARROW []
synonym: "stimulation of protein polymerization" NARROW []
synonym: "up regulation of protein polymerization" EXACT []
synonym: "up-regulation of protein polymerization" EXACT []
synonym: "upregulation of protein polymerization" EXACT []
is_a: GO:0031334 ! positive regulation of protein-containing complex assembly
is_a: GO:0032271 ! regulation of protein polymerization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051258 ! protein polymerization
relationship: positively_regulates GO:0051258 ! protein polymerization

[Term]
id: GO:0032330
name: regulation of chondrocyte differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of chondrocyte differentiation." [GOC:mah]
is_a: GO:0045595 ! regulation of cell differentiation
is_a: GO:0061035 ! regulation of cartilage development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002062 ! chondrocyte differentiation
relationship: regulates GO:0002062 ! chondrocyte differentiation

[Term]
id: GO:0032331
name: negative regulation of chondrocyte differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation." [GOC:mah]
synonym: "down regulation of chondrocyte differentiation" EXACT []
synonym: "down-regulation of chondrocyte differentiation" EXACT []
synonym: "downregulation of chondrocyte differentiation" EXACT []
synonym: "inhibition of chondrocyte differentiation" NARROW []
is_a: GO:0032330 ! regulation of chondrocyte differentiation
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0061037 ! negative regulation of cartilage development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002062 ! chondrocyte differentiation
relationship: negatively_regulates GO:0002062 ! chondrocyte differentiation

[Term]
id: GO:0032332
name: positive regulation of chondrocyte differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation." [GOC:mah]
synonym: "activation of chondrocyte differentiation" NARROW []
synonym: "stimulation of chondrocyte differentiation" NARROW []
synonym: "up regulation of chondrocyte differentiation" EXACT []
synonym: "up-regulation of chondrocyte differentiation" EXACT []
synonym: "upregulation of chondrocyte differentiation" EXACT []
is_a: GO:0032330 ! regulation of chondrocyte differentiation
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0061036 ! positive regulation of cartilage development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002062 ! chondrocyte differentiation
relationship: positively_regulates GO:0002062 ! chondrocyte differentiation

[Term]
id: GO:0032365
name: intracellular lipid transport
namespace: biological_process
def: "The directed movement of lipids within cells." [GOC:mah]
is_a: GO:0006869 ! lipid transport
is_a: GO:0046907 ! intracellular transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:18059 ! lipid
intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure

[Term]
id: GO:0032368
name: regulation of lipid transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
is_a: GO:0051049 ! regulation of transport
is_a: GO:1905952 ! regulation of lipid localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006869 ! lipid transport
relationship: regulates GO:0006869 ! lipid transport

[Term]
id: GO:0032369
name: negative regulation of lipid transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
synonym: "down regulation of lipid transport" EXACT []
synonym: "down-regulation of lipid transport" EXACT []
synonym: "downregulation of lipid transport" EXACT []
synonym: "inhibition of lipid transport" NARROW []
is_a: GO:0032368 ! regulation of lipid transport
is_a: GO:0051051 ! negative regulation of transport
is_a: GO:1905953 ! negative regulation of lipid localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006869 ! lipid transport
relationship: negatively_regulates GO:0006869 ! lipid transport

[Term]
id: GO:0032370
name: positive regulation of lipid transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
synonym: "activation of lipid transport" NARROW []
synonym: "stimulation of lipid transport" NARROW []
synonym: "up regulation of lipid transport" EXACT []
synonym: "up-regulation of lipid transport" EXACT []
synonym: "upregulation of lipid transport" EXACT []
is_a: GO:0032368 ! regulation of lipid transport
is_a: GO:0051050 ! positive regulation of transport
is_a: GO:1905954 ! positive regulation of lipid localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006869 ! lipid transport
relationship: positively_regulates GO:0006869 ! lipid transport

[Term]
id: GO:0032377
name: regulation of intracellular lipid transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah]
is_a: GO:0032368 ! regulation of lipid transport
is_a: GO:0032386 ! regulation of intracellular transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032365 ! intracellular lipid transport
relationship: regulates GO:0032365 ! intracellular lipid transport

[Term]
id: GO:0032378
name: negative regulation of intracellular lipid transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah]
synonym: "down regulation of intracellular lipid transport" EXACT []
synonym: "down-regulation of intracellular lipid transport" EXACT []
synonym: "downregulation of intracellular lipid transport" EXACT []
synonym: "inhibition of intracellular lipid transport" NARROW []
is_a: GO:0032369 ! negative regulation of lipid transport
is_a: GO:0032377 ! regulation of intracellular lipid transport
is_a: GO:0032387 ! negative regulation of intracellular transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032365 ! intracellular lipid transport
relationship: negatively_regulates GO:0032365 ! intracellular lipid transport

[Term]
id: GO:0032379
name: positive regulation of intracellular lipid transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah]
synonym: "activation of intracellular lipid transport" NARROW []
synonym: "stimulation of intracellular lipid transport" NARROW []
synonym: "up regulation of intracellular lipid transport" EXACT []
synonym: "up-regulation of intracellular lipid transport" EXACT []
synonym: "upregulation of intracellular lipid transport" EXACT []
is_a: GO:0032370 ! positive regulation of lipid transport
is_a: GO:0032377 ! regulation of intracellular lipid transport
is_a: GO:0032388 ! positive regulation of intracellular transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032365 ! intracellular lipid transport
relationship: positively_regulates GO:0032365 ! intracellular lipid transport

[Term]
id: GO:0032386
name: regulation of intracellular transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah]
is_a: GO:0051049 ! regulation of transport
is_a: GO:0060341 ! regulation of cellular localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0046907 ! intracellular transport
relationship: regulates GO:0046907 ! intracellular transport

[Term]
id: GO:0032387
name: negative regulation of intracellular transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah]
synonym: "down regulation of intracellular transport" EXACT []
synonym: "down-regulation of intracellular transport" EXACT []
synonym: "downregulation of intracellular transport" EXACT []
synonym: "inhibition of intracellular transport" NARROW []
is_a: GO:0032386 ! regulation of intracellular transport
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051051 ! negative regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0046907 ! intracellular transport
relationship: negatively_regulates GO:0046907 ! intracellular transport

[Term]
id: GO:0032388
name: positive regulation of intracellular transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah]
synonym: "activation of intracellular transport" NARROW []
synonym: "stimulation of intracellular transport" NARROW []
synonym: "up regulation of intracellular transport" EXACT []
synonym: "up-regulation of intracellular transport" EXACT []
synonym: "upregulation of intracellular transport" EXACT []
is_a: GO:0032386 ! regulation of intracellular transport
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051050 ! positive regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0046907 ! intracellular transport
relationship: positively_regulates GO:0046907 ! intracellular transport

[Term]
id: GO:0032409
name: regulation of transporter activity
namespace: biological_process
def: "Any process that modulates the activity of a transporter." [GOC:mah]
subset: gocheck_do_not_annotate
is_a: GO:0065009 ! regulation of molecular function
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0005215 ! transporter activity
relationship: regulates GO:0005215 ! transporter activity

[Term]
id: GO:0032410
name: negative regulation of transporter activity
namespace: biological_process
def: "Any process that stops or reduces the activity of a transporter." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "down regulation of transporter activity" EXACT []
synonym: "down-regulation of transporter activity" EXACT []
synonym: "downregulation of transporter activity" EXACT []
synonym: "inhibition of transporter activity" NARROW []
is_a: GO:0032409 ! regulation of transporter activity
is_a: GO:0044092 ! negative regulation of molecular function
is_a: GO:0051051 ! negative regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0005215 ! transporter activity
relationship: negatively_regulates GO:0005215 ! transporter activity

[Term]
id: GO:0032411
name: positive regulation of transporter activity
namespace: biological_process
def: "Any process that activates or increases the activity of a transporter." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "activation of transporter activity" NARROW []
synonym: "stimulation of transporter activity" NARROW []
synonym: "up regulation of transporter activity" EXACT []
synonym: "up-regulation of transporter activity" EXACT []
synonym: "upregulation of transporter activity" EXACT []
is_a: GO:0032409 ! regulation of transporter activity
is_a: GO:0044093 ! positive regulation of molecular function
is_a: GO:0051050 ! positive regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0005215 ! transporter activity
relationship: positively_regulates GO:0005215 ! transporter activity

[Term]
id: GO:0032412
name: regulation of monoatomic ion transmembrane transporter activity
namespace: biological_process
def: "Any process that modulates the activity of an ion transporter." [GOC:mah, GOC:tb]
subset: gocheck_do_not_annotate
synonym: "regulation of ion transmembrane transporter activity" BROAD []
synonym: "regulation of ion transporter activity" EXACT [GOC:tb]
is_a: GO:0022898 ! regulation of transmembrane transporter activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0015075 ! monoatomic ion transmembrane transporter activity
relationship: regulates GO:0015075 ! monoatomic ion transmembrane transporter activity

[Term]
id: GO:0032413
name: negative regulation of ion transmembrane transporter activity
namespace: biological_process
def: "Any process that stops or reduces the activity of an ion transporter." [GOC:mah, GOC:tb]
subset: gocheck_do_not_annotate
synonym: "down regulation of ion transporter activity" EXACT []
synonym: "down-regulation of ion transporter activity" EXACT []
synonym: "downregulation of ion transporter activity" EXACT []
synonym: "inhibition of ion transporter activity" NARROW []
synonym: "negative regulation of ion transporter activity" EXACT [GOC:tb]
is_a: GO:0032410 ! negative regulation of transporter activity
is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity
is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity
relationship: negatively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity

[Term]
id: GO:0032414
name: positive regulation of ion transmembrane transporter activity
namespace: biological_process
def: "Any process that activates or increases the activity of an ion transporter." [GOC:mah, GOC:tb]
subset: gocheck_do_not_annotate
synonym: "activation of ion transporter activity" NARROW []
synonym: "positive regulation of ion transporter activity" EXACT [GOC:tb]
synonym: "stimulation of ion transporter activity" NARROW []
synonym: "up regulation of ion transporter activity" EXACT []
synonym: "up-regulation of ion transporter activity" EXACT []
synonym: "upregulation of ion transporter activity" EXACT []
is_a: GO:0032411 ! positive regulation of transporter activity
is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity
is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity
relationship: positively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity

[Term]
id: GO:0032432
name: actin filament bundle
namespace: cellular_component
alt_id: GO:0000141
alt_id: GO:0030482
def: "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:mah]
synonym: "actin cable" RELATED [GOC:mah]
is_a: GO:0110165 ! cellular anatomical entity
relationship: has_part GO:0005884 ! actin filament
relationship: part_of GO:0015629 ! actin cytoskeleton

[Term]
id: GO:0032501
name: multicellular organismal process
namespace: biological_process
alt_id: GO:0044707
alt_id: GO:0050874
def: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb]
subset: gocheck_do_not_annotate
subset: goslim_pir
synonym: "organismal physiological process" EXACT []
synonym: "single-multicellular organism process" RELATED []
is_a: GO:0008150 ! biological process
property_value: RO:0002161 NCBITaxon:2
property_value: RO:0002161 NCBITaxon:2157
property_value: RO:0002161 NCBITaxon:4896
property_value: RO:0002161 NCBITaxon:4932
created_by: jl
creation_date: 2012-09-19T16:07:47Z

[Term]
id: GO:0032502
name: developmental process
namespace: biological_process
alt_id: GO:0044767
def: "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete]
subset: goslim_agr
subset: goslim_flybase_ribbon
subset: goslim_pir
synonym: "development" NARROW []
synonym: "single-organism developmental process" RELATED []
is_a: GO:0008150 ! biological process
created_by: jl
creation_date: 2012-12-19T12:21:31Z

[Term]
id: GO:0032504
name: multicellular organism reproduction
namespace: biological_process
def: "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete, GOC:jid]
subset: goslim_drosophila
is_a: GO:0000003 ! reproduction
is_a: GO:0032501 ! multicellular organismal process

[Term]
id: GO:0032528
name: microvillus organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah]
synonym: "microvillus organisation" EXACT [GOC:mah]
synonym: "microvillus organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0120036 ! plasma membrane bounded cell projection organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005902 ! microvillus
relationship: results_in_organization_of GO:0005902 ! microvillus
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0032530
name: regulation of microvillus organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus." [GOC:mah]
synonym: "regulation of microvillus organisation" EXACT [GOC:mah]
synonym: "regulation of microvillus organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032528 ! microvillus organization
relationship: regulates GO:0032528 ! microvillus organization

[Term]
id: GO:0032534
name: regulation of microvillus assembly
namespace: biological_process
def: "A process that modulates the formation of a microvillus." [GOC:mah]
synonym: "regulation of microvillus biogenesis" RELATED [GOC:mah]
is_a: GO:0032530 ! regulation of microvillus organization
is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030033 ! microvillus assembly
relationship: regulates GO:0030033 ! microvillus assembly

[Term]
id: GO:0032589
name: neuron projection membrane
namespace: cellular_component
def: "The portion of the plasma membrane surrounding a neuron projection." [GOC:mah]
is_a: GO:0031253 ! cell projection membrane
is_a: GO:0031256 ! leading edge membrane
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0043005 ! neuron projection
relationship: bounding_layer_of GO:0043005 ! neuron projection
relationship: part_of GO:0043005 ! neuron projection

[Term]
id: GO:0032594
name: protein transport within lipid bilayer
namespace: biological_process
def: "The directed movement of a protein from one location to another within a lipid bilayer." [GOC:mah]
synonym: "protein translocation within membrane" EXACT []
synonym: "receptor translocation within membrane" NARROW []
synonym: "receptor transport within lipid bilayer" NARROW []
is_a: GO:0006886 ! intracellular protein transport
is_a: GO:0061024 ! membrane organization
intersection_of: GO:0015031 ! protein transport
intersection_of: occurs_in GO:0016020 ! membrane
relationship: occurs_in GO:0016020 ! membrane

[Term]
id: GO:0032774
name: RNA biosynthetic process
namespace: biological_process
alt_id: GO:0062103
def: "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." [GOC:mah, GOC:txnOH]
comment: Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study.
subset: gocheck_do_not_annotate
synonym: "double-stranded RNA biosynthesis" NARROW []
synonym: "double-stranded RNA biosynthetic process" NARROW []
synonym: "dsRNA biosynthesis" NARROW []
synonym: "dsRNA biosynthetic process" NARROW [GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:rl]
synonym: "RNA anabolism" EXACT []
synonym: "RNA biosynthesis" EXACT []
synonym: "RNA formation" EXACT []
synonym: "RNA synthesis" EXACT []
is_a: GO:0009059 ! macromolecule biosynthetic process
is_a: GO:0016070 ! RNA metabolic process
is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process
intersection_of: GO:0009059 ! macromolecule biosynthetic process
intersection_of: has_primary_output CHEBI:33697 ! ribonucleic acid
relationship: has_primary_output CHEBI:33697 ! ribonucleic acid

[Term]
id: GO:0032782
name: bile acid secretion
namespace: biological_process
def: "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue." [GOC:ecd]
is_a: GO:0015718 ! monocarboxylic acid transport
is_a: GO:0046717 ! acid secretion
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input CHEBI:36235 ! bile acid anion
relationship: has_primary_input CHEBI:36235 ! bile acid anion

[Term]
id: GO:0032787
name: monocarboxylic acid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)." [GOC:vk]
subset: goslim_yeast
synonym: "monocarboxylate metabolic process" EXACT []
synonym: "monocarboxylic acid metabolism" EXACT []
is_a: GO:0019752 ! carboxylic acid metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:35757 ! monocarboxylic acid anion
relationship: has_primary_input_or_output CHEBI:35757 ! monocarboxylic acid anion

[Term]
id: GO:0032790
name: ribosome disassembly
namespace: biological_process
def: "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits." [GOC:mah, GOC:vk]
synonym: "ribosome dissociation factor" RELATED []
synonym: "ribosome recycling" NARROW [GOC:db, PMID:9463391]
is_a: GO:1903008 ! organelle disassembly
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0005840 ! ribosome
relationship: results_in_disassembly_of GO:0005840 ! ribosome

[Term]
id: GO:0032838
name: plasma membrane bounded cell projection cytoplasm
namespace: cellular_component
def: "All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection." [GOC:krc, GOC:mah]
is_a: GO:0099568 ! cytoplasmic region
intersection_of: GO:0005737 ! cytoplasm
intersection_of: part_of GO:0120025 ! plasma membrane bounded cell projection
relationship: part_of GO:0120025 ! plasma membrane bounded cell projection

[Term]
id: GO:0032868
name: response to insulin
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [GOC:mah, ISBN:0198506732]
synonym: "response to insulin stimulus" EXACT [GOC:dos]
is_a: GO:0043434 ! response to peptide hormone
intersection_of: GO:0042221 ! response to chemical
intersection_of: has_primary_input PR:000009054 ! insulin gene translation product
relationship: has_primary_input PR:000009054 ! insulin gene translation product

[Term]
id: GO:0032871
name: regulation of karyogamy
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion." [GOC:mah]
is_a: GO:1903353 ! regulation of nucleus organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0000741 ! karyogamy
relationship: regulates GO:0000741 ! karyogamy

[Term]
id: GO:0032878
name: regulation of establishment or maintenance of cell polarity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007163 ! establishment or maintenance of cell polarity
relationship: regulates GO:0007163 ! establishment or maintenance of cell polarity

[Term]
id: GO:0032879
name: regulation of localization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." [GOC:mah]
synonym: "regulation of localisation" EXACT [GOC:mah]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051179 ! localization
relationship: regulates GO:0051179 ! localization

[Term]
id: GO:0032880
name: regulation of protein localization
namespace: biological_process
alt_id: GO:1903827
def: "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." [GOC:dph, GOC:mah, GOC:tb]
subset: goslim_chembl
synonym: "regulation of cellular protein localisation" EXACT [GOC:TermGenie]
synonym: "regulation of cellular protein localization" EXACT []
synonym: "regulation of protein localisation" EXACT [GOC:mah]
is_a: GO:0060341 ! regulation of cellular localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008104 ! protein localization
relationship: regulates GO:0008104 ! protein localization
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI
created_by: jl
creation_date: 2015-01-20T14:32:14Z

[Term]
id: GO:0032881
name: regulation of polysaccharide metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides." [GOC:mah]
is_a: GO:0006109 ! regulation of carbohydrate metabolic process
is_a: GO:0060255 ! regulation of macromolecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0005976 ! polysaccharide metabolic process
relationship: regulates GO:0005976 ! polysaccharide metabolic process

[Term]
id: GO:0032882
name: regulation of chitin metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin." [GOC:mah]
synonym: "regulation of chitin metabolism" EXACT []
is_a: GO:0032881 ! regulation of polysaccharide metabolic process
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006030 ! chitin metabolic process
relationship: regulates GO:0006030 ! chitin metabolic process

[Term]
id: GO:0032883
name: regulation of chitin biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin." [GOC:mah]
synonym: "regulation of chitin anabolism" EXACT []
synonym: "regulation of chitin biosynthesis" RELATED []
synonym: "regulation of chitin formation" EXACT []
synonym: "regulation of chitin synthesis" EXACT []
is_a: GO:0032882 ! regulation of chitin metabolic process
is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006031 ! chitin biosynthetic process
relationship: regulates GO:0006031 ! chitin biosynthetic process

[Term]
id: GO:0032885
name: regulation of polysaccharide biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides." [GOC:mah]
is_a: GO:0010556 ! regulation of macromolecule biosynthetic process
is_a: GO:0032881 ! regulation of polysaccharide metabolic process
is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0000271 ! polysaccharide biosynthetic process
relationship: regulates GO:0000271 ! polysaccharide biosynthetic process

[Term]
id: GO:0032886
name: regulation of microtubule-based process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." [GOC:mah]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007017 ! microtubule-based process
relationship: regulates GO:0007017 ! microtubule-based process

[Term]
id: GO:0032890
name: regulation of organic acid transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0015849 ! organic acid transport
relationship: regulates GO:0015849 ! organic acid transport

[Term]
id: GO:0032891
name: negative regulation of organic acid transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
synonym: "down regulation of organic acid transport" EXACT []
synonym: "down-regulation of organic acid transport" EXACT []
synonym: "downregulation of organic acid transport" EXACT []
synonym: "inhibition of organic acid transport" NARROW []
is_a: GO:0032890 ! regulation of organic acid transport
is_a: GO:0051051 ! negative regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0015849 ! organic acid transport
relationship: negatively_regulates GO:0015849 ! organic acid transport

[Term]
id: GO:0032892
name: positive regulation of organic acid transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
synonym: "activation of organic acid transport" NARROW []
synonym: "stimulation of organic acid transport" NARROW []
synonym: "up regulation of organic acid transport" EXACT []
synonym: "up-regulation of organic acid transport" EXACT []
synonym: "upregulation of organic acid transport" EXACT []
is_a: GO:0032890 ! regulation of organic acid transport
is_a: GO:0051050 ! positive regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0015849 ! organic acid transport
relationship: positively_regulates GO:0015849 ! organic acid transport

[Term]
id: GO:0032940
name: secretion by cell
namespace: biological_process
def: "The controlled release of a substance by a cell." [GOC:mah]
synonym: "cellular secretion" EXACT []
xref: Wikipedia:Secretion
is_a: GO:0046903 ! secretion
is_a: GO:0140352 ! export from cell

[Term]
id: GO:0032941
name: secretion by tissue
namespace: biological_process
def: "The controlled release of a substance by a tissue." [GOC:mah]
synonym: "expulsion of gland contents" RELATED [GOC:mah]
synonym: "tissue secretion" EXACT []
is_a: GO:0032501 ! multicellular organismal process
is_a: GO:0046903 ! secretion

[Term]
id: GO:0032943
name: mononuclear cell proliferation
namespace: biological_process
def: "The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form." [GOC:add]
synonym: "PBMC proliferation" NARROW []
synonym: "peripheral blood mononuclear cell proliferation" NARROW []
is_a: GO:0070661 ! leukocyte proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000842 ! mononuclear cell
relationship: acts_on_population_of CL:0000842 ! mononuclear cell

[Term]
id: GO:0032944
name: regulation of mononuclear cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation." [GOC:add]
synonym: "regulation of PBMC proliferation" NARROW []
synonym: "regulation of peripheral blood mononuclear cell proliferation" NARROW []
is_a: GO:0070663 ! regulation of leukocyte proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032943 ! mononuclear cell proliferation
relationship: regulates GO:0032943 ! mononuclear cell proliferation

[Term]
id: GO:0032945
name: negative regulation of mononuclear cell proliferation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation." [GOC:add]
synonym: "negative regulation of PBMC proliferation" NARROW []
synonym: "negative regulation of peripheral blood mononuclear cell proliferation" NARROW []
is_a: GO:0032944 ! regulation of mononuclear cell proliferation
is_a: GO:0070664 ! negative regulation of leukocyte proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032943 ! mononuclear cell proliferation
relationship: negatively_regulates GO:0032943 ! mononuclear cell proliferation

[Term]
id: GO:0032946
name: positive regulation of mononuclear cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation." [GOC:add]
synonym: "activation of mononuclear cell proliferation" NARROW []
synonym: "positive regulation of PBMC proliferation" NARROW []
synonym: "positive regulation of peripheral blood mononuclear cell proliferation" NARROW []
synonym: "stimulation of mononuclear cell proliferation" NARROW []
synonym: "up regulation of mononuclear cell proliferation" EXACT []
synonym: "up-regulation of mononuclear cell proliferation" EXACT []
synonym: "upregulation of mononuclear cell proliferation" EXACT []
is_a: GO:0032944 ! regulation of mononuclear cell proliferation
is_a: GO:0070665 ! positive regulation of leukocyte proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032943 ! mononuclear cell proliferation
relationship: positively_regulates GO:0032943 ! mononuclear cell proliferation

[Term]
id: GO:0032956
name: regulation of actin cytoskeleton organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:mah]
synonym: "regulation of actin cytoskeleton organisation" EXACT [GOC:mah]
synonym: "regulation of actin cytoskeleton organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0032970 ! regulation of actin filament-based process
is_a: GO:0051493 ! regulation of cytoskeleton organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030036 ! actin cytoskeleton organization
relationship: regulates GO:0030036 ! actin cytoskeleton organization

[Term]
id: GO:0032963
name: collagen metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732]
synonym: "collagen metabolism" EXACT []
is_a: GO:0008152 ! metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output GO:0005581 ! collagen trimer
relationship: has_primary_input_or_output GO:0005581 ! collagen trimer

[Term]
id: GO:0032964
name: collagen biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732]
synonym: "collagen anabolism" EXACT []
synonym: "collagen biosynthesis" EXACT []
synonym: "collagen formation" EXACT []
synonym: "collagen synthesis" EXACT []
is_a: GO:0009058 ! biosynthetic process
is_a: GO:0032963 ! collagen metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output GO:0005581 ! collagen trimer
relationship: has_primary_output GO:0005581 ! collagen trimer

[Term]
id: GO:0032965
name: regulation of collagen biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah]
synonym: "regulation of collagen anabolism" EXACT []
synonym: "regulation of collagen biosynthesis" EXACT []
synonym: "regulation of collagen formation" EXACT []
synonym: "regulation of collagen synthesis" EXACT []
is_a: GO:0009889 ! regulation of biosynthetic process
is_a: GO:0010712 ! regulation of collagen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032964 ! collagen biosynthetic process
relationship: regulates GO:0032964 ! collagen biosynthetic process

[Term]
id: GO:0032966
name: negative regulation of collagen biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah]
synonym: "negative regulation of collagen anabolism" EXACT []
synonym: "negative regulation of collagen biosynthesis" EXACT []
synonym: "negative regulation of collagen formation" EXACT []
synonym: "negative regulation of collagen synthesis" EXACT []
is_a: GO:0009890 ! negative regulation of biosynthetic process
is_a: GO:0010713 ! negative regulation of collagen metabolic process
is_a: GO:0032965 ! regulation of collagen biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032964 ! collagen biosynthetic process
relationship: negatively_regulates GO:0032964 ! collagen biosynthetic process

[Term]
id: GO:0032967
name: positive regulation of collagen biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah]
synonym: "positive regulation of collagen anabolism" EXACT []
synonym: "positive regulation of collagen biosynthesis" EXACT []
synonym: "positive regulation of collagen formation" EXACT []
synonym: "positive regulation of collagen synthesis" EXACT []
is_a: GO:0009891 ! positive regulation of biosynthetic process
is_a: GO:0010714 ! positive regulation of collagen metabolic process
is_a: GO:0032965 ! regulation of collagen biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032964 ! collagen biosynthetic process
relationship: positively_regulates GO:0032964 ! collagen biosynthetic process

[Term]
id: GO:0032970
name: regulation of actin filament-based process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." [GOC:mah]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030029 ! actin filament-based process
relationship: regulates GO:0030029 ! actin filament-based process

[Term]
id: GO:0032984
name: protein-containing complex disassembly
namespace: biological_process
alt_id: GO:0034623
alt_id: GO:0043241
alt_id: GO:0043624
def: "The disaggregation of a protein-containing macromolecular complex into its constituent components." [GOC:mah]
synonym: "cellular macromolecule complex disassembly" RELATED []
synonym: "cellular protein complex disassembly" RELATED []
synonym: "macromolecule complex disassembly" RELATED []
synonym: "protein complex disassembly" EXACT []
is_a: GO:0022411 ! cellular component disassembly
is_a: GO:0043933 ! protein-containing complex organization
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0032991 ! protein-containing complex
relationship: results_in_disassembly_of GO:0032991 ! protein-containing complex
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI

[Term]
id: GO:0032986
name: protein-DNA complex disassembly
namespace: biological_process
def: "The disaggregation of a protein-DNA complex into its constituent components." [GOC:mah]
synonym: "DNA-protein complex disassembly" EXACT [GOC:mah]
is_a: GO:0032984 ! protein-containing complex disassembly
is_a: GO:0071824 ! protein-DNA complex organization
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0032993 ! protein-DNA complex
relationship: results_in_disassembly_of GO:0032993 ! protein-DNA complex

[Term]
id: GO:0032988
name: protein-RNA complex disassembly
namespace: biological_process
def: "The disaggregation of a protein-RNA complex into its constituent components." [GOC:mah]
synonym: "ribonucleoprotein complex disassembly" EXACT []
synonym: "RNA-protein complex disassembly" EXACT []
synonym: "RNP complex disassembly" EXACT []
is_a: GO:0032984 ! protein-containing complex disassembly
is_a: GO:0071826 ! protein-RNA complex organization
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:1990904 ! ribonucleoprotein complex
relationship: results_in_disassembly_of GO:1990904 ! ribonucleoprotein complex
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25143" xsd:anyURI

[Term]
id: GO:0032989
name: cellular anatomical entity morphogenesis
namespace: biological_process
def: "The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system." [GOC:dph, GOC:mah, GOC:tb]
subset: goslim_pir
synonym: "cellular component morphogenesis" EXACT []
synonym: "cellular structure morphogenesis" EXACT [GOC:dph, GOC:tb]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of GO:0110165 ! cellular anatomical entity
relationship: results_in_morphogenesis_of GO:0110165 ! cellular anatomical entity
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25496" xsd:anyURI
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26249" xsd:anyURI

[Term]
id: GO:0032991
name: protein-containing complex
namespace: cellular_component
alt_id: GO:0043234
def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." [GOC:dos, GOC:mah]
comment: A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole.
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_pir
synonym: "macromolecular complex" EXACT []
synonym: "macromolecule complex" EXACT []
synonym: "protein complex" NARROW []
synonym: "protein containing complex" EXACT []
synonym: "protein-protein complex" NARROW []
is_a: GO:0005575 ! cellular_component
is_a: PR:000050567 ! protein-containing material entity
disjoint_from: GO:0110165 ! cellular anatomical entity

[Term]
id: GO:0032993
name: protein-DNA complex
namespace: cellular_component
def: "A macromolecular complex containing both protein and DNA molecules." [GOC:mah]
comment: Note that this term is intended to classify complexes that have DNA as one of the members of the complex, that is, the complex does not exist if DNA is not present. Protein complexes that interact with DNA e.g. transcription factor complexes should not be classified here.
subset: goslim_pir
synonym: "DNA-protein complex" EXACT [GOC:mah]
is_a: GO:0032991 ! protein-containing complex
relationship: has_part CHEBI:16991 ! deoxyribonucleic acid

[Term]
id: GO:0033002
name: muscle cell proliferation
namespace: biological_process
def: "The expansion of a muscle cell population by cell division." [CL:0000187, GOC:mah]
synonym: "myocyte proliferation" EXACT []
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000187 ! muscle cell
relationship: acts_on_population_of CL:0000187 ! muscle cell

[Term]
id: GO:0033013
name: tetrapyrrole metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah]
subset: goslim_pombe
subset: goslim_prokaryote
synonym: "tetrapyrrole metabolism" EXACT []
is_a: GO:0006725 ! cellular aromatic compound metabolic process
is_a: GO:0046483 ! heterocycle metabolic process
is_a: GO:1901360 ! organic cyclic compound metabolic process
is_a: GO:1901564 ! organonitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:26932 ! tetrapyrrole
relationship: has_primary_input_or_output CHEBI:26932 ! tetrapyrrole

[Term]
id: GO:0033014
name: tetrapyrrole biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah]
synonym: "tetrapyrrole anabolism" EXACT []
synonym: "tetrapyrrole biosynthesis" EXACT []
synonym: "tetrapyrrole formation" EXACT []
synonym: "tetrapyrrole synthesis" EXACT []
is_a: GO:0018130 ! heterocycle biosynthetic process
is_a: GO:0019438 ! aromatic compound biosynthetic process
is_a: GO:0033013 ! tetrapyrrole metabolic process
is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process
is_a: GO:1901362 ! organic cyclic compound biosynthetic process
is_a: GO:1901566 ! organonitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:26932 ! tetrapyrrole
relationship: has_primary_output CHEBI:26932 ! tetrapyrrole

[Term]
id: GO:0033015
name: tetrapyrrole catabolic process
namespace: biological_process
def: "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah]
synonym: "tetrapyrrole breakdown" EXACT []
synonym: "tetrapyrrole catabolism" EXACT []
synonym: "tetrapyrrole degradation" EXACT []
is_a: GO:0019439 ! aromatic compound catabolic process
is_a: GO:0033013 ! tetrapyrrole metabolic process
is_a: GO:0044270 ! cellular nitrogen compound catabolic process
is_a: GO:0046700 ! heterocycle catabolic process
is_a: GO:1901361 ! organic cyclic compound catabolic process
is_a: GO:1901565 ! organonitrogen compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:26932 ! tetrapyrrole
relationship: has_primary_input CHEBI:26932 ! tetrapyrrole

[Term]
id: GO:0033028
name: myeloid cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [CL:0000763, GOC:add, GOC:mtg_apoptosis, PMID:11292031, PMID:15330259, PMID:17133093]
synonym: "apoptosis of myeloid cells" EXACT []
synonym: "myeloid cell apoptosis" NARROW []
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000763 ! myeloid cell
relationship: occurs_in CL:0000763 ! myeloid cell

[Term]
id: GO:0033032
name: regulation of myeloid cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis]
synonym: "regulation of myeloid cell apoptosis" NARROW []
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0033028 ! myeloid cell apoptotic process
relationship: regulates GO:0033028 ! myeloid cell apoptotic process

[Term]
id: GO:0033033
name: negative regulation of myeloid cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis]
synonym: "down regulation of myeloid cell apoptosis" EXACT []
synonym: "down-regulation of myeloid cell apoptosis" EXACT []
synonym: "downregulation of myeloid cell apoptosis" EXACT []
synonym: "inhibition of myeloid cell apoptosis" NARROW []
synonym: "negative regulation of myeloid cell apoptosis" NARROW []
is_a: GO:0033032 ! regulation of myeloid cell apoptotic process
is_a: GO:0043066 ! negative regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0033028 ! myeloid cell apoptotic process
relationship: negatively_regulates GO:0033028 ! myeloid cell apoptotic process

[Term]
id: GO:0033034
name: positive regulation of myeloid cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis]
synonym: "activation of myeloid cell apoptosis" NARROW []
synonym: "positive regulation of myeloid cell apoptosis" NARROW []
synonym: "stimulation of myeloid cell apoptosis" NARROW []
synonym: "up regulation of myeloid cell apoptosis" EXACT []
synonym: "up-regulation of myeloid cell apoptosis" EXACT []
synonym: "upregulation of myeloid cell apoptosis" EXACT []
is_a: GO:0033032 ! regulation of myeloid cell apoptotic process
is_a: GO:0043065 ! positive regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0033028 ! myeloid cell apoptotic process
relationship: positively_regulates GO:0033028 ! myeloid cell apoptotic process

[Term]
id: GO:0033036
name: macromolecule localization
namespace: biological_process
def: "Any process in which a macromolecule is transported to, or maintained in, a specific location." [GOC:mah]
subset: goslim_flybase_ribbon
synonym: "macromolecule localisation" EXACT [GOC:mah]
is_a: GO:0051179 ! localization

[Term]
id: GO:0033037
name: polysaccharide localization
namespace: biological_process
def: "Any process in which a polysaccharide is transported to, or maintained in, a specific location." [GOC:mah]
synonym: "polysaccharide localisation" EXACT [GOC:mah]
is_a: GO:0033036 ! macromolecule localization
intersection_of: GO:0033036 ! macromolecule localization
intersection_of: has_primary_input CHEBI:18154 ! polysaccharide
relationship: has_primary_input CHEBI:18154 ! polysaccharide

[Term]
id: GO:0033043
name: regulation of organelle organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:mah]
subset: goslim_yeast
synonym: "regulation of organelle organisation" EXACT [GOC:mah]
synonym: "regulation of organelle organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006996 ! organelle organization
relationship: regulates GO:0006996 ! organelle organization

[Term]
id: GO:0033044
name: regulation of chromosome organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." [GOC:mah]
synonym: "regulation of chromosome organisation" EXACT [GOC:mah]
synonym: "regulation of chromosome organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0033043 ! regulation of organelle organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051276 ! chromosome organization
relationship: regulates GO:0051276 ! chromosome organization

[Term]
id: GO:0033045
name: regulation of sister chromatid segregation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation." [GOC:mah]
is_a: GO:0033044 ! regulation of chromosome organization
is_a: GO:0051983 ! regulation of chromosome segregation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0000819 ! sister chromatid segregation
relationship: regulates GO:0000819 ! sister chromatid segregation

[Term]
id: GO:0033046
name: negative regulation of sister chromatid segregation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." [GOC:mah]
is_a: GO:0033045 ! regulation of sister chromatid segregation
is_a: GO:0051985 ! negative regulation of chromosome segregation
is_a: GO:2001251 ! negative regulation of chromosome organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0000819 ! sister chromatid segregation
relationship: negatively_regulates GO:0000819 ! sister chromatid segregation

[Term]
id: GO:0033047
name: regulation of mitotic sister chromatid segregation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah]
is_a: GO:0033045 ! regulation of sister chromatid segregation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0000070 ! mitotic sister chromatid segregation
relationship: regulates GO:0000070 ! mitotic sister chromatid segregation

[Term]
id: GO:0033048
name: negative regulation of mitotic sister chromatid segregation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah]
is_a: GO:0033046 ! negative regulation of sister chromatid segregation
is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0000070 ! mitotic sister chromatid segregation
relationship: negatively_regulates GO:0000070 ! mitotic sister chromatid segregation

[Term]
id: GO:0033059
name: cellular pigmentation
namespace: biological_process
def: "The deposition or aggregation of coloring matter in a cell." [GOC:mtg_MIT_16mar07]
is_a: GO:0009987 ! cellular process
is_a: GO:0043473 ! pigmentation

[Term]
id: GO:0033157
name: regulation of intracellular protein transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells." [GOC:mah]
is_a: GO:0032386 ! regulation of intracellular transport
is_a: GO:0051223 ! regulation of protein transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006886 ! intracellular protein transport
relationship: regulates GO:0006886 ! intracellular protein transport

[Term]
id: GO:0033238
name: regulation of amine metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." [GOC:mah]
synonym: "regulation of amine metabolism" EXACT []
synonym: "regulation of cellular amine metabolic process" EXACT []
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009308 ! amine metabolic process
relationship: regulates GO:0009308 ! amine metabolic process

[Term]
id: GO:0033239
name: negative regulation of amine metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah]
synonym: "negative regulation of amine metabolism" EXACT []
synonym: "negative regulation of cellular amine metabolic process" EXACT []
is_a: GO:0033238 ! regulation of amine metabolic process
is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009308 ! amine metabolic process
relationship: negatively_regulates GO:0009308 ! amine metabolic process

[Term]
id: GO:0033240
name: positive regulation of amine metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah]
synonym: "positive regulation of amine metabolism" EXACT []
synonym: "positive regulation of cellular amine metabolic process" EXACT []
is_a: GO:0033238 ! regulation of amine metabolic process
is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009308 ! amine metabolic process
relationship: positively_regulates GO:0009308 ! amine metabolic process

[Term]
id: GO:0033241
name: regulation of amine catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah]
synonym: "regulation of amine breakdown" EXACT []
synonym: "regulation of amine catabolism" EXACT []
synonym: "regulation of amine degradation" EXACT []
synonym: "regulation of cellular amine catabolic process" EXACT []
is_a: GO:0009894 ! regulation of catabolic process
is_a: GO:0033238 ! regulation of amine metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009310 ! amine catabolic process
relationship: regulates GO:0009310 ! amine catabolic process

[Term]
id: GO:0033242
name: negative regulation of amine catabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah]
synonym: "negative regulation of amine breakdown" EXACT []
synonym: "negative regulation of amine catabolism" EXACT []
synonym: "negative regulation of amine degradation" EXACT []
synonym: "negative regulation of cellular amine catabolic process" EXACT []
is_a: GO:0009895 ! negative regulation of catabolic process
is_a: GO:0033239 ! negative regulation of amine metabolic process
is_a: GO:0033241 ! regulation of amine catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009310 ! amine catabolic process
relationship: negatively_regulates GO:0009310 ! amine catabolic process

[Term]
id: GO:0033243
name: positive regulation of amine catabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah]
synonym: "positive regulation of amine breakdown" EXACT []
synonym: "positive regulation of amine catabolism" EXACT []
synonym: "positive regulation of amine degradation" EXACT []
is_a: GO:0009896 ! positive regulation of catabolic process
is_a: GO:0033240 ! positive regulation of amine metabolic process
is_a: GO:0033241 ! regulation of amine catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009310 ! amine catabolic process
relationship: positively_regulates GO:0009310 ! amine catabolic process

[Term]
id: GO:0033278
name: cell proliferation in midbrain
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain." [GO_REF:0000021, GOC:dgf]
synonym: "cell proliferation in mesencephalon" EXACT []
synonym: "mesencepahalic cell proliferation" RELATED []
is_a: GO:0061351 ! neural precursor cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: occurs_in UBERON:0001891 ! midbrain
relationship: occurs_in UBERON:0001891 ! midbrain
relationship: part_of GO:0030901 ! midbrain development

[Term]
id: GO:0033363
name: secretory granule organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah]
synonym: "secretory granule organisation" EXACT [GOC:mah]
synonym: "secretory granule organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0016050 ! vesicle organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0030141 ! secretory granule
relationship: part_of GO:0010256 ! endomembrane system organization
relationship: results_in_organization_of GO:0030141 ! secretory granule

[Term]
id: GO:0033365
name: protein localization to organelle
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within an organelle." [GOC:mah]
synonym: "protein localisation to organelle" EXACT [GOC:mah]
synonym: "protein localization in organelle" EXACT [GOC:mah]
is_a: GO:0008104 ! protein localization
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0043226 ! organelle
relationship: has_target_end_location GO:0043226 ! organelle

[Term]
id: GO:0033366
name: protein localization to secretory granule
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a secretory granule." [GOC:mah]
synonym: "protein localisation in secretory granule" EXACT [GOC:mah]
synonym: "protein localization in secretory granule" EXACT []
is_a: GO:0033365 ! protein localization to organelle
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0030141 ! secretory granule
relationship: has_target_end_location GO:0030141 ! secretory granule

[Term]
id: GO:0033371
name: T cell secretory granule organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah]
synonym: "T cell secretory granule organisation" EXACT [GOC:mah]
synonym: "T cell secretory granule organization and biogenesis" RELATED [GOC:mah]
synonym: "T lymphocyte secretory granule organization" EXACT []
synonym: "T-cell secretory granule organization" EXACT []
synonym: "T-lymphocyte secretory granule maturation" RELATED []
synonym: "T-lymphocyte secretory granule organization" EXACT []
is_a: GO:0033363 ! secretory granule organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: occurs_in CL:0000084 ! T cell
intersection_of: results_in_organization_of GO:0030141 ! secretory granule
relationship: occurs_in CL:0000084 ! T cell

[Term]
id: GO:0033604
name: negative regulation of catecholamine secretion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah]
synonym: "down regulation of catecholamine secretion" EXACT []
synonym: "down-regulation of catecholamine secretion" EXACT []
synonym: "downregulation of catecholamine secretion" EXACT []
synonym: "inhibition of catecholamine secretion" NARROW []
is_a: GO:0050433 ! regulation of catecholamine secretion
is_a: GO:0051953 ! negative regulation of amine transport
is_a: GO:1903531 ! negative regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0050432 ! catecholamine secretion
relationship: negatively_regulates GO:0050432 ! catecholamine secretion

[Term]
id: GO:0033605
name: positive regulation of catecholamine secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah]
synonym: "activation of catecholamine secretion" NARROW []
synonym: "stimulation of catecholamine secretion" NARROW []
synonym: "up regulation of catecholamine secretion" EXACT []
synonym: "up-regulation of catecholamine secretion" EXACT []
synonym: "upregulation of catecholamine secretion" EXACT []
is_a: GO:0050433 ! regulation of catecholamine secretion
is_a: GO:0051954 ! positive regulation of amine transport
is_a: GO:1903532 ! positive regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0050432 ! catecholamine secretion
relationship: positively_regulates GO:0050432 ! catecholamine secretion

[Term]
id: GO:0033673
name: negative regulation of kinase activity
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "down regulation of kinase activity" EXACT []
synonym: "down-regulation of kinase activity" EXACT []
synonym: "downregulation of kinase activity" EXACT []
synonym: "inhibition of kinase activity" NARROW []
synonym: "kinase inhibitor" NARROW []
is_a: GO:0042326 ! negative regulation of phosphorylation
is_a: GO:0043549 ! regulation of kinase activity
is_a: GO:0051348 ! negative regulation of transferase activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0016301 ! kinase activity
relationship: negatively_regulates GO:0016301 ! kinase activity

[Term]
id: GO:0033674
name: positive regulation of kinase activity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "kinase activator" NARROW []
synonym: "stimulation of kinase activity" NARROW []
synonym: "up regulation of kinase activity" EXACT []
synonym: "up-regulation of kinase activity" EXACT []
synonym: "upregulation of kinase activity" EXACT []
is_a: GO:0042327 ! positive regulation of phosphorylation
is_a: GO:0043549 ! regulation of kinase activity
is_a: GO:0051347 ! positive regulation of transferase activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0016301 ! kinase activity
relationship: positively_regulates GO:0016301 ! kinase activity

[Term]
id: GO:0033750
name: ribosome localization
namespace: biological_process
alt_id: GO:0033753
def: "A process in which a ribosome is transported to, and/or maintained in, a specific location." [GOC:mah]
synonym: "establishment of ribosome localisation" RELATED []
synonym: "establishment of ribosome localization" RELATED []
synonym: "ribosome localisation" RELATED []
is_a: GO:0051640 ! organelle localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0005840 ! ribosome
relationship: has_primary_input GO:0005840 ! ribosome

[Term]
id: GO:0033762
name: response to glucagon
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." [GOC:sl]
synonym: "response to glucagon stimulus" EXACT [GOC:dos]
is_a: GO:0043434 ! response to peptide hormone
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:5391 ! glucagon
relationship: has_primary_input CHEBI:5391 ! glucagon

[Term]
id: GO:0033993
name: response to lipid
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." [GOC:sl]
is_a: GO:0010033 ! response to organic substance
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:18059 ! lipid
relationship: has_primary_input CHEBI:18059 ! lipid

[Term]
id: GO:0034067
name: protein localization to Golgi apparatus
namespace: biological_process
alt_id: GO:0000042
alt_id: GO:0072600
def: "A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus." [GOC:mah]
synonym: "establishment of protein localisation to Golgi" NARROW [GOC:mah]
synonym: "establishment of protein localization in Golgi" NARROW []
synonym: "establishment of protein localization to Golgi" NARROW []
synonym: "establishment of protein localization to Golgi apparatus" NARROW [GOC:mah]
synonym: "protein localisation in Golgi apparatus" EXACT [GOC:mah]
synonym: "protein localization in Golgi apparatus" EXACT []
synonym: "protein targeting to Golgi" RELATED []
synonym: "protein-Golgi targeting" RELATED []
is_a: GO:0033365 ! protein localization to organelle
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005794 ! Golgi apparatus
relationship: has_target_end_location GO:0005794 ! Golgi apparatus
created_by: mah
creation_date: 2011-02-14T02:26:36Z

[Term]
id: GO:0034101
name: erythrocyte homeostasis
namespace: biological_process
def: "Any process of regulating the production and elimination of erythrocytes within an organism." [GOC:add, PMID:10694114, PMID:14754397]
synonym: "RBC homeostasis" EXACT [CL:0000232]
synonym: "red blood cell homeostasis" EXACT [CL:0000232]
is_a: GO:0002262 ! myeloid cell homeostasis
intersection_of: GO:0048872 ! homeostasis of number of cells
intersection_of: acts_on_population_of CL:0000232 ! erythrocyte
relationship: acts_on_population_of CL:0000232 ! erythrocyte

[Term]
id: GO:0034219
name: carbohydrate transmembrane transport
namespace: biological_process
def: "The process in which a carbohydrate is transported across a membrane." [GOC:mah]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "carbohydrate membrane transport" EXACT []
synonym: "transmembrane carbohydrate transport" EXACT [GOC:dph, GOC:tb]
is_a: GO:0008643 ! carbohydrate transport
is_a: GO:0055085 ! transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:16646 ! carbohydrate
intersection_of: results_in_transport_across GO:0016020 ! membrane

[Term]
id: GO:0034220
name: monoatomic ion transmembrane transport
namespace: biological_process
alt_id: GO:0099131
def: "A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:mah]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "ATP hydrolysis coupled ion transmembrane transport" NARROW []
synonym: "ion membrane transport" EXACT []
synonym: "ion transmembrane transport" BROAD []
synonym: "transmembrane ion transport" EXACT [GOC:dph, GOC:tb]
is_a: GO:0006811 ! monoatomic ion transport
is_a: GO:0055085 ! transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion
intersection_of: results_in_transport_across GO:0016020 ! membrane

[Term]
id: GO:0034242
name: negative regulation of syncytium formation by plasma membrane fusion
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mah]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051129 ! negative regulation of cellular component organization
is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion
relationship: negatively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion

[Term]
id: GO:0034248
name: regulation of amide metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah]
synonym: "regulation of amide metabolism" EXACT []
synonym: "regulation of cellular amide metabolic process" EXACT []
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0043603 ! amide metabolic process
relationship: regulates GO:0043603 ! amide metabolic process

[Term]
id: GO:0034249
name: negative regulation of amide metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah]
synonym: "negative regulation of amide metabolism" EXACT []
synonym: "negative regulation of cellular amide metabolic process" EXACT []
is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0043603 ! amide metabolic process
relationship: negatively_regulates GO:0043603 ! amide metabolic process

[Term]
id: GO:0034250
name: positive regulation of amide metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah]
synonym: "positive regulation of amide metabolism" EXACT []
synonym: "positive regulation of cellular amide metabolic process" EXACT []
is_a: GO:0034248 ! regulation of amide metabolic process
is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0043603 ! amide metabolic process
relationship: positively_regulates GO:0043603 ! amide metabolic process

[Term]
id: GO:0034251
name: regulation of amide catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah]
synonym: "regulation of amide breakdown" EXACT []
synonym: "regulation of amide catabolism" EXACT []
synonym: "regulation of amide degradation" EXACT []
synonym: "regulation of cellular amide catabolic process" EXACT []
is_a: GO:0009894 ! regulation of catabolic process
is_a: GO:0034248 ! regulation of amide metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0043605 ! amide catabolic process
relationship: regulates GO:0043605 ! amide catabolic process

[Term]
id: GO:0034252
name: negative regulation of amide catabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah]
synonym: "negative regulation of amide breakdown" EXACT []
synonym: "negative regulation of amide catabolism" EXACT []
synonym: "negative regulation of amide degradation" RELATED []
synonym: "negative regulation of cellular amide catabolic process" EXACT []
is_a: GO:0009895 ! negative regulation of catabolic process
is_a: GO:0034249 ! negative regulation of amide metabolic process
is_a: GO:0034251 ! regulation of amide catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0043605 ! amide catabolic process
relationship: negatively_regulates GO:0043605 ! amide catabolic process

[Term]
id: GO:0034253
name: positive regulation of amide catabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah]
synonym: "positive regulation of amide breakdown" EXACT []
synonym: "positive regulation of amide catabolism" EXACT []
synonym: "positive regulation of amide degradation" RELATED []
synonym: "positive regulation of cellular amide catabolic process" EXACT []
is_a: GO:0009896 ! positive regulation of catabolic process
is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0034251 ! regulation of amide catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0043605 ! amide catabolic process
relationship: positively_regulates GO:0043605 ! amide catabolic process

[Term]
id: GO:0034284
name: response to monosaccharide
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." [GOC:mah]
synonym: "response to monosaccharide stimulus" EXACT [GOC:dos]
is_a: GO:0009743 ! response to carbohydrate
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:35381 ! monosaccharide
relationship: has_primary_input CHEBI:35381 ! monosaccharide

[Term]
id: GO:0034329
name: cell junction assembly
namespace: biological_process
def: "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction." [GOC:mah]
is_a: GO:0022607 ! cellular component assembly
is_a: GO:0034330 ! cell junction organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0030054 ! cell junction
relationship: results_in_assembly_of GO:0030054 ! cell junction

[Term]
id: GO:0034330
name: cell junction organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." [GOC:dph, GOC:jl, GOC:mah]
subset: goslim_chembl
subset: goslim_generic
synonym: "cell junction assembly and maintenance" EXACT []
synonym: "cell junction biogenesis" RELATED []
synonym: "cell junction organisation" EXACT [GOC:mah]
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0030054 ! cell junction
relationship: results_in_organization_of GO:0030054 ! cell junction

[Term]
id: GO:0034349
name: glial cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system." [CL:0000125, GOC:mtg_apoptosis, GOC:sart]
synonym: "apoptosis of glia" EXACT []
synonym: "apoptosis of glial cells" EXACT []
synonym: "glia apoptosis" EXACT []
synonym: "glia programmed cell death by apoptosis" EXACT []
synonym: "glial cell apoptosis" NARROW []
synonym: "glial cell programmed cell death by apoptosis" EXACT []
synonym: "programmed cell death of glia by apoptosis" EXACT []
synonym: "programmed cell death of glial cells by apoptosis" EXACT []
synonym: "programmed cell death, glia" EXACT []
synonym: "programmed cell death, glial cells" EXACT []
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000125 ! glial cell
relationship: occurs_in CL:0000125 ! glial cell

[Term]
id: GO:0034350
name: regulation of glial cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis]
synonym: "regulation of glial cell apoptosis" RELATED []
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0034349 ! glial cell apoptotic process
relationship: regulates GO:0034349 ! glial cell apoptotic process

[Term]
id: GO:0034351
name: negative regulation of glial cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis]
synonym: "down regulation of glial cell apoptosis" EXACT []
synonym: "down-regulation of glial cell apoptosis" EXACT []
synonym: "downregulation of glial cell apoptosis" EXACT []
synonym: "inhibition of glial cell apoptosis" NARROW []
synonym: "negative regulation of glial cell apoptosis" NARROW []
is_a: GO:0034350 ! regulation of glial cell apoptotic process
is_a: GO:0043066 ! negative regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0034349 ! glial cell apoptotic process
relationship: negatively_regulates GO:0034349 ! glial cell apoptotic process

[Term]
id: GO:0034352
name: positive regulation of glial cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis]
synonym: "activation of glial cell apoptosis" NARROW []
synonym: "positive regulation of glial cell apoptosis" NARROW []
synonym: "stimulation of glial cell apoptosis" NARROW []
synonym: "up regulation of glial cell apoptosis" EXACT []
synonym: "up-regulation of glial cell apoptosis" EXACT []
synonym: "upregulation of glial cell apoptosis" EXACT []
is_a: GO:0034350 ! regulation of glial cell apoptotic process
is_a: GO:0043065 ! positive regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0034349 ! glial cell apoptotic process
relationship: positively_regulates GO:0034349 ! glial cell apoptotic process

[Term]
id: GO:0034390
name: smooth muscle cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels." [CL:0000192, GOC:BHF, GOC:mah, GOC:mtg_apoptosis, GOC:rl]
synonym: "apoptosis of smooth muscle cells" EXACT []
synonym: "programmed cell death of smooth muscle cells by apoptosis" EXACT []
synonym: "programmed cell death, smooth muscle cells" EXACT []
synonym: "SMC apoptosis" EXACT []
synonym: "smooth muscle cell apoptosis" NARROW []
synonym: "smooth muscle cell programmed cell death by apoptosis" EXACT []
is_a: GO:0010657 ! muscle cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000192 ! smooth muscle cell
relationship: occurs_in CL:0000192 ! smooth muscle cell

[Term]
id: GO:0034391
name: regulation of smooth muscle cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl]
synonym: "regulation of SMC apoptosis" EXACT []
synonym: "regulation of smooth muscle cell apoptosis" NARROW []
is_a: GO:0010660 ! regulation of muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0034390 ! smooth muscle cell apoptotic process
relationship: regulates GO:0034390 ! smooth muscle cell apoptotic process

[Term]
id: GO:0034392
name: negative regulation of smooth muscle cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl]
synonym: "down regulation of smooth muscle cell apoptosis" EXACT []
synonym: "down-regulation of smooth muscle cell apoptosis" EXACT []
synonym: "downregulation of smooth muscle cell apoptosis" EXACT []
synonym: "inhibition of smooth muscle cell apoptosis" NARROW []
synonym: "negative regulation of SMC apoptosis" EXACT []
synonym: "negative regulation of smooth muscle cell apoptosis" NARROW []
is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process
is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0034390 ! smooth muscle cell apoptotic process
relationship: negatively_regulates GO:0034390 ! smooth muscle cell apoptotic process

[Term]
id: GO:0034393
name: positive regulation of smooth muscle cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl]
synonym: "activation of smooth muscle cell apoptosis" NARROW []
synonym: "positive regulation of SMC apoptosis" EXACT []
synonym: "positive regulation of smooth muscle cell apoptosis" NARROW []
synonym: "stimulation of smooth muscle cell apoptosis" NARROW []
synonym: "up regulation of smooth muscle cell apoptosis" EXACT []
synonym: "up-regulation of smooth muscle cell apoptosis" EXACT []
synonym: "upregulation of smooth muscle cell apoptosis" EXACT []
is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process
is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0034390 ! smooth muscle cell apoptotic process
relationship: positively_regulates GO:0034390 ! smooth muscle cell apoptotic process

[Term]
id: GO:0034436
name: glycoprotein transport
namespace: biological_process
def: "The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah, GOC:rl]
is_a: GO:0045184 ! establishment of protein localization
is_a: GO:1901264 ! carbohydrate derivative transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:17089 ! glycoprotein
relationship: has_primary_input CHEBI:17089 ! glycoprotein

[Term]
id: GO:0034486
name: vacuolar transmembrane transport
namespace: biological_process
def: "The process in which a solute is transported from one side of the vacuolar membrane to the other." [GOC:mah]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "vacuolar membrane transport" EXACT []
is_a: GO:0055085 ! transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: results_in_transport_across GO:0016020 ! membrane
intersection_of: results_in_transport_to_from_or_in GO:0005773 ! vacuole
relationship: results_in_transport_to_from_or_in GO:0005773 ! vacuole

[Term]
id: GO:0034487
name: vacuolar amino acid transmembrane transport
namespace: biological_process
def: "The process in which an amino acid is transported from one side of the vacuolar membrane to the other." [GOC:mah]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "vacuolar amino acid membrane transport" EXACT []
is_a: GO:0003333 ! amino acid transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:33709 ! amino acid
intersection_of: results_in_transport_across GO:0005774 ! vacuolar membrane
relationship: results_in_transport_across GO:0005774 ! vacuolar membrane

[Term]
id: GO:0034502
name: protein localization to chromosome
namespace: biological_process
def: "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome." [GOC:mah]
synonym: "condensin localization to chromosome" NARROW []
synonym: "protein localisation to chromosome" EXACT [GOC:mah]
is_a: GO:0033365 ! protein localization to organelle
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005694 ! chromosome
relationship: has_target_end_location GO:0005694 ! chromosome

[Term]
id: GO:0034504
name: protein localization to nucleus
namespace: biological_process
alt_id: GO:0044744
def: "A process in which a protein transports or maintains the localization of another protein to the nucleus." [GOC:ecd]
synonym: "protein localisation to nucleus" EXACT [GOC:mah]
synonym: "protein localization in cell nucleus" EXACT []
synonym: "protein localization in nucleus" EXACT [GOC:mah]
synonym: "protein targeting to nucleus" RELATED []
is_a: GO:0033365 ! protein localization to organelle
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005634 ! nucleus
relationship: has_target_end_location GO:0005634 ! nucleus
creation_date: 2012-11-07T15:45:54Z

[Term]
id: GO:0034641
name: cellular nitrogen compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah]
subset: gocheck_do_not_annotate
subset: goslim_chembl
synonym: "cellular nitrogen compound metabolism" EXACT []
is_a: GO:0006807 ! nitrogen compound metabolic process
is_a: GO:0044237 ! cellular metabolic process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI

[Term]
id: GO:0034654
name: nucleobase-containing compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah]
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid anabolism" EXACT []
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis" EXACT []
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid formation" EXACT []
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid synthesis" NARROW []
is_a: GO:0006139 ! nucleobase-containing compound metabolic process
is_a: GO:0018130 ! heterocycle biosynthetic process
is_a: GO:0019438 ! aromatic compound biosynthetic process
is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process
is_a: GO:1901362 ! organic cyclic compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:61120 ! nucleobase-containing molecular entity
relationship: has_primary_output CHEBI:61120 ! nucleobase-containing molecular entity

[Term]
id: GO:0034655
name: nucleobase-containing compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah]
subset: goslim_chembl
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid breakdown" EXACT []
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolic process" RELATED [GOC:dph, GOC:tb]
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolism" EXACT []
synonym: "nucleobase, nucleoside, nucleotide and nucleic acid degradation" EXACT []
is_a: GO:0006139 ! nucleobase-containing compound metabolic process
is_a: GO:0019439 ! aromatic compound catabolic process
is_a: GO:0044270 ! cellular nitrogen compound catabolic process
is_a: GO:0046700 ! heterocycle catabolic process
is_a: GO:1901361 ! organic cyclic compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity
relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity

[Term]
id: GO:0034672
name: anterior/posterior pattern specification involved in pronephros development
namespace: biological_process
def: "The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mah]
synonym: "anterior/posterior pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0039017 ! pattern specification involved in pronephros development
is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development
intersection_of: GO:0009952 ! anterior/posterior pattern specification
intersection_of: part_of GO:0048793 ! pronephros development

[Term]
id: GO:0034762
name: regulation of transmembrane transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah]
synonym: "regulation of membrane transport" EXACT []
is_a: GO:0050794 ! regulation of cellular process
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0055085 ! transmembrane transport
relationship: regulates GO:0055085 ! transmembrane transport

[Term]
id: GO:0034763
name: negative regulation of transmembrane transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah]
synonym: "down regulation of transmembrane transport" EXACT []
synonym: "down-regulation of transmembrane transport" EXACT []
synonym: "downregulation of transmembrane transport" EXACT []
synonym: "inhibition of transmembrane transport" NARROW []
synonym: "negative regulation of membrane transport" EXACT []
is_a: GO:0034762 ! regulation of transmembrane transport
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051051 ! negative regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0055085 ! transmembrane transport
relationship: negatively_regulates GO:0055085 ! transmembrane transport

[Term]
id: GO:0034764
name: positive regulation of transmembrane transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah]
synonym: "activation of transmembrane transport" NARROW []
synonym: "positive regulation of membrane transport" EXACT []
synonym: "stimulation of transmembrane transport" NARROW []
synonym: "up regulation of transmembrane transport" EXACT []
synonym: "up-regulation of transmembrane transport" EXACT []
synonym: "upregulation of transmembrane transport" EXACT []
is_a: GO:0034762 ! regulation of transmembrane transport
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051050 ! positive regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0055085 ! transmembrane transport
relationship: positively_regulates GO:0055085 ! transmembrane transport

[Term]
id: GO:0034765
name: regulation of monoatomic ion transmembrane transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah]
synonym: "regulation of ion membrane transport" EXACT []
synonym: "regulation of ion transmembrane transport" BROAD []
synonym: "regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb]
is_a: GO:0034762 ! regulation of transmembrane transport
is_a: GO:0043269 ! regulation of monoatomic ion transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0034220 ! monoatomic ion transmembrane transport
relationship: regulates GO:0034220 ! monoatomic ion transmembrane transport

[Term]
id: GO:0034766
name: negative regulation of monoatomic ion transmembrane transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah]
synonym: "down regulation of transmembrane ion transport" EXACT []
synonym: "down-regulation of transmembrane ion transport" EXACT []
synonym: "downregulation of transmembrane ion transport" EXACT []
synonym: "inhibition of transmembrane ion transport" NARROW []
synonym: "negative regulation of ion membrane transport" EXACT []
synonym: "negative regulation of ion transmembrane transport" BROAD []
synonym: "negative regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb]
is_a: GO:0034763 ! negative regulation of transmembrane transport
is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport
is_a: GO:0043271 ! negative regulation of monoatomic ion transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0034220 ! monoatomic ion transmembrane transport
relationship: negatively_regulates GO:0034220 ! monoatomic ion transmembrane transport

[Term]
id: GO:0034767
name: positive regulation of monoatomic ion transmembrane transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah]
synonym: "activation of transmembrane ion transport" NARROW []
synonym: "positive regulation of ion membrane transport" EXACT []
synonym: "positive regulation of ion transmembrane transport" BROAD []
synonym: "positive regulation of transmembrane ion transport" EXACT []
synonym: "stimulation of transmembrane ion transport" NARROW []
synonym: "up regulation of transmembrane ion transport" EXACT []
synonym: "up-regulation of transmembrane ion transport" EXACT []
synonym: "upregulation of transmembrane ion transport" EXACT []
is_a: GO:0034764 ! positive regulation of transmembrane transport
is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport
is_a: GO:0043270 ! positive regulation of monoatomic ion transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0034220 ! monoatomic ion transmembrane transport
relationship: positively_regulates GO:0034220 ! monoatomic ion transmembrane transport

[Term]
id: GO:0034769
name: basement membrane disassembly
namespace: biological_process
alt_id: GO:0060881
def: "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion." [GOC:sart, PMID:17301221]
comment: Note that this term has no relationship to 'membrane disassembly ; GO:0030397' because the basement membrane is not a lipid bilayer.
synonym: "basal lamina disassembly" RELATED []
is_a: GO:0022617 ! extracellular matrix disassembly
is_a: GO:0071711 ! basement membrane organization
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0005604 ! basement membrane
relationship: results_in_disassembly_of GO:0005604 ! basement membrane
created_by: dph
creation_date: 2009-08-13T11:27:24Z

[Term]
id: GO:0035019
name: somatic stem cell population maintenance
namespace: biological_process
def: "Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line." [GOC:bf, ISBN:0582227089]
is_a: GO:0019827 ! stem cell population maintenance
intersection_of: GO:0098727 ! maintenance of cell number
intersection_of: acts_on_population_of CL:0000723 ! somatic stem cell
relationship: acts_on_population_of CL:0000723 ! somatic stem cell

[Term]
id: GO:0035039
name: male pronucleus assembly
namespace: biological_process
def: "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division." [GOC:bf, PMID:11735001]
synonym: "male pronucleus formation" RELATED [GOC:dph]
is_a: GO:0006997 ! nucleus organization
is_a: GO:0022414 ! reproductive process
is_a: GO:0070925 ! organelle assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0001940 ! male pronucleus
relationship: part_of GO:0007338 ! single fertilization
relationship: results_in_assembly_of GO:0001940 ! male pronucleus

[Term]
id: GO:0035040
name: sperm nuclear envelope removal
namespace: biological_process
def: "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus." [GOC:bf, PMID:11735001]
is_a: GO:0022414 ! reproductive process
is_a: GO:0051081 ! nuclear membrane disassembly
intersection_of: GO:0051081 ! nuclear membrane disassembly
intersection_of: occurs_in CL:0000019 ! sperm
relationship: occurs_in CL:0000019 ! sperm
relationship: part_of GO:0035039 ! male pronucleus assembly

[Term]
id: GO:0035045
name: sperm plasma membrane disassembly
namespace: biological_process
def: "The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg." [GOC:bf, ISBN:0879694238]
synonym: "sperm plasma membrane breakdown" EXACT []
synonym: "sperm plasma membrane catabolism" EXACT []
synonym: "sperm plasma membrane degradation" EXACT []
is_a: GO:0007009 ! plasma membrane organization
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0030397 ! membrane disassembly
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0097524 ! sperm plasma membrane
relationship: part_of GO:0007338 ! single fertilization
relationship: results_in_disassembly_of GO:0097524 ! sperm plasma membrane

[Term]
id: GO:0035050
name: embryonic heart tube development
namespace: biological_process
def: "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field." [GOC:go_curators]
is_a: GO:0035295 ! tube development
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004141 ! heart tube
relationship: part_of GO:0007507 ! heart development
relationship: part_of GO:0048568 ! embryonic organ development
relationship: results_in_development_of UBERON:0004141 ! heart tube

[Term]
id: GO:0035051
name: cardiocyte differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual." [GOC:bf]
synonym: "cardiac cell differentiation" EXACT []
synonym: "heart cell differentiation" EXACT []
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002494 ! cardiocyte
relationship: part_of GO:0007507 ! heart development
relationship: results_in_acquisition_of_features_of CL:0002494 ! cardiocyte

[Term]
id: GO:0035082
name: axoneme assembly
namespace: biological_process
alt_id: GO:0035083
alt_id: GO:0035084
def: "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, GOC:jl, ISBN:0815316194]
comment: Note that cilia and eukaryotic flagella are deemed to be equivalent.
synonym: "axoneme biogenesis" RELATED [GOC:mah]
synonym: "ciliary axoneme assembly" EXACT []
synonym: "cilium axoneme assembly" EXACT []
synonym: "cilium axoneme biogenesis" RELATED [GOC:mah]
synonym: "flagellar axoneme assembly" EXACT []
synonym: "flagellum axoneme assembly" EXACT []
is_a: GO:0001578 ! microtubule bundle formation
is_a: GO:0022607 ! cellular component assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0005930 ! axoneme
relationship: part_of GO:0060271 ! cilium assembly
relationship: results_in_assembly_of GO:0005930 ! axoneme

[Term]
id: GO:0035107
name: appendage morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000026 ! appendage
relationship: part_of GO:0048736 ! appendage development
relationship: results_in_morphogenesis_of UBERON:0000026 ! appendage

[Term]
id: GO:0035112
name: genitalia morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal." [GOC:bf]
synonym: "genital morphogenesis" RELATED []
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000990 ! reproductive system
relationship: part_of GO:0048806 ! genitalia development
relationship: results_in_morphogenesis_of UBERON:0000990 ! reproductive system

[Term]
id: GO:0035148
name: tube formation
namespace: biological_process
def: "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow." [GOC:bf]
synonym: "lumen formation in an anatomical structure" RELATED [GOC:dph, GOC:mah]
synonym: "tube lumen formation" EXACT [GOC:dph, GOC:mah]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000025 ! tube
relationship: part_of GO:0035239 ! tube morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0000025 ! tube

[Term]
id: GO:0035190
name: syncytial nuclear migration
namespace: biological_process
def: "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex." [GOC:bf, ISBN:0879694238, PMID:8314839]
is_a: GO:0007097 ! nuclear migration
intersection_of: GO:0007097 ! nuclear migration
intersection_of: occurs_in CL:0000228 ! multinucleate cell
relationship: occurs_in CL:0000228 ! multinucleate cell
relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm

[Term]
id: GO:0035234
name: ectopic germ cell programmed cell death
namespace: biological_process
def: "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo." [PMID:12814944]
synonym: "programmed cell death of ectopic germ cells" EXACT []
synonym: "programmed cell death, ectopic germ cells" EXACT []
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0010623 ! programmed cell death involved in cell development
intersection_of: GO:0012501 ! programmed cell death
intersection_of: occurs_in CL:0000586 ! germ cell
relationship: occurs_in CL:0000586 ! germ cell

[Term]
id: GO:0035239
name: tube morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:bf, PMID:14624839]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000025 ! tube
relationship: part_of GO:0035295 ! tube development
relationship: results_in_morphogenesis_of UBERON:0000025 ! tube

[Term]
id: GO:0035260
name: internal genitalia morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [http://www.ndif.org/Terms/genitalia.html]
is_a: GO:0035112 ! genitalia morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004175 ! internal genitalia
relationship: results_in_morphogenesis_of UBERON:0004175 ! internal genitalia

[Term]
id: GO:0035261
name: external genitalia morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals." [http://www.ndif.org/Terms/genitalia.html]
is_a: GO:0035112 ! genitalia morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004176 ! external genitalia
relationship: results_in_morphogenesis_of UBERON:0004176 ! external genitalia

[Term]
id: GO:0035262
name: gonad morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals." [ISBN:0198612001]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000991 ! gonad
relationship: part_of GO:0008406 ! gonad development
relationship: results_in_morphogenesis_of UBERON:0000991 ! gonad

[Term]
id: GO:0035264
name: multicellular organism growth
namespace: biological_process
def: "The increase in size or mass of an entire multicellular organism, as opposed to cell growth." [GOC:bf, GOC:curators, GOC:dph, GOC:tb]
synonym: "body growth" RELATED []
is_a: GO:0032501 ! multicellular organismal process
is_a: GO:0048589 ! developmental growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: results_in_growth_of UBERON:0000468 ! multicellular organism
relationship: results_in_growth_of UBERON:0000468 ! multicellular organism

[Term]
id: GO:0035265
name: organ growth
namespace: biological_process
def: "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function." [GOC:bf, ISBN:0471245208, ISBN:0721662544]
is_a: GO:0032501 ! multicellular organismal process
is_a: GO:0048589 ! developmental growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: results_in_growth_of UBERON:0000062 ! organ
relationship: results_in_growth_of UBERON:0000062 ! organ

[Term]
id: GO:0035270
name: endocrine system development
namespace: biological_process
def: "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes." [GOC:bf, Wikipedia:Development_of_the_endocrine_system]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000949 ! endocrine system
relationship: results_in_development_of UBERON:0000949 ! endocrine system

[Term]
id: GO:0035272
name: exocrine system development
namespace: biological_process
def: "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system." [GOC:bf, Wikipedia:Exocrine_gland]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002330 ! exocrine system
relationship: results_in_development_of UBERON:0002330 ! exocrine system

[Term]
id: GO:0035282
name: segmentation
namespace: biological_process
def: "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis." [PMID:10611687, PMID:9706689]
xref: Wikipedia:Segmentation_(biology)
is_a: GO:0003002 ! regionalization

[Term]
id: GO:0035290
name: trunk segmentation
namespace: biological_process
def: "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8." [PMID:1360402]
is_a: GO:0035282 ! segmentation
relationship: part_of GO:0007350 ! blastoderm segmentation

[Term]
id: GO:0035295
name: tube development
namespace: biological_process
def: "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." [PMID:12526790]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000025 ! tube
relationship: part_of GO:0007275 ! multicellular organism development
relationship: results_in_development_of UBERON:0000025 ! tube

[Term]
id: GO:0035372
name: protein localization to microtubule
namespace: biological_process
def: "A process in which a protein is transported to, or maintained at, a microtubule." [GOC:bf, GOC:lb]
synonym: "protein localisation to microtubule" EXACT [GOC:mah]
is_a: GO:0072698 ! protein localization to microtubule cytoskeleton
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005874 ! microtubule
relationship: has_target_end_location GO:0005874 ! microtubule
created_by: bf
creation_date: 2010-03-11T11:00:56Z

[Term]
id: GO:0035418
name: protein localization to synapse
namespace: biological_process
def: "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:bf]
synonym: "protein localisation to synapse" EXACT [GOC:mah]
is_a: GO:1902414 ! protein localization to cell junction
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0045202 ! synapse
relationship: has_target_end_location GO:0045202 ! synapse
created_by: bf
creation_date: 2010-03-29T10:58:53Z

[Term]
id: GO:0035433
name: acetate transmembrane transport
namespace: biological_process
def: "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:vw]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "acetate membrane transport" EXACT []
is_a: GO:0006846 ! acetate transport
is_a: GO:1905039 ! carboxylic acid transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:30089 ! acetate
intersection_of: results_in_transport_across GO:0016020 ! membrane
created_by: bf
creation_date: 2010-04-08T10:59:01Z

[Term]
id: GO:0035435
name: phosphate ion transmembrane transport
namespace: biological_process
def: "The process in which a phosphate is transported across a membrane." [GOC:vw]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "phosphate ion membrane transport" EXACT []
is_a: GO:0006817 ! phosphate ion transport
is_a: GO:0098661 ! inorganic anion transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:35780 ! phosphate ion
intersection_of: results_in_transport_across GO:0016020 ! membrane
created_by: bf
creation_date: 2010-04-08T11:24:06Z

[Term]
id: GO:0035441
name: cell migration involved in vasculogenesis
namespace: biological_process
def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes." [GOC:dgh]
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: part_of GO:0001570 ! vasculogenesis
relationship: part_of GO:0001570 ! vasculogenesis
created_by: bf
creation_date: 2010-04-09T03:53:01Z

[Term]
id: GO:0035556
name: intracellular signal transduction
namespace: biological_process
alt_id: GO:0007242
alt_id: GO:0007243
alt_id: GO:0023013
alt_id: GO:0023034
def: "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782]
subset: goslim_drosophila
synonym: "intracellular signal transduction pathway" NARROW []
synonym: "intracellular signaling cascade" RELATED [GOC:signaling]
synonym: "intracellular signaling pathway" RELATED []
synonym: "signal transmission via intracellular cascade" NARROW []
is_a: GO:0007165 ! signal transduction
intersection_of: GO:0007165 ! signal transduction
intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure
relationship: occurs_in GO:0005622 ! intracellular anatomical structure
created_by: bf
creation_date: 2010-05-14T01:14:37Z

[Term]
id: GO:0035592
name: establishment of protein localization to extracellular region
namespace: biological_process
def: "The directed movement of a protein to a specific location within the extracellular region." [GOC:bf, GOC:BHF]
synonym: "establishment of protein localisation in extracellular region" EXACT [GOC:mah]
synonym: "establishment of protein localization in extracellular region" EXACT []
is_a: GO:0045184 ! establishment of protein localization
intersection_of: GO:0045184 ! establishment of protein localization
intersection_of: has_target_end_location GO:0005576 ! extracellular region
relationship: has_target_end_location GO:0005576 ! extracellular region
created_by: bf
creation_date: 2010-11-09T10:25:08Z

[Term]
id: GO:0035622
name: intrahepatic bile duct development
namespace: biological_process
def: "The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver)." [GOC:bf, PMID:20614624]
synonym: "IHBD development" EXACT [PMID:20614624]
synonym: "intrahepatic biliary duct development" EXACT [PMID:20614624]
is_a: GO:0061009 ! common bile duct development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003704 ! intrahepatic bile duct
relationship: part_of GO:0001889 ! liver development
relationship: results_in_development_of UBERON:0003704 ! intrahepatic bile duct
created_by: bf
creation_date: 2010-12-08T04:10:50Z

[Term]
id: GO:0035628
name: cystic duct development
namespace: biological_process
def: "The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct." [PMID:20614624]
is_a: GO:0061009 ! common bile duct development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001152 ! cystic duct
relationship: results_in_development_of UBERON:0001152 ! cystic duct
created_by: bf
creation_date: 2010-12-10T01:24:28Z

[Term]
id: GO:0035645
name: enteric smooth muscle cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine." [CL:0002504, GOC:BHF]
synonym: "intestinal smooth muscle cell differentiation" EXACT [CL:0002504]
is_a: GO:0051145 ! smooth muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002504 ! enteric smooth muscle cell
relationship: part_of GO:0048565 ! digestive tract development
relationship: results_in_acquisition_of_features_of CL:0002504 ! enteric smooth muscle cell
created_by: bf
creation_date: 2011-01-21T02:58:58Z

[Term]
id: GO:0035701
name: hematopoietic stem cell migration
namespace: biological_process
def: "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." [CL:0000037, GOC:BHF, PMID:20234092]
synonym: "hemopoietic stem cell migration" EXACT [CL:0000037]
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000037 ! hematopoietic stem cell
relationship: results_in_movement_of CL:0000037 ! hematopoietic stem cell
created_by: bf
creation_date: 2011-02-28T03:20:36Z

[Term]
id: GO:0035725
name: sodium ion transmembrane transport
namespace: biological_process
def: "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:vw]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "sodium ion membrane transport" EXACT []
is_a: GO:0006814 ! sodium ion transport
is_a: GO:0098655 ! monoatomic cation transmembrane transport
is_a: GO:0098662 ! inorganic cation transmembrane transport
intersection_of: GO:0055085 ! transmembrane transport
intersection_of: has_primary_input CHEBI:29101 ! sodium(1+)
created_by: bf
creation_date: 2011-03-10T02:52:36Z

[Term]
id: GO:0035735
name: intraciliary transport involved in cilium assembly
namespace: biological_process
def: "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly." [GOC:bf, GOC:cilia, Reactome:R-HSA-5620924.2]
synonym: "intraciliary transport involved in cilium morphogenesis" RELATED []
synonym: "intraflagellar transport" BROAD []
synonym: "intraflagellar transport involved in cilium morphogenesis" RELATED []
xref: Reactome:R-HSA-5620924.2
is_a: GO:0042073 ! intraciliary transport
intersection_of: GO:0042073 ! intraciliary transport
intersection_of: part_of GO:0060271 ! cilium assembly
relationship: part_of GO:0060271 ! cilium assembly
created_by: bf
creation_date: 2011-03-17T10:55:42Z

[Term]
id: GO:0035736
name: cell proliferation involved in compound eye morphogenesis
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis." [GOC:bf, GOC:sart]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: part_of GO:0001745 ! compound eye morphogenesis
relationship: part_of GO:0001745 ! compound eye morphogenesis
created_by: bf
creation_date: 2011-03-17T10:57:03Z

[Term]
id: GO:0035778
name: pronephric nephron tubule epithelial cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069]
is_a: GO:0039014 ! cell differentiation involved in pronephros development
is_a: GO:0072160 ! nephron tubule epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000090 ! pronephric nephron tubule epithelial cell
relationship: part_of GO:0039020 ! pronephric nephron tubule development
relationship: results_in_acquisition_of_features_of CL:1000090 ! pronephric nephron tubule epithelial cell
created_by: bf
creation_date: 2011-04-04T11:07:47Z

[Term]
id: GO:0035779
name: angioblast cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)." [CL:0000566, GOC:yaf]
synonym: "angioblastic mesenchymal cell differentiation" EXACT [CL:0000566]
is_a: GO:0048863 ! stem cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000566 ! angioblastic mesenchymal cell
relationship: part_of GO:0001568 ! blood vessel development
relationship: results_in_acquisition_of_features_of CL:0000566 ! angioblastic mesenchymal cell
created_by: bf
creation_date: 2011-04-04T11:10:38Z

[Term]
id: GO:0035787
name: cell migration involved in kidney development
namespace: biological_process
def: "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf]
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: part_of GO:0001822 ! kidney development
relationship: part_of GO:0001822 ! kidney development
created_by: bf
creation_date: 2011-04-06T10:39:52Z

[Term]
id: GO:0035788
name: cell migration involved in metanephros development
namespace: biological_process
def: "The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf]
synonym: "cell migration involved in metanephric kidney development" EXACT [GOC:bf]
is_a: GO:0035787 ! cell migration involved in kidney development
intersection_of: GO:0016477 ! cell migration
intersection_of: part_of GO:0001656 ! metanephros development
relationship: part_of GO:0001656 ! metanephros development
created_by: bf
creation_date: 2011-04-06T10:42:21Z

[Term]
id: GO:0035799
name: ureter maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:17881463]
is_a: GO:0048799 ! animal organ maturation
intersection_of: GO:0071695 ! anatomical structure maturation
intersection_of: results_in_maturation_of UBERON:0000056 ! ureter
relationship: part_of GO:0072189 ! ureter development
relationship: results_in_maturation_of UBERON:0000056 ! ureter
created_by: bf
creation_date: 2011-04-14T01:13:39Z

[Term]
id: GO:0035805
name: egg coat
namespace: cellular_component
def: "A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." [PMID:16944418, PMID:17163408]
synonym: "vitelline membrane" NARROW [PMID:16944418, PMID:17163408]
synonym: "zona pellucida" NARROW [PMID:16944418, PMID:17163408]
is_a: GO:0031012 ! extracellular matrix
intersection_of: GO:0031012 ! extracellular matrix
intersection_of: part_of CL:0000025 ! egg cell
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of CL:0000025 ! egg cell
created_by: bf
creation_date: 2011-04-19T02:07:23Z

[Term]
id: GO:0035809
name: regulation of urine volume
namespace: biological_process
def: "Any process that modulates the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf]
synonym: "regulation of urinary volume" EXACT []
synonym: "regulation of urine flow" EXACT []
is_a: GO:0003014 ! renal system process
is_a: GO:0050878 ! regulation of body fluid levels
created_by: bf
creation_date: 2011-04-20T01:17:38Z

[Term]
id: GO:0035834
name: indole alkaloid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf]
synonym: "indole alkaloid metabolism" EXACT [GOC:bf]
is_a: GO:0009820 ! alkaloid metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:38958 ! indole alkaloid
relationship: has_primary_input_or_output CHEBI:38958 ! indole alkaloid
created_by: bf
creation_date: 2011-05-04T03:17:44Z

[Term]
id: GO:0035835
name: indole alkaloid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf]
synonym: "indole alkaloid anabolism" EXACT [GOC:bf]
synonym: "indole alkaloid biosynthesis" EXACT [GOC:bf]
synonym: "indole alkaloid formation" EXACT [GOC:bf]
synonym: "indole alkaloid synthesis" EXACT [GOC:bf]
is_a: GO:0009821 ! alkaloid biosynthetic process
is_a: GO:0035834 ! indole alkaloid metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:38958 ! indole alkaloid
relationship: has_primary_output CHEBI:38958 ! indole alkaloid
created_by: bf
creation_date: 2011-05-04T03:18:31Z

[Term]
id: GO:0035844
name: cloaca development
namespace: biological_process
def: "The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates." [GOC:dgh, ISBN:0582227089]
synonym: "cloacal development" EXACT [GOC:bf]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000162 ! cloaca
relationship: part_of GO:0001655 ! urogenital system development
relationship: part_of GO:0048546 ! digestive tract morphogenesis
relationship: results_in_development_of UBERON:0000162 ! cloaca
created_by: bf
creation_date: 2011-05-06T01:54:35Z

[Term]
id: GO:0035846
name: oviduct epithelium development
namespace: biological_process
def: "The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct." [GOC:yaf, http://www.thefreedictionary.com/oviduct]
synonym: "fallopian tube epithelium development" NARROW [GOC:yaf]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004804 ! oviduct epithelium
relationship: part_of GO:0060066 ! oviduct development
relationship: results_in_development_of UBERON:0004804 ! oviduct epithelium
created_by: bf
creation_date: 2011-05-10T10:53:05Z

[Term]
id: GO:0035847
name: uterine epithelium development
namespace: biological_process
def: "The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:bf, GOC:yaf]
synonym: "uterus epithelial development" EXACT [GOC:yaf]
is_a: GO:0035846 ! oviduct epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0006955 ! uterine epithelium
relationship: part_of GO:0060065 ! uterus development
relationship: results_in_development_of UBERON:0006955 ! uterine epithelium
created_by: bf
creation_date: 2011-05-10T10:57:45Z

[Term]
id: GO:0035848
name: oviduct morphogenesis
namespace: biological_process
def: "The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:yaf, http://www.thefreedictionary.com/oviduct]
synonym: "fallopian tube morphogenesis" NARROW [GOC:yaf]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0009887 ! animal organ morphogenesis
is_a: GO:0035239 ! tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000993 ! oviduct
relationship: part_of GO:0060066 ! oviduct development
relationship: results_in_morphogenesis_of UBERON:0000993 ! oviduct
created_by: bf
creation_date: 2011-05-10T11:01:20Z

[Term]
id: GO:0035850
name: epithelial cell differentiation involved in kidney development
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:16216236]
is_a: GO:0030855 ! epithelial cell differentiation
is_a: GO:0061005 ! cell differentiation involved in kidney development
intersection_of: GO:0030855 ! epithelial cell differentiation
intersection_of: part_of GO:0001822 ! kidney development
created_by: bf
creation_date: 2011-05-11T11:34:21Z

[Term]
id: GO:0035855
name: megakaryocyte development
namespace: biological_process
def: "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow." [CL:0000556, GOC:BHF, GOC:vk]
synonym: "megakaryocyte cell development" EXACT [GOC:bf]
is_a: GO:0061515 ! myeloid cell development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of CL:0000556 ! megakaryocyte
relationship: part_of GO:0030219 ! megakaryocyte differentiation
relationship: results_in_development_of CL:0000556 ! megakaryocyte
created_by: bf
creation_date: 2011-05-13T01:28:06Z

[Term]
id: GO:0035869
name: ciliary transition zone
namespace: cellular_component
def: "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm." [GOC:cilia, GOC:kmv, PMID:21422230]
comment: Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone.
synonym: "cilial transition zone" EXACT []
synonym: "cilium transition zone" EXACT []
synonym: "connecting cilium" RELATED []
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of GO:0005929 ! cilium
created_by: bf
creation_date: 2011-05-25T03:09:58Z

[Term]
id: GO:0035883
name: enteroendocrine cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system." [CL:0000164, GOC:bf]
is_a: GO:0002067 ! glandular epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000164 ! enteroendocrine cell
relationship: results_in_acquisition_of_features_of CL:0000164 ! enteroendocrine cell
created_by: bf
creation_date: 2011-06-06T11:48:51Z

[Term]
id: GO:0035886
name: vascular associated smooth muscle cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell." [GOC:sl, PMID:16151017, PMID:18267954]
synonym: "vascular smooth muscle cell differentiation" EXACT []
synonym: "VSMC differentiation" EXACT [PMID:16151017]
is_a: GO:0051145 ! smooth muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000359 ! vascular associated smooth muscle cell
relationship: part_of GO:0001944 ! vasculature development
relationship: results_in_acquisition_of_features_of CL:0000359 ! vascular associated smooth muscle cell
created_by: bf
creation_date: 2011-06-08T11:23:52Z

[Term]
id: GO:0035887
name: aortic smooth muscle cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta." [GOC:sl]
is_a: GO:0035886 ! vascular associated smooth muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002539 ! aortic smooth muscle cell
relationship: results_in_acquisition_of_features_of CL:0002539 ! aortic smooth muscle cell
created_by: bf
creation_date: 2011-06-08T11:34:26Z

[Term]
id: GO:0035904
name: aorta development
namespace: biological_process
def: "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta]
is_a: GO:0060840 ! artery development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000947 ! aorta
relationship: results_in_development_of UBERON:0000947 ! aorta
created_by: bf
creation_date: 2011-06-24T11:00:07Z

[Term]
id: GO:0035905
name: ascending aorta development
namespace: biological_process
def: "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001496 ! ascending aorta
relationship: part_of GO:0035904 ! aorta development
relationship: results_in_development_of UBERON:0001496 ! ascending aorta
created_by: bf
creation_date: 2011-06-24T11:02:01Z

[Term]
id: GO:0035906
name: descending aorta development
namespace: biological_process
def: "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001514 ! descending aorta
relationship: part_of GO:0035904 ! aorta development
relationship: results_in_development_of UBERON:0001514 ! descending aorta
created_by: bf
creation_date: 2011-06-24T11:05:22Z

[Term]
id: GO:0035907
name: dorsal aorta development
namespace: biological_process
def: "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014]
is_a: GO:0035904 ! aorta development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005805 ! dorsal aorta
relationship: results_in_development_of UBERON:0005805 ! dorsal aorta
created_by: bf
creation_date: 2011-06-24T11:07:01Z

[Term]
id: GO:0035909
name: aorta morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta]
is_a: GO:0048844 ! artery morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000947 ! aorta
relationship: part_of GO:0035904 ! aorta development
relationship: results_in_morphogenesis_of UBERON:0000947 ! aorta
created_by: bf
creation_date: 2011-06-24T11:11:11Z

[Term]
id: GO:0035910
name: ascending aorta morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001496 ! ascending aorta
relationship: part_of GO:0035905 ! ascending aorta development
relationship: part_of GO:0035909 ! aorta morphogenesis
relationship: results_in_morphogenesis_of UBERON:0001496 ! ascending aorta
created_by: bf
creation_date: 2011-06-24T11:14:52Z

[Term]
id: GO:0035911
name: descending aorta morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001514 ! descending aorta
relationship: part_of GO:0035906 ! descending aorta development
relationship: part_of GO:0035909 ! aorta morphogenesis
relationship: results_in_morphogenesis_of UBERON:0001514 ! descending aorta
created_by: bf
creation_date: 2011-06-24T11:19:24Z

[Term]
id: GO:0035912
name: dorsal aorta morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014]
is_a: GO:0035909 ! aorta morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005805 ! dorsal aorta
relationship: part_of GO:0035907 ! dorsal aorta development
relationship: results_in_morphogenesis_of UBERON:0005805 ! dorsal aorta
created_by: bf
creation_date: 2011-06-24T11:22:14Z

[Term]
id: GO:0035914
name: skeletal muscle cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle." [CL:0000188, GOC:BHF, GOC:vk]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000188 ! cell of skeletal muscle
relationship: part_of GO:0007519 ! skeletal muscle tissue development
relationship: results_in_acquisition_of_features_of CL:0000188 ! cell of skeletal muscle
created_by: bf
creation_date: 2011-06-24T02:36:19Z

[Term]
id: GO:0035929
name: steroid hormone secretion
namespace: biological_process
def: "The regulated release of any steroid that acts as a hormone into the circulatory system." [GOC:sl]
is_a: GO:0060986 ! endocrine hormone secretion
is_a: GO:0140353 ! lipid export from cell
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input CHEBI:26764 ! steroid hormone
relationship: has_primary_input CHEBI:26764 ! steroid hormone
created_by: bf
creation_date: 2011-07-20T01:01:00Z

[Term]
id: GO:0035935
name: androgen secretion
namespace: biological_process
def: "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates." [GOC:sl]
is_a: GO:0035929 ! steroid hormone secretion
created_by: bf
creation_date: 2011-07-20T01:11:31Z

[Term]
id: GO:0035987
name: endodermal cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo." [CL:0000223, GOC:yaf, PMID:17624332]
synonym: "endoderm cell differentiation" EXACT [CL:0000223]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000223 ! endodermal cell
relationship: part_of GO:0001706 ! endoderm formation
relationship: results_in_acquisition_of_features_of CL:0000223 ! endodermal cell
created_by: bf
creation_date: 2011-08-25T04:50:36Z

[Term]
id: GO:0035989
name: tendon development
namespace: biological_process
def: "The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force." [GOC:yaf, PMID:21412429, UBERON:0000043]
synonym: "sinew development" RELATED [UBERON:0000043]
is_a: GO:0061448 ! connective tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000043 ! tendon
relationship: results_in_development_of UBERON:0000043 ! tendon
created_by: bf
creation_date: 2011-08-26T04:14:30Z

[Term]
id: GO:0035992
name: tendon formation
namespace: biological_process
def: "The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts." [GOC:yaf, PMID:17567668, UBERON:0000043]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000043 ! tendon
relationship: part_of GO:0035989 ! tendon development
relationship: results_in_formation_of_anatomical_entity UBERON:0000043 ! tendon
created_by: bf
creation_date: 2011-08-30T01:35:10Z

[Term]
id: GO:0036072
name: direct ossification
namespace: biological_process
def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues." [GO_REF:0000034]
is_a: GO:0001503 ! ossification
created_by: bf
creation_date: 2011-12-19T01:47:22Z

[Term]
id: GO:0036093
name: germ cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population." [CL:0000586, GOC:kmv]
is_a: GO:0008283 ! cell population proliferation
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000586 ! germ cell
relationship: acts_on_population_of CL:0000586 ! germ cell
relationship: part_of GO:0007276 ! gamete generation
created_by: bf
creation_date: 2012-01-17T04:06:27Z

[Term]
id: GO:0036099
name: female germ-line stem cell population maintenance
namespace: biological_process
def: "The process by which an organism or tissue maintains a population of female germ-line stem cells." [GOC:sart]
is_a: GO:0030718 ! germ-line stem cell population maintenance
intersection_of: GO:0098727 ! maintenance of cell number
intersection_of: acts_on_population_of CL:0000022 ! female germ line stem cell
relationship: acts_on_population_of CL:0000022 ! female germ line stem cell
created_by: bf
creation_date: 2012-01-26T01:58:10Z

[Term]
id: GO:0036145
name: dendritic cell homeostasis
namespace: biological_process
def: "The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000451, GOC:uh, PMID:12570827, PMID:19176316]
synonym: "DC homeostasis" RELATED [PMID:19176316]
is_a: GO:0001776 ! leukocyte homeostasis
intersection_of: GO:0048872 ! homeostasis of number of cells
intersection_of: acts_on_population_of CL:0000451 ! dendritic cell
relationship: acts_on_population_of CL:0000451 ! dendritic cell
created_by: bf
creation_date: 2012-03-12T11:05:36Z

[Term]
id: GO:0036194
name: muscle cell projection
namespace: cellular_component
def: "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329]
synonym: "muscle arm" NARROW [GOC:kmv]
synonym: "myocyte projection" EXACT [CL:0000187]
synonym: "myopodia" NARROW [GOC:kmv]
is_a: GO:0120025 ! plasma membrane bounded cell projection
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: GO:0120025 ! plasma membrane bounded cell projection
intersection_of: part_of CL:0000187 ! muscle cell
relationship: part_of CL:0000187 ! muscle cell
created_by: bf
creation_date: 2012-04-20T10:20:47Z

[Term]
id: GO:0036195
name: muscle cell projection membrane
namespace: cellular_component
def: "The portion of the plasma membrane surrounding a muscle cell projection." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329]
is_a: GO:0031253 ! cell projection membrane
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: GO:0031253 ! cell projection membrane
intersection_of: part_of GO:0036194 ! muscle cell projection
relationship: part_of GO:0036194 ! muscle cell projection
created_by: bf
creation_date: 2012-04-20T10:21:51Z

[Term]
id: GO:0036293
name: response to decreased oxygen levels
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen." [GOC:al]
comment: This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'response to hypoxia ; GO:0001666'.
synonym: "response to lowered oxygen levels" EXACT [GOC:bf]
is_a: GO:0070482 ! response to oxygen levels
created_by: bf
creation_date: 2012-07-20T01:05:46Z

[Term]
id: GO:0036304
name: umbilical cord morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:gr, PMID:15107403]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002331 ! umbilical cord
relationship: part_of GO:0061027 ! umbilical cord development
relationship: results_in_morphogenesis_of UBERON:0002331 ! umbilical cord
created_by: bf
creation_date: 2012-08-08T10:12:11Z

[Term]
id: GO:0036333
name: hepatocyte homeostasis
namespace: biological_process
def: "Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules." [CL:0000182, GOC:nhn, PMID:19878874]
is_a: GO:0048872 ! homeostasis of number of cells
intersection_of: GO:0048872 ! homeostasis of number of cells
intersection_of: acts_on_population_of CL:0000182 ! hepatocyte
relationship: acts_on_population_of CL:0000182 ! hepatocyte
created_by: bf
creation_date: 2012-09-05T10:17:07Z

[Term]
id: GO:0036334
name: epidermal stem cell homeostasis
namespace: biological_process
def: "Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells." [CL:1000428, GOC:nhn, PMID:17666529]
is_a: GO:0048872 ! homeostasis of number of cells
intersection_of: GO:0048872 ! homeostasis of number of cells
intersection_of: acts_on_population_of CL:1000428 ! stem cell of epidermis
relationship: acts_on_population_of CL:1000428 ! stem cell of epidermis
created_by: bf
creation_date: 2012-09-05T10:21:23Z

[Term]
id: GO:0036336
name: dendritic cell migration
namespace: biological_process
def: "The movement of a dendritic cell within or between different tissues and organs of the body." [CL:0000451, GOC:nhn, PMID:19339990]
is_a: GO:0071674 ! mononuclear cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000451 ! dendritic cell
relationship: results_in_movement_of CL:0000451 ! dendritic cell
created_by: bf
creation_date: 2012-09-05T10:24:46Z

[Term]
id: GO:0036342
name: post-anal tail morphogenesis
namespace: biological_process
def: "The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance." [GOC:bf, GOC:kmv, Wikipedia:Chordate]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0007812 ! post-anal tail
relationship: in_taxon NCBITaxon:7711 {all_only="true"} ! Chordata
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
relationship: results_in_morphogenesis_of UBERON:0007812 ! post-anal tail
created_by: bf
creation_date: 2012-09-11T13:54:49Z

[Term]
id: GO:0036477
name: somatodendritic compartment
namespace: cellular_component
def: "The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon." [GOC:pad, GOC:PARL]
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of CL:0000540 ! neuron
created_by: bf
creation_date: 2014-07-24T10:06:19Z

[Term]
id: GO:0036484
name: trunk neural crest cell migration
namespace: biological_process
def: "The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo." [GOC:bf, GOC:mat, GOC:PARL, PMID:2387238]
synonym: "trunk NCC migration" EXACT [PMID:2387238]
is_a: GO:0001755 ! neural crest cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000011 ! migratory trunk neural crest cell
relationship: part_of GO:0035290 ! trunk segmentation
relationship: results_in_movement_of CL:0000011 ! migratory trunk neural crest cell
created_by: bf
creation_date: 2014-08-26T15:27:44Z

[Term]
id: GO:0036504
name: Golgi membrane fusion
namespace: biological_process
def: "The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane." [GOC:bf, GOC:PARL, PMID:12473691]
synonym: "Golgi apparatus membrane fusion" EXACT []
synonym: "membrane fusion involved in Golgi reassembly" EXACT [GOC:bf]
synonym: "post-mitotic fusion of Golgi membranes" EXACT [PMID:10811609]
is_a: GO:0090174 ! organelle membrane fusion
intersection_of: GO:0061025 ! membrane fusion
intersection_of: results_in_fusion_of GO:0000139 ! Golgi membrane
relationship: part_of GO:0090168 ! Golgi reassembly
relationship: results_in_fusion_of GO:0000139 ! Golgi membrane
created_by: bf
creation_date: 2015-05-21T10:05:06Z

[Term]
id: GO:0039006
name: pronephric nephron tubule formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros." [GOC:mtg_kidney_jan10]
synonym: "pronephric tubule formation" EXACT [GOC:mtg_kidney_jan10]
synonym: "pronephros tubule formation" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0072079 ! nephron tubule formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005310 ! pronephric nephron tubule
relationship: part_of GO:0039008 ! pronephric nephron tubule morphogenesis
relationship: part_of GO:0072116 ! pronephros formation
relationship: results_in_formation_of_anatomical_entity UBERON:0005310 ! pronephric nephron tubule
created_by: bf
creation_date: 2010-07-02T09:37:27Z

[Term]
id: GO:0039007
name: pronephric nephron morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072028 ! nephron morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005309 ! pronephric nephron
relationship: part_of GO:0039019 ! pronephric nephron development
relationship: part_of GO:0072114 ! pronephros morphogenesis
relationship: results_in_morphogenesis_of UBERON:0005309 ! pronephric nephron
created_by: bf
creation_date: 2010-07-02T09:38:53Z

[Term]
id: GO:0039008
name: pronephric nephron tubule morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron." [GOC:mtg_kidney_jan10, ZFA:00001558]
is_a: GO:0072078 ! nephron tubule morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005310 ! pronephric nephron tubule
relationship: part_of GO:0039007 ! pronephric nephron morphogenesis
relationship: part_of GO:0039020 ! pronephric nephron tubule development
relationship: results_in_morphogenesis_of UBERON:0005310 ! pronephric nephron tubule
created_by: bf
creation_date: 2010-07-02T09:45:55Z

[Term]
id: GO:0039014
name: cell differentiation involved in pronephros development
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]
synonym: "cell differentiation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0061005 ! cell differentiation involved in kidney development
intersection_of: GO:0030154 ! cell differentiation
intersection_of: part_of GO:0048793 ! pronephros development
relationship: part_of GO:0048793 ! pronephros development
created_by: bf
creation_date: 2010-07-02T09:59:25Z

[Term]
id: GO:0039015
name: cell proliferation involved in pronephros development
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros." [GOC:mtg_kidney_jan10]
synonym: "cell proliferation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0072111 ! cell proliferation involved in kidney development
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: part_of GO:0048793 ! pronephros development
relationship: part_of GO:0048793 ! pronephros development
created_by: bf
creation_date: 2010-07-02T10:01:49Z

[Term]
id: GO:0039016
name: cell-cell signaling involved in pronephros development
namespace: biological_process
def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10]
synonym: "cell-cell signaling involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10]
synonym: "cell-cell signalling involved in pronephros development" EXACT [GOC:mah]
is_a: GO:0060995 ! cell-cell signaling involved in kidney development
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: part_of GO:0048793 ! pronephros development
relationship: part_of GO:0048793 ! pronephros development
created_by: bf
creation_date: 2010-07-02T10:03:16Z

[Term]
id: GO:0039017
name: pattern specification involved in pronephros development
namespace: biological_process
def: "Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10]
synonym: "pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0061004 ! pattern specification involved in kidney development
intersection_of: GO:0007389 ! pattern specification process
intersection_of: part_of GO:0048793 ! pronephros development
relationship: part_of GO:0048793 ! pronephros development
created_by: bf
creation_date: 2010-07-02T10:04:39Z

[Term]
id: GO:0039019
name: pronephric nephron development
namespace: biological_process
def: "The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10, XAO:00002785]
is_a: GO:0072006 ! nephron development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005309 ! pronephric nephron
relationship: part_of GO:0048793 ! pronephros development
relationship: results_in_development_of UBERON:0005309 ! pronephric nephron
created_by: bf
creation_date: 2010-07-02T10:10:20Z

[Term]
id: GO:0039020
name: pronephric nephron tubule development
namespace: biological_process
def: "The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct." [GOC:mtg_kidney_jan10, PMID:19909807, PMID:9268568]
is_a: GO:0072080 ! nephron tubule development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005310 ! pronephric nephron tubule
relationship: part_of GO:0039019 ! pronephric nephron development
relationship: results_in_development_of UBERON:0005310 ! pronephric nephron tubule
created_by: bf
creation_date: 2010-07-02T10:11:36Z

[Term]
id: GO:0039022
name: pronephric duct development
namespace: biological_process
def: "The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney." [GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150]
is_a: GO:0072176 ! nephric duct development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003060 ! pronephric duct
relationship: part_of GO:0048793 ! pronephros development
relationship: results_in_development_of UBERON:0003060 ! pronephric duct
created_by: bf
creation_date: 2010-07-02T10:15:03Z

[Term]
id: GO:0039023
name: pronephric duct morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney." [GOC:mtg_kidney_jan10, XAO:0000063, ZFA:0000150]
is_a: GO:0072178 ! nephric duct morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003060 ! pronephric duct
relationship: part_of GO:0039022 ! pronephric duct development
relationship: part_of GO:0072114 ! pronephros morphogenesis
relationship: results_in_morphogenesis_of UBERON:0003060 ! pronephric duct
created_by: bf
creation_date: 2010-07-02T10:18:09Z

[Term]
id: GO:0040003
name: chitin-based cuticle development
namespace: biological_process
def: "Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu]
synonym: "chitin-based cuticle anabolism" EXACT []
synonym: "chitin-based cuticle biosynthetic process" EXACT []
synonym: "chitin-based cuticle formation" EXACT []
synonym: "chitin-based cuticle synthesis" EXACT []
is_a: GO:0042335 ! cuticle development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001001 ! chitin-based cuticle
relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda
relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda
relationship: results_in_development_of UBERON:0001001 ! chitin-based cuticle

[Term]
id: GO:0040007
name: growth
namespace: biological_process
alt_id: GO:0048590
def: "The increase in size or mass of an entire organism, a part of an organism or a cell." [GOC:bf, GOC:ma]
comment: See also the biological process term 'cell growth ; GO:0016049'.
subset: gocheck_do_not_annotate
subset: goslim_chembl
subset: goslim_pir
subset: goslim_plant
synonym: "growth pattern" RELATED []
synonym: "non-developmental growth" RELATED [GOC:mah]
is_a: GO:0008150 ! biological process
relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms
relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms

[Term]
id: GO:0040008
name: regulation of growth
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." [GOC:ems, GOC:mah]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0040007 ! growth
relationship: regulates GO:0040007 ! growth

[Term]
id: GO:0040011
name: locomotion
namespace: biological_process
def: "Self-propelled movement of a cell or organism from one location to another." [GOC:dgh]
subset: goslim_chembl
subset: goslim_pir
is_a: GO:0008150 ! biological process
property_value: RO:0002161 NCBITaxon:451864

[Term]
id: GO:0040012
name: regulation of locomotion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." [GOC:ems]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0040011 ! locomotion
relationship: regulates GO:0040011 ! locomotion

[Term]
id: GO:0040013
name: negative regulation of locomotion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators]
synonym: "down regulation of locomotion" EXACT []
synonym: "down-regulation of locomotion" EXACT []
synonym: "downregulation of locomotion" EXACT []
synonym: "inhibition of locomotion" NARROW []
is_a: GO:0040012 ! regulation of locomotion
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0040011 ! locomotion
relationship: negatively_regulates GO:0040011 ! locomotion

[Term]
id: GO:0040014
name: regulation of multicellular organism growth
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." [GOC:dph, GOC:ems, GOC:tb]
synonym: "regulation of body growth" EXACT [GOC:dph, GOC:tb]
synonym: "regulation of body size" EXACT [GOC:dph, GOC:tb]
is_a: GO:0048638 ! regulation of developmental growth
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035264 ! multicellular organism growth
relationship: regulates GO:0035264 ! multicellular organism growth

[Term]
id: GO:0040015
name: negative regulation of multicellular organism growth
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:ems, GOC:tb]
synonym: "negative regulation of body growth" EXACT [GOC:dph, GOC:tb]
synonym: "negative regulation of body size" EXACT [GOC:dph, GOC:tb]
is_a: GO:0040014 ! regulation of multicellular organism growth
is_a: GO:0048640 ! negative regulation of developmental growth
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035264 ! multicellular organism growth
relationship: negatively_regulates GO:0035264 ! multicellular organism growth

[Term]
id: GO:0040016
name: embryonic cleavage
namespace: biological_process
def: "The first few specialized divisions of an activated animal egg." [GOC:clt, ISBN:0070524300]
is_a: GO:0051301 ! cell division
relationship: part_of GO:0009790 ! embryo development

[Term]
id: GO:0040017
name: positive regulation of locomotion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators]
synonym: "activation of locomotion" NARROW []
synonym: "stimulation of locomotion" NARROW []
synonym: "up regulation of locomotion" EXACT []
synonym: "up-regulation of locomotion" EXACT []
synonym: "upregulation of locomotion" EXACT []
is_a: GO:0040012 ! regulation of locomotion
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0040011 ! locomotion
relationship: positively_regulates GO:0040011 ! locomotion

[Term]
id: GO:0040018
name: positive regulation of multicellular organism growth
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "positive regulation of body growth" EXACT [GOC:dph, GOC:tb]
synonym: "positive regulation of body size" EXACT [GOC:dph, GOC:tb]
is_a: GO:0040014 ! regulation of multicellular organism growth
is_a: GO:0048639 ! positive regulation of developmental growth
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035264 ! multicellular organism growth
relationship: positively_regulates GO:0035264 ! multicellular organism growth

[Term]
id: GO:0040019
name: positive regulation of embryonic development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of embryonic development." [GOC:go_curators]
synonym: "activation of embryonic development" NARROW []
synonym: "stimulation of embryonic development" NARROW []
synonym: "up regulation of embryonic development" EXACT []
synonym: "up-regulation of embryonic development" EXACT []
synonym: "upregulation of embryonic development" EXACT []
is_a: GO:0045995 ! regulation of embryonic development
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009790 ! embryo development
relationship: positively_regulates GO:0009790 ! embryo development

[Term]
id: GO:0040020
name: regulation of meiotic nuclear division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." [GOC:ems, GOC:ma]
synonym: "regulation of meiosis" BROAD [GOC:vw]
is_a: GO:0010564 ! regulation of cell cycle process
is_a: GO:0051445 ! regulation of meiotic cell cycle
is_a: GO:0051783 ! regulation of nuclear division
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0140013 ! meiotic nuclear division
relationship: regulates GO:0140013 ! meiotic nuclear division

[Term]
id: GO:0040034
name: regulation of development, heterochronic
namespace: biological_process
def: "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." [PMID:9442909]
synonym: "developmental timing" RELATED []
synonym: "heterochronic regulation of development" EXACT []
synonym: "temporal regulation of development" EXACT []
is_a: GO:0050793 ! regulation of developmental process

[Term]
id: GO:0042063
name: gliogenesis
namespace: biological_process
def: "The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia." [GOC:dgh, GOC:jid]
synonym: "glial cell generation" EXACT systematic_synonym []
is_a: GO:0022008 ! neurogenesis
intersection_of: GO:0008150 ! biological process
intersection_of: results_in_formation_of_anatomical_entity CL:0000125 ! glial cell
relationship: results_in_formation_of_anatomical_entity CL:0000125 ! glial cell

[Term]
id: GO:0042065
name: glial cell growth
namespace: biological_process
def: "Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:dph, GOC:isa_complete, GOC:jid]
is_a: GO:0048588 ! developmental cell growth
intersection_of: GO:0040007 ! growth
intersection_of: results_in_growth_of CL:0000125 ! glial cell
relationship: part_of GO:0042063 ! gliogenesis
relationship: results_in_growth_of CL:0000125 ! glial cell

[Term]
id: GO:0042069
name: regulation of catecholamine metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." [GOC:go_curators]
synonym: "regulation of catecholamine metabolism" EXACT []
is_a: GO:0031323 ! regulation of cellular metabolic process
is_a: GO:0033238 ! regulation of amine metabolic process
is_a: GO:0080090 ! regulation of primary metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006584 ! catecholamine metabolic process
relationship: regulates GO:0006584 ! catecholamine metabolic process

[Term]
id: GO:0042073
name: intraciliary transport
namespace: biological_process
alt_id: GO:0035734
def: "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins." [GOC:cilia, GOC:kmv, PMID:17981739, PMID:18180368, PMID:22869374, Reactome:R-HSA-5620924.2]
comment: Note that we deem cilium and microtubule-based flagellum to be equivalent.
synonym: "IFT" RELATED []
synonym: "intraflagellar transport" EXACT []
synonym: "intraflagellar transport involved in cilium organization" EXACT []
synonym: "intraflagellar transport involved in microtubule-based flagellum organisation" EXACT []
xref: Wikipedia:Intraflagellar_transport
is_a: GO:0010970 ! transport along microtubule
is_a: GO:0031503 ! protein-containing complex localization
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input GO:0032991 ! protein-containing complex
intersection_of: occurs_in GO:0005929 ! cilium
intersection_of: results_in_transport_along GO:0005874 ! microtubule
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: occurs_in GO:0005929 ! cilium
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
relationship: part_of GO:0044782 ! cilium organization
property_value: RO:0002161 NCBITaxon:3176
property_value: RO:0002161 NCBITaxon:3312
property_value: RO:0002161 NCBITaxon:3378
property_value: RO:0002161 NCBITaxon:3398
property_value: RO:0002161 NCBITaxon:4890
property_value: RO:0002161 NCBITaxon:5782

[Term]
id: GO:0042074
name: cell migration involved in gastrulation
namespace: biological_process
def: "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." [GOC:jl, http://www.cellmigration.org/, ISBN:0878932437]
is_a: GO:0001667 ! ameboidal-type cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: part_of GO:0007369 ! gastrulation
relationship: part_of GO:0007369 ! gastrulation

[Term]
id: GO:0042078
name: germ-line stem cell division
namespace: biological_process
alt_id: GO:0048131
def: "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes." [GOC:jid, PMID:2279698]
synonym: "germ-line stem cell renewal" EXACT []
is_a: GO:0017145 ! stem cell division
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
intersection_of: GO:0051301 ! cell division
intersection_of: has_primary_input CL:0000014 ! germ line stem cell
relationship: has_primary_input CL:0000014 ! germ line stem cell
relationship: part_of GO:0007281 ! germ cell development

[Term]
id: GO:0042098
name: T cell proliferation
namespace: biological_process
alt_id: GO:0042111
def: "The expansion of a T cell population by cell division. Follows T cell activation." [GOC:jl]
synonym: "T lymphocyte proliferation" EXACT []
synonym: "T-cell proliferation" EXACT []
synonym: "T-lymphocyte proliferation" EXACT []
is_a: GO:0042110 ! T cell activation
is_a: GO:0046651 ! lymphocyte proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000084 ! T cell
relationship: acts_on_population_of CL:0000084 ! T cell

[Term]
id: GO:0042102
name: positive regulation of T cell proliferation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of T cell proliferation." [GOC:ai]
synonym: "activation of T cell proliferation" NARROW []
synonym: "positive regulation of T lymphocyte proliferation" EXACT []
synonym: "positive regulation of T-lymphocyte proliferation" EXACT []
synonym: "stimulation of T cell proliferation" NARROW []
synonym: "up regulation of T cell proliferation" EXACT []
synonym: "up-regulation of T cell proliferation" EXACT []
synonym: "upregulation of T cell proliferation" EXACT []
is_a: GO:0042129 ! regulation of T cell proliferation
is_a: GO:0050671 ! positive regulation of lymphocyte proliferation
is_a: GO:0050870 ! positive regulation of T cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0042098 ! T cell proliferation
relationship: positively_regulates GO:0042098 ! T cell proliferation

[Term]
id: GO:0042103
name: positive regulation of T cell homeostatic proliferation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of resting T cell proliferation." [GOC:jl]
synonym: "activation of T cell homeostatic proliferation" NARROW []
synonym: "positive regulation of resting T cell proliferation" EXACT []
synonym: "positive regulation of T lymphocyte homeostatic proliferation" EXACT []
synonym: "positive regulation of T-cell homeostatic proliferation" EXACT []
synonym: "positive regulation of T-lymphocyte homeostatic proliferation" EXACT []
synonym: "stimulation of T cell homeostatic proliferation" NARROW []
synonym: "up regulation of T cell homeostatic proliferation" EXACT []
synonym: "up-regulation of T cell homeostatic proliferation" EXACT []
synonym: "upregulation of T cell homeostatic proliferation" EXACT []
is_a: GO:0042102 ! positive regulation of T cell proliferation
is_a: GO:0046013 ! regulation of T cell homeostatic proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001777 ! T cell homeostatic proliferation
relationship: positively_regulates GO:0001777 ! T cell homeostatic proliferation

[Term]
id: GO:0042110
name: T cell activation
namespace: biological_process
def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:mgi_curators, ISBN:0781735149]
synonym: "T lymphocyte activation" EXACT []
synonym: "T-cell activation" EXACT []
synonym: "T-lymphocyte activation" EXACT []
is_a: GO:0046649 ! lymphocyte activation
intersection_of: GO:0001775 ! cell activation
intersection_of: has_primary_input CL:0000084 ! T cell
relationship: has_primary_input CL:0000084 ! T cell

[Term]
id: GO:0042118
name: endothelial cell activation
namespace: biological_process
def: "The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149, PMID:12851652, PMID:14581484]
is_a: GO:0001775 ! cell activation
intersection_of: GO:0001775 ! cell activation
intersection_of: has_primary_input CL:0000115 ! endothelial cell
relationship: has_primary_input CL:0000115 ! endothelial cell

[Term]
id: GO:0042127
name: regulation of cell population proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl]
synonym: "regulation of cell proliferation" RELATED []
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008283 ! cell population proliferation
relationship: regulates GO:0008283 ! cell population proliferation
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0042129
name: regulation of T cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of T cell proliferation." [GOC:jl]
synonym: "regulation of T lymphocyte proliferation" EXACT []
synonym: "regulation of T-cell proliferation" EXACT []
synonym: "regulation of T-lymphocyte proliferation" EXACT []
is_a: GO:0050670 ! regulation of lymphocyte proliferation
is_a: GO:0050863 ! regulation of T cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042098 ! T cell proliferation
relationship: regulates GO:0042098 ! T cell proliferation

[Term]
id: GO:0042130
name: negative regulation of T cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of T cell proliferation." [GOC:jl]
synonym: "down regulation of T cell proliferation" EXACT []
synonym: "down-regulation of T cell proliferation" EXACT []
synonym: "downregulation of T cell proliferation" EXACT []
synonym: "inhibition of T cell proliferation" NARROW []
synonym: "negative regulation of T lymphocyte proliferation" EXACT []
synonym: "negative regulation of T-cell proliferation" EXACT []
synonym: "negative regulation of T-lymphocyte proliferation" EXACT []
is_a: GO:0042129 ! regulation of T cell proliferation
is_a: GO:0050672 ! negative regulation of lymphocyte proliferation
is_a: GO:0050868 ! negative regulation of T cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042098 ! T cell proliferation
relationship: negatively_regulates GO:0042098 ! T cell proliferation

[Term]
id: GO:0042175
name: nuclear outer membrane-endoplasmic reticulum membrane network
namespace: cellular_component
def: "The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane." [GOC:bf, GOC:jl, GOC:mah, GOC:mcc, GOC:pr, GOC:vw]
synonym: "NE-ER continuum" RELATED []
synonym: "NE-ER network" RELATED []
synonym: "nuclear envelope-endoplasmic reticulum continuum" RELATED []
synonym: "nuclear envelope-endoplasmic reticulum network" RELATED [GOC:mah]
synonym: "nuclear envelope-ER network" RELATED []
synonym: "nuclear membrane-endoplasmic reticulum continuum" EXACT [GOC:mah]
synonym: "nuclear membrane-ER network" EXACT [GOC:mah]
is_a: GO:0016020 ! membrane
relationship: part_of GO:0012505 ! endomembrane system

[Term]
id: GO:0042176
name: regulation of protein catabolic process
namespace: biological_process
alt_id: GO:1903362
alt_id: GO:2000598
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators, GOC:jl]
synonym: "regulation of cellular protein breakdown" EXACT [GOC:TermGenie]
synonym: "regulation of cellular protein catabolic process" EXACT []
synonym: "regulation of cellular protein catabolism" EXACT [GOC:TermGenie]
synonym: "regulation of cellular protein degradation" EXACT [GOC:TermGenie]
synonym: "regulation of cyclin breakdown" NARROW [GOC:obol]
synonym: "regulation of cyclin catabolic process" NARROW []
synonym: "regulation of cyclin catabolism" NARROW [GOC:obol]
synonym: "regulation of cyclin degradation" NARROW [GOC:obol]
synonym: "regulation of degradation of cyclin" NARROW [GOC:obol]
synonym: "regulation of protein breakdown" EXACT []
synonym: "regulation of protein catabolism" EXACT []
synonym: "regulation of protein degradation" EXACT []
is_a: GO:0009894 ! regulation of catabolic process
is_a: GO:0051246 ! regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030163 ! protein catabolic process
relationship: regulates GO:0030163 ! protein catabolic process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI
created_by: kmv
creation_date: 2014-08-21T15:05:45Z

[Term]
id: GO:0042177
name: negative regulation of protein catabolic process
namespace: biological_process
alt_id: GO:1903363
alt_id: GO:2000599
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process." [GO_REF:0000058, GOC:kmv, GOC:obol, GOC:TermGenie, PMID:24785082]
synonym: "down regulation of cellular protein breakdown" EXACT [GOC:TermGenie]
synonym: "down regulation of cellular protein catabolic process" EXACT [GOC:TermGenie]
synonym: "down regulation of cellular protein catabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of cellular protein degradation" EXACT [GOC:TermGenie]
synonym: "down regulation of protein catabolic process" EXACT []
synonym: "down-regulation of cellular protein breakdown" EXACT [GOC:TermGenie]
synonym: "down-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of cellular protein catabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of cellular protein degradation" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein catabolic process" EXACT []
synonym: "downregulation of cellular protein breakdown" EXACT [GOC:TermGenie]
synonym: "downregulation of cellular protein catabolic process" EXACT [GOC:TermGenie]
synonym: "downregulation of cellular protein catabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of cellular protein degradation" EXACT [GOC:TermGenie]
synonym: "downregulation of protein catabolic process" EXACT []
synonym: "inhibition of cellular protein breakdown" NARROW [GOC:TermGenie]
synonym: "inhibition of cellular protein catabolic process" NARROW [GOC:TermGenie]
synonym: "inhibition of cellular protein catabolism" NARROW [GOC:TermGenie]
synonym: "inhibition of cellular protein degradation" NARROW [GOC:TermGenie]
synonym: "inhibition of protein catabolic process" NARROW []
synonym: "negative regulation of cellular protein breakdown" EXACT [GOC:TermGenie]
synonym: "negative regulation of cellular protein catabolic process" EXACT []
synonym: "negative regulation of cellular protein catabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of cellular protein degradation" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein breakdown" EXACT []
synonym: "negative regulation of protein catabolism" EXACT []
synonym: "negative regulation of protein degradation" EXACT []
is_a: GO:0009895 ! negative regulation of catabolic process
is_a: GO:0042176 ! regulation of protein catabolic process
is_a: GO:0051248 ! negative regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030163 ! protein catabolic process
relationship: negatively_regulates GO:0030163 ! protein catabolic process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI

[Term]
id: GO:0042180
name: cellular ketone metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:jl, ISBN:0787650153]
subset: goslim_pir
synonym: "ketone metabolism" EXACT []
is_a: GO:0044237 ! cellular metabolic process
is_a: GO:0044281 ! small molecule metabolic process
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:17087 ! ketone
relationship: has_primary_input_or_output CHEBI:17087 ! ketone

[Term]
id: GO:0042181
name: ketone biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators]
synonym: "ketone anabolism" EXACT []
synonym: "ketone biosynthesis" EXACT []
synonym: "ketone formation" EXACT []
synonym: "ketone synthesis" EXACT []
is_a: GO:0042180 ! cellular ketone metabolic process
is_a: GO:0044249 ! cellular biosynthetic process
is_a: GO:0044283 ! small molecule biosynthetic process
is_a: GO:1901576 ! organic substance biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:17087 ! ketone
relationship: has_primary_output CHEBI:17087 ! ketone

[Term]
id: GO:0042182
name: ketone catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators]
synonym: "ketone breakdown" EXACT []
synonym: "ketone catabolism" EXACT []
synonym: "ketone degradation" EXACT []
is_a: GO:0042180 ! cellular ketone metabolic process
is_a: GO:0044248 ! cellular catabolic process
is_a: GO:0044282 ! small molecule catabolic process
is_a: GO:1901575 ! organic substance catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:17087 ! ketone
relationship: has_primary_input CHEBI:17087 ! ketone

[Term]
id: GO:0042221
name: response to chemical
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." [GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
subset: goslim_candida
subset: goslim_drosophila
subset: goslim_metagenomics
subset: goslim_plant
subset: goslim_yeast
synonym: "response to chemical stimulus" EXACT [GOC:dos]
synonym: "response to chemical substance" EXACT []
is_a: GO:0050896 ! response to stimulus
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:24431 ! chemical entity
relationship: has_primary_input CHEBI:24431 ! chemical entity

[Term]
id: GO:0042254
name: ribosome biogenesis
namespace: biological_process
alt_id: GO:0007046
def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis." [GOC:ma, PMID:26404467, Wikipedia:Ribosome_biogenesis]
subset: goslim_candida
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pir
subset: goslim_pombe
subset: goslim_prokaryote
synonym: "ribosome biogenesis and assembly" EXACT []
is_a: GO:0022613 ! ribonucleoprotein complex biogenesis

[Term]
id: GO:0042255
name: ribosome assembly
namespace: biological_process
alt_id: GO:0042257
def: "The aggregation, arrangement and bonding together of the mature ribosome and of its subunits." [GOC:ma, PMID:30467428]
subset: goslim_yeast
synonym: "ribosomal subunit assembly" NARROW [GOC:mah, GOC:vw]
is_a: GO:0140694 ! non-membrane-bounded organelle assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0005840 ! ribosome
relationship: part_of GO:0042254 ! ribosome biogenesis
relationship: results_in_assembly_of GO:0005840 ! ribosome

[Term]
id: GO:0042325
name: regulation of phosphorylation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." [GOC:jl]
is_a: GO:0019220 ! regulation of phosphate metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016310 ! phosphorylation
relationship: regulates GO:0016310 ! phosphorylation

[Term]
id: GO:0042326
name: negative regulation of phosphorylation
namespace: biological_process
def: "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." [GOC:jl]
synonym: "down regulation of phosphorylation" EXACT []
synonym: "down-regulation of phosphorylation" EXACT []
synonym: "downregulation of phosphorylation" EXACT []
synonym: "inhibition of phosphorylation" NARROW []
is_a: GO:0042325 ! regulation of phosphorylation
is_a: GO:0045936 ! negative regulation of phosphate metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0016310 ! phosphorylation
relationship: negatively_regulates GO:0016310 ! phosphorylation

[Term]
id: GO:0042327
name: positive regulation of phosphorylation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." [GOC:jl]
synonym: "activation of phosphorylation" NARROW []
synonym: "stimulation of phosphorylation" NARROW []
synonym: "up regulation of phosphorylation" EXACT []
synonym: "up-regulation of phosphorylation" EXACT []
synonym: "upregulation of phosphorylation" EXACT []
is_a: GO:0042325 ! regulation of phosphorylation
is_a: GO:0045937 ! positive regulation of phosphate metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0016310 ! phosphorylation
relationship: positively_regulates GO:0016310 ! phosphorylation

[Term]
id: GO:0042335
name: cuticle development
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss." [ISBN:0192800825]
subset: goslim_drosophila
synonym: "cuticle anabolism" EXACT []
synonym: "cuticle biosynthesis" EXACT []
synonym: "cuticle biosynthetic process" EXACT []
synonym: "cuticle formation" EXACT []
synonym: "cuticle synthesis" EXACT []
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001002 ! cuticle
relationship: part_of GO:0007275 ! multicellular organism development
relationship: results_in_development_of UBERON:0001002 ! cuticle

[Term]
id: GO:0042391
name: regulation of membrane potential
namespace: biological_process
def: "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:jl, GOC:mtg_cardio, GOC:tb, ISBN:0198506732]
is_a: BFO:0000015 ! process
relationship: has_part GO:0034220 ! monoatomic ion transmembrane transport

[Term]
id: GO:0042401
name: biogenic amine biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172]
synonym: "biogenic amine anabolism" EXACT []
synonym: "biogenic amine biosynthesis" EXACT []
synonym: "biogenic amine formation" EXACT []
synonym: "biogenic amine synthesis" EXACT []
synonym: "cellular biogenic amine biosynthetic process" EXACT []
is_a: GO:0006576 ! biogenic amine metabolic process
is_a: GO:0009309 ! amine biosynthetic process

[Term]
id: GO:0042402
name: cellular biogenic amine catabolic process
namespace: biological_process
def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:go_curators, GOC:jl, ISBN:0198506732]
synonym: "biogenic amine breakdown" EXACT []
synonym: "biogenic amine catabolism" EXACT []
synonym: "biogenic amine degradation" EXACT []
is_a: GO:0009310 ! amine catabolic process

[Term]
id: GO:0042415
name: norepinephrine metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732]
synonym: "levarterenol metabolic process" EXACT []
synonym: "levarterenol metabolism" EXACT []
synonym: "noradrenaline metabolic process" EXACT []
synonym: "noradrenaline metabolism" EXACT []
synonym: "norepinephrine metabolism" EXACT []
is_a: GO:0006807 ! nitrogen compound metabolic process
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:72587 ! (R)-noradrenaline(1+)
relationship: has_primary_input_or_output CHEBI:72587 ! (R)-noradrenaline(1+)

[Term]
id: GO:0042421
name: norepinephrine biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732]
synonym: "levarterenol biosynthesis" EXACT []
synonym: "levarterenol biosynthetic process" EXACT []
synonym: "noradrenaline biosynthesis" EXACT []
synonym: "noradrenaline biosynthetic process" EXACT []
synonym: "norepinephrine anabolism" EXACT []
synonym: "norepinephrine biosynthesis" EXACT []
synonym: "norepinephrine formation" EXACT []
synonym: "norepinephrine synthesis" EXACT []
is_a: GO:0042415 ! norepinephrine metabolic process
is_a: GO:1901576 ! organic substance biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:72587 ! (R)-noradrenaline(1+)
relationship: has_primary_output CHEBI:72587 ! (R)-noradrenaline(1+)

[Term]
id: GO:0042422
name: norepinephrine catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732]
synonym: "levarterenol catabolic process" EXACT []
synonym: "levarterenol catabolism" EXACT []
synonym: "noradrenaline catabolic process" EXACT []
synonym: "noradrenaline catabolism" EXACT []
synonym: "norepinephrine breakdown" EXACT []
synonym: "norepinephrine catabolism" EXACT []
synonym: "norepinephrine degradation" EXACT []
xref: Wikipedia:Norepinephrine#Degradation
is_a: GO:0042415 ! norepinephrine metabolic process
is_a: GO:1901575 ! organic substance catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+)
relationship: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+)

[Term]
id: GO:0042423
name: catecholamine biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732]
synonym: "catecholamine anabolism" EXACT []
synonym: "catecholamine biosynthesis" EXACT []
synonym: "catecholamine formation" EXACT []
synonym: "catecholamine synthesis" EXACT []
xref: Wikipedia:Catecholamines
is_a: GO:0006584 ! catecholamine metabolic process
is_a: GO:0009713 ! catechol-containing compound biosynthetic process
is_a: GO:0042401 ! biogenic amine biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:33567 ! catecholamine
relationship: has_primary_output CHEBI:33567 ! catecholamine

[Term]
id: GO:0042424
name: catecholamine catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732]
synonym: "catecholamine breakdown" EXACT []
synonym: "catecholamine catabolism" EXACT []
synonym: "catecholamine degradation" EXACT []
is_a: GO:0006584 ! catecholamine metabolic process
is_a: GO:0019614 ! catechol-containing compound catabolic process
is_a: GO:0042402 ! cellular biogenic amine catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:33567 ! catecholamine
relationship: has_primary_input CHEBI:33567 ! catecholamine

[Term]
id: GO:0042427
name: serotonin biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732]
synonym: "serotonin anabolism" EXACT []
synonym: "serotonin biosynthesis" EXACT []
synonym: "serotonin formation" EXACT []
synonym: "serotonin synthesis" EXACT []
xref: Wikipedia:Serotonin
is_a: GO:0009058 ! biosynthetic process
is_a: GO:0042428 ! serotonin metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:350546 ! serotonin(1+)
relationship: has_primary_output CHEBI:350546 ! serotonin(1+)

[Term]
id: GO:0042428
name: serotonin metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732]
synonym: "serotonin metabolism" EXACT []
is_a: GO:0018958 ! phenol-containing compound metabolic process
is_a: GO:0042430 ! indole-containing compound metabolic process
is_a: GO:0097164 ! ammonium ion metabolic process
is_a: GO:1901160 ! primary amino compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:350546 ! serotonin(1+)
relationship: has_primary_input_or_output CHEBI:350546 ! serotonin(1+)

[Term]
id: GO:0042429
name: serotonin catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732]
synonym: "serotonin breakdown" EXACT []
synonym: "serotonin catabolism" EXACT []
synonym: "serotonin degradation" EXACT []
is_a: GO:0009056 ! catabolic process
is_a: GO:0042428 ! serotonin metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+)
relationship: has_primary_input CHEBI:350546 ! serotonin(1+)

[Term]
id: GO:0042430
name: indole-containing compound metabolic process
namespace: biological_process
alt_id: GO:0042434
def: "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl, GOC:mah]
synonym: "indole and derivative metabolic process" EXACT []
synonym: "indole and derivative metabolism" EXACT []
synonym: "indole derivative metabolic process" NARROW []
synonym: "indole derivative metabolism" NARROW []
synonym: "indole-containing compound metabolism" EXACT []
synonym: "ketole metabolic process" EXACT []
synonym: "ketole metabolism" EXACT []
is_a: GO:0006725 ! cellular aromatic compound metabolic process
is_a: GO:0034641 ! cellular nitrogen compound metabolic process
is_a: GO:0046483 ! heterocycle metabolic process
is_a: GO:1901360 ! organic cyclic compound metabolic process
is_a: GO:1901564 ! organonitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:24828 ! indoles
relationship: has_primary_input_or_output CHEBI:24828 ! indoles

[Term]
id: GO:0042435
name: indole-containing compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl]
synonym: "indole derivative biosynthesis" EXACT []
synonym: "indole derivative biosynthetic process" EXACT []
synonym: "indole-containing compound anabolism" EXACT []
synonym: "indole-containing compound biosynthesis" EXACT []
synonym: "indole-containing compound formation" EXACT []
synonym: "indole-containing compound synthesis" EXACT []
is_a: GO:0018130 ! heterocycle biosynthetic process
is_a: GO:0019438 ! aromatic compound biosynthetic process
is_a: GO:0042430 ! indole-containing compound metabolic process
is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process
is_a: GO:1901362 ! organic cyclic compound biosynthetic process
is_a: GO:1901566 ! organonitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:24828 ! indoles
relationship: has_primary_output CHEBI:24828 ! indoles

[Term]
id: GO:0042436
name: indole-containing compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl]
synonym: "indole derivative catabolic process" EXACT []
synonym: "indole derivative catabolism" EXACT []
synonym: "indole-containing compound breakdown" EXACT []
synonym: "indole-containing compound catabolism" EXACT []
synonym: "indole-containing compound degradation" EXACT []
is_a: GO:0019439 ! aromatic compound catabolic process
is_a: GO:0042430 ! indole-containing compound metabolic process
is_a: GO:0044270 ! cellular nitrogen compound catabolic process
is_a: GO:0046700 ! heterocycle catabolic process
is_a: GO:1901361 ! organic cyclic compound catabolic process
is_a: GO:1901565 ! organonitrogen compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:24828 ! indoles
relationship: has_primary_input CHEBI:24828 ! indoles

[Term]
id: GO:0042461
name: photoreceptor cell development
namespace: biological_process
alt_id: GO:0046531
def: "Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light." [GOC:go_curators]
synonym: "photoreceptor morphogenesis" EXACT []
is_a: GO:0048666 ! neuron development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000210 ! photoreceptor cell
relationship: part_of GO:0046530 ! photoreceptor cell differentiation
relationship: results_in_development_of CL:0000210 ! photoreceptor cell

[Term]
id: GO:0042462
name: eye photoreceptor cell development
namespace: biological_process
def: "Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve." [GOC:jl, ISBN:0192800981]
is_a: GO:0042461 ! photoreceptor cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000287 ! eye photoreceptor cell
relationship: part_of GO:0001754 ! eye photoreceptor cell differentiation
relationship: results_in_development_of CL:0000287 ! eye photoreceptor cell

[Term]
id: GO:0042478
name: regulation of eye photoreceptor cell development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of eye photoreceptor development." [GOC:jl]
synonym: "regulation of eye photoreceptor development" EXACT []
is_a: GO:0046532 ! regulation of photoreceptor cell differentiation
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042462 ! eye photoreceptor cell development
relationship: regulates GO:0042462 ! eye photoreceptor cell development

[Term]
id: GO:0042479
name: positive regulation of eye photoreceptor cell development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development." [GOC:jl]
synonym: "activation of eye photoreceptor cell development" NARROW []
synonym: "positive regulation of eye photoreceptor development" EXACT []
synonym: "stimulation of eye photoreceptor cell development" NARROW []
synonym: "up regulation of eye photoreceptor cell development" EXACT []
synonym: "up-regulation of eye photoreceptor cell development" EXACT []
synonym: "upregulation of eye photoreceptor cell development" EXACT []
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0042478 ! regulation of eye photoreceptor cell development
is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0042462 ! eye photoreceptor cell development
relationship: positively_regulates GO:0042462 ! eye photoreceptor cell development

[Term]
id: GO:0042480
name: negative regulation of eye photoreceptor cell development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development." [GOC:jl]
synonym: "down regulation of eye photoreceptor cell development" EXACT []
synonym: "down-regulation of eye photoreceptor cell development" EXACT []
synonym: "downregulation of eye photoreceptor cell development" EXACT []
synonym: "inhibition of eye photoreceptor cell development" NARROW []
synonym: "negative regulation of eye photoreceptor development" EXACT []
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0042478 ! regulation of eye photoreceptor cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042462 ! eye photoreceptor cell development
relationship: negatively_regulates GO:0042462 ! eye photoreceptor cell development

[Term]
id: GO:0042551
name: neuron maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state." [GOC:dph, GOC:jl]
is_a: GO:0048469 ! cell maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000540 ! neuron
relationship: part_of GO:0048666 ! neuron development
relationship: results_in_maturation_of CL:0000540 ! neuron

[Term]
id: GO:0042588
name: zymogen granule
namespace: cellular_component
def: "A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme." [GOC:jl, ISBN:0198506732]
is_a: GO:0030141 ! secretory granule

[Term]
id: GO:0042589
name: zymogen granule membrane
namespace: cellular_component
def: "The lipid bilayer surrounding a zymogen granule." [GOC:jl]
is_a: GO:0030667 ! secretory granule membrane
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0042588 ! zymogen granule
relationship: bounding_layer_of GO:0042588 ! zymogen granule
relationship: part_of GO:0042588 ! zymogen granule

[Term]
id: GO:0042592
name: homeostatic process
namespace: biological_process
alt_id: GO:0032844
alt_id: GO:0032845
alt_id: GO:0032846
def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172]
subset: goslim_agr
subset: goslim_chembl
subset: goslim_mouse
synonym: "activation of homeostatic process" NARROW []
synonym: "homeostasis" EXACT []
synonym: "inhibition of homeostatic process" NARROW []
synonym: "negative regulation of homeostatic process" RELATED []
synonym: "positive regulation of homeostatic process" RELATED []
synonym: "regulation of homeostatic process" RELATED []
is_a: GO:0008150 ! biological process

[Term]
id: GO:0042611
name: MHC protein complex
namespace: cellular_component
def: "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0781735149, PMID:15928678, PMID:16153240]
subset: goslim_pir
is_a: GO:0098797 ! plasma membrane protein complex

[Term]
id: GO:0042613
name: MHC class II protein complex
namespace: cellular_component
def: "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0120781859, PMID:15928678]
is_a: GO:0042611 ! MHC protein complex

[Term]
id: GO:0042641
name: actomyosin
namespace: cellular_component
def: "Any complex of actin, myosin, and accessory proteins." [GOC:go_curators]
synonym: "actomyosin complex" EXACT []
synonym: "actomyosin structure" EXACT []
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of GO:0015629 ! actin cytoskeleton

[Term]
id: GO:0042670
name: retinal cone cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell." [GOC:go_curators]
is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000573 ! retinal cone cell
relationship: results_in_acquisition_of_features_of CL:0000573 ! retinal cone cell

[Term]
id: GO:0042692
name: muscle cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." [CL:0000187, GOC:go_curators]
synonym: "myogenesis" RELATED []
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000187 ! muscle cell
relationship: part_of GO:0061061 ! muscle structure development
relationship: results_in_acquisition_of_features_of CL:0000187 ! muscle cell

[Term]
id: GO:0042698
name: ovulation cycle
namespace: biological_process
def: "The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [ISBN:0721662544]
is_a: GO:0048511 ! rhythmic process
is_a: GO:0048609 ! multicellular organismal reproductive process
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota

[Term]
id: GO:0042702
name: uterine wall growth
namespace: biological_process
def: "The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels." [GOC:jl]
is_a: GO:0022602 ! ovulation cycle process
is_a: GO:0048589 ! developmental growth
intersection_of: GO:0040007 ! growth
intersection_of: results_in_growth_of UBERON:0000459 ! uterine wall
relationship: part_of GO:0001553 ! luteinization
relationship: results_in_growth_of UBERON:0000459 ! uterine wall

[Term]
id: GO:0042713
name: sperm ejaculation
namespace: biological_process
def: "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract." [GOC:jl, http://www.cogsci.princeton.edu/~wn/]
is_a: GO:0048609 ! multicellular organismal reproductive process
relationship: part_of GO:0007320 ! insemination

[Term]
id: GO:0042742
name: defense response to bacterium
namespace: biological_process
alt_id: GO:0009816
alt_id: GO:0042830
def: "Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism." [GOC:jl]
synonym: "antibacterial peptide activity" RELATED []
synonym: "defence response to bacteria" EXACT []
synonym: "defence response to bacterium" EXACT []
synonym: "defense response to bacteria" EXACT []
synonym: "defense response to bacterium, incompatible interaction" NARROW []
synonym: "resistance response to pathogenic bacteria" NARROW []
synonym: "resistance response to pathogenic bacterium" NARROW []
is_a: GO:0009617 ! response to bacterium
is_a: GO:0098542 ! defense response to other organism
intersection_of: GO:0006952 ! defense response
intersection_of: has_primary_input NCBITaxon:2 ! Bacteria

[Term]
id: GO:0042762
name: regulation of sulfur metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur." [GOC:go_curators]
synonym: "regulation of sulfur metabolism" EXACT []
synonym: "regulation of sulphur metabolic process" EXACT []
synonym: "regulation of sulphur metabolism" EXACT []
is_a: GO:0031323 ! regulation of cellular metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006790 ! sulfur compound metabolic process
relationship: regulates GO:0006790 ! sulfur compound metabolic process

[Term]
id: GO:0042886
name: amide transport
namespace: biological_process
def: "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732]
subset: goslim_pir
is_a: GO:0071705 ! nitrogen compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:32988 ! amide
relationship: has_primary_input CHEBI:32988 ! amide

[Term]
id: GO:0042887
name: amide transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other." [GOC:jl, ISBN:0198506732]
synonym: "amine/amide/polyamine channel activity" NARROW []
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:32988 ! amide
relationship: has_primary_input CHEBI:32988 ! amide
relationship: part_of GO:0042886 ! amide transport

[Term]
id: GO:0042981
name: regulation of apoptotic process
namespace: biological_process
def: "Any process that modulates the occurrence or rate of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis]
comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.
synonym: "apoptosis regulator activity" RELATED []
synonym: "regulation of apoptosis" NARROW []
is_a: GO:0043067 ! regulation of programmed cell death
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006915 ! apoptotic process
relationship: regulates GO:0006915 ! apoptotic process

[Term]
id: GO:0042995
name: cell projection
namespace: cellular_component
def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, http://www.cogsci.princeton.edu/~wn/]
subset: goslim_agr
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_pir
subset: goslim_prokaryote
synonym: "cell process" BROAD []
synonym: "cellular process" BROAD []
synonym: "cellular projection" EXACT []
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of CL:0000000 ! cell

[Term]
id: GO:0042996
name: regulation of Golgi to plasma membrane protein transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl]
is_a: GO:0051223 ! regulation of protein transport
is_a: GO:0060627 ! regulation of vesicle-mediated transport
is_a: GO:1903076 ! regulation of protein localization to plasma membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0043001 ! Golgi to plasma membrane protein transport
relationship: regulates GO:0043001 ! Golgi to plasma membrane protein transport

[Term]
id: GO:0042997
name: negative regulation of Golgi to plasma membrane protein transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl]
synonym: "down regulation of Golgi to plasma membrane protein transport" EXACT []
synonym: "down-regulation of Golgi to plasma membrane protein transport" EXACT []
synonym: "downregulation of Golgi to plasma membrane protein transport" EXACT []
synonym: "inhibition of Golgi to plasma membrane protein transport" NARROW []
is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport
is_a: GO:0051224 ! negative regulation of protein transport
is_a: GO:1903077 ! negative regulation of protein localization to plasma membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0043001 ! Golgi to plasma membrane protein transport
relationship: negatively_regulates GO:0043001 ! Golgi to plasma membrane protein transport

[Term]
id: GO:0042998
name: positive regulation of Golgi to plasma membrane protein transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl]
synonym: "activation of Golgi to plasma membrane protein transport" NARROW []
synonym: "stimulation of Golgi to plasma membrane protein transport" NARROW []
synonym: "up regulation of Golgi to plasma membrane protein transport" EXACT []
synonym: "up-regulation of Golgi to plasma membrane protein transport" EXACT []
synonym: "upregulation of Golgi to plasma membrane protein transport" EXACT []
is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport
is_a: GO:0051222 ! positive regulation of protein transport
is_a: GO:1903078 ! positive regulation of protein localization to plasma membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0043001 ! Golgi to plasma membrane protein transport
relationship: positively_regulates GO:0043001 ! Golgi to plasma membrane protein transport

[Term]
id: GO:0043001
name: Golgi to plasma membrane protein transport
namespace: biological_process
def: "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane." [ISBN:0716731363]
is_a: GO:0006893 ! Golgi to plasma membrane transport
is_a: GO:0015031 ! protein transport
is_a: GO:0061951 ! establishment of protein localization to plasma membrane
is_a: GO:0072659 ! protein localization to plasma membrane
intersection_of: GO:0015031 ! protein transport
intersection_of: has_target_end_location GO:0005886 ! plasma membrane
intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus
intersection_of: process_has_causal_agent GO:0031982 ! vesicle

[Term]
id: GO:0043005
name: neuron projection
namespace: cellular_component
def: "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:jl, http://www.cogsci.princeton.edu/~wn/]
subset: goslim_pir
synonym: "nerve fiber" RELATED [GOC:dph]
synonym: "neurite" NARROW []
synonym: "neuron process" EXACT []
synonym: "neuron protrusion" EXACT [NIF_Subcellular:sao250931889]
synonym: "neuronal cell projection" EXACT []
xref: NIF_Subcellular:sao867568886
is_a: GO:0120025 ! plasma membrane bounded cell projection
intersection_of: GO:0120025 ! plasma membrane bounded cell projection
intersection_of: part_of CL:0000540 ! neuron
relationship: part_of CL:0000540 ! neuron
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0043009
name: chordate embryonic development
namespace: biological_process
def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching." [GOC:mtg_sensu]
is_a: GO:0009792 ! embryo development ending in birth or egg hatching
relationship: in_taxon NCBITaxon:7711 {all_only="true"} ! Chordata
relationship: only_in_taxon NCBITaxon:7711 ! Chordata

[Term]
id: GO:0043010
name: camera-type eye development
namespace: biological_process
alt_id: GO:0001747
alt_id: GO:0031075
def: "The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:go_curators, GOC:mtg_sensu]
is_a: GO:0001654 ! eye development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000019 ! camera-type eye
relationship: results_in_development_of UBERON:0000019 ! camera-type eye
property_value: RO:0002161 NCBITaxon:6656

[Term]
id: GO:0043025
name: neuronal cell body
namespace: cellular_component
def: "The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites." [GOC:go_curators]
comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections.
subset: goslim_pir
synonym: "neuron cell body" EXACT []
synonym: "neuronal cell soma" EXACT []
xref: NIF_Subcellular:sao1044911821
xref: Wikipedia:Soma_(biology)
is_a: GO:0044297 ! cell body
intersection_of: GO:0044297 ! cell body
intersection_of: part_of CL:0000540 ! neuron
relationship: part_of GO:0036477 ! somatodendritic compartment

[Term]
id: GO:0043029
name: T cell homeostasis
namespace: biological_process
def: "The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:mgi_curators, ISBN:0781735149]
comment: Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus.
synonym: "T lymphocyte homeostasis" EXACT []
synonym: "T-cell homeostasis" EXACT []
synonym: "T-lymphocyte homeostasis" EXACT []
is_a: GO:0002260 ! lymphocyte homeostasis
intersection_of: GO:0048872 ! homeostasis of number of cells
intersection_of: acts_on_population_of CL:0000084 ! T cell
relationship: acts_on_population_of CL:0000084 ! T cell

[Term]
id: GO:0043043
name: peptide biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide." [GOC:dph, GOC:jl]
synonym: "peptide anabolism" EXACT []
synonym: "peptide biosynthesis" EXACT []
synonym: "peptide formation" EXACT []
synonym: "peptide synthesis" EXACT []
is_a: GO:0006518 ! peptide metabolic process
is_a: GO:0043604 ! amide biosynthetic process
is_a: GO:1901566 ! organonitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:16670 ! peptide
relationship: has_primary_output CHEBI:16670 ! peptide

[Term]
id: GO:0043062
name: extracellular structure organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite." [GOC:ai, GOC:dph, GOC:jl, GOC:mah]
subset: goslim_pir
subset: goslim_prokaryote
synonym: "extracellular structure organisation" EXACT []
synonym: "extracellular structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah]
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005576 ! extracellular region
relationship: results_in_organization_of GO:0005576 ! extracellular region

[Term]
id: GO:0043065
name: positive regulation of apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis]
comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.
subset: goslim_chembl
synonym: "activation of apoptosis" NARROW []
synonym: "positive regulation of apoptosis" NARROW []
synonym: "pro-apoptosis" RELATED []
synonym: "stimulation of apoptosis" NARROW []
synonym: "up regulation of apoptosis" EXACT []
synonym: "up-regulation of apoptosis" EXACT []
synonym: "upregulation of apoptosis" EXACT []
is_a: GO:0042981 ! regulation of apoptotic process
is_a: GO:0043068 ! positive regulation of programmed cell death
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006915 ! apoptotic process
relationship: positively_regulates GO:0006915 ! apoptotic process

[Term]
id: GO:0043066
name: negative regulation of apoptotic process
namespace: biological_process
alt_id: GO:0006916
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis]
comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.
synonym: "anti-apoptosis" EXACT []
synonym: "apoptosis inhibitor activity" RELATED []
synonym: "down regulation of apoptosis" EXACT []
synonym: "down-regulation of apoptosis" EXACT []
synonym: "downregulation of apoptosis" EXACT []
synonym: "inhibition of apoptosis" NARROW []
synonym: "negative regulation of apoptosis" NARROW []
synonym: "pro-survival" RELATED []
is_a: GO:0042981 ! regulation of apoptotic process
is_a: GO:0043069 ! negative regulation of programmed cell death
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006915 ! apoptotic process
relationship: negatively_regulates GO:0006915 ! apoptotic process

[Term]
id: GO:0043067
name: regulation of programmed cell death
namespace: biological_process
alt_id: GO:0043070
def: "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl]
synonym: "regulation of non-apoptotic programmed cell death" NARROW []
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0012501 ! programmed cell death
relationship: regulates GO:0012501 ! programmed cell death

[Term]
id: GO:0043068
name: positive regulation of programmed cell death
namespace: biological_process
alt_id: GO:0043071
def: "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl]
synonym: "activation of programmed cell death" NARROW []
synonym: "positive regulation of non-apoptotic programmed cell death" NARROW []
synonym: "stimulation of programmed cell death" NARROW []
synonym: "up regulation of programmed cell death" EXACT []
synonym: "up-regulation of programmed cell death" EXACT []
synonym: "upregulation of programmed cell death" EXACT []
is_a: GO:0043067 ! regulation of programmed cell death
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0012501 ! programmed cell death
relationship: positively_regulates GO:0012501 ! programmed cell death

[Term]
id: GO:0043069
name: negative regulation of programmed cell death
namespace: biological_process
alt_id: GO:0043072
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl]
synonym: "down regulation of programmed cell death" EXACT []
synonym: "down-regulation of programmed cell death" EXACT []
synonym: "downregulation of programmed cell death" EXACT []
synonym: "inhibition of programmed cell death" NARROW []
synonym: "negative regulation of non-apoptotic programmed cell death" NARROW []
is_a: GO:0043067 ! regulation of programmed cell death
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0012501 ! programmed cell death
relationship: negatively_regulates GO:0012501 ! programmed cell death

[Term]
id: GO:0043073
name: germ cell nucleus
namespace: cellular_component
def: "The nucleus of a germ cell, a reproductive cell in multicellular organisms." [CL:0000586, GOC:go_curators]
synonym: "germ-cell nucleus" EXACT []
is_a: GO:0005634 ! nucleus
intersection_of: GO:0005634 ! nucleus
intersection_of: part_of CL:0000586 ! germ cell
relationship: part_of CL:0000586 ! germ cell

[Term]
id: GO:0043085
name: positive regulation of catalytic activity
namespace: biological_process
alt_id: GO:0048554
def: "Any process that activates or increases the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw]
subset: gocheck_do_not_annotate
subset: goslim_chembl
synonym: "activation of enzyme activity" NARROW []
synonym: "activation of metalloenzyme activity" NARROW []
synonym: "positive regulation of enzyme activity" EXACT [GOC:tb]
synonym: "positive regulation of metalloenzyme activity" NARROW []
synonym: "stimulation of enzyme activity" NARROW []
synonym: "stimulation of metalloenzyme activity" NARROW []
synonym: "up regulation of enzyme activity" EXACT []
synonym: "up regulation of metalloenzyme activity" NARROW []
synonym: "up-regulation of enzyme activity" EXACT []
synonym: "up-regulation of metalloenzyme activity" NARROW []
synonym: "upregulation of enzyme activity" EXACT []
synonym: "upregulation of metalloenzyme activity" NARROW []
is_a: GO:0044093 ! positive regulation of molecular function
is_a: GO:0050790 ! regulation of catalytic activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003824 ! catalytic activity
relationship: positively_regulates GO:0003824 ! catalytic activity

[Term]
id: GO:0043086
name: negative regulation of catalytic activity
namespace: biological_process
alt_id: GO:0048553
def: "Any process that stops or reduces the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw]
subset: gocheck_do_not_annotate
synonym: "down regulation of enzyme activity" EXACT []
synonym: "down regulation of metalloenzyme activity" NARROW []
synonym: "down-regulation of enzyme activity" EXACT []
synonym: "down-regulation of metalloenzyme activity" EXACT []
synonym: "downregulation of enzyme activity" EXACT []
synonym: "downregulation of metalloenzyme activity" NARROW []
synonym: "inhibition of enzyme activity" NARROW []
synonym: "inhibition of metalloenzyme activity" NARROW []
synonym: "negative regulation of enzyme activity" EXACT [GOC:tb]
synonym: "negative regulation of metalloenzyme activity" NARROW []
is_a: GO:0044092 ! negative regulation of molecular function
is_a: GO:0050790 ! regulation of catalytic activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003824 ! catalytic activity
relationship: negatively_regulates GO:0003824 ! catalytic activity

[Term]
id: GO:0043133
name: hindgut contraction
namespace: biological_process
def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, GOC:mtg_muscle, UBERON:0001046]
is_a: GO:0006939 ! smooth muscle contraction
is_a: GO:0022600 ! digestive system process
intersection_of: GO:0006939 ! smooth muscle contraction
intersection_of: occurs_in UBERON:0001046 ! hindgut
relationship: occurs_in UBERON:0001046 ! hindgut

[Term]
id: GO:0043134
name: regulation of hindgut contraction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, UBERON:0001046]
is_a: GO:0006940 ! regulation of smooth muscle contraction
is_a: GO:0044058 ! regulation of digestive system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0043133 ! hindgut contraction
relationship: regulates GO:0043133 ! hindgut contraction

[Term]
id: GO:0043143
name: regulation of translation by machinery localization
namespace: biological_process
def: "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." [GOC:jl]
synonym: "establishment and maintenance of translational machinery localization" EXACT []
synonym: "establishment and maintenance of translational protein localization" EXACT []
synonym: "regulation of translation by machinery localisation" EXACT [GOC:mah]
synonym: "translational machinery localization" EXACT [GOC:dph, GOC:tb]
synonym: "translational protein localization" EXACT []
is_a: GO:0006417 ! regulation of translation
is_a: GO:0008104 ! protein localization
intersection_of: GO:0008104 ! protein localization
intersection_of: part_of GO:0006412 ! translation
relationship: part_of GO:0006412 ! translation

[Term]
id: GO:0043170
name: macromolecule metabolic process
namespace: biological_process
alt_id: GO:0034960
alt_id: GO:0043283
alt_id: GO:0044259
def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah]
subset: gocheck_do_not_annotate
subset: goslim_pir
synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09]
synonym: "macromolecule metabolism" EXACT []
synonym: "multicellular organismal macromolecule metabolic process" NARROW []
synonym: "organismal macromolecule metabolism" EXACT []
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:33694 ! biomacromolecule
relationship: has_primary_input_or_output CHEBI:33694 ! biomacromolecule
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI

[Term]
id: GO:0043171
name: peptide catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:jl]
synonym: "peptide breakdown" EXACT []
synonym: "peptide catabolism" EXACT []
synonym: "peptide degradation" EXACT []
is_a: GO:0006518 ! peptide metabolic process
is_a: GO:0044248 ! cellular catabolic process
is_a: GO:1901565 ! organonitrogen compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:16670 ! peptide
relationship: has_primary_input CHEBI:16670 ! peptide

[Term]
id: GO:0043200
name: response to amino acid
namespace: biological_process
alt_id: GO:0010237
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:ef, GOC:mlg]
synonym: "response to amino acid stimulus" EXACT [GOC:dos]
is_a: GO:0001101 ! response to acid chemical
is_a: GO:0010243 ! response to organonitrogen compound
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:33709 ! amino acid
relationship: has_primary_input CHEBI:33709 ! amino acid

[Term]
id: GO:0043207
name: response to external biotic stimulus
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." [GOC:go_curators]
is_a: GO:0009605 ! response to external stimulus
is_a: GO:0009607 ! response to biotic stimulus

[Term]
id: GO:0043226
name: organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators]
subset: goslim_chembl
subset: goslim_generic
subset: goslim_pir
subset: goslim_prokaryote
xref: NIF_Subcellular:sao1539965131
xref: Wikipedia:Organelle
is_a: GO:0110165 ! cellular anatomical entity

[Term]
id: GO:0043227
name: membrane-bounded organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators]
synonym: "membrane-enclosed organelle" EXACT []
xref: NIF_Subcellular:sao414196390
is_a: GO:0043226 ! organelle
intersection_of: GO:0043226 ! organelle
intersection_of: has_part GO:0016020 ! membrane
disjoint_from: GO:0043228 ! non-membrane-bounded organelle
relationship: has_part GO:0016020 ! membrane

[Term]
id: GO:0043228
name: non-membrane-bounded organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators]
subset: goslim_mouse
synonym: "biological condensate" RELATED []
synonym: "non-membrane-enclosed organelle" EXACT []
xref: NIF_Subcellular:sao1456184038
is_a: GO:0043226 ! organelle
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21881" xsd:anyURI

[Term]
id: GO:0043229
name: intracellular organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators]
subset: goslim_pir
is_a: GO:0043226 ! organelle
intersection_of: GO:0043226 ! organelle
intersection_of: part_of GO:0005622 ! intracellular anatomical structure
disjoint_from: GO:0043230 ! extracellular organelle
relationship: part_of GO:0005622 ! intracellular anatomical structure

[Term]
id: GO:0043230
name: extracellular organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi." [GOC:jl, PMID:9914479]
subset: goslim_pir
is_a: GO:0043226 ! organelle
intersection_of: GO:0043226 ! organelle
intersection_of: part_of GO:0005576 ! extracellular region
relationship: part_of GO:0005576 ! extracellular region

[Term]
id: GO:0043231
name: intracellular membrane-bounded organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators]
subset: goslim_pir
synonym: "intracellular membrane-enclosed organelle" EXACT []
is_a: GO:0043227 ! membrane-bounded organelle
is_a: GO:0043229 ! intracellular organelle
intersection_of: GO:0043227 ! membrane-bounded organelle
intersection_of: part_of GO:0005622 ! intracellular anatomical structure

[Term]
id: GO:0043232
name: intracellular non-membrane-bounded organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators]
subset: goslim_pir
synonym: "intracellular non-membrane-enclosed organelle" EXACT []
is_a: GO:0043228 ! non-membrane-bounded organelle
is_a: GO:0043229 ! intracellular organelle
intersection_of: GO:0043228 ! non-membrane-bounded organelle
intersection_of: part_of GO:0005622 ! intracellular anatomical structure

[Term]
id: GO:0043233
name: organelle lumen
namespace: cellular_component
def: "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen." [GOC:jl, GOC:mah]
subset: goslim_mouse
is_a: GO:0031974 ! membrane-enclosed lumen
intersection_of: GO:0031974 ! membrane-enclosed lumen
intersection_of: part_of GO:0043226 ! organelle
relationship: part_of GO:0043226 ! organelle

[Term]
id: GO:0043242
name: negative regulation of protein-containing complex disassembly
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl]
synonym: "down regulation of protein complex disassembly" EXACT []
synonym: "down-regulation of protein complex disassembly" EXACT []
synonym: "downregulation of protein complex disassembly" EXACT []
synonym: "inhibition of protein complex disassembly" NARROW []
synonym: "negative regulation of protein complex disassembly" RELATED []
is_a: GO:0043244 ! regulation of protein-containing complex disassembly
is_a: GO:0051129 ! negative regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032984 ! protein-containing complex disassembly
relationship: negatively_regulates GO:0032984 ! protein-containing complex disassembly

[Term]
id: GO:0043243
name: positive regulation of protein-containing complex disassembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl]
synonym: "activation of protein complex disassembly" NARROW []
synonym: "positive regulation of protein complex disassembly" RELATED []
synonym: "stimulation of protein complex disassembly" NARROW []
synonym: "up regulation of protein complex disassembly" EXACT []
synonym: "up-regulation of protein complex disassembly" EXACT []
synonym: "upregulation of protein complex disassembly" EXACT []
is_a: GO:0043244 ! regulation of protein-containing complex disassembly
is_a: GO:0051130 ! positive regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032984 ! protein-containing complex disassembly
relationship: positively_regulates GO:0032984 ! protein-containing complex disassembly

[Term]
id: GO:0043244
name: regulation of protein-containing complex disassembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl]
synonym: "regulation of protein complex disassembly" RELATED []
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032984 ! protein-containing complex disassembly
relationship: regulates GO:0032984 ! protein-containing complex disassembly

[Term]
id: GO:0043249
name: erythrocyte maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state." [GOC:devbiol, GOC:jl]
synonym: "RBC maturation" EXACT [CL:0000232]
synonym: "red blood cell maturation" EXACT [CL:0000232]
is_a: GO:0048469 ! cell maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000232 ! erythrocyte
relationship: part_of GO:0048821 ! erythrocyte development
relationship: results_in_maturation_of CL:0000232 ! erythrocyte

[Term]
id: GO:0043254
name: regulation of protein-containing complex assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein complex assembly." [GOC:jl]
synonym: "regulation of protein complex assembly" RELATED []
is_a: GO:0044087 ! regulation of cellular component biogenesis
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0065003 ! protein-containing complex assembly
relationship: regulates GO:0065003 ! protein-containing complex assembly

[Term]
id: GO:0043255
name: regulation of carbohydrate biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates." [GOC:jl]
synonym: "regulation of carbohydrate anabolism" EXACT []
synonym: "regulation of carbohydrate biosynthesis" EXACT []
synonym: "regulation of carbohydrate formation" EXACT []
synonym: "regulation of carbohydrate synthesis" EXACT []
is_a: GO:0006109 ! regulation of carbohydrate metabolic process
is_a: GO:0009889 ! regulation of biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016051 ! carbohydrate biosynthetic process
relationship: regulates GO:0016051 ! carbohydrate biosynthetic process

[Term]
id: GO:0043264
name: extracellular non-membrane-bounded organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:jl]
synonym: "extracellular non-membrane-enclosed organelle" EXACT []
is_a: GO:0043228 ! non-membrane-bounded organelle
is_a: GO:0043230 ! extracellular organelle
intersection_of: GO:0043228 ! non-membrane-bounded organelle
intersection_of: part_of GO:0005576 ! extracellular region

[Term]
id: GO:0043269
name: regulation of monoatomic ion transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl]
synonym: "regulation of ion transport" BROAD []
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006811 ! monoatomic ion transport
relationship: regulates GO:0006811 ! monoatomic ion transport

[Term]
id: GO:0043270
name: positive regulation of monoatomic ion transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl]
synonym: "activation of ion transport" NARROW []
synonym: "stimulation of ion transport" NARROW []
synonym: "up regulation of ion transport" EXACT []
synonym: "up-regulation of ion transport" EXACT []
synonym: "upregulation of ion transport" EXACT []
is_a: GO:0043269 ! regulation of monoatomic ion transport
is_a: GO:0051050 ! positive regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006811 ! monoatomic ion transport
relationship: positively_regulates GO:0006811 ! monoatomic ion transport

[Term]
id: GO:0043271
name: negative regulation of monoatomic ion transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl]
synonym: "down regulation of ion transport" EXACT []
synonym: "down-regulation of ion transport" EXACT []
synonym: "downregulation of ion transport" EXACT []
synonym: "inhibition of ion transport" NARROW []
synonym: "negative regulation of ion transport" BROAD []
is_a: GO:0043269 ! regulation of monoatomic ion transport
is_a: GO:0051051 ! negative regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006811 ! monoatomic ion transport
relationship: negatively_regulates GO:0006811 ! monoatomic ion transport

[Term]
id: GO:0043279
name: response to alkaloid
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." [GOC:jl]
is_a: GO:0010243 ! response to organonitrogen compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:22315 ! alkaloid
relationship: has_primary_input CHEBI:22315 ! alkaloid

[Term]
id: GO:0043292
name: contractile fiber
namespace: cellular_component
def: "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:go_curators, ISBN:0815316194]
synonym: "contractile fibre" EXACT []
is_a: GO:0043232 ! intracellular non-membrane-bounded organelle
is_a: GO:0099512 ! supramolecular fiber
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: part_of CL:0000187 ! muscle cell
relationship: part_of GO:0005737 ! cytoplasm

[Term]
id: GO:0043353
name: enucleate erythrocyte differentiation
namespace: biological_process
def: "The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus." [GOC:go_curators]
synonym: "enucleate RBC differentiation" EXACT [CL:0000232]
synonym: "enucleate red blood cell differentiation" EXACT [CL:0000232]
is_a: GO:0030218 ! erythrocyte differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000595 ! enucleate erythrocyte
relationship: results_in_acquisition_of_features_of CL:0000595 ! enucleate erythrocyte

[Term]
id: GO:0043354
name: enucleate erythrocyte maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus." [GOC:go_curators]
synonym: "enucleate RBC maturation" EXACT [CL:0000232]
synonym: "enucleate red blood cell maturation" EXACT [CL:0000232]
is_a: GO:0043249 ! erythrocyte maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000595 ! enucleate erythrocyte
relationship: part_of GO:0048822 ! enucleate erythrocyte development
relationship: results_in_maturation_of CL:0000595 ! enucleate erythrocyte

[Term]
id: GO:0043362
name: nucleate erythrocyte maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus." [GOC:devbiol, GOC:jl]
synonym: "nucleate RBC maturation" EXACT [CL:0000232]
synonym: "nucleate red blood cell maturation" EXACT [CL:0000232]
is_a: GO:0043249 ! erythrocyte maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000562 ! nucleate erythrocyte
relationship: part_of GO:0048823 ! nucleate erythrocyte development
relationship: results_in_maturation_of CL:0000562 ! nucleate erythrocyte

[Term]
id: GO:0043363
name: nucleate erythrocyte differentiation
namespace: biological_process
def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds." [GOC:jl]
synonym: "nucleate RBC differentiation" EXACT [CL:0000232]
synonym: "nucleate red blood cell differentiation" EXACT [CL:0000232]
is_a: GO:0030218 ! erythrocyte differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000562 ! nucleate erythrocyte
relationship: results_in_acquisition_of_features_of CL:0000562 ! nucleate erythrocyte

[Term]
id: GO:0043434
name: response to peptide hormone
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." [PMID:11027914, PMID:15134857, Wikipedia:Peptide_hormone]
synonym: "response to peptide hormone stimulus" EXACT [GOC:dos]
synonym: "response to polypeptide hormone stimulus" EXACT []
is_a: GO:0009725 ! response to hormone
is_a: GO:1901652 ! response to peptide
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:25905 ! peptide hormone
relationship: has_primary_input CHEBI:25905 ! peptide hormone

[Term]
id: GO:0043436
name: oxoacid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [Wikipedia:Oxyacid]
synonym: "keto acid metabolic process" EXACT []
synonym: "keto acid metabolism" EXACT []
synonym: "ketoacid metabolic process" EXACT []
synonym: "ketoacid metabolism" EXACT []
synonym: "oxo acid metabolic process" EXACT []
synonym: "oxo acid metabolism" EXACT []
synonym: "oxoacid metabolism" EXACT []
is_a: GO:0006082 ! organic acid metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:35406 ! oxoanion
relationship: has_primary_input_or_output CHEBI:35406 ! oxoanion

[Term]
id: GO:0043455
name: regulation of secondary metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl]
synonym: "regulation of secondary metabolism" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0019748 ! secondary metabolic process
relationship: regulates GO:0019748 ! secondary metabolic process

[Term]
id: GO:0043467
name: regulation of generation of precursor metabolites and energy
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances." [GOC:jl]
is_a: GO:0031323 ! regulation of cellular metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006091 ! generation of precursor metabolites and energy
relationship: regulates GO:0006091 ! generation of precursor metabolites and energy

[Term]
id: GO:0043470
name: regulation of carbohydrate catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates." [GOC:mlg]
is_a: GO:0006109 ! regulation of carbohydrate metabolic process
is_a: GO:0009894 ! regulation of catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016052 ! carbohydrate catabolic process
relationship: regulates GO:0016052 ! carbohydrate catabolic process

[Term]
id: GO:0043473
name: pigmentation
namespace: biological_process
def: "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells." [GOC:jl]
subset: goslim_chembl
subset: goslim_pir
is_a: GO:0008150 ! biological process
relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms
relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms

[Term]
id: GO:0043500
name: muscle adaptation
namespace: biological_process
def: "A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307]
subset: goslim_pir
synonym: "muscle plasticity" RELATED []
is_a: GO:0003012 ! muscle system process
is_a: GO:0050896 ! response to stimulus
relationship: occurs_in UBERON:0002385 ! muscle tissue

[Term]
id: GO:0043501
name: skeletal muscle adaptation
namespace: biological_process
def: "Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307]
synonym: "skeletal muscle plasticity" RELATED []
is_a: GO:0014888 ! striated muscle adaptation
intersection_of: GO:0043500 ! muscle adaptation
intersection_of: occurs_in UBERON:0001134 ! skeletal muscle tissue
relationship: occurs_in UBERON:0001134 ! skeletal muscle tissue

[Term]
id: GO:0043502
name: regulation of muscle adaptation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of muscle adaptation." [GOC:go_curators, GOC:mtg_muscle]
synonym: "regulation of muscle plasticity" RELATED []
is_a: GO:0048583 ! regulation of response to stimulus
is_a: GO:0090257 ! regulation of muscle system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0043500 ! muscle adaptation
relationship: regulates GO:0043500 ! muscle adaptation

[Term]
id: GO:0043523
name: regulation of neuron apoptotic process
namespace: biological_process
def: "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis]
synonym: "regulation of apoptosis of neuronal cells" EXACT []
synonym: "regulation of apoptosis of neurons" EXACT []
synonym: "regulation of neuron apoptosis" NARROW []
synonym: "regulation of neuron programmed cell death" EXACT []
synonym: "regulation of neuronal cell programmed cell death" EXACT []
synonym: "regulation of programmed cell death of neuronal cells" EXACT []
synonym: "regulation of programmed cell death, neurons" EXACT []
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051402 ! neuron apoptotic process
relationship: regulates GO:0051402 ! neuron apoptotic process

[Term]
id: GO:0043524
name: negative regulation of neuron apoptotic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis]
synonym: "down regulation of neuron apoptosis" EXACT []
synonym: "down-regulation of neuron apoptosis" EXACT []
synonym: "downregulation of neuron apoptosis" EXACT []
synonym: "inhibition of neuron apoptosis" NARROW []
synonym: "negative regulation of neuron apoptosis" NARROW []
synonym: "negative regulation of programmed cell death, neurons" EXACT []
synonym: "neuron survival" NARROW []
is_a: GO:0043066 ! negative regulation of apoptotic process
is_a: GO:0043523 ! regulation of neuron apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051402 ! neuron apoptotic process
relationship: negatively_regulates GO:0051402 ! neuron apoptotic process

[Term]
id: GO:0043525
name: positive regulation of neuron apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process." [GOC:go_curators, GOC:mtg_apoptosis]
synonym: "activation of neuron apoptosis" NARROW []
synonym: "positive regulation of neuron apoptosis" NARROW []
synonym: "positive regulation of programmed cell death, neurons" EXACT []
synonym: "stimulation of neuron apoptosis" NARROW []
synonym: "up regulation of neuron apoptosis" EXACT []
synonym: "up-regulation of neuron apoptosis" EXACT []
synonym: "upregulation of neuron apoptosis" EXACT []
is_a: GO:0043065 ! positive regulation of apoptotic process
is_a: GO:0043523 ! regulation of neuron apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051402 ! neuron apoptotic process
relationship: positively_regulates GO:0051402 ! neuron apoptotic process

[Term]
id: GO:0043534
name: blood vessel endothelial cell migration
namespace: biological_process
def: "The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis." [PMID:11166264]
is_a: GO:0043542 ! endothelial cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000071 ! blood vessel endothelial cell
relationship: results_in_movement_of CL:0000071 ! blood vessel endothelial cell

[Term]
id: GO:0043535
name: regulation of blood vessel endothelial cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators]
is_a: GO:0010594 ! regulation of endothelial cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0043534 ! blood vessel endothelial cell migration
relationship: regulates GO:0043534 ! blood vessel endothelial cell migration

[Term]
id: GO:0043536
name: positive regulation of blood vessel endothelial cell migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators]
synonym: "activation of blood vessel endothelial cell migration" NARROW []
synonym: "stimulation of blood vessel endothelial cell migration" NARROW []
synonym: "up regulation of blood vessel endothelial cell migration" EXACT []
synonym: "up-regulation of blood vessel endothelial cell migration" EXACT []
synonym: "upregulation of blood vessel endothelial cell migration" EXACT []
is_a: GO:0010595 ! positive regulation of endothelial cell migration
is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0043534 ! blood vessel endothelial cell migration
relationship: positively_regulates GO:0043534 ! blood vessel endothelial cell migration

[Term]
id: GO:0043537
name: negative regulation of blood vessel endothelial cell migration
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators]
synonym: "down regulation of blood vessel endothelial cell migration" EXACT []
synonym: "down-regulation of blood vessel endothelial cell migration" EXACT []
synonym: "downregulation of blood vessel endothelial cell migration" EXACT []
synonym: "inhibition of blood vessel endothelial cell migration" NARROW []
is_a: GO:0010596 ! negative regulation of endothelial cell migration
is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0043534 ! blood vessel endothelial cell migration
relationship: negatively_regulates GO:0043534 ! blood vessel endothelial cell migration

[Term]
id: GO:0043542
name: endothelial cell migration
namespace: biological_process
def: "The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:go_curators]
is_a: GO:0010631 ! epithelial cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000115 ! endothelial cell
relationship: results_in_movement_of CL:0000115 ! endothelial cell

[Term]
id: GO:0043549
name: regulation of kinase activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:bf]
subset: gocheck_do_not_annotate
is_a: GO:0042325 ! regulation of phosphorylation
is_a: GO:0051338 ! regulation of transferase activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016301 ! kinase activity
relationship: regulates GO:0016301 ! kinase activity

[Term]
id: GO:0043576
name: regulation of respiratory gaseous exchange
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment." [GOC:jl]
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system
relationship: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system

[Term]
id: GO:0043588
name: skin development
namespace: biological_process
def: "The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097]
synonym: "animal skin development" EXACT []
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002097 ! skin of body
relationship: results_in_development_of UBERON:0002097 ! skin of body
property_value: RO:0002161 NCBITaxon:50557
property_value: RO:0002161 NCBITaxon:6656

[Term]
id: GO:0043589
name: skin morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002097 ! skin of body
relationship: part_of GO:0043588 ! skin development
relationship: results_in_morphogenesis_of UBERON:0002097 ! skin of body

[Term]
id: GO:0043603
name: amide metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." [GOC:curators]
subset: goslim_pir
synonym: "amide metabolism" EXACT []
synonym: "cellular amide metabolic process" EXACT []
is_a: GO:0006807 ! nitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:32988 ! amide
relationship: has_primary_input_or_output CHEBI:32988 ! amide

[Term]
id: GO:0043604
name: amide biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators]
is_a: GO:0043603 ! amide metabolic process
is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:32988 ! amide
relationship: has_primary_output CHEBI:32988 ! amide

[Term]
id: GO:0043605
name: amide catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators]
synonym: "cellular amide catabolic process" EXACT []
is_a: GO:0009056 ! catabolic process
is_a: GO:0043603 ! amide metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_output CHEBI:32988 ! amide
relationship: has_primary_output CHEBI:32988 ! amide

[Term]
id: GO:0043648
name: dicarboxylic acid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732]
synonym: "dicarboxylate metabolic process" EXACT []
synonym: "dicarboxylate metabolism" EXACT []
synonym: "dicarboxylic acid metabolism" EXACT []
is_a: GO:0019752 ! carboxylic acid metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:35693 ! dicarboxylic acid anion
relationship: has_primary_input_or_output CHEBI:35693 ! dicarboxylic acid anion

[Term]
id: GO:0043649
name: dicarboxylic acid catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732]
synonym: "dicarboxylate catabolic process" EXACT []
synonym: "dicarboxylate catabolism" EXACT []
synonym: "dicarboxylic acid breakdown" EXACT []
synonym: "dicarboxylic acid catabolism" EXACT []
synonym: "dicarboxylic acid degradation" EXACT []
is_a: GO:0043648 ! dicarboxylic acid metabolic process
is_a: GO:0046395 ! carboxylic acid catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:35693 ! dicarboxylic acid anion
relationship: has_primary_input CHEBI:35693 ! dicarboxylic acid anion

[Term]
id: GO:0043650
name: dicarboxylic acid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732]
synonym: "dicarboxylate biosynthesis" EXACT []
synonym: "dicarboxylate biosynthetic process" EXACT []
synonym: "dicarboxylic acid anabolism" EXACT []
synonym: "dicarboxylic acid biosynthesis" EXACT []
synonym: "dicarboxylic acid formation" EXACT []
synonym: "dicarboxylic acid synthesis" EXACT []
is_a: GO:0043648 ! dicarboxylic acid metabolic process
is_a: GO:0046394 ! carboxylic acid biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:35693 ! dicarboxylic acid anion
relationship: has_primary_output CHEBI:35693 ! dicarboxylic acid anion

[Term]
id: GO:0043931
name: ossification involved in bone maturation
namespace: biological_process
def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state." [GOC:dph, GOC:mah, GOC:mtg_mpo]
synonym: "ossification involved in bone modeling" NARROW [GO_REF:0000034]
synonym: "ossification involved in skeletal development" EXACT [GOC:dph]
is_a: GO:0001503 ! ossification
intersection_of: GO:0001503 ! ossification
intersection_of: part_of GO:0070977 ! bone maturation
relationship: part_of GO:0070977 ! bone maturation

[Term]
id: GO:0043933
name: protein-containing complex organization
namespace: biological_process
alt_id: GO:0034600
alt_id: GO:0034621
alt_id: GO:0071822
def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." [GOC:mah]
synonym: "cellular macromolecular complex organization" RELATED []
synonym: "cellular macromolecular complex subunit organisation" RELATED []
synonym: "cellular macromolecular complex subunit organization" RELATED []
synonym: "macromolecular complex organization" RELATED []
synonym: "macromolecular complex subunit organisation" RELATED []
synonym: "macromolecular complex subunit organization" RELATED []
synonym: "protein complex subunit organisation" EXACT [GOC:mah]
synonym: "protein complex subunit organization" EXACT []
synonym: "protein-containing complex subunit organization" RELATED []
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0032991 ! protein-containing complex
relationship: results_in_organization_of GO:0032991 ! protein-containing complex
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI
created_by: mah
creation_date: 2010-09-08T10:01:42Z

[Term]
id: GO:0044042
name: glucan metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues." [GOC:jl]
synonym: "glucan metabolism" EXACT []
is_a: GO:0005976 ! polysaccharide metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:37163 ! glucan
relationship: has_primary_input_or_output CHEBI:37163 ! glucan

[Term]
id: GO:0044057
name: regulation of system process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." [GOC:jl]
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003008 ! system process
relationship: regulates GO:0003008 ! system process

[Term]
id: GO:0044058
name: regulation of digestive system process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jl]
is_a: GO:0044057 ! regulation of system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0022600 ! digestive system process
relationship: regulates GO:0022600 ! digestive system process

[Term]
id: GO:0044060
name: regulation of endocrine process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [GOC:jl]
synonym: "regulation of endocrine system process" EXACT []
is_a: GO:0044057 ! regulation of system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0050886 ! endocrine process
relationship: regulates GO:0050886 ! endocrine process

[Term]
id: GO:0044062
name: regulation of excretion
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity." [GOC:jl]
is_a: GO:0044057 ! regulation of system process
is_a: GO:0051046 ! regulation of secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007588 ! excretion
relationship: regulates GO:0007588 ! excretion

[Term]
id: GO:0044065
name: regulation of respiratory system process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system." [GOC:jl]
is_a: GO:0043576 ! regulation of respiratory gaseous exchange
is_a: GO:0044057 ! regulation of system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003016 ! respiratory system process
relationship: regulates GO:0003016 ! respiratory system process

[Term]
id: GO:0044085
name: cellular component biogenesis
namespace: biological_process
alt_id: GO:0071843
def: "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." [GOC:jl, GOC:mah]
subset: goslim_pir
synonym: "cellular component biogenesis at cellular level" EXACT []
is_a: GO:0071840 ! cellular component organization or biogenesis

[Term]
id: GO:0044087
name: regulation of cellular component biogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0044085 ! cellular component biogenesis
relationship: regulates GO:0044085 ! cellular component biogenesis

[Term]
id: GO:0044088
name: regulation of vacuole organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah]
synonym: "regulation of vacuole biogenesis" RELATED [GOC:mah]
synonym: "regulation of vacuole organisation" EXACT [GOC:mah]
is_a: GO:0033043 ! regulation of organelle organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007033 ! vacuole organization
relationship: regulates GO:0007033 ! vacuole organization

[Term]
id: GO:0044089
name: positive regulation of cellular component biogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl]
is_a: GO:0044087 ! regulation of cellular component biogenesis
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0044085 ! cellular component biogenesis
relationship: positively_regulates GO:0044085 ! cellular component biogenesis

[Term]
id: GO:0044090
name: positive regulation of vacuole organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah]
synonym: "positive regulation of vacuole biogenesis" RELATED [GOC:mah]
synonym: "positive regulation of vacuole organisation" EXACT [GOC:mah]
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:0044088 ! regulation of vacuole organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007033 ! vacuole organization
relationship: positively_regulates GO:0007033 ! vacuole organization

[Term]
id: GO:0044091
name: membrane biogenesis
namespace: biological_process
def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane." [GOC:jl]
is_a: GO:0044085 ! cellular component biogenesis
intersection_of: GO:0044085 ! cellular component biogenesis
intersection_of: has_primary_output GO:0016020 ! membrane
relationship: has_primary_output GO:0016020 ! membrane

[Term]
id: GO:0044092
name: negative regulation of molecular function
namespace: biological_process
def: "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl]
subset: gocheck_do_not_annotate
is_a: GO:0065009 ! regulation of molecular function
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003674 ! molecular_function
relationship: negatively_regulates GO:0003674 ! molecular_function
created_by: jl
creation_date: 2009-04-21T04:07:27Z

[Term]
id: GO:0044093
name: positive regulation of molecular function
namespace: biological_process
def: "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl]
subset: gocheck_do_not_annotate
is_a: GO:0065009 ! regulation of molecular function
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003674 ! molecular_function
relationship: positively_regulates GO:0003674 ! molecular_function
created_by: jl
creation_date: 2009-04-21T04:11:06Z

[Term]
id: GO:0044207
name: translation initiation ternary complex
namespace: cellular_component
def: "A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:jl]
synonym: "Met-tRNA/eIF2.GTP ternary complex" NARROW []
synonym: "translation initiation (ternary) complex" EXACT []
is_a: GO:1990904 ! ribonucleoprotein complex
relationship: part_of GO:0005737 ! cytoplasm
created_by: jl
creation_date: 2009-10-22T02:38:55Z

[Term]
id: GO:0044237
name: cellular metabolic process
namespace: biological_process
def: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators]
comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term.
subset: gocheck_do_not_annotate
synonym: "cellular metabolism" EXACT []
synonym: "intermediary metabolism" RELATED [GOC:mah]
is_a: GO:0008152 ! metabolic process
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0044238
name: primary metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org]
subset: gocheck_do_not_annotate
subset: goslim_pir
synonym: "primary metabolism" EXACT []
is_a: GO:0008152 ! metabolic process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI

[Term]
id: GO:0044248
name: cellular catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:jl]
synonym: "cellular breakdown" EXACT []
synonym: "cellular catabolism" EXACT []
synonym: "cellular degradation" EXACT []
is_a: GO:0009056 ! catabolic process
is_a: GO:0044237 ! cellular metabolic process

[Term]
id: GO:0044249
name: cellular biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:jl]
synonym: "cellular anabolism" EXACT []
synonym: "cellular biosynthesis" EXACT []
synonym: "cellular formation" EXACT []
synonym: "cellular synthesis" EXACT []
is_a: GO:0009058 ! biosynthetic process
is_a: GO:0044237 ! cellular metabolic process

[Term]
id: GO:0044258
name: intestinal lipid catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas." [GOC:jl, http://www.emc.maricopa.edu/]
synonym: "intestinal lipid breakdown" EXACT []
synonym: "intestinal lipid catabolism" EXACT []
synonym: "intestinal lipid degradation" EXACT []
is_a: GO:0016042 ! lipid catabolic process
intersection_of: GO:0016042 ! lipid catabolic process
intersection_of: occurs_in UBERON:0000160 ! intestine
relationship: occurs_in UBERON:0000160 ! intestine

[Term]
id: GO:0044270
name: cellular nitrogen compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732]
synonym: "nitrogen compound breakdown" BROAD []
synonym: "nitrogen compound catabolism" BROAD []
synonym: "nitrogen compound degradation" BROAD []
is_a: GO:0034641 ! cellular nitrogen compound metabolic process
is_a: GO:0044248 ! cellular catabolic process

[Term]
id: GO:0044271
name: cellular nitrogen compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732]
synonym: "nitrogen compound anabolism" BROAD []
synonym: "nitrogen compound biosynthesis" BROAD []
synonym: "nitrogen compound formation" BROAD []
synonym: "nitrogen compound synthesis" BROAD []
is_a: GO:0034641 ! cellular nitrogen compound metabolic process
is_a: GO:0044249 ! cellular biosynthetic process

[Term]
id: GO:0044272
name: sulfur compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl]
synonym: "sulfur biosynthesis" NARROW []
synonym: "sulfur biosynthetic process" NARROW []
synonym: "sulfur compound anabolism" EXACT []
synonym: "sulfur compound biosynthesis" EXACT []
synonym: "sulfur compound formation" EXACT []
synonym: "sulfur compound synthesis" EXACT []
is_a: GO:0006790 ! sulfur compound metabolic process
is_a: GO:0044249 ! cellular biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:26835 ! sulfur molecular entity
relationship: has_primary_output CHEBI:26835 ! sulfur molecular entity

[Term]
id: GO:0044273
name: sulfur compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl]
synonym: "sulfur catabolic process" NARROW []
synonym: "sulfur catabolism" NARROW []
synonym: "sulfur compound breakdown" EXACT []
synonym: "sulfur compound catabolism" EXACT []
synonym: "sulfur compound degradation" EXACT []
is_a: GO:0006790 ! sulfur compound metabolic process
is_a: GO:0044248 ! cellular catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity
relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity

[Term]
id: GO:0044281
name: small molecule metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw]
comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_metagenomics
synonym: "small molecule metabolism" EXACT []
is_a: GO:0008152 ! metabolic process
created_by: jl
creation_date: 2010-01-26T12:05:20Z

[Term]
id: GO:0044282
name: small molecule catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:vw]
comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
synonym: "small molecule catabolism" EXACT []
is_a: GO:0009056 ! catabolic process
is_a: GO:0044281 ! small molecule metabolic process
created_by: jl
creation_date: 2010-01-26T12:06:10Z

[Term]
id: GO:0044283
name: small molecule biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw]
comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
subset: goslim_prokaryote
synonym: "small molecule biosynthesis" EXACT []
is_a: GO:0009058 ! biosynthetic process
is_a: GO:0044281 ! small molecule metabolic process
created_by: jl
creation_date: 2010-01-26T12:06:49Z

[Term]
id: GO:0044297
name: cell body
namespace: cellular_component
def: "The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections." [GOC:go_curators]
comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections.
synonym: "cell soma" EXACT []
xref: FBbt:00005107
xref: FMA:67301
xref: Wikipedia:Cell_body
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of CL:0000000 ! cell
property_value: RO:0002161 NCBITaxon:4890
created_by: jl
creation_date: 2010-02-05T10:37:16Z

[Term]
id: GO:0044342
name: type B pancreatic cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin." [GOC:jl, GOC:yaf]
synonym: "pancreatic B cell proliferation" EXACT [GOC:mah]
synonym: "pancreatic beta cell proliferation" EXACT []
is_a: GO:0050673 ! epithelial cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000169 ! type B pancreatic cell
relationship: acts_on_population_of CL:0000169 ! type B pancreatic cell
created_by: jl
creation_date: 2010-08-25T01:44:51Z

[Term]
id: GO:0044346
name: fibroblast apoptotic process
namespace: biological_process
def: "Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [CL:0000057, GOC:jl, GOC:mtg_apoptosis, GOC:yaf]
synonym: "fibroblast apoptosis" NARROW []
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000057 ! fibroblast
relationship: occurs_in CL:0000057 ! fibroblast
created_by: jl
creation_date: 2010-09-23T11:33:38Z

[Term]
id: GO:0044380
name: protein localization to cytoskeleton
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within the cytoskeleton." [GOC:jl]
synonym: "protein localisation to cytoskeleton" EXACT [GOC:mah]
is_a: GO:0033365 ! protein localization to organelle
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005856 ! cytoskeleton
relationship: has_target_end_location GO:0005856 ! cytoskeleton
created_by: jl
creation_date: 2011-12-13T11:43:24Z

[Term]
id: GO:0044419
name: biological process involved in interspecies interaction between organisms
namespace: biological_process
def: "Any process evolved to enable an interaction with an organism of a different species." [GOC:cc]
subset: gocheck_do_not_annotate
subset: goslim_candida
subset: goslim_pir
synonym: "interaction with another species" EXACT []
synonym: "interspecies interaction" EXACT []
synonym: "interspecies interaction between organisms" EXACT []
synonym: "interspecies interaction with other organisms" EXACT []
is_a: GO:0008150 ! biological process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20191" xsd:anyURI
property_value: RO:0002161 NCBITaxon:4895

[Term]
id: GO:0044458
name: motile cilium assembly
namespace: biological_process
alt_id: GO:1903887
def: "The aggregation, arrangement and bonding together of a set of components to form a motile cilium." [GO_REF:0000079, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:19776033, PMID:21129373, ZFIN:dsf]
synonym: "motile primary cilia assembly" RELATED [GOC:TermGenie]
synonym: "motile primary cilia formation" RELATED [GOC:TermGenie]
synonym: "motile primary cilium assembly" RELATED []
synonym: "motile primary cilium formation" RELATED [GOC:TermGenie]
synonym: "nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "nodal cilium formation" RELATED [GOC:TermGenie]
is_a: GO:0060271 ! cilium assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0031514 ! motile cilium
relationship: results_in_assembly_of GO:0031514 ! motile cilium
created_by: krc
creation_date: 2015-02-06T17:23:23Z

[Term]
id: GO:0044550
name: secondary metabolite biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl]
subset: goslim_prokaryote
synonym: "secondary metabolite biosynthesis" EXACT []
is_a: GO:0009058 ! biosynthetic process
is_a: GO:0019748 ! secondary metabolic process
created_by: jl
creation_date: 2012-03-29T01:55:18Z

[Term]
id: GO:0044565
name: dendritic cell proliferation
namespace: biological_process
def: "The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, PMID:18469816]
is_a: GO:0032943 ! mononuclear cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000451 ! dendritic cell
relationship: acts_on_population_of CL:0000451 ! dendritic cell
created_by: jl
creation_date: 2012-04-05T04:31:39Z

[Term]
id: GO:0044566
name: chondrocyte activation
namespace: biological_process
def: "A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage." [CL:0000138, GOC:jl]
is_a: GO:0001775 ! cell activation
intersection_of: GO:0001775 ! cell activation
intersection_of: has_primary_input CL:0000138 ! chondrocyte
relationship: has_primary_input CL:0000138 ! chondrocyte
created_by: jl
creation_date: 2012-04-05T04:45:38Z

[Term]
id: GO:0044703
name: multi-organism reproductive process
namespace: biological_process
def: "A biological process that directly contributes to the process of producing new individuals, involving another organism." [GOC:jl]
subset: goslim_drosophila
is_a: GO:0022414 ! reproductive process
created_by: jl
creation_date: 2012-09-19T15:56:30Z

[Term]
id: GO:0044706
name: multi-multicellular organism process
namespace: biological_process
def: "A multicellular organism process which involves another multicellular organism of the same or different species." [GOC:jl]
is_a: GO:0032501 ! multicellular organismal process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21459" xsd:anyURI
created_by: jl
creation_date: 2012-09-19T16:06:16Z

[Term]
id: GO:0044782
name: cilium organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:jl]
comment: Note that we deem cilium and microtubule-based flagellum to be equivalent.
subset: goslim_drosophila
subset: goslim_generic
synonym: "microtubule-based flagellum organization" EXACT []
is_a: GO:0006996 ! organelle organization
is_a: GO:0120036 ! plasma membrane bounded cell projection organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005929 ! cilium
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
relationship: results_in_organization_of GO:0005929 ! cilium
created_by: jl
creation_date: 2013-03-27T15:09:58Z

[Term]
id: GO:0045026
name: plasma membrane fusion
namespace: biological_process
alt_id: GO:0006947
def: "The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell." [GOC:elh, GOC:mtg_muscle]
synonym: "cell fusion" BROAD []
synonym: "cell-cell fusion" BROAD []
is_a: GO:0007009 ! plasma membrane organization
is_a: GO:0061025 ! membrane fusion
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_fusion_of GO:0005886 ! plasma membrane
relationship: results_in_fusion_of GO:0005886 ! plasma membrane

[Term]
id: GO:0045120
name: pronucleus
namespace: cellular_component
def: "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents." [ISBN:0198506732]
xref: Wikipedia:Pronucleus
is_a: GO:0005634 ! nucleus
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa

[Term]
id: GO:0045132
name: meiotic chromosome segregation
namespace: biological_process
def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." [GOC:ai, GOC:mah]
is_a: GO:0098813 ! nuclear chromosome segregation
is_a: GO:1903046 ! meiotic cell cycle process
intersection_of: GO:0098813 ! nuclear chromosome segregation
intersection_of: part_of GO:0140013 ! meiotic nuclear division
relationship: part_of GO:0140013 ! meiotic nuclear division

[Term]
id: GO:0045137
name: development of primary sexual characteristics
namespace: biological_process
def: "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion." [GOC:ai]
is_a: GO:0003006 ! developmental process involved in reproduction
relationship: part_of GO:0007275 ! multicellular organism development
relationship: part_of GO:0007548 ! sex differentiation

[Term]
id: GO:0045144
name: meiotic sister chromatid segregation
namespace: biological_process
def: "The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." [GOC:ai, ISBN:0815316194]
synonym: "meiosis II, chromosome segregation" EXACT []
is_a: GO:0000819 ! sister chromatid segregation
is_a: GO:0045132 ! meiotic chromosome segregation
is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle
intersection_of: GO:0000819 ! sister chromatid segregation
intersection_of: part_of GO:0007135 ! meiosis II
relationship: part_of GO:0007135 ! meiosis II

[Term]
id: GO:0045165
name: cell fate commitment
namespace: biological_process
def: "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." [ISBN:0716731185]
comment: Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created.
is_a: GO:0048869 ! cellular developmental process
relationship: part_of GO:0030154 ! cell differentiation
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI

[Term]
id: GO:0045168
name: cell-cell signaling involved in cell fate commitment
namespace: biological_process
def: "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "cell fate commitment, cell-cell signaling" EXACT []
synonym: "cell fate commitment, cell-cell signalling" EXACT []
synonym: "cell-cell signaling during in cell fate commitment" EXACT []
synonym: "cell-cell signaling resulting in cell fate commitment" EXACT []
synonym: "cell-cell signalling during cell fate commitment" EXACT []
synonym: "cell-cell signalling involved in cell fate specification" NARROW [GOC:dph, GOC:tb]
synonym: "cell-cell signalling resulting in cell fate commitment" EXACT []
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: part_of GO:0045165 ! cell fate commitment
relationship: part_of GO:0045165 ! cell fate commitment

[Term]
id: GO:0045184
name: establishment of protein localization
namespace: biological_process
def: "The directed movement of a protein to a specific location." [GOC:bf]
synonym: "establishment of protein localisation" EXACT [GOC:mah]
synonym: "protein positioning" EXACT []
synonym: "protein recruitment" EXACT []
is_a: GO:0051234 ! establishment of localization
intersection_of: GO:0051234 ! establishment of localization
intersection_of: has_primary_input CHEBI:36080 ! protein
relationship: has_primary_input CHEBI:36080 ! protein

[Term]
id: GO:0045196
name: establishment or maintenance of neuroblast polarity
namespace: biological_process
alt_id: GO:0043339
alt_id: GO:0043342
def: "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mah, GOC:mtg_sensu, PMID:19375318, PMID:20066083]
synonym: "establishment and/or maintenance of neuroblast cell polarity" EXACT []
is_a: GO:0007163 ! establishment or maintenance of cell polarity
relationship: part_of GO:0055059 ! asymmetric neuroblast division

[Term]
id: GO:0045200
name: establishment of neuroblast polarity
namespace: biological_process
alt_id: GO:0043340
alt_id: GO:0043343
def: "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mtg_sensu]
synonym: "establishment of neuroblast cell polarity" EXACT []
is_a: GO:0030010 ! establishment of cell polarity
is_a: GO:0045196 ! establishment or maintenance of neuroblast polarity
intersection_of: GO:0030010 ! establishment of cell polarity
intersection_of: occurs_in CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: occurs_in CL:0000031 ! neuroblast (sensu Vertebrata)

[Term]
id: GO:0045202
name: synapse
namespace: cellular_component
def: "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." [GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110]
subset: goslim_agr
subset: goslim_drosophila
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_pir
subset: goslim_synapse
synonym: "electrotonic synapse" RELATED [NIF_Subcellular:sao1311109124]
synonym: "mixed synapse" NARROW [NIF_Subcellular:sao1506103497]
synonym: "synaptic junction" EXACT []
xref: NIF_Subcellular:sao914572699
xref: Wikipedia:Chemical_synapse
is_a: GO:0030054 ! cell junction
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa

[Term]
id: GO:0045214
name: sarcomere organization
namespace: biological_process
alt_id: GO:0006938
def: "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:bf]
synonym: "sarcomere alignment" EXACT []
synonym: "sarcomere organisation" EXACT []
is_a: GO:0031032 ! actomyosin structure organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0030017 ! sarcomere
relationship: part_of GO:0030239 ! myofibril assembly
relationship: results_in_organization_of GO:0030017 ! sarcomere

[Term]
id: GO:0045216
name: cell-cell junction organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells." [GOC:ai, GOC:dph, GOC:jl, GOC:mah]
synonym: "cell-cell junction assembly and maintenance" EXACT []
synonym: "cell-cell junction biogenesis" RELATED []
synonym: "cell-cell junction organisation" EXACT [GOC:mah]
synonym: "intercellular junction assembly and maintenance" EXACT []
is_a: GO:0034330 ! cell junction organization
intersection_of: GO:0034330 ! cell junction organization
intersection_of: results_in_organization_of GO:0005911 ! cell-cell junction
relationship: results_in_organization_of GO:0005911 ! cell-cell junction

[Term]
id: GO:0045222
name: CD4 biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions." [GOC:go_curators, ISBN:0198506732]
synonym: "CD4 anabolism" EXACT []
synonym: "CD4 biosynthesis" EXACT []
synonym: "CD4 formation" EXACT []
synonym: "CD4 synthesis" EXACT []
is_a: GO:0009101 ! glycoprotein biosynthetic process
is_a: GO:0019538 ! protein metabolic process
is_a: GO:1901566 ! organonitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output PR:000001004 ! CD4 molecule
relationship: has_primary_output PR:000001004 ! CD4 molecule

[Term]
id: GO:0045223
name: regulation of CD4 production
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators]
synonym: "regulation of CD4 anabolism" EXACT []
synonym: "regulation of CD4 biosynthesis" EXACT []
synonym: "regulation of CD4 biosynthetic process" EXACT []
synonym: "regulation of CD4 formation" EXACT []
synonym: "regulation of CD4 synthesis" EXACT []
is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process
is_a: GO:0051246 ! regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0045222 ! CD4 biosynthetic process
relationship: regulates GO:0045222 ! CD4 biosynthetic process

[Term]
id: GO:0045224
name: positive regulation of CD4 production
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators]
synonym: "activation of CD4 biosynthetic process" NARROW []
synonym: "positive regulation of CD4 anabolism" EXACT []
synonym: "positive regulation of CD4 biosynthesis" EXACT []
synonym: "positive regulation of CD4 biosynthetic process" EXACT []
synonym: "positive regulation of CD4 formation" EXACT []
synonym: "positive regulation of CD4 synthesis" EXACT []
synonym: "stimulation of CD4 biosynthetic process" NARROW []
synonym: "up regulation of CD4 biosynthetic process" EXACT []
synonym: "up-regulation of CD4 biosynthetic process" EXACT []
synonym: "upregulation of CD4 biosynthetic process" EXACT []
is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process
is_a: GO:0045223 ! regulation of CD4 production
is_a: GO:0051247 ! positive regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0045222 ! CD4 biosynthetic process
relationship: positively_regulates GO:0045222 ! CD4 biosynthetic process

[Term]
id: GO:0045225
name: negative regulation of CD4 production
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators]
synonym: "down regulation of CD4 biosynthetic process" EXACT []
synonym: "down-regulation of CD4 biosynthetic process" EXACT []
synonym: "downregulation of CD4 biosynthetic process" EXACT []
synonym: "inhibition of CD4 biosynthetic process" NARROW []
synonym: "negative regulation of CD4 anabolism" EXACT []
synonym: "negative regulation of CD4 biosynthesis" EXACT []
synonym: "negative regulation of CD4 biosynthetic process" EXACT []
synonym: "negative regulation of CD4 formation" EXACT []
synonym: "negative regulation of CD4 synthesis" EXACT []
is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process
is_a: GO:0045223 ! regulation of CD4 production
is_a: GO:0051248 ! negative regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045222 ! CD4 biosynthetic process
relationship: negatively_regulates GO:0045222 ! CD4 biosynthetic process

[Term]
id: GO:0045229
name: external encapsulating structure organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell." [GOC:ai, GOC:dph, GOC:jl, GOC:mah]
subset: goslim_pir
synonym: "external encapsulating structure organisation" EXACT []
synonym: "external encapsulating structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah]
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0030312 ! external encapsulating structure
relationship: results_in_organization_of GO:0030312 ! external encapsulating structure

[Term]
id: GO:0045321
name: leukocyte activation
namespace: biological_process
def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." [GOC:add]
synonym: "immune cell activation" EXACT []
synonym: "leucocyte activation" EXACT []
xref: Wikipedia:Immunologic_activation
is_a: GO:0001775 ! cell activation
is_a: GO:0002376 ! immune system process
intersection_of: GO:0001775 ! cell activation
intersection_of: has_primary_input CL:0000738 ! leukocyte
relationship: has_primary_input CL:0000738 ! leukocyte
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>

[Term]
id: GO:0045444
name: fat cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat." [CL:0000136, GOC:go_curators]
synonym: "adipocyte cell differentiation" EXACT []
synonym: "adipocyte differentiation" EXACT []
synonym: "adipogenesis" RELATED []
synonym: "adipose cell differentiation" EXACT []
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000136 ! adipocyte
relationship: results_in_acquisition_of_features_of CL:0000136 ! adipocyte

[Term]
id: GO:0045445
name: myoblast differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle]
synonym: "myoblast cell differentiation" EXACT []
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000056 ! myoblast
relationship: part_of GO:0061061 ! muscle structure development
relationship: results_in_acquisition_of_features_of CL:0000056 ! myoblast

[Term]
id: GO:0045446
name: endothelial cell differentiation
namespace: biological_process
def: "The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [CL:0000115, GOC:go_curators]
is_a: GO:0030855 ! epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000115 ! endothelial cell
relationship: part_of GO:0003158 ! endothelium development
relationship: results_in_acquisition_of_features_of CL:0000115 ! endothelial cell

[Term]
id: GO:0045580
name: regulation of T cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of T cell differentiation." [GOC:go_curators]
comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
synonym: "regulation of T cell development" RELATED [GOC:add]
synonym: "regulation of T lymphocyte differentiation" EXACT []
synonym: "regulation of T-cell differentiation" EXACT []
synonym: "regulation of T-lymphocyte differentiation" EXACT []
is_a: GO:0045619 ! regulation of lymphocyte differentiation
is_a: GO:0050863 ! regulation of T cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030217 ! T cell differentiation
relationship: regulates GO:0030217 ! T cell differentiation

[Term]
id: GO:0045581
name: negative regulation of T cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation." [GOC:go_curators]
comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
synonym: "down regulation of T cell differentiation" EXACT []
synonym: "down-regulation of T cell differentiation" EXACT []
synonym: "downregulation of T cell differentiation" EXACT []
synonym: "inhibition of T cell differentiation" NARROW []
synonym: "negative regulation of T cell development" RELATED [GOC:add]
synonym: "negative regulation of T lymphocyte differentiation" EXACT []
synonym: "negative regulation of T-cell differentiation" EXACT []
synonym: "negative regulation of T-lymphocyte differentiation" EXACT []
is_a: GO:0045580 ! regulation of T cell differentiation
is_a: GO:0045620 ! negative regulation of lymphocyte differentiation
is_a: GO:0050868 ! negative regulation of T cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030217 ! T cell differentiation
relationship: negatively_regulates GO:0030217 ! T cell differentiation

[Term]
id: GO:0045582
name: positive regulation of T cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of T cell differentiation." [GOC:go_curators]
comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
synonym: "activation of T cell differentiation" NARROW []
synonym: "positive regulation of T cell development" RELATED [GOC:add]
synonym: "positive regulation of T lymphocyte differentiation" EXACT []
synonym: "positive regulation of T-cell differentiation" EXACT []
synonym: "positive regulation of T-lymphocyte differentiation" EXACT []
synonym: "stimulation of T cell differentiation" NARROW []
synonym: "up regulation of T cell differentiation" EXACT []
synonym: "up-regulation of T cell differentiation" EXACT []
synonym: "upregulation of T cell differentiation" EXACT []
is_a: GO:0045580 ! regulation of T cell differentiation
is_a: GO:0045621 ! positive regulation of lymphocyte differentiation
is_a: GO:0050870 ! positive regulation of T cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030217 ! T cell differentiation
relationship: positively_regulates GO:0030217 ! T cell differentiation

[Term]
id: GO:0045595
name: regulation of cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." [GOC:go_curators]
is_a: GO:0050793 ! regulation of developmental process
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030154 ! cell differentiation
relationship: regulates GO:0030154 ! cell differentiation

[Term]
id: GO:0045596
name: negative regulation of cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." [GOC:go_curators]
synonym: "down regulation of cell differentiation" EXACT []
synonym: "down-regulation of cell differentiation" EXACT []
synonym: "downregulation of cell differentiation" EXACT []
synonym: "inhibition of cell differentiation" NARROW []
is_a: GO:0045595 ! regulation of cell differentiation
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051093 ! negative regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030154 ! cell differentiation
relationship: negatively_regulates GO:0030154 ! cell differentiation

[Term]
id: GO:0045597
name: positive regulation of cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell differentiation." [GOC:go_curators]
synonym: "activation of cell differentiation" NARROW []
synonym: "stimulation of cell differentiation" NARROW []
synonym: "up regulation of cell differentiation" EXACT []
synonym: "up-regulation of cell differentiation" EXACT []
synonym: "upregulation of cell differentiation" EXACT []
is_a: GO:0045595 ! regulation of cell differentiation
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051094 ! positive regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030154 ! cell differentiation
relationship: positively_regulates GO:0030154 ! cell differentiation

[Term]
id: GO:0045598
name: regulation of fat cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators]
synonym: "regulation of adipocyte cell differentiation" EXACT []
synonym: "regulation of adipocyte differentiation" EXACT []
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0045444 ! fat cell differentiation
relationship: regulates GO:0045444 ! fat cell differentiation

[Term]
id: GO:0045599
name: negative regulation of fat cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators]
synonym: "down regulation of fat cell differentiation" EXACT []
synonym: "down-regulation of fat cell differentiation" EXACT []
synonym: "downregulation of fat cell differentiation" EXACT []
synonym: "inhibition of fat cell differentiation" NARROW []
synonym: "negative regulation of adipocyte cell differentiation" EXACT []
synonym: "negative regulation of adipocyte differentiation" EXACT []
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0045598 ! regulation of fat cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045444 ! fat cell differentiation
relationship: negatively_regulates GO:0045444 ! fat cell differentiation

[Term]
id: GO:0045600
name: positive regulation of fat cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators]
synonym: "activation of fat cell differentiation" NARROW []
synonym: "positive regulation of adipocyte cell differentiation" EXACT []
synonym: "positive regulation of adipocyte differentiation" EXACT []
synonym: "stimulation of fat cell differentiation" NARROW []
synonym: "up regulation of fat cell differentiation" EXACT []
synonym: "up-regulation of fat cell differentiation" EXACT []
synonym: "upregulation of fat cell differentiation" EXACT []
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0045598 ! regulation of fat cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0045444 ! fat cell differentiation
relationship: positively_regulates GO:0045444 ! fat cell differentiation

[Term]
id: GO:0045601
name: regulation of endothelial cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators]
is_a: GO:0030856 ! regulation of epithelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0045446 ! endothelial cell differentiation
relationship: regulates GO:0045446 ! endothelial cell differentiation

[Term]
id: GO:0045602
name: negative regulation of endothelial cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators]
synonym: "down regulation of endothelial cell differentiation" EXACT []
synonym: "down-regulation of endothelial cell differentiation" EXACT []
synonym: "downregulation of endothelial cell differentiation" EXACT []
synonym: "inhibition of endothelial cell differentiation" NARROW []
is_a: GO:0030857 ! negative regulation of epithelial cell differentiation
is_a: GO:0045601 ! regulation of endothelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045446 ! endothelial cell differentiation
relationship: negatively_regulates GO:0045446 ! endothelial cell differentiation

[Term]
id: GO:0045603
name: positive regulation of endothelial cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators]
synonym: "activation of endothelial cell differentiation" NARROW []
synonym: "stimulation of endothelial cell differentiation" NARROW []
synonym: "up regulation of endothelial cell differentiation" EXACT []
synonym: "up-regulation of endothelial cell differentiation" EXACT []
synonym: "upregulation of endothelial cell differentiation" EXACT []
is_a: GO:0030858 ! positive regulation of epithelial cell differentiation
is_a: GO:0045601 ! regulation of endothelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0045446 ! endothelial cell differentiation
relationship: positively_regulates GO:0045446 ! endothelial cell differentiation

[Term]
id: GO:0045604
name: regulation of epidermal cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators]
synonym: "regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk]
is_a: GO:0030856 ! regulation of epithelial cell differentiation
is_a: GO:0045682 ! regulation of epidermis development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009913 ! epidermal cell differentiation
relationship: regulates GO:0009913 ! epidermal cell differentiation

[Term]
id: GO:0045605
name: negative regulation of epidermal cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators]
synonym: "down regulation of epidermal cell differentiation" EXACT []
synonym: "down-regulation of epidermal cell differentiation" EXACT []
synonym: "downregulation of epidermal cell differentiation" EXACT []
synonym: "inhibition of epidermal cell differentiation" NARROW []
synonym: "negative regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk]
is_a: GO:0030857 ! negative regulation of epithelial cell differentiation
is_a: GO:0045604 ! regulation of epidermal cell differentiation
is_a: GO:0045683 ! negative regulation of epidermis development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009913 ! epidermal cell differentiation
relationship: negatively_regulates GO:0009913 ! epidermal cell differentiation

[Term]
id: GO:0045606
name: positive regulation of epidermal cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators]
synonym: "activation of epidermal cell differentiation" NARROW []
synonym: "positive regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk]
synonym: "stimulation of epidermal cell differentiation" NARROW []
synonym: "up regulation of epidermal cell differentiation" EXACT []
synonym: "up-regulation of epidermal cell differentiation" EXACT []
synonym: "upregulation of epidermal cell differentiation" EXACT []
is_a: GO:0030858 ! positive regulation of epithelial cell differentiation
is_a: GO:0045604 ! regulation of epidermal cell differentiation
is_a: GO:0045684 ! positive regulation of epidermis development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009913 ! epidermal cell differentiation
relationship: positively_regulates GO:0009913 ! epidermal cell differentiation

[Term]
id: GO:0045619
name: regulation of lymphocyte differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators]
comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
synonym: "regulation of lymphocyte development" RELATED [GOC:add]
is_a: GO:0051249 ! regulation of lymphocyte activation
is_a: GO:1902105 ! regulation of leukocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030098 ! lymphocyte differentiation
relationship: regulates GO:0030098 ! lymphocyte differentiation

[Term]
id: GO:0045620
name: negative regulation of lymphocyte differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators]
comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
synonym: "down regulation of lymphocyte differentiation" EXACT []
synonym: "down-regulation of lymphocyte differentiation" EXACT []
synonym: "downregulation of lymphocyte differentiation" EXACT []
synonym: "inhibition of lymphocyte differentiation" NARROW []
synonym: "negative regulation of lymphocyte development" RELATED [GOC:add]
is_a: GO:0045619 ! regulation of lymphocyte differentiation
is_a: GO:0051250 ! negative regulation of lymphocyte activation
is_a: GO:1902106 ! negative regulation of leukocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030098 ! lymphocyte differentiation
relationship: negatively_regulates GO:0030098 ! lymphocyte differentiation

[Term]
id: GO:0045621
name: positive regulation of lymphocyte differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators]
comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
synonym: "activation of lymphocyte differentiation" NARROW []
synonym: "positive regulation of lymphocyte development" RELATED [GOC:add]
synonym: "stimulation of lymphocyte differentiation" NARROW []
synonym: "up regulation of lymphocyte differentiation" EXACT []
synonym: "up-regulation of lymphocyte differentiation" EXACT []
synonym: "upregulation of lymphocyte differentiation" EXACT []
is_a: GO:0045619 ! regulation of lymphocyte differentiation
is_a: GO:0051251 ! positive regulation of lymphocyte activation
is_a: GO:1902107 ! positive regulation of leukocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030098 ! lymphocyte differentiation
relationship: positively_regulates GO:0030098 ! lymphocyte differentiation

[Term]
id: GO:0045637
name: regulation of myeloid cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators]
is_a: GO:1903706 ! regulation of hemopoiesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030099 ! myeloid cell differentiation
relationship: regulates GO:0030099 ! myeloid cell differentiation

[Term]
id: GO:0045638
name: negative regulation of myeloid cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators]
synonym: "down regulation of myeloid cell differentiation" EXACT []
synonym: "down-regulation of myeloid cell differentiation" EXACT []
synonym: "downregulation of myeloid cell differentiation" EXACT []
synonym: "inhibition of myeloid cell differentiation" NARROW []
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0045637 ! regulation of myeloid cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030099 ! myeloid cell differentiation
relationship: negatively_regulates GO:0030099 ! myeloid cell differentiation

[Term]
id: GO:0045639
name: positive regulation of myeloid cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators]
synonym: "activation of myeloid cell differentiation" NARROW []
synonym: "stimulation of myeloid cell differentiation" NARROW []
synonym: "up regulation of myeloid cell differentiation" EXACT []
synonym: "up-regulation of myeloid cell differentiation" EXACT []
synonym: "upregulation of myeloid cell differentiation" EXACT []
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0045637 ! regulation of myeloid cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030099 ! myeloid cell differentiation
relationship: positively_regulates GO:0030099 ! myeloid cell differentiation

[Term]
id: GO:0045646
name: regulation of erythrocyte differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators]
synonym: "regulation of RBC differentiation" EXACT [CL:0000232]
synonym: "regulation of red blood cell differentiation" EXACT [CL:0000232]
is_a: GO:0045637 ! regulation of myeloid cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030218 ! erythrocyte differentiation
relationship: regulates GO:0030218 ! erythrocyte differentiation

[Term]
id: GO:0045647
name: negative regulation of erythrocyte differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators]
synonym: "down regulation of erythrocyte differentiation" EXACT []
synonym: "down-regulation of erythrocyte differentiation" EXACT []
synonym: "downregulation of erythrocyte differentiation" EXACT []
synonym: "inhibition of erythrocyte differentiation" NARROW []
synonym: "negative regulation of RBC differentiation" EXACT [CL:0000232]
synonym: "negative regulation of red blood cell differentiation" EXACT [CL:0000232]
is_a: GO:0045638 ! negative regulation of myeloid cell differentiation
is_a: GO:0045646 ! regulation of erythrocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030218 ! erythrocyte differentiation
relationship: negatively_regulates GO:0030218 ! erythrocyte differentiation

[Term]
id: GO:0045648
name: positive regulation of erythrocyte differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators]
synonym: "activation of erythrocyte differentiation" NARROW []
synonym: "positive regulation of RBC differentiation" EXACT [CL:0000232]
synonym: "positive regulation of red blood cell differentiation" EXACT [CL:0000232]
synonym: "stimulation of erythrocyte differentiation" NARROW []
synonym: "up regulation of erythrocyte differentiation" EXACT []
synonym: "up-regulation of erythrocyte differentiation" EXACT []
synonym: "upregulation of erythrocyte differentiation" EXACT []
is_a: GO:0045639 ! positive regulation of myeloid cell differentiation
is_a: GO:0045646 ! regulation of erythrocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030218 ! erythrocyte differentiation
relationship: positively_regulates GO:0030218 ! erythrocyte differentiation

[Term]
id: GO:0045652
name: regulation of megakaryocyte differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators]
is_a: GO:0045637 ! regulation of myeloid cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030219 ! megakaryocyte differentiation
relationship: regulates GO:0030219 ! megakaryocyte differentiation

[Term]
id: GO:0045653
name: negative regulation of megakaryocyte differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators]
synonym: "down regulation of megakaryocyte differentiation" EXACT []
synonym: "down-regulation of megakaryocyte differentiation" EXACT []
synonym: "downregulation of megakaryocyte differentiation" EXACT []
synonym: "inhibition of megakaryocyte differentiation" NARROW []
is_a: GO:0045638 ! negative regulation of myeloid cell differentiation
is_a: GO:0045652 ! regulation of megakaryocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030219 ! megakaryocyte differentiation
relationship: negatively_regulates GO:0030219 ! megakaryocyte differentiation

[Term]
id: GO:0045654
name: positive regulation of megakaryocyte differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators]
synonym: "activation of megakaryocyte differentiation" NARROW []
synonym: "stimulation of megakaryocyte differentiation" NARROW []
synonym: "up regulation of megakaryocyte differentiation" EXACT []
synonym: "up-regulation of megakaryocyte differentiation" EXACT []
synonym: "upregulation of megakaryocyte differentiation" EXACT []
is_a: GO:0045639 ! positive regulation of myeloid cell differentiation
is_a: GO:0045652 ! regulation of megakaryocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030219 ! megakaryocyte differentiation
relationship: positively_regulates GO:0030219 ! megakaryocyte differentiation

[Term]
id: GO:0045661
name: regulation of myoblast differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0045445 ! myoblast differentiation
relationship: regulates GO:0045445 ! myoblast differentiation

[Term]
id: GO:0045662
name: negative regulation of myoblast differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle]
synonym: "down regulation of myoblast differentiation" EXACT []
synonym: "down-regulation of myoblast differentiation" EXACT []
synonym: "downregulation of myoblast differentiation" EXACT []
synonym: "inhibition of myoblast differentiation" NARROW []
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0045661 ! regulation of myoblast differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045445 ! myoblast differentiation
relationship: negatively_regulates GO:0045445 ! myoblast differentiation

[Term]
id: GO:0045663
name: positive regulation of myoblast differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle]
synonym: "activation of myoblast differentiation" NARROW []
synonym: "stimulation of myoblast differentiation" NARROW []
synonym: "up regulation of myoblast differentiation" EXACT []
synonym: "up-regulation of myoblast differentiation" EXACT []
synonym: "upregulation of myoblast differentiation" EXACT []
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0045661 ! regulation of myoblast differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0045445 ! myoblast differentiation
relationship: positively_regulates GO:0045445 ! myoblast differentiation

[Term]
id: GO:0045664
name: regulation of neuron differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neuron differentiation." [GOC:go_curators]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030182 ! neuron differentiation
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: regulates GO:0030182 ! neuron differentiation

[Term]
id: GO:0045665
name: negative regulation of neuron differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." [GOC:go_curators]
synonym: "down regulation of neuron differentiation" EXACT []
synonym: "down-regulation of neuron differentiation" EXACT []
synonym: "downregulation of neuron differentiation" EXACT []
synonym: "inhibition of neuron differentiation" NARROW []
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0045664 ! regulation of neuron differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030182 ! neuron differentiation
relationship: negatively_regulates GO:0030182 ! neuron differentiation

[Term]
id: GO:0045666
name: positive regulation of neuron differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuron differentiation." [GOC:go_curators]
synonym: "activation of neuron differentiation" NARROW []
synonym: "stimulation of neuron differentiation" NARROW []
synonym: "up regulation of neuron differentiation" EXACT []
synonym: "up-regulation of neuron differentiation" EXACT []
synonym: "upregulation of neuron differentiation" EXACT []
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0045664 ! regulation of neuron differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030182 ! neuron differentiation
relationship: positively_regulates GO:0030182 ! neuron differentiation

[Term]
id: GO:0045682
name: regulation of epidermis development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of epidermis development." [GOC:go_curators]
synonym: "regulation of epidermal development" EXACT []
synonym: "regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008544 ! epidermis development
relationship: regulates GO:0008544 ! epidermis development

[Term]
id: GO:0045683
name: negative regulation of epidermis development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development." [GOC:go_curators]
synonym: "down regulation of epidermis development" EXACT []
synonym: "down-regulation of epidermis development" EXACT []
synonym: "downregulation of epidermis development" EXACT []
synonym: "inhibition of epidermis development" NARROW []
synonym: "negative regulation of epidermal development" EXACT []
synonym: "negative regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk]
is_a: GO:0045682 ! regulation of epidermis development
is_a: GO:0051093 ! negative regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008544 ! epidermis development
relationship: negatively_regulates GO:0008544 ! epidermis development

[Term]
id: GO:0045684
name: positive regulation of epidermis development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of epidermis development." [GOC:go_curators]
synonym: "activation of epidermis development" NARROW []
synonym: "positive regulation of epidermal development" EXACT []
synonym: "positive regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk]
synonym: "stimulation of epidermis development" NARROW []
synonym: "up regulation of epidermis development" EXACT []
synonym: "up-regulation of epidermis development" EXACT []
synonym: "upregulation of epidermis development" EXACT []
is_a: GO:0045682 ! regulation of epidermis development
is_a: GO:0051094 ! positive regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008544 ! epidermis development
relationship: positively_regulates GO:0008544 ! epidermis development

[Term]
id: GO:0045685
name: regulation of glial cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of glia cell differentiation." [GOC:go_curators]
synonym: "regulation of glia cell differentiation" EXACT []
synonym: "regulation of neuroglia differentiation" EXACT []
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010001 ! glial cell differentiation
relationship: regulates GO:0010001 ! glial cell differentiation

[Term]
id: GO:0045686
name: negative regulation of glial cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation." [GOC:go_curators]
synonym: "down regulation of glial cell differentiation" EXACT []
synonym: "down-regulation of glial cell differentiation" EXACT []
synonym: "downregulation of glial cell differentiation" EXACT []
synonym: "inhibition of glial cell differentiation" NARROW []
synonym: "negative regulation of glia cell differentiation" EXACT []
synonym: "negative regulation of neuroglia differentiation" EXACT []
is_a: GO:0014014 ! negative regulation of gliogenesis
is_a: GO:0045685 ! regulation of glial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010001 ! glial cell differentiation
relationship: negatively_regulates GO:0010001 ! glial cell differentiation

[Term]
id: GO:0045687
name: positive regulation of glial cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of glia cell differentiation." [GOC:go_curators]
synonym: "activation of glial cell differentiation" NARROW []
synonym: "positive regulation of glia cell differentiation" EXACT []
synonym: "positive regulation of neuroglia differentiation" EXACT []
synonym: "stimulation of glial cell differentiation" NARROW []
synonym: "up regulation of glial cell differentiation" EXACT []
synonym: "up-regulation of glial cell differentiation" EXACT []
synonym: "upregulation of glial cell differentiation" EXACT []
is_a: GO:0014015 ! positive regulation of gliogenesis
is_a: GO:0045685 ! regulation of glial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010001 ! glial cell differentiation
relationship: positively_regulates GO:0010001 ! glial cell differentiation

[Term]
id: GO:0045700
name: regulation of spermatid nuclear differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators]
is_a: GO:0051239 ! regulation of multicellular organismal process
is_a: GO:1903353 ! regulation of nucleus organization
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007289 ! spermatid nucleus differentiation
relationship: regulates GO:0007289 ! spermatid nucleus differentiation

[Term]
id: GO:0045701
name: negative regulation of spermatid nuclear differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators]
synonym: "down regulation of spermatid nuclear differentiation" EXACT []
synonym: "down-regulation of spermatid nuclear differentiation" EXACT []
synonym: "downregulation of spermatid nuclear differentiation" EXACT []
synonym: "inhibition of spermatid nuclear differentiation" NARROW []
is_a: GO:0010639 ! negative regulation of organelle organization
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0045700 ! regulation of spermatid nuclear differentiation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007289 ! spermatid nucleus differentiation
relationship: negatively_regulates GO:0007289 ! spermatid nucleus differentiation

[Term]
id: GO:0045702
name: positive regulation of spermatid nuclear differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators]
synonym: "activation of spermatid nuclear differentiation" NARROW []
synonym: "stimulation of spermatid nuclear differentiation" NARROW []
synonym: "up regulation of spermatid nuclear differentiation" EXACT []
synonym: "up-regulation of spermatid nuclear differentiation" EXACT []
synonym: "upregulation of spermatid nuclear differentiation" EXACT []
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0045700 ! regulation of spermatid nuclear differentiation
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007289 ! spermatid nucleus differentiation
relationship: positively_regulates GO:0007289 ! spermatid nucleus differentiation

[Term]
id: GO:0045719
name: negative regulation of glycogen biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators]
synonym: "down regulation of glycogen biosynthetic process" EXACT []
synonym: "down-regulation of glycogen biosynthetic process" EXACT []
synonym: "downregulation of glycogen biosynthetic process" EXACT []
synonym: "inhibition of glycogen biosynthetic process" NARROW []
synonym: "negative regulation of glycogen anabolism" EXACT []
synonym: "negative regulation of glycogen biosynthesis" EXACT []
synonym: "negative regulation of glycogen formation" EXACT []
synonym: "negative regulation of glycogen synthesis" EXACT []
is_a: GO:0005979 ! regulation of glycogen biosynthetic process
is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process
is_a: GO:0070874 ! negative regulation of glycogen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0005978 ! glycogen biosynthetic process
relationship: negatively_regulates GO:0005978 ! glycogen biosynthetic process

[Term]
id: GO:0045721
name: negative regulation of gluconeogenesis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis." [GOC:go_curators]
synonym: "down regulation of gluconeogenesis" EXACT []
synonym: "down-regulation of gluconeogenesis" EXACT []
synonym: "downregulation of gluconeogenesis" EXACT []
synonym: "inhibition of gluconeogenesis" NARROW []
is_a: GO:0006111 ! regulation of gluconeogenesis
is_a: GO:0031327 ! negative regulation of cellular biosynthetic process
is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006094 ! gluconeogenesis
relationship: negatively_regulates GO:0006094 ! gluconeogenesis

[Term]
id: GO:0045722
name: positive regulation of gluconeogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of gluconeogenesis." [GOC:go_curators]
synonym: "activation of gluconeogenesis" NARROW []
synonym: "stimulation of gluconeogenesis" NARROW []
synonym: "up regulation of gluconeogenesis" EXACT []
synonym: "up-regulation of gluconeogenesis" EXACT []
synonym: "upregulation of gluconeogenesis" EXACT []
is_a: GO:0006111 ! regulation of gluconeogenesis
is_a: GO:0010907 ! positive regulation of glucose metabolic process
is_a: GO:0031328 ! positive regulation of cellular biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006094 ! gluconeogenesis
relationship: positively_regulates GO:0006094 ! gluconeogenesis

[Term]
id: GO:0045724
name: positive regulation of cilium assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the formation of a cilium." [GOC:cilia, GOC:go_curators]
synonym: "activation of cilium assembly" NARROW []
synonym: "positive regulation of flagellum assembly" BROAD []
synonym: "positive regulation of flagellum biogenesis" RELATED [GOC:mah]
synonym: "stimulation of cilium assembly" NARROW []
synonym: "up regulation of cilium assembly" EXACT []
synonym: "up-regulation of cilium assembly" EXACT []
synonym: "upregulation of cilium assembly" EXACT []
is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly
is_a: GO:1902017 ! regulation of cilium assembly
is_a: GO:1902117 ! positive regulation of organelle assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060271 ! cilium assembly
relationship: positively_regulates GO:0060271 ! cilium assembly

[Term]
id: GO:0045725
name: positive regulation of glycogen biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators]
synonym: "activation of glycogen biosynthetic process" NARROW []
synonym: "positive regulation of glycogen anabolism" EXACT []
synonym: "positive regulation of glycogen biosynthesis" EXACT []
synonym: "positive regulation of glycogen formation" EXACT []
synonym: "positive regulation of glycogen synthesis" EXACT []
synonym: "stimulation of glycogen biosynthetic process" NARROW []
synonym: "up regulation of glycogen biosynthetic process" EXACT []
synonym: "up-regulation of glycogen biosynthetic process" EXACT []
synonym: "upregulation of glycogen biosynthetic process" EXACT []
is_a: GO:0005979 ! regulation of glycogen biosynthetic process
is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process
is_a: GO:0070875 ! positive regulation of glycogen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0005978 ! glycogen biosynthetic process
relationship: positively_regulates GO:0005978 ! glycogen biosynthetic process

[Term]
id: GO:0045727
name: positive regulation of translation
namespace: biological_process
alt_id: GO:0045946
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "activation of protein biosynthetic process" NARROW []
synonym: "positive regulation of protein anabolism" EXACT []
synonym: "positive regulation of protein biosynthesis" EXACT []
synonym: "positive regulation of protein biosynthetic process" EXACT [GOC:tb]
synonym: "positive regulation of protein formation" EXACT []
synonym: "positive regulation of protein synthesis" EXACT []
synonym: "stimulation of protein biosynthetic process" NARROW []
synonym: "up regulation of protein biosynthetic process" EXACT []
synonym: "up-regulation of protein biosynthetic process" EXACT []
synonym: "upregulation of protein biosynthetic process" EXACT []
is_a: GO:0006417 ! regulation of translation
is_a: GO:0010628 ! positive regulation of gene expression
is_a: GO:0034250 ! positive regulation of amide metabolic process
is_a: GO:0051247 ! positive regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006412 ! translation
relationship: positively_regulates GO:0006412 ! translation

[Term]
id: GO:0045732
name: positive regulation of protein catabolic process
namespace: biological_process
alt_id: GO:1903364
alt_id: GO:2000600
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators]
synonym: "activation of cellular protein breakdown" NARROW [GOC:TermGenie]
synonym: "activation of cellular protein catabolic process" NARROW [GOC:TermGenie]
synonym: "activation of cellular protein catabolism" NARROW [GOC:TermGenie]
synonym: "activation of cellular protein degradation" NARROW [GOC:TermGenie]
synonym: "activation of protein catabolic process" NARROW []
synonym: "positive regulation of cellular protein breakdown" EXACT [GOC:TermGenie]
synonym: "positive regulation of cellular protein catabolic process" EXACT []
synonym: "positive regulation of cellular protein catabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of cellular protein degradation" EXACT [GOC:TermGenie]
synonym: "positive regulation of cyclin breakdown" NARROW [GOC:obol]
synonym: "positive regulation of cyclin catabolic process" NARROW []
synonym: "positive regulation of cyclin catabolism" NARROW [GOC:obol]
synonym: "positive regulation of cyclin degradation" NARROW [GOC:obol]
synonym: "positive regulation of degradation of cyclin" NARROW [GOC:obol]
synonym: "positive regulation of protein breakdown" EXACT []
synonym: "positive regulation of protein catabolism" EXACT []
synonym: "positive regulation of protein degradation" EXACT []
synonym: "stimulation of protein catabolic process" NARROW []
synonym: "up regulation of cellular protein breakdown" EXACT [GOC:TermGenie]
synonym: "up regulation of cellular protein catabolic process" EXACT [GOC:TermGenie]
synonym: "up regulation of cellular protein catabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of cellular protein degradation" EXACT [GOC:TermGenie]
synonym: "up regulation of protein catabolic process" EXACT []
synonym: "up-regulation of cellular protein breakdown" EXACT [GOC:TermGenie]
synonym: "up-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of cellular protein catabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of cellular protein degradation" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein catabolic process" EXACT []
synonym: "upregulation of cellular protein breakdown" EXACT [GOC:TermGenie]
synonym: "upregulation of cellular protein catabolic process" EXACT [GOC:TermGenie]
synonym: "upregulation of cellular protein catabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of cellular protein degradation" EXACT [GOC:TermGenie]
synonym: "upregulation of protein catabolic process" EXACT []
is_a: GO:0009896 ! positive regulation of catabolic process
is_a: GO:0042176 ! regulation of protein catabolic process
is_a: GO:0051247 ! positive regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030163 ! protein catabolic process
relationship: positively_regulates GO:0030163 ! protein catabolic process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI

[Term]
id: GO:0045733
name: acetate catabolic process
namespace: biological_process
alt_id: GO:0019663
def: "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators]
synonym: "acetate breakdown" EXACT []
synonym: "acetate catabolism" EXACT []
synonym: "acetate degradation" EXACT []
synonym: "homoacetate catabolic process" RELATED []
is_a: GO:0006083 ! acetate metabolic process
is_a: GO:0072329 ! monocarboxylic acid catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:30089 ! acetate
relationship: has_primary_input CHEBI:30089 ! acetate

[Term]
id: GO:0045734
name: regulation of acetate catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators]
synonym: "regulation of acetate breakdown" EXACT []
synonym: "regulation of acetate catabolism" EXACT []
synonym: "regulation of acetate degradation" EXACT []
is_a: GO:0010565 ! regulation of cellular ketone metabolic process
is_a: GO:0031329 ! regulation of cellular catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0045733 ! acetate catabolic process
relationship: regulates GO:0045733 ! acetate catabolic process

[Term]
id: GO:0045753
name: negative regulation of acetate catabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators]
synonym: "down regulation of acetate catabolic process" EXACT []
synonym: "down-regulation of acetate catabolic process" EXACT []
synonym: "downregulation of acetate catabolic process" EXACT []
synonym: "inhibition of acetate catabolic process" NARROW []
synonym: "negative regulation of acetate breakdown" EXACT []
synonym: "negative regulation of acetate catabolism" EXACT []
synonym: "negative regulation of acetate degradation" EXACT []
is_a: GO:0031330 ! negative regulation of cellular catabolic process
is_a: GO:0045734 ! regulation of acetate catabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045733 ! acetate catabolic process
relationship: negatively_regulates GO:0045733 ! acetate catabolic process

[Term]
id: GO:0045754
name: positive regulation of acetate catabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators]
synonym: "activation of acetate catabolic process" NARROW []
synonym: "positive regulation of acetate breakdown" EXACT []
synonym: "positive regulation of acetate catabolism" EXACT []
synonym: "positive regulation of acetate degradation" EXACT []
synonym: "stimulation of acetate catabolic process" NARROW []
synonym: "up regulation of acetate catabolic process" EXACT []
synonym: "up-regulation of acetate catabolic process" EXACT []
synonym: "upregulation of acetate catabolic process" EXACT []
is_a: GO:0031331 ! positive regulation of cellular catabolic process
is_a: GO:0045734 ! regulation of acetate catabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0045733 ! acetate catabolic process
relationship: positively_regulates GO:0045733 ! acetate catabolic process

[Term]
id: GO:0045759
name: negative regulation of action potential
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators]
synonym: "down regulation of action potential" EXACT []
synonym: "down-regulation of action potential" EXACT []
synonym: "downregulation of action potential" EXACT []
synonym: "inhibition of action potential" NARROW []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0098900 ! regulation of action potential
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001508 ! action potential
relationship: negatively_regulates GO:0001508 ! action potential

[Term]
id: GO:0045760
name: positive regulation of action potential
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators]
synonym: "activation of action potential" NARROW []
synonym: "stimulation of action potential" NARROW []
synonym: "up regulation of action potential" EXACT []
synonym: "up-regulation of action potential" EXACT []
synonym: "upregulation of action potential" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0098900 ! regulation of action potential
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001508 ! action potential
relationship: positively_regulates GO:0001508 ! action potential

[Term]
id: GO:0045763
name: negative regulation of cellular amino acid metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators]
synonym: "down regulation of amino acid metabolic process" EXACT []
synonym: "down-regulation of amino acid metabolic process" EXACT []
synonym: "downregulation of amino acid metabolic process" EXACT []
synonym: "inhibition of amino acid metabolic process" NARROW []
synonym: "negative regulation of amino acid metabolism" EXACT []
is_a: GO:0006521 ! regulation of cellular amino acid metabolic process
is_a: GO:0033239 ! negative regulation of amine metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006520 ! amino acid metabolic process
relationship: negatively_regulates GO:0006520 ! amino acid metabolic process

[Term]
id: GO:0045764
name: positive regulation of amino acid metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators]
synonym: "activation of amino acid metabolic process" NARROW []
synonym: "positive regulation of amino acid metabolism" EXACT []
synonym: "positive regulation of cellular amino acid metabolic process" EXACT []
synonym: "stimulation of amino acid metabolic process" NARROW []
synonym: "up regulation of amino acid metabolic process" EXACT []
synonym: "up-regulation of amino acid metabolic process" EXACT []
synonym: "upregulation of amino acid metabolic process" EXACT []
is_a: GO:0006521 ! regulation of cellular amino acid metabolic process
is_a: GO:0033240 ! positive regulation of amine metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006520 ! amino acid metabolic process
relationship: positively_regulates GO:0006520 ! amino acid metabolic process

[Term]
id: GO:0045765
name: regulation of angiogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of angiogenesis." [GOC:go_curators]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
is_a: GO:1901342 ! regulation of vasculature development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001525 ! angiogenesis
relationship: regulates GO:0001525 ! angiogenesis

[Term]
id: GO:0045766
name: positive regulation of angiogenesis
namespace: biological_process
def: "Any process that activates or increases angiogenesis." [GOC:go_curators]
synonym: "activation of angiogenesis" NARROW []
synonym: "stimulation of angiogenesis" NARROW []
synonym: "up regulation of angiogenesis" EXACT []
synonym: "up-regulation of angiogenesis" EXACT []
synonym: "upregulation of angiogenesis" EXACT []
is_a: GO:0045765 ! regulation of angiogenesis
is_a: GO:1904018 ! positive regulation of vasculature development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001525 ! angiogenesis
relationship: positively_regulates GO:0001525 ! angiogenesis

[Term]
id: GO:0045769
name: negative regulation of asymmetric cell division
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division." [GOC:go_curators]
synonym: "down regulation of asymmetric cell division" EXACT []
synonym: "down-regulation of asymmetric cell division" EXACT []
synonym: "downregulation of asymmetric cell division" EXACT []
synonym: "inhibition of asymmetric cell division" NARROW []
is_a: GO:0009786 ! regulation of asymmetric cell division
is_a: GO:0051782 ! negative regulation of cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008356 ! asymmetric cell division
relationship: negatively_regulates GO:0008356 ! asymmetric cell division

[Term]
id: GO:0045770
name: positive regulation of asymmetric cell division
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." [GOC:go_curators]
synonym: "activation of asymmetric cell division" NARROW []
synonym: "stimulation of asymmetric cell division" NARROW []
synonym: "up regulation of asymmetric cell division" EXACT []
synonym: "up-regulation of asymmetric cell division" EXACT []
synonym: "upregulation of asymmetric cell division" EXACT []
is_a: GO:0009786 ! regulation of asymmetric cell division
is_a: GO:0051781 ! positive regulation of cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008356 ! asymmetric cell division
relationship: positively_regulates GO:0008356 ! asymmetric cell division

[Term]
id: GO:0045778
name: positive regulation of ossification
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators]
synonym: "activation of ossification" NARROW []
synonym: "positive regulation of bone biosynthesis" EXACT []
synonym: "positive regulation of bone formation" EXACT []
synonym: "stimulation of ossification" NARROW []
synonym: "up regulation of ossification" EXACT []
synonym: "up-regulation of ossification" EXACT []
synonym: "upregulation of ossification" EXACT []
is_a: GO:0030278 ! regulation of ossification
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001503 ! ossification
relationship: positively_regulates GO:0001503 ! ossification

[Term]
id: GO:0045785
name: positive regulation of cell adhesion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell adhesion." [GOC:go_curators]
synonym: "activation of cell adhesion" NARROW []
synonym: "stimulation of cell adhesion" NARROW []
synonym: "up regulation of cell adhesion" EXACT []
synonym: "up-regulation of cell adhesion" EXACT []
synonym: "upregulation of cell adhesion" EXACT []
is_a: GO:0030155 ! regulation of cell adhesion
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007155 ! cell adhesion
relationship: positively_regulates GO:0007155 ! cell adhesion

[Term]
id: GO:0045786
name: negative regulation of cell cycle
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "down regulation of progression through cell cycle" EXACT []
synonym: "down-regulation of progression through cell cycle" EXACT []
synonym: "downregulation of progression through cell cycle" EXACT []
synonym: "inhibition of progression through cell cycle" NARROW []
synonym: "negative regulation of cell cycle progression" EXACT []
synonym: "negative regulation of progression through cell cycle" EXACT []
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051726 ! regulation of cell cycle
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007049 ! cell cycle
relationship: negatively_regulates GO:0007049 ! cell cycle

[Term]
id: GO:0045787
name: positive regulation of cell cycle
namespace: biological_process
def: "Any process that activates or increases the rate or extent of progression through the cell cycle." [GOC:go_curators]
synonym: "activation of progression through cell cycle" NARROW []
synonym: "positive regulation of cell cycle progression" EXACT []
synonym: "positive regulation of progression through cell cycle" EXACT [GOC:dph, GOC:tb]
synonym: "stimulation of progression through cell cycle" NARROW []
synonym: "up regulation of progression through cell cycle" EXACT []
synonym: "up-regulation of progression through cell cycle" EXACT []
synonym: "upregulation of progression through cell cycle" EXACT []
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051726 ! regulation of cell cycle
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007049 ! cell cycle
relationship: positively_regulates GO:0007049 ! cell cycle

[Term]
id: GO:0045806
name: negative regulation of endocytosis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis." [GOC:go_curators]
synonym: "down regulation of endocytosis" EXACT []
synonym: "down-regulation of endocytosis" EXACT []
synonym: "downregulation of endocytosis" EXACT []
synonym: "inhibition of endocytosis" NARROW []
is_a: GO:0030100 ! regulation of endocytosis
is_a: GO:0051051 ! negative regulation of transport
is_a: GO:0051129 ! negative regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006897 ! endocytosis
relationship: negatively_regulates GO:0006897 ! endocytosis

[Term]
id: GO:0045807
name: positive regulation of endocytosis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of endocytosis." [GOC:go_curators]
synonym: "activation of endocytosis" NARROW []
synonym: "stimulation of endocytosis" NARROW []
synonym: "up regulation of endocytosis" EXACT []
synonym: "up-regulation of endocytosis" EXACT []
synonym: "upregulation of endocytosis" EXACT []
is_a: GO:0030100 ! regulation of endocytosis
is_a: GO:0051050 ! positive regulation of transport
is_a: GO:0051130 ! positive regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006897 ! endocytosis
relationship: positively_regulates GO:0006897 ! endocytosis

[Term]
id: GO:0045818
name: negative regulation of glycogen catabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators]
synonym: "down regulation of glycogen catabolic process" EXACT []
synonym: "down-regulation of glycogen catabolic process" EXACT []
synonym: "downregulation of glycogen catabolic process" EXACT []
synonym: "inhibition of glycogen catabolic process" NARROW []
synonym: "negative regulation of glycogen breakdown" EXACT []
synonym: "negative regulation of glycogen catabolism" EXACT []
synonym: "negative regulation of glycogen degradation" EXACT []
synonym: "negative regulation of glycogenolysis" EXACT [GOC:sl]
is_a: GO:0005981 ! regulation of glycogen catabolic process
is_a: GO:0031330 ! negative regulation of cellular catabolic process
is_a: GO:0070874 ! negative regulation of glycogen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0005980 ! glycogen catabolic process
relationship: negatively_regulates GO:0005980 ! glycogen catabolic process

[Term]
id: GO:0045819
name: positive regulation of glycogen catabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators]
synonym: "activation of glycogen catabolic process" NARROW []
synonym: "positive regulation of glycogen breakdown" EXACT []
synonym: "positive regulation of glycogen catabolism" EXACT []
synonym: "positive regulation of glycogen degradation" EXACT []
synonym: "positive regulation of glycogenolysis" EXACT [GOC:sl]
synonym: "stimulation of glycogen catabolic process" NARROW []
synonym: "up regulation of glycogen catabolic process" EXACT []
synonym: "up-regulation of glycogen catabolic process" EXACT []
synonym: "upregulation of glycogen catabolic process" EXACT []
is_a: GO:0005981 ! regulation of glycogen catabolic process
is_a: GO:0031331 ! positive regulation of cellular catabolic process
is_a: GO:0070875 ! positive regulation of glycogen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0005980 ! glycogen catabolic process
relationship: positively_regulates GO:0005980 ! glycogen catabolic process

[Term]
id: GO:0045822
name: negative regulation of heart contraction
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction." [GOC:go_curators]
synonym: "down regulation of heart contraction" EXACT []
synonym: "down-regulation of heart contraction" EXACT []
synonym: "downregulation of heart contraction" EXACT []
synonym: "inhibition of heart contraction" NARROW []
synonym: "negative regulation of cardiac contraction" RELATED []
is_a: GO:0008016 ! regulation of heart contraction
is_a: GO:1903523 ! negative regulation of blood circulation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060047 ! heart contraction
relationship: negatively_regulates GO:0060047 ! heart contraction

[Term]
id: GO:0045823
name: positive regulation of heart contraction
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of heart contraction." [GOC:go_curators]
synonym: "activation of heart contraction" NARROW []
synonym: "positive regulation of cardiac contraction" EXACT []
synonym: "stimulation of heart contraction" NARROW []
synonym: "up regulation of heart contraction" EXACT []
synonym: "up-regulation of heart contraction" EXACT []
synonym: "upregulation of heart contraction" EXACT []
is_a: GO:0008016 ! regulation of heart contraction
is_a: GO:1903524 ! positive regulation of blood circulation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060047 ! heart contraction
relationship: positively_regulates GO:0060047 ! heart contraction

[Term]
id: GO:0045833
name: negative regulation of lipid metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators]
synonym: "down regulation of lipid metabolic process" EXACT []
synonym: "down-regulation of lipid metabolic process" EXACT []
synonym: "downregulation of lipid metabolic process" EXACT []
synonym: "inhibition of lipid metabolic process" NARROW []
synonym: "negative regulation of lipid metabolism" EXACT []
is_a: GO:0009892 ! negative regulation of metabolic process
is_a: GO:0019216 ! regulation of lipid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006629 ! lipid metabolic process
relationship: negatively_regulates GO:0006629 ! lipid metabolic process

[Term]
id: GO:0045834
name: positive regulation of lipid metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators]
synonym: "activation of lipid metabolic process" NARROW []
synonym: "positive regulation of lipid metabolism" EXACT []
synonym: "stimulation of lipid metabolic process" NARROW []
synonym: "up regulation of lipid metabolic process" EXACT []
synonym: "up-regulation of lipid metabolic process" EXACT []
synonym: "upregulation of lipid metabolic process" EXACT []
is_a: GO:0009893 ! positive regulation of metabolic process
is_a: GO:0019216 ! regulation of lipid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006629 ! lipid metabolic process
relationship: positively_regulates GO:0006629 ! lipid metabolic process

[Term]
id: GO:0045835
name: negative regulation of meiotic nuclear division
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis." [GOC:go_curators]
synonym: "down regulation of meiosis" EXACT []
synonym: "down-regulation of meiosis" EXACT []
synonym: "downregulation of meiosis" EXACT []
synonym: "inhibition of meiosis" NARROW []
synonym: "negative regulation of meiosis" EXACT []
is_a: GO:0010948 ! negative regulation of cell cycle process
is_a: GO:0040020 ! regulation of meiotic nuclear division
is_a: GO:0051447 ! negative regulation of meiotic cell cycle
is_a: GO:0051784 ! negative regulation of nuclear division
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0140013 ! meiotic nuclear division
relationship: negatively_regulates GO:0140013 ! meiotic nuclear division

[Term]
id: GO:0045836
name: positive regulation of meiotic nuclear division
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of meiosis." [GOC:go_curators]
synonym: "activation of meiosis" NARROW []
synonym: "positive regulation of meiosis" EXACT []
synonym: "stimulation of meiosis" NARROW []
synonym: "up regulation of meiosis" EXACT []
synonym: "up-regulation of meiosis" EXACT []
synonym: "upregulation of meiosis" EXACT []
is_a: GO:0040020 ! regulation of meiotic nuclear division
is_a: GO:0051446 ! positive regulation of meiotic cell cycle
is_a: GO:0051785 ! positive regulation of nuclear division
is_a: GO:0090068 ! positive regulation of cell cycle process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0140013 ! meiotic nuclear division
relationship: positively_regulates GO:0140013 ! meiotic nuclear division

[Term]
id: GO:0045839
name: negative regulation of mitotic nuclear division
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "down regulation of mitosis" EXACT []
synonym: "down-regulation of mitosis" EXACT []
synonym: "downregulation of mitosis" EXACT []
synonym: "inhibition of mitosis" NARROW []
synonym: "negative regulation of mitosis" EXACT []
is_a: GO:0007088 ! regulation of mitotic nuclear division
is_a: GO:0010948 ! negative regulation of cell cycle process
is_a: GO:0045930 ! negative regulation of mitotic cell cycle
is_a: GO:0051784 ! negative regulation of nuclear division
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0140014 ! mitotic nuclear division
relationship: negatively_regulates GO:0140014 ! mitotic nuclear division

[Term]
id: GO:0045840
name: positive regulation of mitotic nuclear division
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mitosis." [GOC:go_curators]
synonym: "activation of mitosis" NARROW []
synonym: "mitogenic activity" NARROW []
synonym: "positive regulation of mitosis" EXACT []
synonym: "stimulation of mitosis" NARROW []
synonym: "up regulation of mitosis" EXACT []
synonym: "up-regulation of mitosis" EXACT []
synonym: "upregulation of mitosis" EXACT []
is_a: GO:0007088 ! regulation of mitotic nuclear division
is_a: GO:0051785 ! positive regulation of nuclear division
is_a: GO:0090068 ! positive regulation of cell cycle process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0140014 ! mitotic nuclear division
relationship: positively_regulates GO:0140014 ! mitotic nuclear division

[Term]
id: GO:0045843
name: negative regulation of striated muscle tissue development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development." [GOC:go_curators]
synonym: "down regulation of striated muscle development" EXACT []
synonym: "down-regulation of striated muscle development" EXACT []
synonym: "downregulation of striated muscle development" EXACT []
synonym: "inhibition of striated muscle development" NARROW []
is_a: GO:0016202 ! regulation of striated muscle tissue development
is_a: GO:0048635 ! negative regulation of muscle organ development
is_a: GO:1901862 ! negative regulation of muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014706 ! striated muscle tissue development
relationship: negatively_regulates GO:0014706 ! striated muscle tissue development

[Term]
id: GO:0045844
name: positive regulation of striated muscle tissue development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of striated muscle development." [GOC:go_curators]
synonym: "activation of striated muscle development" NARROW []
synonym: "stimulation of striated muscle development" NARROW []
synonym: "up regulation of striated muscle development" EXACT []
synonym: "up-regulation of striated muscle development" EXACT []
synonym: "upregulation of striated muscle development" EXACT []
is_a: GO:0016202 ! regulation of striated muscle tissue development
is_a: GO:0048636 ! positive regulation of muscle organ development
is_a: GO:1901863 ! positive regulation of muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014706 ! striated muscle tissue development
relationship: positively_regulates GO:0014706 ! striated muscle tissue development

[Term]
id: GO:0045900
name: negative regulation of translational elongation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation." [GOC:go_curators]
synonym: "down regulation of translational elongation" EXACT []
synonym: "down-regulation of translational elongation" EXACT []
synonym: "downregulation of translational elongation" EXACT []
synonym: "inhibition of translational elongation" NARROW []
is_a: GO:0006448 ! regulation of translational elongation
is_a: GO:0017148 ! negative regulation of translation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006414 ! translational elongation
relationship: negatively_regulates GO:0006414 ! translational elongation

[Term]
id: GO:0045901
name: positive regulation of translational elongation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of translational elongation." [GOC:go_curators]
synonym: "activation of translational elongation" NARROW []
synonym: "stimulation of translational elongation" NARROW []
synonym: "up regulation of translational elongation" EXACT []
synonym: "up-regulation of translational elongation" EXACT []
synonym: "upregulation of translational elongation" EXACT []
is_a: GO:0006448 ! regulation of translational elongation
is_a: GO:0045727 ! positive regulation of translation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006414 ! translational elongation
relationship: positively_regulates GO:0006414 ! translational elongation

[Term]
id: GO:0045904
name: negative regulation of translational termination
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination." [GOC:go_curators]
synonym: "down regulation of translational termination" EXACT []
synonym: "down-regulation of translational termination" EXACT []
synonym: "downregulation of translational termination" EXACT []
synonym: "inhibition of translational termination" NARROW []
is_a: GO:0006449 ! regulation of translational termination
is_a: GO:0017148 ! negative regulation of translation
is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006415 ! translational termination
relationship: negatively_regulates GO:0006415 ! translational termination

[Term]
id: GO:0045905
name: positive regulation of translational termination
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of translational termination." [GOC:go_curators]
synonym: "activation of translational termination" NARROW []
synonym: "stimulation of translational termination" NARROW []
synonym: "up regulation of translational termination" EXACT []
synonym: "up-regulation of translational termination" EXACT []
synonym: "upregulation of translational termination" EXACT []
is_a: GO:0006449 ! regulation of translational termination
is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly
is_a: GO:0045727 ! positive regulation of translation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006415 ! translational termination
relationship: positively_regulates GO:0006415 ! translational termination

[Term]
id: GO:0045912
name: negative regulation of carbohydrate metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators]
synonym: "down regulation of carbohydrate metabolic process" EXACT []
synonym: "down-regulation of carbohydrate metabolic process" EXACT []
synonym: "downregulation of carbohydrate metabolic process" EXACT []
synonym: "inhibition of carbohydrate metabolic process" NARROW []
synonym: "negative regulation of carbohydrate metabolism" EXACT []
is_a: GO:0006109 ! regulation of carbohydrate metabolic process
is_a: GO:0009892 ! negative regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0005975 ! carbohydrate metabolic process
relationship: negatively_regulates GO:0005975 ! carbohydrate metabolic process

[Term]
id: GO:0045913
name: positive regulation of carbohydrate metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators]
synonym: "activation of carbohydrate metabolic process" NARROW []
synonym: "positive regulation of carbohydrate metabolism" EXACT []
synonym: "stimulation of carbohydrate metabolic process" NARROW []
synonym: "up regulation of carbohydrate metabolic process" EXACT []
synonym: "up-regulation of carbohydrate metabolic process" EXACT []
synonym: "upregulation of carbohydrate metabolic process" EXACT []
is_a: GO:0006109 ! regulation of carbohydrate metabolic process
is_a: GO:0009893 ! positive regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0005975 ! carbohydrate metabolic process
relationship: positively_regulates GO:0005975 ! carbohydrate metabolic process

[Term]
id: GO:0045914
name: negative regulation of catecholamine metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators]
synonym: "down regulation of catecholamine metabolic process" EXACT []
synonym: "down-regulation of catecholamine metabolic process" EXACT []
synonym: "downregulation of catecholamine metabolic process" EXACT []
synonym: "inhibition of catecholamine metabolic process" NARROW []
synonym: "negative regulation of catecholamine metabolism" EXACT []
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0033239 ! negative regulation of amine metabolic process
is_a: GO:0042069 ! regulation of catecholamine metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006584 ! catecholamine metabolic process
relationship: negatively_regulates GO:0006584 ! catecholamine metabolic process

[Term]
id: GO:0045915
name: positive regulation of catecholamine metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators]
synonym: "activation of catecholamine metabolic process" NARROW []
synonym: "positive regulation of catecholamine metabolism" EXACT []
synonym: "stimulation of catecholamine metabolic process" NARROW []
synonym: "up regulation of catecholamine metabolic process" EXACT []
synonym: "up-regulation of catecholamine metabolic process" EXACT []
synonym: "upregulation of catecholamine metabolic process" EXACT []
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0033240 ! positive regulation of amine metabolic process
is_a: GO:0042069 ! regulation of catecholamine metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006584 ! catecholamine metabolic process
relationship: positively_regulates GO:0006584 ! catecholamine metabolic process

[Term]
id: GO:0045920
name: negative regulation of exocytosis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis." [GOC:go_curators]
synonym: "down regulation of exocytosis" EXACT []
synonym: "down-regulation of exocytosis" EXACT []
synonym: "downregulation of exocytosis" EXACT []
synonym: "inhibition of exocytosis" NARROW []
is_a: GO:0017157 ! regulation of exocytosis
is_a: GO:1903531 ! negative regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006887 ! exocytosis
relationship: negatively_regulates GO:0006887 ! exocytosis

[Term]
id: GO:0045921
name: positive regulation of exocytosis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of exocytosis." [GOC:go_curators]
synonym: "activation of exocytosis" NARROW []
synonym: "stimulation of exocytosis" NARROW []
synonym: "up regulation of exocytosis" EXACT []
synonym: "up-regulation of exocytosis" EXACT []
synonym: "upregulation of exocytosis" EXACT []
is_a: GO:0017157 ! regulation of exocytosis
is_a: GO:1903532 ! positive regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006887 ! exocytosis
relationship: positively_regulates GO:0006887 ! exocytosis

[Term]
id: GO:0045926
name: negative regulation of growth
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators]
synonym: "down regulation of growth" EXACT []
synonym: "down-regulation of growth" EXACT []
synonym: "downregulation of growth" EXACT []
synonym: "inhibition of growth" NARROW []
is_a: GO:0040008 ! regulation of growth
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0040007 ! growth
relationship: negatively_regulates GO:0040007 ! growth

[Term]
id: GO:0045927
name: positive regulation of growth
namespace: biological_process
def: "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators]
synonym: "activation of growth" NARROW []
synonym: "stimulation of growth" NARROW []
synonym: "up regulation of growth" EXACT []
synonym: "up-regulation of growth" EXACT []
synonym: "upregulation of growth" EXACT []
is_a: GO:0040008 ! regulation of growth
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0040007 ! growth
relationship: positively_regulates GO:0040007 ! growth

[Term]
id: GO:0045930
name: negative regulation of mitotic cell cycle
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "down regulation of progression through mitotic cell cycle" EXACT []
synonym: "down-regulation of progression through mitotic cell cycle" EXACT []
synonym: "downregulation of progression through mitotic cell cycle" EXACT []
synonym: "inhibition of progression through mitotic cell cycle" NARROW []
synonym: "negative regulation of mitotic cell cycle progression" EXACT []
synonym: "negative regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb]
is_a: GO:0007346 ! regulation of mitotic cell cycle
is_a: GO:0045786 ! negative regulation of cell cycle
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0000278 ! mitotic cell cycle
relationship: negatively_regulates GO:0000278 ! mitotic cell cycle

[Term]
id: GO:0045931
name: positive regulation of mitotic cell cycle
namespace: biological_process
def: "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb]
synonym: "activation of progression through mitotic cell cycle" NARROW []
synonym: "positive regulation of mitotic cell cycle progression" EXACT []
synonym: "positive regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb]
synonym: "stimulation of progression through mitotic cell cycle" NARROW []
synonym: "up regulation of progression through mitotic cell cycle" EXACT []
synonym: "up-regulation of progression through mitotic cell cycle" EXACT []
synonym: "upregulation of progression through mitotic cell cycle" EXACT []
is_a: GO:0007346 ! regulation of mitotic cell cycle
is_a: GO:0045787 ! positive regulation of cell cycle
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0000278 ! mitotic cell cycle
relationship: positively_regulates GO:0000278 ! mitotic cell cycle

[Term]
id: GO:0045932
name: negative regulation of muscle contraction
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction." [GOC:go_curators]
synonym: "down regulation of muscle contraction" EXACT []
synonym: "down-regulation of muscle contraction" EXACT []
synonym: "downregulation of muscle contraction" EXACT []
synonym: "inhibition of muscle contraction" NARROW []
is_a: GO:0006937 ! regulation of muscle contraction
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006936 ! muscle contraction
relationship: negatively_regulates GO:0006936 ! muscle contraction

[Term]
id: GO:0045933
name: positive regulation of muscle contraction
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of muscle contraction." [GOC:go_curators]
synonym: "activation of muscle contraction" NARROW []
synonym: "stimulation of muscle contraction" NARROW []
synonym: "up regulation of muscle contraction" EXACT []
synonym: "up-regulation of muscle contraction" EXACT []
synonym: "upregulation of muscle contraction" EXACT []
is_a: GO:0006937 ! regulation of muscle contraction
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006936 ! muscle contraction
relationship: positively_regulates GO:0006936 ! muscle contraction

[Term]
id: GO:0045934
name: negative regulation of nucleobase-containing compound metabolic process
namespace: biological_process
def: "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators]
synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT []
synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT []
synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT []
synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW []
synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb]
synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT []
is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006139 ! nucleobase-containing compound metabolic process
relationship: negatively_regulates GO:0006139 ! nucleobase-containing compound metabolic process

[Term]
id: GO:0045935
name: positive regulation of nucleobase-containing compound metabolic process
namespace: biological_process
def: "Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators]
synonym: "activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW []
synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb]
synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT []
synonym: "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW []
synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT []
synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT []
synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT []
is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006139 ! nucleobase-containing compound metabolic process
relationship: positively_regulates GO:0006139 ! nucleobase-containing compound metabolic process

[Term]
id: GO:0045936
name: negative regulation of phosphate metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators]
synonym: "down regulation of phosphate metabolic process" EXACT []
synonym: "down-regulation of phosphate metabolic process" EXACT []
synonym: "downregulation of phosphate metabolic process" EXACT []
synonym: "inhibition of phosphate metabolic process" NARROW []
synonym: "negative regulation of phosphate metabolism" EXACT []
is_a: GO:0010563 ! negative regulation of phosphorus metabolic process
is_a: GO:0019220 ! regulation of phosphate metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process
relationship: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process

[Term]
id: GO:0045937
name: positive regulation of phosphate metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators]
synonym: "activation of phosphate metabolic process" NARROW []
synonym: "positive regulation of phosphate metabolism" EXACT []
synonym: "stimulation of phosphate metabolic process" NARROW []
synonym: "up regulation of phosphate metabolic process" EXACT []
synonym: "up-regulation of phosphate metabolic process" EXACT []
synonym: "upregulation of phosphate metabolic process" EXACT []
is_a: GO:0010562 ! positive regulation of phosphorus metabolic process
is_a: GO:0019220 ! regulation of phosphate metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process
relationship: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process

[Term]
id: GO:0045939
name: negative regulation of steroid metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators]
synonym: "down regulation of steroid metabolic process" EXACT []
synonym: "down-regulation of steroid metabolic process" EXACT []
synonym: "downregulation of steroid metabolic process" EXACT []
synonym: "inhibition of steroid metabolic process" NARROW []
synonym: "negative regulation of steroid metabolism" EXACT []
is_a: GO:0019218 ! regulation of steroid metabolic process
is_a: GO:0045833 ! negative regulation of lipid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008202 ! steroid metabolic process
relationship: negatively_regulates GO:0008202 ! steroid metabolic process

[Term]
id: GO:0045940
name: positive regulation of steroid metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators]
synonym: "activation of steroid metabolic process" NARROW []
synonym: "positive regulation of steroid metabolism" EXACT []
synonym: "stimulation of steroid metabolic process" NARROW []
synonym: "up regulation of steroid metabolic process" EXACT []
synonym: "up-regulation of steroid metabolic process" EXACT []
synonym: "upregulation of steroid metabolic process" EXACT []
is_a: GO:0019218 ! regulation of steroid metabolic process
is_a: GO:0045834 ! positive regulation of lipid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008202 ! steroid metabolic process
relationship: positively_regulates GO:0008202 ! steroid metabolic process

[Term]
id: GO:0045947
name: negative regulation of translational initiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation." [GOC:go_curators]
synonym: "down regulation of translational initiation" EXACT []
synonym: "down-regulation of translational initiation" EXACT []
synonym: "downregulation of translational initiation" EXACT []
synonym: "inhibition of translational initiation" NARROW []
is_a: GO:0006446 ! regulation of translational initiation
is_a: GO:0017148 ! negative regulation of translation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006413 ! translational initiation
relationship: negatively_regulates GO:0006413 ! translational initiation

[Term]
id: GO:0045948
name: positive regulation of translational initiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of translational initiation." [GOC:go_curators]
synonym: "activation of translational initiation" NARROW []
synonym: "stimulation of translational initiation" NARROW []
synonym: "up regulation of translational initiation" EXACT []
synonym: "up-regulation of translational initiation" EXACT []
synonym: "upregulation of translational initiation" EXACT []
is_a: GO:0006446 ! regulation of translational initiation
is_a: GO:0045727 ! positive regulation of translation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006413 ! translational initiation
relationship: positively_regulates GO:0006413 ! translational initiation

[Term]
id: GO:0045986
name: negative regulation of smooth muscle contraction
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators]
synonym: "down regulation of smooth muscle contraction" EXACT []
synonym: "down-regulation of smooth muscle contraction" EXACT []
synonym: "downregulation of smooth muscle contraction" EXACT []
synonym: "inhibition of smooth muscle contraction" NARROW []
synonym: "smooth muscle relaxation" RELATED []
is_a: GO:0006940 ! regulation of smooth muscle contraction
is_a: GO:0045932 ! negative regulation of muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006939 ! smooth muscle contraction
relationship: negatively_regulates GO:0006939 ! smooth muscle contraction

[Term]
id: GO:0045987
name: positive regulation of smooth muscle contraction
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators]
synonym: "activation of smooth muscle contraction" NARROW []
synonym: "stimulation of smooth muscle contraction" NARROW []
synonym: "up regulation of smooth muscle contraction" EXACT []
synonym: "up-regulation of smooth muscle contraction" EXACT []
synonym: "upregulation of smooth muscle contraction" EXACT []
is_a: GO:0006940 ! regulation of smooth muscle contraction
is_a: GO:0045933 ! positive regulation of muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006939 ! smooth muscle contraction
relationship: positively_regulates GO:0006939 ! smooth muscle contraction

[Term]
id: GO:0045988
name: negative regulation of striated muscle contraction
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction." [GOC:go_curators]
synonym: "down regulation of striated muscle contraction" EXACT []
synonym: "down-regulation of striated muscle contraction" EXACT []
synonym: "downregulation of striated muscle contraction" EXACT []
synonym: "inhibition of striated muscle contraction" NARROW []
is_a: GO:0006942 ! regulation of striated muscle contraction
is_a: GO:0045932 ! negative regulation of muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006941 ! striated muscle contraction
relationship: negatively_regulates GO:0006941 ! striated muscle contraction

[Term]
id: GO:0045989
name: positive regulation of striated muscle contraction
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of striated muscle contraction." [GOC:go_curators]
synonym: "activation of striated muscle contraction" NARROW []
synonym: "stimulation of striated muscle contraction" NARROW []
synonym: "up regulation of striated muscle contraction" EXACT []
synonym: "up-regulation of striated muscle contraction" EXACT []
synonym: "upregulation of striated muscle contraction" EXACT []
is_a: GO:0006942 ! regulation of striated muscle contraction
is_a: GO:0045933 ! positive regulation of muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006941 ! striated muscle contraction
relationship: positively_regulates GO:0006941 ! striated muscle contraction

[Term]
id: GO:0045992
name: negative regulation of embryonic development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." [GOC:go_curators]
synonym: "down regulation of embryonic development" EXACT []
synonym: "down-regulation of embryonic development" EXACT []
synonym: "downregulation of embryonic development" EXACT []
synonym: "inhibition of embryonic development" NARROW []
is_a: GO:0045995 ! regulation of embryonic development
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009790 ! embryo development
relationship: negatively_regulates GO:0009790 ! embryo development

[Term]
id: GO:0045995
name: regulation of embryonic development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of embryonic development." [GOC:go_curators]
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009790 ! embryo development
relationship: regulates GO:0009790 ! embryo development

[Term]
id: GO:0046013
name: regulation of T cell homeostatic proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of resting T cell proliferation." [GOC:go_curators]
synonym: "regulation of resting T cell proliferation" EXACT []
synonym: "regulation of T lymphocyte homeostatic proliferation" EXACT []
synonym: "regulation of T-cell homeostatic proliferation" EXACT []
synonym: "regulation of T-lymphocyte homeostatic proliferation" EXACT []
is_a: GO:0042129 ! regulation of T cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001777 ! T cell homeostatic proliferation
relationship: regulates GO:0001777 ! T cell homeostatic proliferation

[Term]
id: GO:0046014
name: negative regulation of T cell homeostatic proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation." [GOC:go_curators]
synonym: "down regulation of T cell homeostatic proliferation" EXACT []
synonym: "down-regulation of T cell homeostatic proliferation" EXACT []
synonym: "downregulation of T cell homeostatic proliferation" EXACT []
synonym: "inhibition of T cell homeostatic proliferation" NARROW []
synonym: "negative regulation of resting T cell proliferation" EXACT []
synonym: "negative regulation of T lymphocyte homeostatic proliferation" EXACT []
synonym: "negative regulation of T-cell homeostatic proliferation" EXACT []
synonym: "negative regulation of T-lymphocyte homeostatic proliferation" EXACT []
is_a: GO:0042130 ! negative regulation of T cell proliferation
is_a: GO:0046013 ! regulation of T cell homeostatic proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001777 ! T cell homeostatic proliferation
relationship: negatively_regulates GO:0001777 ! T cell homeostatic proliferation

[Term]
id: GO:0046112
name: nucleobase biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai]
synonym: "nucleobase anabolism" EXACT []
synonym: "nucleobase biosynthesis" EXACT []
synonym: "nucleobase formation" EXACT []
synonym: "nucleobase synthesis" EXACT []
is_a: GO:0009112 ! nucleobase metabolic process
is_a: GO:0018130 ! heterocycle biosynthetic process
is_a: GO:1901362 ! organic cyclic compound biosynthetic process
is_a: GO:1901566 ! organonitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:18282 ! nucleobase
relationship: has_primary_output CHEBI:18282 ! nucleobase

[Term]
id: GO:0046113
name: nucleobase catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai]
synonym: "nucleobase breakdown" EXACT []
synonym: "nucleobase catabolism" EXACT []
synonym: "nucleobase degradation" EXACT []
is_a: GO:0009112 ! nucleobase metabolic process
is_a: GO:0046700 ! heterocycle catabolic process
is_a: GO:1901361 ! organic cyclic compound catabolic process
is_a: GO:1901565 ! organonitrogen compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:18282 ! nucleobase
relationship: has_primary_input CHEBI:18282 ! nucleobase

[Term]
id: GO:0046189
name: phenol-containing compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [GOC:ai]
synonym: "phenol-containing compound anabolism" EXACT []
synonym: "phenol-containing compound biosynthesis" EXACT []
synonym: "phenol-containing compound formation" EXACT []
synonym: "phenol-containing compound synthesis" EXACT []
is_a: GO:0018958 ! phenol-containing compound metabolic process
is_a: GO:0019438 ! aromatic compound biosynthetic process
is_a: GO:1901362 ! organic cyclic compound biosynthetic process
is_a: GO:1901617 ! organic hydroxy compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:33853 ! phenols
relationship: has_primary_output CHEBI:33853 ! phenols

[Term]
id: GO:0046219
name: indolalkylamine biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators]
synonym: "indolalkylamine anabolism" EXACT []
synonym: "indolalkylamine biosynthesis" EXACT []
synonym: "indolalkylamine formation" EXACT []
synonym: "indolalkylamine synthesis" EXACT []
is_a: GO:0006586 ! indolalkylamine metabolic process
is_a: GO:0042401 ! biogenic amine biosynthetic process
is_a: GO:0042435 ! indole-containing compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:38631 ! aminoalkylindole
relationship: has_primary_output CHEBI:38631 ! aminoalkylindole

[Term]
id: GO:0046348
name: amino sugar catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:curators]
synonym: "amino sugar breakdown" EXACT []
synonym: "amino sugar catabolism" EXACT []
synonym: "amino sugar degradation" EXACT []
synonym: "aminosaccharide catabolic process" EXACT []
synonym: "aminosaccharide catabolism" EXACT []
is_a: GO:0006040 ! amino sugar metabolic process
is_a: GO:1901136 ! carbohydrate derivative catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:28963 ! amino sugar
relationship: has_primary_input CHEBI:28963 ! amino sugar

[Term]
id: GO:0046349
name: amino sugar biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group." [GOC:curators]
synonym: "amino sugar anabolism" EXACT []
synonym: "amino sugar biosynthesis" EXACT []
synonym: "amino sugar formation" EXACT []
synonym: "amino sugar synthesis" EXACT []
synonym: "aminosaccharide biosynthesis" EXACT []
synonym: "aminosaccharide biosynthetic process" EXACT []
is_a: GO:0006040 ! amino sugar metabolic process
is_a: GO:1901137 ! carbohydrate derivative biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:28963 ! amino sugar
relationship: has_primary_output CHEBI:28963 ! amino sugar

[Term]
id: GO:0046364
name: monosaccharide biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732]
synonym: "monosaccharide anabolism" EXACT []
synonym: "monosaccharide biosynthesis" EXACT []
synonym: "monosaccharide formation" EXACT []
synonym: "monosaccharide synthesis" EXACT []
is_a: GO:0005996 ! monosaccharide metabolic process
is_a: GO:0016051 ! carbohydrate biosynthetic process
is_a: GO:0044283 ! small molecule biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:35381 ! monosaccharide
relationship: has_primary_output CHEBI:35381 ! monosaccharide

[Term]
id: GO:0046365
name: monosaccharide catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732]
synonym: "monosaccharide breakdown" EXACT []
synonym: "monosaccharide catabolism" EXACT []
synonym: "monosaccharide degradation" EXACT []
is_a: GO:0005996 ! monosaccharide metabolic process
is_a: GO:0016052 ! carbohydrate catabolic process
is_a: GO:0044282 ! small molecule catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:35381 ! monosaccharide
relationship: has_primary_input CHEBI:35381 ! monosaccharide

[Term]
id: GO:0046394
name: carboxylic acid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732]
synonym: "carboxylic acid anabolism" EXACT []
synonym: "carboxylic acid biosynthesis" EXACT []
synonym: "carboxylic acid formation" EXACT []
synonym: "carboxylic acid synthesis" EXACT []
is_a: GO:0016053 ! organic acid biosynthetic process
is_a: GO:0019752 ! carboxylic acid metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:29067 ! carboxylic acid anion
relationship: has_primary_output CHEBI:29067 ! carboxylic acid anion

[Term]
id: GO:0046395
name: carboxylic acid catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732]
synonym: "carboxylic acid breakdown" EXACT []
synonym: "carboxylic acid catabolism" EXACT []
synonym: "carboxylic acid degradation" EXACT []
is_a: GO:0016054 ! organic acid catabolic process
is_a: GO:0019752 ! carboxylic acid metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion
relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion

[Term]
id: GO:0046483
name: heterocycle metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198506732]
subset: goslim_pir
synonym: "heterocycle metabolism" EXACT []
is_a: GO:0044237 ! cellular metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:5686 ! heterocyclic compound
relationship: has_primary_input_or_output CHEBI:5686 ! heterocyclic compound

[Term]
id: GO:0046530
name: photoreceptor cell differentiation
namespace: biological_process
alt_id: GO:0007467
def: "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster." [GOC:ai, ISBN:0198506732]
is_a: GO:0030182 ! neuron differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000210 ! photoreceptor cell
relationship: results_in_acquisition_of_features_of CL:0000210 ! photoreceptor cell

[Term]
id: GO:0046532
name: regulation of photoreceptor cell differentiation
namespace: biological_process
alt_id: GO:0045673
def: "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators]
synonym: "regulation of photoreceptor differentiation" EXACT []
is_a: GO:0045664 ! regulation of neuron differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0046530 ! photoreceptor cell differentiation
relationship: regulates GO:0046530 ! photoreceptor cell differentiation

[Term]
id: GO:0046533
name: negative regulation of photoreceptor cell differentiation
namespace: biological_process
alt_id: GO:0045674
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators]
synonym: "down regulation of photoreceptor cell differentiation" EXACT []
synonym: "down regulation of photoreceptor differentiation" EXACT []
synonym: "down-regulation of photoreceptor cell differentiation" EXACT []
synonym: "down-regulation of photoreceptor differentiation" EXACT []
synonym: "downregulation of photoreceptor cell differentiation" EXACT []
synonym: "downregulation of photoreceptor differentiation" EXACT []
synonym: "inhibition of photoreceptor cell differentiation" NARROW []
synonym: "inhibition of photoreceptor differentiation" NARROW []
synonym: "negative regulation of photoreceptor differentiation" EXACT []
is_a: GO:0045665 ! negative regulation of neuron differentiation
is_a: GO:0046532 ! regulation of photoreceptor cell differentiation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0046530 ! photoreceptor cell differentiation
relationship: negatively_regulates GO:0046530 ! photoreceptor cell differentiation

[Term]
id: GO:0046534
name: positive regulation of photoreceptor cell differentiation
namespace: biological_process
alt_id: GO:0045675
def: "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators]
synonym: "activation of photoreceptor cell differentiation" NARROW []
synonym: "activation of photoreceptor differentiation" NARROW []
synonym: "positive regulation of photoreceptor differentiation" EXACT []
synonym: "stimulation of photoreceptor cell differentiation" NARROW []
synonym: "stimulation of photoreceptor differentiation" NARROW []
synonym: "up regulation of photoreceptor cell differentiation" EXACT []
synonym: "up regulation of photoreceptor differentiation" EXACT []
synonym: "up-regulation of photoreceptor cell differentiation" EXACT []
synonym: "up-regulation of photoreceptor differentiation" EXACT []
synonym: "upregulation of photoreceptor cell differentiation" EXACT []
synonym: "upregulation of photoreceptor differentiation" EXACT []
is_a: GO:0045666 ! positive regulation of neuron differentiation
is_a: GO:0046532 ! regulation of photoreceptor cell differentiation
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0046530 ! photoreceptor cell differentiation
relationship: positively_regulates GO:0046530 ! photoreceptor cell differentiation

[Term]
id: GO:0046545
name: development of primary female sexual characteristics
namespace: biological_process
def: "The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion." [GOC:ai]
is_a: GO:0045137 ! development of primary sexual characteristics
relationship: part_of GO:0046660 ! female sex differentiation

[Term]
id: GO:0046546
name: development of primary male sexual characteristics
namespace: biological_process
def: "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion." [GOC:ai]
is_a: GO:0045137 ! development of primary sexual characteristics
relationship: part_of GO:0046661 ! male sex differentiation

[Term]
id: GO:0046548
name: retinal rod cell development
namespace: biological_process
def: "Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light." [ISBN:0198506732]
is_a: GO:0042462 ! eye photoreceptor cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000604 ! retinal rod cell
relationship: part_of GO:0060221 ! retinal rod cell differentiation
relationship: results_in_development_of CL:0000604 ! retinal rod cell

[Term]
id: GO:0046549
name: retinal cone cell development
namespace: biological_process
def: "Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision." [ISBN:0198506732]
is_a: GO:0042462 ! eye photoreceptor cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000573 ! retinal cone cell
relationship: part_of GO:0042670 ! retinal cone cell differentiation
relationship: results_in_development_of CL:0000573 ! retinal cone cell

[Term]
id: GO:0046620
name: regulation of organ growth
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb]
is_a: GO:0048638 ! regulation of developmental growth
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035265 ! organ growth
relationship: regulates GO:0035265 ! organ growth

[Term]
id: GO:0046621
name: negative regulation of organ growth
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb]
is_a: GO:0046620 ! regulation of organ growth
is_a: GO:0048640 ! negative regulation of developmental growth
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035265 ! organ growth
relationship: negatively_regulates GO:0035265 ! organ growth

[Term]
id: GO:0046622
name: positive regulation of organ growth
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb]
is_a: GO:0046620 ! regulation of organ growth
is_a: GO:0048639 ! positive regulation of developmental growth
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035265 ! organ growth
relationship: positively_regulates GO:0035265 ! organ growth

[Term]
id: GO:0046649
name: lymphocyte activation
namespace: biological_process
def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149]
is_a: GO:0045321 ! leukocyte activation
intersection_of: GO:0001775 ! cell activation
intersection_of: has_primary_input CL:0000542 ! lymphocyte
relationship: has_primary_input CL:0000542 ! lymphocyte

[Term]
id: GO:0046651
name: lymphocyte proliferation
namespace: biological_process
def: "The expansion of a lymphocyte population by cell division." [GOC:ai]
is_a: GO:0032943 ! mononuclear cell proliferation
is_a: GO:0046649 ! lymphocyte activation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000542 ! lymphocyte
relationship: acts_on_population_of CL:0000542 ! lymphocyte

[Term]
id: GO:0046660
name: female sex differentiation
namespace: biological_process
def: "The establishment of the sex of a female organism by physical differentiation." [GOC:bf]
is_a: GO:0007548 ! sex differentiation
relationship: part_of GO:0007275 ! multicellular organism development

[Term]
id: GO:0046661
name: male sex differentiation
namespace: biological_process
def: "The establishment of the sex of a male organism by physical differentiation." [GOC:bf]
is_a: GO:0007548 ! sex differentiation
relationship: part_of GO:0007275 ! multicellular organism development

[Term]
id: GO:0046666
name: retinal cell programmed cell death
namespace: biological_process
def: "Programmed cell death that occurs in the developing retina." [GOC:bf]
synonym: "programmed cell death, retina cells" EXACT []
synonym: "programmed cell death, retinal cells" EXACT []
synonym: "retina cell programmed cell death" EXACT []
synonym: "retina programmed cell death" EXACT []
synonym: "retinal programmed cell death" EXACT []
is_a: GO:0010623 ! programmed cell death involved in cell development
relationship: part_of GO:0048592 ! eye morphogenesis

[Term]
id: GO:0046667
name: compound eye retinal cell programmed cell death
namespace: biological_process
def: "Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium." [PMID:12006672]
is_a: GO:0046666 ! retinal cell programmed cell death
intersection_of: GO:0046666 ! retinal cell programmed cell death
intersection_of: results_in_maturation_of UBERON:0000018 ! compound eye
relationship: part_of GO:0001745 ! compound eye morphogenesis
relationship: results_in_maturation_of UBERON:0000018 ! compound eye

[Term]
id: GO:0046668
name: regulation of retinal cell programmed cell death
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb]
synonym: "regulation of retinal programmed cell death" EXACT [GOC:tb]
is_a: GO:0043067 ! regulation of programmed cell death
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0046666 ! retinal cell programmed cell death
relationship: regulates GO:0046666 ! retinal cell programmed cell death

[Term]
id: GO:0046669
name: regulation of compound eye retinal cell programmed cell death
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai]
synonym: "regulation of retinal cell programmed cell death" BROAD []
is_a: GO:0046668 ! regulation of retinal cell programmed cell death
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0046667 ! compound eye retinal cell programmed cell death
relationship: regulates GO:0046667 ! compound eye retinal cell programmed cell death

[Term]
id: GO:0046670
name: positive regulation of retinal cell programmed cell death
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb]
synonym: "activation of retinal programmed cell death" NARROW []
synonym: "positive regulation of retinal programmed cell death" EXACT [GOC:tb]
synonym: "stimulation of retinal programmed cell death" NARROW []
synonym: "up regulation of retinal programmed cell death" EXACT []
synonym: "up-regulation of retinal programmed cell death" EXACT []
synonym: "upregulation of retinal programmed cell death" EXACT []
is_a: GO:0043068 ! positive regulation of programmed cell death
is_a: GO:0046668 ! regulation of retinal cell programmed cell death
is_a: GO:0051094 ! positive regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0046666 ! retinal cell programmed cell death
relationship: positively_regulates GO:0046666 ! retinal cell programmed cell death

[Term]
id: GO:0046671
name: negative regulation of retinal cell programmed cell death
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb]
synonym: "down regulation of retinal programmed cell death" EXACT []
synonym: "down-regulation of retinal programmed cell death" EXACT []
synonym: "downregulation of retinal programmed cell death" EXACT []
synonym: "inhibition of retinal programmed cell death" NARROW []
synonym: "negative regulation of retinal programmed cell death" EXACT [GOC:tb]
is_a: GO:0043069 ! negative regulation of programmed cell death
is_a: GO:0046668 ! regulation of retinal cell programmed cell death
is_a: GO:0051093 ! negative regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0046666 ! retinal cell programmed cell death
relationship: negatively_regulates GO:0046666 ! retinal cell programmed cell death

[Term]
id: GO:0046672
name: positive regulation of compound eye retinal cell programmed cell death
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai]
synonym: "activation of retinal cell programmed cell death" BROAD []
synonym: "positive regulation of retinal cell programmed cell death" BROAD []
synonym: "stimulation of retinal cell programmed cell death" BROAD []
synonym: "up regulation of retinal cell programmed cell death" BROAD []
synonym: "up-regulation of retinal cell programmed cell death" BROAD []
synonym: "upregulation of retinal cell programmed cell death" BROAD []
is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death
is_a: GO:0046670 ! positive regulation of retinal cell programmed cell death
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0046667 ! compound eye retinal cell programmed cell death
relationship: positively_regulates GO:0046667 ! compound eye retinal cell programmed cell death

[Term]
id: GO:0046673
name: negative regulation of compound eye retinal cell programmed cell death
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai]
synonym: "down regulation of retinal cell programmed cell death" BROAD []
synonym: "down-regulation of retinal cell programmed cell death" BROAD []
synonym: "downregulation of retinal cell programmed cell death" BROAD []
synonym: "inhibition of retinal cell programmed cell death" BROAD []
synonym: "negative regulation of retina cell programmed cell death" BROAD []
synonym: "negative regulation of retinal cell programmed cell death" BROAD []
is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death
is_a: GO:0046671 ! negative regulation of retinal cell programmed cell death
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0046667 ! compound eye retinal cell programmed cell death
relationship: negatively_regulates GO:0046667 ! compound eye retinal cell programmed cell death

[Term]
id: GO:0046676
name: negative regulation of insulin secretion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin." [GOC:ai]
synonym: "down regulation of insulin secretion" EXACT []
synonym: "down-regulation of insulin secretion" EXACT []
synonym: "downregulation of insulin secretion" EXACT []
synonym: "inhibition of insulin secretion" NARROW []
is_a: GO:0050709 ! negative regulation of protein secretion
is_a: GO:0050796 ! regulation of insulin secretion
is_a: GO:0090278 ! negative regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030073 ! insulin secretion
relationship: negatively_regulates GO:0030073 ! insulin secretion

[Term]
id: GO:0046681
name: response to carbamate
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase." [ISBN:0721662544]
synonym: "carbamate resistance" RELATED []
synonym: "carbamate susceptibility/resistance" RELATED []
is_a: GO:0010243 ! response to organonitrogen compound
is_a: GO:0017085 ! response to insecticide
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:13941 ! carbamate
relationship: has_primary_input CHEBI:13941 ! carbamate

[Term]
id: GO:0046700
name: heterocycle catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [GOC:ai]
synonym: "heterocycle breakdown" EXACT []
synonym: "heterocycle catabolism" EXACT []
synonym: "heterocycle degradation" EXACT []
is_a: GO:0044248 ! cellular catabolic process
is_a: GO:0046483 ! heterocycle metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:5686 ! heterocyclic compound
relationship: has_primary_input CHEBI:5686 ! heterocyclic compound

[Term]
id: GO:0046716
name: muscle cell cellular homeostasis
namespace: biological_process
def: "The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state." [GOC:mah, PMID:3091429, PMID:7781901]
synonym: "muscle fiber maintenance" NARROW [GOC:dph, GOC:tb]
synonym: "muscle homeostasis" RELATED [GOC:dph]
is_a: GO:0019725 ! cellular homeostasis
intersection_of: GO:0019725 ! cellular homeostasis
intersection_of: occurs_in CL:0000187 ! muscle cell
relationship: occurs_in CL:0000187 ! muscle cell
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0046717
name: acid secretion
namespace: biological_process
def: "The controlled release of acid by a cell or a tissue." [GOC:ai]
is_a: GO:0046903 ! secretion

[Term]
id: GO:0046785
name: microtubule polymerization
namespace: biological_process
def: "The addition of tubulin heterodimers to one or both ends of a microtubule." [GOC:ai, GOC:go_curators]
synonym: "microtubule assembly" EXACT []
synonym: "microtubule formation" RELATED []
is_a: GO:0031109 ! microtubule polymerization or depolymerization
is_a: GO:0051258 ! protein polymerization
is_a: GO:0097435 ! supramolecular fiber organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0005874 ! microtubule
relationship: results_in_assembly_of GO:0005874 ! microtubule
relationship: starts_with GO:0007020 ! microtubule nucleation

[Term]
id: GO:0046873
name: metal ion transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of metal ions from one side of a membrane to the other." [GOC:ai]
synonym: "heavy metal ion porter activity" NARROW []
synonym: "heavy metal ion transporter activity" NARROW []
synonym: "heavy metal ion:hydrogen symporter activity" NARROW []
synonym: "heavy metal-exporting ATPase activity" NARROW []
synonym: "high affinity metal ion uptake transporter activity" NARROW []
synonym: "low affinity metal ion uptake transporter activity" NARROW []
is_a: GO:0008324 ! monoatomic cation transmembrane transporter activity
is_a: GO:0022890 ! inorganic cation transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:25213 ! metal cation
relationship: has_primary_input CHEBI:25213 ! metal cation
relationship: part_of GO:0030001 ! metal ion transport

[Term]
id: GO:0046879
name: hormone secretion
namespace: biological_process
def: "The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells." [ISBN:0198506732]
is_a: GO:0009914 ! hormone transport
is_a: GO:0023061 ! signal release

[Term]
id: GO:0046883
name: regulation of hormone secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0010817 ! regulation of hormone levels
is_a: GO:0023051 ! regulation of signaling
is_a: GO:1903530 ! regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0046879 ! hormone secretion
relationship: regulates GO:0046879 ! hormone secretion

[Term]
id: GO:0046887
name: positive regulation of hormone secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai]
synonym: "activation of hormone secretion" NARROW []
synonym: "stimulation of hormone secretion" NARROW []
synonym: "up regulation of hormone secretion" EXACT []
synonym: "up-regulation of hormone secretion" EXACT []
synonym: "upregulation of hormone secretion" EXACT []
is_a: GO:0010647 ! positive regulation of cell communication
is_a: GO:0023056 ! positive regulation of signaling
is_a: GO:0046883 ! regulation of hormone secretion
is_a: GO:1903532 ! positive regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0046879 ! hormone secretion
relationship: positively_regulates GO:0046879 ! hormone secretion

[Term]
id: GO:0046888
name: negative regulation of hormone secretion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai]
synonym: "down regulation of hormone secretion" EXACT []
synonym: "down-regulation of hormone secretion" EXACT []
synonym: "downregulation of hormone secretion" EXACT []
synonym: "inhibition of hormone secretion" NARROW []
is_a: GO:0010648 ! negative regulation of cell communication
is_a: GO:0023057 ! negative regulation of signaling
is_a: GO:0046883 ! regulation of hormone secretion
is_a: GO:1903531 ! negative regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0046879 ! hormone secretion
relationship: negatively_regulates GO:0046879 ! hormone secretion

[Term]
id: GO:0046889
name: positive regulation of lipid biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai]
synonym: "activation of lipid biosynthetic process" NARROW []
synonym: "positive regulation of lipid anabolism" EXACT []
synonym: "positive regulation of lipid biosynthesis" EXACT []
synonym: "positive regulation of lipid formation" EXACT []
synonym: "positive regulation of lipid synthesis" EXACT []
synonym: "positive regulation of lipogenesis" EXACT [GOC:sl]
synonym: "stimulation of lipid biosynthetic process" NARROW []
synonym: "up regulation of lipid biosynthetic process" EXACT []
synonym: "up-regulation of lipid biosynthetic process" EXACT []
synonym: "upregulation of lipid biosynthetic process" EXACT []
is_a: GO:0009891 ! positive regulation of biosynthetic process
is_a: GO:0045834 ! positive regulation of lipid metabolic process
is_a: GO:0046890 ! regulation of lipid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008610 ! lipid biosynthetic process
relationship: positively_regulates GO:0008610 ! lipid biosynthetic process

[Term]
id: GO:0046890
name: regulation of lipid biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai]
synonym: "regulation of lipid anabolism" EXACT []
synonym: "regulation of lipid biosynthesis" EXACT []
synonym: "regulation of lipid formation" EXACT []
synonym: "regulation of lipid synthesis" EXACT []
synonym: "regulation of lipogenesis" EXACT [GOC:sl]
is_a: GO:0009889 ! regulation of biosynthetic process
is_a: GO:0019216 ! regulation of lipid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008610 ! lipid biosynthetic process
relationship: regulates GO:0008610 ! lipid biosynthetic process

[Term]
id: GO:0046903
name: secretion
namespace: biological_process
def: "The controlled release of a substance by a cell or a tissue." [GOC:ai]
subset: goslim_pir
is_a: GO:0006810 ! transport

[Term]
id: GO:0046907
name: intracellular transport
namespace: biological_process
alt_id: GO:1902582
def: "The directed movement of substances within a cell." [GOC:ai]
synonym: "single organism intracellular transport" RELATED [GOC:TermGenie]
synonym: "single-organism intracellular transport" RELATED []
is_a: GO:0006810 ! transport
is_a: GO:0051641 ! cellular localization
is_a: GO:0051649 ! establishment of localization in cell
intersection_of: GO:0006810 ! transport
intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure
relationship: occurs_in GO:0005622 ! intracellular anatomical structure
created_by: jl
creation_date: 2013-12-18T14:04:50Z

[Term]
id: GO:0046928
name: regulation of neurotransmitter secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell." [GOC:ai]
is_a: GO:0050804 ! modulation of chemical synaptic transmission
is_a: GO:0051588 ! regulation of neurotransmitter transport
is_a: GO:1903530 ! regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007269 ! neurotransmitter secretion
relationship: regulates GO:0007269 ! neurotransmitter secretion

[Term]
id: GO:0046929
name: negative regulation of neurotransmitter secretion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:ai]
synonym: "conotoxin activity" NARROW []
synonym: "down regulation of neurotransmitter secretion" EXACT []
synonym: "down-regulation of neurotransmitter secretion" EXACT []
synonym: "downregulation of neurotransmitter secretion" EXACT []
synonym: "inhibition of neurotransmitter secretion" NARROW []
is_a: GO:0046928 ! regulation of neurotransmitter secretion
is_a: GO:0051589 ! negative regulation of neurotransmitter transport
is_a: GO:1903531 ! negative regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007269 ! neurotransmitter secretion
relationship: negatively_regulates GO:0007269 ! neurotransmitter secretion

[Term]
id: GO:0046942
name: carboxylic acid transport
namespace: biological_process
def: "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai]
is_a: GO:0015711 ! organic anion transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion
relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion

[Term]
id: GO:0046943
name: carboxylic acid transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai]
xref: Reactome:R-HSA-390347 "Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane"
is_a: GO:0008514 ! organic anion transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion
relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion
relationship: part_of GO:1905039 ! carboxylic acid transmembrane transport

[Term]
id: GO:0047496
name: vesicle transport along microtubule
namespace: biological_process
def: "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." [GOC:ecd, GOC:rl]
synonym: "microtubule-based vesicle localization" EXACT [GOC:rl]
is_a: GO:0072384 ! organelle transport along microtubule
is_a: GO:0099518 ! vesicle cytoskeletal trafficking
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input GO:0031982 ! vesicle
intersection_of: results_in_transport_along GO:0005874 ! microtubule

[Term]
id: GO:0048048
name: embryonic eye morphogenesis
namespace: biological_process
def: "The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized." [GOC:jid]
is_a: GO:0048562 ! embryonic organ morphogenesis
is_a: GO:0048592 ! eye morphogenesis

[Term]
id: GO:0048066
name: developmental pigmentation
namespace: biological_process
def: "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." [ISBN:0582227089]
synonym: "pigmentation during development" RELATED []
is_a: GO:0043473 ! pigmentation

[Term]
id: GO:0048070
name: regulation of developmental pigmentation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb]
synonym: "regulation of pigmentation during development" EXACT [GOC:dph, GOC:tb]
is_a: GO:0120305 ! regulation of pigmentation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048066 ! developmental pigmentation
relationship: regulates GO:0048066 ! developmental pigmentation

[Term]
id: GO:0048086
name: negative regulation of developmental pigmentation
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb]
synonym: "down regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb]
synonym: "down-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb]
synonym: "downregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb]
synonym: "inhibition of pigmentation" NARROW []
is_a: GO:0048070 ! regulation of developmental pigmentation
is_a: GO:0048519 ! negative regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048066 ! developmental pigmentation
relationship: negatively_regulates GO:0048066 ! developmental pigmentation

[Term]
id: GO:0048087
name: positive regulation of developmental pigmentation
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb]
synonym: "activation of developmental pigmentation" NARROW [GOC:dph, GOC:tb]
synonym: "stimulation of developmental pigmentation" NARROW [GOC:dph, GOC:tb]
synonym: "up regulation of developmental pigmentation" EXACT [GOC:dph]
synonym: "up-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb]
synonym: "upregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb]
is_a: GO:0048070 ! regulation of developmental pigmentation
is_a: GO:0048518 ! positive regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048066 ! developmental pigmentation
relationship: positively_regulates GO:0048066 ! developmental pigmentation

[Term]
id: GO:0048103
name: somatic stem cell division
namespace: biological_process
def: "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line." [GOC:jid, ISBN:0582227089]
synonym: "somatic stem cell renewal" EXACT []
is_a: GO:0017145 ! stem cell division
intersection_of: GO:0051301 ! cell division
intersection_of: has_primary_input CL:0000723 ! somatic stem cell
relationship: has_primary_input CL:0000723 ! somatic stem cell

[Term]
id: GO:0048132
name: female germ-line stem cell asymmetric division
namespace: biological_process
alt_id: GO:0048141
def: "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes." [GOC:jid, GOC:mtg_sensu]
synonym: "female germ-line stem cell renewal" EXACT []
is_a: GO:0098728 ! germline stem cell asymmetric division
intersection_of: GO:0008356 ! asymmetric cell division
intersection_of: has_primary_input CL:0000022 ! female germ line stem cell
relationship: has_primary_input CL:0000022 ! female germ line stem cell
relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda
relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda
relationship: part_of GO:0048477 ! oogenesis

[Term]
id: GO:0048137
name: spermatocyte division
namespace: biological_process
def: "The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids." [GOC:jid, GOC:pr, ISBN:0879694238]
synonym: "spermatocyte cell division" EXACT []
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0051301 ! cell division
intersection_of: GO:0051301 ! cell division
intersection_of: has_primary_input CL:0000017 ! spermatocyte
relationship: has_primary_input CL:0000017 ! spermatocyte
relationship: part_of GO:0007283 ! spermatogenesis

[Term]
id: GO:0048144
name: fibroblast proliferation
namespace: biological_process
def: "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population." [GOC:jid]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000057 ! fibroblast
relationship: acts_on_population_of CL:0000057 ! fibroblast

[Term]
id: GO:0048145
name: regulation of fibroblast proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048144 ! fibroblast proliferation
relationship: regulates GO:0048144 ! fibroblast proliferation

[Term]
id: GO:0048146
name: positive regulation of fibroblast proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid]
synonym: "activation of fibroblast proliferation" NARROW []
synonym: "stimulation of fibroblast proliferation" NARROW []
synonym: "up regulation of fibroblast proliferation" EXACT []
synonym: "up-regulation of fibroblast proliferation" EXACT []
synonym: "upregulation of fibroblast proliferation" EXACT []
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0048145 ! regulation of fibroblast proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048144 ! fibroblast proliferation
relationship: positively_regulates GO:0048144 ! fibroblast proliferation

[Term]
id: GO:0048147
name: negative regulation of fibroblast proliferation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid]
synonym: "down regulation of fibroblast proliferation" EXACT []
synonym: "down-regulation of fibroblast proliferation" EXACT []
synonym: "downregulation of fibroblast proliferation" EXACT []
synonym: "inhibition of fibroblast proliferation" NARROW []
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0048145 ! regulation of fibroblast proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048144 ! fibroblast proliferation
relationship: negatively_regulates GO:0048144 ! fibroblast proliferation

[Term]
id: GO:0048193
name: Golgi vesicle transport
namespace: biological_process
def: "The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles." [GOC:jid, ISBN:0716731363, PMID:10219233]
subset: goslim_yeast
synonym: "Golgi-derived vesicle transport" RELATED []
is_a: GO:0016192 ! vesicle-mediated transport
intersection_of: GO:0006810 ! transport
intersection_of: results_in_transport_to_from_or_in GO:0005798 ! Golgi-associated vesicle
relationship: results_in_transport_to_from_or_in GO:0005798 ! Golgi-associated vesicle

[Term]
id: GO:0048194
name: Golgi vesicle budding
namespace: biological_process
def: "The evagination of the Golgi membrane, resulting in formation of a vesicle." [GOC:jid, ISBN:0716731363, PMID:10219233]
synonym: "dictyosome vesicle budding" NARROW []
synonym: "Golgi-derived vesicle budding" EXACT []
is_a: GO:0006900 ! vesicle budding from membrane
intersection_of: GO:0006900 ! vesicle budding from membrane
intersection_of: has_primary_output GO:0005798 ! Golgi-associated vesicle
intersection_of: occurs_in GO:0000139 ! Golgi membrane
relationship: has_primary_output GO:0005798 ! Golgi-associated vesicle
relationship: occurs_in GO:0000139 ! Golgi membrane
relationship: part_of GO:0048193 ! Golgi vesicle transport

[Term]
id: GO:0048199
name: vesicle targeting, to, from or within Golgi
namespace: biological_process
def: "The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233]
synonym: "dictyosome vesicle targeting" NARROW []
synonym: "Golgi vesicle targeting" EXACT []
synonym: "vesicle targeting, to, from or within dictyosome" NARROW []
is_a: GO:0006903 ! vesicle targeting
intersection_of: GO:0006903 ! vesicle targeting
intersection_of: has_primary_input GO:0005798 ! Golgi-associated vesicle
intersection_of: results_in_transport_to_from_or_in GO:0005794 ! Golgi apparatus
relationship: has_primary_input GO:0005798 ! Golgi-associated vesicle
relationship: part_of GO:0048193 ! Golgi vesicle transport
relationship: results_in_transport_to_from_or_in GO:0005794 ! Golgi apparatus

[Term]
id: GO:0048209
name: regulation of vesicle targeting, to, from or within Golgi
namespace: biological_process
def: "Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233]
synonym: "regulation of Golgi vesicle targeting" EXACT []
is_a: GO:0060341 ! regulation of cellular localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048199 ! vesicle targeting, to, from or within Golgi
relationship: regulates GO:0048199 ! vesicle targeting, to, from or within Golgi

[Term]
id: GO:0048232
name: male gamete generation
namespace: biological_process
def: "Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction." [GOC:dph, GOC:jid]
is_a: GO:0007276 ! gamete generation

[Term]
id: GO:0048240
name: sperm capacitation
namespace: biological_process
def: "A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium." [GOC:jid, ISBN:978-3-642-58301-8, PMID:11820818]
comment: Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract.
synonym: "sperm activation" RELATED [PMID:23180860]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0048469 ! cell maturation
relationship: part_of GO:0007286 ! spermatid development

[Term]
id: GO:0048243
name: norepinephrine secretion
namespace: biological_process
def: "The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system." [GOC:ef, GOC:jid]
synonym: "noradrenaline secretion" EXACT []
is_a: GO:0015874 ! norepinephrine transport
is_a: GO:0023061 ! signal release
is_a: GO:0050432 ! catecholamine secretion
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+)

[Term]
id: GO:0048251
name: elastic fiber assembly
namespace: biological_process
def: "Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching." [GOC:jid, PMID:10841810, PMID:12615674]
synonym: "elastic fibre assembly" EXACT []
synonym: "elastin fiber assembly" EXACT [GOC:BHF]
synonym: "elastin fibre assembly" EXACT [GOC:BHF]
is_a: GO:0085029 ! extracellular matrix assembly
is_a: GO:0097435 ! supramolecular fiber organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0071953 ! elastic fiber
relationship: results_in_assembly_of GO:0071953 ! elastic fiber

[Term]
id: GO:0048280
name: vesicle fusion with Golgi apparatus
namespace: biological_process
def: "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi." [GOC:jid]
is_a: GO:0006906 ! vesicle fusion
is_a: GO:0007030 ! Golgi organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_fusion_of GO:0005794 ! Golgi apparatus
intersection_of: results_in_fusion_of GO:0031982 ! vesicle
relationship: part_of GO:0048193 ! Golgi vesicle transport
relationship: results_in_fusion_of GO:0005794 ! Golgi apparatus
relationship: results_in_fusion_of GO:0031982 ! vesicle

[Term]
id: GO:0048284
name: organelle fusion
namespace: biological_process
def: "The creation of a single organelle from two or more organelles." [GOC:jid]
subset: goslim_pir
subset: goslim_yeast
is_a: GO:0006996 ! organelle organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_fusion_of GO:0043226 ! organelle
relationship: results_in_fusion_of GO:0043226 ! organelle

[Term]
id: GO:0048285
name: organelle fission
namespace: biological_process
def: "The creation of two or more organelles by division of one organelle." [GOC:jid]
subset: goslim_pir
subset: goslim_yeast
is_a: GO:0006996 ! organelle organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_fission_of GO:0043226 ! organelle
relationship: results_in_fission_of GO:0043226 ! organelle

[Term]
id: GO:0048288
name: nuclear membrane fusion involved in karyogamy
namespace: biological_process
def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei." [GOC:jid]
synonym: "nuclear membrane fusion during karyogamy" RELATED [GOC:dph, GOC:tb]
is_a: GO:0000740 ! nuclear membrane fusion
intersection_of: GO:0000740 ! nuclear membrane fusion
intersection_of: part_of GO:0000741 ! karyogamy
relationship: part_of GO:0000741 ! karyogamy

[Term]
id: GO:0048308
name: organelle inheritance
namespace: biological_process
def: "The partitioning of organelles between daughter cells at cell division." [GOC:jid]
subset: goslim_pir
subset: goslim_yeast
is_a: GO:0006996 ! organelle organization

[Term]
id: GO:0048313
name: Golgi inheritance
namespace: biological_process
def: "The partitioning of Golgi apparatus between daughter cells at cell division." [GOC:jid, PMID:12851069]
synonym: "Golgi apparatus inheritance" EXACT []
synonym: "Golgi division" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb]
synonym: "Golgi partitioning" EXACT []
is_a: GO:0007030 ! Golgi organization
is_a: GO:0048308 ! organelle inheritance
intersection_of: GO:0048308 ! organelle inheritance
intersection_of: results_in_distribution_of GO:0005794 ! Golgi apparatus
relationship: results_in_distribution_of GO:0005794 ! Golgi apparatus

[Term]
id: GO:0048318
name: axial mesoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." [GOC:dgh]
is_a: GO:0007498 ! mesoderm development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003068 ! axial mesoderm
relationship: results_in_development_of UBERON:0003068 ! axial mesoderm

[Term]
id: GO:0048319
name: axial mesoderm morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the axial mesoderm are generated and organized." [GOC:go_curators]
is_a: GO:0048332 ! mesoderm morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003068 ! axial mesoderm
relationship: part_of GO:0048318 ! axial mesoderm development
relationship: results_in_morphogenesis_of UBERON:0003068 ! axial mesoderm

[Term]
id: GO:0048320
name: axial mesoderm formation
namespace: biological_process
def: "The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh]
is_a: GO:0001707 ! mesoderm formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003068 ! axial mesoderm
relationship: part_of GO:0048319 ! axial mesoderm morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0003068 ! axial mesoderm

[Term]
id: GO:0048332
name: mesoderm morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the mesoderm are generated and organized." [GOC:go_curators]
is_a: GO:0048729 ! tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000926 ! mesoderm
relationship: part_of GO:0007498 ! mesoderm development
relationship: results_in_morphogenesis_of UBERON:0000926 ! mesoderm

[Term]
id: GO:0048333
name: mesodermal cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell." [GOC:dgh]
synonym: "mesoderm cell differentiation" EXACT []
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000222 ! mesodermal cell
relationship: part_of GO:0001707 ! mesoderm formation
relationship: results_in_acquisition_of_features_of CL:0000222 ! mesodermal cell

[Term]
id: GO:0048339
name: paraxial mesoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube." [GOC:dgh]
is_a: GO:0007498 ! mesoderm development
is_a: GO:0060485 ! mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003077 ! paraxial mesoderm
relationship: results_in_development_of UBERON:0003077 ! paraxial mesoderm

[Term]
id: GO:0048340
name: paraxial mesoderm morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the paraxial mesoderm are generated and organized." [GOC:go_curators]
is_a: GO:0048332 ! mesoderm morphogenesis
is_a: GO:0072132 ! mesenchyme morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003077 ! paraxial mesoderm
relationship: part_of GO:0048339 ! paraxial mesoderm development
relationship: results_in_morphogenesis_of UBERON:0003077 ! paraxial mesoderm

[Term]
id: GO:0048341
name: paraxial mesoderm formation
namespace: biological_process
def: "The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh]
is_a: GO:0001707 ! mesoderm formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003077 ! paraxial mesoderm
relationship: part_of GO:0048340 ! paraxial mesoderm morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0003077 ! paraxial mesoderm

[Term]
id: GO:0048368
name: lateral mesoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure." [GOC:go_curators]
synonym: "lateral plate mesoderm development" EXACT []
is_a: GO:0007498 ! mesoderm development
is_a: GO:0060485 ! mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003081 ! lateral plate mesoderm
relationship: results_in_development_of UBERON:0003081 ! lateral plate mesoderm

[Term]
id: GO:0048369
name: lateral mesoderm morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the lateral mesoderm are generated and organized." [GOC:go_curators]
synonym: "lateral plate mesoderm morphogenesis" EXACT []
is_a: GO:0048332 ! mesoderm morphogenesis
is_a: GO:0072132 ! mesenchyme morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm
relationship: part_of GO:0048368 ! lateral mesoderm development
relationship: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm

[Term]
id: GO:0048370
name: lateral mesoderm formation
namespace: biological_process
def: "The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:jid]
synonym: "lateral plate mesoderm biosynthesis" EXACT []
synonym: "lateral plate mesoderm formation" EXACT []
is_a: GO:0001707 ! mesoderm formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm
relationship: part_of GO:0048369 ! lateral mesoderm morphogenesis
relationship: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm

[Term]
id: GO:0048389
name: intermediate mesoderm development
namespace: biological_process
def: "The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." [GOC:dgh]
is_a: GO:0007498 ! mesoderm development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003064 ! intermediate mesoderm
relationship: results_in_development_of UBERON:0003064 ! intermediate mesoderm

[Term]
id: GO:0048390
name: intermediate mesoderm morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the intermediate mesoderm are generated and organized." [GOC:go_curators]
is_a: GO:0048332 ! mesoderm morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003064 ! intermediate mesoderm
relationship: part_of GO:0048389 ! intermediate mesoderm development
relationship: results_in_morphogenesis_of UBERON:0003064 ! intermediate mesoderm

[Term]
id: GO:0048391
name: intermediate mesoderm formation
namespace: biological_process
def: "The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh]
is_a: GO:0001707 ! mesoderm formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003064 ! intermediate mesoderm
relationship: part_of GO:0048390 ! intermediate mesoderm morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0003064 ! intermediate mesoderm

[Term]
id: GO:0048468
name: cell development
namespace: biological_process
def: "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." [GOC:go_curators]
subset: goslim_candida
synonym: "terminal differentiation" RELATED [GOC:dph, GOC:tb]
is_a: GO:0048856 ! anatomical structure development
is_a: GO:0048869 ! cellular developmental process
intersection_of: GO:0008150 ! biological process
intersection_of: results_in_development_of CL:0000000 ! cell
relationship: part_of GO:0030154 ! cell differentiation
relationship: results_in_development_of CL:0000000 ! cell
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI

[Term]
id: GO:0048469
name: cell maturation
namespace: biological_process
def: "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." [GOC:go_curators]
subset: goslim_pir
synonym: "functional differentiation" RELATED [GOC:dph]
is_a: GO:0048869 ! cellular developmental process
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000000 ! cell
relationship: part_of GO:0048468 ! cell development
relationship: results_in_maturation_of CL:0000000 ! cell
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI

[Term]
id: GO:0048477
name: oogenesis
namespace: biological_process
alt_id: GO:0009993
alt_id: GO:0048157
def: "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr]
synonym: "ovum development" EXACT systematic_synonym []
xref: Wikipedia:Oogenesis
is_a: GO:0007281 ! germ cell development
is_a: GO:0007292 ! female gamete generation
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:0000025 ! egg cell
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: results_in_development_of CL:0000025 ! egg cell

[Term]
id: GO:0048483
name: autonomic nervous system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands." [FMA:9905, GOC:jid, GOC:sr]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002410 ! autonomic nervous system
relationship: part_of GO:0007399 ! nervous system development
relationship: results_in_development_of UBERON:0002410 ! autonomic nervous system

[Term]
id: GO:0048485
name: sympathetic nervous system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter." [FMA:9906, GOC:jid, GOC:sr]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000013 ! sympathetic nervous system
relationship: part_of GO:0048483 ! autonomic nervous system development
relationship: results_in_development_of UBERON:0000013 ! sympathetic nervous system

[Term]
id: GO:0048505
name: regulation of timing of cell differentiation
namespace: biological_process
def: "The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development." [GOC:bf, GOC:dph, GOC:jid, GOC:tb]
synonym: "timing of cell differentiation" RELATED []
is_a: GO:0040034 ! regulation of development, heterochronic
is_a: GO:0045595 ! regulation of cell differentiation

[Term]
id: GO:0048511
name: rhythmic process
namespace: biological_process
def: "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism." [GOC:jid]
subset: goslim_pir
synonym: "rhythm" RELATED []
is_a: GO:0008150 ! biological process
relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms
relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms

[Term]
id: GO:0048513
name: animal organ development
namespace: biological_process
def: "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dph, GOC:jid]
synonym: "development of an organ" EXACT []
synonym: "organogenesis" EXACT []
xref: Wikipedia:Organogenesis
is_a: GO:0048856 ! anatomical structure development
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25943" xsd:anyURI

[Term]
id: GO:0048514
name: blood vessel morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:jid]
is_a: GO:0035239 ! tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001981 ! blood vessel
relationship: part_of GO:0001568 ! blood vessel development
relationship: results_in_morphogenesis_of UBERON:0001981 ! blood vessel

[Term]
id: GO:0048515
name: spermatid differentiation
namespace: biological_process
def: "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:jid]
synonym: "spermatid cell differentiation" EXACT []
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000018 ! spermatid
relationship: part_of GO:0007283 ! spermatogenesis
relationship: results_in_acquisition_of_features_of CL:0000018 ! spermatid

[Term]
id: GO:0048518
name: positive regulation of biological process
namespace: biological_process
alt_id: GO:0043119
def: "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid]
subset: gocheck_do_not_annotate
synonym: "activation of biological process" NARROW []
synonym: "positive regulation of physiological process" EXACT []
synonym: "stimulation of biological process" NARROW []
synonym: "up regulation of biological process" EXACT []
synonym: "up-regulation of biological process" EXACT []
synonym: "upregulation of biological process" EXACT []
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008150 ! biological process
relationship: positively_regulates GO:0008150 ! biological process

[Term]
id: GO:0048519
name: negative regulation of biological process
namespace: biological_process
alt_id: GO:0043118
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid]
subset: gocheck_do_not_annotate
synonym: "down regulation of biological process" EXACT []
synonym: "down-regulation of biological process" EXACT []
synonym: "downregulation of biological process" EXACT []
synonym: "inhibition of biological process" NARROW []
synonym: "negative regulation of physiological process" EXACT []
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008150 ! biological process
relationship: negatively_regulates GO:0008150 ! biological process

[Term]
id: GO:0048520
name: positive regulation of behavior
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr]
synonym: "activation of behavior" NARROW []
synonym: "stimulation of behavior" NARROW []
synonym: "up regulation of behavior" EXACT []
synonym: "up-regulation of behavior" EXACT []
synonym: "upregulation of behavior" EXACT []
is_a: GO:0050795 ! regulation of behavior
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007610 ! behavior
relationship: positively_regulates GO:0007610 ! behavior

[Term]
id: GO:0048521
name: negative regulation of behavior
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr]
synonym: "down regulation of behavior" EXACT []
synonym: "down-regulation of behavior" EXACT []
synonym: "downregulation of behavior" EXACT []
synonym: "inhibition of behavior" NARROW []
is_a: GO:0050795 ! regulation of behavior
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007610 ! behavior
relationship: negatively_regulates GO:0007610 ! behavior

[Term]
id: GO:0048522
name: positive regulation of cellular process
namespace: biological_process
alt_id: GO:0051242
def: "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid]
subset: gocheck_do_not_annotate
synonym: "activation of cellular process" NARROW []
synonym: "positive regulation of cellular physiological process" EXACT []
synonym: "stimulation of cellular process" NARROW []
synonym: "up regulation of cellular process" EXACT []
synonym: "up-regulation of cellular process" EXACT []
synonym: "upregulation of cellular process" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009987 ! cellular process
relationship: positively_regulates GO:0009987 ! cellular process

[Term]
id: GO:0048523
name: negative regulation of cellular process
namespace: biological_process
alt_id: GO:0051243
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid]
subset: gocheck_do_not_annotate
synonym: "down regulation of cellular process" EXACT []
synonym: "down-regulation of cellular process" EXACT []
synonym: "downregulation of cellular process" EXACT []
synonym: "inhibition of cellular process" NARROW []
synonym: "negative regulation of cellular physiological process" EXACT []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009987 ! cellular process
relationship: negatively_regulates GO:0009987 ! cellular process

[Term]
id: GO:0048534
name: hematopoietic or lymphoid organ development
namespace: biological_process
def: "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." [GOC:add, GOC:rl, ISBN:0781735149]
synonym: "haematopoietic or lymphoid organ development" EXACT []
synonym: "haemopoietic or lymphoid organ development" EXACT []
synonym: "hemopoietic or lymphoid organ development" EXACT []
is_a: GO:0048513 ! animal organ development
relationship: part_of GO:0002520 ! immune system development

[Term]
id: GO:0048536
name: spleen development
namespace: biological_process
def: "The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions." [GOC:add, ISBN:0781735149]
is_a: GO:0048534 ! hematopoietic or lymphoid organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002106 ! spleen
relationship: results_in_development_of UBERON:0002106 ! spleen

[Term]
id: GO:0048539
name: bone marrow development
namespace: biological_process
def: "The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure." [GOC:add, ISBN:0781735149]
is_a: GO:0009888 ! tissue development
is_a: GO:0048534 ! hematopoietic or lymphoid organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002371 ! bone marrow
relationship: part_of GO:0060348 ! bone development
relationship: results_in_development_of UBERON:0002371 ! bone marrow

[Term]
id: GO:0048545
name: response to steroid hormone
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." [GOC:go_curators]
synonym: "response to steroid hormone stimulus" EXACT [GOC:dos]
is_a: GO:0009725 ! response to hormone
is_a: GO:0014070 ! response to organic cyclic compound
is_a: GO:0033993 ! response to lipid
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:26764 ! steroid hormone
relationship: has_primary_input CHEBI:26764 ! steroid hormone

[Term]
id: GO:0048546
name: digestive tract morphogenesis
namespace: biological_process
alt_id: GO:0048547
def: "The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:dph, GOC:go_curators, PMID:12618131]
synonym: "alimentary canal morphogenesis" EXACT []
synonym: "digestive tube morphogenesis" EXACT []
synonym: "gastrointestinal tract morphogenesis" EXACT []
synonym: "gut morphogenesis" BROAD [GOC:dph]
synonym: "intestinal morphogenesis" NARROW []
is_a: GO:0035239 ! tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001555 ! digestive tract
relationship: part_of GO:0048565 ! digestive tract development
relationship: results_in_morphogenesis_of UBERON:0001555 ! digestive tract

[Term]
id: GO:0048562
name: embryonic organ morphogenesis
namespace: biological_process
def: "Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid]
is_a: GO:0009887 ! animal organ morphogenesis
is_a: GO:0048598 ! embryonic morphogenesis
relationship: part_of GO:0048568 ! embryonic organ development

[Term]
id: GO:0048565
name: digestive tract development
namespace: biological_process
def: "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:go_curators]
synonym: "gut development" BROAD [GOC:dph]
synonym: "intestinal development" NARROW []
synonym: "intestine development" NARROW []
is_a: GO:0035295 ! tube development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001555 ! digestive tract
relationship: part_of GO:0055123 ! digestive system development
relationship: results_in_development_of UBERON:0001555 ! digestive tract

[Term]
id: GO:0048568
name: embryonic organ development
namespace: biological_process
def: "Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid]
synonym: "embryonic organogenesis" EXACT []
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: part_of GO:0009790 ! embryo development
intersection_of: results_in_development_of UBERON:0000062 ! organ
relationship: part_of GO:0009790 ! embryo development
relationship: results_in_development_of UBERON:0000062 ! organ

[Term]
id: GO:0048570
name: notochord morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:jid]
is_a: GO:0048562 ! embryonic organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002328 ! notochord
relationship: part_of GO:0030903 ! notochord development
relationship: results_in_morphogenesis_of UBERON:0002328 ! notochord

[Term]
id: GO:0048580
name: regulation of post-embryonic development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid]
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009791 ! post-embryonic development
relationship: regulates GO:0009791 ! post-embryonic development

[Term]
id: GO:0048581
name: negative regulation of post-embryonic development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid]
synonym: "down regulation of post-embryonic development" EXACT []
synonym: "down-regulation of post-embryonic development" EXACT []
synonym: "downregulation of post-embryonic development" EXACT []
synonym: "inhibition of post-embryonic development" NARROW []
is_a: GO:0048580 ! regulation of post-embryonic development
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009791 ! post-embryonic development
relationship: negatively_regulates GO:0009791 ! post-embryonic development

[Term]
id: GO:0048582
name: positive regulation of post-embryonic development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid]
synonym: "activation of post-embryonic development" NARROW []
synonym: "stimulation of post-embryonic development" NARROW []
synonym: "up regulation of post-embryonic development" EXACT []
synonym: "up-regulation of post-embryonic development" EXACT []
synonym: "upregulation of post-embryonic development" EXACT []
is_a: GO:0048580 ! regulation of post-embryonic development
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009791 ! post-embryonic development
relationship: positively_regulates GO:0009791 ! post-embryonic development

[Term]
id: GO:0048583
name: regulation of response to stimulus
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0050896 ! response to stimulus
relationship: regulates GO:0050896 ! response to stimulus

[Term]
id: GO:0048584
name: positive regulation of response to stimulus
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "activation of response to stimulus" NARROW []
synonym: "stimulation of response to stimulus" NARROW []
synonym: "up regulation of response to stimulus" EXACT []
synonym: "up-regulation of response to stimulus" EXACT []
synonym: "upregulation of response to stimulus" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0050896 ! response to stimulus
relationship: positively_regulates GO:0050896 ! response to stimulus

[Term]
id: GO:0048585
name: negative regulation of response to stimulus
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
synonym: "down regulation of response to stimulus" EXACT []
synonym: "down-regulation of response to stimulus" EXACT []
synonym: "downregulation of response to stimulus" EXACT []
synonym: "inhibition of response to stimulus" NARROW []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0050896 ! response to stimulus
relationship: negatively_regulates GO:0050896 ! response to stimulus

[Term]
id: GO:0048588
name: developmental cell growth
namespace: biological_process
def: "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." [GOC:go_curators, GOC:isa_complete]
subset: gocheck_do_not_annotate
synonym: "developmental growth of a unicellular organism" EXACT []
is_a: GO:0016049 ! cell growth
is_a: GO:0048589 ! developmental growth
relationship: part_of GO:0048468 ! cell development
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI

[Term]
id: GO:0048589
name: developmental growth
namespace: biological_process
def: "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:go_curators]
is_a: GO:0040007 ! growth
intersection_of: GO:0040007 ! growth
intersection_of: part_of GO:0032502 ! developmental process
relationship: part_of GO:0032502 ! developmental process

[Term]
id: GO:0048592
name: eye morphogenesis
namespace: biological_process
alt_id: GO:0048748
def: "The process in which the anatomical structures of the eye are generated and organized." [GOC:jid, GOC:mtg_sensu]
is_a: GO:0090596 ! sensory organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000970 ! eye
relationship: part_of GO:0001654 ! eye development
relationship: results_in_morphogenesis_of UBERON:0000970 ! eye

[Term]
id: GO:0048593
name: camera-type eye morphogenesis
namespace: biological_process
alt_id: GO:0048594
alt_id: GO:0048595
def: "The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:jid, GOC:mtg_sensu]
synonym: "camera-style eye morphogenesis" EXACT [GOC:dph]
is_a: GO:0048592 ! eye morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000019 ! camera-type eye
relationship: part_of GO:0043010 ! camera-type eye development
relationship: results_in_morphogenesis_of UBERON:0000019 ! camera-type eye

[Term]
id: GO:0048596
name: embryonic camera-type eye morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the eye are generated and organized during embryonic development." [GOC:jid, GOC:mtg_sensu]
synonym: "embryonic eye morphogenesis" BROAD []
is_a: GO:0048048 ! embryonic eye morphogenesis
relationship: part_of GO:0031076 ! embryonic camera-type eye development
relationship: part_of GO:0048593 ! camera-type eye morphogenesis

[Term]
id: GO:0048598
name: embryonic morphogenesis
namespace: biological_process
alt_id: GO:0048828
def: "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." [GOC:jid, GOC:mtg_sensu]
synonym: "embryonic anatomical structure morphogenesis" EXACT [GOC:dph, GOC:tb]
is_a: GO:0009653 ! anatomical structure morphogenesis
relationship: part_of GO:0009790 ! embryo development

[Term]
id: GO:0048599
name: oocyte development
namespace: biological_process
def: "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:go_curators]
is_a: GO:0007281 ! germ cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000023 ! oocyte
relationship: part_of GO:0009994 ! oocyte differentiation
relationship: results_in_development_of CL:0000023 ! oocyte

[Term]
id: GO:0048601
name: oocyte morphogenesis
namespace: biological_process
def: "The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte." [GOC:go_curators]
synonym: "oocyte morphogenesis during differentiation" EXACT []
is_a: GO:0000902 ! cell morphogenesis
is_a: GO:0003006 ! developmental process involved in reproduction
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of CL:0000023 ! oocyte
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of GO:0048599 ! oocyte development
relationship: results_in_morphogenesis_of CL:0000023 ! oocyte

[Term]
id: GO:0048608
name: reproductive structure development
namespace: biological_process
def: "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." [GOC:dph, GOC:isa_complete, GOC:jid]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0048856 ! anatomical structure development
relationship: part_of GO:0061458 ! reproductive system development
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23445" xsd:anyURI

[Term]
id: GO:0048609
name: multicellular organismal reproductive process
namespace: biological_process
def: "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." [GOC:dph, GOC:jid, GOC:tb]
synonym: "organismal reproductive process" BROAD []
synonym: "reproductive process in a multicellular organism" EXACT []
is_a: GO:0022414 ! reproductive process
relationship: part_of GO:0032504 ! multicellular organism reproduction

[Term]
id: GO:0048627
name: myoblast development
namespace: biological_process
def: "The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle]
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000056 ! myoblast
relationship: part_of GO:0045445 ! myoblast differentiation
relationship: results_in_development_of CL:0000056 ! myoblast

[Term]
id: GO:0048628
name: myoblast maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle]
is_a: GO:0048469 ! cell maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000056 ! myoblast
relationship: part_of GO:0048627 ! myoblast development
relationship: results_in_maturation_of CL:0000056 ! myoblast

[Term]
id: GO:0048630
name: skeletal muscle tissue growth
namespace: biological_process
def: "The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size." [GOC:lm, PMID:15726494, PMID:15907921]
is_a: GO:0048589 ! developmental growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: results_in_growth_of UBERON:0001134 ! skeletal muscle tissue
relationship: part_of GO:0007519 ! skeletal muscle tissue development
relationship: results_in_growth_of UBERON:0001134 ! skeletal muscle tissue

[Term]
id: GO:0048631
name: regulation of skeletal muscle tissue growth
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921]
is_a: GO:0048638 ! regulation of developmental growth
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048630 ! skeletal muscle tissue growth
relationship: regulates GO:0048630 ! skeletal muscle tissue growth

[Term]
id: GO:0048632
name: negative regulation of skeletal muscle tissue growth
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921]
synonym: "down regulation of skeletal muscle growth" EXACT []
synonym: "down-regulation of skeletal muscle growth" EXACT []
synonym: "downregulation of skeletal muscle growth" EXACT []
synonym: "inhibition of skeletal muscle growth" NARROW []
is_a: GO:0048631 ! regulation of skeletal muscle tissue growth
is_a: GO:0048640 ! negative regulation of developmental growth
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048630 ! skeletal muscle tissue growth
relationship: negatively_regulates GO:0048630 ! skeletal muscle tissue growth

[Term]
id: GO:0048633
name: positive regulation of skeletal muscle tissue growth
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921]
synonym: "activation of skeletal muscle growth" NARROW []
synonym: "stimulation of skeletal muscle growth" NARROW []
synonym: "up regulation of skeletal muscle growth" EXACT []
synonym: "up-regulation of skeletal muscle growth" EXACT []
synonym: "upregulation of skeletal muscle growth" EXACT []
is_a: GO:0048631 ! regulation of skeletal muscle tissue growth
is_a: GO:0048639 ! positive regulation of developmental growth
is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048630 ! skeletal muscle tissue growth
relationship: positively_regulates GO:0048630 ! skeletal muscle tissue growth

[Term]
id: GO:0048634
name: regulation of muscle organ development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of muscle development." [GOC:go_curators]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007517 ! muscle organ development
relationship: regulates GO:0007517 ! muscle organ development

[Term]
id: GO:0048635
name: negative regulation of muscle organ development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development." [GOC:go_curators]
synonym: "down regulation of muscle development" EXACT []
synonym: "down-regulation of muscle development" EXACT []
synonym: "downregulation of muscle development" EXACT []
synonym: "inhibition of muscle development" NARROW []
is_a: GO:0048634 ! regulation of muscle organ development
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007517 ! muscle organ development
relationship: negatively_regulates GO:0007517 ! muscle organ development

[Term]
id: GO:0048636
name: positive regulation of muscle organ development
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of muscle development." [GOC:go_curators]
synonym: "activation of muscle development" NARROW []
synonym: "stimulation of muscle development" NARROW []
synonym: "up regulation of muscle development" EXACT []
synonym: "up-regulation of muscle development" EXACT []
synonym: "upregulation of muscle development" EXACT []
is_a: GO:0048634 ! regulation of muscle organ development
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007517 ! muscle organ development
relationship: positively_regulates GO:0007517 ! muscle organ development

[Term]
id: GO:0048638
name: regulation of developmental growth
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of developmental growth." [GOC:go_curators]
is_a: GO:0040008 ! regulation of growth
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048589 ! developmental growth
relationship: regulates GO:0048589 ! developmental growth

[Term]
id: GO:0048639
name: positive regulation of developmental growth
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of developmental growth." [GOC:go_curators]
synonym: "activation of developmental growth" NARROW []
synonym: "stimulation of developmental growth" NARROW []
synonym: "up regulation of developmental growth" EXACT []
synonym: "up-regulation of developmental growth" EXACT []
synonym: "upregulation of developmental growth" EXACT []
is_a: GO:0045927 ! positive regulation of growth
is_a: GO:0048638 ! regulation of developmental growth
is_a: GO:0051094 ! positive regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048589 ! developmental growth
relationship: positively_regulates GO:0048589 ! developmental growth

[Term]
id: GO:0048640
name: negative regulation of developmental growth
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." [GOC:go_curators]
synonym: "down regulation of developmental growth" EXACT []
synonym: "down-regulation of developmental growth" EXACT []
synonym: "downregulation of developmental growth" EXACT []
synonym: "inhibition of developmental growth" NARROW []
is_a: GO:0045926 ! negative regulation of growth
is_a: GO:0048638 ! regulation of developmental growth
is_a: GO:0051093 ! negative regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048589 ! developmental growth
relationship: negatively_regulates GO:0048589 ! developmental growth

[Term]
id: GO:0048641
name: regulation of skeletal muscle tissue development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators]
is_a: GO:0016202 ! regulation of striated muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007519 ! skeletal muscle tissue development
relationship: regulates GO:0007519 ! skeletal muscle tissue development

[Term]
id: GO:0048642
name: negative regulation of skeletal muscle tissue development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators]
synonym: "down regulation of skeletal muscle development" EXACT []
synonym: "down-regulation of skeletal muscle development" EXACT []
synonym: "downregulation of skeletal muscle development" EXACT []
synonym: "inhibition of skeletal muscle development" NARROW []
is_a: GO:0045843 ! negative regulation of striated muscle tissue development
is_a: GO:0048641 ! regulation of skeletal muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007519 ! skeletal muscle tissue development
relationship: negatively_regulates GO:0007519 ! skeletal muscle tissue development

[Term]
id: GO:0048643
name: positive regulation of skeletal muscle tissue development
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of skeletal muscle tissue development." [GOC:go_curators]
synonym: "activation of skeletal muscle development" NARROW []
synonym: "stimulation of skeletal muscle development" NARROW []
synonym: "up regulation of skeletal muscle development" EXACT []
synonym: "up-regulation of skeletal muscle development" EXACT []
synonym: "upregulation of skeletal muscle development" EXACT []
is_a: GO:0045844 ! positive regulation of striated muscle tissue development
is_a: GO:0048641 ! regulation of skeletal muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007519 ! skeletal muscle tissue development
relationship: positively_regulates GO:0007519 ! skeletal muscle tissue development

[Term]
id: GO:0048644
name: muscle organ morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of muscle are generated and organized." [GOC:jid]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001630 ! muscle organ
relationship: part_of GO:0007517 ! muscle organ development
relationship: results_in_morphogenesis_of UBERON:0001630 ! muscle organ

[Term]
id: GO:0048645
name: animal organ formation
namespace: biological_process
def: "The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ." [GOC:dph, GOC:jid]
synonym: "animal organ primordium initiation" NARROW []
synonym: "initiation of an animal organ primordium" NARROW []
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003103 ! compound organ
relationship: part_of GO:0009887 ! animal organ morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0003103 ! compound organ

[Term]
id: GO:0048646
name: anatomical structure formation involved in morphogenesis
namespace: biological_process
def: "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:dph, GOC:jid, GOC:tb]
comment: Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense.
subset: goslim_chembl
synonym: "formation of an anatomical structure involved in morphogenesis" EXACT [GOC:dph, GOC:tb]
is_a: GO:0032502 ! developmental process
relationship: part_of GO:0009653 ! anatomical structure morphogenesis

[Term]
id: GO:0048659
name: smooth muscle cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population." [CL:0000192, GOC:ebc, PMID:1840698]
synonym: "SMC proliferation" EXACT []
is_a: GO:0033002 ! muscle cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000192 ! smooth muscle cell
relationship: acts_on_population_of CL:0000192 ! smooth muscle cell

[Term]
id: GO:0048660
name: regulation of smooth muscle cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc]
synonym: "regulation of SMC proliferation" EXACT []
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048659 ! smooth muscle cell proliferation
relationship: regulates GO:0048659 ! smooth muscle cell proliferation

[Term]
id: GO:0048661
name: positive regulation of smooth muscle cell proliferation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc]
synonym: "activation of smooth muscle cell proliferation" NARROW []
synonym: "positive regulation of SMC proliferation" EXACT []
synonym: "stimulation of smooth muscle cell proliferation" NARROW []
synonym: "up regulation of smooth muscle cell proliferation" EXACT []
synonym: "up-regulation of smooth muscle cell proliferation" EXACT []
synonym: "upregulation of smooth muscle cell proliferation" EXACT []
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0048660 ! regulation of smooth muscle cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048659 ! smooth muscle cell proliferation
relationship: positively_regulates GO:0048659 ! smooth muscle cell proliferation

[Term]
id: GO:0048662
name: negative regulation of smooth muscle cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc]
synonym: "down regulation of smooth muscle cell proliferation" EXACT []
synonym: "down-regulation of smooth muscle cell proliferation" EXACT []
synonym: "downregulation of smooth muscle cell proliferation" EXACT []
synonym: "inhibition of smooth muscle cell proliferation" NARROW []
synonym: "negative regulation of SMC proliferation" EXACT []
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0048660 ! regulation of smooth muscle cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048659 ! smooth muscle cell proliferation
relationship: negatively_regulates GO:0048659 ! smooth muscle cell proliferation

[Term]
id: GO:0048666
name: neuron development
namespace: biological_process
def: "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph]
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000540 ! neuron
relationship: part_of GO:0030182 ! neuron differentiation
relationship: results_in_development_of CL:0000540 ! neuron

[Term]
id: GO:0048667
name: cell morphogenesis involved in neuron differentiation
namespace: biological_process
def: "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron." [GOC:dph, GOC:tb]
synonym: "neuron morphogenesis involved in differentiation" EXACT [GOC:dph, GOC:tb]
is_a: GO:0000902 ! cell morphogenesis
intersection_of: GO:0000902 ! cell morphogenesis
intersection_of: part_of GO:0030182 ! neuron differentiation
relationship: part_of GO:0048666 ! neuron development

[Term]
id: GO:0048699
name: generation of neurons
namespace: biological_process
def: "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." [GOC:nln]
synonym: "neuron generation" EXACT []
is_a: GO:0022008 ! neurogenesis

[Term]
id: GO:0048705
name: skeletal system morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the skeleton are generated and organized." [GOC:dph, GOC:dsf, GOC:jid, GOC:tb]
synonym: "skeletal morphogenesis" EXACT [GOC:dph, GOC:tb]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001434 ! skeletal system
relationship: part_of GO:0001501 ! skeletal system development
relationship: results_in_morphogenesis_of UBERON:0001434 ! skeletal system

[Term]
id: GO:0048729
name: tissue morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a tissue are generated and organized." [GOC:dph, GOC:jid]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000479 ! tissue
relationship: part_of GO:0009888 ! tissue development
relationship: results_in_morphogenesis_of UBERON:0000479 ! tissue

[Term]
id: GO:0048730
name: epidermis morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:jid, UBERON:0001003]
synonym: "hypodermis morphogenesis" RELATED [GOC:kmv, GOC:rk]
is_a: GO:0002009 ! morphogenesis of an epithelium
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0007376 ! outer epithelium
relationship: part_of GO:0008544 ! epidermis development
relationship: results_in_morphogenesis_of UBERON:0007376 ! outer epithelium

[Term]
id: GO:0048731
name: system development
namespace: biological_process
def: "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:dph, GOC:jid]
subset: goslim_mouse
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000467 ! anatomical system
relationship: part_of GO:0007275 ! multicellular organism development
relationship: results_in_development_of UBERON:0000467 ! anatomical system

[Term]
id: GO:0048732
name: gland development
namespace: biological_process
def: "The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion." [GOC:jid]
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002530 ! gland
relationship: results_in_development_of UBERON:0002530 ! gland

[Term]
id: GO:0048736
name: appendage development
namespace: biological_process
def: "The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [GOC:jid, GOC:rc]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000026 ! appendage
relationship: part_of GO:0007275 ! multicellular organism development
relationship: results_in_development_of UBERON:0000026 ! appendage

[Term]
id: GO:0048738
name: cardiac muscle tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm]
synonym: "heart muscle development" EXACT []
is_a: GO:0014706 ! striated muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001133 ! cardiac muscle tissue
relationship: part_of GO:0007507 ! heart development
relationship: results_in_development_of UBERON:0001133 ! cardiac muscle tissue

[Term]
id: GO:0048741
name: skeletal muscle fiber development
namespace: biological_process
def: "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:ef, GOC:jid, GOC:lm, GOC:mtg_muscle]
synonym: "skeletal muscle fibre development" EXACT []
synonym: "skeletal myofiber development" EXACT []
synonym: "skeletal myofibre development" EXACT []
is_a: GO:0014904 ! myotube cell development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of CL:0008002 ! skeletal muscle fiber
relationship: part_of GO:0007519 ! skeletal muscle tissue development
relationship: results_in_development_of CL:0008002 ! skeletal muscle fiber

[Term]
id: GO:0048742
name: regulation of skeletal muscle fiber development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:mtg_muscle, GOC:sm]
synonym: "regulation of skeletal muscle fibre development" EXACT []
synonym: "regulation of skeletal myofiber development" EXACT []
synonym: "regulation of skeletal myofibre development" EXACT []
is_a: GO:0010830 ! regulation of myotube differentiation
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048741 ! skeletal muscle fiber development
relationship: regulates GO:0048741 ! skeletal muscle fiber development

[Term]
id: GO:0048743
name: positive regulation of skeletal muscle fiber development
namespace: biological_process
def: "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle]
synonym: "activation of skeletal muscle fiber development" NARROW []
synonym: "positive regulation of skeletal muscle fibre development" EXACT []
synonym: "positive regulation of skeletal myofiber development" EXACT []
synonym: "positive regulation of skeletal myofibre development" EXACT []
synonym: "stimulation of skeletal muscle fiber development" NARROW []
synonym: "up regulation of skeletal muscle fiber development" EXACT []
synonym: "up-regulation of skeletal muscle fiber development" EXACT []
synonym: "upregulation of skeletal muscle fiber development" EXACT []
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development
is_a: GO:0048742 ! regulation of skeletal muscle fiber development
is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048741 ! skeletal muscle fiber development
relationship: positively_regulates GO:0048741 ! skeletal muscle fiber development

[Term]
id: GO:0048744
name: negative regulation of skeletal muscle fiber development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle]
synonym: "down regulation of skeletal muscle fiber development" EXACT []
synonym: "down-regulation of skeletal muscle fiber development" EXACT []
synonym: "downregulation of skeletal muscle fiber development" EXACT []
synonym: "inhibition of skeletal muscle fiber development" NARROW []
synonym: "negative regulation of skeletal muscle fibre development" EXACT []
synonym: "negative regulation of skeletal myofiber development" EXACT []
synonym: "negative regulation of skeletal myofibre development" EXACT []
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0048742 ! regulation of skeletal muscle fiber development
is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048741 ! skeletal muscle fiber development
relationship: negatively_regulates GO:0048741 ! skeletal muscle fiber development

[Term]
id: GO:0048745
name: smooth muscle tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm]
is_a: GO:0060537 ! muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001135 ! smooth muscle tissue
relationship: results_in_development_of UBERON:0001135 ! smooth muscle tissue

[Term]
id: GO:0048749
name: compound eye development
namespace: biological_process
alt_id: GO:0007456
def: "The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye." [GOC:jid, GOC:mtg_sensu, Wikipedia:Eye]
synonym: "insect-type retina development" EXACT [PMID:11735386]
is_a: GO:0001654 ! eye development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000018 ! compound eye
relationship: results_in_development_of UBERON:0000018 ! compound eye

[Term]
id: GO:0048753
name: pigment granule organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule." [GOC:rc]
subset: goslim_pir
synonym: "pigment granule organisation" EXACT []
synonym: "pigment granule organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0016050 ! vesicle organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0048770 ! pigment granule
relationship: part_of GO:0033059 ! cellular pigmentation
relationship: results_in_organization_of GO:0048770 ! pigment granule

[Term]
id: GO:0048754
name: branching morphogenesis of an epithelial tube
namespace: biological_process
def: "The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder." [GOC:dgh, GOC:dph, GOC:jid]
synonym: "tubulogenesis" RELATED [GOC:dph, GOC:tb]
is_a: GO:0035239 ! tube morphogenesis
is_a: GO:0061138 ! morphogenesis of a branching epithelium
intersection_of: GO:0001763 ! morphogenesis of a branching structure
intersection_of: results_in_morphogenesis_of UBERON:0000025 ! tube
relationship: part_of GO:0060562 ! epithelial tube morphogenesis

[Term]
id: GO:0048755
name: branching morphogenesis of a nerve
namespace: biological_process
def: "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)." [GOC:dgh, GOC:dph, GOC:jid]
is_a: GO:0001763 ! morphogenesis of a branching structure
intersection_of: GO:0001763 ! morphogenesis of a branching structure
intersection_of: results_in_morphogenesis_of UBERON:0001021 ! nerve
relationship: part_of GO:0007399 ! nervous system development
relationship: results_in_morphogenesis_of UBERON:0001021 ! nerve

[Term]
id: GO:0048762
name: mesenchymal cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph, GOC:jid]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0008019 ! mesenchymal cell
relationship: part_of GO:0060485 ! mesenchyme development
relationship: results_in_acquisition_of_features_of CL:0008019 ! mesenchymal cell

[Term]
id: GO:0048770
name: pigment granule
namespace: cellular_component
def: "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes." [GOC:jid, GOC:mh]
is_a: GO:0031410 ! cytoplasmic vesicle

[Term]
id: GO:0048793
name: pronephros development
namespace: biological_process
def: "The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:bf, GOC:mtg_kidney_jan10, PMID:10535314, PMID:15968585, PMID:18322540, XAO:00002000, ZFA:0000151]
synonym: "pronephric kidney development" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0001822 ! kidney development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002120 ! pronephros
relationship: results_in_development_of UBERON:0002120 ! pronephros

[Term]
id: GO:0048799
name: animal organ maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions." [GOC:curators]
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0000062 ! organ
relationship: part_of GO:0048513 ! animal organ development
relationship: results_in_maturation_of UBERON:0000062 ! organ

[Term]
id: GO:0048806
name: genitalia development
namespace: biological_process
def: "The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure." [GOC:jid]
synonym: "genital development" EXACT []
is_a: GO:0048513 ! animal organ development
is_a: GO:0048608 ! reproductive structure development
relationship: part_of GO:0007548 ! sex differentiation

[Term]
id: GO:0048808
name: male genitalia morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of male genitalia are generated and organized." [GOC:ems, ISBN:0140512888]
synonym: "male genital morphogenesis" RELATED []
is_a: GO:0035112 ! genitalia morphogenesis
is_a: GO:0090598 ! male anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000079 ! male reproductive system
relationship: part_of GO:0030539 ! male genitalia development
relationship: results_in_morphogenesis_of UBERON:0000079 ! male reproductive system

[Term]
id: GO:0048812
name: neuron projection morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." [GOC:mah]
synonym: "neurite biosynthesis" NARROW []
synonym: "neurite formation" NARROW []
synonym: "neurite growth" NARROW []
synonym: "neurite morphogenesis" RELATED [GOC:dph, GOC:tb]
is_a: GO:0120039 ! plasma membrane bounded cell projection morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of GO:0043005 ! neuron projection
relationship: part_of GO:0031175 ! neuron projection development
relationship: results_in_morphogenesis_of GO:0043005 ! neuron projection

[Term]
id: GO:0048821
name: erythrocyte development
namespace: biological_process
def: "The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure." [GOC:devbiol]
synonym: "RBC development" EXACT [CL:0000232]
synonym: "red blood cell development" EXACT [CL:0000232]
is_a: GO:0061515 ! myeloid cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000232 ! erythrocyte
relationship: part_of GO:0030218 ! erythrocyte differentiation
relationship: results_in_development_of CL:0000232 ! erythrocyte

[Term]
id: GO:0048822
name: enucleate erythrocyte development
namespace: biological_process
def: "The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol]
synonym: "enucleate RBC development" EXACT [CL:0000232]
synonym: "enucleate red blood cell development" EXACT [CL:0000232]
is_a: GO:0048821 ! erythrocyte development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000595 ! enucleate erythrocyte
relationship: part_of GO:0043353 ! enucleate erythrocyte differentiation
relationship: results_in_development_of CL:0000595 ! enucleate erythrocyte

[Term]
id: GO:0048823
name: nucleate erythrocyte development
namespace: biological_process
def: "The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol]
synonym: "nucleate RBC development" EXACT [CL:0000232]
synonym: "nucleate red blood cell development" EXACT [CL:0000232]
is_a: GO:0048821 ! erythrocyte development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000562 ! nucleate erythrocyte
relationship: part_of GO:0043363 ! nucleate erythrocyte differentiation
relationship: results_in_development_of CL:0000562 ! nucleate erythrocyte

[Term]
id: GO:0048844
name: artery morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs." [GOC:dsf, PMID:16740480]
synonym: "arterial morphogenesis" EXACT []
synonym: "arteriogenesis" EXACT [GOC:mtg_heart]
is_a: GO:0048514 ! blood vessel morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001637 ! artery
relationship: part_of GO:0060840 ! artery development
relationship: results_in_morphogenesis_of UBERON:0001637 ! artery

[Term]
id: GO:0048845
name: venous blood vessel morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart." [GOC:dsf, PMID:16740480]
synonym: "vein morphogenesis" BROAD []
synonym: "venous morphogenesis" EXACT []
is_a: GO:0048514 ! blood vessel morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001638 ! vein
relationship: part_of GO:0060841 ! venous blood vessel development
relationship: results_in_morphogenesis_of UBERON:0001638 ! vein

[Term]
id: GO:0048854
name: brain morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dgh, GOC:jid]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000955 ! brain
relationship: part_of GO:0007420 ! brain development
relationship: results_in_morphogenesis_of UBERON:0000955 ! brain

[Term]
id: GO:0048856
name: anatomical structure development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021]
subset: gocheck_do_not_annotate
subset: goslim_chembl
subset: goslim_generic
subset: goslim_plant
synonym: "development of an anatomical structure" EXACT []
is_a: GO:0032502 ! developmental process
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure
relationship: results_in_development_of UBERON:0000061 ! anatomical structure
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI

[Term]
id: GO:0048857
name: neural nucleus development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma." [GO_REF:0000021]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000125 ! neural nucleus
relationship: results_in_development_of UBERON:0000125 ! neural nucleus

[Term]
id: GO:0048858
name: cell projection morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a cell projection are generated and organized." [GO_REF:0000021]
is_a: GO:0030030 ! cell projection organization
is_a: GO:0032989 ! cellular anatomical entity morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of GO:0042995 ! cell projection
relationship: part_of GO:0000902 ! cell morphogenesis
relationship: results_in_morphogenesis_of GO:0042995 ! cell projection

[Term]
id: GO:0048859
name: formation of anatomical boundary
namespace: biological_process
def: "The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0007651 ! anatomical junction
relationship: results_in_formation_of_anatomical_entity UBERON:0007651 ! anatomical junction

[Term]
id: GO:0048863
name: stem cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [CL:0000034, GOC:isa_complete]
xref: Wikipedia:Stem_cell_differentiation
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000034 ! stem cell
relationship: results_in_acquisition_of_features_of CL:0000034 ! stem cell
property_value: RO:0002161 NCBITaxon:4751

[Term]
id: GO:0048864
name: stem cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate." [CL:0000034, GOC:isa_complete]
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000034 ! stem cell
relationship: part_of GO:0048863 ! stem cell differentiation
relationship: results_in_development_of CL:0000034 ! stem cell

[Term]
id: GO:0048869
name: cellular developmental process
namespace: biological_process
def: "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." [GOC:isa_complete]
is_a: GO:0009987 ! cellular process
is_a: GO:0032502 ! developmental process

[Term]
id: GO:0048870
name: cell motility
namespace: biological_process
def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." [GOC:dgh, GOC:dph, GOC:isa_complete, GOC:mlg]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_prokaryote
synonym: "cell locomotion" EXACT []
synonym: "cell movement" RELATED []
synonym: "movement of a cell" EXACT []
is_a: GO:0009987 ! cellular process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI

[Term]
id: GO:0048871
name: multicellular organismal-level homeostasis
namespace: biological_process
def: "Any process involved in the maintenance of an internal steady state at the level of the multicellular organism." [GOC:isa_complete]
is_a: GO:0032501 ! multicellular organismal process
is_a: GO:0042592 ! homeostatic process

[Term]
id: GO:0048872
name: homeostasis of number of cells
namespace: biological_process
def: "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells." [GOC:isa_complete]
synonym: "cell population homeostasis" EXACT []
synonym: "homeostasis of cell number" EXACT [GOC:dph]
is_a: GO:0048871 ! multicellular organismal-level homeostasis
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI

[Term]
id: GO:0048880
name: sensory system development
namespace: biological_process
def: "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure." [GOC:dgh]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001032 ! sensory system
relationship: results_in_development_of UBERON:0001032 ! sensory system

[Term]
id: GO:0048934
name: peripheral nervous system neuron differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system." [GOC:dgh]
is_a: GO:0030182 ! neuron differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:2000032 ! peripheral nervous system neuron
relationship: part_of GO:0007422 ! peripheral nervous system development
relationship: results_in_acquisition_of_features_of CL:2000032 ! peripheral nervous system neuron

[Term]
id: GO:0048935
name: peripheral nervous system neuron development
namespace: biological_process
def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GOC:dgh]
is_a: GO:0048666 ! neuron development
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:2000032 ! peripheral nervous system neuron
relationship: part_of GO:0048934 ! peripheral nervous system neuron differentiation
relationship: results_in_development_of CL:2000032 ! peripheral nervous system neuron

[Term]
id: GO:0050000
name: chromosome localization
namespace: biological_process
def: "Any process in which a chromosome is transported to, or maintained in, a specific location." [GOC:ai]
synonym: "chromosome localisation" EXACT [GOC:mah]
synonym: "establishment and maintenance of chromosome localization" EXACT []
synonym: "establishment and maintenance of chromosome position" EXACT []
is_a: GO:0051640 ! organelle localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0005694 ! chromosome
relationship: has_primary_input GO:0005694 ! chromosome

[Term]
id: GO:0050432
name: catecholamine secretion
namespace: biological_process
def: "The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, GOC:ef]
is_a: GO:0032940 ! secretion by cell
is_a: GO:0051937 ! catecholamine transport
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input CHEBI:33567 ! catecholamine

[Term]
id: GO:0050433
name: regulation of catecholamine secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines." [GOC:ai]
is_a: GO:0051952 ! regulation of amine transport
is_a: GO:1903530 ! regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0050432 ! catecholamine secretion
relationship: regulates GO:0050432 ! catecholamine secretion

[Term]
id: GO:0050657
name: nucleic acid transport
namespace: biological_process
def: "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732]
is_a: GO:0015931 ! nucleobase-containing compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:33696 ! nucleic acid
relationship: has_primary_input CHEBI:33696 ! nucleic acid

[Term]
id: GO:0050658
name: RNA transport
namespace: biological_process
def: "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
is_a: GO:0050657 ! nucleic acid transport
is_a: GO:0051236 ! establishment of RNA localization
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid
relationship: has_primary_input CHEBI:33697 ! ribonucleic acid

[Term]
id: GO:0050670
name: regulation of lymphocyte proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of lymphocyte proliferation." [GOC:ai]
is_a: GO:0032944 ! regulation of mononuclear cell proliferation
is_a: GO:0051249 ! regulation of lymphocyte activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0046651 ! lymphocyte proliferation
relationship: regulates GO:0046651 ! lymphocyte proliferation

[Term]
id: GO:0050671
name: positive regulation of lymphocyte proliferation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of lymphocyte proliferation." [GOC:ai]
synonym: "activation of lymphocyte proliferation" NARROW []
synonym: "stimulation of lymphocyte proliferation" NARROW []
synonym: "up regulation of lymphocyte proliferation" EXACT []
synonym: "up-regulation of lymphocyte proliferation" EXACT []
synonym: "upregulation of lymphocyte proliferation" EXACT []
is_a: GO:0032946 ! positive regulation of mononuclear cell proliferation
is_a: GO:0050670 ! regulation of lymphocyte proliferation
is_a: GO:0051251 ! positive regulation of lymphocyte activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0046651 ! lymphocyte proliferation
relationship: positively_regulates GO:0046651 ! lymphocyte proliferation

[Term]
id: GO:0050672
name: negative regulation of lymphocyte proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation." [GOC:ai]
synonym: "down regulation of lymphocyte proliferation" EXACT []
synonym: "down-regulation of lymphocyte proliferation" EXACT []
synonym: "downregulation of lymphocyte proliferation" EXACT []
synonym: "inhibition of lymphocyte proliferation" NARROW []
is_a: GO:0032945 ! negative regulation of mononuclear cell proliferation
is_a: GO:0050670 ! regulation of lymphocyte proliferation
is_a: GO:0051250 ! negative regulation of lymphocyte activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0046651 ! lymphocyte proliferation
relationship: negatively_regulates GO:0046651 ! lymphocyte proliferation

[Term]
id: GO:0050673
name: epithelial cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances." [ISBN:0721662544]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000066 ! epithelial cell
relationship: acts_on_population_of CL:0000066 ! epithelial cell

[Term]
id: GO:0050678
name: regulation of epithelial cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation." [GOC:ai]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0050673 ! epithelial cell proliferation
relationship: regulates GO:0050673 ! epithelial cell proliferation

[Term]
id: GO:0050679
name: positive regulation of epithelial cell proliferation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of epithelial cell proliferation." [GOC:ai]
synonym: "activation of epithelial cell proliferation" NARROW []
synonym: "stimulation of epithelial cell proliferation" NARROW []
synonym: "up regulation of epithelial cell proliferation" EXACT []
synonym: "up-regulation of epithelial cell proliferation" EXACT []
synonym: "upregulation of epithelial cell proliferation" EXACT []
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0050678 ! regulation of epithelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0050673 ! epithelial cell proliferation
relationship: positively_regulates GO:0050673 ! epithelial cell proliferation

[Term]
id: GO:0050680
name: negative regulation of epithelial cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation." [GOC:ai]
synonym: "down regulation of epithelial cell proliferation" EXACT []
synonym: "down-regulation of epithelial cell proliferation" EXACT []
synonym: "downregulation of epithelial cell proliferation" EXACT []
synonym: "inhibition of epithelial cell proliferation" NARROW []
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0050678 ! regulation of epithelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0050673 ! epithelial cell proliferation
relationship: negatively_regulates GO:0050673 ! epithelial cell proliferation

[Term]
id: GO:0050708
name: regulation of protein secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai]
is_a: GO:0051223 ! regulation of protein transport
is_a: GO:1903530 ! regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009306 ! protein secretion
relationship: regulates GO:0009306 ! protein secretion

[Term]
id: GO:0050709
name: negative regulation of protein secretion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai]
synonym: "down regulation of protein secretion" EXACT []
synonym: "down-regulation of protein secretion" EXACT []
synonym: "downregulation of protein secretion" EXACT []
synonym: "inhibition of protein secretion" NARROW []
is_a: GO:0050708 ! regulation of protein secretion
is_a: GO:0051224 ! negative regulation of protein transport
is_a: GO:1903531 ! negative regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009306 ! protein secretion
relationship: negatively_regulates GO:0009306 ! protein secretion

[Term]
id: GO:0050714
name: positive regulation of protein secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai]
synonym: "activation of protein secretion" NARROW []
synonym: "stimulation of protein secretion" NARROW []
synonym: "up regulation of protein secretion" EXACT []
synonym: "up-regulation of protein secretion" EXACT []
synonym: "upregulation of protein secretion" EXACT []
is_a: GO:0050708 ! regulation of protein secretion
is_a: GO:0051222 ! positive regulation of protein transport
is_a: GO:1903532 ! positive regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009306 ! protein secretion
relationship: positively_regulates GO:0009306 ! protein secretion

[Term]
id: GO:0050727
name: regulation of inflammatory response
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents." [GOC:ai]
is_a: GO:0031347 ! regulation of defense response
is_a: GO:0032101 ! regulation of response to external stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006954 ! inflammatory response
relationship: regulates GO:0006954 ! inflammatory response

[Term]
id: GO:0050728
name: negative regulation of inflammatory response
namespace: biological_process
alt_id: GO:0030236
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response." [GOC:ai]
synonym: "anti-inflammatory response" EXACT []
synonym: "down regulation of inflammatory response" EXACT []
synonym: "down-regulation of inflammatory response" EXACT []
synonym: "downregulation of inflammatory response" EXACT []
synonym: "inhibition of inflammatory response" NARROW []
is_a: GO:0031348 ! negative regulation of defense response
is_a: GO:0032102 ! negative regulation of response to external stimulus
is_a: GO:0050727 ! regulation of inflammatory response
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006954 ! inflammatory response
relationship: negatively_regulates GO:0006954 ! inflammatory response

[Term]
id: GO:0050729
name: positive regulation of inflammatory response
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the inflammatory response." [GOC:ai]
synonym: "activation of inflammatory response" NARROW []
synonym: "stimulation of inflammatory response" NARROW []
synonym: "up regulation of inflammatory response" EXACT []
synonym: "up-regulation of inflammatory response" EXACT []
synonym: "upregulation of inflammatory response" EXACT []
is_a: GO:0031349 ! positive regulation of defense response
is_a: GO:0032103 ! positive regulation of response to external stimulus
is_a: GO:0050727 ! regulation of inflammatory response
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006954 ! inflammatory response
relationship: positively_regulates GO:0006954 ! inflammatory response

[Term]
id: GO:0050764
name: regulation of phagocytosis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material." [GOC:ai]
is_a: GO:0030100 ! regulation of endocytosis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006909 ! phagocytosis
relationship: regulates GO:0006909 ! phagocytosis
property_value: RO:0002161 NCBITaxon:147537

[Term]
id: GO:0050765
name: negative regulation of phagocytosis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis." [GOC:ai]
synonym: "down regulation of phagocytosis" EXACT []
synonym: "down-regulation of phagocytosis" EXACT []
synonym: "downregulation of phagocytosis" EXACT []
synonym: "inhibition of phagocytosis" NARROW []
is_a: GO:0045806 ! negative regulation of endocytosis
is_a: GO:0050764 ! regulation of phagocytosis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006909 ! phagocytosis
relationship: negatively_regulates GO:0006909 ! phagocytosis

[Term]
id: GO:0050766
name: positive regulation of phagocytosis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of phagocytosis." [GOC:ai]
synonym: "activation of phagocytosis" NARROW []
synonym: "stimulation of phagocytosis" NARROW []
synonym: "up regulation of phagocytosis" EXACT []
synonym: "up-regulation of phagocytosis" EXACT []
synonym: "upregulation of phagocytosis" EXACT []
is_a: GO:0045807 ! positive regulation of endocytosis
is_a: GO:0050764 ! regulation of phagocytosis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006909 ! phagocytosis
relationship: positively_regulates GO:0006909 ! phagocytosis

[Term]
id: GO:0050767
name: regulation of neurogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." [GOC:ai]
is_a: GO:0051960 ! regulation of nervous system development
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0022008 ! neurogenesis
relationship: regulates GO:0022008 ! neurogenesis

[Term]
id: GO:0050768
name: negative regulation of neurogenesis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai]
synonym: "down regulation of neurogenesis" EXACT []
synonym: "down-regulation of neurogenesis" EXACT []
synonym: "downregulation of neurogenesis" EXACT []
synonym: "inhibition of neurogenesis" NARROW []
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0050767 ! regulation of neurogenesis
is_a: GO:0051961 ! negative regulation of nervous system development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0022008 ! neurogenesis
relationship: negatively_regulates GO:0022008 ! neurogenesis

[Term]
id: GO:0050769
name: positive regulation of neurogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai]
synonym: "activation of neurogenesis" NARROW []
synonym: "stimulation of neurogenesis" NARROW []
synonym: "up regulation of neurogenesis" EXACT []
synonym: "up-regulation of neurogenesis" EXACT []
synonym: "upregulation of neurogenesis" EXACT []
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0050767 ! regulation of neurogenesis
is_a: GO:0051962 ! positive regulation of nervous system development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0022008 ! neurogenesis
relationship: positively_regulates GO:0022008 ! neurogenesis

[Term]
id: GO:0050776
name: regulation of immune response
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai]
is_a: GO:0002682 ! regulation of immune system process
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006955 ! immune response
relationship: regulates GO:0006955 ! immune response

[Term]
id: GO:0050777
name: negative regulation of immune response
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai]
synonym: "down regulation of immune response" EXACT []
synonym: "down-regulation of immune response" EXACT []
synonym: "downregulation of immune response" EXACT []
synonym: "inhibition of immune response" NARROW []
is_a: GO:0002683 ! negative regulation of immune system process
is_a: GO:0048585 ! negative regulation of response to stimulus
is_a: GO:0050776 ! regulation of immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006955 ! immune response
relationship: negatively_regulates GO:0006955 ! immune response

[Term]
id: GO:0050778
name: positive regulation of immune response
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai]
synonym: "stimulation of immune response" NARROW []
synonym: "up regulation of immune response" EXACT []
synonym: "up-regulation of immune response" EXACT []
synonym: "upregulation of immune response" EXACT []
is_a: GO:0002684 ! positive regulation of immune system process
is_a: GO:0048584 ! positive regulation of response to stimulus
is_a: GO:0050776 ! regulation of immune response
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006955 ! immune response
relationship: positively_regulates GO:0006955 ! immune response

[Term]
id: GO:0050789
name: regulation of biological process
namespace: biological_process
alt_id: GO:0050791
def: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:ai, GOC:go_curators]
subset: gocheck_do_not_annotate
subset: goslim_candida
subset: goslim_pir
synonym: "regulation of physiological process" EXACT []
is_a: GO:0065007 ! biological regulation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008150 ! biological process
relationship: regulates GO:0008150 ! biological process

[Term]
id: GO:0050790
name: regulation of catalytic activity
namespace: biological_process
alt_id: GO:0048552
def: "Any process that modulates the activity of an enzyme." [GOC:ai, GOC:ebc, GOC:vw]
subset: gocheck_do_not_annotate
subset: goslim_chembl
synonym: "regulation of enzyme activity" EXACT []
synonym: "regulation of metalloenzyme activity" NARROW []
is_a: GO:0065009 ! regulation of molecular function
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003824 ! catalytic activity
relationship: regulates GO:0003824 ! catalytic activity

[Term]
id: GO:0050793
name: regulation of developmental process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:go_curators]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032502 ! developmental process
relationship: regulates GO:0032502 ! developmental process

[Term]
id: GO:0050794
name: regulation of cellular process
namespace: biological_process
alt_id: GO:0051244
def: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators]
subset: gocheck_do_not_annotate
synonym: "regulation of cellular physiological process" EXACT []
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009987 ! cellular process
relationship: regulates GO:0009987 ! cellular process

[Term]
id: GO:0050795
name: regulation of behavior
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:go_curators, GOC:pr]
synonym: "regulation of behaviour" EXACT []
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007610 ! behavior
relationship: regulates GO:0007610 ! behavior

[Term]
id: GO:0050796
name: regulation of insulin secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the regulated release of insulin." [GOC:ai]
is_a: GO:0050708 ! regulation of protein secretion
is_a: GO:0090276 ! regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030073 ! insulin secretion
relationship: regulates GO:0030073 ! insulin secretion

[Term]
id: GO:0050803
name: regulation of synapse structure or activity
namespace: biological_process
def: "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai]
relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa

[Term]
id: GO:0050804
name: modulation of chemical synaptic transmission
namespace: biological_process
def: "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." [GOC:ai]
subset: goslim_synapse
synonym: "modulation of synaptic transmission" BROAD []
synonym: "regulation of chemical synaptic transmission" EXACT []
synonym: "regulation of synaptic transmission" EXACT []
is_a: GO:0099177 ! regulation of trans-synaptic signaling
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007268 ! chemical synaptic transmission
relationship: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0050805
name: negative regulation of synaptic transmission
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai]
synonym: "down regulation of synaptic transmission" EXACT []
synonym: "down-regulation of synaptic transmission" EXACT []
synonym: "downregulation of synaptic transmission" EXACT []
synonym: "inhibition of synaptic transmission" NARROW []
is_a: GO:0010648 ! negative regulation of cell communication
is_a: GO:0023057 ! negative regulation of signaling
is_a: GO:0050804 ! modulation of chemical synaptic transmission
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007268 ! chemical synaptic transmission
relationship: negatively_regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0050806
name: positive regulation of synaptic transmission
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai]
synonym: "activation of synaptic transmission" NARROW []
synonym: "stimulation of synaptic transmission" NARROW []
synonym: "up regulation of synaptic transmission" EXACT []
synonym: "up-regulation of synaptic transmission" EXACT []
synonym: "upregulation of synaptic transmission" EXACT []
is_a: GO:0010647 ! positive regulation of cell communication
is_a: GO:0023056 ! positive regulation of signaling
is_a: GO:0050804 ! modulation of chemical synaptic transmission
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007268 ! chemical synaptic transmission
relationship: positively_regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0050807
name: regulation of synapse organization
namespace: biological_process
def: "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:dph, GOC:tb]
subset: goslim_synapse
synonym: "regulation of synapse organisation" EXACT [GOC:mah]
synonym: "regulation of synapse organization and biogenesis" RELATED [GOC:mah]
synonym: "regulation of synapse structure" EXACT []
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0050808 ! synapse organization
relationship: part_of GO:0050803 ! regulation of synapse structure or activity
relationship: regulates GO:0050808 ! synapse organization

[Term]
id: GO:0050808
name: synapse organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:pr]
subset: goslim_drosophila
subset: goslim_synapse
synonym: "synapse development" RELATED [GOC:aruk]
synonym: "synapse morphogenesis" RELATED [GOC:BHF]
synonym: "synapse organisation" EXACT []
synonym: "synapse organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0034330 ! cell junction organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_organization_of GO:0045202 ! synapse
relationship: results_in_organization_of GO:0045202 ! synapse

[Term]
id: GO:0050810
name: regulation of steroid biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:ai]
synonym: "regulation of steroid anabolism" EXACT []
synonym: "regulation of steroid biosynthesis" EXACT []
synonym: "regulation of steroid formation" EXACT []
synonym: "regulation of steroid synthesis" EXACT []
synonym: "regulation of steroidogenesis" EXACT []
is_a: GO:0019218 ! regulation of steroid metabolic process
is_a: GO:0046890 ! regulation of lipid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006694 ! steroid biosynthetic process
relationship: regulates GO:0006694 ! steroid biosynthetic process

[Term]
id: GO:0050832
name: defense response to fungus
namespace: biological_process
alt_id: GO:0009623
alt_id: GO:0009817
alt_id: GO:0042831
def: "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism." [GOC:ai]
synonym: "defence response to fungi" EXACT []
synonym: "defence response to fungus" EXACT []
synonym: "defense response to fungi" EXACT []
synonym: "defense response to fungus, incompatible interaction" NARROW []
synonym: "resistance response to pathogenic fungi" NARROW []
synonym: "resistance response to pathogenic fungus" NARROW []
synonym: "response to parasitic fungi" NARROW []
synonym: "response to parasitic fungus" NARROW []
is_a: GO:0009620 ! response to fungus
is_a: GO:0098542 ! defense response to other organism
intersection_of: GO:0006952 ! defense response
intersection_of: has_primary_input NCBITaxon:4751 ! Fungi

[Term]
id: GO:0050863
name: regulation of T cell activation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of T cell activation." [GOC:ai]
synonym: "regulation of T lymphocyte activation" EXACT []
synonym: "regulation of T-cell activation" EXACT []
synonym: "regulation of T-lymphocyte activation" EXACT []
is_a: GO:0051249 ! regulation of lymphocyte activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042110 ! T cell activation
relationship: regulates GO:0042110 ! T cell activation

[Term]
id: GO:0050865
name: regulation of cell activation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:ai]
is_a: GO:0050794 ! regulation of cellular process
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001775 ! cell activation
relationship: regulates GO:0001775 ! cell activation

[Term]
id: GO:0050866
name: negative regulation of cell activation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation." [GOC:ai]
synonym: "down regulation of cell activation" EXACT []
synonym: "down-regulation of cell activation" EXACT []
synonym: "downregulation of cell activation" EXACT []
synonym: "inhibition of cell activation" NARROW []
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0050865 ! regulation of cell activation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001775 ! cell activation
relationship: negatively_regulates GO:0001775 ! cell activation

[Term]
id: GO:0050867
name: positive regulation of cell activation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of activation." [GOC:ai]
synonym: "activation of cell activation" NARROW []
synonym: "stimulation of cell activation" NARROW []
synonym: "up regulation of cell activation" EXACT []
synonym: "up-regulation of cell activation" EXACT []
synonym: "upregulation of cell activation" EXACT []
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0050865 ! regulation of cell activation
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001775 ! cell activation
relationship: positively_regulates GO:0001775 ! cell activation

[Term]
id: GO:0050868
name: negative regulation of T cell activation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation." [GOC:ai]
synonym: "down regulation of T cell activation" EXACT []
synonym: "down-regulation of T cell activation" EXACT []
synonym: "downregulation of T cell activation" EXACT []
synonym: "inhibition of T cell activation" NARROW []
synonym: "negative regulation of T lymphocyte activation" EXACT []
synonym: "negative regulation of T-cell activation" EXACT []
synonym: "negative regulation of T-lymphocyte activation" EXACT []
is_a: GO:0050863 ! regulation of T cell activation
is_a: GO:0051250 ! negative regulation of lymphocyte activation
is_a: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042110 ! T cell activation
relationship: negatively_regulates GO:0042110 ! T cell activation

[Term]
id: GO:0050870
name: positive regulation of T cell activation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of T cell activation." [GOC:ai]
synonym: "activation of T cell activation" NARROW []
synonym: "positive regulation of T lymphocyte activation" EXACT []
synonym: "positive regulation of T-cell activation" EXACT []
synonym: "positive regulation of T-lymphocyte activation" EXACT []
synonym: "stimulation of T cell activation" NARROW []
synonym: "up regulation of T cell activation" EXACT []
synonym: "up-regulation of T cell activation" EXACT []
synonym: "upregulation of T cell activation" EXACT []
is_a: GO:0050863 ! regulation of T cell activation
is_a: GO:0051251 ! positive regulation of lymphocyte activation
is_a: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0042110 ! T cell activation
relationship: positively_regulates GO:0042110 ! T cell activation

[Term]
id: GO:0050877
name: nervous system process
namespace: biological_process
def: "A organ system process carried out by any of the organs or tissues of neurological system." [GOC:ai, GOC:mtg_cardio]
subset: goslim_agr
subset: goslim_chembl
subset: goslim_flybase_ribbon
subset: goslim_generic
subset: goslim_pir
synonym: "neurological system process" EXACT []
synonym: "neurophysiological process" EXACT []
synonym: "pan-neural process" RELATED []
is_a: GO:0003008 ! system process
intersection_of: GO:0003008 ! system process
intersection_of: has_participant UBERON:0001016 ! nervous system
relationship: has_participant UBERON:0001016 ! nervous system
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13824" xsd:anyURI

[Term]
id: GO:0050878
name: regulation of body fluid levels
namespace: biological_process
def: "Any process that modulates the levels of body fluids." [GOC:ai, GOC:dph, GOC:tb]
subset: goslim_pir

[Term]
id: GO:0050879
name: multicellular organismal movement
namespace: biological_process
def: "Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism." [GOC:dph, GOC:mtg_muscle, GOC:tb]
subset: goslim_pir
is_a: GO:0032501 ! multicellular organismal process

[Term]
id: GO:0050881
name: musculoskeletal movement
namespace: biological_process
def: "The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system." [GOC:dph]
is_a: GO:0050879 ! multicellular organismal movement
is_a: GO:0050905 ! neuromuscular process

[Term]
id: GO:0050886
name: endocrine process
namespace: biological_process
def: "The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [ISBN:0721662544]
subset: goslim_generic
subset: goslim_pir
synonym: "endocrine physiological process" EXACT []
synonym: "endocrine physiology" EXACT []
is_a: GO:0003008 ! system process

[Term]
id: GO:0050890
name: cognition
namespace: biological_process
def: "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." [ISBN:0721619908]
subset: goslim_drosophila
xref: Wikipedia:Cognition
is_a: GO:0050877 ! nervous system process

[Term]
id: GO:0050896
name: response to stimulus
namespace: biological_process
alt_id: GO:0051869
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
subset: goslim_agr
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_pir
subset: goslim_prokaryote
synonym: "physiological response to stimulus" EXACT []
is_a: GO:0008150 ! biological process

[Term]
id: GO:0050900
name: leukocyte migration
namespace: biological_process
def: "The movement of a leukocyte within or between different tissues and organs of the body." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538]
synonym: "immune cell migration" EXACT []
synonym: "immune cell trafficking" EXACT []
synonym: "leucocyte migration" EXACT []
synonym: "leucocyte trafficking" EXACT []
synonym: "leukocyte trafficking" EXACT []
is_a: GO:0002376 ! immune system process
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000738 ! leukocyte
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: results_in_movement_of CL:0000738 ! leukocyte

[Term]
id: GO:0050905
name: neuromuscular process
namespace: biological_process
def: "Any process pertaining to the functions of the nervous and muscular systems of an organism." [GOC:ai]
synonym: "neuromotor process" EXACT []
synonym: "neuromuscular physiological process" EXACT []
is_a: GO:0050877 ! nervous system process

[Term]
id: GO:0050906
name: detection of stimulus involved in sensory perception
namespace: biological_process
def: "The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph]
synonym: "sensory detection of stimulus" EXACT []
synonym: "sensory perception, sensory transduction of stimulus" EXACT []
synonym: "sensory perception, stimulus detection" EXACT []
synonym: "sensory transduction" EXACT []
xref: Wikipedia:Transduction_(physiology)
is_a: GO:0051606 ! detection of stimulus
intersection_of: GO:0051606 ! detection of stimulus
intersection_of: part_of GO:0007600 ! sensory perception
relationship: part_of GO:0007600 ! sensory perception

[Term]
id: GO:0050907
name: detection of chemical stimulus involved in sensory perception
namespace: biological_process
def: "The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos]
synonym: "sensory detection of chemical stimulus" EXACT []
synonym: "sensory detection of chemical stimulus during sensory perception" EXACT []
synonym: "sensory perception, sensory detection of chemical stimulus" EXACT []
synonym: "sensory perception, sensory transduction of chemical stimulus" EXACT []
synonym: "sensory transduction of chemical stimulus" EXACT []
synonym: "sensory transduction of chemical stimulus during sensory perception" EXACT []
is_a: GO:0009593 ! detection of chemical stimulus
is_a: GO:0050906 ! detection of stimulus involved in sensory perception
intersection_of: GO:0009593 ! detection of chemical stimulus
intersection_of: part_of GO:0007600 ! sensory perception
relationship: part_of GO:0007606 ! sensory perception of chemical stimulus

[Term]
id: GO:0050908
name: detection of light stimulus involved in visual perception
namespace: biological_process
def: "The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos]
synonym: "sensory detection of light during visual perception" EXACT []
synonym: "sensory detection of light stimulus during visual perception" EXACT []
synonym: "sensory transduction of light during visual perception" EXACT []
synonym: "sensory transduction of light stimulus during visual perception" EXACT []
synonym: "visual perception, detection of light stimulus" EXACT []
synonym: "visual perception, sensory transduction during perception of light" EXACT []
synonym: "visual perception, sensory transduction of light stimulus" EXACT []
is_a: GO:0009584 ! detection of visible light
is_a: GO:0050962 ! detection of light stimulus involved in sensory perception
intersection_of: GO:0009583 ! detection of light stimulus
intersection_of: part_of GO:0007601 ! visual perception
relationship: part_of GO:0007601 ! visual perception

[Term]
id: GO:0050931
name: pigment cell differentiation
namespace: biological_process
alt_id: GO:0043357
alt_id: GO:0043358
def: "The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte." [GOC:dgh]
comment: Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore.
synonym: "chromatophore differentiation" EXACT []
synonym: "pigmented cell differentiation" EXACT []
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000147 ! pigment cell
relationship: part_of GO:0048066 ! developmental pigmentation
relationship: results_in_acquisition_of_features_of CL:0000147 ! pigment cell

[Term]
id: GO:0050932
name: regulation of pigment cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of pigmented cell differentiation." [GOC:ai]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0050931 ! pigment cell differentiation
relationship: regulates GO:0050931 ! pigment cell differentiation

[Term]
id: GO:0050941
name: negative regulation of pigment cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation." [GOC:ai]
synonym: "down regulation of pigment cell differentiation" EXACT []
synonym: "down-regulation of pigment cell differentiation" EXACT []
synonym: "downregulation of pigment cell differentiation" EXACT []
synonym: "inhibition of pigment cell differentiation" NARROW []
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0048086 ! negative regulation of developmental pigmentation
is_a: GO:0050932 ! regulation of pigment cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0050931 ! pigment cell differentiation
relationship: negatively_regulates GO:0050931 ! pigment cell differentiation

[Term]
id: GO:0050942
name: positive regulation of pigment cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation." [GOC:ai]
synonym: "activation of pigment cell differentiation" NARROW []
synonym: "stimulation of pigment cell differentiation" NARROW []
synonym: "up regulation of pigment cell differentiation" EXACT []
synonym: "up-regulation of pigment cell differentiation" EXACT []
synonym: "upregulation of pigment cell differentiation" EXACT []
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0048087 ! positive regulation of developmental pigmentation
is_a: GO:0050932 ! regulation of pigment cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0050931 ! pigment cell differentiation
relationship: positively_regulates GO:0050931 ! pigment cell differentiation

[Term]
id: GO:0050952
name: sensory perception of electrical stimulus
namespace: biological_process
def: "The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai]
is_a: GO:0007600 ! sensory perception

[Term]
id: GO:0050953
name: sensory perception of light stimulus
namespace: biological_process
def: "The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai]
is_a: GO:0007600 ! sensory perception

[Term]
id: GO:0050954
name: sensory perception of mechanical stimulus
namespace: biological_process
def: "The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai]
synonym: "chemi-mechanical coupling" RELATED []
synonym: "mechanosensory perception" EXACT []
synonym: "perception of mechanical stimulus" EXACT []
is_a: GO:0007600 ! sensory perception

[Term]
id: GO:0050956
name: electroception
namespace: biological_process
def: "The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location." [GOC:ai, PMID:10210663, Wikipedia:Electroreception]
synonym: "electroception sense" EXACT []
synonym: "electroceptive sense" EXACT []
xref: Wikipedia:Electroreception
is_a: GO:0050952 ! sensory perception of electrical stimulus

[Term]
id: GO:0050962
name: detection of light stimulus involved in sensory perception
namespace: biological_process
def: "The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light." [GOC:ai, GOC:dos]
synonym: "sensory detection of light stimulus" EXACT []
synonym: "sensory detection of light stimulus during sensory perception" EXACT []
synonym: "sensory perception, sensory detection of light stimulus" EXACT []
synonym: "sensory perception, sensory transduction of light stimulus" EXACT []
synonym: "sensory transduction of light stimulus" EXACT []
synonym: "sensory transduction of light stimulus during sensory perception" EXACT []
is_a: GO:0009583 ! detection of light stimulus
is_a: GO:0050906 ! detection of stimulus involved in sensory perception
intersection_of: GO:0009583 ! detection of light stimulus
intersection_of: part_of GO:0007600 ! sensory perception
relationship: part_of GO:0050953 ! sensory perception of light stimulus

[Term]
id: GO:0050963
name: detection of electrical stimulus involved in sensory perception
namespace: biological_process
def: "The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos]
synonym: "sensory detection of electrical stimulus" EXACT []
synonym: "sensory detection of electrical stimulus during sensory perception" EXACT []
synonym: "sensory perception, sensory detection of electrical stimulus" EXACT []
synonym: "sensory perception, sensory transduction of electrical stimulus" EXACT []
synonym: "sensory transduction of electrical stimulus" EXACT []
synonym: "sensory transduction of electrical stimulus during sensory perception" EXACT []
is_a: GO:0050906 ! detection of stimulus involved in sensory perception
is_a: GO:0050981 ! detection of electrical stimulus
intersection_of: GO:0050981 ! detection of electrical stimulus
intersection_of: part_of GO:0007600 ! sensory perception
relationship: part_of GO:0050952 ! sensory perception of electrical stimulus

[Term]
id: GO:0050964
name: detection of electrical stimulus involved in electroception
namespace: biological_process
def: "The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos]
synonym: "detection of electrical stimulus during electroreception" RELATED [GOC:dph, GOC:tb]
synonym: "electroception, detection of electrical stimulus" EXACT []
synonym: "electroception, sensory detection of electrical stimulus" EXACT []
synonym: "electroception, sensory transduction" EXACT []
synonym: "electroception, sensory transduction of electrical stimulus" EXACT []
synonym: "sensory detection of electrical stimulus during electroception" RELATED []
synonym: "sensory transduction of electrical stimulus during electroception" RELATED []
is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception
intersection_of: GO:0050981 ! detection of electrical stimulus
intersection_of: part_of GO:0050956 ! electroception
relationship: part_of GO:0050956 ! electroception

[Term]
id: GO:0050967
name: detection of electrical stimulus involved in sensory perception of pain
namespace: biological_process
def: "The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph, GOC:tb]
synonym: "detection of electrical stimulus during sensory perception of pain" RELATED [GOC:dph, GOC:tb]
synonym: "perception of pain, detection of electrical stimulus" EXACT []
synonym: "perception of pain, sensory detection of electrical stimulus" EXACT []
synonym: "perception of pain, sensory transduction of electrical stimulus" EXACT []
synonym: "sensory detection of electrical stimulus during perception of pain" RELATED []
synonym: "sensory transduction of electrical stimulus during perception of pain" RELATED []
is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception
is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain
intersection_of: GO:0050981 ! detection of electrical stimulus
intersection_of: part_of GO:0019233 ! sensory perception of pain

[Term]
id: GO:0050968
name: detection of chemical stimulus involved in sensory perception of pain
namespace: biological_process
def: "The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal." [GOC:ai]
synonym: "chemical nociception" RELATED [GOC:pr]
synonym: "perception of pain, detection of chemical stimulus" EXACT []
synonym: "perception of pain, sensory detection of chemical stimulus" EXACT []
synonym: "perception of pain, sensory transduction of chemical stimulus" EXACT []
synonym: "sensory detection of chemical stimulus during perception of pain" EXACT []
synonym: "sensory transduction of chemical stimulus during perception of pain" EXACT []
is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception
is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain
intersection_of: GO:0009593 ! detection of chemical stimulus
intersection_of: part_of GO:0019233 ! sensory perception of pain

[Term]
id: GO:0050975
name: sensory perception of touch
namespace: biological_process
def: "The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)." [GOC:ai]
synonym: "perception of touch" EXACT []
synonym: "tactile sense" EXACT []
synonym: "taction" EXACT []
synonym: "tactition" EXACT []
xref: Wikipedia:Touch
is_a: GO:0050954 ! sensory perception of mechanical stimulus

[Term]
id: GO:0050981
name: detection of electrical stimulus
namespace: biological_process
def: "The series of events by which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos]
is_a: GO:0009582 ! detection of abiotic stimulus
is_a: GO:0051602 ! response to electrical stimulus

[Term]
id: GO:0050994
name: regulation of lipid catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai]
synonym: "regulation of lipid breakdown" EXACT []
synonym: "regulation of lipid catabolism" EXACT []
synonym: "regulation of lipid degradation" EXACT []
is_a: GO:0009894 ! regulation of catabolic process
is_a: GO:0019216 ! regulation of lipid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016042 ! lipid catabolic process
relationship: regulates GO:0016042 ! lipid catabolic process

[Term]
id: GO:0050995
name: negative regulation of lipid catabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai]
synonym: "down regulation of lipid catabolic process" EXACT []
synonym: "down-regulation of lipid catabolic process" EXACT []
synonym: "downregulation of lipid catabolic process" EXACT []
synonym: "inhibition of lipid catabolic process" NARROW []
synonym: "negative regulation of lipid breakdown" EXACT []
synonym: "negative regulation of lipid catabolism" EXACT []
synonym: "negative regulation of lipid degradation" EXACT []
is_a: GO:0009895 ! negative regulation of catabolic process
is_a: GO:0045833 ! negative regulation of lipid metabolic process
is_a: GO:0050994 ! regulation of lipid catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0016042 ! lipid catabolic process
relationship: negatively_regulates GO:0016042 ! lipid catabolic process

[Term]
id: GO:0050996
name: positive regulation of lipid catabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai]
synonym: "activation of lipid catabolic process" NARROW []
synonym: "positive regulation of lipid breakdown" EXACT []
synonym: "positive regulation of lipid catabolism" EXACT []
synonym: "positive regulation of lipid degradation" EXACT []
synonym: "stimulation of lipid catabolic process" NARROW []
synonym: "up regulation of lipid catabolic process" EXACT []
synonym: "up-regulation of lipid catabolic process" EXACT []
synonym: "upregulation of lipid catabolic process" EXACT []
is_a: GO:0009896 ! positive regulation of catabolic process
is_a: GO:0045834 ! positive regulation of lipid metabolic process
is_a: GO:0050994 ! regulation of lipid catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0016042 ! lipid catabolic process
relationship: positively_regulates GO:0016042 ! lipid catabolic process

[Term]
id: GO:0051017
name: actin filament bundle assembly
namespace: biological_process
alt_id: GO:0045011
def: "The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:ai]
synonym: "actin bundling activity" RELATED []
synonym: "actin cable assembly" RELATED [GOC:mah]
synonym: "actin cable formation" RELATED [GOC:mah]
is_a: GO:0022607 ! cellular component assembly
is_a: GO:0061572 ! actin filament bundle organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0032432 ! actin filament bundle
relationship: results_in_assembly_of GO:0032432 ! actin filament bundle

[Term]
id: GO:0051027
name: DNA transport
namespace: biological_process
def: "The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
is_a: GO:0050657 ! nucleic acid transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid
relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid

[Term]
id: GO:0051032
name: nucleic acid transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information." [GOC:ai]
is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity
is_a: GO:0022884 ! macromolecule transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:33696 ! nucleic acid
relationship: has_primary_input CHEBI:33696 ! nucleic acid
relationship: part_of GO:0050657 ! nucleic acid transport

[Term]
id: GO:0051033
name: RNA transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other." [GOC:ai]
xref: Reactome:R-HSA-203906 "Exportin complex translocates pre-miRNA to cytosol"
is_a: GO:0051032 ! nucleic acid transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid
relationship: has_primary_input CHEBI:33697 ! ribonucleic acid
relationship: part_of GO:0050658 ! RNA transport

[Term]
id: GO:0051035
name: DNA transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other." [GOC:ai]
is_a: GO:0051032 ! nucleic acid transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid
relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid
relationship: part_of GO:0051027 ! DNA transport

[Term]
id: GO:0051046
name: regulation of secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai]
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0046903 ! secretion
relationship: regulates GO:0046903 ! secretion

[Term]
id: GO:0051047
name: positive regulation of secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai]
synonym: "activation of secretion" NARROW []
synonym: "stimulation of secretion" NARROW []
synonym: "up regulation of secretion" EXACT []
synonym: "up-regulation of secretion" EXACT []
synonym: "upregulation of secretion" EXACT []
is_a: GO:0051046 ! regulation of secretion
is_a: GO:0051050 ! positive regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0046903 ! secretion
relationship: positively_regulates GO:0046903 ! secretion

[Term]
id: GO:0051048
name: negative regulation of secretion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai]
synonym: "down regulation of secretion" EXACT []
synonym: "down-regulation of secretion" EXACT []
synonym: "downregulation of secretion" EXACT []
synonym: "inhibition of secretion" NARROW []
is_a: GO:0051046 ! regulation of secretion
is_a: GO:0051051 ! negative regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0046903 ! secretion
relationship: negatively_regulates GO:0046903 ! secretion

[Term]
id: GO:0051049
name: regulation of transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
subset: goslim_yeast
is_a: GO:0032879 ! regulation of localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006810 ! transport
relationship: regulates GO:0006810 ! transport

[Term]
id: GO:0051050
name: positive regulation of transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "activation of transport" NARROW []
synonym: "stimulation of transport" NARROW []
synonym: "up regulation of transport" EXACT []
synonym: "up-regulation of transport" EXACT []
synonym: "upregulation of transport" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006810 ! transport
relationship: positively_regulates GO:0006810 ! transport

[Term]
id: GO:0051051
name: negative regulation of transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "down regulation of transport" EXACT []
synonym: "down-regulation of transport" EXACT []
synonym: "downregulation of transport" EXACT []
synonym: "inhibition of transport" NARROW []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006810 ! transport
relationship: negatively_regulates GO:0006810 ! transport

[Term]
id: GO:0051052
name: regulation of DNA metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai]
subset: goslim_yeast
synonym: "regulation of DNA metabolism" EXACT []
is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
is_a: GO:0060255 ! regulation of macromolecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006259 ! DNA metabolic process
relationship: regulates GO:0006259 ! DNA metabolic process

[Term]
id: GO:0051053
name: negative regulation of DNA metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai]
synonym: "down regulation of DNA metabolic process" EXACT []
synonym: "down-regulation of DNA metabolic process" EXACT []
synonym: "downregulation of DNA metabolic process" EXACT []
synonym: "inhibition of DNA metabolic process" NARROW []
synonym: "negative regulation of DNA metabolism" EXACT []
is_a: GO:0010605 ! negative regulation of macromolecule metabolic process
is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process
is_a: GO:0051052 ! regulation of DNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006259 ! DNA metabolic process
relationship: negatively_regulates GO:0006259 ! DNA metabolic process

[Term]
id: GO:0051054
name: positive regulation of DNA metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai]
synonym: "activation of DNA metabolic process" NARROW []
synonym: "positive regulation of DNA metabolism" EXACT []
synonym: "stimulation of DNA metabolic process" NARROW []
synonym: "up regulation of DNA metabolic process" EXACT []
synonym: "up-regulation of DNA metabolic process" EXACT []
synonym: "upregulation of DNA metabolic process" EXACT []
is_a: GO:0010604 ! positive regulation of macromolecule metabolic process
is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process
is_a: GO:0051052 ! regulation of DNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006259 ! DNA metabolic process
relationship: positively_regulates GO:0006259 ! DNA metabolic process

[Term]
id: GO:0051055
name: negative regulation of lipid biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai]
synonym: "down regulation of lipid biosynthetic process" EXACT []
synonym: "down-regulation of lipid biosynthetic process" EXACT []
synonym: "downregulation of lipid biosynthetic process" EXACT []
synonym: "inhibition of lipid biosynthetic process" NARROW []
synonym: "negative regulation of lipid anabolism" EXACT []
synonym: "negative regulation of lipid biosynthesis" EXACT []
synonym: "negative regulation of lipid formation" EXACT []
synonym: "negative regulation of lipid synthesis" EXACT []
synonym: "negative regulation of lipogenesis" EXACT [GOC:sl]
is_a: GO:0009890 ! negative regulation of biosynthetic process
is_a: GO:0045833 ! negative regulation of lipid metabolic process
is_a: GO:0046890 ! regulation of lipid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008610 ! lipid biosynthetic process
relationship: negatively_regulates GO:0008610 ! lipid biosynthetic process

[Term]
id: GO:0051078
name: meiotic nuclear membrane disassembly
namespace: biological_process
def: "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs." [GOC:bf]
synonym: "meiotic nuclear envelope breakdown" RELATED []
synonym: "meiotic nuclear envelope catabolism" RELATED []
synonym: "meiotic nuclear envelope degradation" RELATED []
synonym: "meiotic nuclear envelope disassembly" RELATED []
is_a: GO:0051081 ! nuclear membrane disassembly
is_a: GO:1903046 ! meiotic cell cycle process
intersection_of: GO:0051081 ! nuclear membrane disassembly
intersection_of: part_of GO:0051321 ! meiotic cell cycle

[Term]
id: GO:0051080
name: meiosis II nuclear membrane disassembly
namespace: biological_process
def: "The controlled breakdown of the nuclear membranes during the second division of meiosis." [GOC:bf]
synonym: "meiosis II nuclear envelope breakdown" RELATED []
synonym: "meiosis II nuclear envelope catabolism" RELATED []
synonym: "meiosis II nuclear envelope degradation" RELATED []
synonym: "meiosis II nuclear envelope disassembly" RELATED []
is_a: GO:0051078 ! meiotic nuclear membrane disassembly
intersection_of: GO:0051081 ! nuclear membrane disassembly
intersection_of: part_of GO:0007135 ! meiosis II
relationship: part_of GO:0007135 ! meiosis II

[Term]
id: GO:0051081
name: nuclear membrane disassembly
namespace: biological_process
def: "The controlled breakdown of the nuclear membranes, for example during cellular division." [GOC:ai]
synonym: "nuclear envelope breakdown" RELATED []
synonym: "nuclear envelope catabolism" RELATED []
synonym: "nuclear envelope degradation" RELATED []
synonym: "nuclear envelope disassembly" RELATED []
is_a: GO:0030397 ! membrane disassembly
is_a: GO:0071763 ! nuclear membrane organization
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0031965 ! nuclear membrane
relationship: results_in_disassembly_of GO:0031965 ! nuclear membrane

[Term]
id: GO:0051093
name: negative regulation of developmental process
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai]
synonym: "down regulation of developmental process" EXACT []
synonym: "down-regulation of developmental process" EXACT []
synonym: "downregulation of developmental process" EXACT []
synonym: "inhibition of developmental process" NARROW []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032502 ! developmental process
relationship: negatively_regulates GO:0032502 ! developmental process

[Term]
id: GO:0051094
name: positive regulation of developmental process
namespace: biological_process
def: "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai]
synonym: "activation of developmental process" NARROW []
synonym: "stimulation of developmental process" NARROW []
synonym: "up regulation of developmental process" EXACT []
synonym: "up-regulation of developmental process" EXACT []
synonym: "upregulation of developmental process" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032502 ! developmental process
relationship: positively_regulates GO:0032502 ! developmental process

[Term]
id: GO:0051119
name: sugar transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides." [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
synonym: "sugar/polyol channel activity" NARROW []
xref: Reactome:R-HSA-428779 "GLUT7 and GLUT11 transport glucose and fructose"
xref: Reactome:R-HSA-8875902 "SLC45A3 transports Glc from extracellular region to cytosol"
xref: Reactome:R-HSA-8876319 "SLC50A1 transports Glc from cytosol to extracellular region"
is_a: GO:0015144 ! carbohydrate transmembrane transporter activity

[Term]
id: GO:0051128
name: regulation of cellular component organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai]
synonym: "regulation of cell organisation" RELATED [GOC:mah]
synonym: "regulation of cell organization" RELATED [GOC:mah]
synonym: "regulation of cellular component organisation" EXACT []
synonym: "regulation of cellular component organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016043 ! cellular component organization
relationship: regulates GO:0016043 ! cellular component organization

[Term]
id: GO:0051129
name: negative regulation of cellular component organization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai]
synonym: "down regulation of cell organization" EXACT []
synonym: "down-regulation of cell organization" EXACT []
synonym: "downregulation of cell organization" EXACT []
synonym: "inhibition of cell organization" NARROW []
synonym: "negative regulation of cell organisation" RELATED [GOC:mah]
synonym: "negative regulation of cellular component organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0016043 ! cellular component organization
relationship: negatively_regulates GO:0016043 ! cellular component organization

[Term]
id: GO:0051130
name: positive regulation of cellular component organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai]
synonym: "activation of cell organization" NARROW []
synonym: "positive regulation of cell organisation" EXACT []
synonym: "positive regulation of cellular component organization and biogenesis" RELATED [GOC:mah]
synonym: "stimulation of cell organization" NARROW []
synonym: "up regulation of cell organization" EXACT []
synonym: "up-regulation of cell organization" EXACT []
synonym: "upregulation of cell organization" EXACT []
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0016043 ! cellular component organization
relationship: positively_regulates GO:0016043 ! cellular component organization

[Term]
id: GO:0051145
name: smooth muscle cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary." [CL:0000192, GOC:ai]
synonym: "nonstriated muscle cell differentiation" EXACT []
is_a: GO:0042692 ! muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000192 ! smooth muscle cell
relationship: results_in_acquisition_of_features_of CL:0000192 ! smooth muscle cell

[Term]
id: GO:0051146
name: striated muscle cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle." [CL:0000737, GOC:ai]
synonym: "voluntary muscle cell differentiation" NARROW []
is_a: GO:0042692 ! muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000737 ! striated muscle cell
relationship: results_in_acquisition_of_features_of CL:0000737 ! striated muscle cell

[Term]
id: GO:0051147
name: regulation of muscle cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042692 ! muscle cell differentiation
relationship: regulates GO:0042692 ! muscle cell differentiation

[Term]
id: GO:0051148
name: negative regulation of muscle cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai]
synonym: "down regulation of muscle cell differentiation" EXACT []
synonym: "down-regulation of muscle cell differentiation" EXACT []
synonym: "downregulation of muscle cell differentiation" EXACT []
synonym: "inhibition of muscle cell differentiation" NARROW []
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0051147 ! regulation of muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042692 ! muscle cell differentiation
relationship: negatively_regulates GO:0042692 ! muscle cell differentiation

[Term]
id: GO:0051149
name: positive regulation of muscle cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai]
synonym: "activation of muscle cell differentiation" NARROW []
synonym: "stimulation of muscle cell differentiation" NARROW []
synonym: "up regulation of muscle cell differentiation" EXACT []
synonym: "up-regulation of muscle cell differentiation" EXACT []
synonym: "upregulation of muscle cell differentiation" EXACT []
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0051147 ! regulation of muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0042692 ! muscle cell differentiation
relationship: positively_regulates GO:0042692 ! muscle cell differentiation

[Term]
id: GO:0051150
name: regulation of smooth muscle cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai]
is_a: GO:0051147 ! regulation of muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051145 ! smooth muscle cell differentiation
relationship: regulates GO:0051145 ! smooth muscle cell differentiation

[Term]
id: GO:0051151
name: negative regulation of smooth muscle cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai]
synonym: "down regulation of smooth muscle cell differentiation" EXACT []
synonym: "down-regulation of smooth muscle cell differentiation" EXACT []
synonym: "downregulation of smooth muscle cell differentiation" EXACT []
synonym: "inhibition of smooth muscle cell differentiation" NARROW []
is_a: GO:0051148 ! negative regulation of muscle cell differentiation
is_a: GO:0051150 ! regulation of smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051145 ! smooth muscle cell differentiation
relationship: negatively_regulates GO:0051145 ! smooth muscle cell differentiation

[Term]
id: GO:0051152
name: positive regulation of smooth muscle cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai]
synonym: "activation of smooth muscle cell differentiation" NARROW []
synonym: "stimulation of smooth muscle cell differentiation" NARROW []
synonym: "up regulation of smooth muscle cell differentiation" EXACT []
synonym: "up-regulation of smooth muscle cell differentiation" EXACT []
synonym: "upregulation of smooth muscle cell differentiation" EXACT []
is_a: GO:0051149 ! positive regulation of muscle cell differentiation
is_a: GO:0051150 ! regulation of smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051145 ! smooth muscle cell differentiation
relationship: positively_regulates GO:0051145 ! smooth muscle cell differentiation

[Term]
id: GO:0051153
name: regulation of striated muscle cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai]
is_a: GO:0051147 ! regulation of muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051146 ! striated muscle cell differentiation
relationship: regulates GO:0051146 ! striated muscle cell differentiation

[Term]
id: GO:0051154
name: negative regulation of striated muscle cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai]
synonym: "down regulation of striated muscle cell differentiation" EXACT []
synonym: "down-regulation of striated muscle cell differentiation" EXACT []
synonym: "downregulation of striated muscle cell differentiation" EXACT []
synonym: "inhibition of striated muscle cell differentiation" NARROW []
is_a: GO:0051148 ! negative regulation of muscle cell differentiation
is_a: GO:0051153 ! regulation of striated muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051146 ! striated muscle cell differentiation
relationship: negatively_regulates GO:0051146 ! striated muscle cell differentiation

[Term]
id: GO:0051155
name: positive regulation of striated muscle cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai]
synonym: "activation of striated muscle cell differentiation" NARROW []
synonym: "stimulation of striated muscle cell differentiation" NARROW []
synonym: "up regulation of striated muscle cell differentiation" EXACT []
synonym: "up-regulation of striated muscle cell differentiation" EXACT []
synonym: "upregulation of striated muscle cell differentiation" EXACT []
is_a: GO:0051149 ! positive regulation of muscle cell differentiation
is_a: GO:0051153 ! regulation of striated muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051146 ! striated muscle cell differentiation
relationship: positively_regulates GO:0051146 ! striated muscle cell differentiation

[Term]
id: GO:0051169
name: nuclear transport
namespace: biological_process
def: "The directed movement of substances into, out of, or within the nucleus." [GOC:ai]
subset: goslim_yeast
synonym: "nucleus transport" EXACT []
xref: Wikipedia:Nuclear_transport
is_a: GO:0046907 ! intracellular transport
intersection_of: GO:0006810 ! transport
intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure
intersection_of: results_in_transport_to_from_or_in GO:0005634 ! nucleus
relationship: results_in_transport_to_from_or_in GO:0005634 ! nucleus

[Term]
id: GO:0051171
name: regulation of nitrogen compound metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb]
synonym: "regulation of nitrogen metabolic process" EXACT [GOC:tb]
synonym: "regulation of nitrogen metabolism" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006807 ! nitrogen compound metabolic process
relationship: regulates GO:0006807 ! nitrogen compound metabolic process

[Term]
id: GO:0051172
name: negative regulation of nitrogen compound metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb]
synonym: "down regulation of nitrogen metabolic process" EXACT []
synonym: "down-regulation of nitrogen metabolic process" EXACT []
synonym: "downregulation of nitrogen metabolic process" EXACT []
synonym: "inhibition of nitrogen metabolic process" NARROW []
synonym: "negative regulation of nitrogen metabolic process" EXACT [GOC:tb]
synonym: "negative regulation of nitrogen metabolism" EXACT []
is_a: GO:0009892 ! negative regulation of metabolic process
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006807 ! nitrogen compound metabolic process
relationship: negatively_regulates GO:0006807 ! nitrogen compound metabolic process

[Term]
id: GO:0051173
name: positive regulation of nitrogen compound metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb]
synonym: "activation of nitrogen metabolic process" NARROW []
synonym: "positive regulation of nitrogen metabolic process" EXACT [GOC:tb]
synonym: "positive regulation of nitrogen metabolism" EXACT []
synonym: "stimulation of nitrogen metabolic process" NARROW []
synonym: "up regulation of nitrogen metabolic process" EXACT []
synonym: "up-regulation of nitrogen metabolic process" EXACT []
synonym: "upregulation of nitrogen metabolic process" EXACT []
is_a: GO:0009893 ! positive regulation of metabolic process
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006807 ! nitrogen compound metabolic process
relationship: positively_regulates GO:0006807 ! nitrogen compound metabolic process

[Term]
id: GO:0051174
name: regulation of phosphorus metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:ai]
synonym: "regulation of phosphorus metabolism" EXACT []
is_a: GO:0031323 ! regulation of cellular metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006793 ! phosphorus metabolic process
relationship: regulates GO:0006793 ! phosphorus metabolic process

[Term]
id: GO:0051175
name: negative regulation of sulfur metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai]
synonym: "down regulation of sulfur metabolic process" EXACT []
synonym: "down-regulation of sulfur metabolic process" EXACT []
synonym: "downregulation of sulfur metabolic process" EXACT []
synonym: "inhibition of sulfur metabolic process" NARROW []
synonym: "negative regulation of sulfur metabolism" EXACT []
synonym: "negative regulation of sulphur metabolic process" EXACT []
synonym: "negative regulation of sulphur metabolism" EXACT []
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006790 ! sulfur compound metabolic process
relationship: negatively_regulates GO:0006790 ! sulfur compound metabolic process

[Term]
id: GO:0051176
name: positive regulation of sulfur metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai]
synonym: "activation of sulfur metabolic process" NARROW []
synonym: "positive regulation of sulfur metabolism" EXACT []
synonym: "positive regulation of sulphur metabolic process" EXACT []
synonym: "positive regulation of sulphur metabolism" EXACT []
synonym: "stimulation of sulfur metabolic process" NARROW []
synonym: "up regulation of sulfur metabolic process" EXACT []
synonym: "up-regulation of sulfur metabolic process" EXACT []
synonym: "upregulation of sulfur metabolic process" EXACT []
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0042762 ! regulation of sulfur metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006790 ! sulfur compound metabolic process
relationship: positively_regulates GO:0006790 ! sulfur compound metabolic process

[Term]
id: GO:0051179
name: localization
namespace: biological_process
alt_id: GO:1902578
def: "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." [GOC:ai, GOC:dos]
subset: goslim_pir
synonym: "establishment and maintenance of cellular component location" NARROW []
synonym: "establishment and maintenance of localization" EXACT []
synonym: "establishment and maintenance of position" EXACT []
synonym: "establishment and maintenance of substance location" NARROW []
synonym: "establishment and maintenance of substrate location" NARROW []
synonym: "localisation" EXACT [GOC:mah]
synonym: "single organism localization" RELATED [GOC:TermGenie]
synonym: "single-organism localization" RELATED []
is_a: GO:0008150 ! biological process
created_by: jl
creation_date: 2013-12-18T13:51:04Z

[Term]
id: GO:0051216
name: cartilage development
namespace: biological_process
def: "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:cjm, PMID:23251424]
synonym: "cartilage biogenesis" EXACT []
synonym: "cartilage biosynthesis" EXACT []
synonym: "cartilage element development" EXACT []
synonym: "cartilage formation" EXACT []
synonym: "cartilage organ development" EXACT []
synonym: "chondrogenesis" EXACT []
xref: Wikipedia:Chondrogenesis
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0007844 ! cartilage element
relationship: part_of GO:0001501 ! skeletal system development
relationship: part_of GO:0061448 ! connective tissue development
relationship: results_in_development_of UBERON:0007844 ! cartilage element

[Term]
id: GO:0051222
name: positive regulation of protein transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "activation of protein transport" NARROW []
synonym: "stimulation of protein transport" NARROW []
synonym: "up regulation of protein transport" EXACT []
synonym: "up-regulation of protein transport" EXACT []
synonym: "upregulation of protein transport" EXACT []
is_a: GO:0051050 ! positive regulation of transport
is_a: GO:0051223 ! regulation of protein transport
is_a: GO:1903829 ! positive regulation of protein localization
is_a: GO:1904951 ! positive regulation of establishment of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0015031 ! protein transport
relationship: positively_regulates GO:0015031 ! protein transport

[Term]
id: GO:0051223
name: regulation of protein transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
is_a: GO:0051049 ! regulation of transport
is_a: GO:0070201 ! regulation of establishment of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0015031 ! protein transport
relationship: regulates GO:0015031 ! protein transport

[Term]
id: GO:0051224
name: negative regulation of protein transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "down regulation of protein transport" EXACT []
synonym: "down-regulation of protein transport" EXACT []
synonym: "downregulation of protein transport" EXACT []
synonym: "inhibition of protein transport" NARROW []
is_a: GO:0051051 ! negative regulation of transport
is_a: GO:0051223 ! regulation of protein transport
is_a: GO:1903828 ! negative regulation of protein localization
is_a: GO:1904950 ! negative regulation of establishment of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0015031 ! protein transport
relationship: negatively_regulates GO:0015031 ! protein transport

[Term]
id: GO:0051234
name: establishment of localization
namespace: biological_process
def: "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos]
subset: gocheck_do_not_annotate
subset: goslim_agr
subset: goslim_flybase_ribbon
subset: goslim_mouse
subset: goslim_pir
synonym: "establishment of localisation" EXACT [GOC:mah]
is_a: GO:0051179 ! localization
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI

[Term]
id: GO:0051236
name: establishment of RNA localization
namespace: biological_process
def: "The directed movement of RNA to a specific location." [GOC:ai]
synonym: "establishment of RNA localisation" EXACT [GOC:mah]
synonym: "RNA positioning" EXACT []
synonym: "RNA recruitment" EXACT []
is_a: GO:0051234 ! establishment of localization
relationship: part_of GO:0006403 ! RNA localization

[Term]
id: GO:0051239
name: regulation of multicellular organismal process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai, GOC:dph, GOC:tb]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032501 ! multicellular organismal process
relationship: regulates GO:0032501 ! multicellular organismal process

[Term]
id: GO:0051240
name: positive regulation of multicellular organismal process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai]
synonym: "activation of multicellular organismal process" NARROW []
synonym: "stimulation of multicellular organismal process" NARROW []
synonym: "up regulation of multicellular organismal process" EXACT []
synonym: "up-regulation of multicellular organismal process" EXACT []
synonym: "upregulation of multicellular organismal process" EXACT []
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032501 ! multicellular organismal process
relationship: positively_regulates GO:0032501 ! multicellular organismal process

[Term]
id: GO:0051241
name: negative regulation of multicellular organismal process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai]
synonym: "down regulation of multicellular organismal process" EXACT []
synonym: "down-regulation of multicellular organismal process" EXACT []
synonym: "downregulation of multicellular organismal process" EXACT []
synonym: "inhibition of multicellular organismal process" NARROW []
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032501 ! multicellular organismal process
relationship: negatively_regulates GO:0032501 ! multicellular organismal process

[Term]
id: GO:0051246
name: regulation of protein metabolic process
namespace: biological_process
alt_id: GO:0032268
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai]
synonym: "regulation of cellular protein metabolic process" RELATED []
synonym: "regulation of cellular protein metabolism" RELATED []
synonym: "regulation of protein metabolism" EXACT []
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
is_a: GO:0080090 ! regulation of primary metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0019538 ! protein metabolic process
relationship: regulates GO:0019538 ! protein metabolic process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI

[Term]
id: GO:0051247
name: positive regulation of protein metabolic process
namespace: biological_process
alt_id: GO:0032270
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai]
synonym: "activation of cellular protein metabolic process" NARROW []
synonym: "activation of protein metabolic process" NARROW []
synonym: "positive regulation of cellular protein metabolic process" EXACT []
synonym: "positive regulation of cellular protein metabolism" EXACT []
synonym: "positive regulation of protein metabolism" EXACT []
synonym: "stimulation of cellular protein metabolic process" NARROW []
synonym: "stimulation of protein metabolic process" NARROW []
synonym: "up regulation of cellular protein metabolic process" EXACT []
synonym: "up regulation of protein metabolic process" EXACT []
synonym: "up-regulation of cellular protein metabolic process" EXACT []
synonym: "up-regulation of protein metabolic process" EXACT []
synonym: "upregulation of cellular protein metabolic process" EXACT []
synonym: "upregulation of protein metabolic process" EXACT []
is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process
is_a: GO:0051246 ! regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0019538 ! protein metabolic process
relationship: positively_regulates GO:0019538 ! protein metabolic process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI

[Term]
id: GO:0051248
name: negative regulation of protein metabolic process
namespace: biological_process
alt_id: GO:0032269
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein." [GOC:ai]
synonym: "down regulation of cellular protein metabolic process" EXACT []
synonym: "down regulation of protein metabolic process" EXACT []
synonym: "down-regulation of cellular protein metabolic process" EXACT []
synonym: "down-regulation of protein metabolic process" EXACT []
synonym: "downregulation of cellular protein metabolic process" EXACT []
synonym: "downregulation of protein metabolic process" EXACT []
synonym: "inhibition of cellular protein metabolic process" NARROW []
synonym: "inhibition of protein metabolic process" NARROW []
synonym: "negative regulation of cellular protein metabolic process" EXACT []
synonym: "negative regulation of cellular protein metabolism" EXACT []
synonym: "negative regulation of protein metabolism" EXACT []
is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process
is_a: GO:0051246 ! regulation of protein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0019538 ! protein metabolic process
relationship: negatively_regulates GO:0019538 ! protein metabolic process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI

[Term]
id: GO:0051249
name: regulation of lymphocyte activation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of lymphocyte activation." [GOC:ai]
is_a: GO:0002694 ! regulation of leukocyte activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0046649 ! lymphocyte activation
relationship: regulates GO:0046649 ! lymphocyte activation

[Term]
id: GO:0051250
name: negative regulation of lymphocyte activation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation." [GOC:ai]
synonym: "down regulation of lymphocyte activation" EXACT []
synonym: "down-regulation of lymphocyte activation" EXACT []
synonym: "downregulation of lymphocyte activation" EXACT []
synonym: "inhibition of lymphocyte activation" NARROW []
is_a: GO:0002695 ! negative regulation of leukocyte activation
is_a: GO:0051249 ! regulation of lymphocyte activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0046649 ! lymphocyte activation
relationship: negatively_regulates GO:0046649 ! lymphocyte activation

[Term]
id: GO:0051251
name: positive regulation of lymphocyte activation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." [GOC:ai]
synonym: "activation of lymphocyte activation" NARROW []
synonym: "stimulation of lymphocyte activation" NARROW []
synonym: "up regulation of lymphocyte activation" EXACT []
synonym: "up-regulation of lymphocyte activation" EXACT []
synonym: "upregulation of lymphocyte activation" EXACT []
is_a: GO:0002696 ! positive regulation of leukocyte activation
is_a: GO:0051249 ! regulation of lymphocyte activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0046649 ! lymphocyte activation
relationship: positively_regulates GO:0046649 ! lymphocyte activation

[Term]
id: GO:0051252
name: regulation of RNA metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai]
synonym: "regulation of RNA metabolism" EXACT []
is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
is_a: GO:0060255 ! regulation of macromolecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016070 ! RNA metabolic process
relationship: regulates GO:0016070 ! RNA metabolic process

[Term]
id: GO:0051253
name: negative regulation of RNA metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai]
synonym: "down regulation of RNA metabolic process" EXACT []
synonym: "down-regulation of RNA metabolic process" EXACT []
synonym: "downregulation of RNA metabolic process" EXACT []
synonym: "inhibition of RNA metabolic process" NARROW []
synonym: "negative regulation of RNA metabolism" EXACT []
is_a: GO:0010605 ! negative regulation of macromolecule metabolic process
is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process
is_a: GO:0051252 ! regulation of RNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0016070 ! RNA metabolic process
relationship: negatively_regulates GO:0016070 ! RNA metabolic process

[Term]
id: GO:0051254
name: positive regulation of RNA metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai]
synonym: "activation of RNA metabolic process" NARROW []
synonym: "positive regulation of RNA metabolism" EXACT []
synonym: "stimulation of RNA metabolic process" NARROW []
synonym: "up regulation of RNA metabolic process" EXACT []
synonym: "up-regulation of RNA metabolic process" EXACT []
synonym: "upregulation of RNA metabolic process" EXACT []
is_a: GO:0010604 ! positive regulation of macromolecule metabolic process
is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process
is_a: GO:0051252 ! regulation of RNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0016070 ! RNA metabolic process
relationship: positively_regulates GO:0016070 ! RNA metabolic process

[Term]
id: GO:0051258
name: protein polymerization
namespace: biological_process
def: "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." [GOC:ai]
subset: goslim_pir
synonym: "protein polymer biosynthesis" EXACT []
synonym: "protein polymer biosynthetic process" EXACT []
synonym: "protein polymer formation" EXACT []
is_a: GO:0065003 ! protein-containing complex assembly

[Term]
id: GO:0051261
name: protein depolymerization
namespace: biological_process
def: "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein." [GOC:ai]
subset: goslim_pir
synonym: "protein polymer breakdown" EXACT []
synonym: "protein polymer catabolic process" EXACT []
synonym: "protein polymer catabolism" EXACT []
synonym: "protein polymer degradation" EXACT []
is_a: GO:0032984 ! protein-containing complex disassembly

[Term]
id: GO:0051276
name: chromosome organization
namespace: biological_process
alt_id: GO:0006323
alt_id: GO:0007001
alt_id: GO:0051277
def: "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome." [GOC:ai, GOC:dph, GOC:jl, GOC:mah]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_pir
synonym: "chromosome organisation" EXACT []
synonym: "chromosome organization and biogenesis" RELATED [GOC:mah]
synonym: "DNA condensation" EXACT []
synonym: "DNA packaging" NARROW []
synonym: "maintenance of genome integrity" RELATED []
synonym: "nuclear genome maintenance" RELATED []
is_a: GO:0006996 ! organelle organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005694 ! chromosome
relationship: results_in_organization_of GO:0005694 ! chromosome
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22811" xsd:anyURI
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/4585" xsd:anyURI

[Term]
id: GO:0051301
name: cell division
namespace: biological_process
def: "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." [GOC:di, GOC:go_curators, GOC:pr]
comment: Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division.
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_pir
xref: Wikipedia:Cell_division
is_a: GO:0009987 ! cellular process

[Term]
id: GO:0051302
name: regulation of cell division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." [GOC:go_curators]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051301 ! cell division
relationship: regulates GO:0051301 ! cell division

[Term]
id: GO:0051303
name: establishment of chromosome localization
namespace: biological_process
def: "The directed movement of a chromosome to a specific location." [GOC:ai]
synonym: "chromosome positioning" EXACT []
synonym: "establishment of chromosome localisation" EXACT [GOC:mah]
is_a: GO:0050000 ! chromosome localization
is_a: GO:0051649 ! establishment of localization in cell
is_a: GO:0051656 ! establishment of organelle localization
intersection_of: GO:0051234 ! establishment of localization
intersection_of: has_primary_input GO:0005694 ! chromosome

[Term]
id: GO:0051321
name: meiotic cell cycle
namespace: biological_process
alt_id: GO:0007126
def: "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions." [GOC:ai]
comment: Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.
subset: goslim_drosophila
subset: goslim_yeast
synonym: "meiosis" RELATED []
xref: Wikipedia:Meiosis
is_a: GO:0007049 ! cell cycle
is_a: GO:0022414 ! reproductive process
intersection_of: GO:0007049 ! cell cycle
intersection_of: has_part GO:0140013 ! meiotic nuclear division
relationship: has_part GO:0140013 ! meiotic nuclear division
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
relationship: part_of GO:0019953 ! sexual reproduction
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24599" xsd:anyURI

[Term]
id: GO:0051336
name: regulation of hydrolase activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [GOC:ai]
subset: gocheck_do_not_annotate
synonym: "hydrolase regulator" EXACT []
is_a: GO:0050790 ! regulation of catalytic activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016787 ! hydrolase activity
relationship: regulates GO:0016787 ! hydrolase activity

[Term]
id: GO:0051338
name: regulation of transferase activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [GOC:ai]
comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
subset: gocheck_do_not_annotate
subset: gocheck_do_not_manually_annotate
synonym: "transferase regulator" EXACT []
is_a: GO:0050790 ! regulation of catalytic activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016740 ! transferase activity
relationship: regulates GO:0016740 ! transferase activity

[Term]
id: GO:0051345
name: positive regulation of hydrolase activity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai]
subset: gocheck_do_not_annotate
synonym: "activation of hydrolase activity" NARROW []
synonym: "hydrolase activator" EXACT []
synonym: "stimulation of hydrolase activity" NARROW []
synonym: "up regulation of hydrolase activity" EXACT []
synonym: "up-regulation of hydrolase activity" EXACT []
synonym: "upregulation of hydrolase activity" EXACT []
is_a: GO:0043085 ! positive regulation of catalytic activity
is_a: GO:0051336 ! regulation of hydrolase activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0016787 ! hydrolase activity
relationship: positively_regulates GO:0016787 ! hydrolase activity

[Term]
id: GO:0051346
name: negative regulation of hydrolase activity
namespace: biological_process
def: "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai]
subset: gocheck_do_not_annotate
synonym: "down regulation of hydrolase activity" EXACT []
synonym: "down-regulation of hydrolase activity" EXACT []
synonym: "downregulation of hydrolase activity" EXACT []
synonym: "hydrolase inhibitor" EXACT []
synonym: "inhibition of hydrolase activity" NARROW []
is_a: GO:0043086 ! negative regulation of catalytic activity
is_a: GO:0051336 ! regulation of hydrolase activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0016787 ! hydrolase activity
relationship: negatively_regulates GO:0016787 ! hydrolase activity

[Term]
id: GO:0051347
name: positive regulation of transferase activity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai]
comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
subset: gocheck_do_not_annotate
subset: gocheck_do_not_manually_annotate
synonym: "activation of transferase activity" NARROW []
synonym: "stimulation of transferase activity" NARROW []
synonym: "transferase activator" EXACT []
synonym: "up regulation of transferase activity" EXACT []
synonym: "up-regulation of transferase activity" EXACT []
synonym: "upregulation of transferase activity" EXACT []
is_a: GO:0043085 ! positive regulation of catalytic activity
is_a: GO:0051338 ! regulation of transferase activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0016740 ! transferase activity
relationship: positively_regulates GO:0016740 ! transferase activity

[Term]
id: GO:0051348
name: negative regulation of transferase activity
namespace: biological_process
def: "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai]
comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
subset: gocheck_do_not_annotate
subset: gocheck_do_not_manually_annotate
synonym: "down regulation of transferase activity" EXACT []
synonym: "down-regulation of transferase activity" EXACT []
synonym: "downregulation of transferase activity" EXACT []
synonym: "inhibition of transferase activity" NARROW []
synonym: "transferase inhibitor" EXACT []
is_a: GO:0043086 ! negative regulation of catalytic activity
is_a: GO:0051338 ! regulation of transferase activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0016740 ! transferase activity
relationship: negatively_regulates GO:0016740 ! transferase activity

[Term]
id: GO:0051402
name: neuron apoptotic process
namespace: biological_process
def: "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [CL:0000540, GOC:mtg_apoptosis]
synonym: "apoptosis of neuronal cells" EXACT []
synonym: "apoptosis of neurons" EXACT []
synonym: "neuron apoptosis" NARROW []
synonym: "neuron programmed cell death by apoptosis" EXACT []
synonym: "neuronal cell apoptosis" EXACT []
synonym: "neuronal cell programmed cell death by apoptosis" EXACT []
synonym: "programmed cell death of neuronal cells by apoptosis" EXACT []
synonym: "programmed cell death of neurons by apoptosis" EXACT []
synonym: "programmed cell death, neuronal cells" EXACT []
synonym: "programmed cell death, neurons" EXACT []
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000540 ! neuron
relationship: occurs_in CL:0000540 ! neuron

[Term]
id: GO:0051410
name: detoxification of nitrogen compound
namespace: biological_process
def: "Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances." [GOC:ai]
synonym: "detoxification of nitrogenous compound" EXACT []
synonym: "nitric oxide (NO) detoxification" NARROW []
is_a: GO:0098754 ! detoxification
intersection_of: GO:0098754 ! detoxification
intersection_of: has_primary_input CHEBI:51143 ! nitrogen molecular entity
relationship: has_primary_input CHEBI:51143 ! nitrogen molecular entity
relationship: part_of GO:1901698 ! response to nitrogen compound

[Term]
id: GO:0051445
name: regulation of meiotic cell cycle
namespace: biological_process
def: "Any process that modulates the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb]
synonym: "meiotic cell cycle modulation" EXACT []
synonym: "meiotic cell cycle regulation" EXACT []
synonym: "meiotic cell cycle regulator" RELATED []
synonym: "modulation of meiotic cell cycle progression" EXACT []
synonym: "regulation of meiotic cell cycle progression" EXACT []
synonym: "regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb]
is_a: GO:0051726 ! regulation of cell cycle
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051321 ! meiotic cell cycle
relationship: regulates GO:0051321 ! meiotic cell cycle

[Term]
id: GO:0051446
name: positive regulation of meiotic cell cycle
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb]
synonym: "activation of progression through meiotic cell cycle" NARROW []
synonym: "positive regulation of meiotic cell cycle progression" EXACT []
synonym: "positive regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb]
synonym: "stimulation of progression through meiotic cell cycle" NARROW []
synonym: "up regulation of progression through meiotic cell cycle" EXACT []
synonym: "up-regulation of progression through meiotic cell cycle" EXACT []
synonym: "upregulation of progression through meiotic cell cycle" EXACT []
is_a: GO:0045787 ! positive regulation of cell cycle
is_a: GO:0051445 ! regulation of meiotic cell cycle
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051321 ! meiotic cell cycle
relationship: positively_regulates GO:0051321 ! meiotic cell cycle

[Term]
id: GO:0051447
name: negative regulation of meiotic cell cycle
namespace: biological_process
def: "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb]
synonym: "down regulation of progression through meiotic cell cycle" EXACT []
synonym: "down-regulation of progression through meiotic cell cycle" EXACT []
synonym: "downregulation of progression through meiotic cell cycle" EXACT []
synonym: "inhibition of progression through meiotic cell cycle" NARROW []
synonym: "negative regulation of meiotic cell cycle progression" EXACT []
synonym: "negative regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb]
is_a: GO:0045786 ! negative regulation of cell cycle
is_a: GO:0051445 ! regulation of meiotic cell cycle
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051321 ! meiotic cell cycle
relationship: negatively_regulates GO:0051321 ! meiotic cell cycle

[Term]
id: GO:0051450
name: myoblast proliferation
namespace: biological_process
def: "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000056 ! myoblast
relationship: acts_on_population_of CL:0000056 ! myoblast

[Term]
id: GO:0051451
name: myoblast migration
namespace: biological_process
def: "The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle]
is_a: GO:0014812 ! muscle cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000056 ! myoblast
relationship: results_in_movement_of CL:0000056 ! myoblast

[Term]
id: GO:0051469
name: vesicle fusion with vacuole
namespace: biological_process
alt_id: GO:0042146
def: "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole." [GOC:ai]
synonym: "heterotypic vacuole fusion (non-autophagic)" RELATED []
synonym: "heterotypic vacuole fusion, non-autophagic" RELATED []
is_a: GO:0006906 ! vesicle fusion
is_a: GO:0097576 ! vacuole fusion
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_fusion_of GO:0005773 ! vacuole
intersection_of: results_in_fusion_of GO:0031982 ! vesicle
relationship: results_in_fusion_of GO:0031982 ! vesicle

[Term]
id: GO:0051493
name: regulation of cytoskeleton organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai]
synonym: "regulation of cytoskeleton organisation" EXACT [GOC:mah]
synonym: "regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0033043 ! regulation of organelle organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007010 ! cytoskeleton organization
relationship: regulates GO:0007010 ! cytoskeleton organization

[Term]
id: GO:0051494
name: negative regulation of cytoskeleton organization
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai]
synonym: "down regulation of cytoskeleton organization" EXACT []
synonym: "down-regulation of cytoskeleton organization" EXACT []
synonym: "downregulation of cytoskeleton organization" EXACT []
synonym: "inhibition of cytoskeleton organization" NARROW []
synonym: "negative regulation of cytoskeleton organisation" EXACT [GOC:mah]
synonym: "negative regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0010639 ! negative regulation of organelle organization
is_a: GO:0051493 ! regulation of cytoskeleton organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007010 ! cytoskeleton organization
relationship: negatively_regulates GO:0007010 ! cytoskeleton organization

[Term]
id: GO:0051495
name: positive regulation of cytoskeleton organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai]
synonym: "activation of cytoskeleton organization" NARROW []
synonym: "positive regulation of cytoskeleton organisation" EXACT [GOC:mah]
synonym: "positive regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah]
synonym: "stimulation of cytoskeleton organization" NARROW []
synonym: "up regulation of cytoskeleton organization" EXACT []
synonym: "up-regulation of cytoskeleton organization" EXACT []
synonym: "upregulation of cytoskeleton organization" EXACT []
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:0051493 ! regulation of cytoskeleton organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007010 ! cytoskeleton organization
relationship: positively_regulates GO:0007010 ! cytoskeleton organization

[Term]
id: GO:0051588
name: regulation of neurotransmitter transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006836 ! neurotransmitter transport
relationship: regulates GO:0006836 ! neurotransmitter transport

[Term]
id: GO:0051589
name: negative regulation of neurotransmitter transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "down regulation of neurotransmitter transport" EXACT []
synonym: "down-regulation of neurotransmitter transport" EXACT []
synonym: "downregulation of neurotransmitter transport" EXACT []
synonym: "inhibition of neurotransmitter transport" NARROW []
is_a: GO:0051051 ! negative regulation of transport
is_a: GO:0051588 ! regulation of neurotransmitter transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006836 ! neurotransmitter transport
relationship: negatively_regulates GO:0006836 ! neurotransmitter transport

[Term]
id: GO:0051590
name: positive regulation of neurotransmitter transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "activation of neurotransmitter transport" NARROW []
synonym: "stimulation of neurotransmitter transport" NARROW []
synonym: "up regulation of neurotransmitter transport" EXACT []
synonym: "up-regulation of neurotransmitter transport" EXACT []
synonym: "upregulation of neurotransmitter transport" EXACT []
is_a: GO:0051050 ! positive regulation of transport
is_a: GO:0051588 ! regulation of neurotransmitter transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006836 ! neurotransmitter transport
relationship: positively_regulates GO:0006836 ! neurotransmitter transport

[Term]
id: GO:0051602
name: response to electrical stimulus
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus." [GOC:ai]
synonym: "response to electricity" RELATED []
is_a: GO:0009628 ! response to abiotic stimulus

[Term]
id: GO:0051606
name: detection of stimulus
namespace: biological_process
def: "The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal." [GOC:add, GOC:ai, GOC:dph, GOC:mah]
subset: goslim_pir
synonym: "perception of stimulus" RELATED []
synonym: "stimulus detection" EXACT []
synonym: "stimulus sensing" RELATED []
is_a: GO:0050896 ! response to stimulus

[Term]
id: GO:0051620
name: norepinephrine uptake
namespace: biological_process
def: "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai]
synonym: "levarterenol reuptake" EXACT []
synonym: "levarterenol uptake" EXACT []
synonym: "noradrenaline reuptake" EXACT []
synonym: "noradrenaline uptake" EXACT []
synonym: "norepinephrine import" EXACT [GOC:dph, GOC:tb]
synonym: "norepinephrine reuptake" EXACT []
is_a: GO:0015874 ! norepinephrine transport
is_a: GO:0090493 ! catecholamine uptake
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+)
intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure
intersection_of: has_target_start_location GO:0005576 ! extracellular region

[Term]
id: GO:0051621
name: regulation of norepinephrine uptake
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell." [GOC:ai]
synonym: "regulation of levarterenol uptake" EXACT []
synonym: "regulation of noradrenaline uptake" EXACT []
synonym: "regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb]
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051620 ! norepinephrine uptake
relationship: regulates GO:0051620 ! norepinephrine uptake

[Term]
id: GO:0051622
name: negative regulation of norepinephrine uptake
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai]
synonym: "down regulation of norepinephrine uptake" EXACT []
synonym: "down-regulation of norepinephrine uptake" EXACT []
synonym: "downregulation of norepinephrine uptake" EXACT []
synonym: "negative regulation of levarterenol uptake" EXACT []
synonym: "negative regulation of noradrenaline uptake" EXACT []
synonym: "negative regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb]
is_a: GO:0051051 ! negative regulation of transport
is_a: GO:0051621 ! regulation of norepinephrine uptake
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051620 ! norepinephrine uptake
relationship: negatively_regulates GO:0051620 ! norepinephrine uptake

[Term]
id: GO:0051623
name: positive regulation of norepinephrine uptake
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai]
synonym: "activation of norepinephrine uptake" NARROW []
synonym: "positive regulation of levarterenol uptake" EXACT []
synonym: "positive regulation of noradrenaline uptake" EXACT []
synonym: "positive regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb]
synonym: "stimulation of norepinephrine uptake" NARROW []
synonym: "up regulation of norepinephrine uptake" EXACT []
synonym: "up-regulation of norepinephrine uptake" EXACT []
synonym: "upregulation of norepinephrine uptake" EXACT []
is_a: GO:0051050 ! positive regulation of transport
is_a: GO:0051621 ! regulation of norepinephrine uptake
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051620 ! norepinephrine uptake
relationship: positively_regulates GO:0051620 ! norepinephrine uptake

[Term]
id: GO:0051630
name: acetylcholine uptake
namespace: biological_process
def: "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:ai]
synonym: "acetylcholine import" EXACT [GOC:dph, GOC:tb]
is_a: GO:0015870 ! acetylcholine transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:15355 ! acetylcholine
intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure
intersection_of: has_target_start_location GO:0005576 ! extracellular region
relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure
relationship: has_target_start_location GO:0005576 ! extracellular region

[Term]
id: GO:0051631
name: regulation of acetylcholine uptake
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell." [GOC:ai]
synonym: "regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb]
is_a: GO:0051952 ! regulation of amine transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051630 ! acetylcholine uptake
relationship: regulates GO:0051630 ! acetylcholine uptake

[Term]
id: GO:0051632
name: negative regulation of acetylcholine uptake
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai]
synonym: "down regulation of acetylcholine uptake" EXACT []
synonym: "down-regulation of acetylcholine uptake" EXACT []
synonym: "downregulation of acetylcholine uptake" EXACT []
synonym: "negative regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb]
is_a: GO:0051631 ! regulation of acetylcholine uptake
is_a: GO:0051953 ! negative regulation of amine transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051630 ! acetylcholine uptake
relationship: negatively_regulates GO:0051630 ! acetylcholine uptake

[Term]
id: GO:0051633
name: positive regulation of acetylcholine uptake
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai]
synonym: "activation of acetylcholine uptake" NARROW []
synonym: "positive regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb]
synonym: "stimulation of acetylcholine uptake" NARROW []
synonym: "up regulation of acetylcholine uptake" EXACT []
synonym: "up-regulation of acetylcholine uptake" EXACT []
synonym: "upregulation of acetylcholine uptake" EXACT []
is_a: GO:0051631 ! regulation of acetylcholine uptake
is_a: GO:0051954 ! positive regulation of amine transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051630 ! acetylcholine uptake
relationship: positively_regulates GO:0051630 ! acetylcholine uptake

[Term]
id: GO:0051640
name: organelle localization
namespace: biological_process
def: "Any process in which an organelle is transported to, and/or maintained in, a specific location." [GOC:ai]
subset: goslim_pir
synonym: "establishment and maintenance of organelle localization" EXACT []
synonym: "organelle localisation" EXACT [GOC:mah]
is_a: GO:0051179 ! localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0043226 ! organelle
relationship: has_primary_input GO:0043226 ! organelle
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI

[Term]
id: GO:0051641
name: cellular localization
namespace: biological_process
alt_id: GO:1902580
def: "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." [GOC:tb, GOC:vw]
subset: goslim_pir
synonym: "cellular localisation" EXACT [GOC:mah]
synonym: "establishment and maintenance of cellular localization" EXACT []
synonym: "establishment and maintenance of localization in cell or cell membrane" EXACT []
synonym: "intracellular localization" NARROW []
synonym: "localization within cell" NARROW []
synonym: "single organism cellular localization" EXACT [GOC:TermGenie]
synonym: "single-organism cellular localization" RELATED []
is_a: GO:0009987 ! cellular process
is_a: GO:0051179 ! localization
created_by: jl
creation_date: 2013-12-18T14:04:32Z

[Term]
id: GO:0051645
name: Golgi localization
namespace: biological_process
def: "Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell." [GOC:ai]
synonym: "establishment and maintenance of Golgi localization" EXACT []
synonym: "Golgi apparatus localization" EXACT []
synonym: "Golgi body localization" EXACT []
synonym: "Golgi localisation" EXACT [GOC:mah]
is_a: GO:0051640 ! organelle localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0005794 ! Golgi apparatus
relationship: has_primary_input GO:0005794 ! Golgi apparatus

[Term]
id: GO:0051647
name: nucleus localization
namespace: biological_process
def: "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell." [GOC:ai]
synonym: "cell nucleus localization" EXACT []
synonym: "establishment and maintenance of nucleus localization" EXACT []
synonym: "localization of nucleus" EXACT []
synonym: "nucleus localisation" EXACT [GOC:mah]
is_a: GO:0051640 ! organelle localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0005634 ! nucleus
relationship: has_primary_input GO:0005634 ! nucleus

[Term]
id: GO:0051648
name: vesicle localization
namespace: biological_process
def: "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location." [GOC:ai]
synonym: "cytoplasmic vesicle localization" EXACT []
synonym: "establishment and maintenance of vesicle localization" EXACT []
synonym: "vesicle localisation" EXACT [GOC:mah]
is_a: GO:0051640 ! organelle localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0031982 ! vesicle
relationship: has_primary_input GO:0031982 ! vesicle

[Term]
id: GO:0051649
name: establishment of localization in cell
namespace: biological_process
def: "Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos, GOC:dph, GOC:tb]
synonym: "establishment of cellular localization" RELATED [GOC:dph, GOC:tb]
synonym: "establishment of intracellular localization" NARROW []
synonym: "establishment of localisation in cell" EXACT [GOC:mah]
synonym: "establishment of localization within cell" NARROW []
synonym: "positioning within cell" NARROW []
is_a: GO:0051234 ! establishment of localization
intersection_of: GO:0051234 ! establishment of localization
intersection_of: occurs_in CL:0000000 ! cell
relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms
relationship: occurs_in CL:0000000 ! cell
relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms
relationship: part_of GO:0051641 ! cellular localization

[Term]
id: GO:0051650
name: establishment of vesicle localization
namespace: biological_process
def: "The directed movement of a vesicle to a specific location." [GOC:ai]
synonym: "establishment of vesicle localisation" EXACT [GOC:mah]
is_a: GO:0051648 ! vesicle localization
is_a: GO:0051649 ! establishment of localization in cell
is_a: GO:0051656 ! establishment of organelle localization
intersection_of: GO:0051234 ! establishment of localization
intersection_of: has_primary_input GO:0031982 ! vesicle

[Term]
id: GO:0051656
name: establishment of organelle localization
namespace: biological_process
def: "The directed movement of an organelle to a specific location." [GOC:ai]
synonym: "establishment of organelle localisation" EXACT [GOC:mah]
is_a: GO:0051234 ! establishment of localization
is_a: GO:0051640 ! organelle localization
intersection_of: GO:0051234 ! establishment of localization
intersection_of: has_primary_input GO:0043226 ! organelle

[Term]
id: GO:0051668
name: localization within membrane
namespace: biological_process
def: "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane." [GOC:ai]
synonym: "establishment and maintenance of localization in membrane" EXACT []
synonym: "establishment and maintenance of position in membrane" EXACT []
synonym: "localisation within membrane" EXACT [GOC:mah]
synonym: "localization to membrane" EXACT []
synonym: "positioning within membrane" NARROW []
is_a: GO:0051641 ! cellular localization
intersection_of: GO:0051179 ! localization
intersection_of: has_target_end_location GO:0016020 ! membrane
relationship: has_target_end_location GO:0016020 ! membrane

[Term]
id: GO:0051674
name: localization of cell
namespace: biological_process
def: "Any process in which a cell is transported to, and/or maintained in, a specific location." [GOC:ai]
synonym: "cell localization" EXACT []
synonym: "establishment and maintenance of cell localization" EXACT []
synonym: "establishment and maintenance of localization of cell" EXACT []
synonym: "localisation of cell" EXACT [GOC:mah]
is_a: GO:0009987 ! cellular process
is_a: GO:0051179 ! localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input CL:0000000 ! cell
relationship: has_primary_input CL:0000000 ! cell

[Term]
id: GO:0051683
name: establishment of Golgi localization
namespace: biological_process
def: "The directed movement of the Golgi to a specific location." [GOC:ai]
synonym: "establishment of Golgi apparatus localization" EXACT []
synonym: "establishment of Golgi body localization" EXACT []
synonym: "establishment of Golgi localisation" EXACT [GOC:mah]
is_a: GO:0051645 ! Golgi localization
is_a: GO:0051649 ! establishment of localization in cell
is_a: GO:0051656 ! establishment of organelle localization
intersection_of: GO:0051234 ! establishment of localization
intersection_of: has_primary_input GO:0005794 ! Golgi apparatus

[Term]
id: GO:0051707
name: response to other organism
namespace: biological_process
alt_id: GO:0009613
alt_id: GO:0042828
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." [GOC:ai]
is_a: GO:0043207 ! response to external biotic stimulus
is_a: GO:0044419 ! biological process involved in interspecies interaction between organisms
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input NCBITaxon_Union:0000030
relationship: has_primary_input NCBITaxon_Union:0000030

[Term]
id: GO:0051716
name: cellular response to stimulus
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." [GOC:bf, GOC:jl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
is_a: GO:0009987 ! cellular process
is_a: GO:0050896 ! response to stimulus

[Term]
id: GO:0051726
name: regulation of cell cycle
namespace: biological_process
alt_id: GO:0000074
alt_id: GO:0007050
alt_id: GO:0071156
alt_id: GO:0071157
alt_id: GO:0071158
alt_id: GO:0071850
def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:ai, GOC:dph, GOC:tb]
subset: goslim_yeast
synonym: "arrest of mitotic cell cycle progression" NARROW [GOC:mah]
synonym: "cell cycle arrest" NARROW []
synonym: "cell cycle modulation" EXACT []
synonym: "cell cycle regulation" EXACT []
synonym: "cell cycle regulator" RELATED []
synonym: "control of cell cycle progression" EXACT []
synonym: "mitotic cell cycle arrest" NARROW []
synonym: "modulation of cell cycle progression" EXACT []
synonym: "negative regulation of cell cycle arrest" NARROW []
synonym: "positive regulation of cell cycle arrest" NARROW []
synonym: "regulation of cell cycle arrest" NARROW []
synonym: "regulation of cell cycle progression" EXACT []
synonym: "regulation of progression through cell cycle" EXACT []
synonym: "tumor suppressor" RELATED []
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007049 ! cell cycle
relationship: regulates GO:0007049 ! cell cycle

[Term]
id: GO:0051781
name: positive regulation of cell division
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell division." [GOC:ai]
synonym: "activation of cell division" NARROW []
synonym: "stimulation of cell division" NARROW []
synonym: "up regulation of cell division" EXACT []
synonym: "up-regulation of cell division" EXACT []
synonym: "upregulation of cell division" EXACT []
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051302 ! regulation of cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051301 ! cell division
relationship: positively_regulates GO:0051301 ! cell division

[Term]
id: GO:0051782
name: negative regulation of cell division
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." [GOC:ai]
synonym: "down regulation of cell division" EXACT []
synonym: "down-regulation of cell division" EXACT []
synonym: "downregulation of cell division" EXACT []
synonym: "inhibition of cell division" NARROW []
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051302 ! regulation of cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051301 ! cell division
relationship: negatively_regulates GO:0051301 ! cell division

[Term]
id: GO:0051783
name: regulation of nuclear division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai]
is_a: GO:0033043 ! regulation of organelle organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0000280 ! nuclear division
relationship: regulates GO:0000280 ! nuclear division

[Term]
id: GO:0051784
name: negative regulation of nuclear division
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai]
synonym: "down regulation of nuclear division" EXACT []
synonym: "down-regulation of nuclear division" EXACT []
synonym: "downregulation of nuclear division" EXACT []
synonym: "inhibition of nuclear division" NARROW []
is_a: GO:0010639 ! negative regulation of organelle organization
is_a: GO:0051783 ! regulation of nuclear division
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0000280 ! nuclear division
relationship: negatively_regulates GO:0000280 ! nuclear division

[Term]
id: GO:0051785
name: positive regulation of nuclear division
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai]
synonym: "activation of nuclear division" NARROW []
synonym: "stimulation of nuclear division" NARROW []
synonym: "up regulation of nuclear division" EXACT []
synonym: "up-regulation of nuclear division" EXACT []
synonym: "upregulation of nuclear division" EXACT []
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:0051783 ! regulation of nuclear division
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0000280 ! nuclear division
relationship: positively_regulates GO:0000280 ! nuclear division

[Term]
id: GO:0051875
name: pigment granule localization
namespace: biological_process
def: "Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell." [GOC:ai]
synonym: "pigment granule localisation" EXACT [GOC:mah]
is_a: GO:0051648 ! vesicle localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0048770 ! pigment granule
relationship: has_primary_input GO:0048770 ! pigment granule
relationship: part_of GO:0033059 ! cellular pigmentation

[Term]
id: GO:0051890
name: regulation of cardioblast differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai]
is_a: GO:1905207 ! regulation of cardiocyte differentiation
is_a: GO:2000736 ! regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010002 ! cardioblast differentiation
relationship: regulates GO:0010002 ! cardioblast differentiation

[Term]
id: GO:0051891
name: positive regulation of cardioblast differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai]
synonym: "activation of cardioblast differentiation" NARROW []
synonym: "stimulation of cardioblast differentiation" NARROW []
synonym: "up regulation of cardioblast differentiation" EXACT []
synonym: "up-regulation of cardioblast differentiation" EXACT []
synonym: "upregulation of cardioblast differentiation" EXACT []
is_a: GO:0051890 ! regulation of cardioblast differentiation
is_a: GO:1905209 ! positive regulation of cardiocyte differentiation
is_a: GO:2000738 ! positive regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010002 ! cardioblast differentiation
relationship: positively_regulates GO:0010002 ! cardioblast differentiation

[Term]
id: GO:0051892
name: negative regulation of cardioblast differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai]
synonym: "down regulation of cardioblast differentiation" EXACT []
synonym: "down-regulation of cardioblast differentiation" EXACT []
synonym: "downregulation of cardioblast differentiation" EXACT []
synonym: "inhibition of cardioblast differentiation" NARROW []
is_a: GO:0051890 ! regulation of cardioblast differentiation
is_a: GO:1905208 ! negative regulation of cardiocyte differentiation
is_a: GO:2000737 ! negative regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010002 ! cardioblast differentiation
relationship: negatively_regulates GO:0010002 ! cardioblast differentiation

[Term]
id: GO:0051904
name: pigment granule transport
namespace: biological_process
def: "The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "pigment granule translocation" EXACT []
is_a: GO:0006810 ! transport
is_a: GO:0051875 ! pigment granule localization
is_a: GO:0051905 ! establishment of pigment granule localization
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input GO:0048770 ! pigment granule

[Term]
id: GO:0051905
name: establishment of pigment granule localization
namespace: biological_process
def: "The directed movement of a pigment granule to a specific location." [GOC:ai]
synonym: "establishment of pigment granule localisation" EXACT [GOC:mah]
is_a: GO:0051650 ! establishment of vesicle localization
relationship: part_of GO:0051875 ! pigment granule localization

[Term]
id: GO:0051930
name: regulation of sensory perception of pain
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai]
is_a: GO:0051931 ! regulation of sensory perception
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0019233 ! sensory perception of pain
relationship: regulates GO:0019233 ! sensory perception of pain

[Term]
id: GO:0051931
name: regulation of sensory perception
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai]
is_a: GO:0031644 ! regulation of nervous system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007600 ! sensory perception
relationship: regulates GO:0007600 ! sensory perception

[Term]
id: GO:0051937
name: catecholamine transport
namespace: biological_process
def: "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, ISBN:0198506732]
is_a: GO:0015844 ! monoamine transport
is_a: GO:0015850 ! organic hydroxy compound transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:33567 ! catecholamine
relationship: has_primary_input CHEBI:33567 ! catecholamine

[Term]
id: GO:0051952
name: regulation of amine transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0015837 ! amine transport
relationship: regulates GO:0015837 ! amine transport

[Term]
id: GO:0051953
name: negative regulation of amine transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "down regulation of amine transport" EXACT []
synonym: "down-regulation of amine transport" EXACT []
synonym: "downregulation of amine transport" EXACT []
synonym: "inhibition of amine transport" NARROW []
is_a: GO:0051051 ! negative regulation of transport
is_a: GO:0051952 ! regulation of amine transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0015837 ! amine transport
relationship: negatively_regulates GO:0015837 ! amine transport

[Term]
id: GO:0051954
name: positive regulation of amine transport
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "activation of amine transport" NARROW []
synonym: "stimulation of amine transport" NARROW []
synonym: "up regulation of amine transport" EXACT []
synonym: "up-regulation of amine transport" EXACT []
synonym: "upregulation of amine transport" EXACT []
is_a: GO:0051050 ! positive regulation of transport
is_a: GO:0051952 ! regulation of amine transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0015837 ! amine transport
relationship: positively_regulates GO:0015837 ! amine transport

[Term]
id: GO:0051955
name: regulation of amino acid transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
is_a: GO:0032890 ! regulation of organic acid transport
is_a: GO:0051952 ! regulation of amine transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006865 ! amino acid transport
relationship: regulates GO:0006865 ! amino acid transport

[Term]
id: GO:0051956
name: negative regulation of amino acid transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "down regulation of amino acid transport" EXACT []
synonym: "down-regulation of amino acid transport" EXACT []
synonym: "downregulation of amino acid transport" EXACT []
synonym: "inhibition of amino acid transport" NARROW []
synonym: "negative regulation of amino acid transmembrane transport" EXACT [GOC:mah]
is_a: GO:0032891 ! negative regulation of organic acid transport
is_a: GO:0051953 ! negative regulation of amine transport
is_a: GO:0051955 ! regulation of amino acid transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006865 ! amino acid transport
relationship: negatively_regulates GO:0006865 ! amino acid transport

[Term]
id: GO:0051957
name: positive regulation of amino acid transport
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]
synonym: "activation of amino acid transport" NARROW []
synonym: "positive regulation of amino acid transmembrane transport" EXACT [GOC:mah]
synonym: "stimulation of amino acid transport" NARROW []
synonym: "up regulation of amino acid transport" EXACT []
synonym: "up-regulation of amino acid transport" EXACT []
synonym: "upregulation of amino acid transport" EXACT []
is_a: GO:0032892 ! positive regulation of organic acid transport
is_a: GO:0051954 ! positive regulation of amine transport
is_a: GO:0051955 ! regulation of amino acid transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006865 ! amino acid transport
relationship: positively_regulates GO:0006865 ! amino acid transport

[Term]
id: GO:0051960
name: regulation of nervous system development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai]
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007399 ! nervous system development
relationship: regulates GO:0007399 ! nervous system development

[Term]
id: GO:0051961
name: negative regulation of nervous system development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai]
synonym: "down regulation of nervous system development" EXACT []
synonym: "down-regulation of nervous system development" EXACT []
synonym: "downregulation of nervous system development" EXACT []
synonym: "inhibition of nervous system development" NARROW []
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0051960 ! regulation of nervous system development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007399 ! nervous system development
relationship: negatively_regulates GO:0007399 ! nervous system development

[Term]
id: GO:0051962
name: positive regulation of nervous system development
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai]
synonym: "activation of nervous system development" NARROW []
synonym: "stimulation of nervous system development" NARROW []
synonym: "up regulation of nervous system development" EXACT []
synonym: "up-regulation of nervous system development" EXACT []
synonym: "upregulation of nervous system development" EXACT []
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:0051960 ! regulation of nervous system development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007399 ! nervous system development
relationship: positively_regulates GO:0007399 ! nervous system development

[Term]
id: GO:0051963
name: regulation of synapse assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr]
subset: goslim_synapse
synonym: "regulation of synapse biogenesis" EXACT []
synonym: "regulation of synaptogenesis" EXACT []
is_a: GO:0050807 ! regulation of synapse organization
is_a: GO:1901888 ! regulation of cell junction assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007416 ! synapse assembly
relationship: regulates GO:0007416 ! synapse assembly

[Term]
id: GO:0051964
name: negative regulation of synapse assembly
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr]
synonym: "down regulation of synapse assembly" EXACT []
synonym: "down-regulation of synapse assembly" EXACT []
synonym: "downregulation of synapse assembly" EXACT []
synonym: "inhibition of synapse assembly" NARROW []
synonym: "negative regulation of synapse biogenesis" EXACT []
synonym: "negative regulation of synaptogenesis" EXACT []
is_a: GO:0051961 ! negative regulation of nervous system development
is_a: GO:0051963 ! regulation of synapse assembly
is_a: GO:1901889 ! negative regulation of cell junction assembly
is_a: GO:1905809 ! negative regulation of synapse organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007416 ! synapse assembly
relationship: negatively_regulates GO:0007416 ! synapse assembly

[Term]
id: GO:0051965
name: positive regulation of synapse assembly
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr]
synonym: "activation of synapse assembly" NARROW []
synonym: "positive regulation of synapse biogenesis" EXACT []
synonym: "positive regulation of synaptogenesis" EXACT []
synonym: "stimulation of synapse assembly" NARROW []
synonym: "up regulation of synapse assembly" EXACT []
synonym: "up-regulation of synapse assembly" EXACT []
synonym: "upregulation of synapse assembly" EXACT []
is_a: GO:0051962 ! positive regulation of nervous system development
is_a: GO:0051963 ! regulation of synapse assembly
is_a: GO:1901890 ! positive regulation of cell junction assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007416 ! synapse assembly
relationship: positively_regulates GO:0007416 ! synapse assembly

[Term]
id: GO:0051969
name: regulation of transmission of nerve impulse
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai]
synonym: "regulation of conduction of nerve impulse" EXACT [GOC:dph]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0031644 ! regulation of nervous system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0019226 ! transmission of nerve impulse
relationship: regulates GO:0019226 ! transmission of nerve impulse

[Term]
id: GO:0051970
name: negative regulation of transmission of nerve impulse
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai]
synonym: "down regulation of transmission of nerve impulse" EXACT []
synonym: "down-regulation of transmission of nerve impulse" EXACT []
synonym: "downregulation of transmission of nerve impulse" EXACT []
synonym: "inhibition of transmission of nerve impulse" NARROW []
synonym: "negative regulation of conduction of nerve impulse" EXACT [GOC:dph]
is_a: GO:0010648 ! negative regulation of cell communication
is_a: GO:0031645 ! negative regulation of nervous system process
is_a: GO:0051969 ! regulation of transmission of nerve impulse
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0019226 ! transmission of nerve impulse
relationship: negatively_regulates GO:0019226 ! transmission of nerve impulse

[Term]
id: GO:0051971
name: positive regulation of transmission of nerve impulse
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai]
synonym: "activation of transmission of nerve impulse" NARROW []
synonym: "positive regulation of conduction of nerve impulse" EXACT [GOC:dph]
synonym: "stimulation of transmission of nerve impulse" NARROW []
synonym: "up regulation of transmission of nerve impulse" EXACT []
synonym: "up-regulation of transmission of nerve impulse" EXACT []
synonym: "upregulation of transmission of nerve impulse" EXACT []
is_a: GO:0010647 ! positive regulation of cell communication
is_a: GO:0031646 ! positive regulation of nervous system process
is_a: GO:0051969 ! regulation of transmission of nerve impulse
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0019226 ! transmission of nerve impulse
relationship: positively_regulates GO:0019226 ! transmission of nerve impulse

[Term]
id: GO:0051983
name: regulation of chromosome segregation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai]
is_a: GO:0010564 ! regulation of cell cycle process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007059 ! chromosome segregation
relationship: regulates GO:0007059 ! chromosome segregation

[Term]
id: GO:0051984
name: positive regulation of chromosome segregation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai]
synonym: "activation of chromosome segregation" NARROW []
synonym: "stimulation of chromosome segregation" NARROW []
synonym: "up regulation of chromosome segregation" EXACT []
synonym: "up-regulation of chromosome segregation" EXACT []
synonym: "upregulation of chromosome segregation" EXACT []
is_a: GO:0051983 ! regulation of chromosome segregation
is_a: GO:0090068 ! positive regulation of cell cycle process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007059 ! chromosome segregation
relationship: positively_regulates GO:0007059 ! chromosome segregation

[Term]
id: GO:0051985
name: negative regulation of chromosome segregation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai]
synonym: "down regulation of chromosome segregation" EXACT []
synonym: "down-regulation of chromosome segregation" EXACT []
synonym: "downregulation of chromosome segregation" EXACT []
synonym: "inhibition of chromosome segregation" NARROW []
is_a: GO:0010948 ! negative regulation of cell cycle process
is_a: GO:0051983 ! regulation of chromosome segregation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007059 ! chromosome segregation
relationship: negatively_regulates GO:0007059 ! chromosome segregation

[Term]
id: GO:0055001
name: muscle cell development
namespace: biological_process
alt_id: GO:0048747
def: "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." [CL:0000187, GOC:devbiol]
synonym: "muscle fiber development" EXACT []
synonym: "muscle fibre development" EXACT []
synonym: "myofiber development" EXACT []
synonym: "myofibre development" EXACT []
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000187 ! muscle cell
relationship: part_of GO:0042692 ! muscle cell differentiation
relationship: results_in_development_of CL:0000187 ! muscle cell

[Term]
id: GO:0055002
name: striated muscle cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:devbiol]
is_a: GO:0055001 ! muscle cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000737 ! striated muscle cell
relationship: part_of GO:0051146 ! striated muscle cell differentiation
relationship: results_in_development_of CL:0000737 ! striated muscle cell

[Term]
id: GO:0055003
name: cardiac myofibril assembly
namespace: biological_process
def: "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol]
synonym: "cardiac myofibril development" EXACT []
synonym: "cardiac myofibril morphogenesis" EXACT []
synonym: "heart myofibril assembly" RELATED []
is_a: GO:0030239 ! myofibril assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0097512 ! cardiac myofibril
relationship: part_of GO:0055013 ! cardiac muscle cell development
relationship: results_in_assembly_of GO:0097512 ! cardiac myofibril

[Term]
id: GO:0055006
name: cardiac cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual." [GOC:devbiol]
synonym: "cardiocyte development" EXACT [GOC:dph]
synonym: "heart cell development" RELATED []
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0002494 ! cardiocyte
relationship: part_of GO:0035051 ! cardiocyte differentiation
relationship: results_in_development_of CL:0002494 ! cardiocyte

[Term]
id: GO:0055007
name: cardiac muscle cell differentiation
namespace: biological_process
def: "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:devbiol, GOC:mtg_heart]
synonym: "cardiomyocyte differentiation" EXACT []
synonym: "heart muscle cell differentiation" RELATED []
is_a: GO:0035051 ! cardiocyte differentiation
is_a: GO:0051146 ! striated muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000746 ! cardiac muscle cell
relationship: part_of GO:0048738 ! cardiac muscle tissue development
relationship: results_in_acquisition_of_features_of CL:0000746 ! cardiac muscle cell

[Term]
id: GO:0055008
name: cardiac muscle tissue morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of cardiac muscle tissue are generated and organized." [GOC:devbiol]
synonym: "heart muscle morphogenesis" EXACT []
synonym: "myocardium morphogenesis" BROAD [GOC:mtg_heart]
is_a: GO:0060415 ! muscle tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001133 ! cardiac muscle tissue
relationship: part_of GO:0003007 ! heart morphogenesis
relationship: part_of GO:0048738 ! cardiac muscle tissue development
relationship: results_in_morphogenesis_of UBERON:0001133 ! cardiac muscle tissue

[Term]
id: GO:0055009
name: atrial cardiac muscle tissue morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of cardiac atrium muscle is generated and organized." [GOC:devbiol]
synonym: "atrial heart muscle morphogenesis" EXACT []
synonym: "atrial myocardium morphogenesis" EXACT [GOC:mtg_heart]
synonym: "cardiac atrium muscle morphogenesis" EXACT []
is_a: GO:0055008 ! cardiac muscle tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004490 ! cardiac muscle tissue of atrium
relationship: part_of GO:0003209 ! cardiac atrium morphogenesis
relationship: part_of GO:0003228 ! atrial cardiac muscle tissue development
relationship: results_in_morphogenesis_of UBERON:0004490 ! cardiac muscle tissue of atrium

[Term]
id: GO:0055010
name: ventricular cardiac muscle tissue morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized." [GOC:devbiol]
synonym: "cardiac ventricle muscle morphogenesis" EXACT []
synonym: "ventricular heart muscle morphogenesis" EXACT []
is_a: GO:0055008 ! cardiac muscle tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0018649 ! cardiac muscle tissue of ventricle
relationship: part_of GO:0003208 ! cardiac ventricle morphogenesis
relationship: part_of GO:0003229 ! ventricular cardiac muscle tissue development
relationship: results_in_morphogenesis_of UBERON:0018649 ! cardiac muscle tissue of ventricle

[Term]
id: GO:0055013
name: cardiac muscle cell development
namespace: biological_process
alt_id: GO:0048739
def: "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state." [GOC:devbiol, GOC:mtg_heart]
synonym: "cardiac muscle fiber development" EXACT []
synonym: "cardiac muscle fibre development" EXACT []
synonym: "cardiomyocyte cell development" EXACT [GOC:mtg_muscle]
synonym: "heart muscle cell development" EXACT []
synonym: "heart muscle fiber development" RELATED []
is_a: GO:0055002 ! striated muscle cell development
is_a: GO:0055006 ! cardiac cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000746 ! cardiac muscle cell
relationship: part_of GO:0055007 ! cardiac muscle cell differentiation
relationship: results_in_development_of CL:0000746 ! cardiac muscle cell

[Term]
id: GO:0055017
name: cardiac muscle tissue growth
namespace: biological_process
def: "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:devbiol]
synonym: "heart muscle growth" EXACT []
is_a: GO:0048589 ! developmental growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: results_in_growth_of UBERON:0001133 ! cardiac muscle tissue
relationship: part_of GO:0048738 ! cardiac muscle tissue development
relationship: part_of GO:0060419 ! heart growth
relationship: results_in_growth_of UBERON:0001133 ! cardiac muscle tissue

[Term]
id: GO:0055018
name: regulation of cardiac muscle fiber development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk]
synonym: "regulation of cardiac muscle fibre development" EXACT []
synonym: "regulation of heart muscle fiber development" EXACT []
is_a: GO:0060284 ! regulation of cell development
is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0055013 ! cardiac muscle cell development
relationship: regulates GO:0055013 ! cardiac muscle cell development

[Term]
id: GO:0055019
name: negative regulation of cardiac muscle fiber development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk]
synonym: "down regulation of cardiac muscle fiber development" EXACT []
synonym: "down-regulation of cardiac muscle fiber development" EXACT []
synonym: "downregulation of cardiac muscle fiber development" EXACT []
synonym: "inhibition of cardiac muscle fiber development" NARROW []
synonym: "negative regulation of cardiac muscle fibre development" EXACT []
synonym: "negative regulation of heart muscle fiber development" RELATED []
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation
is_a: GO:0055018 ! regulation of cardiac muscle fiber development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0055013 ! cardiac muscle cell development
relationship: negatively_regulates GO:0055013 ! cardiac muscle cell development

[Term]
id: GO:0055020
name: positive regulation of cardiac muscle fiber development
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk]
synonym: "activation of cardiac muscle fiber development" NARROW []
synonym: "positive regulation of cardiac muscle fibre development" EXACT []
synonym: "positive regulation of heart muscle fiber development" EXACT []
synonym: "stimulation of cardiac muscle fiber development" NARROW []
synonym: "up regulation of cardiac muscle fiber development" EXACT []
synonym: "up-regulation of cardiac muscle fiber development" EXACT []
synonym: "upregulation of cardiac muscle fiber development" EXACT []
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0055018 ! regulation of cardiac muscle fiber development
is_a: GO:2000727 ! positive regulation of cardiac muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0055013 ! cardiac muscle cell development
relationship: positively_regulates GO:0055013 ! cardiac muscle cell development

[Term]
id: GO:0055021
name: regulation of cardiac muscle tissue growth
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac muscle growth." [GOC:vk]
is_a: GO:0060420 ! regulation of heart growth
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0055017 ! cardiac muscle tissue growth
relationship: regulates GO:0055017 ! cardiac muscle tissue growth

[Term]
id: GO:0055022
name: negative regulation of cardiac muscle tissue growth
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth." [GOC:vk]
synonym: "down regulation of cardiac muscle growth" EXACT []
synonym: "down-regulation of cardiac muscle growth" EXACT []
synonym: "downregulation of cardiac muscle growth" EXACT []
synonym: "inhibition of cardiac muscle growth" NARROW []
synonym: "negative regulation of heart muscle growth" RELATED []
is_a: GO:0055021 ! regulation of cardiac muscle tissue growth
is_a: GO:0061117 ! negative regulation of heart growth
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0055017 ! cardiac muscle tissue growth
relationship: negatively_regulates GO:0055017 ! cardiac muscle tissue growth

[Term]
id: GO:0055023
name: positive regulation of cardiac muscle tissue growth
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth." [GOC:vk]
synonym: "activation of cardiac muscle growth" NARROW []
synonym: "positive regulation of heart muscle growth" EXACT []
synonym: "stimulation of cardiac muscle growth" NARROW []
synonym: "up regulation of cardiac muscle growth" EXACT []
synonym: "up-regulation of cardiac muscle growth" EXACT []
synonym: "upregulation of cardiac muscle growth" EXACT []
is_a: GO:0055021 ! regulation of cardiac muscle tissue growth
is_a: GO:0060421 ! positive regulation of heart growth
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0055017 ! cardiac muscle tissue growth
relationship: positively_regulates GO:0055017 ! cardiac muscle tissue growth

[Term]
id: GO:0055024
name: regulation of cardiac muscle tissue development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk]
synonym: "regulation of heart muscle development" EXACT []
is_a: GO:0016202 ! regulation of striated muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048738 ! cardiac muscle tissue development
relationship: regulates GO:0048738 ! cardiac muscle tissue development

[Term]
id: GO:0055025
name: positive regulation of cardiac muscle tissue development
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk]
synonym: "activation of cardiac muscle development" NARROW []
synonym: "positive regulation of heart muscle development" EXACT []
synonym: "stimulation of cardiac muscle development" NARROW []
synonym: "up regulation of cardiac muscle development" EXACT []
synonym: "up-regulation of cardiac muscle development" EXACT []
synonym: "upregulation of cardiac muscle development" EXACT []
is_a: GO:0045844 ! positive regulation of striated muscle tissue development
is_a: GO:0055024 ! regulation of cardiac muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048738 ! cardiac muscle tissue development
relationship: positively_regulates GO:0048738 ! cardiac muscle tissue development

[Term]
id: GO:0055026
name: negative regulation of cardiac muscle tissue development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk]
synonym: "down regulation of cardiac muscle development" EXACT []
synonym: "down-regulation of cardiac muscle development" EXACT []
synonym: "downregulation of cardiac muscle development" EXACT []
synonym: "inhibition of cardiac muscle development" NARROW []
synonym: "negative regulation of heart muscle development" EXACT []
is_a: GO:0045843 ! negative regulation of striated muscle tissue development
is_a: GO:0055024 ! regulation of cardiac muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048738 ! cardiac muscle tissue development
relationship: negatively_regulates GO:0048738 ! cardiac muscle tissue development

[Term]
id: GO:0055057
name: neuroblast division
namespace: biological_process
def: "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron." [PMID:11163136, PMID:11250167]
synonym: "neuroblast cell division" EXACT []
is_a: GO:0051301 ! cell division
intersection_of: GO:0051301 ! cell division
intersection_of: has_primary_input CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: has_primary_input CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: part_of GO:0007405 ! neuroblast proliferation

[Term]
id: GO:0055059
name: asymmetric neuroblast division
namespace: biological_process
def: "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." [GOC:dph]
is_a: GO:0008356 ! asymmetric cell division
is_a: GO:0045165 ! cell fate commitment
is_a: GO:0055057 ! neuroblast division
intersection_of: GO:0008356 ! asymmetric cell division
intersection_of: has_primary_input CL:0000031 ! neuroblast (sensu Vertebrata)

[Term]
id: GO:0055085
name: transmembrane transport
namespace: biological_process
alt_id: GO:0090662
def: "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:dph, GOC:jid]
comment: Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes.
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pombe
subset: goslim_yeast
synonym: "ATP hydrolysis coupled transmembrane transport" NARROW []
synonym: "membrane transport" EXACT []
is_a: GO:0006810 ! transport
is_a: GO:0009987 ! cellular process
intersection_of: GO:0006810 ! transport
intersection_of: results_in_transport_across GO:0016020 ! membrane
relationship: results_in_transport_across GO:0016020 ! membrane
created_by: tb
creation_date: 2015-10-21T13:22:47Z

[Term]
id: GO:0055086
name: nucleobase-containing small molecule metabolic process
namespace: biological_process
def: "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:vw]
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pombe
subset: goslim_prokaryote
subset: goslim_yeast
synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED []
synonym: "nucleobase, nucleoside and nucleotide metabolism" EXACT []
is_a: GO:0006139 ! nucleobase-containing compound metabolic process
is_a: GO:0044281 ! small molecule metabolic process

[Term]
id: GO:0055107
name: Golgi to secretory granule transport
namespace: biological_process
def: "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex." [GOC:curators]
is_a: GO:0046907 ! intracellular transport
intersection_of: GO:0006810 ! transport
intersection_of: has_target_end_location GO:0030141 ! secretory granule
intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus
intersection_of: occurs_in GO:0005737 ! cytoplasm
relationship: has_target_end_location GO:0030141 ! secretory granule
relationship: has_target_start_location GO:0005794 ! Golgi apparatus
relationship: occurs_in GO:0005737 ! cytoplasm

[Term]
id: GO:0055108
name: Golgi to transport vesicle transport
namespace: biological_process
def: "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis." [GOC:jid]
is_a: GO:0046907 ! intracellular transport
intersection_of: GO:0006810 ! transport
intersection_of: has_target_end_location GO:0030133 ! transport vesicle
intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus
intersection_of: occurs_in GO:0005737 ! cytoplasm
relationship: has_target_end_location GO:0030133 ! transport vesicle
relationship: has_target_start_location GO:0005794 ! Golgi apparatus
relationship: occurs_in GO:0005737 ! cytoplasm
relationship: part_of GO:0048193 ! Golgi vesicle transport

[Term]
id: GO:0055111
name: ingression involved in gastrulation with mouth forming second
namespace: biological_process
def: "The migration of individual cells into the embryo involved in deuterostomic gastrulation." [ISBN:0878932437]
is_a: GO:0042074 ! cell migration involved in gastrulation
intersection_of: GO:0001667 ! ameboidal-type cell migration
intersection_of: part_of GO:0001702 ! gastrulation with mouth forming second
relationship: part_of GO:0001702 ! gastrulation with mouth forming second

[Term]
id: GO:0055117
name: regulation of cardiac muscle contraction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd]
is_a: GO:0006942 ! regulation of striated muscle contraction
is_a: GO:0008016 ! regulation of heart contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060048 ! cardiac muscle contraction
relationship: regulates GO:0060048 ! cardiac muscle contraction

[Term]
id: GO:0055118
name: negative regulation of cardiac muscle contraction
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd]
is_a: GO:0045822 ! negative regulation of heart contraction
is_a: GO:0045988 ! negative regulation of striated muscle contraction
is_a: GO:0055117 ! regulation of cardiac muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060048 ! cardiac muscle contraction
relationship: negatively_regulates GO:0060048 ! cardiac muscle contraction

[Term]
id: GO:0055123
name: digestive system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jid]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001007 ! digestive system
relationship: results_in_development_of UBERON:0001007 ! digestive system

[Term]
id: GO:0060008
name: Sertoli cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0030855 ! epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000216 ! Sertoli cell
relationship: part_of GO:0008584 ! male gonad development
relationship: results_in_acquisition_of_features_of CL:0000216 ! Sertoli cell

[Term]
id: GO:0060009
name: Sertoli cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate." [GOC:dph]
is_a: GO:0002064 ! epithelial cell development
is_a: GO:0003006 ! developmental process involved in reproduction
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000216 ! Sertoli cell
relationship: part_of GO:0060008 ! Sertoli cell differentiation
relationship: results_in_development_of CL:0000216 ! Sertoli cell

[Term]
id: GO:0060011
name: Sertoli cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph]
is_a: GO:0022414 ! reproductive process
is_a: GO:0050673 ! epithelial cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000216 ! Sertoli cell
relationship: acts_on_population_of CL:0000216 ! Sertoli cell
relationship: part_of GO:0008584 ! male gonad development

[Term]
id: GO:0060021
name: roof of mouth development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities." [GOC:dph, ISBN:0721662544]
synonym: "palatum development" EXACT [ISBN:0721662544]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0007375 ! roof of mouth
relationship: results_in_development_of UBERON:0007375 ! roof of mouth

[Term]
id: GO:0060037
name: pharyngeal system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear." [GOC:dph]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0008814 ! pharyngeal arch system
relationship: part_of GO:0043009 ! chordate embryonic development
relationship: results_in_development_of UBERON:0008814 ! pharyngeal arch system

[Term]
id: GO:0060038
name: cardiac muscle cell proliferation
namespace: biological_process
def: "The expansion of a cardiac muscle cell population by cell division." [GOC:dph, GOC:rph, PMID:11161571]
synonym: "cardiac myocyte proliferation" EXACT []
synonym: "cardiomyocyte proliferation" RELATED [GOC:dph, PMID:10074473]
synonym: "heart muscle cell proliferation" EXACT []
is_a: GO:0014855 ! striated muscle cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000746 ! cardiac muscle cell
relationship: acts_on_population_of CL:0000746 ! cardiac muscle cell
relationship: part_of GO:0055017 ! cardiac muscle tissue growth

[Term]
id: GO:0060039
name: pericardium development
namespace: biological_process
def: "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery." [GOC:dph, GOC:rph, PMID:15138308, PMID:16376438]
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002407 ! pericardium
relationship: part_of GO:0007507 ! heart development
relationship: results_in_development_of UBERON:0002407 ! pericardium

[Term]
id: GO:0060041
name: retina development in camera-type eye
namespace: biological_process
alt_id: GO:0002073
def: "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:bf, GOC:dph, ISBN:0815340729]
synonym: "retina development in camera-style eye" EXACT []
synonym: "retinal development" RELATED [GOC:dph, GOC:tb]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: part_of GO:0043010 ! camera-type eye development
intersection_of: results_in_development_of UBERON:0000966 ! retina
relationship: part_of GO:0043010 ! camera-type eye development
relationship: results_in_development_of UBERON:0000966 ! retina

[Term]
id: GO:0060042
name: retina morphogenesis in camera-type eye
namespace: biological_process
def: "The process in which the anatomical structure of the retina is generated and organized." [GOC:bf, GOC:dph, GOC:mtg_sensu]
synonym: "retina morphogenesis in camera-style eye" EXACT []
synonym: "retinogenesis" EXACT []
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000966 ! retina
relationship: part_of GO:0048593 ! camera-type eye morphogenesis
relationship: part_of GO:0060041 ! retina development in camera-type eye
relationship: results_in_morphogenesis_of UBERON:0000966 ! retina

[Term]
id: GO:0060043
name: regulation of cardiac muscle cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph]
synonym: "regulation of cardiomyocyte proliferation" RELATED [GOC:dph]
synonym: "regulation of heart muscle cell proliferation" EXACT []
is_a: GO:0042127 ! regulation of cell population proliferation
is_a: GO:0055021 ! regulation of cardiac muscle tissue growth
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060038 ! cardiac muscle cell proliferation
relationship: regulates GO:0060038 ! cardiac muscle cell proliferation

[Term]
id: GO:0060044
name: negative regulation of cardiac muscle cell proliferation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph]
synonym: "negative regulation of heart muscle cell proliferation" EXACT []
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth
is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060038 ! cardiac muscle cell proliferation
relationship: negatively_regulates GO:0060038 ! cardiac muscle cell proliferation

[Term]
id: GO:0060045
name: positive regulation of cardiac muscle cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph]
synonym: "positive regulation of heart muscle cell proliferation" RELATED []
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth
is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060038 ! cardiac muscle cell proliferation
relationship: positively_regulates GO:0060038 ! cardiac muscle cell proliferation

[Term]
id: GO:0060047
name: heart contraction
namespace: biological_process
def: "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph]
synonym: "cardiac contraction" RELATED []
synonym: "heart beating" EXACT []
synonym: "hemolymph circulation" RELATED []
is_a: GO:0003015 ! heart process
relationship: part_of GO:0008015 ! blood circulation

[Term]
id: GO:0060048
name: cardiac muscle contraction
namespace: biological_process
def: "Muscle contraction of cardiac muscle tissue." [GOC:dph]
synonym: "heart muscle contraction" EXACT []
is_a: GO:0006941 ! striated muscle contraction
intersection_of: GO:0006936 ! muscle contraction
intersection_of: occurs_in UBERON:0001133 ! cardiac muscle tissue
relationship: occurs_in UBERON:0001133 ! cardiac muscle tissue
relationship: part_of GO:0060047 ! heart contraction

[Term]
id: GO:0060065
name: uterus development
namespace: biological_process
def: "The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure." [GOC:dph, GOC:ebc]
synonym: "Mullerian tract development" RELATED []
is_a: GO:0048513 ! animal organ development
is_a: GO:0048608 ! reproductive structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000995 ! uterus
relationship: results_in_development_of UBERON:0000995 ! uterus

[Term]
id: GO:0060066
name: oviduct development
namespace: biological_process
def: "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:dph, GOC:ebc, http://www.thefreedictionary.com/oviduct]
synonym: "fallopian tube development" NARROW [GOC:bf]
synonym: "Mullerian tract development" RELATED []
is_a: GO:0035295 ! tube development
is_a: GO:0048608 ! reproductive structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003889 ! fallopian tube
relationship: results_in_development_of UBERON:0003889 ! fallopian tube

[Term]
id: GO:0060073
name: micturition
namespace: biological_process
def: "The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body." [GOC:dph]
synonym: "urination" EXACT []
synonym: "urine voiding" EXACT []
xref: Wikipedia:Urination
is_a: GO:0003014 ! renal system process
is_a: GO:0007588 ! excretion

[Term]
id: GO:0060083
name: smooth muscle contraction involved in micturition
namespace: biological_process
def: "The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body." [GOC:dph, PMID:15827347]
synonym: "smooth muscle contraction involved in urination" RELATED []
synonym: "urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:dph]
is_a: GO:0014832 ! urinary bladder smooth muscle contraction
intersection_of: GO:0006939 ! smooth muscle contraction
intersection_of: part_of GO:0060073 ! micturition
relationship: part_of GO:0060073 ! micturition

[Term]
id: GO:0060084
name: synaptic transmission involved in micturition
namespace: biological_process
def: "The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body." [GOC:dph, PMID:15827347]
synonym: "synaptic transmission involved in urination" RELATED []
is_a: GO:0007274 ! neuromuscular synaptic transmission
intersection_of: GO:0007268 ! chemical synaptic transmission
intersection_of: part_of GO:0060073 ! micturition
relationship: part_of GO:0060073 ! micturition

[Term]
id: GO:0060096
name: serotonin secretion, neurotransmission
namespace: biological_process
def: "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter." [GOC:dph]
synonym: "serotonin release, neurotransmission" RELATED [GOC:tb]
is_a: GO:0001820 ! serotonin secretion
is_a: GO:0007269 ! neurotransmitter secretion
intersection_of: GO:0007269 ! neurotransmitter secretion
intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+)

[Term]
id: GO:0060135
name: maternal process involved in female pregnancy
namespace: biological_process
def: "A reproductive process occurring in the mother that allows an embryo or fetus to develop within it." [GOC:dph]
is_a: GO:0048609 ! multicellular organismal reproductive process
relationship: part_of GO:0007565 ! female pregnancy

[Term]
id: GO:0060136
name: embryonic process involved in female pregnancy
namespace: biological_process
def: "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother." [GOC:dph]
is_a: GO:0048609 ! multicellular organismal reproductive process
intersection_of: GO:0022414 ! reproductive process
intersection_of: part_of GO:0007565 ! female pregnancy
intersection_of: part_of GO:0009790 ! embryo development
relationship: part_of GO:0007565 ! female pregnancy
relationship: part_of GO:0009792 ! embryo development ending in birth or egg hatching

[Term]
id: GO:0060142
name: regulation of syncytium formation by plasma membrane fusion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph]
is_a: GO:0050793 ! regulation of developmental process
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0000768 ! syncytium formation by plasma membrane fusion
relationship: regulates GO:0000768 ! syncytium formation by plasma membrane fusion

[Term]
id: GO:0060143
name: positive regulation of syncytium formation by plasma membrane fusion
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051130 ! positive regulation of cellular component organization
is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion
relationship: positively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion

[Term]
id: GO:0060157
name: urinary bladder development
namespace: biological_process
def: "The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion." [GOC:dph, GOC:ln, GOC:mr, PMID:11768524, PMID:18276178, PMID:538956]
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001255 ! urinary bladder
relationship: part_of GO:0072001 ! renal system development
relationship: results_in_development_of UBERON:0001255 ! urinary bladder
property_value: RO:0002161 NCBITaxon:8782

[Term]
id: GO:0060170
name: ciliary membrane
namespace: cellular_component
alt_id: GO:0020017
def: "The portion of the plasma membrane surrounding a cilium." [GOC:cilia, GOC:dph, GOC:rph]
comment: Note that cilia and eukaryotic flagella are deemed to be equivalent.
synonym: "cilial membrane" EXACT []
synonym: "cilium membrane" EXACT []
synonym: "flagellar membrane" NARROW []
synonym: "flagellum membrane" NARROW []
is_a: GO:0031253 ! cell projection membrane
is_a: GO:0098588 ! bounding membrane of organelle
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0005929 ! cilium
relationship: bounding_layer_of GO:0005929 ! cilium
relationship: part_of GO:0005929 ! cilium

[Term]
id: GO:0060173
name: limb development
namespace: biological_process
def: "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin." [GOC:dgh, GOC:dph, PMID:11487378]
synonym: "limb bud development" NARROW [GOC:dph]
synonym: "paired limb/fin development" EXACT []
xref: Wikipedia:Limb_development
is_a: GO:0048736 ! appendage development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004708 ! paired limb/fin
relationship: results_in_development_of UBERON:0004708 ! paired limb/fin

[Term]
id: GO:0060214
name: endocardium formation
namespace: biological_process
def: "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:bf, GOC:dph, PMID:17722983]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002165 ! endocardium
relationship: part_of GO:0003160 ! endocardium morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002165 ! endocardium

[Term]
id: GO:0060218
name: hematopoietic stem cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:bf, GOC:BHF, GOC:dph, GOC:rl, PMID:15378083]
synonym: "haematopoietic stem cell differentiation" EXACT []
synonym: "haemopoietic stem cell differentiation" EXACT []
synonym: "hemopoietic stem cell differentiation" EXACT []
is_a: GO:0002244 ! hematopoietic progenitor cell differentiation
is_a: GO:0048863 ! stem cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000037 ! hematopoietic stem cell
relationship: results_in_acquisition_of_features_of CL:0000037 ! hematopoietic stem cell

[Term]
id: GO:0060219
name: camera-type eye photoreceptor cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0001754 ! eye photoreceptor cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0010009 ! camera-type eye photoreceptor cell
relationship: part_of GO:0003407 ! neural retina development
relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye
relationship: results_in_acquisition_of_features_of CL:0010009 ! camera-type eye photoreceptor cell

[Term]
id: GO:0060221
name: retinal rod cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell." [GOC:dph]
is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000604 ! retinal rod cell
relationship: results_in_acquisition_of_features_of CL:0000604 ! retinal rod cell

[Term]
id: GO:0060231
name: mesenchymal to epithelial transition
namespace: biological_process
def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
synonym: "epithelial cell differentiation from mesenchymal cell" EXACT [GOC:BHF, GOC:dph, GOC:rl]
synonym: "mesenchymal-epithelial transition" EXACT [GOC:dph]
is_a: GO:0030855 ! epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: has_primary_input CL:0008019 ! mesenchymal cell
intersection_of: results_in_acquisition_of_features_of CL:0000066 ! epithelial cell
relationship: has_primary_input CL:0008019 ! mesenchymal cell

[Term]
id: GO:0060251
name: regulation of glial cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of glial cell proliferation." [GOC:dph, GOC:tb]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014009 ! glial cell proliferation
relationship: regulates GO:0014009 ! glial cell proliferation

[Term]
id: GO:0060252
name: positive regulation of glial cell proliferation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0014015 ! positive regulation of gliogenesis
is_a: GO:0060251 ! regulation of glial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014009 ! glial cell proliferation
relationship: positively_regulates GO:0014009 ! glial cell proliferation

[Term]
id: GO:0060253
name: negative regulation of glial cell proliferation
namespace: biological_process
def: "Any process that stops or decreases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0014014 ! negative regulation of gliogenesis
is_a: GO:0060251 ! regulation of glial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014009 ! glial cell proliferation
relationship: negatively_regulates GO:0014009 ! glial cell proliferation

[Term]
id: GO:0060255
name: regulation of macromolecule metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb]
is_a: GO:0019222 ! regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0043170 ! macromolecule metabolic process
relationship: regulates GO:0043170 ! macromolecule metabolic process

[Term]
id: GO:0060271
name: cilium assembly
namespace: biological_process
alt_id: GO:0042384
def: "The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:BHF, GOC:cilia, GOC:dph, GOC:kmv, GOC:pr, GOC:vw, ISBN:0198506732, PMID:13978319, PMID:27350441, Reactome:R-HSA-5617833.2]
comment: Note that we deem cilium and microtubule-based flagellum to be equivalent.
synonym: "ciliogenesis" EXACT []
synonym: "cilium biogenesis" RELATED [GOC:mah]
synonym: "cilium formation" EXACT []
synonym: "cilium morphogenesis" RELATED []
synonym: "cilium organization" RELATED [GOC:dph]
synonym: "microtubule-based flagellum assembly" EXACT []
xref: Reactome:R-HSA-5617833.2
is_a: GO:0044782 ! cilium organization
is_a: GO:0070925 ! organelle assembly
is_a: GO:0120031 ! plasma membrane bounded cell projection assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0005929 ! cilium
relationship: has_part GO:0035082 ! axoneme assembly
relationship: has_part GO:0035735 ! intraciliary transport involved in cilium assembly
relationship: has_part GO:0061512 ! protein localization to cilium
relationship: has_part GO:0097712 ! vesicle targeting, trans-Golgi to periciliary membrane compartment
relationship: has_part GO:1905349 ! ciliary transition zone assembly
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: results_in_assembly_of GO:0005929 ! cilium
relationship: starts_with GO:0097711 ! ciliary basal body-plasma membrane docking
property_value: RO:0002161 NCBITaxon:3176
property_value: RO:0002161 NCBITaxon:3312
property_value: RO:0002161 NCBITaxon:3378
property_value: RO:0002161 NCBITaxon:3398
property_value: RO:0002161 NCBITaxon:4890
property_value: RO:0002161 NCBITaxon:5782

[Term]
id: GO:0060281
name: regulation of oocyte development
namespace: biological_process
def: "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb, PMID:2394318]
is_a: GO:1905879 ! regulation of oogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048599 ! oocyte development
relationship: regulates GO:0048599 ! oocyte development

[Term]
id: GO:0060282
name: positive regulation of oocyte development
namespace: biological_process
def: "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb]
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0060281 ! regulation of oocyte development
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048599 ! oocyte development
relationship: positively_regulates GO:0048599 ! oocyte development

[Term]
id: GO:0060283
name: negative regulation of oocyte development
namespace: biological_process
def: "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb]
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0060281 ! regulation of oocyte development
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048599 ! oocyte development
relationship: negatively_regulates GO:0048599 ! oocyte development

[Term]
id: GO:0060284
name: regulation of cell development
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph, GOC:tb]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048468 ! cell development
relationship: regulates GO:0048468 ! cell development

[Term]
id: GO:0060285
name: cilium-dependent cell motility
namespace: biological_process
alt_id: GO:0071974
def: "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:dgh, GOC:dph, GOC:krc, GOC:mlg, GOC:mtg_cambridge_2013]
comment: Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent.
synonym: "ciliary cell motility" RELATED []
synonym: "cilium cell motility" EXACT []
synonym: "microtubule-based flagellar cell motility" EXACT []
is_a: GO:0001539 ! cilium or flagellum-dependent cell motility
relationship: has_part GO:0003341 ! cilium movement

[Term]
id: GO:0060294
name: cilium movement involved in cell motility
namespace: biological_process
def: "Movement of cilia mediated by motor proteins that contributes to the movement of a cell." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0003341 ! cilium movement
intersection_of: GO:0003341 ! cilium movement
intersection_of: part_of GO:0048870 ! cell motility
relationship: part_of GO:0060285 ! cilium-dependent cell motility

[Term]
id: GO:0060295
name: regulation of cilium movement involved in cell motility
namespace: biological_process
def: "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0003352 ! regulation of cilium movement
is_a: GO:1902019 ! regulation of cilium-dependent cell motility
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060294 ! cilium movement involved in cell motility
relationship: regulates GO:0060294 ! cilium movement involved in cell motility

[Term]
id: GO:0060297
name: regulation of sarcomere organization
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "regulation of sarcomere organisation" EXACT [GOC:mah]
is_a: GO:0110020 ! regulation of actomyosin structure organization
is_a: GO:1902903 ! regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0045214 ! sarcomere organization
relationship: regulates GO:0045214 ! sarcomere organization

[Term]
id: GO:0060298
name: positive regulation of sarcomere organization
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "positive regulation of sarcomere organisation" EXACT [GOC:mah]
is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation
is_a: GO:0051495 ! positive regulation of cytoskeleton organization
is_a: GO:0060297 ! regulation of sarcomere organization
is_a: GO:1902905 ! positive regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0045214 ! sarcomere organization
relationship: positively_regulates GO:0045214 ! sarcomere organization

[Term]
id: GO:0060299
name: negative regulation of sarcomere organization
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb]
synonym: "negative regulation of sarcomere organisation" EXACT [GOC:mah]
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0051494 ! negative regulation of cytoskeleton organization
is_a: GO:0060297 ! regulation of sarcomere organization
is_a: GO:1902116 ! negative regulation of organelle assembly
is_a: GO:1902904 ! negative regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045214 ! sarcomere organization
relationship: negatively_regulates GO:0045214 ! sarcomere organization

[Term]
id: GO:0060322
name: head development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000033 ! head
relationship: results_in_development_of UBERON:0000033 ! head

[Term]
id: GO:0060323
name: head morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body." [GOC:dph]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000033 ! head
relationship: part_of GO:0010171 ! body morphogenesis
relationship: part_of GO:0060322 ! head development
relationship: results_in_morphogenesis_of UBERON:0000033 ! head

[Term]
id: GO:0060324
name: face development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head." [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001456 ! face
relationship: part_of GO:0060322 ! head development
relationship: results_in_development_of UBERON:0001456 ! face

[Term]
id: GO:0060325
name: face morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head." [GOC:dph]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001456 ! face
relationship: part_of GO:0060323 ! head morphogenesis
relationship: part_of GO:0060324 ! face development
relationship: results_in_morphogenesis_of UBERON:0001456 ! face

[Term]
id: GO:0060341
name: regulation of cellular localization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." [GOC:dph, GOC:tb]
synonym: "regulation of cellular localisation" EXACT [GOC:mah]
is_a: GO:0032879 ! regulation of localization
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051641 ! cellular localization
relationship: regulates GO:0051641 ! cellular localization

[Term]
id: GO:0060343
name: trabecula formation
namespace: biological_process
def: "The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph]
synonym: "trabecula biogenesis" RELATED [GOC:dph]
synonym: "trabeculation" EXACT [GOC:dph]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000440 ! trabecula
relationship: part_of GO:0009887 ! animal organ morphogenesis
relationship: part_of GO:0061383 ! trabecula morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0000440 ! trabecula

[Term]
id: GO:0060344
name: liver trabecula formation
namespace: biological_process
def: "The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph]
synonym: "liver trabecula biogenesis" RELATED []
synonym: "liver trabeculation" EXACT [GOC:dph]
is_a: GO:0060343 ! trabecula formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0010183 ! liver trabecula
relationship: part_of GO:0001889 ! liver development
relationship: results_in_formation_of_anatomical_entity UBERON:0010183 ! liver trabecula

[Term]
id: GO:0060345
name: spleen trabecula formation
namespace: biological_process
def: "The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph]
synonym: "spleen trabecula biogenesis" RELATED [GOC:dph]
synonym: "spleen trabeculation" EXACT [GOC:dph]
is_a: GO:0060343 ! trabecula formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001265 ! trabecula of spleen
relationship: part_of GO:0048536 ! spleen development
relationship: results_in_formation_of_anatomical_entity UBERON:0001265 ! trabecula of spleen

[Term]
id: GO:0060347
name: heart trabecula formation
namespace: biological_process
def: "The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph]
synonym: "cardiac trabecula formation" EXACT [GOC:dph]
synonym: "cardiac trabeculation" EXACT [GOC:dph]
synonym: "heart trabecula biogenesis" RELATED [GOC:dph]
synonym: "heart trabeculation" EXACT [GOC:dph]
is_a: GO:0060343 ! trabecula formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002511 ! trabecula carnea
relationship: part_of GO:0003206 ! cardiac chamber morphogenesis
relationship: part_of GO:0061384 ! heart trabecula morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002511 ! trabecula carnea

[Term]
id: GO:0060348
name: bone development
namespace: biological_process
def: "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components." [GOC:dph]
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048513 ! animal organ development
intersection_of: results_in_development_of UBERON:0001474 ! bone element
relationship: part_of GO:0001501 ! skeletal system development
relationship: results_in_development_of UBERON:0001474 ! bone element

[Term]
id: GO:0060349
name: bone morphogenesis
namespace: biological_process
def: "The process in which bones are generated and organized." [GOC:dph]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001474 ! bone element
relationship: part_of GO:0048705 ! skeletal system morphogenesis
relationship: part_of GO:0060348 ! bone development
relationship: results_in_morphogenesis_of UBERON:0001474 ! bone element

[Term]
id: GO:0060350
name: endochondral bone morphogenesis
namespace: biological_process
def: "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone." [GOC:dph, PMID:11680679]
is_a: GO:0060349 ! bone morphogenesis
intersection_of: GO:0060349 ! bone morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002513 ! endochondral bone
relationship: results_in_morphogenesis_of UBERON:0002513 ! endochondral bone

[Term]
id: GO:0060351
name: cartilage development involved in endochondral bone morphogenesis
namespace: biological_process
def: "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones." [GOC:dph]
is_a: GO:0051216 ! cartilage development
intersection_of: GO:0051216 ! cartilage development
intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis
relationship: part_of GO:0060350 ! endochondral bone morphogenesis

[Term]
id: GO:0060359
name: response to ammonium ion
namespace: biological_process
alt_id: GO:1903717
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23509267]
synonym: "response to ammonia" EXACT []
is_a: GO:0010035 ! response to inorganic substance
is_a: GO:1901698 ! response to nitrogen compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:28938 ! ammonium
relationship: has_primary_input CHEBI:28938 ! ammonium

[Term]
id: GO:0060379
name: cardiac muscle cell myoblast differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:dph, GOC:tb]
synonym: "cardiac myoblast differentiation" RELATED [GOC:dph, GOC:tb]
synonym: "myocardial precursor cell differentiation" EXACT [GOC:mtg_heart]
is_a: GO:0010002 ! cardioblast differentiation
is_a: GO:0045445 ! myoblast differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000513 ! cardiac muscle myoblast
relationship: results_in_acquisition_of_features_of CL:0000513 ! cardiac muscle myoblast

[Term]
id: GO:0060404
name: axonemal microtubule depolymerization
namespace: biological_process
def: "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." [GOC:cilia, GOC:dph, GOC:krc, GOC:tb]
is_a: GO:0010938 ! cytoplasmic microtubule depolymerization
is_a: GO:0061523 ! cilium disassembly
intersection_of: GO:0007019 ! microtubule depolymerization
intersection_of: occurs_in GO:0005930 ! axoneme
relationship: occurs_in GO:0005930 ! axoneme

[Term]
id: GO:0060408
name: regulation of acetylcholine metabolic process
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb]
is_a: GO:0033238 ! regulation of amine metabolic process
is_a: GO:0080090 ! regulation of primary metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008291 ! acetylcholine metabolic process
relationship: regulates GO:0008291 ! acetylcholine metabolic process

[Term]
id: GO:0060409
name: positive regulation of acetylcholine metabolic process
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb]
is_a: GO:0033240 ! positive regulation of amine metabolic process
is_a: GO:0060408 ! regulation of acetylcholine metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008291 ! acetylcholine metabolic process
relationship: positively_regulates GO:0008291 ! acetylcholine metabolic process

[Term]
id: GO:0060410
name: negative regulation of acetylcholine metabolic process
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb]
is_a: GO:0033239 ! negative regulation of amine metabolic process
is_a: GO:0060408 ! regulation of acetylcholine metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008291 ! acetylcholine metabolic process
relationship: negatively_regulates GO:0008291 ! acetylcholine metabolic process

[Term]
id: GO:0060411
name: cardiac septum morphogenesis
namespace: biological_process
alt_id: GO:0003280
def: "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart." [GOC:dph, GOC:mtg_heart]
synonym: "heart septum morphogenesis" EXACT []
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002099 ! cardiac septum
relationship: part_of GO:0003206 ! cardiac chamber morphogenesis
relationship: part_of GO:0003279 ! cardiac septum development
relationship: results_in_morphogenesis_of UBERON:0002099 ! cardiac septum

[Term]
id: GO:0060412
name: ventricular septum morphogenesis
namespace: biological_process
def: "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another." [GOC:dph]
synonym: "interventricular septum morphogenesis" EXACT [GOC:dph]
is_a: GO:0060411 ! cardiac septum morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002094 ! interventricular septum
relationship: part_of GO:0003281 ! ventricular septum development
relationship: results_in_morphogenesis_of UBERON:0002094 ! interventricular septum

[Term]
id: GO:0060413
name: atrial septum morphogenesis
namespace: biological_process
alt_id: GO:0003287
def: "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another." [GOC:dph, GOC:mtg_heart]
synonym: "interatrial septum morphogenesis" EXACT [GOC:dph]
is_a: GO:0060411 ! cardiac septum morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002085 ! interatrial septum
relationship: part_of GO:0003209 ! cardiac atrium morphogenesis
relationship: part_of GO:0003283 ! atrial septum development
relationship: results_in_morphogenesis_of UBERON:0002085 ! interatrial septum

[Term]
id: GO:0060414
name: aorta smooth muscle tissue morphogenesis
namespace: biological_process
def: "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, GOC:dph, Wikipedia:Aorta]
is_a: GO:0060415 ! muscle tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004178 ! aorta smooth muscle tissue
relationship: part_of GO:0035909 ! aorta morphogenesis
relationship: part_of GO:0048745 ! smooth muscle tissue development
relationship: results_in_morphogenesis_of UBERON:0004178 ! aorta smooth muscle tissue

[Term]
id: GO:0060415
name: muscle tissue morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function." [GOC:dph]
is_a: GO:0048729 ! tissue morphogenesis
intersection_of: GO:0048729 ! tissue morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002385 ! muscle tissue
relationship: part_of GO:0048644 ! muscle organ morphogenesis
relationship: results_in_morphogenesis_of UBERON:0002385 ! muscle tissue

[Term]
id: GO:0060419
name: heart growth
namespace: biological_process
def: "The increase in size or mass of the heart." [GOC:dph, GOC:tb]
is_a: GO:0035265 ! organ growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: results_in_growth_of UBERON:0000948 ! heart
relationship: part_of GO:0007507 ! heart development
relationship: results_in_growth_of UBERON:0000948 ! heart

[Term]
id: GO:0060420
name: regulation of heart growth
namespace: biological_process
def: "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:tb]
is_a: GO:0046620 ! regulation of organ growth
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060419 ! heart growth
relationship: regulates GO:0060419 ! heart growth

[Term]
id: GO:0060421
name: positive regulation of heart growth
namespace: biological_process
def: "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:BHF, GOC:dph, GOC:tb]
is_a: GO:0046622 ! positive regulation of organ growth
is_a: GO:0060420 ! regulation of heart growth
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060419 ! heart growth
relationship: positively_regulates GO:0060419 ! heart growth

[Term]
id: GO:0060425
name: lung morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the lung are generated and organized." [GOC:dph]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002048 ! lung
relationship: part_of GO:0030324 ! lung development
relationship: results_in_morphogenesis_of UBERON:0002048 ! lung

[Term]
id: GO:0060426
name: lung vasculature development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs." [GOC:dph, GOC:mtg_lung]
synonym: "pulmonary vasculature development" EXACT [GOC:dph, GOC:mtg_lung]
is_a: GO:0001944 ! vasculature development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000102 ! lung vasculature
relationship: part_of GO:0030324 ! lung development
relationship: results_in_development_of UBERON:0000102 ! lung vasculature

[Term]
id: GO:0060427
name: lung connective tissue development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs." [GOC:dph, GOC:mtg_lung]
synonym: "pulmonary connective tissue development" EXACT []
is_a: GO:0061448 ! connective tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000114 ! lung connective tissue
relationship: part_of GO:0030324 ! lung development
relationship: results_in_development_of UBERON:0000114 ! lung connective tissue

[Term]
id: GO:0060428
name: lung epithelium development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung." [GOC:dph, GOC:mtg_lung]
synonym: "pulmonary epithelium development" EXACT [GOC:dph, GOC:mtg_lung]
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000115 ! lung epithelium
relationship: part_of GO:0030324 ! lung development
relationship: results_in_development_of UBERON:0000115 ! lung epithelium

[Term]
id: GO:0060429
name: epithelium development
namespace: biological_process
def: "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:dph, GOC:mtg_lung]
subset: goslim_drosophila
is_a: GO:0009888 ! tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000483 ! epithelium
relationship: results_in_development_of UBERON:0000483 ! epithelium

[Term]
id: GO:0060431
name: primary lung bud formation
namespace: biological_process
def: "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds." [GOC:dph, GOC:mtg_lung]
synonym: "lung formation" EXACT [GOC:dph]
is_a: GO:0016331 ! morphogenesis of embryonic epithelium
is_a: GO:0048645 ! animal organ formation
is_a: GO:0060441 ! epithelial tube branching involved in lung morphogenesis
is_a: GO:0060572 ! morphogenesis of an epithelial bud
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002048 ! lung
relationship: results_in_formation_of_anatomical_entity UBERON:0002048 ! lung

[Term]
id: GO:0060437
name: lung growth
namespace: biological_process
def: "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:dph]
is_a: GO:0035265 ! organ growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: results_in_growth_of UBERON:0002048 ! lung
relationship: part_of GO:0030324 ! lung development
relationship: results_in_growth_of UBERON:0002048 ! lung

[Term]
id: GO:0060438
name: trachea development
namespace: biological_process
def: "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph]
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001005 ! respiratory airway
relationship: part_of GO:0060541 ! respiratory system development
relationship: results_in_development_of UBERON:0001005 ! respiratory airway

[Term]
id: GO:0060439
name: trachea morphogenesis
namespace: biological_process
def: "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001005 ! respiratory airway
relationship: part_of GO:0060438 ! trachea development
relationship: results_in_morphogenesis_of UBERON:0001005 ! respiratory airway

[Term]
id: GO:0060440
name: trachea formation
namespace: biological_process
def: "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph]
is_a: GO:0048645 ! animal organ formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001005 ! respiratory airway
relationship: part_of GO:0060439 ! trachea morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001005 ! respiratory airway

[Term]
id: GO:0060441
name: epithelial tube branching involved in lung morphogenesis
namespace: biological_process
def: "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:mtg_lung]
synonym: "lung branching morphogenesis" EXACT [GOC:dph]
is_a: GO:0048754 ! branching morphogenesis of an epithelial tube
intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube
intersection_of: part_of GO:0060425 ! lung morphogenesis
relationship: part_of GO:0060425 ! lung morphogenesis

[Term]
id: GO:0060450
name: positive regulation of hindgut contraction
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb]
is_a: GO:0043134 ! regulation of hindgut contraction
is_a: GO:0045987 ! positive regulation of smooth muscle contraction
is_a: GO:0060456 ! positive regulation of digestive system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0043133 ! hindgut contraction
relationship: positively_regulates GO:0043133 ! hindgut contraction

[Term]
id: GO:0060451
name: negative regulation of hindgut contraction
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb]
is_a: GO:0043134 ! regulation of hindgut contraction
is_a: GO:0045986 ! negative regulation of smooth muscle contraction
is_a: GO:0060457 ! negative regulation of digestive system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0043133 ! hindgut contraction
relationship: negatively_regulates GO:0043133 ! hindgut contraction

[Term]
id: GO:0060452
name: positive regulation of cardiac muscle contraction
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of cardiac muscle contraction." [GOC:dph, GOC:tb]
is_a: GO:0045823 ! positive regulation of heart contraction
is_a: GO:0045989 ! positive regulation of striated muscle contraction
is_a: GO:0055117 ! regulation of cardiac muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060048 ! cardiac muscle contraction
relationship: positively_regulates GO:0060048 ! cardiac muscle contraction

[Term]
id: GO:0060453
name: regulation of gastric acid secretion
namespace: biological_process
def: "Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb]
is_a: GO:0044058 ! regulation of digestive system process
is_a: GO:0051046 ! regulation of secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001696 ! gastric acid secretion
relationship: regulates GO:0001696 ! gastric acid secretion

[Term]
id: GO:0060454
name: positive regulation of gastric acid secretion
namespace: biological_process
def: "Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb]
is_a: GO:0051047 ! positive regulation of secretion
is_a: GO:0060453 ! regulation of gastric acid secretion
is_a: GO:0060456 ! positive regulation of digestive system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001696 ! gastric acid secretion
relationship: positively_regulates GO:0001696 ! gastric acid secretion

[Term]
id: GO:0060455
name: negative regulation of gastric acid secretion
namespace: biological_process
def: "Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb]
is_a: GO:0051048 ! negative regulation of secretion
is_a: GO:0060453 ! regulation of gastric acid secretion
is_a: GO:0060457 ! negative regulation of digestive system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001696 ! gastric acid secretion
relationship: negatively_regulates GO:0001696 ! gastric acid secretion

[Term]
id: GO:0060456
name: positive regulation of digestive system process
namespace: biological_process
def: "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb]
is_a: GO:0044058 ! regulation of digestive system process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0022600 ! digestive system process
relationship: positively_regulates GO:0022600 ! digestive system process

[Term]
id: GO:0060457
name: negative regulation of digestive system process
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb]
is_a: GO:0044058 ! regulation of digestive system process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0022600 ! digestive system process
relationship: negatively_regulates GO:0022600 ! digestive system process

[Term]
id: GO:0060458
name: right lung development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung]
synonym: "right pulmonary development" EXACT [GOC:dph, GOC:mtg_lung]
is_a: GO:0030324 ! lung development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002167 ! right lung
relationship: results_in_development_of UBERON:0002167 ! right lung

[Term]
id: GO:0060459
name: left lung development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung]
synonym: "left pulmonary development" EXACT [GOC:dph]
is_a: GO:0030324 ! lung development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002168 ! left lung
relationship: results_in_development_of UBERON:0002168 ! left lung

[Term]
id: GO:0060460
name: left lung morphogenesis
namespace: biological_process
def: "The process in which anatomical structures of the left lung are generated and organized." [GOC:dph]
is_a: GO:0060425 ! lung morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002168 ! left lung
relationship: part_of GO:0060459 ! left lung development
relationship: results_in_morphogenesis_of UBERON:0002168 ! left lung

[Term]
id: GO:0060461
name: right lung morphogenesis
namespace: biological_process
def: "The process in which anatomical structures of the right lung are generated and organized." [GOC:dph, GOC:mtg_lung]
is_a: GO:0060425 ! lung morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002167 ! right lung
relationship: part_of GO:0060458 ! right lung development
relationship: results_in_morphogenesis_of UBERON:0002167 ! right lung

[Term]
id: GO:0060462
name: lung lobe development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung." [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000101 ! lobe of lung
relationship: part_of GO:0030324 ! lung development
relationship: results_in_development_of UBERON:0000101 ! lobe of lung

[Term]
id: GO:0060463
name: lung lobe morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung." [GOC:dph]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000101 ! lobe of lung
relationship: part_of GO:0060425 ! lung morphogenesis
relationship: part_of GO:0060462 ! lung lobe development
relationship: results_in_morphogenesis_of UBERON:0000101 ! lobe of lung

[Term]
id: GO:0060464
name: lung lobe formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung." [GOC:dph]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000101 ! lobe of lung
relationship: part_of GO:0060463 ! lung lobe morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0000101 ! lobe of lung

[Term]
id: GO:0060465
name: pharynx development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." [GOC:dph, GOC:rk]
synonym: "pharyngeal development" RELATED []
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0006562 ! pharynx
relationship: part_of GO:0048565 ! digestive tract development
relationship: results_in_development_of UBERON:0006562 ! pharynx

[Term]
id: GO:0060467
name: negative regulation of fertilization
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:dph]
is_a: GO:0080154 ! regulation of fertilization
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009566 ! fertilization
relationship: negatively_regulates GO:0009566 ! fertilization

[Term]
id: GO:0060468
name: prevention of polyspermy
namespace: biological_process
def: "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg." [GOC:dph]
synonym: "negative regulation of fertilization involved in egg activation" EXACT [GOC:dph]
synonym: "polyspermy block" EXACT [GOC:dph]
is_a: GO:0022414 ! reproductive process
is_a: GO:0060467 ! negative regulation of fertilization
intersection_of: GO:0060467 ! negative regulation of fertilization
intersection_of: part_of GO:0007343 ! egg activation
relationship: part_of GO:0007343 ! egg activation

[Term]
id: GO:0060474
name: positive regulation of flagellated sperm motility involved in capacitation
namespace: biological_process
def: "The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence." [GOC:cilia, GOC:dph, GOC:krc]
synonym: "positive regulation of sperm motility involved in capacitation" RELATED []
is_a: GO:0022414 ! reproductive process
is_a: GO:1902093 ! positive regulation of flagellated sperm motility
intersection_of: GO:1902093 ! positive regulation of flagellated sperm motility
intersection_of: part_of GO:0048240 ! sperm capacitation
relationship: part_of GO:0048240 ! sperm capacitation

[Term]
id: GO:0060479
name: lung cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:mtg_lung]
synonym: "pulmonary cell differentiation" EXACT [GOC:dph]
is_a: GO:0030154 ! cell differentiation
relationship: part_of GO:0030324 ! lung development

[Term]
id: GO:0060485
name: mesenchyme development
namespace: biological_process
def: "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:dph]
synonym: "mesenchymal development" EXACT [GOC:dph]
is_a: GO:0009888 ! tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003104 ! mesenchyme
relationship: part_of GO:0048513 ! animal organ development
relationship: results_in_development_of UBERON:0003104 ! mesenchyme

[Term]
id: GO:0060487
name: lung epithelial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung." [GOC:dph]
synonym: "pulmonary epithelial cell differentiation" RELATED [GOC:dph]
is_a: GO:0030855 ! epithelial cell differentiation
is_a: GO:0060479 ! lung cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000082 ! epithelial cell of lung
relationship: part_of GO:0060428 ! lung epithelium development
relationship: results_in_acquisition_of_features_of CL:0000082 ! epithelial cell of lung

[Term]
id: GO:0060491
name: regulation of cell projection assembly
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of cell projection assembly." [GOC:dph, GOC:tb]
synonym: "regulation of cell projection formation" RELATED [GOC:dph, GOC:tb]
is_a: GO:0031344 ! regulation of cell projection organization
is_a: GO:0044087 ! regulation of cellular component biogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030031 ! cell projection assembly
relationship: regulates GO:0030031 ! cell projection assembly

[Term]
id: GO:0060495
name: cell-cell signaling involved in lung development
namespace: biological_process
def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure." [GOC:dph, GOC:mtg_lung]
synonym: "cell-cell signalling involved in lung development" EXACT [GOC:mah]
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: part_of GO:0030324 ! lung development
relationship: part_of GO:0030324 ! lung development

[Term]
id: GO:0060496
name: mesenchymal-epithelial cell signaling involved in lung development
namespace: biological_process
def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung." [GOC:dph, GOC:mtg_lung]
synonym: "mesenchymal-epithelial cell signalling involved in lung development" EXACT [GOC:mah]
is_a: GO:0060495 ! cell-cell signaling involved in lung development
is_a: GO:0060638 ! mesenchymal-epithelial cell signaling
intersection_of: GO:0060638 ! mesenchymal-epithelial cell signaling
intersection_of: part_of GO:0030324 ! lung development

[Term]
id: GO:0060497
name: mesenchymal-endodermal cell signaling
namespace: biological_process
def: "Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell." [GOC:dph]
synonym: "mesenchymal-endodermal cell signalling" EXACT [GOC:mah]
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: has_end_location CL:0000223 ! endodermal cell
intersection_of: has_start_location CL:0008019 ! mesenchymal cell
relationship: has_end_location CL:0000223 ! endodermal cell
relationship: has_start_location CL:0008019 ! mesenchymal cell

[Term]
id: GO:0060501
name: positive regulation of epithelial cell proliferation involved in lung morphogenesis
namespace: biological_process
def: "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape." [GOC:dph]
is_a: GO:0050679 ! positive regulation of epithelial cell proliferation
is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis
relationship: positively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis

[Term]
id: GO:0060502
name: epithelial cell proliferation involved in lung morphogenesis
namespace: biological_process
def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung." [GOC:dph]
is_a: GO:0050673 ! epithelial cell proliferation
intersection_of: GO:0050673 ! epithelial cell proliferation
intersection_of: part_of GO:0060425 ! lung morphogenesis
relationship: part_of GO:0060425 ! lung morphogenesis
relationship: part_of GO:0060428 ! lung epithelium development

[Term]
id: GO:0060536
name: cartilage morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of cartilage are generated and organized." [GOC:dph]
is_a: GO:0009887 ! animal organ morphogenesis
is_a: GO:0048729 ! tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0007844 ! cartilage element
relationship: part_of GO:0051216 ! cartilage development
relationship: results_in_morphogenesis_of UBERON:0007844 ! cartilage element
created_by: dph
creation_date: 2009-04-10T09:13:27Z

[Term]
id: GO:0060537
name: muscle tissue development
namespace: biological_process
def: "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers." [GOC:dph]
is_a: GO:0009888 ! tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002385 ! muscle tissue
relationship: results_in_development_of UBERON:0002385 ! muscle tissue
created_by: dph
creation_date: 2009-04-10T08:05:37Z

[Term]
id: GO:0060538
name: skeletal muscle organ development
namespace: biological_process
def: "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." [GOC:dph]
is_a: GO:0007517 ! muscle organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0014892 ! skeletal muscle organ, vertebrate
relationship: results_in_development_of UBERON:0014892 ! skeletal muscle organ, vertebrate
created_by: dph
creation_date: 2009-04-10T08:25:12Z

[Term]
id: GO:0060539
name: diaphragm development
namespace: biological_process
def: "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs." [GOC:dph]
is_a: GO:0060538 ! skeletal muscle organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001103 ! diaphragm
relationship: part_of GO:0060541 ! respiratory system development
relationship: results_in_development_of UBERON:0001103 ! diaphragm
property_value: RO:0002161 NCBITaxon:8782
created_by: dph
creation_date: 2009-04-10T08:44:56Z

[Term]
id: GO:0060540
name: diaphragm morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the diaphragm are generated and organized." [GOC:dph]
is_a: GO:0048644 ! muscle organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001103 ! diaphragm
relationship: part_of GO:0060539 ! diaphragm development
relationship: results_in_morphogenesis_of UBERON:0001103 ! diaphragm
property_value: RO:0002161 NCBITaxon:8782
created_by: dph
creation_date: 2009-04-10T08:47:51Z

[Term]
id: GO:0060541
name: respiratory system development
namespace: biological_process
def: "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange." [GOC:dph]
subset: goslim_drosophila
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001004 ! respiratory system
relationship: results_in_development_of UBERON:0001004 ! respiratory system
created_by: dph
creation_date: 2009-04-10T08:55:42Z

[Term]
id: GO:0060560
name: developmental growth involved in morphogenesis
namespace: biological_process
def: "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." [GOC:dph]
synonym: "differential growth" EXACT [GOC:dph]
is_a: GO:0048589 ! developmental growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis
relationship: part_of GO:0009653 ! anatomical structure morphogenesis
created_by: dph
creation_date: 2009-04-28T08:42:53Z

[Term]
id: GO:0060561
name: apoptotic process involved in morphogenesis
namespace: biological_process
def: "Any apoptotic process that contributes to the shaping of an anatomical structure." [GOC:dph, GOC:mtg_apoptosis]
synonym: "apoptosis involved in development" RELATED []
synonym: "apoptosis involved in morphogenesis" NARROW []
synonym: "morphogenetic apoptosis" RELATED [GOC:dph]
is_a: GO:1902742 ! apoptotic process involved in development
intersection_of: GO:0006915 ! apoptotic process
intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis
relationship: part_of GO:0009653 ! anatomical structure morphogenesis
created_by: dph
creation_date: 2009-04-28T09:17:27Z

[Term]
id: GO:0060562
name: epithelial tube morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:dph]
is_a: GO:0002009 ! morphogenesis of an epithelium
is_a: GO:0035239 ! tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003914 ! epithelial tube
relationship: results_in_morphogenesis_of UBERON:0003914 ! epithelial tube
created_by: dph
creation_date: 2009-04-28T09:33:36Z

[Term]
id: GO:0060563
name: neuroepithelial cell differentiation
namespace: biological_process
def: "The process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, GOC:tb]
is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000710 ! neurecto-epithelial cell
relationship: results_in_acquisition_of_features_of CL:0000710 ! neurecto-epithelial cell
created_by: dph
creation_date: 2009-04-29T01:50:05Z

[Term]
id: GO:0060571
name: morphogenesis of an epithelial fold
namespace: biological_process
def: "The morphogenetic process in which an epithelial sheet bends along a linear axis." [GOC:dph]
synonym: "epithelial folding" EXACT [GOC:dph]
synonym: "folding of an epithelial sheet" RELATED [GOC:dph]
is_a: GO:0002009 ! morphogenesis of an epithelium
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005157 ! epithelial fold
relationship: results_in_morphogenesis_of UBERON:0005157 ! epithelial fold
created_by: dph
creation_date: 2009-04-30T09:27:17Z

[Term]
id: GO:0060572
name: morphogenesis of an epithelial bud
namespace: biological_process
def: "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding." [GOC:dph]
is_a: GO:0060571 ! morphogenesis of an epithelial fold
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005153 ! epithelial bud
relationship: results_in_morphogenesis_of UBERON:0005153 ! epithelial bud
created_by: dph
creation_date: 2009-04-30T09:38:35Z

[Term]
id: GO:0060574
name: intestinal epithelial cell maturation
namespace: biological_process
def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus." [GOC:dph, PMID:18824147]
is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0002563 ! intestinal epithelial cell
relationship: part_of GO:0060576 ! intestinal epithelial cell development
relationship: results_in_maturation_of CL:0002563 ! intestinal epithelial cell
created_by: dph
creation_date: 2009-05-06T08:10:41Z

[Term]
id: GO:0060575
name: intestinal epithelial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine." [GOC:dph]
is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002563 ! intestinal epithelial cell
relationship: part_of GO:0048565 ! digestive tract development
relationship: results_in_acquisition_of_features_of CL:0002563 ! intestinal epithelial cell
created_by: dph
creation_date: 2009-05-06T08:17:56Z

[Term]
id: GO:0060576
name: intestinal epithelial cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure." [GOC:dph]
is_a: GO:0002066 ! columnar/cuboidal epithelial cell development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of CL:0002563 ! intestinal epithelial cell
relationship: part_of GO:0060575 ! intestinal epithelial cell differentiation
relationship: results_in_development_of CL:0002563 ! intestinal epithelial cell
created_by: dph
creation_date: 2009-05-06T08:20:24Z

[Term]
id: GO:0060577
name: pulmonary vein morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart." [GOC:dph]
synonym: "pulmonary venous blood vessel morphogenesis" RELATED [GOC:dph]
is_a: GO:0048845 ! venous blood vessel morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002016 ! pulmonary vein
relationship: results_in_morphogenesis_of UBERON:0002016 ! pulmonary vein
created_by: dph
creation_date: 2009-05-06T08:44:04Z

[Term]
id: GO:0060578
name: superior vena cava morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart." [GOC:dph]
is_a: GO:0048845 ! venous blood vessel morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001585 ! anterior vena cava
relationship: results_in_morphogenesis_of UBERON:0001585 ! anterior vena cava
created_by: dph
creation_date: 2009-05-06T08:47:21Z

[Term]
id: GO:0060581
name: cell fate commitment involved in pattern specification
namespace: biological_process
def: "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type." [GOC:dph]
is_a: GO:0045165 ! cell fate commitment
intersection_of: GO:0045165 ! cell fate commitment
intersection_of: part_of GO:0007389 ! pattern specification process
relationship: part_of GO:0007389 ! pattern specification process
created_by: dph
creation_date: 2009-05-07T12:40:55Z

[Term]
id: GO:0060591
name: chondroblast differentiation
namespace: biological_process
def: "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes." [GOC:dph]
synonym: "chondrocyte progenitor cell differentiation" RELATED [GOC:dph]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000058 ! chondroblast
relationship: part_of GO:0051216 ! cartilage development
relationship: results_in_acquisition_of_features_of CL:0000058 ! chondroblast
created_by: dph
creation_date: 2009-05-11T07:47:36Z

[Term]
id: GO:0060612
name: adipose tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat." [GOC:dph]
synonym: "adipogenesis" RELATED [GOC:mah, GOC:sl]
is_a: GO:0061448 ! connective tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001013 ! adipose tissue
relationship: part_of GO:0048513 ! animal organ development
relationship: results_in_development_of UBERON:0001013 ! adipose tissue
created_by: dph
creation_date: 2009-05-15T12:36:28Z

[Term]
id: GO:0060623
name: regulation of chromosome condensation
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:dph, GOC:tb]
is_a: GO:0033044 ! regulation of chromosome organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030261 ! chromosome condensation
relationship: regulates GO:0030261 ! chromosome condensation
created_by: dph
creation_date: 2009-05-18T02:12:13Z

[Term]
id: GO:0060627
name: regulation of vesicle-mediated transport
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." [GOC:dph, GOC:tb]
is_a: GO:0050794 ! regulation of cellular process
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0016192 ! vesicle-mediated transport
relationship: regulates GO:0016192 ! vesicle-mediated transport
created_by: dph
creation_date: 2009-05-18T02:29:43Z

[Term]
id: GO:0060632
name: regulation of microtubule-based movement
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." [GOC:dph, GOC:tb]
is_a: GO:0032886 ! regulation of microtubule-based process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007018 ! microtubule-based movement
relationship: regulates GO:0007018 ! microtubule-based movement
created_by: dph
creation_date: 2009-05-18T03:07:02Z

[Term]
id: GO:0060638
name: mesenchymal-epithelial cell signaling
namespace: biological_process
def: "Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted." [GOC:dph]
synonym: "mesenchymal-epithelial cell signalling" EXACT [GOC:mah]
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: has_end_location CL:0000066 ! epithelial cell
intersection_of: has_start_location CL:0008019 ! mesenchymal cell
relationship: has_end_location CL:0000066 ! epithelial cell
relationship: has_start_location CL:0008019 ! mesenchymal cell
created_by: dph
creation_date: 2009-05-19T03:59:05Z

[Term]
id: GO:0060669
name: embryonic placenta morphogenesis
namespace: biological_process
def: "The process in which the embryonic placenta is generated and organized." [GOC:dph]
is_a: GO:0048598 ! embryonic morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0007106 ! chorionic villus
relationship: part_of GO:0001892 ! embryonic placenta development
relationship: results_in_morphogenesis_of UBERON:0007106 ! chorionic villus
created_by: dph
creation_date: 2009-06-02T09:33:37Z

[Term]
id: GO:0060670
name: branching involved in labyrinthine layer morphogenesis
namespace: biological_process
def: "The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer." [GOC:dph, PMID:16916377]
is_a: GO:0048598 ! embryonic morphogenesis
is_a: GO:0061138 ! morphogenesis of a branching epithelium
intersection_of: GO:0061138 ! morphogenesis of a branching epithelium
intersection_of: part_of GO:0060713 ! labyrinthine layer morphogenesis
relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis
created_by: dph
creation_date: 2009-06-02T10:40:40Z

[Term]
id: GO:0060671
name: epithelial cell differentiation involved in embryonic placenta development
namespace: biological_process
def: "The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer." [GOC:dph, PMID:16916377]
is_a: GO:0030855 ! epithelial cell differentiation
is_a: GO:0060706 ! cell differentiation involved in embryonic placenta development
intersection_of: GO:0030855 ! epithelial cell differentiation
intersection_of: part_of GO:0001892 ! embryonic placenta development
relationship: part_of GO:0060711 ! labyrinthine layer development
created_by: dph
creation_date: 2009-06-02T11:40:52Z

[Term]
id: GO:0060673
name: cell-cell signaling involved in placenta development
namespace: biological_process
def: "Any process that mediates the transfer of information from one cell to another." [GOC:dph, PMID:16916377]
synonym: "cell-cell signalling involved in placenta development" EXACT [GOC:mah]
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: part_of GO:0001890 ! placenta development
relationship: part_of GO:0001892 ! embryonic placenta development
created_by: dph
creation_date: 2009-06-02T12:58:03Z

[Term]
id: GO:0060674
name: placenta blood vessel development
namespace: biological_process
def: "The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure." [GOC:dph, PMID:16916377]
is_a: GO:0001568 ! blood vessel development
relationship: part_of GO:0001890 ! placenta development
created_by: dph
creation_date: 2009-06-02T01:09:43Z

[Term]
id: GO:0060675
name: ureteric bud morphogenesis
namespace: biological_process
def: "The process in which the ureteric bud is generated and organized." [GOC:dph, GOC:mtg_kidney_jan10]
is_a: GO:0072171 ! mesonephric tubule morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000084 ! ureteric bud
relationship: part_of GO:0001657 ! ureteric bud development
relationship: results_in_morphogenesis_of UBERON:0000084 ! ureteric bud
created_by: dph
creation_date: 2009-06-02T01:31:41Z

[Term]
id: GO:0060676
name: ureteric bud formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud." [GOC:dph, PMID:16916378]
is_a: GO:0072172 ! mesonephric tubule formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000084 ! ureteric bud
relationship: part_of GO:0060675 ! ureteric bud morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0000084 ! ureteric bud
created_by: dph
creation_date: 2009-06-02T01:47:23Z

[Term]
id: GO:0060684
name: epithelial-mesenchymal cell signaling
namespace: biological_process
def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted." [GOC:dph]
synonym: "epithelial-mesenchymal cell signalling" EXACT [GOC:mah]
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: has_end_location CL:0008019 ! mesenchymal cell
intersection_of: has_start_location CL:0000066 ! epithelial cell
relationship: has_end_location CL:0008019 ! mesenchymal cell
relationship: has_start_location CL:0000066 ! epithelial cell
created_by: dph
creation_date: 2009-06-03T06:36:46Z

[Term]
id: GO:0060688
name: regulation of morphogenesis of a branching structure
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized." [GOC:dph]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001763 ! morphogenesis of a branching structure
relationship: regulates GO:0001763 ! morphogenesis of a branching structure
created_by: dph
creation_date: 2009-06-05T12:41:44Z

[Term]
id: GO:0060706
name: cell differentiation involved in embryonic placenta development
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta." [GOC:dph]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: part_of GO:0001892 ! embryonic placenta development
relationship: part_of GO:0001892 ! embryonic placenta development
created_by: dph
creation_date: 2009-06-09T10:26:42Z

[Term]
id: GO:0060711
name: labyrinthine layer development
namespace: biological_process
def: "The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state." [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003946 ! placenta labyrinth
relationship: part_of GO:0001892 ! embryonic placenta development
relationship: results_in_development_of UBERON:0003946 ! placenta labyrinth
created_by: dph
creation_date: 2009-06-09T03:27:43Z

[Term]
id: GO:0060713
name: labyrinthine layer morphogenesis
namespace: biological_process
def: "The process in which the labyrinthine layer of the placenta is generated and organized." [GOC:dph]
is_a: GO:0048598 ! embryonic morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003946 ! placenta labyrinth
relationship: part_of GO:0060669 ! embryonic placenta morphogenesis
relationship: part_of GO:0060711 ! labyrinthine layer development
relationship: results_in_morphogenesis_of UBERON:0003946 ! placenta labyrinth
created_by: dph
creation_date: 2009-06-10T08:10:19Z

[Term]
id: GO:0060714
name: labyrinthine layer formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta." [GOC:dph]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003946 ! placenta labyrinth
relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0003946 ! placenta labyrinth
created_by: dph
creation_date: 2009-06-10T08:13:14Z

[Term]
id: GO:0060716
name: labyrinthine layer blood vessel development
namespace: biological_process
def: "The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." [GOC:dph]
is_a: GO:0048568 ! embryonic organ development
is_a: GO:0060674 ! placenta blood vessel development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004183 ! placental labyrinth blood vessel
relationship: part_of GO:0060711 ! labyrinthine layer development
relationship: results_in_development_of UBERON:0004183 ! placental labyrinth blood vessel
created_by: dph
creation_date: 2009-06-11T09:04:38Z

[Term]
id: GO:0060717
name: chorion development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane." [GOC:dph]
is_a: GO:1903867 ! extraembryonic membrane development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003124 ! chorion membrane
relationship: results_in_development_of UBERON:0003124 ! chorion membrane
created_by: dph
creation_date: 2009-06-11T02:37:50Z

[Term]
id: GO:0060718
name: chorionic trophoblast cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [CL:0011101, GOC:dph, PMID:16983341]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0011101 ! chorionic trophoblast cell
relationship: part_of GO:0060717 ! chorion development
relationship: results_in_acquisition_of_features_of CL:0011101 ! chorionic trophoblast cell
created_by: dph
creation_date: 2009-06-11T02:48:27Z

[Term]
id: GO:0060719
name: chorionic trophoblast cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [CL:0011101, GOC:16983341, GOC:dph]
is_a: GO:0048468 ! cell development
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:0011101 ! chorionic trophoblast cell
relationship: part_of GO:0060718 ! chorionic trophoblast cell differentiation
relationship: results_in_development_of CL:0011101 ! chorionic trophoblast cell
created_by: dph
creation_date: 2009-06-11T02:58:45Z

[Term]
id: GO:0060722
name: cell proliferation involved in embryonic placenta development
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta." [GOC:dph]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: part_of GO:0001892 ! embryonic placenta development
relationship: part_of GO:0001892 ! embryonic placenta development
created_by: dph
creation_date: 2009-06-12T12:46:04Z

[Term]
id: GO:0060723
name: regulation of cell proliferation involved in embryonic placenta development
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development." [GOC:dph]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060722 ! cell proliferation involved in embryonic placenta development
relationship: regulates GO:0060722 ! cell proliferation involved in embryonic placenta development
created_by: dph
creation_date: 2009-06-12T12:50:23Z

[Term]
id: GO:0060788
name: ectodermal placode formation
namespace: biological_process
def: "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005085 ! ectodermal placode
relationship: part_of GO:0071697 ! ectodermal placode morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0005085 ! ectodermal placode
created_by: dph
creation_date: 2009-08-04T12:15:57Z

[Term]
id: GO:0060795
name: cell fate commitment involved in formation of primary germ layer
namespace: biological_process
def: "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0045165 ! cell fate commitment
intersection_of: GO:0045165 ! cell fate commitment
intersection_of: part_of GO:0001704 ! formation of primary germ layer
relationship: part_of GO:0001704 ! formation of primary germ layer
created_by: dph
creation_date: 2009-08-04T03:11:22Z

[Term]
id: GO:0060800
name: regulation of cell differentiation involved in embryonic placenta development
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0045595 ! regulation of cell differentiation
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060706 ! cell differentiation involved in embryonic placenta development
relationship: regulates GO:0060706 ! cell differentiation involved in embryonic placenta development
created_by: dph
creation_date: 2009-08-06T01:20:25Z

[Term]
id: GO:0060806
name: negative regulation of cell differentiation involved in embryonic placenta development
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0060800 ! regulation of cell differentiation involved in embryonic placenta development
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060706 ! cell differentiation involved in embryonic placenta development
relationship: negatively_regulates GO:0060706 ! cell differentiation involved in embryonic placenta development
created_by: dph
creation_date: 2009-08-06T02:02:18Z

[Term]
id: GO:0060815
name: regulation of translation involved in anterior/posterior axis specification
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0006417 ! regulation of translation
intersection_of: GO:0006417 ! regulation of translation
intersection_of: part_of GO:0009948 ! anterior/posterior axis specification
relationship: part_of GO:0009948 ! anterior/posterior axis specification
created_by: dph
creation_date: 2009-08-07T10:02:31Z

[Term]
id: GO:0060837
name: blood vessel endothelial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0045446 ! endothelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000071 ! blood vessel endothelial cell
relationship: part_of GO:0001568 ! blood vessel development
relationship: results_in_acquisition_of_features_of CL:0000071 ! blood vessel endothelial cell
created_by: dph
creation_date: 2009-08-11T03:47:36Z

[Term]
id: GO:0060840
name: artery development
namespace: biological_process
def: "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0001568 ! blood vessel development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001637 ! artery
relationship: results_in_development_of UBERON:0001637 ! artery
created_by: dph
creation_date: 2009-08-12T10:10:51Z

[Term]
id: GO:0060841
name: venous blood vessel development
namespace: biological_process
def: "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0001568 ! blood vessel development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001638 ! vein
relationship: results_in_development_of UBERON:0001638 ! vein
created_by: dph
creation_date: 2009-08-12T10:14:07Z

[Term]
id: GO:0060842
name: arterial endothelial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0060837 ! blood vessel endothelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000413 ! endothelial cell of artery
relationship: results_in_acquisition_of_features_of CL:1000413 ! endothelial cell of artery
created_by: dph
creation_date: 2009-08-12T10:41:34Z

[Term]
id: GO:0060843
name: venous endothelial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0060837 ! blood vessel endothelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002543 ! vein endothelial cell
relationship: results_in_acquisition_of_features_of CL:0002543 ! vein endothelial cell
created_by: dph
creation_date: 2009-08-12T10:43:40Z

[Term]
id: GO:0060896
name: neural plate pattern specification
namespace: biological_process
def: "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0007389 ! pattern specification process
created_by: dph
creation_date: 2009-08-13T02:06:27Z

[Term]
id: GO:0060897
name: neural plate regionalization
namespace: biological_process
def: "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0003002 ! regionalization
is_a: GO:0060896 ! neural plate pattern specification
created_by: dph
creation_date: 2009-08-13T02:09:04Z

[Term]
id: GO:0060900
name: embryonic camera-type eye formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
relationship: part_of GO:0048596 ! embryonic camera-type eye morphogenesis
created_by: dph
creation_date: 2009-08-13T02:26:54Z

[Term]
id: GO:0060914
name: heart formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable." [GOC:mtg_heart]
synonym: "cardiogenesis" RELATED [GOC:mtg_heart]
is_a: GO:0048645 ! animal organ formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000948 ! heart
relationship: part_of GO:0003007 ! heart morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0000948 ! heart
created_by: dph
creation_date: 2009-09-17T09:02:13Z

[Term]
id: GO:0060915
name: mesenchymal cell differentiation involved in lung development
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph]
is_a: GO:0048762 ! mesenchymal cell differentiation
intersection_of: GO:0048762 ! mesenchymal cell differentiation
intersection_of: part_of GO:0030324 ! lung development
relationship: part_of GO:0030324 ! lung development
created_by: dph
creation_date: 2009-09-18T11:45:33Z

[Term]
id: GO:0060916
name: mesenchymal cell proliferation involved in lung development
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph]
is_a: GO:0010463 ! mesenchymal cell proliferation
intersection_of: GO:0010463 ! mesenchymal cell proliferation
intersection_of: part_of GO:0030324 ! lung development
relationship: part_of GO:0030324 ! lung development
created_by: dph
creation_date: 2009-09-18T11:50:17Z

[Term]
id: GO:0060920
name: cardiac pacemaker cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart]
synonym: "pacemaker cell differentiation" BROAD []
is_a: GO:0055007 ! cardiac muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002072 ! nodal myocyte
relationship: results_in_acquisition_of_features_of CL:0002072 ! nodal myocyte
created_by: dph
creation_date: 2009-09-29T11:01:31Z

[Term]
id: GO:0060921
name: sinoatrial node cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart]
synonym: "SA node cell differentiation" EXACT [GOC:mtg_heart]
synonym: "SAN cell differentiation" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "sinus node cell differentiation" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
is_a: GO:0060920 ! cardiac pacemaker cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000409 ! myocyte of sinoatrial node
relationship: part_of GO:0003163 ! sinoatrial node development
relationship: results_in_acquisition_of_features_of CL:1000409 ! myocyte of sinoatrial node
created_by: dph
creation_date: 2009-09-29T11:03:30Z

[Term]
id: GO:0060922
name: atrioventricular node cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node." [GOC:mtg_heart]
synonym: "AV node cell differentiation" RELATED [GOC:mtg_heart]
is_a: GO:0003292 ! cardiac septum cell differentiation
is_a: GO:0060920 ! cardiac pacemaker cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000410 ! myocyte of atrioventricular node
relationship: part_of GO:0003162 ! atrioventricular node development
relationship: results_in_acquisition_of_features_of CL:1000410 ! myocyte of atrioventricular node
created_by: dph
creation_date: 2009-09-29T11:07:06Z

[Term]
id: GO:0060926
name: cardiac pacemaker cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart]
synonym: "pacemaker cell development" BROAD []
is_a: GO:0055013 ! cardiac muscle cell development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of CL:0002072 ! nodal myocyte
relationship: part_of GO:0060920 ! cardiac pacemaker cell differentiation
relationship: results_in_development_of CL:0002072 ! nodal myocyte
created_by: dph
creation_date: 2009-09-29T11:51:55Z

[Term]
id: GO:0060928
name: atrioventricular node cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state." [GOC:mtg_heart]
synonym: "AV node cell development" EXACT [GOC:mtg_heart]
is_a: GO:0060926 ! cardiac pacemaker cell development
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:1000410 ! myocyte of atrioventricular node
relationship: part_of GO:0060922 ! atrioventricular node cell differentiation
relationship: results_in_development_of CL:1000410 ! myocyte of atrioventricular node
created_by: dph
creation_date: 2009-09-29T11:59:26Z

[Term]
id: GO:0060931
name: sinoatrial node cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart]
synonym: "SA node cell development" EXACT [GOC:mtg_heart]
synonym: "SAN cell development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "sinus node cell development" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
is_a: GO:0060926 ! cardiac pacemaker cell development
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:1000409 ! myocyte of sinoatrial node
relationship: part_of GO:0060921 ! sinoatrial node cell differentiation
relationship: results_in_development_of CL:1000409 ! myocyte of sinoatrial node
created_by: dph
creation_date: 2009-09-29T12:05:47Z

[Term]
id: GO:0060932
name: His-Purkinje system cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart]
is_a: GO:0055007 ! cardiac muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0010007 ! His-Purkinje system cell
relationship: part_of GO:0003164 ! His-Purkinje system development
relationship: results_in_acquisition_of_features_of CL:0010007 ! His-Purkinje system cell
created_by: dph
creation_date: 2009-09-29T01:10:32Z

[Term]
id: GO:0060933
name: His-Purkinje system cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart]
is_a: GO:0055006 ! cardiac cell development
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:0010007 ! His-Purkinje system cell
relationship: part_of GO:0060932 ! His-Purkinje system cell differentiation
relationship: results_in_development_of CL:0010007 ! His-Purkinje system cell
created_by: dph
creation_date: 2009-09-29T01:15:02Z

[Term]
id: GO:0060935
name: cardiac fibroblast cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]
is_a: GO:0035051 ! cardiocyte differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002548 ! fibroblast of cardiac tissue
relationship: results_in_acquisition_of_features_of CL:0002548 ! fibroblast of cardiac tissue
created_by: dph
creation_date: 2009-09-29T01:20:04Z

[Term]
id: GO:0060936
name: cardiac fibroblast cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart]
is_a: GO:0055006 ! cardiac cell development
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:0002548 ! fibroblast of cardiac tissue
relationship: part_of GO:0060935 ! cardiac fibroblast cell differentiation
relationship: results_in_development_of CL:0002548 ! fibroblast of cardiac tissue
created_by: dph
creation_date: 2009-09-29T01:23:03Z

[Term]
id: GO:0060945
name: cardiac neuron differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart." [GOC:mtg_heart]
synonym: "heart neuron differentiation" EXACT [GOC:mtg_heart]
is_a: GO:0030182 ! neuron differentiation
is_a: GO:0035051 ! cardiocyte differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0010022 ! cardiac neuron
relationship: part_of GO:0048483 ! autonomic nervous system development
relationship: results_in_acquisition_of_features_of CL:0010022 ! cardiac neuron
created_by: dph
creation_date: 2009-09-29T02:45:33Z

[Term]
id: GO:0060946
name: cardiac blood vessel endothelial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels." [GOC:mtg_heart]
is_a: GO:0003348 ! cardiac endothelial cell differentiation
is_a: GO:0060837 ! blood vessel endothelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0010006 ! cardiac blood vessel endothelial cell
relationship: results_in_acquisition_of_features_of CL:0010006 ! cardiac blood vessel endothelial cell
created_by: dph
creation_date: 2009-09-29T02:48:55Z

[Term]
id: GO:0060950
name: cardiac glial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart." [GOC:mtg_heart]
is_a: GO:0010001 ! glial cell differentiation
is_a: GO:0035051 ! cardiocyte differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0010020 ! cardiac glial cell
relationship: results_in_acquisition_of_features_of CL:0010020 ! cardiac glial cell
created_by: dph
creation_date: 2009-09-29T03:06:37Z

[Term]
id: GO:0060952
name: cardiac glial cell development
namespace: biological_process
def: "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell." [GOC:mtg_heart]
is_a: GO:0021782 ! glial cell development
is_a: GO:0055006 ! cardiac cell development
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:0010020 ! cardiac glial cell
relationship: part_of GO:0060950 ! cardiac glial cell differentiation
relationship: results_in_development_of CL:0010020 ! cardiac glial cell
created_by: dph
creation_date: 2009-09-29T03:09:24Z

[Term]
id: GO:0060956
name: endocardial cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart]
is_a: GO:0003348 ! cardiac endothelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002350 ! endocardial cell
relationship: part_of GO:0003157 ! endocardium development
relationship: results_in_acquisition_of_features_of CL:0002350 ! endocardial cell
created_by: dph
creation_date: 2009-09-29T03:20:39Z

[Term]
id: GO:0060958
name: endocardial cell development
namespace: biological_process
def: "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." [GOC:mtg_heart]
is_a: GO:0001885 ! endothelial cell development
is_a: GO:0055006 ! cardiac cell development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of CL:0002350 ! endocardial cell
relationship: part_of GO:0060956 ! endocardial cell differentiation
relationship: results_in_development_of CL:0002350 ! endocardial cell
created_by: dph
creation_date: 2009-09-29T03:26:59Z

[Term]
id: GO:0060959
name: cardiac neuron development
namespace: biological_process
def: "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state." [GOC:mtg_heart]
synonym: "heart neuron development" EXACT [GOC:mtg_heart]
is_a: GO:0048666 ! neuron development
is_a: GO:0055006 ! cardiac cell development
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:0010022 ! cardiac neuron
relationship: part_of GO:0060945 ! cardiac neuron differentiation
relationship: results_in_development_of CL:0010022 ! cardiac neuron
created_by: dph
creation_date: 2009-09-30T10:14:56Z

[Term]
id: GO:0060973
name: cell migration involved in heart development
namespace: biological_process
def: "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ." [GOC:mtg_heart]
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: part_of GO:0007507 ! heart development
relationship: part_of GO:0007507 ! heart development
created_by: dph
creation_date: 2009-10-06T10:53:49Z

[Term]
id: GO:0060974
name: cell migration involved in heart formation
namespace: biological_process
def: "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells." [GOC:mtg_heart]
is_a: GO:0060973 ! cell migration involved in heart development
intersection_of: GO:0016477 ! cell migration
intersection_of: part_of GO:0060914 ! heart formation
relationship: part_of GO:0060914 ! heart formation
created_by: dph
creation_date: 2009-10-06T10:56:33Z

[Term]
id: GO:0060976
name: coronary vasculature development
namespace: biological_process
def: "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure." [GOC:mtg_heart]
synonym: "cardiac blood vessel development" EXACT [GOC:mtg_heart]
synonym: "cardiac vasculature development" EXACT [GOC:mtg_heart]
synonym: "coronary blood vessel development" EXACT [GOC:mtg_heart]
synonym: "heart blood vessel development" EXACT [GOC:mtg_heart]
synonym: "heart vasculature development" EXACT [GOC:mtg_heart]
is_a: GO:0001568 ! blood vessel development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003498 ! heart blood vessel
relationship: part_of GO:0007507 ! heart development
relationship: results_in_development_of UBERON:0003498 ! heart blood vessel
created_by: dph
creation_date: 2009-10-06T12:15:23Z

[Term]
id: GO:0060977
name: coronary vasculature morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:mtg_heart]
synonym: "cardiac blood vessel morphogenesis" EXACT [GOC:mtg_heart]
synonym: "cardiac vasculature morphogenesis" EXACT [GOC:mtg_heart]
synonym: "coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart]
synonym: "heart blood vessel morphogenesis" EXACT [GOC:mtg_heart]
synonym: "heart vasculature morphogenesis" EXACT [GOC:mtg_heart]
is_a: GO:0048514 ! blood vessel morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003498 ! heart blood vessel
relationship: part_of GO:0060976 ! coronary vasculature development
relationship: results_in_morphogenesis_of UBERON:0003498 ! heart blood vessel
created_by: dph
creation_date: 2009-10-06T12:28:23Z

[Term]
id: GO:0060978
name: angiogenesis involved in coronary vascular morphogenesis
namespace: biological_process
def: "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels." [GOC:mtg_heart]
synonym: "angiogenesis involved in cardiac vascular morphogenesis" EXACT [GOC:mtg_heart]
synonym: "angiogenesis involved in heart vascular morphogenesis" EXACT [GOC:mtg_heart]
synonym: "coronary blood vessel angiogenesis" EXACT [GOC:mtg_heart]
synonym: "coronary vasculature angiogenesis" EXACT [GOC:mtg_heart]
is_a: GO:0001525 ! angiogenesis
intersection_of: GO:0001525 ! angiogenesis
intersection_of: part_of GO:0060976 ! coronary vasculature development
relationship: part_of GO:0060977 ! coronary vasculature morphogenesis
created_by: dph
creation_date: 2009-10-06T02:02:12Z

[Term]
id: GO:0060979
name: vasculogenesis involved in coronary vascular morphogenesis
namespace: biological_process
def: "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes." [GOC:mtg_heart]
synonym: "coronary vasculogenesis" EXACT [GOC:mtg_heart]
synonym: "vasculogenesis involved in coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart]
is_a: GO:0001570 ! vasculogenesis
intersection_of: GO:0001570 ! vasculogenesis
intersection_of: part_of GO:0060977 ! coronary vasculature morphogenesis
relationship: part_of GO:0060977 ! coronary vasculature morphogenesis
created_by: dph
creation_date: 2009-10-06T02:19:42Z

[Term]
id: GO:0060980
name: cell migration involved in coronary vasculogenesis
namespace: biological_process
def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart." [GOC:mtg_heart]
is_a: GO:0035441 ! cell migration involved in vasculogenesis
is_a: GO:0060973 ! cell migration involved in heart development
intersection_of: GO:0016477 ! cell migration
intersection_of: part_of GO:0060979 ! vasculogenesis involved in coronary vascular morphogenesis
relationship: part_of GO:0060979 ! vasculogenesis involved in coronary vascular morphogenesis
created_by: dph
creation_date: 2009-10-06T02:33:06Z

[Term]
id: GO:0060981
name: cell migration involved in coronary angiogenesis
namespace: biological_process
def: "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels." [GOC:mtg_heart]
is_a: GO:0060973 ! cell migration involved in heart development
intersection_of: GO:0016477 ! cell migration
intersection_of: part_of GO:0060978 ! angiogenesis involved in coronary vascular morphogenesis
relationship: part_of GO:0060978 ! angiogenesis involved in coronary vascular morphogenesis
created_by: dph
creation_date: 2009-10-06T02:49:12Z

[Term]
id: GO:0060986
name: endocrine hormone secretion
namespace: biological_process
def: "The regulated release of a hormone into the circulatory system." [GOC:dph]
is_a: GO:0046879 ! hormone secretion
relationship: part_of GO:0050886 ! endocrine process
created_by: dph
creation_date: 2010-01-11T09:03:48Z

[Term]
id: GO:0060993
name: kidney morphogenesis
namespace: biological_process
def: "Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002113 ! kidney
relationship: part_of GO:0001822 ! kidney development
relationship: results_in_morphogenesis_of UBERON:0002113 ! kidney
created_by: dph
creation_date: 2010-01-19T08:16:55Z

[Term]
id: GO:0060995
name: cell-cell signaling involved in kidney development
namespace: biological_process
def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ." [GOC:dph, GOC:mtg_kidney_jan10]
synonym: "cell-cell signalling involved in kidney development" EXACT [GOC:mah]
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: part_of GO:0001822 ! kidney development
relationship: part_of GO:0001822 ! kidney development
created_by: dph
creation_date: 2010-01-19T08:33:40Z

[Term]
id: GO:0061004
name: pattern specification involved in kidney development
namespace: biological_process
def: "Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:mtg_kidney_jan10]
synonym: "kidney pattern formation" RELATED [GOC:mtg_kidney_jan10]
synonym: "kidney pattern specification" EXACT [GOC:mtg_kidney_jan10]
synonym: "pattern formation involved in kidney development" RELATED [GOC:mtg_kidney_jan10]
is_a: GO:0007389 ! pattern specification process
intersection_of: GO:0007389 ! pattern specification process
intersection_of: part_of GO:0001822 ! kidney development
relationship: part_of GO:0001822 ! kidney development
relationship: part_of GO:0072048 ! renal system pattern specification
created_by: dph
creation_date: 2010-01-21T09:05:54Z

[Term]
id: GO:0061005
name: cell differentiation involved in kidney development
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]
is_a: GO:0030154 ! cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: part_of GO:0001822 ! kidney development
relationship: part_of GO:0001822 ! kidney development
created_by: dph
creation_date: 2010-01-21T09:13:55Z

[Term]
id: GO:0061006
name: regulation of cell proliferation involved in kidney morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney." [GOC:dph, GOC:mtg_kidney_jan10]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0042127 ! regulation of cell population proliferation
intersection_of: part_of GO:0060993 ! kidney morphogenesis
relationship: part_of GO:0060993 ! kidney morphogenesis
created_by: dph
creation_date: 2010-01-21T11:25:23Z

[Term]
id: GO:0061007
name: hepaticobiliary system process
namespace: biological_process
def: "An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph]
subset: goslim_generic
synonym: "hepatobiliary system process" EXACT [GOC:dph]
is_a: GO:0003008 ! system process
created_by: dph
creation_date: 2010-01-22T09:09:10Z

[Term]
id: GO:0061008
name: hepaticobiliary system development
namespace: biological_process
def: "The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph]
synonym: "hepatobiliary system development" EXACT [GOC:dph]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002423 ! hepatobiliary system
relationship: results_in_development_of UBERON:0002423 ! hepatobiliary system
created_by: dph
creation_date: 2010-01-22T09:11:59Z

[Term]
id: GO:0061009
name: common bile duct development
namespace: biological_process
def: "The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine." [PMID:20614624]
synonym: "bile duct development" EXACT [GOC:dph]
synonym: "CBD development" EXACT [PMID:20614624]
synonym: "EHBD development" BROAD [PMID:20614624]
synonym: "extrahepatic bile duct development" BROAD [PMID:20614624]
is_a: GO:0035295 ! tube development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002394 ! bile duct
relationship: part_of GO:0061008 ! hepaticobiliary system development
relationship: results_in_development_of UBERON:0002394 ! bile duct
created_by: dph
creation_date: 2010-01-22T09:17:13Z

[Term]
id: GO:0061010
name: gallbladder development
namespace: biological_process
def: "The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile." [GOC:dph]
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002110 ! gallbladder
relationship: part_of GO:0061008 ! hepaticobiliary system development
relationship: results_in_development_of UBERON:0002110 ! gallbladder
created_by: dph
creation_date: 2010-01-22T09:38:44Z

[Term]
id: GO:0061011
name: hepatic duct development
namespace: biological_process
def: "The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct." [GOC:dph, PMID:20614624]
is_a: GO:0061009 ! common bile duct development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001175 ! common hepatic duct
relationship: results_in_development_of UBERON:0001175 ! common hepatic duct
created_by: dph
creation_date: 2010-01-22T09:44:39Z

[Term]
id: GO:0061017
name: hepatoblast differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes." [GOC:dph, PMID:15226394]
is_a: GO:0030855 ! epithelial cell differentiation
is_a: GO:0048863 ! stem cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000488 ! cholangiocyte
relationship: part_of GO:0001889 ! liver development
relationship: results_in_acquisition_of_features_of CL:1000488 ! cholangiocyte
created_by: dph
creation_date: 2010-02-02T09:08:03Z

[Term]
id: GO:0061024
name: membrane organization
namespace: biological_process
alt_id: GO:0016044
alt_id: GO:0044802
def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:dph, GOC:tb]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_pir
subset: goslim_pombe
subset: goslim_prokaryote
synonym: "cellular membrane organisation" EXACT []
synonym: "cellular membrane organization" EXACT []
synonym: "membrane organisation" EXACT [GOC:mah]
synonym: "membrane organization and biogenesis" RELATED [GOC:mah]
synonym: "single-organism membrane organization" RELATED []
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0016020 ! membrane
relationship: results_in_organization_of GO:0016020 ! membrane
created_by: jl
creation_date: 2010-02-08T02:43:11Z

[Term]
id: GO:0061025
name: membrane fusion
namespace: biological_process
alt_id: GO:0006944
alt_id: GO:0044801
def: "The membrane organization process that joins two lipid bilayers to form a single membrane." [GOC:dph, GOC:tb]
subset: goslim_yeast
synonym: "cellular membrane fusion" EXACT []
synonym: "single-organism membrane fusion" RELATED []
xref: Wikipedia:Lipid_bilayer_fusion
is_a: GO:0061024 ! membrane organization
intersection_of: GO:0061024 ! membrane organization
intersection_of: results_in_fusion_of GO:0016020 ! membrane
relationship: results_in_fusion_of GO:0016020 ! membrane
created_by: jl
creation_date: 2010-02-08T02:48:06Z

[Term]
id: GO:0061027
name: umbilical cord development
namespace: biological_process
def: "The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002331 ! umbilical cord
relationship: results_in_development_of UBERON:0002331 ! umbilical cord
created_by: dph
creation_date: 2010-02-09T09:09:22Z

[Term]
id: GO:0061032
name: visceral serous pericardium development
namespace: biological_process
def: "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium." [GOC:dph, GOC:yaf]
synonym: "epicardium development" EXACT [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002425 ! visceral serous pericardium
relationship: part_of GO:0060039 ! pericardium development
relationship: results_in_development_of UBERON:0002425 ! visceral serous pericardium
created_by: dph
creation_date: 2010-02-09T09:52:49Z

[Term]
id: GO:0061035
name: regulation of cartilage development
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph]
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051216 ! cartilage development
relationship: regulates GO:0051216 ! cartilage development
created_by: dph
creation_date: 2010-02-09T03:41:35Z

[Term]
id: GO:0061036
name: positive regulation of cartilage development
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:0061035 ! regulation of cartilage development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051216 ! cartilage development
relationship: positively_regulates GO:0051216 ! cartilage development
created_by: dph
creation_date: 2010-02-09T03:41:35Z

[Term]
id: GO:0061037
name: negative regulation of cartilage development
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0061035 ! regulation of cartilage development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051216 ! cartilage development
relationship: negatively_regulates GO:0051216 ! cartilage development
created_by: dph
creation_date: 2010-02-09T03:41:35Z

[Term]
id: GO:0061038
name: uterus morphogenesis
namespace: biological_process
def: "The process in which anatomical structures of the uterus are generated and organized." [GOC:BHF, GOC:dph]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000995 ! uterus
relationship: part_of GO:0060065 ! uterus development
relationship: results_in_morphogenesis_of UBERON:0000995 ! uterus
created_by: dph
creation_date: 2010-02-22T11:12:35Z

[Term]
id: GO:0061040
name: female gonad morphogenesis
namespace: biological_process
def: "The process in which a female gonad is generated and organized." [GOC:BHF, GOC:dph]
synonym: "ovary morphogenesis" RELATED [GOC:dph, GOC:tb]
is_a: GO:0035262 ! gonad morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000992 ! ovary
relationship: part_of GO:0008585 ! female gonad development
relationship: results_in_morphogenesis_of UBERON:0000992 ! ovary
created_by: dph
creation_date: 2010-02-22T11:29:28Z

[Term]
id: GO:0061046
name: regulation of branching involved in lung morphogenesis
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf]
is_a: GO:0060688 ! regulation of morphogenesis of a branching structure
is_a: GO:1905330 ! regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis
relationship: regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis
created_by: dph
creation_date: 2010-02-25T10:41:38Z

[Term]
id: GO:0061047
name: positive regulation of branching involved in lung morphogenesis
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf]
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis
is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis
relationship: positively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis
created_by: dph
creation_date: 2010-02-25T10:50:01Z

[Term]
id: GO:0061048
name: negative regulation of branching involved in lung morphogenesis
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf]
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis
is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis
relationship: negatively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis
created_by: dph
creation_date: 2010-02-25T10:51:31Z

[Term]
id: GO:0061049
name: cell growth involved in cardiac muscle cell development
namespace: biological_process
def: "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph]
synonym: "cardiac muscle cell hypertrophy" RELATED [GOC:dph]
synonym: "cardiomyocyte growth" RELATED [GOC:dph]
synonym: "heart muscle cell growth" RELATED [GOC:dph]
is_a: GO:0048588 ! developmental cell growth
intersection_of: GO:0016049 ! cell growth
intersection_of: part_of GO:0055013 ! cardiac muscle cell development
relationship: part_of GO:0003301 ! physiological cardiac muscle hypertrophy
relationship: part_of GO:0055013 ! cardiac muscle cell development
created_by: dph
creation_date: 2010-02-25T12:56:07Z

[Term]
id: GO:0061050
name: regulation of cell growth involved in cardiac muscle cell development
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph]
is_a: GO:0001558 ! regulation of cell growth
is_a: GO:0055021 ! regulation of cardiac muscle tissue growth
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061049 ! cell growth involved in cardiac muscle cell development
relationship: regulates GO:0061049 ! cell growth involved in cardiac muscle cell development
created_by: dph
creation_date: 2010-02-25T01:05:16Z

[Term]
id: GO:0061051
name: positive regulation of cell growth involved in cardiac muscle cell development
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph]
is_a: GO:0010613 ! positive regulation of cardiac muscle hypertrophy
is_a: GO:0030307 ! positive regulation of cell growth
is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation
is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth
is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development
relationship: positively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development
created_by: dph
creation_date: 2010-02-25T01:08:08Z

[Term]
id: GO:0061052
name: negative regulation of cell growth involved in cardiac muscle cell development
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph]
is_a: GO:0010614 ! negative regulation of cardiac muscle hypertrophy
is_a: GO:0030308 ! negative regulation of cell growth
is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation
is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth
is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development
relationship: negatively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development
created_by: dph
creation_date: 2010-02-25T01:11:30Z

[Term]
id: GO:0061053
name: somite development
namespace: biological_process
def: "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [GOC:dph]
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002329 ! somite
relationship: part_of GO:0009790 ! embryo development
relationship: results_in_development_of UBERON:0002329 ! somite
created_by: dph
creation_date: 2010-03-02T12:05:13Z

[Term]
id: GO:0061054
name: dermatome development
namespace: biological_process
def: "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004016 ! dermatome
relationship: part_of GO:0061053 ! somite development
relationship: results_in_development_of UBERON:0004016 ! dermatome
created_by: dph
creation_date: 2010-03-02T12:07:37Z

[Term]
id: GO:0061055
name: myotome development
namespace: biological_process
def: "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle." [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003082 ! myotome
relationship: part_of GO:0061053 ! somite development
relationship: results_in_development_of UBERON:0003082 ! myotome
created_by: dph
creation_date: 2010-03-02T12:11:01Z

[Term]
id: GO:0061056
name: sclerotome development
namespace: biological_process
def: "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph]
is_a: GO:0060485 ! mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003089 ! sclerotome
relationship: part_of GO:0061053 ! somite development
relationship: results_in_development_of UBERON:0003089 ! sclerotome
created_by: dph
creation_date: 2010-03-02T12:12:40Z

[Term]
id: GO:0061061
name: muscle structure development
namespace: biological_process
def: "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." [GOC:dph]
subset: goslim_drosophila
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005090 ! muscle structure
relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: results_in_development_of UBERON:0005090 ! muscle structure
created_by: dph
creation_date: 2010-03-09T08:55:14Z

[Term]
id: GO:0061062
name: regulation of nematode larval development
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv]
is_a: GO:0048580 ! regulation of post-embryonic development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002119 ! nematode larval development
relationship: regulates GO:0002119 ! nematode larval development
created_by: dph
creation_date: 2010-03-11T12:59:21Z

[Term]
id: GO:0061063
name: positive regulation of nematode larval development
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv]
is_a: GO:0048582 ! positive regulation of post-embryonic development
is_a: GO:0061062 ! regulation of nematode larval development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002119 ! nematode larval development
relationship: positively_regulates GO:0002119 ! nematode larval development
created_by: dph
creation_date: 2010-03-11T01:03:34Z

[Term]
id: GO:0061064
name: negative regulation of nematode larval development
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv]
is_a: GO:0048581 ! negative regulation of post-embryonic development
is_a: GO:0061062 ! regulation of nematode larval development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002119 ! nematode larval development
relationship: negatively_regulates GO:0002119 ! nematode larval development
created_by: dph
creation_date: 2010-03-11T01:04:39Z

[Term]
id: GO:0061068
name: urethra development
namespace: biological_process
def: "The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body." [GOC:dph]
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000057 ! urethra
relationship: part_of GO:0072001 ! renal system development
relationship: results_in_development_of UBERON:0000057 ! urethra
created_by: dph
creation_date: 2010-03-12T08:24:52Z

[Term]
id: GO:0061069
name: male urethra development
namespace: biological_process
def: "The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body." [GOC:dph]
is_a: GO:0061068 ! urethra development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001333 ! male urethra
relationship: results_in_development_of UBERON:0001333 ! male urethra
created_by: dph
creation_date: 2010-03-12T08:28:19Z

[Term]
id: GO:0061070
name: female urethra development
namespace: biological_process
def: "The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening." [GOC:dph]
is_a: GO:0061068 ! urethra development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001334 ! female urethra
relationship: results_in_development_of UBERON:0001334 ! female urethra
created_by: dph
creation_date: 2010-03-12T08:29:43Z

[Term]
id: GO:0061071
name: urethra epithelium development
namespace: biological_process
def: "The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes." [GOC:dph]
is_a: GO:0035295 ! tube development
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002325 ! epithelium of urethra
relationship: part_of GO:0061068 ! urethra development
relationship: results_in_development_of UBERON:0002325 ! epithelium of urethra
created_by: dph
creation_date: 2010-03-12T08:36:53Z

[Term]
id: GO:0061072
name: iris morphogenesis
namespace: biological_process
def: "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina." [GOC:dph]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001769 ! iris
relationship: part_of GO:0048593 ! camera-type eye morphogenesis
relationship: results_in_morphogenesis_of UBERON:0001769 ! iris
created_by: dph
creation_date: 2010-03-16T10:48:42Z

[Term]
id: GO:0061073
name: ciliary body morphogenesis
namespace: biological_process
def: "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." [GOC:dph]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001775 ! ciliary body
relationship: part_of GO:0048593 ! camera-type eye morphogenesis
relationship: results_in_morphogenesis_of UBERON:0001775 ! ciliary body
created_by: dph
creation_date: 2010-03-16T10:55:19Z

[Term]
id: GO:0061074
name: regulation of neural retina development
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003407 ! neural retina development
relationship: regulates GO:0003407 ! neural retina development
created_by: dph
creation_date: 2010-03-16T11:47:05Z

[Term]
id: GO:0061075
name: positive regulation of neural retina development
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph]
is_a: GO:0061074 ! regulation of neural retina development
is_a: GO:1902868 ! positive regulation of retina development in camera-type eye
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003407 ! neural retina development
relationship: positively_regulates GO:0003407 ! neural retina development
created_by: dph
creation_date: 2010-03-16T11:59:48Z

[Term]
id: GO:0061076
name: negative regulation of neural retina development
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph]
is_a: GO:0061074 ! regulation of neural retina development
is_a: GO:1902867 ! negative regulation of retina development in camera-type eye
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003407 ! neural retina development
relationship: negatively_regulates GO:0003407 ! neural retina development
created_by: dph
creation_date: 2010-03-16T12:46:11Z

[Term]
id: GO:0061080
name: right horn of sinus venosus development
namespace: biological_process
def: "The progression of the right horn of the sinus venosus from its formation to the mature structure." [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005092 ! right horn of sinus venosus
relationship: part_of GO:0003235 ! sinus venosus development
relationship: results_in_development_of UBERON:0005092 ! right horn of sinus venosus
created_by: dph
creation_date: 2010-04-08T02:45:10Z

[Term]
id: GO:0061100
name: lung neuroendocrine cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium." [GOC:dph, PMID:9126746]
is_a: GO:0061101 ! neuroendocrine cell differentiation
is_a: GO:0061140 ! lung secretory cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000223 ! lung neuroendocrine cell
relationship: results_in_acquisition_of_features_of CL:1000223 ! lung neuroendocrine cell
created_by: dph
creation_date: 2010-04-27T03:28:46Z

[Term]
id: GO:0061101
name: neuroendocrine cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance." [GOC:dph]
is_a: GO:0030182 ! neuron differentiation
is_a: GO:0060563 ! neuroepithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000165 ! neuroendocrine cell
relationship: results_in_acquisition_of_features_of CL:0000165 ! neuroendocrine cell
created_by: dph
creation_date: 2010-04-28T09:42:20Z

[Term]
id: GO:0061102
name: stomach neuroendocrine cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium." [GOC:dph, PMID:18173746]
synonym: "gastric neuroendocrine cell differentiation" RELATED [GOC:dph]
is_a: GO:0035883 ! enteroendocrine cell differentiation
is_a: GO:0061101 ! neuroendocrine cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000222 ! stomach neuroendocrine cell
relationship: part_of GO:0062094 ! stomach development
relationship: results_in_acquisition_of_features_of CL:1000222 ! stomach neuroendocrine cell
created_by: dph
creation_date: 2010-04-28T09:47:07Z

[Term]
id: GO:0061105
name: regulation of stomach neuroendocrine cell differentiation
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph]
is_a: GO:0030856 ! regulation of epithelial cell differentiation
is_a: GO:0045664 ! regulation of neuron differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061102 ! stomach neuroendocrine cell differentiation
relationship: regulates GO:0061102 ! stomach neuroendocrine cell differentiation
created_by: dph
creation_date: 2010-04-29T12:19:37Z

[Term]
id: GO:0061106
name: negative regulation of stomach neuroendocrine cell differentiation
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph]
is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation
is_a: GO:0045665 ! negative regulation of neuron differentiation
is_a: GO:0061105 ! regulation of stomach neuroendocrine cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061102 ! stomach neuroendocrine cell differentiation
relationship: negatively_regulates GO:0061102 ! stomach neuroendocrine cell differentiation
created_by: dph
creation_date: 2010-04-29T12:23:05Z

[Term]
id: GO:0061107
name: seminal vesicle development
namespace: biological_process
def: "The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen." [GOC:dph]
is_a: GO:0048608 ! reproductive structure development
is_a: GO:0048732 ! gland development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000998 ! seminal vesicle
relationship: results_in_development_of UBERON:0000998 ! seminal vesicle
created_by: dph
creation_date: 2010-04-30T10:17:30Z

[Term]
id: GO:0061108
name: seminal vesicle epithelium development
namespace: biological_process
def: "The progression of the seminal vesicle epithelium over time, from its formation to the mature structure." [GOC:dph]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0035295 ! tube development
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004805 ! seminal vesicle epithelium
relationship: part_of GO:0061107 ! seminal vesicle development
relationship: results_in_development_of UBERON:0004805 ! seminal vesicle epithelium
created_by: dph
creation_date: 2010-04-30T10:19:54Z

[Term]
id: GO:0061109
name: dense core granule organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells." [GOC:dph]
synonym: "dense core granule organisation" EXACT [GOC:mah]
is_a: GO:0033363 ! secretory granule organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0031045 ! dense core granule
relationship: results_in_organization_of GO:0031045 ! dense core granule
created_by: dph
creation_date: 2010-05-01T09:34:37Z

[Term]
id: GO:0061111
name: epithelial-mesenchymal cell signaling involved in lung development
namespace: biological_process
def: "Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ." [GOC:dph]
synonym: "epithelial-mesenchymal cell signalling involved in lung development" EXACT [GOC:mah]
is_a: GO:0060495 ! cell-cell signaling involved in lung development
is_a: GO:0060684 ! epithelial-mesenchymal cell signaling
intersection_of: GO:0060684 ! epithelial-mesenchymal cell signaling
intersection_of: part_of GO:0030324 ! lung development
created_by: dph
creation_date: 2010-05-05T11:14:38Z

[Term]
id: GO:0061113
name: pancreas morphogenesis
namespace: biological_process
def: "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized." [GOC:dph]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001264 ! pancreas
relationship: part_of GO:0031016 ! pancreas development
relationship: results_in_morphogenesis_of UBERON:0001264 ! pancreas
created_by: dph
creation_date: 2010-05-05T11:55:30Z

[Term]
id: GO:0061114
name: branching involved in pancreas morphogenesis
namespace: biological_process
def: "The process in which the branches of the pancreas are generated and organized." [GOC:dph]
is_a: GO:0061138 ! morphogenesis of a branching epithelium
intersection_of: GO:0061138 ! morphogenesis of a branching epithelium
intersection_of: part_of GO:0061113 ! pancreas morphogenesis
relationship: part_of GO:0061113 ! pancreas morphogenesis
created_by: dph
creation_date: 2010-05-05T12:03:04Z

[Term]
id: GO:0061117
name: negative regulation of heart growth
namespace: biological_process
def: "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:hjd]
is_a: GO:0046621 ! negative regulation of organ growth
is_a: GO:0060420 ! regulation of heart growth
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060419 ! heart growth
relationship: negatively_regulates GO:0060419 ! heart growth
created_by: dph
creation_date: 2010-05-17T07:31:28Z

[Term]
id: GO:0061130
name: pancreatic bud formation
namespace: biological_process
def: "The morphogenetic process in which the foregut region specified to become the pancreas forms a bud." [GOC:dph]
is_a: GO:0048645 ! animal organ formation
is_a: GO:0061114 ! branching involved in pancreas morphogenesis
is_a: GO:0072175 ! epithelial tube formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003922 ! pancreatic epithelial bud
relationship: results_in_formation_of_anatomical_entity UBERON:0003922 ! pancreatic epithelial bud
created_by: dph
creation_date: 2010-05-17T09:33:40Z

[Term]
id: GO:0061138
name: morphogenesis of a branching epithelium
namespace: biological_process
def: "The process in which the anatomical structures of a branched epithelium are generated and organized." [GOC:dph]
is_a: GO:0001763 ! morphogenesis of a branching structure
is_a: GO:0002009 ! morphogenesis of an epithelium
created_by: dph
creation_date: 2010-05-25T09:05:34Z

[Term]
id: GO:0061140
name: lung secretory cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part." [GOC:dph]
is_a: GO:0060487 ! lung epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000272 ! lung secretory cell
relationship: results_in_acquisition_of_features_of CL:1000272 ! lung secretory cell
created_by: dph
creation_date: 2010-05-25T09:28:53Z

[Term]
id: GO:0061141
name: lung ciliated cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells." [GOC:cilia, GOC:dph, GOC:krc]
is_a: GO:0060487 ! lung epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000271 ! lung ciliated cell
relationship: results_in_acquisition_of_features_of CL:1000271 ! lung ciliated cell
created_by: dph
creation_date: 2010-05-25T09:31:14Z

[Term]
id: GO:0061147
name: endocardial endothelium development
namespace: biological_process
def: "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph]
is_a: GO:0003158 ! endothelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005316 ! endocardial endothelium
relationship: part_of GO:0003157 ! endocardium development
relationship: results_in_development_of UBERON:0005316 ! endocardial endothelium
created_by: dph
creation_date: 2010-06-03T09:15:31Z

[Term]
id: GO:0061148
name: extracellular matrix organization involved in endocardium development
namespace: biological_process
def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph]
synonym: "extracellular matrix organisation involved in endocardium development" EXACT [GOC:mah]
is_a: GO:0030198 ! extracellular matrix organization
intersection_of: GO:0030198 ! extracellular matrix organization
intersection_of: part_of GO:0003157 ! endocardium development
relationship: part_of GO:0003157 ! endocardium development
created_by: dph
creation_date: 2010-06-03T09:18:02Z

[Term]
id: GO:0061154
name: endothelial tube morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:dph, GOC:yaf]
is_a: GO:0003159 ! morphogenesis of an endothelium
is_a: GO:0060562 ! epithelial tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003915 ! endothelial tube
relationship: results_in_morphogenesis_of UBERON:0003915 ! endothelial tube
created_by: dph
creation_date: 2010-06-15T09:05:00Z

[Term]
id: GO:0061155
name: pulmonary artery endothelial tube morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery." [GOC:dph, GOC:yaf]
is_a: GO:0061154 ! endothelial tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005317 ! pulmonary artery endothelium
relationship: part_of GO:0061156 ! pulmonary artery morphogenesis
relationship: results_in_morphogenesis_of UBERON:0005317 ! pulmonary artery endothelium
created_by: dph
creation_date: 2010-06-15T09:09:04Z

[Term]
id: GO:0061156
name: pulmonary artery morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs." [GOC:dph, GOC:yaf]
is_a: GO:0048844 ! artery morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002012 ! pulmonary artery
relationship: results_in_morphogenesis_of UBERON:0002012 ! pulmonary artery
created_by: dph
creation_date: 2010-06-15T09:13:47Z

[Term]
id: GO:0061181
name: regulation of chondrocyte development
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph]
is_a: GO:0032330 ! regulation of chondrocyte differentiation
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002063 ! chondrocyte development
relationship: regulates GO:0002063 ! chondrocyte development
created_by: dph
creation_date: 2010-07-14T08:28:52Z

[Term]
id: GO:0061182
name: negative regulation of chondrocyte development
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph]
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0032331 ! negative regulation of chondrocyte differentiation
is_a: GO:0061181 ! regulation of chondrocyte development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002063 ! chondrocyte development
relationship: negatively_regulates GO:0002063 ! chondrocyte development
created_by: dph
creation_date: 2010-07-14T08:33:05Z

[Term]
id: GO:0061183
name: regulation of dermatome development
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061054 ! dermatome development
relationship: regulates GO:0061054 ! dermatome development
created_by: dph
creation_date: 2010-07-14T08:40:26Z

[Term]
id: GO:0061184
name: positive regulation of dermatome development
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph]
is_a: GO:0040019 ! positive regulation of embryonic development
is_a: GO:0061183 ! regulation of dermatome development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061054 ! dermatome development
relationship: positively_regulates GO:0061054 ! dermatome development
created_by: dph
creation_date: 2010-07-14T08:42:03Z

[Term]
id: GO:0061185
name: negative regulation of dermatome development
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph]
is_a: GO:0045992 ! negative regulation of embryonic development
is_a: GO:0061183 ! regulation of dermatome development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061054 ! dermatome development
relationship: negatively_regulates GO:0061054 ! dermatome development
created_by: dph
creation_date: 2010-07-14T08:43:08Z

[Term]
id: GO:0061189
name: positive regulation of sclerotome development
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:BHF, GOC:dph]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0061190 ! regulation of sclerotome development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061056 ! sclerotome development
relationship: positively_regulates GO:0061056 ! sclerotome development
created_by: dph
creation_date: 2010-07-14T09:17:23Z

[Term]
id: GO:0061190
name: regulation of sclerotome development
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061056 ! sclerotome development
relationship: regulates GO:0061056 ! sclerotome development
created_by: dph
creation_date: 2010-07-14T09:19:47Z

[Term]
id: GO:0061205
name: paramesonephric duct development
namespace: biological_process
def: "The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin." [GOC:dph, GOC:yaf]
synonym: "Mullerian duct development" EXACT [GOC:dph]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0035295 ! tube development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003890 ! Mullerian duct
relationship: results_in_development_of UBERON:0003890 ! Mullerian duct
created_by: dph
creation_date: 2010-07-30T10:54:47Z

[Term]
id: GO:0061206
name: mesonephros morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the mesonephros are generated and organized." [GOC:mtg_kidney_jan10]
synonym: "Wolffian body morphogenesis" EXACT [GOC:dph]
is_a: GO:0060993 ! kidney morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000080 ! mesonephros
relationship: part_of GO:0001823 ! mesonephros development
relationship: results_in_morphogenesis_of UBERON:0000080 ! mesonephros
created_by: dph
creation_date: 2010-08-17T03:11:10Z

[Term]
id: GO:0061208
name: cell differentiation involved in mesonephros development
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]
is_a: GO:0061005 ! cell differentiation involved in kidney development
intersection_of: GO:0030154 ! cell differentiation
intersection_of: part_of GO:0001823 ! mesonephros development
relationship: part_of GO:0001823 ! mesonephros development
created_by: dph
creation_date: 2010-08-17T03:21:23Z

[Term]
id: GO:0061209
name: cell proliferation involved in mesonephros development
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072111 ! cell proliferation involved in kidney development
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: part_of GO:0001823 ! mesonephros development
relationship: part_of GO:0001823 ! mesonephros development
created_by: dph
creation_date: 2010-08-17T03:22:46Z

[Term]
id: GO:0061210
name: cell-cell signaling involved in mesonephros development
namespace: biological_process
def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10]
synonym: "cell-cell signalling involved in mesonephros development" EXACT [GOC:mah]
is_a: GO:0060995 ! cell-cell signaling involved in kidney development
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: part_of GO:0001823 ! mesonephros development
relationship: part_of GO:0001823 ! mesonephros development
created_by: dph
creation_date: 2010-08-17T03:24:08Z

[Term]
id: GO:0061211
name: mesonephric collecting duct development
namespace: biological_process
def: "The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10]
is_a: GO:0072044 ! collecting duct development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005319 ! mesonephric collecting duct
relationship: part_of GO:0001823 ! mesonephros development
relationship: results_in_development_of UBERON:0005319 ! mesonephric collecting duct
created_by: dph
creation_date: 2010-08-17T03:25:51Z

[Term]
id: GO:0061213
name: positive regulation of mesonephros development
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10]
is_a: GO:0061217 ! regulation of mesonephros development
is_a: GO:0090184 ! positive regulation of kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001823 ! mesonephros development
relationship: positively_regulates GO:0001823 ! mesonephros development
created_by: dph
creation_date: 2010-08-17T03:39:35Z

[Term]
id: GO:0061214
name: mesonephric smooth muscle tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10]
is_a: GO:0072194 ! kidney smooth muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005321 ! mesonephric smooth muscle tissue
relationship: part_of GO:0001823 ! mesonephros development
relationship: results_in_development_of UBERON:0005321 ! mesonephric smooth muscle tissue
created_by: dph
creation_date: 2010-08-17T03:29:54Z

[Term]
id: GO:0061215
name: mesonephric nephron development
namespace: biological_process
def: "The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0072006 ! nephron development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005322 ! mesonephric nephron
relationship: part_of GO:0001823 ! mesonephros development
relationship: results_in_development_of UBERON:0005322 ! mesonephric nephron
created_by: dph
creation_date: 2010-08-17T03:31:08Z

[Term]
id: GO:0061217
name: regulation of mesonephros development
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10]
is_a: GO:0090183 ! regulation of kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001823 ! mesonephros development
relationship: regulates GO:0001823 ! mesonephros development
created_by: dph
creation_date: 2010-08-17T03:35:31Z

[Term]
id: GO:0061218
name: negative regulation of mesonephros development
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10]
is_a: GO:0061217 ! regulation of mesonephros development
is_a: GO:0090185 ! negative regulation of kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001823 ! mesonephros development
relationship: negatively_regulates GO:0001823 ! mesonephros development
created_by: dph
creation_date: 2010-08-17T03:43:06Z

[Term]
id: GO:0061219
name: mesonephric mesenchyme development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072074 ! kidney mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005323 ! mesonephric mesenchyme
relationship: part_of GO:0001823 ! mesonephros development
relationship: results_in_development_of UBERON:0005323 ! mesonephric mesenchyme
created_by: dph
creation_date: 2010-08-17T03:45:44Z

[Term]
id: GO:0061221
name: mesonephric mesenchyme morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072131 ! kidney mesenchyme morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005323 ! mesonephric mesenchyme
relationship: part_of GO:0061219 ! mesonephric mesenchyme development
relationship: results_in_morphogenesis_of UBERON:0005323 ! mesonephric mesenchyme
created_by: dph
creation_date: 2010-08-19T01:17:38Z

[Term]
id: GO:0061227
name: pattern specification involved in mesonephros development
namespace: biological_process
def: "Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10]
synonym: "mesonephros pattern formation" RELATED [GOC:mtg_kidney_jan10]
synonym: "mesonephros pattern specification" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0061004 ! pattern specification involved in kidney development
intersection_of: GO:0007389 ! pattern specification process
intersection_of: part_of GO:0001823 ! mesonephros development
relationship: part_of GO:0001823 ! mesonephros development
created_by: dph
creation_date: 2010-08-19T02:22:22Z

[Term]
id: GO:0061228
name: mesonephric nephron morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072028 ! nephron morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005322 ! mesonephric nephron
relationship: part_of GO:0061206 ! mesonephros morphogenesis
relationship: part_of GO:0061215 ! mesonephric nephron development
relationship: results_in_morphogenesis_of UBERON:0005322 ! mesonephric nephron
created_by: dph
creation_date: 2010-08-19T02:26:24Z

[Term]
id: GO:0061235
name: mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis
namespace: biological_process
def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10]
is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis
relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis
created_by: dph
creation_date: 2010-08-19T02:57:11Z

[Term]
id: GO:0061241
name: mesonephric nephron epithelium development
namespace: biological_process
def: "The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072009 ! nephron epithelium development
is_a: GO:0072163 ! mesonephric epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005330 ! mesonephric nephron epithelium
relationship: part_of GO:0061215 ! mesonephric nephron development
relationship: results_in_development_of UBERON:0005330 ! mesonephric nephron epithelium
created_by: dph
creation_date: 2010-08-19T03:11:59Z

[Term]
id: GO:0061243
name: mesonephric renal vesicle morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10]
is_a: GO:0072077 ! renal vesicle morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005331 ! mesonephric renal vesicle
relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis
relationship: results_in_morphogenesis_of UBERON:0005331 ! mesonephric renal vesicle
created_by: dph
creation_date: 2010-08-19T03:20:21Z

[Term]
id: GO:0061261
name: mesenchymal to epithelial transition involved in mesonephros morphogenesis
namespace: biological_process
def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros." [GOC:mtg_kidney_jan10]
synonym: "mesonephric mesenchyme to epithelial transition" RELATED [GOC:mtg_kidney_jan10]
is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development
is_a: GO:0060231 ! mesenchymal to epithelial transition
is_a: GO:0061208 ! cell differentiation involved in mesonephros development
intersection_of: GO:0060231 ! mesenchymal to epithelial transition
intersection_of: part_of GO:0061206 ! mesonephros morphogenesis
relationship: part_of GO:0061206 ! mesonephros morphogenesis
created_by: dph
creation_date: 2010-08-30T02:35:15Z

[Term]
id: GO:0061262
name: mesonephric renal vesicle formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the mesonephros." [GOC:mtg_kidney_jan10]
synonym: "mesonephros formation" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0072033 ! renal vesicle formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005331 ! mesonephric renal vesicle
relationship: part_of GO:0061243 ! mesonephric renal vesicle morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0005331 ! mesonephric renal vesicle
created_by: dph
creation_date: 2010-08-30T02:41:20Z

[Term]
id: GO:0061271
name: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation
namespace: biological_process
def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10]
is_a: GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation
intersection_of: GO:0060231 ! mesenchymal to epithelial transition
intersection_of: part_of GO:0061262 ! mesonephric renal vesicle formation
relationship: part_of GO:0061262 ! mesonephric renal vesicle formation
created_by: dph
creation_date: 2010-08-30T03:26:30Z

[Term]
id: GO:0061285
name: mesonephric capsule development
namespace: biological_process
def: "The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [GOC:mtg_kidney_jan10]
is_a: GO:0072127 ! renal capsule development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0006170 ! mesonephric capsule
relationship: part_of GO:0001823 ! mesonephros development
relationship: results_in_development_of UBERON:0006170 ! mesonephric capsule
created_by: dph
creation_date: 2010-09-02T01:50:06Z

[Term]
id: GO:0061286
name: mesonephric capsule morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10]
is_a: GO:0072128 ! renal capsule morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0006170 ! mesonephric capsule
relationship: part_of GO:0061285 ! mesonephric capsule development
relationship: results_in_morphogenesis_of UBERON:0006170 ! mesonephric capsule
created_by: dph
creation_date: 2010-09-02T01:53:31Z

[Term]
id: GO:0061287
name: mesonephric capsule formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10]
is_a: GO:0072129 ! renal capsule formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0006170 ! mesonephric capsule
relationship: part_of GO:0061286 ! mesonephric capsule morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0006170 ! mesonephric capsule
created_by: dph
creation_date: 2010-09-02T01:55:03Z

[Term]
id: GO:0061295
name: regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
namespace: biological_process
def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW []
synonym: "regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT []
is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
relationship: regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis
relationship: regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
created_by: dph
creation_date: 2010-09-06T09:48:56Z

[Term]
id: GO:0061296
name: negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
namespace: biological_process
def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW []
synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT []
is_a: GO:0061218 ! negative regulation of mesonephros development
is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
relationship: negatively_regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis
relationship: negatively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
created_by: dph
creation_date: 2010-09-06T09:54:49Z

[Term]
id: GO:0061297
name: positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
namespace: biological_process
def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW []
synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT []
is_a: GO:0061213 ! positive regulation of mesonephros development
is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
relationship: positively_regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis
relationship: positively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
created_by: dph
creation_date: 2010-09-06T09:58:59Z

[Term]
id: GO:0061298
name: retina vasculature development in camera-type eye
namespace: biological_process
def: "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph]
synonym: "retinal vasculature development" EXACT [GOC:dph]
is_a: GO:0001944 ! vasculature development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004864 ! vasculature of retina
relationship: part_of GO:0060041 ! retina development in camera-type eye
relationship: results_in_development_of UBERON:0004864 ! vasculature of retina
created_by: dph
creation_date: 2010-09-06T03:27:06Z

[Term]
id: GO:0061299
name: retina vasculature morphogenesis in camera-type eye
namespace: biological_process
def: "The process in which the vasculature of the retina is generated and organized." [GOC:BHF, GOC:dph]
synonym: "retinal vasculature morphogenesis" EXACT [GOC:dph]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004864 ! vasculature of retina
relationship: part_of GO:0061298 ! retina vasculature development in camera-type eye
relationship: results_in_morphogenesis_of UBERON:0004864 ! vasculature of retina
created_by: dph
creation_date: 2010-09-06T03:28:25Z

[Term]
id: GO:0061303
name: cornea development in camera-type eye
namespace: biological_process
def: "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye." [GOC:dph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000964 ! cornea
relationship: part_of GO:0043010 ! camera-type eye development
relationship: results_in_development_of UBERON:0000964 ! cornea
created_by: dph
creation_date: 2010-09-14T02:09:08Z

[Term]
id: GO:0061304
name: retinal blood vessel morphogenesis
namespace: biological_process
def: "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph]
is_a: GO:0048514 ! blood vessel morphogenesis
is_a: GO:0061299 ! retina vasculature morphogenesis in camera-type eye
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003501 ! retina blood vessel
relationship: results_in_morphogenesis_of UBERON:0003501 ! retina blood vessel
created_by: dph
creation_date: 2010-09-16T09:02:59Z

[Term]
id: GO:0061307
name: cardiac neural crest cell differentiation involved in heart development
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches." [GOC:dph, GOC:mtg_heart, PMID:19705442]
is_a: GO:0014033 ! neural crest cell differentiation
is_a: GO:0035051 ! cardiocyte differentiation
intersection_of: GO:0014033 ! neural crest cell differentiation
intersection_of: part_of GO:0007507 ! heart development
created_by: dph
creation_date: 2010-09-23T08:50:56Z

[Term]
id: GO:0061308
name: cardiac neural crest cell development involved in heart development
namespace: biological_process
def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart." [GOC:dph, GOC:mtg_heart]
is_a: GO:0014032 ! neural crest cell development
intersection_of: GO:0014032 ! neural crest cell development
intersection_of: part_of GO:0007507 ! heart development
relationship: part_of GO:0061307 ! cardiac neural crest cell differentiation involved in heart development
created_by: dph
creation_date: 2010-09-23T09:01:49Z

[Term]
id: GO:0061309
name: cardiac neural crest cell development involved in outflow tract morphogenesis
namespace: biological_process
def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart]
is_a: GO:0061308 ! cardiac neural crest cell development involved in heart development
intersection_of: GO:0014032 ! neural crest cell development
intersection_of: part_of GO:0003151 ! outflow tract morphogenesis
relationship: part_of GO:0003151 ! outflow tract morphogenesis
created_by: dph
creation_date: 2010-09-23T09:08:37Z

[Term]
id: GO:0061323
name: cell proliferation involved in heart morphogenesis
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: part_of GO:0003007 ! heart morphogenesis
relationship: part_of GO:0003007 ! heart morphogenesis
created_by: dph
creation_date: 2010-09-28T09:05:26Z

[Term]
id: GO:0061325
name: cell proliferation involved in outflow tract morphogenesis
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart]
is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: part_of GO:0003151 ! outflow tract morphogenesis
relationship: part_of GO:0003151 ! outflow tract morphogenesis
created_by: dph
creation_date: 2010-09-28T09:29:30Z

[Term]
id: GO:0061326
name: renal tubule development
namespace: biological_process
def: "The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10]
is_a: GO:0035295 ! tube development
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0009773 ! renal tubule
relationship: part_of GO:0072001 ! renal system development
relationship: results_in_development_of UBERON:0009773 ! renal tubule
created_by: dph
creation_date: 2010-09-28T12:50:43Z

[Term]
id: GO:0061333
name: renal tubule morphogenesis
namespace: biological_process
def: "The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10]
is_a: GO:0060562 ! epithelial tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0009773 ! renal tubule
relationship: part_of GO:0061326 ! renal tubule development
relationship: results_in_morphogenesis_of UBERON:0009773 ! renal tubule
created_by: dph
creation_date: 2010-09-28T01:43:04Z

[Term]
id: GO:0061337
name: cardiac conduction
namespace: biological_process
def: "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles." [GOC:dph]
is_a: GO:0008016 ! regulation of heart contraction
created_by: dph
creation_date: 2010-09-29T08:46:05Z

[Term]
id: GO:0061343
name: cell adhesion involved in heart morphogenesis
namespace: biological_process
def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783]
is_a: GO:0007155 ! cell adhesion
intersection_of: GO:0007155 ! cell adhesion
intersection_of: part_of GO:0003007 ! heart morphogenesis
relationship: part_of GO:0003007 ! heart morphogenesis
created_by: dph
creation_date: 2010-09-29T11:34:06Z

[Term]
id: GO:0061344
name: regulation of cell adhesion involved in heart morphogenesis
namespace: biological_process
def: "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783]
is_a: GO:0030155 ! regulation of cell adhesion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061343 ! cell adhesion involved in heart morphogenesis
relationship: regulates GO:0061343 ! cell adhesion involved in heart morphogenesis
created_by: dph
creation_date: 2010-09-29T11:35:27Z

[Term]
id: GO:0061351
name: neural precursor cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell." [GOC:dph, GOC:yaf]
is_a: GO:0008283 ! cell population proliferation
created_by: dph
creation_date: 2010-10-01T11:06:04Z

[Term]
id: GO:0061383
name: trabecula morphogenesis
namespace: biological_process
def: "The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000440 ! trabecula
relationship: results_in_morphogenesis_of UBERON:0000440 ! trabecula
created_by: dph
creation_date: 2010-12-02T08:51:45Z

[Term]
id: GO:0061384
name: heart trabecula morphogenesis
namespace: biological_process
def: "The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph]
is_a: GO:0061383 ! trabecula morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002511 ! trabecula carnea
relationship: results_in_morphogenesis_of UBERON:0002511 ! trabecula carnea
created_by: dph
creation_date: 2010-12-02T08:54:20Z

[Term]
id: GO:0061385
name: fibroblast proliferation involved in heart morphogenesis
namespace: biological_process
def: "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart." [GOC:dph]
is_a: GO:0048144 ! fibroblast proliferation
is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis
intersection_of: GO:0048144 ! fibroblast proliferation
intersection_of: part_of GO:0003007 ! heart morphogenesis
created_by: dph
creation_date: 2011-02-10T01:41:59Z

[Term]
id: GO:0061437
name: renal system vasculature development
namespace: biological_process
def: "The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195]
is_a: GO:0001944 ! vasculature development
relationship: part_of GO:0072001 ! renal system development
created_by: dph
creation_date: 2012-03-08T12:16:24Z

[Term]
id: GO:0061438
name: renal system vasculature morphogenesis
namespace: biological_process
def: "The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195]
is_a: GO:0009653 ! anatomical structure morphogenesis
relationship: part_of GO:0061437 ! renal system vasculature development
created_by: dph
creation_date: 2012-03-08T12:21:56Z

[Term]
id: GO:0061439
name: kidney vasculature morphogenesis
namespace: biological_process
def: "The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0006544 ! kidney vasculature
relationship: part_of GO:0061438 ! renal system vasculature morphogenesis
relationship: part_of GO:0061440 ! kidney vasculature development
relationship: results_in_morphogenesis_of UBERON:0006544 ! kidney vasculature
created_by: dph
creation_date: 2012-03-08T12:30:11Z

[Term]
id: GO:0061440
name: kidney vasculature development
namespace: biological_process
def: "The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195]
is_a: GO:0061437 ! renal system vasculature development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0006544 ! kidney vasculature
relationship: part_of GO:0001822 ! kidney development
relationship: results_in_development_of UBERON:0006544 ! kidney vasculature
created_by: dph
creation_date: 2012-03-08T12:39:09Z

[Term]
id: GO:0061441
name: renal artery morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood." [GOC:mtg_kidney_jan10, PMID:11891195]
is_a: GO:0048844 ! artery morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001184 ! renal artery
relationship: part_of GO:0061439 ! kidney vasculature morphogenesis
relationship: results_in_morphogenesis_of UBERON:0001184 ! renal artery
created_by: dph
creation_date: 2012-03-08T12:42:09Z

[Term]
id: GO:0061448
name: connective tissue development
namespace: biological_process
def: "The progression of a connective tissue over time, from its formation to the mature structure." [GOC:BHF]
is_a: GO:0009888 ! tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002384 ! connective tissue
relationship: results_in_development_of UBERON:0002384 ! connective tissue
created_by: dph
creation_date: 2012-03-22T12:53:41Z

[Term]
id: GO:0061450
name: trophoblast cell migration
namespace: biological_process
def: "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst." [GOC:dph]
is_a: GO:0001667 ! ameboidal-type cell migration
is_a: GO:0022414 ! reproductive process
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000351 ! trophoblast cell
relationship: part_of GO:0007566 ! embryo implantation
relationship: results_in_movement_of CL:0000351 ! trophoblast cell
created_by: dph
creation_date: 2012-07-10T08:38:37Z

[Term]
id: GO:0061453
name: interstitial cell of Cajal differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction." [GOC:dph]
synonym: "ICC differentiation" RELATED [GOC:dph]
is_a: GO:0060563 ! neuroepithelial cell differentiation
is_a: GO:0060575 ! intestinal epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0002088 ! interstitial cell of Cajal
relationship: results_in_acquisition_of_features_of CL:0002088 ! interstitial cell of Cajal
created_by: dph
creation_date: 2012-07-20T08:20:50Z

[Term]
id: GO:0061458
name: reproductive system development
namespace: biological_process
def: "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." [GOC:dph]
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000990 ! reproductive system
relationship: results_in_development_of UBERON:0000990 ! reproductive system
created_by: dph
creation_date: 2012-08-22T17:47:53Z

[Term]
id: GO:0061469
name: regulation of type B pancreatic cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation." [GOC:dph]
is_a: GO:0050678 ! regulation of epithelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0044342 ! type B pancreatic cell proliferation
relationship: regulates GO:0044342 ! type B pancreatic cell proliferation
created_by: dph
creation_date: 2012-11-01T13:16:23Z

[Term]
id: GO:0061484
name: hematopoietic stem cell homeostasis
namespace: biological_process
def: "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells." [GOC:dph, PMID:21508411]
is_a: GO:0048872 ! homeostasis of number of cells
intersection_of: GO:0048872 ! homeostasis of number of cells
intersection_of: acts_on_population_of CL:0000037 ! hematopoietic stem cell
relationship: acts_on_population_of CL:0000037 ! hematopoietic stem cell
created_by: dph
creation_date: 2012-12-04T09:41:02Z

[Term]
id: GO:0061512
name: protein localization to cilium
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a cilium." [GOC:dph]
is_a: GO:0033365 ! protein localization to organelle
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005929 ! cilium
relationship: has_target_end_location GO:0005929 ! cilium
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
property_value: RO:0002161 NCBITaxon:3176
property_value: RO:0002161 NCBITaxon:3312
property_value: RO:0002161 NCBITaxon:3378
property_value: RO:0002161 NCBITaxon:3398
property_value: RO:0002161 NCBITaxon:4890
property_value: RO:0002161 NCBITaxon:5782
created_by: dph
creation_date: 2013-03-22T15:41:44Z

[Term]
id: GO:0061515
name: myeloid cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure." [GOC:dph]
is_a: GO:0030097 ! hemopoiesis
intersection_of: GO:0048468 ! cell development
intersection_of: results_in_development_of CL:0000763 ! myeloid cell
relationship: part_of GO:0030099 ! myeloid cell differentiation
relationship: results_in_development_of CL:0000763 ! myeloid cell
created_by: dph
creation_date: 2013-04-18T13:03:16Z

[Term]
id: GO:0061523
name: cilium disassembly
namespace: biological_process
def: "A cellular process that results in the breakdown of a cilium." [GOC:cilia, GOC:dph, PMID:17604723, PMID:27350441]
comment: Note that we deem cilium and microtubule-based flagellum to be equivalent.
synonym: "cilium resorption" EXACT [GOC:dph]
is_a: GO:0044782 ! cilium organization
is_a: GO:1903008 ! organelle disassembly
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0005929 ! cilium
relationship: results_in_disassembly_of GO:0005929 ! cilium
created_by: dph
creation_date: 2013-04-18T14:59:59Z

[Term]
id: GO:0061525
name: hindgut development
namespace: biological_process
def: "The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut." [GOC:dph]
is_a: GO:0048565 ! digestive tract development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001046 ! hindgut
relationship: results_in_development_of UBERON:0001046 ! hindgut
created_by: dph
creation_date: 2013-06-14T11:22:21Z

[Term]
id: GO:0061526
name: acetylcholine secretion
namespace: biological_process
def: "The regulated release of acetylcholine by a cell." [GOC:dph]
is_a: GO:0015870 ! acetylcholine transport
is_a: GO:0023061 ! signal release
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input CHEBI:15355 ! acetylcholine
created_by: dph
creation_date: 2013-06-21T15:40:39Z

[Term]
id: GO:0061533
name: norepinephrine secretion, neurotransmission
namespace: biological_process
def: "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter." [GOC:dph]
synonym: "noradrenaline secretion, neurotransmission" EXACT [GOC:dph]
is_a: GO:0048243 ! norepinephrine secretion
is_a: GO:0160043 ! catecholamine secretion, neurotransmission
intersection_of: GO:0007269 ! neurotransmitter secretion
intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+)
created_by: dph
creation_date: 2013-06-21T16:05:08Z

[Term]
id: GO:0061548
name: ganglion development
namespace: biological_process
def: "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure." [GOC:dph]
synonym: "ganglia development" RELATED [GOC:dph]
synonym: "gangliogenesis" NARROW [GOC:BHF, GOC:rl]
is_a: GO:0009888 ! tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000045 ! ganglion
relationship: part_of GO:0007399 ! nervous system development
relationship: results_in_development_of UBERON:0000045 ! ganglion
created_by: dph
creation_date: 2013-07-10T08:36:12Z

[Term]
id: GO:0061549
name: sympathetic ganglion development
namespace: biological_process
def: "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure." [GOC:BHF, GOC:rl]
synonym: "sympathetic ganglia development" RELATED [GOC:dph]
is_a: GO:0061548 ! ganglion development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001806 ! sympathetic ganglion
relationship: part_of GO:0048485 ! sympathetic nervous system development
relationship: results_in_development_of UBERON:0001806 ! sympathetic ganglion
created_by: dph
creation_date: 2013-07-10T08:38:01Z

[Term]
id: GO:0061550
name: cranial ganglion development
namespace: biological_process
def: "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure." [GOC:dph]
synonym: "cranial ganglia development" RELATED [GOC:dph]
is_a: GO:0061548 ! ganglion development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001714 ! cranial ganglion
relationship: part_of GO:0021545 ! cranial nerve development
relationship: results_in_development_of UBERON:0001714 ! cranial ganglion
created_by: dph
creation_date: 2013-07-10T08:40:14Z

[Term]
id: GO:0061551
name: trigeminal ganglion development
namespace: biological_process
def: "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure." [GOC:dph]
synonym: "trigeminal ganglia development" RELATED [GOC:dph]
is_a: GO:0061550 ! cranial ganglion development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001675 ! trigeminal ganglion
relationship: results_in_development_of UBERON:0001675 ! trigeminal ganglion
created_by: dph
creation_date: 2013-07-10T08:42:19Z

[Term]
id: GO:0061552
name: ganglion morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of ganglion are generated and organized." [GOC:dph]
synonym: "ganglia morphogenesis" RELATED [GOC:dph]
is_a: GO:0048729 ! tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000045 ! ganglion
relationship: part_of GO:0061548 ! ganglion development
relationship: results_in_morphogenesis_of UBERON:0000045 ! ganglion
created_by: dph
creation_date: 2013-07-10T08:44:57Z

[Term]
id: GO:0061553
name: ganglion maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state." [GOC:dph]
synonym: "ganglia maturation" RELATED [GOC:dph]
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0071695 ! anatomical structure maturation
intersection_of: results_in_maturation_of UBERON:0000045 ! ganglion
relationship: part_of GO:0061548 ! ganglion development
relationship: results_in_maturation_of UBERON:0000045 ! ganglion
created_by: dph
creation_date: 2013-07-10T08:45:59Z

[Term]
id: GO:0061554
name: ganglion formation
namespace: biological_process
def: "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph]
synonym: "ganglia formation" RELATED [GOC:dph]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000045 ! ganglion
relationship: part_of GO:0061552 ! ganglion morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0000045 ! ganglion
created_by: dph
creation_date: 2013-07-10T08:51:50Z

[Term]
id: GO:0061556
name: trigeminal ganglion morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of a trigeminal ganglion is generated and organized." [GOC:dph]
synonym: "trigeminal ganglia morphogenesis" RELATED [GOC:dph]
is_a: GO:0061559 ! cranial ganglion morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001675 ! trigeminal ganglion
relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis
relationship: part_of GO:0061551 ! trigeminal ganglion development
relationship: results_in_morphogenesis_of UBERON:0001675 ! trigeminal ganglion
created_by: dph
creation_date: 2013-07-10T08:57:12Z

[Term]
id: GO:0061557
name: trigeminal ganglion maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state." [GOC:dph]
synonym: "trigeminal ganglia maturation" RELATED [GOC:dph]
is_a: GO:0061558 ! cranial ganglion maturation
intersection_of: GO:0071695 ! anatomical structure maturation
intersection_of: results_in_maturation_of UBERON:0001675 ! trigeminal ganglion
relationship: part_of GO:0021635 ! trigeminal nerve maturation
relationship: part_of GO:0061551 ! trigeminal ganglion development
relationship: results_in_maturation_of UBERON:0001675 ! trigeminal ganglion
created_by: dph
creation_date: 2013-07-10T08:58:24Z

[Term]
id: GO:0061558
name: cranial ganglion maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state." [GOC:dph]
synonym: "cranial ganglia maturation" RELATED [GOC:dph]
is_a: GO:0061553 ! ganglion maturation
intersection_of: GO:0071695 ! anatomical structure maturation
intersection_of: results_in_maturation_of UBERON:0001714 ! cranial ganglion
relationship: part_of GO:0021605 ! cranial nerve maturation
relationship: part_of GO:0061550 ! cranial ganglion development
relationship: results_in_maturation_of UBERON:0001714 ! cranial ganglion
created_by: dph
creation_date: 2013-07-10T08:59:52Z

[Term]
id: GO:0061559
name: cranial ganglion morphogenesis
namespace: biological_process
def: "The process in which the anatomical structure of a cranial ganglion is generated and organized." [GOC:dph]
synonym: "cranial ganglia morphogenesis" RELATED [GOC:dph]
is_a: GO:0061552 ! ganglion morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001714 ! cranial ganglion
relationship: part_of GO:0021602 ! cranial nerve morphogenesis
relationship: part_of GO:0061550 ! cranial ganglion development
relationship: results_in_morphogenesis_of UBERON:0001714 ! cranial ganglion
created_by: dph
creation_date: 2013-07-10T09:02:15Z

[Term]
id: GO:0061560
name: cranial ganglion formation
namespace: biological_process
def: "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph]
synonym: "cranial ganglia formation" RELATED [GOC:dph]
is_a: GO:0061554 ! ganglion formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001714 ! cranial ganglion
relationship: part_of GO:0061559 ! cranial ganglion morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001714 ! cranial ganglion
created_by: dph
creation_date: 2013-07-10T09:07:27Z

[Term]
id: GO:0061561
name: trigeminal ganglion formation
namespace: biological_process
def: "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph]
synonym: "trigeminal ganglia formation" RELATED [GOC:dph]
is_a: GO:0061560 ! cranial ganglion formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001675 ! trigeminal ganglion
relationship: part_of GO:0061556 ! trigeminal ganglion morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001675 ! trigeminal ganglion
created_by: dph
creation_date: 2013-07-10T09:08:13Z

[Term]
id: GO:0061572
name: actin filament bundle organization
namespace: biological_process
def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle." [GOC:dph]
synonym: "actin filament cable organization" RELATED [GOC:dph]
is_a: GO:0007015 ! actin filament organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0032432 ! actin filament bundle
relationship: results_in_organization_of GO:0032432 ! actin filament bundle
created_by: dph
creation_date: 2013-08-02T11:24:11Z

[Term]
id: GO:0061580
name: colon epithelial cell migration
namespace: biological_process
def: "The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph]
is_a: GO:0061582 ! intestinal epithelial cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0011108 ! colon epithelial cell
relationship: results_in_movement_of CL:0011108 ! colon epithelial cell
created_by: dph
creation_date: 2013-12-23T07:26:54Z

[Term]
id: GO:0061581
name: corneal epithelial cell migration
namespace: biological_process
def: "The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph]
is_a: GO:0010631 ! epithelial cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000575 ! corneal epithelial cell
relationship: results_in_movement_of CL:0000575 ! corneal epithelial cell
created_by: dph
creation_date: 2013-12-23T07:28:29Z

[Term]
id: GO:0061582
name: intestinal epithelial cell migration
namespace: biological_process
def: "The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph]
is_a: GO:0010631 ! epithelial cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0002563 ! intestinal epithelial cell
relationship: results_in_movement_of CL:0002563 ! intestinal epithelial cell
created_by: dph
creation_date: 2013-12-23T07:30:55Z

[Term]
id: GO:0061626
name: pharyngeal arch artery morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery." [GOC:BHF, GOC:dph, PMID:20122914]
synonym: "aortic arch artery morphogenesis" BROAD [GOC:dph]
is_a: GO:0048844 ! artery morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004363 ! pharyngeal arch artery
relationship: part_of GO:0060037 ! pharyngeal system development
relationship: results_in_morphogenesis_of UBERON:0004363 ! pharyngeal arch artery
created_by: dph
creation_date: 2014-05-09T15:34:06Z

[Term]
id: GO:0061682
name: seminal vesicle morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a seminal vesicle are generated and organized." [GOC:dph]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022612 ! gland morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000998 ! seminal vesicle
relationship: part_of GO:0061107 ! seminal vesicle development
relationship: results_in_morphogenesis_of UBERON:0000998 ! seminal vesicle
created_by: dph
creation_date: 2015-03-04T13:33:49Z

[Term]
id: GO:0061683
name: branching involved in seminal vesicle morphogenesis
namespace: biological_process
def: "The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph, PMID:16916376]
synonym: "gonecyst branching morphogenesis" EXACT [GOC:dph]
synonym: "seminal gland branching morphogenesis" EXACT [GOC:dph]
synonym: "seminal vesicle branching" EXACT [GOC:dph]
synonym: "seminal vesicle branching morphogenesis" EXACT [GOC:dph]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0061138 ! morphogenesis of a branching epithelium
intersection_of: GO:0061138 ! morphogenesis of a branching epithelium
intersection_of: part_of GO:0061682 ! seminal vesicle morphogenesis
relationship: part_of GO:0061108 ! seminal vesicle epithelium development
relationship: part_of GO:0061682 ! seminal vesicle morphogenesis
created_by: dph
creation_date: 2015-03-04T13:39:47Z

[Term]
id: GO:0061687
name: detoxification of inorganic compound
namespace: biological_process
def: "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds." [GOC:vw]
is_a: GO:0098754 ! detoxification
intersection_of: GO:0098754 ! detoxification
intersection_of: has_primary_input CHEBI:24835 ! inorganic molecular entity
relationship: has_primary_input CHEBI:24835 ! inorganic molecular entity
created_by: dph
creation_date: 2015-03-09T09:16:23Z

[Term]
id: GO:0061695
name: transferase complex, transferring phosphorus-containing groups
namespace: cellular_component
def: "A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:bhm, GOC:dph]
is_a: GO:1990234 ! transferase complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: capable_of GO:0016772 ! transferase activity, transferring phosphorus-containing groups
relationship: capable_of GO:0016772 ! transferase activity, transferring phosphorus-containing groups
created_by: dph
creation_date: 2015-05-06T11:22:38Z

[Term]
id: GO:0061792
name: secretory granule maturation
namespace: biological_process
def: "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling." [GOC:bf, GOC:dph, GOC:PARL, PMID:16618809]
is_a: GO:0033363 ! secretory granule organization
is_a: GO:0071695 ! anatomical structure maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of GO:0030141 ! secretory granule
relationship: results_in_maturation_of GO:0030141 ! secretory granule
created_by: dph
creation_date: 2016-09-09T13:24:34Z

[Term]
id: GO:0061853
name: regulation of neuroblast migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neuroblast migration." [PMID:23149556]
is_a: GO:0030334 ! regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097402 ! neuroblast migration
relationship: regulates GO:0097402 ! neuroblast migration
created_by: dph
creation_date: 2017-03-08T18:17:07Z

[Term]
id: GO:0061854
name: positive regulation of neuroblast migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuroblast migration." [PMID:23149556]
is_a: GO:0030335 ! positive regulation of cell migration
is_a: GO:0061853 ! regulation of neuroblast migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097402 ! neuroblast migration
relationship: positively_regulates GO:0097402 ! neuroblast migration
created_by: dph
creation_date: 2017-03-08T18:22:30Z

[Term]
id: GO:0061855
name: negative regulation of neuroblast migration
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration." [PMID:23149556]
is_a: GO:0030336 ! negative regulation of cell migration
is_a: GO:0061853 ! regulation of neuroblast migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097402 ! neuroblast migration
relationship: negatively_regulates GO:0097402 ! neuroblast migration
created_by: dph
creation_date: 2017-03-08T18:26:21Z

[Term]
id: GO:0061900
name: glial cell activation
namespace: biological_process
def: "A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:aruk, GOC:bc, PMID:18723082]
is_a: GO:0001775 ! cell activation
intersection_of: GO:0001775 ! cell activation
intersection_of: has_primary_input CL:0000125 ! glial cell
relationship: has_primary_input CL:0000125 ! glial cell
relationship: part_of GO:0150076 ! neuroinflammatory response
created_by: dph
creation_date: 2017-06-13T13:06:23Z

[Term]
id: GO:0061938
name: protein localization to somatodendritic compartment
namespace: biological_process
def: "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment." [PMID:18341993]
synonym: "somatodendritic protein localization" EXACT []
is_a: GO:0008104 ! protein localization
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0036477 ! somatodendritic compartment
relationship: has_target_end_location GO:0036477 ! somatodendritic compartment
created_by: dph
creation_date: 2017-09-08T13:22:26Z

[Term]
id: GO:0061951
name: establishment of protein localization to plasma membrane
namespace: biological_process
def: "The directed movement of a protein to a specific location in a plasma membrane." [GOC:dph, GOC:vw]
is_a: GO:0090150 ! establishment of protein localization to membrane
intersection_of: GO:0045184 ! establishment of protein localization
intersection_of: has_target_end_location GO:0005886 ! plasma membrane
intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure
relationship: has_target_end_location GO:0005886 ! plasma membrane
relationship: has_target_start_location GO:0005622 ! intracellular anatomical structure
created_by: dph
creation_date: 2017-10-26T12:55:15Z

[Term]
id: GO:0061971
name: replacement bone morphogenesis
namespace: biological_process
def: "The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone." [PMID:29852585]
is_a: GO:0060349 ! bone morphogenesis
intersection_of: GO:0060349 ! bone morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0012075 ! replacement bone
relationship: results_in_morphogenesis_of UBERON:0012075 ! replacement bone
created_by: dph
creation_date: 2018-02-12T18:10:59Z

[Term]
id: GO:0061972
name: dermal bone morphogenesis
namespace: biological_process
def: "The process in which bone which forms superficially in the organism are generated and organized." [PMID:12588850, PMID:15003632]
is_a: GO:0061973 ! membrane bone morphogenesis
intersection_of: GO:0060349 ! bone morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0008907 ! dermal bone
relationship: results_in_morphogenesis_of UBERON:0008907 ! dermal bone
created_by: dph
creation_date: 2018-02-12T18:16:21Z

[Term]
id: GO:0061973
name: membrane bone morphogenesis
namespace: biological_process
def: "The process in which bone which forms deep in the organism are generated and organized." [PMID:14579374]
is_a: GO:0060349 ! bone morphogenesis
intersection_of: GO:0060349 ! bone morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0007842 ! membrane bone
relationship: results_in_morphogenesis_of UBERON:0007842 ! membrane bone
created_by: dph
creation_date: 2018-02-12T18:21:09Z

[Term]
id: GO:0061983
name: meiosis II cell cycle process
namespace: biological_process
def: "A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes." [PMID:29385397]
synonym: "second meiotic division" EXACT [PMID:29385397]
is_a: GO:1903046 ! meiotic cell cycle process
created_by: dph
creation_date: 2018-02-14T22:37:44Z

[Term]
id: GO:0062012
name: regulation of small molecule metabolic process
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of a small molecule metabolic process." [GOC:vw]
synonym: "regulation of small molecule metabolism" EXACT []
is_a: GO:0019222 ! regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0044281 ! small molecule metabolic process
relationship: regulates GO:0044281 ! small molecule metabolic process
created_by: dph
creation_date: 2018-03-19T14:11:54Z

[Term]
id: GO:0062013
name: positive regulation of small molecule metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process." [GOC:vw]
synonym: "positive regulation of small molecule metabolism" EXACT []
is_a: GO:0009893 ! positive regulation of metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0044281 ! small molecule metabolic process
relationship: positively_regulates GO:0044281 ! small molecule metabolic process
created_by: dph
creation_date: 2018-03-19T14:25:10Z

[Term]
id: GO:0062014
name: negative regulation of small molecule metabolic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process." [GOC:vw]
synonym: "negative regulation of small molecule metabolism" EXACT []
is_a: GO:0009892 ! negative regulation of metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0044281 ! small molecule metabolic process
relationship: negatively_regulates GO:0044281 ! small molecule metabolic process
created_by: dph
creation_date: 2018-03-19T14:27:23Z

[Term]
id: GO:0062023
name: collagen-containing extracellular matrix
namespace: cellular_component
def: "An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells." [GOC:BHF, GOC:rph, PMID:21123617]
is_a: GO:0031012 ! extracellular matrix
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
created_by: dph
creation_date: 2018-04-13T12:47:21Z

[Term]
id: GO:0062033
name: positive regulation of mitotic sister chromatid segregation
namespace: biological_process
def: "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis." [PMID:12773390]
is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation
is_a: GO:0051984 ! positive regulation of chromosome segregation
is_a: GO:2001252 ! positive regulation of chromosome organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0000070 ! mitotic sister chromatid segregation
relationship: positively_regulates GO:0000070 ! mitotic sister chromatid segregation
created_by: dph
creation_date: 2018-04-23T14:32:23Z

[Term]
id: GO:0062094
name: stomach development
namespace: biological_process
def: "The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ." [PMID:11967278]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000945 ! stomach
relationship: part_of GO:0048565 ! digestive tract development
relationship: results_in_development_of UBERON:0000945 ! stomach
created_by: dph
creation_date: 2018-11-20T18:15:45Z

[Term]
id: GO:0062149
name: detection of stimulus involved in sensory perception of pain
namespace: biological_process
def: "The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal." [PMID:19837031]
is_a: GO:0050906 ! detection of stimulus involved in sensory perception
intersection_of: GO:0051606 ! detection of stimulus
intersection_of: part_of GO:0019233 ! sensory perception of pain
relationship: part_of GO:0019233 ! sensory perception of pain
created_by: dph
creation_date: 2019-09-13T13:48:47Z

[Term]
id: GO:0062223
name: regulation of somatic muscle development
namespace: biological_process
def: "Any process that regulates the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007525 ! somatic muscle development
relationship: regulates GO:0007525 ! somatic muscle development
created_by: dph
creation_date: 2020-03-13T18:58:37Z

[Term]
id: GO:0062224
name: positive regulation of somatic muscle development
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0062223 ! regulation of somatic muscle development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007525 ! somatic muscle development
relationship: positively_regulates GO:0007525 ! somatic muscle development
created_by: dph
creation_date: 2020-03-13T19:03:38Z

[Term]
id: GO:0062225
name: negative regulation of somatic muscle development
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of somatic muscle development." [PMID:16643882, PMID:25758712]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0062223 ! regulation of somatic muscle development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007525 ! somatic muscle development
relationship: negatively_regulates GO:0007525 ! somatic muscle development
created_by: dph
creation_date: 2020-03-13T19:06:27Z

[Term]
id: GO:0062237
name: protein localization to postsynapse
namespace: biological_process
def: "Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell." [PMID:31189538]
is_a: GO:0035418 ! protein localization to synapse
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0098794 ! postsynapse
relationship: has_target_end_location GO:0098794 ! postsynapse
created_by: dph
creation_date: 2020-04-20T13:58:43Z

[Term]
id: GO:0065002
name: intracellular protein transmembrane transport
namespace: biological_process
def: "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore." [GOC:isa_complete]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "intracellular membrane translocation of a protein" EXACT []
synonym: "intracellular protein membrane transport" EXACT []
synonym: "intracellular protein transport across a membrane" EXACT []
is_a: GO:0006886 ! intracellular protein transport
is_a: GO:0071806 ! protein transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input PR:000000001 ! protein
intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure
intersection_of: results_in_transport_across GO:0016020 ! membrane

[Term]
id: GO:0065003
name: protein-containing complex assembly
namespace: biological_process
alt_id: GO:0006461
alt_id: GO:0034622
alt_id: GO:0043623
def: "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." [GOC:jl]
subset: goslim_chembl
subset: goslim_drosophila
subset: goslim_generic
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_pombe
subset: goslim_prokaryote
synonym: "cellular macromolecule complex assembly" RELATED []
synonym: "cellular protein complex assembly" EXACT []
synonym: "cellular protein-containing complex assembly" RELATED []
synonym: "chaperone activity" RELATED []
synonym: "macromolecular complex assembly" RELATED []
synonym: "macromolecule complex assembly" RELATED []
synonym: "protein complex assembly" RELATED []
synonym: "protein complex formation" RELATED []
is_a: GO:0022607 ! cellular component assembly
is_a: GO:0043933 ! protein-containing complex organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0032991 ! protein-containing complex
relationship: results_in_assembly_of GO:0032991 ! protein-containing complex
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI

[Term]
id: GO:0065004
name: protein-DNA complex assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex." [GOC:jl]
synonym: "DNA-protein complex assembly" EXACT [GOC:mah]
is_a: GO:0065003 ! protein-containing complex assembly
is_a: GO:0071824 ! protein-DNA complex organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0032993 ! protein-DNA complex
relationship: results_in_assembly_of GO:0032993 ! protein-DNA complex

[Term]
id: GO:0065007
name: biological regulation
namespace: biological_process
def: "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]
subset: gocheck_do_not_annotate
subset: goslim_pir
synonym: "regulation" BROAD []
is_a: GO:0008150 ! biological process

[Term]
id: GO:0065008
name: regulation of biological quality
namespace: biological_process
def: "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]
subset: goslim_pir
synonym: "regulation of biological attribute" EXACT []
synonym: "regulation of biological characteristic" EXACT []
is_a: GO:0065007 ! biological regulation

[Term]
id: GO:0065009
name: regulation of molecular function
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete]
subset: gocheck_do_not_annotate
subset: goslim_pir
subset: goslim_plant
synonym: "regulation of a molecular function" EXACT []
is_a: GO:0065007 ! biological regulation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003674 ! molecular_function
relationship: regulates GO:0003674 ! molecular_function

[Term]
id: GO:0065010
name: extracellular membrane-bounded organelle
namespace: cellular_component
def: "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:isa_complete]
synonym: "extracellular membrane-enclosed organelle" EXACT []
is_a: GO:0043227 ! membrane-bounded organelle
is_a: GO:0043230 ! extracellular organelle
intersection_of: GO:0043227 ! membrane-bounded organelle
intersection_of: part_of GO:0005576 ! extracellular region

[Term]
id: GO:0070013
name: intracellular organelle lumen
namespace: cellular_component
def: "An organelle lumen that is part of an intracellular organelle." [GOC:mah]
is_a: GO:0043233 ! organelle lumen
intersection_of: GO:0031974 ! membrane-enclosed lumen
intersection_of: part_of GO:0043229 ! intracellular organelle
relationship: part_of GO:0043229 ! intracellular organelle

[Term]
id: GO:0070050
name: neuron cellular homeostasis
namespace: biological_process
def: "The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state." [GOC:BHF, GOC:mah]
synonym: "neuron maintenance" EXACT []
is_a: GO:0019725 ! cellular homeostasis
intersection_of: GO:0019725 ! cellular homeostasis
intersection_of: occurs_in CL:0000540 ! neuron
relationship: occurs_in CL:0000540 ! neuron
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI

[Term]
id: GO:0070062
name: extracellular exosome
namespace: cellular_component
def: "A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm." [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]
synonym: "exosome" EXACT [GOC:pr]
synonym: "extracellular vesicular exosome" EXACT [GOC:vesicles]
is_a: GO:1903561 ! extracellular vesicle
relationship: part_of GO:0005615 ! extracellular space

[Term]
id: GO:0070091
name: glucagon secretion
namespace: biological_process
def: "The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)." [GOC:BHF, GOC:rl]
is_a: GO:0030072 ! peptide hormone secretion
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input CHEBI:5391 ! glucagon
relationship: has_primary_input CHEBI:5391 ! glucagon

[Term]
id: GO:0070092
name: regulation of glucagon secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah]
is_a: GO:0090276 ! regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070091 ! glucagon secretion
relationship: regulates GO:0070091 ! glucagon secretion

[Term]
id: GO:0070093
name: negative regulation of glucagon secretion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah]
synonym: "down regulation of glucagon secretion" EXACT []
synonym: "down-regulation of glucagon secretion" EXACT []
synonym: "downregulation of glucagon secretion" EXACT []
synonym: "inhibition of glucagon secretion" NARROW []
is_a: GO:0070092 ! regulation of glucagon secretion
is_a: GO:0090278 ! negative regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0070091 ! glucagon secretion
relationship: negatively_regulates GO:0070091 ! glucagon secretion

[Term]
id: GO:0070094
name: positive regulation of glucagon secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah]
synonym: "activation of glucagon secretion" NARROW []
synonym: "stimulation of glucagon secretion" NARROW []
synonym: "up regulation of glucagon secretion" EXACT []
synonym: "up-regulation of glucagon secretion" EXACT []
synonym: "upregulation of glucagon secretion" EXACT []
is_a: GO:0070092 ! regulation of glucagon secretion
is_a: GO:0090277 ! positive regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0070091 ! glucagon secretion
relationship: positively_regulates GO:0070091 ! glucagon secretion

[Term]
id: GO:0070161
name: anchoring junction
namespace: cellular_component
def: "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." [ISBN:0815332181]
synonym: "anchoring cell junction" EXACT [GOC:mah]
is_a: GO:0030054 ! cell junction

[Term]
id: GO:0070192
name: chromosome organization involved in meiotic cell cycle
namespace: biological_process
def: "A process of chromosome organization that is involved in a meiotic cell cycle." [GOC:mah]
synonym: "chromosome organisation involved in meiosis" EXACT [GOC:mah]
synonym: "meiotic chromosome organization" EXACT [GOC:mah]
is_a: GO:0051276 ! chromosome organization
is_a: GO:1903046 ! meiotic cell cycle process
intersection_of: GO:0051276 ! chromosome organization
intersection_of: part_of GO:0051321 ! meiotic cell cycle

[Term]
id: GO:0070199
name: establishment of protein localization to chromosome
namespace: biological_process
def: "The directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah]
synonym: "establishment of protein localisation to chromosome" EXACT [GOC:mah]
is_a: GO:0072594 ! establishment of protein localization to organelle
intersection_of: GO:0045184 ! establishment of protein localization
intersection_of: has_target_end_location GO:0005694 ! chromosome
relationship: has_target_end_location GO:0005694 ! chromosome

[Term]
id: GO:0070201
name: regulation of establishment of protein localization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." [GOC:BHF, GOC:mah]
synonym: "regulation of establishment of protein localisation" EXACT [GOC:mah]
is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0045184 ! establishment of protein localization
relationship: regulates GO:0045184 ! establishment of protein localization

[Term]
id: GO:0070202
name: regulation of establishment of protein localization to chromosome
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah]
synonym: "regulation of establishment of protein localisation to chromosome" EXACT [GOC:mah]
is_a: GO:0070201 ! regulation of establishment of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070199 ! establishment of protein localization to chromosome
relationship: regulates GO:0070199 ! establishment of protein localization to chromosome

[Term]
id: GO:0070227
name: lymphocyte apoptotic process
namespace: biological_process
def: "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]
comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).
synonym: "lymphocyte apoptosis" NARROW []
is_a: GO:0071887 ! leukocyte apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000542 ! lymphocyte
relationship: occurs_in CL:0000542 ! lymphocyte

[Term]
id: GO:0070228
name: regulation of lymphocyte apoptotic process
namespace: biological_process
def: "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]
comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).
synonym: "regulation of lymphocyte apoptosis" NARROW []
is_a: GO:2000106 ! regulation of leukocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070227 ! lymphocyte apoptotic process
relationship: regulates GO:0070227 ! lymphocyte apoptotic process

[Term]
id: GO:0070229
name: negative regulation of lymphocyte apoptotic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]
comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).
synonym: "down regulation of lymphocyte apoptosis" EXACT [GOC:add]
synonym: "down-regulation of lymphocyte apoptosis" EXACT [GOC:add]
synonym: "downregulation of lymphocyte apoptosis" EXACT [GOC:add]
synonym: "inhibition of lymphocyte apoptosis" NARROW [GOC:add]
synonym: "negative regulation of lymphocyte apoptosis" NARROW []
is_a: GO:0070228 ! regulation of lymphocyte apoptotic process
is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0070227 ! lymphocyte apoptotic process
relationship: negatively_regulates GO:0070227 ! lymphocyte apoptotic process

[Term]
id: GO:0070230
name: positive regulation of lymphocyte apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]
comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).
synonym: "activation of lymphocyte apoptosis" NARROW [GOC:add]
synonym: "positive regulation of lymphocyte apoptosis" NARROW []
synonym: "stimulation of lymphocyte apoptosis" NARROW [GOC:add]
synonym: "up regulation of lymphocyte apoptosis" EXACT [GOC:add]
synonym: "up-regulation of lymphocyte apoptosis" EXACT [GOC:add]
synonym: "upregulation of lymphocyte apoptosis" EXACT [GOC:add]
is_a: GO:0070228 ! regulation of lymphocyte apoptotic process
is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0070227 ! lymphocyte apoptotic process
relationship: positively_regulates GO:0070227 ! lymphocyte apoptotic process

[Term]
id: GO:0070231
name: T cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [CL:0000084, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]
synonym: "programmed cell death of T cells by apoptosis" EXACT [GOC:add]
synonym: "T cell apoptosis" NARROW []
synonym: "T lymphocyte apoptosis" EXACT [GOC:add]
synonym: "T-cell apoptosis" EXACT [GOC:add]
synonym: "T-lymphocyte apoptosis" EXACT [GOC:add]
is_a: GO:0070227 ! lymphocyte apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000084 ! T cell
relationship: occurs_in CL:0000084 ! T cell

[Term]
id: GO:0070232
name: regulation of T cell apoptotic process
namespace: biological_process
def: "Any process that modulates the occurrence or rate of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]
synonym: "regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add]
synonym: "regulation of T cell apoptosis" NARROW []
synonym: "regulation of T lymphocyte apoptosis" EXACT [GOC:add]
synonym: "regulation of T-cell apoptosis" EXACT [GOC:add]
synonym: "regulation of T-lymphocyte apoptosis" EXACT [GOC:add]
is_a: GO:0070228 ! regulation of lymphocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070231 ! T cell apoptotic process
relationship: regulates GO:0070231 ! T cell apoptotic process

[Term]
id: GO:0070233
name: negative regulation of T cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]
synonym: "down regulation of T cell apoptosis" EXACT [GOC:add]
synonym: "down-regulation of T cell apoptosis" EXACT [GOC:add]
synonym: "downregulation of T cell apoptosis" EXACT [GOC:add]
synonym: "inhibition of T cell apoptosis" NARROW [GOC:add]
synonym: "negative regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add]
synonym: "negative regulation of T cell apoptosis" NARROW []
synonym: "negative regulation of T lymphocyte apoptosis" EXACT [GOC:add]
synonym: "negative regulation of T-cell apoptosis" EXACT [GOC:add]
synonym: "negative regulation of T-lymphocyte apoptosis" EXACT [GOC:add]
is_a: GO:0070229 ! negative regulation of lymphocyte apoptotic process
is_a: GO:0070232 ! regulation of T cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0070231 ! T cell apoptotic process
relationship: negatively_regulates GO:0070231 ! T cell apoptotic process

[Term]
id: GO:0070234
name: positive regulation of T cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]
synonym: "activation of T cell apoptosis" NARROW [GOC:add]
synonym: "positive regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add]
synonym: "positive regulation of T cell apoptosis" NARROW []
synonym: "positive regulation of T lymphocyte apoptosis" EXACT [GOC:add]
synonym: "positive regulation of T-cell apoptosis" EXACT [GOC:add]
synonym: "positive regulation of T-lymphocyte apoptosis" EXACT [GOC:add]
synonym: "stimulation of T cell apoptosis" NARROW [GOC:add]
synonym: "up regulation of T cell apoptosis" EXACT [GOC:add]
synonym: "up-regulation of T cell apoptosis" EXACT [GOC:add]
synonym: "upregulation of T cell apoptosis" EXACT [GOC:add]
is_a: GO:0070230 ! positive regulation of lymphocyte apoptotic process
is_a: GO:0070232 ! regulation of T cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0070231 ! T cell apoptotic process
relationship: positively_regulates GO:0070231 ! T cell apoptotic process

[Term]
id: GO:0070253
name: somatostatin secretion
namespace: biological_process
def: "The regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:mah]
is_a: GO:0030072 ! peptide hormone secretion
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input CHEBI:64628 ! somatostatin
relationship: has_primary_input CHEBI:64628 ! somatostatin

[Term]
id: GO:0070254
name: mucus secretion
namespace: biological_process
def: "The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function." [GOC:add, ISBN:068340007X, ISBN:0721662544]
synonym: "mucus production" EXACT [GOC:add]
is_a: GO:0007589 ! body fluid secretion
is_a: GO:0032941 ! secretion by tissue
intersection_of: GO:0046903 ! secretion
intersection_of: has_primary_input UBERON:0000912 ! mucus
relationship: has_primary_input UBERON:0000912 ! mucus

[Term]
id: GO:0070255
name: regulation of mucus secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add]
synonym: "regulation of mucus production" EXACT [GOC:add]
is_a: GO:0050878 ! regulation of body fluid levels
is_a: GO:0051046 ! regulation of secretion
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070254 ! mucus secretion
relationship: regulates GO:0070254 ! mucus secretion

[Term]
id: GO:0070256
name: negative regulation of mucus secretion
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add]
synonym: "negative regulation of mucus production" EXACT [GOC:add]
is_a: GO:0051048 ! negative regulation of secretion
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0070255 ! regulation of mucus secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0070254 ! mucus secretion
relationship: negatively_regulates GO:0070254 ! mucus secretion

[Term]
id: GO:0070257
name: positive regulation of mucus secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add]
synonym: "positive regulation of mucus production" EXACT [GOC:add]
is_a: GO:0051047 ! positive regulation of secretion
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:0070255 ! regulation of mucus secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0070254 ! mucus secretion
relationship: positively_regulates GO:0070254 ! mucus secretion

[Term]
id: GO:0070285
name: pigment cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate." [GOC:cvs]
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0000147 ! pigment cell
relationship: part_of GO:0050931 ! pigment cell differentiation
relationship: results_in_development_of CL:0000147 ! pigment cell

[Term]
id: GO:0070341
name: fat cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat." [GOC:mah, GOC:sl]
synonym: "adipocyte proliferation" EXACT [GOC:sl]
synonym: "adipose cell proliferation" EXACT [GOC:sl]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000136 ! adipocyte
relationship: acts_on_population_of CL:0000136 ! adipocyte

[Term]
id: GO:0070344
name: regulation of fat cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of fat cell proliferation." [GOC:mah, GOC:sl]
synonym: "regulation of adipocyte proliferation" EXACT [GOC:sl]
synonym: "regulation of adipose cell proliferation" EXACT [GOC:sl]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070341 ! fat cell proliferation
relationship: regulates GO:0070341 ! fat cell proliferation

[Term]
id: GO:0070345
name: negative regulation of fat cell proliferation
namespace: biological_process
def: "Any process that stops or decreases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl]
synonym: "down regulation of fat cell proliferation" EXACT [GOC:mah]
synonym: "down-regulation of fat cell proliferation" EXACT [GOC:mah]
synonym: "downregulation of fat cell proliferation" EXACT [GOC:mah]
synonym: "inhibition of fat cell proliferation" NARROW [GOC:mah]
synonym: "negative regulation of adipocyte proliferation" EXACT [GOC:sl]
synonym: "negative regulation of adipose cell proliferation" EXACT [GOC:sl]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0070344 ! regulation of fat cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0070341 ! fat cell proliferation
relationship: negatively_regulates GO:0070341 ! fat cell proliferation

[Term]
id: GO:0070346
name: positive regulation of fat cell proliferation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl]
synonym: "activation of fat cell proliferation" NARROW [GOC:mah]
synonym: "positive regulation of adipocyte proliferation" EXACT [GOC:sl]
synonym: "positive regulation of adipose cell proliferation" EXACT [GOC:sl]
synonym: "stimulation of fat cell proliferation" NARROW [GOC:mah]
synonym: "up regulation of fat cell proliferation" EXACT [GOC:mah]
synonym: "up-regulation of fat cell proliferation" EXACT [GOC:mah]
synonym: "upregulation of fat cell proliferation" EXACT [GOC:mah]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0070344 ! regulation of fat cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0070341 ! fat cell proliferation
relationship: positively_regulates GO:0070341 ! fat cell proliferation

[Term]
id: GO:0070365
name: hepatocyte differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver." [CL:0000182, PMID:7588884]
synonym: "liver cell differentiation" EXACT [GOC:mah]
is_a: GO:0030855 ! epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000182 ! hepatocyte
relationship: part_of GO:0001889 ! liver development
relationship: results_in_acquisition_of_features_of CL:0000182 ! hepatocyte

[Term]
id: GO:0070366
name: regulation of hepatocyte differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl]
synonym: "regulation of liver cell differentiation" EXACT [GOC:sl]
is_a: GO:0030856 ! regulation of epithelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070365 ! hepatocyte differentiation
relationship: regulates GO:0070365 ! hepatocyte differentiation

[Term]
id: GO:0070367
name: negative regulation of hepatocyte differentiation
namespace: biological_process
def: "Any process that stops or decreases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl]
synonym: "down regulation of hepatocyte differentiation" EXACT [GOC:mah]
synonym: "down-regulation of hepatocyte differentiation" EXACT [GOC:mah]
synonym: "downregulation of hepatocyte differentiation" EXACT [GOC:mah]
synonym: "inhibition of hepatocyte differentiation" NARROW [GOC:mah]
synonym: "negative regulation of liver cell differentiation" EXACT [GOC:sl]
is_a: GO:0030857 ! negative regulation of epithelial cell differentiation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0070366 ! regulation of hepatocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0070365 ! hepatocyte differentiation
relationship: negatively_regulates GO:0070365 ! hepatocyte differentiation

[Term]
id: GO:0070368
name: positive regulation of hepatocyte differentiation
namespace: biological_process
def: "Any process that activates or increases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl]
synonym: "activation of hepatocyte differentiation" NARROW [GOC:mah]
synonym: "positive regulation of liver cell differentiation" EXACT [GOC:sl]
synonym: "stimulation of hepatocyte differentiation" NARROW [GOC:mah]
synonym: "up regulation of hepatocyte differentiation" EXACT [GOC:mah]
synonym: "up-regulation of hepatocyte differentiation" EXACT [GOC:mah]
synonym: "upregulation of hepatocyte differentiation" EXACT [GOC:mah]
is_a: GO:0030858 ! positive regulation of epithelial cell differentiation
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:0070366 ! regulation of hepatocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0070365 ! hepatocyte differentiation
relationship: positively_regulates GO:0070365 ! hepatocyte differentiation

[Term]
id: GO:0070382
name: exocytic vesicle
namespace: cellular_component
def: "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah]
synonym: "exocytic constitutive secretory pathway transport vesicle" EXACT []
synonym: "exocytotic vesicle" EXACT [GOC:kad]
is_a: GO:0030133 ! transport vesicle
is_a: GO:0099503 ! secretory vesicle
intersection_of: GO:0030133 ! transport vesicle
intersection_of: capable_of GO:0099500 ! vesicle fusion to plasma membrane

[Term]
id: GO:0070482
name: response to oxygen levels
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen." [GOC:BHF, GOC:mah]
is_a: GO:0009628 ! response to abiotic stimulus

[Term]
id: GO:0070483
name: detection of hypoxia
namespace: biological_process
def: "The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:BHF, GOC:mah]
synonym: "detection of reduced oxygen levels" EXACT [GOC:vk]
is_a: GO:0001666 ! response to hypoxia
is_a: GO:0003032 ! detection of oxygen

[Term]
id: GO:0070507
name: regulation of microtubule cytoskeleton organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah]
synonym: "regulation of microtubule cytoskeleton organisation" EXACT [GOC:mah]
synonym: "regulation of microtubule dynamics" EXACT [GOC:dph, GOC:tb]
is_a: GO:0032886 ! regulation of microtubule-based process
is_a: GO:0051493 ! regulation of cytoskeleton organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0000226 ! microtubule cytoskeleton organization
relationship: regulates GO:0000226 ! microtubule cytoskeleton organization

[Term]
id: GO:0070633
name: transepithelial transport
namespace: biological_process
def: "The directed movement of a substance from one side of an epithelium to the other." [GOC:mah, GOC:yaf, ISBN:0716731363]
is_a: GO:0006810 ! transport
intersection_of: GO:0006810 ! transport
intersection_of: results_in_transport_across UBERON:0000483 ! epithelium
relationship: results_in_transport_across UBERON:0000483 ! epithelium
created_by: mah
creation_date: 2009-05-06T03:31:02Z

[Term]
id: GO:0070634
name: transepithelial ammonium transport
namespace: biological_process
def: "The directed movement of ammonium ions from one side of an epithelium to the other." [GOC:mah, GOC:yaf]
is_a: GO:0070633 ! transepithelial transport
is_a: GO:0071705 ! nitrogen compound transport
intersection_of: GO:0070633 ! transepithelial transport
intersection_of: has_primary_input CHEBI:28938 ! ammonium
relationship: has_primary_input CHEBI:28938 ! ammonium
created_by: mah
creation_date: 2009-05-06T03:34:43Z

[Term]
id: GO:0070661
name: leukocyte proliferation
namespace: biological_process
def: "The expansion of a leukocyte population by cell division." [GOC:add]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000738 ! leukocyte
relationship: acts_on_population_of CL:0000738 ! leukocyte
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
created_by: mah
creation_date: 2009-05-28T05:25:28Z

[Term]
id: GO:0070663
name: regulation of leukocyte proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070661 ! leukocyte proliferation
relationship: regulates GO:0070661 ! leukocyte proliferation
created_by: mah
creation_date: 2009-05-28T05:30:39Z

[Term]
id: GO:0070664
name: negative regulation of leukocyte proliferation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah]
synonym: "down regulation of leukocyte proliferation" EXACT [GOC:mah]
synonym: "down-regulation of leukocyte proliferation" EXACT [GOC:mah]
synonym: "downregulation of leukocyte proliferation" EXACT [GOC:mah]
synonym: "inhibition of leukocyte proliferation" NARROW [GOC:mah]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0070663 ! regulation of leukocyte proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0070661 ! leukocyte proliferation
relationship: negatively_regulates GO:0070661 ! leukocyte proliferation
created_by: mah
creation_date: 2009-05-28T05:34:50Z

[Term]
id: GO:0070665
name: positive regulation of leukocyte proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah]
synonym: "activation of leukocyte proliferation" NARROW [GOC:mah]
synonym: "stimulation of leukocyte proliferation" NARROW [GOC:mah]
synonym: "up regulation of leukocyte proliferation" EXACT [GOC:mah]
synonym: "up-regulation of leukocyte proliferation" EXACT [GOC:mah]
synonym: "upregulation of leukocyte proliferation" EXACT [GOC:mah]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0070663 ! regulation of leukocyte proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0070661 ! leukocyte proliferation
relationship: positively_regulates GO:0070661 ! leukocyte proliferation
created_by: mah
creation_date: 2009-05-28T05:36:46Z

[Term]
id: GO:0070727
name: cellular macromolecule localization
namespace: biological_process
def: "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." [GOC:mah]
synonym: "cellular macromolecule localisation" EXACT [GOC:mah]
is_a: GO:0033036 ! macromolecule localization
is_a: GO:0051641 ! cellular localization
created_by: mah
creation_date: 2009-06-16T04:08:29Z

[Term]
id: GO:0070831
name: basement membrane assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue." [GOC:mah]
comment: Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer.
is_a: GO:0071711 ! basement membrane organization
is_a: GO:0085029 ! extracellular matrix assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0005604 ! basement membrane
relationship: results_in_assembly_of GO:0005604 ! basement membrane
created_by: mah
creation_date: 2009-07-23T05:01:51Z

[Term]
id: GO:0070857
name: regulation of bile acid biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah]
synonym: "regulation of bile acid anabolism" EXACT [GOC:mah]
synonym: "regulation of bile acid biosynthesis" EXACT [GOC:mah]
synonym: "regulation of bile acid formation" EXACT [GOC:mah]
synonym: "regulation of bile acid synthesis" EXACT [GOC:mah]
is_a: GO:0010565 ! regulation of cellular ketone metabolic process
is_a: GO:0031326 ! regulation of cellular biosynthetic process
is_a: GO:0050810 ! regulation of steroid biosynthetic process
is_a: GO:1904251 ! regulation of bile acid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006699 ! bile acid biosynthetic process
relationship: regulates GO:0006699 ! bile acid biosynthetic process
created_by: mah
creation_date: 2009-08-14T03:09:02Z

[Term]
id: GO:0070858
name: negative regulation of bile acid biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah]
synonym: "down regulation of bile acid biosynthetic process" EXACT [GOC:mah]
synonym: "down-regulation of bile acid biosynthetic process" EXACT [GOC:mah]
synonym: "downregulation of bile acid biosynthetic process" EXACT [GOC:mah]
synonym: "inhibition of bile acid biosynthetic process" NARROW [GOC:mah]
synonym: "negative regulation of bile acid anabolism" EXACT [GOC:mah]
synonym: "negative regulation of bile acid biosynthesis" EXACT [GOC:mah]
synonym: "negative regulation of bile acid formation" EXACT [GOC:mah]
synonym: "negative regulation of bile acid synthesis" EXACT [GOC:mah]
is_a: GO:0010894 ! negative regulation of steroid biosynthetic process
is_a: GO:0031327 ! negative regulation of cellular biosynthetic process
is_a: GO:0070857 ! regulation of bile acid biosynthetic process
is_a: GO:1904252 ! negative regulation of bile acid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006699 ! bile acid biosynthetic process
relationship: negatively_regulates GO:0006699 ! bile acid biosynthetic process
created_by: mah
creation_date: 2009-08-14T03:16:40Z

[Term]
id: GO:0070859
name: positive regulation of bile acid biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah]
synonym: "activation of bile acid biosynthetic process" NARROW [GOC:mah]
synonym: "positive regulation of bile acid anabolism" EXACT [GOC:mah]
synonym: "positive regulation of bile acid biosynthesis" EXACT [GOC:mah]
synonym: "positive regulation of bile acid formation" EXACT [GOC:mah]
synonym: "positive regulation of bile acid synthesis" EXACT [GOC:mah]
synonym: "stimulation of bile acid biosynthetic process" NARROW [GOC:mah]
synonym: "up regulation of bile acid biosynthetic process" EXACT [GOC:mah]
synonym: "up-regulation of bile acid biosynthetic process" EXACT [GOC:mah]
synonym: "upregulation of bile acid biosynthetic process" EXACT [GOC:mah]
is_a: GO:0010893 ! positive regulation of steroid biosynthetic process
is_a: GO:0031328 ! positive regulation of cellular biosynthetic process
is_a: GO:0070857 ! regulation of bile acid biosynthetic process
is_a: GO:1904253 ! positive regulation of bile acid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006699 ! bile acid biosynthetic process
relationship: positively_regulates GO:0006699 ! bile acid biosynthetic process
created_by: mah
creation_date: 2009-08-14T03:22:58Z

[Term]
id: GO:0070873
name: regulation of glycogen metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah]
synonym: "regulation of glycogen metabolism" EXACT [GOC:mah]
is_a: GO:0032881 ! regulation of polysaccharide metabolic process
is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0005977 ! glycogen metabolic process
relationship: regulates GO:0005977 ! glycogen metabolic process
created_by: mah
creation_date: 2009-08-20T02:44:53Z

[Term]
id: GO:0070874
name: negative regulation of glycogen metabolic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah]
synonym: "negative regulation of glycogen metabolism" EXACT [GOC:mah]
is_a: GO:0010605 ! negative regulation of macromolecule metabolic process
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process
is_a: GO:0070873 ! regulation of glycogen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0005977 ! glycogen metabolic process
relationship: negatively_regulates GO:0005977 ! glycogen metabolic process
created_by: mah
creation_date: 2009-08-20T02:50:41Z

[Term]
id: GO:0070875
name: positive regulation of glycogen metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah]
synonym: "positive regulation of glycogen metabolism" EXACT [GOC:mah]
is_a: GO:0010604 ! positive regulation of macromolecule metabolic process
is_a: GO:0010907 ! positive regulation of glucose metabolic process
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0070873 ! regulation of glycogen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0005977 ! glycogen metabolic process
relationship: positively_regulates GO:0005977 ! glycogen metabolic process
created_by: mah
creation_date: 2009-08-20T02:53:55Z

[Term]
id: GO:0070925
name: organelle assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah]
subset: goslim_yeast
is_a: GO:0006996 ! organelle organization
is_a: GO:0022607 ! cellular component assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0043226 ! organelle
relationship: results_in_assembly_of GO:0043226 ! organelle
created_by: mah
creation_date: 2009-09-15T03:00:51Z

[Term]
id: GO:0070977
name: bone maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state." [GOC:dph, GOC:mah]
is_a: GO:0048799 ! animal organ maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0001474 ! bone element
relationship: part_of GO:0060348 ! bone development
relationship: results_in_maturation_of UBERON:0001474 ! bone element
created_by: mah
creation_date: 2009-10-05T04:35:31Z

[Term]
id: GO:0071168
name: protein localization to chromatin
namespace: biological_process
def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin." [GOC:mah]
synonym: "protein localisation to chromatin" EXACT [GOC:mah]
is_a: GO:0034502 ! protein localization to chromosome
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0000785 ! chromatin
relationship: has_target_end_location GO:0000785 ! chromatin
created_by: mah
creation_date: 2009-11-20T11:51:20Z

[Term]
id: GO:0071169
name: establishment of protein localization to chromatin
namespace: biological_process
def: "The directed movement of a protein to a part of a chromosome that is organized into chromatin." [GOC:mah]
synonym: "establishment of protein localisation to chromatin" EXACT [GOC:mah]
is_a: GO:0070199 ! establishment of protein localization to chromosome
intersection_of: GO:0045184 ! establishment of protein localization
intersection_of: has_target_end_location GO:0000785 ! chromatin
relationship: has_target_end_location GO:0000785 ! chromatin
created_by: mah
creation_date: 2009-11-20T11:52:43Z

[Term]
id: GO:0071425
name: hematopoietic stem cell proliferation
namespace: biological_process
def: "The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop." [CL:0000037, GOC:add, GOC:BHF, GOC:mah, GOC:rl]
synonym: "hemopoietic stem cell proliferation" EXACT []
is_a: GO:0072089 ! stem cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000037 ! hematopoietic stem cell
relationship: acts_on_population_of CL:0000037 ! hematopoietic stem cell
relationship: part_of GO:0030097 ! hemopoiesis
created_by: mah
creation_date: 2009-12-16T10:22:52Z

[Term]
id: GO:0071626
name: mastication
namespace: biological_process
def: "The process of biting and mashing food with the teeth prior to swallowing." [GOC:gvg]
synonym: "chewing" EXACT [GOC:mah]
is_a: GO:0022600 ! digestive system process
created_by: mah
creation_date: 2010-02-10T11:19:48Z

[Term]
id: GO:0071674
name: mononuclear cell migration
namespace: biological_process
def: "The movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah]
is_a: GO:0050900 ! leukocyte migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000842 ! mononuclear cell
relationship: results_in_movement_of CL:0000842 ! mononuclear cell
created_by: mah
creation_date: 2010-02-16T02:11:00Z

[Term]
id: GO:0071675
name: regulation of mononuclear cell migration
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah]
is_a: GO:0002685 ! regulation of leukocyte migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0071674 ! mononuclear cell migration
relationship: regulates GO:0071674 ! mononuclear cell migration
created_by: mah
creation_date: 2010-02-16T02:11:53Z

[Term]
id: GO:0071676
name: negative regulation of mononuclear cell migration
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah]
synonym: "down regulation of mononuclear cell migration" EXACT [GOC:mah]
synonym: "down-regulation of mononuclear cell migration" EXACT [GOC:mah]
synonym: "downregulation of mononuclear cell migration" EXACT [GOC:mah]
synonym: "inhibition of mononuclear cell migration" NARROW [GOC:mah]
is_a: GO:0002686 ! negative regulation of leukocyte migration
is_a: GO:0071675 ! regulation of mononuclear cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0071674 ! mononuclear cell migration
relationship: negatively_regulates GO:0071674 ! mononuclear cell migration
created_by: mah
creation_date: 2010-02-16T02:13:55Z

[Term]
id: GO:0071677
name: positive regulation of mononuclear cell migration
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah]
synonym: "activation of mononuclear cell migration" NARROW [GOC:mah]
synonym: "stimulation of mononuclear cell migration" NARROW [GOC:mah]
synonym: "up regulation of mononuclear cell migration" EXACT [GOC:mah]
synonym: "up-regulation of mononuclear cell migration" EXACT [GOC:mah]
synonym: "upregulation of mononuclear cell migration" EXACT [GOC:mah]
is_a: GO:0002687 ! positive regulation of leukocyte migration
is_a: GO:0071675 ! regulation of mononuclear cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0071674 ! mononuclear cell migration
relationship: positively_regulates GO:0071674 ! mononuclear cell migration
created_by: mah
creation_date: 2010-02-16T02:15:29Z

[Term]
id: GO:0071692
name: protein localization to extracellular region
namespace: biological_process
def: "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location." [GOC:mah]
synonym: "protein localisation in extracellular region" EXACT [GOC:mah]
synonym: "protein localization in extracellular region" EXACT []
is_a: GO:0008104 ! protein localization
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005576 ! extracellular region
relationship: has_target_end_location GO:0005576 ! extracellular region
created_by: mah
creation_date: 2010-02-25T04:00:13Z

[Term]
id: GO:0071695
name: anatomical structure maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state." [GOC:mah]
is_a: GO:0021700 ! developmental maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0000061 ! anatomical structure
relationship: part_of GO:0048856 ! anatomical structure development
relationship: results_in_maturation_of UBERON:0000061 ! anatomical structure
created_by: mah
creation_date: 2010-03-02T11:43:38Z

[Term]
id: GO:0071696
name: ectodermal placode development
namespace: biological_process
def: "The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005085 ! ectodermal placode
relationship: results_in_development_of UBERON:0005085 ! ectodermal placode
created_by: mah
creation_date: 2010-03-02T11:48:01Z

[Term]
id: GO:0071697
name: ectodermal placode morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005085 ! ectodermal placode
relationship: part_of GO:0071696 ! ectodermal placode development
relationship: results_in_morphogenesis_of UBERON:0005085 ! ectodermal placode
created_by: mah
creation_date: 2010-03-02T11:49:51Z

[Term]
id: GO:0071702
name: organic substance transport
namespace: biological_process
def: "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon." [GOC:mah]
is_a: GO:0006810 ! transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:50860 ! organic molecular entity
relationship: has_primary_input CHEBI:50860 ! organic molecular entity
created_by: mah
creation_date: 2010-03-08T02:15:14Z

[Term]
id: GO:0071704
name: organic substance metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah]
subset: gocheck_do_not_annotate
synonym: "organic molecular entity metabolic process" EXACT []
synonym: "organic molecular entity metabolism" EXACT []
synonym: "organic substance metabolism" EXACT []
is_a: GO:0008152 ! metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:50860 ! organic molecular entity
relationship: has_primary_input_or_output CHEBI:50860 ! organic molecular entity
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI
created_by: mah
creation_date: 2010-03-08T03:32:18Z

[Term]
id: GO:0071705
name: nitrogen compound transport
namespace: biological_process
def: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
is_a: GO:0006810 ! transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:51143 ! nitrogen molecular entity
relationship: has_primary_input CHEBI:51143 ! nitrogen molecular entity
created_by: mah
creation_date: 2010-03-08T03:56:28Z

[Term]
id: GO:0071709
name: membrane assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form a membrane." [GOC:mah]
is_a: GO:0022607 ! cellular component assembly
is_a: GO:0061024 ! membrane organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0016020 ! membrane
relationship: part_of GO:0044091 ! membrane biogenesis
relationship: results_in_assembly_of GO:0016020 ! membrane
created_by: mah
creation_date: 2010-03-10T11:19:17Z

[Term]
id: GO:0071711
name: basement membrane organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane." [GOC:mah]
comment: Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer.
synonym: "basement membrane organisation" EXACT [GOC:mah]
is_a: GO:0030198 ! extracellular matrix organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005604 ! basement membrane
relationship: results_in_organization_of GO:0005604 ! basement membrane
created_by: mah
creation_date: 2010-03-10T11:57:10Z

[Term]
id: GO:0071763
name: nuclear membrane organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane." [GOC:mah]
synonym: "nuclear membrane organisation" EXACT [GOC:mah]
synonym: "nuclear membrane organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0061024 ! membrane organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0031965 ! nuclear membrane
relationship: part_of GO:0006998 ! nuclear envelope organization
relationship: results_in_organization_of GO:0031965 ! nuclear membrane
created_by: mah
creation_date: 2010-03-29T03:59:35Z

[Term]
id: GO:0071764
name: nuclear outer membrane organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane." [GOC:mah]
synonym: "nuclear outer membrane organisation" EXACT [GOC:mah]
synonym: "nuclear outer membrane organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0071763 ! nuclear membrane organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0005640 ! nuclear outer membrane
relationship: results_in_organization_of GO:0005640 ! nuclear outer membrane
created_by: mah
creation_date: 2010-03-29T04:03:37Z

[Term]
id: GO:0071806
name: protein transmembrane transport
namespace: biological_process
def: "The process in which a protein is transported across a membrane." [GOC:mah, GOC:vw]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "protein membrane transport" EXACT []
is_a: GO:0045184 ! establishment of protein localization
is_a: GO:0055085 ! transmembrane transport
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:36080 ! protein
intersection_of: results_in_transport_across GO:0016020 ! membrane
created_by: mah
creation_date: 2010-09-03T02:54:26Z

[Term]
id: GO:0071824
name: protein-DNA complex organization
namespace: biological_process
def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex." [GOC:mah]
synonym: "DNA-protein complex subunit organization" EXACT [GOC:mah]
synonym: "protein-DNA complex subunit organisation" EXACT [GOC:mah]
synonym: "protein-DNA complex subunit organization" EXACT []
is_a: GO:0043933 ! protein-containing complex organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0032993 ! protein-DNA complex
relationship: results_in_organization_of GO:0032993 ! protein-DNA complex
created_by: mah
creation_date: 2010-09-08T10:03:26Z

[Term]
id: GO:0071826
name: protein-RNA complex organization
namespace: biological_process
def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex." [GOC:mah]
synonym: "protein-RNA complex subunit organization" EXACT [GOC:mah]
synonym: "ribonucleoprotein complex subunit organisation" EXACT [GOC:mah]
synonym: "ribonucleoprotein complex subunit organization" EXACT []
synonym: "RNA-protein complex subunit organization" EXACT [GOC:mah]
is_a: GO:0043933 ! protein-containing complex organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:1990904 ! ribonucleoprotein complex
relationship: results_in_organization_of GO:1990904 ! ribonucleoprotein complex
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25143" xsd:anyURI
created_by: mah
creation_date: 2010-09-08T10:10:35Z

[Term]
id: GO:0071840
name: cellular component organization or biogenesis
namespace: biological_process
alt_id: GO:0071841
def: "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:mah]
subset: goslim_flybase_ribbon
subset: goslim_metagenomics
synonym: "cellular component organisation or biogenesis" EXACT [GOC:mah]
synonym: "cellular component organisation or biogenesis at cellular level" EXACT [GOC:mah]
synonym: "cellular component organization or biogenesis at cellular level" EXACT []
is_a: GO:0009987 ! cellular process
created_by: mah
creation_date: 2010-09-10T01:39:16Z

[Term]
id: GO:0071867
name: response to monoamine
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [GOC:mah]
synonym: "response to monoamine stimulus" EXACT [GOC:dos]
is_a: GO:0010243 ! response to organonitrogen compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:63534 ! monoamine
relationship: has_primary_input CHEBI:63534 ! monoamine
created_by: mah
creation_date: 2010-09-13T02:36:37Z

[Term]
id: GO:0071869
name: response to catecholamine
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [GOC:BHF, GOC:mah]
synonym: "response to catecholamine stimulus" EXACT [GOC:dos]
is_a: GO:0014070 ! response to organic cyclic compound
is_a: GO:0071867 ! response to monoamine
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:33567 ! catecholamine
relationship: has_primary_input CHEBI:33567 ! catecholamine
created_by: mah
creation_date: 2010-09-13T02:51:13Z

[Term]
id: GO:0071873
name: response to norepinephrine
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." [GOC:BHF, GOC:mah]
comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.
synonym: "response to noradrenaline stimulus" EXACT [GOC:mah]
synonym: "response to norepinephrine stimulus" EXACT [GOC:dos]
is_a: GO:0010033 ! response to organic substance
is_a: GO:1901698 ! response to nitrogen compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+)
relationship: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+)
created_by: mah
creation_date: 2010-09-13T03:31:53Z

[Term]
id: GO:0071887
name: leukocyte apoptotic process
namespace: biological_process
def: "Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:BHF, GOC:mah, GOC:mtg_apoptosis]
comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).
synonym: "leukocyte apoptosis" NARROW []
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000738 ! leukocyte
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: occurs_in CL:0000738 ! leukocyte
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
created_by: mah
creation_date: 2010-09-14T12:44:09Z

[Term]
id: GO:0071897
name: DNA biosynthetic process
namespace: biological_process
def: "The biosynthetic process resulting in the formation of DNA." [GOC:mah]
synonym: "DNA anabolism" EXACT [GOC:mah]
synonym: "DNA biosynthesis" EXACT [GOC:mah]
synonym: "DNA formation" EXACT [GOC:mah]
synonym: "DNA synthesis" EXACT [GOC:mah]
is_a: GO:0006259 ! DNA metabolic process
is_a: GO:0009059 ! macromolecule biosynthetic process
is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:16991 ! deoxyribonucleic acid
relationship: has_primary_output CHEBI:16991 ! deoxyribonucleic acid
created_by: mah
creation_date: 2010-09-15T02:14:33Z

[Term]
id: GO:0071944
name: cell periphery
namespace: cellular_component
def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt]
subset: goslim_flybase_ribbon
is_a: GO:0110165 ! cellular anatomical entity
created_by: mah
creation_date: 2010-10-04T01:51:47Z

[Term]
id: GO:0071953
name: elastic fiber
namespace: cellular_component
def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, GOC:mah, PMID:20236620]
synonym: "elastic fibre" EXACT [GOC:mah]
synonym: "elastin fiber" EXACT [GOC:BHF]
is_a: GO:0099512 ! supramolecular fiber
relationship: part_of GO:0031012 ! extracellular matrix
created_by: mah
creation_date: 2010-10-11T11:44:57Z

[Term]
id: GO:0071971
name: extracellular exosome assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm." [GOC:mah, GOC:tfm, PMID:19442504, PMID:27462458]
synonym: "extracellular vesicular exosome assembly" EXACT [GOC:vesicles]
is_a: GO:0016050 ! vesicle organization
is_a: GO:0070925 ! organelle assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0070062 ! extracellular exosome
relationship: part_of GO:0097734 ! extracellular exosome biogenesis
relationship: results_in_assembly_of GO:0070062 ! extracellular exosome
created_by: mah
creation_date: 2010-10-18T03:44:18Z

[Term]
id: GO:0072001
name: renal system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels." [GOC:mtg_kidney_jan10, GOC:yaf, http://en.wikibooks.org/wiki/Human_Physiology/The_Urinary_System]
subset: gocheck_do_not_annotate
synonym: "urinary system development" BROAD [GOC:yaf]
synonym: "urinary tract development" BROAD [GOC:yaf, PMID:17881463]
is_a: GO:0048731 ! system development
intersection_of: GO:0048731 ! system development
intersection_of: results_in_development_of UBERON:0001008 ! renal system
relationship: results_in_development_of UBERON:0001008 ! renal system
created_by: mah
creation_date: 2010-01-25T10:31:00Z

[Term]
id: GO:0072003
name: kidney rudiment formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10]
synonym: "kidney anlage formation" RELATED [GOC:mtg_kidney_jan10]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005095 ! kidney rudiment
relationship: part_of GO:0060993 ! kidney morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0005095 ! kidney rudiment
created_by: mah
creation_date: 2010-01-25T11:18:58Z

[Term]
id: GO:0072006
name: nephron development
namespace: biological_process
def: "The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10]
synonym: "nephrogenesis" RELATED [GOC:rph]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001285 ! nephron
relationship: part_of GO:0001822 ! kidney development
relationship: results_in_development_of UBERON:0001285 ! nephron
created_by: mah
creation_date: 2010-01-25T01:37:16Z

[Term]
id: GO:0072009
name: nephron epithelium development
namespace: biological_process
def: "The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10]
is_a: GO:0072073 ! kidney epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004211 ! nephron epithelium
relationship: part_of GO:0072006 ! nephron development
relationship: results_in_development_of UBERON:0004211 ! nephron epithelium
created_by: mah
creation_date: 2010-01-25T02:01:39Z

[Term]
id: GO:0072028
name: nephron morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001285 ! nephron
relationship: part_of GO:0060993 ! kidney morphogenesis
relationship: part_of GO:0072006 ! nephron development
relationship: results_in_morphogenesis_of UBERON:0001285 ! nephron
created_by: mah
creation_date: 2010-01-25T02:45:52Z

[Term]
id: GO:0072033
name: renal vesicle formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10]
synonym: "nephron epithelium formation" RELATED [GOC:mtg_kidney_jan10]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0004209 ! renal vesicle
relationship: part_of GO:0072077 ! renal vesicle morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0004209 ! renal vesicle
created_by: mah
creation_date: 2010-01-25T02:57:03Z

[Term]
id: GO:0072036
name: mesenchymal to epithelial transition involved in renal vesicle formation
namespace: biological_process
def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle." [GOC:mtg_kidney_jan10]
is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development
is_a: GO:0060231 ! mesenchymal to epithelial transition
intersection_of: GO:0060231 ! mesenchymal to epithelial transition
intersection_of: part_of GO:0072033 ! renal vesicle formation
relationship: part_of GO:0072033 ! renal vesicle formation
created_by: mah
creation_date: 2010-01-25T03:04:24Z

[Term]
id: GO:0072038
name: mesenchymal stem cell maintenance involved in nephron morphogenesis
namespace: biological_process
def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10]
is_a: GO:0035019 ! somatic stem cell population maintenance
relationship: part_of GO:0072028 ! nephron morphogenesis
created_by: mah
creation_date: 2010-01-25T03:08:05Z

[Term]
id: GO:0072039
name: regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
namespace: biological_process
def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW []
synonym: "regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT []
is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis
is_a: GO:1904672 ! regulation of somatic stem cell population maintenance
is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis
relationship: regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis
relationship: regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis
created_by: mah
creation_date: 2010-01-25T03:08:34Z

[Term]
id: GO:0072040
name: negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
namespace: biological_process
def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW []
synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT []
is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis
is_a: GO:1904673 ! negative regulation of somatic stem cell population maintenance
is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis
relationship: negatively_regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis
relationship: negatively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis
created_by: mah
creation_date: 2010-01-25T03:09:30Z

[Term]
id: GO:0072041
name: positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
namespace: biological_process
def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW []
synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT []
is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis
is_a: GO:1904674 ! positive regulation of somatic stem cell population maintenance
is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis
relationship: positively_regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis
relationship: positively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis
created_by: mah
creation_date: 2010-01-25T03:10:32Z

[Term]
id: GO:0072044
name: collecting duct development
namespace: biological_process
def: "The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10]
is_a: GO:0035295 ! tube development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001232 ! collecting duct of renal tubule
relationship: part_of GO:0001822 ! kidney development
relationship: results_in_development_of UBERON:0001232 ! collecting duct of renal tubule
created_by: mah
creation_date: 2010-01-25T03:18:06Z

[Term]
id: GO:0072048
name: renal system pattern specification
namespace: biological_process
def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system." [GOC:mtg_kidney_jan10]
subset: gocheck_do_not_annotate
synonym: "renal system pattern formation" RELATED [GOC:mtg_kidney_jan10]
is_a: GO:0007389 ! pattern specification process
relationship: part_of GO:0072001 ! renal system development
created_by: mah
creation_date: 2010-01-25T03:31:51Z

[Term]
id: GO:0072055
name: renal cortex development
namespace: biological_process
def: "The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001225 ! cortex of kidney
relationship: part_of GO:0001822 ! kidney development
relationship: results_in_development_of UBERON:0001225 ! cortex of kidney
created_by: mah
creation_date: 2010-01-25T04:01:12Z

[Term]
id: GO:0072059
name: cortical collecting duct development
namespace: biological_process
def: "The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004203 ! cortical collecting duct
relationship: results_in_development_of UBERON:0004203 ! cortical collecting duct
created_by: mah
creation_date: 2010-01-25T04:07:07Z

[Term]
id: GO:0072071
name: kidney interstitial fibroblast differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]
synonym: "kidney interstitial cell differentiation" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0061005 ! cell differentiation involved in kidney development
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000692 ! kidney interstitial fibroblast
relationship: results_in_acquisition_of_features_of CL:1000692 ! kidney interstitial fibroblast
created_by: mah
creation_date: 2010-01-25T04:34:31Z

[Term]
id: GO:0072073
name: kidney epithelium development
namespace: biological_process
def: "The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10]
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004819 ! kidney epithelium
relationship: part_of GO:0001822 ! kidney development
relationship: results_in_development_of UBERON:0004819 ! kidney epithelium
created_by: mah
creation_date: 2010-01-25T04:37:42Z

[Term]
id: GO:0072074
name: kidney mesenchyme development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0060485 ! mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003918 ! kidney mesenchyme
relationship: part_of GO:0001822 ! kidney development
relationship: results_in_development_of UBERON:0003918 ! kidney mesenchyme
created_by: mah
creation_date: 2010-01-25T04:39:04Z

[Term]
id: GO:0072075
name: metanephric mesenchyme development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072074 ! kidney mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003220 ! metanephric mesenchyme
relationship: part_of GO:0001656 ! metanephros development
relationship: results_in_development_of UBERON:0003220 ! metanephric mesenchyme
created_by: mah
creation_date: 2010-01-25T04:40:11Z

[Term]
id: GO:0072076
name: nephrogenic mesenchyme development
namespace: biological_process
def: "The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10]
is_a: GO:0072074 ! kidney mesenchyme development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004208 ! nephrogenic mesenchyme
relationship: part_of GO:0072006 ! nephron development
relationship: results_in_development_of UBERON:0004208 ! nephrogenic mesenchyme
created_by: mah
creation_date: 2010-01-25T04:40:44Z

[Term]
id: GO:0072077
name: renal vesicle morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10]
is_a: GO:0002009 ! morphogenesis of an epithelium
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004209 ! renal vesicle
relationship: part_of GO:0072087 ! renal vesicle development
relationship: part_of GO:0072088 ! nephron epithelium morphogenesis
relationship: results_in_morphogenesis_of UBERON:0004209 ! renal vesicle
created_by: mah
creation_date: 2010-02-01T02:21:06Z

[Term]
id: GO:0072078
name: nephron tubule morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0061333 ! renal tubule morphogenesis
is_a: GO:0072088 ! nephron epithelium morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001231 ! nephron tubule
relationship: part_of GO:0072080 ! nephron tubule development
relationship: results_in_morphogenesis_of UBERON:0001231 ! nephron tubule
created_by: mah
creation_date: 2010-02-01T02:25:14Z

[Term]
id: GO:0072079
name: nephron tubule formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0001838 ! embryonic epithelial tube formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0001231 ! nephron tubule
relationship: part_of GO:0072078 ! nephron tubule morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0001231 ! nephron tubule
created_by: mah
creation_date: 2010-02-01T02:29:26Z

[Term]
id: GO:0072080
name: nephron tubule development
namespace: biological_process
def: "The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0061326 ! renal tubule development
is_a: GO:0072009 ! nephron epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001231 ! nephron tubule
relationship: results_in_development_of UBERON:0001231 ! nephron tubule
created_by: mah
creation_date: 2010-02-01T02:32:12Z

[Term]
id: GO:0072087
name: renal vesicle development
namespace: biological_process
def: "The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10]
is_a: GO:0072073 ! kidney epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004209 ! renal vesicle
relationship: part_of GO:0072009 ! nephron epithelium development
relationship: results_in_development_of UBERON:0004209 ! renal vesicle
created_by: mah
creation_date: 2010-02-08T01:18:31Z

[Term]
id: GO:0072088
name: nephron epithelium morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10]
is_a: GO:0002009 ! morphogenesis of an epithelium
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004211 ! nephron epithelium
relationship: part_of GO:0072009 ! nephron epithelium development
relationship: part_of GO:0072028 ! nephron morphogenesis
relationship: results_in_morphogenesis_of UBERON:0004211 ! nephron epithelium
created_by: mah
creation_date: 2010-02-08T01:19:06Z

[Term]
id: GO:0072089
name: stem cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000034 ! stem cell
relationship: acts_on_population_of CL:0000034 ! stem cell
relationship: has_part GO:0017145 ! stem cell division
created_by: mah
creation_date: 2010-02-08T02:03:36Z

[Term]
id: GO:0072091
name: regulation of stem cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072089 ! stem cell proliferation
relationship: regulates GO:0072089 ! stem cell proliferation
created_by: mah
creation_date: 2010-02-08T02:09:03Z

[Term]
id: GO:0072093
name: metanephric renal vesicle formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the metanephros." [GOC:mtg_kidney_jan10]
synonym: "metanephros formation" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0072033 ! renal vesicle formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005147 ! metanephric renal vesicle
relationship: part_of GO:0072283 ! metanephric renal vesicle morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0005147 ! metanephric renal vesicle
created_by: mah
creation_date: 2010-02-10T01:17:11Z

[Term]
id: GO:0072098
name: anterior/posterior pattern specification involved in kidney development
namespace: biological_process
def: "The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10]
synonym: "anterior/posterior pattern formation involved in kidney development" RELATED [GOC:mtg_kidney_jan10]
synonym: "kidney anterior/posterior pattern formation" RELATED [GOC:mtg_kidney_jan10]
synonym: "kidney anterior/posterior pattern specification" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0009952 ! anterior/posterior pattern specification
is_a: GO:0061004 ! pattern specification involved in kidney development
intersection_of: GO:0009952 ! anterior/posterior pattern specification
intersection_of: part_of GO:0001822 ! kidney development
created_by: mah
creation_date: 2010-02-10T02:06:24Z

[Term]
id: GO:0072099
name: anterior/posterior pattern specification involved in ureteric bud development
namespace: biological_process
def: "The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10]
synonym: "ureteric bud anterior/posterior pattern formation" RELATED [GOC:mtg_kidney_jan10]
is_a: GO:0061227 ! pattern specification involved in mesonephros development
is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development
intersection_of: GO:0009952 ! anterior/posterior pattern specification
intersection_of: part_of GO:0001657 ! ureteric bud development
relationship: part_of GO:0001657 ! ureteric bud development
created_by: mah
creation_date: 2010-02-10T02:12:09Z

[Term]
id: GO:0072105
name: ureteric peristalsis
namespace: biological_process
def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_kidney_jan10]
is_a: GO:0014849 ! ureter smooth muscle contraction
is_a: GO:0030432 ! peristalsis
intersection_of: GO:0030432 ! peristalsis
intersection_of: occurs_in UBERON:0000056 ! ureter
relationship: occurs_in UBERON:0000056 ! ureter
created_by: mah
creation_date: 2010-02-10T03:07:54Z

[Term]
id: GO:0072106
name: regulation of ureteric bud formation
namespace: biological_process
def: "Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10]
is_a: GO:0061217 ! regulation of mesonephros development
is_a: GO:1905276 ! regulation of epithelial tube formation
is_a: GO:2000027 ! regulation of animal organ morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060676 ! ureteric bud formation
relationship: regulates GO:0060676 ! ureteric bud formation
created_by: mah
creation_date: 2010-02-12T02:34:40Z

[Term]
id: GO:0072107
name: positive regulation of ureteric bud formation
namespace: biological_process
def: "Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10]
is_a: GO:0072106 ! regulation of ureteric bud formation
is_a: GO:0110110 ! positive regulation of animal organ morphogenesis
is_a: GO:1905278 ! positive regulation of epithelial tube formation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060676 ! ureteric bud formation
relationship: positively_regulates GO:0060676 ! ureteric bud formation
created_by: mah
creation_date: 2010-02-12T02:37:28Z

[Term]
id: GO:0072108
name: positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium
is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis
relationship: positively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis
created_by: mah
creation_date: 2010-02-12T02:45:57Z

[Term]
id: GO:0072111
name: cell proliferation involved in kidney development
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: part_of GO:0001822 ! kidney development
relationship: part_of GO:0001822 ! kidney development
created_by: mah
creation_date: 2010-02-22T10:48:45Z

[Term]
id: GO:0072114
name: pronephros morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10]
synonym: "pronephric kidney morphogenesis" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0060993 ! kidney morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002120 ! pronephros
relationship: part_of GO:0048793 ! pronephros development
relationship: results_in_morphogenesis_of UBERON:0002120 ! pronephros
created_by: mah
creation_date: 2010-02-22T11:12:15Z

[Term]
id: GO:0072116
name: pronephros formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10]
synonym: "pronephric kidney formation" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0048645 ! animal organ formation
is_a: GO:0072003 ! kidney rudiment formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002120 ! pronephros
relationship: part_of GO:0072114 ! pronephros morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002120 ! pronephros
created_by: mah
creation_date: 2010-02-22T11:16:26Z

[Term]
id: GO:0072120
name: pronephros maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10]
synonym: "pronephric kidney maturation" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0048799 ! animal organ maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of UBERON:0002120 ! pronephros
relationship: part_of GO:0048793 ! pronephros development
relationship: results_in_maturation_of UBERON:0002120 ! pronephros
created_by: mah
creation_date: 2010-02-22T11:25:48Z

[Term]
id: GO:0072127
name: renal capsule development
namespace: biological_process
def: "The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10]
is_a: GO:0061448 ! connective tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002015 ! kidney capsule
relationship: part_of GO:0001822 ! kidney development
relationship: results_in_development_of UBERON:0002015 ! kidney capsule
created_by: mah
creation_date: 2010-02-22T02:02:55Z

[Term]
id: GO:0072128
name: renal capsule morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10]
is_a: GO:0048729 ! tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002015 ! kidney capsule
relationship: part_of GO:0072127 ! renal capsule development
relationship: results_in_morphogenesis_of UBERON:0002015 ! kidney capsule
created_by: mah
creation_date: 2010-02-22T02:06:19Z

[Term]
id: GO:0072129
name: renal capsule formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0002015 ! kidney capsule
relationship: part_of GO:0072128 ! renal capsule morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0002015 ! kidney capsule
created_by: mah
creation_date: 2010-02-22T02:08:14Z

[Term]
id: GO:0072131
name: kidney mesenchyme morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0072132 ! mesenchyme morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003918 ! kidney mesenchyme
relationship: part_of GO:0072074 ! kidney mesenchyme development
relationship: results_in_morphogenesis_of UBERON:0003918 ! kidney mesenchyme
created_by: mah
creation_date: 2010-02-22T02:16:43Z

[Term]
id: GO:0072132
name: mesenchyme morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:mtg_kidney_jan10]
is_a: GO:0048729 ! tissue morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003104 ! mesenchyme
relationship: part_of GO:0009887 ! animal organ morphogenesis
relationship: part_of GO:0060485 ! mesenchyme development
relationship: results_in_morphogenesis_of UBERON:0003104 ! mesenchyme
created_by: mah
creation_date: 2010-02-22T02:17:15Z

[Term]
id: GO:0072133
name: metanephric mesenchyme morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072131 ! kidney mesenchyme morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003220 ! metanephric mesenchyme
relationship: part_of GO:0072075 ! metanephric mesenchyme development
relationship: results_in_morphogenesis_of UBERON:0003220 ! metanephric mesenchyme
created_by: mah
creation_date: 2010-02-22T02:20:14Z

[Term]
id: GO:0072134
name: nephrogenic mesenchyme morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10]
is_a: GO:0072131 ! kidney mesenchyme morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0004208 ! nephrogenic mesenchyme
relationship: part_of GO:0072076 ! nephrogenic mesenchyme development
relationship: results_in_morphogenesis_of UBERON:0004208 ! nephrogenic mesenchyme
created_by: mah
creation_date: 2010-02-22T02:21:16Z

[Term]
id: GO:0072138
name: mesenchymal cell proliferation involved in ureteric bud development
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development." [GOC:mtg_kidney_jan10]
synonym: "ureteric bud mesenchymal cell proliferation" BROAD [GOC:mtg_kidney_jan10]
is_a: GO:0010463 ! mesenchymal cell proliferation
is_a: GO:0061209 ! cell proliferation involved in mesonephros development
intersection_of: GO:0010463 ! mesenchymal cell proliferation
intersection_of: part_of GO:0001657 ! ureteric bud development
relationship: part_of GO:0001657 ! ureteric bud development
created_by: mah
creation_date: 2010-02-22T02:40:38Z

[Term]
id: GO:0072141
name: renal interstitial fibroblast development
namespace: biological_process
def: "The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10]
synonym: "kidney interstitial cell development" EXACT [GOC:mtg_kidney_jan10]
is_a: GO:0048468 ! cell development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of CL:1000692 ! kidney interstitial fibroblast
relationship: part_of GO:0072071 ! kidney interstitial fibroblast differentiation
relationship: results_in_development_of CL:1000692 ! kidney interstitial fibroblast
created_by: mah
creation_date: 2010-02-24T01:39:05Z

[Term]
id: GO:0072155
name: epithelial cell migration involved in nephron tubule morphogenesis
namespace: biological_process
def: "The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis." [GOC:mtg_kidney_jan10]
is_a: GO:0010631 ! epithelial cell migration
is_a: GO:0035787 ! cell migration involved in kidney development
intersection_of: GO:0010631 ! epithelial cell migration
intersection_of: part_of GO:0072078 ! nephron tubule morphogenesis
relationship: part_of GO:0072078 ! nephron tubule morphogenesis
created_by: mah
creation_date: 2010-02-24T02:21:25Z

[Term]
id: GO:0072160
name: nephron tubule epithelial cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]
is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000494 ! nephron tubule epithelial cell
relationship: part_of GO:0072080 ! nephron tubule development
relationship: results_in_acquisition_of_features_of CL:1000494 ! nephron tubule epithelial cell
created_by: mah
creation_date: 2010-02-24T02:40:11Z

[Term]
id: GO:0072161
name: mesenchymal cell differentiation involved in kidney development
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]
is_a: GO:0061005 ! cell differentiation involved in kidney development
is_a: GO:2001012 ! mesenchymal cell differentiation involved in renal system development
intersection_of: GO:0048762 ! mesenchymal cell differentiation
intersection_of: part_of GO:0001822 ! kidney development
relationship: part_of GO:0072074 ! kidney mesenchyme development
created_by: mah
creation_date: 2010-02-26T01:31:49Z

[Term]
id: GO:0072163
name: mesonephric epithelium development
namespace: biological_process
def: "The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10]
is_a: GO:0072073 ! kidney epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005103 ! mesonephric epithelium
relationship: part_of GO:0001823 ! mesonephros development
relationship: results_in_development_of UBERON:0005103 ! mesonephric epithelium
created_by: mah
creation_date: 2010-02-26T01:40:43Z

[Term]
id: GO:0072164
name: mesonephric tubule development
namespace: biological_process
def: "The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10]
is_a: GO:0035295 ! tube development
is_a: GO:0072163 ! mesonephric epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000083 ! mesonephric tubule
relationship: results_in_development_of UBERON:0000083 ! mesonephric tubule
created_by: mah
creation_date: 2010-02-26T01:45:58Z

[Term]
id: GO:0072170
name: metanephric tubule development
namespace: biological_process
def: "The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0035295 ! tube development
is_a: GO:0072207 ! metanephric epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005106 ! metanephric tubule
relationship: results_in_development_of UBERON:0005106 ! metanephric tubule
created_by: mah
creation_date: 2010-02-26T01:58:18Z

[Term]
id: GO:0072171
name: mesonephric tubule morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072078 ! nephron tubule morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000083 ! mesonephric tubule
relationship: part_of GO:0072164 ! mesonephric tubule development
relationship: results_in_morphogenesis_of UBERON:0000083 ! mesonephric tubule
created_by: mah
creation_date: 2010-02-26T02:02:13Z

[Term]
id: GO:0072172
name: mesonephric tubule formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072079 ! nephron tubule formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0000083 ! mesonephric tubule
relationship: part_of GO:0072171 ! mesonephric tubule morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0000083 ! mesonephric tubule
created_by: mah
creation_date: 2010-02-26T02:02:37Z

[Term]
id: GO:0072173
name: metanephric tubule morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0060562 ! epithelial tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005106 ! metanephric tubule
relationship: part_of GO:0072170 ! metanephric tubule development
relationship: results_in_morphogenesis_of UBERON:0005106 ! metanephric tubule
created_by: mah
creation_date: 2010-02-26T02:06:42Z

[Term]
id: GO:0072174
name: metanephric tubule formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a metanephric tubule." [GOC:mtg_kidney_jan10]
is_a: GO:0072175 ! epithelial tube formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005106 ! metanephric tubule
relationship: part_of GO:0072173 ! metanephric tubule morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0005106 ! metanephric tubule
created_by: mah
creation_date: 2010-02-26T02:07:41Z

[Term]
id: GO:0072175
name: epithelial tube formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of an epithelial tube." [GOC:mtg_kidney_jan10]
is_a: GO:0035148 ! tube formation
intersection_of: GO:0035148 ! tube formation
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003914 ! epithelial tube
relationship: part_of GO:0060562 ! epithelial tube morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0003914 ! epithelial tube
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22302" xsd:anyURI
created_by: mah
creation_date: 2010-02-26T02:15:40Z

[Term]
id: GO:0072176
name: nephric duct development
namespace: biological_process
def: "The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0035295 ! tube development
is_a: GO:0072073 ! kidney epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0009201 ! nephric duct
relationship: results_in_development_of UBERON:0009201 ! nephric duct
created_by: mah
creation_date: 2010-02-26T02:27:31Z

[Term]
id: GO:0072177
name: mesonephric duct development
namespace: biological_process
def: "The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10]
synonym: "Wolffian duct development" EXACT [GOC:dph]
is_a: GO:0072164 ! mesonephric tubule development
is_a: GO:0072176 ! nephric duct development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003074 ! mesonephric duct
relationship: results_in_development_of UBERON:0003074 ! mesonephric duct
created_by: mah
creation_date: 2010-02-26T02:32:22Z

[Term]
id: GO:0072178
name: nephric duct morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0060562 ! epithelial tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0009201 ! nephric duct
relationship: part_of GO:0072176 ! nephric duct development
relationship: results_in_morphogenesis_of UBERON:0009201 ! nephric duct
created_by: mah
creation_date: 2010-02-26T02:35:29Z

[Term]
id: GO:0072179
name: nephric duct formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0072175 ! epithelial tube formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0009201 ! nephric duct
relationship: part_of GO:0072178 ! nephric duct morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0009201 ! nephric duct
created_by: mah
creation_date: 2010-02-26T02:35:55Z

[Term]
id: GO:0072180
name: mesonephric duct morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10]
synonym: "Wolffian duct morphogenesis" RELATED [GOC:dph]
is_a: GO:0072171 ! mesonephric tubule morphogenesis
is_a: GO:0072178 ! nephric duct morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0003074 ! mesonephric duct
relationship: part_of GO:0072177 ! mesonephric duct development
relationship: results_in_morphogenesis_of UBERON:0003074 ! mesonephric duct
created_by: mah
creation_date: 2010-02-26T02:37:13Z

[Term]
id: GO:0072181
name: mesonephric duct formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros." [GOC:mtg_kidney_jan10]
synonym: "Wolffian duct formation" EXACT [GOC:dph]
is_a: GO:0072172 ! mesonephric tubule formation
is_a: GO:0072179 ! nephric duct formation
is_a: GO:0072180 ! mesonephric duct morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003074 ! mesonephric duct
relationship: results_in_formation_of_anatomical_entity UBERON:0003074 ! mesonephric duct
created_by: mah
creation_date: 2010-02-26T02:38:03Z

[Term]
id: GO:0072182
name: regulation of nephron tubule epithelial cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10]
is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072160 ! nephron tubule epithelial cell differentiation
relationship: regulates GO:0072160 ! nephron tubule epithelial cell differentiation
created_by: mah
creation_date: 2010-02-26T02:45:09Z

[Term]
id: GO:0072183
name: negative regulation of nephron tubule epithelial cell differentiation
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10]
is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation
is_a: GO:0090185 ! negative regulation of kidney development
is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation
relationship: negatively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation
created_by: mah
creation_date: 2010-02-26T02:47:25Z

[Term]
id: GO:0072189
name: ureter development
namespace: biological_process
def: "The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:mtg_kidney_jan10]
is_a: GO:0035295 ! tube development
is_a: GO:0048513 ! animal organ development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000056 ! ureter
relationship: part_of GO:0072001 ! renal system development
relationship: results_in_development_of UBERON:0000056 ! ureter
created_by: mah
creation_date: 2010-03-01T01:44:14Z

[Term]
id: GO:0072191
name: ureter smooth muscle development
namespace: biological_process
def: "The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10]
is_a: GO:0048745 ! smooth muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0009919 ! ureter smooth muscle
relationship: part_of GO:0072189 ! ureter development
relationship: results_in_development_of UBERON:0009919 ! ureter smooth muscle
created_by: mah
creation_date: 2010-03-01T01:48:53Z

[Term]
id: GO:0072193
name: ureter smooth muscle cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter." [GOC:mtg_kidney_jan10]
is_a: GO:0051145 ! smooth muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000979 ! ureter smooth muscle cell
relationship: part_of GO:0072191 ! ureter smooth muscle development
relationship: results_in_acquisition_of_features_of CL:1000979 ! ureter smooth muscle cell
created_by: mah
creation_date: 2010-03-01T01:55:01Z

[Term]
id: GO:0072194
name: kidney smooth muscle tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10]
is_a: GO:0048745 ! smooth muscle tissue development
relationship: part_of GO:0001822 ! kidney development
created_by: mah
creation_date: 2010-03-01T02:05:30Z

[Term]
id: GO:0072197
name: ureter morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder." [GOC:mtg_kidney_jan10]
is_a: GO:0009887 ! animal organ morphogenesis
is_a: GO:0035239 ! tube morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000056 ! ureter
relationship: part_of GO:0072189 ! ureter development
relationship: results_in_morphogenesis_of UBERON:0000056 ! ureter
created_by: mah
creation_date: 2010-03-01T02:24:55Z

[Term]
id: GO:0072198
name: mesenchymal cell proliferation involved in ureter development
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development." [GOC:mtg_kidney_jan10]
synonym: "ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10]
synonym: "ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10]
is_a: GO:0010463 ! mesenchymal cell proliferation
intersection_of: GO:0010463 ! mesenchymal cell proliferation
intersection_of: part_of GO:0072189 ! ureter development
relationship: part_of GO:0072189 ! ureter development
created_by: mah
creation_date: 2010-03-01T03:24:41Z

[Term]
id: GO:0072199
name: regulation of mesenchymal cell proliferation involved in ureter development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10]
synonym: "regulation of ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10]
synonym: "regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10]
is_a: GO:0010464 ! regulation of mesenchymal cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development
relationship: regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development
created_by: mah
creation_date: 2010-03-01T03:38:13Z

[Term]
id: GO:0072200
name: negative regulation of mesenchymal cell proliferation involved in ureter development
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10]
synonym: "negative regulation of ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10]
synonym: "negative regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development
is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development
relationship: negatively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development
created_by: mah
creation_date: 2010-03-01T03:42:31Z

[Term]
id: GO:0072201
name: negative regulation of mesenchymal cell proliferation
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0010464 ! regulation of mesenchymal cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010463 ! mesenchymal cell proliferation
relationship: negatively_regulates GO:0010463 ! mesenchymal cell proliferation
created_by: mah
creation_date: 2010-03-01T03:43:29Z

[Term]
id: GO:0072202
name: cell differentiation involved in metanephros development
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state." [GOC:mah, GOC:mtg_kidney_jan10]
is_a: GO:0061005 ! cell differentiation involved in kidney development
intersection_of: GO:0030154 ! cell differentiation
intersection_of: part_of GO:0001656 ! metanephros development
relationship: part_of GO:0001656 ! metanephros development
created_by: mah
creation_date: 2010-03-18T10:40:14Z

[Term]
id: GO:0072203
name: cell proliferation involved in metanephros development
namespace: biological_process
def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072111 ! cell proliferation involved in kidney development
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: part_of GO:0001656 ! metanephros development
relationship: part_of GO:0001656 ! metanephros development
created_by: mah
creation_date: 2010-03-18T10:42:27Z

[Term]
id: GO:0072204
name: cell-cell signaling involved in metanephros development
namespace: biological_process
def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10]
synonym: "cell-cell signalling involved in metanephros development" EXACT [GOC:mah]
is_a: GO:0060995 ! cell-cell signaling involved in kidney development
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: part_of GO:0001656 ! metanephros development
relationship: part_of GO:0001656 ! metanephros development
created_by: mah
creation_date: 2010-03-18T10:54:36Z

[Term]
id: GO:0072205
name: metanephric collecting duct development
namespace: biological_process
def: "The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10]
is_a: GO:0072044 ! collecting duct development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004737 ! metanephric collecting duct
relationship: part_of GO:0001656 ! metanephros development
relationship: results_in_development_of UBERON:0004737 ! metanephric collecting duct
created_by: mah
creation_date: 2010-03-18T11:15:37Z

[Term]
id: GO:0072207
name: metanephric epithelium development
namespace: biological_process
def: "The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10]
is_a: GO:0072073 ! kidney epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005108 ! metanephric epithelium
relationship: part_of GO:0001656 ! metanephros development
relationship: results_in_development_of UBERON:0005108 ! metanephric epithelium
created_by: mah
creation_date: 2010-03-18T11:50:37Z

[Term]
id: GO:0072208
name: metanephric smooth muscle tissue development
namespace: biological_process
def: "The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10]
is_a: GO:0072194 ! kidney smooth muscle tissue development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005109 ! metanephric smooth muscle tissue
relationship: part_of GO:0001656 ! metanephros development
relationship: results_in_development_of UBERON:0005109 ! metanephric smooth muscle tissue
created_by: mah
creation_date: 2010-03-18T11:51:59Z

[Term]
id: GO:0072210
name: metanephric nephron development
namespace: biological_process
def: "The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10]
is_a: GO:0072006 ! nephron development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005110 ! metanephric nephron
relationship: part_of GO:0001656 ! metanephros development
relationship: results_in_development_of UBERON:0005110 ! metanephric nephron
created_by: mah
creation_date: 2010-03-18T12:52:57Z

[Term]
id: GO:0072213
name: metanephric capsule development
namespace: biological_process
def: "The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10]
is_a: GO:0072127 ! renal capsule development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005137 ! metanephric capsule
relationship: part_of GO:0001656 ! metanephros development
relationship: results_in_development_of UBERON:0005137 ! metanephric capsule
created_by: mah
creation_date: 2010-03-18T01:25:19Z

[Term]
id: GO:0072214
name: metanephric cortex development
namespace: biological_process
def: "The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0060485 ! mesenchyme development
is_a: GO:0072055 ! renal cortex development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005113 ! metanephric cortex mesenchyme
relationship: part_of GO:0001656 ! metanephros development
relationship: results_in_development_of UBERON:0005113 ! metanephric cortex mesenchyme
created_by: mah
creation_date: 2010-03-18T01:29:49Z

[Term]
id: GO:0072215
name: regulation of metanephros development
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10]
is_a: GO:0090183 ! regulation of kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001656 ! metanephros development
relationship: regulates GO:0001656 ! metanephros development

[Term]
id: GO:0072216
name: positive regulation of metanephros development
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10]
is_a: GO:0072215 ! regulation of metanephros development
is_a: GO:0090184 ! positive regulation of kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001656 ! metanephros development
relationship: positively_regulates GO:0001656 ! metanephros development
created_by: mah
creation_date: 2010-03-18T01:40:12Z

[Term]
id: GO:0072217
name: negative regulation of metanephros development
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10]
is_a: GO:0072215 ! regulation of metanephros development
is_a: GO:0090185 ! negative regulation of kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001656 ! metanephros development
relationship: negatively_regulates GO:0001656 ! metanephros development
created_by: mah
creation_date: 2010-03-18T01:45:48Z

[Term]
id: GO:0072219
name: metanephric cortical collecting duct development
namespace: biological_process
def: "The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10]
is_a: GO:0072059 ! cortical collecting duct development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005115 ! metanephric cortical collecting duct
relationship: results_in_development_of UBERON:0005115 ! metanephric cortical collecting duct
created_by: mah
creation_date: 2010-03-18T03:34:52Z

[Term]
id: GO:0072234
name: metanephric nephron tubule development
namespace: biological_process
def: "The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072080 ! nephron tubule development
is_a: GO:0072170 ! metanephric tubule development
is_a: GO:0072243 ! metanephric nephron epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005146 ! metanephric nephron tubule
relationship: results_in_development_of UBERON:0005146 ! metanephric nephron tubule
created_by: mah
creation_date: 2010-03-18T03:41:23Z

[Term]
id: GO:0072243
name: metanephric nephron epithelium development
namespace: biological_process
def: "The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072009 ! nephron epithelium development
is_a: GO:0072207 ! metanephric epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005134 ! metanephric nephron epithelium
relationship: results_in_development_of UBERON:0005134 ! metanephric nephron epithelium
created_by: mah
creation_date: 2010-03-19T03:29:49Z

[Term]
id: GO:0072257
name: metanephric nephron tubule epithelial cell differentiation
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10]
is_a: GO:0072160 ! nephron tubule epithelial cell differentiation
is_a: GO:0072202 ! cell differentiation involved in metanephros development
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:1000123 ! metanephric nephron tubule epithelial cell
relationship: part_of GO:0072234 ! metanephric nephron tubule development
relationship: results_in_acquisition_of_features_of CL:1000123 ! metanephric nephron tubule epithelial cell
created_by: mah
creation_date: 2010-03-19T04:11:02Z

[Term]
id: GO:0072265
name: metanephric capsule morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10]
is_a: GO:0072128 ! renal capsule morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005137 ! metanephric capsule
relationship: part_of GO:0072213 ! metanephric capsule development
relationship: results_in_morphogenesis_of UBERON:0005137 ! metanephric capsule
created_by: mah
creation_date: 2010-03-30T02:54:49Z

[Term]
id: GO:0072266
name: metanephric capsule formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10]
is_a: GO:0072129 ! renal capsule formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005137 ! metanephric capsule
relationship: part_of GO:0072265 ! metanephric capsule morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0005137 ! metanephric capsule
created_by: mah
creation_date: 2010-03-30T02:56:35Z

[Term]
id: GO:0072268
name: pattern specification involved in metanephros development
namespace: biological_process
def: "Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10]
synonym: "metanephros pattern formation" RELATED [GOC:mtg_kidney_jan10]
synonym: "metanephros pattern specification" EXACT [GOC:mtg_kidney_jan10]
synonym: "pattern formation involved in metanephros development" RELATED [GOC:mtg_kidney_jan10]
is_a: GO:0061004 ! pattern specification involved in kidney development
intersection_of: GO:0007389 ! pattern specification process
intersection_of: part_of GO:0001656 ! metanephros development
relationship: part_of GO:0001656 ! metanephros development
created_by: mah
creation_date: 2010-03-30T03:06:30Z

[Term]
id: GO:0072273
name: metanephric nephron morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072028 ! nephron morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005110 ! metanephric nephron
relationship: part_of GO:0003338 ! metanephros morphogenesis
relationship: part_of GO:0072210 ! metanephric nephron development
relationship: results_in_morphogenesis_of UBERON:0005110 ! metanephric nephron
created_by: mah
creation_date: 2010-03-30T03:33:19Z

[Term]
id: GO:0072282
name: metanephric nephron tubule morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072078 ! nephron tubule morphogenesis
is_a: GO:0072173 ! metanephric tubule morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005146 ! metanephric nephron tubule
relationship: part_of GO:0072234 ! metanephric nephron tubule development
relationship: part_of GO:0072273 ! metanephric nephron morphogenesis
relationship: results_in_morphogenesis_of UBERON:0005146 ! metanephric nephron tubule
created_by: mah
creation_date: 2010-04-01T03:25:11Z

[Term]
id: GO:0072283
name: metanephric renal vesicle morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10]
is_a: GO:0072077 ! renal vesicle morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0005147 ! metanephric renal vesicle
relationship: part_of GO:0072273 ! metanephric nephron morphogenesis
relationship: results_in_morphogenesis_of UBERON:0005147 ! metanephric renal vesicle
created_by: mah
creation_date: 2010-04-01T03:28:00Z

[Term]
id: GO:0072285
name: mesenchymal to epithelial transition involved in metanephric renal vesicle formation
namespace: biological_process
def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle." [GOC:mtg_kidney_jan10]
is_a: GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis
is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation
intersection_of: GO:0060231 ! mesenchymal to epithelial transition
intersection_of: part_of GO:0072093 ! metanephric renal vesicle formation
relationship: part_of GO:0072093 ! metanephric renal vesicle formation
created_by: mah
creation_date: 2010-04-01T03:43:31Z

[Term]
id: GO:0072289
name: metanephric nephron tubule formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros." [GOC:mtg_kidney_jan10]
is_a: GO:0072079 ! nephron tubule formation
is_a: GO:0072174 ! metanephric tubule formation
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0005146 ! metanephric nephron tubule
relationship: part_of GO:0072282 ! metanephric nephron tubule morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0005146 ! metanephric nephron tubule
created_by: mah
creation_date: 2010-04-09T03:47:44Z

[Term]
id: GO:0072290
name: epithelial cell migration involved in metanephric nephron tubule morphogenesis
namespace: biological_process
def: "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis." [GOC:mtg_kidney_jan10]
is_a: GO:0035788 ! cell migration involved in metanephros development
is_a: GO:0072155 ! epithelial cell migration involved in nephron tubule morphogenesis
intersection_of: GO:0010631 ! epithelial cell migration
intersection_of: part_of GO:0072282 ! metanephric nephron tubule morphogenesis
relationship: part_of GO:0072282 ! metanephric nephron tubule morphogenesis
created_by: mah
creation_date: 2010-04-09T03:52:29Z

[Term]
id: GO:0072304
name: regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
namespace: biological_process
def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW []
synonym: "regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT []
is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
relationship: regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis
relationship: regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
created_by: mah
creation_date: 2010-04-09T05:03:41Z

[Term]
id: GO:0072305
name: negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
namespace: biological_process
def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW []
synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT []
is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
is_a: GO:1900212 ! negative regulation of mesenchymal cell apoptotic process involved in metanephros development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
relationship: negatively_regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis
relationship: negatively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
created_by: mah
creation_date: 2010-04-09T05:03:41Z

[Term]
id: GO:0072306
name: positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
namespace: biological_process
def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]
synonym: "positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW []
synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT []
is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
is_a: GO:1900213 ! positive regulation of mesenchymal cell apoptotic process involved in metanephros development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
relationship: positively_regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis
relationship: positively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
created_by: mah
creation_date: 2010-04-09T05:03:41Z

[Term]
id: GO:0072307
name: regulation of metanephric nephron tubule epithelial cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10]
is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation
relationship: regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation
created_by: mah
creation_date: 2010-04-09T05:03:41Z

[Term]
id: GO:0072308
name: negative regulation of metanephric nephron tubule epithelial cell differentiation
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10]
is_a: GO:0072183 ! negative regulation of nephron tubule epithelial cell differentiation
is_a: GO:0072307 ! regulation of metanephric nephron tubule epithelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation
relationship: negatively_regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation
created_by: mah
creation_date: 2010-04-09T05:03:41Z

[Term]
id: GO:0072309
name: mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis
namespace: biological_process
def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10]
is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis
relationship: part_of GO:0072273 ! metanephric nephron morphogenesis
created_by: mah
creation_date: 2010-04-09T05:03:41Z

[Term]
id: GO:0072329
name: monocarboxylic acid catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah]
is_a: GO:0032787 ! monocarboxylic acid metabolic process
is_a: GO:0046395 ! carboxylic acid catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:35757 ! monocarboxylic acid anion
relationship: has_primary_input CHEBI:35757 ! monocarboxylic acid anion
created_by: mah
creation_date: 2010-11-02T04:41:55Z

[Term]
id: GO:0072330
name: monocarboxylic acid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah]
synonym: "monocarboxylic acid anabolism" EXACT [GOC:mah]
synonym: "monocarboxylic acid biosynthesis" EXACT [GOC:mah]
synonym: "monocarboxylic acid formation" EXACT [GOC:mah]
synonym: "monocarboxylic acid synthesis" EXACT [GOC:mah]
is_a: GO:0032787 ! monocarboxylic acid metabolic process
is_a: GO:0046394 ! carboxylic acid biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:35757 ! monocarboxylic acid anion
relationship: has_primary_output CHEBI:35757 ! monocarboxylic acid anion
created_by: mah
creation_date: 2010-11-02T04:51:32Z

[Term]
id: GO:0072348
name: sulfur compound transport
namespace: biological_process
def: "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah]
synonym: "sulfur-containing compound transport" EXACT [GOC:mah]
is_a: GO:0006810 ! transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity
relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity
created_by: mah
creation_date: 2010-11-11T11:43:56Z

[Term]
id: GO:0072359
name: circulatory system development
namespace: biological_process
alt_id: GO:0072358
def: "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." [GOC:mah, UBERON:0001009]
subset: goslim_drosophila
synonym: "cardiovascular system development" NARROW []
is_a: GO:0048731 ! system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001009 ! circulatory system
relationship: results_in_development_of UBERON:0001009 ! circulatory system
created_by: mah
creation_date: 2010-11-16T11:27:39Z

[Term]
id: GO:0072360
name: vascular cord development
namespace: biological_process
def: "The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis." [GOC:mah, PMID:7084422, ZFA:0005077]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0006965 ! vascular cord
relationship: part_of GO:0072359 ! circulatory system development
relationship: results_in_development_of UBERON:0006965 ! vascular cord
created_by: mah
creation_date: 2010-11-16T11:46:55Z

[Term]
id: GO:0072384
name: organelle transport along microtubule
namespace: biological_process
def: "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." [GOC:mah]
synonym: "microtubule-based organelle localization" EXACT [GOC:rl]
is_a: GO:0010970 ! transport along microtubule
is_a: GO:0051656 ! establishment of organelle localization
intersection_of: GO:0046907 ! intracellular transport
intersection_of: has_primary_input GO:0043226 ! organelle
intersection_of: results_in_transport_along GO:0005874 ! microtubule
created_by: mah
creation_date: 2010-12-01T04:59:11Z

[Term]
id: GO:0072488
name: ammonium transmembrane transport
namespace: biological_process
alt_id: GO:0015696
def: "The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+." [GOC:mah]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "ammonia transport" BROAD []
synonym: "ammonium membrane transport" EXACT []
synonym: "ammonium transport" BROAD []
is_a: GO:0071705 ! nitrogen compound transport
is_a: GO:0098662 ! inorganic cation transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:28938 ! ammonium
intersection_of: results_in_transport_across GO:0016020 ! membrane
relationship: has_primary_input CHEBI:28938 ! ammonium
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22228" xsd:anyURI
created_by: mah
creation_date: 2010-12-10T10:29:57Z

[Term]
id: GO:0072520
name: seminiferous tubule development
namespace: biological_process
def: "The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa." [GOC:BHF, GOC:mah, UBERON:0001343]
is_a: GO:0035295 ! tube development
is_a: GO:0048608 ! reproductive structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001343 ! seminiferous tubule of testis
relationship: part_of GO:0008584 ! male gonad development
relationship: results_in_development_of UBERON:0001343 ! seminiferous tubule of testis
created_by: mah
creation_date: 2011-01-04T12:50:36Z

[Term]
id: GO:0072537
name: fibroblast activation
namespace: biological_process
def: "A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [CL:0000057, GOC:BHF, GOC:mah]
is_a: GO:0001775 ! cell activation
intersection_of: GO:0001775 ! cell activation
intersection_of: has_primary_input CL:0000057 ! fibroblast
relationship: has_primary_input CL:0000057 ! fibroblast
created_by: mah
creation_date: 2011-01-14T04:35:08Z

[Term]
id: GO:0072560
name: type B pancreatic cell maturation
namespace: biological_process
def: "A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF]
comment: These processes continue to 60 DPA in Gossypium spp.
synonym: "pancreatic B cell maturation" EXACT [CL:0000169, GOC:mah]
synonym: "pancreatic beta cell maturation" EXACT [CL:0000169, GOC:mah]
is_a: GO:0002071 ! glandular epithelial cell maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of CL:0000169 ! type B pancreatic cell
relationship: part_of GO:0003323 ! type B pancreatic cell development
relationship: results_in_maturation_of CL:0000169 ! type B pancreatic cell
created_by: mah
creation_date: 2011-01-27T01:57:14Z

[Term]
id: GO:0072575
name: epithelial cell proliferation involved in liver morphogenesis
namespace: biological_process
def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver." [GOC:BHF, GOC:mah]
is_a: GO:0050673 ! epithelial cell proliferation
intersection_of: GO:0050673 ! epithelial cell proliferation
intersection_of: part_of GO:0072576 ! liver morphogenesis
relationship: part_of GO:0072576 ! liver morphogenesis
created_by: mah
creation_date: 2011-02-02T03:37:50Z

[Term]
id: GO:0072576
name: liver morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of the liver are generated and organized." [GOC:mah]
is_a: GO:0022612 ! gland morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002107 ! liver
relationship: part_of GO:0001889 ! liver development
relationship: results_in_morphogenesis_of UBERON:0002107 ! liver
created_by: mah
creation_date: 2011-02-02T03:41:30Z

[Term]
id: GO:0072577
name: endothelial cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal." [CL:0000115, GOC:BHF, GOC:mah, GOC:mtg_apoptosis]
synonym: "apoptosis of endothelial cells" EXACT [GOC:mah]
synonym: "endothelial cell apoptosis" NARROW []
synonym: "endothelial cell programmed cell death by apoptosis" EXACT [GOC:mah]
synonym: "killing of endothelial cells" EXACT [GOC:mah]
synonym: "programmed cell death of endothelial cells by apoptosis" EXACT [GOC:mah]
synonym: "programmed cell death, endothelial cells" EXACT [GOC:mah]
is_a: GO:1904019 ! epithelial cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000115 ! endothelial cell
relationship: occurs_in CL:0000115 ! endothelial cell
created_by: mah
creation_date: 2011-02-02T03:56:24Z

[Term]
id: GO:0072592
name: oxygen metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving diatomic oxygen (O2)." [GOC:mah]
synonym: "diatomic oxygen metabolic process" EXACT [CHEBI:33263]
synonym: "oxygen metabolism" EXACT [GOC:mah]
is_a: GO:0044237 ! cellular metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:15379 ! dioxygen
relationship: has_primary_input_or_output CHEBI:15379 ! dioxygen
created_by: mah
creation_date: 2011-02-11T10:46:51Z

[Term]
id: GO:0072594
name: establishment of protein localization to organelle
namespace: biological_process
def: "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." [GOC:mah]
synonym: "establishment of protein localisation to organelle" EXACT [GOC:mah]
is_a: GO:0045184 ! establishment of protein localization
intersection_of: GO:0045184 ! establishment of protein localization
intersection_of: has_target_end_location GO:0043226 ! organelle
relationship: has_target_end_location GO:0043226 ! organelle
created_by: mah
creation_date: 2011-02-14T01:56:51Z

[Term]
id: GO:0072657
name: protein localization to membrane
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a specific location in a membrane." [GOC:mah]
subset: goslim_prokaryote
synonym: "protein localisation in membrane" EXACT [GOC:mah]
synonym: "protein localization in membrane" EXACT []
is_a: GO:0008104 ! protein localization
is_a: GO:0051668 ! localization within membrane
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0016020 ! membrane
created_by: mah
creation_date: 2011-02-14T02:35:18Z

[Term]
id: GO:0072659
name: protein localization to plasma membrane
namespace: biological_process
alt_id: GO:0072661
alt_id: GO:0090002
def: "A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane." [GOC:mah]
subset: goslim_generic
subset: goslim_pombe
synonym: "protein localisation in plasma membrane" RELATED [GOC:mah]
synonym: "protein localization in plasma membrane" RELATED []
synonym: "protein targeting to plasma membrane" RELATED []
synonym: "protein-plasma membrane targeting" RELATED [GOC:mah]
is_a: GO:0072657 ! protein localization to membrane
is_a: GO:1990778 ! protein localization to cell periphery
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005886 ! plasma membrane
intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure
relationship: has_target_end_location GO:0005886 ! plasma membrane
relationship: has_target_start_location GO:0005622 ! intracellular anatomical structure
created_by: tb
creation_date: 2009-07-10T10:29:23Z

[Term]
id: GO:0072665
name: protein localization to vacuole
namespace: biological_process
def: "A process in which a protein is transported to, or maintained at, a location in a vacuole." [GOC:ecd]
synonym: "protein localisation to vacuole" EXACT [GOC:mah]
is_a: GO:0033365 ! protein localization to organelle
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005773 ! vacuole
relationship: has_target_end_location GO:0005773 ! vacuole
created_by: mah
creation_date: 2011-02-14T02:55:35Z

[Term]
id: GO:0072666
name: establishment of protein localization to vacuole
namespace: biological_process
def: "The directed movement of a protein to a specific location in a vacuole." [GOC:mah]
synonym: "establishment of protein localisation to vacuole" EXACT [GOC:mah]
is_a: GO:0072594 ! establishment of protein localization to organelle
intersection_of: GO:0045184 ! establishment of protein localization
intersection_of: has_target_end_location GO:0005773 ! vacuole
relationship: has_target_end_location GO:0005773 ! vacuole
created_by: mah
creation_date: 2011-02-14T02:56:29Z

[Term]
id: GO:0072676
name: lymphocyte migration
namespace: biological_process
def: "The movement of a lymphocyte within or between different tissues and organs of the body." [CL:0000542, GOC:BHF, GOC:mah]
is_a: GO:0071674 ! mononuclear cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000542 ! lymphocyte
relationship: results_in_movement_of CL:0000542 ! lymphocyte
created_by: mah
creation_date: 2011-02-22T03:38:12Z

[Term]
id: GO:0072678
name: T cell migration
namespace: biological_process
def: "The movement of a T cell within or between different tissues and organs of the body." [CL:0000084, GOC:BHF, GOC:mah]
synonym: "T lymphocyte migration" EXACT [CL:0000084]
synonym: "T-cell migration" EXACT [CL:0000084]
synonym: "T-lymphocyte migration" EXACT [CL:0000084]
is_a: GO:0072676 ! lymphocyte migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000084 ! T cell
relationship: results_in_movement_of CL:0000084 ! T cell
created_by: mah
creation_date: 2011-02-22T03:40:40Z

[Term]
id: GO:0072697
name: protein localization to cell cortex
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, the cell cortex." [GOC:mah]
synonym: "protein localisation to cell cortex" EXACT [GOC:mah]
is_a: GO:1990778 ! protein localization to cell periphery
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005938 ! cell cortex
relationship: has_target_end_location GO:0005938 ! cell cortex
created_by: mah
creation_date: 2012-04-11T01:16:33Z

[Term]
id: GO:0072698
name: protein localization to microtubule cytoskeleton
namespace: biological_process
def: "A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton." [GOC:mah]
synonym: "protein localisation to microtubule cytoskeleton" EXACT [GOC:mah]
is_a: GO:0044380 ! protein localization to cytoskeleton
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0015630 ! microtubule cytoskeleton
relationship: has_target_end_location GO:0015630 ! microtubule cytoskeleton
created_by: mah
creation_date: 2012-04-11T01:19:35Z

[Term]
id: GO:0080090
name: regulation of primary metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [PMID:19211694]
is_a: GO:0019222 ! regulation of metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0044238 ! primary metabolic process
relationship: regulates GO:0044238 ! primary metabolic process
created_by: dhl
creation_date: 2009-04-22T04:30:52Z

[Term]
id: GO:0080134
name: regulation of response to stress
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl]
comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
subset: gocheck_do_not_manually_annotate
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006950 ! response to stress
relationship: regulates GO:0006950 ! response to stress
created_by: dhl
creation_date: 2009-05-06T04:51:28Z

[Term]
id: GO:0080154
name: regulation of fertilization
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:DHL, PMID:20478994]
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009566 ! fertilization
relationship: regulates GO:0009566 ! fertilization
created_by: dhl
creation_date: 2010-09-01T03:44:27Z

[Term]
id: GO:0085029
name: extracellular matrix assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of the extracellular matrix." [GOC:jl]
is_a: GO:0022607 ! cellular component assembly
is_a: GO:0030198 ! extracellular matrix organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0031012 ! extracellular matrix
relationship: results_in_assembly_of GO:0031012 ! extracellular matrix
created_by: jl
creation_date: 2010-07-14T12:52:49Z

[Term]
id: GO:0086001
name: cardiac muscle cell action potential
namespace: biological_process
def: "An action potential that occurs in a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
is_a: GO:0001508 ! action potential
intersection_of: GO:0001508 ! action potential
intersection_of: occurs_in CL:0000746 ! cardiac muscle cell
relationship: occurs_in CL:0000746 ! cardiac muscle cell
created_by: tb
creation_date: 2011-11-10T07:45:11Z

[Term]
id: GO:0086015
name: SA node cell action potential
namespace: biological_process
def: "An action potential that occurs in a sinoatrial node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "SA node cardiac muscle cell action potential" EXACT []
synonym: "SAN cardiac muscle cell action potential" EXACT []
synonym: "sinoatrial node cardiac muscle cell action potential" EXACT []
synonym: "sinus node cardiac muscle cell action potential" NARROW []
is_a: GO:0086001 ! cardiac muscle cell action potential
intersection_of: GO:0001508 ! action potential
intersection_of: occurs_in CL:1000409 ! myocyte of sinoatrial node
relationship: occurs_in CL:1000409 ! myocyte of sinoatrial node
relationship: part_of GO:0086018 ! SA node cell to atrial cardiac muscle cell signaling
created_by: tb
creation_date: 2011-11-10T08:50:15Z

[Term]
id: GO:0086016
name: AV node cell action potential
namespace: biological_process
def: "An action potential that occurs in an atrioventricular node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "atrioventricular node cardiac muscle cell action potential" EXACT []
synonym: "AV node cardiac muscle cell action potential" EXACT []
is_a: GO:0086001 ! cardiac muscle cell action potential
intersection_of: GO:0001508 ! action potential
intersection_of: occurs_in CL:1000410 ! myocyte of atrioventricular node
relationship: occurs_in CL:1000410 ! myocyte of atrioventricular node
relationship: part_of GO:0086027 ! AV node cell to bundle of His cell signaling
created_by: tb
creation_date: 2011-11-10T08:58:56Z

[Term]
id: GO:0086017
name: Purkinje myocyte action potential
namespace: biological_process
def: "An action potential that occurs in a Purkinje myocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
is_a: GO:0086001 ! cardiac muscle cell action potential
intersection_of: GO:0001508 ! action potential
intersection_of: occurs_in CL:0002068 ! Purkinje myocyte
relationship: occurs_in CL:0002068 ! Purkinje myocyte
relationship: part_of GO:0086029 ! Purkinje myocyte to ventricular cardiac muscle cell signaling
created_by: tb
creation_date: 2011-11-10T08:58:56Z

[Term]
id: GO:0086018
name: SA node cell to atrial cardiac muscle cell signaling
namespace: biological_process
def: "Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell signalling" EXACT []
synonym: "SA node cardiomyocyte to atrial cardiomyocyte signalling" EXACT []
synonym: "SAN cardiomyocyte to atrial cardiomyocyte signalling" EXACT []
synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling" EXACT []
synonym: "sinus node cardiomyocyte to atrial cardiomyocyte signalling" NARROW []
is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction
is_a: GO:0086070 ! SA node cell to atrial cardiac muscle cell communication
created_by: tb
creation_date: 2011-11-10T09:15:01Z

[Term]
id: GO:0086019
name: cell-cell signaling involved in cardiac conduction
namespace: biological_process
def: "Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "cell-cell signalling involved in cardiac conduction" EXACT [GOC:mah]
is_a: GO:0007267 ! cell-cell signaling
is_a: GO:0086065 ! cell communication involved in cardiac conduction
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: part_of GO:0061337 ! cardiac conduction
created_by: dph
creation_date: 2011-11-16T03:43:52Z

[Term]
id: GO:0086027
name: AV node cell to bundle of His cell signaling
namespace: biological_process
def: "Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "atrioventricular node to bundle of His cell signaling" EXACT []
synonym: "AV node cell to bundle of His cell signalling" EXACT [GOC:mah]
is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction
is_a: GO:0086067 ! AV node cell to bundle of His cell communication
created_by: tb
creation_date: 2011-11-11T02:02:14Z

[Term]
id: GO:0086029
name: Purkinje myocyte to ventricular cardiac muscle cell signaling
namespace: biological_process
def: "Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "Purkinje myocyte to ventricular cardiac muscle cell signalling" EXACT [GOC:mah]
is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction
is_a: GO:0086068 ! Purkinje myocyte to ventricular cardiac muscle cell communication
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: has_end_location CL:2000046 ! ventricular cardiac muscle cell
intersection_of: has_start_location CL:0002068 ! Purkinje myocyte
relationship: has_end_location CL:2000046 ! ventricular cardiac muscle cell
relationship: has_start_location CL:0002068 ! Purkinje myocyte
created_by: tb
creation_date: 2011-11-11T02:02:14Z

[Term]
id: GO:0086065
name: cell communication involved in cardiac conduction
namespace: biological_process
def: "Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
is_a: GO:0007154 ! cell communication
intersection_of: GO:0007154 ! cell communication
intersection_of: part_of GO:0061337 ! cardiac conduction
relationship: part_of GO:0061337 ! cardiac conduction
created_by: dph
creation_date: 2011-11-22T08:57:02Z

[Term]
id: GO:0086067
name: AV node cell to bundle of His cell communication
namespace: biological_process
def: "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "atrioventricular node cell to bundle of His cell communication" EXACT []
is_a: GO:0086065 ! cell communication involved in cardiac conduction
created_by: dph
creation_date: 2011-11-22T09:11:44Z

[Term]
id: GO:0086068
name: Purkinje myocyte to ventricular cardiac muscle cell communication
namespace: biological_process
def: "The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
is_a: GO:0086065 ! cell communication involved in cardiac conduction
created_by: dph
creation_date: 2011-11-22T09:14:49Z

[Term]
id: GO:0086070
name: SA node cell to atrial cardiac muscle cell communication
namespace: biological_process
def: "The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell communication" EXACT []
synonym: "SA node cardiomyocyte to atrial cardiomyocyte communication" EXACT []
synonym: "SAN cardiomyocyte to atrial cardiomyocyte communication" EXACT []
synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte communication" EXACT []
synonym: "sinus node cardiomyocyte to atrial cardiomyocyte communication" NARROW []
is_a: GO:0086065 ! cell communication involved in cardiac conduction
created_by: dph
creation_date: 2011-11-22T09:32:45Z

[Term]
id: GO:0090009
name: primitive streak formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0004341 ! primitive streak
relationship: part_of GO:0001702 ! gastrulation with mouth forming second
relationship: part_of GO:0009948 ! anterior/posterior axis specification
relationship: results_in_formation_of_anatomical_entity UBERON:0004341 ! primitive streak
created_by: tb
creation_date: 2009-07-29T10:31:31Z

[Term]
id: GO:0090063
name: positive regulation of microtubule nucleation
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb]
is_a: GO:0010968 ! regulation of microtubule nucleation
is_a: GO:0031116 ! positive regulation of microtubule polymerization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007020 ! microtubule nucleation
relationship: positively_regulates GO:0007020 ! microtubule nucleation
created_by: tb
creation_date: 2009-08-12T11:33:09Z

[Term]
id: GO:0090068
name: positive regulation of cell cycle process
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb]
is_a: GO:0010564 ! regulation of cell cycle process
is_a: GO:0045787 ! positive regulation of cell cycle
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0022402 ! cell cycle process
relationship: positively_regulates GO:0022402 ! cell cycle process
created_by: tb
creation_date: 2009-09-09T11:39:52Z

[Term]
id: GO:0090069
name: regulation of ribosome biogenesis
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb]
is_a: GO:0044087 ! regulation of cellular component biogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042254 ! ribosome biogenesis
relationship: regulates GO:0042254 ! ribosome biogenesis
created_by: tb
creation_date: 2009-09-11T10:32:17Z

[Term]
id: GO:0090070
name: positive regulation of ribosome biogenesis
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb]
is_a: GO:0044089 ! positive regulation of cellular component biogenesis
is_a: GO:0090069 ! regulation of ribosome biogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0042254 ! ribosome biogenesis
relationship: positively_regulates GO:0042254 ! ribosome biogenesis
created_by: tb
creation_date: 2009-09-11T10:32:17Z

[Term]
id: GO:0090071
name: negative regulation of ribosome biogenesis
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb]
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0090069 ! regulation of ribosome biogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042254 ! ribosome biogenesis
relationship: negatively_regulates GO:0042254 ! ribosome biogenesis
created_by: tb
creation_date: 2009-09-11T10:32:17Z

[Term]
id: GO:0090087
name: regulation of peptide transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb]
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0015833 ! peptide transport
relationship: regulates GO:0015833 ! peptide transport
created_by: tb
creation_date: 2009-10-23T11:21:38Z

[Term]
id: GO:0090091
name: positive regulation of extracellular matrix disassembly
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:dph, GOC:tb]
is_a: GO:0010715 ! regulation of extracellular matrix disassembly
is_a: GO:1903055 ! positive regulation of extracellular matrix organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0022617 ! extracellular matrix disassembly
relationship: positively_regulates GO:0022617 ! extracellular matrix disassembly
created_by: tb
creation_date: 2009-11-04T10:03:25Z

[Term]
id: GO:0090130
name: tissue migration
namespace: biological_process
def: "The process in which the population of cells that make up a tissue undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0032501 ! multicellular organismal process
created_by: tb
creation_date: 2009-12-07T03:13:55Z

[Term]
id: GO:0090132
name: epithelium migration
namespace: biological_process
def: "The process in which the population of cells that make up an epithelium undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0090130 ! tissue migration
created_by: tb
creation_date: 2009-12-07T03:19:34Z

[Term]
id: GO:0090138
name: regulation of actin cytoskeleton organization by cell-cell adhesion
namespace: biological_process
def: "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:ascb_2009, GOC:dph, GOC:tb]
synonym: "regulation of actin cytoskeleton organisation by cell-cell adhesion" EXACT [GOC:mah]
is_a: GO:0032956 ! regulation of actin cytoskeleton organization
is_a: GO:0098609 ! cell-cell adhesion
intersection_of: GO:0098609 ! cell-cell adhesion
intersection_of: regulates GO:0030036 ! actin cytoskeleton organization
created_by: tb
creation_date: 2009-12-08T02:05:00Z

[Term]
id: GO:0090150
name: establishment of protein localization to membrane
namespace: biological_process
def: "The directed movement of a protein to a specific location in a membrane." [GOC:ascb_2009, GOC:dph, GOC:tb]
synonym: "establishment of protein localisation in membrane" EXACT [GOC:mah]
synonym: "establishment of protein localization in membrane" EXACT []
is_a: GO:0045184 ! establishment of protein localization
is_a: GO:0051668 ! localization within membrane
intersection_of: GO:0045184 ! establishment of protein localization
intersection_of: has_target_end_location GO:0016020 ! membrane
created_by: tb
creation_date: 2009-12-08T03:18:51Z

[Term]
id: GO:0090162
name: establishment of epithelial cell polarity
namespace: biological_process
def: "The specification and formation of anisotropic intracellular organization of an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0030010 ! establishment of cell polarity
intersection_of: GO:0030010 ! establishment of cell polarity
intersection_of: occurs_in CL:0000066 ! epithelial cell
relationship: occurs_in CL:0000066 ! epithelial cell
created_by: tb
creation_date: 2009-12-08T08:58:27Z

[Term]
id: GO:0090166
name: Golgi disassembly
namespace: biological_process
def: "A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb]
synonym: "Golgi apparatus disassembly" EXACT []
is_a: GO:0007030 ! Golgi organization
is_a: GO:1903008 ! organelle disassembly
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0005794 ! Golgi apparatus
relationship: part_of GO:0048313 ! Golgi inheritance
relationship: results_in_disassembly_of GO:0005794 ! Golgi apparatus
created_by: tb
creation_date: 2009-12-08T09:15:11Z

[Term]
id: GO:0090168
name: Golgi reassembly
namespace: biological_process
def: "The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb]
synonym: "Golgi apparatus reassembly" EXACT []
is_a: GO:0007030 ! Golgi organization
is_a: GO:0022607 ! cellular component assembly
relationship: part_of GO:0048313 ! Golgi inheritance
created_by: tb
creation_date: 2009-12-08T09:15:11Z

[Term]
id: GO:0090170
name: regulation of Golgi inheritance
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:1903358 ! regulation of Golgi organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048313 ! Golgi inheritance
relationship: regulates GO:0048313 ! Golgi inheritance
created_by: tb
creation_date: 2009-12-11T10:21:59Z

[Term]
id: GO:0090171
name: chondrocyte morphogenesis
namespace: biological_process
def: "The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0000902 ! cell morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_maturation_of CL:0000138 ! chondrocyte
relationship: part_of GO:0002063 ! chondrocyte development
relationship: results_in_maturation_of CL:0000138 ! chondrocyte
created_by: tb
creation_date: 2009-12-11T10:36:02Z

[Term]
id: GO:0090174
name: organelle membrane fusion
namespace: biological_process
def: "The joining of two lipid bilayers to form a single organelle membrane." [GOC:ascb_2009, GOC:dph, GOC:tb]
is_a: GO:0048284 ! organelle fusion
is_a: GO:0061025 ! membrane fusion
intersection_of: GO:0061025 ! membrane fusion
intersection_of: results_in_fusion_of GO:0031090 ! organelle membrane
relationship: results_in_fusion_of GO:0031090 ! organelle membrane
created_by: tb
creation_date: 2009-12-11T11:44:58Z

[Term]
id: GO:0090183
name: regulation of kidney development
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf]
synonym: "regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001822 ! kidney development
relationship: regulates GO:0001822 ! kidney development
created_by: tb
creation_date: 2009-12-18T10:50:56Z

[Term]
id: GO:0090184
name: positive regulation of kidney development
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf]
synonym: "positive regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:0090183 ! regulation of kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001822 ! kidney development
relationship: positively_regulates GO:0001822 ! kidney development
created_by: tb
creation_date: 2009-12-18T10:52:01Z

[Term]
id: GO:0090185
name: negative regulation of kidney development
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf]
synonym: "negative regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0090183 ! regulation of kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001822 ! kidney development
relationship: negatively_regulates GO:0001822 ! kidney development
created_by: tb
creation_date: 2009-12-18T10:58:45Z

[Term]
id: GO:0090189
name: regulation of branching involved in ureteric bud morphogenesis
namespace: biological_process
def: "Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf]
is_a: GO:0060688 ! regulation of morphogenesis of a branching structure
is_a: GO:0090183 ! regulation of kidney development
is_a: GO:1905330 ! regulation of morphogenesis of an epithelium
is_a: GO:2000027 ! regulation of animal organ morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001658 ! branching involved in ureteric bud morphogenesis
relationship: regulates GO:0001658 ! branching involved in ureteric bud morphogenesis
created_by: tb
creation_date: 2009-12-18T11:11:17Z

[Term]
id: GO:0090190
name: positive regulation of branching involved in ureteric bud morphogenesis
namespace: biological_process
def: "Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf]
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis
is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis
relationship: positively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis
created_by: tb
creation_date: 2009-12-18T11:11:17Z

[Term]
id: GO:0090191
name: negative regulation of branching involved in ureteric bud morphogenesis
namespace: biological_process
def: "Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf]
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis
is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis
relationship: negatively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis
created_by: tb
creation_date: 2009-12-18T11:11:17Z

[Term]
id: GO:0090257
name: regulation of muscle system process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system." [GOC:dph, GOC:tb]
is_a: GO:0044057 ! regulation of system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003012 ! muscle system process
relationship: regulates GO:0003012 ! muscle system process
created_by: tb
creation_date: 2010-02-03T11:48:13Z

[Term]
id: GO:0090273
name: regulation of somatostatin secretion
namespace: biological_process
def: "Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF]
is_a: GO:0090276 ! regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070253 ! somatostatin secretion
relationship: regulates GO:0070253 ! somatostatin secretion
created_by: tb
creation_date: 2010-02-05T02:54:14Z

[Term]
id: GO:0090274
name: positive regulation of somatostatin secretion
namespace: biological_process
def: "Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF]
is_a: GO:0090273 ! regulation of somatostatin secretion
is_a: GO:0090277 ! positive regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0070253 ! somatostatin secretion
relationship: positively_regulates GO:0070253 ! somatostatin secretion
created_by: tb
creation_date: 2010-02-05T02:54:14Z

[Term]
id: GO:0090275
name: negative regulation of somatostatin secretion
namespace: biological_process
def: "Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF]
is_a: GO:0090273 ! regulation of somatostatin secretion
is_a: GO:0090278 ! negative regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0070253 ! somatostatin secretion
relationship: negatively_regulates GO:0070253 ! somatostatin secretion
created_by: tb
creation_date: 2010-02-05T02:54:14Z

[Term]
id: GO:0090276
name: regulation of peptide hormone secretion
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb]
is_a: GO:0002791 ! regulation of peptide secretion
is_a: GO:0046883 ! regulation of hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030072 ! peptide hormone secretion
relationship: regulates GO:0030072 ! peptide hormone secretion
created_by: tb
creation_date: 2010-02-05T02:56:39Z

[Term]
id: GO:0090277
name: positive regulation of peptide hormone secretion
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb]
is_a: GO:0002793 ! positive regulation of peptide secretion
is_a: GO:0046887 ! positive regulation of hormone secretion
is_a: GO:0090276 ! regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030072 ! peptide hormone secretion
relationship: positively_regulates GO:0030072 ! peptide hormone secretion
created_by: tb
creation_date: 2010-02-05T02:56:39Z

[Term]
id: GO:0090278
name: negative regulation of peptide hormone secretion
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb]
is_a: GO:0002792 ! negative regulation of peptide secretion
is_a: GO:0046888 ! negative regulation of hormone secretion
is_a: GO:0090276 ! regulation of peptide hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030072 ! peptide hormone secretion
relationship: negatively_regulates GO:0030072 ! peptide hormone secretion
created_by: tb
creation_date: 2010-02-05T02:56:39Z

[Term]
id: GO:0090299
name: regulation of neural crest formation
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." [GOC:tb]
is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014029 ! neural crest formation
relationship: regulates GO:0014029 ! neural crest formation
created_by: tb
creation_date: 2010-03-12T04:08:26Z

[Term]
id: GO:0090300
name: positive regulation of neural crest formation
namespace: biological_process
def: "Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:tb]
is_a: GO:0010718 ! positive regulation of epithelial to mesenchymal transition
is_a: GO:0090299 ! regulation of neural crest formation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014029 ! neural crest formation
relationship: positively_regulates GO:0014029 ! neural crest formation
created_by: tb
creation_date: 2010-03-12T04:08:26Z

[Term]
id: GO:0090301
name: negative regulation of neural crest formation
namespace: biological_process
def: "Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:tb]
is_a: GO:0010719 ! negative regulation of epithelial to mesenchymal transition
is_a: GO:0090299 ! regulation of neural crest formation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014029 ! neural crest formation
relationship: negatively_regulates GO:0014029 ! neural crest formation
created_by: tb
creation_date: 2010-03-12T04:08:26Z

[Term]
id: GO:0090304
name: nucleic acid metabolic process
namespace: biological_process
def: "Any cellular metabolic process involving nucleic acids." [GOC:dph, GOC:tb]
is_a: GO:0006139 ! nucleobase-containing compound metabolic process
is_a: GO:0043170 ! macromolecule metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:33696 ! nucleic acid
relationship: has_primary_input_or_output CHEBI:33696 ! nucleic acid
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26133" xsd:anyURI
created_by: tb
creation_date: 2010-04-07T10:18:47Z

[Term]
id: GO:0090316
name: positive regulation of intracellular protein transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb]
is_a: GO:0032388 ! positive regulation of intracellular transport
is_a: GO:0033157 ! regulation of intracellular protein transport
is_a: GO:0051222 ! positive regulation of protein transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006886 ! intracellular protein transport
relationship: positively_regulates GO:0006886 ! intracellular protein transport
created_by: tb
creation_date: 2010-04-16T03:45:07Z

[Term]
id: GO:0090317
name: negative regulation of intracellular protein transport
namespace: biological_process
def: "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb]
is_a: GO:0032387 ! negative regulation of intracellular transport
is_a: GO:0033157 ! regulation of intracellular protein transport
is_a: GO:0051224 ! negative regulation of protein transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006886 ! intracellular protein transport
relationship: negatively_regulates GO:0006886 ! intracellular protein transport
created_by: tb
creation_date: 2010-04-16T03:45:07Z

[Term]
id: GO:0090325
name: regulation of locomotion involved in locomotory behavior
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb]
is_a: GO:0040012 ! regulation of locomotion
is_a: GO:0050795 ! regulation of behavior
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0031987 ! locomotion involved in locomotory behavior
relationship: regulates GO:0031987 ! locomotion involved in locomotory behavior
created_by: tb
creation_date: 2010-05-14T10:24:29Z

[Term]
id: GO:0090326
name: positive regulation of locomotion involved in locomotory behavior
namespace: biological_process
def: "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb]
is_a: GO:0040017 ! positive regulation of locomotion
is_a: GO:0048520 ! positive regulation of behavior
is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior
intersection_of: GO:0050789 ! regulation of biological process
intersection_of: positively_regulates GO:0031987 ! locomotion involved in locomotory behavior
relationship: positively_regulates GO:0031987 ! locomotion involved in locomotory behavior
created_by: tb
creation_date: 2010-05-14T10:26:58Z

[Term]
id: GO:0090327
name: negative regulation of locomotion involved in locomotory behavior
namespace: biological_process
def: "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb]
is_a: GO:0040013 ! negative regulation of locomotion
is_a: GO:0048521 ! negative regulation of behavior
is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0031987 ! locomotion involved in locomotory behavior
relationship: negatively_regulates GO:0031987 ! locomotion involved in locomotory behavior
created_by: tb
creation_date: 2010-05-14T10:26:58Z

[Term]
id: GO:0090425
name: acinar cell differentiation
namespace: biological_process
def: "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini." [GOC:dph, GOC:tb]
is_a: GO:0002067 ! glandular epithelial cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000622 ! acinar cell
relationship: results_in_acquisition_of_features_of CL:0000622 ! acinar cell
created_by: tb
creation_date: 2012-05-04T09:24:48Z

[Term]
id: GO:0090435
name: protein localization to nuclear envelope
namespace: biological_process
def: "A process in which a protein is transported to, or maintained at, a location within a nuclear envelope." [GOC:tb]
synonym: "protein localization in nuclear envelope" EXACT []
is_a: GO:0034504 ! protein localization to nucleus
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005635 ! nuclear envelope
relationship: has_target_end_location GO:0005635 ! nuclear envelope
created_by: tb
creation_date: 2012-07-30T01:50:41Z

[Term]
id: GO:0090493
name: catecholamine uptake
namespace: biological_process
def: "The directed movement of catecholamine into a cell." [GOC:dph, GOC:tb]
is_a: GO:0051937 ! catecholamine transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:33567 ! catecholamine
intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure
intersection_of: has_target_start_location GO:0005576 ! extracellular region
relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure
relationship: has_target_start_location GO:0005576 ! extracellular region
created_by: tb
creation_date: 2012-10-17T11:06:17Z

[Term]
id: GO:0090497
name: mesenchymal cell migration
namespace: biological_process
def: "The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism." [GOC:dph, GOC:tb]
is_a: GO:0001667 ! ameboidal-type cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0008019 ! mesenchymal cell
relationship: results_in_movement_of CL:0008019 ! mesenchymal cell
created_by: tb
creation_date: 2012-10-17T12:08:17Z

[Term]
id: GO:0090596
name: sensory organ morphogenesis
namespace: biological_process
def: "Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:kmv, ISBN:978-0199210893]
is_a: GO:0009887 ! animal organ morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0000020 ! sense organ
relationship: part_of GO:0007423 ! sensory organ development
relationship: results_in_morphogenesis_of UBERON:0000020 ! sense organ
created_by: tb
creation_date: 2014-08-22T13:23:20Z

[Term]
id: GO:0090598
name: male anatomical structure morphogenesis
namespace: biological_process
def: "The processes by which anatomical structures that are only present in the male organism are generated and organized." [GOC:kmv, GOC:tb]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0014403 ! male anatomical structure
relationship: part_of GO:0046661 ! male sex differentiation
relationship: results_in_morphogenesis_of UBERON:0014403 ! male anatomical structure
created_by: tb
creation_date: 2014-08-22T13:29:45Z

[Term]
id: GO:0090685
name: RNA localization to nucleus
namespace: biological_process
def: "A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus." [GOC:mah, PMID:26305931]
synonym: "RNA localisation to nucleus" EXACT [GOC:mah]
is_a: GO:0006403 ! RNA localization
intersection_of: GO:0006403 ! RNA localization
intersection_of: has_target_end_location GO:0005634 ! nucleus
relationship: has_target_end_location GO:0005634 ! nucleus
created_by: tb
creation_date: 2016-07-19T17:00:49Z

[Term]
id: GO:0090741
name: pigment granule membrane
namespace: cellular_component
def: "Any membrane that is part of a pigment granule." [PMID:11294610]
is_a: GO:0030659 ! cytoplasmic vesicle membrane
is_a: GO:0098588 ! bounding membrane of organelle
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0048770 ! pigment granule
relationship: bounding_layer_of GO:0048770 ! pigment granule
relationship: part_of GO:0048770 ! pigment granule
created_by: tb
creation_date: 2017-05-16T22:33:39Z

[Term]
id: GO:0097014
name: ciliary plasm
namespace: cellular_component
def: "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium." [GOC:BHF, GOC:cilia, GOC:dos, PMID:17895364]
comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term "ciliary plasm" is not linked to "cytoplasm".
synonym: "cilial cytoplasm" RELATED []
synonym: "ciliary cytoplasm" RELATED []
synonym: "cilium cytoplasm" RELATED []
synonym: "cilium plasm" EXACT []
synonym: "microtubule-based flagellar cytoplasm" RELATED []
synonym: "microtubule-based flagellar matrix" NARROW []
synonym: "microtubule-based flagellum cytoplasm" RELATED []
synonym: "microtubule-based flagellum matrix" NARROW []
is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm
intersection_of: GO:0005737 ! cytoplasm
intersection_of: part_of GO:0005929 ! cilium
relationship: part_of GO:0005929 ! cilium
created_by: pr
creation_date: 2011-03-23T01:52:31Z

[Term]
id: GO:0097026
name: dendritic cell dendrite assembly
namespace: biological_process
def: "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, PMID:12200351]
comment: Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals.
synonym: "dendritic extension" BROAD []
is_a: GO:0120031 ! plasma membrane bounded cell projection assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0097511 ! dendritic cell dendrite
relationship: results_in_assembly_of GO:0097511 ! dendritic cell dendrite
created_by: pr
creation_date: 2011-03-31T04:52:53Z

[Term]
id: GO:0097028
name: dendritic cell differentiation
namespace: biological_process
def: "The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:pr]
comment: Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.
is_a: GO:1903131 ! mononuclear cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000451 ! dendritic cell
relationship: results_in_acquisition_of_features_of CL:0000451 ! dendritic cell
created_by: pr
creation_date: 2011-04-01T10:08:42Z

[Term]
id: GO:0097048
name: dendritic cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:BHF, GOC:mtg_apoptosis, PMID:15059845]
synonym: "dendritic cell apoptosis" NARROW []
is_a: GO:0071887 ! leukocyte apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000451 ! dendritic cell
relationship: occurs_in CL:0000451 ! dendritic cell
created_by: pr
creation_date: 2011-05-04T02:18:59Z

[Term]
id: GO:0097049
name: motor neuron apoptotic process
namespace: biological_process
def: "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:BHF, GOC:mtg_apoptosis, PMID:14523086]
synonym: "motoneuron apoptosis" EXACT []
synonym: "motor neuron apoptosis" NARROW []
is_a: GO:0051402 ! neuron apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000100 ! motor neuron
relationship: occurs_in CL:0000100 ! motor neuron
created_by: pr
creation_date: 2011-05-04T02:21:43Z

[Term]
id: GO:0097050
name: type B pancreatic cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF, GOC:mtg_apoptosis, PMID:16087305]
synonym: "pancreatic B cell apoptosis" EXACT []
synonym: "pancreatic beta cell apoptosis" EXACT []
synonym: "type B pancreatic cell apoptosis" NARROW []
is_a: GO:1904019 ! epithelial cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000169 ! type B pancreatic cell
relationship: occurs_in CL:0000169 ! type B pancreatic cell
created_by: pr
creation_date: 2011-05-04T02:24:38Z

[Term]
id: GO:0097060
name: synaptic membrane
namespace: cellular_component
def: "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:BHF, PMID:20410104]
subset: goslim_synapse
is_a: GO:0098590 ! plasma membrane region
intersection_of: GO:0098590 ! plasma membrane region
intersection_of: part_of GO:0045202 ! synapse
relationship: part_of GO:0045202 ! synapse
created_by: pr
creation_date: 2011-06-07T11:22:09Z

[Term]
id: GO:0097084
name: vascular associated smooth muscle cell development
namespace: biological_process
def: "The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [GOC:BHF]
synonym: "vascular smooth muscle cell development" EXACT []
is_a: GO:0055001 ! muscle cell development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of CL:0000359 ! vascular associated smooth muscle cell
relationship: part_of GO:0035886 ! vascular associated smooth muscle cell differentiation
relationship: results_in_development_of CL:0000359 ! vascular associated smooth muscle cell
created_by: pr
creation_date: 2011-06-20T04:03:08Z

[Term]
id: GO:0097152
name: mesenchymal cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [CL:0000134, GOC:mtg_apoptosis, GOC:yaf, PMID:18231833]
synonym: "mesenchymal cell apoptosis" NARROW []
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0008019 ! mesenchymal cell
relationship: occurs_in CL:0008019 ! mesenchymal cell
created_by: pr
creation_date: 2011-09-06T02:31:59Z

[Term]
id: GO:0097164
name: ammonium ion metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving the ammonium ion." [GOC:dhl, GOC:tb, PMID:14671018]
synonym: "ammonium ion metabolism" EXACT []
synonym: "ammonium metabolic process" RELATED []
is_a: GO:0006807 ! nitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:28938 ! ammonium
relationship: has_primary_input_or_output CHEBI:28938 ! ammonium
created_by: pr
creation_date: 2011-09-28T04:21:30Z

[Term]
id: GO:0097190
name: apoptotic signaling pathway
namespace: biological_process
alt_id: GO:0008624
def: "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis]
comment: This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.
synonym: "apoptotic signalling pathway" EXACT [GOC:mah]
synonym: "induction of apoptosis by extracellular signals" EXACT []
is_a: GO:0007165 ! signal transduction
relationship: part_of GO:0006915 ! apoptotic process
created_by: pr
creation_date: 2011-11-23T09:30:23Z

[Term]
id: GO:0097194
name: execution phase of apoptosis
namespace: biological_process
def: "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:mtg_apoptosis, PMID:21760595]
synonym: "apoptosis" NARROW []
synonym: "execution phase of apoptotic process" EXACT []
is_a: GO:0009987 ! cellular process
relationship: has_part GO:0032060 ! bleb assembly
relationship: part_of GO:0006915 ! apoptotic process
created_by: pr
creation_date: 2011-11-23T09:45:24Z

[Term]
id: GO:0097237
name: cellular response to toxic substance
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:pr]
created_by: pr
creation_date: 2012-02-02T12:23:31Z

[Term]
id: GO:0097254
name: renal tubular secretion
namespace: biological_process
def: "The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs." [GOC:rph, PMID:25287933, Wikipedia:Renal_secretion#Secretion]
is_a: GO:0003014 ! renal system process
is_a: GO:0007588 ! excretion
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI
created_by: pr
creation_date: 2012-03-05T02:03:58Z

[Term]
id: GO:0097284
name: hepatocyte apoptotic process
namespace: biological_process
def: "Any apoptotic process in a hepatocyte, the main structural component of the liver." [CL:0000182, GOC:jc, GOC:mtg_apoptosis, PMID:15856020]
synonym: "hepatocyte apoptosis" NARROW []
is_a: GO:1904019 ! epithelial cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000182 ! hepatocyte
relationship: occurs_in CL:0000182 ! hepatocyte
created_by: pr
creation_date: 2012-03-29T10:23:21Z

[Term]
id: GO:0097355
name: protein localization to heterochromatin
namespace: biological_process
def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin." [GOC:mah]
synonym: "protein localisation to heterochromatin" EXACT [GOC:mah]
is_a: GO:0071168 ! protein localization to chromatin
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0000792 ! heterochromatin
relationship: has_target_end_location GO:0000792 ! heterochromatin
created_by: pr
creation_date: 2012-07-03T03:19:07Z

[Term]
id: GO:0097360
name: chorionic trophoblast cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population." [CL:0011101, GOC:BHF, PMID:15150278]
is_a: GO:0008283 ! cell population proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0011101 ! chorionic trophoblast cell
relationship: acts_on_population_of CL:0011101 ! chorionic trophoblast cell
created_by: pr
creation_date: 2012-07-19T10:17:37Z

[Term]
id: GO:0097386
name: glial cell projection
namespace: cellular_component
def: "A prolongation or process extending from a glial cell." [GOC:mc]
synonym: "glial process" RELATED []
synonym: "glial projection" RELATED []
is_a: GO:0120025 ! plasma membrane bounded cell projection
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: GO:0120025 ! plasma membrane bounded cell projection
intersection_of: part_of CL:0000125 ! glial cell
relationship: part_of CL:0000125 ! glial cell
created_by: pr
creation_date: 2012-10-22T13:55:54Z

[Term]
id: GO:0097402
name: neuroblast migration
namespace: biological_process
def: "The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron." [CL:0000031, GOC:jc, PMID:15543145]
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000031 ! neuroblast (sensu Vertebrata)
relationship: results_in_movement_of CL:0000031 ! neuroblast (sensu Vertebrata)
created_by: pr
creation_date: 2012-10-29T08:24:37Z

[Term]
id: GO:0097427
name: microtubule bundle
namespace: cellular_component
def: "An arrangement of closely apposed microtubules running parallel to each other." [NIF_Subcellular:sao1872343973]
synonym: "microtubule fascicle" EXACT []
xref: NIF_Subcellular:sao1872343973
is_a: GO:0110165 ! cellular anatomical entity
relationship: has_part GO:0005874 ! microtubule
relationship: part_of GO:0005856 ! cytoskeleton
created_by: pr
creation_date: 2012-11-07T15:01:27Z

[Term]
id: GO:0097435
name: supramolecular fiber organization
namespace: biological_process
alt_id: GO:0043206
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:pr]
synonym: "extracellular fibril organisation" NARROW []
synonym: "extracellular fibril organization" NARROW []
synonym: "extracellular fibril organization and biogenesis" NARROW [GOC:mah]
synonym: "fibril organisation" RELATED []
synonym: "fibril organization" RELATED []
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0099512 ! supramolecular fiber
relationship: results_in_organization_of GO:0099512 ! supramolecular fiber
created_by: pr
creation_date: 2012-11-27T15:46:25Z

[Term]
id: GO:0097473
name: retinal rod cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000604, GOC:jc, PMID:17202487]
synonym: "rod photoreceptor apoptotic process" EXACT []
is_a: GO:0051402 ! neuron apoptotic process
is_a: GO:1990009 ! retinal cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000604 ! retinal rod cell
relationship: occurs_in CL:0000604 ! retinal rod cell
created_by: pr
creation_date: 2013-03-21T09:44:45Z

[Term]
id: GO:0097474
name: retinal cone cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000573, GOC:jc]
synonym: "cone photoreceptor apoptotic process" EXACT []
is_a: GO:0051402 ! neuron apoptotic process
is_a: GO:1990009 ! retinal cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000573 ! retinal cone cell
relationship: occurs_in CL:0000573 ! retinal cone cell
created_by: pr
creation_date: 2013-03-21T09:46:22Z

[Term]
id: GO:0097475
name: motor neuron migration
namespace: biological_process
def: "The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:yaf, PMID:20711475]
is_a: GO:0001764 ! neuron migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000100 ! motor neuron
relationship: results_in_movement_of CL:0000100 ! motor neuron
created_by: pr
creation_date: 2013-04-23T13:00:46Z

[Term]
id: GO:0097476
name: spinal cord motor neuron migration
namespace: biological_process
def: "The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [CL:0011001, GOC:yaf, PMID:20711475]
is_a: GO:0097475 ! motor neuron migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0011001 ! spinal cord motor neuron
relationship: results_in_movement_of CL:0011001 ! spinal cord motor neuron
created_by: pr
creation_date: 2013-04-23T13:03:46Z

[Term]
id: GO:0097511
name: dendritic cell dendrite
namespace: cellular_component
def: "A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, GOC:cjm, PMID:12200351]
is_a: GO:0120025 ! plasma membrane bounded cell projection
intersection_of: GO:0120025 ! plasma membrane bounded cell projection
intersection_of: part_of CL:0000451 ! dendritic cell
relationship: part_of CL:0000451 ! dendritic cell
created_by: pr
creation_date: 2013-10-16T13:02:25Z

[Term]
id: GO:0097512
name: cardiac myofibril
namespace: cellular_component
def: "A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:cjm, GOC:devbiol]
is_a: GO:0030016 ! myofibril
intersection_of: GO:0030016 ! myofibril
intersection_of: part_of CL:0000746 ! cardiac muscle cell
relationship: part_of CL:0000746 ! cardiac muscle cell
created_by: pr
creation_date: 2013-10-16T13:04:58Z

[Term]
id: GO:0097524
name: sperm plasma membrane
namespace: cellular_component
def: "A plasma membrane that is part of a sperm cell." [GOC:cjm]
is_a: GO:0005886 ! plasma membrane
intersection_of: GO:0005886 ! plasma membrane
intersection_of: part_of CL:0000019 ! sperm
relationship: part_of CL:0000019 ! sperm
created_by: pr
creation_date: 2013-10-18T11:31:17Z

[Term]
id: GO:0097529
name: myeloid leukocyte migration
namespace: biological_process
def: "The movement of a myeloid leukocyte within or between different tissues and organs of the body." [GOC:cvs, PMID:22342843, PMID:24157461]
is_a: GO:0050900 ! leukocyte migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000766 ! myeloid leukocyte
relationship: results_in_movement_of CL:0000766 ! myeloid leukocyte
created_by: pr
creation_date: 2013-11-11T13:59:43Z

[Term]
id: GO:0097534
name: lymphoid lineage cell migration
namespace: biological_process
def: "The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage." [GOC:pr, PMID:22342843]
synonym: "lymphoid lineage restricted progenitor cell migration" EXACT []
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000838 ! lymphoid lineage restricted progenitor cell
relationship: results_in_movement_of CL:0000838 ! lymphoid lineage restricted progenitor cell
created_by: pr
creation_date: 2013-11-28T10:47:15Z

[Term]
id: GO:0097576
name: vacuole fusion
namespace: biological_process
def: "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole." [GOC:pr, GOC:vw, Wikipedia:Vacuole]
is_a: GO:0007033 ! vacuole organization
is_a: GO:0048284 ! organelle fusion
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_fusion_of GO:0005773 ! vacuole
relationship: results_in_fusion_of GO:0005773 ! vacuole
created_by: pr
creation_date: 2014-02-28T09:49:31Z

[Term]
id: GO:0097708
name: intracellular vesicle
namespace: cellular_component
def: "Any vesicle that is part of the intracellular region." [GOC:vesicles]
is_a: GO:0031982 ! vesicle
is_a: GO:0043231 ! intracellular membrane-bounded organelle
intersection_of: GO:0031982 ! vesicle
intersection_of: part_of GO:0005622 ! intracellular anatomical structure
created_by: pr
creation_date: 2016-03-29T17:39:45Z

[Term]
id: GO:0097711
name: ciliary basal body-plasma membrane docking
namespace: biological_process
def: "The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane." [GOC:cilia, PMID:13978319, PMID:23348840, PMID:23530209, PMID:25686250, PMID:26981235, Reactome:R-HSA-5620912.1]
comment: Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella.
synonym: "anchoring of the basal body to the plasma membrane" RELATED []
synonym: "ciliary basal body docking" EXACT []
xref: Reactome:R-HSA-5620912.1
is_a: GO:0140056 ! organelle localization by membrane tethering
relationship: part_of GO:0060271 ! cilium assembly
created_by: pr
creation_date: 2016-08-05T16:12:33Z

[Term]
id: GO:0097712
name: vesicle targeting, trans-Golgi to periciliary membrane compartment
namespace: biological_process
def: "The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces." [GOC:cilia, PMID:20106869, PMID:23351793, PMID:24814148, PMID:26485645, Reactome:R-HSA-5620920.1]
is_a: GO:0048199 ! vesicle targeting, to, from or within Golgi
relationship: part_of GO:0060271 ! cilium assembly
created_by: pr
creation_date: 2016-08-05T16:16:28Z

[Term]
id: GO:0097722
name: sperm motility
namespace: biological_process
def: "Any process involved in the controlled movement of a sperm cell." [GOC:cilia, GOC:krc]
subset: gocheck_do_not_annotate
synonym: "sperm movement" EXACT []
is_a: GO:0022414 ! reproductive process
is_a: GO:0048870 ! cell motility
intersection_of: GO:0048870 ! cell motility
intersection_of: results_in_movement_of CL:0000019 ! sperm
relationship: results_in_movement_of CL:0000019 ! sperm
created_by: pr
creation_date: 2016-09-01T12:00:45Z

[Term]
id: GO:0097734
name: extracellular exosome biogenesis
namespace: biological_process
def: "The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:bf, GOC:PARL, PMID:19442504, PMID:25392495]
synonym: "exosome assembly or secretion" EXACT []
synonym: "exosome biogenesis" EXACT []
synonym: "exosome production" EXACT []
synonym: "ILV assembly" RELATED []
synonym: "intraluminal vesicle assembly" RELATED []
is_a: GO:0140112 ! extracellular vesicle biogenesis
created_by: pr
creation_date: 2016-10-03T14:35:25Z

[Term]
id: GO:0098523
name: neuromuscular junction of myotube
namespace: cellular_component
def: "A neuromuscular junction in which the target muscle cell is a myotube." [GOC:dos]
comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting the myotubes of skeletal muscle (AKA skeletal muscle fibers). Neuromuscular junctions targeting other muscle cell types exist in invertebrates such as the mononucleate somatic muscles of nematodes.
is_a: GO:0031594 ! neuromuscular junction
intersection_of: GO:0045202 ! synapse
intersection_of: overlaps CL:0000100 ! motor neuron
intersection_of: overlaps CL:0002372 ! myotube
relationship: overlaps CL:0002372 ! myotube
created_by: dos
creation_date: 2013-10-14T12:05:12Z

[Term]
id: GO:0098528
name: skeletal muscle fiber differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract." [GOC:dos]
is_a: GO:0014902 ! myotube differentiation
is_a: GO:0035914 ! skeletal muscle cell differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0008002 ! skeletal muscle fiber
relationship: results_in_acquisition_of_features_of CL:0008002 ! skeletal muscle fiber
created_by: dos
creation_date: 2013-10-15T14:00:34Z

[Term]
id: GO:0098542
name: defense response to other organism
namespace: biological_process
alt_id: GO:0009814
def: "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos]
subset: goslim_generic
subset: goslim_prokaryote
synonym: "defence response incompatible interaction" NARROW []
synonym: "defence response to pathogen, incompatible interaction" NARROW []
synonym: "defense response, incompatible interaction" NARROW []
synonym: "resistance response to pathogen" NARROW []
is_a: GO:0006952 ! defense response
is_a: GO:0051707 ! response to other organism
intersection_of: GO:0006952 ! defense response
intersection_of: has_primary_input NCBITaxon_Union:0000030
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22173" xsd:anyURI
created_by: dos
creation_date: 2013-11-11T12:59:11Z

[Term]
id: GO:0098588
name: bounding membrane of organelle
namespace: cellular_component
def: "The lipid bilayer that forms the outer-most layer of an organelle." [GOC:dos]
comment: Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes.
is_a: GO:0031090 ! organelle membrane
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0043226 ! organelle
relationship: bounding_layer_of GO:0043226 ! organelle
created_by: dos
creation_date: 2014-02-26T13:41:31Z

[Term]
id: GO:0098590
name: plasma membrane region
namespace: cellular_component
def: "A membrane that is a (regional) part of the plasma membrane." [GOC:dos]
comment: Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.
subset: gocheck_do_not_manually_annotate
synonym: "region of plasma membrane" EXACT []
is_a: GO:0016020 ! membrane
intersection_of: GO:0016020 ! membrane
intersection_of: part_of GO:0005886 ! plasma membrane
relationship: part_of GO:0005886 ! plasma membrane
created_by: dos
creation_date: 2014-03-06T11:55:32Z

[Term]
id: GO:0098609
name: cell-cell adhesion
namespace: biological_process
alt_id: GO:0016337
def: "The attachment of one cell to another cell via adhesion molecules." [GOC:dos]
synonym: "single organismal cell-cell adhesion" RELATED []
is_a: GO:0007155 ! cell adhesion
created_by: dos
creation_date: 2014-04-16T13:40:03Z

[Term]
id: GO:0098635
name: protein complex involved in cell-cell adhesion
namespace: cellular_component
def: "Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion." [GOC:dos]
is_a: GO:0098636 ! protein complex involved in cell adhesion
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: capable_of_part_of GO:0098609 ! cell-cell adhesion
relationship: capable_of_part_of GO:0098609 ! cell-cell adhesion

[Term]
id: GO:0098636
name: protein complex involved in cell adhesion
namespace: cellular_component
alt_id: GO:1990307
def: "Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell." [GOC:dos]
synonym: "cell adhesion complex" RELATED []
is_a: GO:0032991 ! protein-containing complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: capable_of_part_of GO:0007155 ! cell adhesion
relationship: capable_of_part_of GO:0007155 ! cell adhesion

[Term]
id: GO:0098642
name: network-forming collagen trimer
namespace: cellular_component
def: "A collagen trimer that forms networks." [PMID:21421911]
is_a: GO:0005581 ! collagen trimer
intersection_of: GO:0005581 ! collagen trimer
intersection_of: part_of GO:0098645 ! collagen network
relationship: part_of GO:0098645 ! collagen network

[Term]
id: GO:0098643
name: banded collagen fibril
namespace: cellular_component
def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:21421911]
is_a: GO:0098644 ! complex of collagen trimers
is_a: GO:0099512 ! supramolecular fiber

[Term]
id: GO:0098644
name: complex of collagen trimers
namespace: cellular_component
def: "A complex of collagen trimers such as a fibril or collagen network." [GOC:dos]
synonym: "Supramolecular aggregate of collagen" EXACT [PMID:19693541]
synonym: "Supramolecular collagen assembly" EXACT [PMID:21421911]
is_a: GO:0099080 ! supramolecular complex
is_a: PR:000050567 ! protein-containing material entity
relationship: has_part GO:0005581 ! collagen trimer
relationship: part_of GO:0062023 ! collagen-containing extracellular matrix

[Term]
id: GO:0098645
name: collagen network
namespace: cellular_component
def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911]
is_a: GO:0098644 ! complex of collagen trimers
is_a: GO:0099081 ! supramolecular polymer

[Term]
id: GO:0098651
name: basement membrane collagen trimer
namespace: cellular_component
def: "Any collagen timer that is part of a basement membrane." [GOC:dos, PMID:21421911]
is_a: GO:0005581 ! collagen trimer
intersection_of: GO:0005581 ! collagen trimer
intersection_of: part_of GO:0005604 ! basement membrane
relationship: part_of GO:0005604 ! basement membrane

[Term]
id: GO:0098655
name: monoatomic cation transmembrane transport
namespace: biological_process
alt_id: GO:0099132
def: "The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." [GOC:dos, GOC:vw]
synonym: "ATP hydrolysis coupled cation transmembrane transport" NARROW []
synonym: "cation transmembrane transport" BROAD []
is_a: GO:0006812 ! monoatomic cation transport
is_a: GO:0034220 ! monoatomic ion transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation
intersection_of: results_in_transport_across GO:0016020 ! membrane

[Term]
id: GO:0098657
name: import into cell
namespace: biological_process
def: "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:dos]
synonym: "uptake" BROAD []
is_a: GO:0006810 ! transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:24431 ! chemical entity
intersection_of: has_target_end_location GO:0005737 ! cytoplasm
intersection_of: has_target_start_location GO:0005576 ! extracellular region
relationship: has_primary_input CHEBI:24431 ! chemical entity
relationship: has_target_end_location GO:0005737 ! cytoplasm
relationship: has_target_start_location GO:0005576 ! extracellular region

[Term]
id: GO:0098660
name: inorganic ion transmembrane transport
namespace: biological_process
def: "The process in which an inorganic ion is transported across a membrane." [GOC:mah]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "inorganic ion membrane transport" EXACT []
synonym: "transmembrane inorganic ion transport" EXACT [GOC:dph, GOC:tb]
is_a: GO:0055085 ! transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:36914 ! inorganic ion
intersection_of: results_in_transport_across GO:0016020 ! membrane
relationship: has_primary_input CHEBI:36914 ! inorganic ion

[Term]
id: GO:0098661
name: inorganic anion transmembrane transport
namespace: biological_process
def: "The process in which an inorganic anion is transported across a membrane." [GOC:mah]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "inorganic anion membrane transport" EXACT []
synonym: "transmembrane inorganic anion transport" EXACT [GOC:dph, GOC:tb]
is_a: GO:0015698 ! inorganic anion transport
is_a: GO:0098660 ! inorganic ion transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:24834 ! inorganic anion
intersection_of: results_in_transport_across GO:0016020 ! membrane

[Term]
id: GO:0098662
name: inorganic cation transmembrane transport
namespace: biological_process
alt_id: GO:0015672
alt_id: GO:0072511
def: "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah]
comment: Note that this term is not intended for use in annotating lateral movement within membranes.
synonym: "divalent inorganic cation transport" NARROW []
synonym: "inorganic cation membrane transport" EXACT []
synonym: "monovalent inorganic cation transport" NARROW []
synonym: "transmembrane inorganic cation transport" EXACT [GOC:dph, GOC:tb]
is_a: GO:0098660 ! inorganic ion transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:36915 ! inorganic cation
intersection_of: results_in_transport_across GO:0016020 ! membrane
relationship: has_primary_input CHEBI:36915 ! inorganic cation

[Term]
id: GO:0098722
name: asymmetric stem cell division
namespace: biological_process
def: "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity." [GOC:dos, PMID:18513950]
is_a: GO:0008356 ! asymmetric cell division
is_a: GO:0017145 ! stem cell division
intersection_of: GO:0008356 ! asymmetric cell division
intersection_of: has_primary_input CL:0000034 ! stem cell

[Term]
id: GO:0098723
name: skeletal muscle myofibril
namespace: cellular_component
def: "A myofibril of a skeletal muscle fiber." [GOC:dos]
is_a: GO:0030016 ! myofibril
intersection_of: GO:0030016 ! myofibril
intersection_of: part_of CL:0008002 ! skeletal muscle fiber
relationship: part_of CL:0008002 ! skeletal muscle fiber

[Term]
id: GO:0098727
name: maintenance of cell number
namespace: biological_process
def: "Any process by which the numbers of cells of a particular type or in a tissue are maintained." [GOC:dos]
is_a: GO:0032502 ! developmental process

[Term]
id: GO:0098728
name: germline stem cell asymmetric division
namespace: biological_process
def: "The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes." [GOC:dos]
is_a: GO:0042078 ! germ-line stem cell division
is_a: GO:0098722 ! asymmetric stem cell division
intersection_of: GO:0008356 ! asymmetric cell division
intersection_of: has_primary_input CL:0000014 ! germ line stem cell

[Term]
id: GO:0098751
name: bone cell development
namespace: biological_process
def: "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dos]
comment: Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development.
subset: gocheck_do_not_annotate
is_a: GO:0048468 ! cell development
intersection_of: GO:0032502 ! developmental process
intersection_of: results_in_development_of CL:0001035 ! bone cell
relationship: part_of GO:0060348 ! bone development
relationship: results_in_development_of CL:0001035 ! bone cell

[Term]
id: GO:0098754
name: detoxification
namespace: biological_process
def: "Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:dos]
subset: goslim_generic
subset: goslim_pombe
subset: goslim_prokaryote
is_a: GO:0008150 ! biological process
relationship: part_of GO:0009636 ! response to toxic substance

[Term]
id: GO:0098773
name: skin epidermis development
namespace: biological_process
def: "The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure." [GOC:dos]
is_a: GO:0008544 ! epidermis development
is_a: GO:0060429 ! epithelium development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001003 ! skin epidermis
relationship: part_of GO:0043588 ! skin development
relationship: results_in_development_of UBERON:0001003 ! skin epidermis

[Term]
id: GO:0098793
name: presynapse
namespace: cellular_component
def: "The part of a synapse that is part of the presynaptic cell." [GOC:dos]
subset: goslim_synapse
synonym: "presynaptic terminal" EXACT []
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of CL:0000540 ! neuron
relationship: part_of GO:0045202 ! synapse

[Term]
id: GO:0098794
name: postsynapse
namespace: cellular_component
def: "The part of a synapse that is part of the post-synaptic cell." [GOC:dos]
subset: goslim_synapse
is_a: GO:0110165 ! cellular anatomical entity
relationship: part_of CL:0000000 ! cell
relationship: part_of GO:0045202 ! synapse

[Term]
id: GO:0098796
name: membrane protein complex
namespace: cellular_component
def: "Any protein complex that is part of a membrane." [GOC:dos]
subset: goslim_metagenomics
is_a: GO:0032991 ! protein-containing complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: part_of GO:0016020 ! membrane
relationship: part_of GO:0016020 ! membrane

[Term]
id: GO:0098797
name: plasma membrane protein complex
namespace: cellular_component
def: "Any protein complex that is part of the plasma membrane." [GOC:dos]
is_a: GO:0098796 ! membrane protein complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: part_of GO:0005886 ! plasma membrane
relationship: part_of GO:0005886 ! plasma membrane

[Term]
id: GO:0098801
name: regulation of renal system process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system." [GOC:dos]
is_a: GO:0044057 ! regulation of system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003014 ! renal system process
relationship: regulates GO:0003014 ! renal system process

[Term]
id: GO:0098813
name: nuclear chromosome segregation
namespace: biological_process
def: "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:dos]
is_a: GO:0007059 ! chromosome segregation

[Term]
id: GO:0098840
name: protein transport along microtubule
namespace: biological_process
def: "The directed movement of a protein along a microtubule, mediated by motor proteins." [PMID:25987607]
synonym: "microtubule-based protein transport" BROAD []
is_a: GO:0006886 ! intracellular protein transport
is_a: GO:0010970 ! transport along microtubule
is_a: GO:0099118 ! microtubule-based protein transport
intersection_of: GO:0046907 ! intracellular transport
intersection_of: has_primary_input PR:000000001 ! protein
intersection_of: results_in_transport_along GO:0005874 ! microtubule

[Term]
id: GO:0098858
name: actin-based cell projection
namespace: cellular_component
def: "A cell projection supported by an assembly of actin filaments, and which lacks microtubules." [PMID:15661519]
is_a: GO:0120025 ! plasma membrane bounded cell projection
relationship: has_part GO:0005884 ! actin filament

[Term]
id: GO:0098867
name: intramembranous bone growth
namespace: biological_process
def: "The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone." [PMID:26399686]
is_a: GO:0098868 ! bone growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: results_in_growth_of UBERON:0002514 ! intramembranous bone
relationship: results_in_growth_of UBERON:0002514 ! intramembranous bone

[Term]
id: GO:0098868
name: bone growth
namespace: biological_process
def: "The increase in size or mass of a bone that contributes to the shaping of that bone." [GOC:dos]
is_a: GO:0035265 ! organ growth
intersection_of: GO:0048589 ! developmental growth
intersection_of: results_in_growth_of UBERON:0001474 ! bone element
relationship: part_of GO:0060348 ! bone development
relationship: results_in_growth_of UBERON:0001474 ! bone element

[Term]
id: GO:0098871
name: postsynaptic actin cytoskeleton
namespace: cellular_component
def: "The actin cytoskeleton that is part of a postsynapse." [GOC:dos]
subset: goslim_synapse
is_a: GO:0015629 ! actin cytoskeleton
is_a: GO:0099571 ! postsynaptic cytoskeleton
intersection_of: GO:0015629 ! actin cytoskeleton
intersection_of: part_of GO:0098794 ! postsynapse

[Term]
id: GO:0098876
name: vesicle-mediated transport to the plasma membrane
namespace: biological_process
def: "The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis." [GOC:dos]
is_a: GO:0016192 ! vesicle-mediated transport
is_a: GO:0051668 ! localization within membrane
intersection_of: GO:0006810 ! transport
intersection_of: has_target_end_location GO:0005886 ! plasma membrane
intersection_of: process_has_causal_agent GO:0031982 ! vesicle
relationship: ends_with GO:0006887 ! exocytosis
relationship: has_target_end_location GO:0005886 ! plasma membrane

[Term]
id: GO:0098883
name: synapse pruning
namespace: biological_process
def: "A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared." [GOC:dos, PMID:12062020, PMID:18083105, PMID:22632716, PMID:29844190]
subset: goslim_synapse
synonym: "synapse clearance" EXACT [GOC:aruk, GOC:bc, PMID:22632716]
synonym: "synapse disassembly" EXACT syngo_official_label [PMID:12062020]
synonym: "synapse elimination" EXACT [GOC:aruk, GOC:bc, PMID:18083105, PMID:29844190]
synonym: "synapse removal" EXACT [GOC:aruk, GOC:bc, PMID:22632716]
is_a: GO:0050808 ! synapse organization
is_a: GO:0150146 ! cell junction disassembly
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0045202 ! synapse
relationship: results_in_disassembly_of GO:0045202 ! synapse

[Term]
id: GO:0098900
name: regulation of action potential
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8]
comment: The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term.
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0050789 ! regulation of biological process
intersection_of: regulates GO:0001508 ! action potential
relationship: regulates GO:0001508 ! action potential

[Term]
id: GO:0098901
name: regulation of cardiac muscle cell action potential
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:mtg_cardiac_conduct_nov11]
is_a: GO:0098900 ! regulation of action potential
intersection_of: GO:0050789 ! regulation of biological process
intersection_of: regulates GO:0086001 ! cardiac muscle cell action potential
relationship: regulates GO:0086001 ! cardiac muscle cell action potential

[Term]
id: GO:0098904
name: regulation of AV node cell action potential
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "regulation of atrioventricular node cardiac muscle cell action potential" EXACT []
synonym: "regulation of AV node cardiac muscle cell action potential" EXACT []
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0098901 ! regulation of cardiac muscle cell action potential
intersection_of: GO:0050789 ! regulation of biological process
intersection_of: regulates GO:0086016 ! AV node cell action potential
relationship: regulates GO:0086016 ! AV node cell action potential
created_by: tb
creation_date: 2011-11-10T08:58:56Z

[Term]
id: GO:0098906
name: regulation of Purkinje myocyte action potential
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0098901 ! regulation of cardiac muscle cell action potential
intersection_of: GO:0050789 ! regulation of biological process
intersection_of: regulates GO:0086017 ! Purkinje myocyte action potential
relationship: regulates GO:0086017 ! Purkinje myocyte action potential
created_by: tb
creation_date: 2011-11-10T08:58:56Z

[Term]
id: GO:0098907
name: regulation of SA node cell action potential
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]
synonym: "regulation of SA node cardiac muscle cell action potential" EXACT []
synonym: "regulation of SAN cardiac muscle cell action potential" EXACT []
synonym: "regulation of sinoatrial node cardiac muscle cell action potential" EXACT []
synonym: "regulation of sinus node cardiac muscle cell action potential" NARROW []
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0098901 ! regulation of cardiac muscle cell action potential
intersection_of: GO:0050789 ! regulation of biological process
intersection_of: regulates GO:0086015 ! SA node cell action potential
relationship: regulates GO:0086015 ! SA node cell action potential
created_by: tb
creation_date: 2011-11-10T08:50:15Z

[Term]
id: GO:0098908
name: regulation of neuronal action potential
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dph, GOC:isa_complete, GOC:tb]
synonym: "generation of action potential" RELATED [GOC:dph, GOC:tb]
is_a: GO:0051969 ! regulation of transmission of nerve impulse
is_a: GO:0098900 ! regulation of action potential
intersection_of: GO:0050789 ! regulation of biological process
intersection_of: regulates GO:0019228 ! neuronal action potential
relationship: regulates GO:0019228 ! neuronal action potential

[Term]
id: GO:0098916
name: anterograde trans-synaptic signaling
namespace: biological_process
def: "Cell-cell signaling from pre to post-synapse, across the synaptic cleft." [GOC:dos]
is_a: GO:0099537 ! trans-synaptic signaling
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: has_end_location GO:0098794 ! postsynapse
intersection_of: has_start_location GO:0098793 ! presynapse
relationship: has_end_location GO:0098794 ! postsynapse
relationship: has_start_location GO:0098793 ! presynapse

[Term]
id: GO:0098917
name: retrograde trans-synaptic signaling
namespace: biological_process
def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft." [GOC:dos]
is_a: GO:0099537 ! trans-synaptic signaling
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: has_end_location GO:0098793 ! presynapse
intersection_of: has_start_location GO:0098794 ! postsynapse
relationship: has_end_location GO:0098793 ! presynapse
relationship: has_start_location GO:0098794 ! postsynapse

[Term]
id: GO:0098920
name: retrograde trans-synaptic signaling by lipid
namespace: biological_process
def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand." [GOC:dos]
subset: goslim_synapse
is_a: GO:0098917 ! retrograde trans-synaptic signaling
is_a: GO:0099541 ! trans-synaptic signaling by lipid
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: has_end_location GO:0098793 ! presynapse
intersection_of: has_start_location GO:0098794 ! postsynapse
intersection_of: process_has_causal_agent CHEBI:18059 ! lipid

[Term]
id: GO:0098926
name: postsynaptic signal transduction
namespace: biological_process
def: "Signal transduction in which the initial step occurs in a postsynapse." [GOC:dos]
subset: goslim_synapse
synonym: "postsynaptic signaling pathway" EXACT syngo_official_label []
is_a: GO:0007165 ! signal transduction
intersection_of: GO:0007165 ! signal transduction
intersection_of: has_start_location GO:0098794 ! postsynapse
relationship: has_start_location GO:0098794 ! postsynapse
relationship: part_of GO:0099536 ! synaptic signaling

[Term]
id: GO:0098928
name: presynaptic signal transduction
namespace: biological_process
def: "Signal transduction in which the initial step occurs in a presynapse." [GOC:dos]
subset: goslim_synapse
synonym: "presynaptic signaling pathway" EXACT syngo_official_label []
is_a: GO:0007165 ! signal transduction
intersection_of: GO:0007165 ! signal transduction
intersection_of: has_start_location GO:0098793 ! presynapse
relationship: has_start_location GO:0098793 ! presynapse

[Term]
id: GO:0098974
name: postsynaptic actin cytoskeleton organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton." [GOC:dos]
subset: goslim_synapse
is_a: GO:0030036 ! actin cytoskeleton organization
is_a: GO:0099188 ! postsynaptic cytoskeleton organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0098871 ! postsynaptic actin cytoskeleton
relationship: results_in_organization_of GO:0098871 ! postsynaptic actin cytoskeleton

[Term]
id: GO:0098975
name: postsynapse of neuromuscular junction
namespace: cellular_component
def: "The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma." [GOC:dos, Wikipedia:Neuromuscular_junction&oldid=723623502]
is_a: GO:0098794 ! postsynapse
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: GO:0098794 ! postsynapse
intersection_of: part_of CL:0000187 ! muscle cell
intersection_of: part_of GO:0031594 ! neuromuscular junction
relationship: part_of CL:0000187 ! muscle cell
relationship: part_of GO:0031594 ! neuromuscular junction

[Term]
id: GO:0098981
name: cholinergic synapse
namespace: cellular_component
def: "A synapse that uses acetylcholine as a neurotransmitter." [GOC:dos]
subset: goslim_synapse
is_a: GO:0045202 ! synapse
intersection_of: GO:0045202 ! synapse
intersection_of: capable_of GO:0007271 ! synaptic transmission, cholinergic
relationship: capable_of GO:0007271 ! synaptic transmission, cholinergic

[Term]
id: GO:0098992
name: neuronal dense core vesicle
namespace: cellular_component
def: "A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals." [GOC:dos, ISBN:978-0-07-181001-2, Wikipedia:Neuropeptide&oldid=713905176]
subset: goslim_synapse
is_a: GO:0031045 ! dense core granule
intersection_of: GO:0031045 ! dense core granule
intersection_of: part_of CL:0000540 ! neuron
relationship: part_of CL:0000540 ! neuron

[Term]
id: GO:0099003
name: vesicle-mediated transport in synapse
namespace: biological_process
def: "Any vesicle-mediated transport that occurs in a synapse." [GOC:dos]
subset: goslim_synapse
is_a: GO:0016192 ! vesicle-mediated transport
intersection_of: GO:0016192 ! vesicle-mediated transport
intersection_of: occurs_in GO:0045202 ! synapse
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: occurs_in GO:0045202 ! synapse
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa

[Term]
id: GO:0099012
name: neuronal dense core vesicle membrane
namespace: cellular_component
def: "The lipid bilayer surrounding a neuronal dense core vesicle." [GOC:dos]
subset: goslim_synapse
is_a: GO:0032127 ! dense core granule membrane
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0098992 ! neuronal dense core vesicle
relationship: bounding_layer_of GO:0098992 ! neuronal dense core vesicle
relationship: part_of GO:0098992 ! neuronal dense core vesicle

[Term]
id: GO:0099014
name: neuronal dense core vesicle organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle." [GOC:dos]
is_a: GO:0061109 ! dense core granule organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0098992 ! neuronal dense core vesicle
relationship: results_in_organization_of GO:0098992 ! neuronal dense core vesicle

[Term]
id: GO:0099054
name: presynapse assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form a presynapse." [GOC:bf, GOC:dos, GOC:PARL, PMID:24449494]
subset: goslim_synapse
synonym: "presynapse biogenesis" EXACT [GOC:mah]
synonym: "presynaptic terminal assembly" EXACT [PMID:24449494]
is_a: GO:0022607 ! cellular component assembly
is_a: GO:0099172 ! presynapse organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_assembly_of GO:0098793 ! presynapse
relationship: part_of GO:0007416 ! synapse assembly
relationship: results_in_assembly_of GO:0098793 ! presynapse

[Term]
id: GO:0099068
name: postsynapse assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:bf, GOC:dos, GOCL:PARL]
synonym: "postsynapse biogenesis" EXACT [GOC:mah]
is_a: GO:0022607 ! cellular component assembly
is_a: GO:0099173 ! postsynapse organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_assembly_of GO:0098794 ! postsynapse
relationship: part_of GO:0007416 ! synapse assembly
relationship: results_in_assembly_of GO:0098794 ! postsynapse

[Term]
id: GO:0099080
name: supramolecular complex
namespace: cellular_component
def: "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." [GOC:dos]
is_a: GO:0110165 ! cellular anatomical entity

[Term]
id: GO:0099081
name: supramolecular polymer
namespace: cellular_component
def: "A polymeric supramolecular structure." [GOC:dos]
is_a: GO:0099080 ! supramolecular complex
intersection_of: GO:0099080 ! supramolecular complex
intersection_of: has_characteristic PATO:0015006 ! polymeric
relationship: has_characteristic PATO:0015006 ! polymeric

[Term]
id: GO:0099082
name: retrograde trans-synaptic signaling by neuropeptide
namespace: biological_process
def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629]
subset: goslim_synapse
is_a: GO:0098917 ! retrograde trans-synaptic signaling
is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: has_end_location GO:0098793 ! presynapse
intersection_of: has_start_location GO:0098794 ! postsynapse
intersection_of: process_has_causal_agent CHEBI:16670 ! peptide

[Term]
id: GO:0099083
name: retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission
namespace: biological_process
def: "Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide
is_a: GO:0099551 ! trans-synaptic signaling by neuropeptide, modulating synaptic transmission
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: has_end_location GO:0098793 ! presynapse
intersection_of: has_start_location GO:0098794 ! postsynapse
intersection_of: process_has_causal_agent CHEBI:16670 ! peptide
intersection_of: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099098
name: microtubule polymerization based movement
namespace: biological_process
def: "The movement of a cellular component as a result of microtubule polymerization." [GOC:cjm, ISBN:0815316194]
is_a: GO:0007018 ! microtubule-based movement
intersection_of: GO:0007018 ! microtubule-based movement
intersection_of: has_part GO:0046785 ! microtubule polymerization
relationship: has_part GO:0046785 ! microtubule polymerization

[Term]
id: GO:0099111
name: microtubule-based transport
namespace: biological_process
def: "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194]
is_a: GO:0006810 ! transport
intersection_of: GO:0006810 ! transport
intersection_of: process_has_causal_agent GO:0005874 ! microtubule
relationship: process_has_causal_agent GO:0005874 ! microtubule

[Term]
id: GO:0099112
name: microtubule polymerization based protein transport
namespace: biological_process
def: "The transport of a protein driven by polymerization of a microtubule to which it is attached." [GOC:dos, GOC:vw, PMID:11018050]
is_a: GO:0007017 ! microtubule-based process
is_a: GO:0045184 ! establishment of protein localization
is_a: GO:0046907 ! intracellular transport
is_a: GO:0071702 ! organic substance transport
is_a: GO:0099111 ! microtubule-based transport
intersection_of: GO:0046907 ! intracellular transport
intersection_of: has_part GO:0046785 ! microtubule polymerization
intersection_of: has_primary_input CHEBI:36080 ! protein
intersection_of: process_has_causal_agent GO:0005874 ! microtubule
relationship: has_part GO:0046785 ! microtubule polymerization

[Term]
id: GO:0099118
name: microtubule-based protein transport
namespace: biological_process
def: "A microtubule-based process that results in the transport of proteins." [GOC:vw]
is_a: GO:0007017 ! microtubule-based process
is_a: GO:0015031 ! protein transport
is_a: GO:0099111 ! microtubule-based transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input PR:000000001 ! protein
intersection_of: process_has_causal_agent GO:0005874 ! microtubule

[Term]
id: GO:0099140
name: presynaptic actin cytoskeleton organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton." [GOC:dos]
subset: goslim_synapse
is_a: GO:0030036 ! actin cytoskeleton organization
is_a: GO:0099187 ! presynaptic cytoskeleton organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0099143 ! presynaptic actin cytoskeleton
relationship: results_in_organization_of GO:0099143 ! presynaptic actin cytoskeleton
created_by: dos
creation_date: 2017-06-09T18:34:19Z

[Term]
id: GO:0099143
name: presynaptic actin cytoskeleton
namespace: cellular_component
def: "The actin cytoskeleton that is part of a presynapse." [GOC:dos]
subset: goslim_synapse
is_a: GO:0015629 ! actin cytoskeleton
is_a: GO:0099569 ! presynaptic cytoskeleton
intersection_of: GO:0015629 ! actin cytoskeleton
intersection_of: part_of GO:0098793 ! presynapse
created_by: dos
creation_date: 2017-06-09T18:36:19Z

[Term]
id: GO:0099156
name: cell-cell signaling via exosome
namespace: biological_process
def: "Cell-cell signaling in which the ligand is carried between cells by an exosome." [GOC:dos, PMID:19837038]
synonym: "exosome mediated" EXACT []
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: process_has_causal_agent GO:0070062 ! extracellular exosome
relationship: process_has_causal_agent GO:0070062 ! extracellular exosome
created_by: dos
creation_date: 2017-07-05T16:40:45Z

[Term]
id: GO:0099157
name: trans-synaptic signaling via exosome
namespace: biological_process
def: "Transynaptic signaling in which the ligand is carried across the synapse by an exosome." [GOC:dos, PMID:19837038]
subset: goslim_synapse
synonym: "exosome mediated transynaptic signalling" EXACT []
synonym: "trans-synaptic signalling via exosome" EXACT []
is_a: GO:0099156 ! cell-cell signaling via exosome
is_a: GO:0099537 ! trans-synaptic signaling
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: process_has_causal_agent GO:0070062 ! extracellular exosome
created_by: dos
creation_date: 2017-07-05T16:49:44Z

[Term]
id: GO:0099170
name: postsynaptic modulation of chemical synaptic transmission
namespace: biological_process
def: "Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission." [GOC:dos]
subset: goslim_synapse
is_a: GO:0050804 ! modulation of chemical synaptic transmission
intersection_of: GO:0050804 ! modulation of chemical synaptic transmission
intersection_of: occurs_in GO:0098794 ! postsynapse
relationship: occurs_in GO:0098794 ! postsynapse
created_by: dos
creation_date: 2017-09-11T17:09:17Z

[Term]
id: GO:0099171
name: presynaptic modulation of chemical synaptic transmission
namespace: biological_process
def: "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission." [GOC:dos]
subset: goslim_synapse
is_a: GO:0050804 ! modulation of chemical synaptic transmission
intersection_of: GO:0050804 ! modulation of chemical synaptic transmission
intersection_of: occurs_in GO:0098793 ! presynapse
relationship: occurs_in GO:0098793 ! presynapse
created_by: dos
creation_date: 2017-09-11T17:09:31Z

[Term]
id: GO:0099172
name: presynapse organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse." [GOC:dos]
subset: goslim_synapse
synonym: "presynapse development" EXACT []
synonym: "presynapse morphogenesis" RELATED [GOC:BHF]
synonym: "presynapse organisation" EXACT []
synonym: "presynapse organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_organization_of GO:0098793 ! presynapse
relationship: part_of GO:0050808 ! synapse organization
relationship: results_in_organization_of GO:0098793 ! presynapse

[Term]
id: GO:0099173
name: postsynapse organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse." [GOC:dos]
subset: goslim_synapse
synonym: "postsynapse development" EXACT []
synonym: "postsynapse morphogenesis" RELATED [GOC:BHF]
synonym: "postsynapse organisation" EXACT []
synonym: "postsynapse organization and biogenesis" RELATED [GOC:mah]
is_a: GO:0016043 ! cellular component organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_organization_of GO:0098794 ! postsynapse
relationship: part_of GO:0050808 ! synapse organization
relationship: results_in_organization_of GO:0098794 ! postsynapse

[Term]
id: GO:0099174
name: regulation of presynapse organization
namespace: biological_process
def: "Any process that modulates the physical form of a presynapse." [GOC:ai, GOC:dph, GOC:tb]
subset: goslim_synapse
synonym: "regulation of presynapse organisation" EXACT [GOC:mah]
synonym: "regulation of presynapse organization and biogenesis" RELATED [GOC:mah]
synonym: "regulation of presynapse structure" EXACT []
is_a: GO:0050807 ! regulation of synapse organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0099172 ! presynapse organization
relationship: regulates GO:0099172 ! presynapse organization

[Term]
id: GO:0099175
name: regulation of postsynapse organization
namespace: biological_process
def: "Any process that modulates the physical form of a postsynapse." [GOC:ai, GOC:dph, GOC:tb]
subset: goslim_synapse
synonym: "regulation of postsynapse organisation" EXACT [GOC:mah]
synonym: "regulation of postsynapse organization and biogenesis" RELATED [GOC:mah]
synonym: "regulation of postsynapse structure" EXACT []
is_a: GO:0050807 ! regulation of synapse organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0099173 ! postsynapse organization
relationship: regulates GO:0099173 ! postsynapse organization

[Term]
id: GO:0099177
name: regulation of trans-synaptic signaling
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." [GOC:dos]
is_a: GO:0010646 ! regulation of cell communication
is_a: GO:0023051 ! regulation of signaling
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0099537 ! trans-synaptic signaling
relationship: regulates GO:0099537 ! trans-synaptic signaling

[Term]
id: GO:0099187
name: presynaptic cytoskeleton organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton." [GOC:dos]
is_a: GO:0007010 ! cytoskeleton organization
intersection_of: GO:0009987 ! cellular process
intersection_of: results_in_organization_of GO:0099569 ! presynaptic cytoskeleton
relationship: part_of GO:0099172 ! presynapse organization
relationship: results_in_organization_of GO:0099569 ! presynaptic cytoskeleton
created_by: dos
creation_date: 2017-12-20T15:05:34Z

[Term]
id: GO:0099188
name: postsynaptic cytoskeleton organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton." [GOC:dos]
subset: goslim_synapse
is_a: GO:0007010 ! cytoskeleton organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0099571 ! postsynaptic cytoskeleton
relationship: part_of GO:0099173 ! postsynapse organization
relationship: results_in_organization_of GO:0099571 ! postsynaptic cytoskeleton
created_by: dos
creation_date: 2017-12-20T15:06:57Z

[Term]
id: GO:0099500
name: vesicle fusion to plasma membrane
namespace: biological_process
def: "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space." [GOC:aruk, GOC:bc, ISBN:0071120009, PMID:18618940]
is_a: GO:0006906 ! vesicle fusion
is_a: GO:0140029 ! exocytic process
intersection_of: GO:0061025 ! membrane fusion
intersection_of: part_of GO:0006887 ! exocytosis
intersection_of: results_in_fusion_of GO:0012506 ! vesicle membrane
intersection_of: results_in_fusion_of GO:0098590 ! plasma membrane region
relationship: results_in_fusion_of GO:0098590 ! plasma membrane region

[Term]
id: GO:0099501
name: exocytic vesicle membrane
namespace: cellular_component
def: "The lipid bilayer surrounding an exocytic vesicle." [GOC:dos]
synonym: "secretory vesicle membrane" BROAD []
is_a: GO:0030658 ! transport vesicle membrane
intersection_of: GO:0016020 ! membrane
intersection_of: bounding_layer_of GO:0070382 ! exocytic vesicle
relationship: bounding_layer_of GO:0070382 ! exocytic vesicle
relationship: part_of GO:0070382 ! exocytic vesicle

[Term]
id: GO:0099503
name: secretory vesicle
namespace: cellular_component
def: "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." [GOC:dos]
subset: goslim_drosophila
is_a: GO:0031410 ! cytoplasmic vesicle
intersection_of: GO:0031982 ! vesicle
intersection_of: capable_of GO:0099500 ! vesicle fusion to plasma membrane
relationship: capable_of GO:0099500 ! vesicle fusion to plasma membrane

[Term]
id: GO:0099512
name: supramolecular fiber
namespace: cellular_component
alt_id: GO:0043205
def: "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:dos]
synonym: "fibril" RELATED []
is_a: GO:0099081 ! supramolecular polymer
intersection_of: GO:0099080 ! supramolecular complex
intersection_of: has_characteristic PATO:0002309 ! fiber shaped
intersection_of: has_characteristic PATO:0015006 ! polymeric
relationship: has_characteristic PATO:0002309 ! fiber shaped

[Term]
id: GO:0099513
name: polymeric cytoskeletal fiber
namespace: cellular_component
def: "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." [GOC:dos]
is_a: GO:0099512 ! supramolecular fiber
intersection_of: GO:0099512 ! supramolecular fiber
intersection_of: has_characteristic PATO:0015006 ! polymeric
intersection_of: part_of GO:0005856 ! cytoskeleton
relationship: part_of GO:0005856 ! cytoskeleton

[Term]
id: GO:0099515
name: actin filament-based transport
namespace: biological_process
def: "The transport of organelles or other particles from one location in the cell to another along actin filaments." [GOC:dos, GOC:dph, GOC:mah, GOC:tb]
is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport
intersection_of: GO:0046907 ! intracellular transport
intersection_of: results_in_transport_along GO:0005884 ! actin filament
relationship: results_in_transport_along GO:0005884 ! actin filament
created_by: tb
creation_date: 2009-05-27T10:56:08Z

[Term]
id: GO:0099518
name: vesicle cytoskeletal trafficking
namespace: biological_process
def: "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins." [GOC:ecd, GOC:rl]
synonym: "cytoskeletal fiber-based vesicle localization" EXACT [GOC:rl]
synonym: "vesicle cytoskeletal transport" EXACT []
is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport
is_a: GO:0051650 ! establishment of vesicle localization
intersection_of: GO:0046907 ! intracellular transport
intersection_of: has_primary_input GO:0031982 ! vesicle
intersection_of: results_in_transport_along GO:0099513 ! polymeric cytoskeletal fiber

[Term]
id: GO:0099531
name: presynaptic process involved in chemical synaptic transmission
namespace: biological_process
def: "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission." [GOC:dos]
subset: gocheck_do_not_annotate
subset: goslim_synapse
is_a: GO:0050877 ! nervous system process
intersection_of: GO:0050877 ! nervous system process
intersection_of: occurs_in GO:0098793 ! presynapse
intersection_of: part_of GO:0007268 ! chemical synaptic transmission
relationship: occurs_in GO:0098793 ! presynapse
relationship: part_of GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099536
name: synaptic signaling
namespace: biological_process
def: "Cell-cell signaling to, from or within a synapse." [GOC:dos]
subset: goslim_drosophila
subset: goslim_synapse
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: occurs_in GO:0045202 ! synapse
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: occurs_in GO:0045202 ! synapse
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa

[Term]
id: GO:0099537
name: trans-synaptic signaling
namespace: biological_process
def: "Cell-cell signaling in either direction across the synaptic cleft." [GOC:dos]
subset: goslim_synapse
is_a: GO:0099536 ! synaptic signaling

[Term]
id: GO:0099538
name: synaptic signaling via neuropeptide
namespace: biological_process
def: "Cell-cell signaling to or from a synapse, mediated by a peptide." [GOC:dos]
subset: goslim_synapse
is_a: GO:0099536 ! synaptic signaling
intersection_of: GO:0099536 ! synaptic signaling
intersection_of: process_has_causal_agent CHEBI:16670 ! peptide
relationship: process_has_causal_agent CHEBI:16670 ! peptide

[Term]
id: GO:0099540
name: trans-synaptic signaling by neuropeptide
namespace: biological_process
def: "Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft." [GOC:dos]
subset: goslim_synapse
is_a: GO:0099537 ! trans-synaptic signaling
is_a: GO:0099538 ! synaptic signaling via neuropeptide
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: process_has_causal_agent CHEBI:16670 ! peptide

[Term]
id: GO:0099541
name: trans-synaptic signaling by lipid
namespace: biological_process
def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid." [GOC:dos]
subset: goslim_synapse
is_a: GO:0099537 ! trans-synaptic signaling
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: process_has_causal_agent CHEBI:18059 ! lipid
relationship: process_has_causal_agent CHEBI:18059 ! lipid

[Term]
id: GO:0099546
name: protein catabolic process, modulating synaptic transmission
namespace: biological_process
def: "Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission." [GOC:dos, PMID:23083742]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0140246 ! protein catabolic process at synapse
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:36080 ! protein
intersection_of: occurs_in GO:0045202 ! synapse
intersection_of: regulates GO:0007268 ! chemical synaptic transmission
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099547
name: regulation of translation at synapse, modulating synaptic transmission
namespace: biological_process
def: "Any process that modulates synaptic transmission by regulating translation occurring at the synapse." [GOC:dos]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0050804 ! modulation of chemical synaptic transmission
is_a: GO:0140243 ! regulation of translation at synapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: occurs_in GO:0045202 ! synapse
intersection_of: regulates GO:0006412 ! translation
intersection_of: regulates GO:0007268 ! chemical synaptic transmission
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa

[Term]
id: GO:0099550
name: trans-synaptic signaling, modulating synaptic transmission
namespace: biological_process
def: "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." [GOC:dos]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0050804 ! modulation of chemical synaptic transmission
is_a: GO:0099537 ! trans-synaptic signaling
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099551
name: trans-synaptic signaling by neuropeptide, modulating synaptic transmission
namespace: biological_process
def: "Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide
is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: process_has_causal_agent CHEBI:16670 ! peptide
intersection_of: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099552
name: trans-synaptic signaling by lipid, modulating synaptic transmission
namespace: biological_process
def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos, PMID:21531987]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0099541 ! trans-synaptic signaling by lipid
is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission
intersection_of: GO:0099537 ! trans-synaptic signaling
intersection_of: process_has_causal_agent CHEBI:18059 ! lipid
intersection_of: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099568
name: cytoplasmic region
namespace: cellular_component
def: "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm." [GOC:dos]
subset: gocheck_do_not_annotate
is_a: GO:0005737 ! cytoplasm
intersection_of: GO:0005737 ! cytoplasm
intersection_of: part_of GO:0005737 ! cytoplasm
relationship: part_of GO:0005737 ! cytoplasm

[Term]
id: GO:0099569
name: presynaptic cytoskeleton
namespace: cellular_component
def: "The portion of the cytoskeleton contained within the presynapse." [GOC:dos]
subset: goslim_synapse
is_a: GO:0005856 ! cytoskeleton
intersection_of: GO:0005856 ! cytoskeleton
intersection_of: part_of GO:0098793 ! presynapse
relationship: part_of GO:0098793 ! presynapse

[Term]
id: GO:0099571
name: postsynaptic cytoskeleton
namespace: cellular_component
def: "The portion of the cytoskeleton contained within the postsynapse." [GOC:dos, PMID:19889835]
subset: goslim_synapse
is_a: GO:0005856 ! cytoskeleton
intersection_of: GO:0005856 ! cytoskeleton
intersection_of: part_of GO:0098794 ! postsynapse
relationship: part_of GO:0098794 ! postsynapse

[Term]
id: GO:0099574
name: regulation of protein catabolic process at synapse, modulating synaptic transmission
namespace: biological_process
def: "Any process that modulates synaptic transmission by regulating protein degradation at the synapse." [GOC:dos]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0050804 ! modulation of chemical synaptic transmission
is_a: GO:0140250 ! regulation protein catabolic process at synapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: has_primary_input CHEBI:36080 ! protein
intersection_of: occurs_in GO:0045202 ! synapse
intersection_of: regulates GO:0007268 ! chemical synaptic transmission
intersection_of: regulates GO:0009056 ! catabolic process
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa

[Term]
id: GO:0099575
name: regulation of protein catabolic process at presynapse, modulating synaptic transmission
namespace: biological_process
def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse." [GOC:dos]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0042176 ! regulation of protein catabolic process
is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission
intersection_of: GO:0042176 ! regulation of protein catabolic process
intersection_of: occurs_in GO:0098793 ! presynapse
intersection_of: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099576
name: regulation of protein catabolic process at postsynapse, modulating synaptic transmission
namespace: biological_process
def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse." [GOC:dos]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0042176 ! regulation of protein catabolic process
is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission
intersection_of: GO:0042176 ! regulation of protein catabolic process
intersection_of: occurs_in GO:0098794 ! postsynapse
intersection_of: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099577
name: regulation of translation at presynapse, modulating synaptic transmission
namespace: biological_process
def: "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse." [GOC:dos]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission
is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission
is_a: GO:0140244 ! regulation of translation at presynapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: occurs_in GO:0098793 ! presynapse
intersection_of: regulates GO:0006412 ! translation
intersection_of: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099578
name: regulation of translation at postsynapse, modulating synaptic transmission
namespace: biological_process
def: "Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse." [GOC:dos]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission
is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission
is_a: GO:0140245 ! regulation of translation at postsynapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: occurs_in GO:0098794 ! postsynapse
intersection_of: regulates GO:0006412 ! translation
intersection_of: regulates GO:0007268 ! chemical synaptic transmission

[Term]
id: GO:0099632
name: protein transport within plasma membrane
namespace: biological_process
def: "A process in which protein is transported from one region of the plasma membrane to another." [GOC:dos]
is_a: GO:0032594 ! protein transport within lipid bilayer
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input PR:000000001 ! protein
intersection_of: occurs_in GO:0005886 ! plasma membrane
relationship: occurs_in GO:0005886 ! plasma membrane

[Term]
id: GO:0099640
name: axo-dendritic protein transport
namespace: biological_process
def: "The directed movement of proteins along microtubules in neuron projections." [ISBN:0815316194]
subset: goslim_synapse
synonym: "axonal protein transport" NARROW []
is_a: GO:0008088 ! axo-dendritic transport
is_a: GO:0098840 ! protein transport along microtubule
intersection_of: GO:0046907 ! intracellular transport
intersection_of: has_primary_input PR:000000001 ! protein
intersection_of: occurs_in GO:0043005 ! neuron projection
intersection_of: results_in_transport_along GO:0005874 ! microtubule

[Term]
id: GO:0099643
name: signal release from synapse
namespace: biological_process
def: "Any signal release from a synapse." [GOC:dos]
subset: goslim_synapse
is_a: GO:0023061 ! signal release
intersection_of: GO:0023061 ! signal release
intersection_of: occurs_in GO:0045202 ! synapse
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: occurs_in GO:0045202 ! synapse
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of GO:0099536 ! synaptic signaling

[Term]
id: GO:0099738
name: cell cortex region
namespace: cellular_component
def: "The complete extent of cell cortex that underlies some some region of the plasma membrane." [GOC:dos]
subset: gocheck_do_not_annotate
synonym: "perimembrane region" EXACT []
is_a: GO:0005938 ! cell cortex
is_a: GO:0099568 ! cytoplasmic region
intersection_of: GO:0005938 ! cell cortex
intersection_of: part_of GO:0005938 ! cell cortex
relationship: part_of GO:0005938 ! cell cortex

[Term]
id: GO:0100001
name: regulation of skeletal muscle contraction by action potential
namespace: biological_process
def: "Any action potential process that regulates skeletal muscle contraction." [GOC:cjm, GOC:obol]
is_a: GO:0001508 ! action potential
intersection_of: GO:0001508 ! action potential
intersection_of: regulates GO:0003009 ! skeletal muscle contraction
relationship: regulates GO:0003009 ! skeletal muscle contraction
created_by: cjm
creation_date: 2015-04-02T04:13:19Z

[Term]
id: GO:0101023
name: vascular endothelial cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:23201774]
is_a: GO:0001935 ! endothelial cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000071 ! blood vessel endothelial cell
relationship: acts_on_population_of CL:0000071 ! blood vessel endothelial cell

[Term]
id: GO:0101024
name: mitotic nuclear membrane organization
namespace: biological_process
def: "A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis." [GOC:vw, PMID:15147872]
comment: This process only occurs in organisms which undergo 'closed mitosis' without nuclear breakdown.
synonym: "nuclear membrane organization involved in mitotic nuclear division" EXACT []
is_a: GO:0071763 ! nuclear membrane organization
is_a: GO:1903047 ! mitotic cell cycle process
intersection_of: GO:0071763 ! nuclear membrane organization
intersection_of: part_of GO:0140014 ! mitotic nuclear division
relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota
relationship: part_of GO:0140014 ! mitotic nuclear division
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19949" xsd:anyURI

[Term]
id: GO:0101025
name: nuclear membrane biogenesis
namespace: biological_process
def: "The process in which a nuclear membrane is synthesized, aggregates, and bonds together." [GOC:vw]
is_a: GO:0044091 ! membrane biogenesis
intersection_of: GO:0044085 ! cellular component biogenesis
intersection_of: has_primary_output GO:0031965 ! nuclear membrane
relationship: has_primary_output GO:0031965 ! nuclear membrane
relationship: part_of GO:0071763 ! nuclear membrane organization

[Term]
id: GO:0106027
name: neuron projection organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite." [GOC:aruk, GOC:bc, PMID:11585923]
is_a: GO:0120036 ! plasma membrane bounded cell projection organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0043005 ! neuron projection
relationship: results_in_organization_of GO:0043005 ! neuron projection
created_by: hjd
creation_date: 2017-06-23T18:30:18Z

[Term]
id: GO:0106214
name: regulation of vesicle fusion with Golgi apparatus
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667]
is_a: GO:0031338 ! regulation of vesicle fusion
is_a: GO:1903358 ! regulation of Golgi organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048280 ! vesicle fusion with Golgi apparatus
relationship: regulates GO:0048280 ! vesicle fusion with Golgi apparatus
created_by: hjd
creation_date: 2019-06-27T15:12:22Z

[Term]
id: GO:0106215
name: negative regulation of vesicle fusion with Golgi apparatus
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus." [GOC:se, PMID:26195667]
is_a: GO:0031339 ! negative regulation of vesicle fusion
is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus
relationship: negatively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus
created_by: hjd
creation_date: 2019-06-27T15:17:17Z

[Term]
id: GO:0106216
name: positive regulation of vesicle fusion with Golgi apparatus
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667]
is_a: GO:0031340 ! positive regulation of vesicle fusion
is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus
relationship: positively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus
created_by: hjd
creation_date: 2019-06-27T15:20:59Z

[Term]
id: GO:0110011
name: regulation of basement membrane organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane." [GOC:ha, PMID:27404358]
is_a: GO:1903053 ! regulation of extracellular matrix organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0071711 ! basement membrane organization
relationship: regulates GO:0071711 ! basement membrane organization
created_by: kmv

[Term]
id: GO:0110020
name: regulation of actomyosin structure organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin." [GOC:lf, PMID:22790195]
is_a: GO:0032956 ! regulation of actin cytoskeleton organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0031032 ! actomyosin structure organization
relationship: regulates GO:0031032 ! actomyosin structure organization
created_by: kmv
creation_date: 2017-06-20T19:28:58Z

[Term]
id: GO:0110021
name: cardiac muscle myoblast proliferation
namespace: biological_process
def: "The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644]
is_a: GO:0051450 ! myoblast proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000513 ! cardiac muscle myoblast
relationship: acts_on_population_of CL:0000513 ! cardiac muscle myoblast
created_by: kmv
creation_date: 2017-06-29T14:35:24Z

[Term]
id: GO:0110022
name: regulation of cardiac muscle myoblast proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644]
is_a: GO:2000291 ! regulation of myoblast proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0110021 ! cardiac muscle myoblast proliferation
relationship: regulates GO:0110021 ! cardiac muscle myoblast proliferation
created_by: kmv
creation_date: 2017-06-29T15:11:47Z

[Term]
id: GO:0110023
name: negative regulation of cardiac muscle myoblast proliferation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644]
is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation
is_a: GO:2000818 ! negative regulation of myoblast proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0110021 ! cardiac muscle myoblast proliferation
relationship: negatively_regulates GO:0110021 ! cardiac muscle myoblast proliferation
created_by: kmv
creation_date: 2017-06-29T15:18:30Z

[Term]
id: GO:0110024
name: positive regulation of cardiac muscle myoblast proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644]
is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation
is_a: GO:2000288 ! positive regulation of myoblast proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0110021 ! cardiac muscle myoblast proliferation
relationship: positively_regulates GO:0110021 ! cardiac muscle myoblast proliferation
created_by: kmv
creation_date: 2017-06-29T15:24:16Z

[Term]
id: GO:0110053
name: regulation of actin filament organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of actin filament organization." [GOC:kmv]
is_a: GO:0032956 ! regulation of actin cytoskeleton organization
is_a: GO:1902903 ! regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007015 ! actin filament organization
relationship: regulates GO:0007015 ! actin filament organization
created_by: kmv
creation_date: 2017-09-20T19:52:57Z

[Term]
id: GO:0110057
name: regulation of blood vessel endothelial cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816]
is_a: GO:0045601 ! regulation of endothelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060837 ! blood vessel endothelial cell differentiation
relationship: regulates GO:0060837 ! blood vessel endothelial cell differentiation
created_by: kmv
creation_date: 2017-10-23T14:32:09Z

[Term]
id: GO:0110058
name: positive regulation of blood vessel endothelial cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816]
is_a: GO:0045603 ! positive regulation of endothelial cell differentiation
is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060837 ! blood vessel endothelial cell differentiation
relationship: positively_regulates GO:0060837 ! blood vessel endothelial cell differentiation
created_by: kmv
creation_date: 2017-10-23T14:38:19Z

[Term]
id: GO:0110059
name: negative regulation of blood vessel endothelial cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816]
is_a: GO:0045602 ! negative regulation of endothelial cell differentiation
is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060837 ! blood vessel endothelial cell differentiation
relationship: negatively_regulates GO:0060837 ! blood vessel endothelial cell differentiation
created_by: kmv
creation_date: 2017-10-23T14:47:29Z

[Term]
id: GO:0110077
name: vesicle-mediated intercellular transport
namespace: biological_process
def: "A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane." [GOC:sp, PMID:29328915, PMID:29328916]
is_a: GO:0010496 ! intercellular transport
is_a: GO:0016192 ! vesicle-mediated transport
intersection_of: GO:0010496 ! intercellular transport
intersection_of: process_has_causal_agent GO:1903561 ! extracellular vesicle
relationship: process_has_causal_agent GO:1903561 ! extracellular vesicle
created_by: kmv
creation_date: 2018-01-29T14:46:52Z

[Term]
id: GO:0110079
name: regulation of placenta blood vessel development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453]
is_a: GO:1901342 ! regulation of vasculature development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060674 ! placenta blood vessel development
relationship: regulates GO:0060674 ! placenta blood vessel development
created_by: kmv
creation_date: 2018-02-01T14:49:12Z

[Term]
id: GO:0110080
name: positive regulation of placenta blood vessel development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0110079 ! regulation of placenta blood vessel development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060674 ! placenta blood vessel development
relationship: positively_regulates GO:0060674 ! placenta blood vessel development
created_by: kmv
creation_date: 2018-02-01T14:55:30Z

[Term]
id: GO:0110081
name: negative regulation of placenta blood vessel development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0110079 ! regulation of placenta blood vessel development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060674 ! placenta blood vessel development
relationship: negatively_regulates GO:0060674 ! placenta blood vessel development
created_by: kmv
creation_date: 2018-02-01T15:01:11Z

[Term]
id: GO:0110110
name: positive regulation of animal organ morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:2000027 ! regulation of animal organ morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009887 ! animal organ morphogenesis
relationship: positively_regulates GO:0009887 ! animal organ morphogenesis
created_by: kmv
creation_date: 2018-07-05T14:10:14Z

[Term]
id: GO:0110111
name: negative regulation of animal organ morphogenesis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:2000027 ! regulation of animal organ morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009887 ! animal organ morphogenesis
relationship: negatively_regulates GO:0009887 ! animal organ morphogenesis
created_by: kmv
creation_date: 2018-07-05T14:25:21Z

[Term]
id: GO:0110112
name: regulation of lipid transporter activity
namespace: biological_process
def: "Any process that modulates the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390]
subset: gocheck_do_not_annotate
is_a: GO:0032368 ! regulation of lipid transport
is_a: GO:0032409 ! regulation of transporter activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0005319 ! lipid transporter activity
relationship: regulates GO:0005319 ! lipid transporter activity
created_by: kmv
creation_date: 2018-07-06T18:53:55Z

[Term]
id: GO:0110113
name: positive regulation of lipid transporter activity
namespace: biological_process
def: "Any process that increases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390]
subset: gocheck_do_not_annotate
is_a: GO:0032370 ! positive regulation of lipid transport
is_a: GO:0032411 ! positive regulation of transporter activity
is_a: GO:0110112 ! regulation of lipid transporter activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0005319 ! lipid transporter activity
relationship: positively_regulates GO:0005319 ! lipid transporter activity
created_by: kmv
creation_date: 2018-07-06T19:14:13Z

[Term]
id: GO:0110114
name: negative regulation of lipid transporter activity
namespace: biological_process
def: "Any process that decreases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390]
subset: gocheck_do_not_annotate
is_a: GO:0032369 ! negative regulation of lipid transport
is_a: GO:0032410 ! negative regulation of transporter activity
is_a: GO:0110112 ! regulation of lipid transporter activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0005319 ! lipid transporter activity
relationship: negatively_regulates GO:0005319 ! lipid transporter activity
created_by: kmv
creation_date: 2018-07-06T19:21:44Z

[Term]
id: GO:0110116
name: regulation of compound eye photoreceptor cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567]
is_a: GO:0046532 ! regulation of photoreceptor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001751 ! compound eye photoreceptor cell differentiation
relationship: regulates GO:0001751 ! compound eye photoreceptor cell differentiation
created_by: kmv
creation_date: 2018-07-16T18:08:49Z

[Term]
id: GO:0110117
name: positive regulation of compound eye photoreceptor cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567]
is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation
is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation
relationship: positively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation
created_by: kmv
creation_date: 2018-07-16T18:13:28Z

[Term]
id: GO:0110118
name: negative regulation of compound eye photoreceptor cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567]
is_a: GO:0046533 ! negative regulation of photoreceptor cell differentiation
is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation
relationship: negatively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation
created_by: kmv
creation_date: 2018-07-16T18:15:52Z

[Term]
id: GO:0110122
name: myotube cell migration
namespace: biological_process
def: "The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse." [GOC:ha, PMID:29122742]
is_a: GO:0014812 ! muscle cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0002372 ! myotube
relationship: results_in_movement_of CL:0002372 ! myotube
created_by: kmv
creation_date: 2018-08-22T20:58:09Z

[Term]
id: GO:0110123
name: regulation of myotube cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742]
is_a: GO:0030334 ! regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0110122 ! myotube cell migration
relationship: regulates GO:0110122 ! myotube cell migration
created_by: kmv
creation_date: 2018-08-22T21:06:53Z

[Term]
id: GO:0110124
name: positive regulation of myotube cell migration
namespace: biological_process
def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742]
is_a: GO:0030335 ! positive regulation of cell migration
is_a: GO:0110123 ! regulation of myotube cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0110122 ! myotube cell migration
relationship: positively_regulates GO:0110122 ! myotube cell migration
created_by: kmv
creation_date: 2018-08-22T21:09:38Z

[Term]
id: GO:0110125
name: negative regulation of myotube cell migration
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742]
is_a: GO:0030336 ! negative regulation of cell migration
is_a: GO:0110123 ! regulation of myotube cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0110122 ! myotube cell migration
relationship: negatively_regulates GO:0110122 ! myotube cell migration
created_by: kmv
creation_date: 2018-08-22T21:12:47Z

[Term]
id: GO:0110165
name: cellular anatomical entity
namespace: cellular_component
def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [GOC:kmv]
subset: gocheck_do_not_annotate
subset: goslim_pir
is_a: CARO:0000000 ! anatomical entity
is_a: GO:0005575 ! cellular_component
is_a: UBERON:0000061 ! anatomical structure
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI
created_by: kmv
creation_date: 2019-08-12T18:01:37Z

[Term]
id: GO:0120025
name: plasma membrane bounded cell projection
namespace: cellular_component
def: "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc]
is_a: GO:0042995 ! cell projection
intersection_of: GO:0042995 ! cell projection
intersection_of: has_part GO:0098590 ! plasma membrane region
relationship: has_part GO:0098590 ! plasma membrane region
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13193" xsd:anyURI
created_by: krc
creation_date: 2017-03-21T17:26:07Z

[Term]
id: GO:0120031
name: plasma membrane bounded cell projection assembly
namespace: biological_process
def: "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc]
synonym: "eupodium" NARROW [GOC:krc, GOC:rjd, PMID:10328951, PMID:9096956]
is_a: GO:0030031 ! cell projection assembly
is_a: GO:0120036 ! plasma membrane bounded cell projection organization
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0120025 ! plasma membrane bounded cell projection
relationship: results_in_assembly_of GO:0120025 ! plasma membrane bounded cell projection
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI
created_by: krc
creation_date: 2017-04-24T23:56:08Z

[Term]
id: GO:0120032
name: regulation of plasma membrane bounded cell projection assembly
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly." [GOC:krc]
is_a: GO:0060491 ! regulation of cell projection assembly
is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0120031 ! plasma membrane bounded cell projection assembly
relationship: regulates GO:0120031 ! plasma membrane bounded cell projection assembly
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI
created_by: krc
creation_date: 2017-04-26T04:27:04Z

[Term]
id: GO:0120033
name: negative regulation of plasma membrane bounded cell projection assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc]
is_a: GO:0031345 ! negative regulation of cell projection organization
is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly
relationship: negatively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI
created_by: krc
creation_date: 2017-04-26T04:34:31Z

[Term]
id: GO:0120034
name: positive regulation of plasma membrane bounded cell projection assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc]
is_a: GO:0031346 ! positive regulation of cell projection organization
is_a: GO:0044089 ! positive regulation of cellular component biogenesis
is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly
relationship: positively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI
created_by: krc
creation_date: 2017-04-26T04:34:45Z

[Term]
id: GO:0120035
name: regulation of plasma membrane bounded cell projection organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." [GOC:krc]
is_a: GO:0031344 ! regulation of cell projection organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0120036 ! plasma membrane bounded cell projection organization
relationship: regulates GO:0120036 ! plasma membrane bounded cell projection organization
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI
created_by: krc
creation_date: 2017-04-26T16:02:06Z

[Term]
id: GO:0120036
name: plasma membrane bounded cell projection organization
namespace: biological_process
def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." [GOC:krc]
is_a: GO:0030030 ! cell projection organization
intersection_of: GO:0016043 ! cellular component organization
intersection_of: results_in_organization_of GO:0120025 ! plasma membrane bounded cell projection
relationship: results_in_organization_of GO:0120025 ! plasma membrane bounded cell projection
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI
created_by: krc
creation_date: 2017-04-26T16:07:02Z

[Term]
id: GO:0120039
name: plasma membrane bounded cell projection morphogenesis
namespace: biological_process
def: "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized." [GOC:krc]
is_a: GO:0048858 ! cell projection morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of GO:0120025 ! plasma membrane bounded cell projection
relationship: results_in_morphogenesis_of GO:0120025 ! plasma membrane bounded cell projection
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI
created_by: krc
creation_date: 2017-04-28T23:39:37Z

[Term]
id: GO:0120111
name: neuron projection cytoplasm
namespace: cellular_component
def: "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." [GOC:ha]
is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm
intersection_of: GO:0005737 ! cytoplasm
intersection_of: part_of GO:0043005 ! neuron projection
relationship: part_of GO:0043005 ! neuron projection
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14472" xsd:anyURI
created_by: krc
creation_date: 2017-11-01T18:58:12Z

[Term]
id: GO:0120158
name: positive regulation of collagen catabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:dph, GOC:tb]
synonym: "activation of collagen catabolic process" NARROW [GOC:dph, GOC:tb]
synonym: "positive regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb]
synonym: "positive regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb]
synonym: "positive regulation of collagen degradation" EXACT [GOC:dph, GOC:tb]
synonym: "up regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb]
synonym: "up-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb]
synonym: "upregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb]
is_a: GO:0009896 ! positive regulation of catabolic process
is_a: GO:0010710 ! regulation of collagen catabolic process
is_a: GO:0010714 ! positive regulation of collagen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030574 ! collagen catabolic process
relationship: positively_regulates GO:0030574 ! collagen catabolic process
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15720" xsd:anyURI
created_by: krc
creation_date: 2018-05-11T16:31:42Z

[Term]
id: GO:0120178
name: steroid hormone biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:krc, GOC:nln]
is_a: GO:0006694 ! steroid biosynthetic process
intersection_of: GO:0006694 ! steroid biosynthetic process
intersection_of: has_primary_output CHEBI:26764 ! steroid hormone
relationship: has_primary_output CHEBI:26764 ! steroid hormone
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16000" xsd:anyURI
created_by: krc
creation_date: 2019-05-20T22:34:00Z

[Term]
id: GO:0120186
name: negative regulation of protein localization to chromatin
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453]
synonym: "negative regulation of protein localisation to chromatin" EXACT [GOC:krc]
is_a: GO:1903828 ! negative regulation of protein localization
is_a: GO:1905634 ! regulation of protein localization to chromatin
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0071168 ! protein localization to chromatin
relationship: negatively_regulates GO:0071168 ! protein localization to chromatin
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16012" xsd:anyURI
created_by: krc
creation_date: 2018-07-14T00:19:32Z

[Term]
id: GO:0120187
name: positive regulation of protein localization to chromatin
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453]
synonym: "positive regulation of protein localisation to chromatin" EXACT [GOC:krc]
is_a: GO:1903829 ! positive regulation of protein localization
is_a: GO:1905634 ! regulation of protein localization to chromatin
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0071168 ! protein localization to chromatin
relationship: positively_regulates GO:0071168 ! protein localization to chromatin
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16012" xsd:anyURI
created_by: krc
creation_date: 2018-07-14T00:21:28Z

[Term]
id: GO:0120188
name: regulation of bile acid secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443]
is_a: GO:0051046 ! regulation of secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032782 ! bile acid secretion
relationship: regulates GO:0032782 ! bile acid secretion
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI
created_by: krc
creation_date: 2018-07-16T22:28:58Z

[Term]
id: GO:0120189
name: positive regulation of bile acid secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443]
is_a: GO:0051047 ! positive regulation of secretion
is_a: GO:0120188 ! regulation of bile acid secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032782 ! bile acid secretion
relationship: positively_regulates GO:0032782 ! bile acid secretion
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI
created_by: krc
creation_date: 2018-07-16T22:36:17Z

[Term]
id: GO:0120190
name: negative regulation of bile acid secretion
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443]
is_a: GO:0051048 ! negative regulation of secretion
is_a: GO:0120188 ! regulation of bile acid secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032782 ! bile acid secretion
relationship: negatively_regulates GO:0032782 ! bile acid secretion
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI
created_by: krc
creation_date: 2018-07-16T22:38:34Z

[Term]
id: GO:0120222
name: regulation of blastocyst development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of blastocyst development." [GOC:krc, PMID:29593216]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001824 ! blastocyst development
relationship: regulates GO:0001824 ! blastocyst development
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18871" xsd:anyURI
created_by: krc
creation_date: 2020-02-17T19:59:20Z

[Term]
id: GO:0120229
name: protein localization to motile cilium
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a motile cilium." [GOC:krc, PMID:27486780]
synonym: "protein localization to nonmotile primary cilium" RELATED []
is_a: GO:0061512 ! protein localization to cilium
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0031514 ! motile cilium
relationship: has_target_end_location GO:0031514 ! motile cilium
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19588" xsd:anyURI
created_by: krc
creation_date: 2020-06-05T23:43:04Z

[Term]
id: GO:0120305
name: regulation of pigmentation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism." [GOC:krc]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0043473 ! pigmentation
relationship: regulates GO:0043473 ! pigmentation
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20524" xsd:anyURI
created_by: krc
creation_date: 2021-02-09T19:37:35Z

[Term]
id: GO:0120316
name: sperm flagellum assembly
namespace: biological_process
def: "The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium)." [GOC:krc, PMID:32791035]
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:0044458 ! motile cilium assembly
intersection_of: GO:0044458 ! motile cilium assembly
intersection_of: occurs_in CL:0000019 ! sperm
relationship: occurs_in CL:0000019 ! sperm
relationship: part_of GO:0007286 ! spermatid development
relationship: part_of GO:0030317 ! flagellated sperm motility
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21361" xsd:anyURI
created_by: krc
creation_date: 2021-04-29T01:27:27Z

[Term]
id: GO:0120331
name: endothelial tube formation
namespace: biological_process
def: "The developmental process pertaining to the initial formation of an endothelial tube." [GOC:sl, PMID:23239824]
is_a: GO:0072175 ! epithelial tube formation
intersection_of: GO:0035148 ! tube formation
intersection_of: results_in_formation_of_anatomical_entity UBERON:0003915 ! endothelial tube
relationship: part_of GO:0061154 ! endothelial tube morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0003915 ! endothelial tube
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22302" xsd:anyURI
created_by: krc
creation_date: 2022-05-25T16:17:59Z

[Term]
id: GO:0140013
name: meiotic nuclear division
namespace: biological_process
def: "One of the two nuclear divisions that occur as part of the meiotic cell cycle." [PMID:9334324]
subset: goslim_generic
synonym: "meiosis" EXACT []
is_a: GO:0000280 ! nuclear division
is_a: GO:1903046 ! meiotic cell cycle process
intersection_of: GO:0000280 ! nuclear division
intersection_of: part_of GO:0051321 ! meiotic cell cycle
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19910" xsd:anyURI
created_by: pg
creation_date: 2017-03-23T09:40:00Z

[Term]
id: GO:0140014
name: mitotic nuclear division
namespace: biological_process
def: "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." [ISBN:0198547684]
subset: goslim_chembl
subset: goslim_generic
synonym: "mitosis" EXACT []
is_a: GO:0000280 ! nuclear division
is_a: GO:1903047 ! mitotic cell cycle process
intersection_of: GO:0000280 ! nuclear division
intersection_of: part_of GO:0000278 ! mitotic cell cycle
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19910" xsd:anyURI
created_by: pg
creation_date: 2017-03-23T14:44:23Z

[Term]
id: GO:0140029
name: exocytic process
namespace: biological_process
def: "The cellular processes that contribute to exocytosis." [Wikipedia:Exocytosis]
subset: gocheck_do_not_annotate
is_a: GO:0009987 ! cellular process
intersection_of: GO:0009987 ! cellular process
intersection_of: part_of GO:0006887 ! exocytosis
relationship: part_of GO:0006887 ! exocytosis
created_by: pg
creation_date: 2017-05-15T13:20:45Z

[Term]
id: GO:0140056
name: organelle localization by membrane tethering
namespace: biological_process
def: "The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other." [PMID:27875684]
subset: goslim_pombe
is_a: GO:0022406 ! membrane docking
is_a: GO:0051640 ! organelle localization
created_by: pg
creation_date: 2017-06-27T09:58:51Z

[Term]
id: GO:0140096
name: catalytic activity, acting on a protein
namespace: molecular_function
def: "Catalytic activity that acts to modify a protein." [GOC:molecular_function_refactoring, GOC:pdt]
subset: goslim_generic
subset: goslim_prokaryote
is_a: GO:0003824 ! catalytic activity
intersection_of: GO:0003824 ! catalytic activity
intersection_of: has_primary_input PR:000000001 ! protein
relationship: has_primary_input PR:000000001 ! protein
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI
created_by: pg
creation_date: 2017-09-14T10:32:59Z

[Term]
id: GO:0140097
name: catalytic activity, acting on DNA
namespace: molecular_function
def: "Catalytic activity that acts to modify DNA." [GOC:molecular_function_refactoring, GOC:pdt]
subset: goslim_generic
subset: goslim_prokaryote
is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid
intersection_of: GO:0003824 ! catalytic activity
intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid
relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI
created_by: pg
creation_date: 2017-09-14T12:03:51Z

[Term]
id: GO:0140098
name: catalytic activity, acting on RNA
namespace: molecular_function
def: "Catalytic activity that acts to modify RNA, driven by ATP hydrolysis." [GOC:molecular_function_refactoring, GOC:pdt]
subset: goslim_generic
subset: goslim_prokaryote
is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid
intersection_of: GO:0003824 ! catalytic activity
intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid
relationship: has_primary_input CHEBI:33697 ! ribonucleic acid
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI
created_by: pg
creation_date: 2017-09-14T12:05:21Z

[Term]
id: GO:0140103
name: catalytic activity, acting on a glycoprotein
namespace: molecular_function
def: "Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein." [GOC:molecular_function_refactoring, GOC:pdt]
is_a: GO:0003824 ! catalytic activity
intersection_of: GO:0003824 ! catalytic activity
intersection_of: has_primary_input CHEBI:17089 ! glycoprotein
relationship: has_primary_input CHEBI:17089 ! glycoprotein
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI
created_by: pg
creation_date: 2017-09-15T19:27:54Z

[Term]
id: GO:0140112
name: extracellular vesicle biogenesis
namespace: biological_process
def: "The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content." [PMID:28736435]
synonym: "extracellular vesicle assembly" EXACT []
is_a: GO:0044085 ! cellular component biogenesis
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14256" xsd:anyURI
created_by: pg
creation_date: 2017-10-23T11:53:42Z

[Term]
id: GO:0140236
name: translation at presynapse
namespace: biological_process
def: "Translation that occurs at the presynapse." [PMID:27321671]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0140241 ! translation at synapse
intersection_of: GO:0006412 ! translation
intersection_of: occurs_in GO:0098793 ! presynapse
relationship: occurs_in GO:0098793 ! presynapse
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/216" xsd:anyURI
created_by: pg
creation_date: 2018-07-13T13:00:33Z

[Term]
id: GO:0140237
name: translation at presynapse, modulating chemical synaptic transmission
namespace: biological_process
def: "Translation that occurs at the presynapse, and that modulates chemical synaptic transmission." [PMID:27321671]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0140236 ! translation at presynapse
intersection_of: GO:0006412 ! translation
intersection_of: occurs_in GO:0098793 ! presynapse
intersection_of: regulates GO:0007268 ! chemical synaptic transmission
relationship: regulates GO:0007268 ! chemical synaptic transmission
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/216" xsd:anyURI
created_by: pg
creation_date: 2018-07-13T13:07:23Z

[Term]
id: GO:0140238
name: presynaptic endocytosis
namespace: biological_process
def: "A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [PMID:24719103]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0006897 ! endocytosis
is_a: GO:0051649 ! establishment of localization in cell
is_a: GO:0099003 ! vesicle-mediated transport in synapse
intersection_of: GO:0006897 ! endocytosis
intersection_of: occurs_in GO:0098793 ! presynapse
relationship: occurs_in GO:0098793 ! presynapse
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/230" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T07:33:55Z

[Term]
id: GO:0140239
name: postsynaptic endocytosis
namespace: biological_process
def: "A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [PMID:12839988]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0006897 ! endocytosis
is_a: GO:0051649 ! establishment of localization in cell
is_a: GO:0099003 ! vesicle-mediated transport in synapse
intersection_of: GO:0006897 ! endocytosis
intersection_of: occurs_in GO:0098794 ! postsynapse
relationship: occurs_in GO:0098794 ! postsynapse
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/230" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T07:38:27Z

[Term]
id: GO:0140241
name: translation at synapse
namespace: biological_process
def: "Translation that occurs at the synapse." [PMID:23083742]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0006412 ! translation
intersection_of: GO:0006412 ! translation
intersection_of: occurs_in GO:0045202 ! synapse
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: occurs_in GO:0045202 ! synapse
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T09:23:12Z

[Term]
id: GO:0140242
name: translation at postsynapse
namespace: biological_process
def: "Translation that occurs at the postsynapse." [PMID:20427644]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0140241 ! translation at synapse
intersection_of: GO:0006412 ! translation
intersection_of: occurs_in GO:0098794 ! postsynapse
relationship: occurs_in GO:0098794 ! postsynapse
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T09:26:27Z

[Term]
id: GO:0140243
name: regulation of translation at synapse
namespace: biological_process
def: "Any process that regulates translation occurring at the synapse." [PMID:20427644]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0006417 ! regulation of translation
intersection_of: GO:0065007 ! biological regulation
intersection_of: occurs_in GO:0045202 ! synapse
intersection_of: regulates GO:0006412 ! translation
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: occurs_in GO:0045202 ! synapse
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T09:38:26Z

[Term]
id: GO:0140244
name: regulation of translation at presynapse
namespace: biological_process
def: "Any process that regulates translation occurring at the presynapse." [PMID:20427644]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0140243 ! regulation of translation at synapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: occurs_in GO:0098793 ! presynapse
intersection_of: regulates GO:0006412 ! translation
relationship: occurs_in GO:0098793 ! presynapse
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T09:38:33Z

[Term]
id: GO:0140245
name: regulation of translation at postsynapse
namespace: biological_process
def: "Any process that regulates translation occurring at the postsynapse." [PMID:20427644]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0140243 ! regulation of translation at synapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: occurs_in GO:0098794 ! postsynapse
intersection_of: regulates GO:0006412 ! translation
relationship: occurs_in GO:0098794 ! postsynapse
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T09:38:54Z

[Term]
id: GO:0140246
name: protein catabolic process at synapse
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of a protein at a synapse." [PMID:17062563]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0009057 ! macromolecule catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:36080 ! protein
intersection_of: occurs_in GO:0045202 ! synapse
relationship: has_primary_input CHEBI:36080 ! protein
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: occurs_in GO:0045202 ! synapse
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T10:12:51Z

[Term]
id: GO:0140247
name: protein catabolic process at presynapse
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse." [PMID:27764673]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0140246 ! protein catabolic process at synapse
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:36080 ! protein
intersection_of: occurs_in GO:0098793 ! presynapse
relationship: occurs_in GO:0098793 ! presynapse
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T10:23:49Z

[Term]
id: GO:0140249
name: protein catabolic process at postsynapse
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse." [PMID:17062563]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0140246 ! protein catabolic process at synapse
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:36080 ! protein
intersection_of: occurs_in GO:0098794 ! postsynapse
relationship: occurs_in GO:0098794 ! postsynapse
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T10:25:04Z

[Term]
id: GO:0140250
name: regulation protein catabolic process at synapse
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse." [PMID:23083742]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0009894 ! regulation of catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: has_primary_input CHEBI:36080 ! protein
intersection_of: occurs_in GO:0045202 ! synapse
intersection_of: regulates GO:0009056 ! catabolic process
relationship: has_primary_input CHEBI:36080 ! protein
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: occurs_in GO:0045202 ! synapse
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T10:34:56Z

[Term]
id: GO:0140251
name: regulation protein catabolic process at presynapse
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse." [PMID:27764673]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0140250 ! regulation protein catabolic process at synapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: has_primary_input CHEBI:36080 ! protein
intersection_of: occurs_in GO:0098793 ! presynapse
intersection_of: regulates GO:0009056 ! catabolic process
relationship: occurs_in GO:0098793 ! presynapse
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T10:35:39Z

[Term]
id: GO:0140252
name: regulation protein catabolic process at postsynapse
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse." [PMID:17062563]
comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
subset: goslim_synapse
is_a: GO:0140250 ! regulation protein catabolic process at synapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: has_primary_input CHEBI:36080 ! protein
intersection_of: occurs_in GO:0098794 ! postsynapse
intersection_of: regulates GO:0009056 ! catabolic process
relationship: occurs_in GO:0098794 ! postsynapse
property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI
created_by: pg
creation_date: 2018-07-15T10:35:56Z

[Term]
id: GO:0140253
name: cell-cell fusion
namespace: biological_process
def: "A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium." [Wikipedia:Cell_fusion]
synonym: "cell cell fusion" EXACT []
synonym: "cell fusion" BROAD []
is_a: GO:0009987 ! cellular process
relationship: has_part GO:0045026 ! plasma membrane fusion
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15939" xsd:anyURI
created_by: pg
creation_date: 2018-08-13T18:38:18Z

[Term]
id: GO:0140318
name: protein transporter activity
namespace: molecular_function
def: "Directly binding to a specific protein and delivering it to a specific cellular location." [PMID:18706423]
comment: Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation.
synonym: "protein carrier activity" RELATED []
synonym: "protein transport chaperone" RELATED []
xref: Reactome:R-HSA-9662747 "iRHOM2 transports ADAM17 from ER to the Golgi-network"
xref: Reactome:R-HSA-9662818 "iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane"
is_a: GO:0005215 ! transporter activity
intersection_of: GO:0005215 ! transporter activity
intersection_of: has_primary_input PR:000000001 ! protein
relationship: has_primary_input PR:000000001 ! protein
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17073" xsd:anyURI
created_by: pg
creation_date: 2019-04-01T10:41:38Z

[Term]
id: GO:0140352
name: export from cell
namespace: biological_process
def: "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." [GOC:pg]
synonym: "efflux" BROAD []
is_a: GO:0006810 ! transport
is_a: GO:0009987 ! cellular process
intersection_of: GO:0006810 ! transport
intersection_of: has_target_end_location GO:0005576 ! extracellular region
intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure
relationship: has_target_end_location GO:0005576 ! extracellular region
relationship: has_target_start_location GO:0005622 ! intracellular anatomical structure
created_by: pg
creation_date: 2019-05-22T11:20:45Z

[Term]
id: GO:0140353
name: lipid export from cell
namespace: biological_process
def: "The directed movement of a lipid from a cell, into the extracellular region." [GOC:pg]
synonym: "lipid efflux" BROAD []
is_a: GO:0006869 ! lipid transport
is_a: GO:0140352 ! export from cell
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:18059 ! lipid
intersection_of: has_target_end_location GO:0005576 ! extracellular region
intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure
created_by: pg
creation_date: 2019-05-22T11:33:07Z

[Term]
id: GO:0140354
name: lipid import into cell
namespace: biological_process
def: "The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:pg]
synonym: "lipid uptake" BROAD []
is_a: GO:0006869 ! lipid transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:18059 ! lipid
intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure
intersection_of: has_target_start_location GO:0005576 ! extracellular region
relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure
relationship: has_target_start_location GO:0005576 ! extracellular region
created_by: pg
creation_date: 2019-05-22T11:38:15Z

[Term]
id: GO:0140513
name: nuclear protein-containing complex
namespace: cellular_component
def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus." [GOC:pg]
subset: gocheck_do_not_annotate
synonym: "nuclear complex" EXACT []
is_a: GO:0032991 ! protein-containing complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: part_of GO:0005634 ! nucleus
relationship: part_of GO:0005634 ! nucleus
created_by: pg
creation_date: 2020-09-09T05:12:38Z

[Term]
id: GO:0140572
name: vacuole fission
namespace: biological_process
def: "The division of a vacuole within a cell to form two or more separate vacuoles." [PMID:19643199]
is_a: GO:0048285 ! organelle fission
intersection_of: GO:0048285 ! organelle fission
intersection_of: results_in_fission_of GO:0005773 ! vacuole
relationship: results_in_fission_of GO:0005773 ! vacuole
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20639" xsd:anyURI
created_by: pg
creation_date: 2021-01-04T10:17:58Z

[Term]
id: GO:0140640
name: catalytic activity, acting on a nucleic acid
namespace: molecular_function
def: "Catalytic activity that acts to modify a nucleic acid." [GOC:pg]
is_a: GO:0003824 ! catalytic activity
intersection_of: GO:0003824 ! catalytic activity
intersection_of: has_primary_input CHEBI:33696 ! nucleic acid
relationship: has_primary_input CHEBI:33696 ! nucleic acid
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21402" xsd:anyURI
created_by: pg
creation_date: 2021-05-11T06:31:07Z

[Term]
id: GO:0140694
name: non-membrane-bounded organelle assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle." [PMID:28225081]
synonym: "non-membrane-bounded organelle formation" EXACT []
synonym: "non-membrane-enclosed organelle assembly" EXACT []
synonym: "non-membrane-enclosed organelle formation" EXACT []
is_a: GO:0070925 ! organelle assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0043228 ! non-membrane-bounded organelle
relationship: results_in_assembly_of GO:0043228 ! non-membrane-bounded organelle
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21939" xsd:anyURI
created_by: pg
creation_date: 2021-08-09T15:30:06Z

[Term]
id: GO:0140734
name: ammonium excretion
namespace: biological_process
def: "The elimination of ammonium ions from an excretory cell." [PMID:25740900]
synonym: "ammonia excretion" RELATED []
is_a: GO:0007588 ! excretion
intersection_of: GO:0007588 ! excretion
intersection_of: has_primary_input CHEBI:28938 ! ammonium
relationship: has_primary_input CHEBI:28938 ! ammonium
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI
created_by: pg
creation_date: 2021-11-24T17:55:51Z

[Term]
id: GO:0140961
name: cellular detoxification of metal ion
namespace: biological_process
def: "Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion." [PMID:26729300, PMID:33046888, PMID:34442707]
synonym: "cellular detoxification of metal cation" EXACT []
is_a: GO:0061687 ! detoxification of inorganic compound
is_a: GO:1990748 ! cellular detoxification
intersection_of: GO:1990748 ! cellular detoxification
intersection_of: has_primary_input CHEBI:25213 ! metal cation
relationship: has_primary_input CHEBI:25213 ! metal cation
created_by: pg
creation_date: 2022-12-07T15:35:18Z

[Term]
id: GO:0150052
name: regulation of postsynapse assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:aruk, GOC:bc, PMID:16394100, PMID:16672654, PMID:28185854]
subset: goslim_synapse
is_a: GO:0051963 ! regulation of synapse assembly
is_a: GO:0099175 ! regulation of postsynapse organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0099068 ! postsynapse assembly
relationship: regulates GO:0099068 ! postsynapse assembly
created_by: bc
creation_date: 2018-05-08T16:38:55Z

[Term]
id: GO:0150063
name: visual system development
namespace: biological_process
def: "The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways." [GOC:aruk, GOC:bc, GOC:krc, PMID:15004427, PMID:20647017, PMID:22632727]
synonym: "optic pathway development" RELATED []
synonym: "visual pathway development" RELATED []
is_a: GO:0048880 ! sensory system development
created_by: bc
creation_date: 2018-07-23T10:31:58Z

[Term]
id: GO:0150076
name: neuroinflammatory response
namespace: biological_process
def: "The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423]
synonym: "nerve tissue inflammatory response" EXACT []
synonym: "nervous tissue inflammatory response" EXACT []
synonym: "neural tissue inflammatory response" EXACT []
is_a: GO:0006954 ! inflammatory response
created_by: bc
creation_date: 2018-07-26T12:25:34Z

[Term]
id: GO:0150077
name: regulation of neuroinflammatory response
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423]
is_a: GO:0050727 ! regulation of inflammatory response
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0150076 ! neuroinflammatory response
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: regulates GO:0150076 ! neuroinflammatory response
created_by: bc
creation_date: 2018-07-26T12:32:18Z

[Term]
id: GO:0150078
name: positive regulation of neuroinflammatory response
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc]
is_a: GO:0050729 ! positive regulation of inflammatory response
is_a: GO:0150077 ! regulation of neuroinflammatory response
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0150076 ! neuroinflammatory response
relationship: positively_regulates GO:0150076 ! neuroinflammatory response
created_by: bc
creation_date: 2018-07-26T12:35:50Z

[Term]
id: GO:0150079
name: negative regulation of neuroinflammatory response
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:11099416, PMID:18164423]
is_a: GO:0050728 ! negative regulation of inflammatory response
is_a: GO:0150077 ! regulation of neuroinflammatory response
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0150076 ! neuroinflammatory response
relationship: negatively_regulates GO:0150076 ! neuroinflammatory response
created_by: bc
creation_date: 2018-07-26T12:38:08Z

[Term]
id: GO:0150098
name: glial cell-neuron signaling
namespace: biological_process
def: "Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum." [GOC:aruk, GOC:bc, PMID:14980203, PMID:16144764, PMID:16547515, PMID:18685038, PMID:27788368, PMID:9459440]
synonym: "glia-neuron signaling" EXACT []
synonym: "glia-neuron signalling" EXACT []
synonym: "glia-neurone signaling" EXACT []
synonym: "glia-neurone signalling" EXACT []
synonym: "glial cell- neuron signalling" EXACT []
synonym: "glial cell-neurone signalling" EXACT []
synonym: "glial cell-neurone singaling" EXACT []
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: has_end_location CL:0000540 ! neuron
intersection_of: has_start_location CL:0000125 ! glial cell
relationship: has_end_location CL:0000540 ! neuron
relationship: has_start_location CL:0000125 ! glial cell
created_by: bc
creation_date: 2018-12-17T12:28:09Z

[Term]
id: GO:0150099
name: neuron-glial cell signaling
namespace: biological_process
def: "Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine." [GOC:aruk, GOC:bc, PMID:10195197, PMID:10196584, PMID:10377338, PMID:10493741, PMID:11356870, PMID:11399439, PMID:15252819, PMID:27788368]
synonym: "neuron-glia signaling" EXACT []
synonym: "neuron-glia signalling" EXACT []
synonym: "neuron-glial cell signalling" EXACT []
synonym: "neurone-glia signaling" EXACT []
synonym: "neurone-glia signalling" EXACT []
synonym: "neurone-glial cell signaling" EXACT []
synonym: "neurone-glial cell signalling" EXACT []
is_a: GO:0007267 ! cell-cell signaling
intersection_of: GO:0007267 ! cell-cell signaling
intersection_of: has_end_location CL:0000125 ! glial cell
intersection_of: has_start_location CL:0000540 ! neuron
relationship: has_end_location CL:0000125 ! glial cell
relationship: has_start_location CL:0000540 ! neuron
created_by: bc
creation_date: 2018-12-17T12:30:12Z

[Term]
id: GO:0150105
name: protein localization to cell-cell junction
namespace: biological_process
def: "A process in which a protein is transported to, or maintained, in a location within a cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435]
is_a: GO:1902414 ! protein localization to cell junction
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005911 ! cell-cell junction
relationship: has_target_end_location GO:0005911 ! cell-cell junction
created_by: bc
creation_date: 2019-06-11T11:00:18Z

[Term]
id: GO:0150106
name: regulation of protein localization to cell-cell junction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435]
is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0150105 ! protein localization to cell-cell junction
relationship: regulates GO:0150105 ! protein localization to cell-cell junction
created_by: bc
creation_date: 2019-06-11T11:17:15Z

[Term]
id: GO:0150107
name: positive regulation of protein localization to cell-cell junction
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435]
is_a: GO:0150106 ! regulation of protein localization to cell-cell junction
is_a: GO:1903829 ! positive regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0150105 ! protein localization to cell-cell junction
relationship: positively_regulates GO:0150105 ! protein localization to cell-cell junction
created_by: bc
creation_date: 2019-06-11T11:23:58Z

[Term]
id: GO:0150111
name: regulation of transepithelial transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of transepithelial transport." [GOC:aruk, PMID:27593915]
is_a: GO:0051049 ! regulation of transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070633 ! transepithelial transport
relationship: regulates GO:0070633 ! transepithelial transport
created_by: bc
creation_date: 2019-09-15T07:16:49Z

[Term]
id: GO:0150119
name: negative regulation of protein localization to cell-cell junction
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc]
synonym: "negative regulation of protein localisation to cell-cell junction" EXACT []
is_a: GO:0150106 ! regulation of protein localization to cell-cell junction
is_a: GO:1903828 ! negative regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0150105 ! protein localization to cell-cell junction
relationship: negatively_regulates GO:0150105 ! protein localization to cell-cell junction
created_by: bc
creation_date: 2019-11-21T13:53:34Z

[Term]
id: GO:0150146
name: cell junction disassembly
namespace: biological_process
def: "The disaggregation of a cell junction into its constituent components." [GOC:aruk, PMID:25490267]
is_a: GO:0022411 ! cellular component disassembly
is_a: GO:0034330 ! cell junction organization
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0030054 ! cell junction
relationship: results_in_disassembly_of GO:0030054 ! cell junction
created_by: bc
creation_date: 2019-12-08T11:12:13Z

[Term]
id: GO:0150147
name: cell-cell junction disassembly
namespace: biological_process
def: "The disaggregation of a cell-cell junction into its constituent components." [GOC:aruk, PMID:25490267]
is_a: GO:0045216 ! cell-cell junction organization
is_a: GO:0150146 ! cell junction disassembly
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0005911 ! cell-cell junction
relationship: results_in_disassembly_of GO:0005911 ! cell-cell junction
created_by: bc
creation_date: 2019-12-08T11:16:14Z

[Term]
id: GO:0160038
name: somatic sensory system development
namespace: biological_process
def: "The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain." [PMID:25832476, PMID:31399790]
synonym: "somatosensory system development" EXACT []
is_a: GO:0048880 ! sensory system development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0003942 ! somatosensory system
relationship: results_in_development_of UBERON:0003942 ! somatosensory system
created_by: rynl
creation_date: 2022-07-07T16:49:26Z

[Term]
id: GO:0160043
name: catecholamine secretion, neurotransmission
namespace: biological_process
def: "The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter." [PMID:10191060]
is_a: GO:0007269 ! neurotransmitter secretion
is_a: GO:0050432 ! catecholamine secretion
intersection_of: GO:0007269 ! neurotransmitter secretion
intersection_of: has_primary_input CHEBI:33567 ! catecholamine
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23804" xsd:anyURI
created_by: rynl
creation_date: 2022-08-17T00:36:44Z

[Term]
id: GO:0160093
name: chordate pharynx development
namespace: biological_process
def: "The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure." [PMID:23020903]
is_a: GO:0060465 ! pharynx development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001042 ! chordate pharynx
relationship: results_in_development_of UBERON:0001042 ! chordate pharynx
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18285" xsd:anyURI
created_by: rynl
creation_date: 2023-08-29T21:05:28Z

[Term]
id: GO:1900015
name: regulation of cytokine production involved in inflammatory response
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie]
synonym: "regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie]
is_a: GO:0001817 ! regulation of cytokine production
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002534 ! cytokine production involved in inflammatory response
relationship: regulates GO:0002534 ! cytokine production involved in inflammatory response
created_by: rph
creation_date: 2012-01-11T09:34:27Z

[Term]
id: GO:1900016
name: negative regulation of cytokine production involved in inflammatory response
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie]
synonym: "down regulation of cytokine production involved in acute inflammatory response" BROAD [GOC:TermGenie]
synonym: "down regulation of cytokine production involved in inflammatory response" RELATED [GOC:TermGenie]
synonym: "negative regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie]
is_a: GO:0001818 ! negative regulation of cytokine production
is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002534 ! cytokine production involved in inflammatory response
relationship: negatively_regulates GO:0002534 ! cytokine production involved in inflammatory response
created_by: rph
creation_date: 2012-01-11T09:34:31Z

[Term]
id: GO:1900017
name: positive regulation of cytokine production involved in inflammatory response
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie]
synonym: "positive regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie]
synonym: "up regulation of cytokine production involved in acute inflammatory response" BROAD [GOC:TermGenie]
synonym: "up regulation of cytokine production involved in inflammatory response" RELATED [GOC:TermGenie]
is_a: GO:0001819 ! positive regulation of cytokine production
is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002534 ! cytokine production involved in inflammatory response
relationship: positively_regulates GO:0002534 ! cytokine production involved in inflammatory response
created_by: rph
creation_date: 2012-01-11T09:34:35Z

[Term]
id: GO:1900073
name: regulation of neuromuscular synaptic transmission
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie]
is_a: GO:0050804 ! modulation of chemical synaptic transmission
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007274 ! neuromuscular synaptic transmission
relationship: regulates GO:0007274 ! neuromuscular synaptic transmission
created_by: kmv
creation_date: 2012-01-26T10:14:10Z

[Term]
id: GO:1900074
name: negative regulation of neuromuscular synaptic transmission
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie]
synonym: "down regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie]
synonym: "down-regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie]
synonym: "downregulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie]
synonym: "inhibition of neuromuscular synaptic transmission" RELATED [GOC:TermGenie]
is_a: GO:0050805 ! negative regulation of synaptic transmission
is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007274 ! neuromuscular synaptic transmission
relationship: negatively_regulates GO:0007274 ! neuromuscular synaptic transmission
created_by: kmv
creation_date: 2012-01-26T10:14:18Z

[Term]
id: GO:1900075
name: positive regulation of neuromuscular synaptic transmission
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie]
synonym: "activation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie]
synonym: "up regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie]
synonym: "up-regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie]
synonym: "upregulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie]
is_a: GO:0050806 ! positive regulation of synaptic transmission
is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007274 ! neuromuscular synaptic transmission
relationship: positively_regulates GO:0007274 ! neuromuscular synaptic transmission
created_by: kmv
creation_date: 2012-01-26T10:14:22Z

[Term]
id: GO:1900115
name: extracellular regulation of signal transduction
namespace: biological_process
def: "Any regulation of signal transduction that takes place in the extracellular region." [GOC:signaling, GOC:TermGenie]
synonym: "regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie]
synonym: "regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie]
is_a: GO:0009966 ! regulation of signal transduction
intersection_of: GO:0009966 ! regulation of signal transduction
intersection_of: occurs_in GO:0005576 ! extracellular region
relationship: occurs_in GO:0005576 ! extracellular region
created_by: bf
creation_date: 2012-02-22T10:21:48Z

[Term]
id: GO:1900116
name: extracellular negative regulation of signal transduction
namespace: biological_process
def: "Any negative regulation of signal transduction that takes place in extracellular region." [GOC:signaling, GOC:TermGenie]
synonym: "down regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie]
synonym: "down-regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie]
synonym: "downregulation of signal transduction in extracellular region" EXACT [GOC:TermGenie]
synonym: "extracellular inhibition of signaling pathway" NARROW [GOC:bf]
synonym: "inhibition of signal transduction in extracellular region" NARROW [GOC:TermGenie]
synonym: "negative regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie]
synonym: "negative regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie]
is_a: GO:0009968 ! negative regulation of signal transduction
is_a: GO:1900115 ! extracellular regulation of signal transduction
intersection_of: GO:0009968 ! negative regulation of signal transduction
intersection_of: occurs_in GO:0005576 ! extracellular region
created_by: bf
creation_date: 2012-02-22T10:27:56Z

[Term]
id: GO:1900117
name: regulation of execution phase of apoptosis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie]
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097194 ! execution phase of apoptosis
relationship: regulates GO:0097194 ! execution phase of apoptosis
created_by: pr
creation_date: 2012-02-22T11:26:20Z

[Term]
id: GO:1900118
name: negative regulation of execution phase of apoptosis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie]
synonym: "down regulation of execution phase of apoptosis" EXACT [GOC:TermGenie]
synonym: "down-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie]
synonym: "downregulation of execution phase of apoptosis" EXACT [GOC:TermGenie]
synonym: "inhibition of execution phase of apoptosis" NARROW [GOC:TermGenie]
is_a: GO:0043066 ! negative regulation of apoptotic process
is_a: GO:1900117 ! regulation of execution phase of apoptosis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097194 ! execution phase of apoptosis
relationship: negatively_regulates GO:0097194 ! execution phase of apoptosis
created_by: pr
creation_date: 2012-02-22T11:26:24Z

[Term]
id: GO:1900119
name: positive regulation of execution phase of apoptosis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie]
synonym: "activation of execution phase of apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of execution phase of apoptosis" EXACT [GOC:TermGenie]
synonym: "up-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie]
synonym: "upregulation of execution phase of apoptosis" EXACT [GOC:TermGenie]
is_a: GO:0043065 ! positive regulation of apoptotic process
is_a: GO:1900117 ! regulation of execution phase of apoptosis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097194 ! execution phase of apoptosis
relationship: positively_regulates GO:0097194 ! execution phase of apoptosis
created_by: pr
creation_date: 2012-02-22T11:26:27Z

[Term]
id: GO:1900125
name: regulation of hyaluronan biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf]
synonym: "regulation of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "regulation of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "regulation of hyaluronan synthesis" EXACT [GOC:TermGenie]
is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030213 ! hyaluronan biosynthetic process
relationship: regulates GO:0030213 ! hyaluronan biosynthetic process
created_by: yaf
creation_date: 2012-02-23T01:09:21Z

[Term]
id: GO:1900126
name: negative regulation of hyaluronan biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf]
synonym: "down regulation of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "down regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down regulation of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "down regulation of hyaluronan synthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie]
synonym: "downregulation of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "downregulation of hyaluronan synthesis" EXACT [GOC:TermGenie]
synonym: "inhibition of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "inhibition of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "inhibition of hyaluronan biosynthetic process" NARROW [GOC:TermGenie]
synonym: "inhibition of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "inhibition of hyaluronan synthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of hyaluronan synthesis" EXACT [GOC:TermGenie]
is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process
is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process
is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process
is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030213 ! hyaluronan biosynthetic process
relationship: negatively_regulates GO:0030213 ! hyaluronan biosynthetic process
created_by: yaf
creation_date: 2012-02-23T01:09:29Z

[Term]
id: GO:1900127
name: positive regulation of hyaluronan biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf]
synonym: "activation of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "activation of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "activation of hyaluronan biosynthetic process" NARROW [GOC:TermGenie]
synonym: "activation of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "activation of hyaluronan synthesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "positive regulation of hyaluronan synthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up regulation of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "up regulation of hyaluronan synthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of hyaluronan anabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of hyaluronan formation" EXACT [GOC:TermGenie]
synonym: "upregulation of hyaluronan synthesis" EXACT [GOC:TermGenie]
is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process
is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process
is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process
is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030213 ! hyaluronan biosynthetic process
relationship: positively_regulates GO:0030213 ! hyaluronan biosynthetic process
created_by: yaf
creation_date: 2012-02-23T01:09:33Z

[Term]
id: GO:1900150
name: regulation of defense response to fungus
namespace: biological_process
alt_id: GO:2000072
def: "Any process that modulates the frequency, rate or extent of defense response to fungus." [GOC:dhl, GOC:TermGenie, PMID:22242006]
synonym: "regulation of defence response to fungi" EXACT [GOC:TermGenie]
synonym: "regulation of defence response to fungus" EXACT [GOC:TermGenie]
synonym: "regulation of defense response to fungi" EXACT [GOC:TermGenie]
synonym: "regulation of defense response to fungi, incompatible interaction" NARROW [GOC:obol]
synonym: "regulation of defense response to fungus, incompatible interaction" NARROW []
synonym: "regulation of resistance response to pathogenic fungi" NARROW [GOC:obol]
synonym: "regulation of resistance response to pathogenic fungus" NARROW [GOC:obol]
synonym: "regulation of response to pathogenic fungus (incompatible interaction)" NARROW [GOC:obol]
is_a: GO:0002831 ! regulation of response to biotic stimulus
is_a: GO:0031347 ! regulation of defense response
is_a: GO:0032101 ! regulation of response to external stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0050832 ! defense response to fungus
relationship: regulates GO:0050832 ! defense response to fungus
created_by: dhl
creation_date: 2012-03-06T10:00:16Z

[Term]
id: GO:1900180
name: regulation of protein localization to nucleus
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie]
synonym: "regulation of protein localisation to nucleus" EXACT [GOC:TermGenie]
synonym: "regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie]
synonym: "regulation of protein localization in nucleus" EXACT [GOC:TermGenie]
is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0034504 ! protein localization to nucleus
relationship: regulates GO:0034504 ! protein localization to nucleus
created_by: bf
creation_date: 2012-03-12T01:23:44Z

[Term]
id: GO:1900181
name: negative regulation of protein localization to nucleus
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie]
synonym: "down regulation of protein localisation to nucleus" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization in nucleus" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization to nucleus" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization in nucleus" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to nucleus" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation to nucleus" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization in nucleus" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to nucleus" EXACT [GOC:TermGenie]
synonym: "inhibition of protein localisation to nucleus" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization in cell nucleus" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization in nucleus" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization to nucleus" NARROW [GOC:TermGenie]
synonym: "negative regulation of protein localisation to nucleus" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localization in nucleus" EXACT [GOC:TermGenie]
is_a: GO:1900180 ! regulation of protein localization to nucleus
is_a: GO:1903828 ! negative regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0034504 ! protein localization to nucleus
relationship: negatively_regulates GO:0034504 ! protein localization to nucleus
created_by: bf
creation_date: 2012-03-12T01:23:48Z

[Term]
id: GO:1900182
name: positive regulation of protein localization to nucleus
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie]
synonym: "activation of protein localisation to nucleus" NARROW [GOC:TermGenie]
synonym: "activation of protein localization in cell nucleus" NARROW [GOC:TermGenie]
synonym: "activation of protein localization in nucleus" EXACT [GOC:TermGenie]
synonym: "activation of protein localization to nucleus" NARROW [GOC:TermGenie]
synonym: "positive regulation of protein localisation to nucleus" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localization in nucleus" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation to nucleus" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization in nucleus" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization to nucleus" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization in nucleus" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to nucleus" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation to nucleus" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization in nucleus" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to nucleus" EXACT [GOC:TermGenie]
is_a: GO:1900180 ! regulation of protein localization to nucleus
is_a: GO:1903829 ! positive regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0034504 ! protein localization to nucleus
relationship: positively_regulates GO:0034504 ! protein localization to nucleus
created_by: bf
creation_date: 2012-03-12T01:23:52Z

[Term]
id: GO:1900193
name: regulation of oocyte maturation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie]
is_a: GO:1903429 ! regulation of cell maturation
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001556 ! oocyte maturation
relationship: regulates GO:0001556 ! oocyte maturation
created_by: kmv
creation_date: 2012-03-19T09:41:18Z

[Term]
id: GO:1900194
name: negative regulation of oocyte maturation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie]
synonym: "down regulation of oocyte maturation" EXACT [GOC:TermGenie]
synonym: "down-regulation of oocyte maturation" EXACT [GOC:TermGenie]
synonym: "downregulation of oocyte maturation" EXACT [GOC:TermGenie]
synonym: "inhibition of oocyte maturation" NARROW [GOC:TermGenie]
is_a: GO:1900193 ! regulation of oocyte maturation
is_a: GO:1903430 ! negative regulation of cell maturation
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001556 ! oocyte maturation
relationship: negatively_regulates GO:0001556 ! oocyte maturation
created_by: kmv
creation_date: 2012-03-19T09:41:27Z

[Term]
id: GO:1900195
name: positive regulation of oocyte maturation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie]
synonym: "activation of oocyte maturation" NARROW [GOC:TermGenie]
synonym: "up regulation of oocyte maturation" EXACT [GOC:TermGenie]
synonym: "up-regulation of oocyte maturation" EXACT [GOC:TermGenie]
synonym: "upregulation of oocyte maturation" EXACT [GOC:TermGenie]
is_a: GO:1900193 ! regulation of oocyte maturation
is_a: GO:1903431 ! positive regulation of cell maturation
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001556 ! oocyte maturation
relationship: positively_regulates GO:0001556 ! oocyte maturation
created_by: kmv
creation_date: 2012-03-19T09:41:35Z

[Term]
id: GO:1900200
name: mesenchymal cell apoptotic process involved in metanephros development
namespace: biological_process
def: "Any mesenchymal cell apoptotic process that is involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "mesenchymal cell apoptosis involved in metanephros development" NARROW []
is_a: GO:0097152 ! mesenchymal cell apoptotic process
is_a: GO:1902742 ! apoptotic process involved in development
intersection_of: GO:0097152 ! mesenchymal cell apoptotic process
intersection_of: part_of GO:0001656 ! metanephros development
relationship: part_of GO:0001656 ! metanephros development
created_by: yaf
creation_date: 2012-03-21T11:58:05Z

[Term]
id: GO:1900204
name: apoptotic process involved in metanephric collecting duct development
namespace: biological_process
def: "Any apoptotic process that is involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
is_a: GO:1902742 ! apoptotic process involved in development
intersection_of: GO:0006915 ! apoptotic process
intersection_of: part_of GO:0072205 ! metanephric collecting duct development
relationship: part_of GO:0072205 ! metanephric collecting duct development
created_by: yaf
creation_date: 2012-03-21T01:21:32Z

[Term]
id: GO:1900205
name: apoptotic process involved in metanephric nephron tubule development
namespace: biological_process
def: "Any apoptotic process that is involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
is_a: GO:1902742 ! apoptotic process involved in development
intersection_of: GO:0006915 ! apoptotic process
intersection_of: part_of GO:0072234 ! metanephric nephron tubule development
relationship: part_of GO:0072234 ! metanephric nephron tubule development
created_by: yaf
creation_date: 2012-03-21T01:21:45Z

[Term]
id: GO:1900206
name: regulation of pronephric nephron tubule development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of pronephric nephron tubule development." [GOC:TermGenie]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0039020 ! pronephric nephron tubule development
relationship: regulates GO:0039020 ! pronephric nephron tubule development
created_by: bf
creation_date: 2012-03-22T09:23:13Z

[Term]
id: GO:1900207
name: negative regulation of pronephric nephron tubule development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development." [GOC:bf, GOC:TermGenie, PMID:9758706]
synonym: "down regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down-regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "downregulation of pronephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "inhibition of pronephric nephron tubule development" NARROW [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:1900206 ! regulation of pronephric nephron tubule development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0039020 ! pronephric nephron tubule development
relationship: negatively_regulates GO:0039020 ! pronephric nephron tubule development
created_by: bf
creation_date: 2012-03-22T09:23:23Z

[Term]
id: GO:1900211
name: regulation of mesenchymal cell apoptotic process involved in metanephros development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW []
is_a: GO:1904748 ! regulation of apoptotic process involved in development
is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development
relationship: regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development
created_by: yaf
creation_date: 2012-03-22T10:52:50Z

[Term]
id: GO:1900212
name: negative regulation of mesenchymal cell apoptotic process involved in metanephros development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "down regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie]
synonym: "down-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie]
synonym: "downregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie]
synonym: "inhibition of mesenchymal cell apoptosis involved in metanephros development" NARROW [GOC:TermGenie]
synonym: "negative regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW []
is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development
is_a: GO:1904746 ! negative regulation of apoptotic process involved in development
is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development
relationship: negatively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development
created_by: yaf
creation_date: 2012-03-22T10:53:00Z

[Term]
id: GO:1900213
name: positive regulation of mesenchymal cell apoptotic process involved in metanephros development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "activation of mesenchymal cell apoptosis involved in metanephros development" NARROW [GOC:TermGenie]
synonym: "positive regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW []
synonym: "up regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie]
synonym: "up-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie]
synonym: "upregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie]
is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development
is_a: GO:1904747 ! positive regulation of apoptotic process involved in development
is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development
relationship: positively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development
created_by: yaf
creation_date: 2012-03-22T10:53:09Z

[Term]
id: GO:1900214
name: regulation of apoptotic process involved in metanephric collecting duct development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
is_a: GO:1904748 ! regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development
relationship: regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development
created_by: yaf
creation_date: 2012-03-22T10:53:21Z

[Term]
id: GO:1900215
name: negative regulation of apoptotic process involved in metanephric collecting duct development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "down regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "down regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "down regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "down regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "down-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "down-regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "down-regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "downregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "downregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "downregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "inhibition of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "inhibition of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "inhibition of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "inhibition of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "inhibition of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "negative regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "negative regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "negative regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "negative regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "negative regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development
is_a: GO:1904746 ! negative regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development
relationship: negatively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development
created_by: yaf
creation_date: 2012-03-22T10:53:31Z

[Term]
id: GO:1900216
name: positive regulation of apoptotic process involved in metanephric collecting duct development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "activation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "activation of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "activation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "activation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "activation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "activation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "positive regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "positive regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "positive regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "positive regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "positive regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "up regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "up regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "up regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "up-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "up-regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "up-regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "upregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie]
synonym: "upregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie]
synonym: "upregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie]
is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development
is_a: GO:1904747 ! positive regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development
relationship: positively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development
created_by: yaf
creation_date: 2012-03-22T10:53:39Z

[Term]
id: GO:1900217
name: regulation of apoptotic process involved in metanephric nephron tubule development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
is_a: GO:1904748 ! regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development
relationship: regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development
created_by: yaf
creation_date: 2012-03-22T10:53:51Z

[Term]
id: GO:1900218
name: negative regulation of apoptotic process involved in metanephric nephron tubule development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "down regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "down regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "down-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "down-regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "downregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "downregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "downregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "inhibition of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "inhibition of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "inhibition of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "inhibition of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "inhibition of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "negative regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "negative regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "negative regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "negative regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development
is_a: GO:1904746 ! negative regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development
relationship: negatively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development
created_by: yaf
creation_date: 2012-03-22T10:54:01Z

[Term]
id: GO:1900219
name: positive regulation of apoptotic process involved in metanephric nephron tubule development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325]
synonym: "activation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "activation of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "activation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "activation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "activation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "activation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "positive regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "positive regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "positive regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "positive regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "up regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "up regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "up regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "up-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "up-regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "upregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie]
synonym: "upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie]
synonym: "upregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie]
is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development
is_a: GO:1904747 ! positive regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development
relationship: positively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development
created_by: yaf
creation_date: 2012-03-22T10:54:09Z

[Term]
id: GO:1900366
name: negative regulation of defense response to insect
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183]
synonym: "down regulation of defense response to insect" EXACT [GOC:TermGenie]
synonym: "down regulation of physiological defense response to insect" EXACT [GOC:TermGenie]
synonym: "down-regulation of defense response to insect" EXACT [GOC:TermGenie]
synonym: "down-regulation of physiological defense response to insect" EXACT [GOC:TermGenie]
synonym: "downregulation of defense response to insect" EXACT [GOC:TermGenie]
synonym: "downregulation of physiological defense response to insect" EXACT [GOC:TermGenie]
synonym: "inhibition of defense response to insect" NARROW [GOC:TermGenie]
synonym: "inhibition of physiological defense response to insect" NARROW [GOC:TermGenie]
synonym: "negative regulation of physiological defense response to insect" EXACT [GOC:TermGenie]
synonym: "susceptibility to insect" RELATED []
is_a: GO:0031348 ! negative regulation of defense response
is_a: GO:2000068 ! regulation of defense response to insect
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002213 ! defense response to insect
relationship: negatively_regulates GO:0002213 ! defense response to insect
created_by: dhl
creation_date: 2012-04-12T04:44:00Z

[Term]
id: GO:1900367
name: positive regulation of defense response to insect
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183]
synonym: "activation of defense response to insect" NARROW [GOC:TermGenie]
synonym: "activation of physiological defense response to insect" NARROW [GOC:TermGenie]
synonym: "positive regulation of physiological defense response to insect" EXACT [GOC:TermGenie]
synonym: "up regulation of defense response to insect" EXACT [GOC:TermGenie]
synonym: "up regulation of physiological defense response to insect" EXACT [GOC:TermGenie]
synonym: "up-regulation of defense response to insect" EXACT [GOC:TermGenie]
synonym: "up-regulation of physiological defense response to insect" EXACT [GOC:TermGenie]
synonym: "upregulation of defense response to insect" EXACT [GOC:TermGenie]
synonym: "upregulation of physiological defense response to insect" EXACT [GOC:TermGenie]
is_a: GO:0031349 ! positive regulation of defense response
is_a: GO:2000068 ! regulation of defense response to insect
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002213 ! defense response to insect
relationship: positively_regulates GO:0002213 ! defense response to insect
created_by: dhl
creation_date: 2012-04-12T04:44:10Z

[Term]
id: GO:1900376
name: regulation of secondary metabolite biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie]
synonym: "regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
is_a: GO:0009889 ! regulation of biosynthetic process
is_a: GO:0043455 ! regulation of secondary metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0044550 ! secondary metabolite biosynthetic process
relationship: regulates GO:0044550 ! secondary metabolite biosynthetic process
created_by: di
creation_date: 2012-04-17T01:55:23Z

[Term]
id: GO:1900377
name: negative regulation of secondary metabolite biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie]
synonym: "down regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
synonym: "down regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie]
synonym: "downregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie]
synonym: "inhibition of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
synonym: "inhibition of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie]
synonym: "negative regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
is_a: GO:0009890 ! negative regulation of biosynthetic process
is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0044550 ! secondary metabolite biosynthetic process
relationship: negatively_regulates GO:0044550 ! secondary metabolite biosynthetic process
created_by: di
creation_date: 2012-04-17T01:55:32Z

[Term]
id: GO:1900378
name: positive regulation of secondary metabolite biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie]
synonym: "activation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
synonym: "activation of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie]
synonym: "positive regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie]
is_a: GO:0009891 ! positive regulation of biosynthetic process
is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0044550 ! secondary metabolite biosynthetic process
relationship: positively_regulates GO:0044550 ! secondary metabolite biosynthetic process
created_by: di
creation_date: 2012-04-17T01:55:41Z

[Term]
id: GO:1900424
name: regulation of defense response to bacterium
namespace: biological_process
alt_id: GO:1902477
def: "Any process that modulates the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749]
synonym: "regulation of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "regulation of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "regulation of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "regulation of defence response to bacterium, incompatible interaction" NARROW [GOC:TermGenie]
synonym: "regulation of defence response to pathogenic bacteria, incompatible interaction" NARROW [GOC:TermGenie]
synonym: "regulation of defence response to pathogenic bacterium, incompatible interaction" NARROW [GOC:TermGenie]
synonym: "regulation of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "regulation of defense response to bacterium, incompatible interaction" NARROW []
synonym: "regulation of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie]
synonym: "regulation of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie]
is_a: GO:0002831 ! regulation of response to biotic stimulus
is_a: GO:0031347 ! regulation of defense response
is_a: GO:0032101 ! regulation of response to external stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042742 ! defense response to bacterium
relationship: regulates GO:0042742 ! defense response to bacterium
created_by: dhl
creation_date: 2012-04-24T10:12:43Z

[Term]
id: GO:1900425
name: negative regulation of defense response to bacterium
namespace: biological_process
alt_id: GO:1902478
def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749]
synonym: "down regulation of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "down regulation of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "down regulation of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "down regulation of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "down regulation of defense response to bacterium" EXACT [GOC:TermGenie]
synonym: "down-regulation of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "down-regulation of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "down-regulation of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "down-regulation of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "down-regulation of defense response to bacterium" EXACT [GOC:TermGenie]
synonym: "downregulation of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "downregulation of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "downregulation of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "downregulation of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "downregulation of defense response to bacterium" EXACT [GOC:TermGenie]
synonym: "inhibition of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "inhibition of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "inhibition of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "inhibition of defence response to pathogenic bacteria, incompatible interaction" NARROW [GOC:TermGenie]
synonym: "inhibition of defence response to pathogenic bacterium, incompatible interaction" NARROW [GOC:TermGenie]
synonym: "inhibition of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "inhibition of defense response to bacterium" NARROW [GOC:TermGenie]
synonym: "inhibition of defense response to bacterium, incompatible interaction" NARROW [GOC:TermGenie]
synonym: "inhibition of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie]
synonym: "inhibition of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie]
synonym: "inhibition of response to pathogenic bacteria (incompatible interaction)" NARROW [GOC:TermGenie]
synonym: "inhibition of response to pathogenic bacterium (incompatible interaction)" NARROW [GOC:TermGenie]
synonym: "negative regulation of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "negative regulation of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "negative regulation of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "negative regulation of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "negative regulation of defense response to bacterium, incompatible interaction" NARROW []
is_a: GO:0002832 ! negative regulation of response to biotic stimulus
is_a: GO:0031348 ! negative regulation of defense response
is_a: GO:0032102 ! negative regulation of response to external stimulus
is_a: GO:1900424 ! regulation of defense response to bacterium
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042742 ! defense response to bacterium
relationship: negatively_regulates GO:0042742 ! defense response to bacterium
created_by: dhl
creation_date: 2012-04-24T10:12:54Z

[Term]
id: GO:1900426
name: positive regulation of defense response to bacterium
namespace: biological_process
alt_id: GO:1902479
def: "Any process that activates or increases the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749]
synonym: "activation of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "activation of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "activation of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "activation of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "activation of defense response to bacterium" NARROW [GOC:TermGenie]
synonym: "activation of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie]
synonym: "activation of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie]
synonym: "positive regulation of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "positive regulation of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "positive regulation of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "positive regulation of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "positive regulation of defense response to bacterium, incompatible interaction" NARROW []
synonym: "up regulation of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "up regulation of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "up regulation of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "up regulation of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "up regulation of defense response to bacterium" EXACT [GOC:TermGenie]
synonym: "up-regulation of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "up-regulation of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "up-regulation of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "up-regulation of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "up-regulation of defense response to bacterium" EXACT [GOC:TermGenie]
synonym: "upregulation of antibacterial peptide activity" RELATED [GOC:TermGenie]
synonym: "upregulation of defence response to bacteria" EXACT [GOC:TermGenie]
synonym: "upregulation of defence response to bacterium" EXACT [GOC:TermGenie]
synonym: "upregulation of defense response to bacteria" EXACT [GOC:TermGenie]
synonym: "upregulation of defense response to bacterium" EXACT [GOC:TermGenie]
is_a: GO:0002833 ! positive regulation of response to biotic stimulus
is_a: GO:0031349 ! positive regulation of defense response
is_a: GO:0032103 ! positive regulation of response to external stimulus
is_a: GO:1900424 ! regulation of defense response to bacterium
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0042742 ! defense response to bacterium
relationship: positively_regulates GO:0042742 ! defense response to bacterium
created_by: dhl
creation_date: 2012-04-24T10:13:13Z

[Term]
id: GO:1900619
name: acetate ester metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie]
synonym: "acetate ester metabolism" EXACT [GOC:TermGenie]
synonym: "acetyl ester metabolic process" EXACT [CHEBI:47622]
synonym: "acetyl ester metabolism" EXACT [CHEBI:47622]
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:47622 ! acetate ester
relationship: has_primary_input_or_output CHEBI:47622 ! acetate ester
created_by: bf
creation_date: 2012-05-16T12:29:51Z

[Term]
id: GO:1900620
name: acetate ester biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie, PMID:15042596]
synonym: "acetate ester anabolism" EXACT [GOC:TermGenie]
synonym: "acetate ester biosynthesis" EXACT [GOC:TermGenie]
synonym: "acetate ester formation" EXACT [GOC:TermGenie]
synonym: "acetate ester synthesis" EXACT [GOC:TermGenie]
synonym: "acetyl ester biosynthesis" EXACT [CHEBI:47622]
synonym: "acetyl ester biosynthetic process" EXACT [CHEBI:47622]
is_a: GO:1900619 ! acetate ester metabolic process
is_a: GO:1901576 ! organic substance biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:47622 ! acetate ester
relationship: has_primary_output CHEBI:47622 ! acetate ester
created_by: bf
creation_date: 2012-05-16T12:30:12Z

[Term]
id: GO:1901071
name: glucosamine-containing compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines)." [GOC:TermGenie]
synonym: "glucosamine-containing compound metabolism" EXACT [GOC:bf]
synonym: "glucosamines metabolic process" EXACT [CHEBI:24271]
synonym: "glucosamines metabolism" EXACT [GOC:TermGenie]
is_a: GO:0006040 ! amino sugar metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:24271 ! glucosamines
relationship: has_primary_input_or_output CHEBI:24271 ! glucosamines
created_by: bf
creation_date: 2012-07-02T03:18:04Z

[Term]
id: GO:1901072
name: glucosamine-containing compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines)." [GOC:TermGenie]
synonym: "glucosamine-containing compound breakdown" EXACT [GOC:bf]
synonym: "glucosamine-containing compound catabolism" EXACT [GOC:bf]
synonym: "glucosamine-containing compound degradation" EXACT [GOC:bf]
synonym: "glucosamines breakdown" EXACT [GOC:TermGenie]
synonym: "glucosamines catabolic process" EXACT [CHEBI:24271]
synonym: "glucosamines catabolism" EXACT [GOC:TermGenie]
synonym: "glucosamines degradation" EXACT [GOC:TermGenie]
is_a: GO:0046348 ! amino sugar catabolic process
is_a: GO:1901071 ! glucosamine-containing compound metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:24271 ! glucosamines
relationship: has_primary_input CHEBI:24271 ! glucosamines
created_by: bf
creation_date: 2012-07-02T03:18:25Z

[Term]
id: GO:1901073
name: glucosamine-containing compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines)." [GOC:TermGenie]
synonym: "glucosamine-containing compound anabolism" EXACT [GOC:bf]
synonym: "glucosamine-containing compound biosynthesis" EXACT [GOC:bf]
synonym: "glucosamine-containing compound formation" EXACT [GOC:bf]
synonym: "glucosamine-containing compound synthesis" EXACT [GOC:bf]
synonym: "glucosamines anabolism" EXACT [GOC:TermGenie]
synonym: "glucosamines biosynthesis" EXACT [GOC:TermGenie]
synonym: "glucosamines biosynthetic process" EXACT [CHEBI:24271]
synonym: "glucosamines formation" EXACT [GOC:TermGenie]
synonym: "glucosamines synthesis" EXACT [GOC:TermGenie]
is_a: GO:0046349 ! amino sugar biosynthetic process
is_a: GO:1901071 ! glucosamine-containing compound metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:24271 ! glucosamines
relationship: has_primary_output CHEBI:24271 ! glucosamines
created_by: bf
creation_date: 2012-07-02T03:18:33Z

[Term]
id: GO:1901135
name: carbohydrate derivative metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving carbohydrate derivative." [GOC:TermGenie]
subset: goslim_agr
subset: goslim_generic
subset: goslim_mouse
subset: goslim_prokaryote
synonym: "carbohydrate derivative metabolism" EXACT [GOC:TermGenie]
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:63299 ! carbohydrate derivative
relationship: has_primary_input_or_output CHEBI:63299 ! carbohydrate derivative
created_by: bf
creation_date: 2012-07-12T04:05:09Z

[Term]
id: GO:1901136
name: carbohydrate derivative catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative." [GOC:TermGenie]
synonym: "carbohydrate derivative breakdown" EXACT [GOC:TermGenie]
synonym: "carbohydrate derivative catabolism" EXACT [GOC:TermGenie]
synonym: "carbohydrate derivative degradation" EXACT [GOC:TermGenie]
is_a: GO:1901135 ! carbohydrate derivative metabolic process
is_a: GO:1901575 ! organic substance catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative
relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative
created_by: bf
creation_date: 2012-07-12T04:05:31Z

[Term]
id: GO:1901137
name: carbohydrate derivative biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of carbohydrate derivative." [GOC:TermGenie]
synonym: "carbohydrate derivative anabolism" EXACT [GOC:TermGenie]
synonym: "carbohydrate derivative biosynthesis" EXACT [GOC:TermGenie]
synonym: "carbohydrate derivative formation" EXACT [GOC:TermGenie]
synonym: "carbohydrate derivative synthesis" EXACT [GOC:TermGenie]
is_a: GO:1901135 ! carbohydrate derivative metabolic process
is_a: GO:1901576 ! organic substance biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:63299 ! carbohydrate derivative
relationship: has_primary_output CHEBI:63299 ! carbohydrate derivative
created_by: bf
creation_date: 2012-07-12T04:05:39Z

[Term]
id: GO:1901142
name: insulin metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving insulin." [GOC:TermGenie]
synonym: "insulin metabolism" EXACT [GOC:TermGenie]
is_a: GO:0019538 ! protein metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output PR:000009054 ! insulin gene translation product
relationship: has_primary_input_or_output PR:000009054 ! insulin gene translation product
property_value: RO:0002161 NCBITaxon:33090
property_value: RO:0002161 NCBITaxon_Union:0000023
created_by: pm
creation_date: 2012-07-13T12:32:40Z

[Term]
id: GO:1901143
name: insulin catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of insulin." [GOC:TermGenie]
synonym: "insulin breakdown" EXACT [GOC:TermGenie]
synonym: "insulin catabolism" EXACT [GOC:TermGenie]
synonym: "insulin degradation" EXACT [GOC:TermGenie]
is_a: GO:0030163 ! protein catabolic process
is_a: GO:1901142 ! insulin metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input PR:000009054 ! insulin gene translation product
relationship: has_primary_input PR:000009054 ! insulin gene translation product
created_by: pm
creation_date: 2012-07-13T12:33:03Z

[Term]
id: GO:1901145
name: mesenchymal cell apoptotic process involved in nephron morphogenesis
namespace: biological_process
def: "Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie]
is_a: GO:0060561 ! apoptotic process involved in morphogenesis
is_a: GO:0097152 ! mesenchymal cell apoptotic process
intersection_of: GO:0097152 ! mesenchymal cell apoptotic process
intersection_of: part_of GO:0072028 ! nephron morphogenesis
relationship: part_of GO:0072028 ! nephron morphogenesis
created_by: pr
creation_date: 2012-07-13T01:43:51Z

[Term]
id: GO:1901146
name: mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
namespace: biological_process
def: "Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie]
is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis
intersection_of: GO:0097152 ! mesenchymal cell apoptotic process
intersection_of: part_of GO:0061228 ! mesonephric nephron morphogenesis
relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis
created_by: pr
creation_date: 2012-07-13T02:40:43Z

[Term]
id: GO:1901147
name: mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
namespace: biological_process
def: "Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie]
is_a: GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development
is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis
intersection_of: GO:0097152 ! mesenchymal cell apoptotic process
intersection_of: part_of GO:0072273 ! metanephric nephron morphogenesis
relationship: part_of GO:0072273 ! metanephric nephron morphogenesis
created_by: pr
creation_date: 2012-07-13T02:41:12Z

[Term]
id: GO:1901148
name: gene expression involved in extracellular matrix organization
namespace: biological_process
def: "Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form." [GOC:pg, GOC:TermGenie, PMID:18668558]
synonym: "expression of extracellular matrix proteins" EXACT [GOC:bf]
synonym: "extracellular matrix protein production" RELATED [GOC:pg]
is_a: GO:0010467 ! gene expression
intersection_of: GO:0010467 ! gene expression
intersection_of: part_of GO:0030198 ! extracellular matrix organization
relationship: part_of GO:0030198 ! extracellular matrix organization
created_by: bf
creation_date: 2012-07-16T03:29:30Z

[Term]
id: GO:1901160
name: primary amino compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving primary amino compound." [GOC:TermGenie]
synonym: "primary amino compound metabolism" EXACT [GOC:TermGenie]
is_a: GO:1901564 ! organonitrogen compound metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:50994 ! primary amino compound
relationship: has_primary_input_or_output CHEBI:50994 ! primary amino compound
created_by: bf
creation_date: 2012-07-18T04:44:39Z

[Term]
id: GO:1901161
name: primary amino compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of primary amino compound." [GOC:TermGenie]
synonym: "primary amino compound breakdown" EXACT [GOC:TermGenie]
synonym: "primary amino compound catabolism" EXACT [GOC:TermGenie]
synonym: "primary amino compound degradation" EXACT [GOC:TermGenie]
is_a: GO:1901160 ! primary amino compound metabolic process
is_a: GO:1901565 ! organonitrogen compound catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:50994 ! primary amino compound
relationship: has_primary_input CHEBI:50994 ! primary amino compound
created_by: bf
creation_date: 2012-07-18T04:45:06Z

[Term]
id: GO:1901162
name: primary amino compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of primary amino compound." [GOC:TermGenie]
synonym: "primary amino compound anabolism" EXACT [GOC:TermGenie]
synonym: "primary amino compound biosynthesis" EXACT [GOC:TermGenie]
synonym: "primary amino compound formation" EXACT [GOC:TermGenie]
synonym: "primary amino compound synthesis" EXACT [GOC:TermGenie]
is_a: GO:1901160 ! primary amino compound metabolic process
is_a: GO:1901566 ! organonitrogen compound biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:50994 ! primary amino compound
relationship: has_primary_output CHEBI:50994 ! primary amino compound
created_by: bf
creation_date: 2012-07-18T04:45:14Z

[Term]
id: GO:1901163
name: regulation of trophoblast cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie]
is_a: GO:0030334 ! regulation of cell migration
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061450 ! trophoblast cell migration
relationship: regulates GO:0061450 ! trophoblast cell migration
created_by: vk
creation_date: 2012-07-19T07:53:06Z

[Term]
id: GO:1901164
name: negative regulation of trophoblast cell migration
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie]
synonym: "down regulation of trophoblast cell migration" EXACT [GOC:TermGenie]
synonym: "down-regulation of trophoblast cell migration" EXACT [GOC:TermGenie]
synonym: "downregulation of trophoblast cell migration" EXACT [GOC:TermGenie]
synonym: "inhibition of trophoblast cell migration" NARROW [GOC:TermGenie]
is_a: GO:0030336 ! negative regulation of cell migration
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1901163 ! regulation of trophoblast cell migration
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061450 ! trophoblast cell migration
relationship: negatively_regulates GO:0061450 ! trophoblast cell migration
created_by: vk
creation_date: 2012-07-19T07:53:28Z

[Term]
id: GO:1901165
name: positive regulation of trophoblast cell migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie]
synonym: "activation of trophoblast cell migration" NARROW [GOC:TermGenie]
synonym: "up regulation of trophoblast cell migration" EXACT [GOC:TermGenie]
synonym: "up-regulation of trophoblast cell migration" EXACT [GOC:TermGenie]
synonym: "upregulation of trophoblast cell migration" EXACT [GOC:TermGenie]
is_a: GO:0030335 ! positive regulation of cell migration
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1901163 ! regulation of trophoblast cell migration
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061450 ! trophoblast cell migration
relationship: positively_regulates GO:0061450 ! trophoblast cell migration
created_by: vk
creation_date: 2012-07-19T07:53:35Z

[Term]
id: GO:1901166
name: neural crest cell migration involved in autonomic nervous system development
namespace: biological_process
def: "Any neural crest cell migration that is involved in autonomic nervous system development." [GOC:BHF, GOC:TermGenie]
is_a: GO:0001755 ! neural crest cell migration
intersection_of: GO:0001755 ! neural crest cell migration
intersection_of: part_of GO:0048483 ! autonomic nervous system development
relationship: part_of GO:0048483 ! autonomic nervous system development
created_by: vk
creation_date: 2012-07-19T08:39:56Z

[Term]
id: GO:1901190
name: regulation of formation of translation initiation ternary complex
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie]
synonym: "regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
is_a: GO:0043254 ! regulation of protein-containing complex assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001677 ! formation of translation initiation ternary complex
relationship: regulates GO:0001677 ! formation of translation initiation ternary complex
created_by: ss
creation_date: 2012-07-25T02:26:58Z

[Term]
id: GO:1901191
name: negative regulation of formation of translation initiation ternary complex
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie]
synonym: "down regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie]
synonym: "down regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie]
synonym: "down-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie]
synonym: "downregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
synonym: "inhibition of formation of translation initiation ternary complex" NARROW [GOC:TermGenie]
synonym: "inhibition of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
synonym: "negative regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
is_a: GO:0031333 ! negative regulation of protein-containing complex assembly
is_a: GO:0045947 ! negative regulation of translational initiation
is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001677 ! formation of translation initiation ternary complex
relationship: negatively_regulates GO:0001677 ! formation of translation initiation ternary complex
created_by: ss
creation_date: 2012-07-25T02:27:21Z

[Term]
id: GO:1901192
name: positive regulation of formation of translation initiation ternary complex
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie]
synonym: "activation of formation of translation initiation ternary complex" NARROW [GOC:TermGenie]
synonym: "activation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
synonym: "positive regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
synonym: "up regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie]
synonym: "up regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie]
synonym: "up-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie]
synonym: "upregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie]
is_a: GO:0031334 ! positive regulation of protein-containing complex assembly
is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001677 ! formation of translation initiation ternary complex
relationship: positively_regulates GO:0001677 ! formation of translation initiation ternary complex
created_by: ss
creation_date: 2012-07-25T02:27:29Z

[Term]
id: GO:1901201
name: regulation of extracellular matrix assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie]
is_a: GO:0044087 ! regulation of cellular component biogenesis
is_a: GO:1903053 ! regulation of extracellular matrix organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0085029 ! extracellular matrix assembly
relationship: regulates GO:0085029 ! extracellular matrix assembly
created_by: rl
creation_date: 2012-07-27T04:04:00Z

[Term]
id: GO:1901202
name: negative regulation of extracellular matrix assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie]
synonym: "down regulation of extracellular matrix assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of extracellular matrix assembly" EXACT [GOC:TermGenie]
synonym: "inhibition of extracellular matrix assembly" NARROW [GOC:TermGenie]
is_a: GO:1901201 ! regulation of extracellular matrix assembly
is_a: GO:1903054 ! negative regulation of extracellular matrix organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0085029 ! extracellular matrix assembly
relationship: negatively_regulates GO:0085029 ! extracellular matrix assembly
created_by: rl
creation_date: 2012-07-27T04:04:24Z

[Term]
id: GO:1901203
name: positive regulation of extracellular matrix assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie]
synonym: "activation of extracellular matrix assembly" NARROW [GOC:TermGenie]
synonym: "up regulation of extracellular matrix assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of extracellular matrix assembly" EXACT [GOC:TermGenie]
is_a: GO:0044089 ! positive regulation of cellular component biogenesis
is_a: GO:1901201 ! regulation of extracellular matrix assembly
is_a: GO:1903055 ! positive regulation of extracellular matrix organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0085029 ! extracellular matrix assembly
relationship: positively_regulates GO:0085029 ! extracellular matrix assembly
created_by: rl
creation_date: 2012-07-27T04:04:32Z

[Term]
id: GO:1901210
name: regulation of cardiac chamber formation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie]
synonym: "regulation of heart chamber formation" EXACT [GOC:TermGenie]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003207 ! cardiac chamber formation
relationship: regulates GO:0003207 ! cardiac chamber formation
created_by: rl
creation_date: 2012-07-31T07:18:35Z

[Term]
id: GO:1901211
name: negative regulation of cardiac chamber formation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie]
synonym: "down regulation of cardiac chamber formation" EXACT [GOC:TermGenie]
synonym: "down regulation of heart chamber formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiac chamber formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of heart chamber formation" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiac chamber formation" EXACT [GOC:TermGenie]
synonym: "downregulation of heart chamber formation" EXACT [GOC:TermGenie]
synonym: "inhibition of cardiac chamber formation" NARROW [GOC:TermGenie]
synonym: "inhibition of heart chamber formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of heart chamber formation" EXACT [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:1901210 ! regulation of cardiac chamber formation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003207 ! cardiac chamber formation
relationship: negatively_regulates GO:0003207 ! cardiac chamber formation
created_by: rl
creation_date: 2012-07-31T07:18:57Z

[Term]
id: GO:1901212
name: positive regulation of cardiac chamber formation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie]
synonym: "activation of cardiac chamber formation" NARROW [GOC:TermGenie]
synonym: "activation of heart chamber formation" EXACT [GOC:TermGenie]
synonym: "positive regulation of heart chamber formation" EXACT [GOC:TermGenie]
synonym: "up regulation of cardiac chamber formation" EXACT [GOC:TermGenie]
synonym: "up regulation of heart chamber formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of cardiac chamber formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of heart chamber formation" EXACT [GOC:TermGenie]
synonym: "upregulation of cardiac chamber formation" EXACT [GOC:TermGenie]
synonym: "upregulation of heart chamber formation" EXACT [GOC:TermGenie]
is_a: GO:1901210 ! regulation of cardiac chamber formation
is_a: GO:1901221 ! positive regulation of cardiac chamber morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003207 ! cardiac chamber formation
relationship: positively_regulates GO:0003207 ! cardiac chamber formation
created_by: rl
creation_date: 2012-07-31T07:19:05Z

[Term]
id: GO:1901219
name: regulation of cardiac chamber morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie]
synonym: "regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:2000826 ! regulation of heart morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003206 ! cardiac chamber morphogenesis
relationship: regulates GO:0003206 ! cardiac chamber morphogenesis
created_by: rl
creation_date: 2012-08-06T17:59:11Z

[Term]
id: GO:1901220
name: negative regulation of cardiac chamber morphogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie]
synonym: "down regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "down regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of cardiac chamber morphogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of heart chamber morphogenesis" NARROW [GOC:TermGenie]
synonym: "negative regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003206 ! cardiac chamber morphogenesis
relationship: negatively_regulates GO:0003206 ! cardiac chamber morphogenesis
created_by: rl
creation_date: 2012-08-06T17:59:34Z

[Term]
id: GO:1901221
name: positive regulation of cardiac chamber morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie]
synonym: "activation of cardiac chamber morphogenesis" NARROW [GOC:TermGenie]
synonym: "activation of heart chamber morphogenesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003206 ! cardiac chamber morphogenesis
relationship: positively_regulates GO:0003206 ! cardiac chamber morphogenesis
created_by: rl
creation_date: 2012-08-06T17:59:42Z

[Term]
id: GO:1901246
name: regulation of lung ciliated cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie]
is_a: GO:0030856 ! regulation of epithelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061141 ! lung ciliated cell differentiation
relationship: regulates GO:0061141 ! lung ciliated cell differentiation
created_by: vk
creation_date: 2012-08-08T08:58:34Z

[Term]
id: GO:1901247
name: negative regulation of lung ciliated cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie]
synonym: "down regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of lung ciliated cell differentiation" NARROW [GOC:TermGenie]
is_a: GO:0030857 ! negative regulation of epithelial cell differentiation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1901246 ! regulation of lung ciliated cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061141 ! lung ciliated cell differentiation
relationship: negatively_regulates GO:0061141 ! lung ciliated cell differentiation
created_by: vk
creation_date: 2012-08-08T08:58:58Z

[Term]
id: GO:1901248
name: positive regulation of lung ciliated cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie]
synonym: "activation of lung ciliated cell differentiation" NARROW [GOC:TermGenie]
synonym: "up regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0030858 ! positive regulation of epithelial cell differentiation
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1901246 ! regulation of lung ciliated cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061141 ! lung ciliated cell differentiation
relationship: positively_regulates GO:0061141 ! lung ciliated cell differentiation
created_by: vk
creation_date: 2012-08-08T08:59:05Z

[Term]
id: GO:1901264
name: carbohydrate derivative transport
namespace: biological_process
def: "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:jl, GOC:TermGenie]
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative
relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative
created_by: bf
creation_date: 2012-08-16T14:51:22Z

[Term]
id: GO:1901317
name: regulation of flagellated sperm motility
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie]
synonym: "regulation of sperm motility" BROAD []
synonym: "regulation of sperm movement" BROAD [GOC:TermGenie]
is_a: GO:0060295 ! regulation of cilium movement involved in cell motility
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030317 ! flagellated sperm motility
relationship: regulates GO:0030317 ! flagellated sperm motility
created_by: hjd
creation_date: 2012-08-22T20:50:14Z

[Term]
id: GO:1901318
name: negative regulation of flagellated sperm motility
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie]
synonym: "down regulation of sperm motility" BROAD [GOC:TermGenie]
synonym: "down regulation of sperm movement" BROAD [GOC:TermGenie]
synonym: "down-regulation of sperm motility" BROAD [GOC:TermGenie]
synonym: "down-regulation of sperm movement" BROAD [GOC:TermGenie]
synonym: "downregulation of sperm motility" BROAD [GOC:TermGenie]
synonym: "downregulation of sperm movement" BROAD [GOC:TermGenie]
synonym: "inhibition of sperm motility" NARROW [GOC:TermGenie]
synonym: "inhibition of sperm movement" BROAD [GOC:TermGenie]
synonym: "negative regulation of sperm motility" BROAD []
synonym: "negative regulation of sperm movement" BROAD [GOC:TermGenie]
is_a: GO:0003354 ! negative regulation of cilium movement
is_a: GO:1901317 ! regulation of flagellated sperm motility
is_a: GO:1902020 ! negative regulation of cilium-dependent cell motility
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030317 ! flagellated sperm motility
relationship: negatively_regulates GO:0030317 ! flagellated sperm motility
created_by: hjd
creation_date: 2012-08-22T20:50:35Z

[Term]
id: GO:1901342
name: regulation of vasculature development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vasculature development." [GOC:TermGenie]
synonym: "regulation of vascular system development" RELATED [GOC:TermGenie]
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001944 ! vasculature development
relationship: regulates GO:0001944 ! vasculature development
created_by: bf
creation_date: 2012-09-06T09:16:15Z

[Term]
id: GO:1901343
name: negative regulation of vasculature development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development." [GOC:TermGenie]
synonym: "down regulation of vascular system development" RELATED [GOC:TermGenie]
synonym: "down regulation of vasculature development" EXACT [GOC:TermGenie]
synonym: "down-regulation of vascular system development" RELATED [GOC:TermGenie]
synonym: "down-regulation of vasculature development" EXACT [GOC:TermGenie]
synonym: "downregulation of vascular system development" RELATED [GOC:TermGenie]
synonym: "downregulation of vasculature development" EXACT [GOC:TermGenie]
synonym: "inhibition of vascular system development" RELATED [GOC:TermGenie]
synonym: "inhibition of vasculature development" NARROW [GOC:TermGenie]
synonym: "negative regulation of vascular system development" RELATED [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1901342 ! regulation of vasculature development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001944 ! vasculature development
relationship: negatively_regulates GO:0001944 ! vasculature development
created_by: bf
creation_date: 2012-09-06T09:17:24Z

[Term]
id: GO:1901360
name: organic cyclic compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving organic cyclic compound." [GOC:TermGenie]
synonym: "organic cyclic compound metabolism" EXACT [GOC:TermGenie]
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:33832 ! organic cyclic compound
relationship: has_primary_input_or_output CHEBI:33832 ! organic cyclic compound
created_by: bf
creation_date: 2012-09-14T09:03:51Z

[Term]
id: GO:1901361
name: organic cyclic compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of organic cyclic compound." [GOC:TermGenie]
synonym: "organic cyclic compound breakdown" EXACT [GOC:TermGenie]
synonym: "organic cyclic compound catabolism" EXACT [GOC:TermGenie]
synonym: "organic cyclic compound degradation" EXACT [GOC:TermGenie]
is_a: GO:1901360 ! organic cyclic compound metabolic process
is_a: GO:1901575 ! organic substance catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:33832 ! organic cyclic compound
relationship: has_primary_input CHEBI:33832 ! organic cyclic compound
created_by: bf
creation_date: 2012-09-14T09:05:04Z

[Term]
id: GO:1901362
name: organic cyclic compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of organic cyclic compound." [GOC:TermGenie]
synonym: "organic cyclic compound anabolism" EXACT [GOC:TermGenie]
synonym: "organic cyclic compound biosynthesis" EXACT [GOC:TermGenie]
synonym: "organic cyclic compound formation" EXACT [GOC:TermGenie]
synonym: "organic cyclic compound synthesis" EXACT [GOC:TermGenie]
is_a: GO:1901360 ! organic cyclic compound metabolic process
is_a: GO:1901576 ! organic substance biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:33832 ! organic cyclic compound
relationship: has_primary_output CHEBI:33832 ! organic cyclic compound
created_by: bf
creation_date: 2012-09-14T09:05:22Z

[Term]
id: GO:1901374
name: acetate ester transport
namespace: biological_process
def: "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie]
is_a: GO:0071702 ! organic substance transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:47622 ! acetate ester
relationship: has_primary_input CHEBI:47622 ! acetate ester
created_by: bf
creation_date: 2012-09-28T10:42:13Z

[Term]
id: GO:1901375
name: acetate ester transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of an acetate ester from one side of a membrane to the other." [GOC:TermGenie]
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:47622 ! acetate ester
relationship: has_primary_input CHEBI:47622 ! acetate ester
relationship: part_of GO:1901374 ! acetate ester transport
created_by: bf
creation_date: 2012-09-28T10:47:08Z

[Term]
id: GO:1901382
name: regulation of chorionic trophoblast cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097360 ! chorionic trophoblast cell proliferation
relationship: regulates GO:0097360 ! chorionic trophoblast cell proliferation
created_by: vk
creation_date: 2012-10-01T10:03:13Z

[Term]
id: GO:1901383
name: negative regulation of chorionic trophoblast cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie]
synonym: "down regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie]
synonym: "inhibition of chorionic trophoblast cell proliferation" NARROW [GOC:TermGenie]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097360 ! chorionic trophoblast cell proliferation
relationship: negatively_regulates GO:0097360 ! chorionic trophoblast cell proliferation
created_by: vk
creation_date: 2012-10-01T10:04:23Z

[Term]
id: GO:1901384
name: positive regulation of chorionic trophoblast cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie]
synonym: "activation of chorionic trophoblast cell proliferation" NARROW [GOC:TermGenie]
synonym: "up regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097360 ! chorionic trophoblast cell proliferation
relationship: positively_regulates GO:0097360 ! chorionic trophoblast cell proliferation
created_by: vk
creation_date: 2012-10-01T10:04:41Z

[Term]
id: GO:1901401
name: regulation of tetrapyrrole metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie]
synonym: "regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
is_a: GO:0031323 ! regulation of cellular metabolic process
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0033013 ! tetrapyrrole metabolic process
relationship: regulates GO:0033013 ! tetrapyrrole metabolic process
created_by: tt
creation_date: 2012-10-01T14:34:03Z

[Term]
id: GO:1901402
name: negative regulation of tetrapyrrole metabolic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie]
synonym: "down regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie]
synonym: "down regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole metabolic process" NARROW [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process
is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0033013 ! tetrapyrrole metabolic process
relationship: negatively_regulates GO:0033013 ! tetrapyrrole metabolic process
created_by: tt
creation_date: 2012-10-01T14:35:11Z

[Term]
id: GO:1901403
name: positive regulation of tetrapyrrole metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie]
synonym: "activation of tetrapyrrole metabolic process" NARROW [GOC:TermGenie]
synonym: "activation of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie]
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process
is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0033013 ! tetrapyrrole metabolic process
relationship: positively_regulates GO:0033013 ! tetrapyrrole metabolic process
created_by: tt
creation_date: 2012-10-01T14:35:29Z

[Term]
id: GO:1901404
name: regulation of tetrapyrrole catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie]
synonym: "regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie]
is_a: GO:0031329 ! regulation of cellular catabolic process
is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0033015 ! tetrapyrrole catabolic process
relationship: regulates GO:0033015 ! tetrapyrrole catabolic process
created_by: tt
creation_date: 2012-10-01T14:38:12Z

[Term]
id: GO:1901405
name: negative regulation of tetrapyrrole catabolic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie]
synonym: "down regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "down regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie]
synonym: "down regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole catabolic process" NARROW [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole degradation" EXACT [GOC:TermGenie]
synonym: "negative regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "negative regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie]
is_a: GO:0031330 ! negative regulation of cellular catabolic process
is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process
is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0033015 ! tetrapyrrole catabolic process
relationship: negatively_regulates GO:0033015 ! tetrapyrrole catabolic process
created_by: tt
creation_date: 2012-10-01T14:39:22Z

[Term]
id: GO:1901406
name: positive regulation of tetrapyrrole catabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie]
synonym: "activation of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "activation of tetrapyrrole catabolic process" NARROW [GOC:TermGenie]
synonym: "activation of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "activation of tetrapyrrole degradation" EXACT [GOC:TermGenie]
synonym: "positive regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "positive regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie]
is_a: GO:0031331 ! positive regulation of cellular catabolic process
is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process
is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0033015 ! tetrapyrrole catabolic process
relationship: positively_regulates GO:0033015 ! tetrapyrrole catabolic process
created_by: tt
creation_date: 2012-10-01T14:39:40Z

[Term]
id: GO:1901457
name: regulation of response to acetate
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie]
is_a: GO:0048583 ! regulation of response to stimulus
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010034 ! response to acetate
relationship: regulates GO:0010034 ! response to acetate
created_by: tt
creation_date: 2012-10-02T14:25:06Z

[Term]
id: GO:1901458
name: negative regulation of response to acetate
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie]
synonym: "down regulation of response to acetate" EXACT [GOC:TermGenie]
synonym: "down-regulation of response to acetate" EXACT [GOC:TermGenie]
synonym: "downregulation of response to acetate" EXACT [GOC:TermGenie]
synonym: "inhibition of response to acetate" NARROW [GOC:TermGenie]
is_a: GO:0048585 ! negative regulation of response to stimulus
is_a: GO:1901457 ! regulation of response to acetate
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010034 ! response to acetate
relationship: negatively_regulates GO:0010034 ! response to acetate
created_by: tt
creation_date: 2012-10-02T14:26:15Z

[Term]
id: GO:1901459
name: positive regulation of response to acetate
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie]
synonym: "activation of response to acetate" NARROW [GOC:TermGenie]
synonym: "up regulation of response to acetate" EXACT [GOC:TermGenie]
synonym: "up-regulation of response to acetate" EXACT [GOC:TermGenie]
synonym: "upregulation of response to acetate" EXACT [GOC:TermGenie]
is_a: GO:0048584 ! positive regulation of response to stimulus
is_a: GO:1901457 ! regulation of response to acetate
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010034 ! response to acetate
relationship: positively_regulates GO:0010034 ! response to acetate
created_by: tt
creation_date: 2012-10-02T14:26:34Z

[Term]
id: GO:1901463
name: regulation of tetrapyrrole biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie]
synonym: "regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "regulation of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
is_a: GO:0031326 ! regulation of cellular biosynthetic process
is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0033014 ! tetrapyrrole biosynthetic process
relationship: regulates GO:0033014 ! tetrapyrrole biosynthetic process
created_by: tt
creation_date: 2012-10-02T14:34:14Z

[Term]
id: GO:1901464
name: negative regulation of tetrapyrrole biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie]
synonym: "down regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "down regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down regulation of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "down regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "downregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "inhibition of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
is_a: GO:0031327 ! negative regulation of cellular biosynthetic process
is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process
is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0033014 ! tetrapyrrole biosynthetic process
relationship: negatively_regulates GO:0033014 ! tetrapyrrole biosynthetic process
created_by: tt
creation_date: 2012-10-02T14:35:26Z

[Term]
id: GO:1901465
name: positive regulation of tetrapyrrole biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie]
synonym: "activation of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "activation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "activation of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie]
synonym: "activation of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "activation of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "positive regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "up regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole formation" EXACT [GOC:TermGenie]
synonym: "upregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie]
is_a: GO:0031328 ! positive regulation of cellular biosynthetic process
is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process
is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0033014 ! tetrapyrrole biosynthetic process
relationship: positively_regulates GO:0033014 ! tetrapyrrole biosynthetic process
created_by: tt
creation_date: 2012-10-02T14:35:43Z

[Term]
id: GO:1901505
name: carbohydrate derivative transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of carbohydrate derivative from one side of a membrane to the other." [GOC:pr, GOC:TermGenie]
synonym: "carbohydrate derivative transporter activity" RELATED []
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative
relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative
relationship: part_of GO:1901264 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! carbohydrate derivative transport
created_by: pr
creation_date: 2012-10-17T10:31:22Z

[Term]
id: GO:1901509
name: regulation of endothelial tube morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis." [GOC:dph, GOC:TermGenie]
is_a: GO:1905330 ! regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061154 ! endothelial tube morphogenesis
relationship: regulates GO:0061154 ! endothelial tube morphogenesis
created_by: dph
creation_date: 2012-10-17T14:30:40Z

[Term]
id: GO:1901532
name: regulation of hematopoietic progenitor cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie]
synonym: "regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "regulation of hemopoietic progenitor cell differentiation" EXACT []
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002244 ! hematopoietic progenitor cell differentiation
relationship: regulates GO:0002244 ! hematopoietic progenitor cell differentiation
created_by: vk
creation_date: 2012-10-24T11:23:01Z

[Term]
id: GO:1901533
name: negative regulation of hematopoietic progenitor cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie]
synonym: "down regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie]
synonym: "down regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie]
synonym: "down-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie]
synonym: "downregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie]
synonym: "inhibition of hemopoietic progenitor cell differentiation" NARROW [GOC:TermGenie]
synonym: "negative regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "negative regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "negative regulation of hemopoietic progenitor cell differentiation" EXACT []
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation
relationship: negatively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation
created_by: vk
creation_date: 2012-10-24T11:23:06Z

[Term]
id: GO:1901534
name: positive regulation of hematopoietic progenitor cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie]
synonym: "activation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "activation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "activation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie]
synonym: "activation of hemopoietic progenitor cell differentiation" NARROW [GOC:TermGenie]
synonym: "positive regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "positive regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "positive regulation of hemopoietic progenitor cell differentiation" EXACT []
synonym: "up regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie]
synonym: "up regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie]
synonym: "up-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie]
synonym: "upregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation
relationship: positively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation
created_by: vk
creation_date: 2012-10-24T11:23:14Z

[Term]
id: GO:1901550
name: regulation of endothelial cell development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579]
is_a: GO:0045601 ! regulation of endothelial cell differentiation
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001885 ! endothelial cell development
relationship: regulates GO:0001885 ! endothelial cell development
created_by: pr
creation_date: 2012-10-30T12:59:50Z

[Term]
id: GO:1901551
name: negative regulation of endothelial cell development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579]
synonym: "down regulation of endothelial cell development" EXACT [GOC:TermGenie]
synonym: "down-regulation of endothelial cell development" EXACT [GOC:TermGenie]
synonym: "downregulation of endothelial cell development" EXACT [GOC:TermGenie]
synonym: "inhibition of endothelial cell development" NARROW [GOC:TermGenie]
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0045602 ! negative regulation of endothelial cell differentiation
is_a: GO:1901550 ! regulation of endothelial cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001885 ! endothelial cell development
relationship: negatively_regulates GO:0001885 ! endothelial cell development
created_by: pr
creation_date: 2012-10-30T12:59:54Z

[Term]
id: GO:1901552
name: positive regulation of endothelial cell development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579]
synonym: "activation of endothelial cell development" NARROW [GOC:TermGenie]
synonym: "up regulation of endothelial cell development" EXACT [GOC:TermGenie]
synonym: "up-regulation of endothelial cell development" EXACT [GOC:TermGenie]
synonym: "upregulation of endothelial cell development" EXACT [GOC:TermGenie]
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:1901550 ! regulation of endothelial cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001885 ! endothelial cell development
relationship: positively_regulates GO:0001885 ! endothelial cell development
created_by: pr
creation_date: 2012-10-30T12:59:58Z

[Term]
id: GO:1901564
name: organonitrogen compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving organonitrogen compound." [GOC:pr, GOC:TermGenie]
subset: gocheck_do_not_annotate
synonym: "organonitrogen compound metabolism" EXACT [GOC:TermGenie]
is_a: GO:0006807 ! nitrogen compound metabolic process
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:35352 ! organonitrogen compound
relationship: has_primary_input_or_output CHEBI:35352 ! organonitrogen compound
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI
created_by: pr
creation_date: 2012-11-04T15:17:52Z

[Term]
id: GO:1901565
name: organonitrogen compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of organonitrogen compound." [GOC:pr, GOC:TermGenie]
synonym: "organonitrogen compound breakdown" EXACT [GOC:TermGenie]
synonym: "organonitrogen compound catabolism" EXACT [GOC:TermGenie]
synonym: "organonitrogen compound degradation" EXACT [GOC:TermGenie]
is_a: GO:1901564 ! organonitrogen compound metabolic process
is_a: GO:1901575 ! organic substance catabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:35352 ! organonitrogen compound
relationship: has_primary_input CHEBI:35352 ! organonitrogen compound
created_by: pr
creation_date: 2012-11-04T15:17:56Z

[Term]
id: GO:1901566
name: organonitrogen compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of organonitrogen compound." [GOC:pr, GOC:TermGenie]
synonym: "organonitrogen compound anabolism" EXACT [GOC:TermGenie]
synonym: "organonitrogen compound biosynthesis" EXACT [GOC:TermGenie]
synonym: "organonitrogen compound formation" EXACT [GOC:TermGenie]
synonym: "organonitrogen compound synthesis" EXACT [GOC:TermGenie]
is_a: GO:1901564 ! organonitrogen compound metabolic process
is_a: GO:1901576 ! organic substance biosynthetic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:35352 ! organonitrogen compound
relationship: has_primary_output CHEBI:35352 ! organonitrogen compound
created_by: pr
creation_date: 2012-11-04T15:18:00Z

[Term]
id: GO:1901575
name: organic substance catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie]
synonym: "organic molecular entity breakdown" EXACT [GOC:TermGenie]
synonym: "organic molecular entity catabolic process" EXACT []
synonym: "organic molecular entity catabolism" EXACT [GOC:TermGenie]
synonym: "organic molecular entity degradation" EXACT [GOC:TermGenie]
synonym: "organic substance breakdown" EXACT []
synonym: "organic substance catabolism" EXACT []
synonym: "organic substance degradation" EXACT []
is_a: GO:0009056 ! catabolic process
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:50860 ! organic molecular entity
relationship: has_primary_input CHEBI:50860 ! organic molecular entity
created_by: pr
creation_date: 2012-11-05T11:04:36Z

[Term]
id: GO:1901576
name: organic substance biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie]
synonym: "organic molecular entity anabolism" EXACT [GOC:TermGenie]
synonym: "organic molecular entity biosynthesis" EXACT [GOC:TermGenie]
synonym: "organic molecular entity biosynthetic process" EXACT []
synonym: "organic molecular entity formation" EXACT [GOC:TermGenie]
synonym: "organic molecular entity synthesis" EXACT [GOC:TermGenie]
synonym: "organic substance anabolism" EXACT []
synonym: "organic substance biosynthesis" EXACT []
synonym: "organic substance formation" EXACT []
synonym: "organic substance synthesis" EXACT []
is_a: GO:0009058 ! biosynthetic process
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:50860 ! organic molecular entity
relationship: has_primary_output CHEBI:50860 ! organic molecular entity
created_by: pr
creation_date: 2012-11-05T11:04:40Z

[Term]
id: GO:1901605
name: alpha-amino acid metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving an alpha-amino acid." [GOC:TermGenie]
synonym: "alpha-amino acid metabolism" EXACT [GOC:TermGenie]
is_a: GO:0006520 ! amino acid metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:78608 ! alpha-amino acid zwitterion
relationship: has_primary_input_or_output CHEBI:78608 ! alpha-amino acid zwitterion
created_by: tb
creation_date: 2012-11-08T17:39:50Z

[Term]
id: GO:1901606
name: alpha-amino acid catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid." [GOC:TermGenie]
synonym: "alpha-amino acid breakdown" EXACT [GOC:TermGenie]
synonym: "alpha-amino acid catabolism" EXACT [GOC:TermGenie]
synonym: "alpha-amino acid degradation" EXACT [GOC:TermGenie]
is_a: GO:1901575 ! organic substance catabolic process
is_a: GO:1901605 ! alpha-amino acid metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:78608 ! alpha-amino acid zwitterion
relationship: has_primary_input CHEBI:78608 ! alpha-amino acid zwitterion
created_by: tb
creation_date: 2012-11-08T17:39:54Z

[Term]
id: GO:1901607
name: alpha-amino acid biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of an alpha-amino acid." [GOC:TermGenie]
synonym: "alpha-amino acid anabolism" EXACT [GOC:TermGenie]
synonym: "alpha-amino acid biosynthesis" EXACT [GOC:TermGenie]
synonym: "alpha-amino acid formation" EXACT [GOC:TermGenie]
synonym: "alpha-amino acid synthesis" EXACT [GOC:TermGenie]
is_a: GO:1901576 ! organic substance biosynthetic process
is_a: GO:1901605 ! alpha-amino acid metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:78608 ! alpha-amino acid zwitterion
relationship: has_primary_output CHEBI:78608 ! alpha-amino acid zwitterion
created_by: tb
creation_date: 2012-11-08T17:39:58Z

[Term]
id: GO:1901608
name: regulation of vesicle transport along microtubule
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie]
synonym: "regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
is_a: GO:1902513 ! regulation of organelle transport along microtubule
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0047496 ! vesicle transport along microtubule
relationship: regulates GO:0047496 ! vesicle transport along microtubule
created_by: hjd
creation_date: 2012-11-08T21:49:44Z

[Term]
id: GO:1901609
name: negative regulation of vesicle transport along microtubule
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie]
synonym: "down regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
synonym: "down regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie]
synonym: "down-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
synonym: "down-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie]
synonym: "downregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
synonym: "downregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie]
synonym: "inhibition of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
synonym: "inhibition of vesicle transport along microtubule" NARROW [GOC:TermGenie]
synonym: "negative regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
is_a: GO:0032387 ! negative regulation of intracellular transport
is_a: GO:1901608 ! regulation of vesicle transport along microtubule
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0047496 ! vesicle transport along microtubule
relationship: negatively_regulates GO:0047496 ! vesicle transport along microtubule
created_by: hjd
creation_date: 2012-11-08T21:49:48Z

[Term]
id: GO:1901610
name: positive regulation of vesicle transport along microtubule
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie]
synonym: "activation of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
synonym: "activation of vesicle transport along microtubule" NARROW [GOC:TermGenie]
synonym: "positive regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
synonym: "up regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
synonym: "up regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie]
synonym: "up-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
synonym: "up-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie]
synonym: "upregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie]
synonym: "upregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie]
is_a: GO:0032388 ! positive regulation of intracellular transport
is_a: GO:1901608 ! regulation of vesicle transport along microtubule
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0047496 ! vesicle transport along microtubule
relationship: positively_regulates GO:0047496 ! vesicle transport along microtubule
created_by: hjd
creation_date: 2012-11-08T21:49:53Z

[Term]
id: GO:1901615
name: organic hydroxy compound metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving organic hydroxy compound." [GOC:pr, GOC:TermGenie]
synonym: "organic hydroxy compound metabolism" EXACT [GOC:TermGenie]
is_a: GO:0071704 ! organic substance metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:33822 ! organic hydroxy compound
relationship: has_primary_input_or_output CHEBI:33822 ! organic hydroxy compound
created_by: pr
creation_date: 2012-11-13T12:54:27Z

[Term]
id: GO:1901616
name: organic hydroxy compound catabolic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound." [GOC:pr, GOC:TermGenie]
synonym: "organic hydroxy compound breakdown" EXACT [GOC:TermGenie]
synonym: "organic hydroxy compound catabolism" EXACT [GOC:TermGenie]
synonym: "organic hydroxy compound degradation" EXACT [GOC:TermGenie]
is_a: GO:1901575 ! organic substance catabolic process
is_a: GO:1901615 ! organic hydroxy compound metabolic process
intersection_of: GO:0009056 ! catabolic process
intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound
relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound
created_by: pr
creation_date: 2012-11-13T12:54:31Z

[Term]
id: GO:1901617
name: organic hydroxy compound biosynthetic process
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of organic hydroxy compound." [GOC:pr, GOC:TermGenie]
synonym: "organic hydroxy compound anabolism" EXACT [GOC:TermGenie]
synonym: "organic hydroxy compound biosynthesis" EXACT [GOC:TermGenie]
synonym: "organic hydroxy compound formation" EXACT [GOC:TermGenie]
synonym: "organic hydroxy compound synthesis" EXACT [GOC:TermGenie]
is_a: GO:1901576 ! organic substance biosynthetic process
is_a: GO:1901615 ! organic hydroxy compound metabolic process
intersection_of: GO:0009058 ! biosynthetic process
intersection_of: has_primary_output CHEBI:33822 ! organic hydroxy compound
relationship: has_primary_output CHEBI:33822 ! organic hydroxy compound
created_by: pr
creation_date: 2012-11-13T12:54:36Z

[Term]
id: GO:1901618
name: organic hydroxy compound transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of organic hydroxy compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie]
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound
relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound
created_by: pr
creation_date: 2012-11-13T12:59:01Z

[Term]
id: GO:1901652
name: response to peptide
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." [GOC:pr, GOC:TermGenie]
is_a: GO:0010243 ! response to organonitrogen compound
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:16670 ! peptide
relationship: has_primary_input CHEBI:16670 ! peptide
created_by: pr
creation_date: 2012-11-20T09:45:15Z

[Term]
id: GO:1901654
name: response to ketone
namespace: biological_process
alt_id: GO:1990369
def: "A response that results in a state of tolerance to ketone." [GOC:mengo_curators, PMID:23356676]
synonym: "process resulting in tolerance to ketone" NARROW []
is_a: GO:0010033 ! response to organic substance
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:17087 ! ketone
relationship: has_primary_input CHEBI:17087 ! ketone
created_by: pr
creation_date: 2012-11-20T10:55:47Z

[Term]
id: GO:1901682
name: sulfur compound transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of a sulfur compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie]
synonym: "sulfur molecular entity transmembrane transporter activity" EXACT []
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity
relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity
created_by: pr
creation_date: 2012-11-26T20:45:29Z

[Term]
id: GO:1901692
name: regulation of compound eye retinal cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768]
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1990010 ! compound eye retinal cell apoptotic process
relationship: regulates GO:1990010 ! compound eye retinal cell apoptotic process
created_by: pr
creation_date: 2012-12-12T10:28:35Z

[Term]
id: GO:1901693
name: negative regulation of compound eye retinal cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768]
synonym: "down regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "inhibition of compound eye retinal cell apoptotic process" NARROW [GOC:TermGenie]
is_a: GO:0043066 ! negative regulation of apoptotic process
is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1990010 ! compound eye retinal cell apoptotic process
relationship: negatively_regulates GO:1990010 ! compound eye retinal cell apoptotic process
created_by: pr
creation_date: 2012-12-12T10:28:40Z

[Term]
id: GO:1901694
name: positive regulation of compound eye retinal cell apoptotic process
namespace: biological_process
alt_id: GO:0046675
def: "Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768]
synonym: "activation of compound eye retinal cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "induction of compound eye retinal cell programmed cell death" RELATED []
synonym: "up regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0043065 ! positive regulation of apoptotic process
is_a: GO:0046672 ! positive regulation of compound eye retinal cell programmed cell death
is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1990010 ! compound eye retinal cell apoptotic process
relationship: positively_regulates GO:1990010 ! compound eye retinal cell apoptotic process
created_by: pr
creation_date: 2012-12-12T10:28:45Z

[Term]
id: GO:1901698
name: response to nitrogen compound
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." [GOC:pr, GOC:TermGenie]
synonym: "response to nitrogen molecular entity" EXACT []
is_a: GO:0042221 ! response to chemical
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:51143 ! nitrogen molecular entity
relationship: has_primary_input CHEBI:51143 ! nitrogen molecular entity
created_by: pr
creation_date: 2012-12-13T15:06:08Z

[Term]
id: GO:1901700
name: response to oxygen-containing compound
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." [GOC:pr, GOC:TermGenie]
synonym: "response to oxygen molecular entity" EXACT []
is_a: GO:0042221 ! response to chemical
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:25806 ! oxygen molecular entity
relationship: has_primary_input CHEBI:25806 ! oxygen molecular entity
created_by: pr
creation_date: 2012-12-13T15:11:37Z

[Term]
id: GO:1901702
name: salt transmembrane transporter activity
namespace: molecular_function
def: "Enables the transfer of salt from one side of a membrane to the other." [GOC:pr, GOC:TermGenie]
is_a: GO:0022857 ! transmembrane transporter activity
intersection_of: GO:0022857 ! transmembrane transporter activity
intersection_of: has_primary_input CHEBI:24866 ! salt
relationship: has_primary_input CHEBI:24866 ! salt
created_by: pr
creation_date: 2012-12-13T15:14:47Z

[Term]
id: GO:1901706
name: mesenchymal cell differentiation involved in bone development
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state." [GOC:hjd, GOC:TermGenie, PMID:21571217]
is_a: GO:0048762 ! mesenchymal cell differentiation
intersection_of: GO:0048762 ! mesenchymal cell differentiation
intersection_of: part_of GO:0060348 ! bone development
relationship: part_of GO:0060348 ! bone development
created_by: hjd
creation_date: 2012-12-14T16:04:16Z

[Term]
id: GO:1901722
name: regulation of cell proliferation involved in kidney development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072111 ! cell proliferation involved in kidney development
relationship: regulates GO:0072111 ! cell proliferation involved in kidney development
created_by: krc
creation_date: 2012-12-27T19:30:31Z

[Term]
id: GO:1901723
name: negative regulation of cell proliferation involved in kidney development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616]
synonym: "down regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie]
synonym: "down-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie]
synonym: "downregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie]
synonym: "inhibition of cell proliferation involved in kidney development" NARROW [GOC:TermGenie]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072111 ! cell proliferation involved in kidney development
relationship: negatively_regulates GO:0072111 ! cell proliferation involved in kidney development
created_by: krc
creation_date: 2012-12-27T19:30:35Z

[Term]
id: GO:1901724
name: positive regulation of cell proliferation involved in kidney development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616]
synonym: "activation of cell proliferation involved in kidney development" NARROW [GOC:TermGenie]
synonym: "up regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie]
synonym: "up-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie]
synonym: "upregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072111 ! cell proliferation involved in kidney development
relationship: positively_regulates GO:0072111 ! cell proliferation involved in kidney development
created_by: krc
creation_date: 2012-12-27T19:30:40Z

[Term]
id: GO:1901861
name: regulation of muscle tissue development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060537 ! muscle tissue development
relationship: regulates GO:0060537 ! muscle tissue development
created_by: yaf
creation_date: 2013-02-01T10:30:47Z

[Term]
id: GO:1901862
name: negative regulation of muscle tissue development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719]
synonym: "down regulation of muscle tissue development" EXACT [GOC:TermGenie]
synonym: "down-regulation of muscle tissue development" EXACT [GOC:TermGenie]
synonym: "downregulation of muscle tissue development" EXACT [GOC:TermGenie]
synonym: "inhibition of muscle tissue development" NARROW [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:1901861 ! regulation of muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060537 ! muscle tissue development
relationship: negatively_regulates GO:0060537 ! muscle tissue development
created_by: yaf
creation_date: 2013-02-01T10:30:52Z

[Term]
id: GO:1901863
name: positive regulation of muscle tissue development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719]
synonym: "activation of muscle tissue development" NARROW [GOC:TermGenie]
synonym: "up regulation of muscle tissue development" EXACT [GOC:TermGenie]
synonym: "up-regulation of muscle tissue development" EXACT [GOC:TermGenie]
synonym: "upregulation of muscle tissue development" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:1901861 ! regulation of muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060537 ! muscle tissue development
relationship: positively_regulates GO:0060537 ! muscle tissue development
created_by: yaf
creation_date: 2013-02-01T10:30:57Z

[Term]
id: GO:1901879
name: regulation of protein depolymerization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137]
synonym: "regulation of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "regulation of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "regulation of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "regulation of protein polymer degradation" EXACT [GOC:TermGenie]
is_a: GO:0043244 ! regulation of protein-containing complex disassembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051261 ! protein depolymerization
relationship: regulates GO:0051261 ! protein depolymerization
created_by: rl
creation_date: 2013-02-06T13:57:23Z

[Term]
id: GO:1901880
name: negative regulation of protein depolymerization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137]
synonym: "down regulation of protein depolymerization" EXACT [GOC:TermGenie]
synonym: "down regulation of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "down regulation of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "down regulation of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of protein polymer degradation" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein depolymerization" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein polymer degradation" EXACT [GOC:TermGenie]
synonym: "downregulation of protein depolymerization" EXACT [GOC:TermGenie]
synonym: "downregulation of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "downregulation of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "downregulation of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of protein polymer degradation" EXACT [GOC:TermGenie]
synonym: "inhibition of protein depolymerization" NARROW [GOC:TermGenie]
synonym: "inhibition of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "inhibition of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "inhibition of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "inhibition of protein polymer degradation" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein polymer degradation" EXACT [GOC:TermGenie]
is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly
is_a: GO:1901879 ! regulation of protein depolymerization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051261 ! protein depolymerization
relationship: negatively_regulates GO:0051261 ! protein depolymerization
created_by: rl
creation_date: 2013-02-06T13:57:28Z

[Term]
id: GO:1901881
name: positive regulation of protein depolymerization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137]
synonym: "activation of protein depolymerization" NARROW [GOC:TermGenie]
synonym: "activation of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "activation of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "activation of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "activation of protein polymer degradation" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein polymer degradation" EXACT [GOC:TermGenie]
synonym: "up regulation of protein depolymerization" EXACT [GOC:TermGenie]
synonym: "up regulation of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "up regulation of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "up regulation of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of protein polymer degradation" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein depolymerization" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein polymer degradation" EXACT [GOC:TermGenie]
synonym: "upregulation of protein depolymerization" EXACT [GOC:TermGenie]
synonym: "upregulation of protein polymer breakdown" EXACT [GOC:TermGenie]
synonym: "upregulation of protein polymer catabolic process" EXACT [GOC:TermGenie]
synonym: "upregulation of protein polymer catabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of protein polymer degradation" EXACT [GOC:TermGenie]
is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly
is_a: GO:1901879 ! regulation of protein depolymerization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051261 ! protein depolymerization
relationship: positively_regulates GO:0051261 ! protein depolymerization
created_by: rl
creation_date: 2013-02-06T13:57:32Z

[Term]
id: GO:1901888
name: regulation of cell junction assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell junction assembly." [GOC:TermGenie]
is_a: GO:0044087 ! regulation of cellular component biogenesis
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0034329 ! cell junction assembly
relationship: regulates GO:0034329 ! cell junction assembly
created_by: tb
creation_date: 2013-02-06T19:40:32Z

[Term]
id: GO:1901889
name: negative regulation of cell junction assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly." [GOC:TermGenie]
synonym: "down regulation of cell junction assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of cell junction assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of cell junction assembly" EXACT [GOC:TermGenie]
synonym: "inhibition of cell junction assembly" NARROW [GOC:TermGenie]
is_a: GO:0051129 ! negative regulation of cellular component organization
is_a: GO:1901888 ! regulation of cell junction assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0034329 ! cell junction assembly
relationship: negatively_regulates GO:0034329 ! cell junction assembly
created_by: tb
creation_date: 2013-02-06T19:40:41Z

[Term]
id: GO:1901890
name: positive regulation of cell junction assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell junction assembly." [GOC:TermGenie]
synonym: "activation of cell junction assembly" NARROW [GOC:TermGenie]
synonym: "up regulation of cell junction assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of cell junction assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of cell junction assembly" EXACT [GOC:TermGenie]
is_a: GO:0044089 ! positive regulation of cellular component biogenesis
is_a: GO:0051130 ! positive regulation of cellular component organization
is_a: GO:1901888 ! regulation of cell junction assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0034329 ! cell junction assembly
relationship: positively_regulates GO:0034329 ! cell junction assembly
created_by: tb
creation_date: 2013-02-06T19:40:46Z

[Term]
id: GO:1901963
name: regulation of cell proliferation involved in outflow tract morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760]
is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis
relationship: regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis
created_by: dph
creation_date: 2013-02-20T20:30:26Z

[Term]
id: GO:1901964
name: positive regulation of cell proliferation involved in outflow tract morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760]
synonym: "activation of cell proliferation involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:1901963 ! regulation of cell proliferation involved in outflow tract morphogenesis
is_a: GO:2000138 ! positive regulation of cell proliferation involved in heart morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis
relationship: positively_regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis
created_by: dph
creation_date: 2013-02-20T20:30:31Z

[Term]
id: GO:1902017
name: regulation of cilium assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545]
synonym: "regulation of ciliogenesis" EXACT [GOC:TermGenie]
synonym: "regulation of cilium biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly
is_a: GO:1902115 ! regulation of organelle assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060271 ! cilium assembly
relationship: regulates GO:0060271 ! cilium assembly
created_by: dph
creation_date: 2013-03-26T18:10:51Z

[Term]
id: GO:1902018
name: negative regulation of cilium assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545]
synonym: "down regulation of ciliogenesis" EXACT [GOC:TermGenie]
synonym: "down regulation of cilium assembly" EXACT [GOC:TermGenie]
synonym: "down regulation of cilium biogenesis" RELATED [GOC:TermGenie]
synonym: "down-regulation of ciliogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of cilium assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of cilium biogenesis" RELATED [GOC:TermGenie]
synonym: "downregulation of ciliogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of cilium assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of cilium biogenesis" RELATED [GOC:TermGenie]
synonym: "inhibition of ciliogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of cilium assembly" NARROW [GOC:TermGenie]
synonym: "inhibition of cilium biogenesis" RELATED [GOC:TermGenie]
synonym: "negative regulation of ciliogenesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of cilium biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly
is_a: GO:1902017 ! regulation of cilium assembly
is_a: GO:1902116 ! negative regulation of organelle assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060271 ! cilium assembly
relationship: negatively_regulates GO:0060271 ! cilium assembly
created_by: dph
creation_date: 2013-03-26T18:10:56Z

[Term]
id: GO:1902019
name: regulation of cilium-dependent cell motility
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie]
synonym: "regulation of ciliary cell motility" RELATED []
synonym: "regulation of cilium cell motility" EXACT []
is_a: GO:2000145 ! regulation of cell motility
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060285 ! cilium-dependent cell motility
relationship: regulates GO:0060285 ! cilium-dependent cell motility
created_by: jl
creation_date: 2013-03-27T14:42:38Z

[Term]
id: GO:1902020
name: negative regulation of cilium-dependent cell motility
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie]
synonym: "down regulation of ciliary cell motility" EXACT [GOC:TermGenie]
synonym: "down-regulation of ciliary cell motility" EXACT [GOC:TermGenie]
synonym: "downregulation of ciliary cell motility" EXACT [GOC:TermGenie]
synonym: "inhibition of ciliary cell motility" NARROW [GOC:TermGenie]
synonym: "negative regulation of ciliary cell motility" RELATED []
synonym: "negative regulation of cilium cell motility" EXACT []
is_a: GO:1902019 ! regulation of cilium-dependent cell motility
is_a: GO:2000146 ! negative regulation of cell motility
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060285 ! cilium-dependent cell motility
relationship: negatively_regulates GO:0060285 ! cilium-dependent cell motility
created_by: jl
creation_date: 2013-03-27T14:42:42Z

[Term]
id: GO:1902033
name: regulation of hematopoietic stem cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623]
synonym: "regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0072091 ! regulation of stem cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0071425 ! hematopoietic stem cell proliferation
relationship: regulates GO:0071425 ! hematopoietic stem cell proliferation
created_by: ss
creation_date: 2013-04-02T05:13:19Z

[Term]
id: GO:1902034
name: negative regulation of hematopoietic stem cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623]
synonym: "down regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "down regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "inhibition of hematopoietic stem cell proliferation" NARROW [GOC:TermGenie]
synonym: "inhibition of hemopoietic stem cell proliferation" NARROW [GOC:TermGenie]
synonym: "negative regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation
is_a: GO:1903707 ! negative regulation of hemopoiesis
is_a: GO:2000647 ! negative regulation of stem cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0071425 ! hematopoietic stem cell proliferation
relationship: negatively_regulates GO:0071425 ! hematopoietic stem cell proliferation
created_by: ss
creation_date: 2013-04-02T05:13:24Z

[Term]
id: GO:1902035
name: positive regulation of hematopoietic stem cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623]
synonym: "activation of hematopoietic stem cell proliferation" NARROW [GOC:TermGenie]
synonym: "activation of hemopoietic stem cell proliferation" NARROW [GOC:TermGenie]
synonym: "positive regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation
is_a: GO:2000648 ! positive regulation of stem cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0071425 ! hematopoietic stem cell proliferation
relationship: positively_regulates GO:0071425 ! hematopoietic stem cell proliferation
created_by: ss
creation_date: 2013-04-02T05:13:31Z

[Term]
id: GO:1902036
name: regulation of hematopoietic stem cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623]
synonym: "regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation
is_a: GO:2000736 ! regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060218 ! hematopoietic stem cell differentiation
relationship: regulates GO:0060218 ! hematopoietic stem cell differentiation
created_by: ss
creation_date: 2013-04-02T05:19:09Z

[Term]
id: GO:1902037
name: negative regulation of hematopoietic stem cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623]
synonym: "down regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of haematopoietic stem cell differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of haemopoietic stem cell differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of hematopoietic stem cell differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of hemopoietic stem cell differentiation" NARROW [GOC:TermGenie]
synonym: "negative regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "negative regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "negative regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation
is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation
is_a: GO:2000737 ! negative regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060218 ! hematopoietic stem cell differentiation
relationship: negatively_regulates GO:0060218 ! hematopoietic stem cell differentiation
created_by: ss
creation_date: 2013-04-02T05:19:14Z

[Term]
id: GO:1902038
name: positive regulation of hematopoietic stem cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623]
synonym: "activation of haematopoietic stem cell differentiation" NARROW [GOC:TermGenie]
synonym: "activation of haemopoietic stem cell differentiation" NARROW [GOC:TermGenie]
synonym: "activation of hematopoietic stem cell differentiation" NARROW [GOC:TermGenie]
synonym: "activation of hemopoietic stem cell differentiation" NARROW [GOC:TermGenie]
synonym: "positive regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "positive regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "positive regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation
is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation
is_a: GO:2000738 ! positive regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060218 ! hematopoietic stem cell differentiation
relationship: positively_regulates GO:0060218 ! hematopoietic stem cell differentiation
created_by: ss
creation_date: 2013-04-02T05:19:19Z

[Term]
id: GO:1902074
name: response to salt
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." [GOC:mls, GOC:TermGenie, PMID:16666921]
synonym: "response to salinity" NARROW [GOC:mls]
is_a: GO:0042221 ! response to chemical
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:24866 ! salt
relationship: has_primary_input CHEBI:24866 ! salt
created_by: mls
creation_date: 2013-04-22T15:41:57Z

[Term]
id: GO:1902093
name: positive regulation of flagellated sperm motility
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:jh2, GOC:krc, GOC:TermGenie, PMID:7513657]
synonym: "activation of sperm motility" NARROW [GOC:TermGenie]
synonym: "activation of sperm movement" BROAD [GOC:TermGenie]
synonym: "positive regulation of sperm motility" BROAD []
synonym: "positive regulation of sperm movement" BROAD [GOC:TermGenie]
synonym: "up regulation of sperm motility" BROAD [GOC:TermGenie]
synonym: "up regulation of sperm movement" BROAD [GOC:TermGenie]
synonym: "up-regulation of sperm motility" BROAD [GOC:TermGenie]
synonym: "up-regulation of sperm movement" BROAD [GOC:TermGenie]
synonym: "upregulation of sperm motility" BROAD [GOC:TermGenie]
synonym: "upregulation of sperm movement" BROAD [GOC:TermGenie]
is_a: GO:0003353 ! positive regulation of cilium movement
is_a: GO:1901317 ! regulation of flagellated sperm motility
is_a: GO:2000155 ! positive regulation of cilium-dependent cell motility
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030317 ! flagellated sperm motility
relationship: positively_regulates GO:0030317 ! flagellated sperm motility
created_by: bf
creation_date: 2013-04-29T09:15:25Z

[Term]
id: GO:1902105
name: regulation of leukocyte differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie]
synonym: "regulation of immune cell differentiation" EXACT [GOC:TermGenie]
synonym: "regulation of leucocyte differentiation" EXACT [GOC:TermGenie]
is_a: GO:1903706 ! regulation of hemopoiesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002521 ! leukocyte differentiation
relationship: regulates GO:0002521 ! leukocyte differentiation
created_by: pr
creation_date: 2013-05-02T17:32:42Z

[Term]
id: GO:1902106
name: negative regulation of leukocyte differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie]
synonym: "down regulation of immune cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of leucocyte differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of leukocyte differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of immune cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of leucocyte differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of leukocyte differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of immune cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of leucocyte differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of leukocyte differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of immune cell differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of leucocyte differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of leukocyte differentiation" NARROW [GOC:TermGenie]
synonym: "negative regulation of immune cell differentiation" EXACT [GOC:TermGenie]
synonym: "negative regulation of leucocyte differentiation" EXACT [GOC:TermGenie]
is_a: GO:1902105 ! regulation of leukocyte differentiation
is_a: GO:1903707 ! negative regulation of hemopoiesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002521 ! leukocyte differentiation
relationship: negatively_regulates GO:0002521 ! leukocyte differentiation
created_by: pr
creation_date: 2013-05-02T17:32:47Z

[Term]
id: GO:1902107
name: positive regulation of leukocyte differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie]
synonym: "activation of immune cell differentiation" NARROW [GOC:TermGenie]
synonym: "activation of leucocyte differentiation" NARROW [GOC:TermGenie]
synonym: "activation of leukocyte differentiation" NARROW [GOC:TermGenie]
synonym: "positive regulation of immune cell differentiation" EXACT [GOC:TermGenie]
synonym: "positive regulation of leucocyte differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of immune cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of leucocyte differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of leukocyte differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of immune cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of leucocyte differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of leukocyte differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of immune cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of leucocyte differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of leukocyte differentiation" EXACT [GOC:TermGenie]
is_a: GO:1902105 ! regulation of leukocyte differentiation
is_a: GO:1903708 ! positive regulation of hemopoiesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002521 ! leukocyte differentiation
relationship: positively_regulates GO:0002521 ! leukocyte differentiation
created_by: pr
creation_date: 2013-05-02T17:32:52Z

[Term]
id: GO:1902115
name: regulation of organelle assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie]
is_a: GO:0033043 ! regulation of organelle organization
is_a: GO:0044087 ! regulation of cellular component biogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0070925 ! organelle assembly
relationship: regulates GO:0070925 ! organelle assembly
created_by: pr
creation_date: 2013-05-14T09:43:21Z

[Term]
id: GO:1902116
name: negative regulation of organelle assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie]
synonym: "down regulation of organelle assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of organelle assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of organelle assembly" EXACT [GOC:TermGenie]
synonym: "inhibition of organelle assembly" NARROW [GOC:TermGenie]
is_a: GO:0010639 ! negative regulation of organelle organization
is_a: GO:1902115 ! regulation of organelle assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0070925 ! organelle assembly
relationship: negatively_regulates GO:0070925 ! organelle assembly
created_by: pr
creation_date: 2013-05-14T09:43:31Z

[Term]
id: GO:1902117
name: positive regulation of organelle assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie]
synonym: "activation of organelle assembly" NARROW [GOC:TermGenie]
synonym: "up regulation of organelle assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of organelle assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of organelle assembly" EXACT [GOC:TermGenie]
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:0044089 ! positive regulation of cellular component biogenesis
is_a: GO:1902115 ! regulation of organelle assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0070925 ! organelle assembly
relationship: positively_regulates GO:0070925 ! organelle assembly
created_by: pr
creation_date: 2013-05-14T09:43:36Z

[Term]
id: GO:1902217
name: erythrocyte apoptotic process
namespace: biological_process
def: "Any apoptotic process in an erythrocyte." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084]
synonym: "erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "RBC apoptotic process" EXACT [GOC:TermGenie]
synonym: "red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "red blood cell apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0033028 ! myeloid cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000232 ! erythrocyte
relationship: occurs_in CL:0000232 ! erythrocyte
property_value: RO:0002161 NCBITaxon:4751
created_by: rl
creation_date: 2013-06-13T10:02:29Z

[Term]
id: GO:1902250
name: regulation of erythrocyte apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084]
synonym: "regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of RBC apoptotic process" EXACT [GOC:TermGenie]
synonym: "regulation of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0033032 ! regulation of myeloid cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1902217 ! erythrocyte apoptotic process
relationship: regulates GO:1902217 ! erythrocyte apoptotic process
created_by: rl
creation_date: 2013-06-20T19:30:53Z

[Term]
id: GO:1902251
name: negative regulation of erythrocyte apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084]
synonym: "down regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "down regulation of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of RBC apoptotic process" EXACT [GOC:TermGenie]
synonym: "down regulation of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of RBC apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of RBC apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "inhibition of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of erythrocyte apoptotic process" NARROW [GOC:TermGenie]
synonym: "inhibition of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of RBC apoptotic process" NARROW [GOC:TermGenie]
synonym: "inhibition of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of red blood cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "negative regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of RBC apoptotic process" EXACT [GOC:TermGenie]
synonym: "negative regulation of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0033033 ! negative regulation of myeloid cell apoptotic process
is_a: GO:1902250 ! regulation of erythrocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1902217 ! erythrocyte apoptotic process
relationship: negatively_regulates GO:1902217 ! erythrocyte apoptotic process
property_value: RO:0002161 NCBITaxon:4751
created_by: rl
creation_date: 2013-06-20T19:30:59Z

[Term]
id: GO:1902252
name: positive regulation of erythrocyte apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084]
synonym: "activation of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of erythrocyte apoptotic process" NARROW [GOC:TermGenie]
synonym: "activation of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of RBC apoptotic process" NARROW [GOC:TermGenie]
synonym: "activation of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of red blood cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "positive regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of RBC apoptotic process" EXACT [GOC:TermGenie]
synonym: "positive regulation of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of RBC apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of RBC apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of erythrocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of RBC apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of RBC apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of red blood cell apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0033034 ! positive regulation of myeloid cell apoptotic process
is_a: GO:1902250 ! regulation of erythrocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1902217 ! erythrocyte apoptotic process
relationship: positively_regulates GO:1902217 ! erythrocyte apoptotic process
property_value: RO:0002161 NCBITaxon:4751
created_by: rl
creation_date: 2013-06-20T19:31:04Z

[Term]
id: GO:1902256
name: regulation of apoptotic process involved in outflow tract morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542]
synonym: "regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis
relationship: regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis
created_by: dph
creation_date: 2013-06-24T19:12:24Z

[Term]
id: GO:1902257
name: negative regulation of apoptotic process involved in outflow tract morphogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542]
synonym: "down regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis
is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis
relationship: negatively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis
created_by: dph
creation_date: 2013-06-24T19:12:30Z

[Term]
id: GO:1902258
name: positive regulation of apoptotic process involved in outflow tract morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542]
synonym: "activation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis
is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis
relationship: positively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis
created_by: dph
creation_date: 2013-06-24T19:12:42Z

[Term]
id: GO:1902262
name: apoptotic process involved in blood vessel morphogenesis
namespace: biological_process
def: "Any apoptotic process that is involved in blood vessel morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16163358]
synonym: "apoptosis involved in patterning of blood vessels" NARROW [GOC:TermGenie]
synonym: "apoptotic cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie]
synonym: "apoptotic program involved in patterning of blood vessels" NARROW [GOC:TermGenie]
synonym: "apoptotic programmed cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie]
synonym: "programmed cell death by apoptosis involved in patterning of blood vessels" EXACT [GOC:TermGenie]
synonym: "signaling (initiator) caspase activity involved in patterning of blood vessels" RELATED [GOC:TermGenie]
synonym: "type I programmed cell death involved in patterning of blood vessels" NARROW [GOC:TermGenie]
is_a: GO:0060561 ! apoptotic process involved in morphogenesis
intersection_of: GO:0006915 ! apoptotic process
intersection_of: part_of GO:0048514 ! blood vessel morphogenesis
relationship: part_of GO:0048514 ! blood vessel morphogenesis
created_by: dph
creation_date: 2013-06-25T16:16:00Z

[Term]
id: GO:1902275
name: regulation of chromatin organization
namespace: biological_process
alt_id: GO:0001672
alt_id: GO:1903308
def: "Any process that modulates the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:bf, GOC:TermGenie, GOC:vw, PMID:18314879]
synonym: "regulation of chromatin assembly or disassembly" RELATED []
synonym: "regulation of chromatin assembly/disassembly" RELATED []
synonym: "regulation of chromatin modification" RELATED []
synonym: "regulation of chromatin organisation" EXACT [GOC:TermGenie]
synonym: "regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006325 ! chromatin organization
relationship: regulates GO:0006325 ! chromatin organization
created_by: bf
creation_date: 2013-07-01T13:21:52Z

[Term]
id: GO:1902305
name: regulation of sodium ion transmembrane transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664]
synonym: "regulation of sodium ion membrane transport" EXACT [GOC:TermGenie]
is_a: GO:0002028 ! regulation of sodium ion transport
is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035725 ! sodium ion transmembrane transport
relationship: regulates GO:0035725 ! sodium ion transmembrane transport
created_by: rl
creation_date: 2013-07-18T13:33:53Z

[Term]
id: GO:1902306
name: negative regulation of sodium ion transmembrane transport
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664]
synonym: "down regulation of sodium ion membrane transport" EXACT [GOC:TermGenie]
synonym: "down regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "down-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie]
synonym: "down-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "downregulation of sodium ion membrane transport" EXACT [GOC:TermGenie]
synonym: "downregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "inhibition of sodium ion membrane transport" NARROW [GOC:TermGenie]
synonym: "inhibition of sodium ion transmembrane transport" NARROW [GOC:TermGenie]
synonym: "negative regulation of sodium ion membrane transport" EXACT [GOC:TermGenie]
is_a: GO:0010766 ! negative regulation of sodium ion transport
is_a: GO:1902305 ! regulation of sodium ion transmembrane transport
is_a: GO:1904063 ! negative regulation of cation transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035725 ! sodium ion transmembrane transport
relationship: negatively_regulates GO:0035725 ! sodium ion transmembrane transport
created_by: rl
creation_date: 2013-07-18T13:34:01Z

[Term]
id: GO:1902307
name: positive regulation of sodium ion transmembrane transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664]
synonym: "activation of sodium ion membrane transport" NARROW [GOC:TermGenie]
synonym: "activation of sodium ion transmembrane transport" NARROW [GOC:TermGenie]
synonym: "positive regulation of sodium ion membrane transport" EXACT [GOC:TermGenie]
synonym: "up regulation of sodium ion membrane transport" EXACT [GOC:TermGenie]
synonym: "up regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "up-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie]
synonym: "up-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "upregulation of sodium ion membrane transport" EXACT [GOC:TermGenie]
synonym: "upregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie]
is_a: GO:0010765 ! positive regulation of sodium ion transport
is_a: GO:1902305 ! regulation of sodium ion transmembrane transport
is_a: GO:1904064 ! positive regulation of cation transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035725 ! sodium ion transmembrane transport
relationship: positively_regulates GO:0035725 ! sodium ion transmembrane transport
created_by: rl
creation_date: 2013-07-18T13:34:18Z

[Term]
id: GO:1902337
name: regulation of apoptotic process involved in morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035]
synonym: "regulation of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie]
is_a: GO:1904748 ! regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060561 ! apoptotic process involved in morphogenesis
relationship: regulates GO:0060561 ! apoptotic process involved in morphogenesis
created_by: sart
creation_date: 2013-07-29T15:03:16Z

[Term]
id: GO:1902338
name: negative regulation of apoptotic process involved in morphogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035]
synonym: "down regulation of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "down regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie]
synonym: "down regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie]
synonym: "down-regulation of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "down-regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie]
synonym: "downregulation of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "downregulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of morphogenetic apoptosis" RELATED [GOC:TermGenie]
synonym: "inhibition of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "inhibition of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic process involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of morphogenetic apoptosis" RELATED [GOC:TermGenie]
synonym: "negative regulation of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "negative regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "negative regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie]
is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis
is_a: GO:1904746 ! negative regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060561 ! apoptotic process involved in morphogenesis
relationship: negatively_regulates GO:0060561 ! apoptotic process involved in morphogenesis
created_by: sart
creation_date: 2013-07-29T15:03:25Z

[Term]
id: GO:1902339
name: positive regulation of apoptotic process involved in morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035]
synonym: "activation of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "activation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic process involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "activation of morphogenetic apoptosis" RELATED [GOC:TermGenie]
synonym: "positive regulation of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "positive regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie]
synonym: "up regulation of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "up regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie]
synonym: "up-regulation of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "up-regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie]
synonym: "upregulation of apoptosis involved in development" RELATED [GOC:TermGenie]
synonym: "upregulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of morphogenetic apoptosis" RELATED [GOC:TermGenie]
is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis
is_a: GO:1904747 ! positive regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060561 ! apoptotic process involved in morphogenesis
relationship: positively_regulates GO:0060561 ! apoptotic process involved in morphogenesis
created_by: sart
creation_date: 2013-07-29T15:03:33Z

[Term]
id: GO:1902340
name: negative regulation of chromosome condensation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation." [GOC:TermGenie, PMID:23219725]
synonym: "down regulation of chromosome condensation" EXACT [GOC:TermGenie]
synonym: "down regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie]
synonym: "down regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie]
synonym: "down-regulation of chromosome condensation" EXACT [GOC:TermGenie]
synonym: "down-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie]
synonym: "down-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie]
synonym: "downregulation of chromosome condensation" EXACT [GOC:TermGenie]
synonym: "downregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie]
synonym: "downregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie]
synonym: "inhibition of chromosome condensation" NARROW [GOC:TermGenie]
synonym: "inhibition of eukaryotic chromosome condensation" NARROW [GOC:TermGenie]
synonym: "inhibition of nuclear chromosome condensation" NARROW [GOC:TermGenie]
synonym: "negative regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie]
synonym: "negative regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie]
is_a: GO:0060623 ! regulation of chromosome condensation
is_a: GO:2001251 ! negative regulation of chromosome organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030261 ! chromosome condensation
relationship: negatively_regulates GO:0030261 ! chromosome condensation
created_by: dgf
creation_date: 2013-07-29T20:54:14Z

[Term]
id: GO:1902358
name: sulfate transmembrane transport
namespace: biological_process
def: "The directed movement of sulfate across a membrane." [GOC:dph, GOC:TermGenie, PMID:9055073]
is_a: GO:0008272 ! sulfate transport
is_a: GO:0098661 ! inorganic anion transmembrane transport
intersection_of: GO:0055085 ! transmembrane transport
intersection_of: has_primary_input CHEBI:16189 ! sulfate
created_by: dph
creation_date: 2013-08-14T14:46:04Z

[Term]
id: GO:1902369
name: negative regulation of RNA catabolic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process." [GOC:bf, GOC:TermGenie, PMID:16640457]
synonym: "down regulation of RNA breakdown" EXACT [GOC:TermGenie]
synonym: "down regulation of RNA catabolic process" EXACT [GOC:TermGenie]
synonym: "down regulation of RNA catabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of RNA degradation" EXACT [GOC:TermGenie]
synonym: "down-regulation of RNA breakdown" EXACT [GOC:TermGenie]
synonym: "down-regulation of RNA catabolic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of RNA catabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of RNA degradation" EXACT [GOC:TermGenie]
synonym: "downregulation of RNA breakdown" EXACT [GOC:TermGenie]
synonym: "downregulation of RNA catabolic process" EXACT [GOC:TermGenie]
synonym: "downregulation of RNA catabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of RNA degradation" EXACT [GOC:TermGenie]
synonym: "inhibition of RNA breakdown" NARROW [GOC:TermGenie]
synonym: "inhibition of RNA catabolic process" NARROW [GOC:TermGenie]
synonym: "inhibition of RNA catabolism" NARROW [GOC:TermGenie]
synonym: "inhibition of RNA degradation" NARROW [GOC:TermGenie]
synonym: "negative regulation of RNA breakdown" EXACT [GOC:TermGenie]
synonym: "negative regulation of RNA catabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of RNA degradation" EXACT [GOC:TermGenie]
is_a: GO:0031330 ! negative regulation of cellular catabolic process
is_a: GO:0051253 ! negative regulation of RNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006401 ! RNA catabolic process
relationship: negatively_regulates GO:0006401 ! RNA catabolic process
created_by: bf
creation_date: 2013-08-22T14:59:39Z

[Term]
id: GO:1902414
name: protein localization to cell junction
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a cell junction." [GOC:TermGenie, PMID:18332111]
synonym: "protein localisation in cell junction" EXACT [GOC:TermGenie]
synonym: "protein localisation to cell junction" EXACT [GOC:TermGenie]
synonym: "protein localization in cell junction" EXACT [GOC:TermGenie]
is_a: GO:0008104 ! protein localization
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0030054 ! cell junction
relationship: has_target_end_location GO:0030054 ! cell junction
created_by: tb
creation_date: 2013-09-13T16:55:57Z

[Term]
id: GO:1902455
name: negative regulation of stem cell population maintenance
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033]
synonym: "down regulation of maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "down regulation of stem cell maintenance" EXACT [GOC:TermGenie]
synonym: "down-regulation of maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "down-regulation of stem cell maintenance" EXACT [GOC:TermGenie]
synonym: "downregulation of maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "downregulation of stem cell maintenance" EXACT [GOC:TermGenie]
synonym: "inhibition of maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "inhibition of stem cell maintenance" NARROW [GOC:TermGenie]
synonym: "negative regulation of maintenance of pluripotency" RELATED [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:2000036 ! regulation of stem cell population maintenance
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0019827 ! stem cell population maintenance
relationship: negatively_regulates GO:0019827 ! stem cell population maintenance
created_by: cjm
creation_date: 2013-10-16T22:19:17Z

[Term]
id: GO:1902459
name: positive regulation of stem cell population maintenance
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033]
synonym: "activation of maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "activation of stem cell maintenance" NARROW [GOC:TermGenie]
synonym: "positive regulation of maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "up regulation of maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "up regulation of stem cell maintenance" EXACT [GOC:TermGenie]
synonym: "up-regulation of maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "up-regulation of stem cell maintenance" EXACT [GOC:TermGenie]
synonym: "upregulation of maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "upregulation of stem cell maintenance" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:2000036 ! regulation of stem cell population maintenance
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0019827 ! stem cell population maintenance
relationship: positively_regulates GO:0019827 ! stem cell population maintenance
created_by: cjm
creation_date: 2013-10-16T22:27:47Z

[Term]
id: GO:1902463
name: protein localization to cell leading edge
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a cell leading edge." [GOC:lb, GOC:TermGenie, PMID:21543326]
synonym: "protein localisation in cell leading edge" EXACT [GOC:TermGenie]
synonym: "protein localisation to cell leading edge" EXACT [GOC:TermGenie]
synonym: "protein localization in cell leading edge" EXACT [GOC:TermGenie]
is_a: GO:0008104 ! protein localization
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0031252 ! cell leading edge
relationship: has_target_end_location GO:0031252 ! cell leading edge
created_by: jl
creation_date: 2013-10-22T12:36:07Z

[Term]
id: GO:1902473
name: regulation of protein localization to synapse
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719]
synonym: "regulation of protein localisation to synapse" EXACT [GOC:TermGenie]
is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035418 ! protein localization to synapse
relationship: regulates GO:0035418 ! protein localization to synapse
created_by: kmv
creation_date: 2013-10-25T15:09:09Z

[Term]
id: GO:1902474
name: positive regulation of protein localization to synapse
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719]
synonym: "activation of protein localisation to synapse" NARROW [GOC:TermGenie]
synonym: "activation of protein localization to synapse" NARROW [GOC:TermGenie]
synonym: "positive regulation of protein localisation to synapse" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation to synapse" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization to synapse" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation to synapse" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to synapse" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation to synapse" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to synapse" EXACT [GOC:TermGenie]
is_a: GO:1902473 ! regulation of protein localization to synapse
is_a: GO:1903829 ! positive regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035418 ! protein localization to synapse
relationship: positively_regulates GO:0035418 ! protein localization to synapse
created_by: kmv
creation_date: 2013-10-25T15:09:18Z

[Term]
id: GO:1902484
name: Sertoli cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a Sertoli cell." [GOC:ic, GOC:TermGenie, PMID:17761895]
synonym: "Sertoli cell apoptosis" NARROW [GOC:TermGenie]
is_a: GO:1904019 ! epithelial cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000216 ! Sertoli cell
relationship: occurs_in CL:0000216 ! Sertoli cell
created_by: pr
creation_date: 2013-11-06T11:27:34Z

[Term]
id: GO:1902488
name: cholangiocyte apoptotic process
namespace: biological_process
def: "Any apoptotic process in a cholangiocyte." [GOC:TermGenie, PMID:22961800]
synonym: "cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:1904019 ! epithelial cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:1000488 ! cholangiocyte
relationship: occurs_in CL:1000488 ! cholangiocyte
created_by: cls
creation_date: 2013-11-12T15:30:08Z

[Term]
id: GO:1902489
name: hepatoblast apoptotic process
namespace: biological_process
def: "Any apoptotic process in a hepatoblast." [GOC:TermGenie, PMID:22412967]
synonym: "hepatoblast apoptosis" NARROW [GOC:TermGenie]
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0005026 ! hepatoblast
relationship: occurs_in CL:0005026 ! hepatoblast
created_by: cls
creation_date: 2013-11-12T17:02:52Z

[Term]
id: GO:1902490
name: regulation of sperm capacitation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676]
synonym: "regulation of sperm activation" RELATED [GOC:TermGenie]
is_a: GO:0051239 ! regulation of multicellular organismal process
is_a: GO:1903429 ! regulation of cell maturation
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048240 ! sperm capacitation
relationship: regulates GO:0048240 ! sperm capacitation
created_by: hjd
creation_date: 2013-11-12T21:17:03Z

[Term]
id: GO:1902491
name: negative regulation of sperm capacitation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676]
synonym: "down regulation of sperm activation" RELATED [GOC:TermGenie]
synonym: "down regulation of sperm capacitation" EXACT [GOC:TermGenie]
synonym: "down-regulation of sperm activation" RELATED [GOC:TermGenie]
synonym: "down-regulation of sperm capacitation" EXACT [GOC:TermGenie]
synonym: "downregulation of sperm activation" RELATED [GOC:TermGenie]
synonym: "downregulation of sperm capacitation" EXACT [GOC:TermGenie]
synonym: "inhibition of sperm activation" RELATED [GOC:TermGenie]
synonym: "inhibition of sperm capacitation" NARROW [GOC:TermGenie]
synonym: "negative regulation of sperm activation" RELATED [GOC:TermGenie]
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1902490 ! regulation of sperm capacitation
is_a: GO:1903430 ! negative regulation of cell maturation
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048240 ! sperm capacitation
relationship: negatively_regulates GO:0048240 ! sperm capacitation
created_by: hjd
creation_date: 2013-11-12T21:17:12Z

[Term]
id: GO:1902492
name: positive regulation of sperm capacitation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676]
synonym: "activation of sperm activation" RELATED [GOC:TermGenie]
synonym: "activation of sperm capacitation" NARROW [GOC:TermGenie]
synonym: "positive regulation of sperm activation" RELATED [GOC:TermGenie]
synonym: "up regulation of sperm activation" RELATED [GOC:TermGenie]
synonym: "up regulation of sperm capacitation" EXACT [GOC:TermGenie]
synonym: "up-regulation of sperm activation" RELATED [GOC:TermGenie]
synonym: "up-regulation of sperm capacitation" EXACT [GOC:TermGenie]
synonym: "upregulation of sperm activation" RELATED [GOC:TermGenie]
synonym: "upregulation of sperm capacitation" EXACT [GOC:TermGenie]
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1902490 ! regulation of sperm capacitation
is_a: GO:1903431 ! positive regulation of cell maturation
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048240 ! sperm capacitation
relationship: positively_regulates GO:0048240 ! sperm capacitation
created_by: hjd
creation_date: 2013-11-12T21:17:21Z

[Term]
id: GO:1902494
name: catalytic complex
namespace: cellular_component
def: "A protein complex which is capable of catalytic activity." [GOC:bhm, GOC:TermGenie, PMID:8077207]
subset: goslim_metagenomics
synonym: "enzyme complex" EXACT [GOC:bhm, GOC:jl]
is_a: GO:0032991 ! protein-containing complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: capable_of GO:0003824 ! catalytic activity
relationship: capable_of GO:0003824 ! catalytic activity
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19980" xsd:anyURI
created_by: bhm
creation_date: 2013-11-13T16:18:47Z

[Term]
id: GO:1902495
name: transmembrane transporter complex
namespace: cellular_component
def: "A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other." [GOC:bhm, GOC:TermGenie, PMID:18024586]
is_a: GO:0098796 ! membrane protein complex
is_a: GO:1990351 ! transporter complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: capable_of GO:0022857 ! transmembrane transporter activity
relationship: capable_of GO:0022857 ! transmembrane transporter activity
created_by: bhm
creation_date: 2013-11-13T16:23:04Z

[Term]
id: GO:1902510
name: regulation of apoptotic DNA fragmentation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351, PMID:15723341]
comment: DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases (see GO:0006309 'apoptotic DNA fragmentation'). Gene products involved in compartmentalization of such nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).
synonym: "regulation of chromatinolysis" BROAD [GOC:TermGenie]
synonym: "regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie]
synonym: "regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie]
synonym: "regulation of DNA fragmentation" BROAD [GOC:TermGenie]
synonym: "regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie]
synonym: "regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie]
is_a: GO:1903624 ! regulation of DNA catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006309 ! apoptotic DNA fragmentation
relationship: regulates GO:0006309 ! apoptotic DNA fragmentation
created_by: hjd
creation_date: 2013-11-15T18:28:32Z

[Term]
id: GO:1902511
name: negative regulation of apoptotic DNA fragmentation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351]
synonym: "down regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie]
synonym: "down regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie]
synonym: "down regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie]
synonym: "down regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie]
synonym: "down regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie]
synonym: "down-regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie]
synonym: "down-regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie]
synonym: "down-regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie]
synonym: "down-regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie]
synonym: "downregulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie]
synonym: "downregulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie]
synonym: "downregulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie]
synonym: "downregulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie]
synonym: "inhibition of apoptotic DNA fragmentation" NARROW [GOC:TermGenie]
synonym: "inhibition of DNA catabolic process during apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of DNA catabolism during apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of DNA fragmentation involved in apoptotic nuclear change" NARROW [GOC:TermGenie]
synonym: "inhibition of endonucleolytic DNA catabolic process involved in apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie]
synonym: "negative regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie]
synonym: "negative regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie]
synonym: "negative regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie]
is_a: GO:1902510 ! regulation of apoptotic DNA fragmentation
is_a: GO:1903625 ! negative regulation of DNA catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006309 ! apoptotic DNA fragmentation
relationship: negatively_regulates GO:0006309 ! apoptotic DNA fragmentation
created_by: hjd
creation_date: 2013-11-15T18:28:41Z

[Term]
id: GO:1902512
name: positive regulation of apoptotic DNA fragmentation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351]
synonym: "activation of apoptotic DNA fragmentation" NARROW [GOC:TermGenie]
synonym: "activation of DNA catabolic process during apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of DNA catabolism during apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of DNA fragmentation involved in apoptotic nuclear change" NARROW [GOC:TermGenie]
synonym: "activation of endonucleolytic DNA catabolic process involved in apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie]
synonym: "positive regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie]
synonym: "positive regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie]
synonym: "positive regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie]
synonym: "up regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie]
synonym: "up regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie]
synonym: "up regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie]
synonym: "up regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie]
synonym: "up-regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie]
synonym: "up-regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie]
synonym: "up-regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie]
synonym: "up-regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie]
synonym: "upregulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie]
synonym: "upregulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie]
synonym: "upregulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie]
synonym: "upregulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie]
is_a: GO:1902510 ! regulation of apoptotic DNA fragmentation
is_a: GO:1903626 ! positive regulation of DNA catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006309 ! apoptotic DNA fragmentation
relationship: positively_regulates GO:0006309 ! apoptotic DNA fragmentation
created_by: hjd
creation_date: 2013-11-15T18:28:50Z

[Term]
id: GO:1902513
name: regulation of organelle transport along microtubule
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of organelle transport along microtubule." [GOC:dph, GOC:TermGenie, PMID:21147087]
synonym: "regulation of microtubule-based organelle localization" EXACT [GOC:TermGenie]
is_a: GO:0032386 ! regulation of intracellular transport
is_a: GO:0060632 ! regulation of microtubule-based movement
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072384 ! organelle transport along microtubule
relationship: regulates GO:0072384 ! organelle transport along microtubule
created_by: dph
creation_date: 2013-11-15T20:15:17Z

[Term]
id: GO:1902531
name: regulation of intracellular signal transduction
namespace: biological_process
alt_id: GO:0010627
def: "Any process that modulates the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie]
synonym: "regulation of intracellular protein kinase cascade" NARROW []
synonym: "regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "regulation of intracellular signaling cascade" EXACT [GOC:TermGenie]
synonym: "regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
is_a: GO:0009966 ! regulation of signal transduction
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035556 ! intracellular signal transduction
relationship: regulates GO:0035556 ! intracellular signal transduction
created_by: bf
creation_date: 2013-12-02T11:32:52Z

[Term]
id: GO:1902532
name: negative regulation of intracellular signal transduction
namespace: biological_process
alt_id: GO:0010741
def: "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie]
synonym: "down regulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "down regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "down regulation of intracellular signaling cascade" NARROW [GOC:TermGenie]
synonym: "down regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "down regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "down regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "down regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "down-regulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "down-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "down-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "down-regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "down-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "down-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "down-regulation of signal transmission via intracellular cascade" RELATED [GOC:TermGenie]
synonym: "downregulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "downregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "downregulation of intracellular signaling cascade" NARROW [GOC:TermGenie]
synonym: "downregulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "downregulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "downregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "downregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "inhibition of intracellular signal transduction" NARROW [GOC:TermGenie]
synonym: "inhibition of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "inhibition of intracellular signaling cascade" NARROW [GOC:TermGenie]
synonym: "inhibition of intracellular signaling chain" NARROW [GOC:TermGenie]
synonym: "inhibition of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "inhibition of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "inhibition of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "negative regulation of intracellular protein kinase cascade" EXACT []
synonym: "negative regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "negative regulation of intracellular signaling cascade" EXACT [GOC:TermGenie]
synonym: "negative regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "negative regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "negative regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "negative regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
is_a: GO:0009968 ! negative regulation of signal transduction
is_a: GO:1902531 ! regulation of intracellular signal transduction
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035556 ! intracellular signal transduction
relationship: negatively_regulates GO:0035556 ! intracellular signal transduction
created_by: bf
creation_date: 2013-12-02T11:33:01Z

[Term]
id: GO:1902533
name: positive regulation of intracellular signal transduction
namespace: biological_process
alt_id: GO:0010740
def: "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." [GOC:BHF, GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie]
synonym: "activation of intracellular signal transduction" NARROW [GOC:TermGenie]
synonym: "activation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "activation of intracellular signaling cascade" NARROW [GOC:TermGenie]
synonym: "activation of intracellular signaling chain" NARROW [GOC:TermGenie]
synonym: "activation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "activation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "activation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "positive regulation of intracellular protein kinase cascade" NARROW []
synonym: "positive regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "positive regulation of intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "positive regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "positive regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "positive regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "positive regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "up regulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "up regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "up regulation of intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "up regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "up regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "up regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "up regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "up-regulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "up-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "up-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "up-regulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "up-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "up-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "up-regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
synonym: "upregulation of intracellular signal transduction" EXACT [GOC:TermGenie]
synonym: "upregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie]
synonym: "upregulation of intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "upregulation of intracellular signaling chain" EXACT [GOC:TermGenie]
synonym: "upregulation of intracellular signaling pathway" RELATED [GOC:TermGenie]
synonym: "upregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie]
synonym: "upregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie]
is_a: GO:0009967 ! positive regulation of signal transduction
is_a: GO:1902531 ! regulation of intracellular signal transduction
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035556 ! intracellular signal transduction
relationship: positively_regulates GO:0035556 ! intracellular signal transduction
created_by: bf
creation_date: 2013-12-02T11:33:10Z

[Term]
id: GO:1902570
name: protein localization to nucleolus
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a nucleolus." [GOC:TermGenie, PMID:22809626]
synonym: "protein localisation in nucleolus" EXACT [GOC:TermGenie]
synonym: "protein localisation to nucleolus" EXACT [GOC:TermGenie]
synonym: "protein localization in nucleolus" EXACT [GOC:TermGenie]
is_a: GO:0034504 ! protein localization to nucleus
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005730 ! nucleolus
relationship: has_target_end_location GO:0005730 ! nucleolus
created_by: mah
creation_date: 2013-12-10T16:25:28Z

[Term]
id: GO:1902679
name: negative regulation of RNA biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie]
synonym: "down regulation of RNA anabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of RNA biosynthesis" EXACT [GOC:TermGenie]
synonym: "down regulation of RNA biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down regulation of RNA formation" EXACT [GOC:TermGenie]
synonym: "down regulation of RNA synthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of RNA anabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of RNA biosynthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of RNA formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of RNA synthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of RNA anabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of RNA biosynthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of RNA biosynthetic process" EXACT [GOC:TermGenie]
synonym: "downregulation of RNA formation" EXACT [GOC:TermGenie]
synonym: "downregulation of RNA synthesis" EXACT [GOC:TermGenie]
synonym: "inhibition of RNA anabolism" NARROW [GOC:TermGenie]
synonym: "inhibition of RNA biosynthesis" NARROW [GOC:TermGenie]
synonym: "inhibition of RNA biosynthetic process" NARROW [GOC:TermGenie]
synonym: "inhibition of RNA formation" NARROW [GOC:TermGenie]
synonym: "inhibition of RNA synthesis" NARROW [GOC:TermGenie]
synonym: "negative regulation of RNA anabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of RNA biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of RNA formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of RNA synthesis" EXACT [GOC:TermGenie]
is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process
is_a: GO:0051253 ! negative regulation of RNA metabolic process
is_a: GO:2001141 ! regulation of RNA biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032774 ! RNA biosynthetic process
relationship: negatively_regulates GO:0032774 ! RNA biosynthetic process
created_by: jl
creation_date: 2014-02-05T16:32:01Z

[Term]
id: GO:1902680
name: positive regulation of RNA biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie]
synonym: "activation of RNA anabolism" NARROW [GOC:TermGenie]
synonym: "activation of RNA biosynthesis" NARROW [GOC:TermGenie]
synonym: "activation of RNA biosynthetic process" NARROW [GOC:TermGenie]
synonym: "activation of RNA formation" NARROW [GOC:TermGenie]
synonym: "activation of RNA synthesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of RNA anabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of RNA biosynthesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of RNA formation" EXACT [GOC:TermGenie]
synonym: "positive regulation of RNA synthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of RNA anabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of RNA biosynthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of RNA biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up regulation of RNA formation" EXACT [GOC:TermGenie]
synonym: "up regulation of RNA synthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of RNA anabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of RNA biosynthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of RNA formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of RNA synthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of RNA anabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of RNA biosynthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of RNA biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of RNA formation" EXACT [GOC:TermGenie]
synonym: "upregulation of RNA synthesis" EXACT [GOC:TermGenie]
is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process
is_a: GO:0051254 ! positive regulation of RNA metabolic process
is_a: GO:2001141 ! regulation of RNA biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032774 ! RNA biosynthetic process
relationship: positively_regulates GO:0032774 ! RNA biosynthetic process
created_by: jl
creation_date: 2014-02-05T16:32:10Z

[Term]
id: GO:1902692
name: regulation of neuroblast proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neuroblast proliferation." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:21168496]
is_a: GO:2000177 ! regulation of neural precursor cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007405 ! neuroblast proliferation
relationship: regulates GO:0007405 ! neuroblast proliferation
created_by: rl
creation_date: 2014-02-18T10:03:31Z

[Term]
id: GO:1902738
name: regulation of chondrocyte differentiation involved in endochondral bone morphogenesis
namespace: biological_process
def: "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GO_REF:0000058, GOC:TermGenie, PMID:8662546]
is_a: GO:0032330 ! regulation of chondrocyte differentiation
is_a: GO:1903010 ! regulation of bone development
is_a: GO:2000027 ! regulation of animal organ morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis
relationship: regulates GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis
created_by: mr
creation_date: 2014-02-26T15:36:15Z

[Term]
id: GO:1902742
name: apoptotic process involved in development
namespace: biological_process
def: "Any apoptotic process that is involved in anatomical structure development." [GO_REF:0000060, GOC:mtg_apoptosis, GOC:pg, GOC:TermGenie]
synonym: "activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "apoptotic process involved in anatomical structure development" EXACT []
synonym: "apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: part_of GO:0048856 ! anatomical structure development
relationship: part_of GO:0048856 ! anatomical structure development
created_by: pr
creation_date: 2014-02-28T13:09:43Z

[Term]
id: GO:1902761
name: positive regulation of chondrocyte development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of chondrocyte development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16575901]
synonym: "activation of chondrocyte development" NARROW [GOC:TermGenie]
synonym: "up regulation of chondrocyte development" EXACT [GOC:TermGenie]
synonym: "up-regulation of chondrocyte development" EXACT [GOC:TermGenie]
synonym: "upregulation of chondrocyte development" EXACT [GOC:TermGenie]
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0032332 ! positive regulation of chondrocyte differentiation
is_a: GO:0061181 ! regulation of chondrocyte development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002063 ! chondrocyte development
relationship: positively_regulates GO:0002063 ! chondrocyte development
created_by: mr
creation_date: 2014-03-07T17:45:55Z

[Term]
id: GO:1902809
name: regulation of skeletal muscle fiber differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321]
is_a: GO:0010830 ! regulation of myotube differentiation
is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0098528 ! skeletal muscle fiber differentiation
relationship: regulates GO:0098528 ! skeletal muscle fiber differentiation
created_by: mr
creation_date: 2014-03-26T21:18:26Z

[Term]
id: GO:1902810
name: negative regulation of skeletal muscle fiber differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321]
synonym: "down regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of skeletal muscle fiber differentiation" NARROW [GOC:TermGenie]
is_a: GO:0010832 ! negative regulation of myotube differentiation
is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation
is_a: GO:2001015 ! negative regulation of skeletal muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0098528 ! skeletal muscle fiber differentiation
relationship: negatively_regulates GO:0098528 ! skeletal muscle fiber differentiation
created_by: mr
creation_date: 2014-03-26T21:18:32Z

[Term]
id: GO:1902811
name: positive regulation of skeletal muscle fiber differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321]
synonym: "activation of skeletal muscle fiber differentiation" NARROW [GOC:TermGenie]
synonym: "up regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie]
is_a: GO:0010831 ! positive regulation of myotube differentiation
is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation
is_a: GO:2001016 ! positive regulation of skeletal muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0098528 ! skeletal muscle fiber differentiation
relationship: positively_regulates GO:0098528 ! skeletal muscle fiber differentiation
created_by: mr
creation_date: 2014-03-26T21:18:38Z

[Term]
id: GO:1902816
name: regulation of protein localization to microtubule
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209]
synonym: "regulation of protein localisation to microtubule" EXACT [GOC:TermGenie]
is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035372 ! protein localization to microtubule
relationship: regulates GO:0035372 ! protein localization to microtubule
created_by: tb
creation_date: 2014-03-27T22:07:12Z

[Term]
id: GO:1902817
name: negative regulation of protein localization to microtubule
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209]
synonym: "down regulation of protein localisation to microtubule" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization to microtubule" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation to microtubule" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to microtubule" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation to microtubule" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to microtubule" EXACT [GOC:TermGenie]
synonym: "inhibition of protein localisation to microtubule" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization to microtubule" NARROW [GOC:TermGenie]
synonym: "negative regulation of protein localisation to microtubule" EXACT [GOC:TermGenie]
is_a: GO:1902816 ! regulation of protein localization to microtubule
is_a: GO:1903828 ! negative regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035372 ! protein localization to microtubule
relationship: negatively_regulates GO:0035372 ! protein localization to microtubule
created_by: tb
creation_date: 2014-03-27T22:07:18Z

[Term]
id: GO:1902838
name: regulation of nuclear migration along microtubule
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209]
synonym: "regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie]
synonym: "regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "regulation of nuclear movement, microtubule-mediated" BROAD [GOC:TermGenie]
synonym: "regulation of nucleus migration" BROAD [GOC:TermGenie]
synonym: "regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie]
synonym: "regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie]
is_a: GO:1902513 ! regulation of organelle transport along microtubule
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030473 ! nuclear migration along microtubule
relationship: regulates GO:0030473 ! nuclear migration along microtubule
created_by: vw
creation_date: 2014-04-01T13:50:23Z

[Term]
id: GO:1902839
name: negative regulation of nuclear migration along microtubule
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209]
synonym: "down regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "down regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "down regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "down regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "down regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie]
synonym: "down regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie]
synonym: "down regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "down regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie]
synonym: "down regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "down-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "down-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "down-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "down-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "down-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie]
synonym: "down-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie]
synonym: "down-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "down-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie]
synonym: "down-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "downregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "downregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "downregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "downregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "downregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie]
synonym: "downregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie]
synonym: "downregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "downregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie]
synonym: "downregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "inhibition of microtubule cytoskeleton-dependent nuclear positioning" NARROW [GOC:TermGenie]
synonym: "inhibition of microtubule cytoskeleton-dependent nucleus positioning" NARROW [GOC:TermGenie]
synonym: "inhibition of microtubule-dependent nuclear positioning" NARROW [GOC:TermGenie]
synonym: "inhibition of microtubule-dependent nucleus positioning" NARROW [GOC:TermGenie]
synonym: "inhibition of microtubule-mediated nuclear migration" NARROW [GOC:TermGenie]
synonym: "inhibition of nuclear migration along microtubule" NARROW [GOC:TermGenie]
synonym: "inhibition of nuclear migration, microtubule-mediated" NARROW [GOC:TermGenie]
synonym: "inhibition of transport of nucleus by microtubules" NARROW [GOC:TermGenie]
synonym: "inhibition of transport of nucleus, microtubule-mediated" NARROW [GOC:TermGenie]
synonym: "negative regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "negative regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "negative regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "negative regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "negative regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie]
synonym: "negative regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "negative regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie]
synonym: "negative regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie]
is_a: GO:0032387 ! negative regulation of intracellular transport
is_a: GO:1902838 ! regulation of nuclear migration along microtubule
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030473 ! nuclear migration along microtubule
relationship: negatively_regulates GO:0030473 ! nuclear migration along microtubule
created_by: vw
creation_date: 2014-04-01T13:50:29Z

[Term]
id: GO:1902840
name: positive regulation of nuclear migration along microtubule
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209]
synonym: "activation of microtubule cytoskeleton-dependent nuclear positioning" NARROW [GOC:TermGenie]
synonym: "activation of microtubule cytoskeleton-dependent nucleus positioning" NARROW [GOC:TermGenie]
synonym: "activation of microtubule-dependent nuclear positioning" NARROW [GOC:TermGenie]
synonym: "activation of microtubule-dependent nucleus positioning" NARROW [GOC:TermGenie]
synonym: "activation of microtubule-mediated nuclear migration" NARROW [GOC:TermGenie]
synonym: "activation of nuclear migration along microtubule" NARROW [GOC:TermGenie]
synonym: "activation of nuclear migration, microtubule-mediated" NARROW [GOC:TermGenie]
synonym: "activation of transport of nucleus by microtubules" NARROW [GOC:TermGenie]
synonym: "activation of transport of nucleus, microtubule-mediated" NARROW [GOC:TermGenie]
synonym: "positive regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "positive regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "positive regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "positive regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "positive regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie]
synonym: "positive regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "positive regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie]
synonym: "positive regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "up regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "up regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "up regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "up regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "up regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie]
synonym: "up regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie]
synonym: "up regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "up regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie]
synonym: "up regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "up-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "up-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "up-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "up-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "up-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie]
synonym: "up-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie]
synonym: "up-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "up-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie]
synonym: "up-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "upregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "upregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "upregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie]
synonym: "upregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie]
synonym: "upregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie]
synonym: "upregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie]
synonym: "upregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie]
synonym: "upregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie]
synonym: "upregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie]
is_a: GO:0032388 ! positive regulation of intracellular transport
is_a: GO:1902838 ! regulation of nuclear migration along microtubule
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030473 ! nuclear migration along microtubule
relationship: positively_regulates GO:0030473 ! nuclear migration along microtubule
created_by: vw
creation_date: 2014-04-01T13:50:35Z

[Term]
id: GO:1902850
name: microtubule cytoskeleton organization involved in mitosis
namespace: biological_process
def: "Any microtubule cytoskeleton organization that is involved in mitosis." [GO_REF:0000060, GOC:TermGenie, PMID:18799626]
synonym: "microtubule cytoskeleton organisation involved in mitosis" EXACT [GOC:TermGenie]
synonym: "microtubule cytoskeleton organization and biogenesis involved in mitosis" RELATED [GOC:TermGenie]
synonym: "microtubule dynamics involved in mitosis" EXACT [GOC:TermGenie]
is_a: GO:0000226 ! microtubule cytoskeleton organization
is_a: GO:1903047 ! mitotic cell cycle process
intersection_of: GO:0000226 ! microtubule cytoskeleton organization
intersection_of: part_of GO:0000278 ! mitotic cell cycle
created_by: vw
creation_date: 2014-04-02T14:19:38Z

[Term]
id: GO:1902863
name: regulation of embryonic camera-type eye development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597]
synonym: "regulation of embryonic eye development" EXACT [GOC:TermGenie]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0031076 ! embryonic camera-type eye development
relationship: regulates GO:0031076 ! embryonic camera-type eye development
created_by: mr
creation_date: 2014-04-03T15:24:00Z

[Term]
id: GO:1902864
name: negative regulation of embryonic camera-type eye development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597]
synonym: "down regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie]
synonym: "down regulation of embryonic eye development" EXACT [GOC:TermGenie]
synonym: "down-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie]
synonym: "down-regulation of embryonic eye development" EXACT [GOC:TermGenie]
synonym: "downregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie]
synonym: "downregulation of embryonic eye development" EXACT [GOC:TermGenie]
synonym: "inhibition of embryonic camera-type eye development" NARROW [GOC:TermGenie]
synonym: "inhibition of embryonic eye development" NARROW [GOC:TermGenie]
synonym: "negative regulation of embryonic eye development" EXACT [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:1902863 ! regulation of embryonic camera-type eye development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0031076 ! embryonic camera-type eye development
relationship: negatively_regulates GO:0031076 ! embryonic camera-type eye development
created_by: mr
creation_date: 2014-04-03T15:24:06Z

[Term]
id: GO:1902865
name: positive regulation of embryonic camera-type eye development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597]
synonym: "activation of embryonic camera-type eye development" NARROW [GOC:TermGenie]
synonym: "activation of embryonic eye development" NARROW [GOC:TermGenie]
synonym: "positive regulation of embryonic eye development" EXACT [GOC:TermGenie]
synonym: "up regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie]
synonym: "up regulation of embryonic eye development" EXACT [GOC:TermGenie]
synonym: "up-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie]
synonym: "up-regulation of embryonic eye development" EXACT [GOC:TermGenie]
synonym: "upregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie]
synonym: "upregulation of embryonic eye development" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:1902863 ! regulation of embryonic camera-type eye development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0031076 ! embryonic camera-type eye development
relationship: positively_regulates GO:0031076 ! embryonic camera-type eye development
created_by: mr
creation_date: 2014-04-03T15:24:12Z

[Term]
id: GO:1902866
name: regulation of retina development in camera-type eye
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597]
synonym: "regulation of retina development in camera-style eye" EXACT [GOC:TermGenie]
synonym: "regulation of retinal development" RELATED [GOC:TermGenie]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060041 ! retina development in camera-type eye
relationship: regulates GO:0060041 ! retina development in camera-type eye
created_by: mr
creation_date: 2014-04-03T15:24:17Z

[Term]
id: GO:1902867
name: negative regulation of retina development in camera-type eye
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597]
synonym: "down regulation of retina development in camera-style eye" EXACT [GOC:TermGenie]
synonym: "down regulation of retina development in camera-type eye" EXACT [GOC:TermGenie]
synonym: "down regulation of retinal development" RELATED [GOC:TermGenie]
synonym: "down-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie]
synonym: "down-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie]
synonym: "down-regulation of retinal development" RELATED [GOC:TermGenie]
synonym: "downregulation of retina development in camera-style eye" EXACT [GOC:TermGenie]
synonym: "downregulation of retina development in camera-type eye" EXACT [GOC:TermGenie]
synonym: "downregulation of retinal development" RELATED [GOC:TermGenie]
synonym: "inhibition of retina development in camera-style eye" NARROW [GOC:TermGenie]
synonym: "inhibition of retina development in camera-type eye" NARROW [GOC:TermGenie]
synonym: "inhibition of retinal development" RELATED [GOC:TermGenie]
synonym: "negative regulation of retina development in camera-style eye" EXACT [GOC:TermGenie]
synonym: "negative regulation of retinal development" RELATED [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1902866 ! regulation of retina development in camera-type eye
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060041 ! retina development in camera-type eye
relationship: negatively_regulates GO:0060041 ! retina development in camera-type eye
created_by: mr
creation_date: 2014-04-03T15:24:23Z

[Term]
id: GO:1902868
name: positive regulation of retina development in camera-type eye
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597]
synonym: "activation of retina development in camera-style eye" NARROW [GOC:TermGenie]
synonym: "activation of retina development in camera-type eye" NARROW [GOC:TermGenie]
synonym: "activation of retinal development" RELATED [GOC:TermGenie]
synonym: "positive regulation of retina development in camera-style eye" EXACT [GOC:TermGenie]
synonym: "positive regulation of retinal development" RELATED [GOC:TermGenie]
synonym: "up regulation of retina development in camera-style eye" EXACT [GOC:TermGenie]
synonym: "up regulation of retina development in camera-type eye" EXACT [GOC:TermGenie]
synonym: "up regulation of retinal development" RELATED [GOC:TermGenie]
synonym: "up-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie]
synonym: "up-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie]
synonym: "up-regulation of retinal development" RELATED [GOC:TermGenie]
synonym: "upregulation of retina development in camera-style eye" EXACT [GOC:TermGenie]
synonym: "upregulation of retina development in camera-type eye" EXACT [GOC:TermGenie]
synonym: "upregulation of retinal development" RELATED [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1902866 ! regulation of retina development in camera-type eye
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060041 ! retina development in camera-type eye
relationship: positively_regulates GO:0060041 ! retina development in camera-type eye
created_by: mr
creation_date: 2014-04-03T15:24:29Z

[Term]
id: GO:1902875
name: regulation of embryonic pattern specification
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597]
synonym: "regulation of embryonic pattern biosynthesis" BROAD [GOC:TermGenie]
synonym: "regulation of embryonic pattern formation" BROAD [GOC:TermGenie]
synonym: "regulation of ventral/lateral system" RELATED [GOC:TermGenie]
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009880 ! embryonic pattern specification
relationship: regulates GO:0009880 ! embryonic pattern specification
created_by: mr
creation_date: 2014-04-03T15:25:15Z

[Term]
id: GO:1902876
name: negative regulation of embryonic pattern specification
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597]
synonym: "down regulation of embryonic pattern specification" EXACT [GOC:TermGenie]
synonym: "down regulation of ventral/lateral system" RELATED [GOC:TermGenie]
synonym: "down-regulation of embryonic pattern specification" EXACT [GOC:TermGenie]
synonym: "down-regulation of ventral/lateral system" RELATED [GOC:TermGenie]
synonym: "downregulation of embryonic pattern specification" EXACT [GOC:TermGenie]
synonym: "downregulation of ventral/lateral system" RELATED [GOC:TermGenie]
synonym: "inhibition of embryonic pattern specification" NARROW [GOC:TermGenie]
synonym: "inhibition of ventral/lateral system" RELATED [GOC:TermGenie]
synonym: "negative regulation of ventral/lateral system" RELATED [GOC:TermGenie]
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1902875 ! regulation of embryonic pattern specification
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009880 ! embryonic pattern specification
relationship: negatively_regulates GO:0009880 ! embryonic pattern specification
created_by: mr
creation_date: 2014-04-03T15:25:20Z

[Term]
id: GO:1902877
name: positive regulation of embryonic pattern specification
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597]
synonym: "activation of embryonic pattern specification" NARROW [GOC:TermGenie]
synonym: "activation of ventral/lateral system" RELATED [GOC:TermGenie]
synonym: "positive regulation of ventral/lateral system" RELATED [GOC:TermGenie]
synonym: "up regulation of embryonic pattern specification" EXACT [GOC:TermGenie]
synonym: "up regulation of ventral/lateral system" RELATED [GOC:TermGenie]
synonym: "up-regulation of embryonic pattern specification" EXACT [GOC:TermGenie]
synonym: "up-regulation of ventral/lateral system" RELATED [GOC:TermGenie]
synonym: "upregulation of embryonic pattern specification" EXACT [GOC:TermGenie]
synonym: "upregulation of ventral/lateral system" RELATED [GOC:TermGenie]
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1902875 ! regulation of embryonic pattern specification
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009880 ! embryonic pattern specification
relationship: positively_regulates GO:0009880 ! embryonic pattern specification
created_by: mr
creation_date: 2014-04-03T15:25:26Z

[Term]
id: GO:1902903
name: regulation of supramolecular fiber organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388]
comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro
synonym: "regulation of fibril organisation" RELATED [GOC:TermGenie]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097435 ! supramolecular fiber organization
relationship: regulates GO:0097435 ! supramolecular fiber organization
created_by: rl
creation_date: 2014-04-15T16:46:36Z

[Term]
id: GO:1902904
name: negative regulation of supramolecular fiber organization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388]
comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro
synonym: "down regulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "down regulation of fibril organization" RELATED [GOC:TermGenie]
synonym: "down-regulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "down-regulation of fibril organization" RELATED [GOC:TermGenie]
synonym: "downregulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "downregulation of fibril organization" RELATED [GOC:TermGenie]
synonym: "inhibition of fibril organisation" NARROW [GOC:TermGenie]
synonym: "inhibition of fibril organization" NARROW [GOC:TermGenie]
synonym: "negative regulation of fibril organisation" RELATED [GOC:TermGenie]
is_a: GO:0051129 ! negative regulation of cellular component organization
is_a: GO:1902903 ! regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097435 ! supramolecular fiber organization
relationship: negatively_regulates GO:0097435 ! supramolecular fiber organization
created_by: rl
creation_date: 2014-04-15T16:46:42Z

[Term]
id: GO:1902905
name: positive regulation of supramolecular fiber organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388]
comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro
synonym: "activation of fibril organisation" NARROW [GOC:TermGenie]
synonym: "activation of fibril organization" NARROW [GOC:TermGenie]
synonym: "positive regulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "up regulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "up regulation of fibril organization" RELATED [GOC:TermGenie]
synonym: "up-regulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "up-regulation of fibril organization" RELATED [GOC:TermGenie]
synonym: "upregulation of fibril organisation" RELATED [GOC:TermGenie]
synonym: "upregulation of fibril organization" RELATED [GOC:TermGenie]
is_a: GO:0051130 ! positive regulation of cellular component organization
is_a: GO:1902903 ! regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097435 ! supramolecular fiber organization
relationship: positively_regulates GO:0097435 ! supramolecular fiber organization
created_by: rl
creation_date: 2014-04-15T16:46:48Z

[Term]
id: GO:1902913
name: positive regulation of neuroepithelial cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16916506]
synonym: "activation of neuroepithelial cell differentiation" NARROW [GOC:TermGenie]
synonym: "up regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0030858 ! positive regulation of epithelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060563 ! neuroepithelial cell differentiation
relationship: positively_regulates GO:0060563 ! neuroepithelial cell differentiation
created_by: mr
creation_date: 2014-04-18T21:06:42Z

[Term]
id: GO:1903008
name: organelle disassembly
namespace: biological_process
def: "The disaggregation of an organelle into its constituent components." [GO_REF:0000079, GOC:TermGenie]
synonym: "organelle degradation" EXACT []
is_a: GO:0006996 ! organelle organization
is_a: GO:0022411 ! cellular component disassembly
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0043226 ! organelle
relationship: results_in_disassembly_of GO:0043226 ! organelle
created_by: jl
creation_date: 2014-05-13T12:36:03Z

[Term]
id: GO:1903010
name: regulation of bone development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437]
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060348 ! bone development
relationship: regulates GO:0060348 ! bone development
created_by: mr
creation_date: 2014-05-13T22:41:53Z

[Term]
id: GO:1903011
name: negative regulation of bone development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437]
synonym: "down regulation of bone development" EXACT [GOC:TermGenie]
synonym: "down-regulation of bone development" EXACT [GOC:TermGenie]
synonym: "downregulation of bone development" EXACT [GOC:TermGenie]
synonym: "inhibition of bone development" NARROW [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1903010 ! regulation of bone development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060348 ! bone development
relationship: negatively_regulates GO:0060348 ! bone development
created_by: mr
creation_date: 2014-05-13T22:42:00Z

[Term]
id: GO:1903012
name: positive regulation of bone development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437]
synonym: "activation of bone development" NARROW [GOC:TermGenie]
synonym: "up regulation of bone development" EXACT [GOC:TermGenie]
synonym: "up-regulation of bone development" EXACT [GOC:TermGenie]
synonym: "upregulation of bone development" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1903010 ! regulation of bone development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060348 ! bone development
relationship: positively_regulates GO:0060348 ! bone development
created_by: mr
creation_date: 2014-05-13T22:42:06Z

[Term]
id: GO:1903018
name: regulation of glycoprotein metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079]
comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein
synonym: "regulation of glycoprotein metabolism" EXACT [GOC:TermGenie]
is_a: GO:0060255 ! regulation of macromolecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009100 ! glycoprotein metabolic process
relationship: regulates GO:0009100 ! glycoprotein metabolic process
created_by: rl
creation_date: 2014-05-14T18:44:19Z

[Term]
id: GO:1903019
name: negative regulation of glycoprotein metabolic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079]
comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein
synonym: "down regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie]
synonym: "down regulation of glycoprotein metabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie]
synonym: "downregulation of glycoprotein metabolism" EXACT [GOC:TermGenie]
synonym: "inhibition of glycoprotein metabolic process" NARROW [GOC:TermGenie]
synonym: "inhibition of glycoprotein metabolism" NARROW [GOC:TermGenie]
synonym: "negative regulation of glycoprotein metabolism" EXACT [GOC:TermGenie]
is_a: GO:0010605 ! negative regulation of macromolecule metabolic process
is_a: GO:1903018 ! regulation of glycoprotein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0009100 ! glycoprotein metabolic process
relationship: negatively_regulates GO:0009100 ! glycoprotein metabolic process
created_by: rl
creation_date: 2014-05-14T18:44:25Z

[Term]
id: GO:1903020
name: positive regulation of glycoprotein metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079]
comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein
synonym: "activation of glycoprotein metabolic process" NARROW [GOC:TermGenie]
synonym: "activation of glycoprotein metabolism" NARROW [GOC:TermGenie]
synonym: "positive regulation of glycoprotein metabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie]
synonym: "up regulation of glycoprotein metabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie]
synonym: "upregulation of glycoprotein metabolism" EXACT [GOC:TermGenie]
is_a: GO:0010604 ! positive regulation of macromolecule metabolic process
is_a: GO:1903018 ! regulation of glycoprotein metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009100 ! glycoprotein metabolic process
relationship: positively_regulates GO:0009100 ! glycoprotein metabolic process
created_by: rl
creation_date: 2014-05-14T18:44:31Z

[Term]
id: GO:1903037
name: regulation of leukocyte cell-cell adhesion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532]
comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion
synonym: "regulation of leukocyte adhesion" EXACT [GOC:TermGenie]
synonym: "regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie]
is_a: GO:0022407 ! regulation of cell-cell adhesion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007159 ! leukocyte cell-cell adhesion
relationship: regulates GO:0007159 ! leukocyte cell-cell adhesion
created_by: rl
creation_date: 2014-05-19T15:29:58Z

[Term]
id: GO:1903038
name: negative regulation of leukocyte cell-cell adhesion
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532]
comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion
synonym: "down regulation of leukocyte adhesion" EXACT [GOC:TermGenie]
synonym: "down regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie]
synonym: "down regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie]
synonym: "down-regulation of leukocyte adhesion" EXACT [GOC:TermGenie]
synonym: "down-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie]
synonym: "down-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie]
synonym: "downregulation of leukocyte adhesion" EXACT [GOC:TermGenie]
synonym: "downregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie]
synonym: "downregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie]
synonym: "inhibition of leukocyte adhesion" NARROW [GOC:TermGenie]
synonym: "inhibition of leukocyte cell adhesion" NARROW [GOC:TermGenie]
synonym: "inhibition of leukocyte cell-cell adhesion" NARROW [GOC:TermGenie]
synonym: "negative regulation of leukocyte adhesion" EXACT [GOC:TermGenie]
synonym: "negative regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie]
is_a: GO:0022408 ! negative regulation of cell-cell adhesion
is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007159 ! leukocyte cell-cell adhesion
relationship: negatively_regulates GO:0007159 ! leukocyte cell-cell adhesion
created_by: rl
creation_date: 2014-05-19T15:30:05Z

[Term]
id: GO:1903039
name: positive regulation of leukocyte cell-cell adhesion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532]
comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion
synonym: "activation of leukocyte adhesion" NARROW [GOC:TermGenie]
synonym: "activation of leukocyte cell adhesion" NARROW [GOC:TermGenie]
synonym: "activation of leukocyte cell-cell adhesion" NARROW [GOC:TermGenie]
synonym: "positive regulation of leukocyte adhesion" EXACT [GOC:TermGenie]
synonym: "positive regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie]
synonym: "up regulation of leukocyte adhesion" EXACT [GOC:TermGenie]
synonym: "up regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie]
synonym: "up regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie]
synonym: "up-regulation of leukocyte adhesion" EXACT [GOC:TermGenie]
synonym: "up-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie]
synonym: "up-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie]
synonym: "upregulation of leukocyte adhesion" EXACT [GOC:TermGenie]
synonym: "upregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie]
synonym: "upregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie]
is_a: GO:0022409 ! positive regulation of cell-cell adhesion
is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007159 ! leukocyte cell-cell adhesion
relationship: positively_regulates GO:0007159 ! leukocyte cell-cell adhesion
created_by: rl
creation_date: 2014-05-19T15:30:15Z

[Term]
id: GO:1903045
name: neural crest cell migration involved in sympathetic nervous system development
namespace: biological_process
def: "Any neural crest cell migration that is involved in sympathetic nervous system development." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19325129]
comment: Sema3a (O08665, mouse) is involved in neural crest cell migration involved in sympathetic nervous system development
is_a: GO:1901166 ! neural crest cell migration involved in autonomic nervous system development
intersection_of: GO:0001755 ! neural crest cell migration
intersection_of: part_of GO:0048485 ! sympathetic nervous system development
relationship: part_of GO:0048485 ! sympathetic nervous system development
created_by: rl
creation_date: 2014-05-22T07:06:02Z

[Term]
id: GO:1903046
name: meiotic cell cycle process
namespace: biological_process
def: "A process that is part of the meiotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie]
subset: gocheck_do_not_annotate
subset: goslim_pombe
is_a: GO:0022402 ! cell cycle process
is_a: GO:0022414 ! reproductive process
intersection_of: GO:0009987 ! cellular process
intersection_of: part_of GO:0051321 ! meiotic cell cycle
disjoint_from: GO:1903047 ! mitotic cell cycle process
relationship: part_of GO:0051321 ! meiotic cell cycle
created_by: jl
creation_date: 2014-05-22T14:22:28Z

[Term]
id: GO:1903047
name: mitotic cell cycle process
namespace: biological_process
def: "A process that is part of the mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie]
subset: gocheck_do_not_annotate
is_a: GO:0022402 ! cell cycle process
intersection_of: GO:0009987 ! cellular process
intersection_of: part_of GO:0000278 ! mitotic cell cycle
relationship: part_of GO:0000278 ! mitotic cell cycle
created_by: jl
creation_date: 2014-05-22T14:22:34Z

[Term]
id: GO:1903053
name: regulation of extracellular matrix organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537]
synonym: "regulation of extracellular matrix organisation" EXACT [GOC:TermGenie]
synonym: "regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030198 ! extracellular matrix organization
relationship: regulates GO:0030198 ! extracellular matrix organization
created_by: rl
creation_date: 2014-05-23T17:15:41Z

[Term]
id: GO:1903054
name: negative regulation of extracellular matrix organization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537]
synonym: "down regulation of extracellular matrix organisation" EXACT [GOC:TermGenie]
synonym: "down regulation of extracellular matrix organization" EXACT [GOC:TermGenie]
synonym: "down regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "down-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie]
synonym: "down-regulation of extracellular matrix organization" EXACT [GOC:TermGenie]
synonym: "down-regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "downregulation of extracellular matrix organisation" EXACT [GOC:TermGenie]
synonym: "downregulation of extracellular matrix organization" EXACT [GOC:TermGenie]
synonym: "downregulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "inhibition of extracellular matrix organisation" NARROW [GOC:TermGenie]
synonym: "inhibition of extracellular matrix organization" NARROW [GOC:TermGenie]
synonym: "inhibition of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "negative regulation of extracellular matrix organisation" EXACT [GOC:TermGenie]
synonym: "negative regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0051129 ! negative regulation of cellular component organization
is_a: GO:1903053 ! regulation of extracellular matrix organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030198 ! extracellular matrix organization
relationship: negatively_regulates GO:0030198 ! extracellular matrix organization
created_by: rl
creation_date: 2014-05-23T17:15:47Z

[Term]
id: GO:1903055
name: positive regulation of extracellular matrix organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537]
synonym: "activation of extracellular matrix organisation" NARROW [GOC:TermGenie]
synonym: "activation of extracellular matrix organization" NARROW [GOC:TermGenie]
synonym: "activation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "positive regulation of extracellular matrix organisation" EXACT [GOC:TermGenie]
synonym: "positive regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "up regulation of extracellular matrix organisation" EXACT [GOC:TermGenie]
synonym: "up regulation of extracellular matrix organization" EXACT [GOC:TermGenie]
synonym: "up regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "up-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie]
synonym: "up-regulation of extracellular matrix organization" EXACT [GOC:TermGenie]
synonym: "up-regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "upregulation of extracellular matrix organisation" EXACT [GOC:TermGenie]
synonym: "upregulation of extracellular matrix organization" EXACT [GOC:TermGenie]
synonym: "upregulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0051130 ! positive regulation of cellular component organization
is_a: GO:1903053 ! regulation of extracellular matrix organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030198 ! extracellular matrix organization
relationship: positively_regulates GO:0030198 ! extracellular matrix organization
created_by: rl
creation_date: 2014-05-23T17:15:53Z

[Term]
id: GO:1903076
name: regulation of protein localization to plasma membrane
namespace: biological_process
alt_id: GO:0090003
alt_id: GO:1905963
def: "Any process that modulates the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640]
synonym: "regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah]
synonym: "regulation of establishment of protein localization in plasma membrane" RELATED []
synonym: "regulation of establishment of protein localization to plasma membrane" RELATED []
synonym: "regulation of protein localisation in plasma membrane" RELATED [GOC:TermGenie]
synonym: "regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie]
synonym: "regulation of protein targeting to plasma membrane" RELATED []
synonym: "regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie]
is_a: GO:1904375 ! regulation of protein localization to cell periphery
is_a: GO:1905475 ! regulation of protein localization to membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072659 ! protein localization to plasma membrane
relationship: regulates GO:0072659 ! protein localization to plasma membrane
created_by: tb
creation_date: 2009-07-10T10:32:44Z

[Term]
id: GO:1903077
name: negative regulation of protein localization to plasma membrane
namespace: biological_process
alt_id: GO:0090005
alt_id: GO:1905964
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640]
synonym: "down regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie]
synonym: "down regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie]
synonym: "down regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie]
synonym: "down-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie]
synonym: "down-regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie]
synonym: "downregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie]
synonym: "downregulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie]
synonym: "downregulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie]
synonym: "inhibition of protein localisation in plasma membrane" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization in plasma membrane" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization to plasma membrane" NARROW [GOC:TermGenie]
synonym: "inhibition of protein targeting to plasma membrane" NARROW [GOC:TermGenie]
synonym: "inhibition of protein-plasma membrane targeting" NARROW [GOC:TermGenie]
synonym: "negative regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah]
synonym: "negative regulation of establishment of protein localization in plasma membrane" RELATED []
synonym: "negative regulation of establishment of protein localization to plasma membrane" RELATED []
synonym: "negative regulation of protein localisation in plasma membrane" RELATED [GOC:TermGenie]
synonym: "negative regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein targeting to plasma membrane" RELATED []
synonym: "negative regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie]
is_a: GO:1903076 ! regulation of protein localization to plasma membrane
is_a: GO:1904376 ! negative regulation of protein localization to cell periphery
is_a: GO:1905476 ! negative regulation of protein localization to membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072659 ! protein localization to plasma membrane
relationship: negatively_regulates GO:0072659 ! protein localization to plasma membrane
created_by: tb
creation_date: 2014-05-29T17:10:16Z

[Term]
id: GO:1903078
name: positive regulation of protein localization to plasma membrane
namespace: biological_process
alt_id: GO:0090004
alt_id: GO:1905965
def: "Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640]
synonym: "activation of protein localisation in plasma membrane" NARROW [GOC:TermGenie]
synonym: "activation of protein localization in plasma membrane" NARROW [GOC:TermGenie]
synonym: "activation of protein localization to plasma membrane" NARROW [GOC:TermGenie]
synonym: "activation of protein targeting to plasma membrane" NARROW [GOC:TermGenie]
synonym: "activation of protein-plasma membrane targeting" NARROW [GOC:TermGenie]
synonym: "positive regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah]
synonym: "positive regulation of establishment of protein localization to plasma membrane" RELATED []
synonym: "positive regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein targeting to plasma membrane" RELATED []
synonym: "positive regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie]
synonym: "up regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie]
synonym: "up regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie]
synonym: "up regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie]
synonym: "up-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie]
synonym: "up-regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie]
synonym: "upregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie]
synonym: "upregulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie]
synonym: "upregulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie]
is_a: GO:1903076 ! regulation of protein localization to plasma membrane
is_a: GO:1904377 ! positive regulation of protein localization to cell periphery
is_a: GO:1905477 ! positive regulation of protein localization to membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072659 ! protein localization to plasma membrane
relationship: positively_regulates GO:0072659 ! protein localization to plasma membrane
created_by: tb
creation_date: 2009-07-10T10:34:17Z

[Term]
id: GO:1903115
name: regulation of actin filament-based movement
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735]
is_a: GO:0032970 ! regulation of actin filament-based process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030048 ! actin filament-based movement
relationship: regulates GO:0030048 ! actin filament-based movement
created_by: al
creation_date: 2014-06-12T16:55:57Z

[Term]
id: GO:1903116
name: positive regulation of actin filament-based movement
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735]
synonym: "activation of actin filament-based movement" NARROW [GOC:TermGenie]
synonym: "up regulation of actin filament-based movement" EXACT [GOC:TermGenie]
synonym: "up-regulation of actin filament-based movement" EXACT [GOC:TermGenie]
synonym: "upregulation of actin filament-based movement" EXACT [GOC:TermGenie]
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:1903115 ! regulation of actin filament-based movement
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030048 ! actin filament-based movement
relationship: positively_regulates GO:0030048 ! actin filament-based movement
created_by: al
creation_date: 2014-06-12T16:56:04Z

[Term]
id: GO:1903119
name: protein localization to actin cytoskeleton
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton." [GO_REF:0000087, GOC:TermGenie, PMID:24798735]
synonym: "protein localisation in actin cytoskeleton" EXACT [GOC:TermGenie]
synonym: "protein localisation to actin cytoskeleton" EXACT [GOC:TermGenie]
synonym: "protein localization in actin cytoskeleton" EXACT [GOC:TermGenie]
is_a: GO:0044380 ! protein localization to cytoskeleton
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0015629 ! actin cytoskeleton
relationship: has_target_end_location GO:0015629 ! actin cytoskeleton
created_by: mah
creation_date: 2014-06-16T11:27:09Z

[Term]
id: GO:1903120
name: protein localization to actin filament bundle
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, the location of an actin filament bundle." [GO_REF:0000087, GOC:TermGenie, PMID:24798735]
synonym: "protein localisation in actin filament bundle" EXACT [GOC:TermGenie]
synonym: "protein localisation to actin filament bundle" EXACT [GOC:TermGenie]
synonym: "protein localization in actin filament bundle" EXACT [GOC:TermGenie]
synonym: "protein localization to actin cable" RELATED [GOC:mah]
is_a: GO:1903119 ! protein localization to actin cytoskeleton
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0032432 ! actin filament bundle
relationship: has_target_end_location GO:0032432 ! actin filament bundle
created_by: mah
creation_date: 2014-06-16T11:27:16Z

[Term]
id: GO:1903131
name: mononuclear cell differentiation
namespace: biological_process
def: "The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell." [CL:0000842, GO_REF:0000086, GOC:TermGenie, PMID:24759906]
is_a: GO:0002521 ! leukocyte differentiation
intersection_of: GO:0030154 ! cell differentiation
intersection_of: results_in_acquisition_of_features_of CL:0000842 ! mononuclear cell
relationship: results_in_acquisition_of_features_of CL:0000842 ! mononuclear cell
created_by: cls
creation_date: 2014-06-25T15:47:09Z

[Term]
id: GO:1903224
name: regulation of endodermal cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389]
synonym: "regulation of endoderm cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035987 ! endodermal cell differentiation
relationship: regulates GO:0035987 ! endodermal cell differentiation
created_by: als
creation_date: 2014-07-29T13:22:35Z

[Term]
id: GO:1903225
name: negative regulation of endodermal cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389]
synonym: "down regulation of endoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of endodermal cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of endoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of endodermal cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of endoderm cell differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of endodermal cell differentiation" NARROW [GOC:TermGenie]
synonym: "negative regulation of endoderm cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:1903224 ! regulation of endodermal cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035987 ! endodermal cell differentiation
relationship: negatively_regulates GO:0035987 ! endodermal cell differentiation
created_by: als
creation_date: 2014-07-29T13:22:41Z

[Term]
id: GO:1903226
name: positive regulation of endodermal cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389]
synonym: "activation of endoderm cell differentiation" NARROW [GOC:TermGenie]
synonym: "activation of endodermal cell differentiation" NARROW [GOC:TermGenie]
synonym: "positive regulation of endoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of endoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of endodermal cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of endoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of endodermal cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:1903224 ! regulation of endodermal cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035987 ! endodermal cell differentiation
relationship: positively_regulates GO:0035987 ! endodermal cell differentiation
created_by: als
creation_date: 2014-07-29T13:22:47Z

[Term]
id: GO:1903292
name: protein localization to Golgi membrane
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a Golgi membrane." [GO_REF:0000087, GOC:TermGenie, PMID:11378902]
synonym: "protein localisation in Golgi membrane" EXACT [GOC:TermGenie]
synonym: "protein localisation to Golgi membrane" EXACT [GOC:TermGenie]
synonym: "protein localization in Golgi membrane" EXACT [GOC:TermGenie]
is_a: GO:0034067 ! protein localization to Golgi apparatus
is_a: GO:0072657 ! protein localization to membrane
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0000139 ! Golgi membrane
relationship: has_target_end_location GO:0000139 ! Golgi membrane
created_by: mah
creation_date: 2014-08-12T14:22:31Z

[Term]
id: GO:1903335
name: regulation of vacuolar transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw]
is_a: GO:0032386 ! regulation of intracellular transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007034 ! vacuolar transport
relationship: regulates GO:0007034 ! vacuolar transport
created_by: vw
creation_date: 2014-08-18T13:16:04Z

[Term]
id: GO:1903336
name: negative regulation of vacuolar transport
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw]
synonym: "down regulation of vacuolar transport" EXACT [GOC:TermGenie]
synonym: "down-regulation of vacuolar transport" EXACT [GOC:TermGenie]
synonym: "downregulation of vacuolar transport" EXACT [GOC:TermGenie]
synonym: "inhibition of vacuolar transport" NARROW [GOC:TermGenie]
is_a: GO:0032387 ! negative regulation of intracellular transport
is_a: GO:1903335 ! regulation of vacuolar transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007034 ! vacuolar transport
relationship: negatively_regulates GO:0007034 ! vacuolar transport
created_by: vw
creation_date: 2014-08-18T13:16:11Z

[Term]
id: GO:1903337
name: positive regulation of vacuolar transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw]
synonym: "activation of vacuolar transport" NARROW [GOC:TermGenie]
synonym: "up regulation of vacuolar transport" EXACT [GOC:TermGenie]
synonym: "up-regulation of vacuolar transport" EXACT [GOC:TermGenie]
synonym: "upregulation of vacuolar transport" EXACT [GOC:TermGenie]
is_a: GO:0032388 ! positive regulation of intracellular transport
is_a: GO:1903335 ! regulation of vacuolar transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007034 ! vacuolar transport
relationship: positively_regulates GO:0007034 ! vacuolar transport
created_by: vw
creation_date: 2014-08-18T13:16:19Z

[Term]
id: GO:1903353
name: regulation of nucleus organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of nucleus organization." [GO_REF:0000058, GOC:TermGenie, PMID:16943282]
synonym: "regulation of nuclear morphology" RELATED [GOC:TermGenie]
synonym: "regulation of nuclear organisation" EXACT [GOC:TermGenie]
synonym: "regulation of nuclear organization" EXACT [GOC:TermGenie]
synonym: "regulation of nuclear organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "regulation of nucleus organization and biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0033043 ! regulation of organelle organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006997 ! nucleus organization
relationship: regulates GO:0006997 ! nucleus organization
created_by: hjd
creation_date: 2014-08-20T19:36:16Z

[Term]
id: GO:1903358
name: regulation of Golgi organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of Golgi organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:17562788]
synonym: "regulation of Golgi organisation" EXACT [GOC:TermGenie]
synonym: "regulation of Golgi organization and biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0033043 ! regulation of organelle organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007030 ! Golgi organization
relationship: regulates GO:0007030 ! Golgi organization
created_by: als
creation_date: 2014-08-21T10:22:22Z

[Term]
id: GO:1903379
name: regulation of mitotic chromosome condensation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640]
is_a: GO:0010564 ! regulation of cell cycle process
is_a: GO:0060623 ! regulation of chromosome condensation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007076 ! mitotic chromosome condensation
relationship: regulates GO:0007076 ! mitotic chromosome condensation
created_by: al
creation_date: 2014-08-26T13:57:13Z

[Term]
id: GO:1903380
name: positive regulation of mitotic chromosome condensation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640]
synonym: "activation of mitotic chromosome condensation" NARROW [GOC:TermGenie]
synonym: "up regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie]
synonym: "up-regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie]
synonym: "upregulation of mitotic chromosome condensation" EXACT [GOC:TermGenie]
is_a: GO:0090068 ! positive regulation of cell cycle process
is_a: GO:1903379 ! regulation of mitotic chromosome condensation
is_a: GO:1905821 ! positive regulation of chromosome condensation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007076 ! mitotic chromosome condensation
relationship: positively_regulates GO:0007076 ! mitotic chromosome condensation
created_by: al
creation_date: 2014-08-26T13:57:29Z

[Term]
id: GO:1903412
name: response to bile acid
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus." [GO_REF:0000071, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21757002]
is_a: GO:0014070 ! response to organic cyclic compound
is_a: GO:0033993 ! response to lipid
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:3098 ! bile acid
relationship: has_primary_input CHEBI:3098 ! bile acid
created_by: rl
creation_date: 2014-09-03T12:45:43Z

[Term]
id: GO:1903429
name: regulation of cell maturation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944]
synonym: "regulation of functional differentiation" RELATED [GOC:TermGenie]
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048469 ! cell maturation
relationship: regulates GO:0048469 ! cell maturation
created_by: jl
creation_date: 2014-09-15T13:31:23Z

[Term]
id: GO:1903430
name: negative regulation of cell maturation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944]
synonym: "down regulation of cell maturation" EXACT [GOC:TermGenie]
synonym: "down regulation of functional differentiation" RELATED [GOC:TermGenie]
synonym: "down-regulation of cell maturation" EXACT [GOC:TermGenie]
synonym: "down-regulation of functional differentiation" RELATED [GOC:TermGenie]
synonym: "downregulation of cell maturation" EXACT [GOC:TermGenie]
synonym: "downregulation of functional differentiation" RELATED [GOC:TermGenie]
synonym: "inhibition of cell maturation" NARROW [GOC:TermGenie]
synonym: "inhibition of functional differentiation" RELATED [GOC:TermGenie]
synonym: "negative regulation of functional differentiation" RELATED [GOC:TermGenie]
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:1903429 ! regulation of cell maturation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048469 ! cell maturation
relationship: negatively_regulates GO:0048469 ! cell maturation
created_by: jl
creation_date: 2014-09-15T13:31:32Z

[Term]
id: GO:1903431
name: positive regulation of cell maturation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944]
synonym: "activation of cell maturation" NARROW [GOC:TermGenie]
synonym: "activation of functional differentiation" RELATED [GOC:TermGenie]
synonym: "positive regulation of functional differentiation" RELATED [GOC:TermGenie]
synonym: "up regulation of cell maturation" EXACT [GOC:TermGenie]
synonym: "up regulation of functional differentiation" RELATED [GOC:TermGenie]
synonym: "up-regulation of cell maturation" EXACT [GOC:TermGenie]
synonym: "up-regulation of functional differentiation" RELATED [GOC:TermGenie]
synonym: "upregulation of cell maturation" EXACT [GOC:TermGenie]
synonym: "upregulation of functional differentiation" RELATED [GOC:TermGenie]
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:1903429 ! regulation of cell maturation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048469 ! cell maturation
relationship: positively_regulates GO:0048469 ! cell maturation
created_by: jl
creation_date: 2014-09-15T13:31:41Z

[Term]
id: GO:1903441
name: protein localization to ciliary membrane
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a ciliary membrane." [GO_REF:0000087, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22139371]
synonym: "protein localisation in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "protein localisation to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "protein localization in ciliary membrane" EXACT [GOC:TermGenie]
is_a: GO:0061512 ! protein localization to cilium
is_a: GO:0072657 ! protein localization to membrane
is_a: GO:1990778 ! protein localization to cell periphery
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0060170 ! ciliary membrane
relationship: has_target_end_location GO:0060170 ! ciliary membrane
created_by: pr
creation_date: 2014-09-16T15:15:39Z

[Term]
id: GO:1903510
name: mucopolysaccharide metabolic process
namespace: biological_process
def: "The chemical reactions and pathways involving mucopolysaccharide." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:4236091]
synonym: "mucopolysaccharide metabolism" EXACT [GOC:TermGenie]
is_a: GO:0030203 ! glycosaminoglycan metabolic process
intersection_of: GO:0008152 ! metabolic process
intersection_of: has_primary_input_or_output CHEBI:37395 ! mucopolysaccharide
relationship: has_primary_input_or_output CHEBI:37395 ! mucopolysaccharide
created_by: dph
creation_date: 2014-10-01T21:55:47Z

[Term]
id: GO:1903522
name: regulation of blood circulation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969]
synonym: "regulation of hemolymph circulation" RELATED [GOC:TermGenie]
is_a: GO:0044057 ! regulation of system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008015 ! blood circulation
relationship: regulates GO:0008015 ! blood circulation
created_by: mr
creation_date: 2014-10-06T18:38:56Z

[Term]
id: GO:1903523
name: negative regulation of blood circulation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969]
synonym: "down regulation of blood circulation" EXACT [GOC:TermGenie]
synonym: "down regulation of hemolymph circulation" RELATED [GOC:TermGenie]
synonym: "down-regulation of blood circulation" EXACT [GOC:TermGenie]
synonym: "down-regulation of hemolymph circulation" RELATED [GOC:TermGenie]
synonym: "downregulation of blood circulation" EXACT [GOC:TermGenie]
synonym: "downregulation of hemolymph circulation" RELATED [GOC:TermGenie]
synonym: "inhibition of blood circulation" NARROW [GOC:TermGenie]
synonym: "inhibition of hemolymph circulation" RELATED [GOC:TermGenie]
synonym: "negative regulation of hemolymph circulation" RELATED [GOC:TermGenie]
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1903522 ! regulation of blood circulation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008015 ! blood circulation
relationship: negatively_regulates GO:0008015 ! blood circulation
created_by: mr
creation_date: 2014-10-06T18:39:05Z

[Term]
id: GO:1903524
name: positive regulation of blood circulation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969]
synonym: "activation of blood circulation" NARROW [GOC:TermGenie]
synonym: "activation of hemolymph circulation" RELATED [GOC:TermGenie]
synonym: "positive regulation of hemolymph circulation" RELATED [GOC:TermGenie]
synonym: "up regulation of blood circulation" EXACT [GOC:TermGenie]
synonym: "up regulation of hemolymph circulation" RELATED [GOC:TermGenie]
synonym: "up-regulation of blood circulation" EXACT [GOC:TermGenie]
synonym: "up-regulation of hemolymph circulation" RELATED [GOC:TermGenie]
synonym: "upregulation of blood circulation" EXACT [GOC:TermGenie]
synonym: "upregulation of hemolymph circulation" RELATED [GOC:TermGenie]
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1903522 ! regulation of blood circulation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008015 ! blood circulation
relationship: positively_regulates GO:0008015 ! blood circulation
created_by: mr
creation_date: 2014-10-06T18:39:13Z

[Term]
id: GO:1903530
name: regulation of secretion by cell
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530]
synonym: "regulation of cellular secretion" EXACT [GOC:TermGenie]
is_a: GO:0050794 ! regulation of cellular process
is_a: GO:0051046 ! regulation of secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032940 ! secretion by cell
relationship: regulates GO:0032940 ! secretion by cell
created_by: pm
creation_date: 2014-10-08T13:24:59Z

[Term]
id: GO:1903531
name: negative regulation of secretion by cell
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530]
synonym: "down regulation of cellular secretion" EXACT [GOC:TermGenie]
synonym: "down regulation of secretion by cell" EXACT [GOC:TermGenie]
synonym: "down-regulation of cellular secretion" EXACT [GOC:TermGenie]
synonym: "down-regulation of secretion by cell" EXACT [GOC:TermGenie]
synonym: "downregulation of cellular secretion" EXACT [GOC:TermGenie]
synonym: "downregulation of secretion by cell" EXACT [GOC:TermGenie]
synonym: "inhibition of cellular secretion" NARROW [GOC:TermGenie]
synonym: "inhibition of secretion by cell" NARROW [GOC:TermGenie]
synonym: "negative regulation of cellular secretion" EXACT [GOC:TermGenie]
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:0051048 ! negative regulation of secretion
is_a: GO:1903530 ! regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032940 ! secretion by cell
relationship: negatively_regulates GO:0032940 ! secretion by cell
created_by: pm
creation_date: 2014-10-08T13:25:08Z

[Term]
id: GO:1903532
name: positive regulation of secretion by cell
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530]
synonym: "activation of cellular secretion" NARROW [GOC:TermGenie]
synonym: "activation of secretion by cell" NARROW [GOC:TermGenie]
synonym: "positive regulation of cellular secretion" EXACT [GOC:TermGenie]
synonym: "up regulation of cellular secretion" EXACT [GOC:TermGenie]
synonym: "up regulation of secretion by cell" EXACT [GOC:TermGenie]
synonym: "up-regulation of cellular secretion" EXACT [GOC:TermGenie]
synonym: "up-regulation of secretion by cell" EXACT [GOC:TermGenie]
synonym: "upregulation of cellular secretion" EXACT [GOC:TermGenie]
synonym: "upregulation of secretion by cell" EXACT [GOC:TermGenie]
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:0051047 ! positive regulation of secretion
is_a: GO:1903530 ! regulation of secretion by cell
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032940 ! secretion by cell
relationship: positively_regulates GO:0032940 ! secretion by cell
created_by: pm
creation_date: 2014-10-08T13:25:17Z

[Term]
id: GO:1903537
name: meiotic cell cycle process involved in oocyte maturation
namespace: biological_process
def: "Any meiotic cell cycle process that is involved in oocyte maturation." [GO_REF:0000060, GOC:jz, GOC:TermGenie, PMID:25212395]
synonym: "meiosis involved in oocyte maturation" BROAD []
is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism
is_a: GO:1903046 ! meiotic cell cycle process
intersection_of: GO:1903046 ! meiotic cell cycle process
intersection_of: part_of GO:0001556 ! oocyte maturation
relationship: part_of GO:0001556 ! oocyte maturation
created_by: pr
creation_date: 2014-10-09T10:46:14Z

[Term]
id: GO:1903538
name: regulation of meiotic cell cycle process involved in oocyte maturation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:jz, GOC:TermGenie, PMID:25212395]
synonym: "regulation of meiosis involved in oocyte maturation" BROAD [GOC:TermGenie]
is_a: GO:0010564 ! regulation of cell cycle process
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation
relationship: regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation
created_by: pr
creation_date: 2014-10-09T10:52:38Z

[Term]
id: GO:1903541
name: regulation of exosomal secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262]
synonym: "regulation of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "regulation of exosomal secretory pathway" EXACT [GOC:TermGenie]
synonym: "regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie]
synonym: "regulation of secretion of exosome" EXACT [GOC:TermGenie]
is_a: GO:0017157 ! regulation of exocytosis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1990182 ! exosomal secretion
relationship: regulates GO:1990182 ! exosomal secretion
created_by: pga
creation_date: 2014-10-14T11:38:52Z

[Term]
id: GO:1903542
name: negative regulation of exosomal secretion
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262]
synonym: "down regulation of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "down regulation of exosomal secretion" EXACT [GOC:TermGenie]
synonym: "down regulation of exosomal secretory pathway" EXACT [GOC:TermGenie]
synonym: "down regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie]
synonym: "down regulation of secretion of exosome" EXACT [GOC:TermGenie]
synonym: "down-regulation of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "down-regulation of exosomal secretion" EXACT [GOC:TermGenie]
synonym: "down-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie]
synonym: "down-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie]
synonym: "down-regulation of secretion of exosome" EXACT [GOC:TermGenie]
synonym: "downregulation of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "downregulation of exosomal secretion" EXACT [GOC:TermGenie]
synonym: "downregulation of exosomal secretory pathway" EXACT [GOC:TermGenie]
synonym: "downregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie]
synonym: "downregulation of secretion of exosome" EXACT [GOC:TermGenie]
synonym: "inhibition of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "inhibition of exosomal secretion" NARROW [GOC:TermGenie]
synonym: "inhibition of exosomal secretory pathway" NARROW [GOC:TermGenie]
synonym: "inhibition of extracellular vesicular exosome secretion" NARROW [GOC:TermGenie]
synonym: "inhibition of secretion of exosome" NARROW [GOC:TermGenie]
synonym: "negative regulation of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "negative regulation of exosomal secretory pathway" EXACT [GOC:TermGenie]
synonym: "negative regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie]
synonym: "negative regulation of secretion of exosome" EXACT [GOC:TermGenie]
is_a: GO:0045920 ! negative regulation of exocytosis
is_a: GO:1903541 ! regulation of exosomal secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1990182 ! exosomal secretion
relationship: negatively_regulates GO:1990182 ! exosomal secretion
created_by: pga
creation_date: 2014-10-14T11:39:02Z

[Term]
id: GO:1903543
name: positive regulation of exosomal secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262]
synonym: "activation of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "activation of exosomal secretion" NARROW [GOC:TermGenie]
synonym: "activation of exosomal secretory pathway" NARROW [GOC:TermGenie]
synonym: "activation of extracellular vesicular exosome secretion" NARROW [GOC:TermGenie]
synonym: "activation of secretion of exosome" NARROW [GOC:TermGenie]
synonym: "positive regulation of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "positive regulation of exosomal secretory pathway" EXACT [GOC:TermGenie]
synonym: "positive regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie]
synonym: "positive regulation of secretion of exosome" EXACT [GOC:TermGenie]
synonym: "up regulation of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "up regulation of exosomal secretion" EXACT [GOC:TermGenie]
synonym: "up regulation of exosomal secretory pathway" EXACT [GOC:TermGenie]
synonym: "up regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie]
synonym: "up regulation of secretion of exosome" EXACT [GOC:TermGenie]
synonym: "up-regulation of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "up-regulation of exosomal secretion" EXACT [GOC:TermGenie]
synonym: "up-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie]
synonym: "up-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie]
synonym: "up-regulation of secretion of exosome" EXACT [GOC:TermGenie]
synonym: "upregulation of exosomal protein secretion" NARROW [GOC:TermGenie]
synonym: "upregulation of exosomal secretion" EXACT [GOC:TermGenie]
synonym: "upregulation of exosomal secretory pathway" EXACT [GOC:TermGenie]
synonym: "upregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie]
synonym: "upregulation of secretion of exosome" EXACT [GOC:TermGenie]
is_a: GO:0044089 ! positive regulation of cellular component biogenesis
is_a: GO:0045921 ! positive regulation of exocytosis
is_a: GO:1903541 ! regulation of exosomal secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1990182 ! exosomal secretion
relationship: positively_regulates GO:1990182 ! exosomal secretion
created_by: pga
creation_date: 2014-10-14T11:39:10Z

[Term]
id: GO:1903551
name: regulation of extracellular exosome assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262]
synonym: "regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles]
is_a: GO:1902115 ! regulation of organelle assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0071971 ! extracellular exosome assembly
relationship: regulates GO:0071971 ! extracellular exosome assembly
created_by: pga
creation_date: 2014-10-20T15:37:25Z

[Term]
id: GO:1903552
name: negative regulation of extracellular exosome assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262]
synonym: "down regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie]
synonym: "inhibition of extracellular vesicular exosome assembly" NARROW [GOC:TermGenie]
synonym: "negative regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles]
is_a: GO:1902116 ! negative regulation of organelle assembly
is_a: GO:1903551 ! regulation of extracellular exosome assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0071971 ! extracellular exosome assembly
relationship: negatively_regulates GO:0071971 ! extracellular exosome assembly
created_by: pga
creation_date: 2014-10-20T15:37:33Z

[Term]
id: GO:1903553
name: positive regulation of extracellular exosome assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262]
synonym: "activation of extracellular vesicular exosome assembly" NARROW [GOC:TermGenie]
synonym: "positive regulation of extracellular vesicular exosome assembly" RELATED [GOC:vesicles]
synonym: "up regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie]
is_a: GO:1902117 ! positive regulation of organelle assembly
is_a: GO:1903551 ! regulation of extracellular exosome assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0071971 ! extracellular exosome assembly
relationship: positively_regulates GO:0071971 ! extracellular exosome assembly
created_by: pga
creation_date: 2014-10-20T15:37:42Z

[Term]
id: GO:1903561
name: extracellular vesicle
namespace: cellular_component
def: "Any vesicle that is part of the extracellular region." [GO_REF:0000064, GOC:pm, GOC:TermGenie, PMID:24769233]
synonym: "microparticle" RELATED [GOC:vesicles]
is_a: GO:0031982 ! vesicle
is_a: GO:0065010 ! extracellular membrane-bounded organelle
intersection_of: GO:0031982 ! vesicle
intersection_of: part_of GO:0005576 ! extracellular region
created_by: jl
creation_date: 2014-10-22T14:26:11Z

[Term]
id: GO:1903564
name: regulation of protein localization to cilium
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986]
is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061512 ! protein localization to cilium
relationship: regulates GO:0061512 ! protein localization to cilium
created_by: krc
creation_date: 2014-10-24T20:58:11Z

[Term]
id: GO:1903565
name: negative regulation of protein localization to cilium
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986]
synonym: "down regulation of protein localization to cilium" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to cilium" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to cilium" EXACT [GOC:TermGenie]
synonym: "inhibition of protein localization to cilium" NARROW [GOC:TermGenie]
is_a: GO:1903564 ! regulation of protein localization to cilium
is_a: GO:1903828 ! negative regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061512 ! protein localization to cilium
relationship: negatively_regulates GO:0061512 ! protein localization to cilium
created_by: krc
creation_date: 2014-10-24T20:58:20Z

[Term]
id: GO:1903566
name: positive regulation of protein localization to cilium
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986]
synonym: "activation of protein localization to cilium" NARROW [GOC:TermGenie]
synonym: "up regulation of protein localization to cilium" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to cilium" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to cilium" EXACT [GOC:TermGenie]
is_a: GO:1903564 ! regulation of protein localization to cilium
is_a: GO:1903829 ! positive regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061512 ! protein localization to cilium
relationship: positively_regulates GO:0061512 ! protein localization to cilium
created_by: krc
creation_date: 2014-10-24T20:58:28Z

[Term]
id: GO:1903567
name: regulation of protein localization to ciliary membrane
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986]
synonym: "regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie]
is_a: GO:1903564 ! regulation of protein localization to cilium
is_a: GO:1904375 ! regulation of protein localization to cell periphery
is_a: GO:1905475 ! regulation of protein localization to membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1903441 ! protein localization to ciliary membrane
relationship: regulates GO:1903441 ! protein localization to ciliary membrane
created_by: krc
creation_date: 2014-10-24T21:32:51Z

[Term]
id: GO:1903568
name: negative regulation of protein localization to ciliary membrane
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986]
synonym: "down regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "inhibition of protein localisation in ciliary membrane" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localisation to ciliary membrane" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization in ciliary membrane" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization to ciliary membrane" NARROW [GOC:TermGenie]
synonym: "negative regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie]
is_a: GO:1903565 ! negative regulation of protein localization to cilium
is_a: GO:1903567 ! regulation of protein localization to ciliary membrane
is_a: GO:1904376 ! negative regulation of protein localization to cell periphery
is_a: GO:1905476 ! negative regulation of protein localization to membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1903441 ! protein localization to ciliary membrane
relationship: negatively_regulates GO:1903441 ! protein localization to ciliary membrane
created_by: krc
creation_date: 2014-10-24T21:32:59Z

[Term]
id: GO:1903569
name: positive regulation of protein localization to ciliary membrane
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986]
synonym: "activation of protein localisation in ciliary membrane" NARROW [GOC:TermGenie]
synonym: "activation of protein localisation to ciliary membrane" NARROW [GOC:TermGenie]
synonym: "activation of protein localization in ciliary membrane" NARROW [GOC:TermGenie]
synonym: "activation of protein localization to ciliary membrane" NARROW [GOC:TermGenie]
synonym: "positive regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie]
is_a: GO:1903566 ! positive regulation of protein localization to cilium
is_a: GO:1903567 ! regulation of protein localization to ciliary membrane
is_a: GO:1904377 ! positive regulation of protein localization to cell periphery
is_a: GO:1905477 ! positive regulation of protein localization to membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1903441 ! protein localization to ciliary membrane
relationship: positively_regulates GO:1903441 ! protein localization to ciliary membrane
created_by: krc
creation_date: 2014-10-24T21:33:08Z

[Term]
id: GO:1903624
name: regulation of DNA catabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740]
synonym: "regulation of DNA breakdown" EXACT [GOC:TermGenie]
synonym: "regulation of DNA catabolism" EXACT [GOC:TermGenie]
synonym: "regulation of DNA degradation" EXACT [GOC:TermGenie]
is_a: GO:0031329 ! regulation of cellular catabolic process
is_a: GO:0051052 ! regulation of DNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0006308 ! DNA catabolic process
relationship: regulates GO:0006308 ! DNA catabolic process
created_by: sl
creation_date: 2014-11-19T22:36:35Z

[Term]
id: GO:1903625
name: negative regulation of DNA catabolic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740]
synonym: "down regulation of DNA breakdown" EXACT [GOC:TermGenie]
synonym: "down regulation of DNA catabolic process" EXACT [GOC:TermGenie]
synonym: "down regulation of DNA catabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of DNA degradation" EXACT [GOC:TermGenie]
synonym: "down-regulation of DNA breakdown" EXACT [GOC:TermGenie]
synonym: "down-regulation of DNA catabolic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of DNA catabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of DNA degradation" EXACT [GOC:TermGenie]
synonym: "downregulation of DNA breakdown" EXACT [GOC:TermGenie]
synonym: "downregulation of DNA catabolic process" EXACT [GOC:TermGenie]
synonym: "downregulation of DNA catabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of DNA degradation" EXACT [GOC:TermGenie]
synonym: "inhibition of DNA breakdown" NARROW [GOC:TermGenie]
synonym: "inhibition of DNA catabolic process" NARROW [GOC:TermGenie]
synonym: "inhibition of DNA catabolism" NARROW [GOC:TermGenie]
synonym: "inhibition of DNA degradation" NARROW [GOC:TermGenie]
synonym: "negative regulation of DNA breakdown" EXACT [GOC:TermGenie]
synonym: "negative regulation of DNA catabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of DNA degradation" EXACT [GOC:TermGenie]
is_a: GO:0031330 ! negative regulation of cellular catabolic process
is_a: GO:0051053 ! negative regulation of DNA metabolic process
is_a: GO:1903624 ! regulation of DNA catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006308 ! DNA catabolic process
relationship: negatively_regulates GO:0006308 ! DNA catabolic process
created_by: sl
creation_date: 2014-11-19T22:36:43Z

[Term]
id: GO:1903626
name: positive regulation of DNA catabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740]
synonym: "activation of DNA breakdown" NARROW [GOC:TermGenie]
synonym: "activation of DNA catabolic process" NARROW [GOC:TermGenie]
synonym: "activation of DNA catabolism" NARROW [GOC:TermGenie]
synonym: "activation of DNA degradation" NARROW [GOC:TermGenie]
synonym: "positive regulation of DNA breakdown" EXACT [GOC:TermGenie]
synonym: "positive regulation of DNA catabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of DNA degradation" EXACT [GOC:TermGenie]
synonym: "up regulation of DNA breakdown" EXACT [GOC:TermGenie]
synonym: "up regulation of DNA catabolic process" EXACT [GOC:TermGenie]
synonym: "up regulation of DNA catabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of DNA degradation" EXACT [GOC:TermGenie]
synonym: "up-regulation of DNA breakdown" EXACT [GOC:TermGenie]
synonym: "up-regulation of DNA catabolic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of DNA catabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of DNA degradation" EXACT [GOC:TermGenie]
synonym: "upregulation of DNA breakdown" EXACT [GOC:TermGenie]
synonym: "upregulation of DNA catabolic process" EXACT [GOC:TermGenie]
synonym: "upregulation of DNA catabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of DNA degradation" EXACT [GOC:TermGenie]
is_a: GO:0031331 ! positive regulation of cellular catabolic process
is_a: GO:0051054 ! positive regulation of DNA metabolic process
is_a: GO:1903624 ! regulation of DNA catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006308 ! DNA catabolic process
relationship: positively_regulates GO:0006308 ! DNA catabolic process
created_by: sl
creation_date: 2014-11-19T22:36:51Z

[Term]
id: GO:1903697
name: negative regulation of microvillus assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597]
synonym: "down regulation of microvillus assembly" EXACT [GOC:TermGenie]
synonym: "down regulation of microvillus biogenesis" RELATED [GOC:TermGenie]
synonym: "down-regulation of microvillus assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of microvillus biogenesis" RELATED [GOC:TermGenie]
synonym: "downregulation of microvillus assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of microvillus biogenesis" RELATED [GOC:TermGenie]
synonym: "inhibition of microvillus assembly" NARROW [GOC:TermGenie]
synonym: "inhibition of microvillus biogenesis" RELATED [GOC:TermGenie]
synonym: "negative regulation of microvillus biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0032534 ! regulation of microvillus assembly
is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030033 ! microvillus assembly
relationship: negatively_regulates GO:0030033 ! microvillus assembly
created_by: als
creation_date: 2014-12-03T11:45:08Z

[Term]
id: GO:1903698
name: positive regulation of microvillus assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597]
synonym: "activation of microvillus assembly" NARROW [GOC:TermGenie]
synonym: "activation of microvillus biogenesis" RELATED [GOC:TermGenie]
synonym: "positive regulation of microvillus biogenesis" RELATED [GOC:TermGenie]
synonym: "up regulation of microvillus assembly" EXACT [GOC:TermGenie]
synonym: "up regulation of microvillus biogenesis" RELATED [GOC:TermGenie]
synonym: "up-regulation of microvillus assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of microvillus biogenesis" RELATED [GOC:TermGenie]
synonym: "upregulation of microvillus assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of microvillus biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0032534 ! regulation of microvillus assembly
is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030033 ! microvillus assembly
relationship: positively_regulates GO:0030033 ! microvillus assembly
created_by: als
creation_date: 2014-12-03T11:45:17Z

[Term]
id: GO:1903701
name: substantia propria of cornea development
namespace: biological_process
def: "The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12556382]
synonym: "corneal stroma development" EXACT [GOC:TermGenie]
synonym: "stroma of cornea development" EXACT [GOC:TermGenie]
synonym: "substantia propria development" RELATED [GOC:TermGenie]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001777 ! substantia propria of cornea
relationship: results_in_development_of UBERON:0001777 ! substantia propria of cornea
created_by: cls
creation_date: 2014-12-03T13:12:09Z

[Term]
id: GO:1903702
name: esophagus development
namespace: biological_process
def: "The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0-683-40008-8]
synonym: "esophageal development" EXACT [MGI:csmith]
synonym: "gullet development" EXACT [GOC:TermGenie]
synonym: "oesophagus development" EXACT [GOC:TermGenie]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001043 ! esophagus
relationship: results_in_development_of UBERON:0001043 ! esophagus
created_by: cls
creation_date: 2014-12-03T14:41:30Z

[Term]
id: GO:1903706
name: regulation of hemopoiesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761]
comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.
synonym: "regulation of blood cell biosynthesis" EXACT [GOC:TermGenie]
synonym: "regulation of blood cell formation" EXACT [GOC:TermGenie]
synonym: "regulation of haemopoiesis" EXACT [GOC:TermGenie]
synonym: "regulation of hematopoiesis" EXACT [GOC:TermGenie]
is_a: GO:0002682 ! regulation of immune system process
is_a: GO:0060284 ! regulation of cell development
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030097 ! hemopoiesis
relationship: regulates GO:0030097 ! hemopoiesis
created_by: pad
creation_date: 2014-12-04T15:34:13Z

[Term]
id: GO:1903707
name: negative regulation of hemopoiesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761]
comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.
synonym: "down regulation of blood cell biosynthesis" EXACT [GOC:TermGenie]
synonym: "down regulation of blood cell formation" EXACT [GOC:TermGenie]
synonym: "down regulation of haemopoiesis" EXACT [GOC:TermGenie]
synonym: "down regulation of hematopoiesis" EXACT [GOC:TermGenie]
synonym: "down regulation of hemopoiesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of blood cell formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of haemopoiesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of hematopoiesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of hemopoiesis" EXACT [GOC:TermGenie]
synonym: "downregulation of blood cell biosynthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of blood cell formation" EXACT [GOC:TermGenie]
synonym: "downregulation of haemopoiesis" EXACT [GOC:TermGenie]
synonym: "downregulation of hematopoiesis" EXACT [GOC:TermGenie]
synonym: "downregulation of hemopoiesis" EXACT [GOC:TermGenie]
synonym: "inhibition of blood cell biosynthesis" NARROW [GOC:TermGenie]
synonym: "inhibition of blood cell formation" NARROW [GOC:TermGenie]
synonym: "inhibition of haemopoiesis" NARROW [GOC:TermGenie]
synonym: "inhibition of hematopoiesis" NARROW [GOC:TermGenie]
synonym: "inhibition of hemopoiesis" NARROW [GOC:TermGenie]
synonym: "negative regulation of blood cell biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of blood cell formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of haemopoiesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of hematopoiesis" EXACT [GOC:TermGenie]
is_a: GO:0002683 ! negative regulation of immune system process
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1903706 ! regulation of hemopoiesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030097 ! hemopoiesis
relationship: negatively_regulates GO:0030097 ! hemopoiesis
created_by: pad
creation_date: 2014-12-04T15:34:21Z

[Term]
id: GO:1903708
name: positive regulation of hemopoiesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761]
comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.
synonym: "activation of blood cell biosynthesis" NARROW [GOC:TermGenie]
synonym: "activation of blood cell formation" NARROW [GOC:TermGenie]
synonym: "activation of haemopoiesis" NARROW [GOC:TermGenie]
synonym: "activation of hematopoiesis" NARROW [GOC:TermGenie]
synonym: "activation of hemopoiesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of blood cell biosynthesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of blood cell formation" EXACT [GOC:TermGenie]
synonym: "positive regulation of haemopoiesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of hematopoiesis" EXACT [GOC:TermGenie]
synonym: "up regulation of blood cell biosynthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of blood cell formation" EXACT [GOC:TermGenie]
synonym: "up regulation of haemopoiesis" EXACT [GOC:TermGenie]
synonym: "up regulation of hematopoiesis" EXACT [GOC:TermGenie]
synonym: "up regulation of hemopoiesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of blood cell formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of haemopoiesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of hematopoiesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of hemopoiesis" EXACT [GOC:TermGenie]
synonym: "upregulation of blood cell biosynthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of blood cell formation" EXACT [GOC:TermGenie]
synonym: "upregulation of haemopoiesis" EXACT [GOC:TermGenie]
synonym: "upregulation of hematopoiesis" EXACT [GOC:TermGenie]
synonym: "upregulation of hemopoiesis" EXACT [GOC:TermGenie]
is_a: GO:0002684 ! positive regulation of immune system process
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1903706 ! regulation of hemopoiesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030097 ! hemopoiesis
relationship: positively_regulates GO:0030097 ! hemopoiesis
created_by: pad
creation_date: 2014-12-04T15:34:30Z

[Term]
id: GO:1903709
name: uterine gland development
namespace: biological_process
def: "The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:23619340]
synonym: "endometrial gland development" EXACT [GOC:TermGenie]
synonym: "endometrium gland development" EXACT [GOC:TermGenie]
synonym: "glandulae uterinae development" RELATED [GOC:TermGenie]
synonym: "glandular part of endometrium development" RELATED [GOC:TermGenie]
synonym: "set of uterine glands development" RELATED [GOC:TermGenie]
synonym: "uterine glands development" EXACT [GOC:TermGenie]
synonym: "uterine glands set development" EXACT [GOC:TermGenie]
is_a: GO:0048732 ! gland development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002451 ! endometrial gland
relationship: results_in_development_of UBERON:0002451 ! endometrial gland
created_by: cls
creation_date: 2014-12-04T18:57:21Z

[Term]
id: GO:1903729
name: regulation of plasma membrane organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of plasma membrane organization." [GO_REF:0000058, GOC:TermGenie, PMID:24514900]
synonym: "regulation of plasma membrane organisation" EXACT [GOC:TermGenie]
synonym: "regulation of plasma membrane organization and biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007009 ! plasma membrane organization
relationship: regulates GO:0007009 ! plasma membrane organization
created_by: al
creation_date: 2014-12-10T18:59:44Z

[Term]
id: GO:1903778
name: protein localization to vacuolar membrane
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane." [GO_REF:0000087, GOC:TermGenie, PMID:25378562]
synonym: "protein localisation in vacuolar membrane" EXACT [GOC:TermGenie]
synonym: "protein localisation to vacuolar membrane" EXACT [GOC:TermGenie]
synonym: "protein localization in vacuolar membrane" EXACT [GOC:TermGenie]
is_a: GO:0072657 ! protein localization to membrane
is_a: GO:0072665 ! protein localization to vacuole
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005774 ! vacuolar membrane
relationship: has_target_end_location GO:0005774 ! vacuolar membrane
created_by: mah
creation_date: 2015-01-07T13:15:54Z

[Term]
id: GO:1903779
name: regulation of cardiac conduction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627]
is_a: GO:0008016 ! regulation of heart contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061337 ! cardiac conduction
relationship: regulates GO:0061337 ! cardiac conduction
created_by: rph
creation_date: 2015-01-07T13:20:11Z

[Term]
id: GO:1903780
name: negative regulation of cardiac conduction
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627]
synonym: "down regulation of cardiac conduction" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiac conduction" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiac conduction" EXACT [GOC:TermGenie]
synonym: "inhibition of cardiac conduction" NARROW [GOC:TermGenie]
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:1903779 ! regulation of cardiac conduction
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061337 ! cardiac conduction
relationship: negatively_regulates GO:0061337 ! cardiac conduction
created_by: rph
creation_date: 2015-01-07T13:20:20Z

[Term]
id: GO:1903781
name: positive regulation of cardiac conduction
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627]
synonym: "activation of cardiac conduction" NARROW [GOC:TermGenie]
synonym: "up regulation of cardiac conduction" EXACT [GOC:TermGenie]
synonym: "up-regulation of cardiac conduction" EXACT [GOC:TermGenie]
synonym: "upregulation of cardiac conduction" EXACT [GOC:TermGenie]
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:1903779 ! regulation of cardiac conduction
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061337 ! cardiac conduction
relationship: positively_regulates GO:0061337 ! cardiac conduction
created_by: rph
creation_date: 2015-01-07T13:20:28Z

[Term]
id: GO:1903789
name: regulation of amino acid transmembrane transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of amino acid transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:16115814]
synonym: "regulation of amino acid membrane transport" EXACT [GOC:TermGenie]
is_a: GO:0034762 ! regulation of transmembrane transport
is_a: GO:0051955 ! regulation of amino acid transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003333 ! amino acid transmembrane transport
relationship: regulates GO:0003333 ! amino acid transmembrane transport
created_by: al
creation_date: 2015-01-08T17:42:18Z

[Term]
id: GO:1903795
name: regulation of inorganic anion transmembrane transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802]
synonym: "regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie]
synonym: "regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie]
is_a: GO:0034762 ! regulation of transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0098661 ! inorganic anion transmembrane transport
relationship: regulates GO:0098661 ! inorganic anion transmembrane transport
created_by: sl
creation_date: 2015-01-14T21:44:49Z

[Term]
id: GO:1903796
name: negative regulation of inorganic anion transmembrane transport
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802]
synonym: "down regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie]
synonym: "down regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "down regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie]
synonym: "down-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie]
synonym: "down-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "down-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie]
synonym: "downregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie]
synonym: "downregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "downregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie]
synonym: "inhibition of inorganic anion membrane transport" NARROW [GOC:TermGenie]
synonym: "inhibition of inorganic anion transmembrane transport" NARROW [GOC:TermGenie]
synonym: "inhibition of transmembrane inorganic anion transport" NARROW [GOC:TermGenie]
synonym: "negative regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie]
synonym: "negative regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie]
is_a: GO:0034763 ! negative regulation of transmembrane transport
is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0098661 ! inorganic anion transmembrane transport
relationship: negatively_regulates GO:0098661 ! inorganic anion transmembrane transport
created_by: sl
creation_date: 2015-01-14T21:44:59Z

[Term]
id: GO:1903797
name: positive regulation of inorganic anion transmembrane transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802]
synonym: "activation of inorganic anion membrane transport" NARROW [GOC:TermGenie]
synonym: "activation of inorganic anion transmembrane transport" NARROW [GOC:TermGenie]
synonym: "activation of transmembrane inorganic anion transport" NARROW [GOC:TermGenie]
synonym: "positive regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie]
synonym: "positive regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie]
synonym: "up regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie]
synonym: "up regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "up regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie]
synonym: "up-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie]
synonym: "up-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "up-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie]
synonym: "upregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie]
synonym: "upregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie]
synonym: "upregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie]
is_a: GO:0034764 ! positive regulation of transmembrane transport
is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0098661 ! inorganic anion transmembrane transport
relationship: positively_regulates GO:0098661 ! inorganic anion transmembrane transport
created_by: sl
creation_date: 2015-01-14T21:45:08Z

[Term]
id: GO:1903825
name: organic acid transmembrane transport
namespace: biological_process
def: "The process in which an organic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie]
is_a: GO:0015849 ! organic acid transport
is_a: GO:0055085 ! transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:64709 ! organic acid
intersection_of: results_in_transport_across GO:0016020 ! membrane
created_by: vw
creation_date: 2015-01-20T10:20:58Z

[Term]
id: GO:1903828
name: negative regulation of protein localization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization." [GO_REF:0000058, GOC:TermGenie, GOC:vw]
synonym: "down regulation of cellular protein localisation" EXACT [GOC:TermGenie]
synonym: "down regulation of cellular protein localization" EXACT [GOC:TermGenie]
synonym: "down-regulation of cellular protein localisation" EXACT [GOC:TermGenie]
synonym: "down-regulation of cellular protein localization" EXACT [GOC:TermGenie]
synonym: "downregulation of cellular protein localisation" EXACT [GOC:TermGenie]
synonym: "downregulation of cellular protein localization" EXACT [GOC:TermGenie]
synonym: "inhibition of cellular protein localisation" NARROW [GOC:TermGenie]
synonym: "inhibition of cellular protein localization" NARROW [GOC:TermGenie]
synonym: "negative regulation of cellular protein localisation" EXACT [GOC:TermGenie]
synonym: "negative regulation of cellular protein localization" EXACT []
is_a: GO:0032880 ! regulation of protein localization
is_a: GO:0048523 ! negative regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008104 ! protein localization
relationship: negatively_regulates GO:0008104 ! protein localization
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI
created_by: jl
creation_date: 2015-01-20T14:32:24Z

[Term]
id: GO:1903829
name: positive regulation of protein localization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of a protein localization." [GO_REF:0000058, GOC:TermGenie, GOC:vw]
synonym: "positive regulation of cellular protein localisation" EXACT [GOC:TermGenie]
synonym: "positive regulation of cellular protein localization" EXACT []
synonym: "up regulation of cellular protein localisation" EXACT [GOC:TermGenie]
synonym: "up regulation of cellular protein localization" EXACT [GOC:TermGenie]
synonym: "up-regulation of cellular protein localisation" EXACT [GOC:TermGenie]
synonym: "up-regulation of cellular protein localization" EXACT [GOC:TermGenie]
synonym: "upregulation of cellular protein localisation" EXACT [GOC:TermGenie]
synonym: "upregulation of cellular protein localization" EXACT [GOC:TermGenie]
is_a: GO:0032880 ! regulation of protein localization
is_a: GO:0048522 ! positive regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008104 ! protein localization
relationship: positively_regulates GO:0008104 ! protein localization
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI
created_by: jl
creation_date: 2015-01-20T14:32:33Z

[Term]
id: GO:1903847
name: regulation of aorta morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326]
is_a: GO:1905651 ! regulation of artery morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035909 ! aorta morphogenesis
relationship: regulates GO:0035909 ! aorta morphogenesis
created_by: rph
creation_date: 2015-01-23T14:00:51Z

[Term]
id: GO:1903848
name: negative regulation of aorta morphogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326]
synonym: "down regulation of aorta morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of aorta morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of aorta morphogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of aorta morphogenesis" NARROW [GOC:TermGenie]
is_a: GO:1903847 ! regulation of aorta morphogenesis
is_a: GO:1905652 ! negative regulation of artery morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035909 ! aorta morphogenesis
relationship: negatively_regulates GO:0035909 ! aorta morphogenesis
created_by: rph
creation_date: 2015-01-23T14:01:01Z

[Term]
id: GO:1903849
name: positive regulation of aorta morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326]
synonym: "activation of aorta morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of aorta morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of aorta morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of aorta morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:1903847 ! regulation of aorta morphogenesis
is_a: GO:1905653 ! positive regulation of artery morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035909 ! aorta morphogenesis
relationship: positively_regulates GO:0035909 ! aorta morphogenesis
created_by: rph
creation_date: 2015-01-23T14:01:09Z

[Term]
id: GO:1903867
name: extraembryonic membrane development
namespace: biological_process
def: "The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0073040584]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0005631 ! extraembryonic membrane
relationship: results_in_development_of UBERON:0005631 ! extraembryonic membrane
created_by: cjm
creation_date: 2015-02-05T00:42:16Z

[Term]
id: GO:1903903
name: regulation of establishment of T cell polarity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248]
synonym: "regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie]
synonym: "regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "regulation of T cell polarization" EXACT [GOC:TermGenie]
synonym: "regulation of T lymphocyte polarization" EXACT [GOC:TermGenie]
synonym: "regulation of T-cell polarization" EXACT [GOC:TermGenie]
is_a: GO:2000114 ! regulation of establishment of cell polarity
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001768 ! establishment of T cell polarity
relationship: regulates GO:0001768 ! establishment of T cell polarity
created_by: als
creation_date: 2015-02-09T10:50:21Z

[Term]
id: GO:1903904
name: negative regulation of establishment of T cell polarity
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248]
synonym: "down regulation of establishment of T cell polarity" EXACT [GOC:TermGenie]
synonym: "down regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "down regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie]
synonym: "down regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "down regulation of T cell polarization" EXACT [GOC:TermGenie]
synonym: "down regulation of T lymphocyte polarization" EXACT [GOC:TermGenie]
synonym: "down regulation of T-cell polarization" EXACT [GOC:TermGenie]
synonym: "down-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie]
synonym: "down-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "down-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie]
synonym: "down-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "down-regulation of T cell polarization" EXACT [GOC:TermGenie]
synonym: "down-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie]
synonym: "down-regulation of T-cell polarization" EXACT [GOC:TermGenie]
synonym: "downregulation of establishment of T cell polarity" EXACT [GOC:TermGenie]
synonym: "downregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "downregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie]
synonym: "downregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "downregulation of T cell polarization" EXACT [GOC:TermGenie]
synonym: "downregulation of T lymphocyte polarization" EXACT [GOC:TermGenie]
synonym: "downregulation of T-cell polarization" EXACT [GOC:TermGenie]
synonym: "inhibition of establishment of T cell polarity" NARROW [GOC:TermGenie]
synonym: "inhibition of establishment of T lymphocyte polarity" NARROW [GOC:TermGenie]
synonym: "inhibition of establishment of T-cell polarity" NARROW [GOC:TermGenie]
synonym: "inhibition of establishment of T-lymphocyte polarity" NARROW [GOC:TermGenie]
synonym: "inhibition of T cell polarization" NARROW [GOC:TermGenie]
synonym: "inhibition of T lymphocyte polarization" NARROW [GOC:TermGenie]
synonym: "inhibition of T-cell polarization" NARROW [GOC:TermGenie]
synonym: "negative regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "negative regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie]
synonym: "negative regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "negative regulation of T cell polarization" EXACT [GOC:TermGenie]
synonym: "negative regulation of T lymphocyte polarization" EXACT [GOC:TermGenie]
synonym: "negative regulation of T-cell polarization" EXACT [GOC:TermGenie]
is_a: GO:0050868 ! negative regulation of T cell activation
is_a: GO:1903903 ! regulation of establishment of T cell polarity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001768 ! establishment of T cell polarity
relationship: negatively_regulates GO:0001768 ! establishment of T cell polarity
created_by: als
creation_date: 2015-02-09T10:50:30Z

[Term]
id: GO:1903905
name: positive regulation of establishment of T cell polarity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248]
synonym: "activation of establishment of T cell polarity" NARROW [GOC:TermGenie]
synonym: "activation of establishment of T lymphocyte polarity" NARROW [GOC:TermGenie]
synonym: "activation of establishment of T-cell polarity" NARROW [GOC:TermGenie]
synonym: "activation of establishment of T-lymphocyte polarity" NARROW [GOC:TermGenie]
synonym: "activation of T cell polarization" NARROW [GOC:TermGenie]
synonym: "activation of T lymphocyte polarization" NARROW [GOC:TermGenie]
synonym: "activation of T-cell polarization" NARROW [GOC:TermGenie]
synonym: "positive regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "positive regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie]
synonym: "positive regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "positive regulation of T cell polarization" EXACT [GOC:TermGenie]
synonym: "positive regulation of T lymphocyte polarization" EXACT [GOC:TermGenie]
synonym: "positive regulation of T-cell polarization" EXACT [GOC:TermGenie]
synonym: "up regulation of establishment of T cell polarity" EXACT [GOC:TermGenie]
synonym: "up regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "up regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie]
synonym: "up regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "up regulation of T cell polarization" EXACT [GOC:TermGenie]
synonym: "up regulation of T lymphocyte polarization" EXACT [GOC:TermGenie]
synonym: "up regulation of T-cell polarization" EXACT [GOC:TermGenie]
synonym: "up-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie]
synonym: "up-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "up-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie]
synonym: "up-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "up-regulation of T cell polarization" EXACT [GOC:TermGenie]
synonym: "up-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie]
synonym: "up-regulation of T-cell polarization" EXACT [GOC:TermGenie]
synonym: "upregulation of establishment of T cell polarity" EXACT [GOC:TermGenie]
synonym: "upregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "upregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie]
synonym: "upregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie]
synonym: "upregulation of T cell polarization" EXACT [GOC:TermGenie]
synonym: "upregulation of T lymphocyte polarization" EXACT [GOC:TermGenie]
synonym: "upregulation of T-cell polarization" EXACT [GOC:TermGenie]
is_a: GO:0050870 ! positive regulation of T cell activation
is_a: GO:1903903 ! regulation of establishment of T cell polarity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001768 ! establishment of T cell polarity
relationship: positively_regulates GO:0001768 ! establishment of T cell polarity
created_by: als
creation_date: 2015-02-09T10:50:40Z

[Term]
id: GO:1903941
name: negative regulation of respiratory gaseous exchange
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705]
synonym: "down regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie]
synonym: "down-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie]
synonym: "downregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie]
synonym: "inhibition of respiratory gaseous exchange" NARROW [GOC:TermGenie]
is_a: GO:0043576 ! regulation of respiratory gaseous exchange
is_a: GO:0051241 ! negative regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system
relationship: negatively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system
created_by: sl
creation_date: 2015-02-17T20:26:24Z

[Term]
id: GO:1903942
name: positive regulation of respiratory gaseous exchange
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705]
synonym: "activation of respiratory gaseous exchange" NARROW [GOC:TermGenie]
synonym: "up regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie]
synonym: "up-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie]
synonym: "upregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie]
is_a: GO:0043576 ! regulation of respiratory gaseous exchange
is_a: GO:0051240 ! positive regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system
relationship: positively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system
created_by: sl
creation_date: 2015-02-17T20:26:35Z

[Term]
id: GO:1903943
name: regulation of hepatocyte apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852]
synonym: "regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie]
is_a: GO:1904035 ! regulation of epithelial cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097284 ! hepatocyte apoptotic process
relationship: regulates GO:0097284 ! hepatocyte apoptotic process
created_by: sl
creation_date: 2015-02-19T12:54:40Z

[Term]
id: GO:1903944
name: negative regulation of hepatocyte apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852]
synonym: "down regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of hepatocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "inhibition of hepatocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of hepatocyte apoptotic process" NARROW [GOC:TermGenie]
synonym: "negative regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie]
is_a: GO:1903943 ! regulation of hepatocyte apoptotic process
is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097284 ! hepatocyte apoptotic process
relationship: negatively_regulates GO:0097284 ! hepatocyte apoptotic process
created_by: sl
creation_date: 2015-02-19T12:54:50Z

[Term]
id: GO:1903945
name: positive regulation of hepatocyte apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852]
synonym: "activation of hepatocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of hepatocyte apoptotic process" NARROW [GOC:TermGenie]
synonym: "positive regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of hepatocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:1903943 ! regulation of hepatocyte apoptotic process
is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097284 ! hepatocyte apoptotic process
relationship: positively_regulates GO:0097284 ! hepatocyte apoptotic process
created_by: sl
creation_date: 2015-02-19T12:54:59Z

[Term]
id: GO:1903950
name: negative regulation of AV node cell action potential
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747]
synonym: "down regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "down regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "down regulation of AV node cell action potential" EXACT [GOC:TermGenie]
synonym: "down-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "down-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "down-regulation of AV node cell action potential" EXACT [GOC:TermGenie]
synonym: "downregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "downregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "downregulation of AV node cell action potential" EXACT [GOC:TermGenie]
synonym: "inhibition of atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie]
synonym: "inhibition of AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie]
synonym: "inhibition of AV node cell action potential" NARROW [GOC:TermGenie]
synonym: "negative regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "negative regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
is_a: GO:0045759 ! negative regulation of action potential
is_a: GO:0098904 ! regulation of AV node cell action potential
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0086016 ! AV node cell action potential
relationship: negatively_regulates GO:0086016 ! AV node cell action potential
created_by: nc
creation_date: 2015-02-20T14:59:41Z

[Term]
id: GO:1903951
name: positive regulation of AV node cell action potential
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747]
synonym: "activation of atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie]
synonym: "activation of AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie]
synonym: "activation of AV node cell action potential" NARROW [GOC:TermGenie]
synonym: "positive regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "positive regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "up regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "up regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "up regulation of AV node cell action potential" EXACT [GOC:TermGenie]
synonym: "up-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "up-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "up-regulation of AV node cell action potential" EXACT [GOC:TermGenie]
synonym: "upregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "upregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie]
synonym: "upregulation of AV node cell action potential" EXACT [GOC:TermGenie]
is_a: GO:0045760 ! positive regulation of action potential
is_a: GO:0098904 ! regulation of AV node cell action potential
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0086016 ! AV node cell action potential
relationship: positively_regulates GO:0086016 ! AV node cell action potential
created_by: nc
creation_date: 2015-02-20T14:59:50Z

[Term]
id: GO:1903975
name: regulation of glial cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238]
synonym: "regulation of glia cell migration" EXACT [GOC:TermGenie]
is_a: GO:0030334 ! regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008347 ! glial cell migration
relationship: regulates GO:0008347 ! glial cell migration
created_by: nc
creation_date: 2015-03-02T15:13:31Z

[Term]
id: GO:1903976
name: negative regulation of glial cell migration
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238]
synonym: "down regulation of glia cell migration" EXACT [GOC:TermGenie]
synonym: "down regulation of glial cell migration" EXACT [GOC:TermGenie]
synonym: "down-regulation of glia cell migration" EXACT [GOC:TermGenie]
synonym: "down-regulation of glial cell migration" EXACT [GOC:TermGenie]
synonym: "downregulation of glia cell migration" EXACT [GOC:TermGenie]
synonym: "downregulation of glial cell migration" EXACT [GOC:TermGenie]
synonym: "inhibition of glia cell migration" NARROW [GOC:TermGenie]
synonym: "inhibition of glial cell migration" NARROW [GOC:TermGenie]
synonym: "negative regulation of glia cell migration" EXACT [GOC:TermGenie]
is_a: GO:0030336 ! negative regulation of cell migration
is_a: GO:1903975 ! regulation of glial cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008347 ! glial cell migration
relationship: negatively_regulates GO:0008347 ! glial cell migration
created_by: nc
creation_date: 2015-03-02T15:13:38Z

[Term]
id: GO:1903977
name: positive regulation of glial cell migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238]
synonym: "activation of glia cell migration" NARROW [GOC:TermGenie]
synonym: "activation of glial cell migration" NARROW [GOC:TermGenie]
synonym: "positive regulation of glia cell migration" EXACT [GOC:TermGenie]
synonym: "up regulation of glia cell migration" EXACT [GOC:TermGenie]
synonym: "up regulation of glial cell migration" EXACT [GOC:TermGenie]
synonym: "up-regulation of glia cell migration" EXACT [GOC:TermGenie]
synonym: "up-regulation of glial cell migration" EXACT [GOC:TermGenie]
synonym: "upregulation of glia cell migration" EXACT [GOC:TermGenie]
synonym: "upregulation of glial cell migration" EXACT [GOC:TermGenie]
is_a: GO:0030335 ! positive regulation of cell migration
is_a: GO:1903975 ! regulation of glial cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008347 ! glial cell migration
relationship: positively_regulates GO:0008347 ! glial cell migration
created_by: nc
creation_date: 2015-03-02T15:13:43Z

[Term]
id: GO:1904014
name: response to serotonin
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1505525]
is_a: GO:1901698 ! response to nitrogen compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+)
relationship: has_primary_input CHEBI:350546 ! serotonin(1+)
created_by: sl
creation_date: 2015-03-06T19:33:54Z

[Term]
id: GO:1904018
name: positive regulation of vasculature development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vasculature development." [GO_REF:0000058, GOC:TermGenie, PMID:21472453]
synonym: "activation of vascular system development" RELATED [GOC:TermGenie]
synonym: "activation of vasculature development" NARROW [GOC:TermGenie]
synonym: "positive regulation of vascular system development" RELATED [GOC:TermGenie]
synonym: "up regulation of vascular system development" RELATED [GOC:TermGenie]
synonym: "up regulation of vasculature development" EXACT [GOC:TermGenie]
synonym: "up-regulation of vascular system development" RELATED [GOC:TermGenie]
synonym: "up-regulation of vasculature development" EXACT [GOC:TermGenie]
synonym: "upregulation of vascular system development" RELATED [GOC:TermGenie]
synonym: "upregulation of vasculature development" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1901342 ! regulation of vasculature development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001944 ! vasculature development
relationship: positively_regulates GO:0001944 ! vasculature development
created_by: sl
creation_date: 2015-03-06T22:17:04Z

[Term]
id: GO:1904019
name: epithelial cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in an epithelial cell." [GO_REF:0000085, GOC:TermGenie, PMID:19137015]
synonym: "epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "epitheliocyte apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000066 ! epithelial cell
relationship: occurs_in CL:0000066 ! epithelial cell
property_value: RO:0002161 NCBITaxon:33090
property_value: RO:0002161 NCBITaxon_Union:0000023
created_by: sl
creation_date: 2015-03-06T22:27:17Z

[Term]
id: GO:1904026
name: regulation of collagen fibril organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920]
synonym: "regulation of collagen fibril organisation" EXACT [GOC:TermGenie]
synonym: "regulation of collagen fibrillogenesis" RELATED []
synonym: "regulation of fibrillar collagen organization" EXACT [GOC:TermGenie]
is_a: GO:1902903 ! regulation of supramolecular fiber organization
is_a: GO:1903053 ! regulation of extracellular matrix organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030199 ! collagen fibril organization
relationship: regulates GO:0030199 ! collagen fibril organization
created_by: ae
creation_date: 2015-03-12T12:36:52Z

[Term]
id: GO:1904027
name: negative regulation of collagen fibril organization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920]
synonym: "down regulation of collagen fibril organisation" EXACT [GOC:TermGenie]
synonym: "down regulation of collagen fibril organization" EXACT [GOC:TermGenie]
synonym: "down regulation of fibrillar collagen organization" EXACT [GOC:TermGenie]
synonym: "down-regulation of collagen fibril organisation" EXACT [GOC:TermGenie]
synonym: "down-regulation of collagen fibril organization" EXACT [GOC:TermGenie]
synonym: "down-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie]
synonym: "downregulation of collagen fibril organisation" EXACT [GOC:TermGenie]
synonym: "downregulation of collagen fibril organization" EXACT [GOC:TermGenie]
synonym: "downregulation of fibrillar collagen organization" EXACT [GOC:TermGenie]
synonym: "inhibition of collagen fibril organisation" NARROW [GOC:TermGenie]
synonym: "inhibition of collagen fibril organization" NARROW [GOC:TermGenie]
synonym: "inhibition of fibrillar collagen organization" NARROW [GOC:TermGenie]
synonym: "negative regulation of collagen fibril organisation" EXACT [GOC:TermGenie]
synonym: "negative regulation of fibrillar collagen organization" EXACT [GOC:TermGenie]
is_a: GO:1902904 ! negative regulation of supramolecular fiber organization
is_a: GO:1903054 ! negative regulation of extracellular matrix organization
is_a: GO:1904026 ! regulation of collagen fibril organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030199 ! collagen fibril organization
relationship: negatively_regulates GO:0030199 ! collagen fibril organization
created_by: ae
creation_date: 2015-03-12T12:36:59Z

[Term]
id: GO:1904028
name: positive regulation of collagen fibril organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920]
synonym: "activation of collagen fibril organisation" NARROW [GOC:TermGenie]
synonym: "activation of collagen fibril organization" NARROW [GOC:TermGenie]
synonym: "activation of fibrillar collagen organization" NARROW [GOC:TermGenie]
synonym: "positive regulation of collagen fibril organisation" EXACT [GOC:TermGenie]
synonym: "positive regulation of fibrillar collagen organization" EXACT [GOC:TermGenie]
synonym: "up regulation of collagen fibril organisation" EXACT [GOC:TermGenie]
synonym: "up regulation of collagen fibril organization" EXACT [GOC:TermGenie]
synonym: "up regulation of fibrillar collagen organization" EXACT [GOC:TermGenie]
synonym: "up-regulation of collagen fibril organisation" EXACT [GOC:TermGenie]
synonym: "up-regulation of collagen fibril organization" EXACT [GOC:TermGenie]
synonym: "up-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie]
synonym: "upregulation of collagen fibril organisation" EXACT [GOC:TermGenie]
synonym: "upregulation of collagen fibril organization" EXACT [GOC:TermGenie]
synonym: "upregulation of fibrillar collagen organization" EXACT [GOC:TermGenie]
is_a: GO:1902905 ! positive regulation of supramolecular fiber organization
is_a: GO:1903055 ! positive regulation of extracellular matrix organization
is_a: GO:1904026 ! regulation of collagen fibril organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030199 ! collagen fibril organization
relationship: positively_regulates GO:0030199 ! collagen fibril organization
created_by: ae
creation_date: 2015-03-12T12:37:06Z

[Term]
id: GO:1904035
name: regulation of epithelial cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015]
synonym: "regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1904019 ! epithelial cell apoptotic process
relationship: regulates GO:1904019 ! epithelial cell apoptotic process
created_by: sl
creation_date: 2015-03-13T22:05:41Z

[Term]
id: GO:1904036
name: negative regulation of epithelial cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015]
synonym: "down regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "inhibition of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of epithelial cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "inhibition of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of epitheliocyte apoptotic process" NARROW [GOC:TermGenie]
synonym: "negative regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0043066 ! negative regulation of apoptotic process
is_a: GO:1904035 ! regulation of epithelial cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1904019 ! epithelial cell apoptotic process
relationship: negatively_regulates GO:1904019 ! epithelial cell apoptotic process
created_by: sl
creation_date: 2015-03-13T22:05:47Z

[Term]
id: GO:1904037
name: positive regulation of epithelial cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015]
synonym: "activation of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of epithelial cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "activation of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of epitheliocyte apoptotic process" NARROW [GOC:TermGenie]
synonym: "positive regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of epithelial cell apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0043065 ! positive regulation of apoptotic process
is_a: GO:1904035 ! regulation of epithelial cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1904019 ! epithelial cell apoptotic process
relationship: positively_regulates GO:1904019 ! epithelial cell apoptotic process
created_by: sl
creation_date: 2015-03-13T22:05:53Z

[Term]
id: GO:1904054
name: regulation of cholangiocyte proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010]
synonym: "regulation of hepatoblast proliferation" EXACT [GOC:TermGenie]
is_a: GO:0050678 ! regulation of epithelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1990705 ! cholangiocyte proliferation
relationship: regulates GO:1990705 ! cholangiocyte proliferation
created_by: sl
creation_date: 2015-03-18T17:56:14Z

[Term]
id: GO:1904055
name: negative regulation of cholangiocyte proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010]
synonym: "down regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie]
synonym: "down regulation of hepatoblast proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of hepatoblast proliferation" EXACT [GOC:TermGenie]
synonym: "inhibition of cholangiocyte proliferation" NARROW [GOC:TermGenie]
synonym: "inhibition of hepatoblast proliferation" NARROW [GOC:TermGenie]
synonym: "negative regulation of hepatoblast proliferation" EXACT [GOC:TermGenie]
is_a: GO:0050680 ! negative regulation of epithelial cell proliferation
is_a: GO:1904054 ! regulation of cholangiocyte proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1990705 ! cholangiocyte proliferation
relationship: negatively_regulates GO:1990705 ! cholangiocyte proliferation
created_by: sl
creation_date: 2015-03-18T17:56:20Z

[Term]
id: GO:1904056
name: positive regulation of cholangiocyte proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010]
synonym: "activation of cholangiocyte proliferation" NARROW [GOC:TermGenie]
synonym: "activation of hepatoblast proliferation" NARROW [GOC:TermGenie]
synonym: "positive regulation of hepatoblast proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of hepatoblast proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of hepatoblast proliferation" EXACT [GOC:TermGenie]
is_a: GO:0050679 ! positive regulation of epithelial cell proliferation
is_a: GO:1904054 ! regulation of cholangiocyte proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1990705 ! cholangiocyte proliferation
relationship: positively_regulates GO:1990705 ! cholangiocyte proliferation
created_by: sl
creation_date: 2015-03-18T17:56:26Z

[Term]
id: GO:1904057
name: negative regulation of sensory perception of pain
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094]
synonym: "down regulation of nociception" EXACT [GOC:TermGenie]
synonym: "down regulation of perception of physiological pain" NARROW [GOC:TermGenie]
synonym: "down regulation of sensory perception of pain" EXACT [GOC:TermGenie]
synonym: "down-regulation of nociception" EXACT [GOC:TermGenie]
synonym: "down-regulation of perception of physiological pain" NARROW [GOC:TermGenie]
synonym: "down-regulation of sensory perception of pain" EXACT [GOC:TermGenie]
synonym: "downregulation of nociception" EXACT [GOC:TermGenie]
synonym: "downregulation of perception of physiological pain" NARROW [GOC:TermGenie]
synonym: "downregulation of sensory perception of pain" EXACT [GOC:TermGenie]
synonym: "inhibition of nociception" NARROW [GOC:TermGenie]
synonym: "inhibition of perception of physiological pain" NARROW [GOC:TermGenie]
synonym: "inhibition of sensory perception of pain" NARROW [GOC:TermGenie]
synonym: "negative regulation of nociception" EXACT [GOC:TermGenie]
synonym: "negative regulation of perception of physiological pain" NARROW [GOC:TermGenie]
is_a: GO:0031645 ! negative regulation of nervous system process
is_a: GO:0051930 ! regulation of sensory perception of pain
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0019233 ! sensory perception of pain
relationship: negatively_regulates GO:0019233 ! sensory perception of pain
created_by: sl
creation_date: 2015-03-18T20:33:57Z

[Term]
id: GO:1904058
name: positive regulation of sensory perception of pain
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094]
synonym: "activation of nociception" NARROW [GOC:TermGenie]
synonym: "activation of perception of physiological pain" NARROW [GOC:TermGenie]
synonym: "activation of sensory perception of pain" NARROW [GOC:TermGenie]
synonym: "positive regulation of nociception" EXACT [GOC:TermGenie]
synonym: "positive regulation of perception of physiological pain" NARROW [GOC:TermGenie]
synonym: "up regulation of nociception" EXACT [GOC:TermGenie]
synonym: "up regulation of perception of physiological pain" NARROW [GOC:TermGenie]
synonym: "up regulation of sensory perception of pain" EXACT [GOC:TermGenie]
synonym: "up-regulation of nociception" EXACT [GOC:TermGenie]
synonym: "up-regulation of perception of physiological pain" NARROW [GOC:TermGenie]
synonym: "up-regulation of sensory perception of pain" EXACT [GOC:TermGenie]
synonym: "upregulation of nociception" EXACT [GOC:TermGenie]
synonym: "upregulation of perception of physiological pain" NARROW [GOC:TermGenie]
synonym: "upregulation of sensory perception of pain" EXACT [GOC:TermGenie]
is_a: GO:0031646 ! positive regulation of nervous system process
is_a: GO:0051930 ! regulation of sensory perception of pain
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0019233 ! sensory perception of pain
relationship: positively_regulates GO:0019233 ! sensory perception of pain
created_by: sl
creation_date: 2015-03-18T20:34:03Z

[Term]
id: GO:1904062
name: regulation of monoatomic cation transmembrane transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482]
synonym: "regulation of cation transmembrane transport" BROAD []
is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0098655 ! monoatomic cation transmembrane transport
relationship: regulates GO:0098655 ! monoatomic cation transmembrane transport
created_by: sl
creation_date: 2015-03-18T21:11:43Z

[Term]
id: GO:1904063
name: negative regulation of cation transmembrane transport
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482]
synonym: "down regulation of cation transmembrane transport" EXACT [GOC:TermGenie]
synonym: "down-regulation of cation transmembrane transport" EXACT [GOC:TermGenie]
synonym: "downregulation of cation transmembrane transport" EXACT [GOC:TermGenie]
synonym: "inhibition of cation transmembrane transport" NARROW [GOC:TermGenie]
is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport
is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0098655 ! monoatomic cation transmembrane transport
relationship: negatively_regulates GO:0098655 ! monoatomic cation transmembrane transport
created_by: sl
creation_date: 2015-03-18T21:11:50Z

[Term]
id: GO:1904064
name: positive regulation of cation transmembrane transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482]
synonym: "activation of cation transmembrane transport" NARROW [GOC:TermGenie]
synonym: "up regulation of cation transmembrane transport" EXACT [GOC:TermGenie]
synonym: "up-regulation of cation transmembrane transport" EXACT [GOC:TermGenie]
synonym: "upregulation of cation transmembrane transport" EXACT [GOC:TermGenie]
is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport
is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0098655 ! monoatomic cation transmembrane transport
relationship: positively_regulates GO:0098655 ! monoatomic cation transmembrane transport
created_by: sl
creation_date: 2015-03-18T21:11:55Z

[Term]
id: GO:1904073
name: regulation of trophectodermal cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636]
synonym: "regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0042127 ! regulation of cell population proliferation
is_a: GO:0048638 ! regulation of developmental growth
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001834 ! trophectodermal cell proliferation
relationship: regulates GO:0001834 ! trophectodermal cell proliferation
created_by: tb
creation_date: 2015-03-20T16:55:56Z

[Term]
id: GO:1904074
name: negative regulation of trophectodermal cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636]
synonym: "down regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie]
synonym: "down regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie]
synonym: "inhibition of trophectoderm cell proliferation" NARROW [GOC:TermGenie]
synonym: "inhibition of trophectodermal cell proliferation" NARROW [GOC:TermGenie]
synonym: "negative regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:1904073 ! regulation of trophectodermal cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001834 ! trophectodermal cell proliferation
relationship: negatively_regulates GO:0001834 ! trophectodermal cell proliferation
created_by: tb
creation_date: 2015-03-20T16:56:02Z

[Term]
id: GO:1904075
name: positive regulation of trophectodermal cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636]
synonym: "activation of trophectoderm cell proliferation" NARROW [GOC:TermGenie]
synonym: "activation of trophectodermal cell proliferation" NARROW [GOC:TermGenie]
synonym: "positive regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:1904073 ! regulation of trophectodermal cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001834 ! trophectodermal cell proliferation
relationship: positively_regulates GO:0001834 ! trophectodermal cell proliferation
created_by: tb
creation_date: 2015-03-20T16:56:08Z

[Term]
id: GO:1904106
name: protein localization to microvillus
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a microvillus." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:25335890]
synonym: "protein localisation in microvillus" EXACT [GOC:TermGenie]
synonym: "protein localisation to microvillus" EXACT [GOC:TermGenie]
synonym: "protein localization in microvillus" EXACT [GOC:TermGenie]
is_a: GO:0008104 ! protein localization
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005902 ! microvillus
relationship: has_target_end_location GO:0005902 ! microvillus
created_by: kmv
creation_date: 2015-04-01T18:14:41Z

[Term]
id: GO:1904145
name: negative regulation of meiotic cell cycle process involved in oocyte maturation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394]
synonym: "down regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie]
synonym: "down-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie]
synonym: "downregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie]
synonym: "inhibition of meiotic cell cycle process involved in oocyte maturation" NARROW [GOC:TermGenie]
is_a: GO:0010948 ! negative regulation of cell cycle process
is_a: GO:0051447 ! negative regulation of meiotic cell cycle
is_a: GO:1900194 ! negative regulation of oocyte maturation
is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation
relationship: negatively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation
created_by: tb
creation_date: 2015-04-14T15:59:22Z

[Term]
id: GO:1904146
name: positive regulation of meiotic cell cycle process involved in oocyte maturation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394]
synonym: "activation of meiotic cell cycle process involved in oocyte maturation" NARROW [GOC:TermGenie]
synonym: "up regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie]
synonym: "up-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie]
synonym: "upregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie]
is_a: GO:0051446 ! positive regulation of meiotic cell cycle
is_a: GO:0090068 ! positive regulation of cell cycle process
is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation
relationship: positively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation
created_by: tb
creation_date: 2015-04-14T15:59:28Z

[Term]
id: GO:1904170
name: regulation of bleb assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887]
synonym: "regulation of cell blebbing" EXACT [GOC:TermGenie]
is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032060 ! bleb assembly
relationship: regulates GO:0032060 ! bleb assembly
created_by: als
creation_date: 2015-04-23T09:32:19Z

[Term]
id: GO:1904171
name: negative regulation of bleb assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887]
synonym: "down regulation of bleb assembly" EXACT [GOC:TermGenie]
synonym: "down regulation of cell blebbing" EXACT [GOC:TermGenie]
synonym: "down-regulation of bleb assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of cell blebbing" EXACT [GOC:TermGenie]
synonym: "downregulation of bleb assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of cell blebbing" EXACT [GOC:TermGenie]
synonym: "inhibition of bleb assembly" NARROW [GOC:TermGenie]
synonym: "inhibition of cell blebbing" NARROW [GOC:TermGenie]
synonym: "negative regulation of cell blebbing" EXACT [GOC:TermGenie]
is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly
is_a: GO:1904170 ! regulation of bleb assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0032060 ! bleb assembly
relationship: negatively_regulates GO:0032060 ! bleb assembly
created_by: als
creation_date: 2015-04-23T09:32:25Z

[Term]
id: GO:1904172
name: positive regulation of bleb assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887]
synonym: "activation of bleb assembly" NARROW [GOC:TermGenie]
synonym: "activation of cell blebbing" NARROW [GOC:TermGenie]
synonym: "positive regulation of cell blebbing" EXACT [GOC:TermGenie]
synonym: "up regulation of bleb assembly" EXACT [GOC:TermGenie]
synonym: "up regulation of cell blebbing" EXACT [GOC:TermGenie]
synonym: "up-regulation of bleb assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of cell blebbing" EXACT [GOC:TermGenie]
synonym: "upregulation of bleb assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of cell blebbing" EXACT [GOC:TermGenie]
is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly
is_a: GO:1904170 ! regulation of bleb assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0032060 ! bleb assembly
relationship: positively_regulates GO:0032060 ! bleb assembly
created_by: als
creation_date: 2015-04-23T09:32:31Z

[Term]
id: GO:1904177
name: regulation of adipose tissue development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848]
synonym: "regulation of adipogenesis" RELATED [GOC:TermGenie]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060612 ! adipose tissue development
relationship: regulates GO:0060612 ! adipose tissue development
created_by: sl
creation_date: 2015-04-29T20:01:01Z

[Term]
id: GO:1904178
name: negative regulation of adipose tissue development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848]
synonym: "down regulation of adipogenesis" RELATED [GOC:TermGenie]
synonym: "down regulation of adipose tissue development" EXACT [GOC:TermGenie]
synonym: "down-regulation of adipogenesis" RELATED [GOC:TermGenie]
synonym: "down-regulation of adipose tissue development" EXACT [GOC:TermGenie]
synonym: "downregulation of adipogenesis" RELATED [GOC:TermGenie]
synonym: "downregulation of adipose tissue development" EXACT [GOC:TermGenie]
synonym: "inhibition of adipogenesis" RELATED [GOC:TermGenie]
synonym: "inhibition of adipose tissue development" NARROW [GOC:TermGenie]
synonym: "negative regulation of adipogenesis" RELATED [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1904177 ! regulation of adipose tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060612 ! adipose tissue development
relationship: negatively_regulates GO:0060612 ! adipose tissue development
created_by: sl
creation_date: 2015-04-29T20:01:07Z

[Term]
id: GO:1904179
name: positive regulation of adipose tissue development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848]
synonym: "activation of adipogenesis" RELATED [GOC:TermGenie]
synonym: "activation of adipose tissue development" NARROW [GOC:TermGenie]
synonym: "positive regulation of adipogenesis" RELATED [GOC:TermGenie]
synonym: "up regulation of adipogenesis" RELATED [GOC:TermGenie]
synonym: "up regulation of adipose tissue development" EXACT [GOC:TermGenie]
synonym: "up-regulation of adipogenesis" RELATED [GOC:TermGenie]
synonym: "up-regulation of adipose tissue development" EXACT [GOC:TermGenie]
synonym: "upregulation of adipogenesis" RELATED [GOC:TermGenie]
synonym: "upregulation of adipose tissue development" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1904177 ! regulation of adipose tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060612 ! adipose tissue development
relationship: positively_regulates GO:0060612 ! adipose tissue development
created_by: sl
creation_date: 2015-04-29T20:01:13Z

[Term]
id: GO:1904192
name: regulation of cholangiocyte apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161]
synonym: "regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:1904035 ! regulation of epithelial cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1902488 ! cholangiocyte apoptotic process
relationship: regulates GO:1902488 ! cholangiocyte apoptotic process
created_by: sl
creation_date: 2015-05-06T15:25:48Z

[Term]
id: GO:1904193
name: negative regulation of cholangiocyte apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161]
synonym: "down regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "down regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie]
synonym: "inhibition of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of cholangiocyte apoptotic process" NARROW [GOC:TermGenie]
synonym: "inhibition of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of epithelial cell of bile duct apoptotic process" NARROW [GOC:TermGenie]
synonym: "negative regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process
is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1902488 ! cholangiocyte apoptotic process
relationship: negatively_regulates GO:1902488 ! cholangiocyte apoptotic process
created_by: sl
creation_date: 2015-05-06T15:25:55Z

[Term]
id: GO:1904194
name: positive regulation of cholangiocyte apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161]
synonym: "activation of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of cholangiocyte apoptotic process" NARROW [GOC:TermGenie]
synonym: "activation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of epithelial cell of bile duct apoptotic process" NARROW [GOC:TermGenie]
synonym: "positive regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process
is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1902488 ! cholangiocyte apoptotic process
relationship: positively_regulates GO:1902488 ! cholangiocyte apoptotic process
created_by: sl
creation_date: 2015-05-06T15:26:00Z

[Term]
id: GO:1904204
name: regulation of skeletal muscle hypertrophy
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307]
is_a: GO:0014733 ! regulation of skeletal muscle adaptation
is_a: GO:0014743 ! regulation of muscle hypertrophy
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014734 ! skeletal muscle hypertrophy
relationship: regulates GO:0014734 ! skeletal muscle hypertrophy
created_by: sl
creation_date: 2015-05-08T17:38:13Z

[Term]
id: GO:1904205
name: negative regulation of skeletal muscle hypertrophy
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307]
synonym: "down regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie]
synonym: "down-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie]
synonym: "downregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie]
synonym: "inhibition of skeletal muscle hypertrophy" NARROW [GOC:TermGenie]
is_a: GO:0014741 ! negative regulation of muscle hypertrophy
is_a: GO:0014745 ! negative regulation of muscle adaptation
is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014734 ! skeletal muscle hypertrophy
relationship: negatively_regulates GO:0014734 ! skeletal muscle hypertrophy
created_by: sl
creation_date: 2015-05-08T17:38:19Z

[Term]
id: GO:1904206
name: positive regulation of skeletal muscle hypertrophy
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307]
synonym: "activation of skeletal muscle hypertrophy" NARROW [GOC:TermGenie]
synonym: "up regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie]
synonym: "up-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie]
synonym: "upregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie]
is_a: GO:0014742 ! positive regulation of muscle hypertrophy
is_a: GO:0014744 ! positive regulation of muscle adaptation
is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014734 ! skeletal muscle hypertrophy
relationship: positively_regulates GO:0014734 ! skeletal muscle hypertrophy
created_by: sl
creation_date: 2015-05-08T17:38:25Z

[Term]
id: GO:1904251
name: regulation of bile acid metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie]
synonym: "regulation of bile acid metabolism" EXACT [GOC:TermGenie]
is_a: GO:0019218 ! regulation of steroid metabolic process
is_a: GO:0031323 ! regulation of cellular metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008206 ! bile acid metabolic process
relationship: regulates GO:0008206 ! bile acid metabolic process
created_by: bf
creation_date: 2015-05-20T11:04:28Z

[Term]
id: GO:1904252
name: negative regulation of bile acid metabolic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie]
synonym: "down regulation of bile acid metabolic process" EXACT [GOC:TermGenie]
synonym: "down regulation of bile acid metabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of bile acid metabolic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of bile acid metabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of bile acid metabolic process" EXACT [GOC:TermGenie]
synonym: "downregulation of bile acid metabolism" EXACT [GOC:TermGenie]
synonym: "inhibition of bile acid metabolic process" NARROW [GOC:TermGenie]
synonym: "inhibition of bile acid metabolism" NARROW [GOC:TermGenie]
synonym: "negative regulation of bile acid metabolism" EXACT [GOC:TermGenie]
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0045939 ! negative regulation of steroid metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
is_a: GO:1904251 ! regulation of bile acid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008206 ! bile acid metabolic process
relationship: negatively_regulates GO:0008206 ! bile acid metabolic process
created_by: bf
creation_date: 2015-05-20T11:04:35Z

[Term]
id: GO:1904253
name: positive regulation of bile acid metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie]
synonym: "activation of bile acid metabolic process" NARROW [GOC:TermGenie]
synonym: "activation of bile acid metabolism" NARROW [GOC:TermGenie]
synonym: "positive regulation of bile acid metabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of bile acid metabolic process" EXACT [GOC:TermGenie]
synonym: "up regulation of bile acid metabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of bile acid metabolic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of bile acid metabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of bile acid metabolic process" EXACT [GOC:TermGenie]
synonym: "upregulation of bile acid metabolism" EXACT [GOC:TermGenie]
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0045940 ! positive regulation of steroid metabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
is_a: GO:1904251 ! regulation of bile acid metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008206 ! bile acid metabolic process
relationship: positively_regulates GO:0008206 ! bile acid metabolic process
created_by: bf
creation_date: 2015-05-20T11:04:40Z

[Term]
id: GO:1904269
name: cell leading edge cell cortex
namespace: cellular_component
def: "The cell cortex of the leading edge of a cell." [GO_REF:0000064, GOC:kmv, GOC:TermGenie, PMID:25843030]
synonym: "cell cortex of cell leading edge" EXACT [GOC:TermGenie]
synonym: "cell cortex of front of cell" EXACT [GOC:TermGenie]
synonym: "cell cortex of leading edge of cell" EXACT [GOC:TermGenie]
synonym: "cell periphery of cell leading edge" RELATED [GOC:TermGenie]
synonym: "cell periphery of front of cell" RELATED [GOC:TermGenie]
synonym: "cell periphery of leading edge of cell" RELATED [GOC:TermGenie]
synonym: "peripheral cytoplasm of cell leading edge" RELATED [GOC:TermGenie]
synonym: "peripheral cytoplasm of front of cell" RELATED [GOC:TermGenie]
synonym: "peripheral cytoplasm of leading edge of cell" RELATED [GOC:TermGenie]
is_a: GO:0099738 ! cell cortex region
intersection_of: GO:0099738 ! cell cortex region
intersection_of: part_of GO:0031252 ! cell leading edge
relationship: part_of GO:0031252 ! cell leading edge
created_by: kmv
creation_date: 2015-05-28T19:16:03Z

[Term]
id: GO:1904304
name: regulation of gastro-intestinal system smooth muscle contraction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044]
is_a: GO:0006940 ! regulation of smooth muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction
relationship: regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction
created_by: sl
creation_date: 2015-06-09T23:18:42Z

[Term]
id: GO:1904305
name: negative regulation of gastro-intestinal system smooth muscle contraction
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044]
synonym: "down regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "down-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "downregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "inhibition of gastro-intestinal system smooth muscle contraction" NARROW [GOC:TermGenie]
is_a: GO:0045986 ! negative regulation of smooth muscle contraction
is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction
relationship: negatively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction
created_by: sl
creation_date: 2015-06-09T23:18:48Z

[Term]
id: GO:1904306
name: positive regulation of gastro-intestinal system smooth muscle contraction
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044]
synonym: "activation of gastro-intestinal system smooth muscle contraction" NARROW [GOC:TermGenie]
synonym: "up regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "up-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "upregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie]
is_a: GO:0045987 ! positive regulation of smooth muscle contraction
is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction
relationship: positively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction
created_by: sl
creation_date: 2015-06-09T23:18:54Z

[Term]
id: GO:1904318
name: regulation of smooth muscle contraction involved in micturition
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635]
synonym: "regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
is_a: GO:0006940 ! regulation of smooth muscle contraction
is_a: GO:0044062 ! regulation of excretion
is_a: GO:0098801 ! regulation of renal system process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060083 ! smooth muscle contraction involved in micturition
relationship: regulates GO:0060083 ! smooth muscle contraction involved in micturition
created_by: sl
creation_date: 2015-06-10T18:46:11Z

[Term]
id: GO:1904319
name: negative regulation of smooth muscle contraction involved in micturition
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635]
synonym: "down regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie]
synonym: "down regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "down regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
synonym: "down-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie]
synonym: "down-regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "down-regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
synonym: "downregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie]
synonym: "downregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "downregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
synonym: "inhibition of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie]
synonym: "inhibition of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "inhibition of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
synonym: "negative regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "negative regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
is_a: GO:0045986 ! negative regulation of smooth muscle contraction
is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060083 ! smooth muscle contraction involved in micturition
relationship: negatively_regulates GO:0060083 ! smooth muscle contraction involved in micturition
created_by: sl
creation_date: 2015-06-10T18:46:17Z

[Term]
id: GO:1904320
name: positive regulation of smooth muscle contraction involved in micturition
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635]
synonym: "activation of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie]
synonym: "activation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "activation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
synonym: "positive regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "positive regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
synonym: "up regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie]
synonym: "up regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "up regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
synonym: "up-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie]
synonym: "up-regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "up-regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
synonym: "upregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie]
synonym: "upregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie]
synonym: "upregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie]
is_a: GO:0045987 ! positive regulation of smooth muscle contraction
is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060083 ! smooth muscle contraction involved in micturition
relationship: positively_regulates GO:0060083 ! smooth muscle contraction involved in micturition
created_by: sl
creation_date: 2015-06-10T18:46:23Z

[Term]
id: GO:1904341
name: regulation of colon smooth muscle contraction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253]
is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1990765 ! colon smooth muscle contraction
relationship: regulates GO:1990765 ! colon smooth muscle contraction
created_by: sl
creation_date: 2015-06-11T21:16:58Z

[Term]
id: GO:1904342
name: negative regulation of colon smooth muscle contraction
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253]
synonym: "down regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "down-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "downregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "inhibition of colon smooth muscle contraction" NARROW [GOC:TermGenie]
is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction
is_a: GO:1904341 ! regulation of colon smooth muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1990765 ! colon smooth muscle contraction
relationship: negatively_regulates GO:1990765 ! colon smooth muscle contraction
created_by: sl
creation_date: 2015-06-11T21:17:05Z

[Term]
id: GO:1904343
name: positive regulation of colon smooth muscle contraction
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253]
synonym: "activation of colon smooth muscle contraction" NARROW [GOC:TermGenie]
synonym: "up regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "up-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "upregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie]
is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction
is_a: GO:1904341 ! regulation of colon smooth muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1990765 ! colon smooth muscle contraction
relationship: positively_regulates GO:1990765 ! colon smooth muscle contraction
created_by: sl
creation_date: 2015-06-11T21:17:11Z

[Term]
id: GO:1904344
name: regulation of gastric mucosal blood circulation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413]
synonym: "regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie]
is_a: GO:1903522 ! regulation of blood circulation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1990768 ! gastric mucosal blood circulation
relationship: regulates GO:1990768 ! gastric mucosal blood circulation
created_by: sl
creation_date: 2015-06-11T21:20:31Z

[Term]
id: GO:1904345
name: negative regulation of gastric mucosal blood circulation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413]
synonym: "down regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "down regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "down-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "down-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "downregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "downregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "inhibition of gastric mucosal blood circulation" NARROW [GOC:TermGenie]
synonym: "inhibition of stomach mucosal blood circulation" NARROW [GOC:TermGenie]
synonym: "negative regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie]
is_a: GO:1903523 ! negative regulation of blood circulation
is_a: GO:1904344 ! regulation of gastric mucosal blood circulation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1990768 ! gastric mucosal blood circulation
relationship: negatively_regulates GO:1990768 ! gastric mucosal blood circulation
created_by: sl
creation_date: 2015-06-11T21:20:44Z

[Term]
id: GO:1904346
name: positive regulation of gastric mucosal blood circulation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413]
synonym: "activation of gastric mucosal blood circulation" NARROW [GOC:TermGenie]
synonym: "activation of stomach mucosal blood circulation" NARROW [GOC:TermGenie]
synonym: "positive regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "up regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "up regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "up-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "up-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "upregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie]
synonym: "upregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie]
is_a: GO:1903524 ! positive regulation of blood circulation
is_a: GO:1904344 ! regulation of gastric mucosal blood circulation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1990768 ! gastric mucosal blood circulation
relationship: positively_regulates GO:1990768 ! gastric mucosal blood circulation
created_by: sl
creation_date: 2015-06-11T21:20:50Z

[Term]
id: GO:1904347
name: regulation of small intestine smooth muscle contraction
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626]
is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1990770 ! small intestine smooth muscle contraction
relationship: regulates GO:1990770 ! small intestine smooth muscle contraction
created_by: sl
creation_date: 2015-06-11T21:37:34Z

[Term]
id: GO:1904348
name: negative regulation of small intestine smooth muscle contraction
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626]
synonym: "down regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "down-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "downregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "inhibition of small intestine smooth muscle contraction" NARROW [GOC:TermGenie]
is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction
is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1990770 ! small intestine smooth muscle contraction
relationship: negatively_regulates GO:1990770 ! small intestine smooth muscle contraction
created_by: sl
creation_date: 2015-06-11T21:37:40Z

[Term]
id: GO:1904349
name: positive regulation of small intestine smooth muscle contraction
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626]
synonym: "activation of small intestine smooth muscle contraction" NARROW [GOC:TermGenie]
synonym: "up regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "up-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie]
synonym: "upregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie]
is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction
is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1990770 ! small intestine smooth muscle contraction
relationship: positively_regulates GO:1990770 ! small intestine smooth muscle contraction
created_by: sl
creation_date: 2015-06-11T21:37:46Z

[Term]
id: GO:1904350
name: regulation of protein catabolic process in the vacuole
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054]
synonym: "regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "regulation of vacuolar protein degradation" RELATED [GOC:TermGenie]
is_a: GO:0042176 ! regulation of protein catabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007039 ! protein catabolic process in the vacuole
relationship: regulates GO:0007039 ! protein catabolic process in the vacuole
created_by: rl
creation_date: 2015-06-12T09:10:36Z

[Term]
id: GO:1904351
name: negative regulation of protein catabolic process in the vacuole
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054]
synonym: "down regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie]
synonym: "down regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "down regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "down regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "down regulation of vacuolar protein degradation" RELATED [GOC:TermGenie]
synonym: "down-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie]
synonym: "down-regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "down-regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "down-regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "down-regulation of vacuolar protein degradation" RELATED [GOC:TermGenie]
synonym: "downregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie]
synonym: "downregulation of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "downregulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "downregulation of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "downregulation of vacuolar protein degradation" RELATED [GOC:TermGenie]
synonym: "inhibition of protein catabolic process in the vacuole" NARROW [GOC:TermGenie]
synonym: "inhibition of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "inhibition of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "inhibition of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "inhibition of vacuolar protein degradation" RELATED [GOC:TermGenie]
synonym: "negative regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "negative regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "negative regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "negative regulation of vacuolar protein degradation" RELATED [GOC:TermGenie]
is_a: GO:0042177 ! negative regulation of protein catabolic process
is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007039 ! protein catabolic process in the vacuole
relationship: negatively_regulates GO:0007039 ! protein catabolic process in the vacuole
created_by: rl
creation_date: 2015-06-12T09:10:42Z

[Term]
id: GO:1904352
name: positive regulation of protein catabolic process in the vacuole
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054]
synonym: "activation of protein catabolic process in the vacuole" NARROW [GOC:TermGenie]
synonym: "activation of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "activation of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "activation of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "activation of vacuolar protein degradation" RELATED [GOC:TermGenie]
synonym: "positive regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "positive regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "positive regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "positive regulation of vacuolar protein degradation" RELATED [GOC:TermGenie]
synonym: "up regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie]
synonym: "up regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "up regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "up regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "up regulation of vacuolar protein degradation" RELATED [GOC:TermGenie]
synonym: "up-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie]
synonym: "up-regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "up-regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "up-regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "up-regulation of vacuolar protein degradation" RELATED [GOC:TermGenie]
synonym: "upregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie]
synonym: "upregulation of vacuolar protein breakdown" RELATED [GOC:TermGenie]
synonym: "upregulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie]
synonym: "upregulation of vacuolar protein catabolism" RELATED [GOC:TermGenie]
synonym: "upregulation of vacuolar protein degradation" RELATED [GOC:TermGenie]
is_a: GO:0045732 ! positive regulation of protein catabolic process
is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007039 ! protein catabolic process in the vacuole
relationship: positively_regulates GO:0007039 ! protein catabolic process in the vacuole
created_by: rl
creation_date: 2015-06-12T09:10:49Z

[Term]
id: GO:1904375
name: regulation of protein localization to cell periphery
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290]
is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1990778 ! protein localization to cell periphery
relationship: regulates GO:1990778 ! protein localization to cell periphery
created_by: sl
creation_date: 2015-06-22T22:09:25Z

[Term]
id: GO:1904376
name: negative regulation of protein localization to cell periphery
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290]
synonym: "down regulation of protein localization to cell periphery" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to cell periphery" EXACT [GOC:TermGenie]
synonym: "inhibition of protein localization to cell periphery" NARROW [GOC:TermGenie]
is_a: GO:1903828 ! negative regulation of protein localization
is_a: GO:1904375 ! regulation of protein localization to cell periphery
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1990778 ! protein localization to cell periphery
relationship: negatively_regulates GO:1990778 ! protein localization to cell periphery
created_by: sl
creation_date: 2015-06-22T22:09:32Z

[Term]
id: GO:1904377
name: positive regulation of protein localization to cell periphery
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290]
synonym: "activation of protein localization to cell periphery" NARROW [GOC:TermGenie]
synonym: "up regulation of protein localization to cell periphery" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to cell periphery" EXACT [GOC:TermGenie]
is_a: GO:1903829 ! positive regulation of protein localization
is_a: GO:1904375 ! regulation of protein localization to cell periphery
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1990778 ! protein localization to cell periphery
relationship: positively_regulates GO:1990778 ! protein localization to cell periphery
created_by: sl
creation_date: 2015-06-22T22:09:37Z

[Term]
id: GO:1904396
name: regulation of neuromuscular junction development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643]
synonym: "regulation of neuromuscular junction organization" EXACT [GOC:TermGenie]
synonym: "regulation of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "regulation of NMJ stability" RELATED [GOC:TermGenie]
is_a: GO:0050807 ! regulation of synapse organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007528 ! neuromuscular junction development
relationship: regulates GO:0007528 ! neuromuscular junction development
created_by: sl
creation_date: 2015-06-23T19:23:42Z

[Term]
id: GO:1904397
name: negative regulation of neuromuscular junction development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643]
synonym: "down regulation of neuromuscular junction development" EXACT [GOC:TermGenie]
synonym: "down regulation of neuromuscular junction organization" EXACT [GOC:TermGenie]
synonym: "down regulation of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "down regulation of NMJ stability" RELATED [GOC:TermGenie]
synonym: "down-regulation of neuromuscular junction development" EXACT [GOC:TermGenie]
synonym: "down-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie]
synonym: "down-regulation of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "down-regulation of NMJ stability" RELATED [GOC:TermGenie]
synonym: "downregulation of neuromuscular junction development" EXACT [GOC:TermGenie]
synonym: "downregulation of neuromuscular junction organization" EXACT [GOC:TermGenie]
synonym: "downregulation of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "downregulation of NMJ stability" RELATED [GOC:TermGenie]
synonym: "inhibition of neuromuscular junction development" NARROW [GOC:TermGenie]
synonym: "inhibition of neuromuscular junction organization" NARROW [GOC:TermGenie]
synonym: "inhibition of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "inhibition of NMJ stability" RELATED [GOC:TermGenie]
synonym: "negative regulation of neuromuscular junction organization" EXACT [GOC:TermGenie]
synonym: "negative regulation of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "negative regulation of NMJ stability" RELATED [GOC:TermGenie]
is_a: GO:1904396 ! regulation of neuromuscular junction development
is_a: GO:1905809 ! negative regulation of synapse organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007528 ! neuromuscular junction development
relationship: negatively_regulates GO:0007528 ! neuromuscular junction development
created_by: sl
creation_date: 2015-06-23T19:23:48Z

[Term]
id: GO:1904398
name: positive regulation of neuromuscular junction development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643]
synonym: "activation of neuromuscular junction development" NARROW [GOC:TermGenie]
synonym: "activation of neuromuscular junction organization" NARROW [GOC:TermGenie]
synonym: "activation of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "activation of NMJ stability" RELATED [GOC:TermGenie]
synonym: "positive regulation of neuromuscular junction organization" EXACT [GOC:TermGenie]
synonym: "positive regulation of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "positive regulation of NMJ stability" RELATED [GOC:TermGenie]
synonym: "up regulation of neuromuscular junction development" EXACT [GOC:TermGenie]
synonym: "up regulation of neuromuscular junction organization" EXACT [GOC:TermGenie]
synonym: "up regulation of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "up regulation of NMJ stability" RELATED [GOC:TermGenie]
synonym: "up-regulation of neuromuscular junction development" EXACT [GOC:TermGenie]
synonym: "up-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie]
synonym: "up-regulation of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "up-regulation of NMJ stability" RELATED [GOC:TermGenie]
synonym: "upregulation of neuromuscular junction development" EXACT [GOC:TermGenie]
synonym: "upregulation of neuromuscular junction organization" EXACT [GOC:TermGenie]
synonym: "upregulation of neuromuscular junction stability" RELATED [GOC:TermGenie]
synonym: "upregulation of NMJ stability" RELATED [GOC:TermGenie]
is_a: GO:0051130 ! positive regulation of cellular component organization
is_a: GO:1904396 ! regulation of neuromuscular junction development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007528 ! neuromuscular junction development
relationship: positively_regulates GO:0007528 ! neuromuscular junction development
created_by: sl
creation_date: 2015-06-23T19:23:54Z

[Term]
id: GO:1904409
name: regulation of secretory granule organization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777]
synonym: "regulation of secretory granule organisation" EXACT [GOC:TermGenie]
synonym: "regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0033043 ! regulation of organelle organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0033363 ! secretory granule organization
relationship: regulates GO:0033363 ! secretory granule organization
created_by: sl
creation_date: 2015-06-25T19:40:42Z

[Term]
id: GO:1904410
name: negative regulation of secretory granule organization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777]
synonym: "down regulation of secretory granule organisation" EXACT [GOC:TermGenie]
synonym: "down regulation of secretory granule organization" EXACT [GOC:TermGenie]
synonym: "down regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "down-regulation of secretory granule organisation" EXACT [GOC:TermGenie]
synonym: "down-regulation of secretory granule organization" EXACT [GOC:TermGenie]
synonym: "down-regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "downregulation of secretory granule organisation" EXACT [GOC:TermGenie]
synonym: "downregulation of secretory granule organization" EXACT [GOC:TermGenie]
synonym: "downregulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "inhibition of secretory granule organisation" NARROW [GOC:TermGenie]
synonym: "inhibition of secretory granule organization" NARROW [GOC:TermGenie]
synonym: "inhibition of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "negative regulation of secretory granule organisation" EXACT [GOC:TermGenie]
synonym: "negative regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0010639 ! negative regulation of organelle organization
is_a: GO:1904409 ! regulation of secretory granule organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0033363 ! secretory granule organization
relationship: negatively_regulates GO:0033363 ! secretory granule organization
created_by: sl
creation_date: 2015-06-25T19:40:49Z

[Term]
id: GO:1904411
name: positive regulation of secretory granule organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777]
synonym: "activation of secretory granule organisation" NARROW [GOC:TermGenie]
synonym: "activation of secretory granule organization" NARROW [GOC:TermGenie]
synonym: "activation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "positive regulation of secretory granule organisation" EXACT [GOC:TermGenie]
synonym: "positive regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "up regulation of secretory granule organisation" EXACT [GOC:TermGenie]
synonym: "up regulation of secretory granule organization" EXACT [GOC:TermGenie]
synonym: "up regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "up-regulation of secretory granule organisation" EXACT [GOC:TermGenie]
synonym: "up-regulation of secretory granule organization" EXACT [GOC:TermGenie]
synonym: "up-regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "upregulation of secretory granule organisation" EXACT [GOC:TermGenie]
synonym: "upregulation of secretory granule organization" EXACT [GOC:TermGenie]
synonym: "upregulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:1904409 ! regulation of secretory granule organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0033363 ! secretory granule organization
relationship: positively_regulates GO:0033363 ! secretory granule organization
created_by: sl
creation_date: 2015-06-25T19:40:55Z

[Term]
id: GO:1904412
name: regulation of cardiac ventricle development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003231 ! cardiac ventricle development
relationship: regulates GO:0003231 ! cardiac ventricle development
created_by: sl
creation_date: 2015-06-25T19:52:15Z

[Term]
id: GO:1904413
name: negative regulation of cardiac ventricle development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510]
synonym: "down regulation of cardiac ventricle development" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiac ventricle development" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiac ventricle development" EXACT [GOC:TermGenie]
synonym: "inhibition of cardiac ventricle development" NARROW [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1904412 ! regulation of cardiac ventricle development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003231 ! cardiac ventricle development
relationship: negatively_regulates GO:0003231 ! cardiac ventricle development
created_by: sl
creation_date: 2015-06-25T19:52:21Z

[Term]
id: GO:1904414
name: positive regulation of cardiac ventricle development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510]
synonym: "activation of cardiac ventricle development" NARROW [GOC:TermGenie]
synonym: "up regulation of cardiac ventricle development" EXACT [GOC:TermGenie]
synonym: "up-regulation of cardiac ventricle development" EXACT [GOC:TermGenie]
synonym: "upregulation of cardiac ventricle development" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1904412 ! regulation of cardiac ventricle development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003231 ! cardiac ventricle development
relationship: positively_regulates GO:0003231 ! cardiac ventricle development
created_by: sl
creation_date: 2015-06-25T19:52:27Z

[Term]
id: GO:1904456
name: negative regulation of neuronal action potential
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967]
synonym: "down regulation of generation of action potential" RELATED [GOC:TermGenie]
synonym: "down regulation of neuronal action potential" EXACT [GOC:TermGenie]
synonym: "down-regulation of generation of action potential" RELATED [GOC:TermGenie]
synonym: "down-regulation of neuronal action potential" EXACT [GOC:TermGenie]
synonym: "downregulation of generation of action potential" RELATED [GOC:TermGenie]
synonym: "downregulation of neuronal action potential" EXACT [GOC:TermGenie]
synonym: "inhibition of generation of action potential" RELATED [GOC:TermGenie]
synonym: "inhibition of neuronal action potential" NARROW [GOC:TermGenie]
synonym: "negative regulation of generation of action potential" RELATED [GOC:TermGenie]
is_a: GO:0045759 ! negative regulation of action potential
is_a: GO:0051970 ! negative regulation of transmission of nerve impulse
is_a: GO:0098908 ! regulation of neuronal action potential
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0019228 ! neuronal action potential
relationship: negatively_regulates GO:0019228 ! neuronal action potential
created_by: sl
creation_date: 2015-07-09T18:02:40Z

[Term]
id: GO:1904457
name: positive regulation of neuronal action potential
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967]
synonym: "activation of generation of action potential" RELATED [GOC:TermGenie]
synonym: "activation of neuronal action potential" NARROW [GOC:TermGenie]
synonym: "positive regulation of generation of action potential" RELATED [GOC:TermGenie]
synonym: "up regulation of generation of action potential" RELATED [GOC:TermGenie]
synonym: "up regulation of neuronal action potential" EXACT [GOC:TermGenie]
synonym: "up-regulation of generation of action potential" RELATED [GOC:TermGenie]
synonym: "up-regulation of neuronal action potential" EXACT [GOC:TermGenie]
synonym: "upregulation of generation of action potential" RELATED [GOC:TermGenie]
synonym: "upregulation of neuronal action potential" EXACT [GOC:TermGenie]
is_a: GO:0045760 ! positive regulation of action potential
is_a: GO:0051971 ! positive regulation of transmission of nerve impulse
is_a: GO:0098908 ! regulation of neuronal action potential
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0019228 ! neuronal action potential
relationship: positively_regulates GO:0019228 ! neuronal action potential
created_by: sl
creation_date: 2015-07-09T18:02:46Z

[Term]
id: GO:1904484
name: cloacal gland development
namespace: biological_process
def: "The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:mr, GOC:TermGenie, PMID:18805421]
is_a: GO:0048732 ! gland development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0012478 ! cloacal gland
relationship: results_in_development_of UBERON:0012478 ! cloacal gland
created_by: mr
creation_date: 2015-07-15T22:14:39Z

[Term]
id: GO:1904491
name: protein localization to ciliary transition zone
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:21422230]
synonym: "protein localisation in ciliary transition zone" EXACT [GOC:TermGenie]
synonym: "protein localisation to ciliary transition zone" EXACT [GOC:TermGenie]
synonym: "protein localization in ciliary transition zone" EXACT [GOC:TermGenie]
is_a: GO:0061512 ! protein localization to cilium
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0035869 ! ciliary transition zone
relationship: has_target_end_location GO:0035869 ! ciliary transition zone
created_by: kmv
creation_date: 2015-07-17T20:43:21Z

[Term]
id: GO:1904587
name: response to glycoprotein
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422]
synonym: "response to glycoproteins" EXACT []
is_a: GO:0010033 ! response to organic substance
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:17089 ! glycoprotein
relationship: has_primary_input CHEBI:17089 ! glycoprotein
created_by: sl
creation_date: 2015-08-20T16:46:24Z

[Term]
id: GO:1904606
name: fat cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a fat cell." [GO_REF:0000085, GOC:TermGenie, PMID:17024416]
synonym: "adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "adipocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "adipose cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "fat cell apoptosis" NARROW [GOC:TermGenie]
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000136 ! adipocyte
relationship: occurs_in CL:0000136 ! adipocyte
created_by: sl
creation_date: 2015-08-27T18:13:06Z

[Term]
id: GO:1904649
name: regulation of fat cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416]
synonym: "regulation of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "regulation of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "regulation of fat cell apoptosis" NARROW [GOC:TermGenie]
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1904606 ! fat cell apoptotic process
relationship: regulates GO:1904606 ! fat cell apoptotic process
created_by: sl
creation_date: 2015-08-31T20:59:28Z

[Term]
id: GO:1904650
name: negative regulation of fat cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416]
synonym: "down regulation of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "down regulation of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down regulation of fat cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of fat cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of fat cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of fat cell apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of fat cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "inhibition of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of adipocyte apoptotic process" NARROW [GOC:TermGenie]
synonym: "inhibition of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of adipose cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "inhibition of fat cell apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of fat cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "negative regulation of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "negative regulation of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "negative regulation of fat cell apoptosis" NARROW [GOC:TermGenie]
is_a: GO:0043066 ! negative regulation of apoptotic process
is_a: GO:1904649 ! regulation of fat cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1904606 ! fat cell apoptotic process
relationship: negatively_regulates GO:1904606 ! fat cell apoptotic process
created_by: sl
creation_date: 2015-08-31T20:59:34Z

[Term]
id: GO:1904651
name: positive regulation of fat cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416]
synonym: "activation of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of adipocyte apoptotic process" NARROW [GOC:TermGenie]
synonym: "activation of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of adipose cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "activation of fat cell apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of fat cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "positive regulation of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "positive regulation of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "positive regulation of fat cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of fat cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of fat cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of fat cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of adipocyte apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of adipose cell apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of fat cell apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of fat cell apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0043065 ! positive regulation of apoptotic process
is_a: GO:1904649 ! regulation of fat cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1904606 ! fat cell apoptotic process
relationship: positively_regulates GO:1904606 ! fat cell apoptotic process
created_by: sl
creation_date: 2015-08-31T20:59:40Z

[Term]
id: GO:1904659
name: glucose transmembrane transport
namespace: biological_process
alt_id: GO:0015758
def: "The process in which glucose is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:9090050]
synonym: "glucose transport" RELATED []
is_a: GO:0008645 ! hexose transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:17234 ! glucose
intersection_of: results_in_transport_across GO:0016020 ! membrane
relationship: has_primary_input CHEBI:17234 ! glucose
created_by: vw
creation_date: 2015-09-04T17:20:16Z

[Term]
id: GO:1904671
name: negative regulation of cell differentiation involved in stem cell population maintenance
namespace: biological_process
def: "Any negative regulation of cell differentiation that is involved in stem cell population maintenance." [GO_REF:0000060, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607]
synonym: "down regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "down regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie]
synonym: "down-regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "down-regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie]
synonym: "downregulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "downregulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie]
synonym: "inhibition of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie]
synonym: "inhibition of cell differentiation involved in stem cell population maintenance" NARROW [GOC:TermGenie]
synonym: "negative regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie]
is_a: GO:0045596 ! negative regulation of cell differentiation
intersection_of: GO:0045596 ! negative regulation of cell differentiation
intersection_of: part_of GO:0019827 ! stem cell population maintenance
relationship: part_of GO:0019827 ! stem cell population maintenance
created_by: tb
creation_date: 2015-09-12T00:46:08Z

[Term]
id: GO:1904672
name: regulation of somatic stem cell population maintenance
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607]
is_a: GO:2000036 ! regulation of stem cell population maintenance
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035019 ! somatic stem cell population maintenance
relationship: regulates GO:0035019 ! somatic stem cell population maintenance
created_by: rph
creation_date: 2015-09-14T08:40:19Z

[Term]
id: GO:1904673
name: negative regulation of somatic stem cell population maintenance
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607]
synonym: "down regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie]
synonym: "down-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie]
synonym: "downregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie]
synonym: "inhibition of somatic stem cell population maintenance" NARROW [GOC:TermGenie]
is_a: GO:1902455 ! negative regulation of stem cell population maintenance
is_a: GO:1904672 ! regulation of somatic stem cell population maintenance
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035019 ! somatic stem cell population maintenance
relationship: negatively_regulates GO:0035019 ! somatic stem cell population maintenance
created_by: rph
creation_date: 2015-09-14T08:40:25Z

[Term]
id: GO:1904674
name: positive regulation of somatic stem cell population maintenance
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607]
synonym: "activation of somatic stem cell population maintenance" NARROW [GOC:TermGenie]
synonym: "up regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie]
synonym: "up-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie]
synonym: "upregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie]
is_a: GO:1902459 ! positive regulation of stem cell population maintenance
is_a: GO:1904672 ! regulation of somatic stem cell population maintenance
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035019 ! somatic stem cell population maintenance
relationship: positively_regulates GO:0035019 ! somatic stem cell population maintenance
created_by: rph
creation_date: 2015-09-14T08:40:32Z

[Term]
id: GO:1904675
name: regulation of somatic stem cell division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607]
synonym: "regulation of somatic stem cell renewal" EXACT [GOC:TermGenie]
is_a: GO:2000035 ! regulation of stem cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048103 ! somatic stem cell division
relationship: regulates GO:0048103 ! somatic stem cell division
created_by: rph
creation_date: 2015-09-14T08:47:22Z

[Term]
id: GO:1904676
name: negative regulation of somatic stem cell division
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607]
synonym: "down regulation of somatic stem cell division" EXACT [GOC:TermGenie]
synonym: "down regulation of somatic stem cell renewal" EXACT [GOC:TermGenie]
synonym: "down-regulation of somatic stem cell division" EXACT [GOC:TermGenie]
synonym: "down-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie]
synonym: "downregulation of somatic stem cell division" EXACT [GOC:TermGenie]
synonym: "downregulation of somatic stem cell renewal" EXACT [GOC:TermGenie]
synonym: "inhibition of somatic stem cell division" NARROW [GOC:TermGenie]
synonym: "inhibition of somatic stem cell renewal" NARROW [GOC:TermGenie]
synonym: "negative regulation of somatic stem cell renewal" EXACT [GOC:TermGenie]
is_a: GO:0051782 ! negative regulation of cell division
is_a: GO:1904675 ! regulation of somatic stem cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048103 ! somatic stem cell division
relationship: negatively_regulates GO:0048103 ! somatic stem cell division
created_by: rph
creation_date: 2015-09-14T08:47:28Z

[Term]
id: GO:1904677
name: positive regulation of somatic stem cell division
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607]
synonym: "activation of somatic stem cell division" NARROW [GOC:TermGenie]
synonym: "activation of somatic stem cell renewal" NARROW [GOC:TermGenie]
synonym: "positive regulation of somatic stem cell renewal" EXACT [GOC:TermGenie]
synonym: "up regulation of somatic stem cell division" EXACT [GOC:TermGenie]
synonym: "up regulation of somatic stem cell renewal" EXACT [GOC:TermGenie]
synonym: "up-regulation of somatic stem cell division" EXACT [GOC:TermGenie]
synonym: "up-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie]
synonym: "upregulation of somatic stem cell division" EXACT [GOC:TermGenie]
synonym: "upregulation of somatic stem cell renewal" EXACT [GOC:TermGenie]
is_a: GO:0051781 ! positive regulation of cell division
is_a: GO:1904675 ! regulation of somatic stem cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048103 ! somatic stem cell division
relationship: positively_regulates GO:0048103 ! somatic stem cell division
created_by: rph
creation_date: 2015-09-14T08:47:34Z

[Term]
id: GO:1904680
name: peptide transmembrane transporter activity
namespace: molecular_function
alt_id: GO:0015197
alt_id: GO:0015637
def: "Enables the transfer of a peptide from one side of a membrane to the other." [GO_REF:0000070, GOC:TermGenie, GOC:vw]
synonym: "peptide transporter activity" RELATED []
synonym: "peptide uptake permease activity" RELATED []
xref: Reactome:R-HSA-1500817 "Glutathione is taken up by the bacterium"
is_a: GO:0042887 ! amide transmembrane transporter activity
intersection_of: GO:0005215 ! transporter activity
intersection_of: has_primary_input CHEBI:16670 ! peptide
intersection_of: results_in_transport_across GO:0016020 ! membrane
relationship: has_primary_input CHEBI:16670 ! peptide
created_by: tb
creation_date: 2015-09-22T18:50:41Z

[Term]
id: GO:1904691
name: negative regulation of type B pancreatic cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447]
synonym: "down regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie]
synonym: "down regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie]
synonym: "down regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie]
synonym: "inhibition of pancreatic B cell proliferation" NARROW [GOC:TermGenie]
synonym: "inhibition of pancreatic beta cell proliferation" NARROW [GOC:TermGenie]
synonym: "inhibition of type B pancreatic cell proliferation" NARROW [GOC:TermGenie]
synonym: "negative regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie]
synonym: "negative regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0050680 ! negative regulation of epithelial cell proliferation
is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0044342 ! type B pancreatic cell proliferation
relationship: negatively_regulates GO:0044342 ! type B pancreatic cell proliferation
created_by: sl
creation_date: 2015-09-25T15:23:38Z

[Term]
id: GO:1904692
name: positive regulation of type B pancreatic cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447]
synonym: "activation of pancreatic B cell proliferation" NARROW [GOC:TermGenie]
synonym: "activation of pancreatic beta cell proliferation" NARROW [GOC:TermGenie]
synonym: "activation of type B pancreatic cell proliferation" NARROW [GOC:TermGenie]
synonym: "positive regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie]
synonym: "positive regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0050679 ! positive regulation of epithelial cell proliferation
is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0044342 ! type B pancreatic cell proliferation
relationship: positively_regulates GO:0044342 ! type B pancreatic cell proliferation
created_by: sl
creation_date: 2015-09-25T15:23:44Z

[Term]
id: GO:1904693
name: midbrain morphogenesis
namespace: biological_process
def: "The developmental process by which a midbrain is generated and organized." [GO_REF:0000083, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21347250]
synonym: "MB morphogenesis" BROAD [GOC:TermGenie]
synonym: "mesencephalon morphogenesis" RELATED [GOC:TermGenie]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0001891 ! midbrain
relationship: part_of GO:0030901 ! midbrain development
relationship: part_of GO:0048854 ! brain morphogenesis
relationship: results_in_morphogenesis_of UBERON:0001891 ! midbrain
created_by: bf
creation_date: 2015-09-29T09:15:28Z

[Term]
id: GO:1904697
name: regulation of acinar cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538]
synonym: "regulation of acinic cell proliferation" EXACT [GOC:TermGenie]
synonym: "regulation of acinous cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0050678 ! regulation of epithelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1990863 ! acinar cell proliferation
relationship: regulates GO:1990863 ! acinar cell proliferation
created_by: sl
creation_date: 2015-09-30T15:19:50Z

[Term]
id: GO:1904698
name: negative regulation of acinar cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538]
synonym: "down regulation of acinar cell proliferation" EXACT [GOC:TermGenie]
synonym: "down regulation of acinic cell proliferation" EXACT [GOC:TermGenie]
synonym: "down regulation of acinous cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of acinar cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of acinic cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of acinous cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of acinar cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of acinic cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of acinous cell proliferation" EXACT [GOC:TermGenie]
synonym: "inhibition of acinar cell proliferation" NARROW [GOC:TermGenie]
synonym: "inhibition of acinic cell proliferation" NARROW [GOC:TermGenie]
synonym: "inhibition of acinous cell proliferation" NARROW [GOC:TermGenie]
synonym: "negative regulation of acinic cell proliferation" EXACT [GOC:TermGenie]
synonym: "negative regulation of acinous cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0050680 ! negative regulation of epithelial cell proliferation
is_a: GO:1904697 ! regulation of acinar cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1990863 ! acinar cell proliferation
relationship: negatively_regulates GO:1990863 ! acinar cell proliferation
created_by: sl
creation_date: 2015-09-30T15:19:57Z

[Term]
id: GO:1904699
name: positive regulation of acinar cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538]
synonym: "activation of acinar cell proliferation" NARROW [GOC:TermGenie]
synonym: "activation of acinic cell proliferation" NARROW [GOC:TermGenie]
synonym: "activation of acinous cell proliferation" NARROW [GOC:TermGenie]
synonym: "positive regulation of acinic cell proliferation" EXACT [GOC:TermGenie]
synonym: "positive regulation of acinous cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of acinar cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of acinic cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of acinous cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of acinar cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of acinic cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of acinous cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of acinar cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of acinic cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of acinous cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0050679 ! positive regulation of epithelial cell proliferation
is_a: GO:1904697 ! regulation of acinar cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1990863 ! acinar cell proliferation
relationship: positively_regulates GO:1990863 ! acinar cell proliferation
created_by: sl
creation_date: 2015-09-30T15:20:03Z

[Term]
id: GO:1904705
name: regulation of vascular associated smooth muscle cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467]
synonym: "regulation of vascular smooth muscle cell proliferation" EXACT []
synonym: "regulation of VSMC proliferation" EXACT [GOC:TermGenie]
is_a: GO:0048660 ! regulation of smooth muscle cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1990874 ! vascular associated smooth muscle cell proliferation
relationship: regulates GO:1990874 ! vascular associated smooth muscle cell proliferation
created_by: sl
creation_date: 2015-10-01T16:05:20Z

[Term]
id: GO:1904706
name: negative regulation of vascular associated smooth muscle cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467]
synonym: "down regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie]
synonym: "down regulation of VSMC proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of VSMC proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of VSMC proliferation" EXACT [GOC:TermGenie]
synonym: "inhibition of vascular smooth muscle cell proliferation" NARROW [GOC:TermGenie]
synonym: "inhibition of VSMC proliferation" NARROW [GOC:TermGenie]
synonym: "negative regulation of vascular smooth muscle cell proliferation" EXACT []
synonym: "negative regulation of VSMC proliferation" EXACT [GOC:TermGenie]
is_a: GO:0048662 ! negative regulation of smooth muscle cell proliferation
is_a: GO:1904705 ! regulation of vascular associated smooth muscle cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation
relationship: negatively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation
created_by: sl
creation_date: 2015-10-01T16:05:26Z

[Term]
id: GO:1904707
name: positive regulation of vascular associated smooth muscle cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467]
synonym: "activation of vascular smooth muscle cell proliferation" NARROW [GOC:TermGenie]
synonym: "activation of VSMC proliferation" NARROW [GOC:TermGenie]
synonym: "positive regulation of vascular smooth muscle cell proliferation" EXACT []
synonym: "positive regulation of VSMC proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie]
synonym: "up regulation of VSMC proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of VSMC proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of VSMC proliferation" EXACT [GOC:TermGenie]
is_a: GO:0048661 ! positive regulation of smooth muscle cell proliferation
is_a: GO:1904705 ! regulation of vascular associated smooth muscle cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation
relationship: positively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation
created_by: sl
creation_date: 2015-10-01T16:05:32Z

[Term]
id: GO:1904738
name: vascular associated smooth muscle cell migration
namespace: biological_process
def: "The orderly movement of a vascular associated smooth muscle cell from one site to another." [GO_REF:0000091, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317]
synonym: "vascular smooth muscle cell migration" EXACT []
is_a: GO:0014909 ! smooth muscle cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000359 ! vascular associated smooth muscle cell
relationship: results_in_movement_of CL:0000359 ! vascular associated smooth muscle cell
created_by: rph
creation_date: 2015-10-15T09:56:00Z

[Term]
id: GO:1904746
name: negative regulation of apoptotic process involved in development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495]
comment: U4PR86 in PMID:22801495 inferred from mutant phenotype
synonym: "down regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "down regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "down regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "down regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic process involved in development" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "down regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "down regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "down regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "down regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "down regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "down regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "down regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "down regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "down regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "down regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "down regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "down regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "down regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "down-regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "down-regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "down-regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "down-regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "down-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "down-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "down-regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "down-regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "down-regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "down-regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "down-regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "down-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "down-regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "down-regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "down-regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "downregulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "downregulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "downregulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "downregulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic process involved in development" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "downregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "downregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "downregulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "downregulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "downregulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "downregulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "downregulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "downregulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "downregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "downregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "downregulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "downregulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "downregulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "inhibition of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "inhibition of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "inhibition of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "inhibition of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic process involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic process involved in development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic process involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "inhibition of apoptotic programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "inhibition of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "inhibition of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "inhibition of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "inhibition of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "inhibition of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "inhibition of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "inhibition of programmed cell death by apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "inhibition of programmed cell death by apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "inhibition of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "inhibition of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "inhibition of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "negative regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "negative regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "negative regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "negative regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "negative regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "negative regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "negative regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "negative regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "negative regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "negative regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "negative regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "negative regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "negative regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "negative regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "negative regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "negative regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "negative regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "negative regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "negative regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
is_a: GO:0043066 ! negative regulation of apoptotic process
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:1904748 ! regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1902742 ! apoptotic process involved in development
relationship: negatively_regulates GO:1902742 ! apoptotic process involved in development
created_by: es
creation_date: 2015-10-19T14:12:27Z

[Term]
id: GO:1904747
name: positive regulation of apoptotic process involved in development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495]
comment: U4PR86 in PMID:22801495 inferred from mutant phenotype
synonym: "activation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "activation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "activation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "activation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "activation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "activation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic process involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic process involved in development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic process involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "activation of apoptotic programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "activation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "activation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "activation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "activation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "activation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "activation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "activation of programmed cell death by apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "activation of programmed cell death by apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "activation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "activation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "activation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "activation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "positive regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "positive regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "positive regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "positive regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "positive regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "positive regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "positive regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "positive regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "positive regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "positive regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "positive regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "positive regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "positive regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "positive regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "positive regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "positive regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "positive regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "positive regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "positive regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "up regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "up regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "up regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "up regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic process involved in development" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "up regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "up regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "up regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "up regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "up regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "up regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "up regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "up regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "up regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "up regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "up regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "up regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "up regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "up-regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "up-regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "up-regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "up-regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "up-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "up-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "up-regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "up-regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "up-regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "up-regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "up-regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "up-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "up-regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "up-regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "up-regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "upregulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "upregulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "upregulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "upregulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic process involved in development" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "upregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "upregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "upregulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "upregulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "upregulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "upregulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "upregulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "upregulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "upregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "upregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "upregulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "upregulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "upregulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
is_a: GO:0043065 ! positive regulation of apoptotic process
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:1904748 ! regulation of apoptotic process involved in development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1902742 ! apoptotic process involved in development
relationship: positively_regulates GO:1902742 ! apoptotic process involved in development
created_by: es
creation_date: 2015-10-19T14:12:34Z

[Term]
id: GO:1904748
name: regulation of apoptotic process involved in development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495]
comment: Q10943 in PMID:22801495, inferred from mutant phenotype
synonym: "regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie]
synonym: "regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie]
synonym: "regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie]
synonym: "regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie]
synonym: "regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie]
synonym: "regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie]
synonym: "regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie]
is_a: GO:0042981 ! regulation of apoptotic process
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1902742 ! apoptotic process involved in development
relationship: regulates GO:1902742 ! apoptotic process involved in development
created_by: es
creation_date: 2015-10-19T15:02:28Z

[Term]
id: GO:1904749
name: regulation of protein localization to nucleolus
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760]
synonym: "regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie]
synonym: "regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie]
synonym: "regulation of protein localization in nucleolus" EXACT [GOC:TermGenie]
is_a: GO:1900180 ! regulation of protein localization to nucleus
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1902570 ! protein localization to nucleolus
relationship: regulates GO:1902570 ! protein localization to nucleolus
created_by: nc
creation_date: 2015-10-19T15:16:17Z

[Term]
id: GO:1904750
name: negative regulation of protein localization to nucleolus
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760]
synonym: "down regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization in nucleolus" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization to nucleolus" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization in nucleolus" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to nucleolus" EXACT [GOC:TermGenie]
synonym: "inhibition of protein localisation in nucleolus" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localisation to nucleolus" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization in nucleolus" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization to nucleolus" NARROW [GOC:TermGenie]
synonym: "negative regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localization in nucleolus" EXACT [GOC:TermGenie]
is_a: GO:1900181 ! negative regulation of protein localization to nucleus
is_a: GO:1904749 ! regulation of protein localization to nucleolus
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1902570 ! protein localization to nucleolus
relationship: negatively_regulates GO:1902570 ! protein localization to nucleolus
created_by: nc
creation_date: 2015-10-19T15:16:24Z

[Term]
id: GO:1904751
name: positive regulation of protein localization to nucleolus
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760]
synonym: "activation of protein localisation in nucleolus" NARROW [GOC:TermGenie]
synonym: "activation of protein localisation to nucleolus" NARROW [GOC:TermGenie]
synonym: "activation of protein localization in nucleolus" NARROW [GOC:TermGenie]
synonym: "activation of protein localization to nucleolus" NARROW [GOC:TermGenie]
synonym: "positive regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localization in nucleolus" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization in nucleolus" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization to nucleolus" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization in nucleolus" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to nucleolus" EXACT [GOC:TermGenie]
is_a: GO:1900182 ! positive regulation of protein localization to nucleus
is_a: GO:1904749 ! regulation of protein localization to nucleolus
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1902570 ! protein localization to nucleolus
relationship: positively_regulates GO:1902570 ! protein localization to nucleolus
created_by: nc
creation_date: 2015-10-19T15:16:30Z

[Term]
id: GO:1904752
name: regulation of vascular associated smooth muscle cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317]
synonym: "regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie]
is_a: GO:0014910 ! regulation of smooth muscle cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1904738 ! vascular associated smooth muscle cell migration
relationship: regulates GO:1904738 ! vascular associated smooth muscle cell migration
created_by: rph
creation_date: 2015-10-19T15:49:52Z

[Term]
id: GO:1904753
name: negative regulation of vascular associated smooth muscle cell migration
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317]
synonym: "down regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "down regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "down-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "down-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "downregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "downregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "inhibition of vascular associated smooth muscle cell migration" NARROW [GOC:TermGenie]
synonym: "inhibition of vascular smooth muscle cell migration" NARROW [GOC:TermGenie]
synonym: "negative regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie]
is_a: GO:0014912 ! negative regulation of smooth muscle cell migration
is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1904738 ! vascular associated smooth muscle cell migration
relationship: negatively_regulates GO:1904738 ! vascular associated smooth muscle cell migration
created_by: rph
creation_date: 2015-10-19T15:49:58Z

[Term]
id: GO:1904754
name: positive regulation of vascular associated smooth muscle cell migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317]
synonym: "activation of vascular associated smooth muscle cell migration" NARROW [GOC:TermGenie]
synonym: "activation of vascular smooth muscle cell migration" NARROW [GOC:TermGenie]
synonym: "positive regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "up regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "up regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "up-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "up-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "upregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie]
synonym: "upregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie]
is_a: GO:0014911 ! positive regulation of smooth muscle cell migration
is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1904738 ! vascular associated smooth muscle cell migration
relationship: positively_regulates GO:1904738 ! vascular associated smooth muscle cell migration
created_by: rph
creation_date: 2015-10-19T15:50:05Z

[Term]
id: GO:1904770
name: intramembranous bone morphogenesis
namespace: biological_process
def: "The developmental process by which an intramembranous bone is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:26399686]
synonym: "intramembranous bones morphogenesis" RELATED [GOC:TermGenie]
synonym: "membrane bone morphogenesis" RELATED [GOC:TermGenie]
is_a: GO:0060349 ! bone morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002514 ! intramembranous bone
relationship: results_in_morphogenesis_of UBERON:0002514 ! intramembranous bone
created_by: dos
creation_date: 2015-10-28T11:46:04Z

[Term]
id: GO:1904776
name: regulation of protein localization to cell cortex
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027]
comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.
synonym: "regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie]
is_a: GO:1904375 ! regulation of protein localization to cell periphery
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072697 ! protein localization to cell cortex
relationship: regulates GO:0072697 ! protein localization to cell cortex
created_by: es
creation_date: 2015-10-29T16:55:01Z

[Term]
id: GO:1904777
name: negative regulation of protein localization to cell cortex
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027]
comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.
synonym: "down regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization to cell cortex" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to cell cortex" EXACT [GOC:TermGenie]
synonym: "inhibition of protein localisation to cell cortex" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization to cell cortex" NARROW [GOC:TermGenie]
synonym: "negative regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie]
is_a: GO:1904376 ! negative regulation of protein localization to cell periphery
is_a: GO:1904776 ! regulation of protein localization to cell cortex
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072697 ! protein localization to cell cortex
relationship: negatively_regulates GO:0072697 ! protein localization to cell cortex
created_by: es
creation_date: 2015-10-29T16:55:08Z

[Term]
id: GO:1904778
name: positive regulation of protein localization to cell cortex
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027]
comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.
synonym: "activation of protein localisation to cell cortex" NARROW [GOC:TermGenie]
synonym: "activation of protein localization to cell cortex" NARROW [GOC:TermGenie]
synonym: "positive regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization to cell cortex" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to cell cortex" EXACT [GOC:TermGenie]
is_a: GO:1904377 ! positive regulation of protein localization to cell periphery
is_a: GO:1904776 ! regulation of protein localization to cell cortex
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072697 ! protein localization to cell cortex
relationship: positively_regulates GO:0072697 ! protein localization to cell cortex
created_by: es
creation_date: 2015-10-29T16:55:15Z

[Term]
id: GO:1904817
name: serous membrane development
namespace: biological_process
def: "The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053]
synonym: "serosa development" RELATED [GOC:TermGenie]
synonym: "tunica serosa development" EXACT [GOC:TermGenie]
synonym: "wall of serous sac development" EXACT [GOC:TermGenie]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0000042 ! serous membrane
relationship: results_in_development_of UBERON:0000042 ! serous membrane
created_by: dph
creation_date: 2015-11-17T19:00:01Z

[Term]
id: GO:1904818
name: visceral peritoneum development
namespace: biological_process
def: "The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001178 ! visceral peritoneum
relationship: part_of GO:1904820 ! peritoneum development
relationship: results_in_development_of UBERON:0001178 ! visceral peritoneum
created_by: dph
creation_date: 2015-11-17T19:00:17Z

[Term]
id: GO:1904819
name: parietal peritoneum development
namespace: biological_process
def: "The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053]
synonym: "peritoneal cavity lining development" EXACT [GOC:TermGenie]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001366 ! parietal peritoneum
relationship: part_of GO:1904820 ! peritoneum development
relationship: results_in_development_of UBERON:0001366 ! parietal peritoneum
created_by: dph
creation_date: 2015-11-17T19:00:24Z

[Term]
id: GO:1904820
name: peritoneum development
namespace: biological_process
def: "The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053]
synonym: "peritonaeum development" RELATED [GOC:TermGenie]
is_a: GO:1904817 ! serous membrane development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0002358 ! peritoneum
relationship: results_in_development_of UBERON:0002358 ! peritoneum
created_by: dph
creation_date: 2015-11-18T17:23:51Z

[Term]
id: GO:1904829
name: regulation of aortic smooth muscle cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194]
is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035887 ! aortic smooth muscle cell differentiation
relationship: regulates GO:0035887 ! aortic smooth muscle cell differentiation
created_by: rph
creation_date: 2015-11-24T10:20:40Z

[Term]
id: GO:1904830
name: negative regulation of aortic smooth muscle cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194]
synonym: "down regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of aortic smooth muscle cell differentiation" NARROW [GOC:TermGenie]
is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation
is_a: GO:1905064 ! negative regulation of vascular associated smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035887 ! aortic smooth muscle cell differentiation
relationship: negatively_regulates GO:0035887 ! aortic smooth muscle cell differentiation
created_by: rph
creation_date: 2015-11-24T10:20:47Z

[Term]
id: GO:1904831
name: positive regulation of aortic smooth muscle cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194]
synonym: "activation of aortic smooth muscle cell differentiation" NARROW [GOC:TermGenie]
synonym: "up regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation
is_a: GO:1905065 ! positive regulation of vascular associated smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035887 ! aortic smooth muscle cell differentiation
relationship: positively_regulates GO:0035887 ! aortic smooth muscle cell differentiation
created_by: rph
creation_date: 2015-11-24T10:20:54Z

[Term]
id: GO:1904888
name: cranial skeletal system development
namespace: biological_process
def: "The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [GO_REF:0000094, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11262227]
synonym: "cranial skeleton development" NARROW [GOC:TermGenie]
synonym: "craniofacial development" NARROW [PMID:11262227]
synonym: "cranium development" RELATED [GOC:TermGenie]
synonym: "osteocranium development" NARROW [GOC:TermGenie]
is_a: GO:0048856 ! anatomical structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0010323 ! cranial skeletal system
relationship: results_in_development_of UBERON:0010323 ! cranial skeletal system
created_by: bf
creation_date: 2016-01-07T13:45:06Z

[Term]
id: GO:1904933
name: regulation of cell proliferation in midbrain
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302]
synonym: "regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie]
synonym: "regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
is_a: GO:2000177 ! regulation of neural precursor cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0033278 ! cell proliferation in midbrain
relationship: regulates GO:0033278 ! cell proliferation in midbrain
created_by: bf
creation_date: 2016-02-01T13:16:11Z

[Term]
id: GO:1904934
name: negative regulation of cell proliferation in midbrain
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302]
synonym: "down regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie]
synonym: "down regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie]
synonym: "down regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
synonym: "down-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie]
synonym: "down-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie]
synonym: "down-regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
synonym: "downregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie]
synonym: "downregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie]
synonym: "downregulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
synonym: "inhibition of cell proliferation in mesencephalon" NARROW [GOC:TermGenie]
synonym: "inhibition of cell proliferation in midbrain" NARROW [GOC:TermGenie]
synonym: "inhibition of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
synonym: "negative regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie]
synonym: "negative regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
is_a: GO:1904933 ! regulation of cell proliferation in midbrain
is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0033278 ! cell proliferation in midbrain
relationship: negatively_regulates GO:0033278 ! cell proliferation in midbrain
created_by: bf
creation_date: 2016-02-01T13:16:19Z

[Term]
id: GO:1904935
name: positive regulation of cell proliferation in midbrain
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24431302]
synonym: "activation of cell proliferation in mesencephalon" NARROW [GOC:TermGenie]
synonym: "activation of cell proliferation in midbrain" NARROW [GOC:TermGenie]
synonym: "activation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
synonym: "positive regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie]
synonym: "positive regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
synonym: "up regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie]
synonym: "up regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie]
synonym: "up regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
synonym: "up-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie]
synonym: "up-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie]
synonym: "up-regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
synonym: "upregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie]
synonym: "upregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie]
synonym: "upregulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie]
is_a: GO:1904933 ! regulation of cell proliferation in midbrain
is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0033278 ! cell proliferation in midbrain
relationship: positively_regulates GO:0033278 ! cell proliferation in midbrain
created_by: bf
creation_date: 2016-02-01T13:16:27Z

[Term]
id: GO:1904936
name: interneuron migration
namespace: biological_process
def: "The orderly movement of an interneuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031]
synonym: "inter neuron migration" EXACT [GOC:ah]
synonym: "inter-neuron migration" EXACT [GOC:ah]
is_a: GO:0001764 ! neuron migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000099 ! interneuron
relationship: results_in_movement_of CL:0000099 ! interneuron
created_by: ah
creation_date: 2016-02-01T14:04:32Z

[Term]
id: GO:1904937
name: sensory neuron migration
namespace: biological_process
def: "The orderly movement of a sensory neuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031]
is_a: GO:0001764 ! neuron migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000101 ! sensory neuron
relationship: results_in_movement_of CL:0000101 ! sensory neuron
created_by: ah
creation_date: 2016-02-01T14:15:50Z

[Term]
id: GO:1904942
name: regulation of cardiac ventricle formation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307]
is_a: GO:1901210 ! regulation of cardiac chamber formation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003211 ! cardiac ventricle formation
relationship: regulates GO:0003211 ! cardiac ventricle formation
created_by: bc
creation_date: 2016-02-02T16:37:16Z

[Term]
id: GO:1904943
name: negative regulation of cardiac ventricle formation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307]
synonym: "down regulation of cardiac ventricle formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiac ventricle formation" EXACT [GOC:TermGenie]
synonym: "inhibition of cardiac ventricle formation" NARROW [GOC:TermGenie]
is_a: GO:1901211 ! negative regulation of cardiac chamber formation
is_a: GO:1904413 ! negative regulation of cardiac ventricle development
is_a: GO:1904942 ! regulation of cardiac ventricle formation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003211 ! cardiac ventricle formation
relationship: negatively_regulates GO:0003211 ! cardiac ventricle formation
created_by: bc
creation_date: 2016-02-02T16:37:24Z

[Term]
id: GO:1904944
name: positive regulation of cardiac ventricle formation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307]
synonym: "activation of cardiac ventricle formation" NARROW [GOC:TermGenie]
synonym: "up regulation of cardiac ventricle formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie]
synonym: "upregulation of cardiac ventricle formation" EXACT [GOC:TermGenie]
is_a: GO:1901212 ! positive regulation of cardiac chamber formation
is_a: GO:1904942 ! regulation of cardiac ventricle formation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003211 ! cardiac ventricle formation
relationship: positively_regulates GO:0003211 ! cardiac ventricle formation
created_by: bc
creation_date: 2016-02-02T16:37:31Z

[Term]
id: GO:1904950
name: negative regulation of establishment of protein localization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445]
synonym: "down regulation of establishment of protein localisation" EXACT [GOC:TermGenie]
synonym: "down regulation of establishment of protein localization" EXACT [GOC:TermGenie]
synonym: "down regulation of protein positioning" EXACT [GOC:TermGenie]
synonym: "down regulation of protein recruitment" EXACT [GOC:TermGenie]
synonym: "down-regulation of establishment of protein localisation" EXACT [GOC:TermGenie]
synonym: "down-regulation of establishment of protein localization" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein positioning" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein recruitment" EXACT [GOC:TermGenie]
synonym: "downregulation of establishment of protein localisation" EXACT [GOC:TermGenie]
synonym: "downregulation of establishment of protein localization" EXACT [GOC:TermGenie]
synonym: "downregulation of protein positioning" EXACT [GOC:TermGenie]
synonym: "downregulation of protein recruitment" EXACT [GOC:TermGenie]
synonym: "inhibition of establishment of protein localisation" NARROW [GOC:TermGenie]
synonym: "inhibition of establishment of protein localization" NARROW [GOC:TermGenie]
synonym: "inhibition of protein positioning" NARROW [GOC:TermGenie]
synonym: "inhibition of protein recruitment" NARROW [GOC:TermGenie]
synonym: "negative regulation of establishment of protein localisation" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein positioning" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein recruitment" EXACT [GOC:TermGenie]
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:0070201 ! regulation of establishment of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045184 ! establishment of protein localization
relationship: negatively_regulates GO:0045184 ! establishment of protein localization
created_by: mec
creation_date: 2016-02-05T09:59:24Z

[Term]
id: GO:1904951
name: positive regulation of establishment of protein localization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445]
synonym: "activation of establishment of protein localisation" NARROW [GOC:TermGenie]
synonym: "activation of establishment of protein localization" NARROW [GOC:TermGenie]
synonym: "activation of protein positioning" NARROW [GOC:TermGenie]
synonym: "activation of protein recruitment" NARROW [GOC:TermGenie]
synonym: "positive regulation of establishment of protein localisation" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein positioning" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein recruitment" EXACT [GOC:TermGenie]
synonym: "up regulation of establishment of protein localisation" EXACT [GOC:TermGenie]
synonym: "up regulation of establishment of protein localization" EXACT [GOC:TermGenie]
synonym: "up regulation of protein positioning" EXACT [GOC:TermGenie]
synonym: "up regulation of protein recruitment" EXACT [GOC:TermGenie]
synonym: "up-regulation of establishment of protein localisation" EXACT [GOC:TermGenie]
synonym: "up-regulation of establishment of protein localization" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein positioning" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein recruitment" EXACT [GOC:TermGenie]
synonym: "upregulation of establishment of protein localisation" EXACT [GOC:TermGenie]
synonym: "upregulation of establishment of protein localization" EXACT [GOC:TermGenie]
synonym: "upregulation of protein positioning" EXACT [GOC:TermGenie]
synonym: "upregulation of protein recruitment" EXACT [GOC:TermGenie]
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:0070201 ! regulation of establishment of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0045184 ! establishment of protein localization
relationship: positively_regulates GO:0045184 ! establishment of protein localization
created_by: mec
creation_date: 2016-02-05T09:59:32Z

[Term]
id: GO:1904987
name: regulation of endothelial cell activation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059]
is_a: GO:0050865 ! regulation of cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042118 ! endothelial cell activation
relationship: regulates GO:0042118 ! endothelial cell activation
created_by: bc
creation_date: 2016-02-29T16:16:09Z

[Term]
id: GO:1904988
name: negative regulation of endothelial cell activation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059]
synonym: "down regulation of endothelial cell activation" EXACT [GOC:TermGenie]
synonym: "down-regulation of endothelial cell activation" EXACT [GOC:TermGenie]
synonym: "downregulation of endothelial cell activation" EXACT [GOC:TermGenie]
synonym: "inhibition of endothelial cell activation" NARROW [GOC:TermGenie]
is_a: GO:0050866 ! negative regulation of cell activation
is_a: GO:1904987 ! regulation of endothelial cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042118 ! endothelial cell activation
relationship: negatively_regulates GO:0042118 ! endothelial cell activation
created_by: bc
creation_date: 2016-02-29T16:16:18Z

[Term]
id: GO:1904989
name: positive regulation of endothelial cell activation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059]
synonym: "activation of endothelial cell activation" NARROW [GOC:TermGenie]
synonym: "up regulation of endothelial cell activation" EXACT [GOC:TermGenie]
synonym: "up-regulation of endothelial cell activation" EXACT [GOC:TermGenie]
synonym: "upregulation of endothelial cell activation" EXACT [GOC:TermGenie]
is_a: GO:0050867 ! positive regulation of cell activation
is_a: GO:1904987 ! regulation of endothelial cell activation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0042118 ! endothelial cell activation
relationship: positively_regulates GO:0042118 ! endothelial cell activation
created_by: bc
creation_date: 2016-02-29T16:16:25Z

[Term]
id: GO:1905039
name: carboxylic acid transmembrane transport
namespace: biological_process
def: "The process in which carboxylic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:10869563]
is_a: GO:0046942 ! carboxylic acid transport
is_a: GO:0055085 ! transmembrane transport
intersection_of: GO:0006810 ! transport
intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion
intersection_of: results_in_transport_across GO:0016020 ! membrane
created_by: vw
creation_date: 2016-03-09T15:33:53Z

[Term]
id: GO:1905063
name: regulation of vascular associated smooth muscle cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079]
synonym: "regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "regulation of VSMC differentiation" EXACT [GOC:TermGenie]
is_a: GO:0051150 ! regulation of smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035886 ! vascular associated smooth muscle cell differentiation
relationship: regulates GO:0035886 ! vascular associated smooth muscle cell differentiation
created_by: rph
creation_date: 2016-03-21T11:14:53Z

[Term]
id: GO:1905064
name: negative regulation of vascular associated smooth muscle cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079]
synonym: "down regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of VSMC differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of VSMC differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of VSMC differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of vascular associated smooth muscle cell differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of vascular smooth muscle cell differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of VSMC differentiation" NARROW [GOC:TermGenie]
synonym: "negative regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "negative regulation of VSMC differentiation" EXACT [GOC:TermGenie]
is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation
is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation
relationship: negatively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation
created_by: rph
creation_date: 2016-03-21T11:15:03Z

[Term]
id: GO:1905065
name: positive regulation of vascular associated smooth muscle cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079]
synonym: "activation of vascular associated smooth muscle cell differentiation" NARROW [GOC:TermGenie]
synonym: "activation of vascular smooth muscle cell differentiation" NARROW [GOC:TermGenie]
synonym: "activation of VSMC differentiation" NARROW [GOC:TermGenie]
synonym: "positive regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "positive regulation of VSMC differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of VSMC differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of VSMC differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of VSMC differentiation" EXACT [GOC:TermGenie]
is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation
is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation
relationship: positively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation
created_by: rph
creation_date: 2016-03-21T11:15:13Z

[Term]
id: GO:1905069
name: allantois development
namespace: biological_process
def: "The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:17440924, PMID:21470579]
synonym: "allantoic bud development" RELATED [GOC:TermGenie]
is_a: GO:1903867 ! extraembryonic membrane development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0004340 ! allantois
relationship: results_in_development_of UBERON:0004340 ! allantois
created_by: cls
creation_date: 2016-03-21T15:18:21Z

[Term]
id: GO:1905126
name: regulation of axo-dendritic protein transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152]
synonym: "regulation of axonal protein transport" NARROW [GOC:TermGenie]
is_a: GO:0033157 ! regulation of intracellular protein transport
is_a: GO:0060632 ! regulation of microtubule-based movement
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0099640 ! axo-dendritic protein transport
relationship: regulates GO:0099640 ! axo-dendritic protein transport
created_by: sl
creation_date: 2016-04-11T20:38:31Z

[Term]
id: GO:1905127
name: negative regulation of axo-dendritic protein transport
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152]
synonym: "down regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie]
synonym: "down regulation of axonal protein transport" NARROW [GOC:TermGenie]
synonym: "down-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie]
synonym: "down-regulation of axonal protein transport" NARROW [GOC:TermGenie]
synonym: "downregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie]
synonym: "downregulation of axonal protein transport" NARROW [GOC:TermGenie]
synonym: "inhibition of axo-dendritic protein transport" NARROW [GOC:TermGenie]
synonym: "inhibition of axonal protein transport" NARROW [GOC:TermGenie]
synonym: "negative regulation of axonal protein transport" NARROW [GOC:TermGenie]
is_a: GO:0090317 ! negative regulation of intracellular protein transport
is_a: GO:1905126 ! regulation of axo-dendritic protein transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0099640 ! axo-dendritic protein transport
relationship: negatively_regulates GO:0099640 ! axo-dendritic protein transport
created_by: sl
creation_date: 2016-04-11T20:38:40Z

[Term]
id: GO:1905128
name: positive regulation of axo-dendritic protein transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152]
synonym: "activation of axo-dendritic protein transport" NARROW [GOC:TermGenie]
synonym: "activation of axonal protein transport" NARROW [GOC:TermGenie]
synonym: "positive regulation of axonal protein transport" NARROW [GOC:TermGenie]
synonym: "up regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie]
synonym: "up regulation of axonal protein transport" NARROW [GOC:TermGenie]
synonym: "up-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie]
synonym: "up-regulation of axonal protein transport" NARROW [GOC:TermGenie]
synonym: "upregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie]
synonym: "upregulation of axonal protein transport" NARROW [GOC:TermGenie]
is_a: GO:0090316 ! positive regulation of intracellular protein transport
is_a: GO:1905126 ! regulation of axo-dendritic protein transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0099640 ! axo-dendritic protein transport
relationship: positively_regulates GO:0099640 ! axo-dendritic protein transport
created_by: sl
creation_date: 2016-04-11T20:38:48Z

[Term]
id: GO:1905139
name: apical ectodermal ridge formation
namespace: biological_process
def: "The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts." [GO_REF:0000081, GOC:TermGenie, PMID:18359901, PMID:9323126, PMID:9596583]
synonym: "AER formation" RELATED [GOC:TermGenie]
synonym: "apical epidermal ridge formation" EXACT [GOC:TermGenie]
synonym: "crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis
intersection_of: results_in_formation_of_anatomical_entity UBERON:0004356 ! apical ectodermal ridge
relationship: part_of GO:0035107 ! appendage morphogenesis
relationship: results_in_formation_of_anatomical_entity UBERON:0004356 ! apical ectodermal ridge
created_by: dph
creation_date: 2016-04-13T11:46:40Z

[Term]
id: GO:1905140
name: regulation of apical ectodermal ridge formation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901]
synonym: "regulation of AER formation" RELATED [GOC:TermGenie]
synonym: "regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie]
synonym: "regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1905139 ! apical ectodermal ridge formation
relationship: regulates GO:1905139 ! apical ectodermal ridge formation
created_by: dph
creation_date: 2016-04-13T12:16:40Z

[Term]
id: GO:1905141
name: negative regulation of apical ectodermal ridge formation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901]
synonym: "down regulation of AER formation" RELATED [GOC:TermGenie]
synonym: "down regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie]
synonym: "down regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie]
synonym: "down regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
synonym: "down-regulation of AER formation" RELATED [GOC:TermGenie]
synonym: "down-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
synonym: "downregulation of AER formation" RELATED [GOC:TermGenie]
synonym: "downregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie]
synonym: "downregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie]
synonym: "downregulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
synonym: "inhibition of AER formation" RELATED [GOC:TermGenie]
synonym: "inhibition of apical ectodermal ridge formation" NARROW [GOC:TermGenie]
synonym: "inhibition of apical epidermal ridge formation" NARROW [GOC:TermGenie]
synonym: "inhibition of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
synonym: "negative regulation of AER formation" RELATED [GOC:TermGenie]
synonym: "negative regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1905140 ! regulation of apical ectodermal ridge formation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1905139 ! apical ectodermal ridge formation
relationship: negatively_regulates GO:1905139 ! apical ectodermal ridge formation
created_by: dph
creation_date: 2016-04-13T12:16:48Z

[Term]
id: GO:1905142
name: positive regulation of apical ectodermal ridge formation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901]
synonym: "activation of AER formation" RELATED [GOC:TermGenie]
synonym: "positive regulation of AER formation" RELATED [GOC:TermGenie]
synonym: "positive regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie]
synonym: "positive regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
synonym: "up regulation of AER formation" RELATED [GOC:TermGenie]
synonym: "up regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie]
synonym: "up regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie]
synonym: "up regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
synonym: "up-regulation of AER formation" RELATED [GOC:TermGenie]
synonym: "up-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
synonym: "upregulation of AER formation" RELATED [GOC:TermGenie]
synonym: "upregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie]
synonym: "upregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie]
synonym: "upregulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1905140 ! regulation of apical ectodermal ridge formation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1905139 ! apical ectodermal ridge formation
relationship: positively_regulates GO:1905139 ! apical ectodermal ridge formation
created_by: dph
creation_date: 2016-04-13T12:16:57Z

[Term]
id: GO:1905144
name: response to acetylcholine
namespace: biological_process
def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21238497]
is_a: GO:0010033 ! response to organic substance
is_a: GO:1901698 ! response to nitrogen compound
is_a: GO:1901700 ! response to oxygen-containing compound
intersection_of: GO:0050896 ! response to stimulus
intersection_of: has_primary_input CHEBI:15355 ! acetylcholine
relationship: has_primary_input CHEBI:15355 ! acetylcholine
created_by: dos
creation_date: 2016-04-14T08:54:49Z

[Term]
id: GO:1905147
name: regulation of smooth muscle hypertrophy
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164]
is_a: GO:0014743 ! regulation of muscle hypertrophy
is_a: GO:0043502 ! regulation of muscle adaptation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014895 ! smooth muscle hypertrophy
relationship: regulates GO:0014895 ! smooth muscle hypertrophy
created_by: bc
creation_date: 2016-04-15T12:47:07Z

[Term]
id: GO:1905148
name: negative regulation of smooth muscle hypertrophy
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164]
synonym: "down regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie]
synonym: "down-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie]
synonym: "downregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie]
synonym: "inhibition of smooth muscle hypertrophy" NARROW [GOC:TermGenie]
is_a: GO:0014741 ! negative regulation of muscle hypertrophy
is_a: GO:0014745 ! negative regulation of muscle adaptation
is_a: GO:1905147 ! regulation of smooth muscle hypertrophy
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014895 ! smooth muscle hypertrophy
relationship: negatively_regulates GO:0014895 ! smooth muscle hypertrophy
created_by: bc
creation_date: 2016-04-15T12:47:16Z

[Term]
id: GO:1905149
name: positive regulation of smooth muscle hypertrophy
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164]
synonym: "activation of smooth muscle hypertrophy" NARROW [GOC:TermGenie]
synonym: "up regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie]
synonym: "up-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie]
synonym: "upregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie]
is_a: GO:0014742 ! positive regulation of muscle hypertrophy
is_a: GO:0014744 ! positive regulation of muscle adaptation
is_a: GO:1905147 ! regulation of smooth muscle hypertrophy
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014895 ! smooth muscle hypertrophy
relationship: positively_regulates GO:0014895 ! smooth muscle hypertrophy
created_by: bc
creation_date: 2016-04-15T12:47:24Z

[Term]
id: GO:1905153
name: regulation of membrane invagination
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353]
is_a: GO:0051128 ! regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010324 ! membrane invagination
relationship: regulates GO:0010324 ! membrane invagination
created_by: bf
creation_date: 2016-04-18T15:43:54Z

[Term]
id: GO:1905154
name: negative regulation of membrane invagination
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:26589353]
synonym: "down regulation of membrane invagination" EXACT [GOC:TermGenie]
synonym: "down-regulation of membrane invagination" EXACT [GOC:TermGenie]
synonym: "downregulation of membrane invagination" EXACT [GOC:TermGenie]
synonym: "inhibition of membrane invagination" NARROW [GOC:TermGenie]
is_a: GO:0051129 ! negative regulation of cellular component organization
is_a: GO:1905153 ! regulation of membrane invagination
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010324 ! membrane invagination
relationship: negatively_regulates GO:0010324 ! membrane invagination
created_by: bf
creation_date: 2016-04-18T15:44:04Z

[Term]
id: GO:1905155
name: positive regulation of membrane invagination
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of membrane invagination." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie]
synonym: "activation of membrane invagination" NARROW [GOC:TermGenie]
synonym: "up regulation of membrane invagination" EXACT [GOC:TermGenie]
synonym: "up-regulation of membrane invagination" EXACT [GOC:TermGenie]
synonym: "upregulation of membrane invagination" EXACT [GOC:TermGenie]
is_a: GO:0051130 ! positive regulation of cellular component organization
is_a: GO:1905153 ! regulation of membrane invagination
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010324 ! membrane invagination
relationship: positively_regulates GO:0010324 ! membrane invagination
created_by: bf
creation_date: 2016-04-18T15:44:12Z

[Term]
id: GO:1905207
name: regulation of cardiocyte differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713]
synonym: "regulation of cardiac cell differentiation" EXACT [GOC:TermGenie]
synonym: "regulation of heart cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035051 ! cardiocyte differentiation
relationship: regulates GO:0035051 ! cardiocyte differentiation
created_by: bc
creation_date: 2016-06-02T07:20:01Z

[Term]
id: GO:1905208
name: negative regulation of cardiocyte differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713]
synonym: "down regulation of cardiac cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of cardiocyte differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of heart cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of heart cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiac cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiocyte differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of heart cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of cardiac cell differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of cardiocyte differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of heart cell differentiation" NARROW [GOC:TermGenie]
synonym: "negative regulation of cardiac cell differentiation" EXACT [GOC:TermGenie]
synonym: "negative regulation of heart cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1905207 ! regulation of cardiocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035051 ! cardiocyte differentiation
relationship: negatively_regulates GO:0035051 ! cardiocyte differentiation
created_by: bc
creation_date: 2016-06-02T07:20:09Z

[Term]
id: GO:1905209
name: positive regulation of cardiocyte differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713]
synonym: "activation of cardiac cell differentiation" NARROW [GOC:TermGenie]
synonym: "activation of cardiocyte differentiation" NARROW [GOC:TermGenie]
synonym: "activation of heart cell differentiation" NARROW [GOC:TermGenie]
synonym: "positive regulation of cardiac cell differentiation" EXACT [GOC:TermGenie]
synonym: "positive regulation of heart cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of cardiac cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of cardiocyte differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of heart cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of heart cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of cardiac cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of cardiocyte differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of heart cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1905207 ! regulation of cardiocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035051 ! cardiocyte differentiation
relationship: positively_regulates GO:0035051 ! cardiocyte differentiation
created_by: bc
creation_date: 2016-06-02T07:20:16Z

[Term]
id: GO:1905213
name: negative regulation of mitotic chromosome condensation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:23219725]
is_a: GO:0010948 ! negative regulation of cell cycle process
is_a: GO:1902340 ! negative regulation of chromosome condensation
is_a: GO:1903379 ! regulation of mitotic chromosome condensation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007076 ! mitotic chromosome condensation
relationship: negatively_regulates GO:0007076 ! mitotic chromosome condensation
created_by: vw
creation_date: 2016-06-03T08:41:08Z

[Term]
id: GO:1905223
name: epicardium morphogenesis
namespace: biological_process
def: "The developmental process by which an epicardium is generated and organized." [GO_REF:0000083, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461]
synonym: "heart epicardium morphogenesis" EXACT [GOC:TermGenie]
synonym: "pericardium visceral mesothelium morphogenesis" RELATED [GOC:TermGenie]
synonym: "visceral serous pericardium of heart morphogenesis" EXACT [GOC:TermGenie]
synonym: "visceral serous pericardium proper morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:0009653 ! anatomical structure morphogenesis
intersection_of: GO:0009653 ! anatomical structure morphogenesis
intersection_of: results_in_morphogenesis_of UBERON:0002348 ! epicardium
relationship: results_in_morphogenesis_of UBERON:0002348 ! epicardium
created_by: rl
creation_date: 2016-06-07T10:02:32Z

[Term]
id: GO:1905268
name: negative regulation of chromatin organization
namespace: biological_process
alt_id: GO:0045798
alt_id: GO:1903309
def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321]
synonym: "down regulation of chromatin assembly or disassembly" RELATED []
synonym: "down regulation of chromatin organisation" EXACT [GOC:TermGenie]
synonym: "down regulation of chromatin organization" EXACT [GOC:TermGenie]
synonym: "down regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie]
synonym: "down-regulation of chromatin assembly or disassembly" RELATED []
synonym: "down-regulation of chromatin organisation" EXACT [GOC:TermGenie]
synonym: "down-regulation of chromatin organization" EXACT [GOC:TermGenie]
synonym: "down-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie]
synonym: "downregulation of chromatin assembly or disassembly" RELATED []
synonym: "downregulation of chromatin organisation" EXACT [GOC:TermGenie]
synonym: "downregulation of chromatin organization" EXACT [GOC:TermGenie]
synonym: "downregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie]
synonym: "inhibition of chromatin assembly or disassembly" NARROW []
synonym: "inhibition of chromatin organisation" NARROW [GOC:TermGenie]
synonym: "inhibition of chromatin organization" NARROW [GOC:TermGenie]
synonym: "inhibition of establishment or maintenance of chromatin architecture" NARROW [GOC:TermGenie]
synonym: "negative regulation of chromatin assembly or disassembly" RELATED []
synonym: "negative regulation of chromatin assembly/disassembly" EXACT []
synonym: "negative regulation of chromatin modification" RELATED []
synonym: "negative regulation of chromatin organisation" EXACT [GOC:TermGenie]
synonym: "negative regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie]
is_a: GO:0051129 ! negative regulation of cellular component organization
is_a: GO:1902275 ! regulation of chromatin organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0006325 ! chromatin organization
relationship: negatively_regulates GO:0006325 ! chromatin organization
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22766" xsd:anyURI
created_by: pr
creation_date: 2016-06-15T20:14:47Z

[Term]
id: GO:1905269
name: positive regulation of chromatin organization
namespace: biological_process
alt_id: GO:0045799
alt_id: GO:1903310
def: "Any process that activates or increases the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321]
synonym: "activation of chromatin assembly or disassembly" NARROW []
synonym: "activation of chromatin organisation" NARROW [GOC:TermGenie]
synonym: "activation of chromatin organization" NARROW [GOC:TermGenie]
synonym: "activation of establishment or maintenance of chromatin architecture" NARROW [GOC:TermGenie]
synonym: "positive regulation of chromatin assembly or disassembly" RELATED []
synonym: "positive regulation of chromatin assembly/disassembly" RELATED []
synonym: "positive regulation of chromatin modification" RELATED []
synonym: "positive regulation of chromatin organisation" EXACT [GOC:TermGenie]
synonym: "positive regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie]
synonym: "stimulation of chromatin assembly or disassembly" NARROW []
synonym: "up regulation of chromatin assembly or disassembly" RELATED []
synonym: "up regulation of chromatin organisation" EXACT [GOC:TermGenie]
synonym: "up regulation of chromatin organization" EXACT [GOC:TermGenie]
synonym: "up regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie]
synonym: "up-regulation of chromatin assembly or disassembly" RELATED []
synonym: "up-regulation of chromatin organisation" EXACT [GOC:TermGenie]
synonym: "up-regulation of chromatin organization" EXACT [GOC:TermGenie]
synonym: "up-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie]
synonym: "upregulation of chromatin assembly or disassembly" EXACT []
synonym: "upregulation of chromatin organisation" EXACT [GOC:TermGenie]
synonym: "upregulation of chromatin organization" EXACT [GOC:TermGenie]
synonym: "upregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie]
is_a: GO:1902275 ! regulation of chromatin organization
is_a: GO:2001252 ! positive regulation of chromosome organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0006325 ! chromatin organization
relationship: positively_regulates GO:0006325 ! chromatin organization
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22766" xsd:anyURI
created_by: pr
creation_date: 2016-06-15T20:14:56Z

[Term]
id: GO:1905276
name: regulation of epithelial tube formation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997]
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).
is_a: GO:1905330 ! regulation of morphogenesis of an epithelium
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072175 ! epithelial tube formation
relationship: regulates GO:0072175 ! epithelial tube formation
created_by: bhm
creation_date: 2016-06-20T09:35:41Z

[Term]
id: GO:1905277
name: negative regulation of epithelial tube formation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997]
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).
synonym: "down regulation of epithelial tube formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of epithelial tube formation" EXACT [GOC:TermGenie]
synonym: "downregulation of epithelial tube formation" EXACT [GOC:TermGenie]
synonym: "inhibition of epithelial tube formation" NARROW [GOC:TermGenie]
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1905276 ! regulation of epithelial tube formation
is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072175 ! epithelial tube formation
relationship: negatively_regulates GO:0072175 ! epithelial tube formation
created_by: bhm
creation_date: 2016-06-20T09:35:49Z

[Term]
id: GO:1905278
name: positive regulation of epithelial tube formation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997]
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).
synonym: "activation of epithelial tube formation" NARROW [GOC:TermGenie]
synonym: "up regulation of epithelial tube formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of epithelial tube formation" EXACT [GOC:TermGenie]
synonym: "upregulation of epithelial tube formation" EXACT [GOC:TermGenie]
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1905276 ! regulation of epithelial tube formation
is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072175 ! epithelial tube formation
relationship: positively_regulates GO:0072175 ! epithelial tube formation
created_by: bhm
creation_date: 2016-06-20T09:35:57Z

[Term]
id: GO:1905288
name: vascular associated smooth muscle cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a vascular associated smooth muscle cell." [GO_REF:0000085, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107]
synonym: "vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "VSMC apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0034390 ! smooth muscle cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0000359 ! vascular associated smooth muscle cell
relationship: occurs_in CL:0000359 ! vascular associated smooth muscle cell
created_by: rph
creation_date: 2016-06-23T13:24:20Z

[Term]
id: GO:1905292
name: regulation of neural crest cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157]
is_a: GO:2000736 ! regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0014033 ! neural crest cell differentiation
relationship: regulates GO:0014033 ! neural crest cell differentiation
created_by: rl
creation_date: 2016-06-28T15:02:01Z

[Term]
id: GO:1905293
name: negative regulation of neural crest cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157]
synonym: "down regulation of neural crest cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of neural crest cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of neural crest cell differentiation" NARROW [GOC:TermGenie]
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1905292 ! regulation of neural crest cell differentiation
is_a: GO:2000737 ! negative regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0014033 ! neural crest cell differentiation
relationship: negatively_regulates GO:0014033 ! neural crest cell differentiation
created_by: rl
creation_date: 2016-06-28T15:02:09Z

[Term]
id: GO:1905294
name: positive regulation of neural crest cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157]
synonym: "activation of neural crest cell differentiation" NARROW [GOC:TermGenie]
synonym: "up regulation of neural crest cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of neural crest cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1905292 ! regulation of neural crest cell differentiation
is_a: GO:2000738 ! positive regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0014033 ! neural crest cell differentiation
relationship: positively_regulates GO:0014033 ! neural crest cell differentiation
created_by: rl
creation_date: 2016-06-28T15:02:16Z

[Term]
id: GO:1905298
name: regulation of intestinal epithelial cell development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268]
is_a: GO:0030856 ! regulation of epithelial cell differentiation
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060576 ! intestinal epithelial cell development
relationship: regulates GO:0060576 ! intestinal epithelial cell development
created_by: rph
creation_date: 2016-06-30T11:40:47Z

[Term]
id: GO:1905299
name: negative regulation of intestinal epithelial cell development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268]
synonym: "down regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie]
synonym: "down-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie]
synonym: "downregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie]
synonym: "inhibition of intestinal epithelial cell development" NARROW [GOC:TermGenie]
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0030857 ! negative regulation of epithelial cell differentiation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1905298 ! regulation of intestinal epithelial cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060576 ! intestinal epithelial cell development
relationship: negatively_regulates GO:0060576 ! intestinal epithelial cell development
created_by: rph
creation_date: 2016-06-30T11:40:55Z

[Term]
id: GO:1905300
name: positive regulation of intestinal epithelial cell development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268]
synonym: "activation of intestinal epithelial cell development" NARROW [GOC:TermGenie]
synonym: "up regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie]
synonym: "up-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie]
synonym: "upregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie]
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1905298 ! regulation of intestinal epithelial cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060576 ! intestinal epithelial cell development
relationship: positively_regulates GO:0060576 ! intestinal epithelial cell development
created_by: rph
creation_date: 2016-06-30T11:41:02Z

[Term]
id: GO:1905304
name: regulation of cardiac myofibril assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019]
synonym: "regulation of cardiac myofibril development" EXACT [GOC:TermGenie]
synonym: "regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie]
synonym: "regulation of heart myofibril assembly" RELATED [GOC:TermGenie]
is_a: GO:0060284 ! regulation of cell development
is_a: GO:0110020 ! regulation of actomyosin structure organization
is_a: GO:1902115 ! regulation of organelle assembly
is_a: GO:1902903 ! regulation of supramolecular fiber organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0055003 ! cardiac myofibril assembly
relationship: regulates GO:0055003 ! cardiac myofibril assembly
created_by: rl
creation_date: 2016-07-06T10:01:49Z

[Term]
id: GO:1905305
name: negative regulation of cardiac myofibril assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019]
synonym: "down regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie]
synonym: "down regulation of cardiac myofibril development" EXACT [GOC:TermGenie]
synonym: "down regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie]
synonym: "down regulation of heart myofibril assembly" RELATED [GOC:TermGenie]
synonym: "down-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiac myofibril development" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of heart myofibril assembly" RELATED [GOC:TermGenie]
synonym: "downregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiac myofibril development" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of heart myofibril assembly" RELATED [GOC:TermGenie]
synonym: "inhibition of cardiac myofibril assembly" NARROW [GOC:TermGenie]
synonym: "inhibition of cardiac myofibril development" NARROW [GOC:TermGenie]
synonym: "inhibition of cardiac myofibril morphogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of heart myofibril assembly" RELATED [GOC:TermGenie]
synonym: "negative regulation of cardiac myofibril development" EXACT [GOC:TermGenie]
synonym: "negative regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of heart myofibril assembly" RELATED [GOC:TermGenie]
is_a: GO:0051494 ! negative regulation of cytoskeleton organization
is_a: GO:1902116 ! negative regulation of organelle assembly
is_a: GO:1902904 ! negative regulation of supramolecular fiber organization
is_a: GO:1905304 ! regulation of cardiac myofibril assembly
is_a: GO:2000726 ! negative regulation of cardiac muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0055003 ! cardiac myofibril assembly
relationship: negatively_regulates GO:0055003 ! cardiac myofibril assembly
created_by: rl
creation_date: 2016-07-06T10:01:58Z

[Term]
id: GO:1905306
name: positive regulation of cardiac myofibril assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019]
synonym: "activation of cardiac myofibril assembly" NARROW [GOC:TermGenie]
synonym: "activation of cardiac myofibril development" NARROW [GOC:TermGenie]
synonym: "activation of cardiac myofibril morphogenesis" NARROW [GOC:TermGenie]
synonym: "activation of heart myofibril assembly" RELATED [GOC:TermGenie]
synonym: "positive regulation of cardiac myofibril development" EXACT [GOC:TermGenie]
synonym: "positive regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of heart myofibril assembly" RELATED [GOC:TermGenie]
synonym: "up regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie]
synonym: "up regulation of cardiac myofibril development" EXACT [GOC:TermGenie]
synonym: "up regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of heart myofibril assembly" RELATED [GOC:TermGenie]
synonym: "up-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of cardiac myofibril development" EXACT [GOC:TermGenie]
synonym: "up-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of heart myofibril assembly" RELATED [GOC:TermGenie]
synonym: "upregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of cardiac myofibril development" EXACT [GOC:TermGenie]
synonym: "upregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of heart myofibril assembly" RELATED [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051495 ! positive regulation of cytoskeleton organization
is_a: GO:1902117 ! positive regulation of organelle assembly
is_a: GO:1902905 ! positive regulation of supramolecular fiber organization
is_a: GO:1905304 ! regulation of cardiac myofibril assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0055003 ! cardiac myofibril assembly
relationship: positively_regulates GO:0055003 ! cardiac myofibril assembly
created_by: rl
creation_date: 2016-07-06T10:02:07Z

[Term]
id: GO:1905310
name: regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518]
is_a: GO:0030334 ! regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis
relationship: regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis
created_by: rl
creation_date: 2016-07-11T17:34:26Z

[Term]
id: GO:1905311
name: negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518]
synonym: "down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
is_a: GO:0030336 ! negative regulation of cell migration
is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis
relationship: negatively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis
created_by: rl
creation_date: 2016-07-11T17:34:35Z

[Term]
id: GO:1905312
name: positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518]
synonym: "activation of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:0030335 ! positive regulation of cell migration
is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis
relationship: positively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis
created_by: rl
creation_date: 2016-07-11T17:34:43Z

[Term]
id: GO:1905315
name: cell proliferation involved in endocardial cushion morphogenesis
namespace: biological_process
def: "Any cell proliferation that is involved in endocardial cushion morphogenesis." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20652948]
is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis
relationship: part_of GO:0003203 ! endocardial cushion morphogenesis
created_by: rl
creation_date: 2016-07-12T13:56:36Z

[Term]
id: GO:1905319
name: mesenchymal stem cell migration
namespace: biological_process
def: "The orderly movement of a mesenchymal stem cell from one site to another." [GO_REF:0000091, GOC:TermGenie, PMID:24924806, PMID:25181476]
is_a: GO:0016477 ! cell migration
intersection_of: GO:0016477 ! cell migration
intersection_of: results_in_movement_of CL:0000134 ! mesenchymal stem cell
relationship: results_in_movement_of CL:0000134 ! mesenchymal stem cell
created_by: sl
creation_date: 2016-07-14T17:13:02Z

[Term]
id: GO:1905320
name: regulation of mesenchymal stem cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297]
is_a: GO:0030334 ! regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1905319 ! mesenchymal stem cell migration
relationship: regulates GO:1905319 ! mesenchymal stem cell migration
created_by: sl
creation_date: 2016-07-15T22:19:14Z

[Term]
id: GO:1905321
name: negative regulation of mesenchymal stem cell migration
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297]
synonym: "down regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie]
synonym: "down-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie]
synonym: "downregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie]
synonym: "inhibition of mesenchymal stem cell migration" NARROW [GOC:TermGenie]
is_a: GO:0030336 ! negative regulation of cell migration
is_a: GO:1905320 ! regulation of mesenchymal stem cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1905319 ! mesenchymal stem cell migration
relationship: negatively_regulates GO:1905319 ! mesenchymal stem cell migration
created_by: sl
creation_date: 2016-07-15T22:19:22Z

[Term]
id: GO:1905322
name: positive regulation of mesenchymal stem cell migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297]
synonym: "activation of mesenchymal stem cell migration" NARROW [GOC:TermGenie]
synonym: "up regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie]
synonym: "up-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie]
synonym: "upregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie]
is_a: GO:0030335 ! positive regulation of cell migration
is_a: GO:1905320 ! regulation of mesenchymal stem cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1905319 ! mesenchymal stem cell migration
relationship: positively_regulates GO:1905319 ! mesenchymal stem cell migration
created_by: sl
creation_date: 2016-07-15T22:19:29Z

[Term]
id: GO:1905330
name: regulation of morphogenesis of an epithelium
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997]
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).
synonym: "regulation of epithelium morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002009 ! morphogenesis of an epithelium
relationship: regulates GO:0002009 ! morphogenesis of an epithelium
created_by: bhm
creation_date: 2016-07-22T07:13:49Z

[Term]
id: GO:1905331
name: negative regulation of morphogenesis of an epithelium
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997]
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).
synonym: "down regulation of epithelium morphogenesis" EXACT [GOC:TermGenie]
synonym: "down regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie]
synonym: "down-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie]
synonym: "downregulation of epithelium morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie]
synonym: "inhibition of epithelium morphogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of morphogenesis of an epithelium" NARROW [GOC:TermGenie]
synonym: "negative regulation of epithelium morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:1905330 ! regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002009 ! morphogenesis of an epithelium
relationship: negatively_regulates GO:0002009 ! morphogenesis of an epithelium
created_by: bhm
creation_date: 2016-07-22T07:13:57Z

[Term]
id: GO:1905332
name: positive regulation of morphogenesis of an epithelium
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997]
comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).
synonym: "activation of epithelium morphogenesis" NARROW [GOC:TermGenie]
synonym: "activation of morphogenesis of an epithelium" NARROW [GOC:TermGenie]
synonym: "positive regulation of epithelium morphogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of epithelium morphogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie]
synonym: "up-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie]
synonym: "upregulation of epithelium morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:1905330 ! regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002009 ! morphogenesis of an epithelium
relationship: positively_regulates GO:0002009 ! morphogenesis of an epithelium
created_by: bhm
creation_date: 2016-07-22T07:14:05Z

[Term]
id: GO:1905349
name: ciliary transition zone assembly
namespace: biological_process
def: "The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone." [GO_REF:0000079, GOC:cilia, GOC:TermGenie, PMID:21725307, PMID:23644468, PMID:24448408, PMID:26595381, PMID:26982032]
synonym: "cilial transition zone assembly" EXACT [GOC:TermGenie]
synonym: "cilial transition zone formation" EXACT [GOC:TermGenie]
synonym: "ciliary transition zone formation" EXACT [GOC:TermGenie]
synonym: "cilium transition zone assembly" EXACT [GOC:TermGenie]
synonym: "cilium transition zone formation" EXACT [GOC:TermGenie]
is_a: GO:0022607 ! cellular component assembly
intersection_of: GO:0022607 ! cellular component assembly
intersection_of: results_in_assembly_of GO:0035869 ! ciliary transition zone
relationship: part_of GO:0060271 ! cilium assembly
relationship: results_in_assembly_of GO:0035869 ! ciliary transition zone
created_by: pr
creation_date: 2016-08-04T14:49:43Z

[Term]
id: GO:1905383
name: protein localization to presynapse
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a presynapse." [GO_REF:0000087, GOC:TermGenie, PMID:24449494]
synonym: "protein localisation in presynapse" EXACT [GOC:TermGenie]
synonym: "protein localisation to presynapse" EXACT [GOC:TermGenie]
synonym: "protein localization in presynapse" EXACT [GOC:TermGenie]
synonym: "recruitment of presynaptic proteins" EXACT [PMID:24449494]
is_a: GO:0035418 ! protein localization to synapse
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0098793 ! presynapse
relationship: has_target_end_location GO:0098793 ! presynapse
created_by: dos
creation_date: 2016-08-18T14:42:59Z

[Term]
id: GO:1905384
name: regulation of protein localization to presynapse
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494]
synonym: "regulation of protein localisation in presynapse" EXACT [GOC:TermGenie]
synonym: "regulation of protein localisation to presynapse" EXACT [GOC:TermGenie]
synonym: "regulation of protein localization in presynapse" EXACT [GOC:TermGenie]
synonym: "regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie]
is_a: GO:1902473 ! regulation of protein localization to synapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1905383 ! protein localization to presynapse
relationship: regulates GO:1905383 ! protein localization to presynapse
created_by: dos
creation_date: 2016-08-18T14:56:00Z

[Term]
id: GO:1905385
name: negative regulation of protein localization to presynapse
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494]
synonym: "down regulation of protein localisation in presynapse" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localisation to presynapse" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization in presynapse" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization to presynapse" EXACT [GOC:TermGenie]
synonym: "down regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization in presynapse" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to presynapse" EXACT [GOC:TermGenie]
synonym: "down-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation in presynapse" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation to presynapse" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization in presynapse" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to presynapse" EXACT [GOC:TermGenie]
synonym: "downregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie]
synonym: "inhibition of protein localisation in presynapse" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localisation to presynapse" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization in presynapse" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization to presynapse" NARROW [GOC:TermGenie]
synonym: "inhibition of recruitment of presynaptic proteins" NARROW [GOC:TermGenie]
synonym: "negative regulation of protein localisation in presynapse" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localisation to presynapse" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localization in presynapse" EXACT [GOC:TermGenie]
synonym: "negative regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie]
is_a: GO:1903828 ! negative regulation of protein localization
is_a: GO:1905384 ! regulation of protein localization to presynapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1905383 ! protein localization to presynapse
relationship: negatively_regulates GO:1905383 ! protein localization to presynapse
created_by: dos
creation_date: 2016-08-18T14:56:08Z

[Term]
id: GO:1905386
name: positive regulation of protein localization to presynapse
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494]
synonym: "activation of protein localisation in presynapse" NARROW [GOC:TermGenie]
synonym: "activation of protein localisation to presynapse" NARROW [GOC:TermGenie]
synonym: "activation of protein localization in presynapse" NARROW [GOC:TermGenie]
synonym: "activation of protein localization to presynapse" NARROW [GOC:TermGenie]
synonym: "activation of recruitment of presynaptic proteins" NARROW [GOC:TermGenie]
synonym: "positive regulation of protein localisation in presynapse" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localisation to presynapse" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localization in presynapse" EXACT [GOC:TermGenie]
synonym: "positive regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation in presynapse" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation to presynapse" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization in presynapse" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization to presynapse" EXACT [GOC:TermGenie]
synonym: "up regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization in presynapse" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to presynapse" EXACT [GOC:TermGenie]
synonym: "up-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation in presynapse" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation to presynapse" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization in presynapse" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to presynapse" EXACT [GOC:TermGenie]
synonym: "upregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie]
is_a: GO:1902474 ! positive regulation of protein localization to synapse
is_a: GO:1905384 ! regulation of protein localization to presynapse
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1905383 ! protein localization to presynapse
relationship: positively_regulates GO:1905383 ! protein localization to presynapse
created_by: dos
creation_date: 2016-08-18T14:56:21Z

[Term]
id: GO:1905432
name: regulation of retrograde trans-synaptic signaling by neuropeptide
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629]
synonym: "regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf]
is_a: GO:0099177 ! regulation of trans-synaptic signaling
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide
relationship: regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide
created_by: bf
creation_date: 2016-09-14T10:56:47Z

[Term]
id: GO:1905433
name: negative regulation of retrograde trans-synaptic signaling by neuropeptide
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629]
synonym: "down regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie]
synonym: "down-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie]
synonym: "downregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie]
synonym: "inhibition of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf]
synonym: "inhibition of retrograde trans-synaptic signaling by neuropeptide" NARROW [GOC:TermGenie]
synonym: "negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf]
is_a: GO:0010648 ! negative regulation of cell communication
is_a: GO:0023057 ! negative regulation of signaling
is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide
relationship: negatively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide
created_by: bf
creation_date: 2016-09-14T10:56:55Z

[Term]
id: GO:1905434
name: positive regulation of retrograde trans-synaptic signaling by neuropeptide
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629]
synonym: "activation of retrograde trans-synaptic signaling by neuropeptide" NARROW [GOC:TermGenie]
synonym: "positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf]
synonym: "up regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie]
synonym: "up-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie]
synonym: "upregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie]
is_a: GO:0010647 ! positive regulation of cell communication
is_a: GO:0023056 ! positive regulation of signaling
is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide
relationship: positively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide
created_by: bf
creation_date: 2016-09-14T10:57:02Z

[Term]
id: GO:1905453
name: regulation of myeloid progenitor cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503]
is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002318 ! myeloid progenitor cell differentiation
relationship: regulates GO:0002318 ! myeloid progenitor cell differentiation
created_by: rz
creation_date: 2016-09-16T12:32:18Z

[Term]
id: GO:1905454
name: negative regulation of myeloid progenitor cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503]
synonym: "down regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of myeloid progenitor cell differentiation" NARROW [GOC:TermGenie]
is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation
is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002318 ! myeloid progenitor cell differentiation
relationship: negatively_regulates GO:0002318 ! myeloid progenitor cell differentiation
created_by: rz
creation_date: 2016-09-16T12:32:26Z

[Term]
id: GO:1905455
name: positive regulation of myeloid progenitor cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503]
synonym: "activation of myeloid progenitor cell differentiation" NARROW [GOC:TermGenie]
synonym: "up regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation
is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002318 ! myeloid progenitor cell differentiation
relationship: positively_regulates GO:0002318 ! myeloid progenitor cell differentiation
created_by: rz
creation_date: 2016-09-16T12:32:33Z

[Term]
id: GO:1905456
name: regulation of lymphoid progenitor cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503]
is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002320 ! lymphoid progenitor cell differentiation
relationship: regulates GO:0002320 ! lymphoid progenitor cell differentiation
created_by: rz
creation_date: 2016-09-16T12:32:40Z

[Term]
id: GO:1905457
name: negative regulation of lymphoid progenitor cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503]
synonym: "down regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of lymphoid progenitor cell differentiation" NARROW [GOC:TermGenie]
is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation
is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002320 ! lymphoid progenitor cell differentiation
relationship: negatively_regulates GO:0002320 ! lymphoid progenitor cell differentiation
created_by: rz
creation_date: 2016-09-16T12:32:48Z

[Term]
id: GO:1905458
name: positive regulation of lymphoid progenitor cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503]
synonym: "activation of lymphoid progenitor cell differentiation" NARROW [GOC:TermGenie]
synonym: "up regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation
is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002320 ! lymphoid progenitor cell differentiation
relationship: positively_regulates GO:0002320 ! lymphoid progenitor cell differentiation
created_by: rz
creation_date: 2016-09-16T12:32:55Z

[Term]
id: GO:1905459
name: regulation of vascular associated smooth muscle cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107]
synonym: "regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "regulation of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "regulation of VSMC apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process
relationship: regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process
created_by: rph
creation_date: 2016-09-19T11:33:54Z

[Term]
id: GO:1905460
name: negative regulation of vascular associated smooth muscle cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107]
synonym: "down regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down regulation of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "down regulation of VSMC apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "down-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "downregulation of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "downregulation of VSMC apoptotic process" EXACT [GOC:TermGenie]
synonym: "inhibition of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of vascular associated smooth muscle cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "inhibition of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of vascular smooth muscle cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "inhibition of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "inhibition of VSMC apoptotic process" NARROW [GOC:TermGenie]
synonym: "negative regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "negative regulation of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "negative regulation of VSMC apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0034392 ! negative regulation of smooth muscle cell apoptotic process
is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process
relationship: negatively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process
created_by: rph
creation_date: 2016-09-19T11:34:03Z

[Term]
id: GO:1905461
name: positive regulation of vascular associated smooth muscle cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107]
synonym: "activation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of vascular associated smooth muscle cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "activation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of vascular smooth muscle cell apoptotic process" NARROW [GOC:TermGenie]
synonym: "activation of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "activation of VSMC apoptotic process" NARROW [GOC:TermGenie]
synonym: "positive regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "positive regulation of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "positive regulation of VSMC apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up regulation of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "up regulation of VSMC apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "up-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie]
synonym: "upregulation of VSMC apoptosis" NARROW [GOC:TermGenie]
synonym: "upregulation of VSMC apoptotic process" EXACT [GOC:TermGenie]
is_a: GO:0034393 ! positive regulation of smooth muscle cell apoptotic process
is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process
relationship: positively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process
created_by: rph
creation_date: 2016-09-19T11:34:10Z

[Term]
id: GO:1905475
name: regulation of protein localization to membrane
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690]
synonym: "regulation of protein localisation in membrane" EXACT [GOC:TermGenie]
synonym: "regulation of protein localization in membrane" EXACT [GOC:TermGenie]
is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072657 ! protein localization to membrane
relationship: regulates GO:0072657 ! protein localization to membrane
created_by: bc
creation_date: 2016-09-21T16:20:03Z

[Term]
id: GO:1905476
name: negative regulation of protein localization to membrane
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690]
synonym: "down regulation of protein localisation in membrane" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization in membrane" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization to membrane" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation in membrane" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization in membrane" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to membrane" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation in membrane" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization in membrane" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to membrane" EXACT [GOC:TermGenie]
synonym: "inhibition of protein localisation in membrane" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization in membrane" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization to membrane" NARROW [GOC:TermGenie]
synonym: "negative regulation of protein localisation in membrane" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localization in membrane" EXACT [GOC:TermGenie]
is_a: GO:1903828 ! negative regulation of protein localization
is_a: GO:1905475 ! regulation of protein localization to membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072657 ! protein localization to membrane
relationship: negatively_regulates GO:0072657 ! protein localization to membrane
created_by: bc
creation_date: 2016-09-21T16:20:10Z

[Term]
id: GO:1905477
name: positive regulation of protein localization to membrane
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690]
synonym: "activation of protein localisation in membrane" NARROW [GOC:TermGenie]
synonym: "activation of protein localization in membrane" NARROW [GOC:TermGenie]
synonym: "activation of protein localization to membrane" NARROW [GOC:TermGenie]
synonym: "positive regulation of protein localisation in membrane" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localization in membrane" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation in membrane" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization in membrane" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization to membrane" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation in membrane" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization in membrane" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to membrane" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation in membrane" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization in membrane" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to membrane" EXACT [GOC:TermGenie]
is_a: GO:1903829 ! positive regulation of protein localization
is_a: GO:1905475 ! regulation of protein localization to membrane
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072657 ! protein localization to membrane
relationship: positively_regulates GO:0072657 ! protein localization to membrane
created_by: bc
creation_date: 2016-09-21T16:20:18Z

[Term]
id: GO:1905483
name: regulation of motor neuron migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839]
is_a: GO:2001222 ! regulation of neuron migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097475 ! motor neuron migration
relationship: regulates GO:0097475 ! motor neuron migration
created_by: hbye
creation_date: 2016-09-23T12:49:54Z

[Term]
id: GO:1905484
name: negative regulation of motor neuron migration
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839]
synonym: "down regulation of motor neuron migration" EXACT [GOC:TermGenie]
synonym: "down-regulation of motor neuron migration" EXACT [GOC:TermGenie]
synonym: "downregulation of motor neuron migration" EXACT [GOC:TermGenie]
synonym: "inhibition of motor neuron migration" NARROW [GOC:TermGenie]
is_a: GO:1905483 ! regulation of motor neuron migration
is_a: GO:2001223 ! negative regulation of neuron migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097475 ! motor neuron migration
relationship: negatively_regulates GO:0097475 ! motor neuron migration
created_by: hbye
creation_date: 2016-09-23T12:50:11Z

[Term]
id: GO:1905485
name: positive regulation of motor neuron migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839]
synonym: "activation of motor neuron migration" NARROW [GOC:TermGenie]
synonym: "up regulation of motor neuron migration" EXACT [GOC:TermGenie]
synonym: "up-regulation of motor neuron migration" EXACT [GOC:TermGenie]
synonym: "upregulation of motor neuron migration" EXACT [GOC:TermGenie]
is_a: GO:1905483 ! regulation of motor neuron migration
is_a: GO:2001224 ! positive regulation of neuron migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097475 ! motor neuron migration
relationship: positively_regulates GO:0097475 ! motor neuron migration
created_by: hbye
creation_date: 2016-09-23T12:50:19Z

[Term]
id: GO:1905492
name: positive regulation of branching morphogenesis of a nerve
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve." [GO_REF:0000058, GOC:TermGenie, PMID:16516839]
synonym: "activation of branching morphogenesis of a nerve" NARROW [GOC:TermGenie]
synonym: "up regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie]
synonym: "up-regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie]
synonym: "upregulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048755 ! branching morphogenesis of a nerve
relationship: positively_regulates GO:0048755 ! branching morphogenesis of a nerve
created_by: hbye
creation_date: 2016-09-23T14:11:52Z

[Term]
id: GO:1905503
name: regulation of motile cilium assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941]
synonym: "regulation of motile primary cilia assembly" RELATED [GOC:TermGenie]
synonym: "regulation of motile primary cilia formation" RELATED [GOC:TermGenie]
synonym: "regulation of motile primary cilium assembly" RELATED []
synonym: "regulation of motile primary cilium formation" RELATED [GOC:TermGenie]
synonym: "regulation of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "regulation of nodal cilium formation" RELATED [GOC:TermGenie]
is_a: GO:1902017 ! regulation of cilium assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0044458 ! motile cilium assembly
relationship: regulates GO:0044458 ! motile cilium assembly
created_by: krc
creation_date: 2016-09-27T18:27:47Z

[Term]
id: GO:1905504
name: negative regulation of motile cilium assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941]
synonym: "down regulation of motile primary cilia assembly" RELATED [GOC:TermGenie]
synonym: "down regulation of motile primary cilia formation" RELATED [GOC:TermGenie]
synonym: "down regulation of motile primary cilium assembly" RELATED [GOC:TermGenie]
synonym: "down regulation of motile primary cilium formation" RELATED [GOC:TermGenie]
synonym: "down regulation of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "down regulation of nodal cilium formation" RELATED [GOC:TermGenie]
synonym: "down-regulation of motile primary cilia assembly" RELATED [GOC:TermGenie]
synonym: "down-regulation of motile primary cilia formation" RELATED [GOC:TermGenie]
synonym: "down-regulation of motile primary cilium assembly" RELATED [GOC:TermGenie]
synonym: "down-regulation of motile primary cilium formation" RELATED [GOC:TermGenie]
synonym: "down-regulation of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "down-regulation of nodal cilium formation" RELATED [GOC:TermGenie]
synonym: "downregulation of motile primary cilia assembly" RELATED [GOC:TermGenie]
synonym: "downregulation of motile primary cilia formation" RELATED [GOC:TermGenie]
synonym: "downregulation of motile primary cilium assembly" RELATED [GOC:TermGenie]
synonym: "downregulation of motile primary cilium formation" RELATED [GOC:TermGenie]
synonym: "downregulation of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "downregulation of nodal cilium formation" RELATED [GOC:TermGenie]
synonym: "inhibition of motile primary cilia assembly" NARROW [GOC:TermGenie]
synonym: "inhibition of motile primary cilia formation" NARROW [GOC:TermGenie]
synonym: "inhibition of motile primary cilium assembly" NARROW [GOC:TermGenie]
synonym: "inhibition of motile primary cilium formation" NARROW [GOC:TermGenie]
synonym: "inhibition of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "inhibition of nodal cilium formation" RELATED [GOC:TermGenie]
synonym: "negative regulation of motile primary cilia assembly" RELATED [GOC:TermGenie]
synonym: "negative regulation of motile primary cilia formation" RELATED [GOC:TermGenie]
synonym: "negative regulation of motile primary cilium assembly" RELATED []
synonym: "negative regulation of motile primary cilium formation" RELATED [GOC:TermGenie]
synonym: "negative regulation of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "negative regulation of nodal cilium formation" RELATED [GOC:TermGenie]
is_a: GO:1902018 ! negative regulation of cilium assembly
is_a: GO:1905503 ! regulation of motile cilium assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0044458 ! motile cilium assembly
relationship: negatively_regulates GO:0044458 ! motile cilium assembly
created_by: krc
creation_date: 2016-09-27T18:27:55Z

[Term]
id: GO:1905505
name: positive regulation of motile cilium assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941]
synonym: "activation of motile primary cilia assembly" NARROW [GOC:TermGenie]
synonym: "activation of motile primary cilia formation" NARROW [GOC:TermGenie]
synonym: "activation of motile primary cilium assembly" NARROW [GOC:TermGenie]
synonym: "activation of motile primary cilium formation" NARROW [GOC:TermGenie]
synonym: "activation of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "activation of nodal cilium formation" RELATED [GOC:TermGenie]
synonym: "positive regulation of motile primary cilia assembly" RELATED [GOC:TermGenie]
synonym: "positive regulation of motile primary cilia formation" RELATED [GOC:TermGenie]
synonym: "positive regulation of motile primary cilium assembly" RELATED []
synonym: "positive regulation of motile primary cilium formation" RELATED [GOC:TermGenie]
synonym: "positive regulation of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "positive regulation of nodal cilium formation" RELATED [GOC:TermGenie]
synonym: "up regulation of motile primary cilia assembly" RELATED [GOC:TermGenie]
synonym: "up regulation of motile primary cilia formation" RELATED [GOC:TermGenie]
synonym: "up regulation of motile primary cilium assembly" RELATED [GOC:TermGenie]
synonym: "up regulation of motile primary cilium formation" RELATED [GOC:TermGenie]
synonym: "up regulation of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "up regulation of nodal cilium formation" RELATED [GOC:TermGenie]
synonym: "up-regulation of motile primary cilia assembly" RELATED [GOC:TermGenie]
synonym: "up-regulation of motile primary cilia formation" RELATED [GOC:TermGenie]
synonym: "up-regulation of motile primary cilium assembly" RELATED [GOC:TermGenie]
synonym: "up-regulation of motile primary cilium formation" RELATED [GOC:TermGenie]
synonym: "up-regulation of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "up-regulation of nodal cilium formation" RELATED [GOC:TermGenie]
synonym: "upregulation of motile primary cilia assembly" RELATED [GOC:TermGenie]
synonym: "upregulation of motile primary cilia formation" RELATED [GOC:TermGenie]
synonym: "upregulation of motile primary cilium assembly" RELATED [GOC:TermGenie]
synonym: "upregulation of motile primary cilium formation" RELATED [GOC:TermGenie]
synonym: "upregulation of nodal cilium assembly" RELATED [GOC:TermGenie]
synonym: "upregulation of nodal cilium formation" RELATED [GOC:TermGenie]
is_a: GO:0045724 ! positive regulation of cilium assembly
is_a: GO:1905503 ! regulation of motile cilium assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0044458 ! motile cilium assembly
relationship: positively_regulates GO:0044458 ! motile cilium assembly
created_by: krc
creation_date: 2016-09-27T18:28:03Z

[Term]
id: GO:1905516
name: positive regulation of fertilization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of fertilization." [GO_REF:0000058, GOC:hbye, GOC:TermGenie, PMID:27564576]
synonym: "activation of fertilization" NARROW [GOC:TermGenie]
synonym: "activation of syngamy" NARROW [GOC:TermGenie]
synonym: "positive regulation of syngamy" EXACT [GOC:TermGenie]
synonym: "up regulation of fertilization" EXACT [GOC:TermGenie]
synonym: "up regulation of syngamy" EXACT [GOC:TermGenie]
synonym: "up-regulation of fertilization" EXACT [GOC:TermGenie]
synonym: "up-regulation of syngamy" EXACT [GOC:TermGenie]
synonym: "upregulation of fertilization" EXACT [GOC:TermGenie]
synonym: "upregulation of syngamy" EXACT [GOC:TermGenie]
is_a: GO:0080154 ! regulation of fertilization
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0009566 ! fertilization
relationship: positively_regulates GO:0009566 ! fertilization
created_by: pr
creation_date: 2016-09-30T14:32:32Z

[Term]
id: GO:1905553
name: regulation of blood vessel branching
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774]
synonym: "regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:0045765 ! regulation of angiogenesis
is_a: GO:0060688 ! regulation of morphogenesis of a branching structure
is_a: GO:1905330 ! regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001569 ! branching involved in blood vessel morphogenesis
relationship: regulates GO:0001569 ! branching involved in blood vessel morphogenesis
created_by: nc
creation_date: 2016-10-12T14:19:33Z

[Term]
id: GO:1905554
name: negative regulation of vessel branching
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774]
synonym: "down regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie]
synonym: "down regulation of patterning of blood vessels" EXACT [GOC:TermGenie]
synonym: "down-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of patterning of blood vessels" EXACT [GOC:TermGenie]
synonym: "downregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of patterning of blood vessels" EXACT [GOC:TermGenie]
synonym: "inhibition of branching involved in blood vessel morphogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of patterning of blood vessels" NARROW [GOC:TermGenie]
synonym: "negative regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:0016525 ! negative regulation of angiogenesis
is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium
is_a: GO:1905553 ! regulation of blood vessel branching
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis
relationship: negatively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis
created_by: nc
creation_date: 2016-10-12T14:19:41Z

[Term]
id: GO:1905555
name: positive regulation of blood vessel branching
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774]
synonym: "activation of branching involved in blood vessel morphogenesis" NARROW [GOC:TermGenie]
synonym: "activation of patterning of blood vessels" NARROW [GOC:TermGenie]
synonym: "positive regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of patterning of blood vessels" EXACT [GOC:TermGenie]
synonym: "up-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of patterning of blood vessels" EXACT [GOC:TermGenie]
synonym: "upregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of patterning of blood vessels" EXACT [GOC:TermGenie]
is_a: GO:0045766 ! positive regulation of angiogenesis
is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium
is_a: GO:1905553 ! regulation of blood vessel branching
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis
relationship: positively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis
created_by: nc
creation_date: 2016-10-12T14:19:49Z

[Term]
id: GO:1905557
name: regulation of mitotic nuclear envelope disassembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790]
synonym: "regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie]
synonym: "regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie]
synonym: "regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie]
is_a: GO:0010549 ! regulation of membrane disassembly
is_a: GO:0010564 ! regulation of cell cycle process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007077 ! mitotic nuclear membrane disassembly
relationship: regulates GO:0007077 ! mitotic nuclear membrane disassembly
created_by: hbye
creation_date: 2016-10-14T13:14:57Z

[Term]
id: GO:1905558
name: negative regulation of mitotic nuclear envelope disassembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790]
synonym: "down regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie]
synonym: "down regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie]
synonym: "down regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie]
synonym: "down-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie]
synonym: "down-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie]
synonym: "downregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie]
synonym: "downregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie]
synonym: "downregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie]
synonym: "inhibition of mitotic nuclear envelope breakdown" NARROW [GOC:TermGenie]
synonym: "inhibition of mitotic nuclear envelope catabolism" NARROW [GOC:TermGenie]
synonym: "inhibition of mitotic nuclear envelope degradation" NARROW [GOC:TermGenie]
synonym: "inhibition of mitotic nuclear envelope disassembly" NARROW [GOC:TermGenie]
synonym: "negative regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie]
synonym: "negative regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie]
is_a: GO:0010948 ! negative regulation of cell cycle process
is_a: GO:0051129 ! negative regulation of cellular component organization
is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007077 ! mitotic nuclear membrane disassembly
relationship: negatively_regulates GO:0007077 ! mitotic nuclear membrane disassembly
created_by: hbye
creation_date: 2016-10-14T13:15:08Z

[Term]
id: GO:1905559
name: positive regulation of mitotic nuclear envelope disassembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790]
synonym: "activation of mitotic nuclear envelope breakdown" NARROW [GOC:TermGenie]
synonym: "activation of mitotic nuclear envelope catabolism" NARROW [GOC:TermGenie]
synonym: "activation of mitotic nuclear envelope degradation" NARROW [GOC:TermGenie]
synonym: "activation of mitotic nuclear envelope disassembly" NARROW [GOC:TermGenie]
synonym: "positive regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie]
synonym: "positive regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie]
synonym: "up regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie]
synonym: "up regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie]
synonym: "up regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie]
synonym: "up-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie]
synonym: "up-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie]
synonym: "upregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie]
synonym: "upregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie]
synonym: "upregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie]
is_a: GO:0051130 ! positive regulation of cellular component organization
is_a: GO:0090068 ! positive regulation of cell cycle process
is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007077 ! mitotic nuclear membrane disassembly
relationship: positively_regulates GO:0007077 ! mitotic nuclear membrane disassembly
created_by: hbye
creation_date: 2016-10-14T13:15:17Z

[Term]
id: GO:1905562
name: regulation of vascular endothelial cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774]
is_a: GO:0001936 ! regulation of endothelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0101023 ! vascular endothelial cell proliferation
relationship: regulates GO:0101023 ! vascular endothelial cell proliferation
created_by: nc
creation_date: 2016-10-17T09:24:17Z

[Term]
id: GO:1905563
name: negative regulation of vascular endothelial cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774]
synonym: "down regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie]
synonym: "inhibition of vascular endothelial cell proliferation" NARROW [GOC:TermGenie]
is_a: GO:0001937 ! negative regulation of endothelial cell proliferation
is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0101023 ! vascular endothelial cell proliferation
relationship: negatively_regulates GO:0101023 ! vascular endothelial cell proliferation
created_by: nc
creation_date: 2016-10-17T09:24:26Z

[Term]
id: GO:1905564
name: positive regulation of vascular endothelial cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774]
synonym: "activation of vascular endothelial cell proliferation" NARROW [GOC:TermGenie]
synonym: "up regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0001938 ! positive regulation of endothelial cell proliferation
is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0101023 ! vascular endothelial cell proliferation
relationship: positively_regulates GO:0101023 ! vascular endothelial cell proliferation
created_by: nc
creation_date: 2016-10-17T09:24:35Z

[Term]
id: GO:1905606
name: regulation of presynapse assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483]
subset: goslim_synapse
synonym: "regulation of presynapse biogenesis" EXACT [GOC:TermGenie]
synonym: "regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie]
is_a: GO:0051963 ! regulation of synapse assembly
is_a: GO:0099174 ! regulation of presynapse organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0099054 ! presynapse assembly
relationship: regulates GO:0099054 ! presynapse assembly
created_by: bc
creation_date: 2016-10-27T16:08:13Z

[Term]
id: GO:1905607
name: negative regulation of presynapse assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483]
synonym: "down regulation of presynapse assembly" EXACT [GOC:TermGenie]
synonym: "down regulation of presynapse biogenesis" EXACT [GOC:TermGenie]
synonym: "down regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of presynapse assembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of presynapse biogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of presynapse assembly" EXACT [GOC:TermGenie]
synonym: "downregulation of presynapse biogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie]
synonym: "inhibition of presynapse assembly" NARROW [GOC:TermGenie]
synonym: "inhibition of presynapse biogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of presynaptic terminal assembly" NARROW [GOC:TermGenie]
synonym: "negative regulation of presynapse biogenesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie]
is_a: GO:0051964 ! negative regulation of synapse assembly
is_a: GO:1905606 ! regulation of presynapse assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0099054 ! presynapse assembly
relationship: negatively_regulates GO:0099054 ! presynapse assembly
created_by: bc
creation_date: 2016-10-27T16:08:20Z

[Term]
id: GO:1905608
name: positive regulation of presynapse assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483]
synonym: "activation of presynapse assembly" NARROW [GOC:TermGenie]
synonym: "activation of presynapse biogenesis" NARROW [GOC:TermGenie]
synonym: "activation of presynaptic terminal assembly" NARROW [GOC:TermGenie]
synonym: "positive regulation of presynapse biogenesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie]
synonym: "up regulation of presynapse assembly" EXACT [GOC:TermGenie]
synonym: "up regulation of presynapse biogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of presynapse assembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of presynapse biogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of presynapse assembly" EXACT [GOC:TermGenie]
synonym: "upregulation of presynapse biogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie]
is_a: GO:0051130 ! positive regulation of cellular component organization
is_a: GO:1905606 ! regulation of presynapse assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0099054 ! presynapse assembly
relationship: positively_regulates GO:0099054 ! presynapse assembly
created_by: bc
creation_date: 2016-10-27T16:08:28Z

[Term]
id: GO:1905627
name: regulation of serotonin biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596]
synonym: "regulation of serotonin anabolism" EXACT [GOC:TermGenie]
synonym: "regulation of serotonin biosynthesis" EXACT [GOC:TermGenie]
synonym: "regulation of serotonin formation" EXACT [GOC:TermGenie]
synonym: "regulation of serotonin synthesis" EXACT [GOC:TermGenie]
is_a: GO:0009889 ! regulation of biosynthetic process
is_a: GO:0031323 ! regulation of cellular metabolic process
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0042427 ! serotonin biosynthetic process
relationship: regulates GO:0042427 ! serotonin biosynthetic process
created_by: pad
creation_date: 2016-10-31T14:26:20Z

[Term]
id: GO:1905628
name: negative regulation of serotonin biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596]
synonym: "down regulation of serotonin anabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of serotonin biosynthesis" EXACT [GOC:TermGenie]
synonym: "down regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down regulation of serotonin formation" EXACT [GOC:TermGenie]
synonym: "down regulation of serotonin synthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of serotonin anabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of serotonin formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of serotonin synthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of serotonin anabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of serotonin biosynthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie]
synonym: "downregulation of serotonin formation" EXACT [GOC:TermGenie]
synonym: "downregulation of serotonin synthesis" EXACT [GOC:TermGenie]
synonym: "inhibition of serotonin anabolism" NARROW [GOC:TermGenie]
synonym: "inhibition of serotonin biosynthesis" NARROW [GOC:TermGenie]
synonym: "inhibition of serotonin biosynthetic process" NARROW [GOC:TermGenie]
synonym: "inhibition of serotonin formation" NARROW [GOC:TermGenie]
synonym: "inhibition of serotonin synthesis" NARROW [GOC:TermGenie]
synonym: "negative regulation of serotonin anabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of serotonin biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of serotonin formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of serotonin synthesis" EXACT [GOC:TermGenie]
is_a: GO:0009890 ! negative regulation of biosynthetic process
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process
is_a: GO:1905627 ! regulation of serotonin biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0042427 ! serotonin biosynthetic process
relationship: negatively_regulates GO:0042427 ! serotonin biosynthetic process
created_by: pad
creation_date: 2016-10-31T14:26:28Z

[Term]
id: GO:1905629
name: positive regulation of serotonin biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596]
synonym: "activation of serotonin anabolism" NARROW [GOC:TermGenie]
synonym: "activation of serotonin biosynthesis" NARROW [GOC:TermGenie]
synonym: "activation of serotonin biosynthetic process" NARROW [GOC:TermGenie]
synonym: "activation of serotonin formation" NARROW [GOC:TermGenie]
synonym: "activation of serotonin synthesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of serotonin anabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of serotonin biosynthesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of serotonin formation" EXACT [GOC:TermGenie]
synonym: "positive regulation of serotonin synthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of serotonin anabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of serotonin biosynthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up regulation of serotonin formation" EXACT [GOC:TermGenie]
synonym: "up regulation of serotonin synthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of serotonin anabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of serotonin formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of serotonin synthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of serotonin anabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of serotonin biosynthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of serotonin formation" EXACT [GOC:TermGenie]
synonym: "upregulation of serotonin synthesis" EXACT [GOC:TermGenie]
is_a: GO:0009891 ! positive regulation of biosynthetic process
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process
is_a: GO:1905627 ! regulation of serotonin biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0042427 ! serotonin biosynthetic process
relationship: positively_regulates GO:0042427 ! serotonin biosynthetic process
created_by: pad
creation_date: 2016-10-31T14:26:36Z

[Term]
id: GO:1905634
name: regulation of protein localization to chromatin
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to chromatin." [GO_REF:0000058, GOC:TermGenie, PMID:20889714]
synonym: "regulation of protein localisation to chromatin" EXACT [GOC:TermGenie]
is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0071168 ! protein localization to chromatin
relationship: regulates GO:0071168 ! protein localization to chromatin
created_by: pga
creation_date: 2016-11-01T16:33:52Z

[Term]
id: GO:1905651
name: regulation of artery morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411]
synonym: "regulation of arterial morphogenesis" EXACT [GOC:TermGenie]
synonym: "regulation of arteriogenesis" EXACT [GOC:TermGenie]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048844 ! artery morphogenesis
relationship: regulates GO:0048844 ! artery morphogenesis
created_by: rph
creation_date: 2016-11-09T12:19:37Z

[Term]
id: GO:1905652
name: negative regulation of artery morphogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411]
synonym: "down regulation of arterial morphogenesis" EXACT [GOC:TermGenie]
synonym: "down regulation of arteriogenesis" EXACT [GOC:TermGenie]
synonym: "down regulation of artery morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of arterial morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of arteriogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of artery morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of arterial morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of arteriogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of artery morphogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of arterial morphogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of arteriogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of artery morphogenesis" NARROW [GOC:TermGenie]
synonym: "negative regulation of arterial morphogenesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of arteriogenesis" EXACT [GOC:TermGenie]
is_a: GO:1905651 ! regulation of artery morphogenesis
is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048844 ! artery morphogenesis
relationship: negatively_regulates GO:0048844 ! artery morphogenesis
created_by: rph
creation_date: 2016-11-09T12:19:53Z

[Term]
id: GO:1905653
name: positive regulation of artery morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411]
synonym: "activation of arterial morphogenesis" NARROW [GOC:TermGenie]
synonym: "activation of arteriogenesis" NARROW [GOC:TermGenie]
synonym: "activation of artery morphogenesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of arterial morphogenesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of arteriogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of arterial morphogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of arteriogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of artery morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of arterial morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of arteriogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of artery morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of arterial morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of arteriogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of artery morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:1905651 ! regulation of artery morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048844 ! artery morphogenesis
relationship: positively_regulates GO:0048844 ! artery morphogenesis
created_by: rph
creation_date: 2016-11-09T12:20:01Z

[Term]
id: GO:1905690
name: nucleus disassembly
namespace: biological_process
def: "The disaggregation of a nucleus into its constituent components." [GO_REF:0000079, GOC:autophagy, GOC:pr, GOC:TermGenie]
synonym: "cell nucleus disassembly" EXACT [GOC:TermGenie]
is_a: GO:0006997 ! nucleus organization
is_a: GO:1903008 ! organelle disassembly
intersection_of: GO:0022411 ! cellular component disassembly
intersection_of: results_in_disassembly_of GO:0005634 ! nucleus
relationship: results_in_disassembly_of GO:0005634 ! nucleus
created_by: pr
creation_date: 2016-11-14T13:38:57Z

[Term]
id: GO:1905720
name: cytoplasmic microtubule bundle
namespace: cellular_component
def: "Any microtubule bundle that is part of a cytoplasm." [GO_REF:0000064, GOC:TermGenie, PMID:11007487, PMID:26124291]
synonym: "microtubule bundle of cytoplasm" EXACT [GOC:TermGenie]
synonym: "microtubule fascicle of cytoplasm" EXACT [GOC:TermGenie]
is_a: GO:0097427 ! microtubule bundle
intersection_of: GO:0097427 ! microtubule bundle
intersection_of: part_of GO:0005737 ! cytoplasm
relationship: part_of GO:0005737 ! cytoplasm
created_by: mah
creation_date: 2016-11-24T16:52:02Z

[Term]
id: GO:1905755
name: protein localization to cytoplasmic microtubule
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule." [GO_REF:0000087, GOC:TermGenie, PMID:15177031]
synonym: "protein localisation to cytoplasmic microtubule" EXACT [GOC:TermGenie]
is_a: GO:0035372 ! protein localization to microtubule
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0005881 ! cytoplasmic microtubule
relationship: has_target_end_location GO:0005881 ! cytoplasmic microtubule
created_by: mah
creation_date: 2016-12-12T15:31:07Z

[Term]
id: GO:1905770
name: regulation of mesodermal cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923]
synonym: "regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048333 ! mesodermal cell differentiation
relationship: regulates GO:0048333 ! mesodermal cell differentiation
created_by: rph
creation_date: 2016-12-21T12:44:13Z

[Term]
id: GO:1905771
name: negative regulation of mesodermal cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923]
synonym: "down regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "down regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "down-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "downregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie]
synonym: "inhibition of mesoderm cell differentiation" NARROW [GOC:TermGenie]
synonym: "inhibition of mesodermal cell differentiation" NARROW [GOC:TermGenie]
synonym: "negative regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:1905770 ! regulation of mesodermal cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048333 ! mesodermal cell differentiation
relationship: negatively_regulates GO:0048333 ! mesodermal cell differentiation
created_by: rph
creation_date: 2016-12-21T12:44:23Z

[Term]
id: GO:1905772
name: positive regulation of mesodermal cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923]
synonym: "activation of mesoderm cell differentiation" NARROW [GOC:TermGenie]
synonym: "activation of mesodermal cell differentiation" NARROW [GOC:TermGenie]
synonym: "positive regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "up regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "up-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie]
synonym: "upregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie]
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:1905770 ! regulation of mesodermal cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048333 ! mesodermal cell differentiation
relationship: positively_regulates GO:0048333 ! mesodermal cell differentiation
created_by: rph
creation_date: 2016-12-21T12:44:32Z

[Term]
id: GO:1905806
name: regulation of synapse pruning
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093]
subset: goslim_synapse
synonym: "regulation of synapse clearance" EXACT []
synonym: "regulation of synapse disassembly" EXACT syngo_official_label []
synonym: "regulation of synapse elimination" EXACT []
synonym: "regulation of synapse removal" EXACT []
is_a: GO:0050807 ! regulation of synapse organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0098883 ! synapse pruning
relationship: regulates GO:0098883 ! synapse pruning
created_by: tb
creation_date: 2017-01-11T22:03:15Z

[Term]
id: GO:1905807
name: negative regulation of synapse pruning
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093]
synonym: "down regulation of synapse disassembly" EXACT [GOC:TermGenie]
synonym: "down-regulation of synapse disassembly" EXACT [GOC:TermGenie]
synonym: "downregulation of synapse disassembly" EXACT [GOC:TermGenie]
synonym: "inhibition of synapse disassembly" NARROW [GOC:TermGenie]
synonym: "regulation of synapse clearance" BROAD []
synonym: "regulation of synapse disassembly" BROAD []
synonym: "regulation of synapse elimination" BROAD []
synonym: "regulation of synapse removal" BROAD []
is_a: GO:1905806 ! regulation of synapse pruning
is_a: GO:1905809 ! negative regulation of synapse organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0098883 ! synapse pruning
relationship: negatively_regulates GO:0098883 ! synapse pruning
created_by: tb
creation_date: 2017-01-11T22:03:24Z

[Term]
id: GO:1905808
name: positive regulation of synapse pruning
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093]
synonym: "activation of synapse disassembly" NARROW [GOC:TermGenie]
synonym: "regulation of synapse clearance" BROAD []
synonym: "regulation of synapse disassembly" BROAD []
synonym: "regulation of synapse elimination" BROAD []
synonym: "regulation of synapse removal" BROAD []
synonym: "up regulation of synapse disassembly" EXACT [GOC:TermGenie]
synonym: "up-regulation of synapse disassembly" EXACT [GOC:TermGenie]
synonym: "upregulation of synapse disassembly" EXACT [GOC:TermGenie]
is_a: GO:0051130 ! positive regulation of cellular component organization
is_a: GO:1905806 ! regulation of synapse pruning
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0098883 ! synapse pruning
relationship: positively_regulates GO:0098883 ! synapse pruning
created_by: tb
creation_date: 2017-01-11T22:03:33Z

[Term]
id: GO:1905809
name: negative regulation of synapse organization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization." [GO_REF:0000058, GOC:TermGenie, PMID:27779093]
synonym: "down regulation of synapse development" EXACT [GOC:TermGenie]
synonym: "down regulation of synapse morphogenesis" RELATED [GOC:TermGenie]
synonym: "down regulation of synapse organisation" EXACT [GOC:TermGenie]
synonym: "down regulation of synapse organization" EXACT [GOC:TermGenie]
synonym: "down regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "down-regulation of synapse development" EXACT [GOC:TermGenie]
synonym: "down-regulation of synapse morphogenesis" RELATED [GOC:TermGenie]
synonym: "down-regulation of synapse organisation" EXACT [GOC:TermGenie]
synonym: "down-regulation of synapse organization" EXACT [GOC:TermGenie]
synonym: "down-regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "downregulation of synapse development" EXACT [GOC:TermGenie]
synonym: "downregulation of synapse morphogenesis" RELATED [GOC:TermGenie]
synonym: "downregulation of synapse organisation" EXACT [GOC:TermGenie]
synonym: "downregulation of synapse organization" EXACT [GOC:TermGenie]
synonym: "downregulation of synapse organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "inhibition of synapse development" NARROW [GOC:TermGenie]
synonym: "inhibition of synapse morphogenesis" RELATED [GOC:TermGenie]
synonym: "inhibition of synapse organisation" NARROW [GOC:TermGenie]
synonym: "inhibition of synapse organization" NARROW [GOC:TermGenie]
synonym: "inhibition of synapse organization and biogenesis" RELATED [GOC:TermGenie]
synonym: "negative regulation of synapse development" EXACT [GOC:TermGenie]
synonym: "negative regulation of synapse morphogenesis" RELATED [GOC:TermGenie]
synonym: "negative regulation of synapse organisation" EXACT [GOC:TermGenie]
synonym: "negative regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie]
is_a: GO:0050807 ! regulation of synapse organization
is_a: GO:0051129 ! negative regulation of cellular component organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0050808 ! synapse organization
relationship: negatively_regulates GO:0050808 ! synapse organization
created_by: tb
creation_date: 2017-01-11T22:03:41Z

[Term]
id: GO:1905821
name: positive regulation of chromosome condensation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of chromosome condensation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:17268547]
synonym: "activation of chromosome condensation" NARROW [GOC:TermGenie]
synonym: "activation of eukaryotic chromosome condensation" NARROW [GOC:TermGenie]
synonym: "activation of nuclear chromosome condensation" NARROW [GOC:TermGenie]
synonym: "positive regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie]
synonym: "positive regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie]
synonym: "up regulation of chromosome condensation" EXACT [GOC:TermGenie]
synonym: "up regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie]
synonym: "up regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie]
synonym: "up-regulation of chromosome condensation" EXACT [GOC:TermGenie]
synonym: "up-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie]
synonym: "up-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie]
synonym: "upregulation of chromosome condensation" EXACT [GOC:TermGenie]
synonym: "upregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie]
synonym: "upregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie]
is_a: GO:0060623 ! regulation of chromosome condensation
is_a: GO:2001252 ! positive regulation of chromosome organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030261 ! chromosome condensation
relationship: positively_regulates GO:0030261 ! chromosome condensation
created_by: bhm
creation_date: 2017-01-13T14:13:44Z

[Term]
id: GO:1905833
name: negative regulation of microtubule nucleation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation." [GO_REF:0000058, GOC:TermGenie, PMID:27689799]
synonym: "down regulation of microtubule nucleation" EXACT [GOC:TermGenie]
synonym: "down-regulation of microtubule nucleation" EXACT [GOC:TermGenie]
synonym: "downregulation of microtubule nucleation" EXACT [GOC:TermGenie]
synonym: "inhibition of microtubule nucleation" NARROW [GOC:TermGenie]
is_a: GO:0010968 ! regulation of microtubule nucleation
is_a: GO:0031115 ! negative regulation of microtubule polymerization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007020 ! microtubule nucleation
relationship: negatively_regulates GO:0007020 ! microtubule nucleation
created_by: hbye
creation_date: 2017-01-17T12:00:56Z

[Term]
id: GO:1905867
name: epididymis development
namespace: biological_process
def: "The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12388089]
synonym: "epididymus development" EXACT [GOC:TermGenie]
is_a: GO:0035295 ! tube development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0001301 ! epididymis
relationship: results_in_development_of UBERON:0001301 ! epididymis
created_by: sl
creation_date: 2017-01-27T00:00:33Z

[Term]
id: GO:1905871
name: regulation of protein localization to cell leading edge
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884]
synonym: "regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie]
synonym: "regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie]
synonym: "regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie]
is_a: GO:0032880 ! regulation of protein localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:1902463 ! protein localization to cell leading edge
relationship: regulates GO:1902463 ! protein localization to cell leading edge
created_by: sl
creation_date: 2017-01-27T19:34:55Z

[Term]
id: GO:1905872
name: negative regulation of protein localization to cell leading edge
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884]
synonym: "down regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie]
synonym: "down regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie]
synonym: "down-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie]
synonym: "downregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie]
synonym: "inhibition of protein localisation in cell leading edge" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localisation to cell leading edge" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization in cell leading edge" NARROW [GOC:TermGenie]
synonym: "inhibition of protein localization to cell leading edge" NARROW [GOC:TermGenie]
synonym: "negative regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie]
synonym: "negative regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie]
is_a: GO:1903828 ! negative regulation of protein localization
is_a: GO:1905871 ! regulation of protein localization to cell leading edge
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:1902463 ! protein localization to cell leading edge
relationship: negatively_regulates GO:1902463 ! protein localization to cell leading edge
created_by: sl
creation_date: 2017-01-27T19:35:04Z

[Term]
id: GO:1905873
name: positive regulation of protein localization to cell leading edge
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884]
synonym: "activation of protein localisation in cell leading edge" NARROW [GOC:TermGenie]
synonym: "activation of protein localisation to cell leading edge" NARROW [GOC:TermGenie]
synonym: "activation of protein localization in cell leading edge" NARROW [GOC:TermGenie]
synonym: "activation of protein localization to cell leading edge" NARROW [GOC:TermGenie]
synonym: "positive regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie]
synonym: "positive regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie]
synonym: "up regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie]
synonym: "up-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie]
synonym: "upregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie]
is_a: GO:1903829 ! positive regulation of protein localization
is_a: GO:1905871 ! regulation of protein localization to cell leading edge
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:1902463 ! protein localization to cell leading edge
relationship: positively_regulates GO:1902463 ! protein localization to cell leading edge
created_by: sl
creation_date: 2017-01-27T19:35:13Z

[Term]
id: GO:1905879
name: regulation of oogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723]
synonym: "regulation of ovum development" EXACT [GOC:TermGenie]
is_a: GO:0051239 ! regulation of multicellular organismal process
is_a: GO:0060284 ! regulation of cell development
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048477 ! oogenesis
relationship: regulates GO:0048477 ! oogenesis
created_by: hbye
creation_date: 2017-01-31T09:31:05Z

[Term]
id: GO:1905880
name: negative regulation of oogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723]
synonym: "down regulation of oogenesis" EXACT [GOC:TermGenie]
synonym: "down regulation of ovum development" EXACT [GOC:TermGenie]
synonym: "down-regulation of oogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of ovum development" EXACT [GOC:TermGenie]
synonym: "downregulation of oogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of ovum development" EXACT [GOC:TermGenie]
synonym: "inhibition of oogenesis" NARROW [GOC:TermGenie]
synonym: "inhibition of ovum development" NARROW [GOC:TermGenie]
synonym: "negative regulation of ovum development" EXACT [GOC:TermGenie]
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1905879 ! regulation of oogenesis
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048477 ! oogenesis
relationship: negatively_regulates GO:0048477 ! oogenesis
created_by: hbye
creation_date: 2017-01-31T09:31:15Z

[Term]
id: GO:1905881
name: positive regulation of oogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723]
synonym: "activation of oogenesis" NARROW [GOC:TermGenie]
synonym: "activation of ovum development" NARROW [GOC:TermGenie]
synonym: "positive regulation of ovum development" EXACT [GOC:TermGenie]
synonym: "up regulation of oogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of ovum development" EXACT [GOC:TermGenie]
synonym: "up-regulation of oogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of ovum development" EXACT [GOC:TermGenie]
synonym: "upregulation of oogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of ovum development" EXACT [GOC:TermGenie]
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1905879 ! regulation of oogenesis
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048477 ! oogenesis
relationship: positively_regulates GO:0048477 ! oogenesis
created_by: hbye
creation_date: 2017-01-31T09:31:23Z

[Term]
id: GO:1905899
name: regulation of smooth muscle tissue development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716]
is_a: GO:1901861 ! regulation of muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048745 ! smooth muscle tissue development
relationship: regulates GO:0048745 ! smooth muscle tissue development
created_by: bhm
creation_date: 2017-02-01T14:31:16Z

[Term]
id: GO:1905900
name: negative regulation of smooth muscle tissue development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716]
synonym: "down regulation of smooth muscle tissue development" EXACT [GOC:TermGenie]
synonym: "down-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie]
synonym: "downregulation of smooth muscle tissue development" EXACT [GOC:TermGenie]
synonym: "inhibition of smooth muscle tissue development" NARROW [GOC:TermGenie]
is_a: GO:1901862 ! negative regulation of muscle tissue development
is_a: GO:1905899 ! regulation of smooth muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048745 ! smooth muscle tissue development
relationship: negatively_regulates GO:0048745 ! smooth muscle tissue development
created_by: bhm
creation_date: 2017-02-01T14:31:24Z

[Term]
id: GO:1905901
name: positive regulation of smooth muscle tissue development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716]
synonym: "activation of smooth muscle tissue development" NARROW [GOC:TermGenie]
synonym: "up regulation of smooth muscle tissue development" EXACT [GOC:TermGenie]
synonym: "up-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie]
synonym: "upregulation of smooth muscle tissue development" EXACT [GOC:TermGenie]
is_a: GO:1901863 ! positive regulation of muscle tissue development
is_a: GO:1905899 ! regulation of smooth muscle tissue development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048745 ! smooth muscle tissue development
relationship: positively_regulates GO:0048745 ! smooth muscle tissue development
created_by: bhm
creation_date: 2017-02-01T14:31:33Z

[Term]
id: GO:1905902
name: regulation of mesoderm formation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001707 ! mesoderm formation
relationship: regulates GO:0001707 ! mesoderm formation
created_by: rph
creation_date: 2017-02-03T12:28:20Z

[Term]
id: GO:1905903
name: negative regulation of mesoderm formation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491]
synonym: "down regulation of mesoderm formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of mesoderm formation" EXACT [GOC:TermGenie]
synonym: "downregulation of mesoderm formation" EXACT [GOC:TermGenie]
synonym: "inhibition of mesoderm formation" NARROW [GOC:TermGenie]
is_a: GO:1905902 ! regulation of mesoderm formation
is_a: GO:2000381 ! negative regulation of mesoderm development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001707 ! mesoderm formation
relationship: negatively_regulates GO:0001707 ! mesoderm formation
created_by: rph
creation_date: 2017-02-03T12:28:29Z

[Term]
id: GO:1905904
name: positive regulation of mesoderm formation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491]
synonym: "activation of mesoderm formation" NARROW [GOC:TermGenie]
synonym: "up regulation of mesoderm formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of mesoderm formation" EXACT [GOC:TermGenie]
synonym: "upregulation of mesoderm formation" EXACT [GOC:TermGenie]
is_a: GO:1905902 ! regulation of mesoderm formation
is_a: GO:2000382 ! positive regulation of mesoderm development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001707 ! mesoderm formation
relationship: positively_regulates GO:0001707 ! mesoderm formation
created_by: rph
creation_date: 2017-02-03T12:28:38Z

[Term]
id: GO:1905921
name: regulation of acetylcholine biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328]
synonym: "regulation of acetylcholine anabolism" EXACT [GOC:TermGenie]
synonym: "regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie]
synonym: "regulation of acetylcholine formation" EXACT [GOC:TermGenie]
synonym: "regulation of acetylcholine synthesis" EXACT [GOC:TermGenie]
is_a: GO:0009889 ! regulation of biosynthetic process
is_a: GO:0060408 ! regulation of acetylcholine metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008292 ! acetylcholine biosynthetic process
relationship: regulates GO:0008292 ! acetylcholine biosynthetic process
created_by: bc
creation_date: 2017-02-08T13:08:30Z

[Term]
id: GO:1905922
name: negative regulation of acetylcholine biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328]
synonym: "down regulation of acetylcholine anabolism" EXACT [GOC:TermGenie]
synonym: "down regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie]
synonym: "down regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down regulation of acetylcholine formation" EXACT [GOC:TermGenie]
synonym: "down regulation of acetylcholine synthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie]
synonym: "down-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie]
synonym: "down-regulation of acetylcholine formation" EXACT [GOC:TermGenie]
synonym: "down-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of acetylcholine anabolism" EXACT [GOC:TermGenie]
synonym: "downregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie]
synonym: "downregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie]
synonym: "downregulation of acetylcholine formation" EXACT [GOC:TermGenie]
synonym: "downregulation of acetylcholine synthesis" EXACT [GOC:TermGenie]
synonym: "inhibition of acetylcholine anabolism" NARROW [GOC:TermGenie]
synonym: "inhibition of acetylcholine biosynthesis" NARROW [GOC:TermGenie]
synonym: "inhibition of acetylcholine biosynthetic process" NARROW [GOC:TermGenie]
synonym: "inhibition of acetylcholine formation" NARROW [GOC:TermGenie]
synonym: "inhibition of acetylcholine synthesis" NARROW [GOC:TermGenie]
synonym: "negative regulation of acetylcholine anabolism" EXACT [GOC:TermGenie]
synonym: "negative regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie]
synonym: "negative regulation of acetylcholine formation" EXACT [GOC:TermGenie]
synonym: "negative regulation of acetylcholine synthesis" EXACT [GOC:TermGenie]
is_a: GO:0009890 ! negative regulation of biosynthetic process
is_a: GO:0060410 ! negative regulation of acetylcholine metabolic process
is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008292 ! acetylcholine biosynthetic process
relationship: negatively_regulates GO:0008292 ! acetylcholine biosynthetic process
created_by: bc
creation_date: 2017-02-08T13:08:39Z

[Term]
id: GO:1905923
name: positive regulation of acetylcholine biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328]
synonym: "activation of acetylcholine anabolism" NARROW [GOC:TermGenie]
synonym: "activation of acetylcholine biosynthesis" NARROW [GOC:TermGenie]
synonym: "activation of acetylcholine biosynthetic process" NARROW [GOC:TermGenie]
synonym: "activation of acetylcholine formation" NARROW [GOC:TermGenie]
synonym: "activation of acetylcholine synthesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of acetylcholine anabolism" EXACT [GOC:TermGenie]
synonym: "positive regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie]
synonym: "positive regulation of acetylcholine formation" EXACT [GOC:TermGenie]
synonym: "positive regulation of acetylcholine synthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of acetylcholine anabolism" EXACT [GOC:TermGenie]
synonym: "up regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie]
synonym: "up regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up regulation of acetylcholine formation" EXACT [GOC:TermGenie]
synonym: "up regulation of acetylcholine synthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie]
synonym: "up-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie]
synonym: "up-regulation of acetylcholine formation" EXACT [GOC:TermGenie]
synonym: "up-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of acetylcholine anabolism" EXACT [GOC:TermGenie]
synonym: "upregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie]
synonym: "upregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie]
synonym: "upregulation of acetylcholine formation" EXACT [GOC:TermGenie]
synonym: "upregulation of acetylcholine synthesis" EXACT [GOC:TermGenie]
is_a: GO:0009891 ! positive regulation of biosynthetic process
is_a: GO:0060409 ! positive regulation of acetylcholine metabolic process
is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008292 ! acetylcholine biosynthetic process
relationship: positively_regulates GO:0008292 ! acetylcholine biosynthetic process
created_by: bc
creation_date: 2017-02-08T13:08:48Z

[Term]
id: GO:1905936
name: regulation of germ cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467]
is_a: GO:0042127 ! regulation of cell population proliferation
is_a: GO:0051239 ! regulation of multicellular organismal process
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0036093 ! germ cell proliferation
relationship: regulates GO:0036093 ! germ cell proliferation
created_by: hbye
creation_date: 2017-02-09T14:51:31Z

[Term]
id: GO:1905937
name: negative regulation of germ cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467]
synonym: "down regulation of germ cell proliferation" EXACT [GOC:TermGenie]
synonym: "down-regulation of germ cell proliferation" EXACT [GOC:TermGenie]
synonym: "downregulation of germ cell proliferation" EXACT [GOC:TermGenie]
synonym: "inhibition of germ cell proliferation" NARROW [GOC:TermGenie]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1905936 ! regulation of germ cell proliferation
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0036093 ! germ cell proliferation
relationship: negatively_regulates GO:0036093 ! germ cell proliferation
created_by: hbye
creation_date: 2017-02-09T14:51:41Z

[Term]
id: GO:1905938
name: positive regulation of germ cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467]
synonym: "activation of germ cell proliferation" NARROW [GOC:TermGenie]
synonym: "up regulation of germ cell proliferation" EXACT [GOC:TermGenie]
synonym: "up-regulation of germ cell proliferation" EXACT [GOC:TermGenie]
synonym: "upregulation of germ cell proliferation" EXACT [GOC:TermGenie]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1905936 ! regulation of germ cell proliferation
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0036093 ! germ cell proliferation
relationship: positively_regulates GO:0036093 ! germ cell proliferation
created_by: hbye
creation_date: 2017-02-09T14:51:51Z

[Term]
id: GO:1905939
name: regulation of gonad development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467]
synonym: "regulation of gonadogenesis" EXACT [GOC:TermGenie]
is_a: GO:0050793 ! regulation of developmental process
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008406 ! gonad development
relationship: regulates GO:0008406 ! gonad development
created_by: hbye
creation_date: 2017-02-09T17:01:50Z

[Term]
id: GO:1905940
name: negative regulation of gonad development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467]
synonym: "down regulation of gonad development" EXACT [GOC:TermGenie]
synonym: "down regulation of gonadogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of gonad development" EXACT [GOC:TermGenie]
synonym: "down-regulation of gonadogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of gonad development" EXACT [GOC:TermGenie]
synonym: "downregulation of gonadogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of gonad development" NARROW [GOC:TermGenie]
synonym: "inhibition of gonadogenesis" NARROW [GOC:TermGenie]
synonym: "negative regulation of gonadogenesis" EXACT [GOC:TermGenie]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1905939 ! regulation of gonad development
is_a: GO:2000242 ! negative regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008406 ! gonad development
relationship: negatively_regulates GO:0008406 ! gonad development
created_by: hbye
creation_date: 2017-02-09T17:01:59Z

[Term]
id: GO:1905941
name: positive regulation of gonad development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467]
synonym: "activation of gonad development" NARROW [GOC:TermGenie]
synonym: "activation of gonadogenesis" NARROW [GOC:TermGenie]
synonym: "positive regulation of gonadogenesis" EXACT [GOC:TermGenie]
synonym: "up regulation of gonad development" EXACT [GOC:TermGenie]
synonym: "up regulation of gonadogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of gonad development" EXACT [GOC:TermGenie]
synonym: "up-regulation of gonadogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of gonad development" EXACT [GOC:TermGenie]
synonym: "upregulation of gonadogenesis" EXACT [GOC:TermGenie]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1905939 ! regulation of gonad development
is_a: GO:2000243 ! positive regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008406 ! gonad development
relationship: positively_regulates GO:0008406 ! gonad development
created_by: hbye
creation_date: 2017-02-09T17:02:08Z

[Term]
id: GO:1905952
name: regulation of lipid localization
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681]
synonym: "regulation of lipid localisation" EXACT [GOC:TermGenie]
is_a: GO:0032879 ! regulation of localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0010876 ! lipid localization
relationship: regulates GO:0010876 ! lipid localization
created_by: rz
creation_date: 2017-02-21T12:12:22Z

[Term]
id: GO:1905953
name: negative regulation of lipid localization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681]
synonym: "down regulation of lipid localisation" EXACT [GOC:TermGenie]
synonym: "down regulation of lipid localization" EXACT [GOC:TermGenie]
synonym: "down-regulation of lipid localisation" EXACT [GOC:TermGenie]
synonym: "down-regulation of lipid localization" EXACT [GOC:TermGenie]
synonym: "downregulation of lipid localisation" EXACT [GOC:TermGenie]
synonym: "downregulation of lipid localization" EXACT [GOC:TermGenie]
synonym: "inhibition of lipid localisation" NARROW [GOC:TermGenie]
synonym: "inhibition of lipid localization" NARROW [GOC:TermGenie]
synonym: "negative regulation of lipid localisation" EXACT [GOC:TermGenie]
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:1905952 ! regulation of lipid localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0010876 ! lipid localization
relationship: negatively_regulates GO:0010876 ! lipid localization
created_by: rz
creation_date: 2017-02-21T12:12:41Z

[Term]
id: GO:1905954
name: positive regulation of lipid localization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681]
synonym: "activation of lipid localisation" NARROW [GOC:TermGenie]
synonym: "activation of lipid localization" NARROW [GOC:TermGenie]
synonym: "positive regulation of lipid localisation" EXACT [GOC:TermGenie]
synonym: "up regulation of lipid localisation" EXACT [GOC:TermGenie]
synonym: "up regulation of lipid localization" EXACT [GOC:TermGenie]
synonym: "up-regulation of lipid localisation" EXACT [GOC:TermGenie]
synonym: "up-regulation of lipid localization" EXACT [GOC:TermGenie]
synonym: "upregulation of lipid localisation" EXACT [GOC:TermGenie]
synonym: "upregulation of lipid localization" EXACT [GOC:TermGenie]
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:1905952 ! regulation of lipid localization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0010876 ! lipid localization
relationship: positively_regulates GO:0010876 ! lipid localization
created_by: rz
creation_date: 2017-02-21T12:12:49Z

[Term]
id: GO:1905955
name: negative regulation of endothelial tube morphogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718]
synonym: "down regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie]
synonym: "down-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie]
synonym: "downregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie]
synonym: "inhibition of endothelial tube morphogenesis" NARROW [GOC:TermGenie]
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:1901509 ! regulation of endothelial tube morphogenesis
is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061154 ! endothelial tube morphogenesis
relationship: negatively_regulates GO:0061154 ! endothelial tube morphogenesis
created_by: rph
creation_date: 2017-02-21T15:17:31Z

[Term]
id: GO:1905956
name: positive regulation of endothelial tube morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718]
synonym: "activation of endothelial tube morphogenesis" NARROW [GOC:TermGenie]
synonym: "up regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie]
synonym: "up-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie]
synonym: "upregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie]
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:1901509 ! regulation of endothelial tube morphogenesis
is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061154 ! endothelial tube morphogenesis
relationship: positively_regulates GO:0061154 ! endothelial tube morphogenesis
created_by: rph
creation_date: 2017-02-21T15:17:39Z

[Term]
id: GO:1990009
name: retinal cell apoptotic process
namespace: biological_process
alt_id: GO:0046674
def: "Any apoptotic process in a retinal cell." [GOC:mtg_apoptosis, PMID:15558487, PMID:24664675]
synonym: "induction of retinal programmed cell death" RELATED []
is_a: GO:0006915 ! apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0009004 ! retinal cell
relationship: occurs_in CL:0009004 ! retinal cell
created_by: pr
creation_date: 2012-12-12T10:15:08Z

[Term]
id: GO:1990010
name: compound eye retinal cell apoptotic process
namespace: biological_process
def: "Any apoptotic process in a compound eye retinal cell." [GOC:mtg_apoptosis, PMID:12021768]
is_a: GO:1990009 ! retinal cell apoptotic process
intersection_of: GO:0006915 ! apoptotic process
intersection_of: occurs_in CL:0009001 ! compound eye retinal cell
relationship: occurs_in CL:0009001 ! compound eye retinal cell
created_by: pr
creation_date: 2012-12-12T10:21:07Z

[Term]
id: GO:1990182
name: exosomal secretion
namespace: biological_process
def: "The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:hjd, PMID:10572093, PMID:12154376, PMID:16773132, PMID:18617898]
synonym: "exosomal protein secretion" NARROW [PMID:18617898]
synonym: "exosomal secretory pathway" EXACT [PMID:18617898]
synonym: "extracellular vesicular exosome secretion" EXACT [GOC:hjd]
synonym: "multi-vesicular body fusion with plasma membrane" EXACT []
synonym: "secretion of exosome" EXACT [PMID:18617898]
is_a: GO:0006887 ! exocytosis
is_a: GO:0051650 ! establishment of vesicle localization
intersection_of: GO:0006887 ! exocytosis
intersection_of: has_primary_input GO:0070062 ! extracellular exosome
relationship: has_primary_input GO:0070062 ! extracellular exosome
relationship: part_of GO:0097734 ! extracellular exosome biogenesis
property_value: RO:0002161 NCBITaxon:4890
created_by: hjd
creation_date: 2013-09-04T21:08:14Z

[Term]
id: GO:1990234
name: transferase complex
namespace: cellular_component
def: "A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor)." [GOC:bhm, PMID:16540464]
is_a: GO:1902494 ! catalytic complex
intersection_of: GO:1902494 ! catalytic complex
intersection_of: capable_of GO:0016740 ! transferase activity
relationship: capable_of GO:0016740 ! transferase activity
created_by: bhm
creation_date: 2013-11-12T13:20:12Z

[Term]
id: GO:1990280
name: RNA localization to chromatin
namespace: biological_process
def: "A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin." [GOC:dos, GOC:mah, PMID:22582262]
synonym: "RNA localisation to chromatin" EXACT []
is_a: GO:0006403 ! RNA localization
intersection_of: GO:0006403 ! RNA localization
intersection_of: has_target_end_location GO:0000785 ! chromatin
relationship: has_target_end_location GO:0000785 ! chromatin
created_by: mah
creation_date: 2014-01-30T15:55:34Z

[Term]
id: GO:1990351
name: transporter complex
namespace: cellular_component
def: "A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells." [GOC:bhm, PMID:15449578]
comment: An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay).
is_a: GO:0032991 ! protein-containing complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: capable_of GO:0005215 ! transporter activity
relationship: capable_of GO:0005215 ! transporter activity
created_by: bhm
creation_date: 2014-03-26T14:23:27Z

[Term]
id: GO:1990375
name: baculum development
namespace: biological_process
def: "The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure." [GOC:sl, PMID:21471296]
synonym: "os penis development" EXACT [GOC:sl]
synonym: "penile bone development" EXACT [GOC:sl]
synonym: "penis bone development" EXACT [GOC:sl]
is_a: GO:0048608 ! reproductive structure development
intersection_of: GO:0048856 ! anatomical structure development
intersection_of: results_in_development_of UBERON:0006435 ! os penis
relationship: results_in_development_of UBERON:0006435 ! os penis
created_by: sl
creation_date: 2014-05-01T23:59:13Z

[Term]
id: GO:1990502
name: dense core granule maturation
namespace: biological_process
def: "Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis." [GOC:kmv, PMID:22654674]
synonym: "dense core vesicle maturation" EXACT []
is_a: GO:0061792 ! secretory granule maturation
intersection_of: GO:0021700 ! developmental maturation
intersection_of: results_in_maturation_of GO:0031045 ! dense core granule
relationship: results_in_maturation_of GO:0031045 ! dense core granule
created_by: kmv
creation_date: 2014-09-30T20:35:11Z

[Term]
id: GO:1990705
name: cholangiocyte proliferation
namespace: biological_process
def: "The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water." [PMID:24434010]
synonym: "hepatoblast proliferation" EXACT []
is_a: GO:0050673 ! epithelial cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:1000488 ! cholangiocyte
relationship: acts_on_population_of CL:1000488 ! cholangiocyte
creation_date: 2015-03-16T23:23:50Z

[Term]
id: GO:1990748
name: cellular detoxification
namespace: biological_process
def: "Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:vw]
is_a: GO:0009987 ! cellular process
is_a: GO:0098754 ! detoxification
intersection_of: GO:0098754 ! detoxification
intersection_of: occurs_in CL:0000000 ! cell
relationship: occurs_in CL:0000000 ! cell
relationship: part_of GO:0097237 ! cellular response to toxic substance
created_by: vw
creation_date: 2015-05-18T16:17:46Z

[Term]
id: GO:1990765
name: colon smooth muscle contraction
namespace: biological_process
def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum." [PMID:24170253]
is_a: GO:0006939 ! smooth muscle contraction
intersection_of: GO:0006939 ! smooth muscle contraction
intersection_of: occurs_in UBERON:0001155 ! colon
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: occurs_in UBERON:0001155 ! colon
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of GO:0014827 ! intestine smooth muscle contraction
created_by: sl
creation_date: 2015-06-10T18:29:21Z

[Term]
id: GO:1990768
name: gastric mucosal blood circulation
namespace: biological_process
def: "The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products." [PMID:10807413]
synonym: "stomach mucosal blood circulation" EXACT []
is_a: GO:0008015 ! blood circulation
intersection_of: GO:0008015 ! blood circulation
intersection_of: occurs_in UBERON:0004786 ! gastrointestinal system mucosa
relationship: occurs_in UBERON:0004786 ! gastrointestinal system mucosa
created_by: sl
creation_date: 2015-06-10T20:11:09Z

[Term]
id: GO:1990770
name: small intestine smooth muscle contraction
namespace: biological_process
def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine." [PMID:11991626]
is_a: GO:0006939 ! smooth muscle contraction
intersection_of: GO:0006939 ! smooth muscle contraction
intersection_of: occurs_in UBERON:0002108 ! small intestine
relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata <vertebrates>
relationship: occurs_in UBERON:0002108 ! small intestine
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of GO:0014827 ! intestine smooth muscle contraction
created_by: sl
creation_date: 2015-06-11T18:02:33Z

[Term]
id: GO:1990778
name: protein localization to cell periphery
namespace: biological_process
def: "A process in which a protein is transported to, or maintained in, the cell periphery." [PMID:18216290]
is_a: GO:0008104 ! protein localization
intersection_of: GO:0008104 ! protein localization
intersection_of: has_target_end_location GO:0071944 ! cell periphery
relationship: has_target_end_location GO:0071944 ! cell periphery
creation_date: 2015-06-18T22:37:39Z

[Term]
id: GO:1990849
name: vacuolar localization
namespace: biological_process
def: "Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell." [PMID:26283797]
synonym: "maintenance of vacuolar localization" EXACT []
synonym: "maintenance of vacuolar location" NARROW []
synonym: "maintenance of vacuole localization" EXACT []
synonym: "maintenance of vacuole location" EXACT []
is_a: GO:0051640 ! organelle localization
intersection_of: GO:0051179 ! localization
intersection_of: has_primary_input GO:0005773 ! vacuole
relationship: has_primary_input GO:0005773 ! vacuole
property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22182" xsd:anyURI
created_by: mcc
creation_date: 2015-09-10T08:16:02Z

[Term]
id: GO:1990863
name: acinar cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)." [PMID:9788538]
synonym: "acinic cell proliferation" EXACT []
synonym: "acinous cell proliferation" EXACT []
is_a: GO:0050673 ! epithelial cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000622 ! acinar cell
relationship: acts_on_population_of CL:0000622 ! acinar cell
created_by: sl
creation_date: 2015-09-25T14:26:09Z

[Term]
id: GO:1990874
name: vascular associated smooth muscle cell proliferation
namespace: biological_process
def: "The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [PMID:23246467]
synonym: "vascular smooth muscle cell proliferation" EXACT []
synonym: "VSMC proliferation" EXACT []
is_a: GO:0048659 ! smooth muscle cell proliferation
intersection_of: GO:0008283 ! cell population proliferation
intersection_of: acts_on_population_of CL:0000359 ! vascular associated smooth muscle cell
relationship: acts_on_population_of CL:0000359 ! vascular associated smooth muscle cell
created_by: sl
creation_date: 2015-09-29T16:34:59Z

[Term]
id: GO:1990904
name: ribonucleoprotein complex
namespace: cellular_component
alt_id: GO:0030529
alt_id: GO:1990903
def: "A macromolecular complex that contains both RNA and protein molecules." [GOC:krc, GOC:vesicles]
subset: goslim_pir
synonym: "extracellular ribonucleoprotein complex" NARROW []
synonym: "intracellular ribonucleoprotein complex" NARROW []
synonym: "protein-RNA complex" EXACT []
synonym: "RNA-protein complex" EXACT []
synonym: "RNP" EXACT []
xref: Wikipedia:Ribonucleoprotein
is_a: GO:0032991 ! protein-containing complex
relationship: has_part CHEBI:33697 ! ribonucleic acid
created_by: pr
creation_date: 2015-11-19T12:26:37Z

[Term]
id: GO:1990917
name: ooplasm
namespace: cellular_component
def: "The cytoplasm of an ovum." [PMID:19022436]
is_a: GO:0005737 ! cytoplasm
intersection_of: GO:0005737 ! cytoplasm
intersection_of: part_of CL:0000025 ! egg cell
relationship: part_of CL:0000025 ! egg cell
property_value: RO:0002161 NCBITaxon:4751
created_by: sl
creation_date: 2015-12-10T21:40:16Z

[Term]
id: GO:2000018
name: regulation of male gonad development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf]
synonym: "regulation of testicular development" EXACT [GOC:obol]
synonym: "regulation of testis development" EXACT [GOC:obol]
is_a: GO:1905939 ! regulation of gonad development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008584 ! male gonad development
relationship: regulates GO:0008584 ! male gonad development
created_by: jl
creation_date: 2010-07-15T03:29:05Z

[Term]
id: GO:2000019
name: negative regulation of male gonad development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf]
synonym: "negative regulation of testicular development" EXACT [GOC:obol]
synonym: "negative regulation of testis development" EXACT [GOC:obol]
is_a: GO:1905940 ! negative regulation of gonad development
is_a: GO:2000018 ! regulation of male gonad development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008584 ! male gonad development
relationship: negatively_regulates GO:0008584 ! male gonad development
created_by: jl
creation_date: 2010-07-15T03:29:10Z

[Term]
id: GO:2000020
name: positive regulation of male gonad development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of male gonad development." [GOC:obol]
synonym: "positive regulation of testicular development" EXACT [GOC:obol]
synonym: "positive regulation of testis development" EXACT [GOC:obol]
is_a: GO:1905941 ! positive regulation of gonad development
is_a: GO:2000018 ! regulation of male gonad development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008584 ! male gonad development
relationship: positively_regulates GO:0008584 ! male gonad development
created_by: jl
creation_date: 2010-07-15T03:29:13Z

[Term]
id: GO:2000026
name: regulation of multicellular organismal development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of multicellular organismal development." [GOC:obol]
is_a: GO:0050793 ! regulation of developmental process
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007275 ! multicellular organism development
relationship: regulates GO:0007275 ! multicellular organism development
created_by: tb
creation_date: 2010-08-05T11:25:59Z

[Term]
id: GO:2000027
name: regulation of animal organ morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of animal organ morphogenesis." [GOC:obol]
synonym: "regulation of histogenesis and organogenesis" RELATED [GOC:obol]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0009887 ! animal organ morphogenesis
relationship: regulates GO:0009887 ! animal organ morphogenesis
created_by: tb
creation_date: 2010-08-05T11:26:27Z

[Term]
id: GO:2000035
name: regulation of stem cell division
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of stem cell division." [GOC:obol]
synonym: "regulation of stem cell renewal" EXACT [GOC:obol]
is_a: GO:0051302 ! regulation of cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0017145 ! stem cell division
relationship: regulates GO:0017145 ! stem cell division
created_by: tb
creation_date: 2010-08-05T11:34:53Z

[Term]
id: GO:2000036
name: regulation of stem cell population maintenance
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of stem cell population maintenance." [GOC:obol]
synonym: "regulation of maintenance of pluripotency" RELATED [GOC:obol]
is_a: GO:0050793 ! regulation of developmental process
is_a: GO:0051239 ! regulation of multicellular organismal process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0019827 ! stem cell population maintenance
relationship: regulates GO:0019827 ! stem cell population maintenance
created_by: tb
creation_date: 2010-08-05T11:35:25Z

[Term]
id: GO:2000061
name: regulation of ureter smooth muscle cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf]
is_a: GO:0048634 ! regulation of muscle organ development
is_a: GO:0051150 ! regulation of smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072193 ! ureter smooth muscle cell differentiation
relationship: regulates GO:0072193 ! ureter smooth muscle cell differentiation
created_by: jl
creation_date: 2010-08-20T01:44:16Z

[Term]
id: GO:2000062
name: negative regulation of ureter smooth muscle cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf]
is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072193 ! ureter smooth muscle cell differentiation
relationship: negatively_regulates GO:0072193 ! ureter smooth muscle cell differentiation
created_by: jl
creation_date: 2010-08-20T01:44:23Z

[Term]
id: GO:2000063
name: positive regulation of ureter smooth muscle cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf]
is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072193 ! ureter smooth muscle cell differentiation
relationship: positively_regulates GO:0072193 ! ureter smooth muscle cell differentiation
created_by: jl
creation_date: 2010-08-20T01:44:28Z

[Term]
id: GO:2000068
name: regulation of defense response to insect
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of defense response to insect." [GOC:obol]
synonym: "regulation of physiological defense response to insect" EXACT [GOC:obol]
is_a: GO:0031347 ! regulation of defense response
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002213 ! defense response to insect
relationship: regulates GO:0002213 ! defense response to insect
created_by: tb
creation_date: 2010-08-23T09:30:00Z

[Term]
id: GO:2000074
name: regulation of type B pancreatic cell development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf]
synonym: "regulation of pancreatic B cell development" EXACT [GOC:mah]
synonym: "regulation of pancreatic beta cell development" EXACT [GOC:obol]
is_a: GO:0060284 ! regulation of cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003323 ! type B pancreatic cell development
relationship: regulates GO:0003323 ! type B pancreatic cell development
created_by: tb
creation_date: 2010-08-27T11:19:37Z

[Term]
id: GO:2000077
name: negative regulation of type B pancreatic cell development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf]
synonym: "negative regulation of pancreatic B cell development" EXACT [GOC:mah]
synonym: "negative regulation of pancreatic beta cell development" EXACT [GOC:obol]
is_a: GO:0010721 ! negative regulation of cell development
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:2000074 ! regulation of type B pancreatic cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003323 ! type B pancreatic cell development
relationship: negatively_regulates GO:0003323 ! type B pancreatic cell development
created_by: tb
creation_date: 2010-08-27T11:21:17Z

[Term]
id: GO:2000078
name: positive regulation of type B pancreatic cell development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf]
synonym: "positive regulation of pancreatic B cell development" EXACT [GOC:mah]
synonym: "positive regulation of pancreatic beta cell development" EXACT [GOC:obol]
is_a: GO:0010720 ! positive regulation of cell development
is_a: GO:0030858 ! positive regulation of epithelial cell differentiation
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:2000074 ! regulation of type B pancreatic cell development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003323 ! type B pancreatic cell development
relationship: positively_regulates GO:0003323 ! type B pancreatic cell development
created_by: tb
creation_date: 2010-08-27T11:21:19Z

[Term]
id: GO:2000084
name: regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10]
synonym: "regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol]
is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
relationship: regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
created_by: dph
creation_date: 2010-09-03T06:06:41Z

[Term]
id: GO:2000085
name: negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10]
synonym: "negative regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol]
is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
relationship: negatively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
created_by: dph
creation_date: 2010-09-03T06:08:21Z

[Term]
id: GO:2000086
name: positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10]
synonym: "positive regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol]
is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
relationship: positively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
created_by: dph
creation_date: 2010-09-03T06:08:24Z

[Term]
id: GO:2000106
name: regulation of leukocyte apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis]
synonym: "regulation of leukocyte apoptosis" NARROW []
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0071887 ! leukocyte apoptotic process
relationship: regulates GO:0071887 ! leukocyte apoptotic process
created_by: mah
creation_date: 2010-09-15T01:42:05Z

[Term]
id: GO:2000107
name: negative regulation of leukocyte apoptotic process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis]
synonym: "negative regulation of leukocyte apoptosis" NARROW []
is_a: GO:0043066 ! negative regulation of apoptotic process
is_a: GO:2000106 ! regulation of leukocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0071887 ! leukocyte apoptotic process
relationship: negatively_regulates GO:0071887 ! leukocyte apoptotic process
created_by: mah
creation_date: 2010-09-15T01:42:09Z

[Term]
id: GO:2000108
name: positive regulation of leukocyte apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis]
synonym: "positive regulation of leukocyte apoptosis" NARROW []
is_a: GO:0043065 ! positive regulation of apoptotic process
is_a: GO:2000106 ! regulation of leukocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0071887 ! leukocyte apoptotic process
relationship: positively_regulates GO:0071887 ! leukocyte apoptotic process
created_by: mah
creation_date: 2010-09-15T01:42:12Z

[Term]
id: GO:2000114
name: regulation of establishment of cell polarity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of establishment of cell polarity." [GOC:dph]
synonym: "regulation of bud site selection/establishment of cell polarity" RELATED [GOC:obol]
synonym: "regulation of cell polarization" EXACT [GOC:obol]
is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030010 ! establishment of cell polarity
relationship: regulates GO:0030010 ! establishment of cell polarity
created_by: dph
creation_date: 2010-09-16T01:22:36Z

[Term]
id: GO:2000136
name: regulation of cell proliferation involved in heart morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061323 ! cell proliferation involved in heart morphogenesis
relationship: regulates GO:0061323 ! cell proliferation involved in heart morphogenesis
created_by: dph
creation_date: 2010-09-29T12:43:53Z

[Term]
id: GO:2000137
name: negative regulation of cell proliferation involved in heart morphogenesis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis
relationship: negatively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis
created_by: dph
creation_date: 2010-09-29T12:43:55Z

[Term]
id: GO:2000138
name: positive regulation of cell proliferation involved in heart morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis
relationship: positively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis
created_by: dph
creation_date: 2010-09-29T12:43:57Z

[Term]
id: GO:2000145
name: regulation of cell motility
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell motility." [GOC:mah]
synonym: "regulation of cell locomotion" EXACT [GOC:obol]
synonym: "regulation of cell movement" RELATED [GOC:obol]
synonym: "regulation of movement of a cell" EXACT [GOC:obol]
is_a: GO:0040012 ! regulation of locomotion
is_a: GO:0050794 ! regulation of cellular process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048870 ! cell motility
relationship: regulates GO:0048870 ! cell motility
created_by: mah
creation_date: 2010-10-01T09:41:21Z

[Term]
id: GO:2000146
name: negative regulation of cell motility
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility." [GOC:mah]
synonym: "negative regulation of cell locomotion" EXACT [GOC:obol]
synonym: "negative regulation of cell movement" RELATED [GOC:obol]
synonym: "negative regulation of movement of a cell" EXACT [GOC:obol]
is_a: GO:0040013 ! negative regulation of locomotion
is_a: GO:0048523 ! negative regulation of cellular process
is_a: GO:2000145 ! regulation of cell motility
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048870 ! cell motility
relationship: negatively_regulates GO:0048870 ! cell motility
created_by: mah
creation_date: 2010-10-01T09:41:26Z

[Term]
id: GO:2000147
name: positive regulation of cell motility
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell motility." [GOC:mah]
synonym: "positive regulation of cell locomotion" EXACT [GOC:obol]
synonym: "positive regulation of cell movement" RELATED [GOC:obol]
synonym: "positive regulation of movement of a cell" EXACT [GOC:obol]
is_a: GO:0040017 ! positive regulation of locomotion
is_a: GO:0048522 ! positive regulation of cellular process
is_a: GO:2000145 ! regulation of cell motility
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048870 ! cell motility
relationship: positively_regulates GO:0048870 ! cell motility
created_by: mah
creation_date: 2010-10-01T09:41:30Z

[Term]
id: GO:2000155
name: positive regulation of cilium-dependent cell motility
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl]
synonym: "positive regulation of ciliary cell motility" RELATED []
is_a: GO:1902019 ! regulation of cilium-dependent cell motility
is_a: GO:2000147 ! positive regulation of cell motility
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060285 ! cilium-dependent cell motility
relationship: positively_regulates GO:0060285 ! cilium-dependent cell motility
created_by: mah
creation_date: 2010-10-04T12:41:05Z

[Term]
id: GO:2000172
name: regulation of branching morphogenesis of a nerve
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF]
is_a: GO:0060688 ! regulation of morphogenesis of a branching structure
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048755 ! branching morphogenesis of a nerve
relationship: regulates GO:0048755 ! branching morphogenesis of a nerve
created_by: rl
creation_date: 2010-10-07T12:07:54Z

[Term]
id: GO:2000173
name: negative regulation of branching morphogenesis of a nerve
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048755 ! branching morphogenesis of a nerve
relationship: negatively_regulates GO:0048755 ! branching morphogenesis of a nerve
created_by: rl
creation_date: 2010-10-07T12:07:56Z

[Term]
id: GO:2000174
name: regulation of pro-T cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF]
synonym: "regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol]
is_a: GO:0045580 ! regulation of T cell differentiation
is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002572 ! pro-T cell differentiation
relationship: regulates GO:0002572 ! pro-T cell differentiation
created_by: mah
creation_date: 2010-10-11T10:24:30Z

[Term]
id: GO:2000175
name: negative regulation of pro-T cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF]
synonym: "negative regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol]
is_a: GO:0045581 ! negative regulation of T cell differentiation
is_a: GO:1905457 ! negative regulation of lymphoid progenitor cell differentiation
is_a: GO:2000174 ! regulation of pro-T cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002572 ! pro-T cell differentiation
relationship: negatively_regulates GO:0002572 ! pro-T cell differentiation
created_by: mah
creation_date: 2010-10-11T10:24:33Z

[Term]
id: GO:2000176
name: positive regulation of pro-T cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF]
synonym: "positive regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol]
is_a: GO:0045582 ! positive regulation of T cell differentiation
is_a: GO:1905458 ! positive regulation of lymphoid progenitor cell differentiation
is_a: GO:2000174 ! regulation of pro-T cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002572 ! pro-T cell differentiation
relationship: positively_regulates GO:0002572 ! pro-T cell differentiation
created_by: mah
creation_date: 2010-10-11T10:24:35Z

[Term]
id: GO:2000177
name: regulation of neural precursor cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061351 ! neural precursor cell proliferation
relationship: regulates GO:0061351 ! neural precursor cell proliferation
created_by: dph
creation_date: 2010-10-13T12:40:41Z

[Term]
id: GO:2000178
name: negative regulation of neural precursor cell proliferation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:2000177 ! regulation of neural precursor cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061351 ! neural precursor cell proliferation
relationship: negatively_regulates GO:0061351 ! neural precursor cell proliferation
created_by: dph
creation_date: 2010-10-13T12:40:43Z

[Term]
id: GO:2000179
name: positive regulation of neural precursor cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:2000177 ! regulation of neural precursor cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061351 ! neural precursor cell proliferation
relationship: positively_regulates GO:0061351 ! neural precursor cell proliferation
created_by: dph
creation_date: 2010-10-13T12:40:45Z

[Term]
id: GO:2000181
name: negative regulation of blood vessel morphogenesis
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis." [GOC:dph, GOC:yaf]
is_a: GO:0022603 ! regulation of anatomical structure morphogenesis
is_a: GO:1901343 ! negative regulation of vasculature development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048514 ! blood vessel morphogenesis
relationship: negatively_regulates GO:0048514 ! blood vessel morphogenesis
created_by: dph
creation_date: 2010-10-13T12:46:31Z

[Term]
id: GO:2000185
name: regulation of phosphate transmembrane transport
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol]
synonym: "regulation of phosphate membrane transport" EXACT []
is_a: GO:0010966 ! regulation of phosphate transport
is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035435 ! phosphate ion transmembrane transport
relationship: regulates GO:0035435 ! phosphate ion transmembrane transport
created_by: vw
creation_date: 2010-10-15T11:33:04Z

[Term]
id: GO:2000186
name: negative regulation of phosphate transmembrane transport
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol]
synonym: "negative regulation of phosphate membrane transport" EXACT []
is_a: GO:1903796 ! negative regulation of inorganic anion transmembrane transport
is_a: GO:2000185 ! regulation of phosphate transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035435 ! phosphate ion transmembrane transport
relationship: negatively_regulates GO:0035435 ! phosphate ion transmembrane transport
created_by: vw
creation_date: 2010-10-15T11:33:08Z

[Term]
id: GO:2000187
name: positive regulation of phosphate transmembrane transport
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol]
synonym: "positive regulation of phosphate membrane transport" EXACT []
is_a: GO:1903797 ! positive regulation of inorganic anion transmembrane transport
is_a: GO:2000185 ! regulation of phosphate transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035435 ! phosphate ion transmembrane transport
relationship: positively_regulates GO:0035435 ! phosphate ion transmembrane transport
created_by: vw
creation_date: 2010-10-15T11:33:10Z

[Term]
id: GO:2000194
name: regulation of female gonad development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of female gonad development." [GOC:obol]
synonym: "regulation of ovarian development" EXACT [GOC:obol]
synonym: "regulation of ovary development" EXACT [GOC:obol]
is_a: GO:1905939 ! regulation of gonad development
is_a: GO:2000026 ! regulation of multicellular organismal development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008585 ! female gonad development
relationship: regulates GO:0008585 ! female gonad development
created_by: yaf
creation_date: 2010-10-19T10:45:34Z

[Term]
id: GO:2000195
name: negative regulation of female gonad development
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development." [GOC:obol]
synonym: "negative regulation of ovarian development" EXACT [GOC:obol]
synonym: "negative regulation of ovary development" EXACT [GOC:obol]
is_a: GO:1905940 ! negative regulation of gonad development
is_a: GO:2000194 ! regulation of female gonad development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008585 ! female gonad development
relationship: negatively_regulates GO:0008585 ! female gonad development
created_by: yaf
creation_date: 2010-10-19T10:45:38Z

[Term]
id: GO:2000196
name: positive regulation of female gonad development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of female gonad development." [GOC:obol]
synonym: "positive regulation of ovarian development" EXACT [GOC:obol]
synonym: "positive regulation of ovary development" EXACT [GOC:obol]
is_a: GO:1905941 ! positive regulation of gonad development
is_a: GO:2000194 ! regulation of female gonad development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008585 ! female gonad development
relationship: positively_regulates GO:0008585 ! female gonad development
created_by: yaf
creation_date: 2010-10-19T10:45:41Z

[Term]
id: GO:2000226
name: regulation of pancreatic A cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah]
synonym: "regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol]
is_a: GO:0030856 ! regulation of epithelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003310 ! pancreatic A cell differentiation
relationship: regulates GO:0003310 ! pancreatic A cell differentiation
created_by: mah
creation_date: 2010-11-09T03:43:37Z

[Term]
id: GO:2000227
name: negative regulation of pancreatic A cell differentiation
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah]
synonym: "negative regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol]
is_a: GO:0030857 ! negative regulation of epithelial cell differentiation
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:2000226 ! regulation of pancreatic A cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0003310 ! pancreatic A cell differentiation
relationship: negatively_regulates GO:0003310 ! pancreatic A cell differentiation
created_by: mah
creation_date: 2010-11-09T03:43:40Z

[Term]
id: GO:2000228
name: positive regulation of pancreatic A cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah]
synonym: "positive regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol]
is_a: GO:0030858 ! positive regulation of epithelial cell differentiation
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:2000226 ! regulation of pancreatic A cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0003310 ! pancreatic A cell differentiation
relationship: positively_regulates GO:0003310 ! pancreatic A cell differentiation
created_by: mah
creation_date: 2010-11-09T03:43:42Z

[Term]
id: GO:2000241
name: regulation of reproductive process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of reproductive process." [GOC:mah]
is_a: GO:0050789 ! regulation of biological process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0022414 ! reproductive process
relationship: regulates GO:0022414 ! reproductive process
created_by: mah
creation_date: 2010-11-10T02:44:02Z

[Term]
id: GO:2000242
name: negative regulation of reproductive process
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process." [GOC:mah]
is_a: GO:0048519 ! negative regulation of biological process
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0022414 ! reproductive process
relationship: negatively_regulates GO:0022414 ! reproductive process
created_by: mah
creation_date: 2010-11-10T02:44:05Z

[Term]
id: GO:2000243
name: positive regulation of reproductive process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of reproductive process." [GOC:mah]
is_a: GO:0048518 ! positive regulation of biological process
is_a: GO:2000241 ! regulation of reproductive process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0022414 ! reproductive process
relationship: positively_regulates GO:0022414 ! reproductive process
created_by: mah
creation_date: 2010-11-10T02:44:08Z

[Term]
id: GO:2000248
name: negative regulation of establishment or maintenance of neuroblast polarity
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity." [GOC:obol]
synonym: "negative regulation of establishment and/or maintenance of neuroblast cell polarity" EXACT [GOC:obol]
is_a: GO:0010454 ! negative regulation of cell fate commitment
is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity
is_a: GO:0045769 ! negative regulation of asymmetric cell division
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0045196 ! establishment or maintenance of neuroblast polarity
relationship: negatively_regulates GO:0045196 ! establishment or maintenance of neuroblast polarity
created_by: vw
creation_date: 2010-11-11T11:40:34Z

[Term]
id: GO:2000254
name: regulation of male germ cell proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of male germ cell proliferation." [GOC:obol]
is_a: GO:1905936 ! regulation of germ cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0002176 ! male germ cell proliferation
relationship: regulates GO:0002176 ! male germ cell proliferation
created_by: dph
creation_date: 2010-11-18T09:29:44Z

[Term]
id: GO:2000255
name: negative regulation of male germ cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation." [GOC:obol]
is_a: GO:1905937 ! negative regulation of germ cell proliferation
is_a: GO:2000254 ! regulation of male germ cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0002176 ! male germ cell proliferation
relationship: negatively_regulates GO:0002176 ! male germ cell proliferation
created_by: dph
creation_date: 2010-11-18T09:29:47Z

[Term]
id: GO:2000256
name: positive regulation of male germ cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of male germ cell proliferation." [GOC:obol]
is_a: GO:1905938 ! positive regulation of germ cell proliferation
is_a: GO:2000254 ! regulation of male germ cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0002176 ! male germ cell proliferation
relationship: positively_regulates GO:0002176 ! male germ cell proliferation
created_by: dph
creation_date: 2010-11-18T09:29:50Z

[Term]
id: GO:2000269
name: regulation of fibroblast apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf]
synonym: "regulation of fibroblast apoptosis" NARROW []
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0044346 ! fibroblast apoptotic process
relationship: regulates GO:0044346 ! fibroblast apoptotic process
created_by: jl
creation_date: 2010-11-23T01:07:23Z

[Term]
id: GO:2000270
name: negative regulation of fibroblast apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf]
synonym: "negative regulation of fibroblast apoptosis" NARROW []
is_a: GO:0043066 ! negative regulation of apoptotic process
is_a: GO:2000269 ! regulation of fibroblast apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0044346 ! fibroblast apoptotic process
relationship: negatively_regulates GO:0044346 ! fibroblast apoptotic process
created_by: jl
creation_date: 2010-11-23T01:07:27Z

[Term]
id: GO:2000271
name: positive regulation of fibroblast apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf]
synonym: "positive regulation of fibroblast apoptosis" NARROW []
is_a: GO:0043065 ! positive regulation of apoptotic process
is_a: GO:2000269 ! regulation of fibroblast apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0044346 ! fibroblast apoptotic process
relationship: positively_regulates GO:0044346 ! fibroblast apoptotic process
created_by: jl
creation_date: 2010-11-23T01:07:29Z

[Term]
id: GO:2000278
name: regulation of DNA biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of DNA biosynthetic process." [GOC:obol]
synonym: "regulation of DNA anabolism" EXACT [GOC:obol]
synonym: "regulation of DNA biosynthesis" EXACT [GOC:obol]
synonym: "regulation of DNA formation" EXACT [GOC:obol]
synonym: "regulation of DNA synthesis" EXACT [GOC:obol]
is_a: GO:0010556 ! regulation of macromolecule biosynthetic process
is_a: GO:0051052 ! regulation of DNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0071897 ! DNA biosynthetic process
relationship: regulates GO:0071897 ! DNA biosynthetic process
created_by: yaf
creation_date: 2010-12-08T04:48:15Z

[Term]
id: GO:2000279
name: negative regulation of DNA biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process." [GOC:obol]
synonym: "negative regulation of DNA anabolism" EXACT [GOC:obol]
synonym: "negative regulation of DNA biosynthesis" EXACT [GOC:obol]
synonym: "negative regulation of DNA formation" EXACT [GOC:obol]
synonym: "negative regulation of DNA synthesis" EXACT [GOC:obol]
is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process
is_a: GO:0051053 ! negative regulation of DNA metabolic process
is_a: GO:2000278 ! regulation of DNA biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0071897 ! DNA biosynthetic process
relationship: negatively_regulates GO:0071897 ! DNA biosynthetic process
created_by: yaf
creation_date: 2010-12-08T04:48:20Z

[Term]
id: GO:2000282
name: regulation of cellular amino acid biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol]
synonym: "regulation of amino acid biosynthetic process" EXACT [GOC:obol]
synonym: "regulation of cellular amino acid anabolism" EXACT [GOC:obol]
synonym: "regulation of cellular amino acid biosynthesis" EXACT [GOC:obol]
synonym: "regulation of cellular amino acid formation" EXACT [GOC:obol]
synonym: "regulation of cellular amino acid synthesis" EXACT [GOC:obol]
is_a: GO:0031326 ! regulation of cellular biosynthetic process
is_a: GO:0051171 ! regulation of nitrogen compound metabolic process
is_a: GO:0062012 ! regulation of small molecule metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0008652 ! amino acid biosynthetic process
relationship: regulates GO:0008652 ! amino acid biosynthetic process
created_by: vw
creation_date: 2010-12-10T11:54:19Z

[Term]
id: GO:2000283
name: negative regulation of amino acid biosynthetic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process." [GOC:obol]
synonym: "negative regulation of amino acid anabolism" EXACT [GOC:obol]
synonym: "negative regulation of amino acid biosynthesis" EXACT [GOC:obol]
synonym: "negative regulation of amino acid formation" EXACT [GOC:obol]
synonym: "negative regulation of amino acid synthesis" EXACT [GOC:obol]
synonym: "negative regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol]
is_a: GO:0031327 ! negative regulation of cellular biosynthetic process
is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process
is_a: GO:0062014 ! negative regulation of small molecule metabolic process
is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0008652 ! amino acid biosynthetic process
relationship: negatively_regulates GO:0008652 ! amino acid biosynthetic process
created_by: vw
creation_date: 2010-12-10T11:54:23Z

[Term]
id: GO:2000284
name: positive regulation of amino acid biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol]
synonym: "positive regulation of amino acid anabolism" EXACT [GOC:obol]
synonym: "positive regulation of amino acid biosynthesis" EXACT [GOC:obol]
synonym: "positive regulation of amino acid formation" EXACT [GOC:obol]
synonym: "positive regulation of amino acid synthesis" EXACT [GOC:obol]
synonym: "positive regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol]
is_a: GO:0031328 ! positive regulation of cellular biosynthetic process
is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process
is_a: GO:0062013 ! positive regulation of small molecule metabolic process
is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0008652 ! amino acid biosynthetic process
relationship: positively_regulates GO:0008652 ! amino acid biosynthetic process
created_by: vw
creation_date: 2010-12-10T11:54:27Z

[Term]
id: GO:2000287
name: positive regulation of myotome development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of myotome development." [GOC:BHF]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:2000290 ! regulation of myotome development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061055 ! myotome development
relationship: positively_regulates GO:0061055 ! myotome development
created_by: rl
creation_date: 2010-12-16T05:17:15Z

[Term]
id: GO:2000288
name: positive regulation of myoblast proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of myoblast proliferation." [GOC:BHF]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:2000291 ! regulation of myoblast proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051450 ! myoblast proliferation
relationship: positively_regulates GO:0051450 ! myoblast proliferation
created_by: rl
creation_date: 2010-12-16T05:20:52Z

[Term]
id: GO:2000290
name: regulation of myotome development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of myotome development." [GOC:mah]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061055 ! myotome development
relationship: regulates GO:0061055 ! myotome development
created_by: mah
creation_date: 2010-12-20T10:22:05Z

[Term]
id: GO:2000291
name: regulation of myoblast proliferation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of myoblast proliferation." [GOC:mah]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0051450 ! myoblast proliferation
relationship: regulates GO:0051450 ! myoblast proliferation
created_by: mah
creation_date: 2010-12-20T10:34:26Z

[Term]
id: GO:2000292
name: regulation of defecation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of defecation." [GOC:obol]
is_a: GO:0044058 ! regulation of digestive system process
is_a: GO:0044062 ! regulation of excretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0030421 ! defecation
relationship: regulates GO:0030421 ! defecation
created_by: bf
creation_date: 2010-12-21T09:23:08Z

[Term]
id: GO:2000293
name: negative regulation of defecation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of defecation." [GOC:obol]
is_a: GO:0051048 ! negative regulation of secretion
is_a: GO:0060457 ! negative regulation of digestive system process
is_a: GO:2000292 ! regulation of defecation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0030421 ! defecation
relationship: negatively_regulates GO:0030421 ! defecation
created_by: bf
creation_date: 2010-12-21T09:23:13Z

[Term]
id: GO:2000294
name: positive regulation of defecation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of defecation." [GOC:obol]
is_a: GO:0051047 ! positive regulation of secretion
is_a: GO:0060456 ! positive regulation of digestive system process
is_a: GO:2000292 ! regulation of defecation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0030421 ! defecation
relationship: positively_regulates GO:0030421 ! defecation
created_by: bf
creation_date: 2010-12-21T09:23:16Z

[Term]
id: GO:2000351
name: regulation of endothelial cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis]
synonym: "regulation of apoptosis of endothelial cells" EXACT [GOC:obol]
synonym: "regulation of endothelial cell apoptosis" NARROW []
synonym: "regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol]
synonym: "regulation of killing of endothelial cells" EXACT [GOC:obol]
synonym: "regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol]
synonym: "regulation of programmed cell death, endothelial cells" EXACT [GOC:obol]
is_a: GO:1904035 ! regulation of epithelial cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072577 ! endothelial cell apoptotic process
relationship: regulates GO:0072577 ! endothelial cell apoptotic process
created_by: mah
creation_date: 2011-02-03T10:43:16Z

[Term]
id: GO:2000352
name: negative regulation of endothelial cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis]
synonym: "negative regulation of apoptosis of endothelial cells" EXACT [GOC:obol]
synonym: "negative regulation of endothelial cell apoptosis" NARROW []
synonym: "negative regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol]
synonym: "negative regulation of killing of endothelial cells" EXACT [GOC:obol]
synonym: "negative regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol]
synonym: "negative regulation of programmed cell death, endothelial cells" EXACT [GOC:obol]
is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process
is_a: GO:2000351 ! regulation of endothelial cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072577 ! endothelial cell apoptotic process
relationship: negatively_regulates GO:0072577 ! endothelial cell apoptotic process
created_by: mah
creation_date: 2011-02-03T10:43:20Z

[Term]
id: GO:2000353
name: positive regulation of endothelial cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis]
synonym: "positive regulation of apoptosis of endothelial cells" EXACT [GOC:obol]
synonym: "positive regulation of endothelial cell apoptosis" NARROW []
synonym: "positive regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol]
synonym: "positive regulation of killing of endothelial cells" EXACT [GOC:obol]
synonym: "positive regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol]
synonym: "positive regulation of programmed cell death, endothelial cells" EXACT [GOC:obol]
is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process
is_a: GO:2000351 ! regulation of endothelial cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072577 ! endothelial cell apoptotic process
relationship: positively_regulates GO:0072577 ! endothelial cell apoptotic process
created_by: mah
creation_date: 2011-02-03T10:43:23Z

[Term]
id: GO:2000374
name: regulation of oxygen metabolic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of oxygen metabolic process." [GOC:mah]
synonym: "regulation of diatomic oxygen metabolic process" EXACT [GOC:obol]
synonym: "regulation of oxygen metabolism" EXACT [GOC:obol]
is_a: GO:0031323 ! regulation of cellular metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072592 ! oxygen metabolic process
relationship: regulates GO:0072592 ! oxygen metabolic process
created_by: mah
creation_date: 2011-02-11T02:03:32Z

[Term]
id: GO:2000375
name: negative regulation of oxygen metabolic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process." [GOC:mah]
synonym: "negative regulation of diatomic oxygen metabolic process" EXACT [GOC:obol]
synonym: "negative regulation of oxygen metabolism" EXACT [GOC:obol]
is_a: GO:0031324 ! negative regulation of cellular metabolic process
is_a: GO:2000374 ! regulation of oxygen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072592 ! oxygen metabolic process
relationship: negatively_regulates GO:0072592 ! oxygen metabolic process
created_by: mah
creation_date: 2011-02-11T02:03:44Z

[Term]
id: GO:2000376
name: positive regulation of oxygen metabolic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of oxygen metabolic process." [GOC:mah]
synonym: "positive regulation of diatomic oxygen metabolic process" EXACT [GOC:obol]
synonym: "positive regulation of oxygen metabolism" EXACT [GOC:obol]
is_a: GO:0031325 ! positive regulation of cellular metabolic process
is_a: GO:2000374 ! regulation of oxygen metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072592 ! oxygen metabolic process
relationship: positively_regulates GO:0072592 ! oxygen metabolic process
created_by: mah
creation_date: 2011-02-11T02:03:52Z

[Term]
id: GO:2000380
name: regulation of mesoderm development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesoderm development." [GOC:BHF]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007498 ! mesoderm development
relationship: regulates GO:0007498 ! mesoderm development
created_by: vk
creation_date: 2011-02-15T03:09:46Z

[Term]
id: GO:2000381
name: negative regulation of mesoderm development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development." [GOC:BHF]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:2000380 ! regulation of mesoderm development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007498 ! mesoderm development
relationship: negatively_regulates GO:0007498 ! mesoderm development
created_by: vk
creation_date: 2011-02-15T03:10:02Z

[Term]
id: GO:2000382
name: positive regulation of mesoderm development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesoderm development." [GOC:BHF]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:2000380 ! regulation of mesoderm development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007498 ! mesoderm development
relationship: positively_regulates GO:0007498 ! mesoderm development
created_by: vk
creation_date: 2011-02-15T03:10:12Z

[Term]
id: GO:2000383
name: regulation of ectoderm development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of ectoderm development." [GOC:BHF]
is_a: GO:0050793 ! regulation of developmental process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0007398 ! ectoderm development
relationship: regulates GO:0007398 ! ectoderm development
created_by: vk
creation_date: 2011-02-15T03:17:10Z

[Term]
id: GO:2000384
name: negative regulation of ectoderm development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development." [GOC:BHF]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:2000383 ! regulation of ectoderm development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007398 ! ectoderm development
relationship: negatively_regulates GO:0007398 ! ectoderm development
created_by: vk
creation_date: 2011-02-15T03:17:27Z

[Term]
id: GO:2000385
name: positive regulation of ectoderm development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of ectoderm development." [GOC:BHF]
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:2000383 ! regulation of ectoderm development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007398 ! ectoderm development
relationship: positively_regulates GO:0007398 ! ectoderm development
created_by: vk
creation_date: 2011-02-15T03:17:39Z

[Term]
id: GO:2000401
name: regulation of lymphocyte migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of lymphocyte migration." [GOC:mah]
is_a: GO:0071675 ! regulation of mononuclear cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072676 ! lymphocyte migration
relationship: regulates GO:0072676 ! lymphocyte migration
created_by: mah
creation_date: 2011-02-23T10:45:19Z

[Term]
id: GO:2000402
name: negative regulation of lymphocyte migration
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration." [GOC:mah]
is_a: GO:0071676 ! negative regulation of mononuclear cell migration
is_a: GO:2000401 ! regulation of lymphocyte migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072676 ! lymphocyte migration
relationship: negatively_regulates GO:0072676 ! lymphocyte migration
created_by: mah
creation_date: 2011-02-23T10:45:47Z

[Term]
id: GO:2000403
name: positive regulation of lymphocyte migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of lymphocyte migration." [GOC:mah]
is_a: GO:0071677 ! positive regulation of mononuclear cell migration
is_a: GO:2000401 ! regulation of lymphocyte migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072676 ! lymphocyte migration
relationship: positively_regulates GO:0072676 ! lymphocyte migration
created_by: mah
creation_date: 2011-02-23T10:46:06Z

[Term]
id: GO:2000404
name: regulation of T cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of T cell migration." [GOC:mah]
synonym: "regulation of T lymphocyte migration" EXACT [GOC:obol]
synonym: "regulation of T-cell migration" EXACT [GOC:obol]
synonym: "regulation of T-lymphocyte migration" EXACT [GOC:obol]
is_a: GO:2000401 ! regulation of lymphocyte migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0072678 ! T cell migration
relationship: regulates GO:0072678 ! T cell migration
created_by: mah
creation_date: 2011-02-23T10:48:24Z

[Term]
id: GO:2000405
name: negative regulation of T cell migration
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration." [GOC:mah]
synonym: "negative regulation of T lymphocyte migration" EXACT [GOC:obol]
synonym: "negative regulation of T-cell migration" EXACT [GOC:obol]
synonym: "negative regulation of T-lymphocyte migration" EXACT [GOC:obol]
is_a: GO:2000402 ! negative regulation of lymphocyte migration
is_a: GO:2000404 ! regulation of T cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072678 ! T cell migration
relationship: negatively_regulates GO:0072678 ! T cell migration
created_by: mah
creation_date: 2011-02-23T10:48:52Z

[Term]
id: GO:2000406
name: positive regulation of T cell migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of T cell migration." [GOC:mah]
synonym: "positive regulation of T lymphocyte migration" EXACT [GOC:obol]
synonym: "positive regulation of T-cell migration" EXACT [GOC:obol]
synonym: "positive regulation of T-lymphocyte migration" EXACT [GOC:obol]
is_a: GO:2000403 ! positive regulation of lymphocyte migration
is_a: GO:2000404 ! regulation of T cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072678 ! T cell migration
relationship: positively_regulates GO:0072678 ! T cell migration
created_by: mah
creation_date: 2011-02-23T10:49:12Z

[Term]
id: GO:2000471
name: regulation of hematopoietic stem cell migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol]
synonym: "regulation of hemopoietic stem cell migration" EXACT [GOC:obol]
is_a: GO:0030334 ! regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035701 ! hematopoietic stem cell migration
relationship: regulates GO:0035701 ! hematopoietic stem cell migration
created_by: bf
creation_date: 2011-03-09T09:34:08Z

[Term]
id: GO:2000472
name: negative regulation of hematopoietic stem cell migration
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol]
synonym: "negative regulation of hemopoietic stem cell migration" EXACT [GOC:obol]
is_a: GO:0030336 ! negative regulation of cell migration
is_a: GO:2000471 ! regulation of hematopoietic stem cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035701 ! hematopoietic stem cell migration
relationship: negatively_regulates GO:0035701 ! hematopoietic stem cell migration
created_by: bf
creation_date: 2011-03-09T09:34:54Z

[Term]
id: GO:2000473
name: positive regulation of hematopoietic stem cell migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol]
synonym: "positive regulation of hemopoietic stem cell migration" EXACT [GOC:obol]
is_a: GO:0030335 ! positive regulation of cell migration
is_a: GO:2000471 ! regulation of hematopoietic stem cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035701 ! hematopoietic stem cell migration
relationship: positively_regulates GO:0035701 ! hematopoietic stem cell migration
created_by: bf
creation_date: 2011-03-09T09:35:25Z

[Term]
id: GO:2000495
name: regulation of cell proliferation involved in compound eye morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol]
is_a: GO:0042127 ! regulation of cell population proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis
relationship: regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis
created_by: bf
creation_date: 2011-03-18T02:18:34Z

[Term]
id: GO:2000496
name: negative regulation of cell proliferation involved in compound eye morphogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis
relationship: negatively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis
created_by: bf
creation_date: 2011-03-18T02:19:22Z

[Term]
id: GO:2000497
name: positive regulation of cell proliferation involved in compound eye morphogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis
relationship: positively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis
created_by: bf
creation_date: 2011-03-18T02:19:54Z

[Term]
id: GO:2000542
name: negative regulation of gastrulation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation." [GOC:obol]
is_a: GO:0010470 ! regulation of gastrulation
is_a: GO:0045992 ! negative regulation of embryonic development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007369 ! gastrulation
relationship: negatively_regulates GO:0007369 ! gastrulation
created_by: yaf
creation_date: 2011-04-01T04:10:08Z

[Term]
id: GO:2000543
name: positive regulation of gastrulation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of gastrulation." [GOC:obol]
is_a: GO:0010470 ! regulation of gastrulation
is_a: GO:0040019 ! positive regulation of embryonic development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0007369 ! gastrulation
relationship: positively_regulates GO:0007369 ! gastrulation
created_by: yaf
creation_date: 2011-04-01T04:10:15Z

[Term]
id: GO:2000547
name: regulation of dendritic cell dendrite assembly
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol]
synonym: "regulation of dendritic extension" RELATED [GOC:obol]
is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097026 ! dendritic cell dendrite assembly
relationship: regulates GO:0097026 ! dendritic cell dendrite assembly
created_by: ebc
creation_date: 2011-04-03T07:21:55Z

[Term]
id: GO:2000548
name: negative regulation of dendritic cell dendrite assembly
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol]
synonym: "negative regulation of dendritic extension" RELATED [GOC:obol]
is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly
is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097026 ! dendritic cell dendrite assembly
relationship: negatively_regulates GO:0097026 ! dendritic cell dendrite assembly
created_by: ebc
creation_date: 2011-04-03T07:22:01Z

[Term]
id: GO:2000549
name: positive regulation of dendritic cell dendrite assembly
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol]
synonym: "positive regulation of dendritic extension" RELATED [GOC:obol]
is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly
is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097026 ! dendritic cell dendrite assembly
relationship: positively_regulates GO:0097026 ! dendritic cell dendrite assembly
created_by: ebc
creation_date: 2011-04-03T07:22:06Z

[Term]
id: GO:2000573
name: positive regulation of DNA biosynthetic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process." [GOC:obol]
synonym: "positive regulation of DNA anabolism" EXACT [GOC:obol]
synonym: "positive regulation of DNA biosynthesis" EXACT [GOC:obol]
synonym: "positive regulation of DNA formation" EXACT [GOC:obol]
synonym: "positive regulation of DNA synthesis" EXACT [GOC:obol]
is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process
is_a: GO:0051054 ! positive regulation of DNA metabolic process
is_a: GO:2000278 ! regulation of DNA biosynthetic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0071897 ! DNA biosynthetic process
relationship: positively_regulates GO:0071897 ! DNA biosynthetic process
created_by: yaf
creation_date: 2011-04-04T10:01:20Z

[Term]
id: GO:2000606
name: regulation of cell proliferation involved in mesonephros development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol]
is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0061209 ! cell proliferation involved in mesonephros development
relationship: regulates GO:0061209 ! cell proliferation involved in mesonephros development
created_by: yaf
creation_date: 2011-04-18T08:42:19Z

[Term]
id: GO:2000607
name: negative regulation of cell proliferation involved in mesonephros development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol]
is_a: GO:1901723 ! negative regulation of cell proliferation involved in kidney development
is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0061209 ! cell proliferation involved in mesonephros development
relationship: negatively_regulates GO:0061209 ! cell proliferation involved in mesonephros development
created_by: yaf
creation_date: 2011-04-18T08:42:23Z

[Term]
id: GO:2000608
name: positive regulation of cell proliferation involved in mesonephros development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol]
is_a: GO:1901724 ! positive regulation of cell proliferation involved in kidney development
is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0061209 ! cell proliferation involved in mesonephros development
relationship: positively_regulates GO:0061209 ! cell proliferation involved in mesonephros development
created_by: yaf
creation_date: 2011-04-18T08:42:25Z

[Term]
id: GO:2000647
name: negative regulation of stem cell proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation." [GOC:dph]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:0072091 ! regulation of stem cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0072089 ! stem cell proliferation
relationship: negatively_regulates GO:0072089 ! stem cell proliferation
created_by: dph
creation_date: 2011-04-27T01:04:22Z

[Term]
id: GO:2000648
name: positive regulation of stem cell proliferation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of stem cell proliferation." [GOC:dph]
is_a: GO:0008284 ! positive regulation of cell population proliferation
is_a: GO:0072091 ! regulation of stem cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072089 ! stem cell proliferation
relationship: positively_regulates GO:0072089 ! stem cell proliferation
created_by: dph
creation_date: 2011-04-27T01:04:25Z

[Term]
id: GO:2000649
name: regulation of sodium ion transmembrane transporter activity
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol]
subset: gocheck_do_not_annotate
synonym: "regulation of sodium transporter activity" EXACT [GOC:obol]
is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity
is_a: GO:1902305 ! regulation of sodium ion transmembrane transport
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0015081 ! sodium ion transmembrane transporter activity
relationship: regulates GO:0015081 ! sodium ion transmembrane transporter activity
created_by: yaf
creation_date: 2011-04-28T08:42:53Z

[Term]
id: GO:2000650
name: negative regulation of sodium ion transmembrane transporter activity
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol]
subset: gocheck_do_not_annotate
synonym: "negative regulation of sodium transporter activity" EXACT [GOC:obol]
is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity
is_a: GO:1902306 ! negative regulation of sodium ion transmembrane transport
is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0015081 ! sodium ion transmembrane transporter activity
relationship: negatively_regulates GO:0015081 ! sodium ion transmembrane transporter activity
created_by: yaf
creation_date: 2011-04-28T08:42:57Z

[Term]
id: GO:2000651
name: positive regulation of sodium ion transmembrane transporter activity
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol]
subset: gocheck_do_not_annotate
synonym: "positive regulation of sodium transporter activity" EXACT [GOC:obol]
is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity
is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport
is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0015081 ! sodium ion transmembrane transporter activity
relationship: positively_regulates GO:0015081 ! sodium ion transmembrane transporter activity
created_by: yaf
creation_date: 2011-04-28T08:43:00Z

[Term]
id: GO:2000668
name: regulation of dendritic cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "regulation of dendritic cell apoptosis" NARROW []
is_a: GO:2000106 ! regulation of leukocyte apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097048 ! dendritic cell apoptotic process
relationship: regulates GO:0097048 ! dendritic cell apoptotic process
created_by: pr
creation_date: 2011-05-09T07:34:16Z

[Term]
id: GO:2000669
name: negative regulation of dendritic cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "negative regulation of dendritic cell apoptosis" NARROW []
is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process
is_a: GO:2000668 ! regulation of dendritic cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097048 ! dendritic cell apoptotic process
relationship: negatively_regulates GO:0097048 ! dendritic cell apoptotic process
created_by: pr
creation_date: 2011-05-09T07:34:21Z

[Term]
id: GO:2000670
name: positive regulation of dendritic cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "positive regulation of dendritic cell apoptosis" NARROW []
is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process
is_a: GO:2000668 ! regulation of dendritic cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097048 ! dendritic cell apoptotic process
relationship: positively_regulates GO:0097048 ! dendritic cell apoptotic process
created_by: pr
creation_date: 2011-05-09T07:34:26Z

[Term]
id: GO:2000671
name: regulation of motor neuron apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "regulation of motoneuron apoptosis" EXACT [GOC:obol]
synonym: "regulation of motor neuron apoptosis" NARROW []
is_a: GO:0043523 ! regulation of neuron apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097049 ! motor neuron apoptotic process
relationship: regulates GO:0097049 ! motor neuron apoptotic process
created_by: pr
creation_date: 2011-05-09T10:56:17Z

[Term]
id: GO:2000672
name: negative regulation of motor neuron apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "negative regulation of motoneuron apoptosis" EXACT [GOC:obol]
synonym: "negative regulation of motor neuron apoptosis" NARROW []
is_a: GO:0043524 ! negative regulation of neuron apoptotic process
is_a: GO:2000671 ! regulation of motor neuron apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097049 ! motor neuron apoptotic process
relationship: negatively_regulates GO:0097049 ! motor neuron apoptotic process
created_by: pr
creation_date: 2011-05-09T10:56:21Z

[Term]
id: GO:2000673
name: positive regulation of motor neuron apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "positive regulation of motoneuron apoptosis" EXACT [GOC:obol]
synonym: "positive regulation of motor neuron apoptosis" NARROW []
is_a: GO:0043525 ! positive regulation of neuron apoptotic process
is_a: GO:2000671 ! regulation of motor neuron apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097049 ! motor neuron apoptotic process
relationship: positively_regulates GO:0097049 ! motor neuron apoptotic process
created_by: pr
creation_date: 2011-05-09T10:56:24Z

[Term]
id: GO:2000674
name: regulation of type B pancreatic cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "regulation of pancreatic B cell apoptosis" EXACT [GOC:obol]
synonym: "regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol]
synonym: "regulation of type B pancreatic cell apoptosis" NARROW []
is_a: GO:1904035 ! regulation of epithelial cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097050 ! type B pancreatic cell apoptotic process
relationship: regulates GO:0097050 ! type B pancreatic cell apoptotic process
created_by: pr
creation_date: 2011-05-09T11:51:09Z

[Term]
id: GO:2000675
name: negative regulation of type B pancreatic cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "negative regulation of pancreatic B cell apoptosis" EXACT [GOC:obol]
synonym: "negative regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol]
synonym: "negative regulation of type B pancreatic cell apoptosis" NARROW []
is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process
is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097050 ! type B pancreatic cell apoptotic process
relationship: negatively_regulates GO:0097050 ! type B pancreatic cell apoptotic process
created_by: pr
creation_date: 2011-05-09T11:51:12Z

[Term]
id: GO:2000676
name: positive regulation of type B pancreatic cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "positive regulation of pancreatic B cell apoptosis" EXACT [GOC:obol]
synonym: "positive regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol]
synonym: "positive regulation of type B pancreatic cell apoptosis" NARROW []
is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process
is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097050 ! type B pancreatic cell apoptotic process
relationship: positively_regulates GO:0097050 ! type B pancreatic cell apoptotic process
created_by: pr
creation_date: 2011-05-09T11:51:15Z

[Term]
id: GO:2000690
name: regulation of cardiac muscle cell myoblast differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol]
synonym: "regulation of cardiac myoblast differentiation" RELATED [GOC:obol]
synonym: "regulation of myocardial precursor cell differentiation" EXACT [GOC:obol]
is_a: GO:0045661 ! regulation of myoblast differentiation
is_a: GO:0051890 ! regulation of cardioblast differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060379 ! cardiac muscle cell myoblast differentiation
relationship: regulates GO:0060379 ! cardiac muscle cell myoblast differentiation
created_by: yaf
creation_date: 2011-05-25T09:08:01Z

[Term]
id: GO:2000691
name: negative regulation of cardiac muscle cell myoblast differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol]
synonym: "negative regulation of cardiac myoblast differentiation" RELATED [GOC:obol]
synonym: "negative regulation of myocardial precursor cell differentiation" EXACT [GOC:obol]
is_a: GO:0045662 ! negative regulation of myoblast differentiation
is_a: GO:0051892 ! negative regulation of cardioblast differentiation
is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation
relationship: negatively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation
created_by: yaf
creation_date: 2011-05-25T09:08:06Z

[Term]
id: GO:2000696
name: regulation of epithelial cell differentiation involved in kidney development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf]
is_a: GO:0030856 ! regulation of epithelial cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035850 ! epithelial cell differentiation involved in kidney development
relationship: regulates GO:0035850 ! epithelial cell differentiation involved in kidney development
created_by: bf
creation_date: 2011-05-16T04:23:52Z

[Term]
id: GO:2000697
name: negative regulation of epithelial cell differentiation involved in kidney development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf]
is_a: GO:0030857 ! negative regulation of epithelial cell differentiation
is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development
relationship: negatively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development
created_by: bf
creation_date: 2011-05-16T04:23:55Z

[Term]
id: GO:2000698
name: positive regulation of epithelial cell differentiation involved in kidney development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf]
is_a: GO:0030858 ! positive regulation of epithelial cell differentiation
is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development
relationship: positively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development
created_by: bf
creation_date: 2011-05-16T04:23:57Z

[Term]
id: GO:2000700
name: positive regulation of cardiac muscle cell myoblast differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol]
synonym: "positive regulation of cardiac myoblast differentiation" RELATED [GOC:obol]
synonym: "positive regulation of myocardial precursor cell differentiation" EXACT [GOC:obol]
is_a: GO:0045663 ! positive regulation of myoblast differentiation
is_a: GO:0051891 ! positive regulation of cardioblast differentiation
is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation
relationship: positively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation
created_by: yaf
creation_date: 2011-05-25T09:08:09Z

[Term]
id: GO:2000725
name: regulation of cardiac muscle cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF]
synonym: "regulation of cardiomyocyte differentiation" EXACT [GOC:obol]
synonym: "regulation of heart muscle cell differentiation" RELATED [GOC:obol]
is_a: GO:0051153 ! regulation of striated muscle cell differentiation
is_a: GO:1905207 ! regulation of cardiocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0055007 ! cardiac muscle cell differentiation
relationship: regulates GO:0055007 ! cardiac muscle cell differentiation
created_by: vk
creation_date: 2011-06-08T10:51:06Z

[Term]
id: GO:2000726
name: negative regulation of cardiac muscle cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF]
synonym: "negative regulation of cardiomyocyte differentiation" EXACT [GOC:obol]
synonym: "negative regulation of heart muscle cell differentiation" RELATED [GOC:obol]
is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation
is_a: GO:1905208 ! negative regulation of cardiocyte differentiation
is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0055007 ! cardiac muscle cell differentiation
relationship: negatively_regulates GO:0055007 ! cardiac muscle cell differentiation
created_by: vk
creation_date: 2011-06-08T10:51:11Z

[Term]
id: GO:2000727
name: positive regulation of cardiac muscle cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF]
synonym: "positive regulation of cardiomyocyte differentiation" EXACT [GOC:obol]
synonym: "positive regulation of heart muscle cell differentiation" RELATED [GOC:obol]
is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation
is_a: GO:1905209 ! positive regulation of cardiocyte differentiation
is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0055007 ! cardiac muscle cell differentiation
relationship: positively_regulates GO:0055007 ! cardiac muscle cell differentiation
created_by: vk
creation_date: 2011-06-08T10:51:15Z

[Term]
id: GO:2000729
name: positive regulation of mesenchymal cell proliferation involved in ureter development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development." [GOC:obol]
synonym: "positive regulation of ureter mesenchymal cell proliferation" RELATED [GOC:obol]
synonym: "positive regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:obol]
is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development
relationship: positively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development
created_by: yaf
creation_date: 2011-06-10T02:27:19Z

[Term]
id: GO:2000736
name: regulation of stem cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of stem cell differentiation." [GOC:obol]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0048863 ! stem cell differentiation
relationship: regulates GO:0048863 ! stem cell differentiation
created_by: yaf
creation_date: 2011-06-14T02:05:16Z

[Term]
id: GO:2000737
name: negative regulation of stem cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation." [GOC:obol]
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:2000736 ! regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0048863 ! stem cell differentiation
relationship: negatively_regulates GO:0048863 ! stem cell differentiation
created_by: yaf
creation_date: 2011-06-14T02:05:20Z

[Term]
id: GO:2000738
name: positive regulation of stem cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of stem cell differentiation." [GOC:obol]
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:2000736 ! regulation of stem cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0048863 ! stem cell differentiation
relationship: positively_regulates GO:0048863 ! stem cell differentiation
created_by: yaf
creation_date: 2011-06-14T02:05:23Z

[Term]
id: GO:2000768
name: positive regulation of nephron tubule epithelial cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:obol]
is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation
is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation
relationship: positively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation
created_by: yaf
creation_date: 2011-06-22T11:55:06Z

[Term]
id: GO:2000790
name: regulation of mesenchymal cell proliferation involved in lung development
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708]
is_a: GO:0010464 ! regulation of mesenchymal cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development
relationship: regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development
created_by: pr
creation_date: 2011-06-24T01:53:50Z

[Term]
id: GO:2000791
name: negative regulation of mesenchymal cell proliferation involved in lung development
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708]
is_a: GO:0051093 ! negative regulation of developmental process
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation
is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development
relationship: negatively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development
created_by: pr
creation_date: 2011-06-24T01:53:53Z

[Term]
id: GO:2000792
name: positive regulation of mesenchymal cell proliferation involved in lung development
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708]
is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation
is_a: GO:0051094 ! positive regulation of developmental process
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development
relationship: positively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development
created_by: pr
creation_date: 2011-06-24T01:53:56Z

[Term]
id: GO:2000794
name: regulation of epithelial cell proliferation involved in lung morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708]
is_a: GO:0050678 ! regulation of epithelial cell proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis
relationship: regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis
created_by: pr
creation_date: 2011-06-25T07:22:38Z

[Term]
id: GO:2000795
name: negative regulation of epithelial cell proliferation involved in lung morphogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708]
is_a: GO:0050680 ! negative regulation of epithelial cell proliferation
is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis
relationship: negatively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis
created_by: pr
creation_date: 2011-06-25T07:22:42Z

[Term]
id: GO:2000818
name: negative regulation of myoblast proliferation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation." [GOC:obol]
is_a: GO:0008285 ! negative regulation of cell population proliferation
is_a: GO:2000291 ! regulation of myoblast proliferation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051450 ! myoblast proliferation
relationship: negatively_regulates GO:0051450 ! myoblast proliferation
created_by: pr
creation_date: 2011-07-12T03:06:04Z

[Term]
id: GO:2000826
name: regulation of heart morphogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of heart morphogenesis." [GOC:BHF]
synonym: "regulation of cardiac morphogenesis" RELATED [GOC:obol]
is_a: GO:2000027 ! regulation of animal organ morphogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0003007 ! heart morphogenesis
relationship: regulates GO:0003007 ! heart morphogenesis
created_by: vk
creation_date: 2011-07-19T10:08:58Z

[Term]
id: GO:2000831
name: regulation of steroid hormone secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of steroid hormone secretion." [GOC:sl]
is_a: GO:0032368 ! regulation of lipid transport
is_a: GO:0044060 ! regulation of endocrine process
is_a: GO:0046883 ! regulation of hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035929 ! steroid hormone secretion
relationship: regulates GO:0035929 ! steroid hormone secretion
created_by: bf
creation_date: 2011-07-26T08:38:46Z

[Term]
id: GO:2000832
name: negative regulation of steroid hormone secretion
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion." [GOC:sl]
is_a: GO:0032369 ! negative regulation of lipid transport
is_a: GO:0046888 ! negative regulation of hormone secretion
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:2000831 ! regulation of steroid hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035929 ! steroid hormone secretion
relationship: negatively_regulates GO:0035929 ! steroid hormone secretion
created_by: bf
creation_date: 2011-07-26T08:38:50Z

[Term]
id: GO:2000833
name: positive regulation of steroid hormone secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of steroid hormone secretion." [GOC:sl]
is_a: GO:0032370 ! positive regulation of lipid transport
is_a: GO:0046887 ! positive regulation of hormone secretion
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:2000831 ! regulation of steroid hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035929 ! steroid hormone secretion
relationship: positively_regulates GO:0035929 ! steroid hormone secretion
created_by: bf
creation_date: 2011-07-26T08:38:51Z

[Term]
id: GO:2000834
name: regulation of androgen secretion
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of androgen secretion." [GOC:sl]
is_a: GO:2000831 ! regulation of steroid hormone secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035935 ! androgen secretion
relationship: regulates GO:0035935 ! androgen secretion
created_by: bf
creation_date: 2011-07-26T08:39:45Z

[Term]
id: GO:2000835
name: negative regulation of androgen secretion
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion." [GOC:sl]
is_a: GO:2000832 ! negative regulation of steroid hormone secretion
is_a: GO:2000834 ! regulation of androgen secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035935 ! androgen secretion
relationship: negatively_regulates GO:0035935 ! androgen secretion
created_by: bf
creation_date: 2011-07-26T08:39:48Z

[Term]
id: GO:2000836
name: positive regulation of androgen secretion
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of androgen secretion." [GOC:sl]
is_a: GO:2000833 ! positive regulation of steroid hormone secretion
is_a: GO:2000834 ! regulation of androgen secretion
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035935 ! androgen secretion
relationship: positively_regulates GO:0035935 ! androgen secretion
created_by: bf
creation_date: 2011-07-26T08:39:51Z

[Term]
id: GO:2001012
name: mesenchymal cell differentiation involved in renal system development
namespace: biological_process
def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf]
synonym: "mesenchymal cell differentiation involved in urinary system development" RELATED [GOC:obol]
synonym: "mesenchymal cell differentiation involved in urinary tract development" RELATED [GOC:obol]
is_a: GO:0048762 ! mesenchymal cell differentiation
intersection_of: GO:0048762 ! mesenchymal cell differentiation
intersection_of: part_of GO:0072001 ! renal system development
relationship: part_of GO:0072001 ! renal system development
created_by: yaf
creation_date: 2011-08-09T04:05:14Z

[Term]
id: GO:2001013
name: epithelial cell proliferation involved in renal tubule morphogenesis
namespace: biological_process
def: "Any epithelial cell proliferation that is involved in renal tubule morphogenesis." [GOC:obol]
is_a: GO:0050673 ! epithelial cell proliferation
intersection_of: GO:0050673 ! epithelial cell proliferation
intersection_of: part_of GO:0061333 ! renal tubule morphogenesis
relationship: part_of GO:0061333 ! renal tubule morphogenesis
created_by: yaf
creation_date: 2011-08-12T11:37:29Z

[Term]
id: GO:2001014
name: regulation of skeletal muscle cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0035914 ! skeletal muscle cell differentiation
relationship: regulates GO:0035914 ! skeletal muscle cell differentiation
created_by: yaf
creation_date: 2011-08-11T08:54:37Z

[Term]
id: GO:2001015
name: negative regulation of skeletal muscle cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol]
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0035914 ! skeletal muscle cell differentiation
relationship: negatively_regulates GO:0035914 ! skeletal muscle cell differentiation
created_by: yaf
creation_date: 2011-08-11T08:54:41Z

[Term]
id: GO:2001016
name: positive regulation of skeletal muscle cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol]
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0035914 ! skeletal muscle cell differentiation
relationship: positively_regulates GO:0035914 ! skeletal muscle cell differentiation
created_by: yaf
creation_date: 2011-08-11T08:54:44Z

[Term]
id: GO:2001053
name: regulation of mesenchymal cell apoptotic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "regulation of mesenchymal cell apoptosis" NARROW []
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097152 ! mesenchymal cell apoptotic process
relationship: regulates GO:0097152 ! mesenchymal cell apoptotic process
created_by: yaf
creation_date: 2011-09-08T02:49:59Z

[Term]
id: GO:2001054
name: negative regulation of mesenchymal cell apoptotic process
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "negative regulation of mesenchymal cell apoptosis" NARROW []
is_a: GO:0043066 ! negative regulation of apoptotic process
is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097152 ! mesenchymal cell apoptotic process
relationship: negatively_regulates GO:0097152 ! mesenchymal cell apoptotic process
created_by: yaf
creation_date: 2011-09-08T02:50:05Z

[Term]
id: GO:2001055
name: positive regulation of mesenchymal cell apoptotic process
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol]
synonym: "positive regulation of mesenchymal cell apoptosis" NARROW []
is_a: GO:0043065 ! positive regulation of apoptotic process
is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097152 ! mesenchymal cell apoptotic process
relationship: positively_regulates GO:0097152 ! mesenchymal cell apoptotic process
created_by: yaf
creation_date: 2011-09-08T02:50:09Z

[Term]
id: GO:2001141
name: regulation of RNA biosynthetic process
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." [GOC:dph]
synonym: "regulation of RNA anabolism" EXACT [GOC:obol]
synonym: "regulation of RNA biosynthesis" EXACT [GOC:obol]
synonym: "regulation of RNA formation" EXACT [GOC:obol]
synonym: "regulation of RNA synthesis" EXACT [GOC:obol]
is_a: GO:0010556 ! regulation of macromolecule biosynthetic process
is_a: GO:0051252 ! regulation of RNA metabolic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0032774 ! RNA biosynthetic process
relationship: regulates GO:0032774 ! RNA biosynthetic process
created_by: dph
creation_date: 2011-10-17T11:36:25Z

[Term]
id: GO:2001198
name: regulation of dendritic cell differentiation
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of dendritic cell differentiation." [GOC:obol]
is_a: GO:1902105 ! regulation of leukocyte differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097028 ! dendritic cell differentiation
relationship: regulates GO:0097028 ! dendritic cell differentiation
created_by: yaf
creation_date: 2011-11-04T02:01:27Z

[Term]
id: GO:2001199
name: negative regulation of dendritic cell differentiation
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation." [GOC:obol]
is_a: GO:1902106 ! negative regulation of leukocyte differentiation
is_a: GO:2001198 ! regulation of dendritic cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097028 ! dendritic cell differentiation
relationship: negatively_regulates GO:0097028 ! dendritic cell differentiation
created_by: yaf
creation_date: 2011-11-04T02:01:33Z

[Term]
id: GO:2001200
name: positive regulation of dendritic cell differentiation
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation." [GOC:obol]
is_a: GO:1902107 ! positive regulation of leukocyte differentiation
is_a: GO:2001198 ! regulation of dendritic cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097028 ! dendritic cell differentiation
relationship: positively_regulates GO:0097028 ! dendritic cell differentiation
created_by: yaf
creation_date: 2011-11-04T02:01:36Z

[Term]
id: GO:2001212
name: regulation of vasculogenesis
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of vasculogenesis." [GOC:obol]
synonym: "regulation of vascular morphogenesis" EXACT [GOC:obol]
is_a: GO:0045595 ! regulation of cell differentiation
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001570 ! vasculogenesis
relationship: regulates GO:0001570 ! vasculogenesis
created_by: yaf
creation_date: 2011-11-15T01:22:31Z

[Term]
id: GO:2001213
name: negative regulation of vasculogenesis
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis." [GOC:obol]
synonym: "negative regulation of vascular morphogenesis" EXACT [GOC:obol]
is_a: GO:0045596 ! negative regulation of cell differentiation
is_a: GO:2001212 ! regulation of vasculogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001570 ! vasculogenesis
relationship: negatively_regulates GO:0001570 ! vasculogenesis
created_by: yaf
creation_date: 2011-11-15T01:22:36Z

[Term]
id: GO:2001214
name: positive regulation of vasculogenesis
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of vasculogenesis." [GOC:obol]
synonym: "positive regulation of vascular morphogenesis" EXACT [GOC:obol]
is_a: GO:0045597 ! positive regulation of cell differentiation
is_a: GO:2001212 ! regulation of vasculogenesis
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001570 ! vasculogenesis
relationship: positively_regulates GO:0001570 ! vasculogenesis
created_by: yaf
creation_date: 2011-11-15T01:22:39Z

[Term]
id: GO:2001222
name: regulation of neuron migration
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of neuron migration." [GOC:obol]
synonym: "regulation of neuron chemotaxis" EXACT [GOC:obol]
synonym: "regulation of neuron guidance" RELATED [GOC:obol]
synonym: "regulation of neuronal migration" EXACT [GOC:obol]
is_a: GO:0030334 ! regulation of cell migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0001764 ! neuron migration
relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: regulates GO:0001764 ! neuron migration
created_by: kmv
creation_date: 2011-11-17T10:01:38Z

[Term]
id: GO:2001223
name: negative regulation of neuron migration
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration." [GOC:obol]
synonym: "negative regulation of neuron chemotaxis" EXACT [GOC:obol]
synonym: "negative regulation of neuron guidance" RELATED [GOC:obol]
synonym: "negative regulation of neuronal migration" EXACT [GOC:obol]
is_a: GO:0030336 ! negative regulation of cell migration
is_a: GO:2001222 ! regulation of neuron migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0001764 ! neuron migration
relationship: negatively_regulates GO:0001764 ! neuron migration
created_by: kmv
creation_date: 2011-11-17T10:01:45Z

[Term]
id: GO:2001224
name: positive regulation of neuron migration
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of neuron migration." [GOC:obol]
synonym: "positive regulation of neuron chemotaxis" EXACT [GOC:obol]
synonym: "positive regulation of neuron guidance" RELATED [GOC:obol]
synonym: "positive regulation of neuronal migration" EXACT [GOC:obol]
is_a: GO:0030335 ! positive regulation of cell migration
is_a: GO:2001222 ! regulation of neuron migration
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0001764 ! neuron migration
relationship: positively_regulates GO:0001764 ! neuron migration
created_by: kmv
creation_date: 2011-11-17T10:01:49Z

[Term]
id: GO:2001233
name: regulation of apoptotic signaling pathway
namespace: biological_process
def: "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis]
synonym: "regulation of apoptotic signalling pathway" EXACT [GOC:mah]
is_a: GO:0009966 ! regulation of signal transduction
is_a: GO:0042981 ! regulation of apoptotic process
intersection_of: GO:0065007 ! biological regulation
intersection_of: regulates GO:0097190 ! apoptotic signaling pathway
relationship: regulates GO:0097190 ! apoptotic signaling pathway
created_by: pr
creation_date: 2011-11-24T01:20:49Z

[Term]
id: GO:2001234
name: negative regulation of apoptotic signaling pathway
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis]
synonym: "negative regulation of apoptotic signalling pathway" EXACT [GOC:mah]
is_a: GO:0009968 ! negative regulation of signal transduction
is_a: GO:0043066 ! negative regulation of apoptotic process
is_a: GO:2001233 ! regulation of apoptotic signaling pathway
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0097190 ! apoptotic signaling pathway
relationship: negatively_regulates GO:0097190 ! apoptotic signaling pathway
created_by: pr
creation_date: 2011-11-24T01:20:54Z

[Term]
id: GO:2001235
name: positive regulation of apoptotic signaling pathway
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis]
synonym: "positive regulation of apoptotic signalling pathway" EXACT [GOC:mah]
is_a: GO:0009967 ! positive regulation of signal transduction
is_a: GO:0043065 ! positive regulation of apoptotic process
is_a: GO:2001233 ! regulation of apoptotic signaling pathway
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0097190 ! apoptotic signaling pathway
relationship: positively_regulates GO:0097190 ! apoptotic signaling pathway
created_by: pr
creation_date: 2011-11-24T01:20:58Z

[Term]
id: GO:2001251
name: negative regulation of chromosome organization
namespace: biological_process
def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization." [GOC:obol]
synonym: "negative regulation of chromosome organisation" EXACT [GOC:obol]
synonym: "negative regulation of chromosome organization and biogenesis" RELATED [GOC:obol]
synonym: "negative regulation of maintenance of genome integrity" RELATED [GOC:obol]
synonym: "negative regulation of nuclear genome maintenance" RELATED [GOC:obol]
is_a: GO:0010639 ! negative regulation of organelle organization
is_a: GO:0033044 ! regulation of chromosome organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0051276 ! chromosome organization
relationship: negatively_regulates GO:0051276 ! chromosome organization
created_by: yaf
creation_date: 2011-12-02T02:01:20Z

[Term]
id: GO:2001252
name: positive regulation of chromosome organization
namespace: biological_process
def: "Any process that activates or increases the frequency, rate or extent of chromosome organization." [GOC:obol]
synonym: "positive regulation of chromosome organisation" EXACT [GOC:obol]
synonym: "positive regulation of chromosome organization and biogenesis" RELATED [GOC:obol]
synonym: "positive regulation of maintenance of genome integrity" RELATED [GOC:obol]
synonym: "positive regulation of nuclear genome maintenance" RELATED [GOC:obol]
is_a: GO:0010638 ! positive regulation of organelle organization
is_a: GO:0033044 ! regulation of chromosome organization
intersection_of: GO:0065007 ! biological regulation
intersection_of: positively_regulates GO:0051276 ! chromosome organization
relationship: positively_regulates GO:0051276 ! chromosome organization
created_by: yaf
creation_date: 2011-12-02T02:01:26Z

[Term]
id: IAO:0000027
name: data item
def: "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements." []
is_a: IAO:0000030 ! information content entity
property_value: editor_note "2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers." xsd:string
property_value: editor_note "2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum." xsd:string
property_value: editor_note "2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym." xsd:string
property_value: editor_note "2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/" xsd:string
property_value: editor_note "JAR: datum     -- well, this will be very tricky to define, but maybe some \ninformation-like stuff that might be put into a computer and that is \nmeant, by someone, to denote and/or to be interpreted by some \nprocess... I would include lists, tables, sentences... I think I might \ndefer to Barry, or to Brian Cantwell Smith\n\nJAR: A data item is an approximately justified approximately true approximate belief" xsd:string
property_value: IAO:0000111 "data item" xsd:string
property_value: IAO:0000112 "Data items include counts of things, analyte concentrations, and statistical summaries." xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string
property_value: IAO:0000117 "PERSON: Chris Stoeckert" xsd:string
property_value: IAO:0000117 "PERSON: Jonathan Rees" xsd:string
property_value: IAO:0000118 "data" xsd:string

[Term]
id: IAO:0000028
name: symbol
def: "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity." []
is_a: IAO:0000030 ! information content entity
property_value: editor_note "20091104, MC: this needs work and will most probably change" xsd:string
property_value: editor_note "2014-03-31: We would like to have a deeper analysis of 'mark' and 'sign' in the future (see https://github.com/information-artifact-ontology/IAO/issues/154)." xsd:string
property_value: IAO:0000111 "symbol" xsd:string
property_value: IAO:0000112 "a serial number such as \"12324X\"" xsd:string
property_value: IAO:0000112 "a stop sign" xsd:string
property_value: IAO:0000112 "a written proper name such as \"OBI\"" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 "PERSON: James A. Overton" xsd:string
property_value: IAO:0000117 "PERSON: Jonathan Rees" xsd:string
property_value: IAO:0000119 "based on Oxford English Dictionary" xsd:string

[Term]
id: IAO:0000030
name: information content entity
def: "A generically dependent continuant that is about some thing." []
is_a: BFO:0000031 ! generically dependent continuant
relationship: IAO:0000136 BFO:0000001 ! is about entity
property_value: editor_note "2014-03-10: The use of \"thing\" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ)." xsd:string
property_value: editor_note "information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907).\n\nPrevious. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity." xsd:string
property_value: IAO:0000111 "information content entity" xsd:string
property_value: IAO:0000112 "Examples of information content entites include journal articles, data, graphical layouts, and graphs." xsd:string
property_value: IAO:0000114 IAO:0000122
property_value: IAO:0000117 "PERSON: Chris Stoeckert" xsd:string
property_value: IAO:0000119 "OBI_0000142" xsd:string

[Term]
id: IAO:0000078
name: curation status specification
def: "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." []
is_a: IAO:0000102 ! data about an ontology part
property_value: editor_note "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)" xsd:string
property_value: IAO:0000111 "curation status specification" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 "PERSON:Bill Bug" xsd:string
property_value: IAO:0000119 "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>" xsd:string
property_value: IAO:0000119 "OBI_0000266" xsd:string

[Term]
id: IAO:0000102
name: data about an ontology part
def: "Data about an ontology part is a data item about a part of an ontology, for example a term" []
is_a: IAO:0000027 ! data item
property_value: IAO:0000111 "data about an ontology part" xsd:string
property_value: IAO:0000117 "Person:Alan Ruttenberg" xsd:string

[Term]
id: IAO:0000225
name: obsolescence reason specification
def: "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." []
is_a: IAO:0000102 ! data about an ontology part
property_value: editor_note "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology." xsd:string
property_value: IAO:0000111 "obsolescence reason specification" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string
property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string

[Term]
id: IAO:0000409
name: denotator type
def: "A denotator type indicates how a term should be interpreted from an ontological perspective." []
is_a: IAO:0000102 ! data about an ontology part
property_value: IAO:0000111 "denotator type" xsd:string
property_value: IAO:0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities." xsd:string
property_value: IAO:0000117 "Alan Ruttenberg" xsd:string
property_value: IAO:0000119 "Barry Smith, Werner Ceusters" xsd:string

[Term]
id: IAO:0000577
name: centrally registered identifier symbol
def: "A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry." []
is_a: IAO:0000028 ! symbol
relationship: part_of IAO:0000578 ! centrally registered identifier
property_value: IAO:0000112 "The sentence \"The article has Pubmed ID 12345.\" contains a CRID that has two parts: one part is the CRID symbol, which is '12345'; the other part denotes the CRID registry, which is Pubmed." xsd:string
property_value: IAO:0000114 IAO:0000120
property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string
property_value: IAO:0000117 "PERSON: Bill Hogan" xsd:string
property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string
property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string
property_value: IAO:0000118 "CRID symbol" xsd:string
property_value: IAO:0000119 "Original proposal from Bjoern, discussions at IAO calls" xsd:string

[Term]
id: IAO:0000578
name: centrally registered identifier
def: "An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs." []
is_a: IAO:0020000 ! identifier
relationship: has_part IAO:0000577 ! centrally registered identifier symbol
property_value: editor_note "2014-05-05: In defining this term we take no position on what the CRID denotes. In particular do not assume it denotes a *record* in the CRID registry (since the registry might not have 'records')." xsd:string
property_value: editor_note "Alan, IAO call 20101124: potentially the CRID denotes the instance it was associated with during creation." xsd:string
property_value: editor_note "Note, IAO call 20101124: URIs are not always CRID, as not centrally registered. We acknowledge that CRID is a subset of a larger identifier class, but this subset fulfills our current needs. OBI PURLs are CRID as they are registered with OCLC. UPCs (Universal Product Codes from AC Nielsen)are not CRID as they are not centrally registered." xsd:string
property_value: IAO:0000112 "The sentence \"The article has Pubmed ID 12345.\" contains a CRID that has two parts: one part is the CRID symbol, which is '12345'; the other part denotes the CRID registry, which is Pubmed." xsd:string
property_value: IAO:0000114 IAO:0000120
property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string
property_value: IAO:0000117 "PERSON: Bill Hogan" xsd:string
property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string
property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string
property_value: IAO:0000118 "CRID" xsd:string
property_value: IAO:0000119 "Original proposal from Bjoern, discussions at IAO calls" xsd:string

[Term]
id: IAO:0000579
name: centrally registered identifier registry
def: "A code set of CRID records, each consisting of a CRID symbol and additional information which was recorded in the code set through an assigning a centrally registered identifier process." []
is_a: IAO:0020020 ! code set
property_value: IAO:0000112 "PubMed is a CRID registry. It has a code set of PubMed identifiers associated with journal articles. " xsd:string
property_value: IAO:0000114 IAO:0000120
property_value: IAO:0000117 "Justin Whorton" xsd:string
property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string
property_value: IAO:0000117 "PERSON: Bill Hogan" xsd:string
property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string
property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string
property_value: IAO:0000118 "CRID registry" xsd:string
property_value: IAO:0000119 "Original proposal from Bjoern, discussions at IAO calls" xsd:string
property_value: IAO:0000233 "https://github.com/information-artifact-ontology/IAO/issues/237" xsd:string

[Term]
id: IAO:0020000
name: identifier
def: "An information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity." []
comment: Sep 29, 2016: The current definition has been amended from the previous version: "A proper name is an information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity." to more accuratly reflect the necessary and sufficient condition on the class. (MB)
is_a: IAO:0000030 ! information content entity
intersection_of: IAO:0000030 ! information content entity
intersection_of: IAO:0000219 BFO:0000001 ! denotes entity
intersection_of: OBI:0000312 IAO:0020010 ! is_specified_output_of identifier creating process
relationship: IAO:0000219 BFO:0000001 ! denotes entity
relationship: OBI:0000312 IAO:0020010 ! is_specified_output_of identifier creating process
property_value: dc-creator "Mathias Brochhausen" xsd:string
property_value: IAO:0000111 "identifier" xsd:string
property_value: IAO:0000117 "Justin Whorton" xsd:string
property_value: IAO:0000117 "Mathias Brochhausen" xsd:string
property_value: IAO:0000118 "proper name" xsd:string
property_value: IAO:0000233 "https://github.com/information-artifact-ontology/IAO/issues/237" xsd:string

[Term]
id: IAO:0020010
name: identifier creating process
def: "A planned process that provides a reference to an individual entity shared by a group of subscribers to refer to that individual entity." []
is_a: OBI:0000011 ! planned process
intersection_of: OBI:0000011 ! planned process
intersection_of: OBI:0000299 IAO:0020000 ! has_specified_output identifier
relationship: OBI:0000299 IAO:0020000 ! has_specified_output identifier
property_value: dc-creator "Mathias Brochhausen" xsd:string
property_value: IAO:0000117 "Justin Whorton" xsd:string
property_value: IAO:0000117 "Mathias Brochhausen" xsd:string
property_value: IAO:0000118 "dubbing process" xsd:string
property_value: IAO:0000118 "naming" xsd:string
property_value: IAO:0000233 "https://github.com/information-artifact-ontology/IAO/issues/237" xsd:string

[Term]
id: IAO:0020020
name: code set
def: "An information content entity that is a collection of other information content entities that has been created to identify or annotate things in a specified domain, and where the intention of its creators is that the collection has a one-to-one correspondence with those things." []
comment: Code sets might include non-entities/things (e.g. missing thumbs).
comment: Does not imply absence vs. presence of any taxonomy.
comment: Does not imply that aggregated entities denote particulars, universals, or defined classes (a.k.a. attributive collections) or even that they denote only one of these three types of entities.
comment: Each aggregated entity is often (but not necessarily) associated with a text string—variously called a “description,” “name,” “title,” or “label”—that helps humans reach the target of denotation.\n\nWhen there is no such string, it is almost always because the entities take the form of human language words. For example, a “sex” or “gender” code set could contain “MALE” and “FEMALE,” or even “M” and “F” (by convention, we understand what these mean).
comment: For each given domain, there can potentially exist multiple code sets. The multiplicity of code sets is partially due to the different specific purposes of those code sets.
comment: For National Drug Codes (NDCs) and similar code sets, there doesn’t even have to be a single, fully-concretized copy somewhere (for example, for NDCs there is no centralized database or repository where they all live as one instance of concretization of code set). The code set can be “distributively” concretized. This seems like an unusual exception, but it also likely applies to Universal Product Codes (UPCs) and their follow on Global Trade Item Numbers (GTINs).
comment: Many code sets are created for a specific purpose in addition to merely identifying or annotating core ideas of a specified domain.
comment: The information content entities do not denote each other.
is_a: IAO:0000030 ! information content entity
relationship: has_part IAO:0020000 ! identifier
property_value: http://purl.org/dc/elements/1.1/contributor "Alan Ruttenberg" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor "Clint Dowland" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor "Matt Diller" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor "Sarah Bost" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor "William R. Hogan" xsd:string
property_value: IAO:0000117 "Alan Ruttenberg" xsd:string
property_value: IAO:0000117 "Justin Whorton" xsd:string
property_value: IAO:0000117 "Mathias Brochhausen" xsd:string
property_value: IAO:0000118 "code map" xsd:string
property_value: IAO:0000118 "code system" xsd:string
property_value: IAO:0000118 "codeset" xsd:string
property_value: IAO:0000118 "coding system" xsd:string
property_value: IAO:0000118 "controlled vocabulary" xsd:string
property_value: IAO:0000233 "https://github.com/information-artifact-ontology/IAO/issues/237" xsd:string

[Term]
id: NBO:0000001
name: body part movement
namespace: behavior_ontology
def: "A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC]" []
synonym: "stationary movement" EXACT []
is_a: NBO:0000338 ! kinesthetic behavior
property_value: http://purl.org/dc/elements/1.1/date "2011-04-14T01:03:39Z" xsd:string
created_by: George Gkoutos

[Term]
id: NBO:0000007
name: mouth movement
namespace: behavior_ontology
def: "The act of moving any of the tissues and hard structures surrounding the mouth other than teeth, jaws or filter structures [NBO:AC]" []
synonym: "mouth part movement" NARROW []
synonym: "other moved mouth parts" NARROW []
is_a: NBO:0000001 ! body part movement
property_value: http://purl.org/dc/elements/1.1/date "2011-04-14T01:03:39Z" xsd:string
created_by: George Gkoutos

[Term]
id: NBO:0000073
name: chewing
namespace: behavior_ontology
def: "The act of repeated grinding, tearing, and or crushing with teeth or jaws [NBO:SMAC]" []
synonym: "chew" EXACT []
synonym: "gnaw" EXACT []
synonym: "mastication" EXACT []
is_a: NBO:0000747 ! jaw movement
property_value: http://purl.org/dc/elements/1.1/date "2011-04-14T01:20:02Z" xsd:string
created_by: George Gkoutos

[Term]
id: NBO:0000313
name: behavior process
namespace: behavior_ontology
alt_id: NBO:0000000
def: "\"The action, reaction, or performance of an organism in response to external or internal stimuli.\" [GO:GO\\:0007610]" []
synonym: "behavior" EXACT []
synonym: "behaviour" EXACT []
xref: GO:0007610
is_a: GO:0007610 ! behavior
property_value: http://purl.org/dc/elements/1.1/date "2011-04-05T09:53:10Z" xsd:string
created_by: George Gkoutos

[Term]
id: NBO:0000338
name: kinesthetic behavior
namespace: behavior_ontology
def: "\"Movement behavior of the body or its parts.\"" []
is_a: NBO:0000313 ! behavior process
property_value: http://purl.org/dc/elements/1.1/date "2011-04-05T02:08:47Z" xsd:string
created_by: George Gkoutos

[Term]
id: NBO:0000747
name: jaw movement
namespace: behavior_ontology
is_a: NBO:0000007 ! mouth movement
property_value: http://purl.org/dc/elements/1.1/date "2012-03-17T09:51:17Z" xsd:string
created_by: gkoutos

[Term]
id: NBO:0001786
name: regulation of behavior
def: "\"Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.\" [GO:0050795]" []
xref: GO:0050795
is_a: NBO:0000313 ! behavior process
relationship: regulates NBO:0000313 ! behavior process
created_by: George Gkoutos

[Term]
id: NCBITaxon:1
name: root
namespace: ncbi_taxonomy
synonym: "all" RELATED synonym []
xref: GC_ID:1
xref: PMID:30365038
xref: PMID:32761142

[Term]
id: NCBITaxon:10066
name: Muridae
namespace: ncbi_taxonomy
xref: GC_ID:1
xref: PMID:15371245
is_a: NCBITaxon:337687 ! Muroidea
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:10088
name: Mus <genus>
namespace: ncbi_taxonomy
synonym: "mice" EXACT OMO:0003003 []
synonym: "mouse" EXACT OMO:0003003 []
synonym: "Mus" EXACT scientific_name []
xref: GC_ID:1
is_a: NCBITaxon:39107 ! Murinae
disjoint_from: NCBITaxon:10114 ! Rattus
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:10090
name: Mus musculus
namespace: ncbi_taxonomy
alt_id: NCBITaxon:85055
synonym: "house mouse" EXACT genbank_common_name []
synonym: "mouse" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:862507 ! Mus <subgenus>
property_value: has_rank NCBITaxon:species

[Term]
id: NCBITaxon:10114
name: Rattus
namespace: ncbi_taxonomy
synonym: "rat" EXACT OMO:0003003 []
synonym: "rats" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:39107 ! Murinae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:105389
name: Sedentaria
namespace: ncbi_taxonomy
synonym: "Palpata" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:6341 ! Polychaeta
property_value: has_rank NCBITaxon:subclass

[Term]
id: NCBITaxon:105391
name: Canalipalpata
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:105389 ! Sedentaria
property_value: has_rank NCBITaxon:infraclass

[Term]
id: NCBITaxon:110814
name: Xenoturbellida
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:1312402 ! Xenacoelomorpha
disjoint_from: NCBITaxon:147099 ! Acoelomorpha
property_value: has_rank NCBITaxon:subphylum

[Term]
id: NCBITaxon:110815
name: Xenoturbella
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:1547233 ! Xenoturbellidae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:117565
name: Myxini
namespace: ncbi_taxonomy
synonym: "Agnatha" RELATED in_part []
synonym: "fish" EXACT OMO:0003003 []
synonym: "fishes" EXACT OMO:0003003 []
synonym: "Hyperotreti" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:1476529 ! Cyclostomata
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:117570
name: Teleostomi
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:7776 ! Gnathostomata <vertebrates>
disjoint_from: NCBITaxon:7777 ! Chondrichthyes
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:117571
name: Euteleostomi
namespace: ncbi_taxonomy
alt_id: NCBITaxon:40673
synonym: "bony vertebrates" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:117570 ! Teleostomi
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:119089
name: Chromadorea
namespace: ncbi_taxonomy
alt_id: NCBITaxon:27837
synonym: "Adenophorea" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:6231 ! Nematoda
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:1206794
name: Ecdysozoa
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:33317 ! Protostomia
disjoint_from: NCBITaxon:2697495 ! Spiralia
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:1206795
name: Lophotrochozoa
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:2697495 ! Spiralia
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:123365
name: Neoteleostei
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:1489388 ! Euteleosteomorpha
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:123366
name: Eurypterygia
namespace: ncbi_taxonomy
synonym: "Eurypterygii" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:123365 ! Neoteleostei
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:123367
name: Ctenosquamata
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:123366 ! Eurypterygia
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:123368
name: Acanthomorphata
namespace: ncbi_taxonomy
synonym: "Acanthomorpha" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:123367 ! Ctenosquamata
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:123369
name: Euacanthomorphacea
namespace: ncbi_taxonomy
synonym: "Euacanthomorpha" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:123368 ! Acanthomorphata
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:124129
name: Acipenserinae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:7900 ! Acipenseridae
property_value: has_rank NCBITaxon:subfamily

[Term]
id: NCBITaxon:124130
name: Acipenserini
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:124129 ! Acipenserinae
property_value: has_rank NCBITaxon:tribe

[Term]
id: NCBITaxon:131209
name: Zygnemophyceae
namespace: ncbi_taxonomy
synonym: "Conjugatophyceae" RELATED synonym []
synonym: "Gamophyceae" RELATED synonym []
synonym: "Gamophyta" RELATED synonym []
synonym: "gamophytes" EXACT OMO:0003003 []
synonym: "Zygnematophyceae" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:131221 ! Streptophytina
disjoint_from: NCBITaxon:3193 ! Embryophyta
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:131221
name: Streptophytina
namespace: ncbi_taxonomy
synonym: "Charophyta/Embryophyta group" RELATED synonym []
synonym: "charophyte/embryophyte group" EXACT equivalent_name []
xref: GC_ID:1
is_a: NCBITaxon:35493 ! Streptophyta
property_value: has_rank NCBITaxon:subphylum

[Term]
id: NCBITaxon:1312402
name: Xenacoelomorpha
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:33213 ! Bilateria
disjoint_from: NCBITaxon:33317 ! Protostomia
disjoint_from: NCBITaxon:33511 ! Deuterostomia
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:131567
name: cellular organisms
namespace: ncbi_taxonomy
synonym: "biota" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:1 ! root

[Term]
id: NCBITaxon:1329799
name: Archelosauria
namespace: ncbi_taxonomy
synonym: "Archosauria-Testudines" RELATED synonym []
synonym: "Testudines + Archosauria group" RELATED synonym []
xref: GC_ID:1
xref: PMID:22839753
xref: PMID:25450099
is_a: NCBITaxon:32561 ! Sauria
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:1338369
name: Dipnotetrapodomorpha
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:8287 ! Sarcopterygii
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:142796
name: Eumycetozoa
namespace: ncbi_taxonomy
synonym: "Eumycetozoa Zopf, 1884" RELATED synonym []
synonym: "Mycetozoa" RELATED synonym []
synonym: "mycetozoans" RELATED synonym []
xref: GC_ID:1
xref: PMID:11062127
xref: PMID:9342353
is_a: NCBITaxon:2605435 ! Evosea
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:1437010
name: Boreoeutheria
namespace: ncbi_taxonomy
synonym: "Boreotheria" RELATED synonym []
xref: GC_ID:1
xref: PMID:11743200
xref: PMID:11791233
is_a: NCBITaxon:9347 ! Eutheria
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:1437180
name: Acrogymnospermae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:58024 ! Spermatophyta
disjoint_from: NCBITaxon:3398 ! Magnoliopsida
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:1445966
name: Gnetidae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:3372 ! Gnetopsida
property_value: has_rank NCBITaxon:subclass

[Term]
id: NCBITaxon:147099
name: Acoelomorpha
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:1312402 ! Xenacoelomorpha
property_value: has_rank NCBITaxon:subphylum

[Term]
id: NCBITaxon:147537
name: Saccharomycotina
namespace: ncbi_taxonomy
synonym: "true yeasts" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:716545 ! saccharomyceta
property_value: has_rank NCBITaxon:subphylum

[Term]
id: NCBITaxon:147554
name: Schizosaccharomycetes
namespace: ncbi_taxonomy
synonym: "Archiascomycota" RELATED in_part []
xref: GC_ID:1
is_a: NCBITaxon:451866 ! Taphrinomycotina
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:1476529
name: Cyclostomata
namespace: ncbi_taxonomy
synonym: "Agnatha" RELATED synonym []
synonym: "jawless vertebrates" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:7742 ! Vertebrata <vertebrates>
disjoint_from: NCBITaxon:7776 ! Gnathostomata <vertebrates>
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:1489341
name: Osteoglossocephalai
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:32443 ! Teleostei
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:1489388
name: Euteleosteomorpha
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:186625 ! Clupeocephala
disjoint_from: NCBITaxon:186634 ! Otomorpha
property_value: has_rank NCBITaxon:cohort

[Term]
id: NCBITaxon:1489872
name: Percomorphaceae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:123369 ! Euacanthomorphacea
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:1489922
name: Eupercaria
namespace: ncbi_taxonomy
synonym: "Percomorpharia" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:1489872 ! Percomorphaceae
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:1547233
name: Xenoturbellidae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:110814 ! Xenoturbellida
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:186622
name: Acipenseroidei
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:7899 ! Acipenseriformes
property_value: has_rank NCBITaxon:suborder

[Term]
id: NCBITaxon:186623
name: Actinopteri
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:7898 ! Actinopterygii
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:186625
name: Clupeocephala
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:1489341 ! Osteoglossocephalai

[Term]
id: NCBITaxon:186626
name: Otophysi
namespace: ncbi_taxonomy
synonym: "Otophysa" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:32519 ! Ostariophysi
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:186627
name: Cypriniphysae
namespace: ncbi_taxonomy
synonym: "Cypriniphysi" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:186626 ! Otophysi
property_value: has_rank NCBITaxon:superorder

[Term]
id: NCBITaxon:186634
name: Otomorpha
namespace: ncbi_taxonomy
synonym: "Ostarioclupeomorpha" RELATED synonym []
synonym: "Otocephala" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:186625 ! Clupeocephala
property_value: has_rank NCBITaxon:cohort

[Term]
id: NCBITaxon:1963758
name: Myomorpha
namespace: ncbi_taxonomy
synonym: "mice and others" EXACT genbank_common_name []
synonym: "Sciurognathi" RELATED in_part []
xref: GC_ID:1
is_a: NCBITaxon:9989 ! Rodentia
property_value: has_rank NCBITaxon:suborder

[Term]
id: NCBITaxon:197562
name: Pancrustacea
namespace: ncbi_taxonomy
xref: GC_ID:1
xref: PMID:10874751
xref: PMID:11557979
is_a: NCBITaxon:197563 ! Mandibulata
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:197563
name: Mandibulata
namespace: ncbi_taxonomy
synonym: "mandibulates" EXACT OMO:0003003 []
xref: GC_ID:1
xref: PMID:11557979
xref: PMID:9727836
is_a: NCBITaxon:6656 ! Arthropoda
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:2
name: Bacteria
namespace: ncbi_taxonomy
synonym: "bacteria" RELATED blast_name []
synonym: "eubacteria" EXACT genbank_common_name []
synonym: "Monera" RELATED in_part []
synonym: "Procaryotae" RELATED in_part []
synonym: "Prokaryota" RELATED in_part []
synonym: "Prokaryotae" RELATED in_part []
synonym: "prokaryote" RELATED in_part []
synonym: "prokaryotes" RELATED in_part []
xref: GC_ID:11
xref: PMID:10425795
xref: PMID:10425796
xref: PMID:10425797
xref: PMID:10490293
xref: PMID:10843050
xref: PMID:10939651
xref: PMID:10939673
xref: PMID:10939677
xref: PMID:11211268
xref: PMID:11321083
xref: PMID:11321113
xref: PMID:11411719
xref: PMID:11540071
xref: PMID:11542017
xref: PMID:11542087
xref: PMID:11760965
xref: PMID:12054223
xref: PMID:2112744
xref: PMID:270744
xref: PMID:32628106
xref: PMID:36748408
xref: PMID:7520741
xref: PMID:8123559
xref: PMID:8186100
xref: PMID:8590690
xref: PMID:9103655
xref: PMID:9336922
is_a: NCBITaxon:131567 ! cellular organisms
disjoint_from: NCBITaxon:2157 ! Archaea
disjoint_from: NCBITaxon:2759 ! Eukaryota
property_value: has_rank NCBITaxon:superkingdom

[Term]
id: NCBITaxon:2058185
name: Dictyosteliaceae
namespace: ncbi_taxonomy
xref: GC_ID:1
xref: PMID:29367151
is_a: NCBITaxon:2058949 ! Dictyosteliales
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:2058949
name: Dictyosteliales
namespace: ncbi_taxonomy
xref: GC_ID:1
xref: PMID:29367151
is_a: NCBITaxon:33083 ! Dictyostelia
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:207598
name: Homininae
namespace: ncbi_taxonomy
synonym: "Homo/Pan/Gorilla group" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:9604 ! Hominidae
property_value: has_rank NCBITaxon:subfamily

[Term]
id: NCBITaxon:2157
name: Archaea
namespace: ncbi_taxonomy
synonym: "archaea" RELATED blast_name []
synonym: "Archaebacteria" RELATED synonym []
synonym: "Mendosicutes" RELATED synonym []
synonym: "Metabacteria" RELATED synonym []
synonym: "Monera" RELATED in_part []
synonym: "Procaryotae" RELATED in_part []
synonym: "Prokaryota" RELATED in_part []
synonym: "Prokaryotae" RELATED in_part []
synonym: "prokaryote" RELATED in_part []
synonym: "prokaryotes" RELATED in_part []
xref: GC_ID:11
xref: PMID:10425795
xref: PMID:10425796
xref: PMID:10425797
xref: PMID:10490293
xref: PMID:10843050
xref: PMID:10939651
xref: PMID:10939673
xref: PMID:10939677
xref: PMID:11211268
xref: PMID:11321083
xref: PMID:11321113
xref: PMID:11411719
xref: PMID:11540071
xref: PMID:11541975
xref: PMID:11542064
xref: PMID:11542149
xref: PMID:11760965
xref: PMID:12054223
xref: PMID:2112744
xref: PMID:25527841
xref: PMID:270744
xref: PMID:32628106
xref: PMID:36748408
xref: PMID:8123559
xref: PMID:8590690
xref: PMID:9103655
xref: PMID:9336922
is_a: NCBITaxon:131567 ! cellular organisms
disjoint_from: NCBITaxon:2759 ! Eukaryota
property_value: has_rank NCBITaxon:superkingdom

[Term]
id: NCBITaxon:2301116
name: Rhabditina
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:6236 ! Rhabditida
property_value: has_rank NCBITaxon:suborder

[Term]
id: NCBITaxon:2301119
name: Rhabditomorpha
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:2301116 ! Rhabditina
property_value: has_rank NCBITaxon:infraorder

[Term]
id: NCBITaxon:2605435
name: Evosea
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:554915 ! Amoebozoa
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:2611352
name: Discoba
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:2759 ! Eukaryota
disjoint_from: NCBITaxon:2698737 ! Sar
disjoint_from: NCBITaxon:33090 ! Viridiplantae
disjoint_from: NCBITaxon:33154 ! Opisthokonta
disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae
disjoint_from: NCBITaxon:554915 ! Amoebozoa
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:262014
name: Xenopus <subgenus>
namespace: ncbi_taxonomy
synonym: "Xenopus" EXACT scientific_name []
xref: GC_ID:1
is_a: NCBITaxon:8353 ! Xenopus <genus>
property_value: has_rank NCBITaxon:subgenus

[Term]
id: NCBITaxon:2684882
name: Zygnematophycidae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:131209 ! Zygnemophyceae
property_value: has_rank NCBITaxon:subclass

[Term]
id: NCBITaxon:2697495
name: Spiralia
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:33317 ! Protostomia
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:2698737
name: Sar
namespace: ncbi_taxonomy
synonym: "SAR supergroup" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:2759 ! Eukaryota
disjoint_from: NCBITaxon:33090 ! Viridiplantae
disjoint_from: NCBITaxon:33154 ! Opisthokonta
disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae
disjoint_from: NCBITaxon:554915 ! Amoebozoa
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:2743709
name: Danionidae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:30727 ! Cyprinoidei
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:2743711
name: Danioninae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:2743709 ! Danionidae
property_value: has_rank NCBITaxon:subfamily

[Term]
id: NCBITaxon:2759
name: Eukaryota
namespace: ncbi_taxonomy
synonym: "Eucarya" RELATED synonym []
synonym: "Eucaryotae" RELATED synonym []
synonym: "eucaryotes" EXACT genbank_common_name []
synonym: "euk-" RELATED PRO-short-label [PRO:DAN]
synonym: "Eukarya" RELATED synonym []
synonym: "Eukaryotae" RELATED synonym []
synonym: "eukaryotes" EXACT OMO:0003003 []
synonym: "eukaryotes" RELATED blast_name []
xref: GC_ID:1
xref: PMID:23020233
xref: PMID:30257078
is_a: NCBITaxon:131567 ! cellular organisms
is_a: OBI:0100026 ! organism
property_value: has_rank NCBITaxon:superkingdom

[Term]
id: NCBITaxon:30319
name: Pipoidea
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:8342 ! Anura
property_value: has_rank NCBITaxon:superfamily

[Term]
id: NCBITaxon:30727
name: Cyprinoidei
namespace: ncbi_taxonomy
synonym: "Cyprinoidea" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:7952 ! Cypriniformes
property_value: has_rank NCBITaxon:suborder

[Term]
id: NCBITaxon:31022
name: Tetraodontiformes
namespace: ncbi_taxonomy
synonym: "pufferfishes and others" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:1489922 ! Eupercaria
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:31028
name: Tetraodontoidei
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:31022 ! Tetraodontiformes
property_value: has_rank NCBITaxon:suborder

[Term]
id: NCBITaxon:31031
name: Tetraodontidae
namespace: ncbi_taxonomy
synonym: "puffer fishes" EXACT OMO:0003003 []
synonym: "puffers" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:32517 ! Tetradontoidea
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:31032
name: Takifugu
namespace: ncbi_taxonomy
synonym: "Fugu" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:31031 ! Tetraodontidae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:31033
name: Takifugu rubripes
namespace: ncbi_taxonomy
synonym: "Fugu rubripes" RELATED synonym []
synonym: "Sphaeroides rubripes" RELATED synonym []
synonym: "Tetraodon rubripes" RELATED synonym []
synonym: "tiger puffer" EXACT OMO:0003003 []
synonym: "torafugu" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:31032 ! Takifugu
property_value: has_rank NCBITaxon:species

[Term]
id: NCBITaxon:314146
name: Euarchontoglires
namespace: ncbi_taxonomy
xref: GC_ID:1
xref: PMID:11214319
xref: PMID:12082125
xref: PMID:12878460
xref: PMID:15522813
is_a: NCBITaxon:1437010 ! Boreoeutheria
property_value: has_rank NCBITaxon:superorder

[Term]
id: NCBITaxon:314147
name: Glires
namespace: ncbi_taxonomy
synonym: "Rodents and rabbits" EXACT genbank_common_name []
xref: GC_ID:1
xref: PMID:11214319
xref: PMID:12082125
xref: PMID:15522813
is_a: NCBITaxon:314146 ! Euarchontoglires
disjoint_from: NCBITaxon:9443 ! Primates
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:314293
name: Simiiformes
namespace: ncbi_taxonomy
synonym: "Anthropoidea" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:376913 ! Haplorrhini
property_value: has_rank NCBITaxon:infraorder

[Term]
id: NCBITaxon:314295
name: Hominoidea
namespace: ncbi_taxonomy
synonym: "ape" EXACT OMO:0003003 []
synonym: "apes" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:9526 ! Catarrhini
property_value: has_rank NCBITaxon:superfamily

[Term]
id: NCBITaxon:3176
name: Zygnematales
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:2684882 ! Zygnematophycidae
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:3193
name: Embryophyta
namespace: ncbi_taxonomy
synonym: "higher plants" EXACT OMO:0003003 []
synonym: "land plants" EXACT OMO:0003003 []
synonym: "land plants" RELATED blast_name []
synonym: "plants" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:131221 ! Streptophytina
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:32341
name: Sophophora
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:7215 ! Drosophila <flies,genus>
property_value: has_rank NCBITaxon:subgenus

[Term]
id: NCBITaxon:32346
name: melanogaster group
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:32341 ! Sophophora
property_value: has_rank NCBITaxon:species_group

[Term]
id: NCBITaxon:32351
name: melanogaster subgroup
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:32346 ! melanogaster group
property_value: has_rank NCBITaxon:species_subgroup

[Term]
id: NCBITaxon:32440
name: Chondrostei
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:186623 ! Actinopteri
disjoint_from: NCBITaxon:41665 ! Neopterygii
property_value: has_rank NCBITaxon:subclass

[Term]
id: NCBITaxon:32443
name: Teleostei
namespace: ncbi_taxonomy
synonym: "teleost fishes" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:41665 ! Neopterygii
property_value: has_rank NCBITaxon:infraclass

[Term]
id: NCBITaxon:32517
name: Tetradontoidea
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:31028 ! Tetraodontoidei
property_value: has_rank NCBITaxon:superfamily

[Term]
id: NCBITaxon:32519
name: Ostariophysi
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:186634 ! Otomorpha
property_value: has_rank NCBITaxon:subcohort

[Term]
id: NCBITaxon:32523
name: Tetrapoda
namespace: ncbi_taxonomy
synonym: "tetrapods" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:1338369 ! Dipnotetrapodomorpha
disjoint_from: NCBITaxon:7878 ! Dipnomorpha
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:32524
name: Amniota
namespace: ncbi_taxonomy
synonym: "amniotes" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:32523 ! Tetrapoda
disjoint_from: NCBITaxon:8292 ! Amphibia
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:32525
name: Theria <mammals>
namespace: ncbi_taxonomy
synonym: "Theria" EXACT scientific_name []
xref: GC_ID:1
is_a: NCBITaxon:40674 ! Mammalia
disjoint_from: NCBITaxon:9254 ! Prototheria
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:32561
name: Sauria
namespace: ncbi_taxonomy
synonym: "Diapsida" RELATED synonym []
synonym: "diapsids" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:8457 ! Sauropsida
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:33083
name: Dictyostelia
namespace: ncbi_taxonomy
synonym: "cellular slime molds" RELATED blast_name []
synonym: "dictyostelid cellular slime molds" EXACT genbank_common_name []
synonym: "Dictyostelida" RELATED synonym []
synonym: "Dictyostelids" RELATED synonym []
synonym: "Dictyosteliida" RELATED synonym []
xref: GC_ID:1
xref: PMID:11062127
xref: PMID:29367151
xref: PMID:9342353
is_a: NCBITaxon:142796 ! Eumycetozoa
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:33090
name: Viridiplantae
namespace: ncbi_taxonomy
synonym: "Chlorobionta" RELATED synonym []
synonym: "Chlorophyta/Embryophyta group" EXACT equivalent_name []
synonym: "chlorophyte/embryophyte group" EXACT equivalent_name []
synonym: "Chloroplastida" RELATED synonym []
synonym: "green plants" EXACT OMO:0003003 []
synonym: "green plants" RELATED blast_name []
xref: GC_ID:1
xref: PMID:16248873
xref: PMID:30257078
is_a: NCBITaxon:2759 ! Eukaryota
disjoint_from: NCBITaxon:33154 ! Opisthokonta
disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae
disjoint_from: NCBITaxon:554915 ! Amoebozoa
property_value: has_rank NCBITaxon:kingdom

[Term]
id: NCBITaxon:3312
name: Coniferophyta
namespace: ncbi_taxonomy
synonym: "conifers" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:1437180 ! Acrogymnospermae
disjoint_from: NCBITaxon:3372 ! Gnetopsida
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:33154
name: Opisthokonta
namespace: ncbi_taxonomy
synonym: "Fungi/Metazoa group" RELATED synonym []
synonym: "opisthokonts" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:2759 ! Eukaryota
disjoint_from: NCBITaxon:38254 ! Glaucocystophyceae
disjoint_from: NCBITaxon:554915 ! Amoebozoa
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:33208
name: Metazoa
namespace: ncbi_taxonomy
synonym: "Animalia" RELATED synonym []
synonym: "animals" RELATED blast_name []
synonym: "metazoans" EXACT genbank_common_name []
synonym: "multicellular animals" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:33154 ! Opisthokonta
disjoint_from: NCBITaxon:4751 ! Fungi
property_value: has_rank NCBITaxon:kingdom

[Term]
id: NCBITaxon:33213
name: Bilateria
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:6072 ! Eumetazoa
disjoint_from: NCBITaxon:6073 ! Cnidaria
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:33317
name: Protostomia
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:33213 ! Bilateria
disjoint_from: NCBITaxon:33511 ! Deuterostomia
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:33340
name: Neoptera
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:7496 ! Pterygota <insects>
property_value: has_rank NCBITaxon:infraclass

[Term]
id: NCBITaxon:33392
name: Endopterygota
namespace: ncbi_taxonomy
synonym: "Holometabola" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:33340 ! Neoptera
property_value: has_rank NCBITaxon:cohort

[Term]
id: NCBITaxon:33511
name: Deuterostomia
namespace: ncbi_taxonomy
synonym: "deuterostomes" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:33213 ! Bilateria
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:33630
name: Alveolata
namespace: ncbi_taxonomy
synonym: "alveolates" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:2698737 ! Sar
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:33682
name: Euglenozoa
namespace: ncbi_taxonomy
synonym: "Euglenozoans" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:2611352 ! Discoba
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:3372
name: Gnetopsida
namespace: ncbi_taxonomy
synonym: "Chlamydospermopsida" RELATED synonym []
synonym: "Gneticae" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:1437180 ! Acrogymnospermae
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:337687
name: Muroidea
namespace: ncbi_taxonomy
xref: GC_ID:1
xref: PMID:15019624
xref: PMID:15371245
is_a: NCBITaxon:1963758 ! Myomorpha
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:3378
name: Gnetales
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:1445966 ! Gnetidae
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:3398
name: Magnoliopsida
namespace: ncbi_taxonomy
synonym: "Angiospermae" RELATED synonym []
synonym: "angiosperms" EXACT OMO:0003003 []
synonym: "flowering plants" EXACT genbank_common_name []
synonym: "flowering plants" RELATED blast_name []
synonym: "Magnoliophyta" RELATED synonym []
xref: GC_ID:1
xref: PMID:25249442
is_a: NCBITaxon:58024 ! Spermatophyta
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:34346
name: Schizosaccharomycetales
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:147554 ! Schizosaccharomycetes
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:35493
name: Streptophyta
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:33090 ! Viridiplantae
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:376913
name: Haplorrhini
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:9443 ! Primates
property_value: has_rank NCBITaxon:suborder

[Term]
id: NCBITaxon:38254
name: Glaucocystophyceae
namespace: ncbi_taxonomy
synonym: "algae" RELATED in_part []
synonym: "glaucocystophytes" EXACT OMO:0003003 []
synonym: "Glaucophyceae" RELATED synonym []
synonym: "Glaucophyta" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:2759 ! Eukaryota
disjoint_from: NCBITaxon:554915 ! Amoebozoa
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:39107
name: Murinae
namespace: ncbi_taxonomy
alt_id: NCBITaxon:109679
xref: GC_ID:1
is_a: NCBITaxon:10066 ! Muridae
property_value: has_rank NCBITaxon:subfamily

[Term]
id: NCBITaxon:40674
name: Mammalia
namespace: ncbi_taxonomy
synonym: "mammals" EXACT genbank_common_name []
synonym: "mammals" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:32524 ! Amniota
disjoint_from: NCBITaxon:8457 ! Sauropsida
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:41324
name: Siboglinidae
namespace: ncbi_taxonomy
alt_id: NCBITaxon:167797
alt_id: NCBITaxon:27906
alt_id: NCBITaxon:29174
alt_id: NCBITaxon:41329
alt_id: NCBITaxon:54122
alt_id: NCBITaxon:55674
alt_id: NCBITaxon:55678
alt_id: NCBITaxon:6422
synonym: "Frenulata" RELATED synonym []
synonym: "Lamellibrachiidae" RELATED synonym []
synonym: "Obturata" RELATED synonym []
synonym: "Oligobrachiidae" RELATED synonym []
synonym: "Perviata" RELATED synonym []
synonym: "Pogonophora" RELATED synonym []
synonym: "pogonophores" EXACT OMO:0003003 []
synonym: "Polybrachiidae" RELATED synonym []
synonym: "Sclerolinidae" RELATED synonym []
synonym: "tube worms" RELATED blast_name []
synonym: "Vestimentifera" RELATED synonym []
synonym: "vestimentiferans" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:6362 ! Sabellida
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:41665
name: Neopterygii
namespace: ncbi_taxonomy
synonym: "Neopterygi" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:186623 ! Actinopteri
property_value: has_rank NCBITaxon:subclass

[Term]
id: NCBITaxon:41666
name: Batrachia
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:8292 ! Amphibia
property_value: has_rank NCBITaxon:superorder

[Term]
id: NCBITaxon:436486
name: Dinosauria
namespace: ncbi_taxonomy
synonym: "dinosaur" EXACT OMO:0003003 []
synonym: "dinosaurs" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:8492 ! Archosauria
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:436489
name: Saurischia
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:436486 ! Dinosauria
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:436491
name: Theropoda
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:436489 ! Saurischia
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:436492
name: Coelurosauria
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:436491 ! Theropoda
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:43733
name: Muscomorpha
namespace: ncbi_taxonomy
alt_id: NCBITaxon:43732
synonym: "Asilomorpha" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:7203 ! Brachycera
property_value: has_rank NCBITaxon:infraorder

[Term]
id: NCBITaxon:43738
name: Schizophora
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:480117 ! Cyclorrhapha

[Term]
id: NCBITaxon:43741
name: Acalyptratae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:43738 ! Schizophora

[Term]
id: NCBITaxon:43746
name: Ephydroidea
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:43741 ! Acalyptratae
property_value: has_rank NCBITaxon:superfamily

[Term]
id: NCBITaxon:43845
name: Drosophilinae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:7214 ! Drosophilidae
property_value: has_rank NCBITaxon:subfamily

[Term]
id: NCBITaxon:451864
name: Dikarya
namespace: ncbi_taxonomy
xref: GC_ID:1
xref: PMID:15689432
xref: PMID:16151185
xref: PMID:17010206
xref: PMID:17051209
xref: PMID:17572334
is_a: NCBITaxon:4751 ! Fungi
property_value: has_rank NCBITaxon:subkingdom

[Term]
id: NCBITaxon:451866
name: Taphrinomycotina
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:4890 ! Ascomycota
disjoint_from: NCBITaxon:716545 ! saccharomyceta
property_value: has_rank NCBITaxon:subphylum

[Term]
id: NCBITaxon:46877
name: Drosophilini
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:43845 ! Drosophilinae
property_value: has_rank NCBITaxon:tribe

[Term]
id: NCBITaxon:4751
name: Fungi
namespace: ncbi_taxonomy
synonym: "fungi" RELATED blast_name []
synonym: "Mycota" RELATED synonym []
xref: GC_ID:1
xref: PMID:11062127
xref: PMID:12684019
is_a: NCBITaxon:33154 ! Opisthokonta
property_value: has_rank NCBITaxon:kingdom

[Term]
id: NCBITaxon:480117
name: Cyclorrhapha
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:480118 ! Eremoneura
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:480118
name: Eremoneura
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:43733 ! Muscomorpha
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:4890
name: Ascomycota
namespace: ncbi_taxonomy
synonym: "ascomycete fungi" RELATED blast_name []
synonym: "ascomycetes" EXACT genbank_common_name []
synonym: "sac fungi" EXACT OMO:0003003 []
xref: GC_ID:1
xref: PMID:17572334
is_a: NCBITaxon:451864 ! Dikarya
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:4891
name: Saccharomycetes
namespace: ncbi_taxonomy
synonym: "Hemiascomycetes" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:147537 ! Saccharomycotina
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:4892
name: Saccharomycetales
namespace: ncbi_taxonomy
synonym: "budding yeasts" RELATED blast_name []
synonym: "Endomycetales" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:4891 ! Saccharomycetes
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:4893
name: Saccharomycetaceae
namespace: ncbi_taxonomy
alt_id: NCBITaxon:221665
alt_id: NCBITaxon:44280
xref: GC_ID:1
is_a: NCBITaxon:4892 ! Saccharomycetales
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:4894
name: Schizosaccharomycetaceae
namespace: ncbi_taxonomy
synonym: "fission yeasts" EXACT genbank_common_name []
synonym: "Schizosaccharomycetoideae" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:34346 ! Schizosaccharomycetales
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:4895
name: Schizosaccharomyces
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:4894 ! Schizosaccharomycetaceae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:4896
name: Schizosaccharomyces pombe
namespace: ncbi_taxonomy
alt_id: NCBITaxon:45042
synonym: "fission yeast" EXACT genbank_common_name []
synonym: "Schizosaccharomyces malidevorans" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:4895 ! Schizosaccharomyces
property_value: has_rank NCBITaxon:species

[Term]
id: NCBITaxon:4930
name: Saccharomyces
namespace: ncbi_taxonomy
alt_id: NCBITaxon:36915
synonym: "Pachytichospora" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:4893 ! Saccharomycetaceae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:4932
name: Saccharomyces cerevisiae
namespace: ncbi_taxonomy
alt_id: NCBITaxon:41870
synonym: "baker's yeast" EXACT OMO:0003003 []
synonym: "brewer's yeast" EXACT genbank_common_name []
synonym: "Candida robusta" RELATED synonym []
synonym: "Mycoderma cerevisiae" RELATED synonym []
synonym: "Saccharomyces capensis" RELATED synonym []
synonym: "Saccharomyces cerevisiae 'var. diastaticus'" EXACT equivalent_name []
synonym: "Saccharomyces diastaticus" RELATED synonym []
synonym: "Saccharomyces italicus" RELATED synonym []
synonym: "Saccharomyces oviformis" RELATED synonym []
synonym: "Saccharomyces uvarum var. melibiosus" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:4930 ! Saccharomyces
property_value: has_rank NCBITaxon:species

[Term]
id: NCBITaxon:50557
name: Insecta
namespace: ncbi_taxonomy
synonym: "insects" RELATED blast_name []
synonym: "true insects" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:6960 ! Hexapoda
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:554915
name: Amoebozoa
namespace: ncbi_taxonomy
xref: GC_ID:1
xref: PMID:23020233
xref: PMID:30257078
is_a: NCBITaxon:2759 ! Eukaryota
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:55879
name: Rhabditoidea
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:2301119 ! Rhabditomorpha
property_value: has_rank NCBITaxon:superfamily

[Term]
id: NCBITaxon:55885
name: Peloderinae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:6243 ! Rhabditidae
property_value: has_rank NCBITaxon:subfamily

[Term]
id: NCBITaxon:5782
name: Dictyostelium
namespace: ncbi_taxonomy
synonym: "Hyalostilbum" RELATED synonym []
xref: GC_ID:1
xref: PMID:29367151
is_a: NCBITaxon:2058185 ! Dictyosteliaceae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:58023
name: Tracheophyta
namespace: ncbi_taxonomy
synonym: "vascular plants" EXACT OMO:0003003 []
synonym: "vascular plants" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:3193 ! Embryophyta
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:58024
name: Spermatophyta
namespace: ncbi_taxonomy
synonym: "seed plants" EXACT OMO:0003003 []
synonym: "seed plants" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:78536 ! Euphyllophyta
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:6040
name: Porifera
namespace: ncbi_taxonomy
synonym: "Parazoa" RELATED synonym []
synonym: "sponges" EXACT genbank_common_name []
synonym: "sponges" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:33208 ! Metazoa
disjoint_from: NCBITaxon:6072 ! Eumetazoa
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:6072
name: Eumetazoa
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:33208 ! Metazoa
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:6073
name: Cnidaria
namespace: ncbi_taxonomy
synonym: "cnidarians" EXACT genbank_common_name []
synonym: "cnidarians" RELATED blast_name []
synonym: "Coelenterata" RELATED in_part []
synonym: "coelenterates" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:6072 ! Eumetazoa
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:6157
name: Platyhelminthes
namespace: ncbi_taxonomy
synonym: "flatworm" EXACT OMO:0003003 []
synonym: "flatworms" EXACT genbank_common_name []
synonym: "flatworms" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:1206795 ! Lophotrochozoa
disjoint_from: NCBITaxon:6340 ! Annelida
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:6231
name: Nematoda
namespace: ncbi_taxonomy
synonym: "Nemata" RELATED synonym []
synonym: "nematode" EXACT OMO:0003003 []
synonym: "nematodes" EXACT OMO:0003003 []
synonym: "nematodes" RELATED blast_name []
synonym: "roundworm" EXACT OMO:0003003 []
synonym: "roundworms" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:1206794 ! Ecdysozoa
disjoint_from: NCBITaxon:88770 ! Panarthropoda
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:6236
name: Rhabditida
namespace: ncbi_taxonomy
alt_id: NCBITaxon:33251
alt_id: NCBITaxon:6308
synonym: "Strongylida" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:119089 ! Chromadorea
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:6237
name: Caenorhabditis
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:55885 ! Peloderinae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:6239
name: Caenorhabditis elegans
namespace: ncbi_taxonomy
synonym: "Rhabditis elegans" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:6237 ! Caenorhabditis
property_value: has_rank NCBITaxon:species

[Term]
id: NCBITaxon:6243
name: Rhabditidae
namespace: ncbi_taxonomy
alt_id: NCBITaxon:54603
xref: GC_ID:1
is_a: NCBITaxon:55879 ! Rhabditoidea
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:6340
name: Annelida
namespace: ncbi_taxonomy
synonym: "annelid worms" EXACT genbank_common_name []
synonym: "segmented worms" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:1206795 ! Lophotrochozoa
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:6341
name: Polychaeta
namespace: ncbi_taxonomy
synonym: "polychaetes" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:6340 ! Annelida
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:6362
name: Sabellida
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:105391 ! Canalipalpata
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:6656
name: Arthropoda
namespace: ncbi_taxonomy
synonym: "arthropods" EXACT genbank_common_name []
synonym: "arthropods" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:88770 ! Panarthropoda
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:6960
name: Hexapoda
namespace: ncbi_taxonomy
synonym: "Atelocerata" RELATED in_part []
synonym: "hexapods" RELATED blast_name []
synonym: "insects" EXACT genbank_common_name []
synonym: "Tracheata" RELATED in_part []
synonym: "Uniramia" RELATED in_part []
xref: GC_ID:1
is_a: NCBITaxon:197562 ! Pancrustacea
property_value: has_rank NCBITaxon:subphylum

[Term]
id: NCBITaxon:7147
name: Diptera
namespace: ncbi_taxonomy
synonym: "flies" EXACT genbank_common_name []
synonym: "flies" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:33392 ! Endopterygota
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:716545
name: saccharomyceta
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:4890 ! Ascomycota
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:7203
name: Brachycera
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:7147 ! Diptera
property_value: has_rank NCBITaxon:suborder

[Term]
id: NCBITaxon:7214
name: Drosophilidae
namespace: ncbi_taxonomy
synonym: "pomace flies" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:43746 ! Ephydroidea
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:7215
name: Drosophila <flies,genus>
namespace: ncbi_taxonomy
alt_id: NCBITaxon:7326
synonym: "Drosophila" EXACT scientific_name []
synonym: "fruit flies" EXACT genbank_common_name []
synonym: "fruit fly" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:46877 ! Drosophilini
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:7227
name: Drosophila melanogaster
namespace: ncbi_taxonomy
alt_id: NCBITaxon:2267365
synonym: "fruit fly" EXACT genbank_common_name []
synonym: "Sophophora melanogaster" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:32351 ! melanogaster subgroup
property_value: has_rank NCBITaxon:species

[Term]
id: NCBITaxon:7496
name: Pterygota <insects>
namespace: ncbi_taxonomy
synonym: "Pterygota" EXACT scientific_name []
synonym: "winged insects" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:85512 ! Dicondylia
property_value: has_rank NCBITaxon:subclass

[Term]
id: NCBITaxon:7711
name: Chordata
namespace: ncbi_taxonomy
synonym: "chordates" EXACT genbank_common_name []
synonym: "chordates" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:33511 ! Deuterostomia
property_value: has_rank NCBITaxon:phylum

[Term]
id: NCBITaxon:7712
name: Tunicata
namespace: ncbi_taxonomy
synonym: "tunicates" EXACT genbank_common_name []
synonym: "tunicates" RELATED blast_name []
synonym: "Urochordata" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:7711 ! Chordata
disjoint_from: NCBITaxon:89593 ! Craniata <chordates>
property_value: has_rank NCBITaxon:subphylum

[Term]
id: NCBITaxon:7742
name: Vertebrata <vertebrates>
namespace: ncbi_taxonomy
synonym: "Vertebrata" EXACT scientific_name []
synonym: "vertebrates" EXACT genbank_common_name []
synonym: "vertebrates" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:89593 ! Craniata <chordates>
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:7761
name: Myxiniformes
namespace: ncbi_taxonomy
synonym: "hagfishes" RELATED blast_name []
synonym: "Myxinoidea" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:117565 ! Myxini
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:7762
name: Myxinidae
namespace: ncbi_taxonomy
synonym: "hagfishes" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:7761 ! Myxiniformes
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:7776
name: Gnathostomata <vertebrates>
namespace: ncbi_taxonomy
synonym: "Gnathostomata" EXACT scientific_name []
synonym: "jawed vertebrates" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:7742 ! Vertebrata <vertebrates>
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:7777
name: Chondrichthyes
namespace: ncbi_taxonomy
synonym: "cartilaginous fishes" EXACT genbank_common_name []
synonym: "cartilaginous fishes" RELATED blast_name []
synonym: "fish" EXACT OMO:0003003 []
synonym: "fishes" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:7776 ! Gnathostomata <vertebrates>
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:78536
name: Euphyllophyta
namespace: ncbi_taxonomy
synonym: "euphyllophytes" EXACT equivalent_name []
xref: GC_ID:1
is_a: NCBITaxon:58023 ! Tracheophyta
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:7863
name: Holocephali
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:7777 ! Chondrichthyes
property_value: has_rank NCBITaxon:subclass

[Term]
id: NCBITaxon:7864
name: Chimaeriformes
namespace: ncbi_taxonomy
synonym: "chimaeras" EXACT genbank_common_name []
synonym: "chimaeras" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:7863 ! Holocephali
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:7878
name: Dipnomorpha
namespace: ncbi_taxonomy
synonym: "Choanichthyes" RELATED in_part []
synonym: "Dipneusti" RELATED synonym []
synonym: "dipnoans" EXACT OMO:0003003 []
synonym: "Dipnoi" RELATED synonym []
synonym: "fish" EXACT OMO:0003003 []
synonym: "fishes" EXACT OMO:0003003 []
synonym: "lungfishes" EXACT genbank_common_name []
synonym: "lungfishes" RELATED blast_name []
synonym: "Osteichthyes" RELATED in_part []
xref: GC_ID:1
is_a: NCBITaxon:1338369 ! Dipnotetrapodomorpha
property_value: has_rank NCBITaxon:subclass

[Term]
id: NCBITaxon:7898
name: Actinopterygii
namespace: ncbi_taxonomy
synonym: "Actinopterygi" RELATED synonym []
synonym: "bony fishes" RELATED blast_name []
synonym: "fish" EXACT OMO:0003003 []
synonym: "fishes" EXACT OMO:0003003 []
synonym: "Osteichthyes" RELATED in_part []
synonym: "ray-finned fishes" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:117571 ! Euteleostomi
disjoint_from: NCBITaxon:8287 ! Sarcopterygii
property_value: has_rank NCBITaxon:superclass

[Term]
id: NCBITaxon:7899
name: Acipenseriformes
namespace: ncbi_taxonomy
synonym: "sturgeons and paddlefish" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:32440 ! Chondrostei
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:7900
name: Acipenseridae
namespace: ncbi_taxonomy
synonym: "sturgeons" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:186622 ! Acipenseroidei
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:7901
name: Acipenser
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:124130 ! Acipenserini
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:7952
name: Cypriniformes
namespace: ncbi_taxonomy
synonym: "carps and others" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:186627 ! Cypriniphysae
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:7954
name: Danio
namespace: ncbi_taxonomy
alt_id: NCBITaxon:46777
alt_id: NCBITaxon:487617
synonym: "Brachydanio" RELATED synonym []
synonym: "Celestichthys" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:2743711 ! Danioninae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:7955
name: Danio rerio
namespace: ncbi_taxonomy
alt_id: NCBITaxon:27702
alt_id: NCBITaxon:37966
synonym: "Brachydanio rerio" RELATED synonym []
synonym: "Brachydanio rerio frankei" RELATED synonym []
synonym: "Cyprinus rerio" RELATED synonym []
synonym: "Danio frankei" RELATED synonym []
synonym: "Danio rerio frankei" RELATED synonym []
synonym: "leopard danio" EXACT OMO:0003003 []
synonym: "zebra danio" EXACT OMO:0003003 []
synonym: "zebra fish" EXACT OMO:0003003 []
synonym: "zebrafish" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:7954 ! Danio
property_value: has_rank NCBITaxon:species

[Term]
id: NCBITaxon:8287
name: Sarcopterygii
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:117571 ! Euteleostomi
property_value: has_rank NCBITaxon:superclass

[Term]
id: NCBITaxon:8292
name: Amphibia
namespace: ncbi_taxonomy
synonym: "amphibians" EXACT genbank_common_name []
synonym: "amphibians" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:32523 ! Tetrapoda
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:8342
name: Anura
namespace: ncbi_taxonomy
synonym: "anurans" EXACT OMO:0003003 []
synonym: "frogs" EXACT OMO:0003003 []
synonym: "frogs & toads" RELATED blast_name []
synonym: "frogs and toads" EXACT genbank_common_name []
synonym: "Salientia" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:41666 ! Batrachia
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:8352
name: Pipidae
namespace: ncbi_taxonomy
synonym: "pipid frogs" EXACT OMO:0003003 []
synonym: "tongueless frogs" EXACT genbank_common_name []
xref: GC_ID:1
xref: PMID:2385174
is_a: NCBITaxon:30319 ! Pipoidea
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:8353
name: Xenopus <genus>
namespace: ncbi_taxonomy
synonym: "Xenopus" EXACT scientific_name []
xref: GC_ID:1
xref: PMID:2385174
is_a: NCBITaxon:8360 ! Xenopodinae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:8355
name: Xenopus laevis
namespace: ncbi_taxonomy
synonym: "African clawed frog" EXACT genbank_common_name []
synonym: "Bufo laevis" RELATED synonym []
synonym: "clawed frog" EXACT OMO:0003003 []
synonym: "common platanna" EXACT OMO:0003003 []
synonym: "platanna" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:262014 ! Xenopus <subgenus>
property_value: has_rank NCBITaxon:species

[Term]
id: NCBITaxon:8360
name: Xenopodinae
namespace: ncbi_taxonomy
synonym: "Siluraninae" RELATED synonym []
xref: GC_ID:1
xref: PMID:2385174
is_a: NCBITaxon:8352 ! Pipidae
property_value: has_rank NCBITaxon:subfamily

[Term]
id: NCBITaxon:8457
name: Sauropsida
namespace: ncbi_taxonomy
synonym: "sauropsids" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:32524 ! Amniota
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:8492
name: Archosauria
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:1329799 ! Archelosauria
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:85512
name: Dicondylia
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:50557 ! Insecta
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:862507
name: Mus <subgenus>
namespace: ncbi_taxonomy
synonym: "Mus" EXACT scientific_name []
xref: GC_ID:1
is_a: NCBITaxon:10088 ! Mus <genus>
property_value: has_rank NCBITaxon:subgenus

[Term]
id: NCBITaxon:8782
name: Aves
namespace: ncbi_taxonomy
synonym: "avian" RELATED synonym []
synonym: "birds" EXACT genbank_common_name []
synonym: "birds" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:436492 ! Coelurosauria
property_value: has_rank NCBITaxon:class

[Term]
id: NCBITaxon:8783
name: Palaeognathae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:8782 ! Aves
disjoint_from: NCBITaxon:8825 ! Neognathae
property_value: has_rank NCBITaxon:superorder

[Term]
id: NCBITaxon:8798
name: Struthioniformes
namespace: ncbi_taxonomy
synonym: "ostriches" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:8783 ! Palaeognathae
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:8799
name: Struthionidae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:8798 ! Struthioniformes
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:8800
name: Struthio
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:8799 ! Struthionidae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:8801
name: Struthio camelus
namespace: ncbi_taxonomy
synonym: "African ostrich" EXACT genbank_common_name []
synonym: "ostrich" EXACT OMO:0003003 []
synonym: "Struthio camelus domesticus" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:8800 ! Struthio
property_value: has_rank NCBITaxon:species

[Term]
id: NCBITaxon:8825
name: Neognathae
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:8782 ! Aves
property_value: has_rank NCBITaxon:infraclass

[Term]
id: NCBITaxon:88770
name: Panarthropoda
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:1206794 ! Ecdysozoa
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:8929
name: Columbiformes
namespace: ncbi_taxonomy
synonym: "pigeons and others" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:8825 ! Neognathae
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:8930
name: Columbidae
namespace: ncbi_taxonomy
synonym: "pigeons" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:8929 ! Columbiformes
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:89593
name: Craniata <chordates>
namespace: ncbi_taxonomy
synonym: "Craniata" EXACT scientific_name []
xref: GC_ID:1
is_a: NCBITaxon:7711 ! Chordata
property_value: has_rank NCBITaxon:subphylum

[Term]
id: NCBITaxon:9254
name: Prototheria
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:40674 ! Mammalia
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:9255
name: Monotremata
namespace: ncbi_taxonomy
synonym: "egg-laying mammals" EXACT genbank_common_name []
synonym: "monotremes" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:9254 ! Prototheria
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:9259
name: Tachyglossidae
namespace: ncbi_taxonomy
synonym: "echidnas" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:9255 ! Monotremata
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:9347
name: Eutheria
namespace: ncbi_taxonomy
synonym: "eutherian mammals" EXACT OMO:0003003 []
synonym: "placental mammals" EXACT OMO:0003003 []
synonym: "Placentalia" RELATED synonym []
synonym: "placentals" EXACT genbank_common_name []
synonym: "placentals" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:32525 ! Theria <mammals>
property_value: has_rank NCBITaxon:clade

[Term]
id: NCBITaxon:9443
name: Primates
namespace: ncbi_taxonomy
synonym: "Primata" RELATED synonym []
synonym: "primate" EXACT equivalent_name []
synonym: "primates" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:314146 ! Euarchontoglires
property_value: has_rank NCBITaxon:order

[Term]
id: NCBITaxon:9526
name: Catarrhini
namespace: ncbi_taxonomy
xref: GC_ID:1
is_a: NCBITaxon:314293 ! Simiiformes
property_value: has_rank NCBITaxon:parvorder

[Term]
id: NCBITaxon:9604
name: Hominidae
namespace: ncbi_taxonomy
synonym: "great apes" EXACT genbank_common_name []
synonym: "Pongidae" RELATED synonym []
xref: GC_ID:1
is_a: NCBITaxon:314295 ! Hominoidea
property_value: has_rank NCBITaxon:family

[Term]
id: NCBITaxon:9605
name: Homo
namespace: ncbi_taxonomy
synonym: "humans" EXACT OMO:0003003 []
xref: GC_ID:1
is_a: NCBITaxon:207598 ! Homininae
property_value: has_rank NCBITaxon:genus

[Term]
id: NCBITaxon:9606
name: Homo sapiens
namespace: ncbi_taxonomy
synonym: "human" EXACT genbank_common_name []
xref: GC_ID:1
is_a: NCBITaxon:9605 ! Homo
property_value: has_rank NCBITaxon:species

[Term]
id: NCBITaxon:9989
name: Rodentia
namespace: ncbi_taxonomy
synonym: "rodent" EXACT genbank_common_name []
synonym: "rodents" RELATED blast_name []
xref: GC_ID:1
is_a: NCBITaxon:314147 ! Glires
property_value: has_rank NCBITaxon:order

[Term]
id: OBI:0000011
name: planned process
def: "A process that realizes a plan which is the concretization of a plan specification." []
is_a: BFO:0000015 ! process
property_value: IAO:0000111 "planned process" xsd:string
property_value: IAO:0000412 http://purl.obolibrary.org/obo/obi.owl

[Term]
id: OBI:0100026
name: organism
namespace: obi
comment: Category=external.
is_a: BFO:0000030 ! object

[Term]
id: PATO:0000001
name: quality
namespace: quality
alt_id: PATO:0000072
def: "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" [PATOC:GVG]
is_a: BFO:0000020 ! characteristic

[Term]
id: PATO:0000025
name: composition
namespace: quality
alt_id: PATO:0002015
def: "A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts." [PATOC:GVG]
comment: For example calcium composition (which may inhere in bone), haemoglobin composition (which may inhere in blood).
subset: attribute_slim
subset: scalar_slim
synonym: "composed of" EXACT []
synonym: "compositionality" EXACT []
synonym: "content" EXACT []
synonym: "structure, composition" EXACT []
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0000039
name: direction
namespace: quality
def: "A physical quality inhering in a bearer by virtue of the bearer's orientation in space." []
def: "A physical quality inhering in a bearer by virtue of the bearer's orientation in space." [thesaurus.maths:thesaurus.maths]
comment: TODO: consider merging with angular placement.
subset: attribute_slim
is_a: PATO:0001018 ! physical quality

[Term]
id: PATO:0000040
name: distance
namespace: quality
def: "A quality that is the extent of space between two entities." [PATOC:GVG]
subset: attribute_slim
subset: relational_slim
subset: scalar_slim
is_a: PATO:0001018 ! physical quality

[Term]
id: PATO:0000051
name: morphology
namespace: quality
def: "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0001241 ! physical object quality
property_value: IAO:0000111 "morphology" xsd:string
property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl

[Term]
id: PATO:0000052
name: shape
namespace: quality
alt_id: PATO:0001647
def: "A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc)." [PATOC:GVG]
comment: Shapes are invariant on size transformations. Shapes can be subdivided into 2D and 3D shapes, We can also make a distinction between shapes of complete self-connected objects, and shapes of parts of objects.
subset: attribute_slim
synonym: "relational shape quality" EXACT []
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000060
name: spatial pattern
namespace: quality
alt_id: PATO:0000132
alt_id: PATO:0001565
def: "A spatial quality inhering in a bearer by virtue of the bearer's exhibiting repetition of placement of its parts." [PATOC:GVG]
subset: attribute_slim
subset: hpo_slim
synonym: "distribution" EXACT []
synonym: "pattern" RELATED []
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000068
name: qualitative
namespace: quality
comment: TODO: define this or obsolete it and move children somewhere else.
is_a: PATO:0000001 ! quality

[Term]
id: PATO:0000069
name: deviation (from_normal)
namespace: quality
def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0000068 ! qualitative

[Term]
id: PATO:0000070
name: amount
namespace: quality
alt_id: PATO:0000053
alt_id: PATO:0000071
alt_id: PATO:0001169
alt_id: PATO:0001226
def: "The number of entities of this type that are part of the whole organism." [PATOC:GVG]
comment: This term was originally named "presence". It has been renamed to reduce ambiguity. Consider annotating with the reciprocal relation,PATO:0001555, has_number_of. For example, rather than E=fin ray Q=count in organism C=10, say E=organism Q=has number of E2= fin ray C=10.
subset: attribute_slim
synonym: "count in organism" RELATED []
synonym: "number" RELATED []
synonym: "presence" RELATED []
synonym: "presence or absence in organism" EXACT []
synonym: "quantitative" EXACT []
is_a: PATO:0000068 ! qualitative
relationship: RO:0015012 PATO:0001555 ! has number of

[Term]
id: PATO:0000117
name: size
namespace: quality
def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet]
subset: attribute_slim
subset: scalar_slim
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000136
name: closure
namespace: quality
def: "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent." [PATOC:CJM, PATOC:GVG]
subset: attribute_slim
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000141
name: structure
namespace: quality
alt_id: PATO:0001452
def: "A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form." [PATOC:GVG]
subset: attribute_slim
synonym: "conformation" BROAD [VT:1000738]
synonym: "relational structural quality" EXACT []
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000150
name: texture
namespace: quality
def: "A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0000051 ! morphology

[Term]
id: PATO:0000261
name: maturity
namespace: quality
def: "A quality of a single physical entity which is held by a bearer when the latter exhibits a state of growth, differentiation, or development." [Merriam-Webster:Merriam-Webster]
subset: attribute_slim
is_a: PATO:0001995 ! organismal quality

[Term]
id: PATO:0000365
name: down
namespace: quality
def: "A directional quality inhering in a bearer by virtue of the bearer's direction from a higher to a lower point." []
def: "A directional quality inhering in a bearer by virtue of the bearer's direction from a higher to a lower point." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000039 ! direction
property_value: RO:0002604 PATO:0000370

[Term]
id: PATO:0000374
name: increased distance
namespace: quality
def: "A distance which is greater relative to the normal or average." [PATOC:GVG]
subset: relational_slim
subset: value_slim
synonym: "long distance" RELATED []
is_a: PATO:0000040 ! distance
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000040 ! distance
intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal
property_value: RO:0002604 PATO:0000375

[Term]
id: PATO:0000375
name: decreased distance
namespace: quality
def: "A distance which is lesser relative to the normal or average." [PATOC:GVG]
subset: relational_slim
subset: value_slim
synonym: "short distance" RELATED []
is_a: PATO:0000040 ! distance
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000040 ! distance
intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal
property_value: RO:0002604 PATO:0000374

[Term]
id: PATO:0000402
name: branched
namespace: quality
def: "A branchiness quality inhering in a bearer by virtue of the bearer's having branches." [WordNet:WordNet]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "ramified" EXACT []
synonym: "ramiform" EXACT []
is_a: PATO:0002009 ! branchiness
property_value: RO:0002604 PATO:0000414

[Term]
id: PATO:0000404
name: coiled
namespace: quality
alt_id: PATO:0001363
def: "A shape quality inhering in a bearer by virtue of the bearer's being curled or wound (especially in concentric rings or spirals)." [WordNet:WordNet]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "helical" RELATED []
synonym: "helicoid" RELATED []
synonym: "helicoidal" RELATED []
synonym: "helix-shaped" RELATED []
synonym: "spiral" EXACT []
is_a: PATO:0001794 ! coiling
property_value: RO:0002604 PATO:0000415

[Term]
id: PATO:0000407
name: flat
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's having a horizontal surface without a slope, tilt, or curvature." [web:http\://www.merriam-webster.com/]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "plate-like" RELATED []
is_a: PATO:0002254 ! flattened

[Term]
id: PATO:0000411
name: circular
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center." [thefreedictionary.com:thefreedictionary.com]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "round" RELATED []
synonym: "rounded" RELATED []
is_a: PATO:0000947 ! elliptic

[Term]
id: PATO:0000461
name: normal
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG]
subset: abnormal_slim
subset: mpath_slim
subset: value_slim
synonym: "average" RELATED []
is_a: PATO:0000068 ! qualitative
property_value: RO:0002604 PATO:0000460

[Term]
id: PATO:0000467
name: present
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's existence." [PATOC:GVG]
subset: absent_slim
subset: value_slim
synonym: "present in organism" RELATED []
is_a: PATO:0000070 ! amount
property_value: RO:0002604 PATO:0000462

[Term]
id: PATO:0000470
name: increased amount
namespace: quality
alt_id: PATO:0000420
alt_id: PATO:0000650
def: "An amount which is relatively high." [PATOC:GVG]
subset: value_slim
synonym: "accessory" RELATED []
synonym: "increased" RELATED []
synonym: "increased number" EXACT []
synonym: "present in greater numbers in organism" EXACT []
synonym: "supernumerary" EXACT []
is_a: PATO:0000467 ! present
is_a: PATO:0002300 ! increased quality
intersection_of: PATO:0000070 ! amount
intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal
property_value: RO:0002604 PATO:0001997

[Term]
id: PATO:0000586
name: increased size
namespace: quality
alt_id: PATO:0001202
def: "A size quality which is relatively high." [PATOC:GVG]
subset: value_slim
synonym: "big" RELATED []
synonym: "enlarged" RELATED []
synonym: "expanded" RELATED []
synonym: "great" RELATED []
synonym: "large" RELATED []
is_a: PATO:0000117 ! size
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000117 ! size
intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal
property_value: RO:0002604 PATO:0000587

[Term]
id: PATO:0000587
name: decreased size
namespace: quality
def: "A size quality which is relatively low." [PATOC:GVG]
subset: value_slim
synonym: "hypoplasia" NARROW []
synonym: "reduced" RELATED []
synonym: "small" RELATED []
synonym: "tiny" RELATED []
synonym: "underdeveloped" NARROW []
is_a: PATO:0000117 ! size
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000117 ! size
intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal
property_value: RO:0002604 PATO:0000586

[Term]
id: PATO:0000591
name: increased thickness
namespace: quality
def: "A thickness which is relatively high." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "high thickness" EXACT []
synonym: "stout" EXACT []
synonym: "thick" RELATED []
synonym: "thickened" EXACT []
is_a: PATO:0000586 ! increased size
is_a: PATO:0000915 ! thickness
intersection_of: PATO:0000915 ! thickness
intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal
property_value: RO:0002604 PATO:0000592

[Term]
id: PATO:0000592
name: decreased thickness
namespace: quality
def: "A thickness which is relatively low." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "low thickness" EXACT []
synonym: "slender" RELATED []
synonym: "thin" RELATED []
is_a: PATO:0000587 ! decreased size
is_a: PATO:0000915 ! thickness
intersection_of: PATO:0000915 ! thickness
intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal
property_value: RO:0002604 PATO:0000591

[Term]
id: PATO:0000608
name: closed
namespace: quality
def: "A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view." [answers.com:answers.com]
subset: value_slim
synonym: "blocked" RELATED []
is_a: PATO:0000136 ! closure
property_value: RO:0002604 PATO:0000610

[Term]
id: PATO:0000915
name: thickness
namespace: quality
def: "A 1-D extent quality which is equal to the dimension through an object as opposed to its length or width." [WordNet:WordNet]
comment: Thickness often refers to the smallest 1-D extent compared to the other two orthogonal dimensions, however, this is not always true. See https://github.com/pato-ontology/pato/issues/337 for full discussion.
subset: attribute_slim
subset: scalar_slim
is_a: PATO:0001708 ! 1-D extent
property_value: seeAlso "https://github.com/pato-ontology/pato/issues/337" xsd:string

[Term]
id: PATO:0000944
name: sharpness
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's having a sharp or tapered end or point." [PATOC:GVG]
subset: attribute_slim
subset: cell_quality
synonym: "apiculate" EXACT []
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0000947
name: elliptic
namespace: quality
def: "A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section." [PATOC:GVG]
subset: cell_quality
subset: mpath_slim
subset: value_slim
synonym: "ellipse-shaped" EXACT []
synonym: "ellipsoid" EXACT []
synonym: "elliptical" EXACT []
synonym: "oval" RELATED []
synonym: "ovoid" RELATED []
is_a: PATO:0002318 ! superelliptic

[Term]
id: PATO:0000957
name: opacity
namespace: quality
def: "An optical quality which obtains by virtue of the ability of the bearer to absorb visible light." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0001300 ! optical quality

[Term]
id: PATO:0000963
name: opaque
namespace: quality
def: "A optical quality inhering in a bearer by virtue of the bearer's not being clear; not transmitting or reflecting light or radiant energy." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "clouding" RELATED []
synonym: "cloudy" RELATED []
synonym: "non-transparent" EXACT []
is_a: PATO:0000957 ! opacity
property_value: RO:0002604 PATO:0000964

[Term]
id: PATO:0000964
name: transparent
namespace: quality
def: "A optical quality inhering in a bearer by virtue of the bearer's lacking opacity." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
synonym: "clear" EXACT []
synonym: "hyaline" EXACT []
is_a: PATO:0000957 ! opacity
property_value: RO:0002604 PATO:0000963

[Term]
id: PATO:0000965
name: symmetry
namespace: quality
def: "A pattern quality of inhering in a bearer by virtue of the correspondence in size, shape, and relative position of the bearer's parts on opposite sides of a dividing line or median plane or about a center or axis." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0000060 ! spatial pattern

[Term]
id: PATO:0000973
name: porosity
namespace: quality
def: "A structure quality inhering in a bearer by virtue of the bearer's disposition to admit the passage of gas or liquid through pores or interstices." [PATOC:GVG]
subset: attribute_slim
subset: disposition_slim
subset: scalar_slim
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0000984
name: porous
namespace: quality
def: "A porosity quality inhering in a bearer by virtue of the bearer's being capable of admitting the passage of gas or liquid through pores or interstices." [PATOC:GVG]
subset: disposition_slim
subset: value_slim
is_a: PATO:0000973 ! porosity
property_value: RO:0002604 PATO:0000985

[Term]
id: PATO:0000992
name: viscosity
namespace: quality
def: "A physical quality of a fluid inhering in a bearer by virtue of the bearer's disposition to internal resistance to flow." [PATOC:GVG]
subset: attribute_slim
subset: disposition_slim
is_a: PATO:0001548 ! quality of a liquid

[Term]
id: PATO:0000998
name: viscous
namespace: quality
def: "A viscosity quality inhering in a bearer by virtue of the bearer's having viscosity." [PATOC:GVG]
subset: disposition_slim
subset: mpath_slim
subset: value_slim
is_a: PATO:0000992 ! viscosity

[Term]
id: PATO:0001018
name: physical quality
namespace: quality
alt_id: PATO:0002079
def: "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." [PATOC:GVG]
subset: attribute_slim
synonym: "relational physical quality" EXACT []
xref: Wikipedia:Physical_property
is_a: PATO:0001241 ! physical object quality

[Term]
id: PATO:0001031
name: elasticity
namespace: quality
def: "A physical quality inhering in a bearer by virtue of the bearer's disposition to recover its size and shape after deformation in any way." [merriam-webster:merriam-webster]
subset: attribute_slim
subset: disposition_slim
subset: scalar_slim
is_a: PATO:0001018 ! physical quality

[Term]
id: PATO:0001154
name: elongated
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's length being notably higher than its width." [WordNet:WordNet]
subset: value_slim
is_a: PATO:0000052 ! shape
property_value: RO:0002604 PATO:0002364

[Term]
id: PATO:0001171
name: elastic
namespace: quality
def: "An elasticity quality inhering in a bearer by virtue of the bearer's ability to recover its size and shape after deformation in any way." [merriam-webster:merriam-webster]
subset: disposition_slim
subset: mpath_slim
subset: value_slim
is_a: PATO:0001031 ! elasticity
property_value: RO:0002604 PATO:0001172

[Term]
id: PATO:0001185
name: larval
namespace: quality
def: "A maturity quality inhering in a bearer by virtue of the bearer's indirect development, undergoing metamorphosis." [Wikipedia:http\://en.wikipedia.org/wiki/Larval]
subset: value_slim
is_a: PATO:0000261 ! maturity

[Term]
id: PATO:0001190
name: juvenile
namespace: quality
def: "A maturity quality inhering in a bearer by virtue the bearer's being not fully grown or developed." [thefreedictionary.com:thefreedictionary.com]
subset: mpath_slim
subset: value_slim
is_a: PATO:0000261 ! maturity

[Term]
id: PATO:0001199
name: linear
def: "A shape quality inhering in a bearer by virtue of the bearer's being narrow, with the two opposite margins parallel." [ISBN:0881923214]
is_a: PATO:0000001 ! quality

[Term]
id: PATO:0001241
name: physical object quality
namespace: quality
alt_id: PATO:0001237
alt_id: PATO:0001238
def: "A quality which inheres in a continuant." [PATOC:GVG]
comment: Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles.
synonym: "monadic quality of a continuant" EXACT []
synonym: "monadic quality of an object" NARROW []
synonym: "monadic quality of continuant" NARROW []
synonym: "multiply inhering quality of a physical entity" EXACT []
synonym: "quality of a continuant" EXACT []
synonym: "quality of a single physical entity" EXACT []
synonym: "quality of an object" EXACT []
synonym: "quality of continuant" EXACT []
xref: snap:Quality
is_a: BFO:0000019 ! quality
is_a: PATO:0000001 ! quality
property_value: IAO:0000111 "physical object quality" xsd:string
property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl

[Term]
id: PATO:0001300
name: optical quality
namespace: quality
def: "An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0070060 ! quality of interaction of a substance with electromagnetic radiation

[Term]
id: PATO:0001355
name: convex
namespace: quality
def: "A shape quality that obtains by virtue of the bearer having inward facing edges; having a surface or boundary that curves or bulges outward, as the exterior of a sphere." [PATOC:GVG]
subset: cell_quality
subset: value_slim
is_a: PATO:0002005 ! concavity
property_value: RO:0002604 PATO:0001857

[Term]
id: PATO:0001369
name: raised
namespace: quality
def: "A shape quality inhering in a colony by virtue of the bearer's appearing above the medium surface with terraced edges." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0001374
name: ploidy
namespace: quality
def: "A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism." [Wikipedia:http\://en.wikipedia.org/wiki/Ploidy]
subset: attribute_slim
is_a: PATO:0001396 ! cellular quality

[Term]
id: PATO:0001375
name: haploid
namespace: quality
def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Haploid]
subset: cell_quality
subset: value_slim
is_a: PATO:0001393 ! euploid

[Term]
id: PATO:0001377
name: polyploid
namespace: quality
def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Polyploid]
subset: cell_quality
subset: value_slim
is_a: PATO:0001393 ! euploid

[Term]
id: PATO:0001393
name: euploid
namespace: quality
def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Euploid]
subset: cell_quality
subset: value_slim
is_a: PATO:0001374 ! ploidy

[Term]
id: PATO:0001394
name: diploid
namespace: quality
def: "A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father." [Wikipedia:http\://en.wikipedia.org/wiki/Diploid]
comment: The exact number may be one or two different from the 2n number and still be classified as diploidy (although with aneuploidy). Nearly all mammals are diploid organisms, although all individuals have some small fraction of cells that are polyploidy.
subset: cell_quality
subset: value_slim
is_a: PATO:0001393 ! euploid

[Term]
id: PATO:0001396
name: cellular quality
namespace: quality
def: "A monadic quality of continuant that exists at the cellular level of organisation." [PATOC:GVG]
is_a: PATO:0070044 ! anatomical structure quality

[Term]
id: PATO:0001397
name: cellular potency
namespace: quality
def: "A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types." [PATOC:GVG]
subset: attribute_slim
subset: disposition_slim
is_a: PATO:0001396 ! cellular quality

[Term]
id: PATO:0001400
name: unipotent
namespace: quality
def: "A cellular potency that is the capacity to produce only one differentiated cell type." [Wikipedia:http\://en.wikipedia.org/wiki/Unipotent]
comment: Unipotent cells have the quality of self-renewal which distinguishes them from non-stem cells.
subset: cell_quality
subset: disposition_slim
subset: value_slim
is_a: PATO:0001397 ! cellular potency

[Term]
id: PATO:0001401
name: oligopotent
namespace: quality
def: "A cellular potency that is the capacity to form multiple differentiated cell types of a specific lineage and lack self renewing capacity." [PATOC:MAH]
comment: Less potent than multipotent, often thought of as precursor or progenitor cell status.
subset: cell_quality
subset: disposition_slim
subset: value_slim
is_a: PATO:0001397 ! cellular potency

[Term]
id: PATO:0001402
name: multipotent
namespace: quality
def: "A cellular potency that is the capacity to form multiple differentiated cell types." [Wikipedia:http\://en.wikipedia.org/wiki/Multipotent]
subset: cell_quality
subset: disposition_slim
subset: value_slim
is_a: PATO:0001397 ! cellular potency

[Term]
id: PATO:0001404
name: nucleate quality
namespace: quality
def: "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0001396 ! cellular quality

[Term]
id: PATO:0001405
name: anucleate
namespace: quality
def: "A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus." [Biology-online:Biology-online]
subset: cell_quality
subset: mpath_slim
subset: value_slim
is_a: PATO:0001404 ! nucleate quality

[Term]
id: PATO:0001406
name: binucleate
namespace: quality
def: "A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei." [Biology-online:Biology-online]
subset: cell_quality
subset: mpath_slim
subset: value_slim
is_a: PATO:0001908 ! multinucleate

[Term]
id: PATO:0001407
name: mononucleate
namespace: quality
def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus." [Biology-online:Biology-online]
subset: cell_quality
subset: mpath_slim
subset: value_slim
is_a: PATO:0002505 ! nucleated

[Term]
id: PATO:0001408
name: ciliatedness
namespace: quality
def: "A cellular quality inhering in a bearer by virtue of the bearer's having thin, tail-like projections extending outwards from the cell body." [Wikipedia:http\://en.wikipedia.org/wiki/Ciliated]
subset: cell_quality
subset: value_slim
is_a: PATO:0001396 ! cellular quality

[Term]
id: PATO:0001410
name: striated
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel." [Biology-online:Biology-online]
subset: cell_quality
subset: mpath_slim
subset: value_slim
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0001419
name: sharp
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's terminating in a point or edge." [PATOC:GVG]
subset: cell_quality
subset: value_slim
is_a: PATO:0000944 ! sharpness

[Term]
id: PATO:0001500
name: tapered
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being gradually narrower or thinner toward one end." [WordNet:WordNet]
subset: cell_quality
subset: value_slim
synonym: "taper" EXACT []
is_a: PATO:0001419 ! sharp

[Term]
id: PATO:0001501
name: immature
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's lacking complete growth, differentiation, or development." [Merriam-Webster:Merriam-Webster]
subset: value_slim
synonym: "underdeveloped" RELATED []
is_a: PATO:0000261 ! maturity
property_value: RO:0002604 PATO:0001701

[Term]
id: PATO:0001543
name: flexibility
namespace: quality
def: "A physical quality inhering in a bearer by virtue of the bearer's disposition to being turned, bowed, or twisted without breaking." [merriam-webster:merriam-webster]
subset: attribute_slim
subset: disposition_slim
is_a: PATO:0001546 ! quality of a solid

[Term]
id: PATO:0001546
name: quality of a solid
namespace: quality
def: "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable." [Chemistry:http\://chemistry.about.com/od/chemistryglossary/a/soliddefinition.htm]
subset: attribute_slim
synonym: "solidity" EXACT []
is_a: PATO:0002198 ! quality of a substance

[Term]
id: PATO:0001547
name: quality of a gas
namespace: quality
def: "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape." [Chemistry:http\://chemistry.about.com/od/chemistryglossary/a/gasdefinition.htm, PATOC:GVG]
subset: attribute_slim
synonym: "gaseous" EXACT []
is_a: PATO:0002198 ! quality of a substance

[Term]
id: PATO:0001548
name: quality of a liquid
namespace: quality
def: "A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape." [url:http\://www.chemistry-dictionary.com/definition/liquid.php]
subset: attribute_slim
synonym: "liquidity" EXACT []
is_a: PATO:0002198 ! quality of a substance

[Term]
id: PATO:0001555
name: has number of
namespace: quality
def: "The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts." [PATOC:CJM]
subset: attribute_slim
subset: relational_slim
synonym: "cardinality" RELATED []
synonym: "extra or missing physical or functional parts" EXACT []
synonym: "has or lacks parts of type" EXACT []
synonym: "mereological quality" EXACT []
synonym: "number" RELATED []
synonym: "number of" EXACT []
xref: OBO_REL:has_part
is_a: PATO:0001241 ! physical object quality
relationship: RO:0015012 PATO:0000070 ! amount

[Term]
id: PATO:0001571
name: dilated
namespace: quality
def: "A size quality inhering in a bearer by virtue of the bearer's being made wider or larger in all dimensions." [WordNet:WordNet]
def: "A size quality inhering in a bearer by virtue of the bearer's being made wider or larger in all dimensions. [database_cross_reference: WordNet:WordNet]" []
subset: mpath_slim
subset: value_slim
is_a: PATO:0000586 ! increased size

[Term]
id: PATO:0001573
name: isometrical
namespace: quality
def: "A symmetry quality inhering in a bearer by virtue of the bearer's having equal dimensions or measurements." [WordNet:WordNet]
def: "A symmetry quality inhering in a bearer by virtue of the bearer's having equal dimensions or measurements." []
subset: cell_quality
subset: value_slim
is_a: PATO:0000965 ! symmetry

[Term]
id: PATO:0001579
name: contractility
namespace: quality
def: "A physical quality that is the ability to contract or shrink." [WordNet:WordNet]
subset: attribute_slim
subset: disposition_slim
subset: scalar_slim
is_a: PATO:0001018 ! physical quality

[Term]
id: PATO:0001591
name: curvature
namespace: quality
def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet]
subset: attribute_slim
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0001690
name: contractile
namespace: quality
def: "A contractility quality inhering in a bearer by virtue of the bearer's ability of contracting or being contracted." [PATOC:GVG]
comment: This refers to the disposition of the bearer.
subset: disposition_slim
subset: value_slim
is_a: PATO:0001579 ! contractility
property_value: RO:0002604 PATO:0001691

[Term]
id: PATO:0001708
name: 1-D extent
namespace: quality
def: "A size quality inhering in an bearer by virtue of the bearer's extension in one dimension." [PATOC:GVG]
subset: attribute_slim
synonym: "1-D size" EXACT []
is_a: PATO:0000117 ! size

[Term]
id: PATO:0001735
name: liquid configuration
namespace: quality
def: "A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of liquids." [PATOC:GVG]
synonym: "liquid" EXACT []
is_a: PATO:0001548 ! quality of a liquid

[Term]
id: PATO:0001736
name: solid configuration
namespace: quality
def: "A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of solids." [PATOC:GVG]
subset: value_slim
synonym: "solid" EXACT []
is_a: PATO:0001546 ! quality of a solid

[Term]
id: PATO:0001748
name: invaginated
namespace: quality
def: "A shape quality in which a portion of the outermost boundary of an entity folds in space such that a portion that was originally convex is now concave." [PATOC:GVG]
subset: cell_quality
subset: mpath_slim
subset: value_slim
is_a: PATO:0001857 ! concave

[Term]
id: PATO:0001794
name: coiling
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being wound in a continuous series of loops." [Online_Dictionary:Online_Dictionary]
subset: attribute_slim
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0001795
name: increased coiling
namespace: quality
def: "A coiling which is relatively high." [PATOC:GVG]
subset: cell_quality
subset: value_slim
synonym: "high coiling" EXACT []
is_a: PATO:0000404 ! coiled
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000404 ! coiled
intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal
property_value: RO:0002604 PATO:0001796

[Term]
id: PATO:0001796
name: decreased coiling
namespace: quality
def: "A coiling which is relatively low." [PATOC:GVG]
subset: cell_quality
subset: value_slim
synonym: "low coiling" EXACT []
is_a: PATO:0000404 ! coiled
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000404 ! coiled
intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal
property_value: RO:0002604 PATO:0001795

[Term]
id: PATO:0001847
name: constricted
namespace: quality
alt_id: PATO:0001837
def: "A structural quality inhering in a bearer by virtue of the bearer's being drawn together, compressed or squeezed physically." [WordNet:WordNet]
subset: value_slim
synonym: "stenosis" EXACT []
synonym: "stenotic" EXACT []
synonym: "stricture" EXACT []
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0001857
name: concave
namespace: quality
def: "A shape quality in a bearer by virtue of the bearer's curving inward." [WordNet:WordNet]
subset: cell_quality
subset: value_slim
is_a: PATO:0002005 ! concavity
property_value: RO:0002604 PATO:0001355

[Term]
id: PATO:0001873
name: cylindrical
namespace: quality
alt_id: PATO:0001203
def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section." [PATOC:MAH]
subset: cell_quality
subset: value_slim
synonym: "rod-like" EXACT []
synonym: "rod-shaped" EXACT []
synonym: "tubulate" NARROW []
is_a: PATO:0002007 ! convex 3-D shape
relationship: has_cross_section PATO:0000411 ! circular

[Term]
id: PATO:0001901
name: back
namespace: quality
def: "A directional quality inhering in a bearer by virtue of the bearer's direction that is similar to the direction of an object to the north when it faces south." []
def: "A directional quality inhering in a bearer by virtue of the bearer's direction that is similar to the direction of an object to the north when it faces south." [PATOC:GVG]
subset: value_slim
is_a: PATO:0000039 ! direction
property_value: RO:0002604 PATO:0001900

[Term]
id: PATO:0001908
name: multinucleate
namespace: quality
def: "A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0002505 ! nucleated

[Term]
id: PATO:0001987
name: saccular
namespace: quality
def: "A structural quality inhering in a bearer by virtue of the bearer's having a three dimensional cavity with a narrow or no opening, and often containing an anatomical substance." [PATOC:MAH]
subset: value_slim
synonym: "sacular" EXACT []
is_a: PATO:0002014 ! structure, cavities

[Term]
id: PATO:0001992
name: cellularity
namespace: quality
def: "An organismal quality inhering in a bearer by virtue of the bearer's consisting cells." [PATOC:GVG]
subset: attribute_slim
subset: scalar_slim
is_a: PATO:0001995 ! organismal quality

[Term]
id: PATO:0001993
name: multicellular
namespace: quality
def: "A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell." [PATOC:GVG]
subset: value_slim
is_a: PATO:0001992 ! cellularity

[Term]
id: PATO:0001995
name: organismal quality
namespace: quality
def: "A quality that inheres in an entire organism or part of an organism." [PATOC:CJM]
is_a: PATO:0001241 ! physical object quality

[Term]
id: PATO:0001997
name: decreased amount
namespace: quality
alt_id: PATO:0000419
alt_id: PATO:0000468
def: "An amount which is relatively low." [PATOC:GVG]
subset: value_slim
synonym: "decreased" RELATED []
synonym: "decreased number" EXACT []
synonym: "present in fewer numbers in organism" EXACT []
synonym: "reduced" RELATED []
synonym: "subnumerary" RELATED []
is_a: PATO:0000467 ! present
is_a: PATO:0002301 ! decreased quality
intersection_of: PATO:0000070 ! amount
intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal
property_value: RO:0002604 PATO:0000470

[Term]
id: PATO:0002005
name: concavity
namespace: quality
def: "Surface shape that refers to the inward or outward curvature of the surface." [PATOC:MAH]
subset: attribute_slim
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0002006
name: 2-D shape
namespace: quality
def: "A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity." [PATOC:CJM]
subset: attribute_slim
synonym: "2-D projection" RELATED []
synonym: "cross-sectional" RELATED []
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0002007
name: convex 3-D shape
namespace: quality
def: "A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave." [PATOC:CJM]
comment: Use this term or an is_a child of this term when the entire shape of the object is known.
subset: attribute_slim
xref: Image:http\://upload.wikimedia.org/wikipedia/commons/0/06/Convex_polygon_illustration1.png
is_a: PATO:0002266 ! 3-D shape
relationship: has_cross_section PATO:0002006 ! 2-D shape
property_value: RO:0002604 PATO:0002008

[Term]
id: PATO:0002009
name: branchiness
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity." [PATOC:MAH]
subset: attribute_slim
subset: cell_quality
is_a: PATO:0000052 ! shape

[Term]
id: PATO:0002014
name: structure, cavities
namespace: quality
def: "A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0002021
name: conical
namespace: quality
def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's resembling a cone (a 3-D shape with a round cross section that tapers)." [Wikipedia:http\://en.wikipedia.org/wiki/Cone_(geometry)]
subset: value_slim
synonym: "cone-shaped" EXACT []
xref: Image:http\://upload.wikimedia.org/wikipedia/commons/d/d2/Cone_3d.png
is_a: PATO:0002007 ! convex 3-D shape

[Term]
id: PATO:0002039
name: biconcave
namespace: quality
def: "A concave quality inhering in a bearer by virtue of the bearer's curving inward on both sides or surfaces." [PATOC:GVG]
subset: value_slim
is_a: PATO:0001857 ! concave
property_value: RO:0002604 PATO:0002040

[Term]
id: PATO:0002045
name: dendritic
namespace: quality
def: "A branched quality inhering in a bearer by virtue of the bearer's having smaller branches arising from larger branches. Resembling a tree in branching structure." [PATOC:cvs]
subset: value_slim
synonym: "dendriform" EXACT []
synonym: "dendroid" EXACT []
synonym: "dendroidal" EXACT []
is_a: PATO:0000402 ! branched
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2009-02-15T08:11:41Z

[Term]
id: PATO:0002078
name: hollow
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's having an empty space or cavity within." [url:http\://www.merriam-webster.com/dictionary/hollow]
subset: value_slim
is_a: PATO:0002014 ! structure, cavities
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2009-09-18T02:19:20Z

[Term]
id: PATO:0002094
name: basophilic
namespace: quality
def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for basic dyes under specific pH conditions." [PATOC:GVG]
subset: disposition_slim
subset: mpath_slim
subset: value_slim
is_a: PATO:0070045 ! anatomical histological quality
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2009-10-05T12:05:23Z

[Term]
id: PATO:0002124
name: laminar
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0000141 ! structure
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2009-10-06T04:37:14Z

[Term]
id: PATO:0002198
name: quality of a substance
namespace: quality
def: "A quality inhering in a bearer by virtue of its constitution." [PATOC:GVG]
subset: attribute_slim
is_a: PATO:0001018 ! physical quality
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2010-03-15T04:35:27Z

[Term]
id: PATO:0002219
name: fan-shaped
namespace: quality
def: "A quality inhering in a bearer that is shaped in the form of a fan." [thefreedictionary:http\://www.thefreedictionary.com/fan-shaped]
subset: value_slim
synonym: "fan-like" EXACT []
is_a: PATO:0002006 ! 2-D shape
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2010-07-09T01:43:42Z

[Term]
id: PATO:0002226
name: subcylindrical
namespace: quality
def: "A cylindrical shape quality inhering in a bearer by virtue of the bearer's being imperfectly cylindrical or approximately cylindrical." [url:http\://www.thefreedictionary.com/Subcylindrical]
subset: value_slim
is_a: PATO:0001873 ! cylindrical
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2010-07-13T04:22:30Z

[Term]
id: PATO:0002228
name: acuminate
namespace: quality
def: "A tapered shape quality inhering in a bearer by virtue of the bearer's tapering gradually to a sharp point." [url:http\://www.thefreedictionary.com/acuminate]
subset: value_slim
is_a: PATO:0001500 ! tapered
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2010-07-15T09:03:18Z

[Term]
id: PATO:0002254
name: flattened
namespace: quality
def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS]
comment: Becoming flat but not necessarily completely flat.
subset: value_slim
synonym: "compressed" RELATED []
is_a: PATO:0001591 ! curvature
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2010-08-16T03:59:34Z

[Term]
id: PATO:0002255
name: grooved
namespace: quality
def: "Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels." [PATOC:JE]
subset: value_slim
synonym: "channeled" RELATED []
synonym: "creased" RELATED []
is_a: PATO:0000150 ! texture
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2010-09-01T10:27:48Z

[Term]
id: PATO:0002266
name: 3-D shape
namespace: quality
def: "A shape that inheres in a 3 dimensional entity." [PATOC:OREGON]
is_a: PATO:0000052 ! shape
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2010-10-05T12:31:16Z

[Term]
id: PATO:0002287
name: increased elasticity
namespace: quality
def: "An elasticity which is relatively high." [PATOC:GVG]
subset: value_slim
is_a: PATO:0001171 ! elastic
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0001171 ! elastic
intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
property_value: RO:0002604 PATO:0002288
creation_date: 2011-03-30T11:50:21Z

[Term]
id: PATO:0002288
name: decreased elasticity
namespace: quality
def: "An elasticity which is relatively low." [PATOC:GVG]
subset: value_slim
is_a: PATO:0001171 ! elastic
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0001171 ! elastic
intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
property_value: RO:0002604 PATO:0002287
creation_date: 2011-03-30T11:50:39Z

[Term]
id: PATO:0002299
name: tubular
namespace: quality
def: "A cylindrical shape that is hollow." [PATOC:GVG]
synonym: "tube like" EXACT []
synonym: "tube-shaped" EXACT []
synonym: "tubulate" EXACT []
is_a: PATO:0001873 ! cylindrical
is_a: PATO:0002078 ! hollow
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2011-06-08T06:33:50Z

[Term]
id: PATO:0002300
name: increased quality
namespace: quality
def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG]
is_a: PATO:0000069 ! deviation (from_normal)
intersection_of: PATO:0000001 ! quality
intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal
relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
property_value: RO:0002604 PATO:0002301
creation_date: 2011-06-16T06:39:43Z

[Term]
id: PATO:0002301
name: decreased quality
namespace: quality
def: "A quality that has a value that is decreased compared to normal or average." [PATOC:GVG]
is_a: PATO:0000069 ! deviation (from_normal)
intersection_of: PATO:0000001 ! quality
intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal
relationship: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
property_value: RO:0002604 PATO:0002300
creation_date: 2011-06-16T06:40:15Z

[Term]
id: PATO:0002303
name: decreased object quality
namespace: quality
def: "A quality of an object that has a value that is decreased compared to normal or average." [PATOC:GVG]
is_a: PATO:0001241 ! physical object quality
is_a: PATO:0002301 ! decreased quality
intersection_of: PATO:0001241 ! physical object quality
intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
property_value: RO:0002604 PATO:0002305
creation_date: 2011-06-16T06:51:54Z

[Term]
id: PATO:0002305
name: increased object quality
namespace: quality
def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG]
is_a: PATO:0001241 ! physical object quality
is_a: PATO:0002300 ! increased quality
intersection_of: PATO:0001241 ! physical object quality
intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
property_value: RO:0002604 PATO:0002303
creation_date: 2011-06-16T06:54:01Z

[Term]
id: PATO:0002309
name: fiber shaped
namespace: quality
def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter." [PATOC:DC]
comment: Note that a fiber shaped object may take any circuitous or straight path through space (think of a length of string or rope).
subset: value_slim
is_a: PATO:0002226 ! subcylindrical
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2011-09-09T04:50:10Z

[Term]
id: PATO:0002318
name: superelliptic
namespace: quality
def: "A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt" [wiktionary:superellipse]
synonym: "Lamé curve" EXACT []
is_a: PATO:0002006 ! 2-D shape
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2011-10-12T12:45:16Z

[Term]
id: PATO:0002418
name: acidophilic
namespace: quality
def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for acidic dyes under specific pH conditions." [PATOC:GVG]
comment: Eosin stains acidophilic structures, hence eosinophilic is the same as acidophilic.
subset: mpath_slim
subset: value_slim
synonym: "eosinophilic" EXACT []
is_a: PATO:0070045 ! anatomical histological quality
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2012-12-17T03:01:19Z

[Term]
id: PATO:0002422
name: acinar
namespace: quality
def: "Pertaining to the individual parts making up an aggregate fruit like a many-lobed \"berry,\" such as a raspberry." [wikipedia:https\://en.wikipedia.org/wiki/Acinus]
comment: Acinus is Latin for berry.
subset: mpath_slim
subset: value_slim
is_a: PATO:0000141 ! structure
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2012-12-17T03:11:10Z

[Term]
id: PATO:0002462
name: collagenous
namespace: quality
def: "A composition quality inhering in an bearer by virtue of the bearer's consisting of collagen." [PATOC:WD]
subset: value_slim
is_a: PATO:0000025 ! composition
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2013-09-15T11:34:15Z

[Term]
id: PATO:0002468
name: distensible
namespace: quality
def: "A structure quality inhering in a bearer by virtue of the bearer's being capable of swelling or stretching." [PATOC:WD]
subset: value_slim
is_a: PATO:0015008 ! distensibility
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2013-09-15T11:48:26Z

[Term]
id: PATO:0002478
name: transversely striated
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented transversely relative to the long axis of the bearer." [PATOC:DS]
subset: cell_quality
subset: mpath_slim
subset: value_slim
is_a: PATO:0001410 ! striated
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2013-09-15T12:29:15Z

[Term]
id: PATO:0002505
name: nucleated
namespace: quality
def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus." [PATOC:GVG]
subset: mpath_slim
subset: value_slim
is_a: PATO:0001404 ! nucleate quality
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X
creation_date: 2013-10-21T05:44:34Z

[Term]
id: PATO:0002539
name: ring shaped
namespace: quality
def: "A shape quality inhering in a bearer by virtue of the bearer's having a shape like a ring (a circular shape enclosing a space)." [PATOC:WD]
subset: value_slim
synonym: "annular" EXACT []
synonym: "ring-shaped" EXACT []
is_a: PATO:0000947 ! elliptic
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-3162-7490
creation_date: 2014-08-12T12:01:56Z

[Term]
id: PATO:0010001
name: disconnected
namespace: quality
def: "A structural quality inhering in the bearer by virtue of the bearer consisting of multiple structures lacking any physical connection to each other." [GOC:dos]
is_a: PATO:0000141 ! structure
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-7073-9172
creation_date: 2014-12-12T08:43:17Z

[Term]
id: PATO:0015006
name: polymeric
namespace: quality
def: "A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array." [GOC:DOS, https://github.com/pato-ontology/pato/issues/78]
comment: A complete coverage of this domain would subclasses homopolymeric, copolymeric, crystalline.
subset: value_slim
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0015008
name: distensibility
namespace: quality
def: "A quality inhering in a bearer by virtue of the extent to which the bearer is capable of being stretched or swollen." [GOC:CJM]
subset: attribute_slim
is_a: PATO:0000141 ! structure

[Term]
id: PATO:0015024
name: increased porosity
namespace: quality
def: "An increase in porosity." [https://github.com/pato-ontology/pato/issues/110]
subset: value_slim
is_a: PATO:0000973 ! porosity
is_a: PATO:0002305 ! increased object quality
intersection_of: PATO:0000973 ! porosity
intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal

[Term]
id: PATO:0015025
name: decreased porosity
namespace: quality
def: "An decrease in porosity." [https://github.com/pato-ontology/pato/issues/110]
subset: value_slim
is_a: PATO:0000973 ! porosity
is_a: PATO:0002303 ! decreased object quality
intersection_of: PATO:0000973 ! porosity
intersection_of: RO:0015008 PATO:0000461 ! decreased in magnitude relative to normal
property_value: RO:0002604 PATO:0015024

[Term]
id: PATO:0040024
name: bilaterally paired
namespace: quality
def: "The bearer of this quality has_part n=2 of the indicated entity type, where n is unpaired for a comparable organism." [https://orcid.org/0000-0003-3162-7490]
synonym: "paired" BROAD []
is_a: PATO:0000467 ! present
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: PATO:0040072
name: high nuclear/cytoplasmic ratio
namespace: quality
def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284]
comment: A high nuclear/cytolasmic ratio is 70% or higher.
synonym: "high N:C ratio" EXACT []
is_a: PATO:0001396 ! cellular quality
created_by: http://orcid.org/0000-0001-5208-3432

[Term]
id: PATO:0070044
name: anatomical structure quality
namespace: quality
def: "A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components." []
is_a: PATO:0001241 ! physical object quality
created_by: http://orcid.org/0000-0001-7258-9596

[Term]
id: PATO:0070045
name: anatomical histological quality
namespace: quality
def: "A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes." []
is_a: PATO:0070044 ! anatomical structure quality
created_by: http://orcid.org/0000-0001-7258-9596

[Term]
id: PATO:0070046
name: neutrophillic
namespace: quality
def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction that stains and colors, pale-pink, with Wright-Giemsa stain." [GOC:add]
is_a: PATO:0070045 ! anatomical histological quality
created_by: http://orcid.org/0000-0001-7258-9596

[Term]
id: PATO:0070047
name: polychromatophilic
namespace: quality
def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions." [GOC:add]
is_a: PATO:0070045 ! anatomical histological quality
created_by: http://orcid.org/0000-0001-7258-9596

[Term]
id: PATO:0070060
name: quality of interaction of a substance with electromagnetic radiation
namespace: quality
def: "A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength." [https://orcid.org/0000-0002-5111-7263]
subset: attribute_slim
is_a: PATO:0002198 ! quality of a substance

[Term]
id: PR:000000001
name: protein
namespace: protein
def: "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." [PRO:DAN, PRO:WCB]
comment: The definition above excludes protein complexes, which some also consider a protein. Those who wish to refer to a class representing both senses of the word are directed to CHEBI:36080. Note that the definition allows for experimentally-manipulated genes, and allows for artifically-produced derivatives that mimic those found naturally. Proteins (in the sense defined here) that descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB].
synonym: "native protein" NARROW [IEDB:BP]
synonym: "natural protein" EXACT [PRO:DAN]
is_a: PR:000018263 ! amino acid chain
is_a: PR:000050567 ! protein-containing material entity
intersection_of: PR:000018263 ! amino acid chain
intersection_of: has_gene_template SO:0000704 ! gene
intersection_of: output_of GO:0006412 ! translation
relationship: has_gene_template SO:0000704 ! gene
relationship: output_of GO:0006412 ! translation

[Term]
id: PR:000001002
name: CD19 molecule
namespace: protein
def: "A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction." [PMID:15778510]
comment: Category=gene. Requested by=CL.
synonym: "B-lymphocyte surface antigen B4" EXACT []
synonym: "CD19" EXACT PRO-short-label [PRO:DNx]
synonym: "differentiation antigen CD19" EXACT []
synonym: "T-cell surface antigen Leu-12" EXACT []
xref: IUPHARobj:2764
xref: PIRSF:PIRSF016630
is_a: PR:000000001 ! protein

[Term]
id: PR:000001003
name: CD34 molecule
namespace: protein
def: "A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved." [PMID:16720896, PMID:8983065]
comment: Category=gene. Requested by=CL.
synonym: "CD34" EXACT PRO-short-label [PRO:DNx]
synonym: "hematopoietic progenitor cell antigen CD34" EXACT []
xref: PIRSF:PIRSF028749
is_a: PR:000000001 ! protein

[Term]
id: PR:000001004
name: CD4 molecule
namespace: protein
def: "A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence." [PMID:15326605]
comment: Category=gene. Requested by=CL.
synonym: "CD4" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell differentiation antigen L3T4" EXACT []
synonym: "T-cell surface antigen T4/Leu-3" EXACT []
synonym: "T-cell surface glycoprotein CD4" EXACT []
xref: PIRSF:PIRSF001977
is_a: PR:000000001 ! protein

[Term]
id: PR:000001005
name: integrin alpha with A domain
namespace: protein
def: "An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage." [PIRSF:PIRSF002497]
comment: Category=family.
synonym: "integrin alpha with I domain" EXACT []
xref: PIRSF:PIRSF002497
is_a: PR:000025796 ! integrin alpha

[Term]
id: PR:000001012
name: integrin alpha-M
namespace: protein
def: "An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1." [UniProtKB:P11215]
comment: Category=gene. Requested by=CL.
synonym: "CD11 antigen-like family member B" EXACT []
synonym: "CD11B" RELATED Gene-based []
synonym: "CD11b" EXACT []
synonym: "cell surface glycoprotein MAC-1 subunit alpha" EXACT []
synonym: "CR-3 alpha chain" EXACT []
synonym: "CR3A" RELATED Gene-based []
synonym: "ITGAM" EXACT PRO-short-label [PRO:DNx]
synonym: "leukocyte adhesion receptor MO1" EXACT []
synonym: "neutrophil adherence receptor" EXACT []
xref: IUPHARobj:2452
is_a: PR:000001005 ! integrin alpha with A domain
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P11215

[Term]
id: PR:000001018
name: CD3 subunit with immunoglobulin domain
namespace: protein
def: "A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response." [PMID:16473826, PMID:1724736]
comment: Category=family.
synonym: "CD3 subunit with Ig-like domain" EXACT []
xref: PIRSF:PIRSF001993
is_a: PR:000000001 ! protein

[Term]
id: PR:000001020
name: CD3 epsilon
namespace: protein
def: "A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=CL.
synonym: "CD3E" EXACT PRO-short-label [PRO:DNx]
synonym: "CD3e" EXACT []
synonym: "T-cell surface antigen T3/Leu-4 epsilon chain" EXACT []
synonym: "T3E" RELATED Gene-based []
xref: IUPHARobj:2742
is_a: PR:000001018 ! CD3 subunit with immunoglobulin domain

[Term]
id: PR:000001022
name: neural cell adhesion molecule
namespace: protein
def: "A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain." [PRO:CNA]
comment: Category=family.
xref: PIRSF:PIRSF002507
is_a: PR:000000001 ! protein

[Term]
id: PR:000001023
name: neural cell adhesion molecule NCAM
namespace: protein
def: "A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration." [PMID:17975827]
comment: Category=family.
xref: PIRSF:PIRSF501037
is_a: PR:000001022 ! neural cell adhesion molecule

[Term]
id: PR:000001024
name: neural cell adhesion molecule 1
namespace: protein
def: "A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=CL.
synonym: "CD56" EXACT []
synonym: "N-CAM-1" EXACT []
synonym: "NCAM" RELATED Gene-based []
synonym: "NCAM-1" EXACT []
synonym: "NCAM1" EXACT PRO-short-label [PRO:DNx]
xref: IUPHARobj:2769
is_a: PR:000001023 ! neural cell adhesion molecule NCAM
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P13591

[Term]
id: PR:000001083
name: CD2 molecule
namespace: protein
def: "A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=CL.
synonym: "CD2" EXACT PRO-short-label [PRO:DNx]
synonym: "erythrocyte receptor" EXACT []
synonym: "LFA-2" EXACT []
synonym: "LFA-3 receptor" EXACT []
synonym: "ly-37" EXACT []
synonym: "lymphocyte antigen 37" EXACT []
synonym: "rosette receptor" EXACT []
synonym: "SRBC" RELATED Gene-based []
synonym: "T-cell surface antigen CD2" EXACT []
synonym: "T-cell surface antigen T11/Leu-5" EXACT []
synonym: "T-cell surface glycoprotein CD2" EXACT []
xref: IUPHARobj:2600
xref: PIRSF:PIRSF001984
is_a: PR:000000001 ! protein

[Term]
id: PR:000001084
name: T-cell surface glycoprotein CD8 alpha chain
namespace: protein
def: "A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain." [PMID:11114424, PRO:CNA, Wikipedia:CD8]
comment: Category=gene. Requested by=CL.
synonym: "CD8A" EXACT PRO-short-label [PRO:DNx]
synonym: "CD8a" EXACT []
synonym: "Lyt-2" RELATED Gene-based []
synonym: "Lyt2" RELATED Gene-based []
synonym: "MAL" RELATED Gene-based []
synonym: "T-cell surface glycoprotein Lyt-2" EXACT []
synonym: "T-lymphocyte differentiation antigen T8/Leu-2" EXACT []
is_a: PR:000000001 ! protein
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P01732

[Term]
id: PR:000001289
name: membrane-spanning 4-domains subfamily A member 1
namespace: protein
def: "A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "B-cell differentiation antigen Ly-44" EXACT []
synonym: "B-cell surface antigen CD20" EXACT []
synonym: "B-lymphocyte antigen CD20" EXACT []
synonym: "B-lymphocyte surface antigen B1" EXACT []
synonym: "Bp35" EXACT []
synonym: "CD20" RELATED Gene-based []
synonym: "leukocyte surface antigen Leu-16" EXACT []
synonym: "Ly-44" RELATED Gene-based []
synonym: "lymphocyte antigen 44" EXACT []
synonym: "MS4A1" EXACT PRO-short-label [PRO:DNx]
synonym: "Ms4a2" RELATED Gene-based []
xref: IUPHARobj:2628
xref: PIRSF:PIRSF001995
is_a: PR:000000001 ! protein

[Term]
id: PR:000001327
name: cadherin
namespace: protein
def: "A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues." [PRO:WCB]
comment: Category=family.
xref: PIRSF:PIRSF002504
is_a: PR:000000001 ! protein

[Term]
id: PR:000001444
name: cadherin-5
namespace: protein
def: "A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "7B4 antigen" EXACT []
synonym: "CD144" EXACT []
synonym: "CDH5" EXACT PRO-short-label [PRO:DNx]
synonym: "vascular endothelial cadherin" EXACT []
synonym: "VE-cadherin" EXACT []
is_a: PR:000001327 ! cadherin
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P33151

[Term]
id: PR:000001839
name: T-cell surface glycoprotein CD5
namespace: protein
def: "A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "CD5" EXACT PRO-short-label [PRO:DNx]
synonym: "LEU1" RELATED Gene-based []
synonym: "ly-1" EXACT []
synonym: "lymphocyte antigen 1" EXACT []
synonym: "lymphocyte antigen T1/Leu-1" EXACT []
synonym: "Lyt-1" EXACT []
is_a: PR:000000001 ! protein
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P06127

[Term]
id: PR:000001869
name: interleukin-7 receptor subunit alpha
namespace: protein
def: "A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "CD127" EXACT []
synonym: "CDw127" EXACT []
synonym: "IL-7 receptor subunit alpha" EXACT []
synonym: "IL-7R subunit alpha" EXACT []
synonym: "IL-7R-alpha" EXACT []
synonym: "IL-7RA" EXACT []
synonym: "IL7R" EXACT PRO-short-label [PRO:DNx]
xref: IUPHARobj:1698
xref: PIRSF:PIRSF001960
is_a: PR:000000001 ! protein
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P16871

[Term]
id: PR:000001889
name: CD14 molecule
namespace: protein
def: "A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "CD14" EXACT PRO-short-label [PRO:DNx]
synonym: "monocyte differentiation antigen CD14" EXACT []
synonym: "myeloid cell-specific leucine-rich glycoprotein" EXACT []
xref: PIRSF:PIRSF002017
is_a: PR:000000001 ! protein

[Term]
id: PR:000001945
name: transferrin receptor protein 1
namespace: protein
def: "A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "CD71" EXACT []
synonym: "p90" BROAD [PRO:DNx]
synonym: "T9" EXACT []
synonym: "TfR" EXACT []
synonym: "TfR1" EXACT []
synonym: "TFRC" EXACT PRO-short-label [PRO:DNx]
synonym: "TR" RELATED []
synonym: "Trfr" RELATED Gene-based []
is_a: PR:000000001 ! protein
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P02786

[Term]
id: PR:000001971
name: vascular endothelial growth factor receptor
namespace: protein
def: "A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain." [PRO:WCB]
comment: Category=family.
xref: PIRSF:PIRSF038502
is_a: PR:000000001 ! protein

[Term]
id: PR:000002112
name: vascular endothelial growth factor receptor 2
namespace: protein
def: "A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "CD309" EXACT []
synonym: "fetal liver kinase 1" EXACT []
synonym: "FLK-1" EXACT []
synonym: "FLK1" RELATED Gene-based []
synonym: "KDR" EXACT PRO-short-label [PRO:DNx]
synonym: "kinase insert domain receptor" EXACT []
synonym: "kinase NYK" EXACT []
synonym: "protein-tyrosine kinase receptor flk-1" EXACT []
synonym: "VEGFR-2" EXACT []
synonym: "VEGFR2" RELATED Gene-based []
xref: IUPHARobj:1813
is_a: PR:000001971 ! vascular endothelial growth factor receptor
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P35968

[Term]
id: PR:000002976
name: Ly-6-like protein
namespace: protein
def: "A protein that is the translation product of any of the LY6 genes (LY6A-LY6I)." [PRO:CNA]
comment: Category=family.
xref: PIRSF:PIRSF002021
is_a: PR:000000001 ! protein

[Term]
id: PR:000002978
name: lymphocyte antigen 6G
namespace: protein
def: "An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=CL.
synonym: "Ly-6G" EXACT []
synonym: "Ly-6G.1" EXACT []
synonym: "Ly6g" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002976 ! Ly-6-like protein

[Term]
id: PR:000002981
name: lymphocyte antigen 76 (mouse)
namespace: protein
def: "A protein that is a translation product of the Ly76 gene in mouse." [PMID:10848813, PRO:DAN]
comment: Category=organism-gene. Requested by=CL.
synonym: "mLy76" EXACT PRO-short-label [PRO:DNx]
synonym: "ter-119" EXACT []
synonym: "ter119" EXACT []
is_a: PR:000029032 ! Mus musculus protein

[Term]
id: PR:000007499
name: fibroblast growth factor 8
namespace: protein
def: "A protein that is a translation product of the human FGF8 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "AIGF" RELATED Gene-based []
synonym: "androgen-induced growth factor" EXACT []
synonym: "FGF-8" EXACT []
synonym: "FGF8" EXACT PRO-short-label [PRO:DNx]
synonym: "HBGF-8" RELATED []
synonym: "heparin-binding growth factor 8" RELATED []
is_a: PR:000000001 ! protein
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P55075

[Term]
id: PR:000009054
name: insulin gene translation product
namespace: protein
def: "An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "INS" EXACT PRO-short-label [PRO:DNx]
synonym: "insulin" BROAD [PRO:DAN]
is_a: PR:000045358 ! insulin family protein
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P01308

[Term]
id: PR:000014841
name: sonic hedgehog protein
namespace: protein
def: "A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HHG-1" EXACT []
synonym: "Hhg1" RELATED Gene-based []
synonym: "SHH" EXACT PRO-short-label [PRO:DNx]
synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains" EXACT []
synonym: "ShhNC" EXACT []
is_a: PR:000000001 ! protein
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:Q15465

[Term]
id: PR:000016043
name: T-cell acute lymphocytic leukemia protein 1
namespace: protein
def: "A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Requested by=CL.
synonym: "BHLHA17" RELATED Gene-based []
synonym: "bHLHa17" EXACT []
synonym: "class A basic helix-loop-helix protein 17" EXACT []
synonym: "SCL" RELATED Gene-based []
synonym: "stem cell protein" EXACT []
synonym: "T-cell leukemia/lymphoma protein 5" EXACT []
synonym: "TAL-1" EXACT []
synonym: "TAL1" EXACT PRO-short-label [PRO:DNx]
synonym: "TCL5" RELATED Gene-based []
is_a: PR:000000001 ! protein
property_value: https://w3id.org/semapv/vocab/crossSpeciesExactMatch PR:P17542

[Term]
id: PR:000018263
name: amino acid chain
namespace: protein
def: "An organic amino compound that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds." [PRO:DAN, PRO:JSG]
comment: Category=polymer.
synonym: "peptide" NARROW [PRO:DAN]
synonym: "polypeptide" NARROW [PRO:DAN]
is_a: CHEBI:50047 ! organic amino compound
relationship: has_constituent_monomer CHEBI:33708 {minCardinality="2"} ! amino-acid residue

[Term]
id: PR:000025796
name: integrin alpha
namespace: protein
def: "A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif." [PMID:19693543]
comment: Category=family. Integrins are heterodimeric complexes of an alpha and a beta subunit. They are a structurally elaborate family of adhesion molecules that transmit signals bidirectionally across the plasma membrane by undergoing large-scale structural rearrangements. By regulating cell-cell and cell-matrix contacts, integrins participate in a wide-range of biological interactions including development, tissue repair, angiogenesis, inflammation and hemostasis. [PMID:10402956, PMID:11988479, PMID:9676575].
is_a: PR:000000001 ! protein

[Term]
id: PR:000029032
name: Mus musculus protein
namespace: protein
def: "A protein that is encoded in the genome of Mus musculus." [PRO:DAN]
synonym: "mouse protein" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000036194 ! eukaryotic protein
intersection_of: PR:000000001 ! protein
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000029060
name: Drosophila melanogaster protein
namespace: protein
def: "A protein that is encoded in the genome of Drosophila melanogaster." [PRO:DAN]
synonym: "fruit fly protein" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000036194 ! eukaryotic protein
intersection_of: PR:000000001 ! protein
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:000029067
name: Homo sapiens protein
namespace: protein
def: "A protein that is encoded in the genome of Homo sapiens." [PRO:DAN]
synonym: "human protein" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000036194 ! eukaryotic protein
intersection_of: PR:000000001 ! protein
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036194
name: eukaryotic protein
namespace: protein
def: "A protein that is encoded in the genome of some Eukaryota." [PRO:DAN]
synonym: "Eukaryota protein" EXACT [PRO:DAN]
is_a: PR:000000001 ! protein
intersection_of: PR:000000001 ! protein
intersection_of: only_in_taxon NCBITaxon:2759 ! Eukaryota
relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota

[Term]
id: PR:000045358
name: insulin family protein
namespace: protein
def: "A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide." [PRO:DAN]
comment: Category=family.
synonym: "fam:INS" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000000001 ! protein

[Term]
id: PR:000050567
name: protein-containing material entity
namespace: protein
def: "A material entity that minimally consists of a protein." [PRO:DAN]
comment: Note: This includes single proteins and derivatives thereof (PR:000000001), protein-containing complexes (GO:0032991), and protein aggregates (PR:000050566).
synonym: "protein" NARROW [PRO:DAN]
synonym: "protein aggregate" NARROW [PRO:DAN]
synonym: "protein complex" NARROW [PRO:DAN]
synonym: "protein-containing complex" NARROW [PRO:DAN]
is_a: BFO:0000040 ! material entity
intersection_of: BFO:0000040 ! material entity
intersection_of: has_part PR:000000001 ! protein
relationship: has_part PR:000000001 ! protein

[Term]
id: PR:P01308
name: insulin gene translation product (human)
namespace: protein
def: "An insulin gene translation product that is encoded in the genome of human." [PRO:DAN, UniProtKB:P01308]
comment: Category=organism-gene.
synonym: "hINS" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P01308
is_a: PR:000009054 ! insulin gene translation product
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000009054 ! insulin gene translation product
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P01730
name: T-cell surface glycoprotein CD4 (human)
namespace: protein
def: "A CD4 molecule that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01730]
comment: Category=organism-gene.
synonym: "CD4" RELATED Gene-based [UniProtKB:P01730]
synonym: "hCD4" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface antigen T4/Leu-3 (human)" EXACT [UniProtKB:P01730]
xref: UniProtKB:P01730
is_a: PR:000001004 ! CD4 molecule
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001004 ! CD4 molecule
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P01731
name: T-cell surface glycoprotein CD8 alpha chain (mouse)
namespace: protein
def: "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of mouse." [OMA:P01731, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cd8a" RELATED Gene-based [UniProtKB:P01731]
synonym: "CD8a (mouse)" EXACT [UniProtKB:P01731]
synonym: "Lyt-2" RELATED Gene-based [UniProtKB:P01731]
synonym: "Lyt2" RELATED Gene-based [UniProtKB:P01731]
synonym: "mCD8A" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein Lyt-2 (mouse)" EXACT [UniProtKB:P01731]
xref: UniProtKB:P01731
is_a: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P01732
name: T-cell surface glycoprotein CD8 alpha chain (human)
namespace: protein
def: "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P01732]
comment: Category=organism-gene.
synonym: "CD8A" RELATED Gene-based [UniProtKB:P01732]
synonym: "CD8a (human)" EXACT [UniProtKB:P01732]
synonym: "hCD8A" EXACT PRO-short-label [PRO:DNx]
synonym: "MAL" RELATED Gene-based [UniProtKB:P01732]
synonym: "T-lymphocyte differentiation antigen T8/Leu-2 (human)" EXACT [UniProtKB:P01732]
xref: UniProtKB:P01732
is_a: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P02786
name: transferrin receptor protein 1 (human)
namespace: protein
def: "A transferrin receptor protein 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P02786]
comment: Category=organism-gene.
synonym: "CD71 (human)" EXACT [UniProtKB:P02786]
synonym: "hTFRC" EXACT PRO-short-label [PRO:DNx]
synonym: "p90 (human)" BROAD [UniProtKB:P02786]
synonym: "T9 (human)" EXACT [UniProtKB:P02786]
synonym: "TfR (human)" EXACT [UniProtKB:P02786]
synonym: "TfR1 (human)" EXACT [UniProtKB:P02786]
synonym: "TFRC" RELATED Gene-based [UniProtKB:P02786]
synonym: "TR (human)" BROAD [UniProtKB:P02786]
synonym: "Trfr (human)" EXACT [UniProtKB:P02786]
xref: Reactome:R-HSA-434196 "PR:P02786 located_in GO:0030659"
xref: Reactome:R-HSA-434330 "PR:P02786 located_in GO:0000139"
xref: Reactome:R-HSA-8869124 "PR:P02786 located_in GO:0030665"
xref: Reactome:R-HSA-8961829 "PR:P02786 located_in GO:0010008"
xref: Reactome:R-HSA-917983 "PR:P02786 located_in GO:0005886"
xref: UniProtKB:P02786
is_a: PR:000001945 ! transferrin receptor protein 1
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001945 ! transferrin receptor protein 1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P05555
name: integrin alpha-M (mouse)
namespace: protein
def: "An integrin alpha-M that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P05555]
comment: Category=organism-gene.
synonym: "CD11 antigen-like family member B (mouse)" EXACT [UniProtKB:P05555]
synonym: "CD11b (mouse)" EXACT [UniProtKB:P05555]
synonym: "cell surface glycoprotein MAC-1 subunit alpha (mouse)" EXACT [UniProtKB:P05555]
synonym: "CR-3 alpha chain (mouse)" EXACT [UniProtKB:P05555]
synonym: "Itgam" RELATED Gene-based [UniProtKB:P05555]
synonym: "leukocyte adhesion receptor MO1 (mouse)" EXACT [UniProtKB:P05555]
synonym: "mITGAM" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P05555
is_a: PR:000001012 ! integrin alpha-M
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001012 ! integrin alpha-M
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P06127
name: T-cell surface glycoprotein CD5 (human)
namespace: protein
def: "A T-cell surface glycoprotein CD5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P06127]
comment: Category=organism-gene.
synonym: "CD5" RELATED Gene-based [UniProtKB:P06127]
synonym: "hCD5" EXACT PRO-short-label [PRO:DNx]
synonym: "LEU1" RELATED Gene-based [UniProtKB:P06127]
synonym: "lymphocyte antigen T1/Leu-1 (human)" EXACT [UniProtKB:P06127]
xref: UniProtKB:P06127
is_a: PR:000001839 ! T-cell surface glycoprotein CD5
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001839 ! T-cell surface glycoprotein CD5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06332
name: T-cell surface glycoprotein CD4 (mouse)
namespace: protein
def: "A CD4 molecule that is encoded in the genome of mouse." [OMA:P06332, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cd4" RELATED Gene-based [UniProtKB:P06332]
synonym: "CD4 (mouse)" EXACT [UniProtKB:P06332]
synonym: "mCD4" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell differentiation antigen L3T4 (mouse)" EXACT [UniProtKB:P06332]
synonym: "T-cell surface antigen T4/Leu-3 (mouse)" EXACT [UniProtKB:P06332]
xref: UniProtKB:P06332
is_a: PR:000001004 ! CD4 molecule
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001004 ! CD4 molecule
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P06729
name: T-cell surface antigen CD2 (human)
namespace: protein
def: "A CD2 molecule that is encoded in the genome of human." [PRO:CNA, UniProtKB:P06729]
comment: Category=organism-gene.
synonym: "CD2" RELATED Gene-based [UniProtKB:P06729]
synonym: "erythrocyte receptor (human)" EXACT [UniProtKB:P06729]
synonym: "hCD2" EXACT PRO-short-label [PRO:DNx]
synonym: "LFA-2 (human)" EXACT [UniProtKB:P06729]
synonym: "LFA-3 receptor (human)" EXACT [UniProtKB:P06729]
synonym: "rosette receptor (human)" EXACT [UniProtKB:P06729]
synonym: "SRBC" RELATED Gene-based [UniProtKB:P06729]
synonym: "T-cell surface antigen T11/Leu-5 (human)" EXACT [UniProtKB:P06729]
xref: UniProtKB:P06729
is_a: PR:000001083 ! CD2 molecule
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001083 ! CD2 molecule
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07766
name: T-cell surface glycoprotein CD3 epsilon chain (human)
namespace: protein
def: "A CD3 epsilon that is encoded in the genome of human." [PRO:CNA, UniProtKB:P07766]
comment: Category=organism-gene.
synonym: "CD3E" RELATED Gene-based [UniProtKB:P07766]
synonym: "CD3e (human)" EXACT [UniProtKB:P07766]
synonym: "hCD3E" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface antigen T3/Leu-4 epsilon chain (human)" EXACT [UniProtKB:P07766]
synonym: "T3E" RELATED Gene-based [UniProtKB:P07766]
xref: UniProtKB:P07766
is_a: PR:000001020 ! CD3 epsilon
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001020 ! CD3 epsilon
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P08571
name: monocyte differentiation antigen CD14 (human)
namespace: protein
def: "A CD14 molecule that is encoded in the genome of human." [PRO:WCB, UniProtKB:P08571]
comment: Category=organism-gene.
synonym: "CD14" RELATED Gene-based [UniProtKB:P08571]
synonym: "hCD14" EXACT PRO-short-label [PRO:DNx]
synonym: "myeloid cell-specific leucine-rich glycoprotein (human)" EXACT [UniProtKB:P08571]
xref: UniProtKB:P08571
is_a: PR:000001889 ! CD14 molecule
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001889 ! CD14 molecule
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P08920
name: T-cell surface antigen CD2 (mouse)
namespace: protein
def: "A CD2 molecule that is encoded in the genome of mouse." [OMA:P08920, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cd2" RELATED Gene-based [UniProtKB:P08920]
synonym: "CD2 (mouse)" EXACT [UniProtKB:P08920]
synonym: "LFA-2 (mouse)" EXACT [UniProtKB:P08920]
synonym: "LFA-3 receptor (mouse)" EXACT [UniProtKB:P08920]
synonym: "Ly-37" RELATED Gene-based [UniProtKB:P08920]
synonym: "lymphocyte antigen 37 (mouse)" EXACT [UniProtKB:P08920]
synonym: "mCD2" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface antigen T11/Leu-5 (mouse)" EXACT [UniProtKB:P08920]
xref: UniProtKB:P08920
is_a: PR:000001083 ! CD2 molecule
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001083 ! CD2 molecule
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P10810
name: monocyte differentiation antigen CD14 (mouse)
namespace: protein
def: "A CD14 molecule that is encoded in the genome of mouse." [OMA:P10810, PRO:WCB]
comment: Category=organism-gene.
synonym: "Cd14" RELATED Gene-based [UniProtKB:P10810]
synonym: "CD14 (mouse)" EXACT [UniProtKB:P10810]
synonym: "mCD14" EXACT PRO-short-label [PRO:DNx]
synonym: "myeloid cell-specific leucine-rich glycoprotein (mouse)" EXACT [UniProtKB:P10810]
xref: UniProtKB:P10810
is_a: PR:000001889 ! CD14 molecule
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001889 ! CD14 molecule
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P11215
name: integrin alpha-M (human)
namespace: protein
def: "An integrin alpha-M that is encoded in the genome of human." [PRO:DNx, UniProtKB:P11215]
comment: Category=organism-gene.
synonym: "CD11 antigen-like family member B (human)" EXACT [UniProtKB:P11215]
synonym: "CD11B" RELATED Gene-based [UniProtKB:P11215]
synonym: "cell surface glycoprotein MAC-1 subunit alpha (human)" EXACT [UniProtKB:P11215]
synonym: "CR-3 alpha chain (human)" EXACT [UniProtKB:P11215]
synonym: "CR3A" RELATED Gene-based [UniProtKB:P11215]
synonym: "hITGAM" EXACT PRO-short-label [PRO:DNx]
synonym: "ITGAM" RELATED Gene-based [UniProtKB:P11215]
synonym: "leukocyte adhesion receptor MO1 (human)" EXACT [UniProtKB:P11215]
synonym: "neutrophil adherence receptor (human)" EXACT [UniProtKB:P11215]
xref: UniProtKB:P11215
is_a: PR:000001012 ! integrin alpha-M
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001012 ! integrin alpha-M
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P11836
name: B-lymphocyte antigen CD20 (human)
namespace: protein
def: "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P11836]
comment: Category=organism-gene.
synonym: "B-lymphocyte surface antigen B1 (human)" EXACT [UniProtKB:P11836]
synonym: "Bp35 (human)" EXACT [UniProtKB:P11836]
synonym: "CD20" RELATED Gene-based [UniProtKB:P11836]
synonym: "hMS4A1" EXACT PRO-short-label [PRO:DNx]
synonym: "leukocyte surface antigen Leu-16 (human)" EXACT [UniProtKB:P11836]
synonym: "membrane-spanning 4-domains subfamily A member 1 (human)" EXACT [UniProtKB:P11836]
synonym: "MS4A1" RELATED Gene-based [UniProtKB:P11836]
xref: UniProtKB:P11836
is_a: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P13379
name: T-cell surface glycoprotein CD5 (mouse)
namespace: protein
def: "A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse." [OMA:P13379, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cd5" RELATED Gene-based [UniProtKB:P13379]
synonym: "CD5 (mouse)" EXACT [UniProtKB:P13379]
synonym: "Ly-1" RELATED Gene-based [UniProtKB:P13379]
synonym: "lymphocyte antigen 1 (mouse)" EXACT [UniProtKB:P13379]
synonym: "Lyt-1 (mouse)" EXACT [UniProtKB:P13379]
synonym: "mCD5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P13379
is_a: PR:000001839 ! T-cell surface glycoprotein CD5
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001839 ! T-cell surface glycoprotein CD5
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P13591
name: neural cell adhesion molecule 1 (human)
namespace: protein
def: "A neural cell adhesion molecule 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P13591]
comment: Category=organism-gene.
synonym: "CD56 (human)" EXACT [UniProtKB:P13591]
synonym: "hNCAM1" EXACT PRO-short-label [PRO:DNx]
synonym: "N-CAM-1 (human)" EXACT [UniProtKB:P13591]
synonym: "NCAM" RELATED Gene-based [UniProtKB:P13591]
synonym: "NCAM-1 (human)" EXACT [UniProtKB:P13591]
synonym: "NCAM1" RELATED Gene-based [UniProtKB:P13591]
xref: UniProtKB:P13591
is_a: PR:000001024 ! neural cell adhesion molecule 1
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001024 ! neural cell adhesion molecule 1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P13595
name: neural cell adhesion molecule 1 (mouse)
namespace: protein
def: "A neural cell adhesion molecule 1 that is encoded in the genome of mouse." [OMA:P13595, PRO:DNx]
comment: Category=organism-gene.
synonym: "CD56 (mouse)" EXACT [UniProtKB:P13595]
synonym: "mNCAM1" EXACT PRO-short-label [PRO:DNx]
synonym: "N-CAM-1 (mouse)" EXACT [UniProtKB:P13595]
synonym: "Ncam" RELATED Gene-based [UniProtKB:P13595]
synonym: "NCAM-1 (mouse)" EXACT [UniProtKB:P13595]
synonym: "Ncam1" RELATED Gene-based [UniProtKB:P13595]
xref: UniProtKB:P13595
is_a: PR:000001024 ! neural cell adhesion molecule 1
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001024 ! neural cell adhesion molecule 1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P15391
name: B-lymphocyte antigen CD19 (human)
namespace: protein
def: "A CD19 molecule that is encoded in the genome of human." []
comment: Category=organism-gene.
synonym: "B-lymphocyte surface antigen B4 (human)" EXACT [UniProtKB:P15391]
synonym: "CD19" RELATED Gene-based [UniProtKB:P15391]
synonym: "differentiation antigen CD19 (human)" EXACT [UniProtKB:P15391]
synonym: "hCD19" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface antigen Leu-12 (human)" EXACT [UniProtKB:P15391]
xref: UniProtKB:P15391
is_a: PR:000001002 ! CD19 molecule
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001002 ! CD19 molecule
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16871
name: interleukin-7 receptor subunit alpha (human)
namespace: protein
def: "An interleukin-7 receptor subunit alpha that is encoded in the genome of human." [PRO:WCB, UniProtKB:P16871]
comment: Category=organism-gene.
synonym: "CD127 (human)" EXACT [UniProtKB:P16871]
synonym: "CDw127 (human)" EXACT [UniProtKB:P16871]
synonym: "hIL7R" EXACT PRO-short-label [PRO:DNx]
synonym: "IL-7 receptor subunit alpha (human)" EXACT [UniProtKB:P16871]
synonym: "IL-7R subunit alpha (human)" EXACT [UniProtKB:P16871]
synonym: "IL-7R-alpha (human)" EXACT [UniProtKB:P16871]
synonym: "IL-7RA (human)" EXACT [UniProtKB:P16871]
synonym: "IL7R" RELATED Gene-based [UniProtKB:P16871]
xref: UniProtKB:P16871
is_a: PR:000001869 ! interleukin-7 receptor subunit alpha
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001869 ! interleukin-7 receptor subunit alpha
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16872
name: interleukin-7 receptor subunit alpha (mouse)
namespace: protein
def: "An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse." [OMA:P16872, PRO:DNx]
comment: Category=organism-gene.
synonym: "CD127 (mouse)" EXACT [UniProtKB:P16872]
synonym: "IL-7 receptor subunit alpha (mouse)" EXACT [UniProtKB:P16872]
synonym: "IL-7R subunit alpha (mouse)" EXACT [UniProtKB:P16872]
synonym: "IL-7R-alpha (mouse)" EXACT [UniProtKB:P16872]
synonym: "IL-7RA (mouse)" EXACT [UniProtKB:P16872]
synonym: "Il7r" RELATED Gene-based [UniProtKB:P16872]
synonym: "mIL7R" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16872
is_a: PR:000001869 ! interleukin-7 receptor subunit alpha
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001869 ! interleukin-7 receptor subunit alpha
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P17542
name: T-cell acute lymphocytic leukemia protein 1 (human)
namespace: protein
def: "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P17542]
comment: Category=organism-gene.
synonym: "BHLHA17" RELATED Gene-based [UniProtKB:P17542]
synonym: "class A basic helix-loop-helix protein 17 (human)" EXACT [UniProtKB:P17542]
synonym: "hTAL1" EXACT PRO-short-label [PRO:DNx]
synonym: "SCL" RELATED Gene-based [UniProtKB:P17542]
synonym: "Stem cell protein (human)" EXACT [UniProtKB:P17542]
synonym: "T-cell leukemia/lymphoma protein 5 (human)" EXACT [UniProtKB:P17542]
synonym: "TAL-1 (human)" EXACT [UniProtKB:P17542]
synonym: "TAL1" RELATED Gene-based [UniProtKB:P17542]
synonym: "TCL5" RELATED Gene-based [UniProtKB:P17542]
xref: Reactome:R-HSA-8956511 "PR:P17542 located_in GO:0005654"
xref: UniProtKB:P17542
is_a: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P19437
name: B-lymphocyte antigen CD20 (mouse)
namespace: protein
def: "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse." [OMA:P19437, PRO:DNx]
comment: Category=organism-gene.
synonym: "B-cell differentiation antigen Ly-44 (mouse)" EXACT [UniProtKB:P19437]
synonym: "Cd20" RELATED Gene-based [UniProtKB:P19437]
synonym: "CD20 (mouse)" EXACT [UniProtKB:P19437]
synonym: "Ly-44" RELATED Gene-based [UniProtKB:P19437]
synonym: "lymphocyte antigen 44 (mouse)" EXACT [UniProtKB:P19437]
synonym: "membrane-spanning 4-domains subfamily A member 1 (mouse)" EXACT [UniProtKB:P19437]
synonym: "mMS4A1" EXACT PRO-short-label [PRO:DNx]
synonym: "Ms4a1" RELATED Gene-based [UniProtKB:P19437]
synonym: "Ms4a2" RELATED Gene-based [UniProtKB:P19437]
xref: UniProtKB:P19437
is_a: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P22091
name: T-cell acute lymphocytic leukemia protein 1 homolog (mouse)
namespace: protein
def: "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse." [OMA:P22091, PRO:DNx]
comment: Category=organism-gene.
synonym: "mTAL1" EXACT PRO-short-label [PRO:DNx]
synonym: "Scl" RELATED Gene-based [UniProtKB:P22091]
synonym: "Stem cell protein (mouse)" EXACT [UniProtKB:P22091]
synonym: "Tal-1" RELATED Gene-based [UniProtKB:P22091]
synonym: "TAL-1 (mouse)" EXACT [UniProtKB:P22091]
synonym: "Tal1" RELATED Gene-based [UniProtKB:P22091]
xref: UniProtKB:P22091
is_a: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P22646
name: T-cell surface glycoprotein CD3 epsilon chain (mouse)
namespace: protein
def: "A CD3 epsilon that is encoded in the genome of mouse." [OMA:P22646, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cd3e" RELATED Gene-based [UniProtKB:P22646]
synonym: "CD3e (mouse)" EXACT [UniProtKB:P22646]
synonym: "mCD3E" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface antigen T3/Leu-4 epsilon chain (mouse)" EXACT [UniProtKB:P22646]
xref: UniProtKB:P22646
is_a: PR:000001020 ! CD3 epsilon
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001020 ! CD3 epsilon
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P25918
name: B-lymphocyte antigen CD19 (mouse)
namespace: protein
def: "A CD19 molecule that is encoded in the genome of mouse." [OMA:P25918, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cd19" RELATED Gene-based [UniProtKB:P25918]
synonym: "CD19 (mouse)" EXACT [UniProtKB:P25918]
synonym: "differentiation antigen CD19 (mouse)" EXACT [UniProtKB:P25918]
synonym: "mCD19" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P25918
is_a: PR:000001002 ! CD19 molecule
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001002 ! CD19 molecule
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P28906
name: hematopoietic progenitor cell antigen CD34 (human)
namespace: protein
def: "A CD34 molecule that is encoded in the genome of human." []
comment: Category=organism-gene.
synonym: "CD34" RELATED Gene-based [UniProtKB:P28906]
synonym: "hCD34" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28906
is_a: PR:000001003 ! CD34 molecule
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001003 ! CD34 molecule
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P33151
name: cadherin-5 (human)
namespace: protein
def: "A cadherin-5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P33151]
comment: Category=organism-gene.
synonym: "7B4 antigen (human)" EXACT [UniProtKB:P33151]
synonym: "CD144 (human)" EXACT [UniProtKB:P33151]
synonym: "CDH5" RELATED Gene-based [UniProtKB:P33151]
synonym: "hCDH5" EXACT PRO-short-label [PRO:DNx]
synonym: "vascular endothelial cadherin (human)" EXACT [UniProtKB:P33151]
synonym: "VE-cadherin (human)" EXACT [UniProtKB:P33151]
xref: UniProtKB:P33151
is_a: PR:000001444 ! cadherin-5
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000001444 ! cadherin-5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P35461
name: lymphocyte antigen 6G (mouse)
namespace: protein
def: "A lymphocyte antigen 6G that is encoded in the genome of mouse." [PRO:CNA, UniProtKB:P35461]
comment: Category=organism-gene.
synonym: "Ly-6G (mouse)" EXACT [UniProtKB:P35461]
synonym: "Ly-6G.1 (mouse)" EXACT [UniProtKB:P35461]
synonym: "Ly6g" RELATED Gene-based [UniProtKB:P35461]
synonym: "mLy6g" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35461
is_a: PR:000002978 ! lymphocyte antigen 6G
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000002978 ! lymphocyte antigen 6G
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P35918
name: vascular endothelial growth factor receptor 2 (mouse)
namespace: protein
def: "A vascular endothelial growth factor receptor 2 that is encoded in the genome of mouse." [OMA:P35918, PRO:DNx]
comment: Category=organism-gene.
synonym: "CD309 (mouse)" EXACT [UniProtKB:P35918]
synonym: "fetal liver kinase 1 (mouse)" EXACT [UniProtKB:P35918]
synonym: "Flk-1" RELATED Gene-based [UniProtKB:P35918]
synonym: "FLK-1 (mouse)" EXACT [UniProtKB:P35918]
synonym: "Flk1" RELATED Gene-based [UniProtKB:P35918]
synonym: "Kdr" RELATED Gene-based [UniProtKB:P35918]
synonym: "kinase NYK (mouse)" EXACT [UniProtKB:P35918]
synonym: "mKDR" EXACT PRO-short-label [PRO:DNx]
synonym: "protein-tyrosine kinase receptor flk-1 (mouse)" EXACT [UniProtKB:P35918]
synonym: "VEGFR-2 (mouse)" EXACT [UniProtKB:P35918]
xref: UniProtKB:P35918
is_a: PR:000002112 ! vascular endothelial growth factor receptor 2
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000002112 ! vascular endothelial growth factor receptor 2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P35968
name: vascular endothelial growth factor receptor 2 (human)
namespace: protein
def: "A vascular endothelial growth factor receptor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P35968]
comment: Category=organism-gene.
synonym: "CD309 (human)" EXACT [UniProtKB:P35968]
synonym: "fetal liver kinase 1 (human)" EXACT [UniProtKB:P35968]
synonym: "FLK-1 (human)" EXACT [UniProtKB:P35968]
synonym: "FLK1" RELATED Gene-based [UniProtKB:P35968]
synonym: "hKDR" EXACT PRO-short-label [PRO:DNx]
synonym: "KDR" RELATED Gene-based [UniProtKB:P35968]
synonym: "kinase insert domain receptor (human)" EXACT [UniProtKB:P35968]
synonym: "protein-tyrosine kinase receptor flk-1 (human)" EXACT [UniProtKB:P35968]
synonym: "VEGFR-2 (human)" EXACT [UniProtKB:P35968]
synonym: "VEGFR2" RELATED Gene-based [UniProtKB:P35968]
xref: DTO:03100560
xref: UniProtKB:P35968
is_a: PR:000002112 ! vascular endothelial growth factor receptor 2
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000002112 ! vascular endothelial growth factor receptor 2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P37237
name: fibroblast growth factor 8 (mouse)
namespace: protein
def: "A fibroblast growth factor 8 that is encoded in the genome of mouse." [OMA:P37237, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aigf" RELATED Gene-based [UniProtKB:P37237]
synonym: "AIGF (mouse)" EXACT [UniProtKB:P37237]
synonym: "androgen-induced growth factor (mouse)" EXACT [UniProtKB:P37237]
synonym: "FGF-8 (mouse)" EXACT [UniProtKB:P37237]
synonym: "Fgf8" RELATED Gene-based [UniProtKB:P37237]
synonym: "HBGF-8 (mouse)" RELATED [UniProtKB:P37237]
synonym: "heparin-binding growth factor 8 (mouse)" RELATED [UniProtKB:P37237]
synonym: "mFGF8" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P37237
is_a: PR:000007499 ! fibroblast growth factor 8
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000007499 ! fibroblast growth factor 8
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P55075
name: fibroblast growth factor 8 (human)
namespace: protein
def: "A fibroblast growth factor 8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P55075]
comment: Category=organism-gene.
synonym: "AIGF" RELATED Gene-based [UniProtKB:P55075]
synonym: "androgen-induced growth factor (human)" EXACT [UniProtKB:P55075]
synonym: "FGF-8 (human)" EXACT [UniProtKB:P55075]
synonym: "FGF8" RELATED Gene-based [UniProtKB:P55075]
synonym: "HBGF-8 (human)" BROAD [UniProtKB:P55075]
synonym: "heparin-binding growth factor 8 (human)" BROAD [UniProtKB:P55075]
synonym: "hFGF8" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P55075
is_a: PR:000007499 ! fibroblast growth factor 8
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000007499 ! fibroblast growth factor 8
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P55284
name: cadherin-5 (mouse)
namespace: protein
def: "A cadherin-5 that is encoded in the genome of mouse." [OMA:P55284, PRO:DNx]
comment: Category=organism-gene.
synonym: "CD144 (mouse)" EXACT [UniProtKB:P55284]
synonym: "Cdh5" RELATED Gene-based [UniProtKB:P55284]
synonym: "mCDH5" EXACT PRO-short-label [PRO:DNx]
synonym: "vascular endothelial cadherin (mouse)" EXACT [UniProtKB:P55284]
synonym: "VE-cadherin (mouse)" EXACT [UniProtKB:P55284]
xref: UniProtKB:P55284
is_a: PR:000001444 ! cadherin-5
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001444 ! cadherin-5
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q15465
name: sonic hedgehog protein (human)
namespace: protein
def: "A sonic hedgehog protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15465]
comment: Category=organism-gene.
synonym: "HHG-1 (human)" EXACT [UniProtKB:Q15465]
synonym: "hSHH" EXACT PRO-short-label [PRO:DNx]
synonym: "SHH" RELATED Gene-based [UniProtKB:Q15465]
synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (human)" EXACT [UniProtKB:Q15465]
synonym: "ShhNC (human)" EXACT [UniProtKB:Q15465]
xref: UniProtKB:Q15465
is_a: PR:000014841 ! sonic hedgehog protein
is_a: PR:000029067 ! Homo sapiens protein
intersection_of: PR:000014841 ! sonic hedgehog protein
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q62226
name: sonic hedgehog protein (mouse)
namespace: protein
def: "A sonic hedgehog protein that is encoded in the genome of mouse." [OMA:Q62226, PRO:DNx]
comment: Category=organism-gene.
synonym: "HHG-1 (mouse)" EXACT [UniProtKB:Q62226]
synonym: "Hhg1" RELATED Gene-based [UniProtKB:Q62226]
synonym: "mSHH" EXACT PRO-short-label [PRO:DNx]
synonym: "Shh" RELATED Gene-based [UniProtKB:Q62226]
synonym: "SHH (mouse)" EXACT [UniProtKB:Q62226]
synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (mouse)" EXACT [UniProtKB:Q62226]
synonym: "ShhNC (mouse)" EXACT [UniProtKB:Q62226]
xref: UniProtKB:Q62226
is_a: PR:000014841 ! sonic hedgehog protein
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000014841 ! sonic hedgehog protein
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q62351
name: transferrin receptor protein 1 (mouse)
namespace: protein
def: "A transferrin receptor protein 1 that is encoded in the genome of mouse." [OMA:Q62351, PRO:DNx]
comment: Category=organism-gene.
synonym: "CD71 (mouse)" EXACT [UniProtKB:Q62351]
synonym: "mTFRC" EXACT PRO-short-label [PRO:DNx]
synonym: "TfR (mouse)" EXACT [UniProtKB:Q62351]
synonym: "TfR1 (mouse)" EXACT [UniProtKB:Q62351]
synonym: "Tfrc" RELATED Gene-based [UniProtKB:Q62351]
synonym: "TR (mouse)" RELATED [UniProtKB:Q62351]
synonym: "Trfr" RELATED Gene-based [UniProtKB:Q62351]
xref: UniProtKB:Q62351
is_a: PR:000001945 ! transferrin receptor protein 1
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001945 ! transferrin receptor protein 1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q64314
name: hematopoietic progenitor cell antigen CD34 (mouse)
namespace: protein
def: "A CD34 molecule that is encoded in the genome of mouse." [OMA:Q64314, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cd34" RELATED Gene-based [UniProtKB:Q64314]
synonym: "CD34 (mouse)" EXACT [UniProtKB:Q64314]
synonym: "mCD34" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q64314
is_a: PR:000001003 ! CD34 molecule
is_a: PR:000029032 ! Mus musculus protein
intersection_of: PR:000001003 ! CD34 molecule
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9V7U0
name: pro-resilin (fruit fly)
namespace: protein
def: "A protein that is a translation product of the resilin gene in fruit fly." [PRO:DNx, UniProtKB:Q9V7U0]
comment: Category=organism-gene.
synonym: "CG15920" RELATED Gene-based [UniProtKB:Q9V7U0]
synonym: "fly-resilin" EXACT PRO-short-label [PRO:DNx]
synonym: "resilin" RELATED Gene-based [UniProtKB:Q9V7U0]
xref: UniProtKB:Q9V7U0
is_a: PR:000029060 ! Drosophila melanogaster protein
intersection_of: PR:000000001 ! protein
intersection_of: has_gene_template http://flybase.org/reports/FBgn0034157 ! resilin (fruit fly)
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
relationship: has_gene_template http://flybase.org/reports/FBgn0034157 ! resilin (fruit fly)

[Term]
id: RO:0002577
name: system
def: "A material entity consisting of multiple components that are causally integrated." []
is_a: BFO:0000040 ! material entity
property_value: editor_note "May be replaced by a BFO class, as discussed in http://www.jbiomedsem.com/content/4/1/43" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "http://www.jbiomedsem.com/content/4/1/43" xsd:string

[Term]
id: SO:0000010
name: protein_coding
namespace: sequence
comment: Category=external.
synonym: "protein-coding" EXACT []
is_a: BFO:0000019 ! quality

[Term]
id: SO:0000110
name: sequence_feature
namespace: sequence
def: "An extent of biological sequence." [SO:ke]
synonym: "located sequence feature" RELATED []
synonym: "located_sequence_feature" EXACT []
synonym: "sequence feature" EXACT []

[Term]
id: SO:0000704
name: gene
namespace: sequence
def: "A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions." [SO:immuno_workshop]
is_a: SO:0000110 ! sequence_feature

[Term]
id: SO:0001217
name: protein_coding_gene
namespace: sequence
synonym: "protein coding gene" EXACT []
is_a: SO:0000704 ! gene
relationship: has_quality SO:0000010 ! protein_coding

[Term]
id: UBERON:0000000
name: processual entity
namespace: uberon
def: "An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity." [span:ProcessualEntity]
subset: common_anatomy
subset: upper_level
xref: BFO:0000003
is_a: BFO:0000003 ! occurrent
disjoint_from: UBERON:0001062 ! anatomical entity
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000005
name: chemosensory organ
namespace: uberon
subset: functional_classification
subset: uberon_slim
synonym: "chemosensory sensory organ" EXACT [FBbt:00005157]
xref: FBbt:00005157 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0000020 ! sense organ
intersection_of: UBERON:0000020 ! sense organ
intersection_of: capable_of GO:0007606 ! sensory perception of chemical stimulus
relationship: capable_of GO:0007606 ! sensory perception of chemical stimulus
relationship: part_of UBERON:0001016 ! nervous system
relationship: part_of UBERON:0005726 ! chemosensory system

[Term]
id: UBERON:0000006
name: islet of Langerhans
namespace: uberon
def: "The clusters of hormone-producing cells that are scattered throughout the pancreas." [MA:0000127, MESH:A03.734.414, MP:0005215]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "island of Langerhans" RELATED [BTO:0000991]
synonym: "island of pancreas" RELATED [BTO:0000991]
synonym: "islets of Langerhans" RELATED []
synonym: "pancreatic insula" EXACT []
synonym: "pancreatic islet" EXACT []
xref: AAO:0010406
xref: BTO:0000991
xref: CALOHA:TS-0741
xref: EFO:0000856
xref: EMAPA:32927
xref: EV:0100130
xref: FMA:16016
xref: GAID:324
xref: MA:0000127
xref: MAT:0000076
xref: MESH:D007515
xref: MIAA:0000076
xref: NCIT:C12608
xref: UMLS:C0022131 {source="ncithesaurus:Islet_of_Langerhans"}
xref: VHOG:0000646
xref: Wikipedia:Islets_of_Langerhans
xref: XAO:0000159
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0034922 ! cell cluster
relationship: contributes_to_morphology_of UBERON:0000016 ! endocrine pancreas
relationship: has_part CL:0000168 {source="PMID:16417468"} ! insulin secreting cell
relationship: has_part CL:0000172 {source="PMID:16417468"} ! somatostatin secreting cell
relationship: has_part CL:0000696 {gci_filler="NCBITaxon:117570", gci_relation="part_of", source="PMID:16417468"} ! PP cell
relationship: has_part CL:0002067 {source="PMID:16417468"} ! type A enteroendocrine cell
relationship: part_of UBERON:0000016 ! endocrine pancreas
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anatomical structure which consists of glands developed from pancreatic ducts in the larvae and secrete insulin.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010406", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "Mammals, birds, reptiles and amphibians have a pancreas with similar histology and mode of development, while in some fish, the islet cells are segregated as Brockmann bodies.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000646", ontology="VHOG", source="PMID:7600975 Slack JMW, Developmental biology of the pancreas. Development (1995)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "A primitive exocrine pancreas can be found in holocephalan cartilaginous fish; a pancreatic duct directly ending in the gut lumen is connected to a glandular structure made of exocrine cells and associated with cell islets, which comprises three different hormone-producing cell types: insulin, somatostatin and glucagon (Yui and Fujita, 1986)" xsd:string {source="PMID:16417468"}
property_value: UBPROP:0000202 FMA:76489

[Term]
id: UBERON:0000009
name: submucosa
namespace: uberon
def: "A layer of dense irregular connective tissue that lines organs and supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle. [WP,unvetted]." [Wikipedia:Submucosa]
subset: pheno_slim
subset: uberon_slim
synonym: "organ submucosa" EXACT [FMA:85391]
synonym: "region of submucosa" EXACT [FMA:85392]
synonym: "submucosa of organ" EXACT [FMA:85391]
synonym: "submucosa of region of organ" EXACT [FMA:85392]
synonym: "submucous layer" RELATED [BTO:0002107]
synonym: "tela submucosa" RELATED [BTO:0002107]
synonym: "tunica submucosa" RELATED []
xref: BTO:0002107
xref: FMA:85391
xref: FMA:85392
xref: NCIT:C13167
xref: SCTID:68439008
xref: UMLS:C0225344 {source="ncithesaurus:Submucosa"}
xref: Wikipedia:Submucosa
is_a: UBERON:0004923 ! organ component layer
relationship: composed_primarily_of UBERON:0002384 ! connective tissue
relationship: immediately_deep_to UBERON:0000344 ! mucosa
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI
property_value: UBPROP:0000007 "submucosal" xsd:string

[Term]
id: UBERON:0000010
name: peripheral nervous system
namespace: uberon
def: "A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GO:0007422]
subset: cumbo
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "pars peripherica" EXACT OMO:0003011 [FMA:9903, FMA:TA, Wikipedia:Peripheral_nervous_system]
synonym: "PNS" BROAD OMO:0003000 []
synonym: "systema nervosum periphericum" EXACT OMO:0003011 [FMA:9903, FMA:TA, Wikipedia:Peripheral_nervous_system]
xref: AAO:0000429
xref: BAMS:PNS
xref: BILA:0000081
xref: BIRNLEX:1111
xref: BTO:0001028
xref: CALOHA:TS-0808
xref: EFO:0000891
xref: EHDAA2:0001445
xref: EHDAA:2893
xref: EMAPA:16665
xref: EV:0100335
xref: FBbt:00005098 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:9903
xref: GAID:715
xref: MA:0000218
xref: MAT:0000338
xref: MESH:D017933
xref: MIAA:0000338
xref: NCIT:C12465
xref: neuronames:3232
xref: SCTID:362292005
xref: TAO:0000142
xref: UMLS:C0206417 {source="ncithesaurus:Peripheral_Nervous_System", source="BIRNLEX:1111"}
xref: UMLS:C1305921 {source="BIRNLEX:1111"}
xref: VHOG:0000399
xref: Wikipedia:Peripheral_nervous_system
xref: XAO:0000178
xref: ZFA:0000142
is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision
relationship: part_of UBERON:0001016 ! nervous system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Nervous structures including ganglia outside of the central nervous system. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000142", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Part of nervous system in which nerves extend throughout the body outside of the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000429", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The peripheral nervous system (PNS) is the part of the nervous system connected to the CNS which contains cranial nerves III - XII, spinal, peripheral and autonomic nerves. (CUMBO)" xsd:string {source="http://neurolex.org/wiki/Cumbo_terms"}
property_value: UBPROP:0000003 "(...) specific vertebrate traits within the chordate phylum such as skeletal tissues, PNS, and spectacular head and brain development, are linked to the NC (neural crest) and its derivatives.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000399", ontology="VHOG", source="DOI:10.1007/978-0-387-46954-6_6 Dupin E, Creuzet S, Le Douarin NM, The contribution of the neural crest to the vertebrate body. Advances in experimental medicine and biology (2006)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000013
name: sympathetic nervous system
namespace: uberon
def: "The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]." [GO:0048485]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "pars sympathica divisionis autonomici systematis nervosi" EXACT OMO:0003011 [FMA:9906, FMA:TA]
synonym: "pars sympathica divisionis autonomici systematis nervosi" RELATED OMO:0003011 [Wikipedia:Sympathetic_nervous_system]
synonym: "sympathetic nervous system" EXACT []
synonym: "sympathetic part of autonomic division of nervous system" EXACT []
xref: AAO:0010487
xref: BIRNLEX:2516
xref: BTO:0001832
xref: CALOHA:TS-2050
xref: EFO:0000893
xref: EHDAA2:0001971
xref: EHDAA:3769
xref: EMAPA:16985
xref: FMA:9906
xref: GAID:710
xref: MA:0000225
xref: MESH:D013564
xref: MIAA:0000100
xref: NCIT:C12795
xref: SCTID:362484004
xref: TAO:0001576
xref: UMLS:C0039044 {source="BIRNLEX:2516", source="ncithesaurus:Sympathetic_Nervous_System"}
xref: UMLS:C1269646 {source="BIRNLEX:2516"}
xref: VHOG:0000384
xref: Wikipedia:Sympathetic_nervous_system
xref: ZFA:0001576
is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision
relationship: contributes_to_morphology_of UBERON:0002410 ! autonomic nervous system
relationship: part_of UBERON:0002410 {source="FMA", source="MA", source="ZFA-modified-from-isa"} ! autonomic nervous system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/77/Gray838.png" xsd:anyURI
property_value: UBPROP:0000001 "Part of the autonomic nervous system which has opposing physiological effects of the parasympathetic nervous system. Examples include increasing the heart rate or constricting the blood vessels.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010487", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The part of the autonomic nervous system which chiefly contains adrenergic fibres and tends to control and reduce secretions, decrease the contractility and hence the tone of smooth muscles and provoke the contraction of blood vessels. Essentially, it consists of preganglionic fibres from the thoracic and upper lumbar parts of the spinal cord. These fibres, by means of delicate rami communicantes, cross over to ganglia sited in a pair of ganglionated cords on each side of the vertebral column or to more peripheral ganglia. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000384", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "The autonomic nervous system is composed of three divisions: the sympathetic division, the parasympathetic division, and the enteric division. (...) In ray-finned teleost fishes, a sympathetic chain is present, and dual innervation of additional organs can be observed. A similar pattern can be found in amphibians (...). The evolution of the autonomic nervous system has been quite conservative, especially in the tetrapod lineage.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000384", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.461-463", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "has developmental contribution from NC in verteberates (https://github.com/obophenotype/uberon/wiki/The-neural-crest)" xsd:string

[Term]
id: UBERON:0000014
name: zone of skin
namespace: uberon
def: "Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Skin]
subset: pheno_slim
synonym: "portion of skin" EXACT []
synonym: "region of skin" EXACT []
synonym: "skin" EXACT [MA:0000151]
synonym: "skin region" EXACT []
synonym: "skin zone" EXACT []
xref: EHDAA2:0001844
xref: EHDAA:6530
xref: EMAPA:17525
xref: EV:0100152
xref: FMA:86166
xref: GAID:933
xref: MA:0000151
xref: MAT:0000284
xref: MESH:D012867
xref: MIAA:0000284
xref: SCTID:20795001
xref: VHOG:0000860
xref: Wikipedia:Skin
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0034944 {source="FMA"} ! zone of organ
relationship: has_part UBERON:0001003 ! skin epidermis
relationship: has_part UBERON:0002067 ! dermis
relationship: part_of UBERON:0002097 ! skin of body
property_value: curator_notes "Note the distinction between the entire skin of the body, of which there is only 1 in an organism, and zones of skin, of which there can be many. Examples: skin of knee" xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e8/HumanSkinDiagram.jpg" xsd:anyURI
property_value: UBPROP:0000003 "(...) it is well-established that neural crest cells contribute to both the dermal skeleton (craniofacial bone, teeth, and the caudal fin rays of teleosts) and the integument, including craniofacial dermis and all pigment cells outside the retina (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000860", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2008.01043.x Vickaryous MK, Sire JY, The integumentary skeleton of tetrapods: origin, evolution, and development. J Anat (2009)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "we assume that mouse, HOG and GAID all mean zone of skin when they say skin. We also choose skin as an exact synonym, as it is more intuitive" xsd:string

[Term]
id: UBERON:0000015
name: non-material anatomical boundary
namespace: uberon
def: "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." [CARO:0000010]
comment: Except in the case of abstracted fiat boundaries such as the midline plane of an organism, all 2D anatomical entities have a 3 dimensional projection. For example, the surface of the shell of a muscle has a distinct shape that projects into the third dimension. Note that boundaries are 2D structures. They have no thickness - and so can not be sites of gene expression or gene product localisation. For this, use boundary region terms.
subset: common_anatomy
subset: upper_level
synonym: "anatomical boundary" EXACT [CARO:0000010]
xref: AEO:0000192
xref: CARO:0000010
xref: FMA:50705
is_a: UBERON:0000466 {source="CARO"} ! immaterial anatomical entity
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000016
name: endocrine pancreas
namespace: uberon
def: "The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin." [GO:GO, http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: human_reference_atlas
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "endocrine pancreas" EXACT []
synonym: "endocrine part of pancreas" RELATED [BTO:0000650]
synonym: "islets of Langerhans part of pancreas" RELATED []
synonym: "pars endocrina pancreatis" EXACT []
xref: BTO:0000650
xref: CALOHA:TS-1302
xref: EFO:0002542
xref: EMAPA:35305
xref: EV:0100129
xref: FMA:16018
xref: MA:0001582
xref: MESH:D007515 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: NCIT:C32509
xref: SCTID:361339003
xref: TAO:0001260
xref: VHOG:0000049
xref: Wikipedia:Islets_of_Langerhans
xref: ZFA:0001260
is_a: UBERON:0000471 {source="ZFA"} ! compound organ component
is_a: UBERON:0004119 ! endoderm-derived structure
relationship: capable_of GO:0030073 {source="GO"} ! insulin secretion
relationship: capable_of GO:0070091 {source="GO"} ! glucagon secretion
relationship: capable_of GO:0070253 {source="GO"} ! somatostatin secretion
relationship: composed_primarily_of UBERON:0000006 ! islet of Langerhans
relationship: contributes_to_morphology_of UBERON:0001264 ! pancreas
relationship: develops_from UBERON:0003923 ! dorsal pancreatic bud
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000949 {source="AAO", source="FMA", source="XAO"} ! endocrine system
relationship: part_of UBERON:0001264 ! pancreas
property_value: editor_note "create a separate class for distributed pancreas, eg cyclostomes?" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The part of the pancreas that acts as an endocrine gland, consisting of the islets of Langerhans, which secrete insulin and other hormones. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000049", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/Pancreas"}
property_value: UBPROP:0000001 "The zebrafish endocrine pancreas is composed of small groups of islet cells that are distributed throughout the exocrine pancreas. The islet cells produce insulin, glucagon and somatostatin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001260", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000049", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "endocrine and exocrine pancreas are not co-associated in hagfishes or lampreys" xsd:string {source="PMID:20959416"}

[Term]
id: UBERON:0000017
name: exocrine pancreas
namespace: uberon
def: "The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]." [GOC:GO, http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "exocrine component of pancreas" RELATED []
synonym: "exocrine pancreas" EXACT []
synonym: "exocrine part of pancreas" RELATED [BTO:0000434]
synonym: "pars exocrina pancreatis" EXACT []
xref: AAO:0010407
xref: BTO:0000434
xref: CALOHA:TS-1241
xref: EMAPA:35328
xref: EV:0100093
xref: FMA:16017
xref: MA:0002415
xref: MESH:D046790 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C32546
xref: SCTID:248202004
xref: TAO:0001249
xref: UMLS:C0553695 {source="ncithesaurus:Exocrine_Pancreas"}
xref: VHOG:0000048
xref: Wikipedia:Exocrine_component_of_pancreas
xref: XAO:0000137
xref: ZFA:0001249
is_a: UBERON:0000409 ! serous gland
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0005177 ! trunk region element
relationship: capable_of_part_of GO:0007586 ! digestion
relationship: contributes_to_morphology_of UBERON:0001264 ! pancreas
relationship: develops_from UBERON:0003924 ! ventral pancreatic bud
relationship: has_part UBERON:0001263 ! pancreatic acinus
relationship: has_part UBERON:0007329 ! pancreatic duct
relationship: part_of UBERON:0001264 ! pancreas
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The exocrine pancreas is composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001249", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The part of the pancreas that acts as an exocrine gland, consisting of the pancreatic acini, which produce pancreatic juice and secrete it into the intestine to aid in protein digestion. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000048", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/Pancreas"}
property_value: UBPROP:0000003 "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000048", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000018
name: compound eye
namespace: uberon
def: "A light sensing organ composed of ommatidia." [FB:gg, Wikipedia:Compound_eye]
subset: organ_slim
subset: uberon_slim
synonym: "adult compound eye" RELATED []
synonym: "faceted eye" RELATED []
synonym: "Facettenauge" RELATED [BTO:0001921]
synonym: "insect eye" RELATED []
synonym: "Komplexauge" RELATED [BTO:0001921]
synonym: "zusammengesetztes Auge" RELATED [BTO:0001921]
xref: BTO:0001921
xref: FBbt:00004508 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: HAO:0000217
xref: IDOMAL:0002421 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: TGMA:0000024
xref: Wikipedia:Compound_eye
is_a: UBERON:0015165 ! multi-unit eye
intersection_of: UBERON:0000970 ! eye
intersection_of: composed_primarily_of UBERON:0000971 ! ommatidium
relationship: composed_primarily_of UBERON:0000971 ! ommatidium
relationship: only_in_taxon NCBITaxon:6656 {source="PMID:21062451"} ! Arthropoda
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/457" xsd:anyURI
property_value: UBPROP:0000008 "The term compound eye is sometimes used for the multi-unit eyes of annelids, bivalves, echinoderms. We follow Richter et al and restrict this class to the arthropod structure for these structures" xsd:string {source="PMID:21062451"}

[Term]
id: UBERON:0000019
name: camera-type eye
namespace: uberon
def: "An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid." [GO:0043010, https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "camera-type eye plus associated structures" RELATED []
synonym: "eye" BROAD [FMA:54448]
synonym: "eyes" RELATED OMO:0003004 [TAO:0000107]
synonym: "orbital part of face" RELATED [FMA:54448]
synonym: "orbital region" RELATED [FMA:54448]
synonym: "regio orbitalis" EXACT OMO:0003011 [FMA:54448, FMA:TA]
synonym: "vertebrate eye" NARROW []
xref: AAO:0010340
xref: BIRNLEX:1169
xref: BTO:0004688
xref: EHDAA2:0000484
xref: EHDAA:936
xref: EMAPA:16198
xref: FMA:54448
xref: MA:0000261
xref: NCIT:C12401
xref: SCTID:181143004
xref: TAO:0000107
xref: UMLS:C0015392 {source="BIRNLEX:1169", source="ncithesaurus:Eye"}
xref: UMLS:C1280202 {source="BIRNLEX:1169"}
xref: VHOG:0000275
xref: XAO:0000179
xref: ZFA:0000107
is_a: UBERON:0000047 ! simple eye
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
is_a: UBERON:0015212 ! lateral structure
relationship: develops_from UBERON:0003072 {evidence="definitional"} ! optic cup
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: has_part UBERON:0000965 ! lens of camera-type eye
relationship: has_part UBERON:0000966 ! retina
relationship: in_lateral_side_of UBERON:0000033 ! head
relationship: part_of UBERON:0004088 ! orbital region
property_value: UBPROP:0000001 "A cavitated compound organ that transduces light waves into neural signals.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000107", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000275", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "FMA distinguishes Eye (subdivision of face) which has its parts an Eyeball (organ), as well as other structures, and the orbit of skull. MA includes eyelid, conjunctiva and lacrimal apparatus as part of MA:eye - consistent with FMA - so we can infer that MA:eye is more like FMA:eye than FMA:eyeball. For other AOs this distinction is less meaningful - e.g. ZFA has no eyelid; XAO has no eyelid, but it has conjuctiva, which is considered part of the xao:eye. GO considers eyelid development part of eye development. See also notes on optic nerve - XAO, AAO and BTO consider this part of the eye. MA considers the eye muscles part of the eye, whereas FMA has a class 'orbital content' for this" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0000020
name: sense organ
namespace: uberon
def: "An organ that is capable of transducing sensory stimulus to the nervous system." [https://github.com/obophenotype/uberon/issues/549, https://orcid.org/0000-0002-6601-2165]
subset: uberon_slim
synonym: "organ of sense organ system" EXACT [OBOL:accepted]
synonym: "organ of sensory organ system" EXACT [OBOL:accepted]
synonym: "organ of sensory system" EXACT [OBOL:accepted]
synonym: "sense organ system organ" EXACT [OBOL:automatic]
synonym: "sensillum" NARROW [WBbt:0006929]
synonym: "sensor" RELATED []
synonym: "sensory organ" EXACT []
synonym: "sensory organ system organ" EXACT [OBOL:automatic]
synonym: "sensory system organ" EXACT [OBOL:accepted]
synonym: "Sinnesorgan" RELATED [BTO:0000202]
xref: AEO:0000094
xref: BSA:0000121
xref: BTO:0000202
xref: CALOHA:TS-2043
xref: EHDAA2:0001824
xref: EHDAA:500
xref: EMAPA:35955
xref: FBbt:00005155 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: GAID:63
xref: HAO:0000930
xref: MA:0000017
xref: MESH:D012679
xref: NCIT:C33224
xref: SCTID:244485009
xref: UMLS:C0935626 {source="ncithesaurus:Organ_of_the_Special_Sense"}
xref: VHOG:0001407
xref: WBbt:0006929
is_a: UBERON:0000062 ! organ
intersection_of: UBERON:0000062 ! organ
intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception
relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception
relationship: part_of UBERON:0001032 ! sensory system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray722.png" xsd:anyURI
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall

[Term]
id: UBERON:0000025
name: tube
namespace: uberon
def: "Any hollow cylindrical anatomical structure containing a lumen through which substances are transported." [http://orcid.org/0000-0002-6601-2165]
synonym: "anatomical tube" EXACT []
synonym: "duct" NARROW []
xref: galen:Tube
is_a: UBERON:0004111 ! anatomical conduit
intersection_of: UBERON:0004111 ! anatomical conduit
intersection_of: has_quality PATO:0002299 ! tubular
relationship: has_part UBERON:0013522 ! subdivision of tube
relationship: has_quality PATO:0002299 ! tubular
property_value: curator_notes "not every anatomical conduit is a tube - for example, a bone foramen is an opening in the bone, and there is no distinct separate tube structure. Tubes may transport large mixed objects (for example, a bolus of food in the digestive tube) or they may transport the secretions of a single gland (for example, gland ducts)" xsd:string
property_value: UBPROP:0000007 "tubular" xsd:string

[Term]
id: UBERON:0000026
name: appendage
namespace: uberon
def: "Major subdivision of an organism that protrudes from the body[DOS, CARO]." [CARO:DOS]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "appendages" RELATED OMO:0003004 [XAO:0000218]
synonym: "extremitaet" RELATED [BTO:0001492]
synonym: "extremity" RELATED []
synonym: "limbs/digits/tail" RELATED [MP:0000001]
xref: AEO:0000193
xref: BILA:0000018
xref: BTO:0001492
xref: CARO:0010003
xref: EFO:0000799
xref: EHDAA2:0003193
xref: EMAPA:37283 {source="MA:th"}
xref: EV:0100155
xref: FBbt:00007000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: HAO:0000144
xref: MAT:0000023
xref: MESH:D005121
xref: MIAA:0000023
xref: NCIT:C61460
xref: UMLS:C0598782 {source="ncithesaurus:Appendage"}
xref: VSAO:0000075
xref: Wikipedia:Appendage
xref: XAO:0000218
is_a: UBERON:0000475 ! organism subdivision
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: UBPROP:0000001 "An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs[BILA][BILA:0000018]." xsd:string {source="BILA:0000018"}
property_value: UBPROP:0000001 "Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified][GO:0048736]." xsd:string {source="GO:0048736"}
property_value: UBPROP:0000007 "appendicular" xsd:string
property_value: UBPROP:0000008 "this is currently a subtype of organism subdivision - which would exclude feathers" xsd:string

[Term]
id: UBERON:0000030
name: lamina propria
namespace: uberon
def: "A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions." [Wikipedia:Lamina_propria]
subset: uberon_slim
synonym: "lamina propria mucosa" EXACT []
synonym: "lamina propria mucosae" EXACT []
synonym: "tunica propria" RELATED [BTO:0002330]
xref: BTO:0002330
xref: FMA:62517
xref: NCIT:C32918
xref: SCTID:298225002
xref: UMLS:C1179187 {source="ncithesaurus:Lamina_Propria"}
xref: Wikipedia:Lamina_propria
is_a: UBERON:0004923 ! organ component layer
relationship: composed_primarily_of UBERON:0011825 ! loose connective tissue
relationship: immediately_deep_to UBERON:0000483 ! epithelium
relationship: part_of UBERON:0000344 ! mucosa
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/f/fb/GI_Organization.svg" xsd:anyURI

[Term]
id: UBERON:0000031
name: lamina propria of trachea
namespace: uberon
def: "A lamina propria that is part of a respiratory airway." [OBOL:automatic]
synonym: "lamina propria mucosa of trachea" EXACT [OBOL:automatic]
synonym: "lamina propria mucosa of windpipe" EXACT [OBOL:automatic]
synonym: "lamina propria mucosae of trachea" EXACT [OBOL:automatic]
synonym: "lamina propria mucosae of windpipe" EXACT [OBOL:automatic]
synonym: "lamina propria of windpipe" EXACT [OBOL:automatic]
synonym: "trachea lamina propria" EXACT []
synonym: "trachea lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "trachea lamina propria mucosae" EXACT [OBOL:automatic]
synonym: "tracheal lamina propria" EXACT []
synonym: "windpipe lamina propria" EXACT [OBOL:automatic]
synonym: "windpipe lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "windpipe lamina propria mucosae" EXACT [OBOL:automatic]
xref: EMAPA:35877
xref: FMA:265157
xref: MA:0001858
xref: NCIT:C49305
xref: UMLS:C1710457 {source="ncithesaurus:Trachea_Lamina_Propria"}
is_a: UBERON:0004779 ! respiratory system lamina propria
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0001005 ! respiratory airway
relationship: part_of UBERON:0000379 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! tracheal mucosa

[Term]
id: UBERON:0000033
name: head
namespace: uberon
def: "The head is the anterior-most division of the body [GO]." [GO:0060322, Wikipedia:Head]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "adult head" NARROW []
synonym: "cephalic area" RELATED [SPD:0000016]
synonym: "head (volume)" EXACT [FMA:7154]
xref: AAO:0010335
xref: AEO:0000106
xref: BILA:0000115
xref: BIRNLEX:1230
xref: BTO:0000282
xref: CALOHA:TS-0436
xref: EFO:0000964
xref: EHDAA2:0003106
xref: EMAPA:31858
xref: FMA:7154
xref: GAID:61
xref: galen:Head
xref: HAO:0000397
xref: MA:0000023
xref: MAT:0000294
xref: MESH:D006257
xref: MIAA:0000294
xref: NCIT:C12419
xref: SCTID:302548004
xref: SPD:0000016
xref: TAO:0001114
xref: TGMA:0000002
xref: UMLS:C0018670 {source="ncithesaurus:Head", source="BIRNLEX:1230"}
xref: VHOG:0001644
xref: WBbt:0005739
xref: Wikipedia:Head
xref: XAO:0003024
xref: ZFA:0001114
is_a: UBERON:0011676 ! subdivision of organism along main body axis
relationship: has_skeleton UBERON:0003129 {gci_relation="part_of", gci_filler="NCBITaxon:7776"} ! skull
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
relationship: part_of UBERON:0007811 ! craniocervical region
property_value: RO:0002171 UBERON:0000948
property_value: UBPROP:0000001 "Organism subdivision that is the part of the body consisting of the cranial and pharyngeal regions.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010335", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "Organism subdivision which is the part of the body which consists of the cranial and pharygeal regions.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001114", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "Vertebrate evolution has been characterized by a fresh and vast array of cranial structures that collectively form the head.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001644", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.82", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000042
name: serous membrane
namespace: uberon
def: "Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Serous_membrane]
subset: uberon_slim
subset: vertebrate_core
synonym: "serosa" RELATED [Wikipedia:Serous_membrane]
synonym: "tunica serosa" EXACT OMO:0003011 [FMA:9581]
synonym: "wall of serous sac" EXACT [FMA:9581]
xref: FMA:9581
xref: GAID:19
xref: MESH:D012704
xref: NCIT:C13169
xref: SCTID:362878009
xref: TAO:0005425
xref: UMLS:C0036760 {source="ncithesaurus:Serosa"}
xref: Wikipedia:Serous_membrane
xref: ZFA:0005425
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000481 ! multi-tissue structure
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: has_part UBERON:0001136 ! mesothelium
relationship: has_part UBERON:0002384 ! connective tissue
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000060 ! anatomical wall
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: UBPROP:0000001 "A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005425", ontology="TAO", source="Wikipedia:Serous_membrane"}
property_value: UBPROP:0000001 "a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]" xsd:string {source="Wikipedia:Serous_membrane"}
property_value: UBPROP:0000012 "in FMA, SM = mesothelium + connective tissue. It excludes the cavity. Serous sac = SM + cavity. Note that the SM is a subtype of wall in FMA." xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0000043
name: tendon
namespace: uberon
def: "Dense regular connective tissue that connects muscle to bone[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000073, Wikipedia:Tendon]
subset: pheno_slim
subset: uberon_slim
synonym: "sinew" RELATED [Wikipedia:Tendon]
synonym: "tendo" RELATED OMO:0003011 [Wikipedia:Tendon]
xref: AEO:0000091
xref: BTO:0001356
xref: CALOHA:TS-1021
xref: EHDAA2:0003091
xref: EMAPA:35854
xref: EV:0100149
xref: FMA:9721
xref: GAID:276
xref: galen:Tendon
xref: MA:0000115
xref: MESH:D013710
xref: NCIT:C13045
xref: SCTID:256667004
xref: UMLS:C0039508 {source="ncithesaurus:Tendon"}
xref: VHOG:0001286
xref: VSAO:0000073
xref: Wikipedia:Tendon
xref: XAO:0000173
xref: ZFA:0005647
is_a: UBERON:0007846 {source="VSAO"} ! dense regular connective tissue
relationship: connects UBERON:0001474 ! bone element
relationship: connects UBERON:0001630 ! muscle organ
relationship: has_part CL:0000327 {source="AEO"} ! extracellular matrix secreting cell
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0002204 {source="OG"} ! musculoskeletal system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg" xsd:anyURI
property_value: UBPROP:0000001 "Dense regular connective tissue that connects muscle to bone.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000073", ontology="VSAO", source="PSPUB:0000170"}
property_value: UBPROP:0000003 "Phylogenetically, tendinous tissue first appears in the invertebrate chordate Branchiostoma as myosepta. This two-dimensional array of collagen fibers is highly organized, with fibers running along two primary axes. In hagfish the first linear tendons appear and the myosepta have developed specialized regions with unidirectional fiber orientation - a linear tendon within the flat sheet of myoseptum.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001286", ontology="VHOG", source="DOI:10.1016/S1095-6433(02)00241-6 Summers AP, Koob TJ, The evolution of tendon - morphology and material properties. Comparative Biochemistry and Physiology-Part A: Molecular and Integrative Physiology (2002)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "in FMA, tendon is an organ component that with parts dense-irregular-connective-tissue of tendon and dense-irregular-connective-tissue of tendon sheath; we follow VSAO in making it a subtype of the former. In VSAO tendons connect muscle to bone; in WP the def states integument (e.g. auricular muscles) - but JB confirms this is not actually tendon but aponeurosis" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0000045
name: ganglion
namespace: uberon
def: "A biological tissue mass, most commonly a mass of nerve cell bodies." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Ganglion]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "ganglia" RELATED []
synonym: "neural ganglion" RELATED [BTO:0000497]
xref: AAO:0010426
xref: AEO:0000135
xref: BAMS:G
xref: BTO:0000497
xref: CALOHA:TS-0397
xref: EFO:0000899
xref: EHDAA2:0003135
xref: EHDAA:2897
xref: EHDAA:4662
xref: EHDAA:5621
xref: EHDAA:918
xref: EMAPA:32846
xref: EV:0100372
xref: FMA:5884
xref: MA:0002406
xref: MAT:0000207
xref: MAT:0000343
xref: MESH:D005724
xref: MIAA:0000207
xref: MIAA:0000343
xref: NCIT:C12719
xref: NLXANAT:100302
xref: TAO:0000190
xref: TGMA:0001016
xref: UMLS:C0017067 {source="ncithesaurus:Ganglion"}
xref: VHOG:0000156
xref: WBbt:0005189
xref: Wikipedia:Ganglion
xref: XAO:0000209
xref: ZFA:0000190
is_a: UBERON:0000061 {source="https://github.com/obophenotype/uberon/issues/2495#issuecomment-1187364719"} ! anatomical structure
relationship: composed_primarily_of UBERON:0003714 {source="EHDAA2"} ! neural tissue
relationship: develops_from UBERON:0003869 ! presumptive ganglion
relationship: immediate_transformation_of UBERON:0003869 {source="Bgee:AN"} ! presumptive ganglion
relationship: part_of UBERON:0001016 ! nervous system
property_value: editor_note "TODO - check vert vs invert. Other species: Any of a number of aggregations of neurons, glial cells and their processes, surrounded by a glial cell and connective tissue sheath (plural: ganglia). // Subdivision of neural tree (organ) which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord); together with a nucleus and its associated nerve, it constitutes a neural tree (organ). Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion. // a cluster of nerve cells and associated glial cells (nuclear location) // Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system." xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A ganglion is a cluster of neurons. It is part of a nervous system. It may include glial cells. The neurons are arranged in a specific constellation: neuronal somata are concentrated at the surface, thus forming a cell cortex, and neurites are concentrated in the centre of the ganglion to form the neuropil. A ganglion is a distinct unit but several ganglia may be anterio-posteriorly joined by connectives or transversally by commissures" xsd:string {source="PMID:21062451"}
property_value: UBPROP:0000001 "Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010426", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "Structures containing a collection of nerve cell bodies. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000190", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Subdivision of nervous system which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord. Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion (adapted from Foundational Model of Anatomy)[NLXANAT:100302]." xsd:string {source="NLXANAT:100302"}
property_value: UBPROP:0000003 "Cranial sensory placodes are focused areas of the head ectoderm of vertebrates that contribute to the development of the cranial sense organs and their associated ganglia. Placodes have long been considered a key character of vertebrates, and their evolution is proposed to have been essential for the evolution of an active predatory lifestyle by early vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000156", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.021 Mazet F, Hutt JA, Milloz J, Millard J, Graham A, Shimeld SM, Molecular evidence from Ciona intestinalis for the evolutionary origin of vertebrate sensory placodes. Developmental Biology (2005)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "ganglionic" xsd:string

[Term]
id: UBERON:0000046
name: stemma
name: stemma {def="Eye-spots which may be set into a pit to reduce the angles of light that enters and affects the eyespot, to allow the organism to deduce the angle of incoming light. \n[http://en.wikipedia.org/wiki/Stemma http://en.wikipedia.org/wiki/Eye#Pit_eyes]"}
namespace: uberon
def: "Eye-spots which may be set into a pit to reduce the angles of light that enters and affects the eyespot, to allow the organism to deduce the angle of incoming light." [Wikipedia:Eye#Pit_eyes, Wikipedia:Stemma]
subset: uberon_slim
synonym: "pit eye" EXACT [Wikipedia:Eye#Pit_eyes]
xref: Wikipedia:Stemma
is_a: UBERON:0000047 ! simple eye
property_value: AISM:0000171 "Beutel RG, Friedrich F, Yang X-K, Ge S-Q (2014) Insect Morphology and Phylogeny Insect morphology and phylogeny: a textbook for students of entomology. De Gruyter.\n\nhttps://doi.org/10.1515/9783110264043\n\n\"Stemmata are specific lateral eyes (the term “lateral ocelli” is inappropriate) of larvae of most groups of Holometabola. They are replaced by the adult compound eyes during the metamorphosis. The number ranges between seven and one and they are absent in different groups. Structurally, they resemble ommatidia and are suitable to perceive movements, directions and distances.\"" xsd:string
property_value: RO:0002161 NCBITaxon:7742

[Term]
id: UBERON:0000047
name: simple eye
namespace: uberon
def: "An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity." [Wikipedia:Eye#Simple_eyes]
subset: grouping_class
subset: uberon_slim
xref: TGMA:0000729
xref: Wikipedia:Eye#Simple_eyes
is_a: UBERON:0000970 ! eye

[Term]
id: UBERON:0000055
name: vessel
namespace: uberon
def: "A tubular structure that contains, conveys body fluid, such as blood or lymph." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
subset: human_reference_atlas
subset: pheno_slim
is_a: UBERON:0004111 ! anatomical conduit
relationship: channel_for UBERON:0006314 ! bodily fluid
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000056
name: ureter
namespace: uberon
def: "Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs." [GO:0090189, Wikipedia:Ureter]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "metanephric duct" RELATED [ISBN:0073040584, VHOG:0000605]
xref: AAO:0010254
xref: BTO:0001409
xref: CALOHA:TS-1084
xref: EFO:0000930
xref: EHDAA2:0002139
xref: EHDAA:9341
xref: EMAPA:17950
xref: EV:0100097
xref: FMA:9704
xref: GAID:438
xref: galen:Ureter
xref: MA:0000378
xref: MAT:0000120
xref: MESH:D014513
xref: MIAA:0000120
xref: NCIT:C12416
xref: SCTID:302511008
xref: UMLS:C0041951 {source="ncithesaurus:Ureter"}
xref: VHOG:0000605
xref: Wikipedia:Ureter
xref: XAO:0000144
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005179 ! pelvic region element
is_a: UBERON:0006555 ! excretory tube
is_a: UBERON:0015212 ! lateral structure
relationship: channel_for UBERON:0001088 ! urine
relationship: channels_from UBERON:0001224 ! renal pelvis
relationship: channels_into UBERON:0001255 ! urinary bladder
relationship: develops_from UBERON:0005081 {source="GO"} ! ureter ureteric bud
relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism
relationship: part_of UBERON:0036295 ! renal pelvis/ureter
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anatomical structure consisting of long narrow duct which carries urine from the kidney to the urinary bladder.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010254", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The duct of amniotes that carries urine from a metanephric kidney to the urinary bladder. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000605", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000605", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "ureteral" xsd:string
property_value: UBPROP:0000007 "ureteric" xsd:string
property_value: UBPROP:0000010 "in humans, consists of adventitial, muscular and mucoa layers" xsd:string

[Term]
id: UBERON:0000057
name: urethra
namespace: uberon
def: "The fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening." [MGI:anna, MP:0000537]
subset: efo_slim
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
xref: BTO:0001426
xref: CALOHA:TS-1132
xref: EFO:0000931
xref: EMAPA:30901
xref: EV:0100099
xref: FMA:19667
xref: GAID:390
xref: galen:Urethra
xref: MA:0000379
xref: MAT:0000121
xref: MESH:D014521
xref: MIAA:0000121
xref: NCIT:C12417
xref: SCTID:302513006
xref: UMLS:C0041967 {source="ncithesaurus:Urethra"}
xref: VHOG:0001264
xref: Wikipedia:Urethra
xref: XAO:0000153
is_a: UBERON:0000062 ! organ
is_a: UBERON:0004111 ! anatomical conduit
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: capable_of_part_of GO:0060073 ! micturition
relationship: channel_for UBERON:0001088 ! urine
relationship: channels_from UBERON:0001255 ! urinary bladder
relationship: continuous_with UBERON:0001255 ! urinary bladder
relationship: develops_from UBERON:0000164 {notes="pelvic part of UG sinus gives rise to prostatic and membranous parts of urethra", source="Wikipedia"} ! primitive urogenital sinus
relationship: develops_from UBERON:0013241 {source="Wikipedia"} ! embryonic urethral groove
relationship: part_of UBERON:0001556 ! lower urinary tract
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI
property_value: UBPROP:0000007 "urethral" xsd:string
property_value: UBPROP:0000008 "In human males, the urethra travels through the penis, and carries semen as well as urine. In females, the urethra is shorter and emerges above the vaginal opening." xsd:string

[Term]
id: UBERON:0000058
name: duct
namespace: uberon
def: "A tubular structure that transports secreted or excreted substances." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm#ducts]
subset: grouping_class
synonym: "anatomical duct" EXACT []
synonym: "ducts" RELATED OMO:0003004 [XAO:0004000]
synonym: "exocrine duct" NARROW []
synonym: "exocrine gland duct" NARROW []
xref: AAO:0011123
xref: FBbt:00100314 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:30320
xref: galen:Duct
xref: NCIT:C12948
xref: SCTID:91726008
xref: TAO:0005171
xref: UMLS:C0687028 {source="ncithesaurus:Duct"}
xref: Wikipedia:Duct_(anatomy)
xref: XAO:0004000
xref: ZFA:0005171
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000063 ! organ subunit
relationship: conduit_for UBERON:0000463 ! organism substance
relationship: has_part UBERON:0034969 ! epithelial layer of duct
relationship: has_quality PATO:0002299 ! tubular
property_value: UBPROP:0000001 "A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination[ZFA:0005171]." xsd:string {source="ZFA:0005171"}
property_value: UBPROP:0000012 "Most ducts, but not all, are exocrine gland ducts. Some ontologies classify structures such as the oviduct here." xsd:string

[Term]
id: UBERON:0000059
name: large intestine
namespace: uberon
def: "A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]." [ISBN:0073040584, Wikipedia:Large_intestine_(anatomy)]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
synonym: "intestinum crassum" RELATED [BTO:0000706]
xref: AAO:0010396
xref: BTO:0000706
xref: CALOHA:TS-1306
xref: EFO:0000840
xref: EMAPA:19252
xref: EV:0100077
xref: FMA:7201
xref: GAID:306
xref: galen:LargeIntestine
xref: MA:0000333
xref: MESH:D007420
xref: MIAA:0000046
xref: NCIT:C12379
xref: SCTID:181254001
xref: UMLS:C0021851 {source="ncithesaurus:Large_Intestine"}
xref: VHOG:0000054
xref: Wikipedia:Large_intestine_(anatomy)
xref: XAO:0000131
is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract
is_a: UBERON:0013765 ! digestive system element
relationship: contributes_to_morphology_of UBERON:0000160 ! intestine
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0004907 ! lower digestive tract
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/SBU_F_Intestine_Large.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "Intestinal surface area also is increased in amphibians and reptiles by internal folds and occasionally by a few villi. The intestine can be divided into a small intestine and a slightly wider large intestine.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000054", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.566", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000060
name: anatomical wall
namespace: uberon
alt_id: UBERON:0009915
def: "Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers." [FMA:82482]
subset: upper_level
synonym: "organ wall" RELATED [FMA:82482]
synonym: "wall" BROAD []
synonym: "wall of organ" EXACT [FMA:82482]
xref: EMAPA:25036
xref: FMA:82482
xref: galen:Wall
is_a: UBERON:0000064 ! organ part
relationship: adjacent_to UBERON:0002553 ! anatomical cavity
relationship: has_part UBERON:0004923 ! organ component layer
property_value: UBPROP:0000012 "in FMA, serosa is a wall" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0000061
name: anatomical structure
namespace: uberon
def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CARO:0000003]
subset: common_anatomy
subset: upper_level
synonym: "biological structure" EXACT []
synonym: "connected biological structure" EXACT [CARO:0000003]
xref: AAO:0010825
xref: AEO:0000003
xref: BILA:0000003
xref: CARO:0000003
xref: EHDAA2:0003003
xref: EMAPA:0
xref: FBbt:00007001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:305751
xref: FMA:67135
xref: GAID:781
xref: HAO:0000003
xref: http://dbpedia.org/ontology/AnatomicalStructure
xref: MA:0003000
xref: MESH:D000825
xref: SCTID:362889002
xref: TAO:0000037
xref: TGMA:0001823
xref: VHOG:0001759
xref: XAO:0003000
xref: ZFA:0000037
is_a: UBERON:0000465 ! material anatomical entity
relationship: existence_ends_during_or_before UBERON:0000071 ! death stage
relationship: existence_starts_during_or_after UBERON:0000106 {gci_relation="in_taxon", gci_filler="NCBITaxon:33208"} ! zygote stage
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000062
name: organ
namespace: uberon
def: "Anatomical structure that performs a specific function or group of functions [WP]." [Wikipedia:Organ_(anatomy)]
subset: common_anatomy
subset: upper_level
synonym: "anatomical unit" RELATED []
synonym: "body organ" RELATED []
synonym: "element" RELATED [http://orcid.org/0000-0002-6601-2165]
xref: BIRNLEX:4
xref: CARO:0020004
xref: EFO:0000634
xref: EMAPA:35949
xref: ENVO:01000162
xref: FMA:67498
xref: MA:0003001
xref: NCIT:C13018
xref: SCTID:272625005
xref: UMLS:C0178784 {source="ncithesaurus:Organ"}
xref: WBbt:0003760
xref: Wikipedia:Organ_(anatomy)
is_a: UBERON:0010000 ! multicellular anatomical structure
disjoint_from: UBERON:0002095 {source="PMID:28192867"} ! mesentery
disjoint_from: UBERON:0034921 ! multi organ part structure
relationship: capable_of GO:0008150 ! biological process
relationship: existence_starts_during_or_after UBERON:0000111 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! organogenesis stage
relationship: has_boundary UBERON:0006984 ! anatomical surface
relationship: part_of UBERON:0000467 ! anatomical system
property_value: RO:0002161 NCBITaxon:110815 {source="Wikipedia"}
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751
property_value: UBPROP:0000001 "Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." xsd:string {source="GO:0048513"}
property_value: UBPROP:0000012 "CARO v1 does not include a generic 'organ' class, only simple and compound organ. CARO v2 may include organ, see https://github.com/obophenotype/caro/issues/4" xsd:string

[Term]
id: UBERON:0000063
name: organ subunit
namespace: uberon
def: "A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity." [http://orcid.org/0000-0002-6601-2165]
subset: upper_level
synonym: "organ region with fixed fiat boundary" RELATED [FMA:86140]
synonym: "organ segment" RELATED [FMA:86140]
synonym: "segment of organ" RELATED [FMA:86140]
xref: FMA:86140
is_a: UBERON:0000064 ! organ part
property_value: editor_note "FMA distinguishes segment from zone by whether the fiat boundaries are fixed/anchored (segments) or floating (zone). It's not completely clear how to apply this distinction" xsd:string
property_value: UBPROP:0000001 "Organ region with one or more anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyeball." xsd:string {source="FMA:86140", version="3"}
property_value: UBPROP:0000001 "Organ region with one or more fixed or anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyebal." xsd:string {source="FMA:86140", version="1"}

[Term]
id: UBERON:0000064
name: organ part
namespace: uberon
def: "A multicellular structure that is a part of an organ." [http://orcid.org/0000-0002-6601-2165]
subset: common_anatomy
subset: efo_slim
subset: non_informative
subset: upper_level
synonym: "cardinal organ part" EXACT [FMA:82472]
synonym: "regional part of organ" RELATED [BIRNLEX:16]
xref: AAO:0011124
xref: BIRNLEX:16
xref: EFO:0000635
xref: FMA:82472
xref: SCTID:113343008
xref: SCTID:91717005
is_a: UBERON:0010000 ! multicellular anatomical structure
relationship: part_of UBERON:0000062 ! organ
property_value: curator_notes "currently defined in a very broad sense, may be replaced by more specific classes in the future" xsd:string
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000065
name: respiratory tract
namespace: uberon
def: "Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts." [https://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
xref: EHDAA2:0001606
xref: EHDAA:1568
xref: EHDAA:2219
xref: EMAPA:16737
xref: FMA:265130
xref: SCTID:361110005
xref: VHOG:0000393
is_a: UBERON:0001005 ! respiratory airway
is_a: UBERON:0004119 ! endoderm-derived structure
relationship: develops_from UBERON:0007026 {source="NCBIBook:NBK10107"} ! presumptive gut
relationship: develops_from UBERON:0008947 ! respiratory primordium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000066
name: fully formed stage
namespace: uberon
def: "The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage." [https://orcid.org/0000-0002-6601-2165]
subset: efo_slim
synonym: "adult stage" BROAD []
synonym: "fully formed animal stage" EXACT []
synonym: "juvenile-adult stage" EXACT []
xref: BilaDO:0000004
xref: BTO:0001043
xref: EFO:0001272
xref: FBdv:00005369
xref: WBls:0000041
xref: XtroDO:0000084
is_a: UBERON:0000105 ! life cycle stage
relationship: part_of UBERON:0000092 ! post-embryonic stage
relationship: preceded_by UBERON:0000111 ! organogenesis stage
relationship: preceded_by UBERON:0004729 {gci_relation="part_of", gci_filler="NCBITaxon:6239"} ! nematode larval stage
relationship: precedes UBERON:0000071 ! death stage
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/566" xsd:anyURI

[Term]
id: UBERON:0000068
name: embryo stage
namespace: uberon
def: "A life cycle stage that starts with fertilization and ends with the fully formed embryo." [http://orcid.org/0000-0002-6601-2165]
synonym: "embryogenesis" RELATED []
synonym: "embryonic stage" EXACT []
xref: BilaDO:0000002
xref: EV:0300001
xref: FBdv:00005289
xref: FMA:72652
xref: HsapDv:0000002
xref: MmusDv:0000002
xref: OGES:000000
xref: OGES:000022
xref: SCTID:296280003
xref: WBls:0000003
xref: WBls:0000092
xref: WBls:0000102
xref: XAO:1000012
is_a: UBERON:0000105 ! life cycle stage
disjoint_from: UBERON:0000092 ! post-embryonic stage
relationship: precedes UBERON:0000066 ! fully formed stage
relationship: precedes UBERON:0000092 ! post-embryonic stage
relationship: simultaneous_with GO:0009790 ! embryo development

[Term]
id: UBERON:0000069
name: larval stage
namespace: uberon
def: "A distinct juvenile stage many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle." [Wikipedia:Larva]
subset: efo_slim
synonym: "ammocoete" NARROW SENSU [Wikipedia:Larva]
synonym: "ammocoete stage" NARROW SENSU [Wikipedia:Larva]
synonym: "bipinnaria" NARROW SENSU [Wikipedia:Larva]
synonym: "bipinnaria stage" NARROW SENSU [Wikipedia:Larva]
synonym: "caterpillar" NARROW SENSU [Wikipedia:Larva]
synonym: "caterpillar stage" NARROW SENSU [Wikipedia:Larva]
synonym: "glochidium" NARROW SENSU [Wikipedia:Larva]
synonym: "glochidium stage" NARROW SENSU [Wikipedia:Larva]
synonym: "grub" NARROW SENSU [Wikipedia:Larva]
synonym: "grub stage" NARROW SENSU [Wikipedia:Larva]
synonym: "larva" RELATED []
synonym: "larva stage" EXACT []
synonym: "leptocephalus" NARROW SENSU [Wikipedia:Larva]
synonym: "leptocephalus stage" NARROW SENSU [Wikipedia:Larva]
synonym: "maggot" NARROW SENSU [Wikipedia:Larva]
synonym: "maggot stage" NARROW SENSU [Wikipedia:Larva]
synonym: "metacestode" NARROW SENSU [BTO:0000859]
synonym: "naiad, nymph" NARROW SENSU [Wikipedia:Larva]
synonym: "naiad, nymph stage" NARROW SENSU [Wikipedia:Larva]
synonym: "nauplius" NARROW SENSU [Wikipedia:Larva]
synonym: "nauplius stage" NARROW SENSU [Wikipedia:Larva]
synonym: "nymph" NARROW SENSU [Wikipedia:Larva]
synonym: "nymph stage" NARROW SENSU [Wikipedia:Larva]
synonym: "planula" NARROW SENSU [Wikipedia:Larva]
synonym: "planula stage" NARROW SENSU [Wikipedia:Larva]
synonym: "tornaria" NARROW SENSU [NCBITaxon:10219]
synonym: "trochophore" NARROW SENSU [Wikipedia:Larva]
synonym: "trochophore stage" NARROW SENSU [Wikipedia:Larva]
synonym: "veliger" NARROW SENSU [Wikipedia:Larva]
synonym: "veliger stage" NARROW SENSU [Wikipedia:Larva]
synonym: "wriggler" NARROW SENSU [Wikipedia:Larva]
synonym: "wriggler stage" NARROW SENSU [Wikipedia:Larva]
synonym: "zoea" NARROW SENSU [Wikipedia:Larva]
synonym: "zoea stage" NARROW SENSU [Wikipedia:Larva]
xref: BTO:0000915
xref: BTO:0000954
xref: EFO:0001303
xref: FBdv:00005336
xref: MIAA:0000400
xref: OGES:000008
xref: Wikipedia:Larva
xref: ZFS:0000048
is_a: UBERON:0000105 ! life cycle stage
relationship: immediately_preceded_by UBERON:0000068 ! embryo stage
relationship: part_of UBERON:0000092 ! post-embryonic stage
relationship: simultaneous_with GO:0002164 ! larval development
property_value: curator_notes "Uberon includes clade-specific subclasses, e.g. nematod larva" xsd:string
property_value: RO:0002161 NCBITaxon:32524
property_value: UBPROP:0000008 "It is a misunderstanding that the larval form always reflects the group's evolutionary history. It could be the case, but often the larval stage has evolved secondarily, as in insects. In these cases the larval form might differ more from the group's common origin than the adult form" xsd:string {source="WP"}

[Term]
id: UBERON:0000071
name: death stage
namespace: uberon
def: "End of the life of an organism." [XAO:0000437]
subset: common_anatomy
synonym: "death" RELATED []
xref: XAO:0000437
xref: XtroDO:0000085
is_a: UBERON:0000105 ! life cycle stage
relationship: ends UBERON:0000104 ! life cycle
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751
property_value: UBPROP:0000012 "ncit:Death is an outcome" xsd:string {external_ontology="ncit"}

[Term]
id: UBERON:0000072
name: proximo-distal subdivision of respiratory tract
namespace: uberon
def: "An section of a respiratory tract." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
synonym: "respiratory tract" RELATED [MA:0000434]
synonym: "subdivision of respiratory tract" RELATED []
xref: EMAPA:16737
xref: FMA:45660
xref: MA:0000434
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0013522 ! subdivision of tube
intersection_of: UBERON:0013522 ! subdivision of tube
intersection_of: part_of UBERON:0000065 ! respiratory tract
relationship: part_of UBERON:0000065 ! respiratory tract
property_value: UBPROP:0000012 "MA:0000434 has subclasses upper and lower, so it corresponds to a segment of the tract, rather than the tract as a whole" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0000073
name: regional part of nervous system
namespace: uberon
def: "Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS." [BIRNLEX:1157]
subset: non_informative
subset: upper_level
synonym: "part of nervous system" EXACT [BIRNLEX:1157]
xref: BIRNLEX:1157
xref: NCIT:C13040
xref: SCTID:25087005
xref: UMLS:C1518256 {source="ncithesaurus:Nervous_System_Part"}
is_a: UBERON:0000481 ! multi-tissue structure
intersection_of: UBERON:0000481 ! multi-tissue structure
intersection_of: part_of UBERON:0001016 ! nervous system
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0001016 ! nervous system
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-9114-8737
creation_date: 2009-06-18T09:00:04Z

[Term]
id: UBERON:0000075
name: subdivision of skeletal system
namespace: uberon
alt_id: UBERON:0010322
def: "Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003]
subset: non_informative
synonym: "skeletal system part" RELATED []
synonym: "skeletal system subdivision" EXACT [FMA:85544]
xref: FMA:85544
xref: galen:ComplexSkeletalStructure
xref: NCIT:C34076
xref: SCTID:118966000
xref: UMLS:C1519343 {source="ncithesaurus:Skeletal_System_Part"}
is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision
relationship: composed_primarily_of UBERON:0004765 ! skeletal element
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
relationship: part_of UBERON:0001434 ! skeletal system

[Term]
id: UBERON:0000076
name: external ectoderm
namespace: uberon
def: "The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm." [MGI:anna, MP:0012532]
subset: pheno_slim
synonym: "surface (external) ectoderm" EXACT []
synonym: "surface ectoderm" EXACT [MP:0012532]
xref: BTO:0006242 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: EHDAA2:0001968
xref: EHDAA:1494
xref: EHDAA:350
xref: EHDAA:4784
xref: EHDAA:4790
xref: EHDAA:4796
xref: EHDAA:7860
xref: EMAPA:16096
xref: FMA:87656
xref: NCIT:C34309
xref: UMLS:C1515087 {source="ncithesaurus:Surface_Ectoderm"}
xref: Wikipedia:External_ectoderm
is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium
is_a: UBERON:0005291 ! embryonic tissue
relationship: part_of UBERON:0000924 {source="EHDAA2"} ! ectoderm
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1d/Ectoderm.png" xsd:anyURI
property_value: editor_note "merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube)" xsd:string
property_value: RO:0002171 UBERON:0002346
property_value: UBPROP:0000011 "(or external ectoderm) forms the following structures: Skin Epithelium of the mouth and nasal cavity saliavary glands, and glands of mouth and nasal cavity Enamel - as a side note dentin and dental pulp are formed from ectomesenchyme which is derived from ectoderm Epithelium of pineal and pituitary glands Lens and cornea of the eye Apical ectodermal ridge inducing development of the limb buds of the embryo. Sensory receptors in epidermis" xsd:string

[Term]
id: UBERON:0000077
name: mixed endoderm/mesoderm-derived structure
namespace: uberon
def: "An anatomical structure that develops from the endoderm and the mesoderm." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: develops_from UBERON:0000925 ! endoderm
intersection_of: develops_from UBERON:0000926 ! mesoderm
property_value: curator_notes "Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple" xsd:string

[Term]
id: UBERON:0000078
name: mixed ectoderm/mesoderm/endoderm-derived structure
namespace: uberon
def: "An anatomical structure that develops from the ectoderm, mesoderm and endoderm." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: develops_from UBERON:0000924 ! ectoderm
intersection_of: develops_from UBERON:0000925 ! endoderm
intersection_of: develops_from UBERON:0000926 ! mesoderm
property_value: curator_notes "Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple" xsd:string

[Term]
id: UBERON:0000079
name: male reproductive system
namespace: uberon
def: "The organs associated with producing offspring in the gender that produces spermatozoa." [MP:0001145]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
synonym: "genitalia of male organism" EXACT [OBOL:automatic]
synonym: "male genital organ" RELATED [BTO:0000082]
synonym: "male genital system" EXACT [FMA:45664]
synonym: "male genital tract" RELATED []
synonym: "male genitalia" EXACT []
synonym: "male genitals" EXACT []
synonym: "male organism genitalia" EXACT [OBOL:automatic]
synonym: "male organism reproductive system" EXACT [OBOL:automatic]
synonym: "male reproductive tract" RELATED [MA:0000396]
synonym: "reproductive system of male organism" EXACT [OBOL:automatic]
synonym: "systema genitale masculinum" RELATED [BTO:0000082]
xref: BTO:0000082
xref: CALOHA:TS-1310
xref: EFO:0000970
xref: EHDAA2:0001054
xref: EHDAA:8136
xref: EMAPA:17968
xref: EV:0100101
xref: FBbt:00004927 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:45664
xref: GAID:386
xref: HAO:0000505
xref: MA:0000396
xref: MESH:D005837
xref: NCIT:C12722
xref: SCTID:361340001
xref: TGMA:0000634
xref: UMLS:C0017422 {source="ncithesaurus:Male_Genitalia"}
xref: UMLS:C1963704 {source="ncithesaurus:Male_Reproductive_System"}
xref: VHOG:0000725
xref: Wikipedia:Male_reproductive_system_(human)
xref: XAO:0000155
is_a: UBERON:0000990 ! reproductive system
intersection_of: UBERON:0000990 ! reproductive system
intersection_of: part_of UBERON:0003101 ! male organism
disjoint_from: UBERON:0000474 ! female reproductive system
relationship: part_of UBERON:0003101 ! male organism
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "By far, sexual reproduction is the more common pattern among living vertebrate forms and its widespread occurrence suggests that it is the plesiomorphic, or primitive, reproductive mode among the vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000725", ontology="VHOG", source="ISBN:978-0792383369 Lombardi J, Comparative vertebrate reproduction (1998) p.43", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000080
name: mesonephros
namespace: uberon
def: "The second stage of the kidney. It serves as the main excretory organ of aquatic vertebrates and as a temporary embryonic kidney in higher vertebrates. It is composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo." [GO:0001823, Wikipedia:Mesonephros]
subset: efo_slim
subset: organ_slim
subset: pheno_slim
subset: vertebrate_core
synonym: "amphibian adult kidney" RELATED [XAO:0000141]
synonym: "corpus Wolffi" RELATED [BTO:0001542]
synonym: "mesonephric kidney" EXACT [XAO:0000141]
synonym: "mesonephroi" EXACT OMO:0003004 [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron]
synonym: "middle kidney" RELATED [BTO:0001542]
synonym: "opisthonephros" RELATED [VHOG:0000038, XAO:0000141]
synonym: "opisto nephros" RELATED []
synonym: "opistonephros" RELATED [http://www.usm.maine.edu/bio/courses/bio205/bio205_26_sex.html]
synonym: "Wolffian body" EXACT [BTO:0001542, GOC:yaf, MESH:A16.254.500, Wikipedia:Mesonephros]
xref: AAO:0010384
xref: BTO:0001542
xref: CALOHA:TS-0624
xref: EFO:0000928
xref: EHDAA2:0001130
xref: EHDAA:1581
xref: EHDAA:5903
xref: EMAPA:16744
xref: FMA:72171
xref: GAID:1308
xref: MESH:D001755
xref: NCIT:C26467
xref: SCTID:308799002
xref: TAO:0000529
xref: UMLS:C0025492 {source="ncithesaurus:Mesonephros"}
xref: VHOG:0000038
xref: Wikipedia:Mesonephros
xref: XAO:0000141
xref: ZFA:0000529
is_a: UBERON:0002113 ! kidney
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: develops_from UBERON:0002120 ! pronephros
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/ad/Gray986.png" xsd:anyURI
property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the middle region of the nephric ridge; a transient embryonic stage that replaces the pronephros, but is itself replaced by the adult metanephros [in mammals; in fishes and amphibians it is the adult kidney]. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.745][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000038", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000001 "Organ that is the definitive adult kidney. It replaces the earlier pronephros, which degenerates as the mesonephros becomes functional in feeding stage tadpoles.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010384", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "As the pronephros regresses, the archinephric duct induces the sequential differentiation of tubules in the more caudal parts of the nephric ridge. (...) Tubules that differentiate in the middle part of the nephric ridge form a kidney called the mesonephros. This kidney functions in the embryos and larvae of all vertebrates. (...) In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000038", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "mesonephric" xsd:string
property_value: UBPROP:0000008 "In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In fish and amphibians, the mesonephros will form the mature kidney" xsd:string
property_value: UBPROP:0000009 "By contrast to the pronephros, the histological features of the mammalian mesonephros, with its primitive glomeruli, suggest that it probably functions as a primitive kidney, and is involved in the production of much of the amniotic fluid. Within the two mesonephroi, one located on either side of the dorsal mesentery of the hindgut, a substantial number (in the region of about 40 or more) of cranio-caudally segmented mesonephric tubules are formed. It has, however, been suggested that only the most rostrally located 4-6 pairs of mesonephric tubules drain into the mesonephric portion of the nephric duct. This is now seen to extend along the length of the mesonephroi, being located towards their lateral sides. The mesonephros is also retained over a considerably longer period than the pronephros, but gradually undergoes regression in a cranio-caudal direction. While the rostral part displays clear evidence of regression its more caudal part appears to display evidence of functional activity. Within the medial part of the mesonephros, vesicles are formed, although no glomeruli are formed there in this species. It is, however, difficult to believe that the relatively enormous mesonephroi do not have an excretory role in the mouse, only serving as a base for gonadal differentiation. In the human embryo, the medial part of the mesonephric tubules enlarges, become invaginated by capillaries, and form glomeruli. These then take on an excretory role. In the mouse, the mesonephric ducts appear to be patent throughout their length[GUDMAP, modified]" xsd:string

[Term]
id: UBERON:0000081
name: metanephros
namespace: uberon
def: "In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine[GO]." [GO:0001656, Wikipedia:Metanephros#Metanephros]
subset: organ_slim
subset: pheno_slim
synonym: "definite kidney" RELATED [BTO:0001543]
synonym: "definitive kidney" RELATED [BTO:0001543]
synonym: "hind kidney" RELATED [BTO:0001543]
synonym: "metanephric kidney" RELATED [VHOG:0000039]
synonym: "metanephron" EXACT [BTO:0001543]
xref: BTO:0001543
xref: EHDAA2:0001137
xref: EHDAA:3089
xref: EHDAA:5911
xref: EMAPA:17373
xref: EMAPA_RETIRED:17207
xref: FMA:72172
xref: NCIT:C34209
xref: SCTID:308797000
xref: UMLS:C0231049 {source="ncithesaurus:Metanephros"}
xref: VHOG:0000039
xref: Wikipedia:Metanephros#Metanephros
is_a: UBERON:0002113 ! kidney
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: developmentally_replaces UBERON:0000080 {source="ISBN:9780878932504"} ! mesonephros
relationship: develops_from UBERON:0003220 {evidence="definitional"} ! metanephric mesenchyme
relationship: develops_from UBERON:0005080 {source="GO"} ! metanephric ureteric bud
relationship: develops_from UBERON:0005753 ! caudal part of nephrogenic cord
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
property_value: editor_note "TODO check developmental relationships" xsd:string
property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the posterior region of the nephric ridge and drained by a ureter; replaces the embryonic pronephros and mesonephros [in mammals]. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.745][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000039", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000039", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "metanephric" xsd:string
property_value: UBPROP:0000011 "During the fifth week of gestation, the mesonephric duct develops an outpouching, the ureteric bud, near its attachment to the cloaca. This bud, also called the metanephrogenic diverticulum, grows posteriorly and towards the head of the embryo. The elongated stalk of the ureteric bud, the metanephric duct, later forms the ureter. As the cranial end of the bud extends into the intermediate mesoderm, it undergoes a series of branchings to form the collecting duct system of the kidney. It also forms the major and minor calyces and the renal pelvis" xsd:string

[Term]
id: UBERON:0000083
name: mesonephric tubule
namespace: uberon
def: "A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]." [Wikipedia:Mesonephric_tubules]
synonym: "renal tubules" RELATED OMO:0003004 [VHOG:0000500]
synonym: "tubuli mesonephrici" RELATED OMO:0003011 [Wikipedia:Mesonephric_tubules]
xref: AAO:0010389
xref: EHDAA2:0001134
xref: EMAPA:16747
xref: VHOG:0000500
xref: Wikipedia:Mesonephric_tubules
xref: XAO:0000148
is_a: UBERON:0003914 ! epithelial tube
is_a: UBERON:0005103 ! mesonephric epithelium
is_a: UBERON:0006555 ! excretory tube
intersection_of: UBERON:0003914 ! epithelial tube
intersection_of: part_of UBERON:0000080 ! mesonephros
property_value: editor_note "TODO check" xsd:string
property_value: UBPROP:0000001 "Any of the renal tubules composing the mesonephros. In mammals they function as excretory structures during the early embryonic development but are later incorporated into the reproductive system. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000500", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/mesonephric+tubule"}
property_value: UBPROP:0000003 "As the pronephros regresses, the archinephric duct induces the sequential differentiation of tubules in the more caudal parts of the nephric ridge. (...) Tubules that differentiate in the middle part of the nephric ridge form a kidney called the mesonephros. This kidney functions in the embryos and larvae of all vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000500", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000084
name: ureteric bud
namespace: uberon
def: "An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]." [MP:0010979, PMID:19828308]
subset: pheno_slim
synonym: "diverticulum" RELATED [BTO:0001646]
synonym: "diverticulum metanephricum" RELATED OMO:0003011 [Wikipedia:Ureteric_bud]
synonym: "gemma ureterica" RELATED OMO:0003011 [Wikipedia:Ureteric_bud]
synonym: "metanephric bud" RELATED [BTO:0001646]
synonym: "metanephric diverticulum" RELATED [Wikipedia:Metanephros#Metanephros]
synonym: "ureteric ampulla" RELATED []
synonym: "ureteric diverticulum" RELATED [VHOG:0000541]
xref: BTO:0001646
xref: EHDAA2:0002140
xref: EHDAA:3091
xref: EHDAA:5917
xref: EMAPA:17209
xref: NCIT:C34207
xref: SCTID:361528000
xref: UMLS:C1284058 {source="ncithesaurus:Metanephric_Diverticulum"}
xref: VHOG:0000541
xref: Wikipedia:Ureteric_bud
is_a: UBERON:0000083 ! mesonephric tubule
is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac
is_a: UBERON:0034969 ! epithelial layer of duct
relationship: developmentally_induced_by UBERON:0003220 {source="ISBN:9780878932504"} ! metanephric mesenchyme
relationship: develops_from UBERON:0003074 {source="EHDAA2"} ! mesonephric duct
relationship: part_of UBERON:0003074 ! mesonephric duct
property_value: UBPROP:0000001 "Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts. [Embryology, See_Dudek_RW_and_Fix_JD, Third_Edition_(2004)_Philadelphia:_Lippincott_William_and_Wilkins, p.137][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000541", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000001 "Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts[VHOG:0000541]." xsd:string {source="VHOG:0000541"}
property_value: UBPROP:0000003 "The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000541", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000085
name: morula
namespace: uberon
def: "A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum." [MP:0012130]
subset: pheno_slim
synonym: "morula (2-16 cells)" RELATED [EHDAA2:0000005]
xref: BTO:0001508
xref: EHDAA2:0000005
xref: FMA:292334
xref: GAID:1295
xref: MESH:D009028
xref: NCIT:C34212
xref: SCTID:361474003
xref: UMLS:C0026573 {source="ncithesaurus:Morula"}
xref: Wikipedia:Morula
is_a: UBERON:0000922 ! embryo
relationship: existence_ends_during UBERON:0000107 ! cleavage stage
relationship: existence_starts_during UBERON:0000107 ! cleavage stage
relationship: has_part CL:0000353 ! blastoderm cell
relationship: part_of UBERON:0004716 {source="EHDAA2"} ! conceptus
relationship: surrounded_by UBERON:0000086 ! zona pellucida
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI
property_value: UBPROP:0000012 "EHDAA2 has embryo starting later" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0000086
name: zona pellucida
namespace: uberon
def: "A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes." [Wikipedia:Zona_pellucida]
subset: human_reference_atlas
subset: pheno_slim
subset: vertebrate_core
synonym: "oolemma" RELATED [BTO:0003135]
synonym: "pellucid zone" RELATED [BTO:0003135]
synonym: "striated membrane" RELATED [BTO:0003135]
synonym: "vitelline envelope" RELATED []
synonym: "vitelline membrane" RELATED []
synonym: "zona pellucida - vitelline membrane" BROAD [VHOG:0000720]
synonym: "zona radiata" RELATED [BTO:0003135]
synonym: "zona striata" RELATED [BTO:0003135]
xref: BTO:0003135
xref: EHDAA2:0002220
xref: EHDAA:31
xref: EHDAA:62
xref: EMAPA:16035
xref: FMA:18674
xref: GAID:410
xref: MA:0001715
xref: MESH:D015044
xref: NCIT:C33896
xref: TAO:0001111
xref: UMLS:C0043519 {source="ncithesaurus:Zona_Pellucida"}
xref: VHOG:0000720
xref: Wikipedia:Zona_pellucida
xref: ZFA:0001111
is_a: UBERON:0005764 ! acellular membrane
relationship: bounding_layer_of CL:0000023 ! oocyte
relationship: has_part CHEBI:17089 ! glycoprotein
relationship: part_of CL:0000023 ! oocyte
relationship: part_of UBERON:0000992 ! ovary
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray3.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "Outside the plasma membrane, three envelopes surround the ovum. The first, the primary egg envelope, lies between the plasma membrane and the surrounding cells of the ovary. The most consistent component of this primary layer is the vitelline membrane, a transparent jacket of fibrous protein. In mammals, the homologous structure is called the zona pellucida.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000720", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.159", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000087
name: inner cell mass
namespace: uberon
def: "A mass of cells that develop into the body of the embryo and some extraembryonic tissues." [ISBN:0-683-40008-8, MGI:pvb]
subset: early_development
subset: efo_slim
subset: pheno_slim
synonym: "early embryoblast" RELATED [FMA:86557]
synonym: "embryoblast" RELATED []
synonym: "embryoblastus; massa cellularis interna; pluriblastus senior" RELATED OMO:0003011 [Wikipedia:Inner_cell_mass]
synonym: "ICM" RELATED [VHOG:0000742]
synonym: "pluriblast" RELATED []
xref: EFO:0000547
xref: EHDAA2:0000830
xref: EHDAA:40
xref: EMAPA:16041
xref: FMA:86557
xref: NCIT:C13740
xref: SCTID:361456007
xref: UMLS:C1283994 {source="ncithesaurus:Inner_Cell_Mass"}
xref: VHOG:0000742
xref: Wikipedia:Inner_cell_mass
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0000358 {source="Wikipedia"} ! blastocyst
relationship: surrounded_by UBERON:0000088 {source="Wikipedia"} ! trophoblast
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI
property_value: UBPROP:0000001 "A group of cells found in the mammalian blastocyst that give rise to the embryo. [Biology_Online][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000742", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "A small sphere of cells known as the inner cell mass lies within the trophoblast (of all eutherian mammals).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000742", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.144", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "This structure forms in the earliest steps of development, before implantation into the endometrium of the uterus has occurred.The ICM lies within the blastocyst cavity and is entirely surrounded by the single layer of cells called trophoblast. [Wikipedia:Inner_cell_mass]" xsd:string

[Term]
id: UBERON:0000088
name: trophoblast
namespace: uberon
def: "The mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta." [ISBN:0-683-40008-8, MP:0005031]
comment: Aggregate of cells forming the outer layer of a blastocyst, which provide nutrients to the embryo and develop into a large part of the placenta. They are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg. [Wikipedia:Trophoblast]
subset: early_development
subset: pheno_slim
synonym: "massa cellularis externa" RELATED OMO:0003011 [Wikipedia:Trophoblast]
synonym: "trophoblast layer" EXACT [MP:0005031]
synonym: "trophoblastus" RELATED OMO:0003011 [Wikipedia:Trophoblast]
synonym: "trophoderm" RELATED [BTO:0001079]
xref: BTO:0001079
xref: CALOHA:TS-1070
xref: EV:0100120
xref: FMA:83029
xref: GAID:1152
xref: MESH:D014327
xref: NCIT:C93292
xref: SCTID:362839005
xref: UMLS:C0041178 {source="ncithesaurus:Trophoblast"}
xref: Wikipedia:Trophoblast
is_a: UBERON:0002050 ! embryonic structure
relationship: composed_primarily_of CL:0000351 ! trophoblast cell
relationship: develops_from UBERON:0004345 {source="MP-def", source="PMID:19829370"} ! trophectoderm
relationship: part_of UBERON:0000358 ! blastocyst
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI
property_value: UBPROP:0000001 "the mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta[MP]" xsd:string {date_retrieved="2012-08-23", external_class="MP:0005031", external_class_label="trophoblast layer", ontology="MP", source="ISBN:0-683-40008-8"}
property_value: UBPROP:0000007 "trophoblastic" xsd:string
property_value: UBPROP:0000011 "The postimplantation derivatives of the trophectoderm, which make up most of the fetal part of the placenta" xsd:string {source="PMID:19829370"}

[Term]
id: UBERON:0000091
name: bilaminar disc
namespace: uberon
def: "A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc." [MP:0003886]
subset: early_development
subset: pheno_slim
synonym: "bilaminar disk" RELATED [Wikipedia:Bilaminar_disc]
synonym: "bilaminary embryonic disc" EXACT []
synonym: "bilaminary germ disc" EXACT [ISBN:9780878932504]
synonym: "embryonic disc" BROAD [MP:0003886]
synonym: "embryonic shield" BROAD [MP:0003886]
synonym: "germinal disc" BROAD [MP:0003886]
synonym: "germinal disk" BROAD [MP:0003886]
xref: FMA:293863
xref: NCIT:C34112
xref: UMLS:C1283997 {source="ncithesaurus:Bilaminar_Embryonic_Disc"}
xref: Wikipedia:Bilaminar_disc
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0000087 {source="Wikipedia"} ! inner cell mass
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png" xsd:anyURI

[Term]
id: UBERON:0000092
name: post-embryonic stage
namespace: uberon
def: "Stage succeeding embryo, including mature structure." [https://orcid.org/0000-0002-6601-2165]
synonym: "post-hatching stage" NARROW []
synonym: "postembryonic" RELATED []
synonym: "postembryonic stage" EXACT []
xref: BilaDO:0000003
xref: OGES:000010
xref: OGES:000014
xref: OGES:000024
xref: WBls:0000022
xref: WBls:0000093
xref: WBls:0000103
is_a: UBERON:0000105 ! life cycle stage
relationship: preceded_by UBERON:0000068 ! embryo stage
relationship: simultaneous_with GO:0009791 ! post-embryonic development
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/344" xsd:anyURI
property_value: UBPROP:0000008 "In birds, the postnatal stage begins when the beak penetrates the shell (i.e., external pipping) (Brown et al. 1997)" xsd:string

[Term]
id: UBERON:0000094
name: membrane organ
namespace: uberon
def: "Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]." [FMA:7145]
synonym: "membrane" BROAD []
synonym: "membrane of organ" EXACT []
xref: FMA:7145
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000062 ! organ
relationship: composed_primarily_of UBERON:0011823 {source="FMA-def"} ! dense connective tissue
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-6601-2165
creation_date: 2009-07-30T05:19:13Z

[Term]
id: UBERON:0000095
name: cardiac neural crest
namespace: uberon
def: "Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]." [Wikipedia:Cardiac_neural_crest]
subset: vertebrate_core
synonym: "cardiac neural crest complex" RELATED [Wikipedia:Cardiac_neural_crest]
synonym: "complexus cristae neuralis cardiacus" RELATED [Wikipedia:Cardiac_neural_crest]
xref: TAO:0002173
xref: Wikipedia:Cardiac_neural_crest
xref: XAO:0004190
xref: ZFA:0001648
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
relationship: overlaps UBERON:0005428 {source="Wikipedia"} ! vagal neural crest
relationship: part_of UBERON:0002342 ! neural crest
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-6601-2165
property_value: UBPROP:0000001 "A subpopulation of the cephalic neural crest that emerges from the otic level to the anterior limit of somite 4. It migrates to the heart and is essential for the septation of the outflow track[DOI:10.1242/dev.091751]." xsd:string {source="DOI:10.1242/dev.091751"}
property_value: UBPROP:0000012 "ZFA treats this as a subtype of NC." xsd:string {external_ontology="ZFA"}
creation_date: 2009-07-30T07:57:38Z

[Term]
id: UBERON:0000101
name: lobe of lung
namespace: uberon
def: "A lung lobe is one of the rounded projections that compose the lung[GO]." [GOC:GO]
subset: pheno_slim
synonym: "lung lobe" EXACT []
synonym: "pulminory lobe" EXACT []
synonym: "pulmonary lobe" EXACT [FMA:7311]
xref: EMAPA:36281
xref: FMA:7311
xref: galen:LobeOfLung
xref: MA:0003098
xref: NCIT:C34021
xref: SCTID:245524004
xref: UMLS:C0225752 {source="ncithesaurus:Lung_Lobe"}
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0009912 {source="FMA"} ! anatomical lobe
relationship: contributes_to_morphology_of UBERON:0002048 ! lung
relationship: part_of UBERON:0002048 ! lung

[Term]
id: UBERON:0000102
name: lung vasculature
namespace: uberon
def: "The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]." [GOC:GO]
subset: pheno_slim
synonym: "lung vascular network" EXACT [OBOL:automatic]
synonym: "pulmonary vasculature" EXACT [FMA:73750]
synonym: "vascular network of lung" EXACT [OBOL:automatic]
synonym: "vasculature of lung" EXACT [OBOL:automatic]
xref: FMA:73750
is_a: UBERON:0002201 ! vasculature of trunk
is_a: UBERON:0006876 ! vasculature of organ
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0002048 ! lung
relationship: part_of UBERON:0002048 ! lung

[Term]
id: UBERON:0000104
name: life cycle
namespace: uberon
def: "An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism." [https://orcid.org/0000-0002-6601-2165]
subset: common_anatomy
subset: upper_level
synonym: "entire life cycle" EXACT []
synonym: "entire lifespan" EXACT []
synonym: "life" EXACT []
synonym: "lifespan" EXACT []
xref: FBdv:00000000
xref: HsapDv:0000001
xref: MmusDv:0000001
xref: ncithesaurus:Life
xref: OGES:000011
is_a: UBERON:0000000 ! processual entity
relationship: ends_with UBERON:0000071 ! death stage
relationship: has_part UBERON:0000105 ! life cycle stage
relationship: starts_with UBERON:0000106 {gci_relation="in_taxon", gci_filler="NCBITaxon:33208"} ! zygote stage
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/532" xsd:anyURI

[Term]
id: UBERON:0000105
name: life cycle stage
namespace: uberon
def: "A spatiotemporal region encompassing some part of the life cycle of an organism." [https://orcid.org/0000-0002-6601-2165]
subset: common_anatomy
subset: efo_slim
subset: upper_level
synonym: "developmental stage" NARROW []
synonym: "stage" NARROW []
xref: BILS:0000105
xref: EFO:0000399
xref: FBdv:00007012
xref: FMA:24120
xref: HsapDv:0000000
xref: MESH:D008018
xref: MmusDv:0000000
xref: ncithesaurus:Developmental_Stage
xref: OlatDv:0000010
xref: PdumDv:0000090
xref: WBls:0000002
xref: XAO:1000000
xref: ZFS:0000000
xref: ZFS:0100000
is_a: UBERON:0000000 ! processual entity
relationship: part_of UBERON:0000104 ! life cycle
property_value: editor_note "this class represents a proper part of the life cycle of an organism. The class 'life cycle' should not be placed here" xsd:string
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751
property_value: UBPROP:0000012 "the WBls class 'all stages' belongs here as it is the superclass of other WBls stages" xsd:string
property_value: UBPROP:0000012 "we map the ZFS unknown stage here as it is logically equivalent to saying *some* life cycle stage" xsd:string

[Term]
id: UBERON:0000106
name: zygote stage
namespace: uberon
def: "A stage at which the organism is a single cell produced by means of sexual reproduction." [Wikipedia:Zygote]
subset: efo_slim
synonym: "1-cell stage" EXACT []
synonym: "fertilized egg stage" EXACT [BTO:0000854]
synonym: "fertilized egg stage" RELATED []
synonym: "one cell stage" EXACT []
synonym: "one-cell stage" RELATED [VHOG:0000745]
synonym: "zygote" RELATED [VHOG:0000745]
synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote]
xref: BilaDO:0000005
xref: BILS:0000106
xref: EFO:0001322
xref: EHDAA:27
xref: FBdv:00005288
xref: IDOMAL:0000302 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C12601
xref: PdumDv:0000100
xref: VHOG:0000745
xref: Wikipedia:Zygote
xref: XAO:1000001
xref: ZFS:0000001
is_a: UBERON:0000105 ! life cycle stage
relationship: part_of UBERON:0000068 ! embryo stage
relationship: seeAlso EMAPA:16033
relationship: starts UBERON:0000104 ! life cycle
property_value: UBPROP:0000003 "As in all metazoans, eumetazoan development begins with a fertilized egg, or zygote.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000745", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.107", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000107
name: cleavage stage
namespace: uberon
def: "The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula." [GO:0040016, Wikipedia:Cleavage_(embryo)]
subset: efo_slim
xref: BilaDO:0000006
xref: BILS:0000107
xref: EFO:0001290
xref: FBdv:00000054
xref: MESH:D002970
xref: MmusDv:0000004
xref: OGES:000015
xref: OGES:000020
xref: PdumDv:0000200
xref: Wikipedia:Cleavage_(embryo)
xref: XAO:1000004
xref: ZFS:0000046
is_a: UBERON:0000105 ! life cycle stage
intersection_of: UBERON:0000105 ! life cycle stage
intersection_of: simultaneous_with GO:0040016 ! embryonic cleavage
relationship: immediately_preceded_by UBERON:0000106 ! zygote stage
relationship: part_of UBERON:0000068 ! embryo stage
relationship: simultaneous_with GO:0040016 ! embryonic cleavage

[Term]
id: UBERON:0000108
name: blastula stage
namespace: uberon
def: "An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula]
subset: efo_slim
xref: BilaDO:0000007
xref: BILS:0000108
xref: EFO:0001282
xref: HsapDv:0000006
xref: MmusDv:0000007
xref: OGES:000003
xref: OGES:000016
xref: OGES:000021
xref: WBls:0000005
xref: Wikipedia:Blastula
xref: XAO:1000003
xref: ZFS:0000045
is_a: UBERON:0000105 ! life cycle stage
relationship: part_of UBERON:0000068 ! embryo stage
relationship: preceded_by UBERON:0000107 ! cleavage stage
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI
property_value: editor_note "consider adding a preceding stage 'morula stage' as part of cleavage" xsd:string

[Term]
id: UBERON:0000109
name: gastrula stage
namespace: uberon
def: "A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GO:0007369]
subset: efo_slim
synonym: "blastocystis trilaminaris stage" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "trilaminar blastocyst stage" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "trilaminar blastoderm stage" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "trilaminar disk stage" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "trilaminar germ stage" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "trilaminar stage" RELATED [https://orcid.org/0000-0002-6601-2165]
xref: BilaDO:0000008
xref: BILS:0000109
xref: EFO:0001296
xref: FBdv:00005317
xref: HsapDv:0000010
xref: MmusDv:0000013
xref: OGES:000004
xref: OGES:000019
xref: WBls:0000010
xref: XAO:1000005
xref: ZFS:0000047
is_a: UBERON:0000105 ! life cycle stage
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000068 ! embryo stage
relationship: preceded_by UBERON:0000108 {source="BILS"} ! blastula stage
relationship: simultaneous_with GO:0007369 ! gastrulation

[Term]
id: UBERON:0000110
name: neurula stage
namespace: uberon
def: "Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GO:0001841]
xref: BilaDO:0000009
xref: BILS:0000110
xref: HsapDv:0000012
xref: MmusDv:0000017
xref: XAO:1000006
is_a: UBERON:0000105 ! life cycle stage
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000068 ! embryo stage
relationship: preceded_by UBERON:0000109 ! gastrula stage
relationship: simultaneous_with GO:0001841 ! neural tube formation
property_value: RO:0002174 NCBITaxon:7955
property_value: seeAlso "https://github.com/obophenotype/developmental-stage-ontologies/issues/84" xsd:anyURI
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/343" xsd:anyURI
property_value: UBPROP:0000008 "In zebrafish, the times of neurulation and segmentation overlap so extensively there is no distinct neurula period of development, such as occurs largely before segmentation in amphibian embryos." xsd:string

[Term]
id: UBERON:0000111
name: organogenesis stage
namespace: uberon
def: "A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism." [Wikipedia:Organogenesis]
synonym: "segmentation stage" RELATED []
xref: BilaDO:0000010
xref: BILS:0000111
xref: HsapDv:0000015
xref: MmusDv:0000018
xref: OGES:000005
xref: OGES:000032
xref: Wikipedia:Organogenesis
is_a: UBERON:0000105 ! life cycle stage
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000068 ! embryo stage
relationship: preceded_by UBERON:0000110 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! neurula stage
relationship: simultaneous_with GO:0048513 ! animal organ development
property_value: seeAlso "https://github.com/obophenotype/developmental-stage-ontologies/issues/84" xsd:anyURI
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/533" xsd:anyURI

[Term]
id: UBERON:0000112
name: sexually immature stage
namespace: uberon
subset: efo_slim
synonym: "immature stage" EXACT [VHOG:FB]
synonym: "juvenile stage" NARROW [XAO:1000010]
synonym: "subadult stage" RELATED [http://eol.org/schema/terms/subadult]
xref: BILS:0000112
xref: BTO:0002168
xref: EFO:0001300
xref: EV:0300051
xref: MmusDv:0000043
xref: OGES:000009
xref: XAO:1000010
xref: XtroDO:0000083
xref: ZFS:0000051
is_a: UBERON:0000105 ! life cycle stage
relationship: part_of UBERON:0000066 ! fully formed stage
relationship: preceded_by UBERON:0000069 {gci_relation="part_of", gci_filler="NCBITaxon:7955", source="ZFS"} ! larval stage
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/427" xsd:anyURI
property_value: UBPROP:0000001 "The stage of being a sexually immature adult animal[XAO:1000010]." xsd:string {source="XAO:1000010"}
property_value: UBPROP:0000008 "In mammals this would include infant (nourishment from lactation) and juvenile (prepubertal no longer dependent on mother)" xsd:string

[Term]
id: UBERON:0000113
name: post-juvenile adult stage
namespace: uberon
def: "The stage of being a sexually mature adult animal." [https://orcid.org/0000-0002-6601-2165]
synonym: "adult stage" BROAD []
xref: BILS:0000113
xref: EV:0300064
xref: EV:0300070
xref: MIAA:0000403
xref: MmusDv:0000110
xref: OGES:000026
xref: OGES:000027
xref: XAO:1000093
xref: ZFS:0000044
is_a: UBERON:0000105 ! life cycle stage
relationship: part_of UBERON:0000066 ! fully formed stage
relationship: preceded_by UBERON:0000112 ! sexually immature stage
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/345" xsd:anyURI
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/499" xsd:anyURI

[Term]
id: UBERON:0000114
name: lung connective tissue
namespace: uberon
def: "The connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin." [ISBN:0-683-40008-8, MGI:anna, MP:0002276, PMID:14635660]
subset: human_reference_atlas
subset: pheno_slim
synonym: "connective tissue of lung" EXACT [OBOL:automatic]
synonym: "lung interstitial tissue" RELATED [MA:0001782]
synonym: "lung interstitium" RELATED []
synonym: "pulmonary connective tissue" RELATED [EMAPA:35521]
synonym: "pulmonary interstitial tissue" RELATED []
synonym: "pulmonary interstitium" EXACT [FMA:27533]
xref: EMAPA:35521
xref: FMA:27533
xref: MA:0001782
xref: SCTID:201609008
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0003580 ! lower respiratory tract connective tissue
is_a: UBERON:0003837 ! thoracic segment connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0002048 ! lung
relationship: contributes_to_morphology_of UBERON:0002048 ! lung
relationship: develops_from UBERON:0004883 ! lung mesenchyme
relationship: part_of UBERON:0002048 ! lung
relationship: transformation_of UBERON:0004883 ! lung mesenchyme
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000009 "it functions in the mechanical behavior of the lung, and forms a barrier to regulate the flow of plasma constituents from the capillaries to the airway and alveolar spaces" xsd:string

[Term]
id: UBERON:0000115
name: lung epithelium
namespace: uberon
def: "The epithelial layer of the lung." [MP:0006382]
subset: pheno_slim
synonym: "epithelial tissue of lung" EXACT [OBOL:automatic]
synonym: "epithelium of lung" EXACT [OBOL:automatic]
synonym: "lung epithelial tissue" EXACT [OBOL:automatic]
synonym: "pulmonary epithelium" RELATED [BTO:0001653]
xref: BTO:0001653
xref: EMAPA:32860
xref: MA:0001783
is_a: UBERON:0004815 ! lower respiratory tract epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0002048 ! lung
relationship: contributes_to_morphology_of UBERON:0002048 ! lung
relationship: develops_from UBERON:0001041 ! foregut
relationship: part_of UBERON:0002048 ! lung
property_value: UBPROP:0000008 "A pseudostratified epithelium, containing basal cells, stem cells of the airway, submucosal glands and cartilage rings, is limited to the trachea and large lobar airways in the mouse (Morrisey and Hogan, 2010). This more complex epithelium extends to terminal bronchioles in the human[DOI:10.1242/dev.115469]" xsd:string

[Term]
id: UBERON:0000117
name: respiratory tube
namespace: uberon
def: "A tube in the respiratory system. Examples: bronchus, bronchiole, trachea." [GO:0030323, http://orcid.org/0000-0002-6601-2165]
synonym: "airway" RELATED []
synonym: "respiratory conducting tube" NARROW [MP:0004391]
synonym: "segment of tracheobronchial tree" EXACT [FMA:12224]
synonym: "segment of tracheobronchial tree" NARROW [FMA:12224]
synonym: "tracheobronchial tree segment" NARROW [FMA:12224]
xref: EMAPA:37946 {source="MA:th"}
xref: FMA:12224
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000025 ! tube
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000025 ! tube
intersection_of: part_of UBERON:0000065 ! respiratory tract
relationship: has_part UBERON:0000483 ! epithelium
relationship: part_of UBERON:0000065 ! respiratory tract
property_value: UBPROP:0000012 "in GO lung development is part of respiratory tube development. This can lead to inconsistencies with other ontologies, e.g. VT. The GO structure may be better represented by a tree of tubes (see the FMA class)" xsd:string {external_ontology="GO"}

[Term]
id: UBERON:0000118
name: lung bud
namespace: uberon
def: "Structure derived from foregut that becomes a lung[GO]." [GO:0060431, Wikipedia:Respiratory_bud]
subset: pheno_slim
synonym: "gemma pulmonalis" RELATED OMO:0003011 [Wikipedia:Lung_buds]
synonym: "gemma respiratoria" RELATED OMO:0003011 [Wikipedia:Lung_buds]
synonym: "lung bud" RELATED OMO:0003004 []
synonym: "primary lung bud" RELATED [GO:0060572]
synonym: "respiratory diverticulum" RELATED [Wikipedia:Lung_buds]
xref: BTO:0001643
xref: EHDAA2:0004089
xref: NCIT:C34260
xref: NCIT:C34282
xref: SCTID:361427007
xref: UMLS:C1514420 {source="ncithesaurus:Primary_Bronchial_Bud"}
xref: UMLS:C1514897 {source="ncithesaurus:Respiratory_Diverticulum"}
xref: Wikipedia:Respiratory_bud
is_a: UBERON:0005153 {source="GO:0060441"} ! epithelial bud
is_a: UBERON:0005911 ! endo-epithelium
relationship: adjacent_to UBERON:0004872 ! splanchnic layer of lateral plate mesoderm
relationship: develops_from UBERON:0005597 ! lung primordium
relationship: develops_from UBERON:0008947 {source="EHDAA2"} ! respiratory primordium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/71/Gray948.png" xsd:anyURI
property_value: editor_note "clarify successors - include bronchi?" xsd:string

[Term]
id: UBERON:0000122
name: neuron projection bundle
namespace: uberon
alt_id: UBERON:0005163
def: "A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses." [CARO:0001001, FBbt:00005099, FBC:DOS]
synonym: "funiculus" EXACT []
synonym: "nerve fiber bundle" EXACT [FBbt:00005099]
synonym: "neural fiber bundle" EXACT []
xref: CARO:0001001
xref: FBbt:00005099 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: NLX:147821
is_a: UBERON:0005162 ! multi cell part structure
relationship: has_part GO:0043005 ! neuron projection
relationship: part_of UBERON:0001016 ! nervous system

[Term]
id: UBERON:0000125
name: neural nucleus
namespace: uberon
def: "A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO)." [NLX:28443]
subset: cumbo
synonym: "nervous system nucleus" EXACT []
synonym: "neuraxis nucleus" EXACT [FMA:83686]
synonym: "neuronal nucleus" EXACT [AEO:0000136]
synonym: "nucleus" BROAD []
synonym: "nucleus of CNS" EXACT [NLX:28443]
synonym: "nucleus of neuraxis" RELATED []
xref: AEO:0000136
xref: FMA:83686
xref: NCIT:C13197
xref: NLX:28443
xref: Wikipedia:Nucleus_(neuroanatomy)
is_a: UBERON:0011215 ! central nervous system cell part cluster
relationship: composed_primarily_of UBERON:0002020 ! gray matter
relationship: only_in_taxon NCBITaxon:7711 {notes="we limit this structure by definition to chordate and vertebrate nervous systems"} ! Chordata
property_value: UBPROP:0000001 "Anatomical structure consisting of a discrete aggregate of neuronal soma[GO][GO_REF:0000021]." xsd:string {source="GO_REF:0000021"}
property_value: UBPROP:0000012 "Proposed CUMBO def from MM: A subcortical part of the nervous system consisting of a relatively compact group of cells that is distinguishable histologically that share a commonality of cytoarchitecture, chemoarchitecturel and connectivity. (comments: I put in 'subcortical' because I don't think we consider either the cerebellar cortex or cerebral cortex to be nuclei. Some people distinguish between a nucleus and a laminar structure (see Wikipedia definition). However, there are structures identified as nuclei that are laminar, e.g., lateral geniculate nucleus, although they are not laminated in all species. Also, I put in 'relatively compact' and 'distiguishable by histology' because we have groups of cells, e.g., cholinergic cell groups, doparminergic cell groups that are related on the 3 criteria but which we don't tend to consider nuclei because they don't occupy an easily defined territory. But all is open to debate." xsd:string

[Term]
id: UBERON:0000126
name: cranial nerve nucleus
namespace: uberon
def: "Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves." [NLX:28532]
synonym: "cranial neural nucleus" EXACT [FMA:54501]
synonym: "nucleus nervi cranialis" RELATED OMO:0003011 [Wikipedia:Cranial_nerve_nucleus]
synonym: "nucleus of cranial nerve" EXACT []
xref: EMAPA:37066 {source="MA:th"}
xref: FMA:54501
xref: NLX:28532
xref: SCTID:280160003
xref: Wikipedia:Cranial_nerve_nucleus
is_a: UBERON:0002308 ! nucleus of brain
intersection_of: UBERON:0002308 ! nucleus of brain
intersection_of: extends_fibers_into UBERON:0001785 ! cranial nerve
relationship: extends_fibers_into UBERON:0001785 ! cranial nerve
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png" xsd:anyURI

[Term]
id: UBERON:0000153
name: anterior region of body
namespace: uberon
is_a: UBERON:0000475 ! organism subdivision
disjoint_from: UBERON:0000154 {source="lexical"} ! posterior region of body
relationship: anterior_to UBERON:0000154 ! posterior region of body
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria

[Term]
id: UBERON:0000154
name: posterior region of body
namespace: uberon
is_a: UBERON:0000475 ! organism subdivision
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria

[Term]
id: UBERON:0000158
name: membranous layer
namespace: uberon
synonym: "membrane" BROAD []
synonym: "membranous organ component" EXACT [FMA:82500]
xref: FMA:30322
xref: FMA:82500
xref: MESH:D008566
xref: NCIT:C12749
is_a: UBERON:0004923 ! organ component layer
relationship: bounding_layer_of UBERON:0000064 ! organ part
property_value: UBPROP:0000001 "A thin sheet or layer of pliable tissue, serving as a covering or envelope of a part, as the lining of a cavity, as a partition or septum, or to connect two structures." xsd:string {source="ncithesaurus:Membrane"}

[Term]
id: UBERON:0000159
name: anal canal
namespace: uberon
def: "The terminal part of the large intestine, continuous proximally with the rectum and distally terminates with the anus." [Wikipedia:Anal_canal]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "anal canal" EXACT []
synonym: "anal canal viewed anatomically" EXACT []
synonym: "anal pad" RELATED []
synonym: "anatomical anal canal" EXACT []
synonym: "anus" RELATED []
synonym: "canalis analis" RELATED OMO:0003011 [BTO:0001978, Wikipedia:Anal_canal]
synonym: "cloaca" RELATED []
synonym: "cloacal chamber" RELATED []
synonym: "mesenteron" RELATED []
synonym: "pars analis recti" RELATED [BTO:0001978]
xref: BTO:0001978
xref: CALOHA:TS-2160
xref: EMAPA:18256
xref: FMA:15703
xref: galen:AnalCanal
xref: MA:0000330
xref: MESH:D001003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C12375
xref: SCTID:245438008
xref: UMLS:C0227411 {source="ncithesaurus:Anal_Canal"}
xref: Wikipedia:Anal_canal
is_a: UBERON:0004111 ! anatomical conduit
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: channel_for UBERON:0001988 ! feces
relationship: continuous_with UBERON:0001052 ! rectum
relationship: continuous_with UBERON:0001245 ! anus
relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! embryonic skin basal layer
relationship: part_of UBERON:0000059 ! large intestine
relationship: part_of UBERON:0001353 ! anal region
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/0/01/Gray1078.png" xsd:anyURI
property_value: editor_note "requires alignment with EHDAA2 and complete developmental relationships" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000160
name: intestine
namespace: uberon
def: "Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine." [GOC:GO, Wikipedia:Intestine]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "bowel" EXACT []
synonym: "intestinal tract" RELATED []
xref: AAO:0000246
xref: ANISEED:1235303
xref: BSA:0000093
xref: BTO:0000648
xref: CALOHA:TS-0490
xref: EFO:0000834
xref: EMAPA:32874
xref: EV:0100071
xref: FMA:7199
xref: GAID:295
xref: galen:Intestine
xref: MA:0000328
xref: MA:0001524
xref: MESH:D007422
xref: MIAA:0000043
xref: NCIT:C12736
xref: SCTID:256876008
xref: TAO:0001338
xref: UMLS:C0021853 {source="ncithesaurus:Intestine"}
xref: VHOG:0000056
xref: WBbt:0005772
xref: Wikipedia:Intestine
xref: XAO:0000129
xref: ZFA:0001338
is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract
relationship: contributes_to_morphology_of UBERON:0001007 ! digestive system
relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system
property_value: editor_note "This class is probably too inclusive" xsd:string
property_value: UBPROP:0000001 "Portion of the alimentary canal bounded anteriorly by the pyloric sphincter and posteriorly by the cloacal sphincter.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000246", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "The tract of the alimentary canal. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000056", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "intestinal" xsd:string
property_value: UBPROP:0000008 "In zebrafish, No stomach, small intestine, or large intestine can be distinguished. However, differences can be found in the morphology of the mucosa columnar epithelial cells and the number of goblet cells, suggesting functional differentiation. The intestine has numerous folds that become progressively shorter in a rostral-to-caudal direction. Proportionally, these folds are significantly larger than the finger-like intestinal villi of mammals and other amniotes (Wallace et al. 2005). Columnar-shaped absorptive enterocytes are the most numerous in the zebrafish intestinal epithelium. Goblet cells are the second most populous epithelial cell type." xsd:string

[Term]
id: UBERON:0000161
name: orifice
namespace: uberon
def: "Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]." [FMA:3724]
synonym: "anatomical orifice" EXACT [FMA:3724]
synonym: "anatomical ostium" BROAD [FMA:3724]
synonym: "hilum" NARROW []
synonym: "ostium" BROAD []
xref: FMA:3724
xref: SCTID:91837002
is_a: UBERON:0004111 ! anatomical conduit
property_value: UBPROP:0000012 "in FMA, this is an anatomical conduit *space*, rather than anatomical conduit" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0000162
name: cloaca
namespace: uberon
def: "Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures." [ISBN:0073040584, Wikipedia:Cloaca]
synonym: "cloacal chamber" RELATED [AAO:0000095]
synonym: "vent" RELATED [XAO:0000244]
xref: AAO:0000095
xref: GAID:1206
xref: MESH:D002988
xref: NCIT:C34127
xref: SCTID:362857006
xref: SCTID:370631000
xref: UMLS:C0008987 {source="ncithesaurus:Cloaca"}
xref: VHOG:0001186
xref: Wikipedia:Cloaca
xref: XAO:0000244
xref: ZFA:0005781
is_a: UBERON:0013522 ! subdivision of tube
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0001555 {source="ZFA"} ! digestive tract
relationship: part_of UBERON:0004122 {source="AAO"} ! genitourinary system
property_value: editor_note "adding df link to embryonic cloaca leads to a cycle in uberon-simple, as cloaca is a suberclass of embryonic cloaca" xsd:string
property_value: RO:0002175 NCBITaxon:9369 {notes="most adult placentals have no trace of a cloaca. However, the tenrecs and golden moles, small placental mammals native to Africa, retain a cloaca as adults."}
property_value: UBPROP:0000001 "A common passage for fecal, urinary, and reproductive discharge in most lower vertebrates as well as the terminal end of the hindgut before division into rectum, bladder, and genital primordia in mammalian embryos. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001186", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/cloaca"}
property_value: UBPROP:0000001 "Anatomical structure which is the common receptacle for the alimentary canal, Wolffian ducts, oviducts, and the bladder.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000095", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "A cloaca is apparently a primitive vertebrate feature because it occurs in most primitive gnathostomes and persists in the embryos of almost all vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001186", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.572", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "cloacal" xsd:string
property_value: UBPROP:0000008 "Human beings only have an embryonic cloaca, which is split up into separate tracts during the development of the urinary and reproductive organs" xsd:string
property_value: UBPROP:0000011 "hindgut endoderm and proctodeal ectoderm." xsd:string {source="WP"}

[Term]
id: UBERON:0000163
name: embryonic cloaca
namespace: uberon
def: "Endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]." [MP:0010115, Wikipedia:Cloaca_(embryology)]
subset: pheno_slim
synonym: "cloaca" RELATED SENSU []
xref: EHDAA2:0000256
xref: EHDAA:4895
xref: EMAPA:27573
xref: Wikipedia:Cloaca_(embryology)
is_a: UBERON:0000162 ! cloaca
relationship: has_developmental_contribution_from UBERON:0003064 ! intermediate mesoderm
relationship: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0001008 {source="EHDAA2"} ! renal system
relationship: part_of UBERON:0012361 {source="EHDAA2"} ! internal anal region
property_value: curator_notes "this class represents the embryonic form of the cloaca, as found in both mammals and non-mammals." xsd:string

[Term]
id: UBERON:0000164
name: primitive urogenital sinus
namespace: uberon
def: "The ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females." [ISBN:0-683-40008-8, MP:0010116]
subset: pheno_slim
synonym: "fetal UGS" EXACT [PMID:18977204]
synonym: "sinus urogenitalis" EXACT OMO:0003011 []
synonym: "UGS" EXACT [MP:0010116]
synonym: "urogenital sinus" BROAD [MP:0010116]
xref: EHDAA2:0004060
xref: EHDAA:5029
xref: EHDAA:5919
xref: EMAPA:17379
xref: NCIT:C34322
xref: SCTID:50961009
xref: UMLS:C0231057 {source="ncithesaurus:Urogenital_Sinus"}
xref: VHOG:0000414
xref: Wikipedia:Definitive_urogenital_sinus
is_a: UBERON:0002050 ! embryonic structure
relationship: contributes_to_morphology_of UBERON:0000163 ! embryonic cloaca
relationship: develops_from UBERON:0003064 ! intermediate mesoderm
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0000163 {source="MP-def"} ! embryonic cloaca
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png" xsd:anyURI
property_value: UBPROP:0000001 "The ventral part of the cloaca after its separation from the rectum, giving rise to the lower part of the bladder in both sexes, to the prostatic portion of the male urethra, and to the urethra and vestibule in the female. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000414", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/urogenital+sinus"}
property_value: UBPROP:0000003 "In mammals the lowly monotremes still have a cloaca. Higher types have done away with this structure and have a separate anal outlet for the rectum. The monotreme cloaca shows the initiation of this subdivision. The cloaca has such includes only the distal part, roughly comparable to the proctodeum. The more proximal part is divided into (1) a large dorsal passage into which the intestine opens, the coprodeum, and (2) a ventral portion, the urodeum with which the bladder connects. (...) the development of the placental mammals recapitulates in many respects the phylogenetic story. In the sexually indifferent stage of placental mammal there is a cloaca. While the indifferent stage still persists, a septum develops, and extends out to the closing membrane. This divides the cloaca into two chambers: a coprodeum continuous with the gut above, and a urodeum or urogenital sinus below.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000414", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970)p.388-89 and Figure 300", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000013 "the term 'urogenital sinus' may refer to the primitive urogenital sinus present as a transient developmental structure in most mammals or it may refer to a condition in which an unseptated cloaca persists in animals longer than normal" xsd:string {source="MP"}

[Term]
id: UBERON:0000165
name: mouth
namespace: uberon
def: "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract, Wikipedia:Mouth]
subset: efo_slim
subset: major_organ
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "adult mouth" NARROW []
synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth]
synonym: "cavitas oris" RELATED [BTO:0001090]
synonym: "cavum oris" RELATED [BTO:0001090]
synonym: "mouth cavity" RELATED [BTO:0001090]
synonym: "oral region" RELATED [EHDAA2:0001326]
synonym: "oral vestibule" RELATED [BTO:0001090]
synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA]
synonym: "rima oris" RELATED [BTO:0001090]
synonym: "stoma" RELATED []
synonym: "stomatodaeum" RELATED [VHOG:0000812]
synonym: "trophic apparatus" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "vestibule of mouth" RELATED [BTO:0001090]
synonym: "vestibulum oris" RELATED [BTO:0001090]
xref: AAO:0010355
xref: BTO:0001090
xref: BTO:0004698
xref: CALOHA:TS-1315
xref: EFO:0000825
xref: EHDAA2:0001326
xref: EHDAA:542
xref: EMAPA:16262
xref: FBbt:00003126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:49184
xref: GAID:75
xref: galen:Mouth
xref: http://purl.obolibrary.org/obo/uberon/images/lamprey_sucker_rosava_3238889218.jpg
xref: MA:0000341
xref: MA:0002474
xref: MAT:0000038
xref: MESH:D009055
xref: MIAA:0000038
xref: SCTID:21082005
xref: TADS:0000040
xref: TAO:0000547
xref: TAO:0000590
xref: TGMA:0000131
xref: VHOG:0000280
xref: VHOG:0000812
xref: Wikipedia:Mouth
xref: XAO:0003029
xref: ZFA:0000547
xref: ZFA:0000590
is_a: UBERON:0004921 {notes="the mouth contains structures such as jaw skeleton that may not strictly be considered tract parts"} ! subdivision of digestive tract
intersection_of: UBERON:0004921 ! subdivision of digestive tract
intersection_of: proximalmost_part_of UBERON:0001555 ! digestive tract
relationship: develops_from UBERON:0035804 ! future mouth
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: proximalmost_part_of UBERON:0001555 ! digestive tract
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/0/06/Mouth_illustration-Otis_Archives.jpg" xsd:anyURI
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/661" xsd:anyURI
property_value: UBPROP:0000001 "Cavity in which food is initially ingested and generally contains teeth, tongue and glands.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010355", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "Molecular and developmental cell lineage data suggest that the acoel mouth opening is homologous to the mouth of protostomes and deuterostomes and that the last common ancestor of the Bilateria (the 'urbilaterian') had only this single digestive opening.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000812", ontology="VHOG", source="DOI:10.1038/nature07309 Hejnol A, Martindale MQ, Acoel development indicates the independent evolution of the bilaterian mouth and anus. Nature (2008)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "oral" xsd:string
property_value: UBPROP:0000011 "some AOs place this as developing from the stomodeum but we weaken this to developmental contribution, as the mouth includes non-ectodermal derivatives" xsd:string
property_value: UBPROP:0000012 "in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0000166
name: oral opening
namespace: uberon
def: "The orifice that connects the mouth to the exterior of the body." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract]
subset: uberon_slim
subset: vertebrate_core
synonym: "mouth" RELATED INCONSISTENT []
synonym: "oral fissure" EXACT [FMA:59806]
synonym: "oral orifice" EXACT [FMA:59806]
synonym: "oral part of face" RELATED []
xref: FMA:59806
is_a: UBERON:0000161 {source="FMA"} ! orifice
relationship: overlaps UBERON:0001004 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! respiratory system
relationship: part_of UBERON:0000165 ! mouth
property_value: UBPROP:0000003 "(...) mouth development is very similar in protostomes and 'basal' deuterostomes, whereas the chordate mouth seems to develop at a new position. Recent data for echinoderms and hemichordates further suggest that this change in mouth position may result from change in the influence of a conserved ectodermal patterning system on mouth development. It has been suggested that the mouths of vertebrates and urochordates may constitute a 'new' mouth.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000280", ontology="VHOG", source="DOI:10.1016/j.semcdb.2007.06.002 Christiaen L, Jaszczyszyn Y, Kerfant M, Kanob S, Thermes V, Joly JS, Evolutionary modification of mouth position in deuterostomes. Seminars in Cell and Developmental Biology (2007)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000167
name: oral cavity
namespace: uberon
def: "Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present)." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract, https://orcid.org/0000-0002-6601-2165, ISBN:0073040584]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "bucca" RELATED []
synonym: "buccal cavity" EXACT [FMA:20292, ISBN:0073040584]
synonym: "cavity of mouth" EXACT []
xref: AAO:0000053
xref: AAO:0000960
xref: BSA:0000107
xref: CALOHA:TS-1315
xref: EFO:0001975
xref: EHDAA2:0001324
xref: EHDAA:6970
xref: EMAPA:17411
xref: EMAPA:18399
xref: EV:0100057
xref: FMA:20292
xref: HAO:0000669
xref: MESH:D009055 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: NCIT:C12421
xref: SCTID:181220002
xref: TAO:0001027
xref: TGMA:0000102
xref: UMLS:C0226896 {source="ncithesaurus:Oral_Cavity"}
xref: VHOG:0000188
xref: WBbt:0005255
xref: XAO:0000126
xref: ZFA:0001027
is_a: UBERON:0002553 ! anatomical cavity
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000165 ! mouth
relationship: contributes_to_morphology_of UBERON:0000165 ! mouth
relationship: luminal_space_of UBERON:0000165 ! mouth
relationship: part_of UBERON:0000165 ! mouth
property_value: UBPROP:0000001 "Anatomical cavity bounded anteriorly by the mouth and posteriorly by the derivatives of the branchial arches.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000960", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "The cavity of the mouth, bounded by the jaw bones and associated structures (muscles and mucosa). [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000188", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/oral+cavity"}
property_value: UBPROP:0000003 "Echinoderms, hemichordates, and chordates are called deuterostomes because the mouth arises not from the blastopore but from a second invagination at the anterior end of the larva that pushes in to connect with the archenteron.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000188", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.32", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000168
name: proximal-distal subdivision of colon
namespace: uberon
def: "A section dividing a colon along a proximal-distal axis." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
synonym: "segment of colon" RELATED [FMA:222905]
xref: FMA:222905
is_a: UBERON:0004921 {order="4", source="cjm"} ! subdivision of digestive tract
intersection_of: UBERON:0013522 ! subdivision of tube
intersection_of: subdivision_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon
relationship: subdivision_of UBERON:0001155 ! colon

[Term]
id: UBERON:0000170
name: pair of lungs
namespace: uberon
def: "The pair of anatomical structures comprised of a left lung and right lung." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
synonym: "lungs" EXACT []
synonym: "lungs pair" EXACT []
synonym: "pulmones" EXACT OMO:0003011 [FMA:68877, FMA:TA]
synonym: "set of lungs" EXACT []
xref: FMA:68877
is_a: UBERON:0034925 ! anatomical collection
intersection_of: UBERON:0034925 ! anatomical collection
intersection_of: has_member UBERON:0002167 ! right lung
intersection_of: has_member UBERON:0002168 ! left lung
relationship: has_member UBERON:0002167 ! right lung
relationship: has_member UBERON:0002167 {cardinality="1"} ! right lung
relationship: has_member UBERON:0002168 ! left lung
relationship: has_member UBERON:0002168 {cardinality="1"} ! left lung
relationship: located_in UBERON:0002224 ! thoracic cavity
relationship: part_of UBERON:0001558 {source="FMA-abduced"} ! lower respiratory tract
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000171
name: respiration organ
namespace: uberon
def: "Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [GO:0007585]
subset: functional_classification
subset: organ_slim
synonym: "apparatus respiratorius organ" EXACT [OBOL:automatic]
synonym: "breathing organ" EXACT []
synonym: "gas exchange organ" RELATED []
synonym: "organ of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "organ of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory organ" EXACT []
synonym: "respiratory system organ" EXACT [OBOL:automatic]
xref: EMAPA:17607
xref: SCTID:272626006
xref: SPD:0000428
xref: TGMA:0001247
is_a: UBERON:0000062 ! organ
intersection_of: UBERON:0000062 ! organ
intersection_of: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system
relationship: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system
relationship: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0000174
name: excreta
namespace: uberon
alt_id: UBERON:0000324
alt_id: UBERON:0007550
def: "A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity." [GO:0007588, http://orcid.org/0000-0002-6601-2165]
synonym: "excreted substance" EXACT []
synonym: "excretion" RELATED [BTO:0000491]
synonym: "portion of excreted substance" EXACT [FMA:9674]
synonym: "waste substance" EXACT [AEO:0000184]
xref: AEO:0000184
xref: BTO:0000491
xref: EHDAA2_RETIRED:0003184
xref: ENVO:02000022
xref: FMA:9674
xref: galen:Excretion
is_a: UBERON:0000463 ! organism substance
intersection_of: UBERON:0000463 ! organism substance
intersection_of: output_of GO:0007588 ! excretion
relationship: output_of GO:0007588 ! excretion

[Term]
id: UBERON:0000178
name: blood
namespace: uberon
def: "A fluid that is composed of blood plasma and erythrocytes." [FMA:9670, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/9, Wikipedia:Blood]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "portion of blood" EXACT []
synonym: "vertebrate blood" EXACT []
synonym: "whole blood" RELATED [BTO:0000089]
xref: AAO:0000046
xref: BTO:0000089
xref: CALOHA:TS-0079
xref: EFO:0000296
xref: EHDAA2:0000176
xref: EHDAA:418
xref: EMAPA:16332
xref: ENVO:02000027
xref: EV:0100047
xref: FMA:9670
xref: GAID:965
xref: galen:Blood
xref: MA:0000059
xref: MESH:D001769
xref: MIAA:0000315
xref: NCIT:C12434
xref: TAO:0000007
xref: UMLS:C0005767 {source="ncithesaurus:Blood"}
xref: VHOG:0000224
xref: Wikipedia:Blood
xref: XAO:0000124
xref: ZFA:0000007
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000179 ! haemolymphatic fluid
relationship: develops_from UBERON:0006596 ! presumptive blood
relationship: has_part CL:0000232 {source="CL:tm"} ! erythrocyte
relationship: has_part UBERON:0001969 ! blood plasma
relationship: immediate_transformation_of UBERON:0006596 {source="Bgee:AN"} ! presumptive blood
relationship: located_in UBERON:0002049 {source="https://github.com/obophenotype/uberon/issues/1330"} ! vasculature
relationship: part_of UBERON:0002390 ! hematopoietic system
property_value: curator_notes "This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid." xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/tmeehan
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A complex mixture of cells suspended in a liquid matrix that delivers nutrients to cells and removes wastes. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000007", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Highly specialized circulating tissue consisting of several types of cells suspended in a fluid medium known as plasma.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000046", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000002 "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000046", ontology="AAO"}
property_value: UBPROP:0000003 "Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrates phyla. (...) There is now good reason to believe that, in vertebrates and invertebrates alike, blood cell lineages diverge from a common type of progenitor cell, the hemocytoblast.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000224", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.22.010605.093317 Hartenstein V, Blood cells and blood cell development in the animal kingdom. Annual review of cell and developmental biology (2006) ", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000179
name: haemolymphatic fluid
namespace: uberon
def: "Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs." [http://orcid.org/0000-0002-6601-2165]
synonym: "blood or blood analog" RELATED []
synonym: "circulating fluid" RELATED []
xref: CARO:0000081
is_a: UBERON:0006314 ! bodily fluid
intersection_of: UBERON:0000463 ! organism substance
intersection_of: part_of UBERON:0002193 ! hemolymphoid system
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0002193 ! hemolymphoid system
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-6601-2165
creation_date: 2009-04-08T04:38:19Z

[Term]
id: UBERON:0000209
name: tetrapod frontal bone
namespace: uberon
def: "The bone forming the forehead and roof of the eye orbit." [ISBN:0-683-40008-8, MP:0000107, PMID:7914451, Wikipedia:Frontal_bone]
subset: human_reference_atlas
subset: pheno_slim
synonym: "frontal" NARROW [AAO:0000206]
synonym: "frontal bone" NARROW SENSU [FMA:52734, MA:0001466]
synonym: "os frontal" NARROW SENSU [Wikipedia:Frontal_bone]
synonym: "os frontale" RELATED OMO:0003011 [Wikipedia:Frontal_bone]
xref: AAO:0000206
xref: EMAPA:19016
xref: FMA:52734
xref: GAID:226
xref: MA:0001466
xref: MESH:D005624
xref: NCIT:C32635
xref: SCTID:181793006
xref: UMLS:C0016732 {source="ncithesaurus:Frontal_Bone"}
xref: VHOG:0001324
xref: VSAO:0000208
xref: Wikipedia:Frontal_bone
is_a: UBERON:0002514 ! intramembranous bone
is_a: UBERON:0008907 ! dermal bone
is_a: UBERON:0010428 {source="FMA"} ! flat bone
is_a: UBERON:0011164 ! neurocranium bone
relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone
relationship: connected_to UBERON:0001679 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! ethmoid bone
relationship: overlaps UBERON:0001697 ! orbit of skull
relationship: part_of UBERON:0003113 {source="cjm"} ! dermatocranium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray136.png" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/5/5b/Frontal_bone.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "fused in humans, paired in other animals" xsd:string
property_value: UBPROP:0000011 "In the mouse the parietal originates from cephalic paraxial mesoderm (Jiang 2000; Morriss-Kay 2001), whereas in the chicken it is traced back to either mesodermal (Noden 1978) or neural crest (Couly 1992, 1993)." xsd:string

[Term]
id: UBERON:0000211
name: ligament
namespace: uberon
def: "Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000073]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "ligament organ" EXACT [FMA:21496]
xref: CALOHA:TS-2145
xref: EFO:0001966
xref: EMAPA:35493
xref: FMA:21496
xref: FMA:30319
xref: galen:Ligament
xref: MA:0000113
xref: MESH:D008022
xref: NCIT:C13046
xref: SCTID:182358004
xref: TAO:0001682
xref: UMLS:C0023685 {source="ncithesaurus:Ligament"}
xref: VHOG:0001272
xref: Wikipedia:Ligament
xref: XAO:0004031
xref: ZFA:0001675
is_a: UBERON:0000062 ! organ
relationship: has_part UBERON:0002384 ! connective tissue
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/9/9a/Knee_diagram.svg" xsd:anyURI
property_value: UBPROP:0000001 "Nonparenchymatous organ that primarily consists of dense connective tissue aggregated into fasciculi by connective tissue. Examples: sutural ligament, radiate sternocostal ligament, ligament of liver, ovarian ligament[FMA][FMA:21496]." xsd:string {source="FMA:21496"}
property_value: UBPROP:0000001 "Portion of connective tissue that connects bone or cartilage.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001682", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000003 "Compared with their Ediacarian predecessor, Cambrian animals in general were characterized by their much stouter bodies. The stoutness of the body is likely due to the formation of ligaments and tendons, which in turn requires the crosslinking of collagen triple helices.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001272", ontology="VHOG", source="PMID:8710894 Ohno S, The notion of the Cambrian pananimalia genome. PNAS (1996)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "this groups both skeletal and non-skeletal ligaments. What is called a 'ligament' in many AOs is actually a skeletal ligament" xsd:string

[Term]
id: UBERON:0000219
name: vertebral foramen of atlas
namespace: uberon
synonym: "vertebral foramen of cervical vertebra 1" EXACT []
xref: FMA:24293
xref: SCTID:281228008
xref: Wikipedia:Atlas_(anatomy)#Vertebral_foramen
is_a: UBERON:0001131 ! vertebral foramen
is_a: UBERON:0005744 ! bone foramen
intersection_of: UBERON:0001131 ! vertebral foramen
intersection_of: part_of UBERON:0001092 ! vertebral bone 1
relationship: part_of UBERON:0001092 ! vertebral bone 1

[Term]
id: UBERON:0000220
name: atlanto-occipital joint
namespace: uberon
def: "The Atlanto-occipital joint (articulation between the atlas and the occipital bone) consists of a pair of condyloid joints. The atlanto-occipital joint is a synovial joint. The ligaments connecting the bones are: Two Articular capsules; Posterior atlantoöccipital membrane; Anterior atlantoöccipital membrane; Lateral atlantoöccipital." [Wikipedia:Atlanto-occipital_joint]
synonym: "articulatio atlanto-occipitalis" EXACT [FMA:24939]
synonym: "articulatio atlantooccipitalis" RELATED OMO:0003011 [Wikipedia:Atlanto-occipital_joint]
synonym: "atlanto occipital joint" EXACT []
synonym: "atlantooccipital joint" EXACT []
synonym: "craniovertebral joint" EXACT [FMA:24939]
synonym: "occipito atlantal joint" EXACT []
synonym: "occipito-atlantal joint" EXACT []
xref: FMA:24939
xref: MESH:D001269 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C32158
xref: ncithesaurus:Atlanto-occipital_Joint-Atlanto
xref: SCTID:361831006
xref: UMLS:C0004169 {source="ncithesaurus:Atlanto-occipital_Joint"}
xref: Wikipedia:Atlanto-occipital_joint
is_a: UBERON:0002217 ! synovial joint
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0002217 ! synovial joint
intersection_of: connects UBERON:0001092 ! vertebral bone 1
intersection_of: connects UBERON:0001676 ! occipital bone
relationship: connects UBERON:0001092 ! vertebral bone 1
relationship: connects UBERON:0001676 ! occipital bone
relationship: in_lateral_side_of UBERON:0006072 {source="FMA-abduced-lr"} ! cervical region of vertebral column
relationship: part_of UBERON:0006072 ! cervical region of vertebral column
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png" xsd:anyURI

[Term]
id: UBERON:0000304
name: tendon sheath
namespace: uberon
def: "A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath." [Wikipedia:Tendon_sheath]
synonym: "synovial tendon sheath" EXACT [FMA:45087]
synonym: "vagina tendinis" RELATED OMO:0003011 [Wikipedia:Tendon_sheath]
xref: BTO:0000051
xref: FMA:45087
xref: FMA:76715
xref: NCIT:C96299
xref: SCTID:361885006
xref: UMLS:C0224856 {source="ncithesaurus:Tendon_Sheath"}
xref: Wikipedia:Tendon_sheath
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: bounding_layer_of UBERON:0000043 ! tendon
relationship: bounding_layer_of UBERON:0000043 ! tendon
relationship: has_part UBERON:0011233 ! synovial membrane of synovial tendon sheath
relationship: has_part UBERON:0011234 ! fibrous membrane of synovial tendon sheath
relationship: part_of UBERON:0000043 ! tendon
property_value: editor_note "TODO - add layer relations. 'tendon sheath' GAT in FMA." xsd:string

[Term]
id: UBERON:0000307
name: blastula
namespace: uberon
alt_id: UBERON:0007011
def: "Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula]
subset: inconsistent_with_fma
synonym: "blastosphere" RELATED [Wikipedia:Blastula]
synonym: "blastula embryo" EXACT [BILA:0000059]
xref: BILA:0000059
xref: BTO:0000128
xref: GAID:1294
xref: MESH:D036703
xref: OGEM:000006
xref: Wikipedia:Blastula
is_a: UBERON:0000922 ! embryo
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: existence_starts_and_ends_during UBERON:0000108 ! blastula stage
relationship: develops_from UBERON:0007010 ! cleaving embryo
relationship: existence_starts_and_ends_during UBERON:0000108 ! blastula stage
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI
property_value: editor_note "TODO - check relationship with epiblast. Note in FMA this is not a subclass of embryo, but in uberon embryo is the whole organism from zygote onwards and thus includes the blastula" xsd:string

[Term]
id: UBERON:0000317
name: colonic mucosa
namespace: uberon
alt_id: UBERON:0003347
alt_id: UBERON:0004981
def: "Mucosa that is part of a colon. The mucosa of the colon is lined by a simple columnar epithelium with a thin brush border and numerous goblet cells." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: human_reference_atlas
synonym: "colon mucosa" EXACT [FMA:14984]
synonym: "colon mucous membrane" EXACT [OBOL:automatic]
synonym: "colonic mucosa" EXACT []
synonym: "colonic mucous membrane" EXACT [FMA:14984]
synonym: "large bowel mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of colon" EXACT [FMA:14984]
synonym: "mucosa of large bowel" EXACT [OBOL:automatic]
xref: BTO:0000271
xref: CALOHA:TS-0164
xref: EFO:0003038
xref: EMAPA:27375
xref: FMA:14984
xref: FMA:85388
xref: MA:0003194
xref: SCTID:362157008
is_a: UBERON:0001207 ! mucosa of large intestine
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000320
name: duodenal mucosa
namespace: uberon
alt_id: UBERON:0003348
def: "A mucosa that is part of a duodenum [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "doudenal mucosa" EXACT [FMA:14942]
synonym: "duodenal mucous membrane" EXACT [FMA:14942]
synonym: "duodenum mucosa" RELATED [BTO:0000367]
synonym: "mucosa of duodenum" EXACT [OBOL:automatic]
synonym: "mucous membrane of duodenum" EXACT [OBOL:automatic]
xref: BTO:0000367
xref: CALOHA:TS-0213
xref: EMAPA:27235
xref: FMA:14942
xref: MA:0003207
xref: SCTID:362146003
is_a: UBERON:0001204 ! mucosa of small intestine
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: part_of UBERON:0002114 ! duodenum
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000323
name: late embryo
namespace: uberon
def: "An embryo that is at the late embryonic stage; this stage covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching." [https://orcid.org/0000-0003-3308-6245]
subset: efo_slim
subset: pheno_slim
synonym: "embryo late growth stage" RELATED [BTO:0000449]
synonym: "embryo late stage" RELATED [BTO:0000449]
synonym: "fetus" NARROW [BTO:0000449]
xref: BTO:0000449
xref: CALOHA:TS-0360
xref: EFO:0001323
xref: FBbt:00005333 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:63919
xref: GAID:552
xref: MESH:D005333
xref: NCIT:C13235
xref: SCTID:83418008
xref: UMLS:C0015965 {source="ncithesaurus:Fetus"}
is_a: UBERON:0000922 ! embryo
intersection_of: UBERON:0000922 ! embryo
intersection_of: existence_starts_and_ends_during UBERON:0007220 ! late embryonic stage
relationship: existence_starts_and_ends_during UBERON:0007220 ! late embryonic stage
property_value: editor_note "TODO - check fetus/embryo. WP: An embryo is a multicellular diploid eukaryote in its earliest stage of development, from the time of first cell division until birth, hatching, or germination. In humans, it is called an embryo until about eight weeks after fertilization (i.e. ten weeks LMP), and from then it is instead called a fetus." xsd:string
property_value: UBPROP:0000001 "Fetal structure, which is a developmental form of a vertebrate animal at any given time point from 8 weeks of gestation to birth (or hatching). Examples: There is only one fetus[FMA:63919]." xsd:string {source="FMA:63919"}

[Term]
id: UBERON:0000325
name: gastric gland
namespace: uberon
def: "The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin." [MGI:anna]
subset: organ_slim
subset: pheno_slim
xref: BTO:0000503
xref: EMAPA:27181
xref: FMA:14919
is_a: UBERON:0002365 {source="cjm"} ! exocrine gland
is_a: UBERON:0003294 ! gland of foregut
relationship: part_of UBERON:0006924 {source="ISBN:0073040584"} ! stomach glandular epithelium

[Term]
id: UBERON:0000326
name: pancreatic juice
namespace: uberon
def: "Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach." [GO:0030157]
synonym: "pancreatic fluid" RELATED []
synonym: "pancreatic secretion" RELATED []
synonym: "succus pancreaticus" RELATED [BTO:0000504]
xref: BTO:0000504
xref: CALOHA:TS-2235
xref: FMA:62973
xref: GAID:1166
xref: MESH:D010189
is_a: UBERON:0000456 ! secretion of exocrine gland
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: produced_by UBERON:0001264 ! pancreas
relationship: produced_by UBERON:0001264 ! pancreas

[Term]
id: UBERON:0000328
name: gut wall
namespace: uberon
def: "The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity)." [http://orcid.org/0000-0002-6601-2165]
synonym: "digestive tract wall" EXACT []
synonym: "wall of alimentary tract" RELATED []
synonym: "wall of digestive tract" EXACT []
synonym: "wall of gut" EXACT [FMA:45653]
xref: BTO:0000547
xref: FMA:45653
is_a: UBERON:0000060 ! anatomical wall
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001555 ! digestive tract
relationship: part_of UBERON:0001555 ! digestive tract
property_value: curator_notes "We model the digestive tract as consisting of two parts: the wall and the lumen." xsd:string

[Term]
id: UBERON:0000332
name: yellow bone marrow
namespace: uberon
def: "Bone marrow in which the fat cells predominate in the meshes of the reticular network." [http://medical-dictionary.thefreedictionary.com/Yellow+Marrow]
synonym: "fat marrow" RELATED [BTO:0000635]
synonym: "medulla ossium flava" EXACT OMO:0003011 [BTO:0000635]
synonym: "yellow marrow" EXACT [BTO:0000635]
xref: BTO:0000635
xref: FMA:74596
xref: SCTID:328639002
xref: SCTID:5023006
is_a: UBERON:0002371 ! bone marrow
intersection_of: UBERON:0002371 ! bone marrow
intersection_of: composed_primarily_of CL:0000136 ! adipocyte
relationship: composed_primarily_of CL:0000136 ! adipocyte
relationship: part_of UBERON:0007195 ! stroma of bone marrow

[Term]
id: UBERON:0000333
name: intestinal gland
namespace: uberon
def: "A gland that is part of the intestinal mucosa. Examples include the intestinal crypts, duodenal gland[cjm]." [https://orcid.org/0000-0002-6601-2165]
subset: organ_slim
synonym: "bowel mucosa gland" EXACT [OBOL:automatic]
synonym: "bowel mucosa of organ gland" EXACT [OBOL:automatic]
synonym: "bowel mucous membrane gland" EXACT [OBOL:automatic]
synonym: "bowel organ mucosa gland" EXACT [OBOL:automatic]
synonym: "gland of bowel mucosa" EXACT [OBOL:automatic]
synonym: "gland of bowel mucosa of organ" EXACT [OBOL:automatic]
synonym: "gland of bowel mucous membrane" EXACT [OBOL:automatic]
synonym: "gland of bowel organ mucosa" EXACT [OBOL:automatic]
synonym: "gland of intestinal mucosa" EXACT [OBOL:automatic]
synonym: "gland of intestine mucosa" EXACT [OBOL:automatic]
synonym: "gland of intestine mucosa of organ" EXACT [OBOL:automatic]
synonym: "gland of intestine mucous membrane" EXACT [OBOL:automatic]
synonym: "gland of intestine organ mucosa" EXACT [OBOL:automatic]
synonym: "gland of mucosa of bowel" EXACT [OBOL:automatic]
synonym: "gland of mucosa of intestine" EXACT [OBOL:automatic]
synonym: "gland of mucosa of organ of bowel" EXACT [OBOL:automatic]
synonym: "gland of mucosa of organ of intestine" EXACT [OBOL:automatic]
synonym: "gland of mucous membrane of bowel" EXACT [OBOL:automatic]
synonym: "gland of mucous membrane of intestine" EXACT [OBOL:automatic]
synonym: "gland of organ mucosa of bowel" EXACT [OBOL:automatic]
synonym: "gland of organ mucosa of intestine" EXACT [OBOL:automatic]
synonym: "glandula intestinalis" EXACT [FMA:15052]
synonym: "glandulae intestinales" RELATED []
synonym: "intestinal mucosa gland" EXACT [OBOL:automatic]
synonym: "intestine mucosa gland" EXACT [OBOL:automatic]
synonym: "intestine mucosa of organ gland" EXACT [OBOL:automatic]
synonym: "intestine mucous membrane gland" EXACT [OBOL:automatic]
synonym: "intestine organ mucosa gland" EXACT [OBOL:automatic]
synonym: "mucosa of bowel gland" EXACT [OBOL:automatic]
synonym: "mucosa of intestine gland" EXACT [OBOL:automatic]
synonym: "mucosa of organ of bowel gland" EXACT [OBOL:automatic]
synonym: "mucosa of organ of intestine gland" EXACT [OBOL:automatic]
synonym: "mucous membrane of bowel gland" EXACT [OBOL:automatic]
synonym: "mucous membrane of intestine gland" EXACT [OBOL:automatic]
synonym: "organ mucosa of bowel gland" EXACT [OBOL:automatic]
synonym: "organ mucosa of intestine gland" EXACT [OBOL:automatic]
xref: BTO:0000640
xref: FMA:15052
xref: SCTID:266297002
is_a: UBERON:0003408 ! gland of digestive tract
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0001242 ! intestinal mucosa
relationship: part_of UBERON:0001242 ! intestinal mucosa
property_value: UBPROP:0000012 "Note that some sources treat 'intestinal gland' as synonymous with crypts" xsd:string

[Term]
id: UBERON:0000344
name: mucosa
namespace: uberon
def: "A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]." [Wikipedia:Mucous_membrane]
subset: pheno_slim
synonym: "mucosa of organ" EXACT [FMA:85355]
synonym: "mucosa of organ part" EXACT [FMA:85358]
synonym: "mucosal region" EXACT [FMA:85358]
synonym: "mucous membrane" EXACT [FMA:85355]
synonym: "organ mucosa" EXACT [FMA:85355]
synonym: "region of mucosa" RELATED [FMA:85358]
synonym: "tunica mucosa" RELATED OMO:0003011 [BTO:0000886, Wikipedia:Mucous_membrane]
xref: AEO:0000199
xref: BTO:0000886
xref: CALOHA:TS-2031
xref: EHDAA2_RETIRED:0003234
xref: EV:0100382
xref: FMA:85355
xref: FMA:85358
xref: GAID:297
xref: galen:Mucosa
xref: MESH:D009092
xref: NCIT:C13166
xref: SCTID:361693009
xref: UMLS:C0026724 {source="ncithesaurus:Mucosa"}
xref: Wikipedia:Mucous_membrane
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004923 ! organ component layer
relationship: has_part UBERON:0000483 ! epithelium
relationship: has_part UBERON:0002384 ! connective tissue
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI
property_value: RO:0002171 UBERON:0000009
property_value: UBPROP:0000007 "mucosal" xsd:string
property_value: UBPROP:0000012 "FMA has mucosa vs region of mucosa; these are subtypes of Mucosa: Mucosa of gallbladder, tongue, .... The following are subtypes of Region of mucosa: Mucosa of zone of stomach, trachea, bronchus, dorsum of tongue.... Depends on whether the covered area is an organ or organ component. Uberon does not regard organ vs organ component as crucial distinction and thus collapses these into a single class deliberately" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0000353
name: parenchyma
namespace: uberon
def: "Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues." [Wikipedia:Parenchyma]
xref: BTO:0000999 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: BTO:0001539 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: EHDAA:3015
xref: EHDAA:3905
xref: EHDAA:3999
xref: EHDAA:4005
xref: EHDAA:6899
xref: EHDAA:6903
xref: EHDAA:6994
xref: EHDAA:8086
xref: EHDAA:9182
xref: EHDAA:9190
xref: EHDAA:9196
xref: EHDAA:9202
xref: FMA:45732
xref: NCIT:C74601
xref: UMLS:C0933845 {source="ncithesaurus:Parenchyma"}
xref: Wikipedia:Parenchyma
is_a: UBERON:0000064 ! organ part
disjoint_from: UBERON:0003891 ! stroma
relationship: capable_of GO:0032501 ! multicellular organismal process
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: UBPROP:0000007 "parenchymal" xsd:string
property_value: UBPROP:0000011 "Early in development the mammalian embryo has three distinct layers: ectoderm (external layer), endoderm (internal layer) and in between those two layers the middle layer or mesoderm. The parenchyma of most organs is of ectodermal (brain, skin) or endodermal origin (lungs, gastrointestinal tract, liver, pancreas). The parenchyma of a few organs (spleen, kidneys, heart) is of mesodermal origin. The stroma of all organs is of mesodermal origin" xsd:string {source="WP"}
property_value: UBPROP:0000012 "the FMA definition is more restrictive, and limits this to solid organs. This would seem to cause problems for the lung parenchyma, except FMA classifies Lung as solid rather than cavitated" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0000355
name: pharyngeal mucosa
namespace: uberon
alt_id: UBERON:0003344
def: "A mucosa that is part of a pharynx [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of organ of pharynx" EXACT [OBOL:automatic]
synonym: "mucosa of pharynx" EXACT [OBOL:automatic]
synonym: "mucous membrane of pharynx" EXACT [FMA:55031, OBOL:automatic]
synonym: "mucous membrane of the pharynx" RELATED [BTO:0001047]
synonym: "organ mucosa of pharynx" EXACT [OBOL:automatic]
synonym: "pharynx mucosa" EXACT [OBOL:automatic]
synonym: "pharynx mucosa of organ" EXACT [OBOL:automatic]
synonym: "pharynx mucous membrane" EXACT [OBOL:automatic]
synonym: "pharynx organ mucosa" EXACT [OBOL:automatic]
synonym: "tunica mucosa pharyngea" EXACT OMO:0003011 [FMA:55031, FMA:TA]
synonym: "tunica mucosa pharyngis" EXACT []
xref: BTO:0001047
xref: EMAPA:26957
xref: FMA:55031
xref: MA:0003143
xref: SCTID:362121003
is_a: UBERON:0004785 ! respiratory system mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001042 ! chordate pharynx
relationship: part_of UBERON:0001042 ! chordate pharynx

[Term]
id: UBERON:0000358
name: blastocyst
namespace: uberon
def: "The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]." [GO:0001824, Wikipedia:Blastocyst]
subset: efo_slim
synonym: "blastocystis" RELATED OMO:0003011 [Wikipedia:Blastocyst]
synonym: "blastula" RELATED [FMA:83041]
xref: BTO:0001099
xref: CALOHA:TS-0076
xref: EFO:0000295
xref: EMAPA:36035
xref: EV:0100394
xref: FMA:83041
xref: GAID:1153
xref: MESH:D001755
xref: NCIT:C13739
xref: SCTID:308837009
xref: UMLS:C1281743 {source="ncithesaurus:Blastocyst"}
xref: Wikipedia:Blastocyst
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0000085 ! morula
relationship: existence_starts_and_ends_during UBERON:0000108 ! blastula stage
relationship: has_part UBERON:0000087 ! inner cell mass
relationship: has_part UBERON:0000088 ! trophoblast
relationship: only_in_taxon NCBITaxon:32525 ! Theria <mammals>
relationship: part_of UBERON:0000307 ! blastula
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI
property_value: editor_note "Gilbert fig11.32 has blastocyst has giving rise to ICM and trophoblast (which in this source is a synonym for trophectoderm)" xsd:string

[Term]
id: UBERON:0000361
name: red bone marrow
namespace: uberon
def: "The red vascular substance consisting of connective tissue and blood vessels, containing primitive blood cells, macrophages, megakaryocytes, and fat cells. Red marrow is found in the cavities of many bones. It manufactures and releases leukocytes and erythrocytes into the bloodstream." [http://medical-dictionary.thefreedictionary.com/red+marrow]
synonym: "medulla ossium rubra" EXACT OMO:0003011 [BTO:0001160]
synonym: "parenchyma of none marrow marrow" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "parenchymal red marrow" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "red marrow" EXACT [BTO:0001160]
xref: BTO:0001160
xref: FMA:74595
xref: SCTID:328538003
xref: SCTID:75330005
is_a: UBERON:0002371 ! bone marrow
intersection_of: UBERON:0002371 ! bone marrow
intersection_of: composed_primarily_of CL:0000988 ! hematopoietic cell
relationship: composed_primarily_of CL:0000988 ! hematopoietic cell
relationship: part_of UBERON:0012429 ! hematopoietic tissue

[Term]
id: UBERON:0000371
name: syncytiotrophoblast
namespace: uberon
def: "Extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated)." [http://embryology.med.unsw.edu.au/Notes/placenta5.htm, Wikipedia:Syncytiotrophoblast]
synonym: "syncitiotrophoblast" RELATED []
synonym: "syncitiotrophoblastus" RELATED OMO:0003011 [Wikipedia:Syncytiotrophoblast]
synonym: "syncytial trophoblast" EXACT [FMA:83040]
synonym: "syntrophoblast" RELATED []
synonym: "syntrophoblast layer" EXACT [ISBN:0073040584]
xref: BTO:0001335
xref: EHDAA:129
xref: EHDAA:91
xref: EMAPA:16068
xref: FMA:83040
xref: NCIT:C33918
xref: SCTID:256965005
xref: UMLS:C1135936 {source="ncithesaurus:Syncytiotrophoblast"}
xref: Wikipedia:Syncytiotrophoblast
is_a: UBERON:0002050 {source="FMA"} ! embryonic structure
relationship: composed_primarily_of CL:0000525 ! syncytiotrophoblast cell
relationship: part_of UBERON:0004364 {source="EMAPA"} ! ectoplacental cone
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/df/Gray36.png" xsd:anyURI

[Term]
id: UBERON:0000377
name: maxillary nerve
namespace: uberon
def: "The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses." [MP:0009799, Wikipedia:Maxillary_nerve]
subset: human_reference_atlas
subset: pheno_slim
synonym: "maxillary division [V2]" EXACT [FMA:52724]
synonym: "maxillary division [Vb]" EXACT [FMA:52724]
synonym: "maxillary division of fifth cranial nerve" EXACT [FMA:52724]
synonym: "maxillary division of trigeminal nerve (Vb; V2)" EXACT [FMA:52724]
synonym: "maxillary nerve [V2]" EXACT [FMA:52724]
synonym: "maxillary nerve [Vb]" EXACT [FMA:52724]
synonym: "n. maxillaris" RELATED OMO:0003011 [Wikipedia:Maxillary_nerve]
synonym: "nervus maxillaris" RELATED [BTO:0001378]
synonym: "nervus maxillaris (Vb; V2)" EXACT [FMA:52724]
synonym: "nervus maxillaris [v2]" EXACT OMO:0003011 [FMA:52724, FMA:TA]
synonym: "nervus maxillaris [vb]" EXACT OMO:0003011 [FMA:52724, FMA:TA]
synonym: "ramus maxillaris (ramus V2)" EXACT [AAO:0010670]
synonym: "second division of fifth cranial nerve" EXACT [FMA:52724]
synonym: "second division of trigeminal nerve" EXACT [FMA:52724]
synonym: "trigeminal nerve maxillary division" RELATED [EMAPA:17799]
synonym: "trigeminal V nerve maxillary division" EXACT [MA:0001103]
xref: AAO:0010670
xref: BTO:0001378
xref: EHDAA2:0002087
xref: EMAPA:17799
xref: FMA:52724
xref: GAID:836
xref: MA:0001103
xref: MESH:D008442
xref: SCTID:280211001
xref: VHOG:0001346
xref: Wikipedia:Maxillary_nerve
is_a: UBERON:0011779 ! nerve of head region
relationship: branching_part_of UBERON:0001645 ! trigeminal nerve
relationship: part_of UBERON:0001645 ! trigeminal nerve
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/a9/Gray779.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Medial ramus (sensory) of the trigeminal nerve.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010670", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000002 "relationship loss: part_of trunk maxillary-mandibularis (AAO:0010669)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010670", ontology="AAO"}

[Term]
id: UBERON:0000379
name: tracheal mucosa
namespace: uberon
def: "A mucosa that is part of a respiratory airway." [OBOL:automatic]
synonym: "mucosa of organ of trachea" EXACT [OBOL:automatic]
synonym: "mucosa of organ of windpipe" EXACT [OBOL:automatic]
synonym: "mucosa of trachea" EXACT [OBOL:automatic]
synonym: "mucosa of windpipe" EXACT [OBOL:automatic]
synonym: "mucous membrane of trachea" EXACT [FMA:7471, OBOL:automatic]
synonym: "mucous membrane of windpipe" EXACT [OBOL:automatic]
synonym: "organ mucosa of trachea" EXACT [OBOL:automatic]
synonym: "organ mucosa of windpipe" EXACT [OBOL:automatic]
synonym: "trachea mucosa" EXACT [OBOL:automatic]
synonym: "trachea mucosa of organ" EXACT [OBOL:automatic]
synonym: "trachea mucous membrane" EXACT [OBOL:automatic]
synonym: "trachea organ mucosa" EXACT [OBOL:automatic]
synonym: "tracheal mucous membrane" EXACT [FMA:7471]
synonym: "tunica mucosa (tracheae)" EXACT [FMA:7471]
synonym: "tunica mucosa tracheae" EXACT OMO:0003011 [FMA:7471, FMA:TA]
synonym: "windpipe mucosa" EXACT [OBOL:automatic]
synonym: "windpipe mucosa of organ" EXACT [OBOL:automatic]
synonym: "windpipe mucous membrane" EXACT [OBOL:automatic]
synonym: "windpipe organ mucosa" EXACT [OBOL:automatic]
xref: BTO:0001390
xref: FMA:7471
xref: SCTID:660006
is_a: UBERON:0004785 ! respiratory system mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001005 ! respiratory airway
relationship: part_of UBERON:0001005 ! respiratory airway

[Term]
id: UBERON:0000383
name: musculature of body
namespace: uberon
def: "The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]." [VSAO:0000033]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
synonym: "muscle system" EXACT []
synonym: "muscle system of body" EXACT []
synonym: "muscular system" EXACT [FMA:72954]
synonym: "musculature system" EXACT [BILA:0000088]
synonym: "muskelsystem" RELATED [BTO:0001485]
synonym: "set of all muscles" EXACT [FMA:72954]
synonym: "set of muscles of body" EXACT [FMA:72954]
synonym: "vertebrate muscular system" EXACT [BTO:0001369]
xref: AAO:0000307
xref: BILA:0000088
xref: BTO:0001369
xref: BTO:0001485
xref: EFO:0000801
xref: EMAPA:35578
xref: FMA:72954
xref: MA:0002888
xref: MAT:0000025
xref: MIAA:0000025
xref: VSAO:0000033
xref: XAO:0004042
is_a: UBERON:0011216 ! organ system subdivision
intersection_of: UBERON:0011216 ! organ system subdivision
intersection_of: composed_primarily_of UBERON:0001015 ! musculature
relationship: capable_of GO:0003012 ! muscle system process
relationship: composed_primarily_of UBERON:0001015 ! musculature
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: editor_note "consider whether this should be restricted to skeletal musculature. See https://github.com/obophenotype/uberon/issues/77" xsd:string
property_value: RO:0002161 NCBITaxon:6040
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anatomical system that consists of the muscles of the body.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000033", ontology="VSAO", source="VSAO:curator"}
property_value: UBPROP:0000012 "we place the MA term musculature here, rather than under uberon:musculature, as this seems more appropriate given the structure of MA" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0000389
name: lens cortex
namespace: uberon
def: "Tissue that surrounds the lens nucleus." [http://www.thefreedictionary.com/lens+cortex]
subset: human_reference_atlas
synonym: "cortex of lens" EXACT [FMA:58970]
xref: BTO:0001632
xref: CALOHA:TS-0542
xref: FMA:58970
xref: MESH:D007904
xref: SCTID:280626006
is_a: UBERON:0000479 ! tissue
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000479 ! tissue
intersection_of: surrounds UBERON:0000390 ! lens nucleus
relationship: develops_from UBERON:0005614 ! lens anterior epithelium
relationship: part_of UBERON:0000965 ! lens of camera-type eye
relationship: surrounds UBERON:0000390 ! lens nucleus
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000390
name: lens nucleus
namespace: uberon
def: "The core of the crystalline lens, surrounded by the cortex." [BTO:0001633]
subset: human_reference_atlas
synonym: "nucleus of lens" EXACT [FMA:58971]
xref: BTO:0001633
xref: FMA:58971
xref: MESH:D007907
xref: SCTID:280628007
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0034944 ! zone of organ
intersection_of: UBERON:0034944 ! zone of organ
intersection_of: surrounded_by UBERON:0000389 ! lens cortex
relationship: develops_from UBERON:0005614 ! lens anterior epithelium
relationship: part_of UBERON:0000965 ! lens of camera-type eye
relationship: surrounded_by UBERON:0000389 ! lens cortex
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000397
name: colonic epithelium
namespace: uberon
def: "An epithelium that is part of a colon [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
subset: vertebrate_core
synonym: "colon epithelial tissue" EXACT [OBOL:automatic]
synonym: "colon epithelium" EXACT [FMA:17302, OBOL:automatic]
synonym: "epithelial tissue of colon" EXACT [OBOL:automatic]
synonym: "epithelial tissue of large bowel" EXACT [OBOL:automatic]
synonym: "epithelium of colon" EXACT [OBOL:automatic]
synonym: "epithelium of large bowel" EXACT [OBOL:automatic]
synonym: "large bowel epithelial tissue" EXACT [OBOL:automatic]
synonym: "large bowel epithelium" EXACT [OBOL:automatic]
synonym: "posterior intestine epithelium" EXACT [ZFA:0005128]
xref: BTO:0001709
xref: CALOHA:TS-0163
xref: EMAPA:18941
xref: FMA:17302
xref: MA:0003195
xref: SCTID:42978003
xref: TAO:0005128
xref: ZFA:0005128
is_a: UBERON:0001278 ! epithelium of large intestine
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Intestinal epithelium which lines the lumen of the posterior intestine.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005128", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0000409
name: serous gland
namespace: uberon
def: "A gland in which the principal secretory cells are serous secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm]
subset: organ_slim
subset: pheno_slim
xref: BTO:0001837
xref: EMAPA:37950 {source="MA:th"}
xref: FMA:62889
xref: Wikipedia:Serous_gland
is_a: UBERON:0002365 ! exocrine gland
intersection_of: UBERON:0002365 ! exocrine gland
intersection_of: has_part CL:0000313 ! serous secreting cell
relationship: has_part CL:0000313 ! serous secreting cell
relationship: has_part UBERON:0013232 ! serous acinus
relationship: produces UBERON:0007794 ! secretion of serous gland
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png" xsd:anyURI
property_value: UBPROP:0000001 "glands that secrete watery albuminous material that often contains enzymes[MP:0008052]." xsd:string {source="MP:0008052"}

[Term]
id: UBERON:0000414
name: mucous gland
namespace: uberon
def: "A gland in which the principal secretory cells are mucus secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm]
subset: organ_slim
synonym: "glandula mucosa" EXACT OMO:0003011 [Wikipedia:Mucous_gland]
synonym: "muciparous gland" RELATED [BTO:0001979]
synonym: "mucous secreting gland" RELATED []
synonym: "mucus gland" RELATED []
synonym: "mucus-secreting gland" RELATED []
xref: AAO:0010601
xref: BTO:0001979
xref: EMAPA:37913 {source="MA:th"}
xref: FMA:62888
xref: Wikipedia:Mucous_gland
is_a: UBERON:0002365 ! exocrine gland
intersection_of: UBERON:0002365 ! exocrine gland
intersection_of: has_part CL:0000319 ! mucus secreting cell
relationship: capable_of GO:0070254 ! mucus secretion
relationship: has_part CL:0000319 ! mucus secreting cell
relationship: produces UBERON:0000912 ! mucus
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png" xsd:anyURI
property_value: UBPROP:0000008 "In frogs and salamanders, this is the smaller of the two types of gland, the other being the granular (poison) gland. In these species the mucous gland is a cluster of cells that release secretion into a common duct[Kardong]" xsd:string {scope="NCBITaxon:8292", source="ISBN:0073040584"}

[Term]
id: UBERON:0000415
name: artery wall
namespace: uberon
def: "An anatomical wall that is part of an artery [Automatically generated definition]." [OBOL:automatic]
synonym: "arterial wall" EXACT [FMA:14155]
synonym: "wall of artery" EXACT [FMA:14155]
xref: BTO:0002009
xref: FMA:14155
xref: galen:ArterialWall
is_a: UBERON:0035965 ! wall of blood vessel
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001637 ! artery
relationship: part_of UBERON:0001637 ! artery

[Term]
id: UBERON:0000440
name: trabecula
namespace: uberon
def: "A small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue. On histological section, a trabecula can look like a septum, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like. Trabeculae are usually composed of dense fibrous tissue, i.e. mainly of collagen, and in most cases provide mechanical strengthening or stiffening to a soft solid organ, such as the spleen. They can be composed of other materials, such as bone or muscle[WP]." [GO:0060343, Wikipedia:Trabecula]
subset: grouping_class
subset: pheno_slim
synonym: "trabeculae" EXACT OMO:0003004 []
xref: BTO:0002501
xref: FMA:85273
xref: Wikipedia:Trabecula
is_a: UBERON:0000064 ! organ part
relationship: has_part UBERON:0002384 ! connective tissue
relationship: has_quality PATO:0001873 ! cylindrical
property_value: UBPROP:0000007 "trabecular" xsd:string

[Term]
id: UBERON:0000442
name: right testicular vein
namespace: uberon
def: "A vein that drains the left pampiniform plexus and empties into the left renal vein." [Dorlands_Medical_Dictionary:MerckSource]
subset: human_reference_atlas
synonym: "right spermatic vein" EXACT [MA:0002220]
synonym: "vena testicularis (adrenalis) dextra" EXACT [FMA:14341]
synonym: "vena testicularis dextra" RELATED [BTO:0002679]
synonym: "vena testicularis sinistra" RELATED [BTO:0002680]
xref: BTO:0002679
xref: EMAPA:37383 {source="MA:th"}
xref: FMA:14341
xref: MA:0002220
xref: NCIT:C52697
xref: SCTID:53500001
is_a: UBERON:0001144 ! testicular vein
intersection_of: UBERON:0001144 ! testicular vein
intersection_of: drains UBERON:0004534 ! right testis
relationship: connected_to UBERON:0001142 ! left renal vein
relationship: drains UBERON:0004534 ! right testis
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000443
name: left testicular vein
namespace: uberon
def: "A vein that drains the right pampiniform plexus and empties into the inferior vena cava." [Dorlands_Medical_Dictionary:MerckSource]
subset: human_reference_atlas
synonym: "left spermatic vein" EXACT [MA:0002219]
synonym: "vena testicularis dextra" RELATED [BTO:0002679]
synonym: "vena testicularis sinistra" RELATED [BTO:0002680]
xref: BTO:0002680
xref: EMAPA:37167 {source="MA:th"}
xref: FMA:14345
xref: MA:0002219
xref: NCIT:C52696
xref: SCTID:90988008
is_a: UBERON:0001144 ! testicular vein
intersection_of: UBERON:0001144 ! testicular vein
intersection_of: drains UBERON:0004533 ! left testis
relationship: connected_to UBERON:0001142 ! left renal vein
relationship: drains UBERON:0004533 ! left testis
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000456
name: secretion of exocrine gland
namespace: uberon
alt_id: UBERON:0006540
def: "A portion of organism substance that is produced by exocrine glands." [http://orcid.org/0000-0002-6601-2165]
synonym: "bodily secretion" EXACT [MESH:D012634]
synonym: "exocrine gland fluid" RELATED []
synonym: "exocrine gland fluid or secretion" RELATED []
synonym: "exocrine gland fluid/secretion" EXACT [MA:0002504]
synonym: "exocrine gland secretion" RELATED []
synonym: "external secretion" RELATED [BTO:0002977]
synonym: "secreted substance" EXACT []
synonym: "secretion" BROAD [FMA:9675]
xref: AEO:0001005
xref: BTO:0002977
xref: BTO:0002979
xref: EMAPA:36535
xref: FMA:9675
xref: galen:Secretion
xref: MA:0002504
xref: MESH:D012634
xref: NCIT:C34062
xref: UMLS:C1516992 {source="ncithesaurus:Exocrine_Gland_Fluid_or_Secretion"}
is_a: UBERON:0000463 ! organism substance
intersection_of: UBERON:0000463 ! organism substance
intersection_of: produced_by UBERON:0002365 ! exocrine gland
relationship: produced_by UBERON:0002365 ! exocrine gland
property_value: UBPROP:0000012 "BTO has two distunct classes, with exocrine glandular secretion a subtype of secretion - however, all examples in BTO directly under secretion appear to be exocrine gland secretions" xsd:string {external_ontology="BTO"}

[Term]
id: UBERON:0000459
name: uterine wall
namespace: uberon
def: "An anatomical wall that is part of a uterus [Automatically generated definition]." [OBOL:automatic]
synonym: "anatomical wall of uterus" EXACT [OBOL:automatic]
synonym: "uterus anatomical wall" EXACT [OBOL:automatic]
synonym: "uterus wall" EXACT [OBOL:automatic]
synonym: "wall of uterus" EXACT [OBOL:automatic]
xref: BTO:0003083
xref: FMA:17560
xref: SCTID:245485002
is_a: UBERON:0000060 ! anatomical wall
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000995 ! uterus
relationship: part_of UBERON:0000995 ! uterus

[Term]
id: UBERON:0000463
name: organism substance
namespace: uberon
def: "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." [http://orcid.org/0000-0001-9114-8737]
subset: common_anatomy
subset: pheno_slim
subset: upper_level
synonym: "body fluid or substance" EXACT [MA:0002450]
synonym: "body substance" EXACT [FMA:9669]
synonym: "organism substance" EXACT [CARO:0000004]
synonym: "portion of body substance" EXACT [FMA:9669]
synonym: "portion of organism substance" EXACT [ZFA:0001487]
xref: AAO:0010839
xref: AEO:0000004
xref: BILA:0000004
xref: CALOHA:TS-2101
xref: CARO:0000004
xref: EHDAA2:0003004
xref: EMAPA:35178
xref: FBbt:00007019 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:9669
xref: galen:BodySubstance
xref: HAO:0000004
xref: MA:0002450
xref: NCIT:C13236
xref: SPD:0000008
xref: TAO:0001487
xref: TGMA:0001824
xref: VHOG:0001726
xref: XAO:0004001
xref: ZFA:0001487
is_a: UBERON:0000465 ! material anatomical entity
relationship: has_quality PATO:0002198 ! quality of a substance
relationship: part_of UBERON:0000468 {notes="this relationship may be too strong and may be weakened in future"} ! multicellular organism
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000464
name: anatomical space
namespace: uberon
def: "Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." [http://orcid.org/0000-0001-9114-8737]
subset: common_anatomy
subset: upper_level
synonym: "anatomical spaces" RELATED OMO:0003004 [ZFA:0001643]
synonym: "lumen" BROAD []
synonym: "lumen space" EXACT []
synonym: "space" BROAD []
xref: AAO:0010110
xref: AEO:0000005
xref: BILA:0000005
xref: CARO:0000005
xref: EHDAA2:0003005
xref: FBbt:00007017 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:5897
xref: HAO:0000005
xref: NCIT:C94478
xref: TAO:0001668
xref: TGMA:0001825
xref: UMLS:C0524461 {source="ncithesaurus:Lumen_Space"}
xref: VHOG:0001728
xref: XAO:0003190
xref: ZFA:0001643
is_a: UBERON:0000466 ! immaterial anatomical entity
relationship: surrounded_by UBERON:0000061 ! anatomical structure
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000465
name: material anatomical entity
namespace: uberon
def: "Anatomical entity that has mass." [http://orcid.org/0000-0001-9114-8737]
subset: common_anatomy
subset: upper_level
xref: AAO:0010264
xref: AEO:0000006
xref: BILA:0000006
xref: CARO:0000006
xref: EHDAA2:0003006
xref: FBbt:00007016 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:67165
xref: HAO:0000006
xref: TAO:0001836
xref: TGMA:0001826
xref: VHOG:0001721
is_a: BFO:0000040 ! material entity
is_a: UBERON:0001062 ! anatomical entity
disjoint_from: UBERON:0000466 ! immaterial anatomical entity
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000466
name: immaterial anatomical entity
namespace: uberon
def: "Anatomical entity that has no mass." [http://orcid.org/0000-0001-9114-8737]
subset: common_anatomy
subset: upper_level
synonym: "immaterial physical anatomical entity" EXACT [FMA:67112]
xref: AAO:0010265
xref: AEO:0000007
xref: BILA:0000007
xref: CARO:0000007
xref: EHDAA2:0003007
xref: FBbt:00007015 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:67112
xref: HAO:0000007
xref: TAO:0001835
xref: TGMA:0001827
xref: VHOG:0001727
is_a: BFO:0000141 ! immaterial entity
is_a: UBERON:0001062 ! anatomical entity
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000467
name: anatomical system
namespace: uberon
def: "Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function." [CARO:0000011]
subset: common_anatomy
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: upper_level
synonym: "anatomical systems" RELATED OMO:0003004 [ZFA:0001439]
synonym: "body system" EXACT [BIRNLEX:14]
synonym: "connected anatomical system" EXACT [CARO:0000011]
synonym: "organ system" EXACT []
synonym: "system" BROAD [GO:0048731]
xref: AAO:0000007
xref: AEO:0000011
xref: BILA:0000011
xref: BIRNLEX:14
xref: BSA:0000049
xref: CALOHA:TS-2088
xref: CARO:0000011
xref: EHDAA2:0003011
xref: EHDAA:392
xref: EMAPA:16103
xref: EV:0100000
xref: FBbt:00004856 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:7149
xref: galen:AnatomicalSystem
xref: HAO:0000011
xref: IDOMAL:0002460 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: MA:0000003
xref: NCIT:C12919
xref: SCTID:278195005
xref: TAO:0001439
xref: TGMA:0001831
xref: UMLS:C0460002 {source="ncithesaurus:Organ_System"}
xref: VHOG:0001725
xref: WBbt:0005746
xref: WBbt:0005763
xref: Wikipedia:Organ_system
xref: XAO:0003002
xref: ZFA:0001439
is_a: UBERON:0000061 ! anatomical structure
relationship: existence_starts_during_or_after UBERON:0000111 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! organogenesis stage
relationship: has_part UBERON:0000062 ! organ
relationship: part_of UBERON:0000468 ! multicellular organism
relationship: seeAlso EHDAA2:0001330
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0000468
name: multicellular organism
namespace: uberon
def: "Anatomical structure that is an individual member of a species and consists of more than one cell." [CARO:0000012, http://orcid.org/0000-0001-9114-8737, Wikipedia:Multi-cellular_organism]
subset: common_anatomy
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: upper_level
synonym: "body" RELATED [AEO:0000103, BIRNLEX:18, FMA:256135, NCIT:C13041]
synonym: "Koerper" RELATED [BTO:0001489]
synonym: "multi-cellular organism" EXACT [CARO:0000012]
synonym: "organism" BROAD [FBbt:00000001, VHOG:0000671, WBbt:0007833]
synonym: "whole body" RELATED [BTO:0001489]
synonym: "whole organism" RELATED [FBbt:00000001]
xref: AAO:0010026
xref: AEO:0000191
xref: BILA:0000012
xref: BIRNLEX:18
xref: BSA:0000038
xref: BTO:0000042
xref: CARO:0000012
xref: EFO:0002906
xref: EHDAA2:0003103
xref: EHDAA2:0003191
xref: EHDAA:1
xref: EMAPA:25765
xref: EV:0100016
xref: FBbt:00000001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:256135
xref: galen:Organism
xref: HAO:0000012
xref: NCIT:C13041
xref: ncithesaurus:Whole_Organism
xref: SCTID:243928005
xref: TADS:0000001
xref: TAO:0001094
xref: TGMA:0001832
xref: VHOG:0000671
xref: WBbt:0007833
xref: Wikipedia:Multi-cellular_organism
xref: XAO:0003004
xref: ZFA:0001094
is_a: UBERON:0010000 ! multicellular anatomical structure
property_value: editor_note "TODO - split body and mc organism? body continues after death stage" xsd:string
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751
property_value: UBPROP:0000007 "organismal" xsd:string

[Term]
id: UBERON:0000471
name: compound organ component
namespace: uberon
def: "Multi-tissue structure that is part of a compound organ." [CARO:0000019, http://orcid.org/0000-0001-9114-8737]
subset: upper_level
synonym: "compound organ components" RELATED OMO:0003004 [ZFA:0001489]
xref: AAO:0010017
xref: AEO:0000019
xref: BILA:0000019
xref: CARO:0000019
xref: EHDAA2:0003019
xref: HAO:0000019
xref: TAO:0001489
xref: TGMA:0001835
xref: XAO:0003039
xref: ZFA:0001489
is_a: UBERON:0000481 ! multi-tissue structure
relationship: part_of UBERON:0003103 ! compound organ
property_value: curator_notes "this class was introduced for consistency with CARO, however, it has yet to be used in this or other ontologies. It may be retired in the future" xsd:string

[Term]
id: UBERON:0000473
name: testis
namespace: uberon
alt_id: UBERON:0002117
def: "A gonad of a male animal. A gonad produces and releases sperm." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "gonad of male genitalia" EXACT [OBOL:automatic]
synonym: "gonad of male reproductive system" EXACT [OBOL:automatic]
synonym: "male gonad" EXACT [OBOL:automatic]
synonym: "orchis" RELATED [BTO:0001363]
synonym: "testes" RELATED OMO:0003004 []
synonym: "testicle" EXACT [FMA:7210]
synonym: "testiculus" RELATED OMO:0003011 [BTO:0001363]
xref: AAO:0000606
xref: BILA:0000124
xref: BSA:0000085
xref: BTO:0001363
xref: CALOHA:TS-1030
xref: EFO:0000984
xref: EHDAA2:0002007
xref: EHDAA:8146
xref: EMAPA:17972
xref: EV:0100102
xref: FBbt:00004928 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:7210
xref: GAID:396
xref: galen:Testis
xref: HAO:0001007
xref: MA:0000411
xref: MAT:0000132
xref: MESH:D013737
xref: MIAA:0000132
xref: NCIT:C12412
xref: SCTID:181431007
xref: TAO:0000598
xref: UMLS:C0039597 {source="ncithesaurus:Testis"}
xref: VHOG:0000252
xref: WBbt:0006794
xref: Wikipedia:Testis
xref: XAO:0000157
xref: ZFA:0000598
is_a: UBERON:0000991 ! gonad
is_a: UBERON:0003135 ! male reproductive organ
intersection_of: UBERON:0000991 ! gonad
intersection_of: part_of UBERON:0000079 ! male reproductive system
disjoint_from: UBERON:0000992 ! ovary
disjoint_from: UBERON:0009117 ! indifferent gonad
relationship: develops_from UBERON:0009117 ! indifferent gonad
relationship: in_lateral_side_of UBERON:0000468 {gci_relation="part_of", gci_filler="NCBITaxon:7742", notes="vertebrates"} ! multicellular organism
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c3/Gray1144.png" xsd:anyURI
property_value: UBPROP:0000001 "Male reproductive organ.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000598", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "(...) while it is likely that Urbilateria lacked a complex somatic reproductive system, it is at present impossible to speculate on whether or not it possessed a true gonad, let alone any other somatic adaptations for reproduction (reference 1); Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved (reference 2).[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000252", ontology="VHOG", source="DOI:10.1093/icb/icm052 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across the Bilateria. Integrative and Comparative Biology (2007), DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T and Capel B, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "testicular" xsd:string
property_value: UBPROP:0000008 "The testes are descended in metatherian and eutherian mammals, first transabdominally, then inguinoscrotally" xsd:string {source="ISBN:0123971756", taxon="NCBITaxon:40674"}

[Term]
id: UBERON:0000474
name: female reproductive system
namespace: uberon
def: "The organs and associated structures associated with bearing offspring in a female animal." [http://orcid.org/0000-0002-6601-2165, MP:0001119, Wikipedia:Female_genitalia]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "female genital system" RELATED []
synonym: "female genital tract" RELATED []
synonym: "female genitalia" RELATED []
synonym: "female genitals" RELATED OMO:0003004 [XAO:0000156]
synonym: "female organism genitalia" EXACT [OBOL:automatic]
synonym: "female organism reproductive system" EXACT [OBOL:automatic]
synonym: "female reproductive tract" RELATED [MA:0000381]
synonym: "genitalia of female organism" EXACT [OBOL:automatic]
synonym: "gynaecological tissue" RELATED [BTO:0000083]
synonym: "reproductive system of female organism" EXACT [OBOL:automatic]
synonym: "systema genitale femininum" RELATED [BTO:0000083]
xref: BTO:0000083
xref: CALOHA:TS-1303
xref: EFO:0000969
xref: EHDAA2:0000506
xref: EHDAA:8116
xref: EMAPA:17959
xref: EV:0100110
xref: FBbt:00004864 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:45663
xref: GAID:364
xref: HAO:0000324
xref: MA:0000381
xref: MESH:D005836
xref: MIAA:0000028
xref: NCIT:C12402
xref: SCTID:361386004
xref: TGMA:0000635
xref: UMLS:C0700038 {source="ncithesaurus:Female_Reproductive_System"}
xref: VHOG:0000726
xref: Wikipedia:Female_genitalia
xref: WikipediaCategory:Female_reproductive_system
xref: XAO:0000156
is_a: UBERON:0000990 ! reproductive system
intersection_of: UBERON:0000990 ! reproductive system
intersection_of: part_of UBERON:0003100 ! female organism
relationship: part_of UBERON:0003100 ! female organism
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "By far, sexual reproduction is the more common pattern among living vertebrate forms and its widespread occurrence suggests that it is the plesiomorphic, or primitive, reproductive mode among the vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000726", ontology="VHOG", source="ISBN:978-0792383369 Lombardi J, Comparative vertebrate reproduction (1998) p.43", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000475
name: organism subdivision
namespace: uberon
def: "Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument." [CARO:0000032, CARO:DOS, http://orcid.org/0000-0001-9114-8737]
subset: common_anatomy
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: upper_level
synonym: "anatomic region" EXACT [MA:0002433]
synonym: "body part" RELATED []
synonym: "body region" RELATED [FMA:7153]
synonym: "cardinal body part" RELATED [FMA:7153]
xref: AAO:0010053
xref: AEO:0000032
xref: BILA:0000032
xref: BIRNLEX:7
xref: CALOHA:TS-2084
xref: CARO:0000032
xref: EFO:0000808
xref: EHDAA2:0003032
xref: EMAPA:36031
xref: FBbt:00007009 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:7153
xref: galen:BodyPart
xref: HAO:0000032
xref: MA:0002433
xref: MAT:0000293
xref: MESH:D001829
xref: MIAA:0000293
xref: NCIT:C32221
xref: TAO:0001308
xref: TGMA:0001840
xref: UMLS:C0229962 {source="ncithesaurus:Body_Part"}
xref: VHOG:0001758
xref: Wikipedia:Body_part
xref: XAO:0003013
xref: ZFA:0001308
is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure
relationship: has_part UBERON:0000075 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! subdivision of skeletal system
relationship: has_part UBERON:0034929 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! external soft tissue zone
relationship: overlaps UBERON:0001009 {gci_filler="NCBITaxon:33213", gci_relation="in_taxon"} ! circulatory system
relationship: overlaps UBERON:0001015 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! musculature
relationship: overlaps UBERON:0001016 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! nervous system
relationship: overlaps UBERON:0001434 {gci_filler="NCBITaxon:33213", gci_relation="in_taxon"} ! skeletal system
relationship: overlaps UBERON:0002416 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! integumental system
relationship: part_of UBERON:0000468 ! multicellular organism
property_value: editor_note "Reflects CARO2. todo - check the inclusion of FMA 'cardinal body part here', and check child terms for consistency" xsd:string
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000476
name: acellular anatomical structure
namespace: uberon
def: "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue." [http://orcid.org/0000-0001-9114-8737]
subset: common_anatomy
subset: vertebrate_core
synonym: "acellular anatomical structures" RELATED OMO:0003004 [ZFA:0000382]
xref: AAO:0010268
xref: AEO:0000040
xref: BILA:0000040
xref: CARO:0000040
xref: EHDAA2:0003040
xref: FBbt:00007013 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:63863
xref: HAO:0000040
xref: TAO:0000382
xref: TGMA:0001841
xref: XAO:0003162
xref: ZFA:0000382
is_a: UBERON:0000061 ! anatomical structure
disjoint_from: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000477
name: anatomical cluster
namespace: uberon
def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277]
subset: common_anatomy
subset: upper_level
xref: FBbt:00007277 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: VHOG:0001737
is_a: UBERON:0034923 ! disconnected anatomical group
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000478
name: extraembryonic structure
namespace: uberon
def: "A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis." [CARO:DOS, http://orcid.org/0000-0001-9114-8737, https://cedar.bio.indiana.edu/trac/env/ontologies/ticket/279]
comment: see also conceptus extraembryonic component in EHDAA2.
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "extra-embryonic structure" EXACT []
synonym: "extraembryonic structures" RELATED OMO:0003004 [ZFA:0000020]
synonym: "extraembryonic tissue" RELATED []
xref: AAO:0010020
xref: AEO:0000042
xref: BILA:0000042
xref: CALOHA:TS-2119
xref: CARO:0000042
xref: EHDAA2:0003042
xref: EHDAA:46
xref: FBbt:00005835 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:85537
xref: HAO:0000042
xref: NCIT:C34055
xref: SCTID:314908006
xref: TAO:0000020
xref: TGMA:0001843
xref: UMLS:C1282438 {source="ncithesaurus:Extraembryonic_Structure"}
xref: VHOG:0000292
xref: XAO:0004005
xref: ZFA:0000020
is_a: UBERON:0005423 ! developing anatomical structure
intersection_of: UBERON:0005423 ! developing anatomical structure
intersection_of: part_of UBERON:0016887 ! entire extraembryonic component
relationship: existence_starts_and_ends_during UBERON:0000068 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! embryo stage
relationship: part_of UBERON:0016887 ! entire extraembryonic component

[Term]
id: UBERON:0000479
name: tissue
namespace: uberon
def: "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." [CARO:0000043]
subset: common_anatomy
subset: pheno_slim
subset: upper_level
synonym: "portion of tissue" EXACT [CARO:0000043]
synonym: "simple tissue" NARROW [AEO:0000043]
synonym: "tissue portion" EXACT []
xref: AAO:0000607
xref: AAO:0010054
xref: AEO:0000043
xref: BILA:0000043
xref: BIRNLEX:19
xref: CALOHA:TS-2090
xref: CARO:0000043
xref: EHDAA2:0003043
xref: EMAPA:35868
xref: FBbt:00007003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:9637
xref: galen:Tissue
xref: HAO:0000043
xref: MA:0003002
xref: MESH:D014024
xref: NCIT:C12801
xref: TAO:0001477
xref: TGMA:0001844
xref: UMLS:C0040300 {source="ncithesaurus:Tissue"}
xref: VHOG:0001757
xref: WBbt:0005729
xref: XAO:0003040
xref: ZFA:0001477
is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure
relationship: has_part GO:0031012 ! extracellular matrix
relationship: part_of UBERON:0000468 ! multicellular organism
property_value: editor_note "changed label and definition to reflect CARO2" xsd:string
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000481
name: multi-tissue structure
namespace: uberon
def: "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." [CARO:0000055, http://orcid.org/0000-0001-9114-8737]
subset: common_anatomy
subset: upper_level
synonym: "multi-tissue structures" RELATED OMO:0003004 [ZFA:0001488]
xref: AAO:0010048
xref: AEO:0000055
xref: BILA:0000055
xref: CARO:0000055
xref: EHDAA2:0003055
xref: FBbt:00007010 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: HAO:0000055
xref: TAO:0001488
xref: TGMA:0001847
xref: VHOG:0001762
xref: XAO:0003037
xref: ZFA:0001488
is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure
relationship: has_part UBERON:0000479 ! tissue
relationship: part_of NCBITaxon:6072 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! Eumetazoa
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0000483
name: epithelium
namespace: uberon
def: "Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]." [http://orcid.org/0000-0001-9114-8737, Wikipedia:Epithelium]
comment: Editor note: surface epithelium may contain non-epithelial cells, such as melanocytes, lymphocytes and dendritic cells, within the sheet of epithelial cells. Do we consider these part of the epithelium, or located-in it?
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "epithelial tissue" EXACT []
synonym: "portion of epithelium" EXACT [FMA:9639]
xref: AAO:0000144
xref: AAO:0010055
xref: AEO:0000066
xref: BILA:0000066
xref: BTO:0000416
xref: CALOHA:TS-0288
xref: CARO:0000066
xref: EHDAA2:0003066
xref: EMAPA:32738
xref: FBbt:00007005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:9639
xref: GAID:402
xref: HAO:0000066
xref: MA:0003060
xref: MESH:D004848
xref: NCIT:C12710
xref: SCTID:31610004
xref: TAO:0001486
xref: UMLS:C0014609 {source="ncithesaurus:Epithelium"}
xref: VHOG:0000387
xref: Wikipedia:Epithelium
xref: XAO:0003045
xref: ZFA:0001486
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000479 ! tissue
intersection_of: UBERON:0000479 ! tissue
intersection_of: composed_primarily_of CL:0000066 ! epithelial cell
union_of: UBERON:0000486 ! multilaminar epithelium
union_of: UBERON:0000490 ! unilaminar epithelium
relationship: composed_primarily_of CL:0000066 ! epithelial cell
relationship: has_part GO:0005911 ! cell-cell junction
relationship: has_part UBERON:0005769 ! basement membrane of epithelium
relationship: only_in_taxon NCBITaxon:33208 {source="http://palaeos.com/metazoa/porifera/homoscleromorpha.html"} ! Metazoa
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg" xsd:anyURI
property_value: UBPROP:0000003 "The two basic types of metazoan tissue are epithelial and connective. The simplest metazoans, and developmental stages of many primitive invertebrates, consist solely of these two layers. Thus, epithelial and connective tissues may be the primary (original) tissues of metazoans, and both are important in the functional organization of animals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000387", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "epithelial" xsd:string

[Term]
id: UBERON:0000484
name: simple cuboidal epithelium
namespace: uberon
def: "Unilaminar epithelium that consists of a single layer of cuboidal cells." [http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_cuboidal_epithelium]
subset: uberon_slim
subset: vertebrate_core
synonym: "epithelium simplex cuboideum" EXACT []
synonym: "simple cuboidal epithelia" RELATED OMO:0003004 [ZFA:0001497]
xref: AAO:0010064
xref: AEO:0000067
xref: BILA:0000067
xref: CARO:0000067
xref: EHDAA2:0003067
xref: FMA:45566
xref: HAO:0000067
xref: NCIT:C33553
xref: TAO:0001497
xref: UMLS:C0836134 {source="ncithesaurus:Simple_Cuboidal_Epithelium"}
xref: Wikipedia:Simple_cuboidal_epithelium
xref: XAO:0004009
xref: ZFA:0001497
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0010077 ! cuboidal epithelium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d0/Gray1133.png" xsd:anyURI
property_value: editor_note "needs to be synchronized with CL - there is no distinct cuboidal cell in CL" xsd:string

[Term]
id: UBERON:0000485
name: simple columnar epithelium
namespace: uberon
def: "Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]." [FMA:FMA, http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_columnar_epithelium]
subset: uberon_slim
subset: vertebrate_core
synonym: "columnar epithelium" BROAD [EHDAA2:0003068]
synonym: "columnar epithlium" BROAD [AEO:0000068]
synonym: "epithelium simplex columnare" EXACT []
synonym: "simple columnar epithelia" RELATED OMO:0003004 [ZFA:0001496]
synonym: "simple columnar epithelium" EXACT []
xref: AAO:0010063
xref: AEO:0000068
xref: BILA:0000068
xref: CARO:0000068
xref: EHDAA2_RETIRED:0003068
xref: FBbt:00007027 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:45567
xref: HAO:0000068
xref: NCIT:C33552
xref: SCTID:32210007
xref: TAO:0001496
xref: UMLS:C0836135 {source="ncithesaurus:Simple_Columnar_Epithelium"}
xref: Wikipedia:Simple_columnar_epithelium
xref: XAO:0004008
xref: ZFA:0001496
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0012274 ! columnar epithelium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray1059.png" xsd:anyURI

[Term]
id: UBERON:0000486
name: multilaminar epithelium
namespace: uberon
def: "Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA]." [FMA:FMA, http://orcid.org/0000-0001-9114-8737, Wikipedia:Stratified_epithelium]
subset: uberon_slim
subset: vertebrate_core
synonym: "laminated epithelium" RELATED [BTO:0002074]
synonym: "stratified epithelium" EXACT []
xref: AAO:0010059
xref: AEO:0000069
xref: BILA:0000069
xref: BTO:0002074
xref: CARO:0000069
xref: EHDAA2:0003069
xref: FMA:45562
xref: HAO:0000069
xref: NCIT:C33622
xref: SCTID:309044005
xref: TAO:0001494
xref: UMLS:C0682575 {source="ncithesaurus:Stratified_Epithelium"}
xref: Wikipedia:Stratified_epithelium
xref: XAO:0004006
xref: ZFA:0001494
is_a: UBERON:0000483 ! epithelium
property_value: UBPROP:0000001 "Epithelium that consists of more than one layer of epithelial cells.[CARO]" xsd:string {date_retrieved="2012-06-20", external_class="CARO:0000069", ontology="CARO", source="FMA:45562", source="http://orcid.org/0000-0001-9114-8737"}

[Term]
id: UBERON:0000487
name: simple squamous epithelium
namespace: uberon
def: "Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA]." [FMA:45565, http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_squamous_epithelium]
subset: uberon_slim
subset: vertebrate_core
synonym: "epithelium simplex squamosum" EXACT []
synonym: "simple squamous epithelia" RELATED OMO:0003004 [ZFA:0001498]
xref: AAO:0010066
xref: AEO:0000070
xref: BILA:0000070
xref: BTO:0002073
xref: CARO:0000070
xref: EHDAA2:0003070
xref: FMA:45565
xref: HAO:0000070
xref: NCIT:C13178
xref: TAO:0001498
xref: UMLS:C0836133 {source="ncithesaurus:Simple_Squamous_Epithelium"}
xref: Wikipedia:Simple_squamous_epithelium
xref: XAO:0004010
xref: ZFA:0001498
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0006914 ! squamous epithelium
intersection_of: UBERON:0000490 ! unilaminar epithelium
intersection_of: has_part CL:0000076 ! squamous epithelial cell
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg" xsd:anyURI
property_value: UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of squamous cells.[CARO]" xsd:string {date_retrieved="2012-06-20", external_class="CARO:0000070", ontology="CARO", source="FMA:45565", source="http://orcid.org/0000-0001-9114-8737"}

[Term]
id: UBERON:0000488
name: atypical epithelium
namespace: uberon
def: "Epithelium that consists of epithelial cells not arranged in one ore more layers." [http://orcid.org/0000-0001-9114-8737]
subset: vertebrate_core
synonym: "atypical epithelia" RELATED OMO:0003004 [ZFA:0001493]
synonym: "heterogenous epithelium" EXACT []
xref: AAO:0010057
xref: AEO:0000071
xref: BILA:0000071
xref: CARO:0000071
xref: EHDAA2:0003071
xref: FMA:61741
xref: HAO:0000071
xref: TAO:0001493
xref: XAO:0004004
xref: ZFA:0001493
is_a: UBERON:0000483 ! epithelium

[Term]
id: UBERON:0000489
name: cavitated compound organ
namespace: uberon
def: "Compound organ that contains one or more macroscopic anatomical spaces." [http://orcid.org/0000-0001-9114-8737]
subset: organ_slim
subset: upper_level
synonym: "cavitated compound organs" RELATED OMO:0003004 [ZFA:0001490]
synonym: "cavitated organ" EXACT [FMA:55671]
xref: AAO:0010016
xref: AEO:0000072
xref: BILA:0000072
xref: CARO:0000072
xref: EHDAA2:0003072
xref: FMA:55671
xref: HAO:0000072
xref: TAO:0001490
xref: TGMA:0001857
xref: VHOG:0001730
xref: XAO:0003165
xref: ZFA:0001490
is_a: UBERON:0003103 ! compound organ
intersection_of: UBERON:0003103 ! compound organ
intersection_of: has_part UBERON:0002553 ! anatomical cavity
relationship: has_part UBERON:0002553 ! anatomical cavity
property_value: curator_notes "this class was introduced for consistency with CARO, however, it has yet to be used in this or other ontologies. It may be retired in the future" xsd:string

[Term]
id: UBERON:0000490
name: unilaminar epithelium
namespace: uberon
def: "Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA]." [FMA:45561, http://orcid.org/0000-0001-9114-8737]
subset: vertebrate_core
synonym: "simple epithelium" EXACT [FMA:45561]
synonym: "unilaminar epithelia" RELATED OMO:0003004 [ZFA:0001495]
xref: AAO:0010062
xref: AEO:0000073
xref: BILA:0000073
xref: BTO:0002073
xref: CARO:0000073
xref: EHDAA2:0003073
xref: FMA:45561
xref: HAO:0000073
xref: NCIT:C33554
xref: SCTID:309043004
xref: TAO:0001495
xref: UMLS:C0682574 {source="ncithesaurus:Simple_Epithelium"}
xref: XAO:0004007
xref: ZFA:0001495
is_a: UBERON:0000483 ! epithelium
property_value: editor_note "consider adding disjointness axiom between unilaminar and multilaminar - but note that this will render EHDAA2:0003244 (chorionic trophoblast) unsatisfiable" xsd:string
property_value: UBPROP:0000001 "Epithelium that consists of a single layer of epithelial cells.[CARO]" xsd:string {date_retrieved="2012-06-20", external_class="CARO:0000073", ontology="CARO", source="FMA:45561", source="http://orcid.org/0000-0001-9114-8737"}

[Term]
id: UBERON:0000912
name: mucus
namespace: uberon
def: "Mucus is a bodily fluid consisting of a slippery secretion of the lining of the mucous membranes in the body. It is a viscous colloid containing antiseptic enzymes (such as lysozyme) and immunoglobulins. Mucus is produced by goblet cells in the mucous membranes that cover the surfaces of the membranes. It is made up of mucins and inorganic salts suspended in water." [Wikipedia:Mucus]
xref: CALOHA:TS-2144
xref: ENVO:02000040
xref: FMA:66938
xref: GAID:1164
xref: galen:Mucus
xref: MESH:D009093
xref: NCIT:C13259
xref: UMLS:C0026727 {source="ncithesaurus:Mucus"}
xref: Wikipedia:Mucus
is_a: UBERON:0000456 ! secretion of exocrine gland
is_a: UBERON:0006314 ! bodily fluid
relationship: has_part CHEBI:37395 ! mucopolysaccharide
relationship: has_quality PATO:0000998 ! viscous
relationship: produced_by UBERON:0000344 ! mucosa
property_value: UBPROP:0000007 "mucoid" xsd:string
property_value: UBPROP:0000007 "mucous" xsd:string

[Term]
id: UBERON:0000915
name: thoracic segment of trunk
namespace: uberon
def: "Subdivision of trunk that lies between the head and the abdomen." [http://orcid.org/0000-0002-6601-2165]
subset: uberon_slim
synonym: "anterior subdivision of trunk" RELATED []
synonym: "thorax" EXACT [MA:0000022]
synonym: "upper body" RELATED []
synonym: "upper trunk" RELATED [FMA:259209]
xref: EMAPA:35862
xref: FMA:259209
xref: MA:0000022
xref: SCTID:302551006
xref: Wikipedia:Thorax
is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk
is_a: UBERON:0011676 ! subdivision of organism along main body axis
intersection_of: UBERON:0011676 ! subdivision of organism along main body axis
intersection_of: has_skeleton UBERON:0014477 ! thoracic skeleton
relationship: has_skeleton UBERON:0014477 ! thoracic skeleton
property_value: curator_notes "note that we use the slightly verbose term 'thoracic segment of trunk' to avoid confusuon with insect thorax. todo - taxonomic constraints. Also, in FMA 'thorax' is a synonym for chest" xsd:string
property_value: RO:0002171 UBERON:0000026
property_value: RO:0002171 UBERON:0000033
property_value: RO:0002171 UBERON:0002417

[Term]
id: UBERON:0000916
name: abdomen
namespace: uberon
def: "The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "abdominopelvic region" EXACT [FMA:9577]
synonym: "abdominopelvis" EXACT [FMA:9577]
synonym: "adult abdomen" RELATED []
synonym: "belly" RELATED []
synonym: "celiac region" RELATED []
xref: BTO:0000020
xref: CALOHA:TS-0001
xref: EFO:0000968
xref: EMAPA:35102
xref: EV:0100011
xref: FMA:9577
xref: GAID:16
xref: galen:Abdomen
xref: MA:0000029
xref: MAT:0000298
xref: MESH:D000005
xref: MIAA:0000298
xref: SCTID:302553009
xref: Wikipedia:Abdomen
is_a: UBERON:0009569 ! subdivision of trunk
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0002417 {source="MA"} ! abdominal segment of trunk
property_value: editor_note "Vertebrate specific. In arthropods 'abdomen' is the most distal section of the body which lies behind the thorax or cephalothorax. If need be we can introduce some grouping class" xsd:string
property_value: UBPROP:0000007 "abdominal" xsd:string
property_value: UBPROP:0000007 "celiac" xsd:string

[Term]
id: UBERON:0000922
name: embryo
namespace: uberon
def: "Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [BTO:0000379, FB:FBrf0039741, FB:FBrf0041814, GO:0009790, Wikipedia:Embryo]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "developing organism" RELATED [BILA:0000056]
synonym: "developmental tissue" RELATED []
synonym: "embryonic organism" EXACT [BILA:0000056]
xref: AAO:0011035
xref: AEO:0000169
xref: BILA:0000056
xref: BSA:0000039
xref: BTO:0000379
xref: CALOHA:TS-0229
xref: EFO:0001367
xref: EHDAA2:0000002
xref: EHDAA2_RETIRED:0003236
xref: EHDAA:38
xref: EMAPA:16039
xref: FBbt:00000052 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:69068
xref: GAID:963
xref: http://neurolex.org/wiki/Category\:Embryonic_organism
xref: IDOMAL:0000646 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: MAT:0000226
xref: MESH:D004622
xref: MIAA:0000019
xref: NCIT:C28147
xref: OGEM:000001
xref: SCTID:57991002
xref: UMLS:C0013935 {source="ncithesaurus:Embryo"}
xref: VHOG:0001766
xref: Wikipedia:Embryo
xref: XAO:0000113
xref: ZFA:0000103
is_a: UBERON:0000468 ! multicellular organism
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: existence_ends_with UBERON:0000068 ! embryo stage
intersection_of: existence_starts_with UBERON:0000068 ! embryo stage
relationship: existence_ends_with UBERON:0000068 ! embryo stage
relationship: existence_starts_with UBERON:0000068 ! embryo stage
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/2/2d/Wrinkledfrog_embryos.jpg" xsd:anyURI
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/503" xsd:anyURI
property_value: UBPROP:0000007 "embryonic" xsd:string
property_value: UBPROP:0000012 "Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo" xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0000923
name: germ layer
namespace: uberon
def: "A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm." [https://github.com/obophenotype/uberon/issues/203, Wikipedia:Germ_layer]
comment: Classically the germ layers are ectoderm, mesoderm and endoderm. Alternatively: primary = ectoderm, endoderm; secondary=mesoderm; tertiary=dorsal mesoderm, NC[https://github.com/obophenotype/uberon/wiki/The-neural-crest]
subset: uberon_slim
subset: vertebrate_core
synonym: "embryonic germ layer" RELATED []
synonym: "embryonic germ layers" RELATED []
synonym: "embryonic tissue" BROAD [FMA:69069]
synonym: "germinal layer" EXACT [ncithesaurus:Germinal_Layer]
synonym: "primary germ layer" NARROW [GO:0001704, ZFA:0001122]
xref: AAO:0000480
xref: BILA:0000035
xref: BTO:0000556
xref: EMAPA:36033
xref: FBbt:00000110 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:69069
xref: GAID:1303
xref: MESH:D005855
xref: NCIT:C12950
xref: NCIT:C54105
xref: TAO:0001122
xref: UMLS:C0920502 {source="ncithesaurus:Embryonic_Tissue"}
xref: UMLS:C1708239 {source="ncithesaurus:Germinal_Layer"}
xref: VHOG:0001223
xref: Wikipedia:Germ_layer
xref: XAO:0003011
xref: ZFA:0001122
is_a: UBERON:0010316 ! germ layer / neural crest
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001223", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000924
name: ectoderm
namespace: uberon
def: "Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue." [Wikipedia:Ectoderm]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "embryonic ectoderm" EXACT [VHOG:0000153]
xref: AAO:0000137
xref: BILA:0000036
xref: BTO:0000315
xref: CALOHA:TS-0216
xref: EFO:0000414
xref: EHDAA2:0000428
xref: EMAPA:16069
xref: EV:0100003
xref: FBbt:00000111 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:69070
xref: GAID:1304
xref: MAT:0000155
xref: MAT:0000173
xref: MESH:D004475
xref: MIAA:0000173
xref: NCIT:C12703
xref: SCTID:362851007
xref: TAO:0000016
xref: UMLS:C0013574 {source="ncithesaurus:Ectoderm"}
xref: VHOG:0000153
xref: Wikipedia:Ectoderm
xref: XAO:0000001
xref: ZFA:0000016
is_a: UBERON:0000923 ! germ layer
relationship: develops_from UBERON:0006601 ! presumptive ectoderm
relationship: has_part CL:0000221 ! ectodermal cell
relationship: immediate_transformation_of UBERON:0006601 {source="Bgee:AN"} ! presumptive ectoderm
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png" xsd:anyURI
property_value: UBPROP:0000001 "Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000137", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000153", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "ectodermal" xsd:string

[Term]
id: UBERON:0000925
name: endoderm
namespace: uberon
def: "Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut." [Wikipedia:Endoderm]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "entoderm" RELATED DEPRECATED [DOI:10.5962/bhl.title.1013]
xref: AAO:0000139
xref: BILA:0000038
xref: BTO:0000800
xref: CALOHA:TS-0273
xref: EFO:0002545
xref: EHDAA2:0000436
xref: EMAPA:16062
xref: EV:0100005
xref: FBbt:00000125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:69071
xref: GAID:1305
xref: MAT:0000175
xref: MESH:D004707
xref: MIAA:0000175
xref: NCIT:C12706
xref: SCTID:362855003
xref: TAO:0000017
xref: UMLS:C0014144 {source="ncithesaurus:Endoderm"}
xref: VHOG:0000154
xref: Wikipedia:Endoderm
xref: XAO:0000090
xref: ZFA:0000017
is_a: UBERON:0000923 ! germ layer
relationship: develops_from UBERON:0006595 ! presumptive endoderm
relationship: has_part CL:0000223 ! endodermal cell
relationship: immediate_transformation_of UBERON:0006595 {source="Bgee:AN"} ! presumptive endoderm
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png" xsd:anyURI
property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000154", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "endodermal" xsd:string

[Term]
id: UBERON:0000926
name: mesoderm
namespace: uberon
alt_id: UBERON:0003263
def: "The middle germ layer of the embryo, between the endoderm and ectoderm." [Wikipedia:Mesoderm]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "embryonic mesoderm" RELATED [VHOG:0000152]
synonym: "entire mesoderm" RELATED [https://orcid.org/0000-0002-6601-2165, SCTID:362854004]
synonym: "mesodermal mantle" RELATED []
xref: AAO:0000304
xref: BILA:0000037
xref: BTO:0000839
xref: CALOHA:TS-0623
xref: EFO:0001981
xref: EHDAA2:0001128
xref: EHDAA:124
xref: EHDAA:160
xref: EHDAA:183
xref: EMAPA:16083
xref: EV:0100006
xref: FBbt:00000126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:69072
xref: GAID:522
xref: MAT:0000174
xref: MESH:D008648
xref: MIAA:0000174
xref: NCIT:C12750
xref: SCTID:362854004
xref: TAO:0000041
xref: UMLS:C0025485 {source="ncithesaurus:Mesoderm"}
xref: VHOG:0000152
xref: Wikipedia:Mesoderm
xref: XAO:0000050
xref: ZFA:0000041
is_a: UBERON:0000923 {notes="sometimes not considered primary"} ! germ layer
relationship: develops_from UBERON:0006603 ! presumptive mesoderm
relationship: has_part CL:0000222 ! mesodermal cell
relationship: immediate_transformation_of UBERON:0006603 {source="Bgee:AN"} ! presumptive mesoderm
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png" xsd:anyURI
property_value: RO:0002161 NCBITaxon:6040
property_value: UBPROP:0000001 "Primary germ layer that is the middle of the embryonic germ layers.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000304", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000152", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "mesodermal" xsd:string
property_value: UBPROP:0000008 "sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates" xsd:string {source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"}

[Term]
id: UBERON:0000930
name: stomodeum
namespace: uberon
def: "Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/326, Wikipedia:Stomodeum]
subset: grouping_class
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "mouth pit" RELATED [EMAPA:16263]
synonym: "mouth primordium" EXACT [XAO:0000269]
synonym: "oral ectoderm" RELATED [ZFA:0001290, ZFIN:ZDB-PUB-100726-23]
synonym: "oral pit" RELATED [EMAPA:16263]
synonym: "primitive oral cavity" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "stomatodeum" EXACT [Wikipedia:Stomodeum]
synonym: "stomodaeum" EXACT []
synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269]
xref: BTO:0004224
xref: EHDAA2:0001929
xref: EMAPA:16263
xref: FBbt:00000439 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:295846
xref: NCIT:C34306
xref: TAO:0001290
xref: TGMA:0000135
xref: UMLS:C1514977 {source="ncithesaurus:Stomodeum"}
xref: Wikipedia:Stomodeum
xref: XAO:0000269
xref: ZFA:0001290
is_a: UBERON:0013522 ! subdivision of tube
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000924 ! ectoderm
relationship: part_of UBERON:0035804 ! future mouth
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/93/Gray977.png" xsd:anyURI
property_value: editor_note "consider indicating location. e.g. anterior. Note some AOs place this as part of oral opening, but it's not clear when this structure comes into existence" xsd:string
property_value: UBPROP:0000001 "Anterior part of the embryonic alimentary canal formed as an invagination of the ectoderm; the future mouth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001290", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "the primordial mouth region of the developing head, initially a midline ectodermal depression between the forebrain bulge (cranially) and the heart bulge (caudally) and between the maxillary and mandibular components of the first pharyngeal arch; the stomodeum is separated from the anterior end of the foregut by the buccopharyngeal membrane; the mouth is developed partly from the stomodeum, and partly from the floor of the anterior portion of the foregut; the lips, teeth, and gums are formed from the walls of the stomodeum, but the tongue is developed in the floor of the pharynx" xsd:string {source="MP:0012522", taxon="NCBITaxon:40674"}
property_value: UBPROP:0000007 "stomodeal" xsd:string
property_value: UBPROP:0000008 "This class groups together disparate structures as all being the anterior part of the early metazoan digestive tract and precursor of the mouth. However, the developmental processes vary, so this class may be split in future. E.g. in mammals it is a rostral depression surrounded by prominences. Outgrowth of the prominences produces a stomodeal cavity." xsd:string

[Term]
id: UBERON:0000931
name: proctodeum
namespace: uberon
def: "Inward fold on the surface of the embryonic ectoderm that develops into an ectodermal terminal part of the digestive tract." [https://github.com/obophenotype/uberon/issues/685, https://sourceforge.net/p/fbbtdv/tickets/52, ZFA:0000066]
subset: uberon_slim
synonym: "amnioproctodeal invagination" NARROW [FBbt:00000123]
synonym: "anal pit" RELATED [VHOG:0000139]
synonym: "anus porus" RELATED [XAO:0001019]
synonym: "embryonic proctodaeum" EXACT []
synonym: "proctodaeum" EXACT []
xref: AAO:0011087
xref: EHDAA2:0000121
xref: EMAPA:25038
xref: FBbt:00000123 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: NCIT:C34278
xref: TAO:0000066
xref: UMLS:C0231054 {source="ncithesaurus:Proctodeum"}
xref: VHOG:0000139
xref: Wikipedia:Proctodeum
xref: XAO:0001019
xref: ZFA:0000066
is_a: UBERON:0016566 {source="EHDAA2"} ! pit
relationship: develops_from UBERON:0000924 ! ectoderm
relationship: has_potential_to_develop_into UBERON:0001353 ! anal region
relationship: located_in UBERON:0012469 {source="EHDAA2"} ! external anal region
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0007026 ! presumptive gut
property_value: editor_note "removed WBbt:0006795 'proctodeum' - junction between the alimentary and genital tracts in the male." xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/ANiknejad
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/dosumis
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/mmc46
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/685" xsd:anyURI
property_value: UBPROP:0000001 "An inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000066", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011087", ontology="AAO", source="ZFA:0000066"}
property_value: UBPROP:0000007 "proctodeal" xsd:string

[Term]
id: UBERON:0000945
name: stomach
namespace: uberon
def: "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." [https://orcid.org/0000-0002-6601-2165, ISBN:0073040584, Wikipedia:Stomach]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "anterior intestine" RELATED []
synonym: "gaster" RELATED [BTO:0001307]
synonym: "mesenteron" RELATED []
synonym: "stomach chamber" NARROW []
synonym: "ventriculus" RELATED OMO:0003011 [Wikipedia:Stomach]
xref: AAO:0000579
xref: ANISEED:1235297
xref: BTO:0001307
xref: CALOHA:TS-0980
xref: EFO:0000837
xref: EHDAA2:0001915
xref: EHDAA:2993
xref: EMAPA:17021
xref: EV:0100070
xref: FMA:7148
xref: GAID:293
xref: galen:Stomach
xref: MA:0000353
xref: MAT:0000051
xref: MESH:D013270
xref: MIAA:0000051
xref: NCIT:C12391
xref: SCTID:181246003
xref: TAO:0002121
xref: UMLS:C0038351 {source="ncithesaurus:Stomach"}
xref: VHOG:0000408
xref: Wikipedia:Stomach
xref: XAO:0000128
is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract
is_a: UBERON:0010039 {source="cjm"} ! food storage organ
relationship: capable_of GO:0001696 {evidence="ISBN:0486692132"} ! gastric acid secretion
relationship: contributes_to_morphology_of UBERON:0001007 ! digestive system
relationship: only_in_taxon NCBITaxon:7776 {notes="absent in lampreys and hagfishes", source="ISBN:0073040584"} ! Gnathostomata <vertebrates>
relationship: part_of UBERON:0001041 ! foregut
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/e/e0/Stomach_diagram.svg" xsd:anyURI
property_value: RO:0002161 NCBITaxon:7864 {source="Wikipedia"}
property_value: RO:0002161 NCBITaxon:7878 {source="Wikipedia"}
property_value: RO:0002161 NCBITaxon:7955 {source="ZFA"}
property_value: RO:0002161 NCBITaxon:9259 {source="Wikipedia"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Portion of alimentary canal with increased circular and longitudinal smooth muscle. Bounded posteriorly by the pyloric sphincter. Mucosal lining has increased folding.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000579", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "It appears that the stomach has an ancient origin. The stomach first appears in the fish lineage. The prevertebrate chordates do not have a true stomach, whereas the cartilaginous and bony fish do. Although most fish do have a true stomach, some fish species appear to have lost the stomach secondarily. The remaining vertebrate lineages do have a true stomach (at least in the adult animal), although there is great variation in the size and shape of the stomach.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000408", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00076.x Smith DM, Grasty RC, Theodosiou NA, Tabin CJ, Nascone-Yoder NM, Evolutionary relationships between the amphibian, avian, and mammalian stomachs. Evolution and development (2000)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "We restrict this to the vertebrate specific structure - see the grouping class 'food storage organ' for analogous structures in other species. Teleosts: Zebrafish is functionally stomach-less, but may retain ontogenic footprint. Although the precise shape and size of the stomach varies widely among different vertebrates, the relative positions of the oesophageal and duodenal openings remain relatively constant. As a result, the organ always curves somewhat to the left before curving back to meet the pyloric sphincter. However, lampreys, hagfishes, chimaeras, lungfishes, and some teleost fish have no stomach at all, with the oesophagus opening directly into the intestine. The gastric lining is usually divided into two regions, an anterior portion lined by fundic glands, and a posterior with pyloric glands. Cardiac glands are unique to mammals, and even then are absent in a number of species. The distributions of these glands vary between species, and do not always correspond with the same regions as in man. Furthermore, in many non-human mammals, a portion of the stomach anterior to the cardiac glands is lined with epithelium essentially identical to that of the oesophagus. Ruminants, in particular, have a complex stomach, the first three chambers of which are all lined with oesophageal mucosa" xsd:string {source="WP:Stomach#In_other_animals"}

[Term]
id: UBERON:0000947
name: aorta
namespace: uberon
def: "The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MESH:A07.231.114.056, MP:0000272, Wikipedia:Aorta]
subset: efo_slim
subset: grouping_class
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "arteria maxima" RELATED OMO:0003011 [Wikipedia:Aorta]
synonym: "dorsal aorta" NARROW SENSU [Wikipedia:Aorta#In_other_animals, ZFA:0000014]
synonym: "trunk of aortic tree" EXACT []
synonym: "trunk of systemic arterial tree" EXACT []
xref: AAO:0010213
xref: BTO:0000135
xref: CALOHA:TS-0046
xref: EFO:0000265
xref: EMAPA:18601
xref: EV:0100027
xref: FMA:3734
xref: GAID:469
xref: galen:Aorta
xref: MA:0000062
xref: MAT:0000035
xref: MESH:D001011
xref: MIAA:0000035
xref: NCIT:C12669
xref: SCTID:181298001
xref: UMLS:C0003483 {source="ncithesaurus:Aorta"}
xref: VHOG:0001523
xref: Wikipedia:Aorta
xref: XAO:0003010
is_a: UBERON:0003509 {source="MA"} ! arterial blood vessel
is_a: UBERON:0003519 ! thoracic cavity blood vessel
is_a: UBERON:0013768 ! great vessel of heart
relationship: connected_to UBERON:0002084 ! heart left ventricle
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0010191 {source="EHDAA2"} ! aortic system
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/9/91/Aorta_scheme.jpg" xsd:anyURI
property_value: editor_note "This class is currently a mixed bag, encompassing (1) the entirety of the mammalian aorta together with (2) the developmental and phylogenetic homologs of its segments: the ventral aorta and dorsal aortae." xsd:string {source="WP"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The main artery of the circulatory system which carries oxygenated blood from the heart to all the arteries of the body except those of the lungs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010213", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001523", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "aortic" xsd:string
property_value: UBPROP:0000008 "All amniotes have a broadly similar arrangement to that of humans, albeit with a number of individual variations. In fish, however, there are two separate vessels referred to as aortas. The ventral aorta carries de-oxygenated blood from the heart to the gills; part of this vessel forms the ascending aorta in tetrapods (the remainder forms the pulmonary artery). A second, dorsal aorta carries oxygenated blood from the gills to the rest of the body, and is homologous with the descending aorta of tetrapods. The two aortas are connected by a number of vessels, one passing through each of the gills. Amphibians also retain the fifth connecting vessel, so that the aorta has two parallel arches" xsd:string

[Term]
id: UBERON:0000948
name: heart
namespace: uberon
def: "A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Heart]
comment: Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "branchial heart" NARROW SENSU []
synonym: "cardium" RELATED [EMAPA:16105]
synonym: "chambered heart" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "vertebrate heart" EXACT []
xref: AAO:0010210
xref: BILA:0000020
xref: BTO:0000562
xref: CALOHA:TS-0445
xref: EFO:0000815
xref: EHDAA2:0000738
xref: EHDAA:420
xref: EMAPA:16105
xref: EV:0100018
xref: FMA:7088
xref: GAID:174
xref: galen:Heart
xref: MA:0000072
xref: MAT:0000036
xref: MESH:D006321
xref: MIAA:0000036
xref: NCIT:C12727
xref: SCTID:302509004
xref: TAO:0000114
xref: UMLS:C0018787 {source="ncithesaurus:Heart"}
xref: VHOG:0000276
xref: Wikipedia:Heart
xref: XAO:0000064
xref: ZFA:0000114
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005181 ! thoracic segment organ
is_a: UBERON:0007100 ! primary circulatory organ
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
intersection_of: UBERON:0007100 ! primary circulatory organ
intersection_of: has_part UBERON:0004151 ! cardiac chamber
relationship: contributes_to_morphology_of UBERON:0004535 ! cardiovascular system
relationship: develops_from UBERON:0004141 ! heart tube
relationship: has_part UBERON:0004151 ! cardiac chamber
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0015410 {source="MA"} ! heart plus pericardium
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Heart.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI
property_value: RO:0002161 NCBITaxon:6239
property_value: RO:0002161 NCBITaxon:7227
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000114", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010210", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000002 "relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010210", ontology="AAO"}
property_value: UBPROP:0000003 "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000276", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "cardiac" xsd:string

[Term]
id: UBERON:0000949
name: endocrine system
namespace: uberon
def: "Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity." [NLM:endocrine+system, Wikipedia:Endocrine_system]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "endocrine glandular system" EXACT [EHDAA2:0002224]
synonym: "endocrine system" EXACT []
synonym: "systema endocrinum" EXACT []
xref: AAO:0010279
xref: CALOHA:TS-1301
xref: EFO:0002969
xref: EHDAA2:0002224
xref: EMAPA:35306
xref: EV:0100128
xref: FBbt:00005068 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:9668
xref: GAID:439
xref: MA:0000012
xref: MESH:D004703
xref: NCIT:C12705
xref: SCTID:278876000
xref: TAO:0001158
xref: UMLS:C0014136 {source="ncithesaurus:Endocrine_System"}
xref: VHOG:0000098
xref: Wikipedia:Endocrine_system
xref: XAO:0000158
xref: ZFA:0001158
is_a: UBERON:0015204 ! glandular system
disjoint_from: UBERON:0000990 ! reproductive system
disjoint_from: UBERON:0001004 ! respiratory system
disjoint_from: UBERON:0001007 ! digestive system
disjoint_from: UBERON:0001009 ! circulatory system
disjoint_from: UBERON:0001016 ! nervous system
disjoint_from: UBERON:0001434 ! skeletal system
disjoint_from: UBERON:0002204 ! musculoskeletal system
disjoint_from: UBERON:0002294 ! biliary system
disjoint_from: UBERON:0002330 ! exocrine system
disjoint_from: UBERON:0002390 ! hematopoietic system
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: composed_primarily_of UBERON:0002368 ! endocrine gland
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: UBPROP:0000001 "Anatomical system containing glands which regulates bodily functions though the secretion of hormones.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010279", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "Multicellular organisms have complex endocrine systems, allowing responses to environmental stimuli, regulation of development, reproduction, and homeostasis. Nuclear receptors (NRs), a metazoan-specific family of ligand-activated transcription factors, play central roles in endocrine responses, as intermediates between signaling molecules and target genes. The NR family includes ligand-bound and orphan receptors, that is, receptors with no known ligand or for which there is no ligand Pocket. Understanding NR evolution has been further improved by comparison of several completed genomes, particularly those of deuterostomes and ecdysozoans. In contrast, evolution of NR ligands is still much debated. One hypothesis proposes that several independent gains and losses of ligand-binding ability in NRs occurred in protostomes and deuterostomes. A second hypothesis, pertaining to the NR3 subfamily (vertebrate steroid hormone receptors and estrogen related receptor), proposes that before the divergence of protostomes and deuterostomes, there was an ancestral steroid receptor (AncSR) that was ligand-activated and that orphan receptors secondarily lost the ability to bind a ligand. (...) Our analysis reveals that steroidogenesis has been independently elaborated in the 3 main bilaterian lineages (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000098", ontology="VHOG", source="DOI:10.1073/pnas.0812138106 Markov GV, Tavares R, Dauphin-Villemant C, Demeneix BA, Baker ME, Laudet V, Independent elaboration of steroid hormone signaling pathways in metazoans. PNAS (2009)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "endocrine" xsd:string

[Term]
id: UBERON:0000955
name: brain
namespace: uberon
def: "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Brain]
subset: cumbo
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "encephalon" RELATED [BTO:0000142]
synonym: "suprasegmental levels of nervous system" RELATED [NeuroNames:21]
synonym: "suprasegmental structures" RELATED [NeuroNames:21]
synonym: "synganglion" RELATED []
synonym: "the brain" RELATED [NeuroNames:21]
xref: AAO:0010478
xref: ABA:Brain
xref: BAMS:Br
xref: BAMS:Brain
xref: BILA:0000135
xref: BIRNLEX:796
xref: BTO:0000142
xref: CALOHA:TS-0095
xref: DHBA:10155
xref: EFO:0000302
xref: EHDAA2:0000183
xref: EHDAA:2641
xref: EHDAA:6485
xref: EMAPA:16894
xref: EV:0100164
xref: FBbt:00005095 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:50801
xref: GAID:571
xref: galen:Brain
xref: HBA:4005
xref: MA:0000168
xref: MAT:0000098
xref: MBA:8
xref: MBA:997
xref: MESH:D001921
xref: MIAA:0000098
xref: NCIT:C12439
xref: neuronames:21 {source="BIRNLEX:796"}
xref: PBA:3999
xref: SCTID:258335003
xref: TAO:0000008
xref: UMLS:C0006104 {source="ncithesaurus:Brain", source="BIRNLEX:796"}
xref: UMLS:C1269537 {source="BIRNLEX:796"}
xref: VHOG:0000157
xref: Wikipedia:Brain
xref: XAO:0000010
xref: ZFA:0000008
is_a: UBERON:0000062 {source="GO"} ! organ
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: capable_of GO:0050890 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! cognition
relationship: composed_primarily_of CL:0002319 ! neural cell
relationship: contributes_to_morphology_of UBERON:0001016 ! nervous system
relationship: develops_from UBERON:0001049 {gci_relation="part_of", gci_filler="NCBITaxon:7711"} ! neural tube
relationship: develops_from UBERON:0006238 ! future brain
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: immediate_transformation_of UBERON:0006238 {source="Bgee:AN"} ! future brain
relationship: in_anterior_side_of UBERON:0000468 ! multicellular organism
relationship: part_of UBERON:0001017 {source="FMA"} ! central nervous system
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_F_Brain.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_M_Brain.glb" xsd:anyURI
property_value: editor_note "requires review for applicability to invertebrate structures, e.g. synganglion" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000008", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Part of the central nervous system situated within the cranium and composed of both nerve cell bodies and nerve fibers.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010478", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The part of the central nervous system contained within the cranium, comprising the forebrain, midbrain, hindbrain, and metencephalon. It is derived from the anterior part of the embryonic neural tube (or the encephalon). Does not include retina. (CUMBO)" xsd:string {source="http://neurolex.org/wiki/Cumbo_terms"}
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000157", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000957
name: lamina
namespace: uberon
def: "Any thin layer or plate." [Wikipedia:Lamina_of_the_vertebral_arch]
subset: non_informative
subset: uberon_slim
subset: upper_level
synonym: "laminar tissue" EXACT []
xref: Wikipedia:Lamina_of_the_vertebral_arch
is_a: UBERON:0000479 ! tissue
intersection_of: UBERON:0000479 ! tissue
intersection_of: has_quality PATO:0002124 ! laminar
relationship: has_quality PATO:0002124 ! laminar
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/80/Laminaarcusvertebrae.png" xsd:anyURI
property_value: editor_note "TODO - merge with cell layer?" xsd:string
property_value: UBPROP:0000007 "laminar" xsd:string

[Term]
id: UBERON:0000962
name: nerve of cervical vertebra
namespace: uberon
def: "The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]." [Wikipedia:Cervical_nerves]
comment: Innervates: sternohyoid muscle, sternothyroid muscle, omohyoid muscle[WP]
subset: uberon_slim
synonym: "cervical nerve" EXACT [FMA:5859]
synonym: "cervical nerve tree" EXACT []
synonym: "cervical spinal nerve" EXACT []
synonym: "nervus cervicalis" EXACT OMO:0003011 [FMA:5859, FMA:TA]
xref: BAMS:cern
xref: FMA:5859
xref: NCIT:C32299
xref: neuronames:2351
xref: NLXANAT:20090207
xref: SCTID:360497008
xref: UMLS:C0228815 {source="ncithesaurus:Cervical_Nerve"}
xref: Wikipedia:Cervical_nerves
is_a: UBERON:0001780 ! spinal nerve
intersection_of: UBERON:0001780 ! spinal nerve
intersection_of: extends_fibers_into UBERON:0002726 ! cervical spinal cord
relationship: extends_fibers_into UBERON:0002726 ! cervical spinal cord
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray795.png" xsd:anyURI

[Term]
id: UBERON:0000963
name: head sensillum
namespace: uberon
xref: FBbt:00004114 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: MAT:0000204
xref: MIAA:0000204
is_a: UBERON:0002536 ! arthropod sensillum
intersection_of: UBERON:0002536 ! arthropod sensillum
intersection_of: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0000033 ! head
property_value: editor_note "this term should be ceded to the arthropod anatomy ontology" xsd:string

[Term]
id: UBERON:0000964
name: cornea
namespace: uberon
def: "The transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure." [ISBN:0-683-40008-8, MESH:A09.371.060.217, MP:0001312]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cornea of camera-type eye" EXACT [GO:0061303]
synonym: "corneas" RELATED OMO:0003004 [ZFA:0000640]
synonym: "tunica cornea" RELATED []
xref: AAO:0010344
xref: BTO:0000286
xref: CALOHA:TS-0171
xref: EFO:0000377
xref: EHDAA2:0000316
xref: EHDAA:10199
xref: EMAPA:17161
xref: EV:0100341
xref: FMA:58238
xref: GAID:892
xref: MA:0000266
xref: MESH:D003315
xref: NCIT:C12342
xref: SCTID:181162001
xref: TAO:0000640
xref: UMLS:C0010031 {source="ncithesaurus:Cornea"}
xref: VHOG:0000164
xref: Wikipedia:Cornea
xref: XAO:0000180
xref: ZFA:0000640
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0010000 ! multicellular anatomical structure
is_a: UBERON:0010313 ! neural crest-derived structure
relationship: continuous_with UBERON:0001773 ! sclera
relationship: contributes_to_morphology_of UBERON:0001801 ! anterior segment of eyeball
relationship: developmentally_induced_by UBERON:0005426 ! lens vesicle
relationship: develops_from UBERON:0004348 {evidence="definitional"} ! optic eminence
relationship: develops_from UBERON:0005427 ! corneal primordium
relationship: has_part UBERON:0001772 ! corneal epithelium
relationship: has_part UBERON:0004370 ! anterior limiting lamina of cornea
relationship: has_quality PATO:0000964 ! transparent
relationship: part_of UBERON:0001801 {source="MA"} ! anterior segment of eyeball
relationship: part_of UBERON:0010409 {source="MA"} ! ocular surface region
relationship: part_of UBERON:0012430 {source="FMA-isa"} ! tunica fibrosa of eyeball
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000007 "corneal" xsd:string
property_value: UBPROP:0000008 "Compared to terrestial animals, the cornea of zebrafish is relatively flat. It consists of nonpigmented, stratified squamous nonkeratinizing epithelial cells, attached to a thick basement membrane that is considered to be analogous to the Bowman's membrane in mammals. In fish, and aquatic vertebrates in general, the cornea plays no role in focusing light, since it has virtually the same refractive index as water" xsd:string

[Term]
id: UBERON:0000965
name: lens of camera-type eye
namespace: uberon
def: "A transparent and refractive lens located posterior to the iris. The lens of camera-type eye refracts light to be focused on the retina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Lens_(anatomy)]
comment: The lens is avascular and nourished by diffusion from the aqueous and vitreous humors.
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "camera-type eye lens" EXACT [GO:0002088]
synonym: "crystalline lens" RELATED [BTO:0000723, PMID:36055924]
synonym: "eye lens" EXACT SENSU []
synonym: "lens" EXACT SENSU []
synonym: "lens crystallina" EXACT [Wikipedia:Lens_(anatomy)]
synonym: "lenses" RELATED OMO:0003004 [ZFA:0000035]
synonym: "ocular lens" RELATED [BTO:0000723]
xref: AAO:0010348
xref: BTO:0000723
xref: CALOHA:TS-0545
xref: EHDAA:9057
xref: EMAPA:17838
xref: EV:0100343
xref: FMA:58241
xref: MA:0000275
xref: MAT:0000141
xref: MESH:D007908
xref: MIAA:0000141
xref: NCIT:C12743
xref: RETIRED_EHDAA2:0000975
xref: SCTID:181169005
xref: TAO:0000035
xref: UMLS:C0023317 {source="ncithesaurus:Crystalline_Lens"}
xref: VHOG:0000169
xref: Wikipedia:Lens_(anatomy)
xref: XAO:0000008
xref: ZFA:0000035
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005389 ! transparent eye structure
relationship: contributes_to_morphology_of UBERON:0001801 ! anterior segment of eyeball
relationship: developmentally_induced_by UBERON:0003902 ! retinal neural layer
relationship: develops_from UBERON:0005426 ! lens vesicle
relationship: part_of UBERON:0001801 ! anterior segment of eyeball
property_value: RO:0002171 UBERON:0002049
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000169", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "This class excludes compound eye corneal lenses." xsd:string

[Term]
id: UBERON:0000966
name: retina
namespace: uberon
def: "The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [Wikipedia:Retina, ZFIN:curator]
comment: Currently this class encompasses only verteberate AOs but could in theory also include cephalopod - we may want to make a more specific class for vertebrate retina. note that this class excludes ommatidial retinas, as the retina must be part of an eyeball. Use the parent class photoreceptor array / light-sensitive tissue for arthropods
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "inner layer of eyeball" EXACT []
synonym: "Netzhaut" RELATED [BTO:0001175]
synonym: "retina of camera-type eye" EXACT [GO:0060041]
synonym: "retinas" RELATED OMO:0003004 [ZFA:0000152]
synonym: "tunica interna of eyeball" EXACT []
xref: AAO:0010352
xref: BAMS:R
xref: BIRNLEX:1153
xref: BTO:0001175
xref: CALOHA:TS-0865
xref: EFO:0000832
xref: EHDAA2:0001627
xref: EHDAA:4757
xref: EMAPA:17168
xref: EV:0100348
xref: FMA:58301
xref: GAID:755
xref: MA:0000276
xref: MAT:0000142
xref: MBA:304325711
xref: MESH:D012160
xref: MIAA:0000142
xref: NCIT:C12343
xref: neuronames:1862
xref: NIFSTD_RETIRED:birnlex_1156
xref: SCTID:181171005
xref: TAO:0000152
xref: UMLS:C0035298 {source="BIRNLEX:1153", source="ncithesaurus:Retina"}
xref: UMLS:C1278894 {source="BIRNLEX:1153"}
xref: VHOG:0000229
xref: Wikipedia:Retina
xref: XAO:0000009
xref: ZFA:0000152
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005388 ! photoreceptor array
relationship: develops_from UBERON:0003072 {source="EHDAA2"} ! optic cup
relationship: has_part CL:0000573 {source="FMA"} ! retinal cone cell
relationship: has_part CL:0000604 {source="FMA"} ! retinal rod cell
relationship: has_part CL:0000740 {source="FMA"} ! retinal ganglion cell
relationship: part_of UBERON:0001802 ! posterior segment of eyeball
relationship: part_of UBERON:0019207 ! chorioretinal region
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png" xsd:anyURI
property_value: RO:0002161 NCBITaxon:6656
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The portion of the eye developing from the optic primordium and including the neural retina and the retinal pigment layer. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000152", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000229", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "retinal" xsd:string

[Term]
id: UBERON:0000970
name: eye
namespace: uberon
def: "An organ that detects light." [https://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: functional_classification
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: uberon_slim
synonym: "light-detecting organ" RELATED []
synonym: "visual apparatus" RELATED [EV:0100336]
xref: BILA:0000017
xref: BTO:0000439
xref: CALOHA:TS-0309
xref: EFO:0000827
xref: EV:0100336
xref: FBbt:00005162 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: GAID:69
xref: MAT:0000140
xref: MESH:D005123
xref: MIAA:0000140
xref: Wikipedia:Eye
is_a: UBERON:0000020 ! sense organ
relationship: capable_of GO:0009584 ! detection of visible light
relationship: has_part CL:0000149 {source="PMID:21062451"} ! visual pigment cell
relationship: has_part CL:0000210 {source="PMID:21062451"} ! photoreceptor cell
relationship: part_of UBERON:0002104 ! visual system
property_value: curator_notes "This class encompasses a variety of light-detecting structures from different phyla with no implication of homology, from the compound insect eye to the vertebrate camera-type eye (distinct classes are provided for each)" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000007 "ocular" xsd:string
property_value: UBPROP:0000007 "optic" xsd:string
property_value: UBPROP:0000010 "Note that whilst this is classified as an organ, it is in fact more of a unit composed of different structures: in Drosophila, it includes the interommatidial bristle as a part; we consider here the vertebrate eye to include the eyeball/eye proper as a part, with the eye having as parts (when present): eyelids, conjuctiva," xsd:string

[Term]
id: UBERON:0000971
name: ommatidium
namespace: uberon
def: "The smallest morphological and functional unit of the compound eye that consists of a usually limited and often constant number of rhabdomeric photoreceptor cells, cornea-secreting epithelial cells, and interommatidial pigment cells, and may additionally contain crystalline cone cells." [PMID:21062451]
subset: uberon_slim
synonym: "omatidia" RELATED OMO:0003004 []
synonym: "omatidium" EXACT []
xref: BTO:0001922
xref: FBbt:00004510 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: HAO:0000666
xref: MAT:0000143
xref: MIAA:0000143
xref: Wikipedia:Ommatidium
is_a: UBERON:0000970 {source="PMID:21062451"} ! eye
is_a: UBERON:0002536 ! arthropod sensillum
relationship: part_of UBERON:0000018 ! compound eye
property_value: UBPROP:0000007 "ommatidial" xsd:string

[Term]
id: UBERON:0000974
name: neck
namespace: uberon
def: "An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "collum" RELATED OMO:0003011 [Wikipedia:Neck]
synonym: "neck (volume)" RELATED [FMA:7155]
xref: AEO:0000108
xref: BTO:0000420
xref: CALOHA:TS-2045
xref: EFO:0000967
xref: EHDAA2:0003108
xref: EMAPA:35587
xref: FMA:7155
xref: GAID:86
xref: galen:Neck
xref: MA:0000024
xref: MAT:0000297
xref: MESH:D009333
xref: MIAA:0000297
xref: NCIT:C13063
xref: SCTID:302550007
xref: UMLS:C0027530 {source="ncithesaurus:Neck"}
xref: Wikipedia:Neck
is_a: UBERON:0000475 ! organism subdivision
relationship: anteriorly_connected_to UBERON:0000033 ! head
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0000153 ! anterior region of body
relationship: posteriorly_connected_to UBERON:0002100 ! trunk
property_value: curator_notes "true necks are considered to be present when the pectoral girdle is separate from the skull - Tiktaalik is the earliest known fish to have a true neck." xsd:string
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/9/99/Female_neck.jpg" xsd:anyURI
property_value: RO:0002174 NCBITaxon:32443 {source="ISBN:9780674021839"}
property_value: UBPROP:0000007 "cervical" xsd:string

[Term]
id: UBERON:0000977
name: pleura
namespace: uberon
def: "The invaginated serous membrane that surrounds the lungs (the visceral portion) and lines the walls of the pleural cavity (parietal portion)." [https://github.com/obophenotype/uberon/issues/1231, ISBN:0-683-40008-8, MP:0010820, UBERON:cjm, Wikipedia:Pulmonary_pleurae]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "pleura" RELATED []
synonym: "pleural tissue" RELATED [BTO:0001791, NCIT:C12469]
synonym: "wall of pleural sac" EXACT []
xref: BTO:0001791
xref: CALOHA:TS-2081
xref: EFO:0001980
xref: EMAPA:16775
xref: EV:0100044
xref: FMA:9583
xref: GAID:360
xref: MA:0000433
xref: MESH:D010994
xref: NCIT:C12469
xref: SCTID:181609007
xref: UMLS:C0032225 {source="ncithesaurus:Pleural_Tissue"}
xref: VHOG:0000394
xref: Wikipedia:Pleura
is_a: UBERON:0000042 ! serous membrane
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: has_part UBERON:0002400 ! parietal pleura
intersection_of: has_part UBERON:0002401 ! visceral pleura
intersection_of: part_of UBERON:0009778 ! pleural sac
relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system
relationship: develops_from UBERON:0003081 ! lateral plate mesoderm
relationship: has_part UBERON:0002400 ! parietal pleura
relationship: has_part UBERON:0002401 ! visceral pleura
relationship: has_quality PATO:0001748 ! invaginated
relationship: only_in_taxon NCBITaxon:32524 ! Amniota
relationship: part_of UBERON:0009778 {source="https://github.com/obophenotype/uberon/issues/86"} ! pleural sac
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:8782 {source="ISBN:978-0030223693", source="https://orcid.org/0000-0003-3308-6245"}
property_value: UBPROP:0000001 "The serous membrane that covers the lungs and lines the pleural cavity. [Kaufman_MH_and_Bard_JBL, The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.264][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000394", ontology="VHOG", source="ISBN:0124020607", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "pleural" xsd:string
property_value: UBPROP:0000012 "In MA, is_a cavity lining (which we equate to parietal). In FMA, is_a (viscous) serous membrane (which includes mesothelium plus connective tissue). Note the MA structure should probably be associated with the mesothelium of pleura in FMA. JB/EHDAA2 argues the term 'pleura' is best used for the mesothelial lining (thus excluding connective tissue). See https://github.com/obophenotype/uberon/issues/86" xsd:string

[Term]
id: UBERON:0000982
name: skeletal joint
namespace: uberon
def: "Anatomical structure that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000101, Wikipedia:Joint]
subset: efo_slim
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "articular joint" RELATED [BTO:0001686]
synonym: "articulation" BROAD [VSAO:0000101]
synonym: "joint" BROAD [FMA:7490, VSAO:0000101]
synonym: "joints" RELATED OMO:0003004 [ZFA:0001596]
xref: AEO:0000182
xref: BTO:0001686
xref: CALOHA:TS-2023
xref: EFO:0000948
xref: EMAPA:35456
xref: FMA:7490
xref: GAID:102
xref: galen:Joint
xref: MA:0000319
xref: MAT:0000188
xref: MESH:D007596
xref: MIAA:0000188
xref: NCIT:C13044
xref: RETIRED_EHDAA2:0003182
xref: SCTID:302536002
xref: TAO:0000367
xref: UMLS:C0022417 {source="ncithesaurus:Joint"}
xref: VHOG:0001276
xref: VSAO:0000101
xref: Wikipedia:Joint
xref: XAO:0000171
xref: ZFA:0001596
is_a: UBERON:0004905 ! articulation
union_of: UBERON:0002217 ! synovial joint
union_of: UBERON:0011134 ! nonsynovial joint
disjoint_from: UBERON:0001474 ! bone element
relationship: connects UBERON:0004765 ! skeletal element
relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system
property_value: UBPROP:0000001 "Anatomical cluster that consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000101", ontology="VSAO", source="PSPUB:0000170"}
property_value: UBPROP:0000001 "Anatomical cluster which consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000367", ontology="TAO", source="TAO:pem"}

[Term]
id: UBERON:0000988
name: pons
namespace: uberon
def: "The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum." [VHOG:0001176]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "pons cerebri" RELATED OMO:0003011 [NeuroNames:547]
synonym: "pons of Varolius" EXACT []
synonym: "pons Varolii" EXACT [ncithesaurus:Pons_Varolii]
xref: BAMS:PONS
xref: BAMS:Pons
xref: BIRNLEX:733
xref: BM:Pons
xref: BTO:0001101
xref: CALOHA:TS-0813
xref: DHBA:10661
xref: EFO:0001394
xref: EHDAA2:0004394
xref: EMAPA:17563
xref: EV:0100253
xref: FMA:67943
xref: GAID:578
xref: HBA:9131
xref: MA:0000204
xref: MAT:0000115
xref: MBA:771
xref: MESH:D011149
xref: MIAA:0000115
xref: NCIT:C12511
xref: neuronames:547 {source="BIRNLEX:733"}
xref: SCTID:279103004
xref: UMLS:C0032639 {source="BIRNLEX:733", source="ncithesaurus:Pons_Varolii"}
xref: UMLS:C1280999 {source="BIRNLEX:733"}
xref: VHOG:0001176
xref: Wikipedia:Pons
is_a: UBERON:0002616 ! regional part of brain
relationship: contributes_to_morphology_of UBERON:0001895 ! metencephalon
relationship: contributes_to_morphology_of UBERON:0002298 ! brainstem
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0001895 {source="neuronames"} ! metencephalon
relationship: part_of UBERON:0002298 ! brainstem
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/36/Gray768.png" xsd:anyURI
property_value: editor_note "The pons is not present in zebrafish. In this ontology we currently have some structures which are applicable to zebrafish appearing as parts of the pons. Currently we only include the weaker dubious_for_taxon relationship ubtil this is resolved" xsd:string
property_value: RO:0002174 NCBITaxon:7955
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001176", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/pons"}
property_value: UBPROP:0000003 "During the embryonic development of birds and mammals, neuroblasts migrate from the cerebellum into the ventral part of the rhombencephalon and differentiate into pontine and other nuclei, which relay information from between the cerebrum and cerebellum, and a conspicuous band of transverse fibers. This region is known as the pons. A pons does not differentiate in reptiles and anamniotes (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001176", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.474", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0000989
name: penis
namespace: uberon
def: "An intromittent organ in certain biologically male organisms. In placental mammals, this also serves as the organ of urination." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MP:0005187, Wikipedia:Penis]
subset: efo_slim
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "penes" RELATED OMO:0003004 []
synonym: "phallus" RELATED []
xref: BTO:0000405
xref: CALOHA:TS-0758
xref: EFO:0000987
xref: EHDAA2:0001433
xref: EHDAA:9380
xref: EMAPA:18682
xref: EMAPA_RETIRED:18996
xref: EV:0100107
xref: FMA:9707
xref: GAID:389
xref: galen:Penis
xref: MA:0000408
xref: MAT:0000186
xref: MESH:D010413
xref: MIAA:0000186
xref: NCIT:C12409
xref: SCTID:265793009
xref: UMLS:C0030851 {source="ncithesaurus:Penis"}
xref: VHOG:0000727
xref: Wikipedia:Penis
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0008811 {source="Wikipedia"} ! intromittent organ
relationship: develops_from UBERON:0004876 {source="Wikipedia"} ! urogenital fold
relationship: develops_from UBERON:0005876 {source="EHDAA2"} ! undifferentiated genital tubercle
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/87/Labelled_flaccid_penis.jpg" xsd:anyURI
property_value: UBPROP:0000007 "penile" xsd:string
property_value: UBPROP:0000007 "phallic" xsd:string
property_value: UBPROP:0000008 "Most male birds (e.g., roosters and turkeys) have a cloaca (also present on the female), but not a penis. Among bird species with a penis are paleognathes (tinamous and ratites), Anatidae (ducks, geese and swans), and a very few other species (such as flamingoes). A bird penis is different in structure from mammal penises, being an erectile expansion of the cloacal wall and being erected by lymph, not blood. It is usually partially feathered and in some species features spines and brush-like filaments, and in flaccid state curls up inside the cloaca" xsd:string {source="WP"}

[Term]
id: UBERON:0000990
name: reproductive system
namespace: uberon
def: "Anatomical system that has as its parts the organs concerned with reproduction." [Wikipedia:Reproductive_system]
subset: efo_slim
subset: functional_classification
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "animal reproductive system" RELATED [BTO:0000081]
synonym: "genital system" NARROW []
synonym: "genital tract" RELATED []
synonym: "genitalia" NARROW OMO:0003004 []
synonym: "Geschlechtsorgan" RELATED [BTO:0000081]
synonym: "organa genitalia" RELATED [BTO:0000081]
synonym: "reproductive tissue" RELATED [BTO:0000081]
synonym: "reproductive tract" RELATED []
synonym: "systemata genitalia" RELATED OMO:0003011 [Wikipedia:Reproductive_system]
xref: AAO:0010258
xref: BILA:0000103
xref: BTO:0000081
xref: CALOHA:TS-1318
xref: EFO:0000809
xref: EHDAA2:0001603
xref: EHDAA:5923
xref: EMAPA:17381
xref: EV:0100100
xref: FBbt:00004857 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:7160
xref: GAID:363
xref: HAO:0000374
xref: HAO:0000895
xref: MA:0000326
xref: MESH:D005835 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: MIAA:0000305
xref: NCIT:C12841
xref: SCTID:278875001
xref: TAO:0000632
xref: UMLS:C1261210 {source="ncithesaurus:Reproductive_System"}
xref: VHOG:0000182
xref: WBbt:0005747
xref: Wikipedia:Reproductive_system
xref: XAO:0000142
xref: ZFA:0000632
is_a: UBERON:0000467 ! anatomical system
intersection_of: UBERON:0000467 ! anatomical system
intersection_of: capable_of_part_of GO:0000003 ! reproduction
disjoint_from: UBERON:0001004 ! respiratory system
disjoint_from: UBERON:0001007 ! digestive system
disjoint_from: UBERON:0001009 ! circulatory system
disjoint_from: UBERON:0001016 ! nervous system
disjoint_from: UBERON:0001434 ! skeletal system
disjoint_from: UBERON:0002204 ! musculoskeletal system
disjoint_from: UBERON:0002294 ! biliary system
disjoint_from: UBERON:0002330 ! exocrine system
disjoint_from: UBERON:0002390 ! hematopoietic system
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: capable_of_part_of GO:0000003 ! reproduction
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: has_part UBERON:0000991 ! gonad
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/52/Penis.svg" xsd:anyURI
property_value: editor_note "consider splitting genitalia from reproductive system" xsd:string
property_value: http://purl.org/dc/terms/date "2022-06-10T18:22:34Z" xsd:dateTime
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anatomical system which consists of organs and tissues associated with sexual reproduction of the organism.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010258", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "Arguably, one of the most important aspects of urbilaterian organogenesis would have been gonadogenesis, since Urbilateria must have successfully generated gametes and developed a strategy for extrusion and fertilization, in order to be the ancestor of all living Bilateria.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000182", ontology="VHOG", source="PMID:21672850 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across Bilateria. Integrative and Comparative Biology (2007)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000202 FMA:75572

[Term]
id: UBERON:0000991
name: gonad
namespace: uberon
def: "Reproductive organ that produces and releases eggs (ovary) or sperm (testis)." [ISBN:0140512888, Wikipedia:Gonad, ZFA:0000413, ZFIN:curator]
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "gonada" EXACT []
synonym: "gonads" RELATED OMO:0003004 [ZFA:0000413]
xref: AAO:0000213
xref: BILA:0000123
xref: BSA:0000079
xref: BTO:0000534
xref: EMAPA:17383
xref: FBbt:00004858 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:18250
xref: GAID:368
xref: HAO:0000379
xref: MA:0002420
xref: MESH:D006066
xref: NCIT:C12725
xref: SCTID:304623008
xref: TAO:0000413
xref: UMLS:C0018067 {source="ncithesaurus:Gonad"}
xref: VHOG:0000397
xref: WBbt:0005175
xref: Wikipedia:Gonad
xref: XAO:0003146
xref: ZFA:0000413
is_a: UBERON:0003133 ! reproductive organ
intersection_of: UBERON:0003133 ! reproductive organ
intersection_of: has_part CL:0000586 ! germ cell
relationship: contains_process GO:0007276 ! gamete generation
relationship: develops_from UBERON:0005564 ! gonad primordium
relationship: has_part CL:0000586 ! germ cell
property_value: UBPROP:0000001 "Anatomical structure which produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000213", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The part of the reproductive system that produces and releases eggs (ovary) or sperm (testis).[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000413", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000397", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T, Capel B, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "gonadal" xsd:string
property_value: UBPROP:0000012 "FMA xref is a 'general anatomical term'" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0000992
name: ovary
namespace: uberon
def: "The gonad of a female organism which contains germ cells." [ISBN:0-683-40008-8, MP:0001126, Wikipedia:Ovary]
subset: efo_slim
subset: human_reference_atlas
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "animal ovary" EXACT [EFO:0000973]
synonym: "female gonad" EXACT []
synonym: "female organism genitalia gonad" EXACT [OBOL:automatic]
synonym: "female organism genitalia gonada" EXACT [OBOL:automatic]
synonym: "female organism reproductive system gonad" EXACT [OBOL:automatic]
synonym: "female organism reproductive system gonada" EXACT [OBOL:automatic]
synonym: "female reproductive system gonad" EXACT [OBOL:automatic]
synonym: "female reproductive system gonada" EXACT [OBOL:automatic]
synonym: "genitalia of female organism gonad" EXACT [OBOL:automatic]
synonym: "genitalia of female organism gonada" EXACT [OBOL:automatic]
synonym: "gonad of female organism genitalia" EXACT [OBOL:automatic]
synonym: "gonad of female organism reproductive system" EXACT [OBOL:automatic]
synonym: "gonad of female reproductive system" EXACT [OBOL:automatic]
synonym: "gonad of genitalia of female organism" EXACT [OBOL:automatic]
synonym: "gonad of reproductive system of female organism" EXACT [OBOL:automatic]
synonym: "gonada of female organism genitalia" EXACT [OBOL:automatic]
synonym: "gonada of female organism reproductive system" EXACT [OBOL:automatic]
synonym: "gonada of female reproductive system" EXACT [OBOL:automatic]
synonym: "gonada of genitalia of female organism" EXACT [OBOL:automatic]
synonym: "gonada of reproductive system of female organism" EXACT [OBOL:automatic]
synonym: "ovaries" RELATED OMO:0003004 []
synonym: "ovarium" RELATED OMO:0003011 [Wikipedia:Ovary]
synonym: "ovum-producing ovary" EXACT SENSU [GO:0061039]
synonym: "reproductive system of female organism gonad" EXACT [OBOL:automatic]
synonym: "reproductive system of female organism gonada" EXACT [OBOL:automatic]
xref: AAO:0000371
xref: BILA:0000125
xref: BSA:0000080
xref: BTO:0000975
xref: CALOHA:TS-0730
xref: EFO:0000973
xref: EHDAA2:0001360
xref: EHDAA:8124
xref: EMAPA:17962
xref: EV:0100111
xref: FBbt:00004865 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:7209
xref: GAID:367
xref: MA:0000384
xref: MESH:D010053
xref: MIAA:0000125
xref: NCIT:C12404
xref: SCTID:181464007
xref: TAO:0000403
xref: UMLS:C0029939 {source="ncithesaurus:Ovary"}
xref: VHOG:0000251
xref: Wikipedia:Ovary
xref: XAO:0000258
xref: ZFA:0000403
is_a: UBERON:0000991 ! gonad
is_a: UBERON:0003134 ! female reproductive organ
intersection_of: UBERON:0000991 ! gonad
intersection_of: part_of UBERON:0000474 ! female reproductive system
disjoint_from: UBERON:0009117 ! indifferent gonad
relationship: develops_from UBERON:0009117 ! indifferent gonad
relationship: in_lateral_side_of UBERON:0003975 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA-abduced-lr"} ! internal female genitalia
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray589.png" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Either of paired female reproductive organs involved in production of ova and female sex hormones.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000371", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "Female reproductive organ.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000403", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "(...) while it is likely that Urbilateria lacked a complex somatic reproductive system, it is at present impossible to speculate on whether or not it possessed a true gonad, let alone any other somatic adaptations for reproduction (reference 1); Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved (reference 2).[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000251", ontology="VHOG", source="DOI:10.1093/icb/icm052 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across the Bilateria. Integrative and Comparative Biology (2007), DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T and Capel B, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "ovarian" xsd:string
property_value: UBPROP:0000008 "Ovaries of some kind are found in the female reproductive system of many animals that employ sexual reproduction, including invertebrates. However, they develop in a very different way in most invertebrates than they do in vertebrates, and are not truly homologous. Many of the features found in human ovaries are common to all vertebrates, including the presence of follicular cells, tunica albuginea, and so on. However, many species produce a far greater number of eggs during their lifetime than do humans, so that, in fish and amphibians, there may be hundreds, or even millions of fertile eggs present in the ovary at any given time. In these species, fresh eggs may be developing from the germinal epithelium throughout life. Corpora lutea are found only in mammals, and in some elasmobranch fish; in other species, the remnants of the follicle are quickly resorbed by the ovary. In birds, reptiles, and monotremes, the egg is relatively large, filling the follicle, and distorting the shape of the ovary at maturity. Amphibians and reptiles have no ovarian medulla; the central part of the ovary is a hollow, lymph-filled space. The ovary of teleosts is also often hollow, but in this case, the eggs are shed into the cavity, which opens into the oviduct. Although most normal female vertebrates have two ovaries, this is not the case in all species. In birds and platypuses, the right ovary never matures, so that only the left is functional. In some elasmobranchs, the reverse is true, with only the right ovary fully developing. In the primitive jawless fish, and some teleosts, there is only one ovary, formed by the fusion of the paired organs in the embryo" xsd:string {source="WP"}

[Term]
id: UBERON:0000993
name: oviduct
namespace: uberon
def: "A tube or collection of tubes in an animal from the ovaries to the outside of the body." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "female reproductive tracts" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "ovarian duct" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "ovarian tube" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "oviducts" RELATED OMO:0003004 [ZFA:0000560]
synonym: "tuba uterina" RELATED [BTO:0000980]
synonym: "tuba uterinae" RELATED [BTO:0000980]
synonym: "tubular parts of female reproductive system" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "uterine tube" EXACT []
xref: AAO:0010533
xref: BSA:0000083
xref: BTO:0000980
xref: EFO:0000974
xref: EMAPA:18984
xref: GAID:366
xref: MAT:0000126
xref: MESH:D010057
xref: MIAA:0000126
xref: NCIT:C77957
xref: TAO:0000560
xref: UMLS:C0029954 {source="ncithesaurus:Oviduct"}
xref: VHOG:0001136
xref: Wikipedia:Oviduct
xref: XAO:0003052
xref: ZFA:0000560
is_a: UBERON:0000025 ! tube
is_a: UBERON:0005156 ! reproductive structure
relationship: connects UBERON:0000992 ! ovary
relationship: connects UBERON:0013514 ! space surrounding organism
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000474 ! female reproductive system
property_value: curator_notes "sometimes oviduct is used interchangeably with follaopian tube. Here they are different - the oviduct connects the gonad to the outside in a variety of animals. The mammal-class fallopian tube is derived from the mullerian duct and connects the gonads/infubdibulum to the uterus" xsd:string
property_value: UBPROP:0000001 "A passage through which ova leave the maternal body or pass to an organ communicating with the exterior of the body. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001136", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/oviduct"}
property_value: UBPROP:0000003 "In all remaining vertebrates (i.e., coelacanths, lungfishes, amphibians, reptiles, birds, and mammals), the oviduct arises in ontogeny as a longitudinal, groovelike invagination of the coelomic epithelium on the lateral surface of the mesonephros.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001136", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.687-688", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "in birds divided into infundibulum, magnum, isthmus, uterus, and vagina" xsd:string
property_value: UBPROP:0000008 "The only female vertebrates to lack oviducts are the jawless fishes. In these species, the single fused ovary releases eggs directly into the body cavity. The fish eventually extrudes the eggs through small genital pores towards the rear of the body[WP]" xsd:string

[Term]
id: UBERON:0000995
name: uterus
namespace: uberon
def: "The female muscular organ of gestation in which the developing embryo or fetus is nourished until birth." [MGI:csmith, MP:0001120]
subset: efo_slim
subset: human_reference_atlas
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
xref: BTO:0001424
xref: CALOHA:TS-1102
xref: EFO:0000975
xref: EMAPA:29915
xref: EV:0100113
xref: FMA:17558
xref: GAID:172
xref: galen:Uterus
xref: MA:0000389
xref: MAT:0000127
xref: MESH:D014599
xref: MIAA:0000127
xref: NCIT:C12405
xref: SCTID:181452004
xref: UMLS:C0042149 {source="ncithesaurus:Uterus"}
xref: VHOG:0001137
xref: Wikipedia:Uterus
is_a: UBERON:0013515 {source="cjm"} ! subdivision of oviduct
relationship: develops_from UBERON:0005795 ! embryonic uterus
relationship: immediate_transformation_of UBERON:0005795 ! embryonic uterus
relationship: only_in_taxon NCBITaxon:32525 ! Theria <mammals>
relationship: part_of UBERON:0004175 ! internal genitalia
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6a/Female_reproductive_system_lateral_nolabel.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Uterus.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The hollow muscular organ in female mammals in which the blastocyst normally becomes embedded and in which the developing embryo and fetus is nourished. Its cavity opens into the vagina below and into a uterine tube on either side. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001137", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/uterus"}
property_value: UBPROP:0000003 "An infundibulum, uterine tube, uterus, and vagina also differentiate along the oviducts of eutherian mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001137", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.678", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "uterine" xsd:string
property_value: UBPROP:0000008 "Most animals that lay eggs, such as birds and reptiles, have an oviduct instead of a uterus. In monotremes, mammals which lay eggs and include the platypus, either the term uterus or oviduct is used to describe the same organ, but the egg does not develop a placenta within the mother and thus does not receive further nourishment after formation and fertilization. Marsupials have two uteruses, each of which connect to a lateral vagina and which both use a third, middle 'vagina' which functions as the birth canal. Marsupial embryos form a choriovitelline 'placenta' (which can be thought of as something between a monotreme egg and a 'true' placenta), in which the egg's yolk sac supplies a large part of the embryo's nutrition but also attaches to the uterine wall and takes nutrients from the mother's bloodstream." xsd:string
property_value: UBPROP:0000011 "Two uteruses usually form initially in a female fetus, and in placental mammals they may partially or completely fuse into a single uterus depending on the species. In many species with two uteruses, only one is functional. Humans and other higher primates such as chimpanzees, along with horses, usually have a single completely fused uterus, although in some individuals the uteruses may not have completely fused [Wikipedia:Uterus]" xsd:string

[Term]
id: UBERON:0000997
name: mammalian vulva
namespace: uberon
def: "External genital organs of the female mammal[WP]." [Wikipedia:Vulva]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "female pudendum" EXACT DEPRECATED [BTO:0003101, doi:10.1002/ca.23705, FMA:20462]
synonym: "mammalian vulva" EXACT []
synonym: "puboperineal region" EXACT [FMA:20462]
synonym: "pudendum" RELATED DEPRECATED [BTO:0003101, doi:10.1002/ca.23705]
synonym: "pudendum femininum" EXACT DEPRECATED [doi:10.1002/ca.23705, FMA:20462, FMA:TA]
synonym: "pudendum femininum" RELATED DEPRECATED [doi:10.1002/ca.23705, Wikipedia:Vulva]
synonym: "pudendum muliebre" RELATED DEPRECATED [BTO:0003101, doi:10.1002/ca.23705]
synonym: "vulva" EXACT [MA:0000395]
xref: BTO:0003101
xref: CALOHA:TS-1168
xref: EFO:0000978
xref: EMAPA:36631
xref: EV:0100118
xref: FMA:20462
xref: GAID:383
xref: galen:Vulva
xref: MA:0000395
xref: MAT:0000169
xref: MESH:D014844
xref: MIAA:0000169
xref: NCIT:C12408
xref: SCTID:265796001
xref: UMLS:C0042993 {source="ncithesaurus:Vulva"}
xref: VHOG:0001458
xref: Wikipedia:Vulva
is_a: UBERON:0000062 ! organ
is_a: UBERON:0005156 ! reproductive structure
relationship: only_in_taxon NCBITaxon:40674 ! Mammalia
relationship: part_of UBERON:0005056 ! external female genitalia
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Female_unshaved_genitalia.jpg" xsd:anyURI
property_value: UBPROP:0000001 "The external genital organs of the female, including the labia majora, labia minora, clitoris, and vestibule of the vagina. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001458", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/vulva"}
property_value: UBPROP:0000007 "vulval" xsd:string

[Term]
id: UBERON:0000998
name: seminal vesicle
namespace: uberon
def: "Either of a pair of glandular pouches that lie one on either side of the male reproductive tract posterolateral to the urinary bladder and in the human male secrete a sugar- and protein-containing fluid into the ejaculatory duct." [BTO:0001234, Wikipedia:Seminal_vesicle]
subset: efo_slim
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "glandula seminalis" RELATED [BTO:0001234]
synonym: "glandula vesiculosa" RELATED [BTO:0001234]
synonym: "gonecyst" RELATED []
synonym: "seminal gland" BROAD []
synonym: "vas efferens" RELATED []
synonym: "vesicula seminalis" RELATED [BTO:0001234, Wikipedia:Seminal_vesicle]
synonym: "vesiculae seminales" RELATED OMO:0003011 [Wikipedia:Seminal_vesicle]
synonym: "vesicular gland" RELATED [Wikipedia:Seminal_vesicle]
synonym: "vesicular glands" RELATED [Wikipedia:Seminal_vesicle]
synonym: "vesicular seminalis" RELATED [Wikipedia:Seminal_vesicle]
synonym: "vesiculæ seminales" RELATED [Wikipedia:Seminal_vesicle]
xref: AAO:0010788
xref: BTO:0001234
xref: CALOHA:TS-0919
xref: EFO:0000986
xref: EMAPA:19180
xref: EV:0100106
xref: FMA:19386
xref: GAID:394
xref: MA:0000410
xref: MAT:0000171
xref: MESH:D012669
xref: MIAA:0000171
xref: NCIT:C12787
xref: SCTID:181434004
xref: UMLS:C0036628 {source="ncithesaurus:Seminal_Vesicle"}
xref: VHOG:0001379
xref: Wikipedia:Seminal_vesicle
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0006868 ! seminal fluid secreting gland
relationship: contributes_to_morphology_of UBERON:0004054 ! internal male genitalia
relationship: develops_from UBERON:0000080 ! mesonephros
relationship: part_of UBERON:0000473 ! testis
relationship: produces UBERON:0010143 ! seminal vesicle fluid
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI
property_value: UBPROP:0000001 "Either of a pair of pouchlike glands situated on each side of the male urinary bladder that secrete seminal fluid and nourish and promote the movement of spermatozoa through the urethra. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001379", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/prominence"}
property_value: UBPROP:0000003 "(In mammalian testis) Along the way (the sperm travel), three accessory sex glands, the seminal vesicle, prostate, and bulbourethral (Cowper's) gland, respectively, add their secretions as sperm move from the testes to the urethra.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001379", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.556", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000009 "The seminal vesicles secrete a significant proportion of the fluid that ultimately becomes semen. Lipofuscin granules from dead epithelial cells give the secretion its yellowish color. About 50-70% of the seminal fluid in humans originates from the seminal vesicles, but is not expelled in the first ejaculate fractions which are dominated by spermatozoa and zinc-rich prostatic fluid." xsd:string

[Term]
id: UBERON:0000999
name: ejaculatory duct
namespace: uberon
def: "The Ejaculatory ducts (ductus ejaculatorii) are paired structures in male anatomy, about 2 cm in length. Each ejaculatory duct is formed by the union of the vas deferens with the duct of the seminal vesicle. They pass through the prostate, and empty into the urethra at the Colliculus seminalis. During ejaculation, semen passes through the ducts and exits the body via the penis[WP,unvetted]." [Wikipedia:Ejaculatory_duct]
subset: efo_slim
subset: uberon_slim
synonym: "ductus ejaculatorii" EXACT OMO:0003004 [BTO:0001580]
synonym: "ductus ejaculatorii" RELATED OMO:0003011 [Wikipedia:Ejaculatory_duct]
synonym: "ductus ejaculatorius" EXACT [BTO:0001580]
xref: BTO:0001580
xref: CALOHA:TS-0211
xref: EFO:0000985
xref: EMAPA:19088
xref: FMA:19325
xref: GAID:388
xref: MA:0003247
xref: MAT:0000170
xref: MESH:D004543
xref: MIAA:0000170
xref: NCIT:C32493
xref: SCTID:279665005
xref: UMLS:C0013747 {source="ncithesaurus:Ejaculatory_Duct"}
xref: Wikipedia:Ejaculatory_duct
is_a: UBERON:0000025 ! tube
is_a: UBERON:0005904 ! duct of male reproductive system
is_a: UBERON:0015212 ! lateral structure
relationship: capable_of_part_of GO:0042713 ! sperm ejaculation
relationship: channel_for UBERON:0001968 ! semen
relationship: channel_for UBERON:0010143 ! seminal vesicle fluid
relationship: channels_from UBERON:0000998 ! seminal vesicle
relationship: channels_from UBERON:0001000 ! vas deferens
relationship: channels_into UBERON:0000057 ! urethra
relationship: in_lateral_side_of UBERON:0000079 ! male reproductive system
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png" xsd:anyURI

[Term]
id: UBERON:0001000
name: vas deferens
namespace: uberon
def: "A secretory duct that transports sperm from the testis. In mammals this is a continuation of the epididymis and ends in the prostatic urethra where it terminates to form ejaculatory duct." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MGI:pvb, MP:0002769, Wikipedia:Vas_deferens]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "deferent duct" EXACT []
synonym: "ductus deferens" EXACT [Wikipedia:Vas_deferens]
synonym: "sperm duct" RELATED []
synonym: "vas deferen" EXACT []
synonym: "vasa deferentia" RELATED []
xref: BTO:0001427
xref: CALOHA:TS-1105
xref: EFO:0000981
xref: EMAPA:18681
xref: EV:0100105
xref: FMA:19234
xref: GAID:404
xref: galen:VasDeferens
xref: MA:0000413
xref: MESH:D014649
xref: MIAA:0000129
xref: NCIT:C12813
xref: SCTID:245467009
xref: UMLS:C0042360 {source="ncithesaurus:Vas_Deferens"}
xref: VHOG:0001135
xref: Wikipedia:Vas_deferens
is_a: UBERON:0000025 ! tube
is_a: UBERON:0005904 ! duct of male reproductive system
relationship: channel_for UBERON:0001968 ! semen
relationship: channels_from UBERON:0001301 ! epididymis
relationship: channels_into UBERON:0000999 ! ejaculatory duct
relationship: contributes_to_morphology_of UBERON:0004054 ! internal male genitalia
relationship: only_in_taxon NCBITaxon:32524 ! Amniota
relationship: part_of UBERON:0005352 {source="FMA"} ! spermatic cord
relationship: part_of UBERON:0006947 ! male genital duct
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg" xsd:anyURI
property_value: UBPROP:0000003 "The continuation of the archinephric duct, now called the deferent duct, extends caudally to the cloaca or to the part of the mammalian urethra that is derived from the cloaca.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001135", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.670", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "Most vertebrates have some form of duct to transfer the sperm from the testes to the urethra. In cartilaginous fish and amphibians, sperm is carried through the archinephric duct, which also partially helps to transport urine from the kidneys. In teleosts, there is a distinct sperm duct, separate from the ureters, and often called the vas deferens, although probably not truly homologous with that in humans. In cartilaginous fishes, the part of the archinephric duct closest to the testis is coiled up to form an epididymis. Below this are a number of small glands secreting components of the seminal fluid. The final portion of the duct also receives ducts from the kidneys in most species. In amniotes, however, the archinephric duct has become a true vas deferens, and is used only for conducting sperm, never urine. As in cartilaginous fish, the upper part of the duct forms the epididymis. In many species, the vas deferens ends in a small sac for storing sperm. The only vertebrates to lack any structure resembling a vas deferens are the primitive jawless fishes, which release sperm directly into the body cavity, and then into the surrounding water through a simple opening in the body wall." xsd:string {source="WP"}

[Term]
id: UBERON:0001001
name: chitin-based cuticle
namespace: uberon
def: "A cuticular covering that is composed primarily of chitin. The main structural component of arthropod cuticle is a polysaccharide, chitin, composed of N-acetylglucosamine units, together with proteins and lipids[WP]." [https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/index.php?func=detail&aid=3348965&group_id=36855&atid=440764, Wikipedia:Arthropod_exoskeleton, Wikipedia:Cuticle#Invertebrate_zoology]
comment: EDITOR_NOTE TODO - split from exoskeleton? Also: See above sf item to see if this belongs in GO
subset: efo_slim
subset: uberon_slim
synonym: "arthropod cuticle" RELATED []
synonym: "arthropod exoskeleton" RELATED [Wikipedia:Arthropod_exoskeleton]
synonym: "cuticle" NARROW [FBbt:00004970]
synonym: "exoskeleton" BROAD []
synonym: "insect cuticle" RELATED []
xref: EFO:0000944
xref: FBbt:00004970 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: HAO:0000240
xref: MAT:0000150
xref: MIAA:0000150
xref: Wikipedia:Arthropod_exoskeleton
is_a: UBERON:0001002 ! cuticle
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0007491 ! chitin-based acellular structure
intersection_of: UBERON:0001002 ! cuticle
intersection_of: composed_primarily_of CHEBI:17029 ! chitin
relationship: develops_from UBERON:0007376 ! outer epithelium
relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda
relationship: part_of UBERON:0002416 ! integumental system

[Term]
id: UBERON:0001002
name: cuticle
namespace: uberon
def: "Tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Cuticles are non-homologous, differing in their origin, structure and chemical composition[WP]." [http://sourceforge.net/tracker/?func=detail&aid=3348965&group_id=36855&atid=440764, Wikipedia:Cuticle]
comment: EDITOR_NOTE TODO - check cuticle vs exoskeleton. Note that GO has a very generic definition of cuticle. See also arthropod-anatomy ontology. Note in ncit Cuticle is a plant part
subset: grouping_class
subset: non_informative
subset: uberon_slim
synonym: "cuticula" RELATED [BTO:0001600]
synonym: "cuticular exoskeleton" RELATED []
xref: BTO:0001600
xref: Wikipedia:Cuticle
is_a: UBERON:0000476 ! acellular anatomical structure
relationship: only_in_taxon NCBITaxon:6072 {source="Rieger - Evolution of the Cuticle in the Lower Eumetazoa"} ! Eumetazoa
property_value: UBPROP:0000007 "cuticular" xsd:string

[Term]
id: UBERON:0001003
name: skin epidermis
namespace: uberon
def: "The outer epithelial layer of the skin that is superficial to the dermis." [http://orcid.org/0000-0002-6601-2165, ISBN:0073040584]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "epidermis" BROAD []
synonym: "skin" BROAD []
synonym: "vertebrate epidermis" EXACT []
xref: AAO:0000143
xref: BTO:0000404
xref: CALOHA:TS-0283
xref: EFO:0000954
xref: EMAPA:17528
xref: EV:0100153
xref: FMA:70596
xref: GAID:932
xref: MA:0000153
xref: MAT:0000154
xref: MESH:D004817
xref: MIAA:0000154
xref: NCIT:C12708
xref: SCTID:361694003
xref: TAO:0000105
xref: UMLS:C0014520 {source="ncithesaurus:Epidermis"}
xref: VHOG:0000077
xref: Wikipedia:Epidermis_(skin)
xref: XAO:0000028
xref: ZFA:0000105
is_a: UBERON:0007376 ! outer epithelium
is_a: UBERON:3000961 ! external integument structure
intersection_of: UBERON:0007376 ! outer epithelium
intersection_of: part_of UBERON:0002097 ! skin of body
relationship: adjacent_to UBERON:0002067 ! dermis
relationship: developmentally_replaces UBERON:0003055 ! periderm
relationship: part_of UBERON:0002097 ! skin of body
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A cellular, multilayered epithelium derived from the ectoderm. Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000105", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000143", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000002 "relationship loss: subclass external integument structures (AAO:0000961)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000143", ontology="AAO"}
property_value: UBPROP:0000003 "(...) outer epithelia in all metazoan animals are homologous. (...) The ancestor of all metazoans likely had an epidermis with a basal extracellular matrix (ECM), an apical extracellular glycocalyx, and one cilium with a striated rootlet per cell.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000077", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.71-72", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "epidermal" xsd:string
property_value: UBPROP:0000008 "Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. In terrestrial vertebrates the epidermis often forms an outer keratinized or cornified layer, the stratum corneum. Interaction between the epideris and dermis gives rise to feathers (birds), hair and mammary glands (mammals), teeth and scales (placoid: chondrichthyans; cosmoids, ganoid, cycloid in bony fishes)." xsd:string

[Term]
id: UBERON:0001004
name: respiratory system
namespace: uberon
def: "Functional system which consists of structures involved in respiration." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Respiratory_system]
subset: efo_slim
subset: functional_classification
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "apparatus respiratorius" EXACT []
synonym: "apparatus respiratorius" RELATED [BTO:0000203]
synonym: "Atmungssystem" RELATED [BTO:0000203]
synonym: "respiratory system" EXACT []
synonym: "systema respiratorium" RELATED OMO:0003011 [Wikipedia:Respiratory_system]
xref: AAO:0000541
xref: BTO:0000203
xref: CALOHA:TS-1319
xref: EFO:0000804
xref: EHDAA2:0001604
xref: EHDAA:2203
xref: EMAPA:16727
xref: EV:0100036
xref: FMA:7158
xref: GAID:78
xref: MA:0000327
xref: MAT:0000030
xref: MESH:D012137
xref: MIAA:0000030
xref: NCIT:C12779
xref: SCTID:278197002
xref: TAO:0000272
xref: UMLS:C0035237 {source="ncithesaurus:Respiratory_System"}
xref: VHOG:0000202
xref: Wikipedia:Respiratory_system
xref: XAO:0000117
xref: ZFA:0000272
is_a: UBERON:0000467 ! anatomical system
intersection_of: UBERON:0000467 ! anatomical system
intersection_of: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system
disjoint_from: UBERON:0001007 ! digestive system
disjoint_from: UBERON:0001009 ! circulatory system
disjoint_from: UBERON:0001016 ! nervous system
disjoint_from: UBERON:0001434 ! skeletal system
disjoint_from: UBERON:0002204 ! musculoskeletal system
disjoint_from: UBERON:0002294 ! biliary system
disjoint_from: UBERON:0002330 ! exocrine system
disjoint_from: UBERON:0002390 ! hematopoietic system
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: capable_of GO:0003016 ! respiratory system process
relationship: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5e/Respiratory_system_complete_en.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Lung.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb" xsd:anyURI
property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The anatomical system in which the exchange of oxygen and carbon dioxide between the organism and its environment.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000541", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "There is no doubt that the primitive pattern of vertebrate air-breathing is the buccal pulse pump found in actinopterygian fishes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000202", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.599 and Figure 18-23", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001005
name: respiratory airway
namespace: uberon
def: "An airway through which respiratory air passes in organisms." [Wikipedia:Trachea]
subset: grouping_class
subset: uberon_slim
synonym: "airway" BROAD [http://orcid.org/0000-0002-6601-2165]
synonym: "airways" BROAD OMO:0003004 [http://orcid.org/0000-0002-6601-2165]
xref: FMA:265130
xref: SCTID:361380005
xref: Wikipedia:Trachea
is_a: UBERON:0003103 ! compound organ
is_a: UBERON:0004111 ! anatomical conduit
relationship: channel_for UBERON:0034874 ! air in respiratory system
relationship: part_of UBERON:0001004 ! respiratory system
property_value: curator_notes "This class generically groups trachea and analagous structures throughout metazoa. Consider renaming, as the term could be taken to mean lumen of tracheal system (e.g. in SNOMED). As a grouping class this is quite vague, as it is not clear where the airway begins and ends" xsd:string

[Term]
id: UBERON:0001007
name: digestive system
namespace: uberon
def: "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [FB:gg, NLM:alimentary+system, Wikipedia:Digestive_system]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "alimentary system" RELATED []
synonym: "alimentary tract" RELATED []
synonym: "gastrointestinal system" RELATED []
synonym: "gut" RELATED []
xref: AAO:0000129
xref: BILA:0000082
xref: BTO:0000058
xref: CALOHA:TS-1293
xref: EFO:0000793
xref: EV:0100056
xref: FBbt:00005055 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:7152
xref: GAID:278
xref: galen:DigestiveSystem
xref: MA:0002431
xref: MAT:0000018
xref: MESH:D004064
xref: MIAA:0000018
xref: ncithesaurus:Digestive_System
xref: SCTID:278859004
xref: TADS:0000170
xref: TAO:0000339
xref: WBbt:0005748
xref: Wikipedia:Digestive_system
xref: XAO:0000125
xref: ZFA:0000339
is_a: UBERON:0000467 ! anatomical system
intersection_of: UBERON:0000467 ! anatomical system
intersection_of: capable_of GO:0022600 ! digestive system process
disjoint_from: UBERON:0001009 ! circulatory system
disjoint_from: UBERON:0001016 ! nervous system
disjoint_from: UBERON:0001434 ! skeletal system
disjoint_from: UBERON:0002204 ! musculoskeletal system
disjoint_from: UBERON:0002294 ! biliary system
disjoint_from: UBERON:0002330 ! exocrine system
disjoint_from: UBERON:0002390 ! hematopoietic system
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: capable_of GO:0022600 ! digestive system process
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "An anatomical system consisting of the alimentary canal and digestive glands responsible for intake, absorption, digestion and excretion of food.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000129", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000007 "digestive" xsd:string
property_value: UBPROP:0000012 "many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001008
name: renal system
namespace: uberon
def: "The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products." [DOI:10.1371/journal.pone.0099864, GO:0072001]
comment: EDITOR_NOTE In various sources such as Encyclopedia Britannica, the excretory and urinary systems are indeed the same system (see wikipedia talk page); we merge two BTO classes here
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "excretory system" BROAD []
synonym: "renal or urinary system" RELATED [EHDAA:5901]
synonym: "renal/urinary system" RELATED []
synonym: "systema urinaria" EXACT [FMA:7159]
synonym: "systema urinarium" EXACT [BTO:0003092]
synonym: "urinary system" EXACT []
synonym: "urinary tract" EXACT []
xref: AAO:0010257
xref: BILA:0000015
xref: BTO:0001244
xref: BTO:0003092
xref: CALOHA:TS-1323
xref: EFO:0000803
xref: EHDAA2:0001601
xref: EHDAA:5901
xref: EMAPA:17366
xref: EV:0100095
xref: FBbt:00005056 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:7159
xref: GAID:391
xref: galen:UrinaryTract
xref: MA:0000325
xref: MAT:0000027
xref: MESH:D014551
xref: MIAA:0000027
xref: NCIT:C12413
xref: SCTID:362204003
xref: TADS:0000162
xref: TAO:0000163
xref: UMLS:C1508753 {source="ncithesaurus:Urinary_System"}
xref: VHOG:0000723
xref: WBbt:0005736
xref: Wikipedia:Excretory_system
xref: XAO:0000143
xref: ZFA:0000163
is_a: UBERON:8450002 ! excretory system
intersection_of: UBERON:8450002 ! excretory system
intersection_of: capable_of GO:0097254 ! renal tubular secretion
relationship: capable_of GO:0097254 ! renal tubular secretion
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: RO:0002161 NCBITaxon:110815 {source="Wikipedia"}
property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "An anatomical system which consists of organs and tissues which produce, store, and excrete urine.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010257", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "Evolution of vertebrate renal anatomy appears quite conservative when compared, for example, to evolution of respiratory and cardiovascular systems in vertebrates. Major anatomical changes in vertebrates kidneys separate those of birds and mammals from kidneys of lower vertebrates. General increase in animal size from fish to mammals is reflected by an increase in total number of nephrons per kidney, rather than by constant change in tubular dimensions.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000723", ontology="VHOG", source="ISBN:978-3540428541 Kapoor BG, Bhavna Khanna, Ichthyology Handbook (2004) p.406", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels" xsd:string {source="GO"}
property_value: UBPROP:0000008 "This definition is inclusive of the organs of the vertebrate renal system, as well as the Malpighian tubules of insects, and allows for future incorporation of structures such as the antennal glands of crustaceans" xsd:string {source="DOI:10.1371/journal.pone.0099864"}

[Term]
id: UBERON:0001009
name: circulatory system
namespace: uberon
def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system]
subset: human_reference_atlas
subset: uberon_slim
synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system]
xref: AAO:0000959
xref: CALOHA:TS-2103
xref: MESH:D002319 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: VHOG:0001248
xref: Wikipedia:Circulatory_system
is_a: UBERON:0000467 ! anatomical system
disjoint_from: UBERON:0001016 ! nervous system
disjoint_from: UBERON:0001434 ! skeletal system
disjoint_from: UBERON:0002204 ! musculoskeletal system
disjoint_from: UBERON:0002294 ! biliary system
disjoint_from: UBERON:0002330 ! exocrine system
disjoint_from: UBERON:0002390 ! hematopoietic system
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: capable_of GO:0003013 ! circulatory system process
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
property_value: curator_notes "the cardiovascular system and the lymphatic system are parts of the circulatory system" xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI
property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"}
property_value: RO:0002161 NCBITaxon:6073
property_value: RO:0002161 NCBITaxon:6157
property_value: RO:0002174 NCBITaxon:6231 {notes="WBbt coelomocyte currently classified as circulating cell"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anatomical system of ion binding, a pumping mechanism, and an efficient vascular system; consisting of the blood, heart, and blood and lymph vessels, respectively.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000959", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001248", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001013
name: adipose tissue
namespace: uberon
def: "Portion of connective tissue composed of adipocytes enmeshed in areolar tissue." [http://orcid.org/0000-0002-6601-2165, MESH:A10.165.114, MGI:cwg, MP:0000003, Wikipedia:Adipose_tissue]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "adipose" RELATED [BTO:0001487]
synonym: "bodyfat" RELATED [BTO:0001487]
synonym: "fat" EXACT [MA:0000009]
synonym: "fat tissue" EXACT []
synonym: "fatty depot" RELATED []
synonym: "fatty tissue" EXACT []
xref: AAO:0000001
xref: AEO:000020
xref: BTO:0001487
xref: CALOHA:TS-0013
xref: EFO:0000790
xref: EHDAA2:0003120
xref: EMAPA:35112
xref: EV:0100381
xref: FMA:20110
xref: GAID:920
xref: galen:FattyTissue
xref: MA:0000009
xref: MAT:0000015
xref: MESH:D000273
xref: MIAA:0000015
xref: NCIT:C12472
xref: SCTID:55603005
xref: TAO:0002134
xref: UMLS:C0001527 {source="ncithesaurus:Adipose_Tissue"}
xref: VHOG:0001284
xref: Wikipedia:Adipose_tissue
xref: XAO:0003049
xref: ZFA:0005345
is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: composed_primarily_of CL:0000136 ! adipocyte
disjoint_from: UBERON:0003714 ! neural tissue
relationship: composed_primarily_of CL:0000136 ! adipocyte
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Connective tissue in which fat is stored.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002134", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Tissue that contains adipocytes, used for cushioning, thermal insulation, lubrication (primarily in the pericardium) and energy storage.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000001", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000002 "relationship loss: subclass connective tissue proper (AAO:0000099)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000001", ontology="AAO"}
property_value: UBPROP:0000003 "Adipose tissue is unique to vertebrates. It is found in mostmammals, birds, reptiles and amphibians, and a variety is found in some species of fish. Furthermore, in insects the fat body found in larvae as well as in adults shares some homology with adipose tissue.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001284", ontology="VHOG", source="DOI:10.1017/S0029665107005423 Haugen F, Drevon CA, The interplay between nutrients and the adipose tissue. The Proceedings of the Nutrition Society (2007)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "adipose" xsd:string
property_value: UBPROP:0000008 "In humans, adipose tissue is located beneath the skin (subcutaneous fat), around internal organs (visceral fat), in bone marrow (yellow bone marrow) and in breast tissue. Adipose tissue is found in specific locations, which are referred to as adipose depots. Adipose tissue contains several cell types, with the highest percentage of cells being adipocytes, which contain fat droplets. Other cell types include fibroblasts, macrophages, and endothelial cells. Adipose tissue contains many small blood vessels.; Mice have eight major adipose depots, four of which are within the abdominal cavity. The paired gonadal depots are attached to the uterus and ovaries in females and the epididymis and testes in males; the paired retroperitoneal depots are found along the dorsal wall of the abdomen, surrounding the kidney, and, when massive, extend into the pelvis. The mesenteric depot forms a glue-like web that supports the intestines, and the omental depot, which originates near the stomach and spleen, and, when massive, extends into the ventral abdomen." xsd:string
property_value: UBPROP:0000012 "in FMA this is dense irregular connective tissue" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001015
name: musculature
namespace: uberon
def: "A subdivision of the muscular system corresponding to a subdisivision of an organism." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Muscular_system]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "muscle group" EXACT []
synonym: "muscle system" RELATED []
synonym: "muscles" RELATED []
synonym: "muscles set" EXACT []
synonym: "musculature" EXACT []
synonym: "musculature system" RELATED []
synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA]
synonym: "set of muscles" EXACT [FMA:32558]
synonym: "set of skeletal muscles" EXACT [MA:0000165]
xref: AAO:0011066
xref: BTO:0000887
xref: EFO:0001949
xref: EMAPA:32715
xref: EMAPA:35577
xref: FMA:32558
xref: MA:0000165
xref: NCIT:C13056
xref: TAO:0000548
xref: UMLS:C0026845 {source="ncithesaurus:Muscle"}
xref: VSAO:0005038
xref: WBbt:0005737
xref: Wikipedia:Muscular_system
xref: ZFA:0000548
is_a: UBERON:0011216 ! organ system subdivision
relationship: composed_primarily_of UBERON:0001630 ! muscle organ
relationship: part_of UBERON:0000383 ! musculature of body
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e5/Muscles_anterior_labeled.png" xsd:anyURI
property_value: RO:0002171 UBERON:0001474
property_value: UBPROP:0000012 "In FMA this is classified as a set of organs. ZFA musculature system has subtypes, so it is classified here. WBbt muscular system has subtypes so it goes here. Note that we use the MA term set of skeletal muscles here as it seems most appropriate (*not* MA:musculature). AAO is generally confused here." xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001016
name: nervous system
namespace: uberon
def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator]
subset: cumbo
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "nerve net" NARROW [Wikipedia:Nerve_net]
synonym: "neurological system" EXACT [GO:0050877]
synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system]
xref: AAO:0000324
xref: BILA:0000079
xref: BIRNLEX:844
xref: BTO:0001484
xref: CALOHA:TS-1313
xref: EFO:0000802
xref: EHDAA2:0001246
xref: EHDAA:826
xref: EMAPA:16469
xref: EV:0100162
xref: FBbt:00005093 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:7157
xref: GAID:466
xref: MA:0000016
xref: MAT:0000026
xref: MESH:D009420
xref: MIAA:0000026
xref: NCIT:C12755
xref: neuronames:3236
xref: SCTID:278196006
xref: TAO:0000396
xref: UMLS:C0027763 {source="ncithesaurus:Nervous_System"}
xref: VHOG:0000402
xref: WBbt:0005735
xref: Wikipedia:Nervous_system
xref: XAO:0000177
xref: ZFA:0000396
is_a: UBERON:0000467 ! anatomical system
disjoint_from: UBERON:0001434 ! skeletal system
disjoint_from: UBERON:0002204 ! musculoskeletal system
disjoint_from: UBERON:0002294 ! biliary system
disjoint_from: UBERON:0002330 ! exocrine system
disjoint_from: UBERON:0002390 ! hematopoietic system
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: capable_of GO:0050877 ! nervous system process
relationship: composed_primarily_of CL:0002319 ! neural cell
relationship: develops_from UBERON:0016880 ! future nervous system
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: has_part CL:0000540 ! neuron
relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI
property_value: RO:0002161 NCBITaxon:6040
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000324", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000402", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "nervous" xsd:string
property_value: UBPROP:0000007 "neural" xsd:string

[Term]
id: UBERON:0001017
name: central nervous system
namespace: uberon
def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/]
subset: cumbo
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cerebrospinal axis" NARROW [FMA:55675]
synonym: "CNS" EXACT OMO:0003000 []
synonym: "neuraxis" RELATED [FMA:55675]
synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA]
xref: AAO:0000090
xref: BAMS:CNS
xref: BILA:0000080
xref: BIRNLEX:1099
xref: BTO:0000227
xref: CALOHA:TS-0150
xref: EFO:0000908
xref: EHDAA2:0000225
xref: EHDAA:828
xref: EMAPA:16470
xref: EMAPA:16754
xref: EV:0100163
xref: FBbt:00005094 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:55675
xref: GAID:570
xref: MA:0000167
xref: MAT:0000457
xref: MESH:D002490
xref: NCIT:C12438
xref: neuronames:854
xref: SCTID:278199004
xref: TAO:0000012
xref: UMLS:C0927232 {source="ncithesaurus:Central_Nervous_System", source="BIRNLEX:1099"}
xref: VHOG:0000293
xref: Wikipedia:Central_nervous_system
xref: XAO:0000215
xref: ZFA:0000012
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0011216 {source="FBbt", source="cjm"} ! organ system subdivision
relationship: develops_from UBERON:0001049 {gci_relation="part_of", gci_filler="NCBITaxon:7742", evidence="definitional"} ! neural tube
relationship: develops_from UBERON:0016879 ! future central nervous system
relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! future central nervous system
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
relationship: part_of UBERON:0001016 ! nervous system
property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"}
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000293", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001021
name: nerve
namespace: uberon
def: "An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures." [FBbt:00005105, http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "nerves" EXACT OMO:0003004 [TAO:0007009]
synonym: "neural subtree" RELATED [FMA:65132]
synonym: "peripheral nerve" EXACT [http://orcid.org/0000-0002-6601-2165]
xref: AAO:0011070
xref: AEO:0000137
xref: BAMS:n
xref: BIRNLEX:1615
xref: BSA:0000098
xref: BTO:0000925
xref: BTO:0001027
xref: CALOHA:TS-0772
xref: EHDAA2:0003137
xref: EHDAA:2851
xref: EHDAA:3776
xref: EHDAA:4657
xref: EMAPA:32808
xref: EMAPA:32815
xref: EV:0100371
xref: FBbt:00005105 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:65132
xref: FMA:65239
xref: GAID:747
xref: GAID:758
xref: galen:Nerve
xref: MA:0000217
xref: MA:0000228
xref: MESH:D010525
xref: NCIT:C12466
xref: NCIT:C12768
xref: NLX:147826
xref: SCTID:244457007
xref: SCTID:256864008
xref: TAO:0007009
xref: UMLS:C0027740 {source="ncithesaurus:Nerve"}
xref: UMLS:C0031119 {source="ncithesaurus:Peripheral_Nerve"}
xref: VHOG:0000901
xref: Wikipedia:Nervous_system
xref: XAO:0000204
xref: XAO:0003047
xref: ZFA:0007009
is_a: UBERON:0000122 {source="FBbt"} ! neuron projection bundle
relationship: has_developmental_contribution_from UBERON:0002342 {gci_relation="part_of", gci_filler="NCBITaxon:7742", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! neural crest
relationship: has_quality PATO:0002045 ! dendritic
relationship: part_of UBERON:0000010 ! peripheral nervous system
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A portion of tissue which is a fasiculated group of axons.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0007009", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000007 "nervous" xsd:string

[Term]
id: UBERON:0001027
name: sensory nerve
namespace: uberon
def: "A nerve that transmits from sensory receptors on the surface of the body to the central nervous system." [UBERON:cjm, Wikipedia:Sensory_nerve]
subset: pheno_slim
subset: uberon_slim
synonym: "afferent nerve" RELATED []
synonym: "nervus sensorius" EXACT OMO:0003011 [Wikipedia:Sensory_nerve]
xref: AEO:0000201
xref: EHDAA2:0003200
xref: FBbt:00005136 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:5868
xref: Wikipedia:Sensory_nerve
is_a: UBERON:0001021 ! nerve
relationship: has_part CL:0000526 {source="AEO"} ! afferent neuron

[Term]
id: UBERON:0001032
name: sensory system
namespace: uberon
def: "Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information." [Wikipedia:Sensory_system]
subset: efo_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "organa sensuum" EXACT OMO:0003011 [FMA:75259, FMA:TA]
synonym: "organa sensuum" RELATED OMO:0003011 [Wikipedia:Sensory_system]
synonym: "sense organ subsystem" EXACT []
synonym: "sense organs" EXACT [FMA:75259]
synonym: "sense organs set" EXACT [FMA:75259]
synonym: "sensory organ system" RELATED []
synonym: "sensory subsystem" EXACT []
synonym: "sensory systems" EXACT OMO:0003004 [TAO:0000282]
synonym: "set of sense organs" RELATED [FMA:75259]
xref: AAO:0000555
xref: BAMS:SEN
xref: BILA:0000099
xref: EFO:0000805
xref: EHDAA2:0003094
xref: EMAPA:16192
xref: FBbt:00007692 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:75259
xref: MA:0002442
xref: MAT:0000031
xref: MIAA:0000031
xref: NLXANAT:090816
xref: TAO:0000282
xref: VHOG:0001674
xref: Wikipedia:Sensory_system
xref: XAO:0003194
xref: ZFA:0000282
is_a: UBERON:0015203 ! non-connected functional system
relationship: capable_of_part_of GO:0007600 ! sensory perception
relationship: overlaps UBERON:0001016 ! nervous system
relationship: part_of UBERON:0004456 ! entire sense organ system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray722.png" xsd:anyURI
property_value: UBPROP:0000003 "An early step in the evolution of neural crest, therefore, may have been the origin of a specific dorsal neural cell population contributing to sensory processing; this would predate the divergence of the amphioxus and vertebrate lineages.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001674", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "note the distinct between entire sensory system and individual system. this reconciles is_a and part_of distinctions between ssAOs" xsd:string

[Term]
id: UBERON:0001040
name: yolk sac
namespace: uberon
def: "A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]." [Wikipedia:Yolk_sac]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "saccus vitellinus" RELATED OMO:0003011 [Wikipedia:Yolk_sac]
synonym: "vesicula umbilicalis" RELATED OMO:0003011 [Wikipedia:Yolk_sac]
xref: BTO:0001471
xref: CALOHA:TS-1130
xref: EFO:0003078
xref: EHDAA2:0002212
xref: EHDAA:164
xref: EMAPA:16085
xref: FMA:87180
xref: GAID:1301
xref: MESH:D015017
xref: NCIT:C14128
xref: SCTID:362845002
xref: UMLS:C0043425 {source="ncithesaurus:Yolk_Sac"}
xref: VHOG:0000830
xref: Wikipedia:Yolk_sac
is_a: UBERON:0005292 ! extraembryonic tissue
is_a: UBERON:0005631 {seeAlso="https://github.com/obophenotype/uberon/issues/635"} ! extraembryonic membrane
is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac
relationship: has_developmental_contribution_from UBERON:0000925 {source="ISBN:0073040584"} ! endoderm
relationship: has_developmental_contribution_from UBERON:0004872 {source="ISBN:0073040584"} ! splanchnic layer of lateral plate mesoderm
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/17/Gray22.png" xsd:anyURI
property_value: editor_note "consider splitting class" xsd:string
property_value: UBPROP:0000001 "One of the extraembryonic fetal membranes that balloons out from the fetal midgut. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000830", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/yolk+sac"}
property_value: UBPROP:0000001 "the extraembryonic tissue membrane, formed from the visceral endoderm and the extraembryonic mesoderm, which is located ventral to the embryonic disc and is connected to the presumptive midgut of the embryo; the yolk that it contains is the site of embryonic hematopoiesis and vitelline circulation is involved in early embryonic circulation; it is the origin of the primordial germ cells" xsd:string {source="MP:0001718"}
property_value: UBPROP:0000003 "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000830", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.187", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "In therians, a structure homologous to the yolk sac is is present, but contains no yolk platelets. Instead it is filled with fluid [ISBN:0073040584 (Vertebrates, Kardong)]" xsd:string

[Term]
id: UBERON:0001041
name: foregut
namespace: uberon
def: "Anterior subdivision of a digestive tract." [http://orcid.org/0000-0002-6601-2165]
subset: developmental_classification
subset: pheno_slim
subset: uberon_slim
synonym: "praeenteron" RELATED OMO:0003011 [Wikipedia:Foregut]
synonym: "proenteron" RELATED OMO:0003011 [Wikipedia:Foregut]
xref: AAO:0011042
xref: BILA:0000085
xref: BTO:0000507
xref: EHDAA2:0000557
xref: EHDAA:520
xref: EMAPA:16548
xref: FBbt:00005379 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:45616
xref: MA:0001526
xref: NCIT:C34180
xref: SCTID:361409009
xref: TGMA:0001014
xref: UMLS:C0231051 {source="ncithesaurus:Foregut"}
xref: VHOG:0000285
xref: Wikipedia:Foregut
xref: XAO:0000232
is_a: UBERON:0004921 ! subdivision of digestive tract
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/9a/Gray27.png" xsd:anyURI
property_value: editor_note "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. In vertebrates the term may refer to a developmental structure" xsd:string
property_value: UBPROP:0000001 "The anterior portion of the primitive digestive tube of the embryo that lies cephalic to the junction of the yolk stalk, consists of endodermal tissue, and gives rise to the the pharynx, lower respiratory system, esophagus, stomach, duodenum proximal to the biliary tract, liver, pancreas, biliary tract, and gall bladder." xsd:string {source="MP:0000474"}
property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000285", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001042
name: chordate pharynx
namespace: uberon
def: "A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]." [http://www.feedexp.org]
comment: Consider generalizing to deuterostome pharynx
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "pharynx" BROAD SENSU [FMA:46688]
xref: AAO:0000967
xref: BTO:0001049
xref: CALOHA:TS-0785
xref: EFO:0000836
xref: EHDAA2:0001458
xref: EHDAA:2947
xref: EMAPA:16706
xref: EV:0100065
xref: FMA:46688
xref: GAID:155
xref: galen:Pharynx
xref: MA:0000432
xref: MESH:D010614
xref: NCIT:C12425
xref: SCTID:181211006
xref: TAO:0000056
xref: UMLS:C0031354 {source="ncithesaurus:Pharynx"}
xref: VHOG:0000462
xref: Wikipedia:Pharynx
xref: XAO:0003227
xref: ZFA:0000056
is_a: UBERON:0006562 ! pharynx
relationship: continuous_with UBERON:0001043 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! esophagus
relationship: develops_from UBERON:0009145 {source="EHDAA2"} ! pharyngeal region of foregut
relationship: distally_connected_to UBERON:0001043 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! esophagus
relationship: has_skeleton UBERON:0008895 {gci_relation="part_of", gci_filler="NCBITaxon:89593"} ! splanchnocranium
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
relationship: part_of UBERON:0001004 ! respiratory system
property_value: UBPROP:0000001 "A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNYX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx)[MESH:A03.867]." xsd:string {source="MESH:A03.867"}
property_value: UBPROP:0000001 "Anatomical cavity bounded by the derivatives of the branchial arches.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000967", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "Swollen region of the anterior foregut, posterior to the mouth and anterior to the liver; its walls form the jaws and gills. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000056", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Swollen region of the anterior foregut, posterior to the mouth and anterior to the liver; its walls form the jaws and gills[ZFA:0000056, ZFIN:ZDB-PUB-961014-576]." xsd:string {source="ZFIN:ZDB-PUB-961014-576"}
property_value: UBPROP:0000001 "The portion of the alimentary canal between the mouth and the oesophagus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000462", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000002 "relationship type change: part_of_proxy respiratory system (AAO:0000541) CHANGED TO: develops_from respiratory system (UBERON:0001004)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000967", ontology="AAO"}
property_value: UBPROP:0000002 "relationship type change: part_of_proxy respiratory system (AAO:0000541) CHANGED TO: part_of respiratory system (UBERON:0001004)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000967", ontology="AAO"}
property_value: UBPROP:0000003 "(...) the earliest vertebrates possessed unjointed internal and external branchial arches, and musculature encircling the pharynx.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000462", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) Box essay 13.1 and Box figure I, p.502-503", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "MA/FMA pharynx not part of digestive/alimentary system, we are consistent with this scheme" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001043
name: esophagus
namespace: uberon
def: "Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993)." [http://www.rivm.nl/interspeciesinfo/inter/oesophagus/, Wikipedia:Esophagus]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "gullet" EXACT []
synonym: "oesophagus" EXACT []
xref: AAO:0000145
xref: ANISEED:1235301
xref: BTO:0000959
xref: CALOHA:TS-0700
xref: EFO:0000835
xref: EHDAA2:0001285
xref: EHDAA:2937
xref: EMAPA:16833
xref: EV:0100069
xref: FMA:7131
xref: GAID:291
xref: galen:Esophagus
xref: MA:0000352
xref: MAT:0000048
xref: MESH:D004947
xref: MIAA:0000048
xref: NCIT:C12389
xref: SCTID:181245004
xref: TAO:0000204
xref: UMLS:C0014876 {source="ncithesaurus:Esophagus"}
xref: VHOG:0000450
xref: Wikipedia:Esophagus
xref: XAO:0000127
xref: ZFA:0000204
is_a: UBERON:0004921 ! subdivision of digestive tract
is_a: UBERON:0005178 ! thoracic cavity element
is_a: UBERON:0013765 ! digestive system element
relationship: develops_from UBERON:0001041 ! foregut
relationship: distally_connected_to UBERON:0000945 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="only in species that have a stomach"} ! stomach
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0004908 ! upper digestive tract
relationship: proximally_connected_to UBERON:0001042 ! chordate pharynx
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anterior end of the alimentary canal lined with smooth muscle. Bounded anteriorly by a constriction in the pharynx. Bounded posteriorly by and increase in circular and/or longitudinal smooth muscle associated with the stomach.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000145", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "The few structural specializations in (adult lampreys) pharynx include complex valves on the external gill openings that direct the tidal flow, and the division of the ancestral pharynx into an oesophagus and a respiratory pharynx.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000450", ontology="VHOG", source="DOI:10.1111/j.1096-3642.1996.tb01658.x Mallatt J, Ventilation and the origin of jawed vertebrates: a new mouth. Zoological Journal of the Linnean Society (1996)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "esophageal" xsd:string
property_value: UBPROP:0000012 "esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995)" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001045
name: midgut
namespace: uberon
def: "Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]." [GO:0007494, Wikipedia:Midgut]
subset: developmental_classification
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "mesenteron" RELATED OMO:0003011 [Wikipedia:Midgut]
xref: BILA:0000086
xref: BTO:0000863
xref: EFO:0001950
xref: EHDAA2:0001185
xref: EHDAA:983
xref: EMAPA:16255
xref: FBbt:00005383 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:45617
xref: MA:0001564
xref: NCIT:C34210
xref: SCTID:361410004
xref: TGMA:0001036
xref: UMLS:C0231052 {source="ncithesaurus:Midgut"}
xref: VHOG:0000290
xref: Wikipedia:Midgut
xref: XAO:0000103
is_a: UBERON:0004921 ! subdivision of digestive tract
relationship: part_of RO:0002577 ! system
relationship: proximally_connected_to UBERON:0001041 ! foregut
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/3d/Illu_small_intestine.jpg" xsd:anyURI
property_value: editor_note "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. We may explicitly make this a developmental class" xsd:string
property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000290", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "In humans: originates from the foregut at the opening of the bile duct into the duodenum and continues through the small intestine and much of the large intestine until the transition to the hindgut about two-thirds of the way through the transverse colon" xsd:string {source="WP"}
property_value: UBPROP:0000012 "in FMA this represents an embryonic region." xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001046
name: hindgut
namespace: uberon
def: "The caudalmost subdivision of a digestive tract." [http://orcid.org/0000-0002-6601-2165]
subset: developmental_classification
subset: pheno_slim
subset: uberon_slim
synonym: "metenteron" RELATED OMO:0003011 [Wikipedia:Hindgut]
xref: AAO:0011052
xref: BILA:0000087
xref: BTO:0000510
xref: EHDAA2:0000779
xref: EHDAA:975
xref: EMAPA:16715
xref: FBbt:00005384 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:45618
xref: MA:0001527
xref: NCIT:C34188
xref: SCTID:362856002
xref: TGMA:0001020
xref: UMLS:C0231053 {source="ncithesaurus:Hindgut"}
xref: VHOG:0000459
xref: Wikipedia:Hindgut
xref: XAO:0000104
is_a: UBERON:0004921 ! subdivision of digestive tract
relationship: develops_from UBERON:0003104 {source="Wikipedia"} ! mesenchyme
relationship: part_of RO:0002577 ! system
relationship: proximally_connected_to UBERON:0001045 ! midgut
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png" xsd:anyURI
property_value: editor_note "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future (vertebrates have some contribution from NC - https://github.com/obophenotype/uberon/wiki/The-neural-crest). We may explicitly make this a developmental class" xsd:string
property_value: UBPROP:0000001 "the caudal portion of the primitive digestive tube of the embryo" xsd:string {source="MP:0008786"}
property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000459", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "in FMA this class has no children. In MA it has a single child hindgut epithelium" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001048
name: primordium
namespace: uberon
def: "Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]." [BTO:0001886, FB:DJS, FB:FBrf0089570, http://flybase.org/reports/FBrf0178740.html]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "bud" RELATED []
synonym: "future organ" RELATED []
synonym: "placode" RELATED [FBbt:00005495]
synonym: "primordia" RELATED OMO:0003004 [XAO:0003043]
synonym: "rudiment" RELATED []
xref: AEO:0000171
xref: BTO:0001886
xref: EFO:0001652
xref: EHDAA2:0003171
xref: FBbt:00005495 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:86589
xref: MAT:0000482
xref: NCIT:C34275
xref: UMLS:C0678727 {source="ncithesaurus:Primordium"}
xref: Wikipedia:Primordium
xref: XAO:0003043
is_a: UBERON:0005423 {source="EHDAA2"} ! developing anatomical structure
relationship: part_of UBERON:0000468 ! multicellular organism

[Term]
id: UBERON:0001049
name: neural tube
namespace: uberon
def: "In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]." [Wikipedia:Neural_tube]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "neural primordium" RELATED []
synonym: "presumptive central nervous system" RELATED []
synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube]
xref: AAO:0010617
xref: BTO:0001057
xref: CALOHA:TS-2371
xref: DHBA:10154
xref: EHDAA2:0001254
xref: EHDAA:2869
xref: EHDAA:908
xref: EMAPA:16164
xref: EMAPA:16757
xref: FMA:293882
xref: MAT:0000069
xref: MESH:D054259 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: MIAA:0000069
xref: NCIT:C34226
xref: neuronames:1365
xref: SCTID:362852000
xref: TAO:0001135
xref: UMLS:C0231024 {source="ncithesaurus:Neural_Tube"}
xref: VHOG:0000307
xref: Wikipedia:Neural_tube
xref: XAO:0003204
xref: ZFA:0001135
is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
is_a: UBERON:0016879 ! future central nervous system
relationship: develops_from UBERON:0005068 ! neural rod
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI
property_value: UBPROP:0000001 "Hollow epithelial tube on dorsal side of the embryo that develops into the central nervous system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010617", ontology="AAO", source="AAO:JOR"}
property_value: UBPROP:0000001 "The dorsal tubular structure in the vertebrate embryo that develops into the brain and spinal cord. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000307", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/neural+tube"}
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000307", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium" xsd:string {source="GO:0021915"}

[Term]
id: UBERON:0001052
name: rectum
namespace: uberon
def: "The terminal portion of the intestinal tube, terminating with the anus." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MP:0000492]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "intestinum rectum" RELATED [BTO:0001158]
synonym: "rectal sac" RELATED []
synonym: "terminal portion of intestine" EXACT []
synonym: "terminal portion of large intestine" RELATED []
xref: AAO:0010401
xref: BTO:0001158
xref: CALOHA:TS-1180
xref: EFO:0000848
xref: EHDAA2:0001592
xref: EHDAA:5836
xref: EMAPA:17896
xref: EV:0100081
xref: FMA:14544
xref: GAID:311
xref: galen:Rectum
xref: MA:0000336
xref: MAT:0000050
xref: MESH:D012007
xref: MIAA:0000050
xref: NCIT:C12390
xref: SCTID:181261002
xref: UMLS:C0034896 {source="ncithesaurus:Rectum"}
xref: VHOG:0001751
xref: Wikipedia:Rectum
xref: XAO:0000238
is_a: UBERON:0004921 {order="4", source="cjm"} ! subdivision of digestive tract
relationship: continuous_with UBERON:0001159 ! sigmoid colon
relationship: contributes_to_morphology_of UBERON:0000059 ! large intestine
relationship: distalmost_part_of UBERON:0000059 {source="ISBN:0073040584"} ! large intestine
relationship: part_of UBERON:0000059 {source="MA"} ! large intestine
relationship: part_of UBERON:0006866 ! terminal part of digestive tract
relationship: part_of UBERON:0012361 {source="EHDAA2"} ! internal anal region
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/75/Anorectum.gif" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The terminal portion of the large intestine between the ileo-pelvic colon and the anus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001751", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "rectal" xsd:string
property_value: UBPROP:0000008 "In the lungfish, sharks and rays the rectum opens into the cloaca which also receives wastes (urine) from the kidneys and material from the reproductive organs. In bony fish the rectum reaches the outside environment through the anus, which is normally situated just in front the urinary and reproductive openings. However in some fish the digestive tract may be curled back on itself, and in the Electric Eel (Electrophorus electricus) the anus is situated in the fish's throat. -- http://www.earthlife.net/fish/digestion.html" xsd:string

[Term]
id: UBERON:0001062
name: anatomical entity
namespace: uberon
def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [FMA:62955, http://orcid.org/0000-0001-9114-8737]
subset: common_anatomy
subset: upper_level
xref: AAO:0010841
xref: AEO:0000000
xref: BFO:0000004
xref: BILA:0000000
xref: BIRNLEX:6
xref: CARO:0000000
xref: EHDAA2:0002229
xref: FBbt:10000000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:62955
xref: HAO:0000000
xref: MA:0000001
xref: NCIT:C12219
xref: TAO:0100000
xref: TGMA:0001822
xref: UMLS:C1515976 {source="ncithesaurus:Anatomic_Structure_System_or_Substance"}
xref: WBbt:0000100
xref: XAO:0000000
xref: ZFA:0100000
is_a: BFO:0000004 ! independent continuant
relationship: part_of UBERON:0003942 {gci_filler="GO:0050975", gci_relation="capable_of_part_of"} ! somatosensory system
relationship: part_of UBERON:0003942 {gci_relation="capable_of_part_of", gci_filler="GO:0019233"} ! somatosensory system
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0001064
name: ventral pancreatic duct
namespace: uberon
alt_id: UBERON:0005627
def: "A duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla." [Wikipedia:Pancreatic_duct]
comment: EDITOR_NOTE in EHDAA2 this is an epithelium, in FMA the wall consists of epithelium and connective tissue
subset: human_reference_atlas
subset: uberon_slim
synonym: "canal of Wirsung" RELATED [BTO:0002362]
synonym: "chief pancreatic duct" EXACT [FMA:16003]
synonym: "duct of Wirsung" EXACT [Wikipedia:Pancreatic_duct]
synonym: "ductus pancreatis ventralis" RELATED []
synonym: "hepaticopancreatic duct" RELATED [BTO:0002362]
synonym: "main pancreatic duct" EXACT [MA:0000126]
synonym: "pancreatic duct" BROAD [MESH:A03.734.667]
xref: BTO:0002362
xref: EHDAA2:0001396
xref: EHDAA:6905
xref: EMAPA:17510
xref: FMA:16003
xref: GAID:337
xref: MA:0000126
xref: MESH:D010183
xref: NCIT:C12272
xref: RETIRED_EHDAA2:0002177
xref: SCTID:245385001
xref: UMLS:C0030288 {source="ncithesaurus:Pancreatic_Duct"}
xref: VHOG:0000256
xref: Wikipedia:Pancreatic_duct
is_a: UBERON:0000025 ! tube
is_a: UBERON:0007329 {source="FMA"} ! pancreatic duct
relationship: channel_for UBERON:0001970 ! bile
relationship: channels_into UBERON:0004913 ! hepatopancreatic ampulla
relationship: continuous_with UBERON:0001174 ! common bile duct
relationship: develops_from UBERON:0003924 {source="EHDAA2"} ! ventral pancreatic bud
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "These data show that ducts within the zebrafish pancreas originally arise in situ from isolated progenitor cells rather than arising from reiterative branching of the pancreatic epithelium. This process of pancreatic duct formation in zebrafish may be analogous to the mechanism of duct formation in the mammalian mammary and salivary glands. (...) A related mechanism of duct formation has also been proposed to occur within the mammalian pancreatic epithelium.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000256", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.04.035 Yee NS, Lorent K, Pack M, Exocrine pancreas development in zebrafish. Developmental Biology (2005)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "Upon reaching its final destination, the ventral pancreatic bud fuses with the much larger dorsal pancreatic bud. At this point of fusion, the main ducts of the ventral and dorsal pancreatic buds fuse, forming the duct of Wirsung, the main pancreatic duct." xsd:string {source="WP"}

[Term]
id: UBERON:0001068
name: skin of back
namespace: uberon
def: "A zone of skin that is part of a back [Automatically generated definition]." [OBOL:automatic]
comment: EDITOR_NOTE TODO - distinguish between entire skin of region and arbitrary zone of skin on region
subset: pheno_slim
synonym: "back skin" EXACT []
synonym: "back zone of skin" EXACT [OBOL:automatic]
synonym: "skin, dorsal region" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "zone of skin of back" EXACT [OBOL:automatic]
xref: EMAPA:36392
xref: FMA:10462
xref: FMA:22985
xref: MA:0000498
xref: SCTID:181492002
is_a: UBERON:0001085 {source="MA"} ! skin of trunk
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0001137 ! dorsum
relationship: part_of UBERON:0011270 {source="MA"} ! dorsal trunk

[Term]
id: UBERON:0001070
name: external carotid artery
namespace: uberon
def: "A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP]." [MGI:anna]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "arteria carotis externa" RELATED OMO:0003011 [Wikipedia:External_carotid_artery]
synonym: "external carotid" EXACT [AAO:0010218]
xref: AAO:0010218
xref: AAO:0010416
xref: BTO:0004696
xref: EFO:0001953
xref: EHDAA2:0000461
xref: EMAPA:18611
xref: FMA:10635
xref: GAID:480
xref: MA:0001929
xref: MESH:D002342
xref: NCIT:C32551
xref: SCTID:362044002
xref: UMLS:C0007275 {source="ncithesaurus:External_Carotid_Artery"}
xref: VHOG:0000265
xref: Wikipedia:External_carotid_artery
xref: XAO:0000345
is_a: UBERON:0005396 {source="MA"} ! carotid artery segment
relationship: branching_part_of UBERON:0001530 {source="FMA"} ! common carotid artery plus branches
relationship: develops_from UBERON:0001530 {source="EHDAA2"} ! common carotid artery plus branches
relationship: part_of UBERON:0001530 {source="FMA"} ! common carotid artery plus branches
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/13/External_carotid_a.gif" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: seeAlso "https://sourceforge.net/tracker/?func=detail&aid=3486863&group_id=76834&atid=1127722" xsd:anyURI
property_value: UBPROP:0000008 "not homologous to the external carotid of zebrafish (Goodrich, 1958) - http://zfish.nichd.nih.gov/zfatlas/Intro%20Page/comparative.html; check XAO" xsd:string

[Term]
id: UBERON:0001071
name: superficial cervical artery
namespace: uberon
def: "It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery." [Wikipedia:Superficial_part_of_transverse_cervical_artery]
comment: The transverse cervical artery splits into two branches, a superficial one and a deep one[WP]
subset: human_reference_atlas
subset: uberon_slim
synonym: "superficial branch of transverse cervical artery" EXACT [Wikipedia:Superficial_part_of_transverse_cervical_artery]
xref: EMAPA:37117 {source="MA:th"}
xref: FMA:10665
xref: MA:0002052
xref: NCIT:C53005
xref: SCTID:161746006
xref: UMLS:C0226271 {source="ncithesaurus:Superficial_Cervical_Artery"}
xref: Wikipedia:Superficial_part_of_transverse_cervical_artery
is_a: UBERON:0012320 ! cervical artery
intersection_of: UBERON:0012320 ! cervical artery
intersection_of: part_of UBERON:0035549 ! vasculature of integument
relationship: connected_to UBERON:0012324 ! transverse cervical artery
relationship: part_of UBERON:0035549 ! vasculature of integument
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001072
name: posterior vena cava
namespace: uberon
def: "A vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Inferior_vena_cava]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "caudal vena cava" RELATED [VHOG:0001194]
synonym: "inferior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "inferior vena cava" EXACT [Wikipedia:Venae_cavae]
synonym: "postcava" RELATED []
synonym: "posterior vena cava" EXACT [Wikipedia:Venae_cavae]
synonym: "vena cava inferior" RELATED OMO:0003011 [BTO:0002682, Wikipedia:Inferior_vena_cava]
xref: AAO:0011083
xref: BTO:0002682
xref: EHDAA2:0000611
xref: EMAPA:18416
xref: FMA:10951
xref: GAID:548
xref: galen:InferiorVenaCava
xref: MA:0000480
xref: MESH:D014682
xref: NCIT:C12815
xref: SCTID:181369003
xref: UMLS:C0042458 {source="ncithesaurus:Inferior_Vena_Cava"}
xref: VHOG:0001194
xref: Wikipedia:Inferior_vena_cava
xref: XAO:0000388
is_a: UBERON:0004087 ! vena cava
intersection_of: UBERON:0004087 ! vena cava
intersection_of: drains UBERON:0000154 ! posterior region of body
disjoint_from: UBERON:0001585 {source="lexical"} ! anterior vena cava
relationship: channels_into UBERON:0002078 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! right cardiac atrium
relationship: connected_to UBERON:0002078 ! right cardiac atrium
relationship: develops_from UBERON:0005487 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="Wikipedia:Vitelline_vein"} ! vitelline vein
relationship: drains UBERON:0000154 ! posterior region of body
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray577.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Trunk of systemic vein which is formed by the union of the right common iliac vein and the left common iliac vein and terminates in the right atrium[FMA]." xsd:string {source="FMA:10951"}
property_value: UBPROP:0000003 "Phylogenetic modifications within this basic pattern of arteries and veins are largely correlated with functional changes. In the transition from water to land, gills gave way to lungs, accompanied by the establishment of a pulmonary circulation. In some fishes and certainly in tetrapods, the cardinal veins become less involved in blood return. Instead, the composite, prominent postcava (posterior vena cava) arose to drain the posterior part of the body and the precava (anterior vena cava) developed to drain the anterior part of the body.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001194", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.454-455", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001073
name: ileocecal junction
namespace: uberon
def: "A point along the course of the gastrointestinal tract where the small intestine (ileum) ends as it opens into the cecal portion of the large intestine; occurs usually within the iliac fossa, demarcated internally as the ileocecal orifice." [http://www.medilexicon.com/medicaldictionary.php?t=46539]
synonym: "ileocaecal junction" EXACT []
xref: EMAPA:37601 {source="MA:th"}
xref: FMA:11338
xref: MA:0000332
xref: SCTID:264021000
is_a: UBERON:8410024 ! intestinal junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0000059 ! large intestine
intersection_of: connects UBERON:0002108 ! small intestine
relationship: connects UBERON:0000059 ! large intestine
relationship: connects UBERON:0002108 ! small intestine
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>

[Term]
id: UBERON:0001074
name: pericardial cavity
namespace: uberon
def: "A potential space between the visceral and parietal layers of the pericardium." [Wikipedia:Pericardium]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cavitas pericardiaca" RELATED OMO:0003011 [Wikipedia:Pericardial_cavity]
synonym: "cavity of pericardial sac" EXACT []
synonym: "pericardial space" EXACT [Wikipedia:Pericardial_cavity]
xref: BSA:0000091
xref: EHDAA2:0001434
xref: EMAPA:16131
xref: EMAPA:16132
xref: FMA:11350
xref: galen:PericardialSpace
xref: MA:0000053
xref: NCIT:C38662
xref: SCTID:362027001
xref: TAO:0002220
xref: UMLS:C0225972 {source="ncithesaurus:Pericardial_Cavity"}
xref: VHOG:0000556
xref: Wikipedia:Pericardial_cavity
xref: ZFA:0001655
is_a: UBERON:0002323 {source="MA"} ! coelemic cavity lumen
is_a: UBERON:0035809 ! serous cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0002406 ! pericardial sac
relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom
relationship: location_of UBERON:0002409 ! pericardial fluid
relationship: luminal_space_of UBERON:0002406 ! pericardial sac
relationship: part_of UBERON:0002406 {source="FMA"} ! pericardial sac
relationship: surrounded_by UBERON:0002357 ! serous pericardium
property_value: UBPROP:0000001 "Anatomical space in which the heart is located and is surrounded by the pericardium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002220", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart (of other tetrapods) is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes). Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000556", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "check ZFA, should actually be thoracic cavity. Note that Hyman defines the cavity as the space between the heart and the sac (but defines the sac as parietal)" xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0001081
name: endocardium of ventricle
namespace: uberon
def: "Endocardium that is part of the cardiac ventricle." [ZFIN:curator]
subset: pheno_slim
subset: vertebrate_core
synonym: "cardiac ventricle endocardium" EXACT [OBOL:automatic]
synonym: "endocardium of cardiac ventricle" EXACT [OBOL:automatic]
synonym: "endocardium of heart ventricle" EXACT [OBOL:automatic]
synonym: "endocardium of lower chamber of heart" EXACT [OBOL:automatic]
synonym: "endocardium of ventricle of heart" EXACT [OBOL:automatic]
synonym: "heart ventricle endocardium" EXACT [OBOL:automatic]
synonym: "lower chamber of heart endocardium" EXACT [OBOL:automatic]
synonym: "ventricle endocardial tissue" RELATED [VHOG:0000607]
synonym: "ventricle endocardium" EXACT []
synonym: "ventricle of heart endocardium" EXACT [OBOL:automatic]
synonym: "ventricular endocardium" EXACT []
xref: EMAPA:32747
xref: FMA:12148
xref: MA:0000079
xref: SCTID:192172004
xref: TAO:0002247
xref: VHOG:0000607
xref: ZFA:0001615
is_a: UBERON:0000487 ! simple squamous epithelium
is_a: UBERON:0002165 ! endocardium
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0002165 ! endocardium
intersection_of: part_of UBERON:0002082 ! cardiac ventricle
relationship: contributes_to_morphology_of UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0004784 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! heart ventricle wall

[Term]
id: UBERON:0001082
name: epicardium of ventricle
namespace: uberon
def: "An epicardial layer that lines a cardiac ventricle." [http://orcid.org/0000-0002-6601-2165]
subset: vertebrate_core
synonym: "cardiac ventricle epicardium" EXACT [OBOL:automatic]
synonym: "ventricular epicardium" EXACT []
xref: FMA:12150
xref: TAO:0005058
xref: ZFA:0005058
is_a: UBERON:0002348 ! epicardium
intersection_of: UBERON:0002348 ! epicardium
intersection_of: part_of UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0002082 ! cardiac ventricle
property_value: UBPROP:0000001 "The external layer of the ventricle bounding the ventricular myocardium. It is formed by a single layer of mesothelial cells supported by a basal lamina, and imbricated with collagen, fibroblasts, and vascular structures in the subepicardial space. Hu et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005058", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0001083
name: myocardium of ventricle
namespace: uberon
def: "Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer." [ZFIN:curator]
subset: efo_slim
subset: pheno_slim
subset: vertebrate_core
synonym: "ventricle cardiac muscle" RELATED [VHOG:0000604]
synonym: "ventricle myocardium" EXACT []
synonym: "ventricular myocardium" EXACT []
xref: EFO:0003088
xref: EMAPA:32748
xref: FMA:12151
xref: MA:0000082
xref: SCTID:192084000
xref: TAO:0005061
xref: VHOG:0000604
xref: ZFA:0005061
is_a: UBERON:0002349 ! myocardium
intersection_of: UBERON:0002349 ! myocardium
intersection_of: part_of UBERON:0002082 ! cardiac ventricle
relationship: contributes_to_morphology_of UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0004784 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! heart ventricle wall
property_value: UBPROP:0000001 "Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer Hu et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005061", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000604", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001084
name: skin of head
namespace: uberon
def: "A zone of skin that is part of a head [Automatically generated definition]." [OBOL:automatic]
comment: EDITOR_NOTE TODO - distinguish between entire skin of region and arbitrary zone of skin on region
synonym: "adult head zone of skin" EXACT [OBOL:automatic]
synonym: "head skin" EXACT []
synonym: "head zone of skin" EXACT [OBOL:automatic]
synonym: "zone of skin of adult head" EXACT [OBOL:automatic]
synonym: "zone of skin of head" EXACT [OBOL:automatic]
xref: FMA:12166
xref: FMA:24756
xref: MA:0000582
xref: NCIT:C52757
xref: SCTID:181484006
xref: UMLS:C0205029 {source="ncithesaurus:Head_Skin"}
is_a: UBERON:0012180 ! head or neck skin
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0000033 ! head

[Term]
id: UBERON:0001085
name: skin of trunk
namespace: uberon
def: "A zone of skin that is part of a trunk [Automatically generated definition]." [OBOL:automatic]
comment: EDITOR_NOTE TODO - distinguish between entire skin of region and arbitrary zone of skin on region
synonym: "torso zone of skin" EXACT [OBOL:automatic]
synonym: "trunk skin" EXACT []
synonym: "trunk zone of skin" EXACT [OBOL:automatic]
synonym: "zone of skin of torso" EXACT [OBOL:automatic]
synonym: "zone of skin of trunk" EXACT [OBOL:automatic]
xref: EMAPA:37278 {source="MA:th"}
xref: FMA:12167
xref: FMA:23093
xref: MA:0000517
xref: NCIT:C12295
xref: SCTID:181489001
xref: UMLS:C0205031 {source="ncithesaurus:Skin_of_the_Trunk"}
is_a: UBERON:0000014 ! zone of skin
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk

[Term]
id: UBERON:0001087
name: pleural fluid
namespace: uberon
def: "Transudate contained in the pleural cavity." [FMA:12273]
subset: uberon_slim
xref: BTO:0003080
xref: FMA:12273
xref: MA:0002532
xref: MAT:0000500
xref: ncithesaurus:Pleural_Fluid
xref: Wikipedia:Pleural_fluid
is_a: UBERON:0036244 ! secretion of serous membrane
intersection_of: UBERON:0007779 ! transudate
intersection_of: located_in UBERON:0002402 ! pleural cavity
relationship: located_in UBERON:0002402 ! pleural cavity

[Term]
id: UBERON:0001088
name: urine
namespace: uberon
def: "Excretion that is the output of a kidney." [https://github.com/geneontology/go-ontology/issues/11025, Wikipedia:Urine]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
xref: BTO:0001419
xref: CALOHA:TS-1092
xref: EFO:0001939
xref: EMAPA:36554
xref: ENVO:00002047
xref: FMA:12274
xref: GAID:1189
xref: galen:Urine
xref: MA:0002545
xref: MAT:0000058
xref: MESH:D014556
xref: MIAA:0000058
xref: NCIT:C13283
xref: UMLS:C0042036 {source="ncithesaurus:Urine"}
xref: Wikipedia:Urine
is_a: UBERON:0000174 ! excreta
intersection_of: UBERON:0000174 ! excreta
intersection_of: produced_by UBERON:0002113 ! kidney
relationship: has_quality PATO:0001548 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! quality of a liquid
relationship: produced_by UBERON:0002113 ! kidney
property_value: UBPROP:0000008 "kidney excreta from some taxa (e.g. in aves) may not be liquid" xsd:string

[Term]
id: UBERON:0001090
name: synovial fluid
namespace: uberon
def: "Joint fluid is a transudate of plasma that is actively secreted by synovial cells." [https://www.ncbi.nlm.nih.gov/books/NBK274/]
subset: uberon_slim
subset: vertebrate_core
synonym: "joint fluid" EXACT [https://www.ncbi.nlm.nih.gov/books/NBK274/]
xref: BTO:0001339
xref: CALOHA:TS-0996
xref: ENVO:02000039
xref: FMA:12277
xref: GAID:265
xref: galen:SynovialFluid
xref: MA:0002544
xref: MESH:D013582
xref: NCIT:C33718
xref: TAO:0005154
xref: UMLS:C0039097 {source="ncithesaurus:Synovial_Fluid"}
xref: Wikipedia:Synovial_fluid
xref: ZFA:0005154
is_a: UBERON:0007779 ! transudate
is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland
intersection_of: UBERON:0007779 ! transudate
intersection_of: produced_by CL:0000214 ! synovial cell
relationship: has_part CHEBI:16336 ! hyaluronic acid
relationship: located_in UBERON:0007617 ! synovial cavity of joint
relationship: produced_by CL:0000214 ! synovial cell
property_value: UBPROP:0000001 "Portion of organism substance that is a clear fluid that occupies the space in synovial joints.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005154", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000009 "It provides nutrients and lubrication for articular cartilage" xsd:string
property_value: UBPROP:0000010 "The fluid contains hyaluronan secreted by fibroblast-like cells in the synovial membrane, lubricin (proteoglycan 4; PRG4) secreted by the surface chondrocytes of the articular cartilage and interstitial fluid filtered from the blood plasma" xsd:string

[Term]
id: UBERON:0001092
name: vertebral bone 1
namespace: uberon
def: "The first vertebral bone in the vertebral column." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "atlas" EXACT []
synonym: "atlas (CI)" EXACT []
synonym: "atlas [C I]" EXACT OMO:0003011 [FMA:12519, FMA:TA]
synonym: "atlas vertebra" EXACT []
synonym: "C1" BROAD []
synonym: "C1 vertebra" EXACT []
synonym: "cervical atlas" EXACT [MP:0011576]
synonym: "cervical vertebra 1" EXACT HUMAN_PREFERRED [MA:0001421]
synonym: "first cervical vertebra" EXACT []
synonym: "vertebra 1" EXACT [TAO:0001167]
xref: AAO:0000709
xref: EHDAA:10606
xref: EMAPA:19431
xref: FMA:12519
xref: GAID:236
xref: MA:0001421
xref: MESH:D001270
xref: NCIT:C32239
xref: SCTID:181818007
xref: TAO:0001167
xref: UMLS:C0004170 {source="ncithesaurus:C1_Vertebra"}
xref: Wikipedia:Atlas_(anatomy)
xref: ZFA:0001167
is_a: UBERON:0002412 ! vertebra
relationship: anterior_to UBERON:0001093 ! vertebral bone 2
relationship: anteriorly_connected_to UBERON:0001676 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! occipital bone
relationship: part_of UBERON:0006072 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! cervical region of vertebral column
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "First postcranial vertebra, which is modified anteriorly to articulate with the skull.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000709", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"}
property_value: UBPROP:0000001 "Vertebra that is posteriorly adjacent to the neurocranium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001167", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000107 "1" xsd:nonNegativeInteger

[Term]
id: UBERON:0001093
name: vertebral bone 2
namespace: uberon
def: "The second vertebral bone in the vertebral column." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "axis" RELATED INCONSISTENT [MA:0001422]
synonym: "axis (CII)" EXACT []
synonym: "axis [C II]" EXACT OMO:0003011 [FMA:12520, FMA:TA]
synonym: "axis vertebra" EXACT []
synonym: "C2" RELATED []
synonym: "C2 vertebra" NARROW []
synonym: "cervical axis" EXACT [MP:0004608]
synonym: "cervical vertebra 2" NARROW HUMAN_PREFERRED [MA:0001422]
synonym: "second cervical vertebra" NARROW []
synonym: "vertebra 2" EXACT [ZFA:0001168]
xref: EHDAA:10608
xref: EMAPA:19432
xref: FMA:12520
xref: GAID:237
xref: MA:0001422
xref: MESH:D001368
xref: NCIT:C32240
xref: SCTID:181819004
xref: TAO:0001168
xref: UMLS:C0004457 {source="ncithesaurus:C2_Vertebra"}
xref: Wikipedia:Axis_(anatomy)
xref: ZFA:0001168
is_a: UBERON:0002412 ! vertebra
relationship: anteriorly_connected_to UBERON:0001092 {source="FMA"} ! vertebral bone 1
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0006072 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! cervical region of vertebral column
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Vertebra that is posteriorly adjacent to vertebra 1.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001168", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000013 "not the same as ZFA term 'axis'" xsd:string
property_value: UBPROP:0000107 "2" xsd:nonNegativeInteger

[Term]
id: UBERON:0001095
name: caudal vertebra
namespace: uberon
alt_id: UBERON:0006070
def: "Any vertebral bone that is part of the caudal region of the vertebral column (tail or coccyx)." [http://orcid.org/0000-0002-6601-2165]
comment: Taxon notes In zebrafish, Vertebra bearing a hemal arch and spine. The most posterior caudal vertebrae support the caudal fin and are referred to as preural vertebrae
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "caudal vertebra" BROAD SENSU [FMA:12527]
synonym: "caudal vertebrae" EXACT OMO:0003004 []
synonym: "caudal vertebral bone" EXACT []
synonym: "caudal vertebral bone element" EXACT []
synonym: "coccygea" RELATED [MA:0001420]
synonym: "coccygeal segment" EXACT []
synonym: "coccygeal vertebra" EXACT [FMA:12527]
synonym: "fused tail vertebra" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "tail vertebra" RELATED [MA:0000310]
xref: EMAPA:18374
xref: FMA:12527
xref: galen:CoccygealVertebra
xref: MA:0000310
xref: MA:0001420
xref: NCIT:C32334
xref: SCTID:361774004
xref: TAO:0000326
xref: UMLS:C0223616 {source="ncithesaurus:Coccygeal_Vertebra"}
xref: Wikipedia:Caudal_vertebra
xref: XAO:0003079
xref: ZFA:0000326
is_a: UBERON:0002412 ! vertebra
is_a: UBERON:0004247 ! bone of dorsum
is_a: UBERON:0018142 ! caudal vertebra endochondral element
intersection_of: UBERON:0018142 ! caudal vertebra endochondral element
intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Vertebrae bearing a hemal arch and spine. The most posterior caudal vertebrae support the caudal fin and are referred to as preural vertebrae.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000326", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000012 "we deliberately merge the MA classes as we believe them equivalent" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001096
name: wall of esophagus
namespace: uberon
def: "An anatomical wall that is part of a esophagus [Automatically generated definition]." [OBOL:automatic]
synonym: "anatomical wall of esophagus" EXACT [OBOL:automatic]
synonym: "anatomical wall of gullet" EXACT [OBOL:automatic]
synonym: "anatomical wall of oesophagus" EXACT [OBOL:automatic]
synonym: "esophageal wall" EXACT []
synonym: "esophagus anatomical wall" EXACT [OBOL:automatic]
synonym: "esophagus wall" EXACT []
synonym: "gullet anatomical wall" EXACT [OBOL:automatic]
synonym: "gullet wall" EXACT [OBOL:automatic]
synonym: "oesophagus anatomical wall" EXACT [OBOL:automatic]
synonym: "oesophagus wall" EXACT [OBOL:automatic]
synonym: "wall of gullet" EXACT [OBOL:automatic]
synonym: "wall of oesophagus" EXACT [OBOL:automatic]
xref: EMAPA:35326
xref: FMA:12611
xref: MA:0002691
is_a: UBERON:0000328 ! gut wall
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001043 ! esophagus

[Term]
id: UBERON:0001103
name: diaphragm
namespace: uberon
def: "A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control." [MP:0002279]
subset: efo_slim
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "diaphragm muscle" EXACT [BTO:0000341]
synonym: "diaphragm of thorax" EXACT []
synonym: "midriff" RELATED [BTO:0000341]
synonym: "phren" RELATED [BTO:0000341]
synonym: "thoracic diaphragm" EXACT []
xref: BTO:0000341
xref: CALOHA:TS-0198
xref: EFO:0000937
xref: EHDAA2:0003495
xref: EMAPA:17701
xref: EV:0100376
xref: FMA:13295
xref: GAID:158
xref: MA:0001904
xref: MAT:0000502
xref: MESH:D003964
xref: NCIT:C12702
xref: SCTID:181614006
xref: UMLS:C0011980 {source="ncithesaurus:Diaphragm"}
xref: VHOG:0000713
xref: Wikipedia:Thoracid_diaphragm
is_a: UBERON:0003830 ! thoracic segment muscle
is_a: UBERON:0003831 ! respiratory system muscle
relationship: develops_from UBERON:0010084 ! future diaphragm
relationship: immediate_transformation_of UBERON:0010084 {evidence="definitional"} ! future diaphragm
relationship: innervated_by UBERON:0001884 ! phrenic nerve
relationship: only_in_taxon NCBITaxon:40674 {source="PMID:23586979"} ! Mammalia
property_value: RO:0002161 NCBITaxon:8782 {source="Wikipedia:Thoracic_diaphragm#Comparative_anatomy_and_evolution"}
property_value: UBPROP:0000001 "The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs[GO]." xsd:string {source="GO:0060539"}
property_value: UBPROP:0000003 "The mammals are characterized by a diaphragm, which separates the thoracic portion of the body cavity from the abdominal region and assists in drawing air into the lungs and forcing it out. Modern reptiles lack a muscular diaphragm and it is reasonable to suppose that the diaphragm developed as a new device that made possible a large degree of oxygen intake for active animals. The change may have taken place during the transition from reptile to mammal (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000713", ontology="VHOG", source="ISBN:978-0471384618 Colbert EH, Evolution of the vertebrates: a history of the backboned animals through time (2001) p.278", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "phrenic" xsd:string
property_value: UBPROP:0000008 "The existence of some membrane separating the pharynx from the stomach can be traced widely among the chordates. Thus amphioxus possesses an atrium by which water exits the pharynx, which has been argued (and disputed) to be homologous to structures in ascidians and hagfishes.[3]" xsd:string
property_value: UBPROP:0000008 "The urochordate epicardium separates digestive organs from the pharynx and heart, but the anus returns to the upper compartment to discharge wastes through an outgoing siphon (Thoracic_diaphragm#Comparative_anatomy_and_evolution)" xsd:string
property_value: UBPROP:0000009 "barrier between thoracic and abdominal cavities; stop gastric contents from refluxing into the oesophagus" xsd:string
property_value: UBPROP:0000009 "breathing control" xsd:string
property_value: UBPROP:0000011 "originate from the cervical somites, likely C3-C5[PMID:23586979]" xsd:string

[Term]
id: UBERON:0001113
name: lobe of liver
namespace: uberon
def: "Traditional gross anatomy divided the liver into four lobes based on surface features. The falciform ligament is visible on the front (anterior side) of the liver. This divides the liver into a left anatomical lobe, and a right anatomical lobe." [Wikipedia:Liver#Lobes]
synonym: "hepatic lobe" EXACT []
synonym: "liver lobe" EXACT []
synonym: "lobus hepatis" EXACT []
xref: EMAPA:18306
xref: FMA:13361
xref: MA:0000360
xref: NCIT:C49579
xref: SCTID:245378000
xref: UMLS:C0447541 {source="ncithesaurus:Liver_Lobe"}
xref: Wikipedia:Liver#Lobes
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0009912 {source="FMA"} ! anatomical lobe
relationship: part_of UBERON:0002107 ! liver
property_value: editor_note "some work needs to be done to ensure the child terms of this class have correct isa/partof placement. in MA they are subclasses, in FMA they are parts" xsd:string

[Term]
id: UBERON:0001114
name: right lobe of liver
namespace: uberon
def: "The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]." [Wikipedia:Right_lobe_of_liver]
subset: uberon_slim
subset: vertebrate_core
synonym: "2nd lobe" RELATED [TAO:0005173]
synonym: "gall bladder lobe" RELATED SENSU [ZFA:0005173]
synonym: "liver right lobe" EXACT []
synonym: "lobus hepaticus dexter" EXACT OMO:0003011 []
synonym: "lobus hepatis dexter" RELATED OMO:0003011 [Wikipedia:Right_lobe_of_liver]
synonym: "right hepatic lobe" RELATED [EMAPA:18311]
synonym: "right liver lobe" EXACT [ZFA:0005173]
synonym: "second lobe" RELATED [TAO:0005173]
xref: EHDAA2:0001008
xref: EHDAA:4001
xref: EMAPA:18311
xref: FMA:13362
xref: MA:0000363
xref: NCIT:C33481
xref: SCTID:362182008
xref: TAO:0005173
xref: UMLS:C0227481 {source="ncithesaurus:Right_Lobe_of_the_Liver"}
xref: VHOG:0001424
xref: Wikipedia:Right_lobe_of_liver
xref: ZFA:0005173
is_a: UBERON:0001113 ! lobe of liver
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray1087-liver.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Liver.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Liver.glb" xsd:anyURI
property_value: UBPROP:0000001 "Portion of the liver which develops on the fish's right side adjacent to the gall bladder.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005173", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0001115
name: left lobe of liver
namespace: uberon
def: "The left lobe is smaller and more flattened than the right. It is situated in the epigastric and left hypochondriac regions. Its upper surface is slightly convex and is moulded on to the diaphragm; its under surface presents the gastric impression and omental tuberosity. [WP,unvetted]." [Wikipedia:Left_lobe_of_liver]
subset: uberon_slim
subset: vertebrate_core
synonym: "left hepatic lobe" RELATED [EMAPA:18307]
synonym: "left liver lobe" EXACT []
synonym: "liver left lobe" EXACT []
synonym: "lobus hepaticus sinister" EXACT OMO:0003011 []
synonym: "lobus hepatis sinister" RELATED OMO:0003011 [Wikipedia:Left_lobe_of_liver]
xref: EHDAA2:0001000
xref: EHDAA:3995
xref: EMAPA:18307
xref: FMA:13363
xref: MA:0000361
xref: NCIT:C32965
xref: SCTID:362183003
xref: TAO:0005172
xref: UMLS:C0227486 {source="ncithesaurus:Left_Lobe_of_the_Liver"}
xref: VHOG:0001423
xref: Wikipedia:Left_lobe_of_liver
xref: ZFA:0005172
is_a: UBERON:0001113 ! lobe of liver
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray1087-liver.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Liver.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Liver.glb" xsd:anyURI
property_value: UBPROP:0000001 "Portion of the liver which develops on the fish's left side.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005172", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0001130
name: vertebral column
namespace: uberon
def: "Subdivision of skeletal system that consists of all the vertebra and associated skeletal elements and joints in the body[modified from VSAO]." [https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/?func=detail&aid=3530322&group_id=76834&atid=2257941, VSAO:0000185]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "backbone" NARROW [FMA:13478]
synonym: "columna vertebralis" RELATED [BTO:0000818]
synonym: "dorsal spine" RELATED [BTO:0000818]
synonym: "spinal column" RELATED [MESH:A02.835.232.834]
synonym: "spine" BROAD [FMA:13478]
synonym: "vertebral column skeleton" NARROW [AAO:0000699]
synonym: "vertebral region" RELATED []
xref: AAO:0000699
xref: AAO:0000734
xref: BTO:0000818
xref: EFO:0001369
xref: EHDA:10119
xref: EMAPA:35919
xref: FMA:13478
xref: GAID:106
xref: galen:SpinalColumn
xref: MA:0002416
xref: MESH:D013131
xref: NCIT:C12998
xref: NCIT:C33588
xref: NIF_Subcellular:sao1145756102
xref: SCTID:44300000
xref: TAO:0001559
xref: UMLS:C0037949 {source="ncithesaurus:Vertebral_Column"}
xref: UMLS:C1519455 {source="ncithesaurus:Spinal_Cord_Column"}
xref: VHOG:0001142
xref: VSAO:0000185
xref: Wikipedia:Vertebral_column
xref: XAO:0003074
xref: ZFA:0001559
is_a: UBERON:0000075 ! subdivision of skeletal system
intersection_of: UBERON:0000075 ! subdivision of skeletal system
intersection_of: composed_primarily_of UBERON:0010913 ! vertebral element
relationship: composed_primarily_of UBERON:0010913 ! vertebral element
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0011138 {source="cjm"} ! postcranial axial skeletal system
relationship: protects UBERON:0002240 ! spinal cord
property_value: editor_note "Note that in contrast to VSAO, this is a subset of the skeletal system, and thus includes intervertebral joints, cartilage and ligaments etc. Some ontologies such as AAO seem to purely refer to the skeleton" xsd:string
property_value: RO:0002161 NCBITaxon:7762
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anatomical cluster that consists of all the vertebra in the body.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000185", ontology="VSAO", source="VSAO:curator"}
property_value: UBPROP:0000001 "The vertebral column consists of a series of vertebrae connected by ligaments. It provides a supporting axis for the body and protects the spinal cord. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001142", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/vertebral+column"}
property_value: UBPROP:0000003 "Vertebrata is characterized by three synapomorphies. First, vertebrates have a backbone composed of vertebrae (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001142", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.53", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001131
name: vertebral foramen
namespace: uberon
def: "A foramen within a vertebral element through which the spinal cord runs. It is formed by the anterior segment, and the posterior part, the vertebral arch." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Vertebral_foramen]
subset: uberon_slim
synonym: "foramen vertebrale" RELATED OMO:0003011 [Wikipedia:Vertebral_foramen]
synonym: "vertebra neural canal" EXACT []
xref: AAO:0000729
xref: EMAPA:37803 {source="MA:th"}
xref: FMA:13479
xref: MA:0001454
xref: SCTID:280734009
xref: Wikipedia:Vertebral_foramen
is_a: UBERON:0004111 ! anatomical conduit
intersection_of: UBERON:0004111 ! anatomical conduit
intersection_of: conduit_for UBERON:0002240 ! spinal cord
intersection_of: lumen_of UBERON:0010913 ! vertebral element
relationship: conduit_for UBERON:0002240 ! spinal cord
relationship: lumen_of UBERON:0010913 ! vertebral element
relationship: part_of UBERON:0006692 ! vertebral canal
relationship: part_of UBERON:0010913 ! vertebral element
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/10/Foramenvertebrale.png" xsd:anyURI
property_value: UBPROP:0000001 "Opening on the vertebra for a spinal nerve as it emerges from the spinal canal.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000729", ontology="AAO", source="AAO:LAP"}

[Term]
id: UBERON:0001133
name: cardiac muscle tissue
namespace: uberon
alt_id: UBERON:0007096
def: "Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified]." [ZFA:0005280]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cardiac muscle" EXACT []
synonym: "cardiac muscle muscle tissue" EXACT [OBOL:automatic]
synonym: "cardiac muscle textus muscularis" EXACT [OBOL:automatic]
synonym: "cardiac musculature" RELATED [BILA:0000134]
synonym: "heart muscle muscle tissue" EXACT [OBOL:automatic]
synonym: "heart muscle textus muscularis" EXACT [OBOL:automatic]
synonym: "heart myocardium muscle tissue" EXACT [OBOL:automatic]
synonym: "heart myocardium textus muscularis" EXACT [OBOL:automatic]
synonym: "muscle of heart muscle tissue" EXACT [OBOL:automatic]
synonym: "muscle of heart textus muscularis" EXACT [OBOL:automatic]
synonym: "muscle tissue of cardiac muscle" EXACT [OBOL:automatic]
synonym: "muscle tissue of heart muscle" EXACT [OBOL:automatic]
synonym: "muscle tissue of heart myocardium" EXACT [OBOL:automatic]
synonym: "muscle tissue of muscle of heart" EXACT [OBOL:automatic]
synonym: "muscle tissue of myocardium" EXACT [OBOL:automatic]
synonym: "myocardium muscle tissue" EXACT [OBOL:automatic]
synonym: "myocardium textus muscularis" EXACT [OBOL:automatic]
synonym: "textus muscularis of cardiac muscle" EXACT [OBOL:automatic]
synonym: "textus muscularis of heart muscle" EXACT [OBOL:automatic]
synonym: "textus muscularis of heart myocardium" EXACT [OBOL:automatic]
synonym: "textus muscularis of muscle of heart" EXACT [OBOL:automatic]
synonym: "textus muscularis of myocardium" EXACT [OBOL:automatic]
xref: AAO:0010245
xref: AEO:0000142
xref: BILA:0000134
xref: BTO:0000199
xref: CALOHA:TS-0440
xref: EHDAA2:0003142
xref: EMAPA:32688
xref: FMA:14068
xref: galen:CardiacMuscle
xref: galen:CardiacMuscleTissue
xref: ncithesaurus:Heart_Muscle
xref: TAO:0005280
xref: Wikipedia:Cardiac_muscle
xref: ZFA:0005280
is_a: UBERON:8600006 ! visceral striated muscle tissue
intersection_of: UBERON:0002036 ! striated muscle tissue
intersection_of: has_part CL:0000746 ! cardiac muscle cell
disjoint_from: UBERON:0001134 ! skeletal muscle tissue
relationship: composed_primarily_of CL:0000746 ! cardiac muscle cell
relationship: has_part CL:0000746 ! cardiac muscle cell
relationship: part_of UBERON:0007100 ! primary circulatory organ
property_value: editor_note "check relationship with myocardium. part_of in MA - but we also have a more specific class 'cardiac muscle tissue of myocardium'. Check ncit" xsd:string

[Term]
id: UBERON:0001134
name: skeletal muscle tissue
namespace: uberon
def: "Muscle tissue that consists primarily of skeletal muscle fibers." [https://github.com/obophenotype/uberon/issues/324]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "skeletal muscle" BROAD []
synonym: "skeletal muscle system" RELATED [BTO:0001103]
synonym: "somatic muscle" RELATED [BTO:0001103]
xref: EMAPA:32716
xref: FMA:14069
xref: MA:0002439
xref: NCIT:C13050
xref: SCTID:426215008
xref: UMLS:C0242692 {source="ncithesaurus:Skeletal_Muscle_Tissue"}
xref: Wikipedia:Skeletal_striated_muscle
is_a: UBERON:0002036 ! striated muscle tissue
intersection_of: UBERON:0002385 ! muscle tissue
intersection_of: composed_primarily_of CL:0008002 ! skeletal muscle fiber
relationship: composed_primarily_of CL:0008002 ! skeletal muscle fiber
relationship: develops_from UBERON:0003082 ! myotome
relationship: part_of UBERON:0014892 ! skeletal muscle organ, vertebrate
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/c/c0/Skeletal_muscle.jpg" xsd:anyURI
property_value: editor_note "TODO - add skeletal muscle organ? See GO:0060538 skeletal muscle organ development. Todo - group FBbt:00005073 - somatic muscle." xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/dosumis
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/RDruzinsky
property_value: UBPROP:0000001 "Muscle, composed of long cylindrical, multinucleated cells that attaches to the skeleton via tendons.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005277", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Tissue which consists of skeletal muscle fibers surrounded by endomysium. Examples: Skeletal muscle tissue of biceps, Skeletal muscle tissue of diaphragm[FMA]" xsd:string {external_class="FMA:14069", ontology="FMA"}
property_value: UBPROP:0000003 "This result implies the following views in terms of evolutionary differentiation: (1) Arthropod striated muscle and vertebrate skeletal and cardiac muscles share a common ancestor. In other words, they did not evolve independently (...) (5) The divergence of vertebrate skeletal and cardiac muscles/vertebrate smooth muscle and nonmuscle is at least before that of vertebrates/arthropods. In other words, emergence of skeletal and cardiac musle type tissues preceded the vertebrate/arthropod divergence (ca. 700 MYA).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000319", ontology="VHOG", source="PMID:10368962 Oota S, Saitou N, Phylogenetic relationship of muscle tissues deduced from superimposition of gene trees. Mol Biol Evol (1999)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001135
name: smooth muscle tissue
namespace: uberon
def: "Muscle tissue which is unstriated, composed primarily of smooth muscle fibers surrounded by a reticulum of collagen and elastic fibers. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length[GO]." [GO:0006939, Wikipedia:Smooth_muscle_tissue]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "involuntary muscle" EXACT []
synonym: "non-striated muscle" EXACT []
synonym: "smooth muscle" EXACT []
synonym: "textus muscularis levis; textus muscularis nonstriatus" RELATED OMO:0003011 [Wikipedia:Smooth_muscle_tissue]
synonym: "textus muscularis nonstriatus" EXACT OMO:0003011 [FMA:14070, FMA:TA]
synonym: "visceral muscle" NARROW SENSU []
synonym: "visceral muscle tissue" NARROW SENSU []
xref: AAO:0010244
xref: AEO:0000141
xref: BTO:0001260
xref: CALOHA:TS-0943
xref: EFO:0000889
xref: EHDAA2:0003141
xref: EMAPA:32717
xref: EV:0100378
xref: FMA:14070
xref: GAID:167
xref: galen:SmoothMuscle
xref: galen:SmoothMuscleTissue
xref: MA:0000166
xref: MAT:0000303
xref: MESH:D009130
xref: MIAA:0000303
xref: NCIT:C12437
xref: TAO:0005274
xref: UMLS:C1267092 {source="ncithesaurus:Smooth_Muscle_Tissue"}
xref: VHOG:0001246
xref: WBbt:0005781
xref: Wikipedia:Smooth_muscle_tissue
xref: XAO:0000175
xref: ZFA:0005274
is_a: UBERON:0002385 ! muscle tissue
intersection_of: UBERON:0002385 ! muscle tissue
intersection_of: has_part CL:0000192 ! smooth muscle cell
disjoint_from: UBERON:0002036 ! striated muscle tissue
relationship: composed_primarily_of CL:0000192 ! smooth muscle cell
relationship: has_part CL:0000192 ! smooth muscle cell
relationship: has_part GO:0071953 ! elastic fiber
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/3b/Glatte_Muskelzellen.jpg" xsd:anyURI
property_value: UBPROP:0000001 "A non-striated muscle that is composed of spindle-shaped cells. Smooth muscle usually is organized into sheets that line cavitated organs.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005274", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Involuntary muscle tissue consisting of uninucleate spindle-shaped fibers.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010244", ontology="AAO", source="AAO:CAM"}
property_value: UBPROP:0000003 "(...) the first bilateral animals possessed only smooth muscles with the molecular repertoire necessary to build a striated muscle. (...) it is more parsimonious to regard striated muscle cells as a sister cell type to the smooth muscle cells. In this scenario, striated and smooth muscles would have arisen in the stem lineage that led to the Nephrozoa (i.e. all Bilateria exclusive the acoelomorphs) (Hejnol et al., 2009), from an 'acoel-like' smooth muscle, by segregation and divergence of functions and through differential recruitment of additional genes[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001246", ontology="VHOG", source="DOI:10.1002/jez.b.21416 Chiodin M, Achatz JG, Wanninger A, Martinez P, Molecular architecture of muscles in an acoel and its evolutionary implications. Journal of Experimental Zoology (2011)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000013 "GO uses visceral and smooth interchangeably. However visceral can also be used in the sense of the viscera. Many fly annotations to smooth muscle terms. If we want to be inclusive of insects have to have a general definition of tissue that includes cells." xsd:string

[Term]
id: UBERON:0001136
name: mesothelium
namespace: uberon
def: "Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri)." [FMA:14074, Wikipedia:Mesothelium]
subset: uberon_slim
xref: AEO:0000111
xref: BTO:0002422
xref: CALOHA:TS-1183
xref: EHDAA2_RETIRED:0003111
xref: EHDAA:2331
xref: EHDAA:2349
xref: EHDAA:295
xref: EHDAA:6073
xref: EHDAA:640
xref: EHDAA:646
xref: EMAPA:32856
xref: FMA:14074
xref: MA:0000565
xref: NCIT:C33105
xref: SCTID:361918002
xref: UMLS:C0086610 {source="ncithesaurus:Mesothelium"}
xref: Wikipedia:Mesothelium
is_a: UBERON:0000487 ! simple squamous epithelium
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0000487 ! simple squamous epithelium
intersection_of: develops_from UBERON:0000926 ! mesoderm
intersection_of: part_of UBERON:0000042 ! serous membrane
relationship: composed_primarily_of CL:0000077 {source="FMA"} ! mesothelial cell
relationship: part_of UBERON:0000042 ! serous membrane
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg" xsd:anyURI

[Term]
id: UBERON:0001137
name: dorsum
namespace: uberon
def: "A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.." [BSPO:0000063, UBERONREF:0000006, Wikipedia:Dorsum_(anatomy)]
subset: efo_slim
subset: uberon_slim
synonym: "back" EXACT [FMA:14181]
synonym: "back of body proper" EXACT [FMA:14181]
synonym: "dorsal part of organism" EXACT []
xref: BTO:0001713
xref: CALOHA:TS-2223
xref: EFO:0001405
xref: FMA:14181
xref: GAID:30
xref: galen:Back
xref: MESH:D001415
xref: NCIT:C13062
xref: SCTID:123961009
xref: UMLS:C0004600 {source="ncithesaurus:Back"}
xref: Wikipedia:Dorsum_(anatomy)
is_a: UBERON:0000475 ! organism subdivision
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/432px-Gray-back.PNG" xsd:anyURI
property_value: UBPROP:0000007 "dorsal" xsd:string
property_value: UBPROP:0000008 "In humans, called the back, a large posterior area of the human body, rising from the top of the buttocks to the back of the neck and the shoulders. It is the surface opposite to the chest, its height being defined by the vertebral column (commonly referred to as the spine or backbone) and its breadth being supported by the ribcage and shoulders. The spinal canal runs through the spine and provides nerves to the rest of the body" xsd:string

[Term]
id: UBERON:0001138
name: superior mesenteric vein
namespace: uberon
def: "In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine. At its termination behind the neck of the pancreas, the SMV combines with the splenic vein to form the hepatic portal vein. The SMV lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]." [Wikipedia:Superior_mesenteric_vein]
subset: human_reference_atlas
subset: uberon_slim
synonym: "upper mesenteric vein" RELATED [BTO:0002783]
synonym: "vena mesenterica superior" RELATED OMO:0003011 [Wikipedia:Superior_mesenteric_vein]
xref: BTO:0002783
xref: EHDAA2:0001951
xref: EHDAA:5414
xref: EMAPA:18643
xref: FMA:14332
xref: MA:0002179
xref: NCIT:C33687
xref: SCTID:278031001
xref: UMLS:C0226742 {source="ncithesaurus:Superior_Mesenteric_Vein"}
xref: VHOG:0000552
xref: Wikipedia:Superior_mesenteric_vein
is_a: UBERON:0005617 ! mesenteric vein
intersection_of: UBERON:0005617 ! mesenteric vein
intersection_of: drains UBERON:0002108 ! small intestine
relationship: connected_to UBERON:0001639 ! hepatic portal vein
relationship: develops_from UBERON:0005487 {source="Wikipedia:Vitelline_vein"} ! vitelline vein
relationship: drains UBERON:0002108 ! small intestine
relationship: part_of UBERON:0005806 ! portal system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001139
name: common iliac vein
namespace: uberon
def: "A vein that drains the pelvis and lower limbs into the inferior vena cava." [MURDOCH:403, Wikipedia:Common_iliac_vein]
subset: human_reference_atlas
subset: uberon_slim
synonym: "common iliac venous tree" EXACT []
synonym: "vena iliaca communis" RELATED OMO:0003011 [Wikipedia:Common_iliac_vein]
xref: EMAPA:17874
xref: FMA:14333
xref: galen:CommonIliacVein
xref: MA:0002143
xref: NCIT:C32359
xref: SCTID:181398004
xref: UMLS:C0226758 {source="ncithesaurus:Common_Iliac_Vein"}
xref: Wikipedia:Common_iliac_vein
is_a: UBERON:0005610 {source="MA"} ! iliac vein
is_a: UBERON:0015212 ! lateral structure
relationship: in_lateral_side_of UBERON:0001072 {source="FMA-abduced-lr"} ! posterior vena cava
relationship: part_of UBERON:0001072 ! posterior vena cava
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/6/65/Iliac_veins.gif" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "In human anatomy, the common iliac veins are formed by the external iliac veins and internal iliac veins and together, in the abdomen at the level of the fifth lumbar vertebrae, form the inferior vena cava. They drain blood from the pelvis and lower limbs. Both common iliac veins are accompanied along their course by common iliac arteries." xsd:string {source="Wikipedia:Common_iliac_vein"}

[Term]
id: UBERON:0001140
name: renal vein
namespace: uberon
def: "Either of the pair of major vessels which arise from the renal hilus and return blood from the kidneys, suprarenal gland and the ureter to the inferior vena cava." [ISBN:0-683-40008-8, MGI:csmith, MP:0011323]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "kidney vein" EXACT [OBOL:automatic]
synonym: "renal venous tree" EXACT []
synonym: "vein of kidney" EXACT [OBOL:automatic]
synonym: "venae renales" RELATED OMO:0003011 [Wikipedia:Renal_vein]
xref: BTO:0002681
xref: EHDAA2:0001602
xref: EHDAA:8722
xref: EMAPA:28376
xref: FMA:14334
xref: GAID:544
xref: galen:RenalVein
xref: MA:0002210
xref: MESH:D012082
xref: NCIT:C33462
xref: SCTID:116358006
xref: UMLS:C0035092 {source="ncithesaurus:Renal_Vein"}
xref: Wikipedia:Renal_vein
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0002113 ! kidney
relationship: drains UBERON:0002113 ! kidney
relationship: part_of RO:0002577 ! system
relationship: tributary_of UBERON:0001072 ! posterior vena cava
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/76/Gray1122.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The renal veins are veins that drain the kidney. They connect the kidney to the inferior vena cava. It is usually singular to each kidney, except in the condition 'multiple renal veins'. It also divides into 2 divisions upon entering the kidney: the anterior branch which receives blood from the anterior portion of the kidney and, the posterior branch which receives blood from the posterior portion. Often, each renal vein will have a branch that receives blood from the ureter. [WP,unvetted][Wikipedia:Renal_vein]." xsd:string {source="Wikipedia:Renal_vein"}
property_value: UBPROP:0000012 "in EHDAA2, the renal vein is part of the kidney" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0001141
name: right renal vein
namespace: uberon
def: "A renal vein that drains the right kidney." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
xref: EMAPA:37381 {source="MA:th"}
xref: FMA:14335
xref: MA:0002212
xref: NCIT:C52695
xref: SCTID:116357001
xref: UMLS:C0508000 {source="ncithesaurus:Right_Renal_Vein"}
is_a: UBERON:0001140 ! renal vein
intersection_of: UBERON:0001140 ! renal vein
intersection_of: drains UBERON:0004539 ! right kidney
relationship: drains UBERON:0004539 ! right kidney
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A vein that drains blood from the right kidney into the inferior vena cava[ncithesaurus]." xsd:string {source="ncithesaurus:Right_Renal_Vein"}

[Term]
id: UBERON:0001142
name: left renal vein
namespace: uberon
def: "A renal vein that drains the left kidney." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
xref: EMAPA:37166 {source="MA:th"}
xref: FMA:14336
xref: MA:0002211
xref: NCIT:C52693
xref: SCTID:116356005
xref: UMLS:C0508001 {source="ncithesaurus:Left_Renal_Vein"}
is_a: UBERON:0001140 ! renal vein
intersection_of: UBERON:0001140 ! renal vein
intersection_of: drains UBERON:0004538 ! left kidney
relationship: drains UBERON:0004538 ! left kidney
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/76/Gray1122.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A vein that drains blood from the left kidney into the inferior vena cava[ncithesaurus]." xsd:string {source="ncithesaurus:Left_Renal_Vein"}

[Term]
id: UBERON:0001143
name: hepatic vein
namespace: uberon
def: "Vein that carries blood away from the liver[ZFA]." [https://sourceforge.net/tracker/?func=detail&aid=3565355&group_id=76834&atid=1205376, Wikipedia:Hepatic_vein, ZFA:0000670]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "hepatic veins" RELATED OMO:0003004 []
synonym: "liver vein" EXACT [OBOL:automatic]
synonym: "vein of liver" EXACT [OBOL:automatic]
synonym: "vena hepatica" EXACT OMO:0003011 []
synonym: "venae hepaticae" RELATED OMO:0003011 [Wikipedia:Hepatic_vein]
xref: AAO:0010216
xref: EMAPA:19221
xref: FMA:14337
xref: GAID:534
xref: galen:HepaticVein
xref: MA:0003015
xref: MESH:D006503
xref: NCIT:C32736
xref: SCTID:278191001
xref: TAO:0000670
xref: UMLS:C0019155 {source="ncithesaurus:Hepatic_Vein"}
xref: Wikipedia:Hepatic_vein
xref: XAO:0000387
xref: ZFA:0000670
is_a: UBERON:0013126 ! vein of abdomen
is_a: UBERON:0015796 ! liver blood vessel
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0002107 ! liver
disjoint_from: UBERON:0001639 ! hepatic portal vein
relationship: develops_from UBERON:0005487 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="Wikipedia:Vitelline_vein"} ! vitelline vein
relationship: drains UBERON:0002107 ! liver
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0006877 ! vasculature of liver
relationship: tributary_of UBERON:0001072 {source="FMA-abduced-lr"} ! posterior vena cava
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/61/Gray1121.png" xsd:anyURI
property_value: editor_note "todo - add developmental relationships for other taxa" xsd:string

[Term]
id: UBERON:0001144
name: testicular vein
namespace: uberon
def: "A vein that carries deoxygenated blood from a single male gonad. It is the male equivalent of the ovarian vein, and is the venous counterpart of the testicular artery. It is a paired vein, with one supplying each testis." [http://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/?func=detail&aid=3220553&group_id=76834&atid=1205376, Wikipedia:Testicular_vein]
subset: uberon_slim
synonym: "male gonadal vein" EXACT [Wikipedia:Testicular_vein]
synonym: "spermatic vein" EXACT [Wikipedia:Testicular_vein]
synonym: "testicle vein" EXACT [OBOL:automatic]
synonym: "testicular venous tree" EXACT [Wikipedia:Testicular_vein]
synonym: "vein of testicle" EXACT [OBOL:automatic]
synonym: "vena tesicularis" RELATED [BTO:0002678]
synonym: "vena testicularis dextra" RELATED OMO:0003011 [Wikipedia:Testicular_vein]
synonym: "vena testicularis sinistra" RELATED OMO:0003011 [Wikipedia:Testicular_vein]
synonym: "venae spermaticae" RELATED OMO:0003011 [Wikipedia:Testicular_vein]
xref: BTO:0002678
xref: EMAPA:18647
xref: FMA:14344
xref: MA:0002218
xref: MA:0002234
xref: NCIT:C53050
xref: SCTID:264496006
xref: UMLS:C0226718 {source="ncithesaurus:Spermatic_Vein"}
xref: Wikipedia:Testicular_vein
is_a: UBERON:0001638 ! vein
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0000473 ! testis
relationship: connected_to UBERON:0001072 ! posterior vena cava
relationship: connected_to UBERON:0001330 ! pampiniform plexus
relationship: drains UBERON:0000473 ! testis
relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism
relationship: part_of RO:0002577 ! system
relationship: sexually_homologous_to UBERON:0001145 ! ovarian vein
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1b/Gray590.png" xsd:anyURI
property_value: editor_note "TODO - check testicular vs spermatic vein (MA:0002218)" xsd:string
property_value: UBPROP:0000008 "In humans, the right testicular vein generally joins the inferior vena cava; the left testicular vein, unlike the right, often joins the left renal vein instead of the inferior vena cava. The veins emerge from the back of the testis, and receive tributaries from the epididymis; they unite and form a convoluted plexus, called the pampiniform plexus, which constitutes the greater mass of the spermatic cord; the vessels composing this plexus are very numerous, and ascend along the cord, in front of the ductus deferens. Below the subcutaneous inguinal ring, they unite to form three or four veins, which pass along the inguinal canal, and, entering the abdomen through the abdominal inguinal ring, coalesce to form two veins, which ascend on the Psoas major, behind the peritoneum, lying one on either side of the internal spermatic artery. These unite to form a single vein, which opens, on the right side, into the inferior vena cava (at an acute angle), on the left side into the left renal vein (at a right angle). The spermatic veins are provided with valves. The left spermatic vein passes behind the iliac colon and is thus exposed to pressure from the contents of that part of the bowel" xsd:string

[Term]
id: UBERON:0001145
name: ovarian vein
namespace: uberon
def: "A vein that carries deoxygenated blood from its corresponding ovary to inferior vena cava or one of its tributaries." [Wikipedia:Ovarian_vein]
subset: uberon_slim
synonym: "female reproductive system gonad vein" EXACT [OBOL:automatic]
synonym: "female reproductive system gonada vein" EXACT [OBOL:automatic]
synonym: "gonad of female reproductive system vein" EXACT [OBOL:automatic]
synonym: "gonada of female reproductive system vein" EXACT [OBOL:automatic]
synonym: "ovary vein" EXACT [OBOL:automatic]
synonym: "vein of female reproductive system gonad" EXACT [OBOL:automatic]
synonym: "vein of female reproductive system gonada" EXACT [OBOL:automatic]
synonym: "vein of gonad of female reproductive system" EXACT [OBOL:automatic]
synonym: "vein of gonada of female reproductive system" EXACT [OBOL:automatic]
synonym: "vein of ovary" EXACT [OBOL:automatic]
synonym: "vena ovarica dextra" RELATED OMO:0003011 [Wikipedia:Ovarian_vein]
synonym: "vena ovarica sinistra" RELATED OMO:0003011 [Wikipedia:Ovarian_vein]
xref: EMAPA:18644
xref: FMA:14346
xref: MA:0002186
xref: NCIT:C53058
xref: SCTID:278193003
xref: UMLS:C0226720 {source="ncithesaurus:Ovarian_Vein"}
xref: Wikipedia:Ovarian_vein
is_a: UBERON:0001638 ! vein
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0000992 ! ovary
relationship: drains UBERON:0000992 ! ovary
relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/cf/Ovarschaf.jpg" xsd:anyURI

[Term]
id: UBERON:0001152
name: cystic duct
namespace: uberon
def: "The tubular structure that conducts gall bladder contents from the gall bladder to the common bile duct." [ISBN:0-683-40008-8, MP:0009493]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "ductus cysticus" RELATED OMO:0003011 [Wikipedia:Cystic_duct]
xref: EHDAA2:0000333
xref: EHDAA:3045
xref: EMAPA:16841
xref: FMA:14539
xref: GAID:290
xref: galen:CysticDuct
xref: MA:0000355
xref: MESH:D003549
xref: NCIT:C32421
xref: SCTID:245398005
xref: TAO:0005166
xref: UMLS:C0010672 {source="ncithesaurus:Cystic_Duct"}
xref: VHOG:0000213
xref: Wikipedia:Cystic_duct
xref: ZFA:0005166
is_a: UBERON:0003703 {source="FMA"} ! extrahepatic bile duct
intersection_of: UBERON:0000058 ! duct
intersection_of: continuous_with UBERON:0001174 ! common bile duct
intersection_of: continuous_with UBERON:0002110 ! gallbladder
disjoint_from: UBERON:0005171 ! hepatic duct
relationship: channels_into UBERON:0001174 ! common bile duct
relationship: continuous_with UBERON:0001174 ! common bile duct
relationship: continuous_with UBERON:0002110 ! gallbladder
relationship: develops_from UBERON:0005604 {source="EHDAA2"} ! extrahepatic part of hepatic duct
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI
property_value: UBPROP:0000001 "Duct that connects the gall bladder and the common bile duct.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005166", ontology="TAO", source="ZFIN:Curator"}
property_value: UBPROP:0000001 "The duct of the gallbladder which joins the common hepatic duct, thus forming the common biliary duct. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000213", ontology="VHOG", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001155
name: colon
namespace: uberon
def: "A portion of the large intestine before it becomes the rectum. In mammals, the colon is the most part of the large intestine, excluding the vermiform appendix, the rectum and the anal canal." [http://orcid.org/0000-0002-2825-0621, http://orcid.org/0000-0002-6601-2165, Wikipedia:Colon_(anatomy), ZFIN:curator]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "hindgut" RELATED []
synonym: "large bowel" EXACT []
synonym: "posterior intestine" NARROW []
xref: AAO:0010400
xref: BTO:0000269
xref: CALOHA:TS-0158
xref: EFO:0000361
xref: EMAPA:18939
xref: EV:0100079
xref: FMA:14543
xref: GAID:309
xref: galen:Colon
xref: MA:0000335
xref: MAP:0000001
xref: MAT:0000526
xref: MESH:D003106
xref: NCIT:C12382
xref: SCTID:302508007
xref: TAO:0000706
xref: UMLS:C0009368 {source="ncithesaurus:Colon"}
xref: VHOG:0000648
xref: Wikipedia:Colon_(anatomy)
xref: XAO:0000243
xref: ZFA:0000706
is_a: UBERON:0004921 {order="3", source="cjm"} ! subdivision of digestive tract
relationship: contributes_to_morphology_of UBERON:0000059 ! large intestine
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0000059 {source="FMA"} ! large intestine
property_value: editor_note "Some references do not consider the caecum to be part of the colon." xsd:string {xref="http://orcid.org/0000-0002-1572-1316"}
property_value: editor_note "TODO - abstract this such that it legitimately covers all vertebrates" xsd:string
property_value: UBPROP:0000001 "The last portion of the digestive system, it extracts water and salt from solid wastes before they are eliminated from the body.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010400", ontology="AAO", source="UBERON:0001155"}
property_value: UBPROP:0000001 "The posterior intestine has short longitudinally arranged epithelial folds which are similar to the colon of higher vertebrates. Wallace et al, 2005.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000706", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000648", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "colonic" xsd:string
property_value: UBPROP:0000008 "In mammals, the colon consists of four sections: the ascending colon, the transverse colon, the descending colon, and the sigmoid colon[WP]" xsd:string
property_value: UBPROP:0000008 "In zebrafish, the posterior intestine has short longitudinally arranged epithelial folds which are similar to the colon of higher vertebrates[ZFIN]" xsd:string
property_value: UBPROP:0000009 "it extracts water and salt from solid wastes before they are eliminated from the body[WP]" xsd:string

[Term]
id: UBERON:0001159
name: sigmoid colon
namespace: uberon
def: "The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity." [Wikipedia:Sigmoid_colon]
subset: efo_slim
subset: human_reference_atlas
subset: uberon_slim
synonym: "colon sigmoideum" RELATED OMO:0003011 [Wikipedia:Sigmoid_colon]
synonym: "pelvic colon" RELATED []
synonym: "sigmoid colon" RELATED []
synonym: "sigmoid flexure" RELATED []
xref: BTO:0000645
xref: CALOHA:TS-2044
xref: EFO:0000846
xref: EMAPA:36391
xref: FMA:14548
xref: galen:SigmoidColon
xref: MAT:0000314
xref: MESH:D012809
xref: MIAA:0000314
xref: NCIT:C12384
xref: NCIT:C33550
xref: SCTID:362166007
xref: UMLS:C0227391 {source="ncithesaurus:Sigmoid_Colon"}
xref: UMLS:C0682612 {source="ncithesaurus:Sigmoid_Flexure"}
xref: Wikipedia:Sigmoid_colon
is_a: UBERON:0000168 {source="FMA"} ! proximal-distal subdivision of colon
relationship: continuous_with UBERON:0001052 ! rectum
relationship: develops_from UBERON:0001046 {source="Wikipedia"} ! hindgut
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/3b/Dickdarm-Schema.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_F_Intestine_Large.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/SBU_M_Intestine_Large.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001161
name: body of stomach
namespace: uberon
def: "The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]." [GO:0014845, Wikipedia:Body_of_stomach]
subset: uberon_slim
synonym: "corpus gastricum" RELATED OMO:0003011 [BTO:0000505, Wikipedia:Body_of_stomach]
synonym: "corpus gastricum (ventriculare)" EXACT []
synonym: "corpus ventriculare" RELATED [BTO:0000505]
synonym: "corpus ventriculi" RELATED [BTO:0000505]
synonym: "gastric body" EXACT []
synonym: "gastric corpus" RELATED []
synonym: "stomach body" EXACT []
xref: BTO:0000505
xref: EMAPA:35810
xref: FMA:14560
xref: galen:GastricCorpus
xref: MA:0002559
xref: NCIT:C12258
xref: SCTID:362140009
xref: UMLS:C0227230 {source="ncithesaurus:Body_of_Stomach"}
xref: Wikipedia:Body_of_stomach
is_a: UBERON:0009870 {source="FMA"} ! zone of stomach
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg" xsd:anyURI
property_value: editor_note "we include this as zone of stomach even though it is not distinguished by gland type" xsd:string

[Term]
id: UBERON:0001165
name: pyloric antrum
namespace: uberon
def: "The area at the bottom of the stomach on the caudal side of the pyloric canal that contains gastrin-producing G cells, which stimulate acid production, and the luminal pH-sensitive population of somatostatin-producing D cells." [ISBN:0-683-40008-8, MP:0010790]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "antrum" BROAD []
synonym: "antrum of stomach" EXACT []
synonym: "antrum of Willis" RELATED [BTO:0001732]
synonym: "antrum pylori" RELATED [BTO:0001732]
synonym: "antrum pyloricum" RELATED OMO:0003011 [BTO:0001732, Wikipedia:Pyloric_antrum]
synonym: "gastric antrum" RELATED [BTO:0001732]
synonym: "stomach antrum" RELATED []
synonym: "stomach pyloric antrum" EXACT []
xref: BTO:0001732
xref: EFO:0002555
xref: EMAPA:17891
xref: FMA:14579
xref: GAID:332
xref: galen:PyloricAntrum
xref: MA:0001624
xref: MESH:D011706
xref: NCIT:C12259
xref: SCTID:362142001
xref: UMLS:C0034193 {source="ncithesaurus:Antrum_Pylori"}
xref: Wikipedia:Pyloric_antrum
is_a: UBERON:0009870 {source="FMA"} ! zone of stomach
relationship: continuous_with UBERON:0001161 ! body of stomach
relationship: contributes_to_morphology_of UBERON:0001166 ! pylorus
relationship: has_part CL:0000502 ! type D enteroendocrine cell
relationship: has_part CL:0000508 ! type G enteroendocrine cell
relationship: part_of UBERON:0001166 {source="Wikipedia"} ! pylorus
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg" xsd:anyURI

[Term]
id: UBERON:0001166
name: pylorus
namespace: uberon
def: "The stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum." [MGI:csmith, MP:0010785]
subset: pheno_slim
subset: uberon_slim
synonym: "pars pylorica" EXACT OMO:0003011 []
synonym: "pars pylorica gastricae" EXACT OMO:0003011 [FMA:14581, FMA:TA]
synonym: "pyloric part of stomach" EXACT []
synonym: "pyloric region" EXACT []
synonym: "stomach pyloric region" EXACT [EHDAA2:0001580]
synonym: "valvula pylori" RELATED OMO:0003011 [Wikipedia:Pylorus]
xref: BTO:0001146
xref: EHDAA2:0001580
xref: EHDAA:4860
xref: EMAPA:17631
xref: FMA:14581
xref: GAID:333
xref: galen:Pylorus
xref: MA:0002560
xref: MESH:D011708
xref: NCIT:C12260
xref: SCTID:362143006
xref: UMLS:C0034196 {source="ncithesaurus:Pylorus"}
xref: VHOG:0000420
xref: Wikipedia:Pylorus
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0009870 ! zone of stomach
intersection_of: UBERON:0009870 ! zone of stomach
intersection_of: has_part UBERON:0001165 ! pyloric antrum
intersection_of: has_part UBERON:0008858 ! pyloric canal
intersection_of: has_part UBERON:0008861 ! pyloric gastric gland
relationship: contributes_to_morphology_of UBERON:0000945 ! stomach
relationship: has_part UBERON:0001165 ! pyloric antrum
relationship: has_part UBERON:0008858 ! pyloric canal
relationship: has_part UBERON:0008861 ! pyloric gastric gland
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg" xsd:anyURI
property_value: editor_note "We follow Kardong in defining stomach regions by glands" xsd:string
property_value: UBPROP:0000001 "The orifice which allows the passage from the stomach into the intestine. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000420", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000420", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "pyloric" xsd:string

[Term]
id: UBERON:0001167
name: wall of stomach
namespace: uberon
def: "The layered structure that makes up the stomach, typiclly consists of a serous coat, a muscular coat, a mucous membrane, and other tissue layers in between." [MGI:csmith, MP:0010783]
subset: pheno_slim
synonym: "anatomical wall of stomach" EXACT [OBOL:automatic]
synonym: "anatomical wall of ventriculus" EXACT [OBOL:automatic]
synonym: "gastric wall" EXACT []
synonym: "stomach anatomical wall" EXACT [OBOL:automatic]
synonym: "stomach wall" EXACT []
synonym: "ventriculus anatomical wall" EXACT [OBOL:automatic]
synonym: "ventriculus wall" EXACT [OBOL:automatic]
synonym: "wall of ventriculus" EXACT [OBOL:automatic]
xref: EMAPA:35826
xref: FMA:14582
xref: galen:WallOfStomach
xref: MA:0002692
xref: SCTID:279995000
is_a: UBERON:0000328 ! gut wall
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000945 ! stomach
relationship: contributes_to_morphology_of UBERON:0000945 ! stomach
relationship: part_of UBERON:0000945 ! stomach

[Term]
id: UBERON:0001168
name: wall of small intestine
namespace: uberon
def: "An anatomical wall that is part of a small intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "anatomical wall of small bowel" EXACT [OBOL:automatic]
synonym: "anatomical wall of small intestine" EXACT [OBOL:automatic]
synonym: "small bowel anatomical wall" EXACT [OBOL:automatic]
synonym: "small bowel wall" EXACT [OBOL:automatic]
synonym: "small intestinal wall" EXACT []
synonym: "small intestine anatomical wall" EXACT [OBOL:automatic]
synonym: "small intestine wall" EXACT []
synonym: "wall of small bowel" EXACT [OBOL:automatic]
xref: EMAPA:35785
xref: FMA:14615
xref: MA:0002696
xref: NCIT:C33573
xref: UMLS:C1519375 {source="ncithesaurus:Small_Intestinal_Wall_Tissue"}
is_a: UBERON:0001262 ! wall of intestine
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0002108 ! small intestine

[Term]
id: UBERON:0001169
name: wall of large intestine
namespace: uberon
def: "An anatomical wall that is part of a large intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "anatomical wall of large intestine" EXACT [OBOL:automatic]
synonym: "large intestinal wall" EXACT []
synonym: "large intestine anatomical wall" EXACT [OBOL:automatic]
synonym: "large intestine wall" EXACT []
xref: EMAPA:35470
xref: FMA:14619
xref: MA:0002695
is_a: UBERON:0001262 ! wall of intestine
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000059 ! large intestine
relationship: part_of UBERON:0000059 ! large intestine

[Term]
id: UBERON:0001170
name: mesentery of small intestine
namespace: uberon
def: "The peritoneum responsible for connecting the jejunum and ileum (parts of the small intestine) to the back wall of the abdomen. Between the two sheets of peritoneum are blood vessels, lymph vessels, and nerves. This allows these parts of the small intestine to move relatively freely within the abdominopelvic cavity. The brain, however, cannot map sensation accurately, so sensation is usually referred to the midline, an example of referred pain[WP]." [Wikipedia:Mesentery#Mesentery_.28proper.29]
synonym: "mesentery (proper)" EXACT [Wikipedia:Mesentery]
synonym: "mesentery proper" EXACT [FMA:14643]
synonym: "small intestinal mesentery" EXACT [FMA:14643]
synonym: "small intestine mesentery" EXACT [OBOL:automatic]
xref: EMAPA:37745 {source="MA:th"}
xref: FMA:14643
xref: MA:0001555
xref: SCTID:245456008
xref: Wikipedia:Mesentery#Mesentery_.28proper.29
is_a: UBERON:0001206 ! serosa of small intestine
is_a: UBERON:0004854 ! gastrointestinal system mesentery
is_a: UBERON:0007826 {source="FMA"} ! peritoneal mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0002108 ! small intestine

[Term]
id: UBERON:0001171
name: portal lobule
namespace: uberon
def: "The triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel." [MP:0008992]
subset: pheno_slim
xref: FMA:14653
xref: MA:0002498
xref: NCIT:C33341
xref: UMLS:C0682620 {source="ncithesaurus:Portal_Lobule"}
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0009911 {source="FMA"} ! lobule
relationship: contributes_to_morphology_of UBERON:0001280 ! liver parenchyma
relationship: part_of UBERON:0001280 {source="MA", source="MP"} ! liver parenchyma

[Term]
id: UBERON:0001172
name: hepatic acinus
namespace: uberon
def: "The functional unit of the liver, consisting of a mass of hepatocytes from adjacent liver lobules aligned around the hepatic arterioles and portal venules just as they anastomose into sinusoids." [http://orcid.org/0000-0002-6601-2165, http://www.vivo.colostate.edu/hbooks/pathphys/digestion/liver/histo_acinus.html]
synonym: "liver acinus" EXACT []
synonym: "portal acinus" EXACT []
xref: EMAPA:35497
xref: FMA:14654
xref: MA:0002496
xref: NCIT:C32992
xref: SCTID:272214009
xref: UMLS:C0227519 {source="ncithesaurus:Liver_Acinus"}
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0011858 ! acinus of exocrine gland
relationship: overlaps UBERON:0001171 ! portal lobule
relationship: overlaps UBERON:0004647 ! liver lobule
relationship: part_of UBERON:0001280 {source="cjm"} ! liver parenchyma

[Term]
id: UBERON:0001173
name: biliary tree
namespace: uberon
def: "A complex network of conduits that begins with the canals of Hering (intralobar bile duct) and progressively merges into a system of interlobular, septal, and major ducts which then coalesce to form the extrahepatic bile ducts, which finally deliver bile to the intestine, and in some species to the gallbladder." [DOI:10.1002/ar.20664]
comment: The path in many species is as follows: Bile canaliculi -> Canals of Hering (intralobar bile duct) -> interlobular bile ducts -> intrahepatic bile ducts -> left and right hepatic ducts merge to form -> common hepatic duct *exits liver* and joins -> cystic duct (from gall bladder) forming -> common bile duct -> joins with pancreatic duct -> forming ampulla of Vater -> enters duodenum [WP]
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "biliary tract" RELATED [MA:0001273]
xref: AAO:0011020
xref: EMAPA:35172
xref: FMA:14665
xref: MESH:D001659 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: SCTID:181267003
xref: UMLS:C0005423 {source="ncithesaurus:Biliary_Tract"}
xref: Wikipedia:Biliary_tract
xref: XAO:0000455
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0013765 ! digestive system element
intersection_of: UBERON:0000062 ! organ
intersection_of: composed_primarily_of UBERON:0002394 ! bile duct
intersection_of: part_of UBERON:0002294 ! biliary system
relationship: composed_primarily_of UBERON:0002394 ! bile duct
relationship: contributes_to_morphology_of UBERON:0002423 ! hepatobiliary system
relationship: develops_from UBERON:0004912 ! biliary bud
relationship: has_part UBERON:0001246 ! interlobular bile duct
relationship: has_part UBERON:0001282 ! intralobular bile duct
relationship: has_part UBERON:0003703 ! extrahepatic bile duct
relationship: part_of UBERON:0002294 ! biliary system
property_value: RO:0002171 UBERON:0002110
property_value: UBPROP:0000001 "Hollow tree organ, the organ parts of which consist of the bile ducts.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011020", ontology="AAO", source="UBERON:0001173"}

[Term]
id: UBERON:0001174
name: common bile duct
namespace: uberon
def: "The part of the biliary tree formed by the union of the cystic duct and the common hepatic duct." [MGI:csmith, MP:0009495]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "ductus choledochus" RELATED OMO:0003011 [Wikipedia:Common_bile_duct]
synonym: "ductus choledochus (biliaris)" EXACT []
xref: EHDAA2:0000303
xref: EHDAA:3981
xref: EMAPA:17201
xref: FMA:14667
xref: GAID:282
xref: galen:CommonBileDuct
xref: MA:0001631
xref: MESH:D003135
xref: NCIT:C12698
xref: SCTID:362199009
xref: TAO:0005165
xref: UMLS:C0009437 {source="ncithesaurus:Common_Bile_Duct"}
xref: VHOG:0000214
xref: Wikipedia:Common_bile_duct
xref: ZFA:0005165
is_a: UBERON:0003703 ! extrahepatic bile duct
relationship: channels_into UBERON:0001064 ! ventral pancreatic duct
relationship: continuous_with UBERON:0001152 ! cystic duct
relationship: continuous_with UBERON:0001175 ! common hepatic duct
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Digestive system duct that collects bile from the hepatic bile duct and the cystic duct.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005165", ontology="TAO", source="ZFIN:Curator"}
property_value: UBPROP:0000001 "The duct formed by the union of the common hepatic and cystic ducts. [Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, adapted_from_Dorian_AF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000214", ontology="VHOG", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001175
name: common hepatic duct
namespace: uberon
def: "Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct[GAID]. The common hepatic duct is the duct formed by the convergence of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct[WP]." [Wikipedia:Common_hepatic_duct, ZFIN:curator]
subset: pheno_slim
subset: uberon_slim
synonym: "ductus hepaticus communis" RELATED OMO:0003011 [Wikipedia:Common_hepatic_duct]
synonym: "hepatic duct" RELATED []
xref: EMAPA:19101
xref: FMA:14668
xref: GAID:286
xref: MA:0002660
xref: MESH:D006500
xref: NCIT:C32356
xref: SCTID:245403006
xref: UMLS:C0019149 {source="ncithesaurus:Common_Hepatic_Duct"}
xref: VHOG:0000220
xref: Wikipedia:Common_hepatic_duct
is_a: UBERON:0003703 {source="FMA"} ! extrahepatic bile duct
relationship: channels_into UBERON:0001174 ! common bile duct
relationship: continuous_with UBERON:0001176 {source="Wikipedia"} ! right hepatic duct
relationship: continuous_with UBERON:0001177 {source="Wikipedia"} ! left hepatic duct
relationship: develops_from UBERON:0010081 ! future common hepatic duct
relationship: immediate_transformation_of UBERON:0010081 {evidence="definitional"} ! future common hepatic duct
relationship: part_of UBERON:0005604 {source="MA"} ! extrahepatic part of hepatic duct
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg" xsd:anyURI
property_value: editor_note "TODO - MA distinguishes between bile duct, hepatic duct, common bile duct and common hepatic duct. in FMA hepatic duct and common hepatic duct are the same. Common is part of extra-hepatic part" xsd:string
property_value: UBPROP:0000001 "The duct which conveys the bile from the liver and unites with the cystic duct to form the common bile duct. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000220", ontology="VHOG", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001176
name: right hepatic duct
namespace: uberon
def: "The duct that drains bile from the right half of the liver and joins the left hepatic duct to form the common hepatic duct." [http://www.medterms.com/script/main/art.asp?articlekey=26034]
synonym: "ductus hepaticus dexter" RELATED OMO:0003011 []
xref: EHDAA2:0001727
xref: EHDAA:3992
xref: EMAPA:32797
xref: FMA:14669
xref: MA:0001639
xref: NCIT:C33476
xref: SCTID:245401008
xref: UMLS:C0227557 {source="ncithesaurus:Right_Hepatic_Duct"}
xref: VHOG:0000217
is_a: UBERON:0003703 ! extrahepatic bile duct
intersection_of: UBERON:0003703 ! extrahepatic bile duct
intersection_of: continuous_with UBERON:0001114 ! right lobe of liver
relationship: continuous_with UBERON:0001114 ! right lobe of liver
relationship: part_of UBERON:0005171 ! hepatic duct
property_value: UBPROP:0000001 "The duct which drains bile from the right half of the liver and unites with the left hepatic duct to form the common hepatic duct. [adapted_from_http://www.medterms.com/script/main/art.asp?articlekey=26032][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000217", ontology="VHOG", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001177
name: left hepatic duct
namespace: uberon
def: "The duct that drains bile from the left half of the liver and joins the right hepatic duct to form the common hepatic duct." [http://www.medterms.com/script/main/art.asp?articlekey=26035]
synonym: "ductus hepaticus sinister" RELATED OMO:0003011 []
xref: EHDAA2:0000941
xref: EHDAA:3990
xref: EMAPA:32795
xref: FMA:14670
xref: MA:0001638
xref: NCIT:C32960
xref: SCTID:245400009
xref: UMLS:C0227560 {source="ncithesaurus:Left_Hepatic_Duct"}
xref: VHOG:0000218
is_a: UBERON:0003703 ! extrahepatic bile duct
intersection_of: UBERON:0003703 ! extrahepatic bile duct
intersection_of: continuous_with UBERON:0001115 ! left lobe of liver
relationship: continuous_with UBERON:0001115 ! left lobe of liver
relationship: part_of UBERON:0005171 ! hepatic duct
property_value: UBPROP:0000001 "The duct which drains bile from the left half of the liver and unites with the right hepatic duct to form the common hepatic duct. [adapted_from_http://www.medterms.com/script/main/art.asp?articlekey=26032][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000218", ontology="VHOG", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001178
name: visceral peritoneum
namespace: uberon
def: "The inner layer of peritoneum that is wrapped around organs located inside the intraperitoneal space." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Peritoneum#Types]
subset: uberon_slim
subset: vertebrate_core
synonym: "visceral serous membrane of peritoneum" EXACT [UBERON:cjm]
xref: EMAPA:16592
xref: FMA:14703
xref: SCTID:362702003
xref: TAO:0005132
xref: VHOG:0001528
xref: Wikipedia:Visceral_peritoneum
xref: ZFA:0005132
is_a: UBERON:0022350 ! visceral serous membrane
intersection_of: UBERON:0022350 ! visceral serous membrane
intersection_of: part_of UBERON:0002358 ! peritoneum
relationship: part_of UBERON:0002358 ! peritoneum
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png" xsd:anyURI

[Term]
id: UBERON:0001179
name: peritoneal cavity
namespace: uberon
def: "Anatomical cavity bounded by visceral and parietal peritoneum." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/86, Wikipedia:Peritoneal_cavity]
subset: pheno_slim
subset: uberon_slim
synonym: "cavitas peritonealis" RELATED OMO:0003011 [BTO:0001782, Wikipedia:Peritoneal_cavity]
synonym: "saccus serosus peritonei" RELATED OMO:0003011 [Wikipedia:Peritoneal_cavity]
xref: BTO:0001782
xref: EHDAA2:0001446
xref: EMAPA:16138
xref: FMA:14704
xref: GAID:24
xref: MA:0000054
xref: MESH:D010529
xref: NCIT:C12769
xref: SCTID:181616008
xref: UMLS:C1704247 {source="ncithesaurus:Peritoneal_Cavity"}
xref: VHOG:0000852
xref: Wikipedia:Peritoneal_cavity
is_a: UBERON:0035809 ! serous cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: adjacent_to UBERON:0001178 ! visceral peritoneum
intersection_of: adjacent_to UBERON:0001366 ! parietal peritoneum
intersection_of: luminal_space_of UBERON:0035820 ! peritoneal sac
relationship: adjacent_to UBERON:0001178 ! visceral peritoneum
relationship: adjacent_to UBERON:0001366 ! parietal peritoneum
relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom
relationship: luminal_space_of UBERON:0035820 ! peritoneal sac
relationship: part_of UBERON:0035820 ! peritoneal sac
property_value: UBPROP:0000001 "The potential space between the parietal and visceral layers of the peritoneum, which are normally in contact. The peritoneal cavity is divided into the greater and lesser sac. The greater sac is the peritoneal cavity, and the lesser sac is the omental bursa. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000852", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/peritoneal+cavity"}
property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart [of other tetrapods] is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes) Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000852", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001184
name: renal artery
namespace: uberon
def: "One of two laterally paired arteries that supplies the kidneys. These are large arteries that branch from the dorsal aorta in primitive vertebrates." [ISBN:0073040584, Wikipedia:Renal_artery]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "arteria renalis" RELATED OMO:0003011 [Wikipedia:Renal_artery]
synonym: "renal arterial tree" EXACT []
synonym: "renal arteries" RELATED OMO:0003004 []
xref: AAO:0010223
xref: BTO:0001165
xref: EFO:0002552
xref: EHDAA2:0004100
xref: EHDAA:5321
xref: EHDAA:8594
xref: EMAPA:28373
xref: FMA:14751
xref: GAID:507
xref: galen:RenalArtery
xref: MA:0002035
xref: MESH:D012077
xref: NCIT:C12778
xref: RETIRED_EHDAA2:0001600
xref: SCTID:181339005
xref: TAO:0000420
xref: UMLS:C0035065 {source="ncithesaurus:Renal_Artery"}
xref: Wikipedia:Renal_artery
xref: ZFA:0000420
is_a: UBERON:0012254 ! abdominal aorta artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0002113 ! kidney
relationship: supplies UBERON:0002113 ! kidney
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: editor_note "renal arteries vary widely even in humans. Sub-structures should be checked for taxon variability." xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Artery which supplies blood via branches to the gonads, oviducts, and kidneys.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010223", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The renal arteries normally arise off the side of the abdominal aorta, immediately below the superior mesenteric artery, and supply the kidneys with blood. Each is directed across the crus of the diaphragm, so as to form nearly a right angle with the aorta. The renal arteries carry a large portion of total blood flow to the kidneys. Up to a third of total cardiac output can pass through the renal arteries to be filtered by the kidneys. The arterial supply of the kidneys is variable and there may be one or more renal arteries supplying each kidney. It is located above the renal vein. It has a radius of approximately 0.25cm, 0.26 cm at the root. The measured mean diameter can differ depending on the imaging method used. For example, the diameter was found to be 5.04 ± 0.74 mm using ultrasound, but 5.68 ± 1.19 mm using angiography. [WP,unvetted].[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Renal_artery"}

[Term]
id: UBERON:0001185
name: right renal artery
namespace: uberon
def: "Renal artery that supplies the right kidney." [https://orcid.org/0000-0002-6601-2165]
comment: The right [renal artery] passes behind the inferior vena cava, the right renal vein, the head of the pancreas, and the descending part of the duodenum[WP]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "right renal arterial tree" EXACT []
xref: EMAPA:37380 {source="MA:th"}
xref: FMA:14752
xref: MA:0002037
xref: NCIT:C52740
xref: SCTID:36800007
xref: UMLS:C0226332 {source="ncithesaurus:Right_Renal_Artery"}
is_a: UBERON:0001184 ! renal artery
intersection_of: UBERON:0001184 ! renal artery
intersection_of: supplies UBERON:0004539 ! right kidney
relationship: supplies UBERON:0004539 ! right kidney
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001186
name: left renal artery
namespace: uberon
def: "Renal artery that supplies the left kidney." [https://orcid.org/0000-0002-6601-2165]
comment: The left [renal artery] is somewhat higher than the right; it lies behind the left renal vein, the body of the pancreas and the splenic vein, and is crossed by the inferior mesenteric vein[WP]
subset: human_reference_atlas
subset: pheno_slim
synonym: "left renal arterial tree" EXACT []
xref: EMAPA:37098 {source="MA:th"}
xref: FMA:14753
xref: MA:0002036
xref: NCIT:C52741
xref: SCTID:19215005
xref: UMLS:C0226333 {source="ncithesaurus:Left_Renal_Artery"}
is_a: UBERON:0001184 ! renal artery
intersection_of: UBERON:0001184 ! renal artery
intersection_of: supplies UBERON:0004538 ! left kidney
relationship: supplies UBERON:0004538 ! left kidney
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001187
name: testicular artery
namespace: uberon
def: "One of a pair of arteries that is a branch of the abdominal aorta that supplies blood to a male gonad." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Testicular_artery]
subset: human_reference_atlas
subset: uberon_slim
synonym: "arteria testicularis" RELATED OMO:0003011 [Wikipedia:Testicular_artery]
synonym: "internal spermatic" RELATED [Wikipedia:Testicular_artery]
synonym: "internal spermatic arteries" RELATED [Wikipedia:Testicular_artery]
synonym: "internal spermatic artery" RELATED [Wikipedia:Testicular_artery]
synonym: "internal spermatic vessels" RELATED [Wikipedia:Testicular_artery]
synonym: "spermatic arteries" RELATED [Wikipedia:Testicular_artery]
synonym: "spermatic artery" RELATED [Wikipedia:Testicular_artery]
synonym: "spermatic vessels" RELATED [Wikipedia:Testicular_artery]
synonym: "testicular arterial tree" EXACT []
synonym: "testicular arteries" RELATED [Wikipedia:Testicular_artery]
xref: EMAPA:18621
xref: FMA:14758
xref: MA:0002063
xref: SCTID:244281003
xref: Wikipedia:Testicular_artery
is_a: UBERON:0010192 ! genital artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0000473 ! testis
relationship: supplies UBERON:0000473 ! testis
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001188
name: right testicular artery
namespace: uberon
def: "A testicular artery that supplies a right testicle." [OBOL:automatic]
subset: human_reference_atlas
synonym: "right spermatic artery" EXACT []
synonym: "trunk of right testicular arterial tree" EXACT []
xref: EMAPA:37382 {source="MA:th"}
xref: FMA:14759
xref: MA:0002042
xref: NCIT:C52738
xref: UMLS:C0734076 {source="ncithesaurus:Right_Spermatic_Artery"}
is_a: UBERON:0001187 ! testicular artery
is_a: UBERON:0003468 ! ureteric segment of renal artery
intersection_of: UBERON:0001187 ! testicular artery
intersection_of: supplies UBERON:0004534 ! right testis
relationship: supplies UBERON:0001222 ! right ureter
relationship: supplies UBERON:0004534 ! right testis
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001189
name: left testicular artery
namespace: uberon
def: "A testicular artery that supplies a left testicle." [OBOL:automatic]
subset: human_reference_atlas
synonym: "left spermatic artery" EXACT []
synonym: "trunk of left testicular arterial tree" EXACT []
xref: EMAPA:37099 {source="MA:th"}
xref: FMA:14760
xref: MA:0002041
xref: NCIT:C52739
xref: UMLS:C0734077 {source="ncithesaurus:Left_Spermatic_Artery"}
is_a: UBERON:0001187 ! testicular artery
is_a: UBERON:0003468 ! ureteric segment of renal artery
intersection_of: UBERON:0001187 ! testicular artery
intersection_of: supplies UBERON:0004533 ! left testis
relationship: supplies UBERON:0001223 ! left ureter
relationship: supplies UBERON:0004533 ! left testis
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001190
name: ovarian artery
namespace: uberon
def: "An artery that supplies an ovary." [OBOL:automatic]
subset: human_reference_atlas
subset: uberon_slim
synonym: "arteria ovarica" RELATED OMO:0003011 [Wikipedia:Ovarian_artery]
synonym: "ovarian arterial tree" EXACT []
xref: EMAPA:18620
xref: FMA:14761
xref: MA:0002012
xref: NCIT:C33242
xref: SCTID:244280002
xref: UMLS:C0226411 {source="ncithesaurus:Ovarian_Artery"}
xref: Wikipedia:Ovarian_artery
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0000992 ! ovary
relationship: connected_to UBERON:0001516 ! abdominal aorta
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0000992 ! ovary
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/ae/Gray1170.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "In human anatomy, the ovarian artery is a blood vessel that supplies oxygenated blood to the ovary. It arises from the abdominal aorta below the renal artery, and does not pass out of the abdomiproperty_value external_definitioncavity. It can be found in the suspensory ligament of the ovary. [WP]." xsd:string {source="Wikipedia:Ovarian_artery"}

[Term]
id: UBERON:0001193
name: hepatic artery
namespace: uberon
def: "An artery that supplies the liver." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Hepatic_artery_proper]
subset: human_reference_atlas
subset: uberon_slim
subset: vertebrate_core
synonym: "arteria hepatica" RELATED [BTO:0004307]
synonym: "arteria hepatica propria" EXACT OMO:0003011 []
xref: BTO:0004307
xref: EMAPA:17859
xref: FMA:14769
xref: GAID:496
xref: galen:HepaticArtery
xref: MA:0001963
xref: MESH:D006499
xref: NCIT:C32729
xref: SCTID:76015000
xref: TAO:0005161
xref: UMLS:C0019145 {source="ncithesaurus:Hepatic_Artery"}
xref: ZFA:0005161
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0002107 ! liver
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0002107 ! liver
property_value: curator_notes "currently defined in a generic fashion." xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4c/Common_and_proper_hepatic_artery.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Artery that supplies blood to the liver.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005161", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0001194
name: splenic artery
namespace: uberon
def: "An artery that supplies the spleen." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: uberon_slim
synonym: "arteria lienalis" RELATED OMO:0003011 [Wikipedia:Splenic_artery]
synonym: "arteria splenica" EXACT OMO:0003011 [Wikipedia:Splenic_artery]
synonym: "lienal artery" EXACT [MA:0001991]
xref: EMAPA:19216
xref: FMA:14773
xref: GAID:510
xref: galen:SplenicArtery
xref: MA:0001991
xref: MA:0003177
xref: MESH:D013157
xref: NCIT:C33597
xref: SCTID:244266009
xref: UMLS:C0037996 {source="ncithesaurus:Splenic_Artery"}
xref: Wikipedia:Splenic_artery
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0002106 ! spleen
disjoint_from: UBERON:0001640 ! celiac artery
relationship: connecting_branch_of UBERON:0001640 ! celiac artery
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0002106 ! spleen
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/a2/Gray1188.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/268" xsd:anyURI

[Term]
id: UBERON:0001199
name: mucosa of stomach
namespace: uberon
def: "The mucosal layer that lines the stomach." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: uberon_slim
synonym: "gastric mucosa" EXACT []
synonym: "gastric mucous membrane" EXACT []
synonym: "Magenschleimhaut" RELATED [BTO:0001308]
synonym: "mucosa of organ of stomach" EXACT [OBOL:automatic]
synonym: "mucosa of organ of ventriculus" EXACT [OBOL:automatic]
synonym: "mucosa of ventriculus" EXACT [OBOL:automatic]
synonym: "mucous membrane of stomach" EXACT []
synonym: "mucous membrane of ventriculus" EXACT [OBOL:automatic]
synonym: "organ mucosa of stomach" EXACT [OBOL:automatic]
synonym: "organ mucosa of ventriculus" EXACT [OBOL:automatic]
synonym: "stomach mucosa" EXACT []
synonym: "stomach mucosa of organ" EXACT [OBOL:automatic]
synonym: "stomach mucous membrane" EXACT [OBOL:automatic]
synonym: "stomach organ mucosa" EXACT [OBOL:automatic]
synonym: "tunica mucosa (gaster)" EXACT []
synonym: "tunica mucosa gastricae" EXACT OMO:0003011 [FMA:14907, FMA:TA]
synonym: "tunica mucosa gastris" RELATED OMO:0003011 [BTO:0001308, Wikipedia:Gastric_mucosa]
synonym: "ventriculus mucosa" EXACT [OBOL:automatic]
synonym: "ventriculus mucosa of organ" EXACT [OBOL:automatic]
synonym: "ventriculus mucous membrane" EXACT [OBOL:automatic]
synonym: "ventriculus organ mucosa" EXACT [OBOL:automatic]
xref: BTO:0001308
xref: CALOHA:TS-0404
xref: EMAPA:35817
xref: FMA:14907
xref: GAID:321
xref: galen:GastricMucosa
xref: MA:0002683
xref: MESH:D005753
xref: NCIT:C32656
xref: SCTID:362131005
xref: UMLS:C0017136 {source="ncithesaurus:Gastric_Mucosa"}
xref: Wikipedia:Gastric_mucosa
is_a: UBERON:0004786 ! gastrointestinal system mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000945 ! stomach
relationship: capable_of GO:0001696 ! gastric acid secretion
relationship: contributes_to_morphology_of UBERON:0001167 ! wall of stomach
relationship: part_of UBERON:0001167 ! wall of stomach
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/1/1c/Normal_gastric_mucosa_intermed_mag.jpg" xsd:anyURI
property_value: UBPROP:0000001 "The gastric mucosa is the mucous membrane layer of the stomach which contains the glands and the gastric pits. In men it is about 1 mm thick and its surface is smooth, soft, and velvety. It consists of epithelium, lamina propria, and the muscularis mucosae. In its fresh state, it is of a pinkish tinge at the pyloric end and of a red or reddish-brown color over the rest of its surface. In infancy it is of a brighter hue, the vascular redness being more marked. It is thin at the cardiac extremity, but thicker toward the pylorus. During the contracted state of the organ it is thrown into numerous plaits or rugae, which, for the most part, have a longitudinal direction, and are most marked toward the pyloric end of the stomach, and along the greater curvature. These folds are entirely obliterated when the organ becomes distended. When examined with a lens, the inner surface of the mucous membrane presents a peculiar honeycomb appearance from being covered with funnel-like depressions or foveolae of a polygonal or hexagonal form, which vary from 0.12 to 0.25 mm. in diameter. These are the ducts of the gastric glands, and at the bottom of each may be seen one or more minute orifices, the openings of the gland tubes. Gastric glands are simple or branched tubular glands that emerge on the deeper part of the gastric foveola, inside the gastric areas and outlined by the folds of the mucosa. There are three types of glands: cardiac glands (in the proximal part of the stomach), oxyntic glands (the dominating type of gland), and pyloric glands. The cardiac glands mainly contain mucus producing cells. The bottom part of the oxyntic glands is dominated by zymogen (chief) cells that produce pepsinogen (an inactive precursor of the pepsin enzyme). Parietal cells, which secrete hydrochloric acid are scattered in the glands, with most of them in the middle part. The upper part of the glands consist of mucous neck cells; in this part the dividing cells are seen. The pyloric glands contain mucus-secreting cells. Several types of endocrine cells are found in all regions of the gastric mucosa. In the pyloric glands contain gastrin producing cells (G cells); this hormone stimulates acid production from the parietal cells. ECL (enterochromaffine-like) cells, found in the oxyntic glands release histamine, which also is a powerful stimulant of the acid secretion. The A cells produce glucagon, which mobilizes the hepatic glycogen, and the enterochromaffin cells that produce serotonin, which stimulates the contraction of the smooth muscles. The surface of the mucous membrane is covered by a single layer of columnar epithelium . This epithelium commences very abruptly at the cardiac orifice, where there is a sudden transition from the stratified epithelium of the esophagus. The epithelial lining of the gland ducts is of the same character and is continuous with the general lining of the stomach. [WP,unvetted][Wikipedia:Gastric_mucosa]." xsd:string {source="Wikipedia:Gastric_mucosa"}

[Term]
id: UBERON:0001200
name: submucosa of stomach
namespace: uberon
def: "The fibrous connective tissue layer beneath the stomach mucosa." [MGI:csmith, MP:0010794]
subset: pheno_slim
synonym: "gastric submucosa" EXACT []
synonym: "stomach submucosa" EXACT []
synonym: "submucosa of ventriculus" EXACT [OBOL:automatic]
synonym: "submucous layer of stomach" RELATED [BTO:0002110]
synonym: "tela submucosa (gaster)" EXACT []
synonym: "tela submucosa gastricae" EXACT OMO:0003011 [FMA:14908, FMA:TA]
synonym: "tela submucosa ventriculi" RELATED [BTO:0002110]
synonym: "ventriculus submucosa" EXACT [OBOL:automatic]
xref: BTO:0002110
xref: EMAPA:35825
xref: FMA:14908
xref: MA:0002685
xref: NCIT:C32663
xref: SCTID:52459002
xref: UMLS:C0227211 {source="ncithesaurus:Gastric_Submucosa"}
is_a: UBERON:0018257 ! submucosa of digestive tract
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0000945 ! stomach
relationship: contributes_to_morphology_of UBERON:0001167 ! wall of stomach
relationship: part_of UBERON:0001167 ! wall of stomach

[Term]
id: UBERON:0001201
name: serosa of stomach
namespace: uberon
def: "The outermost layer of the stomach wall, consisting of layers of connective tissue continuous with the peritoneum." [MGI:csmith, MP:0010793]
subset: pheno_slim
synonym: "anatomical wall of stomach serosa" EXACT [OBOL:automatic]
synonym: "anatomical wall of stomach serous membrane" EXACT [OBOL:automatic]
synonym: "anatomical wall of ventriculus serosa" EXACT [OBOL:automatic]
synonym: "anatomical wall of ventriculus serous membrane" EXACT [OBOL:automatic]
synonym: "gastric serosa" RELATED []
synonym: "gastric wall serosa" EXACT [OBOL:automatic]
synonym: "gastric wall serous membrane" EXACT [OBOL:automatic]
synonym: "serosa of anatomical wall of stomach" EXACT [OBOL:automatic]
synonym: "serosa of anatomical wall of ventriculus" EXACT [OBOL:automatic]
synonym: "serosa of gastric wall" EXACT [OBOL:automatic]
synonym: "serosa of stomach anatomical wall" EXACT [OBOL:automatic]
synonym: "serosa of stomach wall" EXACT [OBOL:automatic]
synonym: "serosa of ventriculus anatomical wall" EXACT [OBOL:automatic]
synonym: "serosa of ventriculus wall" EXACT [OBOL:automatic]
synonym: "serosa of wall of stomach" EXACT [OBOL:automatic]
synonym: "serosa of wall of ventriculus" EXACT [OBOL:automatic]
synonym: "serous coat of stomach" EXACT []
synonym: "serous membrane of anatomical wall of stomach" EXACT [OBOL:automatic]
synonym: "serous membrane of anatomical wall of ventriculus" EXACT [OBOL:automatic]
synonym: "serous membrane of gastric wall" EXACT [OBOL:automatic]
synonym: "serous membrane of stomach anatomical wall" EXACT [OBOL:automatic]
synonym: "serous membrane of stomach wall" EXACT [OBOL:automatic]
synonym: "serous membrane of ventriculus anatomical wall" EXACT [OBOL:automatic]
synonym: "serous membrane of ventriculus wall" EXACT [OBOL:automatic]
synonym: "serous membrane of wall of stomach" EXACT [OBOL:automatic]
synonym: "serous membrane of wall of ventriculus" EXACT [OBOL:automatic]
synonym: "stomach anatomical wall serosa" EXACT [OBOL:automatic]
synonym: "stomach anatomical wall serous membrane" EXACT [OBOL:automatic]
synonym: "stomach serosa" EXACT []
synonym: "stomach wall serosa" EXACT [OBOL:automatic]
synonym: "stomach wall serous membrane" EXACT [OBOL:automatic]
synonym: "tunica serosa (gaster)" EXACT []
synonym: "tunica serosa gastricae" EXACT OMO:0003011 [FMA:14914, FMA:TA]
synonym: "ventriculus anatomical wall serosa" EXACT [OBOL:automatic]
synonym: "ventriculus anatomical wall serous membrane" EXACT [OBOL:automatic]
synonym: "ventriculus wall serosa" EXACT [OBOL:automatic]
synonym: "ventriculus wall serous membrane" EXACT [OBOL:automatic]
synonym: "visceral peritoneum of stomach" EXACT []
synonym: "wall of stomach serosa" EXACT [OBOL:automatic]
synonym: "wall of stomach serous membrane" EXACT [OBOL:automatic]
synonym: "wall of ventriculus serosa" EXACT [OBOL:automatic]
synonym: "wall of ventriculus serous membrane" EXACT [OBOL:automatic]
xref: EMAPA:35822
xref: FMA:14914
xref: MA:0001626
xref: NCIT:C32662
xref: SCTID:1353004
xref: UMLS:C1517453 {source="ncithesaurus:Gastric_Serosal_Surface"}
is_a: UBERON:0004782 ! gastrointestinal system serosa
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0001167 ! wall of stomach
relationship: contributes_to_morphology_of UBERON:0001167 ! wall of stomach
relationship: part_of UBERON:0001167 ! wall of stomach
property_value: editor_note "TODO - check serosa/peritoneum" xsd:string

[Term]
id: UBERON:0001202
name: pyloric sphincter
namespace: uberon
def: "A strong ring of smooth muscle at the end of the pyloric canal which lets food pass from the stomach to the duodenum. It receives sympathetic innervation from the celiac ganglion[WP]." [https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: uberon_slim
synonym: "pyloric valve" EXACT [Wikipedia:Pylorus]
xref: AAO:0011093
xref: EMAPA:19251
xref: FMA:14916
xref: MA:0002952
xref: NCIT:C33433
xref: SCTID:268073008
xref: UMLS:C0227238 {source="ncithesaurus:Pyloric_Sphincter"}
xref: VHOG:0001466
xref: XAO:0000457
is_a: UBERON:0011185 ! gastrointestinal sphincter
intersection_of: UBERON:0004590 ! sphincter muscle
intersection_of: part_of UBERON:0001166 ! pylorus
relationship: adjacent_to UBERON:0002114 ! duodenum
relationship: continuous_with UBERON:0008858 ! pyloric canal
relationship: contributes_to_morphology_of UBERON:0001166 ! pylorus
relationship: part_of UBERON:0001166 ! pylorus
property_value: RO:0002161 NCBITaxon:8355
property_value: UBPROP:0000003 "(...) the adult Xenopus stomach exhibits both glandular and aglandular regions and a distinct pyloric sphincter similar to that of the amniotic vertebrates (...).[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001466", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00076.x", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001204
name: mucosa of small intestine
namespace: uberon
def: "A mucosa that is part of a small intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of organ of small bowel" EXACT [OBOL:automatic]
synonym: "mucosa of organ of small intestine" EXACT [OBOL:automatic]
synonym: "mucosa of small bowel" EXACT [OBOL:automatic]
synonym: "mucous membrane of small bowel" EXACT [OBOL:automatic]
synonym: "mucous membrane of small intestine" EXACT []
synonym: "organ mucosa of small bowel" EXACT [OBOL:automatic]
synonym: "organ mucosa of small intestine" EXACT [OBOL:automatic]
synonym: "small bowel mucosa" EXACT [OBOL:automatic]
synonym: "small bowel mucosa of organ" EXACT [OBOL:automatic]
synonym: "small bowel mucous membrane" EXACT [OBOL:automatic]
synonym: "small bowel organ mucosa" EXACT [OBOL:automatic]
synonym: "small intestinal mucosa" EXACT []
synonym: "small intestine mucosa" EXACT []
synonym: "small intestine mucosa of organ" EXACT [OBOL:automatic]
synonym: "small intestine mucous membrane" EXACT []
synonym: "small intestine organ mucosa" EXACT [OBOL:automatic]
synonym: "tunica mucosa (intestinum tenue)" EXACT []
synonym: "tunica mucosa intestini tenuis" EXACT OMO:0003011 [FMA:14933, FMA:TA]
xref: BTO:0001259
xref: CALOHA:TS-0941
xref: EMAPA:35780
xref: FMA:14933
xref: MA:0002686
xref: NCIT:C33568
xref: SCTID:362144000
xref: UMLS:C0227261 {source="ncithesaurus:Small_Intestinal_Mucosa"}
is_a: UBERON:0001242 ! intestinal mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0001168 ! wall of small intestine
relationship: part_of UBERON:0001242 ! intestinal mucosa

[Term]
id: UBERON:0001205
name: submucosa of small intestine
namespace: uberon
def: "Submucosal tissue in the small intestines." [Wikipedia:Small_intestinal_submucosa]
subset: uberon_slim
synonym: "small bowel submucosa" EXACT [OBOL:automatic]
synonym: "small intestinal submucosa" EXACT []
synonym: "small intestine submucosa" EXACT []
synonym: "submucosa of small bowel" EXACT [OBOL:automatic]
synonym: "tela submucosa (intestinum tenue)" EXACT []
synonym: "tela submucosa intestini tenuis" EXACT OMO:0003011 [BTO:0002112]
xref: BTO:0002112
xref: EMAPA:37564 {source="MA:th"}
xref: FMA:14934
xref: MA:0001562
xref: NCIT:C33572
xref: SCTID:691000
xref: UMLS:C0227268 {source="ncithesaurus:Small_Intestinal_Submucosa"}
xref: Wikipedia:Small_intestinal_submucosa
is_a: UBERON:0009566 ! intestinal submucosa
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0001168 ! wall of small intestine

[Term]
id: UBERON:0001206
name: serosa of small intestine
namespace: uberon
def: "A serous membrane that is part of a small intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "serosa of small bowel" EXACT [OBOL:automatic]
synonym: "serous coat of small intestine" EXACT []
synonym: "serous membrane of small bowel" EXACT [OBOL:automatic]
synonym: "serous membrane of small intestine" EXACT [OBOL:automatic]
synonym: "small bowel serosa" EXACT [OBOL:automatic]
synonym: "small bowel serous membrane" EXACT [OBOL:automatic]
synonym: "small intestinal serosa" EXACT []
synonym: "small intestine serosa" EXACT []
synonym: "small intestine serous membrane" EXACT [OBOL:automatic]
synonym: "tunica serosa (intestinum tenue)" EXACT []
synonym: "tunica serosa intestini tenuis" EXACT OMO:0003011 [FMA:14938, FMA:TA]
synonym: "visceral peritoneum of small intestine" EXACT []
xref: EMAPA:37561 {source="MA:th"}
xref: FMA:14938
xref: MA:0001558
xref: SCTID:8266009
is_a: UBERON:0001243 ! serosa of intestine
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0001168 ! wall of small intestine
relationship: part_of UBERON:0001243 ! serosa of intestine
property_value: UBPROP:0000010 "duodenum, 1st part serosa, 2nd - 4th adventitia" xsd:string

[Term]
id: UBERON:0001207
name: mucosa of large intestine
namespace: uberon
def: "A mucosa that is part of a large intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "large intestinal mucosa" EXACT []
synonym: "large intestine mucosa" EXACT []
synonym: "large intestine mucosa of organ" EXACT [OBOL:automatic]
synonym: "large intestine mucous membrane" EXACT [OBOL:automatic]
synonym: "large intestine organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of organ of large intestine" EXACT [OBOL:automatic]
synonym: "mucous membrane of large intestine" EXACT []
synonym: "organ mucosa of large intestine" EXACT [OBOL:automatic]
synonym: "tunica mucosa intestini crassi" EXACT OMO:0003011 [FMA:14969, FMA:TA]
xref: CALOHA:TS-2106
xref: EMAPA:35467
xref: FMA:14969
xref: MA:0002688
xref: NCIT:C32926
xref: UMLS:C0734203 {source="ncithesaurus:Large_Intestinal_Mucosa"}
is_a: UBERON:0001242 ! intestinal mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000059 ! large intestine
relationship: part_of UBERON:0001169 ! wall of large intestine
relationship: part_of UBERON:0001242 ! intestinal mucosa

[Term]
id: UBERON:0001208
name: submucosa of large intestine
namespace: uberon
def: "A submucosa that is part of a large intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "large intestinal submucosa" EXACT []
synonym: "large intestine submucosa" EXACT []
synonym: "submucous layer of large intestine" RELATED [BTO:0002111]
synonym: "tela submucosa intestini crassi" EXACT OMO:0003011 [FMA:14970, FMA:TA]
xref: BTO:0002111
xref: EMAPA:37560 {source="MA:th"}
xref: FMA:14970
xref: MA:0002690
xref: NCIT:C32930
xref: UMLS:C0734204 {source="ncithesaurus:Large_Intestinal_Submucosa"}
is_a: UBERON:0009566 ! intestinal submucosa
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0000059 ! large intestine
relationship: part_of UBERON:0001169 ! wall of large intestine

[Term]
id: UBERON:0001209
name: serosa of large intestine
namespace: uberon
def: "A serous membrane that is part of a large intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "large intestinal serosa" EXACT []
synonym: "large intestine serosa" EXACT []
synonym: "large intestine serous membrane" EXACT [OBOL:automatic]
synonym: "serous coat of large intestine" EXACT []
synonym: "serous membrane of large intestine" EXACT [OBOL:automatic]
synonym: "tunica serosa intestini crassi" EXACT OMO:0003011 [FMA:14975, FMA:TA]
synonym: "visceral peritoneum of large intestine" EXACT []
xref: EMAPA:37557 {source="MA:th"}
xref: FMA:14975
xref: MA:0001546
xref: NCIT:C32929
xref: UMLS:C1517727 {source="ncithesaurus:Large_Intestinal_Serosal_Surface"}
is_a: UBERON:0001243 ! serosa of intestine
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0000059 ! large intestine
relationship: part_of UBERON:0001169 ! wall of large intestine
relationship: part_of UBERON:0001243 ! serosa of intestine
property_value: editor_note "TODO - check serosa/peritoneum" xsd:string

[Term]
id: UBERON:0001212
name: duodenal gland
namespace: uberon
def: "A compound tubular submucosal gland found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate)[WP]." [Wikipedia:Brunner's_glands]
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "Brunner's gland" EXACT [FMA:15060]
synonym: "gland of Brunner" EXACT [FMA:15060]
synonym: "glandula duodenales" RELATED OMO:0003011 [BTO:0002376]
synonym: "glandula duodenales Brunneri" RELATED OMO:0003011 [BTO:0002376]
synonym: "submucosal gland of duodenum" EXACT []
xref: BTO:0002376
xref: EMAPA:36522
xref: FMA:15060
xref: GAID:314
xref: MA:0001551
xref: MESH:D002011
xref: NCIT:C13010
xref: SCTID:41298001
xref: UMLS:C0006323 {source="ncithesaurus:Brunner_s_Gland"}
xref: Wikipedia:Brunner's_glands
is_a: UBERON:0003408 ! gland of digestive tract
is_a: UBERON:0011148 {notes="compound tubular"} ! submucosal gland
intersection_of: UBERON:0011148 ! submucosal gland
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: located_in UBERON:0003332 {source="FMA, modified"} ! submucosa of duodenum
relationship: only_in_taxon NCBITaxon:40674 {notes="unclear for Aves", source="ISBN:9780521617147"} ! Mammalia
relationship: part_of UBERON:0002114 ! duodenum
property_value: editor_note "currently defined as equivalent to any submucosal gland in the duodenum." xsd:string
property_value: UBPROP:0000008 "Said to be absent outside mammlian (Andrew 1959) but Ziswiler and Farner (1972) noted similar glands at the gastroduodenal junction of some birds" xsd:string {source="ISBN:9780521617147"}

[Term]
id: UBERON:0001213
name: intestinal villus
namespace: uberon
alt_id: UBERON:0007607
def: "The tiny hair-like projections that protrude from the inside of the small intestine that contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; the villi increase the absorptive surface area of the small intestine by approximately 30-fold." [MGI:csmith, MGI:rbabiuk, MP:0008108]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "enteric villi" EXACT OMO:0003004 [HP:0011473]
synonym: "enteric villous" EXACT [HP:0011473]
synonym: "enteric villus" EXACT [HP:0011473]
synonym: "intestinal villi" EXACT OMO:0003004 [ZFA:0005125]
synonym: "intestinal villus layer" RELATED []
synonym: "small intestine villus" RELATED [MA:0001563]
synonym: "villi intestinales" EXACT OMO:0003004 []
synonym: "villi intestinales" RELATED OMO:0003011 [Wikipedia:Intestinal_villus]
synonym: "villus" EXACT [BTO:0003121]
synonym: "villus intestinalis (intestinum tenue)" EXACT [FMA:15072]
xref: BTO:0003121
xref: EMAPA:35784
xref: FMA:15072
xref: MA:0001563
xref: NCIT:C33874
xref: SCTID:23230007
xref: TAO:0005125
xref: UMLS:C1519988 {source="ncithesaurus:Villus"}
xref: Wikipedia:Intestinal_villus
xref: ZFA:0005125
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004923 {source="FMA"} ! organ component layer
relationship: has_part UBERON:0001981 ! blood vessel
relationship: has_part UBERON:0012425 ! striated border microvillus layer
relationship: part_of UBERON:0001204 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="may be present in other parts in other species", source="FMA"} ! mucosa of small intestine
relationship: part_of UBERON:0001277 {source="ZFA"} ! intestinal epithelium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/38/Small_intestine_low_mag.jpg" xsd:anyURI
property_value: editor_note "in mammals, villi are (largely?) absent from the large intestine, so we treat this as equivalent to small intestinal villus. small/large subdivision may not make sense for all species for which this is present (see ZFA). Note that VHOG quotes ISBN:978-0030223693 as suggesting there are some villi in the large intestine" xsd:string
property_value: UBPROP:0000001 "The entire digestive tract is lined by well developed villi, which are longest in the intestinal bulb and decrease progressively in size towards the caudal end of the intestine. No crypts are present, but, the regions between the villi, the intervillus pockets, have a crypt-like function. Cells are produced in the intervillus pockets and shed from the villus tips. Crosnier et al. 2005[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005125", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000012 "the BTO class refers to a generic villous" xsd:string {external_ontology="BTO"}

[Term]
id: UBERON:0001215
name: inferior mesenteric vein
namespace: uberon
def: "A blood vessel that drains blood from the large intestine that usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV). Anatomical variations include the IMV draining into the confluence of the SMV and splenic vein and the IMV draining in the SMV. The IMV lies to the right of the similarly name artery, the inferior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]." [Wikipedia:Inferior_mesenteric_vein]
subset: human_reference_atlas
subset: uberon_slim
synonym: "lower mesenteric vein" RELATED [BTO:0002782]
synonym: "vena mesenterica inferior" RELATED OMO:0003011 [Wikipedia:Inferior_mesenteric_vein]
xref: BTO:0002782
xref: EHDAA2:0000819
xref: EHDAA:8712
xref: EMAPA:18642
xref: FMA:15391
xref: MA:0002178
xref: NCIT:C32782
xref: SCTID:281055007
xref: UMLS:C0226754 {source="ncithesaurus:Inferior_Mesenteric_Vein"}
xref: VHOG:0001118
xref: Wikipedia:Inferior_mesenteric_vein
is_a: UBERON:0005617 ! mesenteric vein
intersection_of: UBERON:0005617 ! mesenteric vein
intersection_of: drains UBERON:0000059 ! large intestine
relationship: drains UBERON:0000059 ! large intestine
relationship: tributary_of UBERON:0003713 {source="FMA/obol"} ! splenic vein
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001222
name: right ureter
namespace: uberon
def: "An ureter that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:37373 {source="MA:th"}
xref: FMA:15571
xref: MA:0001685
xref: NCIT:C49327
xref: SCTID:276251000
xref: UMLS:C0227682 {source="ncithesaurus:Right_Ureter"}
is_a: UBERON:0000056 ! ureter
intersection_of: UBERON:0000056 ! ureter
intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism
relationship: in_right_side_of UBERON:0000468 ! multicellular organism
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Ureter_R.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Ureter_R.glb" xsd:anyURI
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0001223
name: left ureter
namespace: uberon
def: "An ureter that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:37372 {source="MA:th"}
xref: FMA:15572
xref: MA:0001684
xref: NCIT:C49324
xref: SCTID:276340002
xref: UMLS:C0227683 {source="ncithesaurus:Left_Ureter"}
is_a: UBERON:0000056 ! ureter
intersection_of: UBERON:0000056 ! ureter
intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Ureter_L.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Ureter_L.glb" xsd:anyURI
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0001224
name: renal pelvis
namespace: uberon
def: "A funnel shaped proximal portion of the ureter that is formed by convergence of the major calices [MP]." [MP:0004194]
comment: In this ontology, the renal pelvis is represented as the area of part-overlap between the kidney and the ureter
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "kidney pelvis" EXACT []
synonym: "p. renallis" RELATED OMO:0003011 [Wikipedia:Renal_pelvis]
synonym: "pelvis of ureter" EXACT []
synonym: "pyelum" RELATED [MP:0004194]
xref: CALOHA:TS-2230
xref: EMAPA:17948
xref: FMA:15575
xref: GAID:426
xref: galen:RenalPelvis
xref: MA:0000374
xref: MESH:D007682
xref: NCIT:C12887
xref: SCTID:362221007
xref: UMLS:C0227666 {source="ncithesaurus:Renal_Pelvis"}
xref: Wikipedia:Renal_pelvis
is_a: UBERON:0000064 ! organ part
is_a: UBERON:0004111 ! anatomical conduit
disjoint_from: UBERON:0002355 ! pelvic region of trunk
relationship: channel_for UBERON:0001088 ! urine
relationship: channels_from UBERON:0002113 ! kidney
relationship: channels_into UBERON:0000056 ! ureter
relationship: continuous_with UBERON:0000056 {source="FMA"} ! ureter
relationship: contributes_to_morphology_of UBERON:0000056 ! ureter
relationship: part_of UBERON:0002113 {source="MA"} ! kidney
relationship: part_of UBERON:0036295 ! renal pelvis/ureter
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/c/c0/Illu_kidney2.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001225
name: cortex of kidney
namespace: uberon
def: "Outer cortical portion of the kidney, between the renal capsule and the renal medulla." [Wikipedia:Renal_cortex]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "cortex renalis" EXACT OMO:0003011 [FMA:15581, FMA:TA]
synonym: "kidney cortex" EXACT []
synonym: "renal cortex" EXACT []
xref: BTO:0001166
xref: CALOHA:TS-0503
xref: EMAPA:17952
xref: FMA:15581
xref: GAID:424
xref: galen:CortexOfKidney
xref: MA:0000372
xref: MESH:D007672
xref: NCIT:C12739
xref: SCTID:362211004
xref: UMLS:C0022655 {source="ncithesaurus:Renal_Cortex"}
xref: Wikipedia:Renal_cortex
is_a: UBERON:0001851 ! cortex
intersection_of: UBERON:0001851 ! cortex
intersection_of: part_of UBERON:0002113 ! kidney
relationship: contributes_to_morphology_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0008987 {source="FMA"} ! renal parenchyma
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Kidney_L.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Kidney_R.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_L.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_R.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000010 "In the adult metanephros, it forms a continuous smooth outer zone with a number of projections that extend down between the pyramids. It contains the renal corpuscles and the renal tubules except for parts of the loop of Henle which descend into the renal medulla. It also contains blood vessels and cortical collecting ducts. The renal cortex is the part of the kidney where ultrafiltration occurs.[WP]" xsd:string

[Term]
id: UBERON:0001231
name: nephron tubule
namespace: uberon
alt_id: UBERON:0004210
def: "An epithelial tube that is part of the nephron, the functional part of the kidney." [GO:0072078, Wikipedia:Renal_tubule]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "kidney tubule" EXACT [GAID:433]
synonym: "renal tubule" BROAD []
synonym: "tubulus renalis" EXACT []
synonym: "uriniferous tubule" RELATED [MA:0000377]
xref: BTO:0000343
xref: CALOHA:TS-1262
xref: EFO:0003666
xref: EMAPA:27782
xref: EV:0100387
xref: FMA:15627
xref: GAID:433
xref: MA:0000377
xref: MESH:D007684
xref: NCIT:C49274
xref: SCTID:361332007
xref: TAO:0001287
xref: UMLS:C0022674 {source="ncithesaurus:Renal_Tubule"}
xref: Wikipedia:Renal_tubule
xref: ZFA:0001287
is_a: UBERON:0004211 ! nephron epithelium
is_a: UBERON:0009773 {source="GO"} ! renal tubule
intersection_of: UBERON:0003914 {source="GO", source="MA", source="ZFA"} ! epithelial tube
intersection_of: part_of UBERON:0001285 {source="GO", source="MA", source="ZFA"} ! nephron
relationship: contributes_to_morphology_of UBERON:0001285 ! nephron
relationship: develops_from UBERON:0003918 {notes="checkme"} ! kidney mesenchyme
relationship: has_part CL:0005009 {source="ZFA"} ! renal principal cell
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "note that in ISBN:0073040584 (Vertebrates, Kardong), the uriniferous tubule contains the nephron, so we have a separate class, rather than using a synonym, as in MA" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001232
name: collecting duct of renal tubule
namespace: uberon
def: "The collecting duct is a portion of the nephron through which water flows, moving passively down its concentration gradient." [GO:0072044, Wikipedia:Collecting_tubule]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "arcuate renal tubule" RELATED [Wikipedia:Connecting_tubule]
synonym: "collecting duct" EXACT [GO:0072044]
synonym: "collecting duct system" RELATED [BTO:0000761]
synonym: "collecting tubule" RELATED []
synonym: "junctional tube" RELATED [Wikipedia:Connecting_tubule]
synonym: "kidney collecting duct" EXACT []
synonym: "kidney collecting tubule" RELATED []
synonym: "renal collecting tubule" EXACT [FMA:15628]
synonym: "tubulus renalis arcuatus" EXACT OMO:0003011 [Wikipedia:Connecting_tubule]
synonym: "tubulus renalis colligens" EXACT []
synonym: "ureteric tree" RELATED [EMAPA:28407]
xref: BTO:0000761
xref: CALOHA:TS-0860
xref: EMAPA:28407
xref: EV:0100391
xref: FMA:15628
xref: GAID:434
xref: MA:0000371
xref: MESH:D007685
xref: SCTID:28202009
xref: TAO:0005294
xref: Wikipedia:Collecting_tubule
xref: ZFA:0005294
is_a: UBERON:0006555 ! excretory tube
relationship: contributes_to_morphology_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0001285 {notes="checkme", source="GO"} ! nephron
relationship: part_of UBERON:0004100 ! renal collecting system
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Renal duct that collects the output from renal tubules.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005294", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000012 "in ISBN:0073040584 (Vertebrates, Kardong), the nephron is adjacent to the collecting tubule, consistent with FMA, but not GO. Wikipedia says: Many sources include the connecting tubule as part of the collecting duct system. However, the embryological origin is more similar to the nephron than it is to the rest of the collecting duct (which derives from the ureteric bud), and other sources therefore classify the connecting tubule with the nephron" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001238
name: lamina propria of small intestine
namespace: uberon
def: "Lamina propria that is part_of the small intestine." [GOC:Obol]
synonym: "lamina propria mucosa of small bowel" EXACT [OBOL:automatic]
synonym: "lamina propria mucosa of small intestine" EXACT [OBOL:automatic]
synonym: "lamina propria mucosae of small bowel" EXACT [OBOL:automatic]
synonym: "lamina propria mucosae of small intestine" EXACT []
synonym: "lamina propria of mucosa of small intestine" EXACT []
synonym: "lamina propria of small bowel" EXACT [OBOL:automatic]
synonym: "small bowel lamina propria" EXACT [OBOL:automatic]
synonym: "small bowel lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "small bowel lamina propria mucosae" EXACT [OBOL:automatic]
synonym: "small intestine lamina propria" EXACT []
synonym: "small intestine lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "small intestine lamina propria mucosae" EXACT [OBOL:automatic]
xref: EMAPA:35779
xref: FMA:15651
xref: MA:0001554
xref: NCIT:C49297
xref: SCTID:63588008
xref: UMLS:C1711325 {source="ncithesaurus:Small_Intestinal_Lamina_Propria"}
is_a: UBERON:0004780 ! gastrointestinal system lamina propria
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0001204 ! mucosa of small intestine

[Term]
id: UBERON:0001242
name: intestinal mucosa
namespace: uberon
def: "Mucosal layer that lines the intestine." [UBERON:cjm]
subset: pheno_slim
subset: uberon_slim
synonym: "bowel mucosa" EXACT [OBOL:automatic]
synonym: "bowel mucosa of organ" EXACT [OBOL:automatic]
synonym: "bowel mucous membrane" EXACT [OBOL:automatic]
synonym: "bowel organ mucosa" EXACT [OBOL:automatic]
synonym: "intestine mucosa" EXACT []
synonym: "intestine mucosa of organ" EXACT [OBOL:automatic]
synonym: "intestine mucous membrane" EXACT [OBOL:automatic]
synonym: "intestine organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of bowel" EXACT [OBOL:automatic]
synonym: "mucosa of intestine" EXACT []
synonym: "mucosa of organ of bowel" EXACT [OBOL:automatic]
synonym: "mucosa of organ of intestine" EXACT [OBOL:automatic]
synonym: "mucous membrane of bowel" EXACT [OBOL:automatic]
synonym: "mucous membrane of intestine" EXACT [OBOL:automatic]
synonym: "organ mucosa of bowel" EXACT [OBOL:automatic]
synonym: "organ mucosa of intestine" EXACT [OBOL:automatic]
synonym: "tunica mucosa intestini" EXACT []
xref: BTO:0000642
xref: EMAPA:35440
xref: FMA:15695
xref: GAID:296
xref: MA:0001537
xref: MESH:D007413
xref: NCIT:C49241
xref: SCTID:362080002
xref: UMLS:C0021839 {source="ncithesaurus:Intestinal_Mucosa"}
is_a: UBERON:0004786 ! gastrointestinal system mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0001262 ! wall of intestine

[Term]
id: UBERON:0001243
name: serosa of intestine
namespace: uberon
def: "A serous membrane that is part of a wall of intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "anatomical wall of bowel serosa" EXACT [OBOL:automatic]
synonym: "anatomical wall of bowel serous membrane" EXACT [OBOL:automatic]
synonym: "anatomical wall of intestine serosa" EXACT [OBOL:automatic]
synonym: "anatomical wall of intestine serous membrane" EXACT [OBOL:automatic]
synonym: "bowel anatomical wall serosa" EXACT [OBOL:automatic]
synonym: "bowel anatomical wall serous membrane" EXACT [OBOL:automatic]
synonym: "bowel wall serosa" EXACT [OBOL:automatic]
synonym: "bowel wall serous membrane" EXACT [OBOL:automatic]
synonym: "intestinal serosa" EXACT []
synonym: "intestinal wall serosa" EXACT [OBOL:automatic]
synonym: "intestinal wall serous membrane" EXACT [OBOL:automatic]
synonym: "intestine anatomical wall serosa" EXACT [OBOL:automatic]
synonym: "intestine anatomical wall serous membrane" EXACT [OBOL:automatic]
synonym: "intestine serosa" EXACT []
synonym: "intestine wall serosa" EXACT [OBOL:automatic]
synonym: "intestine wall serous membrane" EXACT [OBOL:automatic]
synonym: "serosa of anatomical wall of bowel" EXACT [OBOL:automatic]
synonym: "serosa of anatomical wall of intestine" EXACT [OBOL:automatic]
synonym: "serosa of bowel anatomical wall" EXACT [OBOL:automatic]
synonym: "serosa of bowel wall" EXACT [OBOL:automatic]
synonym: "serosa of intestinal wall" EXACT [OBOL:automatic]
synonym: "serosa of intestine anatomical wall" EXACT [OBOL:automatic]
synonym: "serosa of intestine wall" EXACT [OBOL:automatic]
synonym: "serosa of wall of bowel" EXACT [OBOL:automatic]
synonym: "serosa of wall of intestine" EXACT [OBOL:automatic]
synonym: "serous membrane of anatomical wall of bowel" EXACT [OBOL:automatic]
synonym: "serous membrane of anatomical wall of intestine" EXACT [OBOL:automatic]
synonym: "serous membrane of bowel anatomical wall" EXACT [OBOL:automatic]
synonym: "serous membrane of bowel wall" EXACT [OBOL:automatic]
synonym: "serous membrane of intestinal wall" EXACT [OBOL:automatic]
synonym: "serous membrane of intestine anatomical wall" EXACT [OBOL:automatic]
synonym: "serous membrane of intestine wall" EXACT [OBOL:automatic]
synonym: "serous membrane of wall of bowel" EXACT [OBOL:automatic]
synonym: "serous membrane of wall of intestine" EXACT [OBOL:automatic]
synonym: "visceral peritoneum of intestine" EXACT []
synonym: "wall of bowel serosa" EXACT [OBOL:automatic]
synonym: "wall of bowel serous membrane" EXACT [OBOL:automatic]
synonym: "wall of intestine serosa" EXACT [OBOL:automatic]
synonym: "wall of intestine serous membrane" EXACT [OBOL:automatic]
xref: EMAPA:37619 {source="MA:th"}
xref: FMA:15701
xref: MA:0001538
is_a: UBERON:0004782 ! gastrointestinal system serosa
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0001262 ! wall of intestine
property_value: editor_note "TODO - check serosa/peritoneum" xsd:string

[Term]
id: UBERON:0001245
name: anus
namespace: uberon
def: "Orifice at the opposite end of an animal's digestive tract from the mouth. Its function is to expel feces, unwanted semi-solid matter produced during digestion, which, depending on the type of animal, may be one or more of: matter which the animal cannot digest, such as bones; food material after all the nutrients have been extracted, for example cellulose or lignin; ingested matter which would be toxic if it remained in the digestive tract; and dead or excess gut bacteria and other endosymbionts." [Wikipedia:Anus, ZFIN:curator]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "anal opening" EXACT []
synonym: "anal orifice" EXACT []
synonym: "opening of terminal part of digestive tract" EXACT []
synonym: "proctodeum" RELATED []
xref: BTO:0001680
xref: CALOHA:TS-2005
xref: EV:0100082
xref: FBbt:00047153 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:15711
xref: GAID:312
xref: galen:Anus
xref: MA:0000331
xref: NCIT:C43362
xref: SCTID:181262009
xref: TADS:0000066
xref: TGMA:0001279
xref: UMLS:C0003461 {source="ncithesaurus:Anus"}
xref: WBbt:0005364
xref: Wikipedia:Anus
is_a: UBERON:0000161 ! orifice
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000161 ! orifice
intersection_of: distalmost_part_of UBERON:0001555 ! digestive tract
relationship: develops_from UBERON:0000931 ! proctodeum
relationship: distalmost_part_of UBERON:0001555 ! digestive tract
relationship: part_of UBERON:0001555 ! digestive tract
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/65/Protovsdeuterostomes.svg" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/75/Anorectum.gif" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000007 "anal" xsd:string
property_value: UBPROP:0000008 "In the lungfish, sharks and rays the rectum opens into the cloaca which also receives wastes (urine) from the kidneys and material from the reproductive organs. In bony fish the rectum reaches the outside environment through the anus, which is normally situated just in front the urinary and reproductive openings. However in some fish the digestive tract may be curled back on itself, and in the Electric Eel (Electrophorus electricus) the anus is situated in the fish's throat. -- http://www.earthlife.net/fish/digestion.html" xsd:string

[Term]
id: UBERON:0001246
name: interlobular bile duct
namespace: uberon
def: "The canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad." [MP:0009500]
subset: pheno_slim
synonym: "interlobular ductule" EXACT [MP:0009500]
xref: FMA:15767
xref: MA:0002668
xref: NCIT:C32827
xref: SCTID:83488001
xref: UMLS:C0227515 {source="ncithesaurus:Interlobular_Bile_Duct"}
xref: Wikipedia:Interlobular_bile_ducts
is_a: UBERON:0003704 {source="FMA", source="MA-part-of"} ! intrahepatic bile duct
relationship: connects UBERON:0004058 ! biliary ductule
relationship: connects UBERON:0014719 ! intralobular duct
relationship: contributes_to_morphology_of UBERON:0001279 ! portal triad
relationship: part_of UBERON:0001279 {source="FMA", source="MA", source="MP"} ! portal triad

[Term]
id: UBERON:0001252
name: adventitia of ureter
namespace: uberon
def: "An adventitia that is part of a ureter." [OBOL:automatic]
synonym: "external adventitia of ureter" EXACT []
synonym: "tunica adventitia (ureter)" EXACT OMO:0003011 [FMA:15892, FMA:TA]
synonym: "tunica adventitia ureteris" EXACT OMO:0003011 [FMA:15892, FMA:TA]
synonym: "ureter adventitia" EXACT []
synonym: "ureteral adventitia" EXACT []
xref: EMAPA:28114
xref: FMA:15892
xref: MA:0002652
xref: SCTID:392273001
xref: SCTID:47879001
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005742 ! adventitia
intersection_of: UBERON:0005742 ! adventitia
intersection_of: part_of UBERON:0000056 ! ureter
relationship: part_of UBERON:0009916 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of ureter

[Term]
id: UBERON:0001253
name: lamina propria of ureter
namespace: uberon
def: "A lamina propria that is part of a ureter [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "lamina propria mucosa of ureter" EXACT [OBOL:automatic]
synonym: "lamina propria mucosae of ureter" EXACT [OBOL:automatic]
synonym: "ureter lamina propria" EXACT []
synonym: "ureter lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "ureter lamina propria mucosae" EXACT [OBOL:automatic]
xref: EMAPA:28841
xref: FMA:15896
xref: MA:0002653
xref: SCTID:2771005
is_a: UBERON:0000030 ! lamina propria
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0000056 ! ureter
relationship: part_of UBERON:0004980 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mucosa of ureter
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001255
name: urinary bladder
namespace: uberon
def: "Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]." [MGI:anna, Wikipedia:Urinary_bladder]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "bladder" BROAD [EHDAA2:0000174]
synonym: "urocyst" RELATED [Wikipedia:Urinary_bladder]
synonym: "vesica" RELATED [BTO:0001418]
synonym: "vesica urinaria" EXACT OMO:0003011 [Wikipedia:Urinary_bladder]
xref: AAO:0000623
xref: BTO:0001418
xref: CALOHA:TS-1090
xref: EFO:0000290
xref: EHDAA2:0000174
xref: EHDAA:9328
xref: EMAPA:18321
xref: EV:0100098
xref: FMA:15900
xref: GAID:0000004
xref: galen:UrinaryBladder
xref: MA:0000380
xref: MAT:0000122
xref: MESH:D001743
xref: MIAA:0000122
xref: NCIT:C12414
xref: SCTID:302512001
xref: UMLS:C0005682 {source="ncithesaurus:Bladder"}
xref: VHOG:0000740
xref: Wikipedia:Urinary_bladder
xref: XAO:0000154
is_a: UBERON:0002075 ! viscus
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0018707 {source="BTO"} ! bladder organ
relationship: develops_from UBERON:0000164 {notes="upper part of UG sinus"} ! primitive urogenital sinus
relationship: part_of UBERON:0001556 {source="FMA"} ! lower urinary tract
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Urinary_Bladder.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Urinary_Bladder.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg" xsd:anyURI
property_value: RO:0002161 NCBITaxon:8782 {editor="https://orcid.org/0000-0003-3308-6245", id="GOTAX:0010073", source="https://github.com/obophenotype/uberon/issues/454"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A saccular organ in which urine accumulates before discharge from the body. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000740", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000001 "Anatomical structure which consists of a membranous sac used to temporarily store urine until it is excreted from the body.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000623", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "In tetrapods, the urinary bladder arises as an outpocketing of the cloaca. (...) The tetrapod urinary bladder appears first among amphibians and is present in Sphenodon, turtles, most lizards, ostriches among birds, and all mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000740", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.577-78", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "vesical" xsd:string
property_value: UBPROP:0000008 "The urinary bladder evolved in tetrapods. Birds to not possess a true urinary bladder, although Palaeognathae have an undifferentiated cloacal outpocketing that serves a similar function[https://github.com/obophenotype/uberon/issues/454]" xsd:string

[Term]
id: UBERON:0001256
name: wall of urinary bladder
namespace: uberon
def: "An anatomical wall that lines the insider of a urinary bladder." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
synonym: "anatomical wall of bladder" EXACT [OBOL:automatic]
synonym: "anatomical wall of urinary bladder" EXACT [OBOL:automatic]
synonym: "bladder anatomical wall" EXACT [OBOL:automatic]
synonym: "bladder wall" EXACT [OBOL:automatic]
synonym: "urinary bladder anatomical wall" EXACT [OBOL:automatic]
synonym: "urinary bladder wall" EXACT []
synonym: "wall of bladder" EXACT [OBOL:automatic]
xref: BTO:0001462
xref: EMAPA:35175
xref: FMA:15902
xref: MA:0002493
xref: NCIT:C48941
xref: SCTID:362225003
xref: UMLS:C0458421 {source="ncithesaurus:Bladder_Wall"}
is_a: UBERON:0000060 ! anatomical wall
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001255 ! urinary bladder
relationship: part_of UBERON:0001255 ! urinary bladder
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001259
name: mucosa of urinary bladder
namespace: uberon
def: "The mucous membrane lining the urinary bladder." [MGI:anna, MP:0011766]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
synonym: "bladder mucosa" EXACT []
synonym: "bladder mucous membrane" EXACT [OBOL:automatic]
synonym: "bladder organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of bladder" EXACT [OBOL:automatic]
synonym: "mucous membrane of bladder" EXACT []
synonym: "mucous membrane of urinary bladder" EXACT []
synonym: "tunica mucosa (vesica urinaria)" EXACT OMO:0003011 [FMA:15928, FMA:TA]
synonym: "tunica mucosa vesicae" EXACT OMO:0003011 [FMA:15928, FMA:TA]
synonym: "tunica mucosa vesicae urinariae" EXACT [MP:MP]
synonym: "urinary bladder mucosa" EXACT []
synonym: "urinary bladder mucous membrane" EXACT [OBOL:automatic]
xref: EFO:0000293
xref: EMAPA:35897
xref: FMA:15928
xref: galen:MucousMembraneOfUrinaryBladder
xref: MA:0001692
xref: NCIT:C32205
xref: SCTID:362224004
xref: UMLS:C0227691 {source="ncithesaurus:Bladder_Mucosa"}
is_a: UBERON:0000344 ! mucosa
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001255 ! urinary bladder
relationship: contributes_to_morphology_of UBERON:0001255 ! urinary bladder
relationship: part_of UBERON:0001256 ! wall of urinary bladder
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001260
name: serosa of urinary bladder
namespace: uberon
def: "A serous membrane that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic]
synonym: "bladder serosa" EXACT []
synonym: "bladder serous membrane" EXACT [OBOL:automatic]
synonym: "serosa of bladder" EXACT []
synonym: "serous coat of bladder" EXACT []
synonym: "serous coat of urinary bladder" EXACT []
synonym: "serous membrane of bladder" EXACT [OBOL:automatic]
synonym: "serous membrane of urinary bladder" EXACT [OBOL:automatic]
synonym: "tunica serosa (vesica urinaria)" EXACT OMO:0003011 [FMA:15932, FMA:TA]
synonym: "tunica serosa vesicae" EXACT OMO:0003011 [FMA:15932, FMA:TA]
synonym: "urinary bladder serosa" EXACT []
synonym: "urinary bladder serous membrane" EXACT [OBOL:automatic]
synonym: "visceral peritoneum of urinary bladder" EXACT []
xref: EMAPA:28661
xref: FMA:15932
xref: MA:0001696
xref: SCTID:5868002
is_a: UBERON:0000042 ! serous membrane
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0001255 ! urinary bladder
relationship: part_of UBERON:0001256 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of urinary bladder
property_value: editor_note "TODO - check serosa/peritoneum" xsd:string

[Term]
id: UBERON:0001261
name: lamina propria of urinary bladder
namespace: uberon
def: "A lamina propria that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "bladder lamina propria" EXACT [OBOL:automatic]
synonym: "bladder lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "bladder lamina propria mucosae" EXACT [OBOL:automatic]
synonym: "lamina propria mucosa of bladder" EXACT [OBOL:automatic]
synonym: "lamina propria mucosa of urinary bladder" EXACT [OBOL:automatic]
synonym: "lamina propria mucosae of bladder" EXACT [OBOL:automatic]
synonym: "lamina propria mucosae of urinary bladder" EXACT [OBOL:automatic]
synonym: "lamina propria of bladder" EXACT [OBOL:automatic]
synonym: "urinary bladder lamina propria" EXACT []
synonym: "urinary bladder lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "urinary bladder lamina propria mucosae" EXACT [OBOL:automatic]
xref: EMAPA:30088
xref: FMA:15935
xref: MA:0001695
xref: NCIT:C48940
xref: UMLS:C1706967 {source="ncithesaurus:Bladder_Lamina_Propria"}
is_a: UBERON:0000030 ! lamina propria
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0001255 ! urinary bladder
relationship: part_of UBERON:0001259 ! mucosa of urinary bladder
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000010 "Contains loose to dense connective tissue, variably sized blood vessels that may be close to epithelium, lymphatics, variable adipose tissue" xsd:string

[Term]
id: UBERON:0001262
name: wall of intestine
namespace: uberon
def: "An anatomical wall that is part of a intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "anatomical wall of bowel" EXACT [OBOL:automatic]
synonym: "anatomical wall of intestine" EXACT [OBOL:automatic]
synonym: "bowel anatomical wall" EXACT [OBOL:automatic]
synonym: "bowel wall" EXACT [OBOL:automatic]
synonym: "bowel wall" RELATED [MA:0001525]
synonym: "intestinal wall" EXACT []
synonym: "intestine anatomical wall" EXACT [OBOL:automatic]
synonym: "intestine wall" EXACT []
synonym: "wall of bowel" EXACT [OBOL:automatic]
xref: BTO:0000647
xref: EMAPA:35444
xref: FMA:15949
xref: MA:0001525
xref: MA:0002693
xref: NCIT:C49478
xref: UMLS:C1708548 {source="ncithesaurus:Intestinal_Wall_Tissue"}
is_a: UBERON:0000328 ! gut wall
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0000160 ! intestine
property_value: editor_note "we place two MA classes here due to the official ncit2ma mapping to intestinal wall tissue; not clear how bowel and intestine are different" xsd:string

[Term]
id: UBERON:0001263
name: pancreatic acinus
namespace: uberon
def: "The secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct." [MP:0009145]
subset: human_reference_atlas
subset: pheno_slim
synonym: "acinus pancreaticus" EXACT OMO:0003011 [FMA:16011]
synonym: "pancreas acinus" EXACT []
synonym: "pancreatic acinar" RELATED []
synonym: "pancreatic acini" RELATED OMO:0003004 []
xref: BTO:0000028 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: EMAPA:35651
xref: FMA:16011
xref: MA:0002417
xref: NCIT:C49268
xref: SCTID:247604006
xref: UMLS:C0227578 {source="ncithesaurus:Pancreatic_Acinus"}
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0013232 ! serous acinus
intersection_of: UBERON:0009842 ! glandular acinus
intersection_of: part_of UBERON:0000017 ! exocrine pancreas
relationship: composed_primarily_of CL:0002064 ! pancreatic acinar cell
relationship: contributes_to_morphology_of UBERON:0000017 ! exocrine pancreas
relationship: part_of UBERON:0007324 {source="FMA"} ! pancreatic lobule
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001264
name: pancreas
namespace: uberon
def: "An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO]." [GO:0031016]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
xref: AAO:0010112
xref: BTO:0000988
xref: CALOHA:TS-0736
xref: EFO:0000855
xref: EHDAA2:0001367
xref: EHDAA:6893
xref: EMAPA:17503
xref: EV:0100092
xref: FMA:7198
xref: GAID:334
xref: galen:Pancreas
xref: MA:0000120
xref: MAT:0000075
xref: MESH:D010179
xref: MIAA:0000075
xref: NCIT:C12393
xref: SCTID:181277001
xref: TAO:0000140
xref: UMLS:C0030274 {source="ncithesaurus:Pancreas"}
xref: VHOG:0000050
xref: Wikipedia:Pancreas
xref: XAO:0000136
xref: ZFA:0000140
is_a: UBERON:0002075 ! viscus
relationship: has_developmental_contribution_from UBERON:0003923 {source="Wikipedia"} ! dorsal pancreatic bud
relationship: has_developmental_contribution_from UBERON:0003924 {source="Wikipedia"} ! ventral pancreatic bud
relationship: has_part UBERON:0000016 ! endocrine pancreas
relationship: has_part UBERON:0000017 {gci_relation="part_of", gci_filler="NCBITaxon:89593"} ! exocrine pancreas
relationship: only_in_taxon NCBITaxon:7742 {source="PMID:16417468"} ! Vertebrata <vertebrates>
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Pancreas.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Pancreas.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/7e/Blausen_0699_PancreasAnatomy2.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Organ which secretes a fluid containing enzymes that aid in the digestion of food.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010112", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000050", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "pancreatic" xsd:string
property_value: UBPROP:0000008 "As a secretory organ serving exocrine and endocrine functions, the pancreas is specific to the vertebrates[PMID:16417468] Hagfishes and lampreys are unique in the complete separation of their endocrine pancreas (islet or- gan) and their exocrine pancreas (50). The endocrine and exocrine pancreas are coassociated in crown gnathostomes (50). In Branchiostoma and Ciona, there is no diverticulum as there is in hagfishes, lampreys, and gnathostomes, only dispersed insulin-secreting cells in the walls of the gastrointestinal tract (51, 52)" xsd:string {source="PMID:20959416"}
property_value: UBPROP:0000008 "The zebrafish does not have a discrete pancreas. Exocrine pancreatic tissue can be found scattered along the intestinal tract. The acinar structure of the exocrine pancreas is very similar to that of mammals and comprises cells with a very dark, basophilic cytoplasm" xsd:string
property_value: UBPROP:0000009 "The mature pancreas of higher vertebrates and mammals comprises two major functional units: the exocrine pancreas, which is responsible for the production of digestive enzymes to be secreted into the gut lumen, and the endocrine pancreas, which has its role in the synthesis of several hormones with key regulatory functions in food uptake and metabolism. The exocrine portion constitutes the majority of the mass of the pancreas, and contains only two different cell types, the secretory acinar cells and the ductular cells. The endocrine portion, which comprises only 1-2% of the total mass, contains five different cell types, which are organized into mixed functional assemblies referred to as the islets of Langerhans" xsd:string {source="PMID:16417468"}

[Term]
id: UBERON:0001265
name: trabecula of spleen
namespace: uberon
def: "A trabecula that is part of a spleen." [OBOL:automatic]
subset: human_reference_atlas
synonym: "spleen trabeculum" EXACT []
synonym: "splenic trabecula" EXACT []
synonym: "trabeculae of spleen" EXACT OMO:0003004 []
xref: EMAPA:35808
xref: FMA:16027
xref: MA:0000758
xref: NCIT:C33607
xref: SCTID:61987002
xref: UMLS:C0229688 {source="ncithesaurus:Splenic_Trabecula"}
xref: Wikipedia:Trabeculae_of_spleen
is_a: UBERON:0000440 ! trabecula
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000440 ! trabecula
intersection_of: part_of UBERON:0002106 ! spleen
relationship: part_of UBERON:1000024 {source="FMA"} ! parenchyma of spleen
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001268
name: peritoneal fluid
namespace: uberon
def: "Transudate contained in the peritoneal cavity." [FMA:16515]
subset: pheno_slim
subset: uberon_slim
xref: BTO:0001031
xref: EMAPA:35683
xref: FMA:16515
xref: MA:0002531
xref: MESH:D001202 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: ncithesaurus:Peritoneal_Fluid
xref: Wikipedia:Peritoneal_fluid
is_a: UBERON:0007779 ! transudate
is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland
is_a: UBERON:0036217 ! coelomic fluid
intersection_of: UBERON:0007779 ! transudate
intersection_of: located_in UBERON:0001179 ! peritoneal cavity
relationship: located_in UBERON:0001179 ! peritoneal cavity

[Term]
id: UBERON:0001271
name: pelvic girdle region
namespace: uberon
def: "The organism subdivision that includes the pelvic girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pelvic girdle regions." [DOI:10.1002/dvdy.22617, FMA:16581, FMA:23217, https://groups.google.com/d/topic/obo-anatomy/h4R4xKmINrw/discussion, https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003]
subset: uberon_slim
subset: vertebrate_core
synonym: "girdle - pelvic" RELATED []
synonym: "pelvic girdle" RELATED INCONSISTENT []
xref: EMAPA:37862 {source="MA:th"}
xref: FMA:16581
xref: NCIT:C33291
xref: SCTID:360010001
xref: UMLS:C0684083 {source="ncithesaurus:Pelvic_Girdle"}
xref: VSAO:0000304
is_a: UBERON:0007823 ! appendage girdle region
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0007823 ! appendage girdle region
intersection_of: part_of UBERON:0010709 ! pelvic complex
disjoint_from: UBERON:0007832 ! pelvic girdle skeleton
relationship: has_skeleton UBERON:0007832 ! pelvic girdle skeleton
relationship: in_lateral_side_of UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0010709 ! pelvic complex
property_value: curator_notes "this class describes the subdivision of the limb/fin, NOT the skeleton within. See also: skeleton of pectoral girdle (UBERON:0007831). See also comments on obo-anatomy mail list. Note that even though the class includes soft tissue it is more restrictive than 'pelvis' which also includes structures in cavities etc. TODO this needs to be better documented" xsd:string
property_value: UBPROP:0000001 "Subdivision of lower limb or fin which links the limb/fin to the body[FMA,modified]. There is only one instance of the pelvic girdle region per organism.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000304", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"}

[Term]
id: UBERON:0001276
name: epithelium of stomach
namespace: uberon
def: "The epithelial layer of the stomach ." [MP:0000471]
subset: pheno_slim
synonym: "epithelial tissue of stomach" EXACT [OBOL:automatic]
synonym: "epithelial tissue of ventriculus" EXACT [OBOL:automatic]
synonym: "epithelium of ventriculus" EXACT [OBOL:automatic]
synonym: "gastric epithelium" RELATED [BTO:0000500]
synonym: "stomach epithelial tissue" EXACT [OBOL:automatic]
synonym: "stomach epithelium" EXACT [OBOL:automatic]
synonym: "ventriculus epithelial tissue" EXACT [OBOL:automatic]
synonym: "ventriculus epithelium" EXACT [OBOL:automatic]
xref: BTO:0000500
xref: CALOHA:TS-2068
xref: EHDAA2:0001918
xref: EMAPA:17023
xref: FMA:17091
xref: MA:0001610
xref: SCTID:64977002
xref: VHOG:0001433
is_a: UBERON:0000485 ! simple columnar epithelium
is_a: UBERON:0003350 ! epithelium of mucosa
is_a: UBERON:0004808 ! gastrointestinal system epithelium
is_a: UBERON:0015833 ! foregut epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000945 ! stomach
relationship: contributes_to_morphology_of UBERON:0001199 ! mucosa of stomach
relationship: part_of UBERON:0001199 ! mucosa of stomach
property_value: UBPROP:0000012 "in FMA this is classified as simple columnar, MA divides this into squamous and glandular" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001277
name: intestinal epithelium
namespace: uberon
def: "Epithelial layer that lines the intestine." [UBERON:cjm]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "bowel epithelial tissue" EXACT [OBOL:automatic]
synonym: "bowel epithelium" EXACT [OBOL:automatic]
synonym: "epithelial tissue of bowel" EXACT [OBOL:automatic]
synonym: "epithelial tissue of intestine" EXACT [OBOL:automatic]
synonym: "epithelium of bowel" EXACT [OBOL:automatic]
synonym: "epithelium of intestine" EXACT [OBOL:automatic]
synonym: "intestine epithelial tissue" EXACT [OBOL:automatic]
synonym: "intestine epithelium" RELATED []
synonym: "villous epithelium" NARROW [ZFA:0005124]
xref: BTO:0000781
xref: EMAPA:32873
xref: FMA:17229
xref: MA:0001536
xref: NCIT:C49240
xref: SCTID:266135004
xref: TAO:0005124
xref: UMLS:C0226890 {source="ncithesaurus:Intestinal_Epithelium"}
xref: Wikipedia:Intestinal_epithelium
xref: ZFA:0005124
is_a: UBERON:0000485 ! simple columnar epithelium
is_a: UBERON:0003350 ! epithelium of mucosa
is_a: UBERON:0003929 ! digestive tract epithelium
is_a: UBERON:0004808 ! gastrointestinal system epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000160 ! intestine
relationship: contributes_to_morphology_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0001242 ! intestinal mucosa
property_value: UBPROP:0000001 "Simple columnar epithelium that lines the intestine, sometimes pseudostratified, with absorptive brush-border cells and mucous goblet cells clearly visible. Crosnier et al. 2005[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005124", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0001278
name: epithelium of large intestine
namespace: uberon
def: "An epithelium that is part of a large intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of large intestine" EXACT [OBOL:automatic]
synonym: "large intestinal epithelium" EXACT []
synonym: "large intestine epithelial tissue" EXACT [OBOL:automatic]
synonym: "large intestine epithelium" EXACT []
xref: CALOHA:TS-2105
xref: EMAPA:35466
xref: FMA:17301
xref: MA:0001545
is_a: UBERON:0001277 ! intestinal epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000059 ! large intestine
relationship: part_of UBERON:0001207 ! mucosa of large intestine

[Term]
id: UBERON:0001279
name: portal triad
namespace: uberon
def: "A multi-organ-part structure that consists of three vessels of the portal lobule including the bile duct, a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MGI:csmith, MP:0008993]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "trias hepatica" EXACT []
synonym: "trias hepatica" RELATED OMO:0003011 [Wikipedia:Portal_triad]
xref: FMA:17523
xref: MA:0002499
xref: NCIT:C33342
xref: SCTID:362192000
xref: UMLS:C0227514 {source="ncithesaurus:Portal_Triad"}
xref: Wikipedia:Portal_triad
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0034921 ! multi organ part structure
relationship: contributes_to_morphology_of UBERON:0001171 ! portal lobule
relationship: has_part UBERON:0001193 ! hepatic artery
relationship: has_part UBERON:0002017 ! portal vein
relationship: has_part UBERON:0003704 ! intrahepatic bile duct
relationship: part_of UBERON:0001172 ! hepatic acinus
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/6/62/Portal_triad.JPG" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000013 "The misnomer 'portal triad' traditionally has included only the first three structures, and was named before lymphatic vessels were discovered in the structure. It can refer both to the largest branch of each of these vessels running inside the hepatoduodenal ligament, and to the smaller branches of these vessels inside the liver." xsd:string

[Term]
id: UBERON:0001280
name: liver parenchyma
namespace: uberon
alt_id: UBERON:0003223
def: "The functional units of the liver including the lobules." [MP:0008986]
subset: pheno_slim
synonym: "hepatic parenchyma" EXACT [FMA:17540]
synonym: "hepatic parenchyme" RELATED [VHOG:0000539]
synonym: "liver parenchyme" EXACT [XAO:0000454]
synonym: "parenchyma of liver" EXACT [FMA:17540]
xref: AAO:0010405
xref: EHDAA2:0001004
xref: EHDAA:2201
xref: EMAPA:17203
xref: FMA:17540
xref: MA:0000366
xref: NCIT:C32735
xref: SCTID:363535004
xref: UMLS:C0736268
xref: VHOG:0000539
xref: XAO:0000454
is_a: UBERON:0000353 ! parenchyma
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000353 ! parenchyma
intersection_of: part_of UBERON:0002107 ! liver
relationship: contributes_to_morphology_of UBERON:0002107 ! liver
relationship: develops_from UBERON:0008835 {source="XAO"} ! hepatic diverticulum
relationship: part_of UBERON:0002107 ! liver
property_value: UBPROP:0000003 "the (liver) tubular structure (dual layered parenchyma) appears to be conserved among all embryonic vertebrates (...) it is not unlikely that all vertebrate livers share the same fundamental functional unit.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000539", ontology="VHOG", source="DOI:10.1002/ar.20524 Hardman RC, Volz DC, Kullman SW, Hinton DE, An in vivo look at vertebrate liver architecture: three-dimensional reconstruction from Medaka (Oryzias latipes). The Anatomical Record (2007)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001281
name: hepatic sinusoid
namespace: uberon
alt_id: UBERON:0003275
def: "Wide thin-walled blood vessels in the liver. In mammals they have neither veinous or arterial markers." [Wikipedia:Hepatic_sinusoid, ZFIN:curator]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "hepatic sinusoids" RELATED []
synonym: "liver hepatic sinusoids" EXACT [EHDAA2:0000999]
synonym: "liver sinusoid" EXACT []
synonym: "liver sinusoidal blood vessel" EXACT [OBOL:automatic]
synonym: "sinusoid of liver" EXACT [OBOL:automatic]
synonym: "sinusoidal blood vessel of liver" EXACT [OBOL:automatic]
synonym: "vas capillare sinusoideum" EXACT []
synonym: "vas sinusoideum" EXACT OMO:0003011 [Wikipedia:Hepatic_sinusoid]
xref: EHDAA2:0000999
xref: EMAPA:17365
xref: FMA:17543
xref: MA:0000367
xref: NCIT:C32733
xref: SCTID:67435004
xref: TAO:0005091
xref: UMLS:C0227523 {source="ncithesaurus:Hepatic_Sinusoid"}
xref: VHOG:0000708
xref: Wikipedia:Hepatic_sinusoid
xref: ZFA:0005091
is_a: UBERON:0003909 ! sinusoid
is_a: UBERON:0005911 ! endo-epithelium
is_a: UBERON:0015796 ! liver blood vessel
intersection_of: UBERON:0003909 ! sinusoid
intersection_of: part_of UBERON:0002107 ! liver
relationship: connected_to UBERON:0006841 ! central vein of liver
relationship: contributes_to_morphology_of UBERON:0004647 ! liver lobule
relationship: develops_in UBERON:0001113 ! lobe of liver
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0004647 ! liver lobule
relationship: part_of UBERON:0006877 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! vasculature of liver
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "(...) the amphibian liver has characteristics in common with both fish and terrestrial vertebrates. (...) The histological structure of the liver is similar to that in other vertebrates, with hepatocytes arranged in clusters and cords separated by a meshwork of sinusoids and the presence of the traditional triad of portal venule, hepatic arteriole, and bile duct.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000708", ontology="VHOG", source="DOI:10.1053/ax.2000.7133 Crawshaw GJ, Weinkle TK, Clinical and pathological aspects of the amphibian liver. Seminars in Avian and Exotic Pet Medicine (2000)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001282
name: intralobular bile duct
namespace: uberon
def: "The tubules located between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule." [MGI:csmith, MP:0009499]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "canal of Hering" RELATED []
synonym: "canal of Herring" EXACT [FMA:17545]
synonym: "canals of Hering" RELATED OMO:0003004 [Wikipedia:Canals_of_Hering]
synonym: "cholangiole" EXACT [FMA:17545]
synonym: "duct of Herring" RELATED [Wikipedia:Canals_of_Hering]
synonym: "ductus interlobularis bilifer" EXACT OMO:0003011 [FMA:17545, FMA:TA]
synonym: "intrahepatic bile ductule" RELATED [Wikipedia:Canals_of_Hering]
xref: FMA:17545
xref: MA:0002669
xref: NCIT:C32255
xref: SCTID:227002
xref: SCTID:269922006
xref: UMLS:C0227517 {source="ncithesaurus:Canal_of_Hering"}
xref: Wikipedia:Canals_of_Hering
is_a: UBERON:0003704 {source="FMA"} ! intrahepatic bile duct
is_a: UBERON:0014716 ! interlobular duct
relationship: contributes_to_morphology_of UBERON:0004647 ! liver lobule
relationship: has_part CL:0000182 ! hepatocyte
relationship: has_part CL:1000488 ! cholangiocyte
relationship: part_of UBERON:0001172 {source="FMA"} ! hepatic acinus
relationship: part_of UBERON:0004647 {source="FMA"} ! liver lobule
property_value: editor_note "Note that this is part of the intrahepatic bile duct in MA, as this class is more alike the tree in FMA. Note also that SCT has canal of Hering and Entire IBduct as the only sibling terms under 'Structure of intralobular bile duct' (i.e. the CoH is the only part of the entire IBduct)" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001285
name: nephron
namespace: uberon
def: "The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]." [PMID:9268568, Wikipedia:Nephron]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "mature nephron" NARROW [EMAPA:28491]
synonym: "nephroneum" RELATED OMO:0003011 [Wikipedia:Nephron]
synonym: "tubulus renalis" RELATED OMO:0003011 [Wikipedia:Nephron]
xref: BTO:0000924
xref: CALOHA:TS-1312
xref: EMAPA:28491
xref: EMAPA:35592
xref: EV:0100384
xref: FMA:17640
xref: GAID:428
xref: MA:0000375
xref: MESH:D009399
xref: NCIT:C13048
xref: SCTID:361337001
xref: TAO:0002153
xref: UMLS:C0027713 {source="ncithesaurus:Nephron"}
xref: Wikipedia:Nephron
xref: ZFA:0005282
is_a: UBERON:0000064 ! organ part
relationship: contributes_to_morphology_of UBERON:0002113 ! kidney
relationship: develops_from UBERON:0010532 ! primitive nephron
relationship: immediate_transformation_of UBERON:0010532 {source="Bgee:AN"} ! primitive nephron
relationship: part_of UBERON:0007684 {source="FMA"} ! uriniferous tubule
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png" xsd:anyURI
property_value: editor_note "kidney terms require review for cross-vertebrate compatibility and developmental relationships." xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Functional unit of the kidney that filters waste.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002153", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000008 "In the avian kidney, three types of nephron are identified: mammalian-type nephrons with long and short loops of Henle, and reptilian type nephrons (Gambaryan, 1992)" xsd:string {source="GO"}

[Term]
id: UBERON:0001295
name: endometrium
namespace: uberon
def: "The glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy." [MESH:A05.360.319.679.490, MGI:smb, MP:0004896]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "tunica mucosa (endometrium)" EXACT [FMA:17742]
synonym: "tunica mucosa uteri" EXACT OMO:0003011 [Wikipedia:Endometrium]
synonym: "uterine endometrium" EXACT [BTO:0001422]
synonym: "uterine mucosa" RELATED []
synonym: "uterine mucous membrane" RELATED [BTO:0001422]
xref: BTO:0001422
xref: CALOHA:TS-0276
xref: EFO:0000980
xref: EMAPA:29917
xref: EV:0100115
xref: FMA:17742
xref: GAID:377
xref: MA:0000390
xref: MAT:0000319
xref: MESH:D004717
xref: MIAA:0000319
xref: NCIT:C12313
xref: SCTID:278867007
xref: UMLS:C0014180 {source="ncithesaurus:Endometrium"}
xref: VHOG:0001285
xref: Wikipedia:Endometrium
is_a: UBERON:0019042 ! reproductive system mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000995 ! uterus
relationship: contributes_to_morphology_of UBERON:0000995 ! uterus
relationship: only_in_taxon NCBITaxon:40674 ! Mammalia
relationship: part_of UBERON:0000459 {source="FMA"} ! uterine wall
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The mucous membrane lining the uterus. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001285", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/Endometrium"}
property_value: UBPROP:0000003 "The maternal part of the placenta (of eutherian mammals) is the vascularized and glandular uterine lining, or endometrium.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001285", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.144", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "endometrial" xsd:string
property_value: UBPROP:0000008 "Animals that have estrous cycles reabsorb the endometrium if conception does not occur during that cycle. Animals that have menstrual cycles shed the endometrium through menstruation instead" xsd:string
property_value: UBPROP:0000012 "in FMA this is subdivided into basal and outer" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001297
name: serosa of uterus
namespace: uberon
def: "Outer serosa layer of the uterus." [Wikipedia:Perimetrium]
synonym: "perimetrium" EXACT [Wikipedia:Perimetrium]
synonym: "serous coat of uterus" EXACT [Wikipedia:Perimetrium]
synonym: "serous membrane of uterus" EXACT [OBOL:automatic]
synonym: "tunica serosa (perimetrium)" EXACT []
synonym: "tunica serosa uteri" EXACT OMO:0003011 [FMA:17744, FMA:TA]
synonym: "uterine serosa" EXACT []
synonym: "uterus serosa" EXACT []
synonym: "uterus serous membrane" EXACT [OBOL:automatic]
synonym: "visceral peritoneum of uterus" EXACT []
xref: EMAPA:37792 {source="MA:th"}
xref: FMA:17744
xref: MA:0001729
xref: NCIT:C33298
xref: SCTID:253705006
xref: UMLS:C0227824 {source="ncithesaurus:Perimetrium"}
xref: Wikipedia:Perimetrium
is_a: UBERON:0000042 ! serous membrane
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0000995 ! uterus
relationship: part_of UBERON:0000459 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! uterine wall
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg" xsd:anyURI
property_value: editor_note "TODO - check for parallel structure with peritoneum" xsd:string

[Term]
id: UBERON:0001299
name: glans penis
namespace: uberon
def: "The conic expansion of the corpus spongiosum that forms the head of the penis." [MGI:anna, MP:0009102]
subset: pheno_slim
subset: uberon_slim
synonym: "balanus" RELATED [BTO:0003118]
synonym: "coronal sulcus" RELATED INCONSISTENT [Wikipedia:Glans_penis]
synonym: "glans" BROAD [EV:0100108]
xref: BTO:0003118
xref: EMAPA:18988
xref: EV:0100108
xref: FMA:18247
xref: GAID:0000012
xref: MA:0002726
xref: NCIT:C12324
xref: SCTID:263378009
xref: UMLS:C0227948 {source="ncithesaurus:Glans_Penis"}
xref: VHOG:0001475
xref: Wikipedia:Glans_penis
is_a: UBERON:0035651 ! glans
intersection_of: UBERON:0035651 ! glans
intersection_of: part_of UBERON:0000989 ! penis
relationship: contributes_to_morphology_of UBERON:0000989 ! penis
relationship: develops_from UBERON:0013239 ! future glans penis
relationship: immediate_transformation_of UBERON:0013239 {source="Bgee:AN"} ! future glans penis
relationship: part_of UBERON:0000989 ! penis
relationship: sexually_homologous_to UBERON:0006653 ! glans clitoris
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/13/Anteriorglanspenis.jpg" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png" xsd:anyURI

[Term]
id: UBERON:0001301
name: epididymis
namespace: uberon
def: "The elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens." [MGI:pvb, MP:0002631]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
xref: BTO:0000408
xref: CALOHA:TS-0285
xref: EFO:0000982
xref: EMAPA:19290
xref: EV:0100103
xref: FMA:18255
xref: GAID:397
xref: galen:Epididymis
xref: MA:0000397
xref: MAT:0000130
xref: MESH:D004822
xref: MIAA:0000130
xref: NCIT:C12328
xref: SCTID:181432000
xref: UMLS:C0014533 {source="ncithesaurus:Epididymis"}
xref: VHOG:0001265
xref: Wikipedia:Epididymis
is_a: UBERON:0000025 ! tube
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005904 ! duct of male reproductive system
relationship: channel_for CL:0000019 ! sperm
relationship: channels_from UBERON:0006946 ! efferent duct
relationship: channels_into UBERON:0001000 ! vas deferens
relationship: contributes_to_morphology_of UBERON:0004054 ! internal male genitalia
relationship: develops_from UBERON:0003074 {source="Wikipedia"} ! mesonephric duct
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0006947 {source="FMA"} ! male genital duct
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_testis_surface.jpg" xsd:anyURI
property_value: editor_note "Kardong has epididymis in elasmobranch" xsd:string
property_value: UBPROP:0000007 "epididymal" xsd:string
property_value: UBPROP:0000008 "A similar, but probably non-homologous, structure is found in cartilaginous fishes" xsd:string {source="WP"}
property_value: UBPROP:0000010 "Typically divided into three main regions. In reptiles, there is an additional canal between the testis and the head of the epididymis, which receives the various efferent ducts. This is, however, absent in all birds and mammals. The epididymis is covered by a two layered pseudostratified epithelium. The epithelium is separated by a basement membrane from the connective tissue wall which has smooth muscle cells." xsd:string

[Term]
id: UBERON:0001302
name: right uterine tube
namespace: uberon
def: "A fallopian tube that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic]
synonym: "right fallopian tube" EXACT []
synonym: "right oviduct" EXACT []
xref: EMAPA:37369 {source="MA:th"}
xref: FMA:18483
xref: MA:0001717
xref: NCIT:C33475
xref: SCTID:280106006
xref: UMLS:C0227900 {source="ncithesaurus:Right_Fallopian_Tube"}
is_a: UBERON:0003889 ! fallopian tube
intersection_of: UBERON:0003889 ! fallopian tube
intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism
relationship: in_right_side_of UBERON:0000468 ! multicellular organism
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Fallopian_Tube_R.glb" xsd:anyURI
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI
property_value: UBPROP:0000008 "non-functional in monotremes[ISBN:978-0226870137]" xsd:string

[Term]
id: UBERON:0001303
name: left uterine tube
namespace: uberon
def: "A fallopian tube that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic]
synonym: "left fallopian tube" EXACT []
synonym: "left oviduct" EXACT []
xref: EMAPA:37368 {source="MA:th"}
xref: FMA:18484
xref: MA:0001716
xref: NCIT:C32959
xref: SCTID:280107002
xref: UMLS:C0227902 {source="ncithesaurus:Left_Fallopian_Tube"}
is_a: UBERON:0003889 ! fallopian tube
intersection_of: UBERON:0003889 ! fallopian tube
intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Fallopian_Tube_L.glb" xsd:anyURI
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0001310
name: umbilical artery
namespace: uberon
def: "The umbilical artery is a paired artery (with one for each half of the body) that is found in the abdominal and pelvic regions. In the fetus, it extends into the umbilical cord. [WP,unvetted]." [https://github.com/obophenotype/uberon/issues/328, Wikipedia:Umbilical_artery]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "a. umbilicalis" RELATED OMO:0003011 [Wikipedia:Umbilical_artery]
xref: BTO:0000841
xref: CALOHA:TS-1077
xref: EHDAA:1026
xref: EHDAA:410
xref: EMAPA:16331
xref: EMAPA:16372
xref: FMA:18820
xref: GAID:516
xref: MA:0002072
xref: MESH:D014469
xref: NCIT:C33827
xref: RETIRED_EHDAA2:0002106
xref: SCTID:261404000
xref: UMLS:C0041632 {source="ncithesaurus:Umbilical_Artery"}
xref: Wikipedia:Umbilical_artery
is_a: UBERON:0001637 ! artery
is_a: UBERON:0010260 ! umbilical blood vessel
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Gray502.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb" xsd:anyURI
property_value: editor_note "todo - compare with EHDAA2. Check embryonic vs extraembryonic, developmental relationships" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/328" xsd:anyURI

[Term]
id: UBERON:0001312
name: superior vesical artery
namespace: uberon
def: "An artery that supplies blood to the upper urinary bladder." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: uberon_slim
synonym: "arteria vesicali superior" EXACT OMO:0003011 [Wikipedia:Superior_vesical_artery]
synonym: "arteria vesicalis superior" EXACT OMO:0003011 [Wikipedia:Superior_vesical_artery]
synonym: "arteriae vesicales superiores" RELATED OMO:0003011 [Wikipedia:Superior_vesical_artery]
xref: EMAPA:37123 {source="MA:th"}
xref: FMA:18839
xref: MA:0002080
xref: NCIT:C52686
xref: SCTID:113268007
xref: UMLS:C0226376 {source="ncithesaurus:Superior_Vesical_Artery"}
xref: Wikipedia:Superior_vesical_artery
is_a: UBERON:0003468 ! ureteric segment of renal artery
is_a: UBERON:0009027 ! vesical artery
intersection_of: UBERON:0009027 ! vesical artery
intersection_of: supplies UBERON:0000056 ! ureter
relationship: connecting_branch_of UBERON:0001310 ! umbilical artery
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/0/02/Internal_iliac_branches.PNG" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000011 "The first part of the superior vesical artery represents the terminal section of the previous portion of the umbilical artery (fetal hypogastric artery)[WP]" xsd:string

[Term]
id: UBERON:0001317
name: internal iliac vein
namespace: uberon
def: "A vein that begins near the upper part of the greater sciatic foramen, passes upward behind and slightly medial to the hypogastric artery and, at the brim of the pelvis, joins with the external iliac to form the common iliac vein. [WP,unvetted]." [Wikipedia:Internal_iliac_vein]
subset: human_reference_atlas
subset: uberon_slim
synonym: "hypogastric vein" RELATED [MA:0002139, Wikipedia:Internal_iliac_vein]
synonym: "v. hypogastrica" RELATED OMO:0003011 [Wikipedia:Internal_iliac_vein]
synonym: "v. iliaca interna" RELATED OMO:0003011 [Wikipedia:Internal_iliac_vein]
xref: EHDAA2:0000874
xref: EMAPA:37148 {source="MA:th"}
xref: FMA:18884
xref: galen:InternalIliacVein
xref: MA:0002139
xref: MA:0002145
xref: NCIT:C32847
xref: SCTID:181399007
xref: UMLS:C0226764 {source="ncithesaurus:Internal_Iliac_Vein"}
xref: VHOG:0000749
xref: Wikipedia:Internal_iliac_vein
is_a: UBERON:0005610 {source="MA"} ! iliac vein
relationship: connected_to UBERON:0001139 ! common iliac vein
relationship: drains UBERON:0005179 ! pelvic region element
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/cb/Internaliliacv.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001325
name: muscle of pelvis
namespace: uberon
def: "Muscle (organ) which is a part of the pelvis. Examples: levator ani,." [FMA:19086]
subset: pheno_slim
subset: uberon_slim
synonym: "muscle organ of pelvis" EXACT [OBOL:automatic]
synonym: "pelvic muscle" EXACT [FMA:19086]
synonym: "pelvis muscle" EXACT []
synonym: "pelvis muscle organ" EXACT [OBOL:automatic]
xref: EMAPA:18184
xref: EMAPA:37481 {source="MA:th"}
xref: FMA:19086
xref: MA:0000534
is_a: UBERON:0003833 {source="MA"} ! abdominal segment muscle
is_a: UBERON:0005179 ! pelvic region element
intersection_of: UBERON:0014892 {source="FMAdef"} ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0002355 {source="FMAdef"} ! pelvic region of trunk

[Term]
id: UBERON:0001330
name: pampiniform plexus
namespace: uberon
def: "The pampiniform plexus is a network of many small veins found in the male spermatic cord. It is formed by the union of multiple spermatic veins from the back of the testis and tributaries from the epididymis. The veins of the plexus ascend along the cord in front of the ductus deferens. Below the subcutaneous inguinal ring they unite to form three or four veins, which pass along the inguinal canal, and, entering the abdomen through the abdominal inguinal ring, coalesce to form two veins. These again unite to form a single vein, the testicular vein, which opens on the right side into the inferior vena cava, at an acute angle, and on the left side into the left renal vein, at a right angle. The pampinoform plexus forms the chief mass of the cord. In addition to its function in venous return from the testes, the pampiniform plexus also plays a role in the temperature regulation of the testes. It acts as a heat exchanger, cooling blood in adjacent arteries. An abnormal enlargement of the pampiniform plexus is a medical condition called varicocele. [WP,unvetted]." [Wikipedia:Pampiniform_venous_plexus]
subset: human_reference_atlas
subset: uberon_slim
synonym: "pampiniform venous plexus" EXACT []
synonym: "plexus of veins of fascia of prostate" EXACT []
synonym: "plexus venosus pampiniformis" EXACT OMO:0003011 [FMA:19607, FMA:TA]
synonym: "venous plexus of fascia of prostate" EXACT []
synonym: "venous plexus of fascia of prostate gland" EXACT []
xref: EMAPA:37385 {source="MA:th"}
xref: FMA:19607
xref: MA:0001866
xref: SCTID:279661001
xref: Wikipedia:Pampiniform_venous_plexus
is_a: UBERON:0001593 ! venous plexus
relationship: connected_to UBERON:0000442 ! right testicular vein
relationship: located_in UBERON:0005352 ! spermatic cord
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/af/Gray1147.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001331
name: skin of penis
namespace: uberon
def: "A zone of skin that is part of a penis [Automatically generated definition]." [OBOL:automatic]
synonym: "penile skin" EXACT [FMA:19638]
synonym: "penis skin" EXACT []
synonym: "penis zone of skin" EXACT [OBOL:automatic]
synonym: "zone of skin of penis" EXACT [OBOL:automatic]
xref: EMAPA:35675
xref: FMA:19638
xref: MA:0002727
xref: SCTID:35900000
is_a: UBERON:0000014 ! zone of skin
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0000989 ! penis
relationship: continuous_with UBERON:0001085 ! skin of trunk
relationship: part_of UBERON:0000989 ! penis

[Term]
id: UBERON:0001333
name: male urethra
namespace: uberon
def: "A urethra that is part of a male reproductive system." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: uberon_slim
xref: BTO:0004089
xref: EMAPA:18692
xref: FMA:19668
xref: MA:0002640
xref: NCIT:C33050
xref: SCTID:264085007
xref: UMLS:C0458452 {source="ncithesaurus:Male_Urethra"}
xref: Wikipedia:Male_urethra
is_a: UBERON:0000057 ! urethra
intersection_of: UBERON:0000057 ! urethra
intersection_of: part_of UBERON:0003101 ! male organism
relationship: part_of UBERON:0003101 ! male organism
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Urethra.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI

[Term]
id: UBERON:0001334
name: female urethra
namespace: uberon
def: "A urethra that is part of a female reproductive system." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: uberon_slim
synonym: "urethra feminina" RELATED [BTO:0004088]
synonym: "urethra muliebris" RELATED [BTO:0004088]
xref: BTO:0004088
xref: EMAPA:28747
xref: FMA:19669
xref: MA:0002637
xref: NCIT:C32591
xref: SCTID:264469008
xref: UMLS:C0458485 {source="ncithesaurus:Female_Urethra"}
xref: Wikipedia:Female_urethra
is_a: UBERON:0000057 ! urethra
intersection_of: UBERON:0000057 ! urethra
intersection_of: part_of UBERON:0003100 ! female organism
relationship: part_of UBERON:0003100 ! female organism
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI

[Term]
id: UBERON:0001338
name: urethral gland
namespace: uberon
def: "Any of the numerous small mucous-secreting glands located in the wall of the male or female urethra that help protect the epithelium from the corrosive urine." [MP:anna]
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "gland of urethra" EXACT [OBOL:automatic]
synonym: "urethra gland" EXACT []
synonym: "urethra gland (male or female)" EXACT []
synonym: "urethral mucuous gland" EXACT []
xref: EMAPA:37784 {source="MA:th"}
xref: FMA:19683
xref: MA:0001688
xref: SCTID:279477005
is_a: UBERON:0000414 {source="MP"} ! mucous gland
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0000057 ! urethra
relationship: contributes_to_morphology_of UBERON:0000057 ! urethra
relationship: only_in_taxon NCBITaxon:40674 ! Mammalia
relationship: part_of UBERON:0000057 ! urethra
property_value: UBPROP:0000012 "NCIT:C12339 paraurethral gland belongs here" xsd:string {external_ontology="NCIT"}

[Term]
id: UBERON:0001343
name: seminiferous tubule of testis
namespace: uberon
def: "The tubules in the testes where spermatogenesis occurs." [https://github.com/obophenotype/uberon/issues/1381, ISBN:0-683-40008-8, MGI:csmith, MP:0002216]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "seminiferous cord" EXACT [EMAPA:18685]
synonym: "seminiferous tubule" EXACT []
synonym: "testis - seminiferous tubule" EXACT []
synonym: "tubuli seminiferi" EXACT []
synonym: "tubuli seminiferi" RELATED OMO:0003011 [Wikipedia:Seminiferous_tubule]
xref: AAO:0010399
xref: BTO:0001235
xref: CALOHA:TS-1239
xref: EFO:0001404
xref: EMAPA:18685
xref: EMAPA:31476
xref: EV:0100380
xref: FMA:19825
xref: GAID:400
xref: MA:0000412
xref: MAT:0000503
xref: MESH:D012671
xref: NCIT:C13047
xref: NCIT:C34293
xref: SCTID:279614002
xref: UMLS:C0036630 {source="ncithesaurus:Seminiferous_Tubule"}
xref: UMLS:C1519236 {source="ncithesaurus:Seminiferous_Cord"}
xref: VHOG:0001363
xref: Wikipedia:Seminiferous_tubule
xref: XAO:0003088
is_a: UBERON:0000025 ! tube
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005904 ! duct of male reproductive system
relationship: channel_for CL:0000019 ! sperm
relationship: channels_into UBERON:0003959 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! rete testis
relationship: contains_process GO:0007283 ! spermatogenesis
relationship: develops_from UBERON:0005297 {source="Wikipedia"} ! testis sex cord
relationship: part_of UBERON:0000473 ! testis
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/49/Seminiferous_tubule_and_sperm_low_mag.jpg" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6a/Gray1145.png" xsd:anyURI
property_value: UBPROP:0000001 "Any of the coiled tubules located in the testes in which spermatozoa are produced.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010399", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "One of two or three twisted curved tubules in each lobule of the testis in which spermatogenesis occurs. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001363", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/SEMINIFEROUS+TUBULE"}
property_value: UBPROP:0000003 "Frogs among amphibians and the amniotes have males with testes that are composed of seminiferous tubules, which differ from ampullae in being long, highly convoluted ductules.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001363", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.688 and Figure 21-28", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001353
name: anal region
namespace: uberon
def: "The anus and surrounding regions. Encompasses both internal and external regions, where present." [https://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "posterior" RELATED []
synonym: "posterior end of organism" RELATED []
xref: EFO:0000847
xref: EHDAA2:0000122
xref: EHDAA:2931
xref: EMAPA:16831
xref: MA:0000329
xref: MAT:0000042
xref: MIAA:0000042
xref: NCIT:C32069
xref: SCTID:362680001
xref: UMLS:C0230120 {source="ncithesaurus:Anal_Region"}
xref: VHOG:0000395
xref: WBbt:0006919
is_a: UBERON:0000475 ! organism subdivision
relationship: has_developmental_contribution_from UBERON:0000931 {evidence="cjm"} ! proctodeum
relationship: overlaps UBERON:0006866 ! terminal part of digestive tract
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png" xsd:anyURI
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/507" xsd:anyURI
property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000395", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001366
name: parietal peritoneum
namespace: uberon
alt_id: UBERON:0004459
def: "The outer layer of peritoneum that is attached to the abdominal and pelvic walls." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Peritoneum#Types]
subset: uberon_slim
subset: vertebrate_core
synonym: "parietal serous membrane of peritoneum" EXACT [UBERON:cjm]
synonym: "peritoneal cavity lining" RELATED []
xref: AAO:0010816
xref: EMAPA:16591
xref: FMA:21451
xref: SCTID:362700006
xref: TAO:0005131
xref: VHOG:0001527
xref: Wikipedia:Parietal_peritoneum
xref: ZFA:0005131
is_a: UBERON:0022351 ! parietal serous membrane
intersection_of: UBERON:0022351 ! parietal serous membrane
intersection_of: part_of UBERON:0002358 ! peritoneum
relationship: attaches_to UBERON:0003697 ! abdominal wall
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0002358 ! peritoneum
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png" xsd:anyURI
property_value: UBPROP:0000001 "Peritoneum attached to the abdominal wall.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010816", ontology="AAO", source="AAO:JMG"}

[Term]
id: UBERON:0001415
name: skin of pelvis
namespace: uberon
def: "A zone of skin that is part of a pelvis [Automatically generated definition]." [OBOL:automatic]
synonym: "pelvic skin" EXACT []
synonym: "pelvis skin" EXACT []
synonym: "pelvis zone of skin" EXACT [OBOL:automatic]
synonym: "zone of skin of pelvis" EXACT [OBOL:automatic]
xref: EMAPA:37282 {source="MA:th"}
xref: FMA:22984
xref: MA:0000546
xref: SCTID:181517009
is_a: UBERON:0003836 ! abdominal segment skin
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0002355 ! pelvic region of trunk

[Term]
id: UBERON:0001416
name: skin of abdomen
namespace: uberon
def: "A zone of skin that is part of an abdomen [Automatically generated definition]." [OBOL:automatic]
subset: efo_slim
subset: pheno_slim
synonym: "abdomen skin" EXACT []
synonym: "abdomen zone of skin" EXACT [OBOL:automatic]
synonym: "abdominal skin" EXACT []
synonym: "skin of abdomen proper" EXACT [FMA:22988]
synonym: "zone of skin of abdomen" EXACT [OBOL:automatic]
xref: EFO:0000214
xref: FMA:22988
xref: FMA:23000
xref: MA:0000523
xref: NCIT:C52758
xref: SCTID:361707007
xref: UMLS:C0222166 {source="ncithesaurus:Abdominal_Skin"}
is_a: UBERON:0003836 ! abdominal segment skin
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0000916 ! abdomen

[Term]
id: UBERON:0001417
name: skin of neck
namespace: uberon
def: "A zone of skin that is part of a neck [Automatically generated definition]." [OBOL:automatic]
synonym: "neck (volume) zone of skin" EXACT [OBOL:automatic]
synonym: "neck skin" EXACT []
synonym: "neck zone of skin" EXACT [OBOL:automatic]
synonym: "zone of skin of neck" EXACT [OBOL:automatic]
synonym: "zone of skin of neck (volume)" EXACT [OBOL:automatic]
xref: EMAPA:37277 {source="MA:th"}
xref: FMA:23021
xref: FMA:23022
xref: MA:0000590
xref: NCIT:C52756
xref: SCTID:361705004
xref: UMLS:C0205030 {source="ncithesaurus:Neck_Skin"}
is_a: UBERON:0000014 ! zone of skin
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0000974 ! neck
relationship: part_of UBERON:0000974 ! neck

[Term]
id: UBERON:0001418
name: skin of thorax
namespace: uberon
def: "A zone of skin that is part of a thorax [Automatically generated definition]." [OBOL:automatic]
synonym: "thoracic skin" EXACT []
synonym: "thorax skin" EXACT []
synonym: "thorax zone of skin" EXACT [OBOL:automatic]
synonym: "upper body skin" RELATED []
synonym: "zone of skin of thorax" EXACT [OBOL:automatic]
xref: EMAPA:37765 {source="MA:th"}
xref: FMA:23028
xref: FMA:23029
xref: MA:0000564
xref: SCTID:281723000
is_a: UBERON:0001085 ! skin of trunk
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0000915 ! thoracic segment of trunk

[Term]
id: UBERON:0001421
name: pectoral girdle region
namespace: uberon
def: "An organism subdivision that includes the pectoral girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions." [FMA:23217, https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cingulum membri superioris" EXACT OMO:0003011 [FMA:23217, FMA:TA]
synonym: "cingulum membri superioris" NARROW [FMA:TA]
synonym: "girdle - pectoral" EXACT []
synonym: "pectoral girdle" RELATED []
synonym: "pectoral region" RELATED []
synonym: "shoulder girdle" NARROW [FMA:23217]
synonym: "upper limb girdle" NARROW [FMA:23217]
xref: EMAPA:37856 {source="MA:th"}
xref: FMA:23217
xref: galen:ShoulderGirdle
xref: SCTID:229759004
xref: VSAO:0000305
is_a: UBERON:0007823 ! appendage girdle region
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0007823 ! appendage girdle region
intersection_of: part_of UBERON:0010708 ! pectoral complex
disjoint_from: UBERON:0007831 ! pectoral girdle skeleton
relationship: has_skeleton UBERON:0007831 ! pectoral girdle skeleton
relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism
relationship: part_of UBERON:0010708 ! pectoral complex
property_value: curator_notes "this class describes the organism subdivision, NOT the skeleton within. See also: skeleton of pectoral girdle (UBERON:0007831)." xsd:string
property_value: RO:0002171 UBERON:0001271
property_value: UBPROP:0000001 "An organism subdivision that includes the pectoral girdle skeleton. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). There is only one instance of the pectoral girdle region per organism.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000305", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"}
property_value: UBPROP:0000005 "Note that this class describes the central subdivision of the pectoral girdle complex, NOT the skeleton within.[VSAO]" xsd:string {date_retrieved="2012-09-06", external_class="VSAO:0000305", ontology="VSAO", source="Curator"}

[Term]
id: UBERON:0001434
name: skeletal system
namespace: uberon
def: "Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000027]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "set of all bones and joints" NARROW SENSU []
synonym: "skeleton system" EXACT []
synonym: "Skelettsystem" RELATED [BTO:0001486]
xref: AAO:0000566
xref: BTO:0001486
xref: CALOHA:TS-1320
xref: EFO:0000806
xref: EHDAA2:0003168
xref: EMAPA:35773
xref: FMA:23881
xref: MA:0000018
xref: NCIT:C12788
xref: TAO:0000434
xref: UMLS:C0037253 {source="ncithesaurus:Skeletal_System"}
xref: VHOG:0001254
xref: VSAO:0000027
xref: XAO:0003060
xref: ZFA:0000434
is_a: UBERON:0011216 ! organ system subdivision
intersection_of: UBERON:0011216 ! organ system subdivision
intersection_of: has_part UBERON:0004288 ! skeleton
intersection_of: has_part UBERON:0004770 ! articular system
disjoint_from: UBERON:0001474 ! bone element
disjoint_from: UBERON:0002204 ! musculoskeletal system
disjoint_from: UBERON:0002294 ! biliary system
disjoint_from: UBERON:0002330 ! exocrine system
disjoint_from: UBERON:0002390 ! hematopoietic system
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: has_part UBERON:0004288 ! skeleton
relationship: has_part UBERON:0004770 ! articular system
relationship: part_of UBERON:0002204 ! musculoskeletal system
property_value: RO:0002171 UBERON:0001016
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/The-skeletal-system" xsd:anyURI
property_value: UBPROP:0000001 "Anatomical system consisting of multiple elements and tissues that provides physical support.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000434", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000001 "Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000027", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"}
property_value: UBPROP:0000001 "System that provides physical support to the organism.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000566", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000003 "By taking a holistic approach, integration of the evidence from molecular and developmental features of model organisms, the phylogenetic distribution in the 'new animal phylogeny' and the earliest fossilized remains of mineralized animal skeletons suggests independent origins of the skeleton at the phylum level.[debated][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001254", ontology="VHOG", source="DOI:10.1159/000324245 Donoghue PCJ, Sansom IJ, Origin and early evolution of vertebrate skeletonization. Microscopy research and technique (2002)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "skeletal" xsd:string
property_value: UBPROP:0000012 "GO defines skeletal system very generically: The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton) GO:0001501; however, all annotations are to vertebrates" xsd:string {external_ontology="GO"}

[Term]
id: UBERON:0001444
name: subdivision of head
namespace: uberon
subset: non_informative
synonym: "head region" RELATED []
synonym: "head subdivision" EXACT []
synonym: "region of head" RELATED []
xref: FMA:24218
xref: SCTID:123852005
xref: XAO:0000040
is_a: UBERON:0000475 ! organism subdivision
relationship: part_of UBERON:0000033 ! head

[Term]
id: UBERON:0001456
name: face
namespace: uberon
def: "A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc)." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: uberon_slim
synonym: "facia/facies" RELATED OMO:0003011 [Wikipedia:Face]
synonym: "visage" RELATED [BTO:0003369]
xref: BTO:0003369
xref: CALOHA:TS-2216
xref: EMAPA:32763
xref: FMA:24728
xref: GAID:64
xref: galen:Face
xref: HAO:0000316
xref: MA:0002473
xref: MESH:D005145
xref: NCIT:C13071
xref: SCTID:302549007
xref: UMLS:C0015450 {source="ncithesaurus:Face"}
xref: Wikipedia:Face
is_a: UBERON:0001444 ! subdivision of head
relationship: contributes_to_morphology_of UBERON:0000033 ! head
relationship: has_part UBERON:0000018 {gci_filler="NCBITaxon:50557", gci_relation="part_of"} ! compound eye
relationship: has_part UBERON:0000165 ! mouth
relationship: has_part UBERON:0011156 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! facial skeleton
relationship: has_skeleton UBERON:0011156 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! facial skeleton
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/55/Mona_Lisa_headcrop.jpg" xsd:anyURI
property_value: UBPROP:0000001 "Subdivision of head which consists of the viscerocranium and all layers superficial to it. Examples: There is only one face." xsd:string {source="FMA:24728"}
property_value: UBPROP:0000001 "The area that extends from the median ocellus to the oral foramen[HAO]." xsd:string {source="HAO:0000316", source="http://api.hymao.org/api/ref/67791", taxon="NCBITaxon:7399"}
property_value: UBPROP:0000007 "facial" xsd:string
property_value: UBPROP:0000011 "The face develops from outward growth of tissue located rostral to the cranium & pharynx. The lower jaw and most of the upper jaw are formed by growth of the first pharyngeal (branchial) arch. The upper incisor region and the nose and forehead (frontal region) are formed from tissue located rostral to the neural tube (frontonasal prominence)" xsd:string {source="vanat.cvm.umn.edu/TFFlectPDFs/LectFaceDevelop.pdf"}

[Term]
id: UBERON:0001458
name: skin of lip
namespace: uberon
def: "A zone of skin that is part of a lip [Automatically generated definition]." [OBOL:automatic]
synonym: "lip skin" EXACT []
synonym: "lip zone of skin" EXACT [OBOL:automatic]
synonym: "skin of lips" RELATED OMO:0003004 []
synonym: "zone of skin of lip" EXACT [OBOL:automatic]
xref: EMAPA:37643 {source="MA:th"}
xref: FMA:24764
xref: MA:0001579
xref: NCIT:C12291
xref: SCTID:244092005
xref: UMLS:C0222101 {source="ncithesaurus:Skin_of_the_Lip"}
is_a: UBERON:0000014 ! zone of skin
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0001833 ! lip
relationship: part_of UBERON:0001833 ! lip

[Term]
id: UBERON:0001474
name: bone element
namespace: uberon
def: "Skeletal element that is composed of bone tissue." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/277, PSPUB:0000170, VSAO:0000057]
subset: efo_slim
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "bone" RELATED [AEO:0000082, BTO:0000140, MA:0001459, VHOG:0001190]
synonym: "bone organ" EXACT [FMA:5018]
synonym: "bones" RELATED OMO:0003004 [ZFA:0001514]
xref: AAO:0000047
xref: AEO:0000082
xref: BTO:0000140
xref: CALOHA:TS-0088
xref: EFO:0000298
xref: EHDAA2:0003082
xref: EMAPA:32782
xref: ENVO:00002039
xref: EV:0100140
xref: FMA:30317
xref: FMA:5018
xref: GAID:92
xref: galen:Bone
xref: MA:0001459
xref: MAT:0000299
xref: MIAA:0000299
xref: NCIT:C12366
xref: SCTID:90780006
xref: TAO:0001514
xref: UMLS:C0262950 {source="ncithesaurus:Bone"}
xref: VHOG:0001190
xref: VSAO:0000057
xref: Wikipedia:Bone
xref: XAO:0000169
xref: ZFA:0001514
is_a: UBERON:0004765 ! skeletal element
intersection_of: UBERON:0004765 ! skeletal element
intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue
disjoint_from: UBERON:0001630 ! muscle organ
disjoint_from: UBERON:0005090 ! muscle structure
relationship: composed_primarily_of UBERON:0002481 {source="VSAO-modified"} ! bone tissue
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
property_value: RO:0002171 UBERON:0001015
property_value: RO:0002171 UBERON:0001630
property_value: RO:0002171 UBERON:0002385
property_value: UBPROP:0000001 "Also called osseous tissue, (Latin: os). Is a type of hard endoskeletal connective tissue found in many vertebrate animals. Bone is the main tissue of body organs that support body structures, protect internal organs, (in conjunction with muscles) facilitate movement; and are involved with cell formation, calcium metabolism, and mineral storage.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000047", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000001 "Portion of tissue which is calcified connective tissue making up the structural elements of the skeletal system.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001514", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Skeletal element that is composed of bone tissue.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000057", ontology="VSAO", source="PSPUB:0000170"}
property_value: UBPROP:0000002 "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000047", ontology="AAO"}
property_value: UBPROP:0000003 "The 'new animal phylogeny' reveals that many of the groups known to biomineralize sit among close relatives that do not, and it favours an interpretation of convergent or parallel evolution for biomineralization in animals. (...) Whether this 'biomineralization toolkit'of genes reflects a parallel co-option of a common suite of genes or the inheritance of a skeletogenic gene regulatory network from a biomineralizing common ancestor remains an open debate.[debated][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001190", ontology="VHOG", source="DOI:10.1159/000324245 Murdock DJ, Donoghue PC, Evolutionary Origins of Animal Skeletal Biomineralization. Cells Tissues Organs (2011)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001484
name: articular capsule
namespace: uberon
def: "An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]." [Wikipedia:Articular_capsule]
subset: organ_slim
subset: uberon_slim
synonym: "capsula articularis" EXACT OMO:0003011 [FMA:34836, FMA:TA]
synonym: "capsulae articulares" RELATED OMO:0003011 [Wikipedia:Articular_capsule]
synonym: "fibrous capsule of joint" EXACT []
synonym: "joint capsule" EXACT []
synonym: "joint fibrous capsule" EXACT []
xref: EMAPA:37621 {source="MA:th"}
xref: FMA:34836
xref: GAID:263
xref: galen:JointCapsule
xref: MA:0001519
xref: MESH:D017746
xref: NCIT:C32259
xref: NCIT:C84388
xref: SCTID:182238002
xref: UMLS:C0206207 {source="ncithesaurus:Joint_Capsule"}
xref: Wikipedia:Articular_capsule
is_a: UBERON:0000094 ! membrane organ
intersection_of: UBERON:0000094 ! membrane organ
intersection_of: has_part UBERON:0007616 ! layer of synovial tissue
intersection_of: surrounds UBERON:0002217 ! synovial joint
relationship: has_part UBERON:0007616 ! layer of synovial tissue
relationship: surrounds UBERON:0002217 ! synovial joint
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/19/Joint.png" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4a/Gray299.png" xsd:anyURI
property_value: UBPROP:0000012 "check ncita" xsd:string {external_ontology="ncit"}

[Term]
id: UBERON:0001496
name: ascending aorta
namespace: uberon
def: "The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia]." [GO:0035905, Wikipedia:Ascending_aorta]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "aorta ascendens" RELATED OMO:0003011 [Wikipedia:Ascending_aorta]
synonym: "ascending thoracic aorta" EXACT [EMAPA:17014]
synonym: "pars ascendens aortae" EXACT []
synonym: "pars ascendens aortae" RELATED OMO:0003011 [Wikipedia:Ascending_aorta]
xref: EHDAA2:0000147
xref: EHDAA:9828
xref: EMAPA:17014
xref: FMA:3736
xref: MA:0002570
xref: NCIT:C32150
xref: SCTID:181299009
xref: UMLS:C0003956 {source="ncithesaurus:Ascending_Aorta"}
xref: Wikipedia:Ascending_aorta
is_a: UBERON:0001515 ! thoracic aorta
relationship: contributes_to_morphology_of UBERON:0001515 ! thoracic aorta
relationship: develops_from UBERON:0005338 {source="EHDAA2"} ! outflow tract aortic component
relationship: has_developmental_contribution_from UBERON:0002061 ! truncus arteriosus
relationship: has_developmental_contribution_from UBERON:0005432 ! aortic sac
relationship: part_of UBERON:0001515 ! thoracic aorta
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001497
name: muscle of pelvic girdle
namespace: uberon
alt_id: UBERON:0003271
def: "Any muscle organ that is part of a pelvic girdle [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "girdle-pelvic muscle organ" EXACT [OBOL:automatic]
synonym: "muscle organ of girdle-pelvic" EXACT [OBOL:automatic]
synonym: "muscle organ of pelvic girdle" EXACT [OBOL:automatic]
synonym: "muscle organ of pelvic girdle bone" EXACT [OBOL:automatic]
synonym: "pelvic girdle muscle" EXACT []
synonym: "pelvic girdle muscle organ" EXACT [OBOL:automatic]
synonym: "pelvic girdle skeletal muscle" EXACT [EMAPA:18185]
xref: EHDAA:8326
xref: EMAPA:18184
xref: EMAPA:18185
xref: FMA:37367
xref: MA:0000537
xref: RETIRED_EHDAA2:0001430
is_a: UBERON:0001325 ! muscle of pelvis
is_a: UBERON:0010890 ! pelvic complex muscle
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0001271 ! pelvic girdle region
relationship: part_of UBERON:0004470 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! musculature of pelvic girdle
property_value: UBPROP:0000012 "Note that in MA, this is a subclass of pelvis muscle; in FMA this is a hindlimb muscle, but recall in FMA hindlimb includes the girdle." xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001508
name: arch of aorta
namespace: uberon
def: "The convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery." [ISBN:0-683-40008-8, MP:0004113]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "aortic arch" RELATED [FMA:3768]
synonym: "arcus aortae" EXACT OMO:0003011 [FMA:3768, FMA:TA]
synonym: "thoracic aorta" RELATED [GAID:471]
xref: BTO:0000157
xref: EFO:0002526
xref: EHDAA2:0000132
xref: EMAPA:17613
xref: FMA:3768
xref: GAID:471
xref: MA:0000475
xref: SCTID:181300001
xref: VHOG:0001196
xref: Wikipedia:Arch_of_aorta
is_a: UBERON:0001515 ! thoracic aorta
relationship: connected_to UBERON:0001496 ! ascending aorta
relationship: contributes_to_morphology_of UBERON:0001515 ! thoracic aorta
relationship: develops_from UBERON:0003121 {notes="left arch 4 in human", source="embryology.ch"} ! pharyngeal arch artery 4
relationship: has_developmental_contribution_from UBERON:0005432 ! aortic sac
relationship: has_developmental_contribution_from UBERON:0005613 ! left dorsal aorta
relationship: part_of UBERON:0001515 ! thoracic aorta
property_value: curator_notes "Do not confuse with aortic arch" xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The curving portion between the ascending aorta and the descending aorta, giving rise to the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001196", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/arch+of+aorta"}
property_value: UBPROP:0000003 "The double systemic arch arches (left and right) present in amphibians and reptiles become reduced to a single systemic arch - the right in birds, the left in mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001196", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.460 and p.461 Figure 12.20", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "birds have right aortic arch, mammals left." xsd:string

[Term]
id: UBERON:0001514
name: descending aorta
namespace: uberon
def: "The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries[GO]. The descending aorta is part of the aorta, the largest artery in the body. The descending aorta is the part of the aorta beginning at the aortic arch that runs down through the chest and abdomen. The descending aorta is divided into two portions, the thoracic and abdominal, in correspondence with the two great cavities of the trunk in which it is situated. Within the abdomen, the descending aorta branches into the two common iliac arteries which serve the legs. [WP,unvetted]." [GO:0035906, Wikipedia:Descending_aorta]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "aorta descendens" RELATED OMO:0003011 [Wikipedia:Descending_aorta]
synonym: "pars descendens aortae" EXACT [FMA:3784]
synonym: "pars descendens aortae" RELATED OMO:0003011 [Wikipedia:Descending_aorta]
xref: EMAPA:18606
xref: FMA:3784
xref: MA:0002571
xref: NCIT:C32455
xref: SCTID:261399002
xref: UMLS:C0011666 {source="ncithesaurus:Descending_Aorta"}
xref: Wikipedia:Descending_aorta
is_a: UBERON:0005800 {source="FMA"} ! section of aorta
relationship: connected_to UBERON:0001508 ! arch of aorta
relationship: develops_from UBERON:0005805 {source="Wikipedia"} ! dorsal aorta
relationship: has_developmental_contribution_from UBERON:0005613 ! left dorsal aorta
relationship: has_developmental_contribution_from UBERON:0005622 ! right dorsal aorta
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000011 "results from fusion of left and right dorsal aortae" xsd:string

[Term]
id: UBERON:0001515
name: thoracic aorta
namespace: uberon
def: "The part of the aorta that extends from the origin at the heart to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest." [http://www.medterms.com, MP:0010468]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "aorta thoracalis" RELATED OMO:0003011 [Wikipedia:Thoracic_aorta]
synonym: "aorta thoracica" EXACT OMO:0003011 [FMA:3786, FMA:TA]
synonym: "pars thoracica aortae" RELATED OMO:0003011 [Wikipedia:Thoracic_aorta]
synonym: "thoracic part of aorta" EXACT []
xref: BTO:0000157
xref: EFO:0002525
xref: EMAPA:18603
xref: FMA:3786
xref: GAID:471
xref: galen:ThoracicAorta
xref: MA:0002569
xref: MESH:D001013
xref: NCIT:C33766
xref: SCTID:302510009
xref: UMLS:C1522460 {source="ncithesaurus:Thoracic_Aorta"}
xref: Wikipedia:Thoracic_aorta
is_a: UBERON:0005800 {source="FMA"} ! section of aorta
intersection_of: UBERON:0005800 ! section of aorta
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: contributes_to_morphology_of UBERON:0000947 ! aorta
relationship: part_of UBERON:0000915 ! thoracic segment of trunk
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/75/Gray530.png" xsd:anyURI

[Term]
id: UBERON:0001516
name: abdominal aorta
namespace: uberon
def: "Abdominal part of aorta: the distal part of the descending aorta, which is the continuation of the thoracic part and gives rise to the inferior phrenic, lumbar, median sacral, superior and inferior mesenteric, middle suprarenal, renal, and testicular or ovarian arteries, and celiac trunk[BTO]. The abdominal aorta is the largest artery in the abdominal cavity. As part of the aorta, it is a direct continuation of descending aorta(of the thorax). [WP,unvetted]." [BTO:0002976, Wikipedia:Abdominal_aorta]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "abdominal part of aorta" EXACT [FMA:3789]
synonym: "abdominal part of aorta" RELATED [BTO:0002976]
synonym: "aorta abdominalis" RELATED OMO:0003011 [BTO:0002976, Wikipedia:Abdominal_aorta]
synonym: "descending abdominal aorta" EXACT [FMA:3789]
synonym: "pars abdominalis aortae" EXACT [FMA:3789]
synonym: "pars abdominalis aortae" RELATED OMO:0003011 [BTO:0002976, Wikipedia:Abdominal_aorta]
xref: BTO:0002976
xref: EFO:0002524
xref: EMAPA:17856
xref: FMA:3789
xref: GAID:470
xref: galen:AbdominalAorta
xref: MA:0000474
xref: MESH:D001012
xref: NCIT:C32038
xref: SCTID:244231007
xref: UMLS:C0003484 {source="ncithesaurus:Abdominal_Aorta"}
xref: Wikipedia:Abdominal_aorta
is_a: UBERON:0005800 ! section of aorta
relationship: connected_to UBERON:0002345 ! descending thoracic aorta
relationship: contributes_to_morphology_of UBERON:0001514 ! descending aorta
relationship: overlaps UBERON:0000916 ! abdomen
relationship: part_of UBERON:0001514 {source="FMA"} ! descending aorta
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png" xsd:anyURI
property_value: editor_note "Many of the branches of the abdominal aorta in mammals may be branches of the dorsal aorta in other vertebrates" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001529
name: brachiocephalic artery
namespace: uberon
def: "The short first aortic arch branch and divides into the right subclavian artery and the right common carotid artery." [MGI:csmith, MP:0010663]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "brachiocephalic trunk" EXACT [MA:0001922]
synonym: "innominate" BROAD [Wikipedia:Brachiocephalic_artery]
synonym: "innominate artery" EXACT [Wikipedia:Brachiocephalic_artery]
synonym: "truncus brachiocephalicus" EXACT OMO:0003011 [FMA:3932, FMA:TA]
synonym: "truncus brachiocephalicus" RELATED OMO:0003011 [Wikipedia:Brachiocephalic_artery]
xref: EFO:0002550
xref: EHDAA2:0000835
xref: EMAPA:17615
xref: FMA:3932
xref: GAID:476
xref: galen:BrachioCephalicArtery
xref: MA:0001922
xref: MESH:D016122
xref: NCIT:C32814
xref: SCTID:244244002
xref: UMLS:C0006094 {source="ncithesaurus:Innominate_Artery"}
xref: Wikipedia:Brachiocephalic_artery
is_a: UBERON:0004573 ! systemic artery
relationship: channels_from UBERON:0001508 ! arch of aorta
relationship: connected_to UBERON:0001508 ! arch of aorta
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0007204 ! brachiocephalic vasculature
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001530
name: common carotid artery plus branches
namespace: uberon
def: "A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm]." [Wikipedia:Common_carotid_artery]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "a. carotis communis" RELATED OMO:0003011 [Wikipedia:Common_carotid_artery]
synonym: "carotid artery" BROAD [FMA:3939]
synonym: "carotid artery system" EXACT [EHDAA2:0000217]
synonym: "common carotid artery" EXACT INCONSISTENT [FMA:3939]
synonym: "trunk of common carotid tree" EXACT [FMA:3939]
xref: CALOHA:TS-0116
xref: EHDAA2:0000217
xref: EHDAA:7331
xref: EMAPA:17855
xref: FMA:3939
xref: GAID:479
xref: MA:0001926
xref: MESH:D017536
xref: NCIT:C32352
xref: SCTID:362041005
xref: UMLS:C0162859 {source="ncithesaurus:Common_Carotid_Artery"}
xref: VHOG:0000272
xref: Wikipedia:Common_carotid_artery
is_a: UBERON:0004573 {source="FMA"} ! systemic artery
relationship: connected_to UBERON:0001508 ! arch of aorta
relationship: develops_from UBERON:0004363 {source="Wikipedia"} ! pharyngeal arch artery
relationship: existence_starts_during UBERON:0000068 ! embryo stage
relationship: part_of RO:0002577 ! system
property_value: curator_notes "This class represents the adult and developing structures'" xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI
property_value: editor_note "we follow the FMA and treat the artery as a tree-structure - here we include the internal and external as parts. For the part that excludes the branches, see 'trunk of common carotid artery'" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000011 "in birds and reptiles, develops from arch III and parts of ventral and dorsal aortae" xsd:string

[Term]
id: UBERON:0001533
name: subclavian artery
namespace: uberon
def: "One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta." [https://orcid.org/0000-0002-6601-2165, ISBN:0073040584]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: unverified_taxonomic_grouping
subset: vertebrate_core
synonym: "arteria subclavia" EXACT OMO:0003011 [XAO:0000365]
synonym: "arteria subclavia" RELATED OMO:0003011 [Wikipedia:Subclavian_artery]
synonym: "arterial tree of upper limb" EXACT []
synonym: "PA" RELATED OMO:0003000 []
synonym: "pectoral artery" EXACT []
synonym: "subclavian arterial tree" EXACT []
xref: AAO:0010232
xref: EHDAA2:0001933
xref: EHDAA:4357
xref: EMAPA:17617
xref: FMA:3951
xref: GAID:511
xref: MA:0002045
xref: MESH:D013348
xref: NCIT:C33643
xref: SCTID:265790007
xref: TAO:0005086
xref: UMLS:C0038530 {source="ncithesaurus:Subclavian_Artery"}
xref: Wikipedia:Subclavian_artery
xref: XAO:0000365
xref: ZFA:0005086
is_a: UBERON:0004573 ! systemic artery
relationship: connected_to UBERON:0001508 ! arch of aorta
relationship: develops_from UBERON:0002457 {source="EHDAA2"} ! intersomitic artery
relationship: develops_from UBERON:0005622 {source="EHDAA2"} ! right dorsal aorta
relationship: overlaps UBERON:0000915 ! thoracic segment of trunk
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0004710 ! pectoral appendage
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI
property_value: editor_note "Developmental relationships should be added (intersegmental artery and right dorsal aorta in EHDAA2, occipitovertebral artery in XAO)" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Artery which supplies blood via branches to the various muscles of the shoulder region and to the forelimb.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010232", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "In human anatomy, the subclavian artery is a major artery of the upper thorax that mainly supplies blood to the head and arms. It is located below the clavicle, hence the name. There is a left subclavian and a right subclavian. On the left side of the body, the subclavian comes directly off the arch of aorta. On the right side of the body, the subclavian arises from the relatively short brachiocephalic artery (trunk) when it bifurcates into the subclavian and the right common carotid artery. The usual branches of the subclavian on both sides of the body are the vertebral artery, the internal thoracic artery, the thyrocervical trunk, the costocervical trunk and the dorsal scapular artery. The subclavian becomes the axillary artery at the lateral border of the first rib[WP]" xsd:string {source="Wikipedia:Subclavian_artery"}
property_value: UBPROP:0000001 "The pectoral (subclavian) arteries originate from the dorsal aorta and takes the blood outward into the fin from the paired portion of the dorsal aorta posterior to the last aortic arch. Kimmel et al. 1993[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005086", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0001534
name: right subclavian artery
namespace: uberon
def: "The subclavian artery that supplies the right pectoral appendage." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "arteria subclavia dextra" EXACT OMO:0003011 [FMA:3953, FMA:TA]
xref: EHDAA2:0004514
xref: EMAPA:37384 {source="MA:th"}
xref: FMA:3953
xref: MA:0002047
xref: NCIT:C33490
xref: SCTID:244246000
xref: UMLS:C0226261 {source="ncithesaurus:Right_Subclavian_Artery"}
xref: Wikipedia:Subclavian_artery
is_a: UBERON:0001533 ! subclavian artery
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0001533 ! subclavian artery
intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism
relationship: branching_part_of UBERON:0001529 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! brachiocephalic artery
relationship: connected_to UBERON:0001529 ! brachiocephalic artery
relationship: develops_from UBERON:0003121 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="right arch 4 in human", source="embryology.ch"} ! pharyngeal arch artery 4
relationship: in_right_side_of UBERON:0000468 ! multicellular organism
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "in humans, arises from the relatively short brachiocephalic artery (trunk) when it bifurcates into the subclavian and the right common carotid artery" xsd:string
property_value: UBPROP:0000011 "proximal part arises from right 4th aortic arch in humans" xsd:string

[Term]
id: UBERON:0001555
name: digestive tract
namespace: uberon
def: "A tube extending from the mouth to the anus." [https://github.com/geneontology/go-ontology/issues/7549, Wikipedia:Talk\:Human_gastrointestinal_tract]
subset: human_reference_atlas
subset: uberon_slim
subset: vertebrate_core
synonym: "alimentary canal" NARROW []
synonym: "alimentary tract" NARROW []
synonym: "digestive canal" RELATED [BTO:0000058]
synonym: "digestive tube" EXACT []
synonym: "enteric tract" EXACT [ZFA:0000112]
synonym: "gut" BROAD []
synonym: "gut tube" RELATED []
xref: AAO:0010023
xref: BILA:0000083
xref: BTO:0000511
xref: BTO:0000545
xref: EHDAA2:0000726
xref: EHDAA:518
xref: EMAPA:16247
xref: FBbt:00003125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:45615
xref: galen:AlimentaryTract
xref: MA:0000917
xref: MESH:D041981 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: NCIT:C34082
xref: TAO:0000112
xref: TGMA:0001819
xref: UMLS:C0017189 {source="ncithesaurus:Gastrointestinal_Tract"}
xref: VHOG:0000309
xref: WBbt:0005743
xref: ZFA:0000112
is_a: UBERON:0000025 ! tube
relationship: connects UBERON:0000165 ! mouth
relationship: develops_from UBERON:0007026 ! presumptive gut
relationship: immediate_transformation_of UBERON:0007026 {source="NCBIBook:NBK10107"} ! presumptive gut
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0001007 ! digestive system
property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"}
property_value: RO:0002161 NCBITaxon:41324 {source="DOI:10.1371/journal.pone.0016309"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The alimentary or digestive tract, and associated organs.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000112", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000309", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "FMA also has a term 'gastrointestinal tract', but this includes the liver." xsd:string {external_ontology="FMA"}
property_value: UBPROP:0000012 "we place the MA and EMAPA class here, although the intent is probably a smaller region. See https://github.com/obophenotype/uberon/issues/509" xsd:string {external_ontology="MA"}
property_value: UBPROP:0000013 "we following Kardong in naming the entire tube from mouth to anus the alimentary canal. Kardong calls the portion of this tract that excludes buccal cavity and pharynx the 'alimentary canal', consider adding an extra class for this" xsd:string

[Term]
id: UBERON:0001556
name: lower urinary tract
namespace: uberon
def: "Subdivision of urinary system which consists of the urinary bladder and the urethra." [FMA:45659]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
xref: FMA:45659
xref: galen:LowerUrinaryTract
xref: MA:0002636
xref: SCTID:181420004
is_a: UBERON:0011216 ! organ system subdivision
relationship: has_part UBERON:0000057 ! urethra
relationship: has_part UBERON:0001255 ! urinary bladder
relationship: part_of UBERON:0001008 ! renal system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001558
name: lower respiratory tract
namespace: uberon
def: "The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified]." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Lower_respiratory_tract]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "lower respiratory system" EXACT []
xref: EHDAA2:0001036
xref: EMAPA:16738
xref: FMA:45662
xref: MA:0000435
xref: SCTID:281488008
xref: VHOG:0000382
xref: Wikipedia:Lower_respiratory_tract
is_a: UBERON:0000072 ! proximo-distal subdivision of respiratory tract
relationship: has_part UBERON:0000170 ! pair of lungs
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/9f/Illu_conducting_passages.svg" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_conducting_passages.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001584
name: left subclavian artery
namespace: uberon
def: "The subclavian artery that supplies the left pectoral appendage." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "arteria subclavia (sinistra)" EXACT OMO:0003011 [FMA:4694, FMA:TA]
xref: EMAPA:37100 {source="MA:th"}
xref: FMA:4694
xref: MA:0002046
xref: NCIT:C32972
xref: SCTID:244245001
xref: UMLS:C0226262 {source="ncithesaurus:Left_Subclavian_Artery"}
xref: Wikipedia:Subclavian_artery
is_a: UBERON:0001533 ! subclavian artery
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0001533 ! subclavian artery
intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism
relationship: channels_from UBERON:0001508 ! arch of aorta
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "in humans, branches off the arch of aorta" xsd:string
property_value: UBPROP:0000011 "arises from left intersegmental 6th artery in the region of the 6th -7th cervical segment in humans" xsd:string

[Term]
id: UBERON:0001585
name: anterior vena cava
namespace: uberon
def: "A vein that carries deoxygenated blood from the upper half of the body into the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Superior_vena_cava]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "cranial vena cava" RELATED [VHOG:0001195]
synonym: "precava" RELATED []
synonym: "superior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "superior vena cava" EXACT [FMA:4720]
synonym: "vena cava superior" RELATED OMO:0003011 [BTO:0002683, Wikipedia:Superior_vena_cava]
synonym: "vena maxima" RELATED OMO:0003011 [Wikipedia:Superior_vena_cava]
xref: BTO:0002683
xref: EHDAA2:0001962
xref: EHDAA:8726
xref: EMAPA:18417
xref: FMA:4720
xref: GAID:549
xref: galen:SuperiorVenaCava
xref: MA:0000481
xref: MESH:D014683
xref: NCIT:C12816
xref: SCTID:181368006
xref: UMLS:C0042459 {source="ncithesaurus:Superior_Vena_Cava"}
xref: VHOG:0001195
xref: Wikipedia:Superior_vena_cava
is_a: UBERON:0004087 ! vena cava
intersection_of: UBERON:0004087 ! vena cava
intersection_of: drains UBERON:0000153 ! anterior region of body
relationship: connected_to UBERON:0002078 ! right cardiac atrium
relationship: drains UBERON:0000153 ! anterior region of body
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b4/Venenwinkel.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "Phylogenetic modifications within this basic pattern of arteries and veins are largely correlated with functional changes. In the transition from water to land, gills gave way to lungs, accompanied by the establishment of a pulmonary circulation. In some fishes and certainly in tetrapods, the cardinal veins become less involved in blood return. Instead, the composite, prominent postcava (posterior vena cava) arose to drain the posterior part of the body and the precava (anterior vena cava) developed to drain the anterior part of the body.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001195", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.454-455", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "The mouse has both left and right anterior vena cava. adult humans only have a right. Postnatally the left regresses and becomes non-functional (Wessels and Sedmera 2003). In the mouse, The right pulmonary vein passes dorsal to the right superior vena cava, the left pulmonary dorsal to the left superior vena cava (Biology of the Laboratory Mouse, Green)." xsd:string

[Term]
id: UBERON:0001586
name: internal jugular vein
namespace: uberon
def: "One of two jugular veins that collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted]." [Wikipedia:Internal_jugular_vein]
subset: human_reference_atlas
subset: uberon_slim
synonym: "internal jugular" EXACT [EHDAA2:0000877]
synonym: "internal jugular venous tree" EXACT []
synonym: "vena jugularis interna" RELATED OMO:0003011 [Wikipedia:Internal_jugular_vein]
xref: AAO:0010236
xref: EHDAA2:0000877
xref: EHDAA:5407
xref: EMAPA:17620
xref: FMA:4724
xref: galen:InternalJugularVein
xref: MA:0002157
xref: NCIT:C32849
xref: RETIRED_EHDAA2:0000878
xref: SCTID:181372005
xref: UMLS:C0226550 {source="ncithesaurus:Internal_Jugular_Vein"}
xref: Wikipedia:Internal_jugular_vein
xref: XAO:0000382
is_a: UBERON:0004711 ! jugular vein
relationship: connected_to UBERON:0003711 ! brachiocephalic vein
relationship: drains UBERON:0000955 ! brain
relationship: drains UBERON:0001456 ! face
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e9/Gray562.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Vein which receives many veins draining the palate, brain, and the orbital, nasal, and auditory regions.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010236", ontology="AAO", source="AAO:BJB"}

[Term]
id: UBERON:0001593
name: venous plexus
namespace: uberon
def: "A congregation of multiple veins." [Wikipedia:Venous_plexus]
subset: uberon_slim
synonym: "plexus venosus" RELATED OMO:0003011 [Wikipedia:Venous_plexus]
synonym: "rete venosum" RELATED OMO:0003011 [Wikipedia:Venous_plexus]
synonym: "venous network" EXACT []
xref: EMAPA:36327
xref: FMA:4767
xref: MA:0000069
xref: SCTID:322151008
xref: Wikipedia:Venous_plexus
is_a: UBERON:0004537 ! blood vasculature
is_a: UBERON:0005629 ! vascular plexus
intersection_of: UBERON:0005629 ! vascular plexus
intersection_of: composed_primarily_of UBERON:0001638 ! vein
relationship: composed_primarily_of UBERON:0001638 ! vein
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray585.png" xsd:anyURI

[Term]
id: UBERON:0001605
name: ciliary muscle
namespace: uberon
def: "The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]." [Wikipedia:Ciliary_muscle]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "Bowman`s muscles" RELATED [BTO:0000654]
synonym: "ciliaris" RELATED [Wikipedia:Ciliary_muscle]
synonym: "musculus ciliaris" RELATED OMO:0003011 [Wikipedia:Ciliary_muscle]
synonym: "musculus ciliarus" EXACT [BTO:0000654]
xref: BTO:0000654
xref: EMAPA:35240
xref: FMA:49151
xref: MA:0001269
xref: NCIT:C32315
xref: SCTID:280862009
xref: UMLS:C0559230 {source="ncithesaurus:Ciliary_Muscle"}
xref: Wikipedia:Ciliary_muscle
is_a: UBERON:0003386 {source="MA"} ! smooth muscle of eye
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
is_a: UBERON:0011222 {source="FMA"} ! intra-ocular muscle
relationship: part_of UBERON:0001775 {source="FMA"} ! ciliary body
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/28/Gray872.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001606
name: muscle of iris
namespace: uberon
subset: uberon_slim
synonym: "iris muscle" EXACT []
synonym: "iris muscle organ" EXACT [OBOL:automatic]
synonym: "muscle organ of iris" EXACT [OBOL:automatic]
xref: EMAPA:35448
xref: FMA:49154
xref: MA:0001287
xref: SCTID:280888007
xref: Wikipedia:Iris_muscle
is_a: UBERON:0011222 {source="FMA"} ! intra-ocular muscle
intersection_of: UBERON:0001630 ! muscle organ
intersection_of: part_of UBERON:0001769 ! iris
relationship: part_of UBERON:0001769 ! iris
property_value: editor_note "revisit this, see issue #331" xsd:string
property_value: UBPROP:0000008 "in aves, stromal mesenchymal cells may migrate to the iris and become skeletal" xsd:string
property_value: UBPROP:0000008 "The muscle cells of the iris are smooth muscle in mammals and amphibians, but are striated muscle in birds and reptiles. Many fish have neither, and, as a result, their irides are unable to dilate and contract, so that the pupil always remains of a fixed size[Romer, via WP]" xsd:string

[Term]
id: UBERON:0001607
name: sphincter pupillae
namespace: uberon
def: "A sphincter muscle that is part of the iris." [Wikipedia:Iris_sphincter_muscle]
subset: uberon_slim
synonym: "circular fibers" RELATED [Wikipedia:Iris_sphincter_muscle]
synonym: "constrictor pupillae" RELATED [Wikipedia:Iris_sphincter_muscle]
synonym: "iris constrictor" RELATED []
synonym: "iris constrictor muscle" RELATED [Wikipedia:Iris_sphincter_muscle]
synonym: "iris sphincter" RELATED [Wikipedia:Iris_sphincter_muscle]
synonym: "iris sphincter muscle" EXACT [BTO:0000656]
synonym: "M. sphincter pupillae" EXACT []
synonym: "m. sphincter pupillae" RELATED OMO:0003011 [Wikipedia:Iris_sphincter_muscle]
synonym: "musculus sphincter pupillae" EXACT [BTO:0000656]
synonym: "pupillary constrictor muscle" RELATED [Wikipedia:Iris_sphincter_muscle]
synonym: "pupillary sphincter" RELATED [Wikipedia:Iris_sphincter_muscle]
synonym: "pupillary sphincter muscle" RELATED [Wikipedia:Iris_sphincter_muscle]
synonym: "sphincter muscle of pupil" EXACT [BTO:0000656]
synonym: "sphincter pupillae" RELATED [Wikipedia:Iris_sphincter_muscle]
synonym: "sphincter pupillae muscle" RELATED [Wikipedia:Iris_sphincter_muscle]
synonym: "spincter pupillae" RELATED [Wikipedia:Iris_sphincter_muscle]
xref: BTO:0000656
xref: EMAPA:35788
xref: FMA:49157
xref: MA:0001289
xref: NCIT:C33586
xref: SCTID:280889004
xref: UMLS:C0229189 {source="ncithesaurus:Sphincter_Pupillae_Muscle"}
xref: Wikipedia:Iris_sphincter_muscle
is_a: UBERON:0001606 ! muscle of iris
is_a: UBERON:0004234 {source="BTO"} ! iris smooth muscle
is_a: UBERON:0007521 ! smooth muscle sphincter
intersection_of: UBERON:0004590 ! sphincter muscle
intersection_of: part_of UBERON:0001769 ! iris
relationship: develops_from UBERON:0002346 {source="ISBN:0781772214"} ! neurectoderm
relationship: has_muscle_antagonist UBERON:0001608 {source="dbpedia"} ! dilatator pupillae
relationship: has_muscle_insertion UBERON:0001769 {notes="encircles iris", source="dbpedia"} ! iris
relationship: has_muscle_origin UBERON:0001769 {notes="encircles iris", source="dbpedia"} ! iris
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray878.png" xsd:anyURI
property_value: UBPROP:0000008 "In humans, it functions to constrict the pupil in bright light or during accommodation. Its dimensions are about 0.75 mm wide by 0.15 mm thick. It is controlled by parasympathetic fibers that originate from the Edinger-Westphal nucleus, travel along the oculomotor nerve (CN III), synapse in the ciliary ganglion, and then enter the eye via the short ciliary nerves. Initially, all the myocytes are of the smooth muscle type, but much later in life, so that ultimately most cells are of the striated muscle type. [WP,unvetted]" xsd:string
property_value: UBPROP:0000008 "WP says: It is found in vertebrates and some cephalopods; this class refers to the vertebrate structure" xsd:string
property_value: UBPROP:0000009 "constricts iris" xsd:string

[Term]
id: UBERON:0001608
name: dilatator pupillae
namespace: uberon
def: "A smooth muscle of the eye, running radially in the iris that functions as a dilator. [WP,unvetted]." [Wikipedia:Iris_dilator_muscle]
subset: human_reference_atlas
subset: uberon_slim
synonym: "dilator muscle of pupil" EXACT []
synonym: "dilator of pupil" EXACT []
synonym: "dilator pupillae" EXACT []
synonym: "dilator pupillae muscle" EXACT [Wikipedia:Iris_dilator_muscle]
synonym: "dilator pupillae muscle" RELATED [BTO:0001371]
synonym: "iris dilator" RELATED [Wikipedia:Iris_dilator_muscle]
synonym: "iris dilator muscle" EXACT [BTO:0001371]
synonym: "musculus dilatator pupillae" EXACT OMO:0003011 [FMA:49158, FMA:TA]
synonym: "musculus dilatator pupillae" RELATED OMO:0003011 [Wikipedia:Iris_dilator_muscle]
synonym: "musculus dilator pupillae" RELATED [BTO:0001371]
synonym: "pupil dilator" RELATED [Wikipedia:Iris_dilator_muscle]
synonym: "pupil dilator muscle" RELATED [Wikipedia:Iris_dilator_muscle]
synonym: "pupillary dilator" RELATED [Wikipedia:Iris_dilator_muscle]
synonym: "pupillary dilator muscle" EXACT [Wikipedia:Iris_dilator_muscle]
synonym: "pupillary muscle" RELATED [Wikipedia:Iris_dilator_muscle]
synonym: "radial muscle" RELATED [Wikipedia:Iris_dilator_muscle]
synonym: "radial muscle of iris" EXACT [Wikipedia:Iris_dilator_muscle]
synonym: "radiating fibers" RELATED [Wikipedia:Iris_dilator_muscle]
xref: BTO:0001371
xref: EMAPA:35286
xref: FMA:49158
xref: MA:0001288
xref: NCIT:C32463
xref: SCTID:280890008
xref: UMLS:C0229190 {source="ncithesaurus:Dilator_Pupillae_Muscle"}
xref: Wikipedia:Iris_dilator_muscle
is_a: UBERON:0004234 {source="BTO"} ! iris smooth muscle
relationship: develops_from UBERON:0002346 {source="ISBN:0781772214"} ! neurectoderm
relationship: has_muscle_antagonist UBERON:0001607 {source="dbpedia"} ! sphincter pupillae
relationship: has_muscle_insertion UBERON:0001769 {notes="inner margins of iris", source="dbpedia"} ! iris
relationship: has_muscle_origin UBERON:0001769 {notes="outer margins of iris", source="dbpedia"} ! iris
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray878.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000009 "It is innervated by the sympathetic system, which acts by releasing noradrenaline, which acts on alpha1-receptors. Thus, when presented with a threatening stimuli that activates the fight-or-flight response, this innervation dilates the iris, thus temporarily letting more light reach the retina" xsd:string

[Term]
id: UBERON:0001612
name: facial artery
namespace: uberon
def: "A branch of the external carotid artery that supplies structures of the face. [WP,unvetted]." [Wikipedia:Facial_artery]
subset: human_reference_atlas
subset: uberon_slim
synonym: "arteria maxillaris externa" RELATED OMO:0003011 [Wikipedia:Facial_artery]
synonym: "external maxillary artery" RELATED []
xref: EMAPA:19213
xref: FMA:49549
xref: MA:0001950
xref: NCIT:C32578
xref: SCTID:181328007
xref: UMLS:C0226109 {source="ncithesaurus:Facial_Artery"}
xref: Wikipedia:Facial_artery
is_a: UBERON:0035398 ! branch of external carotid artery
intersection_of: UBERON:0001637 ! artery
intersection_of: connecting_branch_of UBERON:0001070 ! external carotid artery
intersection_of: supplies UBERON:0001456 ! face
relationship: supplies UBERON:0001456 ! face
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/7b/Gray508.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001616
name: maxillary artery
namespace: uberon
def: "An artery that supplies deep structures of the face. It comes just out behind the neck of the mandible. [WP,unvetted]." [Wikipedia:Maxillary_artery]
subset: human_reference_atlas
subset: uberon_slim
synonym: "arteria maxillaris" RELATED OMO:0003011 [Wikipedia:Maxillary_artery]
synonym: "internal maxillary artery" RELATED []
xref: EHDAA2:0001069
xref: EHDAA:7357
xref: EMAPA:17311
xref: FMA:49675
xref: GAID:498
xref: MA:0001919
xref: MESH:D008438
xref: NCIT:C34205
xref: SCTID:181326006
xref: UMLS:C0024949 {source="ncithesaurus:Maxillary_Artery"}
xref: Wikipedia:Maxillary_artery
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: directly_develops_from UBERON:0003118 ! pharyngeal arch artery 1
relationship: connected_to UBERON:0001070 ! external carotid artery
relationship: develops_from UBERON:0003118 ! pharyngeal arch artery 1
relationship: directly_develops_from UBERON:0003118 ! pharyngeal arch artery 1
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/39/Gray510.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000011 "...1st pair undergoes partial regression, the remnants of which becomes part of the maxillary arteries" xsd:string {source="http://download.videohelp.com/vitualis/med/Vascular_Devt.html"}

[Term]
id: UBERON:0001630
name: muscle organ
namespace: uberon
def: "Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]." [GO:0007517]
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "muscle" BROAD [ZFA:0005145]
xref: AAO:0011066
xref: EMAPA:32715
xref: EMAPA:37474 {source="MA:th"}
xref: EV:0100146
xref: FMA:5022
xref: GAID:131
xref: galen:Muscle
xref: MA:0000015
xref: SCTID:71616004
xref: TAO:0005145
xref: VHOG:0001245
xref: XAO:0000172
xref: ZFA:0005145
is_a: UBERON:0000062 ! organ
is_a: UBERON:0005090 ! muscle structure
intersection_of: UBERON:0000062 ! organ
intersection_of: composed_primarily_of UBERON:0002385 ! muscle tissue
relationship: composed_primarily_of UBERON:0002385 ! muscle tissue
relationship: part_of UBERON:0001015 ! musculature
property_value: UBPROP:0000001 "Portion of tissue composed of contractile fibers.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005145", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "It seems clear that the metazoan ancestor inherited from its unicellular descendants an actin cytoskeleton and motor-proteins of the myosin superfamily. Within metazoans, these two molecules were arranged into effective contractile units, the muscles. The basic trends for muscle evolution are already expressed in the diploblastic taxa.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001245", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.75", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "muscular" xsd:string

[Term]
id: UBERON:0001637
name: artery
namespace: uberon
def: "An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]." [AEO:JB]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "arterial subtree" EXACT []
synonym: "arterial system" RELATED []
synonym: "arterial tree organ part" EXACT []
synonym: "arterial vessel" RELATED []
synonym: "arteries" EXACT OMO:0003004 [TAO:0000005]
xref: AAO:0010211
xref: AEO:0000208
xref: BTO:0000573
xref: CALOHA:TS-0054
xref: EFO:0000814
xref: EHDAA2:0000143
xref: EHDAA2:0003253
xref: EMAPA:35147
xref: EV:0100026
xref: FMA:50720
xref: GAID:468
xref: galen:Artery
xref: MA:0000064
xref: MAT:0000034
xref: MESH:D001158
xref: MIAA:0000034
xref: NCIT:C12372
xref: SCTID:362877004
xref: TAO:0000005
xref: UMLS:C0003842 {source="ncithesaurus:Artery"}
xref: VHOG:0001251
xref: Wikipedia:Artery
xref: XAO:0000114
xref: ZFA:0000005
is_a: UBERON:0003509 ! arterial blood vessel
relationship: channels_from UBERON:0000948 ! heart
property_value: editor_note "Note that in FMA an artery is a tree, whereas AEO/JB defines it as a tube; FMA includes a separate class for what it calls the trunk. Classification in this ontology may currently (Jan 2012) represent a mix of both schemes, although we are gradually revising in the direction of the AEO scheme." xsd:string
property_value: UBPROP:0000001 "Part of the circulatory system composed of blood vessels which carry oxygenated blood away from the heart to the rest of the body.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010211", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001251", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "arterial" xsd:string
property_value: UBPROP:0000012 "Some arthropods have primitive arterial systems but this term refers to arteries in a true closed circulatory system." xsd:string
property_value: UBPROP:0000202 FMA:63812

[Term]
id: UBERON:0001638
name: vein
namespace: uberon
def: "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." [Wikipedia:Vein]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "vascular element" RELATED [EMAPA:th]
synonym: "vena" RELATED OMO:0003011 [Wikipedia:Vein]
synonym: "venae" RELATED OMO:0003004 [VHOG:0001743]
synonym: "venous subtree" BROAD []
synonym: "venous tree organ part" EXACT []
synonym: "venous vessel" BROAD []
xref: AAO:0010212
xref: AEO:0000209
xref: BTO:0000234
xref: CALOHA:TS-1108
xref: EFO:0000816
xref: EHDAA2:0003254
xref: EMAPA:35906
xref: EV:0100031
xref: FMA:50723
xref: GAID:492
xref: galen:Vein
xref: MA:0000067
xref: MAT:0000037
xref: MESH:D014680
xref: MIAA:0000037
xref: NCIT:C12814
xref: SCTID:181367001
xref: TAO:0000082
xref: UMLS:C0042449 {source="ncithesaurus:Vein"}
xref: VHOG:0001743
xref: Wikipedia:Vein
xref: XAO:0000115
xref: ZFA:0000082
is_a: UBERON:0003920 ! venous blood vessel
intersection_of: UBERON:0003920 ! venous blood vessel
intersection_of: channel_for UBERON:0013756 ! venous blood
relationship: channel_for UBERON:0013756 ! venous blood
relationship: channels_from UBERON:0001982 ! capillary
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c2/Venous_system_en.svg" xsd:anyURI
property_value: editor_note "TODO - check with MA - vein vs venous blood vessel" xsd:string
property_value: UBPROP:0000001 "Part of the circulatory system composed of blood vessels which carry blood from other organs, tissues, and cells to the heart.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010212", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001743", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "venous" xsd:string
property_value: UBPROP:0000202 FMA:63814

[Term]
id: UBERON:0001639
name: hepatic portal vein
namespace: uberon
def: "A portal vein that transports nutrients from the digestive tract to the liver[Kardong]." [http://sourceforge.net/tracker/?func=detail&aid=3091300&group_id=76834&atid=1205376, ISBN:0073040584, Wikipedia:Hepatic_portal_vein]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "hepatic portal tree" EXACT []
synonym: "HPV" RELATED []
synonym: "liver portal vein" EXACT [OBOL:automatic]
synonym: "portal vein" RELATED INCONSISTENT []
synonym: "portal vein of liver" EXACT [OBOL:automatic]
synonym: "primary hepatic portal vein" RELATED [ZFA:0005090]
synonym: "primary hepatic portal veins" RELATED []
synonym: "vena portae hepatis" RELATED OMO:0003011 [Wikipedia:Hepatic_portal_vein]
xref: AAO:0010214
xref: FMA:50735
xref: MA:0002132
xref: TAO:0005090
xref: VHOG:0000642
xref: Wikipedia:Hepatic_portal_vein
xref: ZFA:0005090
is_a: UBERON:0002017 {source="MA"} ! portal vein
relationship: channels_into UBERON:0002107 ! liver
relationship: develops_from UBERON:0005487 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="Wikipedia:Vitelline_vein"} ! vitelline vein
relationship: overlaps UBERON:0002107 ! liver
relationship: part_of UBERON:0010194 ! hepatic portal system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "Adults of all vertebrates lose the vitelline veins and establish a single large hepatic portal vein (...) by the selective retention of parts of the left and right subintestinals and of several anastomoses that occur between them within and just posterior to the liver.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000642", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.265", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "In humans A vein in the abdominal cavity that drains blood from the gastrointestinal tract and spleen. It is usually formed by the confluence of the superior mesenteric and splenic veins, and also receives blood from the inferior mesenteric, gastric, and cystic veins. The hepatic portal vein is a major component of the hepatic portal system, one of the main portal venous systems in the body. Conditions involving the hepatic portal vein cause considerable illness and death. An important example of such a condition is elevated blood pressure in the hepatic portal vein. This condition, called portal hypertension, is a major complication of cirrhosis worldwide. [WP,unvetted]" xsd:string

[Term]
id: UBERON:0001640
name: celiac artery
namespace: uberon
def: "The first major branch of the abdominal aorta." [Wikipedia:Celiac_artery]
comment: dorsal aorta in Kardong
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "arteria coeliaca" RELATED OMO:0003011 [Wikipedia:Celiac_artery]
synonym: "arteria cœliaca" RELATED OMO:0003011 [Wikipedia:Celiac_artery]
synonym: "celiac tree" EXACT []
synonym: "celiac trunk" RELATED [Wikipedia:Celiac_artery]
synonym: "coeliac artery" EXACT [Wikipedia:Celiac_artery]
synonym: "coeliac axis" RELATED [Wikipedia:Celiac_artery]
synonym: "coeliac trunck" RELATED [Wikipedia:Celiac_artery]
synonym: "coeliac trunk" RELATED [Wikipedia:Celiac_artery]
synonym: "truncus coeliacus" RELATED OMO:0003011 [Wikipedia:Celiac_artery]
synonym: "truncus cœliacus" RELATED OMO:0003011 [Wikipedia:Celiac_artery]
xref: EHDAA2:0004519
xref: EMAPA:35202
xref: FMA:50737
xref: GAID:483
xref: MA:0001931
xref: MESH:D002445
xref: NCIT:C52846
xref: SCTID:181340007
xref: UMLS:C0007569 {source="ncithesaurus:Coeliac_Artery"}
xref: Wikipedia:Celiac_artery
is_a: UBERON:0012254 ! abdominal aorta artery
relationship: develops_from UBERON:0006002 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="Wikipedia"} ! vitelline artery
relationship: indirectly_supplies UBERON:0000160 {source="ISBN:0073040584"} ! intestine
relationship: indirectly_supplies UBERON:0000945 {source="ISBN:0073040584"} ! stomach
relationship: indirectly_supplies UBERON:0002106 {source="ISBN:0073040584"} ! spleen
relationship: indirectly_supplies UBERON:0002107 {source="ISBN:0073040584"} ! liver
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/65/Gray532.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001645
name: trigeminal nerve
namespace: uberon
def: "Cranial nerve that has three branches - the ophthalmic (supplying the skin of the nose and upper jaw), the maxillary and the mandibular (supplying the lower jaw)." [ISBN:0471209627, Wikipedia:Trigeminal_nerve]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "5n" BROAD OMO:0003000 [BIRNLEX:869, NIFSTD:NeuroNames_abbrevSource]
synonym: "CN-V" RELATED []
synonym: "cranial nerve V" RELATED []
synonym: "fifth cranial nerve" EXACT []
synonym: "nerve V" RELATED [NeuroNames:549]
synonym: "nervus trigeminus" EXACT OMO:0003011 [Wikipedia:Trigeminal_nerve]
synonym: "nervus trigeminus" RELATED [BTO:0001072]
synonym: "nervus trigeminus [v]" EXACT OMO:0003011 [FMA:50866, FMA:TA]
synonym: "trigeminal nerve [V]" EXACT []
synonym: "trigeminal nerve tree" EXACT []
synonym: "trigeminal V" EXACT [EHDAA2:0002084]
synonym: "trigeminal v nerve" EXACT []
synonym: "trigeminus" RELATED [BTO:0001072]
xref: AAO:0010470
xref: BAMS:5n
xref: BAMS:nV
xref: BAMS:Vn
xref: BIRNLEX:869
xref: BM:VN
xref: BTO:0001072
xref: EFO:0001402
xref: EHDAA2:0002084
xref: EHDAA:3738
xref: EMAPA:17576
xref: FMA:50866
xref: GAID:726
xref: HBA:9322
xref: MA:0001100
xref: MBA:901
xref: MESH:D014276
xref: MFMO:0000093
xref: NCIT:C12806
xref: neuronames:549 {source="BIRNLEX:869"}
xref: SCTID:362459002
xref: TAO:0000697
xref: UMLS:C0040996 {source="ncithesaurus:Trigeminal_Nerve", source="BIRNLEX:869"}
xref: VHOG:0000704
xref: Wikipedia:Trigeminal_nerve
xref: XAO:0003092
xref: ZFA:0000697
is_a: UBERON:0001785 ! cranial nerve
intersection_of: UBERON:0001785 ! cranial nerve
intersection_of: extends_fibers_into UBERON:0002925 ! trigeminal nucleus
intersection_of: innervates UBERON:0000165 ! mouth
intersection_of: innervates UBERON:0011648 ! jaw muscle
intersection_of: innervates UBERON:1000021 ! skin of face
relationship: capable_of_part_of GO:0050964 {gci_relation="part_of", gci_filler="NCBITaxon:9255", source="PMID:22179203"} ! detection of electrical stimulus involved in electroception
relationship: extends_fibers_into UBERON:0002925 ! trigeminal nucleus
relationship: has_developmental_contribution_from UBERON:0005239 {source="Wikipedia"} ! basal plate metencephalon
relationship: innervates UBERON:0000165 ! mouth
relationship: innervates UBERON:0011648 ! jaw muscle
relationship: innervates UBERON:1000021 ! skin of face
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/9/99/Gray778_Trigeminal.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Nerve consists of motor and sensory components. Ganglion cells of the sensory component form the proximal part of the trigeminal (Gasserian) ganglion. From the ganglion 3 major rami innervate jaws, snout, and buccal roof.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010470", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000704", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.625", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "the ophthalmic usually usually merges with the other two. In some vertebrates, the ophthalmic emerges from the brain separately[Kardong] The trigeminal nerve has 3 branches in mammals - similar branches are present in nonmammalian vertebrates, but in some a separate profundus nerve that corresponds to opthalmic branch in mammls" xsd:string {source="ISBN:0471888893"}

[Term]
id: UBERON:0001651
name: right pulmonary artery
namespace: uberon
def: "The pulmonary artery that supplies the right lung." [UBERON:cjm]
subset: human_reference_atlas
subset: uberon_slim
synonym: "arteria pulmonalis dextra" RELATED OMO:0003011 [Wikipedia:Right_pulmonary_artery]
synonym: "right main pulmonary artery" EXACT []
synonym: "right pulmonary arterial tree" EXACT []
xref: EMAPA:37378 {source="MA:th"}
xref: FMA:50872
xref: galen:RightPulmonaryArtery
xref: MA:0002500
xref: NCIT:C33489
xref: SCTID:244235003
xref: UMLS:C0923924 {source="ncithesaurus:Right_Pulmonary_Artery"}
xref: Wikipedia:Right_pulmonary_artery
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0002167 ! right lung
relationship: connected_to UBERON:0002333 ! pulmonary trunk
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0002167 ! right lung
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray504.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI
property_value: editor_note "TODO - add class 'pulmonary artery tree organ'" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001652
name: left pulmonary artery
namespace: uberon
def: "The pulmonary artery that supplies the left lung." [UBERON:cjm]
subset: human_reference_atlas
subset: uberon_slim
synonym: "arteria pulmonalis sinistra" RELATED OMO:0003011 [Wikipedia:Left_pulmonary_artery]
synonym: "left main pulmonary artery" EXACT []
synonym: "left pulmonary arterial tree" EXACT []
xref: EMAPA:37097 {source="MA:th"}
xref: FMA:50873
xref: galen:LeftPulmonaryArtery
xref: MA:0002032
xref: NCIT:C32971
xref: SCTID:244234004
xref: UMLS:C0923925 {source="ncithesaurus:Left_Pulmonary_Artery"}
xref: Wikipedia:Left_pulmonary_artery
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0002168 ! left lung
relationship: connected_to UBERON:0002333 ! pulmonary trunk
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0002168 ! left lung
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray504.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI
property_value: editor_note "TODO - add class 'pulmonary artery tree organ'" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001653
name: facial vein
namespace: uberon
def: "The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]." [Wikipedia:Facial_vein]
subset: human_reference_atlas
subset: uberon_slim
synonym: "anterior facial vein" RELATED INCONSISTENT [Wikipedia:Facial_vein]
synonym: "face vein" EXACT [OBOL:automatic]
synonym: "vein of face" EXACT [OBOL:automatic]
synonym: "vena facialis anterior" RELATED OMO:0003011 [Wikipedia:Facial_vein]
xref: AAO:0010513
xref: EMAPA:19220
xref: FMA:50874
xref: MA:0002115
xref: NCIT:C32579
xref: SCTID:181374006
xref: UMLS:C0226532 {source="ncithesaurus:Facial_Vein"}
xref: Wikipedia:Facial_vein
is_a: UBERON:0003496 ! head blood vessel
is_a: UBERON:0009141 ! craniocervical region vein
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0001456 ! face
relationship: tributary_of UBERON:0001586 {source="FMA"} ! internal jugular vein
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Vein which collects blood from muscles of the head and drains into the external jugular vein.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010513", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000012 "MA and NCITA also has 'anterior facial vein'" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001675
name: trigeminal ganglion
namespace: uberon
def: "The cranial ganglion that is associated with and extends fibers into the trigeminal nerve." [http://orcid.org/0000-0002-6601-2165, http://www.ncbi.nlm.nih.gov/books/NBK53171, https://github.com/obophenotype/uberon/issues/693]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "5th ganglion" EXACT [ZFA:0000295]
synonym: "fifth ganglion" EXACT [ZFA:0000295]
synonym: "fused trigeminal ganglion" NARROW SENSU [NCBITaxon:32524]
synonym: "ganglion of trigeminal complex" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "ganglion of trigeminal nerve" RELATED [BTO:0001231]
synonym: "ganglion semilunare" RELATED OMO:0003011 [Wikipedia:Trigeminal_ganglion]
synonym: "ganglion trigeminale" RELATED OMO:0003011 [BTO:0001231, Wikipedia:Trigeminal_ganglion]
synonym: "Gasser's ganglion" RELATED [BTO:0001231]
synonym: "Gasserian ganglia" RELATED OMO:0003004 [Wikipedia:Trigeminal_ganglion]
synonym: "Gasserian ganglion" EXACT [Wikipedia:Trigeminal_ganglion]
synonym: "gV" RELATED []
synonym: "semilunar ganglion" EXACT [ISBN:0471888893]
synonym: "trigeminal ganglia" RELATED OMO:0003004 []
synonym: "trigeminal V ganglion" EXACT [MA:0001080]
synonym: "trigeminus ganglion" RELATED []
xref: AAO:0011107
xref: BAMS:5Gn
xref: BAMS:GV
xref: BTO:0001231
xref: EFO:0000903
xref: EHDAA2:0002085
xref: EHDAA:2113
xref: EMAPA:16797
xref: FMA:52618
xref: GAID:725
xref: MA:0001080
xref: MAT:0000511
xref: MESH:D012668
xref: NCIT:C62642
xref: neuronames:1402
xref: SCTID:244449009
xref: TAO:0000295
xref: UMLS:C0040995 {source="ncithesaurus:Trigeminal_Ganglion"}
xref: VHOG:0000694
xref: Wikipedia:Trigeminal_ganglion
xref: XAO:0000427
xref: XAO:0000428
xref: ZFA:0000295
is_a: UBERON:0001714 ! cranial ganglion
is_a: UBERON:0001800 {source="ncithesaurus"} ! sensory ganglion
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0001714 ! cranial ganglion
intersection_of: extends_fibers_into UBERON:0001645 ! trigeminal nerve
relationship: develops_from UBERON:0006304 ! future trigeminal ganglion
relationship: extends_fibers_into UBERON:0001645 ! trigeminal nerve
relationship: immediate_transformation_of UBERON:0006304 {source="Bgee:AN"} ! future trigeminal ganglion
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/69/Gray776.png" xsd:anyURI
property_value: editor_note "consider renaming this 'trigeminal ganglion complex'. The complex may be fused (amniotes) partially fused (xenopus) or separate (sharks)" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/ANiknejad
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly
property_value: UBPROP:0000001 "A prominent collection of touch-sensory neurons of the trigeminal or fifth cranial nerve, positioned beside the brain between the eye and the ear. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000295", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000008 "In Xenopus, the profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24." xsd:string {source="PMID:21452441", source="XAO:0004093"}

[Term]
id: UBERON:0001676
name: occipital bone
namespace: uberon
def: "The bone at the lower, posterior part of the skull." [ISBN:0-683-40008-8, MP:0005269]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "occipital complex" RELATED [http://palaeos.com/vertebrates/bones/braincase/occiput.html]
synonym: "occipital squama" RELATED []
synonym: "os occipitale" RELATED OMO:0003011 [Wikipedia:Occipital_bone]
xref: EMAPA:25112
xref: FMA:52735
xref: GAID:227
xref: MA:0001468
xref: MESH:D009777
xref: NCIT:C12757
xref: SCTID:181796003
xref: UMLS:C0028784 {source="ncithesaurus:Occipital_Bone"}
xref: Wikipedia:Occipital_bone
is_a: UBERON:0010428 {source="FMA"} ! flat bone
is_a: UBERON:0011164 ! neurocranium bone
relationship: connected_to UBERON:0001092 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! vertebral bone 1
relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone
relationship: develops_from UBERON:0003089 {source="PMID:11523816"} ! sclerotome
relationship: only_in_taxon NCBITaxon:117570 {source="WP"} ! Teleostomi
relationship: overlaps UBERON:0002241 {notes="basi paired exo and supra occipital bones", source="MA-modified"} ! chondrocranium
relationship: overlaps UBERON:0003113 {notes="interparietal (postparietal)"} ! dermatocranium
relationship: part_of UBERON:0005902 {source="FMA"} ! occipital region
relationship: surrounds UBERON:0003687 ! foramen magnum
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/27/Gray194.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "formed from the sclerotome of the occipital somites. It is not present in living or fossil agnathans or cartilaginous fishes, but appears to have arisen in parallel in many bony fishes. Incorporation of the occipital ver- tebrae into the skull was associated with the annexation of the upper part of the spinal cord into the brain, together with the first 2 spinal nerves as cranial nerves XI and XII" xsd:string {source="PMID:11523816"}
property_value: UBPROP:0000008 "fusion of basi-, exo- and supra-occipitals (and maybe tabular)" xsd:string {source="Kardong"}

[Term]
id: UBERON:0001677
name: sphenoid bone
namespace: uberon
def: "An unpaired bone situated at the base of the skull in front of the temporal bone and basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the orbit. Its shape somewhat resembles that of a butterfly or bat with its wings extended." [Wikipedia:Sphenoid_bone]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "butterfly bone" RELATED [Wikipedia:Sphenoid_bone]
synonym: "os sphenoidale" EXACT OMO:0003011 [FMA:52736, FMA:TA]
synonym: "os sphenoidale" RELATED OMO:0003011 [Wikipedia:Sphenoid_bone]
synonym: "os sphenoidum" RELATED [Wikipedia:Sphenoid_bone]
synonym: "sphenoid" EXACT []
synonym: "sphenoid complex" RELATED []
synonym: "sphenoidal bone" EXACT []
xref: CALOHA:TS-2343
xref: EMAPA:18340
xref: FMA:52736
xref: GAID:230
xref: MA:0001472
xref: MESH:D013100
xref: NCIT:C12790
xref: SCTID:272676008
xref: UMLS:C0037884 {source="ncithesaurus:Sphenoid_Bone"}
xref: Wikipedia:Sphenoid_bone
is_a: UBERON:0002513 ! endochondral bone
is_a: UBERON:0003462 ! facial bone
is_a: UBERON:0008193 {source="FMA"} ! pneumatized bone
is_a: UBERON:0015060 ! sphenoid endochondral element
intersection_of: UBERON:0015060 ! sphenoid endochondral element
intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue
relationship: connected_to UBERON:0000209 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! tetrapod frontal bone
relationship: connected_to UBERON:0001676 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! occipital bone
relationship: connected_to UBERON:0001679 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! ethmoid bone
relationship: connected_to UBERON:0002396 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! vomer
relationship: develops_from UBERON:0009193 {source="cjm"} ! sphenoid cartilage element
relationship: overlaps UBERON:0002241 {notes="orbito pre and basi sphenoid"} ! chondrocranium
relationship: overlaps UBERON:0003113 {notes="pterygoid process"} ! dermatocranium
relationship: overlaps UBERON:0008895 {notes="alisphenoid"} ! splanchnocranium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "part of viscerocranium (facial skeleton) in FMA" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001679
name: ethmoid bone
namespace: uberon
def: "A bone in the skull that separates the nasal cavity from the brain. As such, it is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to a spongy construction. The ethmoid bone is one of the bones that makes up the orbit of the eye[WP]." [Wikipedia:Ethmoid_bone]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "ethmoid" EXACT [FMA:52740]
synonym: "ethmoidal bone" EXACT [MP:0000101]
synonym: "os ethmoidale" EXACT OMO:0003011 [FMA:52740, FMA:TA, Wikipedia:Ethmoid]
xref: BTO:0004140
xref: EMAPA:19018
xref: FMA:52740
xref: GAID:212
xref: MA:0001483
xref: MESH:D005004
xref: NCIT:C12711
xref: SCTID:272674006
xref: UMLS:C0015027 {source="ncithesaurus:Ethmoid_Bone"}
xref: VHOG:0001317
xref: Wikipedia:Ethmoid_bone
is_a: UBERON:0002513 {source="ISBN:0073040584"} ! endochondral bone
is_a: UBERON:0003462 ! facial bone
is_a: UBERON:0011164 ! neurocranium bone
relationship: connected_to UBERON:0000209 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! tetrapod frontal bone
relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone
relationship: connected_to UBERON:0002396 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! vomer
relationship: contributes_to_morphology_of UBERON:0011156 ! facial skeleton
relationship: develops_from UBERON:0006227 {evidence="definitional"} ! ethmoid bone primordium
relationship: part_of UBERON:0002517 ! basicranium
relationship: part_of UBERON:0011241 ! ethmoid region
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A light spongy bone located between the eye sockets, forming part of the walls and septum of the superior nasal cavity, and containing perforations for the passage of olfactory nerve fibers. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001317", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/ethmoid+bone"}
property_value: UBPROP:0000003 "The ethmoid region of the chondrocranium and the nasal capsules, which were largely unossified in early tetrapods and ancestral amniotes, are represented in mammals by the ethmoid and turbinates bones, respectively.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001317", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.259", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "ethmoidal" xsd:string
property_value: UBPROP:0000008 "todo - homology e.g. mesethmoid of teleost" xsd:string
property_value: UBPROP:0000012 "Note the WP states the Neurocranium contains the ethmoid bone, both MA and FMA place the ethmoid as part of the viscerocranium. FMA also has it in neurocranium (via basicranium). Ideally we would have non-overlapping divisions of the skull, but for now we follow FMA" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001697
name: orbit of skull
namespace: uberon
def: "Subdivision of skeleton that is an anterolateral part of the cranium and structurally supports the eye. Includes bones formed and located in sclerotic layer of eyeball." [http://orcid.org/0000-0002-6601-2165, TAO:0001410, Wikipedia:Orbit_(anatomy)]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "bony orbit" EXACT []
synonym: "eye socket" EXACT []
synonym: "orbit" RELATED [ZFA:0001410]
synonym: "orbit of skull" EXACT [FMA:53074]
xref: BTO:0004687
xref: FMA:53074
xref: GAID:223
xref: galen:Orbit
xref: MA:0002482
xref: MESH:D009915
xref: NCIT:C12347
xref: TAO:0001410
xref: UMLS:C0029180 {source="ncithesaurus:Orbit"}
xref: Wikipedia:Orbit_(anatomy)
xref: XAO:0003171
xref: ZFA:0001410
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0010912 ! subdivision of skeleton
is_a: UBERON:0015212 ! lateral structure
relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton
relationship: location_of UBERON:0000019 ! camera-type eye
relationship: part_of UBERON:0004088 ! orbital region
relationship: part_of UBERON:0011156 ! facial skeleton
property_value: UBPROP:0000001 "Anatomical cluster that is a anterolateral part of the cranium and structurally supports the eye.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001410", ontology="TAO", source="TAO:MAH"}
property_value: UBPROP:0000012 "in FMA, this overlaps with bones such as the maxilla and sphenoid; in ZFA, individual bones are part of the orbit" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001703
name: neurocranium
namespace: uberon
def: "Subdivision of skeletal system that surrounds and protects the brain. Includes the skull base, sensory capsules and the central part of the skull roof." [PMID:11523816, TAO:MAH, Wikipedia:Neuroranium, ZFA:0001580]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "brain box" EXACT []
synonym: "brain case" RELATED [ZFA:0001580]
synonym: "brain pan" RELATED [http://www.thefreedictionary.com/braincase]
synonym: "braincase" RELATED [ZFA:0001580]
xref: AAO:0010153
xref: EHDAA2:0000243
xref: EMAPA:17681
xref: FMA:53672
xref: MA:0000317
xref: SCTID:361731002
xref: TAO:0001580
xref: Wikipedia:Neuroranium
xref: XAO:0003170
xref: ZFA:0001580
is_a: UBERON:0011158 {source="FMA"} ! primary subdivision of skull
relationship: develops_from UBERON:0004761 ! cartilaginous neurocranium
relationship: location_of UBERON:0000955 ! brain
relationship: part_of UBERON:0003128 ! cranium
relationship: protects UBERON:0000955 ! brain
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anatomical cluster that consists of the cartilages and bones that surround the brain.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001580", ontology="TAO", source="TAO:MAH"}
property_value: UBPROP:0000007 "neurocranial" xsd:string
property_value: UBPROP:0000010 "It includes the following bones: Ethmoid bone, Frontal bone, Occipital bone, Parietal bone, Sphenoid bone, Temporal bone. The term cranium can be ambiguous, in that it can refer to the neurocranium, or the neurocranium and the Facial skeleton" xsd:string
property_value: UBPROP:0000011 "The cartilaginous parts of the neurocranium undergo endochondral ossification in most species; ossification has been lost in cartilaginous fishes, but the cartilaginous condition of the skull of lampreys is considered to be primitive (Kardong, 1995)[PMID:11523816]. The neurocranium arises from paraxial mesoderm in the head (first five somites and the unsegmented somitomeres rostral to the first somite) and from ectoderm via the neural crest. In Chondrichthyes and other cartilaginous vertebrates this portion of the cranium does not ossify; it is not replaced via endochondral ossification[WP]." xsd:string {source="WP"}
property_value: UBPROP:0000012 "It seems MA uses 'neurocranium' as a synonym for chondrocranium. Note there are currently some structures part of both viscero and neurocranium - ethmoid, zyogomatic, ..." xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001708
name: jaw skeleton
namespace: uberon
def: "Subdivision of skeleton which includes upper and lower jaw skeletons." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Jaw]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "anterior splanchnocranium" RELATED []
synonym: "jaw" EXACT [MA:0001905]
synonym: "jaw cartilage" EXACT [ZFA:0001227]
synonym: "jaws" RELATED []
synonym: "mandibular arch" RELATED [TAO:0001227]
synonym: "mandibular arch skeleton" EXACT [ZFA:0001227]
synonym: "oral jaw skeleton" RELATED []
synonym: "pharyngeal arch 1 skeleton" RELATED []
synonym: "visceral arch 1" RELATED []
xref: AAO:0000988
xref: BTO:0001749
xref: EMAPA:35455
xref: FMA:54396
xref: GAID:214
xref: galen:Jaw
xref: MA:0001905
xref: MESH:D007568
xref: NCIT:C48821
xref: SCTID:181811001
xref: TAO:0001227
xref: UMLS:C0022359 {source="ncithesaurus:Jaw"}
xref: Wikipedia:Jaw
xref: ZFA:0001227
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0010912 ! subdivision of skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: skeleton_of UBERON:0011595 ! jaw region
relationship: capable_of NBO:0000073 ! chewing
relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata <vertebrates>
relationship: overlaps UBERON:0008895 ! splanchnocranium
relationship: part_of UBERON:0011156 {source="cjm"} ! facial skeleton
relationship: part_of UBERON:0011595 ! jaw region
relationship: skeleton_of UBERON:0011595 ! jaw region
property_value: editor_note "TODO - move ZFA:0001227 (it is the entire jaw skeleton)." xsd:string
property_value: UBPROP:0000001 "Skeletal and cartilage elements of the first pharyngeal arch.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001227", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000011 "There are cellular contributions from all three embryonic germ layers: pharyngeal mesoderm, endoderm and neural crest that migrates out of the ectoderm (Noden, 1983)." xsd:string
property_value: UBPROP:0000012 "in FMA, the jaw is an organism subdivision cluster, and includes mucosal tissue such as the gingiva as parts. It appears to be skeletal in MA (and has teeth as parts). It is reasonable to assume that ZFA and XAO consider the upper and lower jaws to be skeletal elements or clusters. EHDAA2 also considers these clusters. TODO - follow EHDAA2 model. These arbitrary differences in terminology and classification have to be reconciled with the genuine well-known biological differences in the skeletal elements across vertebrates" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001709
name: upper jaw region
namespace: uberon
def: "Subdivision of head that consists of the upper jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Upper_jaw]
comment: See notes for jaw w.r.t skeletal element vs subdivision of head.
subset: uberon_slim
subset: vertebrate_core
synonym: "alveolodental arch of bimaxilla" RELATED [FMA:59399]
synonym: "dorsal mandibular arch" RELATED []
synonym: "dorsal pharyngeal arch 1" RELATED INCONSISTENT []
synonym: "maxillary part of mouth" EXACT [FMA:59399]
synonym: "maxillary part of mouth proper" RELATED [FMA:59399]
synonym: "palatoquadrate arch" RELATED INCONSISTENT []
synonym: "upper pharyngeal jaws" RELATED []
xref: AAO:0000620
xref: EHDAA2:0002118
xref: EHDAA2:0004607
xref: EHDAA:8025
xref: EMAPA:17924
xref: FMA:59399
xref: ncithesaurus:Upper_Jaw
xref: SCTID:362636001
xref: VHOG:0000454
xref: Wikipedia:Upper_jaw
is_a: UBERON:0000475 ! organism subdivision
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
intersection_of: UBERON:0000475 ! organism subdivision
intersection_of: has_skeleton UBERON:0003277 ! skeleton of upper jaw
disjoint_from: UBERON:0001710 ! lower jaw region
relationship: has_skeleton UBERON:0003277 ! skeleton of upper jaw
relationship: part_of UBERON:0004089 ! midface
relationship: part_of UBERON:0011595 ! jaw region
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/a7/Gray189.png" xsd:anyURI
property_value: RO:0002171 UBERON:0001710
property_value: UBPROP:0000001 "Superior maxillary arch located on the anterior and lateral sides of the skull.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000620", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000003 "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000454", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "Note isa/partof difference MA/FMA" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001710
name: lower jaw region
namespace: uberon
def: "Subdivision of head that consists of the lower jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]." [Wikipedia:Lower_jaw]
comment: See notes for jaw w.r.t skeletal element vs subdivision of head
subset: efo_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "lower part of mouth" RELATED []
synonym: "mandibular part of mouth" EXACT [FMA:59398]
synonym: "mandibular series" RELATED []
xref: AAO:0000272
xref: EFO:0003660
xref: EHDAA2:0001018
xref: EHDAA:7995
xref: EMAPA:17906
xref: FMA:59398
xref: MESH:D008334
xref: ncithesaurus:Lower_Jaw
xref: SCTID:362637005
xref: VHOG:0000453
xref: Wikipedia:Lower_jaw
is_a: UBERON:0000475 ! organism subdivision
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
intersection_of: UBERON:0000475 ! organism subdivision
intersection_of: has_skeleton UBERON:0003278 ! skeleton of lower jaw
relationship: develops_from UBERON:0005867 {source="Wikipedia:Mandibular_prominence"} ! mandibular prominence
relationship: has_skeleton UBERON:0003278 ! skeleton of lower jaw
relationship: part_of UBERON:0011595 ! jaw region
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png" xsd:anyURI
property_value: RO:0002171 UBERON:0001709
property_value: UBPROP:0000001 "Inferior mandibular arch located on the anterior and lateral sides of the skull.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000272", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000003 "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000453", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "Note isa/partof difference MA/FMA" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001714
name: cranial ganglion
namespace: uberon
alt_id: UBERON:0003213
alt_id: UBERON:0026601
def: "The groups of nerve cell bodies associated with the twelve cranial nerves." [ISBN:0-683-40008-8, MGI:csmith, MP:0001081, PMID:9362461]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cranial ganglia" RELATED []
synonym: "cranial ganglion" EXACT []
synonym: "cranial ganglion part of peripheral nervous system" EXACT [BIRNLEX:2597]
synonym: "cranial ganglion/nerve" EXACT []
synonym: "cranial nerve ganglion" EXACT []
synonym: "cranial neural ganglion" EXACT []
synonym: "cranial neural tree organ ganglion" EXACT [OBOL:automatic]
synonym: "ganglion of cranial nerve" EXACT [FMA:54502]
synonym: "ganglion of cranial neural tree organ" EXACT [OBOL:automatic]
synonym: "head ganglion" RELATED []
synonym: "presumptive cranial ganglia" RELATED [ZFA:0000013]
xref: BIRNLEX:2597
xref: BTO:0000106
xref: EFO:0000902
xref: EMAPA:16659
xref: FMA:54502
xref: MA:0000213
xref: MA:0000214
xref: MAT:0000200
xref: MIAA:0000200
xref: SCTID:244448001
xref: TAO:0000013
xref: VHOG:0000076
xref: Wikipedia:Cranial_nerve_ganglion
xref: XAO:0000027
xref: ZFA:0000013
is_a: UBERON:0000045 ! ganglion
intersection_of: UBERON:0000045 ! ganglion
intersection_of: extends_fibers_into UBERON:0034713 ! cranial neuron projection bundle
relationship: extends_fibers_into UBERON:0034713 ! cranial neuron projection bundle
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0000033 ! head
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Ganglion which is located in the head.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000013", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0001731
name: cavity of pharynx
namespace: uberon
def: "An anatomical space that is enclosed by a pharynx." [OBOL:automatic]
synonym: "cavitas pharyngealis" RELATED OMO:0003011 []
synonym: "cavitas pharyngis" RELATED [BTO:0002097]
synonym: "lumen of pharynx" EXACT []
synonym: "pharyngeal cavity" EXACT []
xref: AAO:0010435
xref: BSA:0000113
xref: BTO:0002097
xref: EMAPA:18381
xref: FMA:54935
xref: SCTID:180543003
xref: XAO:0000105
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0006562 ! pharynx
relationship: develops_from UBERON:0001041 {source="XAO"} ! foregut
relationship: luminal_space_of UBERON:0006562 ! pharynx
relationship: part_of UBERON:0006562 ! pharynx
property_value: UBPROP:0000008 "See notes for pharynx - as a grouping class this is probably too bad. We exclude WBbt:0005790 (pharyngeal lumen) because of the developmental relationship" xsd:string
property_value: UBPROP:0000011 "TOODO check" xsd:string

[Term]
id: UBERON:0001766
name: anterior chamber of eyeball
namespace: uberon
def: "The space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens." [MESH:A09.371.060.067, MP:0005205]
subset: pheno_slim
synonym: "anterior chamber" EXACT [HP:0000593, MP:0010709]
synonym: "anterior chamber of eye" EXACT []
synonym: "camera anterior" EXACT []
synonym: "camera anterior bulbi" RELATED [BTO:0002084]
synonym: "camera anterior bulbi oculi" RELATED OMO:0003011 [Wikipedia:Anterior_chamber_of_eyeball]
synonym: "camera oculi anterior" RELATED [BTO:0002084]
synonym: "eye anterior chamber" EXACT []
xref: BTO:0002084
xref: EHDAA2:0000129
xref: EHDAA:9033
xref: EMAPA:18231
xref: FMA:58078
xref: GAID:889
xref: MA:0000262
xref: MESH:D000867
xref: NCIT:C12667
xref: SCTID:181160009
xref: UMLS:C0003151 {source="ncithesaurus:Anterior_Chamber_of_the_Eye"}
xref: VHOG:0001431
xref: Wikipedia:Anterior_chamber_of_eyeball
is_a: UBERON:0006311 {source="FMA"} ! chamber of eyeball
relationship: contributes_to_morphology_of UBERON:0001801 ! anterior segment of eyeball
relationship: part_of UBERON:0001801 ! anterior segment of eyeball
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI
property_value: UBPROP:0000001 "The part of the eyeball between the cornea and the iris, filled with aqueous humor. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001431", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/anterior+chamber"}
property_value: UBPROP:0000012 "space in EHDAA2 - consider adding Cavity of anterior chamber of eyeball" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0001768
name: uvea
namespace: uberon
def: "The pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]." [MP:0005197, Wikipedia:Uvea]
subset: pheno_slim
subset: uberon_slim
synonym: "pars iridica retinae" RELATED [Wikipedia:Uvea]
synonym: "tunica vasculatis oculi" RELATED [Wikipedia:Uvea]
synonym: "tunica vasculosa bulbi" RELATED OMO:0003011 [Wikipedia:Uvea]
synonym: "tunica vasculosa of eyeball" EXACT [FMA:58103]
synonym: "uvea" EXACT [FMA:58103]
synonym: "uveal tract" EXACT [FMA:58103]
synonym: "vascular layer of eyeball" RELATED [FMA:58103]
xref: CALOHA:TS-2228
xref: EMAPA:35901
xref: FMA:58103
xref: GAID:912
xref: MA:0002480
xref: MESH:D014602
xref: NCIT:C12811
xref: SCTID:280648000
xref: UMLS:C0042160 {source="ncithesaurus:Uvea"}
xref: Wikipedia:Uvea
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0004923 {source="FMA"} ! organ component layer
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye
relationship: has_part UBERON:0001769 ! iris
relationship: has_part UBERON:0001775 ! ciliary body
relationship: has_part UBERON:0001776 ! optic choroid
relationship: part_of UBERON:0001801 ! anterior segment of eyeball
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/eb/Gray869.png" xsd:anyURI
property_value: editor_note "TODO - check child terms, isa vs partof. See also MA:0001284 ! tunica vasculosa plexus" xsd:string
property_value: RO:0002175 NCBITaxon:7955 {source="DOI:10.1177/0192623311409597"}
property_value: UBPROP:0000007 "uveal" xsd:string

[Term]
id: UBERON:0001769
name: iris
namespace: uberon
def: "The adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye." [ISBN:0-683-40008-8, MP:0001322]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "anterior uvea" RELATED []
synonym: "irides" RELATED OMO:0003004 []
synonym: "irises" RELATED OMO:0003004 [VHOG:0000101]
xref: AAO:0010347
xref: BTO:0000653
xref: CALOHA:TS-0491
xref: EFO:0004245
xref: EMAPA:19154
xref: EV:0100345
xref: FMA:58235
xref: GAID:917
xref: MA:0000273
xref: MESH:D007498
xref: NCIT:C12737
xref: SCTID:181164000
xref: TAO:0001238
xref: UMLS:C0022077 {source="ncithesaurus:Iris"}
xref: VHOG:0000101
xref: Wikipedia:Iris_(anatomy)
xref: XAO:0000185
xref: ZFA:0001238
is_a: UBERON:0000481 ! multi-tissue structure
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: contributes_to_morphology_of UBERON:0011892 ! anterior uvea
relationship: develops_from UBERON:0004128 {source="XAO"} ! optic vesicle
relationship: part_of UBERON:0011892 ! anterior uvea
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The opaque muscular contractile diaphragm suspended in the aqueous humour in front of the lens of the eye. The organ is perforated by the pupil and continues peripherally with the ciliary body. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000101", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000101", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "iridial" xsd:string
property_value: UBPROP:0000008 "The avian iris and ciliary body undergoes a transition from smooth-to-striated muscle during embryonic development [DOI:dx.doi.org/10.1006/dbio.1998.9019]" xsd:string

[Term]
id: UBERON:0001772
name: corneal epithelium
namespace: uberon
def: "The smooth stratified squamous epithelium that covers the outer surface of the cornea." [MESH:A09.371.060.217.325, MGI:smb, MP:0006000]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "anterior corneal epithelium" EXACT []
synonym: "anterior endothelium of cornea" RELATED [BTO:0000287]
synonym: "cornea epithelial tissue" EXACT [OBOL:automatic]
synonym: "cornea epithelium" EXACT [OBOL:automatic]
synonym: "e. anterius corneae" RELATED OMO:0003011 [Wikipedia:Corneal_epithelium]
synonym: "endothelium anterius corneae" RELATED [BTO:0000287]
synonym: "endothelium camerae anterioris bulbi" RELATED [BTO:0000287]
synonym: "endothelium corneale" RELATED [BTO:0000287]
synonym: "epithelial tissue of cornea" EXACT [OBOL:automatic]
synonym: "epithelium anterius (cornea)" EXACT []
synonym: "epithelium anterius corneae" EXACT OMO:0003011 [FMA:58263, FMA:TA]
synonym: "epithelium corneæ anterior layer" EXACT []
synonym: "epithelium of cornea" EXACT []
synonym: "epithelium posterius corneae" RELATED [BTO:0000287]
synonym: "external epithelium of cornea" EXACT []
xref: BTO:0000287
xref: CALOHA:TS-0173
xref: EFO:0001917
xref: EHDAA2:0000319
xref: EMAPA:17162
xref: FMA:58263
xref: GAID:895
xref: MA:0001243
xref: MESH:D019573
xref: NCIT:C12928
xref: SCTID:368825001
xref: TAO:0002187
xref: UMLS:C0459875 {source="ncithesaurus:Corneal_Epithelium"}
xref: Wikipedia:Corneal_epithelium
xref: ZFA:0001683
is_a: UBERON:0000488 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! atypical epithelium
is_a: UBERON:0010304 {gci_relation="part_of", gci_filler="NCBITaxon:7955"} ! non-keratinized stratified squamous epithelium
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0015808 ! eye epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: bounding_layer_of UBERON:0000964 ! cornea
relationship: bounding_layer_of UBERON:0000964 ! cornea
relationship: contributes_to_morphology_of UBERON:0000964 ! cornea
relationship: develops_from UBERON:0000076 {source="ISBN:0781772214"} ! external ectoderm
relationship: part_of UBERON:0000964 ! cornea
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Portion of tissue comprised of four to six layers of nonkeratinized, stratified squamous cells and represents approximately 60% of the thickness of the cornea.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002187", ontology="TAO", source="ZFIN:ZDB-PUB-061010-3"}
property_value: UBPROP:0000008 "In Humans: It consists of several layers of cells. The cells of the deepest layer are columnar; then follow two or three layers of polyhedral cells, the majority of which are prickle cells similar to those found in the stratum mucosum of the cuticle. Lastly, there are three or four layers of squamous cells, with flattened nuclei" xsd:string
property_value: UBPROP:0000008 "In zebrafish: nonpigmented, stratified squamous nonkeratinizing epithelial cells, attached to a thick basement membrane that is considered to be analogous to the Bowman's membrane in mammals" xsd:string

[Term]
id: UBERON:0001773
name: sclera
namespace: uberon
def: "Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]." [Wikipedia:Sclera, ZFIN:ZDB-PUB-050701-15]
comment: Disease notes: implicated in rheumatoid arthritis.
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "scleral capsule" RELATED []
xref: AAO:0010354
xref: BTO:0001606
xref: EMAPA:19027
xref: EV:0100342
xref: FMA:58269
xref: GAID:911
xref: MA:0000280
xref: MESH:D012590
xref: NCIT:C12784
xref: SCTID:181163006
xref: UMLS:C0036410 {source="ncithesaurus:Sclera"}
xref: VHOG:0001274
xref: Wikipedia:Sclera
xref: XAO:0000183
xref: ZFA:0005563
is_a: UBERON:0000064 ! organ part
is_a: UBERON:0010313 ! neural crest-derived structure
relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye
relationship: develops_from UBERON:0003314 {source="ISBN:0781772214"} ! eye mesenchyme
relationship: has_part CL:0000347 {source="ZFA"} ! scleral cell
relationship: has_quality PATO:0000963 ! opaque
relationship: part_of UBERON:0012430 {source="FMA"} ! tunica fibrosa of eyeball
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The sclera, also known as the white part of the eye, is the opaque (usually white, though certain animals, such as horses and lizards, can have black sclera), fibrous, protective, outer layer of the eye containing collagen and elastic fiber. It is derived from the neural crest. In children, it is thinner and shows some of the underlying pigment, appearing slightly blue. In the elderly, however, fatty deposits on the sclera can make it appear slightly yellow. The sclera forms the posterior five sixths of the connective tissue coat of the globe. It is continuous with the dura mater and the cornea, and maintains the shape of the globe, offering resistance to internal and external forces, and provides an attachment for the extraocular muscle insertions. The sclera is perforated by plenty of nerves and vessels passing through the posterior scleral foramen, the hole that is formed by the optic nerve. At the optic disk the outer two-thirds of the sclera continues with the dura mater (outer coat of the brain) via the dural sheath of the optic nerve. The inner third joins with some choroidal tissue to form a plate (lamina cribrosa) across the optic nerve with perforations through which the optic fibers (fasciculi). The thickness of the sclera varies from 1mm at the posterior pole to 0.3 mm just behind the rectus muscle insertions. The sclera's blood vessels are mainly on the surface, and together with the conjunctiva (which lies on top) This is a thin layer covering the sclera. Along with the vessels of the conjunctiva, those of the sclera renders the inflamed eye bright red. [WP,unvetted][Wikipedia:Sclera]." xsd:string {source="Wikipedia:Sclera"}
property_value: UBPROP:0000001 "The tough, usually white, outer coat of the eyeball, covering all the posterior surface and continuous anteriorly with the cornea. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001274", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/sclera"}
property_value: UBPROP:0000007 "scleral" xsd:string
property_value: UBPROP:0000008 "in fish, reptiles and monotremes the connective tissue of the sclera is skeletal" xsd:string
property_value: UBPROP:0000010 "continuous with the dura mater and the cornea; The sclera forms the posterior five-sixths of the connective tissue coat of the globe." xsd:string
property_value: UBPROP:0000011 "Majority derives from NC that surrounds optic cup of neurectoderm; a small temporal portion develops from the mesoderm that contributes to striated extra-ocular muscles and vascular endothelia[Rada&Johnson]." xsd:string
property_value: UBPROP:0000011 "Seko et al demonstrate chondrogenic potential and identify this as connective tissue[DOI:10.1371/journal.pone.0003709]." xsd:string

[Term]
id: UBERON:0001774
name: skeletal muscle of trunk
namespace: uberon
def: "A skeletal muscle organ that is part of the trunk region." [http://orcid.org/0000-0002-6601-2165]
subset: uberon_slim
subset: vertebrate_core
synonym: "body musculature" EXACT [ZFA:0000473]
synonym: "muscle of trunk" EXACT [FMA:58274]
synonym: "muscle organ of torso" EXACT [OBOL:automatic]
synonym: "muscle organ of trunk" EXACT [OBOL:automatic]
synonym: "torso muscle organ" EXACT [OBOL:automatic]
synonym: "trunk muscle" EXACT []
synonym: "trunk muscle organ" EXACT [OBOL:automatic]
synonym: "trunk musculature" EXACT []
xref: AAO:0000611
xref: EMAPA:35888
xref: FMA:58274
xref: MA:0000514
xref: TAO:0000473
xref: XAO:0003230
xref: ZFA:0000473
is_a: UBERON:0005177 ! trunk region element
is_a: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0004479 {source="prolog"} ! musculature of trunk
property_value: editor_note "Note that this class excludes smooth muscle elements in the trunk region, such as the internal anal sphincter. This appears to be consistent with other ontologies such as FMA and ZFA which appear to only include skeletal muscles here. In fact the MA class 'trunk muscle' is classified as a 'set of skeletal muscles'." xsd:string
property_value: UBPROP:0000012 "Many ontologies do not appear to have a coherent distinction between an individual muscle and the musculature (i.e. the set of muscles in a region), so we group all together here." xsd:string

[Term]
id: UBERON:0001775
name: ciliary body
namespace: uberon
def: "The thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes." [ISBN:0-683-40008-8, MP:0005099, Wikipedia:Ciliary_body]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "anterior uvea" RELATED []
synonym: "ciliary bodies" RELATED OMO:0003004 [VHOG:0000102]
synonym: "corpus ciliare" RELATED OMO:0003011 [Wikipedia:Ciliary_body]
synonym: "ocular ciliary body" EXACT []
xref: AAO:0010341
xref: BTO:0000260
xref: CALOHA:TS-0694
xref: EMAPA:19065
xref: EV:0100346
xref: FMA:58295
xref: GAID:916
xref: MA:0000264
xref: MESH:D002924
xref: NCIT:C12345
xref: neuronames:1571
xref: SCTID:263340007
xref: UMLS:C0008779 {source="ncithesaurus:Ciliary_Body"}
xref: VHOG:0000102
xref: Wikipedia:Ciliary_body
xref: XAO:0000186
is_a: UBERON:0000481 ! multi-tissue structure
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: contributes_to_morphology_of UBERON:0011892 ! anterior uvea
relationship: develops_from UBERON:0002346 {source="ISBN:0781772214"} ! neurectoderm
relationship: has_part UBERON:0001605 ! ciliary muscle
relationship: has_part UBERON:0010427 ! ciliary processes
relationship: part_of UBERON:0011892 ! anterior uvea
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000102", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001776
name: optic choroid
namespace: uberon
def: "Vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]." [Wikipedia:Choroid]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "chorioid" RELATED [BTO:0001829]
synonym: "choroid" EXACT [MA:0000263]
synonym: "choroid coat" EXACT [Wikipedia:Choroid]
synonym: "choroidea" EXACT [Wikipedia:Choroid]
synonym: "choroidea" RELATED OMO:0003011 [Wikipedia:Choroid]
synonym: "eye choroid" EXACT [VHOG:0001568]
synonym: "optic choroid" RELATED [ZFA:0005229]
synonym: "posterior uvea" EXACT [Wikipedia:Uvea#Regions]
xref: BTO:0001829
xref: CALOHA:TS-2054
xref: EMAPA:19077
xref: EV:0100347
xref: FMA:58298
xref: GAID:913
xref: MA:0000263
xref: MESH:D002829
xref: NCIT:C12344
xref: SCTID:181172003
xref: TAO:0005229
xref: UMLS:C0008520 {source="ncithesaurus:Choroid"}
xref: VHOG:0001568
xref: Wikipedia:Choroid
xref: ZFA:0005229
is_a: UBERON:0002203 ! vasculature of eye
disjoint_from: UBERON:0011892 {source="lexical"} ! anterior uvea
relationship: adjacent_to UBERON:0000966 ! retina
relationship: adjacent_to UBERON:0001773 ! sclera
relationship: adjacent_to UBERON:0011892 ! anterior uvea
relationship: contributes_to_morphology_of UBERON:0001768 ! uvea
relationship: overlaps UBERON:0001802 {source="Wikipedia"} ! posterior segment of eyeball
relationship: part_of UBERON:0001768 {source="MA"} ! uvea
relationship: part_of UBERON:0019207 ! chorioretinal region
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI
property_value: editor_note "check choroid vs choroid layer; check ZFA/TAO placement - no homology assertion in VHOG. Note this is entirely in the posterior region of eyeball in ZFA" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000007 "choroidal" xsd:string
property_value: UBPROP:0000012 "MP treats posterior uvea and optic choroid as distinct" xsd:string {external_ontology="MP"}

[Term]
id: UBERON:0001777
name: substantia propria of cornea
namespace: uberon
def: "The lamellated connective tissue of the cornea between the Bowman and Descemet membranes." [ISBN:0-683-40008-8, MESH:A09.371.060.217.228, MP:0005300]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "corneal stroma" EXACT [MA:0001245]
synonym: "stroma of cornea" EXACT []
synonym: "substantia propria" BROAD []
synonym: "substantia propria corneae" EXACT OMO:0003011 [FMA:58306, FMA:TA]
xref: CALOHA:TS-1138
xref: EFO:0002514
xref: EMAPA:17602
xref: FMA:58306
xref: GAID:893
xref: MA:0001245
xref: MESH:D003319
xref: NCIT:C12699
xref: SCTID:362511000
xref: TAO:0002189
xref: UMLS:C0010040 {source="ncithesaurus:Corneal_Stroma"}
xref: Wikipedia:Corneal_stroma
xref: ZFA:0001685
is_a: UBERON:0003891 ! stroma
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0003891 ! stroma
intersection_of: part_of UBERON:0000964 ! cornea
relationship: adjacent_to UBERON:0004367 ! Descemet's membrane
relationship: adjacent_to UBERON:0004370 ! anterior limiting lamina of cornea
relationship: contributes_to_morphology_of UBERON:0000964 ! cornea
relationship: develops_from UBERON:0007213 {inferred_by="cjm", source="ISBN:0781772214", source="Wikipedia"} ! mesenchyme derived from head neural crest
relationship: part_of UBERON:0000964 ! cornea
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png" xsd:anyURI
property_value: UBPROP:0000001 "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002189", ontology="TAO", source="ZFIN:ZDB-PUB-061010-3"}
property_value: UBPROP:0000002 "relationship type change: subclass tissue (CARO:0000043) CHANGED TO: develops_from tissue (UBERON:0000479)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002189", ontology="TAO"}
property_value: UBPROP:0000002 "relationship type change: subclass tissue (CARO:0000043) CHANGED TO: has_developmental_contribution_from tissue (UBERON:0000479)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002189", ontology="TAO"}

[Term]
id: UBERON:0001778
name: ciliary epithelium
namespace: uberon
def: "A double layer covering the ciliary body that produces aqueous humor." [Wikipedia:Ciliary_body#Ciliary_epithelium]
subset: human_reference_atlas
synonym: "ciliary body epithelium" EXACT [FMA:58464]
synonym: "epithelium of ciliary body" EXACT [FMA:58464]
synonym: "ocular ciliary epithelium" EXACT []
xref: BTO:0001770
xref: CALOHA:TS-0695
xref: EMAPA:35239
xref: FMA:58464
xref: MA:0001238
xref: NCIT:C32314
xref: SCTID:280870004
xref: UMLS:C0459736 {source="ncithesaurus:Ciliary_Epithelium"}
xref: Wikipedia:Ciliary_body#Ciliary_epithelium
is_a: UBERON:0000488 {source="FMA"} ! atypical epithelium
is_a: UBERON:0015808 ! eye epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001775 ! ciliary body
relationship: has_part GO:0048770 {source="MP"} ! pigment granule
relationship: part_of UBERON:0001775 {source="MA"} ! ciliary body
relationship: produces UBERON:0001796 {source="Wikipedia"} ! aqueous humor of eyeball
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001779
name: iris stroma
namespace: uberon
def: "The delicate vascular connective tissue that lies between the anterior surface of the iris and the pars iridica retinae." [http://www.drugs.com/dict/stroma-of-iris.html, Wikipedia:Iris_stroma]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "iridial stroma" EXACT []
synonym: "stroma of iris" EXACT []
xref: EMAPA:35451
xref: FMA:58526
xref: MA:0002777
xref: SCTID:280882008
xref: Wikipedia:Iris_stroma
xref: ZFA:0005569
is_a: UBERON:0003891 ! stroma
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0003891 ! stroma
intersection_of: part_of UBERON:0001769 ! iris
relationship: contributes_to_morphology_of UBERON:0001769 ! iris
relationship: part_of UBERON:0001769 ! iris
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png" xsd:anyURI

[Term]
id: UBERON:0001780
name: spinal nerve
namespace: uberon
def: "The any of the paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment[MP,modified]." [MESH:A08.800.800.720, MP:0001077]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "backbone nerve" EXACT [OBOL:automatic]
synonym: "nerve of backbone" EXACT [OBOL:automatic]
synonym: "nerve of spinal column" EXACT [OBOL:automatic]
synonym: "nerve of spine" EXACT [OBOL:automatic]
synonym: "nerve of vertebral column" EXACT [OBOL:automatic]
synonym: "nervi spinales" RELATED OMO:0003011 [Wikipedia:Spinal_nerve]
synonym: "spinal column nerve" EXACT [OBOL:automatic]
synonym: "spinal nerve tree" EXACT []
synonym: "spinal nerves" RELATED OMO:0003004 [BAMS:spin]
synonym: "spine nerve" EXACT [OBOL:automatic]
synonym: "vertebral column nerve" EXACT [OBOL:automatic]
xref: AAO:0011101
xref: BAMS:spin
xref: BTO:0000870
xref: EHDAA2:0001898
xref: EMAPA:16989
xref: FMA:5858
xref: GAID:841
xref: MA:0000233
xref: MESH:D013127
xref: NCIT:C12792
xref: neuronames:1228
xref: SCTID:361099009
xref: UMLS:C0037941 {source="ncithesaurus:Spinal_Nerve"}
xref: VHOG:0000824
xref: Wikipedia:Spinal_nerve
xref: XAO:0003101
is_a: UBERON:0001021 ! nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: extends_fibers_into UBERON:0002240 ! spinal cord
relationship: extends_fibers_into UBERON:0002240 ! spinal cord
relationship: part_of RO:0002577 ! system
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Any of the paired nerves emerging from the spinal cord, each attached to the cord by two roots: ventral and dorsal, and passing out between the vertebrae. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000824", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/spinal+nerve"}

[Term]
id: UBERON:0001781
name: layer of retina
namespace: uberon
def: "Any of the layers that make up the retina[MP]." [MP:0003727]
subset: pheno_slim
subset: vertebrate_core
synonym: "retina layer" EXACT []
synonym: "retina neuronal layer" EXACT [MP:0006069]
synonym: "retinal layer" EXACT []
synonym: "retinal neuronal layer" EXACT [MP:0006069]
xref: AAO:0010353
xref: EMAPA:35742
xref: FMA:58617
xref: MA:0001319
xref: NCIT:C49328
xref: SCTID:280657006
xref: UMLS:C0459649 {source="ncithesaurus:Retina_Layer"}
xref: XAO:0000266
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0022303 ! nervous system cell part layer
relationship: contributes_to_morphology_of UBERON:0000966 ! retina
relationship: part_of UBERON:0000966 ! retina
property_value: UBPROP:0000012 "MA does not treat internal/external limiting memranes as layers - these are classified as laminae. Here we follow other ontologies in grouping with other layers. MA also treats retinal pigment epithelium and neural retina epithelium as distinct from the layers. We follow ontologies such as FMA and ZFA in first dividing into pigmented and neural layers - these are also classified as layers, giving us over the usual 10 layers" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0001785
name: cranial nerve
namespace: uberon
def: "Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord." [Wikipedia:Cranial_nerve]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cranial nerves" RELATED []
synonym: "cranial neural tree organ" EXACT []
synonym: "nervus cranialis" RELATED OMO:0003011 [Wikipedia:Cranial_nerve]
xref: AAO:0000108
xref: BAMS:cran
xref: BIRNLEX:1623
xref: BTO:0001104
xref: EHDAA2:0000323
xref: EMAPA:17264
xref: FMA:5865
xref: GAID:802
xref: HBA:9299
xref: MA:0000215
xref: MBA:967
xref: MESH:D003391
xref: NCIT:C12700
xref: neuronames:1227
xref: SCTID:244447006
xref: TAO:0000641
xref: UMLS:C0010268 {source="BIRNLEX:1623", source="ncithesaurus:Cranial_Nerve"}
xref: UMLS:C1269897 {source="BIRNLEX:1623"}
xref: VHOG:0000279
xref: Wikipedia:Cranial_nerve
xref: XAO:0000429
xref: XAO:0003089
xref: ZFA:0000641
is_a: UBERON:0011779 ! nerve of head region
is_a: UBERON:0034713 ! cranial neuron projection bundle
intersection_of: UBERON:0001021 ! nerve
intersection_of: anterior_to UBERON:0001780 ! spinal nerve
intersection_of: extends_fibers_into UBERON:0000955 ! brain
relationship: anterior_to UBERON:0001780 ! spinal nerve
relationship: has_developmental_contribution_from UBERON:0003099 ! cranial neural crest
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/18/Brain_human_normal_inferior_view_with_labels_en-2.svg" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/84/Brain_human_normal_inferior_view_with_labels_en.svg" xsd:anyURI
property_value: editor_note "classified as neural tree organ, not nerve in FMA. CN II poses a challenge here as it is not strictly a nerve, yet is expected to be classified under CN." xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Twelve pairs of cranial nerves exit/enter the cranium through openings in the skull. The nerves contain efferent axons with motor and glandular functions, as well as afferent axons from cranial ganglia with sensory functions. The nerves are numbered in a rostral to caudal sequence, with the exception of the lateral line nerves.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000641", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000279", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "See https://github.com/obophenotype/mouse-anatomy-ontology/issues/6" xsd:string

[Term]
id: UBERON:0001796
name: aqueous humor of eyeball
namespace: uberon
def: "A thick watery refractive medium that fills the space between the lens and the cornea[WP]." [Wikipedia:Aqueous_humor]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "aqueous humor" EXACT []
synonym: "aqueous humour" EXACT [EHDAA2:0000139]
synonym: "humor aquosus" EXACT OMO:0003011 [FMA:58819, FMA:TA]
xref: EHDAA2:0000139
xref: EHDAA:10196
xref: EMAPA:18232
xref: ENVO:02000024
xref: FMA:58819
xref: GAID:890
xref: MA:0001236
xref: MESH:D001082
xref: NCIT:C13190
xref: SCTID:280587006
xref: UMLS:C0003662 {source="ncithesaurus:Aqueous_Humor"}
xref: VHOG:0000548
xref: Wikipedia:Aqueous_humor
xref: ZFA:0005564
is_a: UBERON:0006312 ! ocular refractive media
is_a: UBERON:0006314 ! bodily fluid
relationship: contributes_to_morphology_of UBERON:0001766 ! anterior chamber of eyeball
relationship: part_of UBERON:0001766 {notes="FMA def states A and P", notes="located_in in EHDAA2", source="VHOG"} ! anterior chamber of eyeball
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI
property_value: UBPROP:0000001 "The fluid produced by the ciliary process in the eye and occupying the anterior and posterior chambers. It provides nourishment for the lens and cornea and maintains the ocular pressure, and hence the optical integrity of the eyeball. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000548", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/aqueous+humour"}
property_value: UBPROP:0000003 "(...) we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya (reference 1); Although the eye varies greatly in adaptative details among vertebrates, its basic structure is the same in all. The human eye is representative of the design typical for a tetrapod. (...) A watery aqueous humor fills the spaces in the eye in front of the lens (...) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000548", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007), ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.424 and p.426 and p.429 and Figure 12-24", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "FMA says A+P chambers, and MA states A chamber. ZFA states A chamber and tha it is produced primarily by dorsal ciliary epithelial cells.To be investigated across taxa." xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001800
name: sensory ganglion
namespace: uberon
def: "The clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells." [MP:0000960]
subset: human_reference_atlas
subset: pheno_slim
synonym: "ganglion sensorium" EXACT OMO:0003011 []
xref: AEO:0001000
xref: BTO:0005630
xref: EMAPA:36596
xref: FMA:5885
xref: MA:0002566
xref: MESH:D017950
xref: NCIT:C13060
xref: UMLS:C0206429 {source="ncithesaurus:Sensory_Ganglion"}
is_a: UBERON:0000045 ! ganglion
intersection_of: UBERON:0000045 ! ganglion
intersection_of: extends_fibers_into UBERON:0001027 ! sensory nerve
relationship: extends_fibers_into UBERON:0001027 ! sensory nerve
relationship: part_of RO:0002577 ! system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001801
name: anterior segment of eyeball
namespace: uberon
def: "Any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive)." [ISBN:0-683-40008-8, MESH:A09.371.060, MP:0005193]
subset: pheno_slim
subset: vertebrate_core
synonym: "anterior eye segment" EXACT []
synonym: "anterior segment eye" EXACT [ZFA:0005566]
synonym: "anterior segment of eye" EXACT []
synonym: "anterior segment of the eye" EXACT []
synonym: "eye anterior segment" EXACT []
synonym: "segmentum anterius (bulbus oculi)" EXACT []
synonym: "segmentum anterius bulbi oculi" RELATED OMO:0003011 [Wikipedia:Anterior_segment_of_eyeball]
xref: EMAPA:36594
xref: FMA:58865
xref: MA:0002484
xref: MESH:D000869
xref: NCIT:C12668
xref: SCTID:280658001
xref: UMLS:C0003153 {source="ncithesaurus:Anterior_Eye_Segment"}
xref: Wikipedia:Anterior_segment_of_eyeball
xref: ZFA:0005566
is_a: UBERON:0000063 ! organ subunit
is_a: UBERON:0004121 ! ectoderm-derived structure
disjoint_from: UBERON:0001802 {source="lexical"} ! posterior segment of eyeball
relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye
relationship: in_anterior_side_of UBERON:0010230 {source="cjm"} ! eyeball of camera-type eye
relationship: part_of UBERON:0010230 {source="FMA"} ! eyeball of camera-type eye
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Cataract_in_human_eye.png" xsd:anyURI
property_value: RO:0002171 UBERON:0001802 {exceptions="ZFA", source="https://github.com/obophenotype/uberon/issues/378", status="pending"}

[Term]
id: UBERON:0001802
name: posterior segment of eyeball
namespace: uberon
def: "Any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive)." [ISBN:0-683-40008-8, MP:0005195]
subset: pheno_slim
subset: vertebrate_core
synonym: "eye posterior segment" EXACT []
synonym: "posterior eye segment" EXACT []
synonym: "posterior segment eye" EXACT [ZFA:0005567]
synonym: "posterior segment of eye" EXACT []
synonym: "posterior segment of the eye" EXACT []
synonym: "segmentum posterius (bulbus oculi)" EXACT []
synonym: "segmentum posterius bulbi oculi" RELATED OMO:0003011 [Wikipedia:Posterior_segment_of_eyeball]
xref: EMAPA:36595
xref: FMA:58868
xref: MA:0002485
xref: NCIT:C12906
xref: SCTID:280659009
xref: UMLS:C0278450 {source="ncithesaurus:Posterior_Eye_Segment"}
xref: Wikipedia:Posterior_segment_of_eyeball
xref: ZFA:0005567
is_a: UBERON:0000063 ! organ subunit
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye
relationship: in_posterior_side_of UBERON:0010230 {source="cjm"} ! eyeball of camera-type eye
relationship: part_of UBERON:0010230 {source="FMA"} ! eyeball of camera-type eye
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI

[Term]
id: UBERON:0001803
name: epithelium of lens
namespace: uberon
def: "A layer of epithelial cells that is part of the eye." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: vertebrate_core
synonym: "epithelial tissue of eye lens" EXACT [OBOL:automatic]
synonym: "epithelial tissue of lens" EXACT [OBOL:automatic]
synonym: "epithelium lentis" EXACT OMO:0003011 [FMA:58871, FMA:TA]
synonym: "epithelium of eye lens" EXACT [OBOL:automatic]
synonym: "eye lens epithelial tissue" EXACT [OBOL:automatic]
synonym: "eye lens epithelium" EXACT [OBOL:automatic]
synonym: "lens epithelial tissue" EXACT [OBOL:automatic]
synonym: "lens epithelium" EXACT []
xref: BTO:0001873
xref: CALOHA:TS-0543
xref: EMAPA:32871
xref: FMA:58871
xref: MA:0001301
xref: SCTID:362523006
xref: TAO:0001326
xref: Wikipedia:Lens_(anatomy)#Lens_Epithelium
xref: XAO:0004094
xref: ZFA:0001326
is_a: UBERON:0000484 ! simple cuboidal epithelium
is_a: UBERON:0015808 ! eye epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000965 ! lens of camera-type eye
relationship: contributes_to_morphology_of UBERON:0000965 ! lens of camera-type eye
relationship: part_of UBERON:0000965 ! lens of camera-type eye
property_value: curator_notes "this class is the superclass of the anterior epithelium and equatorial epithlium, although the term 'lens epithelium' may refer specifically to the former" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001804
name: capsule of lens
namespace: uberon
def: "The elastic, clear, membrane-like structure, that is outer most layer of the lens." [MGI:smb, MP:0003236, PMID:15483628]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "capsula lentis" EXACT OMO:0003011 []
synonym: "lens capsule" EXACT []
xref: EHDAA2:0000977
xref: EMAPA:18237
xref: FMA:58881
xref: MA:0001300
xref: NCIT:C32975
xref: SCTID:244500004
xref: UMLS:C0229232 {source="ncithesaurus:Lens_Capsule"}
xref: VHOG:0000550
xref: Wikipedia:Lens_(anatomy)#Lens_capsule
xref: ZFA:0005574
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005764 ! acellular membrane
intersection_of: UBERON:0000476 ! acellular anatomical structure
intersection_of: bounding_layer_of UBERON:0000965 ! lens of camera-type eye
relationship: bounding_layer_of UBERON:0000965 ! lens of camera-type eye
relationship: develops_from UBERON:0005614 {source="EHDAA2"} ! lens anterior epithelium
relationship: has_part CHEBI:35722 ! sulfated glycosaminoglycan
relationship: has_part GO:0005587 ! collagen type IV trimer
relationship: has_quality PATO:0000964 ! transparent
relationship: part_of UBERON:0000965 ! lens of camera-type eye
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png" xsd:anyURI
property_value: UBPROP:0000001 "The transparent membrane which surrounds the lens of the eye. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000550", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "(...) we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya (reference 1); Although the eye varies greatly in adaptative details among vertebrates, its basic structure is the same in all. The human eye is representative of the design typical for a tetrapod. (...) A watery aqueous humor fills the spaces in the eye in front of the lens (...) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000550", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007), ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.424 and p.426 and p.429 and Figure 12-24", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000010 "synthesized by the lens epithelium and its main components are Type IV collagen and sulfated glycosaminoglycans (GAGs). [Wikipedia:Capsule_of_lens" xsd:string
property_value: UBPROP:0000012 "FMA classifies this is a capsule and hence an organ part. In contrast we classify this as acellular" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001805
name: autonomic ganglion
namespace: uberon
def: "Ganglion that has dendrites that form a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery. There are two subtypes, sympathetic ganglion and parasympathetic ganglion." [Wikipedia:Autonomic_ganglion]
subset: human_reference_atlas
subset: uberon_slim
synonym: "autonomic nervous system ganglion" EXACT [OBOL:automatic]
synonym: "ganglion autonomicum" RELATED OMO:0003011 [Wikipedia:Autonomic_ganglion]
synonym: "ganglion of autonomic nervous system" EXACT [OBOL:automatic]
synonym: "ganglion of visceral nervous system" EXACT [OBOL:automatic]
synonym: "visceral nervous system ganglion" EXACT [OBOL:automatic]
xref: AEO:0001001
xref: CALOHA:TS-2340
xref: EMAPA:17157
xref: EMAPA:18221
xref: FMA:5889
xref: MA:0000220
xref: MESH:D005725
xref: NCIT:C12720
xref: UMLS:C0017068 {source="ncithesaurus:Autonomic_Ganglion"}
xref: Wikipedia:Autonomic_ganglion
is_a: UBERON:0003338 ! ganglion of peripheral nervous system
intersection_of: UBERON:0000045 ! ganglion
intersection_of: part_of UBERON:0002410 ! autonomic nervous system
relationship: extends_fibers_into UBERON:0034728 ! autonomic nerve
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0002410 ! autonomic nervous system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001806
name: sympathetic ganglion
namespace: uberon
def: "A ganglion of the sympathetic nervous system. Examples: paravertebral and the prevertebral ganglia, which include the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia." [http://orcid.org/0000-0002-6601-2165, MP:0001008]
subset: pheno_slim
subset: uberon_slim
synonym: "ganglion of sympathetic nervous system" EXACT [OBOL:automatic]
synonym: "ganglion of sympathetic part of autonomic division of nervous system" EXACT [OBOL:automatic]
synonym: "ganglion sympatheticum" EXACT []
synonym: "ganglion sympathicum" RELATED OMO:0003011 [BTO:0001333, Wikipedia:Sympathetic_ganglion]
synonym: "sympathetic nervous system ganglion" EXACT [OBOL:automatic]
synonym: "sympathetic part of autonomic division of nervous system ganglion" EXACT [OBOL:automatic]
xref: AAO:0010773
xref: BTO:0001333
xref: CALOHA:TS-0994
xref: EHDAA2:0001969
xref: EMAPA:17157
xref: FMA:5890
xref: MA:0000226
xref: MESH:D005728 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C12467
xref: SCTID:362485003
xref: UMLS:C0017071 {source="ncithesaurus:Sympathetic_Ganglion"}
xref: Wikipedia:Sympathetic_ganglion
is_a: UBERON:0001805 ! autonomic ganglion
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0000045 ! ganglion
intersection_of: part_of UBERON:0000013 ! sympathetic nervous system
relationship: contributes_to_morphology_of UBERON:0000013 ! sympathetic nervous system
relationship: develops_from UBERON:0003083 {source="DOI:10.1101/gr.157586.113", source="ISBN:0073040584"} ! trunk neural crest
relationship: extends_fibers_into UBERON:0034729 ! sympathetic nerve
relationship: part_of UBERON:0000013 ! sympathetic nervous system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI

[Term]
id: UBERON:0001833
name: lip
namespace: uberon
def: "One of the two fleshy folds which surround the opening of the mouth." [http://www.medterms.com/script/main/art.asp?articlekey=9458, Wikipedia:Lip]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "labia oris" RELATED OMO:0003011 [Wikipedia:Lip]
synonym: "lips" RELATED []
xref: BTO:0001647
xref: CALOHA:TS-0558
xref: EMAPA:32839
xref: FMA:59816
xref: GAID:76
xref: galen:Lip
xref: MA:0000343
xref: MESH:D008046
xref: NCIT:C12220
xref: SCTID:181221003
xref: TAO:0007006
xref: UMLS:C0023759 {source="ncithesaurus:Lip"}
xref: VHOG:0000677
xref: Wikipedia:Lip
xref: ZFA:0007006
is_a: UBERON:0003102 {source="ZFA"} ! surface structure
relationship: contributes_to_morphology_of UBERON:0000165 ! mouth
relationship: part_of UBERON:0000165 {source="BTO", source="FMA-implicit", source="VHOG", source="ZFA"} ! mouth
relationship: surrounds UBERON:0000166 {source="cjm"} ! oral opening
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/90/Lips.JPG" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/99/Mouth.jpg" xsd:anyURI
property_value: RO:0002161 NCBITaxon:8782
property_value: UBPROP:0000001 "Surface structure that is one of the two fleshy folds surrounding the opening of the mouth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0007006", ontology="TAO", source="ZFIN:curator", source="http//:www.medterms.com/script/main/art.asp?articlekey=9458"}
property_value: UBPROP:0000007 "labial" xsd:string

[Term]
id: UBERON:0001834
name: upper lip
namespace: uberon
alt_id: UBERON:0003391
def: "Lip that covers the upper portion of the mouth.[TAO]." [TAO:0001970, Wikipedia:Upper_lip]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "labium superius oris" RELATED OMO:0003011 [Wikipedia:Upper_lip]
synonym: "upper jaw lip" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: EMAPA:17925
xref: FMA:59817
xref: MA:0000919
xref: SCTID:245776003
xref: TAO:0001970
xref: VHOG:0001750
xref: Wikipedia:Upper_lip
xref: ZFA:0005226
is_a: UBERON:0001833 ! lip
intersection_of: UBERON:0001833 ! lip
intersection_of: part_of UBERON:0001709 ! upper jaw region
relationship: develops_from UBERON:0011592 ! future upper lip
relationship: immediate_transformation_of UBERON:0011592 ! future upper lip
relationship: part_of UBERON:0001709 ! upper jaw region
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg" xsd:anyURI
property_value: UBPROP:0000001 "Lip that covers the lower portion of the mouth. [ZFIN:Curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001750", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000001 "Lip that covers the upper portion of the mouth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001970", ontology="TAO", source="TAO:wd"}

[Term]
id: UBERON:0001835
name: lower lip
namespace: uberon
alt_id: UBERON:0003392
def: "Lip that covers the lower portion of the mouth.[TAO]." [TAO:0002060, Wikipedia:Lower_lip]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "labium inferius oris" RELATED OMO:0003011 [Wikipedia:Lower_lip]
synonym: "lower jaw lip" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: EHDAA2:0001020
xref: EMAPA:17909
xref: FMA:59818
xref: MA:0000921
xref: NCIT:C94572
xref: SCTID:245777007
xref: TAO:0002060
xref: UMLS:C0458583 {source="ncithesaurus:Lower_Lip"}
xref: Wikipedia:Lower_lip
xref: ZFA:0005225
is_a: UBERON:0001833 ! lip
intersection_of: UBERON:0001833 ! lip
intersection_of: part_of UBERON:0001710 ! lower jaw region
relationship: develops_from UBERON:0011596 ! future lower lip
relationship: part_of UBERON:0001710 ! lower jaw region
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/99/Mouth.jpg" xsd:anyURI
property_value: UBPROP:0000001 "Lip that covers the lower portion of the mouth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002060", ontology="TAO", source="TAO:wd"}

[Term]
id: UBERON:0001851
name: cortex
namespace: uberon
def: "Outermost layer of an organ[WP]." [Wikipedia:Cortex_(anatomy)]
subset: pheno_slim
subset: uberon_slim
subset: upper_level
synonym: "cortex" EXACT [FMA:61109]
synonym: "cortex of organ" EXACT []
xref: EFO:0000383
xref: EHDAA:9344
xref: FMA:61109
xref: galen:Cortex
xref: Wikipedia:Cortex_(anatomy)
is_a: UBERON:0000064 ! organ part
relationship: bounding_layer_of UBERON:0000062 ! organ
property_value: UBPROP:0000007 "cortical" xsd:string
property_value: UBPROP:0000012 "this class is used more generically than in FMA, and includes e.g. cortex of hair" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001884
name: phrenic nerve
namespace: uberon
def: "A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium." [VHOG:0000728]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "diaphragmatic nerve" RELATED [BTO:0001063]
synonym: "nervus phrenicus" RELATED OMO:0003011 [BTO:0001063, Wikipedia:Phrenic_nerve]
synonym: "phrenic" RELATED [BTO:0001063]
xref: BAMS:phn
xref: BTO:0001063
xref: EHDAA:4677
xref: EMAPA:17813
xref: FMA:6191
xref: GAID:848
xref: MA:0001170
xref: MESH:D010791
xref: NCIT:C52813
xref: SCTID:280344009
xref: UMLS:C0031774 {source="ncithesaurus:Phrenic_Nerve"}
xref: VHOG:0000728
xref: Wikipedia:Phrenic_nerve
is_a: UBERON:0003443 ! thoracic cavity nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: innervates UBERON:0001103 ! diaphragm
relationship: branching_part_of UBERON:0000962 ! nerve of cervical vertebra
relationship: innervates UBERON:0001103 ! diaphragm
relationship: part_of UBERON:0000962 ! nerve of cervical vertebra
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/3c/Gray806.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000728", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/phrenic+nerve"}

[Term]
id: UBERON:0001891
name: midbrain
namespace: uberon
def: "The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]." [GO:0030901]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "MB" BROAD OMO:0003000 [BIRNLEX:1667, NIFSTD:NeuroNames_abbrevSource]
synonym: "mesencephalon" RELATED OMO:0003011 [Wikipedia:Midbrain]
xref: AAO:0010149
xref: BAMS:MES
xref: BIRNLEX:1667
xref: BM:MB
xref: BTO:0000138
xref: CALOHA:TS-0630
xref: DHBA:10648
xref: DMBA:16649
xref: EFO:0000919
xref: EHDAA2:0001162
xref: EHDAA:3694
xref: EMAPA:16974
xref: EV:0100242
xref: FMA:61993
xref: HBA:9001
xref: MA:0000207
xref: MAT:0000106
xref: MBA:313
xref: MESH:D008636
xref: MIAA:0000106
xref: NCIT:C12510
xref: neuronames:462 {source="BIRNLEX:1667"}
xref: RETIRED_EHDAA2:0001104
xref: SCTID:279099009
xref: TAO:0000128
xref: UMLS:C0025462 {source="BIRNLEX:1667", source="ncithesaurus:Mesencephalon"}
xref: VHOG:0000069
xref: Wikipedia:Midbrain
xref: XAO:0000014
xref: ZFA:0000128
is_a: UBERON:0002616 ! regional part of brain
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
relationship: contributes_to_morphology_of UBERON:0000955 ! brain
relationship: develops_from UBERON:0009616 ! presumptive midbrain
relationship: has_developmental_contribution_from UBERON:0003849 {evidence="definitional"} ! mesencephalic neural crest
relationship: immediate_transformation_of UBERON:0009616 {source="Bgee:AN"} ! presumptive midbrain
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG" xsd:anyURI
property_value: editor_note "developmental relationships need revised" xsd:string
property_value: RO:0002171 UBERON:0001894 {exceptions="ZFA", exceptions_url="https://github.com/obophenotype/uberon/issues/378", source="ABA", status="pending"}
property_value: RO:0002171 UBERON:0002028 {exceptions="ZFA", source="ABA", status="pending"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Middle part of the brain composed of the optic tectum and penducular region.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010149", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The brain region between the forebrain anteriorly and the hindbrain posteriorly, including the tectum dorsally and the midbrain tegmentum ventrally. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000128", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "Fine structural, computerized three-dimensional (3D) mapping of cell connectivity in the amphioxus nervous system and comparative molecular genetic studies of amphioxus and tunicates have provided recent insights into the phylogenetic origin of the vertebrate nervous system. The results suggest that several of the genetic mechanisms for establishing and patterning the vertebrate nervous system already operated in the ancestral chordate and that the nerve cord of the proximate invertebrate ancestor of the vertebrates included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000069", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "mesencephalic" xsd:string
property_value: UBPROP:0000012 "part of brainstem in ABA - we reject this in favor of ISBN:0471888893 which has an implicit overlaps relationships" xsd:string {external_ontology="ABA"}

[Term]
id: UBERON:0001892
name: rhombomere
namespace: uberon
def: "A segment of the developing hindbrain[ZFA]. In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube, within the hindbrain region (a neuromere) in the area that will eventually become the rhombencephalon. The rhombomeres appear as a series of slightly constricted swellings in the neural tube, caudal to the cephalic flexure.[WP]." [Wikipedia:Rhombomere, ZFIN:curator]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "future rhombencephalon" RELATED [MIAA:0000272]
synonym: "hindbrain neuromere" EXACT []
synonym: "hindbrain neuromeres" EXACT OMO:0003004 [DHBA:HNM]
synonym: "hindbrain segment" BROAD [ZFA:0001064]
synonym: "rhombomere" EXACT []
synonym: "rhombomeres" RELATED OMO:0003004 [VHOG:0000672]
synonym: "segment of hindbrain" BROAD [ZFA:0001064]
xref: DHBA:12664
xref: EFO:0003617
xref: EMAPA:16148
xref: FMA:295666
xref: MAT:0000272
xref: MIAA:0000272
xref: RETIRED_EHDAA2:0000669
xref: TAO:0001064
xref: VHOG:0000672
xref: Wikipedia:Rhombomere
xref: XAO:0004079
xref: ZFA:0001064
is_a: UBERON:0004731 ! neuromere
intersection_of: UBERON:0004731 ! neuromere
intersection_of: part_of UBERON:0007277 ! presumptive hindbrain
relationship: part_of UBERON:0007277 ! presumptive hindbrain
property_value: UBPROP:0000001 "A segment of the developing hindbrain. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001064", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "Rhombomeric segmentation is found in all living vertebrates and is of fundamental importance to the development of the vertebrate head.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000672", ontology="VHOG", source="DOI:10.1006/dbio.2002.0831 Mazet F, Shimeld SM, The Evolution of Chordate Neural Segmentation. Developmental Biology (2002)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "In human embryonic development, the rhombomeres are present by day 29" xsd:string
property_value: UBPROP:0000012 "DHBA divides this into A(1-3),B(4),C(5-7) and D(8)" xsd:string

[Term]
id: UBERON:0001895
name: metencephalon
namespace: uberon
def: "Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Metencephalon]
comment: the terms metencephalon and myelencephalon are only meaningful in mammals and birds[Neuroanatomy of the Zebrafish Brain]. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata and thus these are not distinguished in ZFA[ZFA].
subset: pheno_slim
subset: uberon_slim
synonym: "epencephalon" BROAD INCONSISTENT [ncithesaurus:Epencephalon]
synonym: "epencephalon-2" EXACT [FMA:62003]
xref: BAMS:Met
xref: BIRNLEX:965
xref: BTO:0000673
xref: CALOHA:TS-2029
xref: DHBA:10655
xref: EHDAA2:0001149
xref: EHDAA:5498
xref: EMAPA:17071
xref: FMA:62003
xref: GAID:594
xref: HBA:4833
xref: MA:0000197
xref: MESH:D020540
xref: NCIT:C32741
xref: neuronames:543 {source="BIRNLEX:965"}
xref: UMLS:C0376353 {source="BIRNLEX:965"}
xref: UMLS:C1516904 {source="ncithesaurus:Epencephalon"}
xref: VHOG:0000741
xref: Wikipedia:Metencephalon
is_a: UBERON:0004733 ! segmental subdivision of hindbrain
relationship: contributes_to_morphology_of UBERON:0002028 ! hindbrain
relationship: develops_from UBERON:0010092 ! future metencephalon
relationship: immediate_transformation_of UBERON:0010092 {evidence="definitional"} ! future metencephalon
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg" xsd:anyURI
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: RO:0002174 NCBITaxon:7955
property_value: UBPROP:0000001 "Anterior part of the hindbrain ventral to the cerebellum[BIRNLEX:965]." xsd:string {source="BIRNLEX:965"}
property_value: UBPROP:0000001 "The anterior of two brain vesicles formed by specialization of the rhombencephalon in the developing embryo. It gives rise to cerebellum and pons. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000741", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/metencephalon"}
property_value: UBPROP:0000003 "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000741", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) p.381-382, ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001896
name: medulla oblongata
namespace: uberon
def: "Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]." [FMA:62004, GO:0021550, Wikipedia:Bone_marrow_of_ovary_oblongata]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "bulb" BROAD []
synonym: "bulbus" EXACT OMO:0003011 [FMA:62004, FMA:TA]
synonym: "medulla" BROAD [ABA:MY]
synonym: "medulla oblonzata" RELATED OMO:0003011 [Wikipedia:Medulla_oblongata]
synonym: "metepencephalon" RELATED [FMA:62004]
xref: AAO:0010486
xref: BAMS:Md
xref: BAMS:MY
xref: BIRNLEX:957
xref: BM:Me
xref: BTO:0000041
xref: CALOHA:TS-0607
xref: DMBA:17352
xref: EFO:0000924
xref: EHDAA2:0001088
xref: EHDAA:7588
xref: EMAPA:17550
xref: EV:0100275
xref: FMA:62004
xref: GAID:590
xref: MA:0000206
xref: MAT:0000111
xref: MAT:0000367
xref: MBA:354
xref: MESH:D008526
xref: MIAA:0000111
xref: NCIT:C12442
xref: neuronames:698 {source="BIRNLEX:957"}
xref: SCTID:279104005
xref: TAO:0000545
xref: UMLS:C0025148 {source="ncithesaurus:Medulla_Oblongata", source="BIRNLEX:957"}
xref: UMLS:C1269575 {source="BIRNLEX:957"}
xref: VHOG:0000181
xref: Wikipedia:Bone_marrow_of_ovary_oblongata
xref: XAO:0003100
xref: ZFA:0000545
is_a: UBERON:0000064 ! organ part
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: capable_of GO:0002027 ! regulation of heart rate
relationship: capable_of GO:0043576 ! regulation of respiratory gaseous exchange
relationship: capable_of GO:0044058 ! regulation of digestive system process
relationship: part_of UBERON:0002298 ! brainstem
relationship: part_of UBERON:0005290 ! myelencephalon
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6b/Illu_pituitary_pineal_glands.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Posterior portion of the hindbrain which controls respiration, heartbeat, digestion, and swallowing as well as some locomotor responses.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010486", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The posterior region of the brain that is continuous with the spinal cord. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-17, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000181", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "Classical anatomical studies subdivided the vertebrate rhombencephalon into pons and medulla oblongata. (...) The medulla oblongata appears therefore as a tagma, that is, a group of segmental units (pseudorhombomeres, in this case) sharing some morphological and molecular characteristics, and in some aspects different from the segmental units present in adjoining brain regions, pons and spinal cord.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000181", ontology="VHOG", source="DOI:10.1016/j.ydbio.2008.08.017 Marin F, Aroca P, Puelles L, Hox gene colinear expression in the avian medulla oblongata is correlated with pseudorhombomeric domains. Developmental Biology (2008)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001902
name: epithelium of small intestine
namespace: uberon
def: "An epithelium that is part of a small intestine [Automatically generated definition]." [OBOL:automatic]
subset: vertebrate_core
synonym: "epithelial tissue of small bowel" EXACT [OBOL:automatic]
synonym: "epithelial tissue of small intestine" EXACT [OBOL:automatic]
synonym: "epithelium of small bowel" EXACT [OBOL:automatic]
synonym: "mid intestine epithelium" EXACT [ZFA:0005127]
synonym: "small bowel epithelial tissue" EXACT [OBOL:automatic]
synonym: "small bowel epithelium" EXACT [OBOL:automatic]
synonym: "small intestinal epithelium" EXACT []
synonym: "small intestine epithelial tissue" EXACT [OBOL:automatic]
synonym: "small intestine epithelium" EXACT []
xref: BTO:0001258
xref: CALOHA:TS-2104
xref: EMAPA:35778
xref: FMA:62017
xref: MA:0001553
xref: SCTID:45480009
xref: TAO:0005127
xref: ZFA:0005127
is_a: UBERON:0001277 ! intestinal epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: has_part CL:0000164 {source="FMA"} ! enteroendocrine cell
relationship: part_of UBERON:0001204 ! mucosa of small intestine
property_value: UBPROP:0000001 "Intestinal epithelium which lines the lumen of the mid intestine.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005127", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0001915
name: endothelium of capillary
namespace: uberon
def: "An endothelium that is part of a capillary [Automatically generated definition]." [OBOL:automatic]
synonym: "blood capillary endothelium" EXACT [OBOL:automatic]
synonym: "capillary endothelium" EXACT []
synonym: "capillary vessel endothelium" EXACT [OBOL:automatic]
synonym: "endothelium of blood capillary" EXACT [OBOL:automatic]
synonym: "endothelium of capillary vessel" EXACT [OBOL:automatic]
xref: BTO:0004954
xref: CALOHA:TS-0112
xref: EMAPA:36292
xref: FMA:62114
xref: MA:0000711
xref: NCIT:C49215
xref: UMLS:C0006904 {source="ncithesaurus:Capillary_Endothelium"}
is_a: UBERON:0008339 ! microvascular endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0001982 ! capillary
relationship: part_of UBERON:0001982 ! capillary

[Term]
id: UBERON:0001916
name: endothelium of arteriole
namespace: uberon
def: "An endothelium that is part of an arteriole [Automatically generated definition]." [OBOL:automatic]
synonym: "arteriole endothelium" EXACT []
xref: EMAPA:36286
xref: FMA:62115
xref: MA:0000705
xref: NCIT:C49192
xref: UMLS:C1179024 {source="ncithesaurus:Arteriole_Endothelium"}
is_a: UBERON:0004700 ! arterial system endothelium
is_a: UBERON:0008339 ! microvascular endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0001980 ! arteriole
relationship: part_of UBERON:0001980 ! arteriole

[Term]
id: UBERON:0001917
name: endothelium of artery
namespace: uberon
def: "An endothelium that is part of an artery [Automatically generated definition]." [OBOL:automatic]
synonym: "arterial endothelium" EXACT []
synonym: "artery endothelium" EXACT []
xref: AAO:0011013
xref: BTO:0004757
xref: EMAPA:35148
xref: FMA:62116
xref: MA:0000707
xref: NCIT:C49194
xref: UMLS:C1179025 {source="ncithesaurus:Artery_Endothelium"}
xref: VHOG:0001215
xref: XAO:0000357
is_a: UBERON:0003915 ! endothelial tube
is_a: UBERON:0004638 ! blood vessel endothelium
is_a: UBERON:0004700 ! arterial system endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0001637 ! artery
relationship: part_of UBERON:0001637 ! artery
property_value: UBPROP:0000001 "The endothelium is the thin layer of cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011013", ontology="AAO", source="XAO:curator"}
property_value: UBPROP:0000003 "Vertebrates and a very few invertebrates such as squids have evolved a secondary epithelium, the endothelium, that lines their blood vessels.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001215", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.207", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001918
name: endothelium of venule
namespace: uberon
def: "An endothelium that is part of a venule [Automatically generated definition]." [OBOL:automatic]
synonym: "venule endothelium" EXACT []
xref: EMAPA:36290
xref: FMA:62117
xref: MA:0000716
xref: NCIT:C49319
xref: UMLS:C1179026 {source="ncithesaurus:Venule_Endothelium"}
is_a: UBERON:0004701 ! venous system endothelium
is_a: UBERON:0008339 ! microvascular endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0001979 ! venule
relationship: part_of UBERON:0001979 ! venule

[Term]
id: UBERON:0001919
name: endothelium of vein
namespace: uberon
def: "An endothelium that is part of a vein [Automatically generated definition]." [OBOL:automatic]
synonym: "vein endothelium" EXACT []
synonym: "veinous endothelium" RELATED [VHOG:0001216]
synonym: "venous endothelium" EXACT []
xref: AAO:0011110
xref: BTO:0004756
xref: EMAPA:36288
xref: FMA:62118
xref: MA:0000712
xref: NCIT:C49317
xref: UMLS:C1179027 {source="ncithesaurus:Vein_Endothelium"}
xref: VHOG:0001216
xref: XAO:0000358
is_a: UBERON:0004638 ! blood vessel endothelium
is_a: UBERON:0004701 ! venous system endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0001638 ! vein
relationship: part_of UBERON:0001638 ! vein
property_value: UBPROP:0000003 "Vertebrates and a very few invertebrates such as squids have evolved a secondary epithelium, the endothelium, that lines their blood vessels.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001216", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.207", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001943
name: midbrain tegmentum
namespace: uberon
def: "Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]." [FMA:FMA, ISBN:0471888893, Wikipedia:Midbrain_tegmentum]
comment: 'tegmentum' is used generically for the ventral part of the brainstem (ISBN:0471888893). We use the label 'midbrain tegmentum' to denote the midbrain structure. In NIFSTD tegmentum is a composite structure and there is a separate class for midbrain tegmentum and pontine tegmentum
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "mesencephalic tegmentum" RELATED [VHOG:0001367]
synonym: "MTg" BROAD OMO:0003000 [BIRNLEX:1200, NIFSTD:NeuroNames_abbrevSource]
synonym: "tegmentum" BROAD [ISBN:0471888893]
synonym: "tegmentum mesencephali" EXACT OMO:0003011 [Wikipedia:Midbrain_tegmentum]
synonym: "tegmentum mesencephalicum" RELATED OMO:0003011 [NeuroNames:491]
synonym: "tegmentum of midbrain" EXACT []
xref: BAMS:MTg
xref: BIRNLEX:1200
xref: BTO:0003388
xref: DHBA:12195
xref: EFO:0000921
xref: EHDAA2:0004475
xref: EMAPA:18215
xref: FMA:62393
xref: HBA:9002
xref: MA:0000212
xref: MAT:0000452
xref: MESH:D013681 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: neuronames:491 {source="BIRNLEX:1200"}
xref: SCTID:362392007
xref: TAO:0000160
xref: UMLS:C0039441 {source="BIRNLEX:1200"}
xref: VHOG:0001367
xref: Wikipedia:Midbrain_tegmentum
xref: XAO:0004271
xref: ZFA:0000160
is_a: UBERON:0002616 ! regional part of brain
relationship: develops_from UBERON:0010285 {source="ZFA"} ! midbrain basal plate
relationship: part_of UBERON:0001891 ! midbrain
relationship: part_of UBERON:0002298 ! brainstem
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "Together, our results reveal a shared basic organization in the tegmental domains of the diencephalon and midbrain of developing lamprey, indicating early appearance of the domain in vertebrate phylogeny.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001367", ontology="VHOG", source="DOI:10.1016/j.brainresbull.2005.05.001 Villar-Cheda B, Abalo XM, Anadon R, Rodicio MC, The tegmental proliferation region in the sea lamprey. Brain Research Bulletin (2005)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0001948
name: regional part of spinal cord
namespace: uberon
def: "A multi-tissue structure that is part of a spinal cord." [OBOL:automatic]
subset: non_informative
synonym: "spinal cord part" RELATED []
xref: BIRNLEX:1496
xref: NCIT:C33969
xref: SCTID:244437008
xref: UMLS:C1268166 {source="ncithesaurus:Spinal_Cord_Part"}
is_a: UBERON:0000073 ! regional part of nervous system
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000481 ! multi-tissue structure
intersection_of: part_of UBERON:0002240 ! spinal cord
relationship: part_of UBERON:0002240 ! spinal cord

[Term]
id: UBERON:0001968
name: semen
namespace: uberon
def: "Organism substance that is composed of sperm cells suspended in seminal fluid." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: uberon_slim
synonym: "ejaculate" RELATED []
synonym: "sperm" RELATED [BTO:0001230]
xref: BTO:0001230
xref: CALOHA:TS-0917
xref: EMAPA:31488
xref: FMA:62966
xref: GAID:1169
xref: MA:0002522
xref: MESH:D012661
xref: NCIT:C13277
xref: NCIT:C13713
xref: UMLS:C1518159 {source="ncithesaurus:Male_Genital_System_Fluid_or_Secretion"}
xref: UMLS:C2756969 {source="ncithesaurus:Semen"}
xref: Wikipedia:Semen
is_a: UBERON:0000463 ! organism substance
relationship: has_part CL:0000019 ! sperm
relationship: has_part UBERON:0006530 ! seminal fluid
relationship: output_of GO:0042713 ! sperm ejaculation
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/40/Human_semen_in_petri_dish2.jpg" xsd:anyURI
property_value: UBPROP:0000007 "seminal" xsd:string
property_value: UBPROP:0000008 "Note that in this ontology, semen is defined as the sum of sperm and seminal fluid, where seminal fluid is defined in taxonomically generic way (see comments for UBERON:0006530)." xsd:string

[Term]
id: UBERON:0001969
name: blood plasma
namespace: uberon
def: "The liquid component of blood, in which erythrocytes are suspended." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "blood plasm" EXACT []
synonym: "plasma" BROAD [MA:0002501]
synonym: "portion of blood plasma" EXACT []
synonym: "portion of plasma" BROAD [FMA:62970]
xref: BTO:0000131
xref: CALOHA:TS-0800
xref: EFO:0001905
xref: EMAPA:35690
xref: FMA:62970
xref: GAID:1178
xref: MA:0002501
xref: MAT:0000052
xref: MESH:D010949
xref: MIAA:0000052
xref: NCIT:C13356
xref: UMLS:C0032105 {source="ncithesaurus:Plasma"}
xref: Wikipedia:Blood_plasma
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000179 ! haemolymphatic fluid
intersection_of: UBERON:0000463 ! organism substance
intersection_of: has_part GO:0005577 ! fibrinogen complex
intersection_of: has_quality PATO:0001548 ! quality of a liquid
intersection_of: part_of UBERON:0000178 ! blood
intersection_of: surrounds CL:0000232 ! erythrocyte
relationship: has_part GO:0005577 ! fibrinogen complex
relationship: part_of UBERON:0000178 ! blood
relationship: surrounds CL:0000232 ! erythrocyte

[Term]
id: UBERON:0001970
name: bile
namespace: uberon
def: "Vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium." [DOI:10.1002/cphy.c120027, Wikipedia:Bile]
subset: pheno_slim
subset: uberon_slim
synonym: "fel" RELATED [BTO:0000121]
synonym: "gall" RELATED [BTO:0000121]
xref: BTO:0000121
xref: CALOHA:TS-1172
xref: ENVO:02000023
xref: FMA:62971
xref: GAID:1157
xref: galen:Bile
xref: MA:0002513
xref: MESH:D001646
xref: NCIT:C13192
xref: UMLS:C0005388 {source="ncithesaurus:Bile"}
xref: Wikipedia:Bile
xref: ZFA:0005857
is_a: UBERON:0000456 ! secretion of exocrine gland
is_a: UBERON:0006314 ! bodily fluid
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: produced_by UBERON:0002107 ! liver
relationship: capable_of_part_of GO:0007586 ! digestion
relationship: has_part CHEBI:16990 {composition="0.3% in humans"} ! bilirubin IXalpha
relationship: has_part CHEBI:22868 ! bile salt
relationship: has_part CHEBI:36277 ! bile acid salt
relationship: has_quality PATO:0001735 ! liquid configuration
relationship: produced_by UBERON:0002107 ! liver
property_value: UBPROP:0000008 "In many species, bile is stored in the gallbladder and upon eating is discharged into the duodenum." xsd:string
property_value: UBPROP:0000009 "aids the process of digestion of lipids in the small intestine" xsd:string
property_value: UBPROP:0000009 "bile salts function to emulsify dietary fats and facilitate their intestinal absorption" xsd:string
property_value: UBPROP:0000009 "elimination of cholesterol" xsd:string
property_value: UBPROP:0000009 "major excretory route for potentially harmful exogenous lipophilic substances" xsd:string
property_value: UBPROP:0000009 "many hormones and pheromones are excreted in bile, and contribute to growth and development of the intestine in some species and provide attractants for the weaning of non-human vertebrates" xsd:string
property_value: UBPROP:0000009 "protects the organism from enteric infections by excreting immune globulin A (IgA), inflammatory cytokines, and stimulating the innate immune system in the intestine" xsd:string

[Term]
id: UBERON:0001971
name: gastric juice
namespace: uberon
subset: pheno_slim
subset: uberon_slim
synonym: "stomach secretion" EXACT []
synonym: "succus gastricus" RELATED [BTO:0000501]
xref: BTO:0000501
xref: FMA:62972
xref: GAID:1160
xref: galen:GastricJuice
xref: MA:0002519
xref: MESH:D005750
xref: NCIT:C32661
xref: UMLS:C0017133 {source="ncithesaurus:Gastric_Secretion"}
xref: Wikipedia:Gastric_juice
is_a: UBERON:0000456 ! secretion of exocrine gland
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: produced_by UBERON:0011953 ! stomach glandular region
relationship: produced_by UBERON:0011953 ! stomach glandular region

[Term]
id: UBERON:0001972
name: submucosa of esophagus
namespace: uberon
def: "A submucosa that is part of a esophagus [Automatically generated definition]." [OBOL:automatic]
synonym: "esophageal submucosa" EXACT []
synonym: "esophagus submucosa" EXACT []
synonym: "gullet submucosa" EXACT [OBOL:automatic]
synonym: "oesophagus submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of esophagus" EXACT []
synonym: "submucosa of gullet" EXACT [OBOL:automatic]
synonym: "submucosa of oesophagus" EXACT [OBOL:automatic]
synonym: "submucous layer of esophagus" RELATED [BTO:0002109]
synonym: "tela submucosa (oesophagus)" EXACT OMO:0003011 [FMA:62997, FMA:TA]
synonym: "tela submucosa esophagi" EXACT OMO:0003011 [BTO:0002109]
synonym: "tela submucosa oesophageae" EXACT OMO:0003011 [FMA:62997, FMA:TA]
synonym: "tela submucosa oesophagi" RELATED [BTO:0002109]
synonym: "tela submucosa of esophagus" EXACT []
xref: BTO:0002109
xref: EMAPA:35325
xref: FMA:62997
xref: MA:0002724
xref: SCTID:362128009
is_a: UBERON:0018257 ! submucosa of digestive tract
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001096 ! wall of esophagus

[Term]
id: UBERON:0001974
name: lamina propria of esophagus
namespace: uberon
def: "A lamina propria that is part of a esophagus [Automatically generated definition]." [OBOL:automatic]
synonym: "esophageal lamina propria" RELATED [EMAPA:26987]
synonym: "esophagus lamina propria" EXACT []
synonym: "esophagus lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "esophagus lamina propria mucosae" EXACT [OBOL:automatic]
synonym: "gullet lamina propria" EXACT [OBOL:automatic]
synonym: "gullet lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "gullet lamina propria mucosae" EXACT [OBOL:automatic]
synonym: "lamina propria mucosa of esophagus" EXACT [OBOL:automatic]
synonym: "lamina propria mucosa of gullet" EXACT [OBOL:automatic]
synonym: "lamina propria mucosa of oesophagus" EXACT [OBOL:automatic]
synonym: "lamina propria mucosae of esophagus" EXACT []
synonym: "lamina propria mucosae of gullet" EXACT [OBOL:automatic]
synonym: "lamina propria mucosae of oesophagus" EXACT [OBOL:automatic]
synonym: "lamina propria of gullet" EXACT [OBOL:automatic]
synonym: "lamina propria of oesophagus" EXACT [OBOL:automatic]
synonym: "oesophagus lamina propria" RELATED []
synonym: "oesophagus lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "oesophagus lamina propria mucosae" EXACT [OBOL:automatic]
xref: EMAPA:26987
xref: FMA:63050
xref: MA:0001568
xref: NCIT:C49223
xref: UMLS:C1707949 {source="ncithesaurus:Esophageal_Lamina_Propria"}
is_a: UBERON:0000030 ! lamina propria
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0002469 {source="FMA"} ! esophagus mucosa

[Term]
id: UBERON:0001975
name: serosa of esophagus
namespace: uberon
def: "A serous membrane that is part of a esophagus [Automatically generated definition]." [OBOL:automatic]
synonym: "esophagus serosa" EXACT []
synonym: "esophagus serous membrane" EXACT [OBOL:automatic]
synonym: "gullet serosa" EXACT [OBOL:automatic]
synonym: "gullet serous membrane" EXACT [OBOL:automatic]
synonym: "oesophagus serosa" RELATED []
synonym: "oesophagus serous membrane" EXACT [OBOL:automatic]
synonym: "serosa of abdominal part of esophagus" EXACT []
synonym: "serosa of gullet" EXACT [OBOL:automatic]
synonym: "serosa of oesophagus" EXACT []
synonym: "serous coat of oesophagus" EXACT []
synonym: "serous membrane of esophagus" EXACT [OBOL:automatic]
synonym: "serous membrane of gullet" EXACT [OBOL:automatic]
synonym: "serous membrane of oesophagus" EXACT [OBOL:automatic]
synonym: "tunica serosa oesophageae" EXACT OMO:0003011 [FMA:63057, FMA:TA]
xref: EMAPA:35322
xref: FMA:63057
xref: MA:0001571
is_a: UBERON:0000042 ! serous membrane
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001096 ! wall of esophagus

[Term]
id: UBERON:0001976
name: epithelium of esophagus
namespace: uberon
def: "The epithelial layer that lines the luminal space of the esophagus." [ISBN:0-683-40008-8, MP:0000468]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "epithelial tissue of esophagus" EXACT [OBOL:automatic]
synonym: "epithelial tissue of gullet" EXACT [OBOL:automatic]
synonym: "epithelial tissue of oesophagus" EXACT [OBOL:automatic]
synonym: "epithelium of gullet" EXACT [OBOL:automatic]
synonym: "epithelium of oesophagus" EXACT [OBOL:automatic]
synonym: "esophageal epithelium" EXACT []
synonym: "esophagus epithelial tissue" EXACT [OBOL:automatic]
synonym: "esophagus epithelium" EXACT []
synonym: "gullet epithelial tissue" EXACT [OBOL:automatic]
synonym: "gullet epithelium" EXACT [OBOL:automatic]
synonym: "oesophagus epithelial tissue" EXACT [OBOL:automatic]
synonym: "oesophagus epithelium" RELATED []
xref: BTO:0001578
xref: CALOHA:TS-0698
xref: EFO:0003041
xref: EHDAA2:0001287
xref: EMAPA:16835
xref: FMA:63063
xref: MA:0001565
xref: NCIT:C49221
xref: TAO:0001499
xref: UMLS:C1179544 {source="ncithesaurus:Esophageal_Epithelium"}
xref: ZFA:0001499
is_a: UBERON:0003350 ! epithelium of mucosa
is_a: UBERON:0003929 ! digestive tract epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: contributes_to_morphology_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0002469 {source="FMA"} ! esophagus mucosa
property_value: editor_note "TODO check epithelium types: in FMA: Nonkeratinizing stratified squamous epithelium; mouse has basal and squamous subtypes; in ZFA it is columnar" xsd:string
property_value: UBPROP:0000001 "Simple columnar epithelium that lines the esophagus. Chen et al, 2007.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001499", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0001978
name: parenchyma of pancreas
namespace: uberon
subset: human_reference_atlas
synonym: "pancreas parenchyma" EXACT []
synonym: "pancreatic parenchyma" EXACT []
xref: EMAPA:32925
xref: FMA:63120
xref: MA:0000724
xref: SCTID:371401008
xref: VHOG:0001430
is_a: UBERON:0000353 ! parenchyma
intersection_of: UBERON:0000353 ! parenchyma
intersection_of: part_of UBERON:0001264 ! pancreas
relationship: part_of UBERON:0001264 ! pancreas
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001979
name: venule
namespace: uberon
def: "One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins." [MESH:A07.231.432.952, MP:0004125]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "venula" RELATED OMO:0003011 [Wikipedia:Venule]
xref: BTO:0002626
xref: EMAPA:35917
xref: FMA:63130
xref: MA:0000071
xref: MESH:D014699
xref: NCIT:C12818
xref: SCTID:341687009
xref: TAO:0005315
xref: UMLS:C0042520 {source="ncithesaurus:Venule"}
xref: VHOG:0001765
xref: Wikipedia:Venule
xref: ZFA:0005315
is_a: UBERON:0003920 ! venous blood vessel
is_a: UBERON:8410081 ! blood microvessel
relationship: connects UBERON:0001638 ! vein
relationship: connects UBERON:0001982 ! capillary
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/da/Illu_capillary.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Multi-tissue structure part of the blood vasculature formed by the anastomosis of capillaries. Venules carry blood toward the heart.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005315", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0001980
name: arteriole
namespace: uberon
def: "The smallest division of the artery located between the muscular arteries and the capillaries[GO]." [GO:0014830]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "arteriola" RELATED OMO:0003011 [Wikipedia:Arteriole]
xref: AAO:0010253
xref: BTO:0001997
xref: EMAPA:35146
xref: FMA:63182
xref: MA:0000063
xref: MESH:D001160
xref: NCIT:C12672
xref: SCTID:337724002
xref: TAO:0002138
xref: UMLS:C0003847 {source="ncithesaurus:Arteriole"}
xref: VHOG:0001763
xref: Wikipedia:Arteriole
xref: ZFA:0005255
is_a: UBERON:0003509 {source="MA"} ! arterial blood vessel
is_a: UBERON:8410081 ! blood microvessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: connects UBERON:0001637 ! artery
intersection_of: connects UBERON:0001982 ! capillary
relationship: connects UBERON:0001637 ! artery
relationship: connects UBERON:0001982 ! capillary
relationship: contributes_to_morphology_of UBERON:0001637 ! artery
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/da/Illu_capillary.jpg" xsd:anyURI
property_value: UBPROP:0000001 "Multi-tissue structure part of the blood vasculature, feeds into capillaries. Arterioles carry blood away from the heart.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002138", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Small, terminal branch of an artery which generally connects to capillaries.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010253", ontology="AAO", source="AAO:BJB"}

[Term]
id: UBERON:0001981
name: blood vessel
namespace: uberon
def: "A vessel through which blood circulates in the body." [BTO:0001102, Wikipedia:Blood_vessel]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "region of vascular tree organ" EXACT [FMA:50722]
synonym: "vas sanguineum" RELATED OMO:0003011 [Wikipedia:Blood_vessel]
synonym: "vascular element" BROAD [EMAPA:35993]
synonym: "vascular tree organ region" EXACT [FMA:50722]
xref: AAO:0011004
xref: AEO:0000207
xref: BTO:0001102
xref: CALOHA:TS-0080
xref: EFO:0000817
xref: EHDAA2:0003252
xref: EHDAA:240
xref: EMAPA:32743
xref: EMAPA:35993
xref: FMA:50722
xref: FMA:63183
xref: GAID:169
xref: MA:0000060
xref: MAT:0000393
xref: MESH:D001808
xref: NCIT:C12679
xref: NLXANAT:090901
xref: SCTID:361097006
xref: TAO:0002137
xref: UMLS:C0005847 {source="ncithesaurus:Blood_Vessel"}
xref: VHOG:0001250
xref: Wikipedia:Blood_vessel
xref: XAO:0001011
xref: ZFA:0005314
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000055 ! vessel
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: capable_of_part_of GO:0008015 ! blood circulation
relationship: channel_for UBERON:0000178 ! blood
relationship: develops_from UBERON:0004872 ! splanchnic layer of lateral plate mesoderm
relationship: develops_from UBERON:0006965 {source="GO:0072360"} ! vascular cord
relationship: has_part CL:0000071 {source="AEO"} ! blood vessel endothelial cell
relationship: has_part UBERON:0007500 {source="EHDAA2"} ! epithelial tube open at both ends
relationship: has_quality PATO:0002045 ! dendritic
relationship: part_of UBERON:0004537 ! blood vasculature
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI
property_value: editor_note "consider adopting the EMAPA superclass 'vascular element', which includes microvasculature (e.g. capillaries), vascular plexus" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Any of the vessels through which blood circulates in the body. [XAO:0001011_][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001250", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000001 "Any of the vessels through which blood circulates in the body.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011004", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001250", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "annelids have blood vessels, but this class is not applicable to annelids." xsd:string
property_value: UBPROP:0000012 "FMA:63183 Blood vessel is categorized as 'general anatomical term'. Suggestion to map to region of vascular tree from Terry H at JAX" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0001982
name: capillary
namespace: uberon
def: "Any of the smallest blood vessels connecting arterioles with venules." [https://github.com/obophenotype/uberon/issues/137, ISBN:0073040584, Wikipedia:Capillary]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "blood capillary" EXACT []
synonym: "capillary vessel" EXACT []
xref: AAO:0010252
xref: BTO:0002045
xref: CALOHA:TS-2006
xref: EFO:0001906
xref: EMAPA:35198
xref: EV:0100035
xref: FMA:63194
xref: MA:0000065
xref: MESH:D002196
xref: NCIT:C12685
xref: NLXANAT:090902
xref: TAO:0005250
xref: UMLS:C0935624 {source="ncithesaurus:Capillary"}
xref: VHOG:0001253
xref: Wikipedia:Capillary
xref: XAO:0000116
xref: ZFA:0005250
is_a: UBERON:8410081 ! blood microvessel
intersection_of: UBERON:8410081 ! blood microvessel
intersection_of: connects UBERON:0001979 ! venule
intersection_of: connects UBERON:0001980 ! arteriole
relationship: connects UBERON:0001979 ! venule
relationship: connects UBERON:0001980 ! arteriole
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/2f/A_red_blood_cell_in_a_capillary,_pancreatic_tissue_-_TEM.jpg" xsd:anyURI
property_value: editor_note "not all sources agree capillary is a blood vessel - consider adopting EMAPA superclass of vascular element" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/2186" xsd:string
property_value: UBPROP:0000001 "Any of the tiny blood vessels connecting the arterioles to the venules.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010252", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001253", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000010 "capillaries lack tunica media and tunica adventitia; only the endothelial wall of the tunica intima belongs" xsd:string

[Term]
id: UBERON:0001985
name: corneal endothelium
namespace: uberon
def: "A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]." [Wikipedia:Corneal_endothelium]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cornea endothelium" EXACT [OBOL:automatic]
synonym: "endothelium of cornea" EXACT [OBOL:automatic]
synonym: "epithelium posterius corneae" RELATED OMO:0003011 [Wikipedia:Corneal_endothelium]
xref: CALOHA:TS-0172
xref: EMAPA:35935
xref: FMA:63882
xref: GAID:891
xref: MA:0001242
xref: MESH:D004728
xref: NCIT:C12707
xref: SCTID:368827009
xref: TAO:0002186
xref: UMLS:C0014259 {source="ncithesaurus:Corneal_Endothelium"}
xref: Wikipedia:Corneal_endothelium
xref: ZFA:0001687
is_a: UBERON:0001986 ! endothelium
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0015808 ! eye epithelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0000964 ! cornea
relationship: adjacent_to UBERON:0001766 ! anterior chamber of eyeball
relationship: contributes_to_morphology_of UBERON:0000964 ! cornea
relationship: part_of UBERON:0000964 ! cornea
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0001986
name: endothelium
namespace: uberon
def: "A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA]." [FMA:63916, https://github.com/obophenotype/uberon/issues/225, MESH:A10.272.491]
comment: The term 'endothelium' has been either restricted to the continuous cell layer of the vertebrates, as we are assuming here, or applied to all the cells able to adhere to the luminal surface of the vascular basement membrane (Casley-Smith 1980)
subset: efo_slim
subset: human_reference_atlas
subset: uberon_slim
xref: BTO:0000393
xref: CALOHA:TS-0278
xref: EFO:0002548
xref: FMA:63916
xref: GAID:520
xref: galen:Endothelium
xref: MESH:D004727
xref: NCIT:C12481
xref: SCTID:27168002
xref: UMLS:C0014257 {source="ncithesaurus:Endothelium"}
is_a: UBERON:0000487 {source="FMA-text-def", source="https://github.com/obophenotype/uberon/issues/225"} ! simple squamous epithelium
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: composed_primarily_of CL:0000115 ! endothelial cell
relationship: composed_primarily_of CL:0000115 ! endothelial cell
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000007 "endothelial" xsd:string

[Term]
id: UBERON:0001987
name: placenta
namespace: uberon
def: "Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell." [http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm, Wikipedia:Placenta]
comment: Marsupials possess only a rudimentary yolk-type placenta, with reduced nutrient and oxygen exchanging capabilities.
subset: efo_slim
subset: human_reference_atlas
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "allantoic placenta" EXACT [ISBN:0073040584]
synonym: "eutherian placenta" EXACT []
xref: BTO:0001078
xref: CALOHA:TS-0799
xref: EFO:0001407
xref: EMAPA:35689
xref: EV:0100119
xref: FMA:63934
xref: GAID:379
xref: MA:0000386
xref: MAT:0000279
xref: MESH:D010920
xref: MIAA:0000279
xref: NCIT:C13272
xref: SCTID:181455002
xref: UMLS:C0032043 {source="ncithesaurus:Placenta"}
xref: VHOG:0001266
xref: Wikipedia:Placenta
is_a: UBERON:0000062 ! organ
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
relationship: develops_from UBERON:0000995 {source="ISBN:0073040584"} ! uterus
relationship: develops_from UBERON:0003124 {source="Wikipedia"} ! chorion membrane
relationship: develops_from UBERON:0004340 {source="ISBN:0073040584"} ! allantois
relationship: only_in_taxon NCBITaxon:32525 {source="https://github.com/obophenotype/uberon/issues/1376"} ! Theria <mammals>
relationship: part_of UBERON:0000474 ! female reproductive system
relationship: part_of UBERON:0016887 ! entire extraembryonic component
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/66/Placenta.jpg" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f1/Placenta.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "Phylogenetic analyses of the concatenated data set using maximum parsimony, maximum likelihood and distance based (neighbour joining) methods all converged on a nearly identical, well supported topology defining four principal eutherian lineages. The results affirm monophyly of traditional placental orders (except Artiodactyla and Insectivora), and also support some previously proposed, as well as new, superordinal clades.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001266", ontology="VHOG", source="DOI:10.1038/35054550 Murphy WJ, Eizirik E, Johnson WE, Zhang YP, Ryder OA, O'Brien SJ, Molecular phylogenetics and the origins of placental mammals. Nature (2001)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "placental" xsd:string
property_value: UBPROP:0000008 "Eutherians: In eutherians, the chorioallantoic membrane of the fetus establishes intimate contact with the adjacent vascular wall of the mother's uterus to produce the placenta, a composite structure formed in part from tissues of the fetus and in part from tissues of the mother [ISBN:0073040584 (Vertebrates, Kardong)]. TODO - is taxon restriction too strict, even if we restrict def to allantoic placenta? - WP says: also found in some snakes and lizards with varying levels of development up to mammalian levels. Pough et al. 1992. Herpetology: Third Edition. Pearson Prentice Hall:Pearson Education, Inc., 2002. // See also: DOI:10.1002/jmor.11011" xsd:string

[Term]
id: UBERON:0001988
name: feces
namespace: uberon
def: "Portion of semisolid bodily waste discharged through the anus[MW,modified]." [http://www.merriam-webster.com/dictionary/feces, Wikipedia:Feces]
subset: pheno_slim
subset: uberon_slim
synonym: "cow dung" NARROW [Wikipedia:Cow_dung]
synonym: "cow pat" NARROW [Wikipedia:Cow_dung]
synonym: "droppings" RELATED []
synonym: "dung" NARROW []
synonym: "excrement" RELATED [BTO:0000440]
synonym: "excreta" BROAD []
synonym: "faeces" EXACT []
synonym: "fecal material" EXACT []
synonym: "fecal matter" EXACT []
synonym: "fewmet" NARROW [Wikipedia:Fewmet]
synonym: "frass" NARROW [Wikipedia:Frass]
synonym: "guano" NARROW [Wikipedia:Guano]
synonym: "ordure" RELATED []
synonym: "piece of shit" EXACT [PMID:23285307]
synonym: "portion of dung" NARROW []
synonym: "portion of excrement" EXACT []
synonym: "portion of faeces" EXACT []
synonym: "portion of fecal material" EXACT []
synonym: "portion of fecal matter" EXACT []
synonym: "portion of feces" EXACT []
synonym: "portion of guano" NARROW []
synonym: "portion of scat" NARROW []
synonym: "portionem cacas" EXACT OMO:0003011 []
synonym: "scat" NARROW []
synonym: "spoor" RELATED []
synonym: "spraint" NARROW [Wikipedia:Spraint]
synonym: "stool" EXACT []
xref: BTO:0000440
xref: CALOHA:TS-2345
xref: ENVO:00002003
xref: FMA:64183
xref: GAID:1199
xref: galen:Feces
xref: MA:0002509
xref: MAT:0000053
xref: MESH:D005243
xref: MIAA:0000053
xref: NCIT:C13234
xref: UMLS:C0015733 {source="ncithesaurus:Feces"}
xref: Wikipedia:Feces
is_a: UBERON:0000174 ! excreta
intersection_of: UBERON:0000174 ! excreta
intersection_of: output_of GO:0030421 ! defecation
relationship: output_of GO:0030421 ! defecation
property_value: UBPROP:0000001 "Excretion in semisolid state processed by the intestine.[FMA]" xsd:string {source="FMA:64183"}
property_value: UBPROP:0000007 "fecal" xsd:string

[Term]
id: UBERON:0002012
name: pulmonary artery
namespace: uberon
def: "An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Pulmonary_artery]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "arteria pulmonalis" RELATED OMO:0003011 [Wikipedia:Pulmonary_artery]
synonym: "pulmonary arterial subtree" RELATED [FMA:66326]
synonym: "pulmonary arterial tree" EXACT [FMA:66326]
synonym: "pulmonary arterial tree organ part" EXACT [FMA:66326]
synonym: "truncus pulmonalis" RELATED OMO:0003011 [Wikipedia:Pulmonary_artery]
xref: AAO:0010221
xref: BTO:0000778
xref: CALOHA:TS-0839
xref: EFO:0001399
xref: EHDAA2:0001575
xref: EHDAA:4351
xref: EMAPA:17008
xref: FMA:66326
xref: GAID:505
xref: galen:PulmonaryArtery
xref: MA:0002031
xref: MESH:D011651
xref: NCIT:C12774
xref: SCTID:181380003
xref: UMLS:C0034052 {source="ncithesaurus:Pulmonary_Artery"}
xref: VHOG:0000982
xref: Wikipedia:Pulmonary_artery
xref: XAO:0004162
is_a: UBERON:0001637 ! artery
is_a: UBERON:0013768 ! great vessel of heart
intersection_of: UBERON:0001637 ! artery
intersection_of: part_of UBERON:0008886 ! pulmonary vascular system
intersection_of: supplies UBERON:0002048 ! lung
disjoint_from: UBERON:0004573 ! systemic artery
relationship: continuous_with UBERON:0002333 ! pulmonary trunk
relationship: develops_from UBERON:0002061 {source="Wikipedia"} ! truncus arteriosus
relationship: develops_from UBERON:0003123 {source="EHDAA2", source="XAO"} ! pharyngeal arch artery 6
relationship: develops_from UBERON:0005339 {source="EHDAA2"} ! outflow tract pulmonary component
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0008886 ! pulmonary vascular system
relationship: supplies UBERON:0002048 ! lung
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Major artery which supplies blood to the lungs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010221", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "One of two arteries, leaving from the heart, the left one supplying the left lung and the right one supplying the right lung. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000982", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/pulmonary+artery"}
property_value: UBPROP:0000003 "On the other hand, in the sister clade of the actinopterygians, the sarcopterygians, the gill circulation is supplemented with lung ventilation. As a result, the pulmonary artery and vein and a functional ductus arteriosus arose as a major evolutionary innovation from the sixth arch, giving the organism a flexible shunt to balance blood supply to and from gills and lungs according to environmental conditions.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000982", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "In the human heart, the pulmonary trunk (pulmonary artery or main pulmonary artery) begins at the base of the right ventricle. It is short and wide - approximately 5 cm (2 inches) in length and 3 cm (1.2 inches) in diameter. It then branches into two pulmonary arteries (left and right), which deliver deoxygenated blood to the corresponding lung[WP]" xsd:string

[Term]
id: UBERON:0002015
name: kidney capsule
namespace: uberon
def: "The tough fibrous layer surrounding the kidney which is covered in a thick layer of perirenal adipose tissue that functions to provide some protection from trauma and damage." [MGI:anna, MP:0011383]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "capsula fibrosa renis" EXACT OMO:0003011 [FMA:66610, FMA:TA]
synonym: "capsule of kidney" EXACT []
synonym: "fibrous capsule of kidney" EXACT [FMA:66610]
synonym: "renal capsule" EXACT [GO:0072127]
xref: EMAPA:18679
xref: FMA:66610
xref: galen:CapsuleOfKidney
xref: MA:0000370
xref: NCIT:C12885
xref: SCTID:243657006
xref: UMLS:C0227637 {source="ncithesaurus:Renal_Capsule"}
xref: Wikipedia:Kidney_capsule
is_a: UBERON:0003567 ! abdomen connective tissue
is_a: UBERON:0011824 ! fibrous connective tissue
intersection_of: UBERON:0011824 ! fibrous connective tissue
intersection_of: bounding_layer_of UBERON:0002113 ! kidney
relationship: bounding_layer_of UBERON:0002113 ! kidney
relationship: contributes_to_morphology_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0002113 ! kidney
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Kidney_L.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Kidney_R.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_L.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_R.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000009 "provides some protection from trauma and damage." xsd:string
property_value: UBPROP:0000010 "The renal capsule relates to the other layers in the following order (moving from innermost to outermost): renal medulla renal cortex renal capsule perinephric fat (or 'perirenal fat') renal fascia paranephric fat (or 'pararenal fat') peritoneum (anteriorly), and transversalis fascia (posteriorly).[Wikipedia:Kidney_capsule]" xsd:string

[Term]
id: UBERON:0002016
name: pulmonary vein
namespace: uberon
def: "Pulmonary veins are blood vessels that transport blood from the lungs to the heart[GO]." [GO:0060577]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "pulmonary venous tree organ part" EXACT []
synonym: "venae pulmonales" RELATED OMO:0003011 [Wikipedia:Pulmonary_vein]
xref: AAO:0010521
xref: BTO:0001799
xref: CALOHA:TS-0840
xref: EHDAA2:0001579
xref: EHDAA:2629
xref: EMAPA:18645
xref: FMA:66643
xref: GAID:543
xref: galen:PulmonaryVein
xref: MA:0002206
xref: MESH:D011667
xref: NCIT:C12776
xref: SCTID:430160002
xref: UMLS:C0034090 {source="ncithesaurus:Pulmonary_Vein"}
xref: VHOG:0001133
xref: Wikipedia:Pulmonary_vein
xref: XAO:0000394
is_a: UBERON:0001638 ! vein
is_a: UBERON:0013768 ! great vessel of heart
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0002048 ! lung
relationship: connected_to UBERON:0002079 ! left cardiac atrium
relationship: develops_from UBERON:0002061 ! truncus arteriosus
relationship: drains UBERON:0002048 ! lung
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0008886 ! pulmonary vascular system
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Any of the veins which collect blood from the lungs and some small vesicles received from the esophagus.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010521", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "One of two pairs of large vessels that return oxygenated blood from each lung to the left atrium of the heart. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001133", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/pulmonary+vein"}
property_value: UBPROP:0000001 "the veins that return oxygenated blood from the lungs to the left atrium of the heart" xsd:string {source="MP:0002726,MGI:cwg"}
property_value: UBPROP:0000003 "On the other hand, in the sister clade of the actinopterygians, the sarcopterygians, the gill circulation is supplemented with lung ventilation. As a result, the pulmonary artery and vein and a functional ductus arteriosus arose as a major evolutionary innovation from the sixth arch, giving the organism a flexible shunt to balance blood supply to and from gills and lungs according to environmental conditions.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001133", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000202 FMA:70827

[Term]
id: UBERON:0002017
name: portal vein
namespace: uberon
def: "A vein that conducts blood from the digestive organs, spleen, pancreas, and gallbladder to the liver[BTO]." [BTO:0001792]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "portal venous tree organ part" EXACT [FMA:66645]
xref: BTO:0001792
xref: CALOHA:TS-0814
xref: EHDAA2:0001485
xref: EHDAA:6510
xref: EMAPA:17349
xref: FMA:66645
xref: GAID:540
xref: galen:PortalVein
xref: MA:0002198
xref: MESH:D011169
xref: NCIT:C33343
xref: SCTID:362064007
xref: UMLS:C0032718 {source="ncithesaurus:Portal_Vein"}
xref: VHOG:0000656
xref: XAO:0000392
is_a: UBERON:0001638 {source="FMA"} ! vein
relationship: part_of UBERON:0005806 ! portal system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002020
name: gray matter
namespace: uberon
def: "A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Gray_matter]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "gray mater" RELATED [ZFA:0001681]
synonym: "gray matter" EXACT []
synonym: "gray matter of neuraxis" EXACT [FMA:67242]
synonym: "grey matter" EXACT []
synonym: "grey matter of neuraxis" EXACT []
synonym: "grey substance" EXACT []
synonym: "grisea" RELATED OMO:0003011 []
synonym: "neuronal grey matter" EXACT [AEO:0001012]
synonym: "substantia grisea" EXACT OMO:0003011 [FMA:67242, FMA:TA]
xref: AEO:0001012
xref: EHDAA2:0003136
xref: EHDAA2_RETIRED:0004658
xref: EMAPA:37596 {source="MA:th"}
xref: FMA:67242
xref: HBA:4006
xref: MA:0001112
xref: MESH:D066128 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C32695
xref: neuronames:2869
xref: TAO:0002197
xref: UMLS:C0018220 {source="ncithesaurus:Gray_Matter"}
xref: VHOG:0001768
xref: Wikipedia:Gray_matter
xref: ZFA:0001681
is_a: UBERON:0011215 ! central nervous system cell part cluster
relationship: composed_primarily_of GO:0043025 ! neuronal cell body
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg" xsd:anyURI
property_value: UBPROP:0000001 "Multi-tissue comprised of neurons, dendrites, axon terminals, glial cells, and capillaries.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002197", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0002028
name: hindbrain
namespace: uberon
def: "The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]." [Wikipedia:Rhombencephalon, ZFA:0000029, ZFIN:curator]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "rhombencephalon" RELATED []
xref: AAO:0010150
xref: BAMS:HB
xref: BIRNLEX:942
xref: BTO:0000672
xref: CALOHA:TS-0457
xref: DHBA:10653
xref: DMBA:16808
xref: EFO:0000923
xref: EHDAA2:0000746
xref: EHDAA:3514
xref: EHDAA:6487
xref: EMAPA:16916
xref: FMA:67687
xref: MA:0000195
xref: MAT:0000107
xref: MBA:1065
xref: MESH:D012249
xref: MIAA:0000107
xref: NCIT:C40336
xref: neuronames:540 {source="BIRNLEX:942"}
xref: SCTID:303456008
xref: TAO:0000029
xref: UMLS:C0035507 {source="ncithesaurus:Hind-Brain", source="BIRNLEX:942"}
xref: UMLS:C1522180 {source="BIRNLEX:942"}
xref: VHOG:0000070
xref: Wikipedia:Rhombencephalon
xref: XAO:0000015
xref: ZFA:0000029
is_a: UBERON:0002616 ! regional part of brain
relationship: contributes_to_morphology_of UBERON:0000955 ! brain
relationship: develops_from UBERON:0007277 ! presumptive hindbrain
relationship: immediate_transformation_of UBERON:0007277 {source="Bgee:AN"} ! presumptive hindbrain
relationship: only_in_taxon NCBITaxon:89593 ! Craniata <chordates>
relationship: overlaps UBERON:0002298 {notes="modified-source-relation", source="ABA"} ! brainstem
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg" xsd:anyURI
property_value: RO:0002171 UBERON:0001891 {exceptions="ZFA", source="ABA", source="https://github.com/obophenotype/uberon/issues/378", status="pending"}
property_value: RO:0002171 UBERON:0001894 {source="ABA"}
property_value: RO:0002175 NCBITaxon:7762 {source="PMID:8932866"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Posterior part of the brain consisting of the cerebellum and medulla oblongata.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010150", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The most posterior of the three principal regions of the brain, forming the rhombencephalon and all or most of the metencephalon. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000029", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000002 "relationship loss: develops_from hindbrain neural tube (TAO:0007043)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000029", ontology="TAO"}
property_value: UBPROP:0000003 "Fine structural, computerized three-dimensional (3D) mapping of cell connectivity in the amphioxus nervous system and comparative molecular genetic studies of amphioxus and tunicates have provided recent insights into the phylogenetic origin of the vertebrate nervous system. The results suggest that several of the genetic mechanisms for establishing and patterning the vertebrate nervous system already operated in the ancestral chordate and that the nerve cord of the proximate invertebrate ancestor of the vertebrates included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000070", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "rhombencephalic" xsd:string
property_value: UBPROP:0000012 "in MA, brainstem and hindbrain and part-of siblings under brain, consistent with FMA and NIF. See also notes for cerebellum. We weaken the relation in ABA to overlaps" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0002029
name: epithelium of gall bladder
namespace: uberon
def: "The simple columnar epithelial lining of the gall bladder." [MP:0009492]
subset: pheno_slim
synonym: "biliary epithelium" RELATED []
synonym: "epithelial tissue of gall bladder" EXACT [OBOL:automatic]
synonym: "epithelial tissue of gallbladder" EXACT [OBOL:automatic]
synonym: "epithelium of gallbladder" EXACT [OBOL:automatic]
synonym: "gall bladder epithelial tissue" EXACT [OBOL:automatic]
synonym: "gall bladder epithelium" EXACT []
synonym: "gallbladder epithelial tissue" EXACT [OBOL:automatic]
synonym: "gallbladder epithelium" EXACT [OBOL:automatic]
xref: BTO:0001449
xref: CALOHA:TS-1304
xref: EMAPA:35370
xref: FMA:67711
xref: MA:0001632
xref: NCIT:C49227
xref: UMLS:C1180206 {source="ncithesaurus:Gallbladder_Epithelium"}
is_a: UBERON:0000485 ! simple columnar epithelium
is_a: UBERON:0005911 ! endo-epithelium
is_a: UBERON:0034932 ! epithelium of biliary system
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0002110 ! gallbladder
relationship: contributes_to_morphology_of UBERON:0002110 ! gallbladder
relationship: part_of UBERON:0002110 ! gallbladder

[Term]
id: UBERON:0002036
name: striated muscle tissue
namespace: uberon
def: "Muscle tissue that contains fibers that are divided by transverse bands into striations." [CL:0000737, GOC:dph, GOC:mtg_muscle]
subset: pheno_slim
subset: uberon_slim
synonym: "striated muscle" EXACT []
xref: AAO:0010762
xref: AEO:0000140
xref: CALOHA:TS-2047
xref: EHDAA2:0003140
xref: EMAPA:36390
xref: FMA:67905
xref: galen:StriatedMuscle
xref: MA:0002438
xref: NCIT:C12436
xref: UMLS:C1331262 {source="ncithesaurus:Striated_Muscle_Tissue"}
xref: WBbt:0005779
xref: Wikipedia:Striated_muscle
is_a: UBERON:0002385 ! muscle tissue
intersection_of: UBERON:0002385 ! muscle tissue
intersection_of: composed_primarily_of CL:0000737 ! striated muscle cell
relationship: composed_primarily_of CL:0000737 ! striated muscle cell
property_value: UBPROP:0000001 "Voluntary muscle tissue arranged in bundles of fibers.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010762", ontology="AAO", source="AAO:CAM"}

[Term]
id: UBERON:0002040
name: bronchial artery
namespace: uberon
def: "A systemic artery that supplies the lung with with oxygenated blood." [UBERON:cjm, Wikipedia:Bronchial_artery]
comment: Although there is much variation, there are usually two bronchial arteries that run to the left lung, and one to the right lung.
subset: human_reference_atlas
subset: uberon_slim
synonym: "arteriae bronchiales" RELATED OMO:0003011 [Wikipedia:Bronchial_artery]
synonym: "bronchial arterial tree" EXACT []
synonym: "rami bronchiales partis thoracicae aortae" RELATED OMO:0003011 [Wikipedia:Bronchial_artery]
xref: EMAPA:18608
xref: FMA:68109
xref: GAID:477
xref: MA:0001923
xref: MESH:D001981
xref: NCIT:C32230
xref: SCTID:244247009
xref: UMLS:C0006257 {source="ncithesaurus:Bronchial_Artery"}
xref: Wikipedia:Bronchial_artery
is_a: UBERON:0004573 ! systemic artery
intersection_of: UBERON:0004573 ! systemic artery
intersection_of: part_of UBERON:0004571 ! systemic arterial system
intersection_of: supplies UBERON:0002048 ! lung
relationship: has_part UBERON:0004848 ! respiratory system arterial endothelium
relationship: has_part UBERON:0012416 ! respiratory system arterial smooth muscle
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0002048 ! lung
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/a7/Gray1032.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002047
name: pontine raphe nucleus
namespace: uberon
def: "The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]." [Wikipedia:Pontine_raphe_nucleus]
subset: pheno_slim
subset: uberon_slim
synonym: "nucleus raphe pontis" RELATED OMO:0003011 [NeuroNames:589]
synonym: "nucleus raphes pontis" RELATED OMO:0003011 [Wikipedia:Pontine_raphe_nucleus]
synonym: "raphe (mediana pontina)" RELATED OMO:0003011 [NeuroNames:589]
synonym: "raphe of pons" EXACT []
synonym: "raphe pontis" EXACT OMO:0003011 [FMA:68875, FMA:TA]
synonym: "raphe pontis nucleus" RELATED []
xref: BAMS:PnR
xref: BAMS:RA-PONS
xref: BAMS:RPn
xref: BIRNLEX:1110
xref: DHBA:12471
xref: DHBA:12475
xref: FMA:68875
xref: HBA:9159
xref: MA:0001022
xref: MBA:238
xref: neuronames:589 {source="BIRNLEX:1110"}
xref: UMLS:C0175423 {source="BIRNLEX:1110"}
xref: Wikipedia:Pontine_raphe_nucleus
is_a: UBERON:0006331 ! brainstem nucleus
is_a: UBERON:0009662 ! hindbrain nucleus
relationship: part_of UBERON:0003023 ! pontine tegmentum
relationship: part_of UBERON:0004684 {source="Wikipedia"} ! raphe nuclei
property_value: RO:0002171 UBERON:0002148 {source="ABA"}
property_value: RO:0002171 UBERON:0002267 {source="ABA"}
property_value: RO:0002171 UBERON:0002587 {source="ABA"}
property_value: RO:0002171 UBERON:0003004 {source="ABA"}

[Term]
id: UBERON:0002048
name: lung
namespace: uberon
def: "Respiration organ that develops as an outpocketing of the esophagus." [http://orcid.org/0000-0002-6601-2165]
comment: Snakes and limbless lizards typically possess only the right lung as a major respiratory organ; the left lung is greatly reduced, or even absent. Amphisbaenians, however, have the opposite arrangement, with a major left lung, and a reduced or absent right lung [WP]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "pulmo" EXACT OMO:0003011 []
xref: AAO:0000275
xref: AAO:0010567
xref: BTO:0000763
xref: CALOHA:TS-0568
xref: EFO:0000934
xref: EHDAA2:0001042
xref: EHDAA:1554
xref: EHDAA:2205
xref: EMAPA:16728
xref: EV:0100042
xref: FMA:7195
xref: GAID:345
xref: galen:Lung
xref: MA:0000415
xref: MAT:0000135
xref: MESH:D008168
xref: MIAA:0000135
xref: NCIT:C12468
xref: SCTID:181216001
xref: UMLS:C0024109 {source="ncithesaurus:Lung"}
xref: VHOG:0000310
xref: Wikipedia:Lung
xref: XAO:0000119
is_a: UBERON:0000171 ! respiration organ
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0005178 ! thoracic cavity element
is_a: UBERON:0015212 ! lateral structure
relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system
relationship: develops_from UBERON:0000118 ! lung bud
relationship: in_lateral_side_of UBERON:0000170 ! pair of lungs
relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata <vertebrates>
relationship: part_of UBERON:0000170 {note="some species only have a single lung"} ! pair of lungs
relationship: surrounded_by UBERON:0009778 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! pleural sac
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb" xsd:anyURI
property_value: RO:0002161 NCBITaxon:32443 {editor="https://orcid.org/0000-0002-9415-5104", source="https://github.com/obophenotype/uberon/issues/701"}
property_value: RO:0002161 NCBITaxon:7777 {editor="https://orcid.org/0000-0002-9415-5104", source="https://github.com/obophenotype/uberon/issues/701"}
property_value: RO:0002175 NCBITaxon:9606
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/701" xsd:anyURI
property_value: UBPROP:0000001 "Either of two organs which allow gas exchange absorbing oxygen from inhaled air and releasing carbon dioxide with exhaled air.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010567", ontology="AAO", source="AAO:SBH"}
property_value: UBPROP:0000003 "Lungs had already developed as paired ventral pockets from the intestine in the ancestor of Osteognathostomata. (...) In actinopterygian fishes, apart from Cladistia, the ventral intestinal pocket migrates dorsally and becomes the swim-bladder, a mainly hydrostatical organ (reference 1); Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and Mammalian lung (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000310", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.210, DOI:10.1371/journal.pone.0024019 Zheng W, Wang Z, Collins JE, Andrews RM, Stemple D, Gong Z, Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and Mammalian lung. PLoS One (2011)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "pulmonary" xsd:string
property_value: UBPROP:0000008 "respiration organ in all air-breathing animals, including most tetrapods, a few fish and a few snails. In mammals and the more complex life forms, the two lungs are located in the chest on either side of the heart. Their principal function is to transport oxygen from the atmosphere into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere. This exchange of gases is accomplished in the mosaic of specialized cells that form millions of tiny, exceptionally thin-walled air sacs called alveoli. // Avian lungs do not have alveoli as mammalian lungs do, they have Faveolar lungs. They contain millions of tiny passages known as para-bronchi, connected at both ends by the dorsobronchi" xsd:string

[Term]
id: UBERON:0002049
name: vasculature
namespace: uberon
def: "An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face." [ZFA:0005249]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "vascular network" EXACT [FMA:69050]
xref: BTO:0003718
xref: FMA:69050
xref: TAO:0005249
xref: ZFA:0005249
is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster
relationship: composed_primarily_of UBERON:0000055 ! vessel
relationship: has_part UBERON:0000179 ! haemolymphatic fluid
relationship: part_of UBERON:0007798 ! vascular system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI
property_value: editor_note "see also: vascular system. Consider merging?" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000007 "vascular" xsd:string

[Term]
id: UBERON:0002050
name: embryonic structure
namespace: uberon
def: "Anatomical structure that is part of an embryo." [BTO:0000174, ZFIN:curator]
subset: efo_slim
subset: inconsistent_with_fma
subset: vertebrate_core
synonym: "developing embryonic structure" EXACT [FBbt:00004208]
synonym: "developing structure" RELATED []
synonym: "embryonale Struktur" RELATED [BTO:0000174]
synonym: "embryonic anatomical structure" EXACT [RETIRED_EHDAA2:0003169]
synonym: "embryonic structures" RELATED OMO:0003004 [ZFA:0001105]
xref: AAO:0000138
xref: BILA:0000034
xref: BTO:0000174
xref: CALOHA:TS-2110
xref: EFO:0000461
xref: FBbt:00004208 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:69067
xref: GAID:407
xref: MESH:D004628
xref: NCIT:C13229
xref: RETIRED_EHDAA2:0003169
xref: SCTID:667009
xref: TAO:0001105
xref: UMLS:C0013948 {source="ncithesaurus:Embryonic_Structure"}
xref: VSAO:0000178
xref: XAO:0003042
xref: ZFA:0001105
is_a: UBERON:0005423 ! developing anatomical structure
intersection_of: UBERON:0005423 ! developing anatomical structure
intersection_of: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0000922 ! embryo
property_value: UBPROP:0000001 "Anatomical structure that is part of the embryo and is comprised of portions of tissue or cells.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000138", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "Anatomical structure that is part of the embryo and is comprised of portions of tissue or cells.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001105", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Anatomical structure that is part of the embryo and is comprised of portions of tissue or cells.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000178", ontology="VSAO", source="ZFIN:curator"}
property_value: UBPROP:0000012 "in FMA embryo is_a embryonic structure" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0002057
name: phrenic artery
namespace: uberon
def: "An artery that supplies the diaphragm." [https://orcid.org/0000-0002-6601-2165]
subset: uberon_slim
xref: EMAPA:37108 {source="MA:th"}
xref: FMA:69330
xref: MA:0002019
xref: NCIT:C33320
xref: UMLS:C1181536 {source="ncithesaurus:Phrenic_Artery"}
is_a: UBERON:0004573 ! systemic artery
intersection_of: UBERON:0004573 ! systemic artery
intersection_of: supplies UBERON:0001103 ! diaphragm
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0001103 ! diaphragm
property_value: UBPROP:0000008 "In humans this includes the superior and inferior phrenic arteries" xsd:string

[Term]
id: UBERON:0002061
name: truncus arteriosus
namespace: uberon
def: "The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles." [Wikipedia:Truncus_arteriosus_(embryology)]
subset: uberon_slim
xref: EHDAA2:0004143
xref: EMAPA:35887
xref: FMA:70301
xref: GAID:554
xref: MA:0000103
xref: MESH:D014338
xref: NCIT:C34317
xref: SCTID:308828009
xref: UMLS:C1519589 {source="ncithesaurus:Trancus_Arteriosus"}
xref: Wikipedia:Truncus_arteriosus_(embryology)
is_a: UBERON:0001637 {source="EHDAA2"} ! artery
is_a: UBERON:0002050 {source="FMA"} ! embryonic structure
is_a: UBERON:0003498 ! heart blood vessel
relationship: develops_from UBERON:0005432 {source="EHDAA2"} ! aortic sac
relationship: part_of UBERON:0004145 {source="MA"} ! outflow tract
relationship: part_of UBERON:0005498 {source="EHDAA2"} ! primitive heart tube
property_value: UBPROP:0000012 "assume spelling error for ncit" xsd:string {external_ontology="ncit"}

[Term]
id: UBERON:0002062
name: endocardial cushion
namespace: uberon
def: "The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]." [GO:0003197, Wikipedia:Atrioventricular_cushions, ZFIN:curator]
comment: GO graph seems to suggest this is an endothelium. WP: The endocardial cushions are thought to arise from a subset of endothelial cells that undergo epithelial to mesenchymal transformation, a process whereby these cells break cell-to-cell contacts and migrate into the cardiac jelly (towards to interior of the heart tube). Latest (2010-06-01) new def suggested for GO, added above. Note that EHDAA2 has a more detailed model which we may later adopt. JB: Patterning makes the cushions lay down connective tissue in three domains that force out the local endothelial lining and so the leaflets form
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "atrioventricular canal cushion" RELATED [FMA:70302]
synonym: "atrioventricular cushion" EXACT [Wikipedia:Endocardial_cushion]
synonym: "AV cushion" EXACT []
synonym: "cardiac cushion" EXACT [PMID:15797462]
synonym: "endocardial cushion tissue" EXACT [EHDAA2:0000434]
synonym: "endocardial cushions" RELATED OMO:0003004 []
xref: EHDAA2:0000434
xref: EHDAA2:0004028
xref: EHDAA:2586
xref: EMAPA:16696
xref: FMA:70302
xref: MA:0000078
xref: MESH:D054089 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: TAO:0001317
xref: VHOG:0000932
xref: Wikipedia:Atrioventricular_cushions
xref: XAO:0004189
xref: ZFA:0001317
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0005256 ! trunk mesenchyme
is_a: UBERON:0009751 ! cardiac mesenchyme
is_a: UBERON:0014387 ! mesenchyme derived from neural crest
relationship: part_of UBERON:0002165 {source="ZFA"} ! endocardium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png" xsd:anyURI
property_value: UBPROP:0000001 "Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001317", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000002 "relationship loss: develops_from endocardial ring (TAO:0005072)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001317", ontology="TAO"}
property_value: UBPROP:0000003 "(Cardiac valve formation in vertebrates) In response to a myocardial signal, endocardial cells at chamber boundaries take on a mesenchymal character, delaminate and migrate into the cardiac jelly. There, they form an endocardial cushion that is later remodelled into a valve.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000932", ontology="VHOG", source="DOI:10.1038/35047564 Stainier DYR, Zebrafish genetics and vertebrate heart formation. Nature Reviews Genetics (2001) Figure 3", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002063
name: sinus venosus
namespace: uberon
def: "The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart." [PMID:20735616, Wikipedia:Sinus_venosus]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "inflow tract" BROAD [ZFA:0000154]
synonym: "sinus venarum" RELATED [Wikipedia:Sinus_venosus]
synonym: "sinus venosus cordis" RELATED OMO:0003011 [Wikipedia:Sinus_venosus]
synonym: "venarum" RELATED [Wikipedia:Sinus_venosus]
synonym: "venarum sinus" RELATED [Wikipedia:Sinus_venosus]
synonym: "venosus" RELATED [Wikipedia:Sinus_venosus]
xref: AAO:0010505
xref: EHDAA2:0001839
xref: EHDAA:480
xref: EMAPA:16237
xref: FMA:70303
xref: NCIT:C34299
xref: NCIT:C34300
xref: TAO:0000154
xref: UMLS:C0225857 {source="ncithesaurus:Sinus_Venarum"}
xref: UMLS:C0231084 {source="ncithesaurus:Sinus_Venosus"}
xref: VHOG:0000177
xref: Wikipedia:Sinus_venosus
xref: ZFA:0000154
is_a: UBERON:0004151 ! cardiac chamber
relationship: develops_from UBERON:0007278 ! presumptive sinus venosus
relationship: immediate_transformation_of UBERON:0007278 {source="Bgee:AN"} ! presumptive sinus venosus
relationship: part_of UBERON:0002350 {source="VHOG"} ! conducting system of heart
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png" xsd:anyURI
property_value: UBPROP:0000001 "Heart region collecting blood from the paired common cardinal veins and delivering to the atrium. One of four components of the heart. The sinus venosus also acts as a pacemaker and is the first to contract. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000154", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Part of the circulatory system which receives blood from the systemic veins and contracts to pump the blood into the atrium of the heart.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010505", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "In the primitive vertebrate heart the four chambers are: 1. Sinus venosus (...) 2. Atrium (...) 3. Ventricle (...) 4. Conus arteriosus (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000177", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970) p.428", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "In fish, receives venous blood from the systemic circulation through paired hepatic veins, anterior jugular veins and Cuvierian ducts[PMID:20735616]" xsd:string
property_value: UBPROP:0000008 "In humans, it exists distinctly only in the embryonic heart, where it is found between the two venae cavae. In the adult, it is incorporated into the wall of the right atrium to form a smooth part called the sinus venarum, also known as the venarum sinus, which is separated from the rest of the atrium by a ridge of fibres called the crista terminalis. The sinus venosus also forms the SA node and the coronary sinus. In the embryo, the thin walls of the sinus venosus are connected below with the right ventricle, and medially with the left atrium, but are free in the rest of their extent. It receives blood from the vitelline vein, umbilical vein and common cardinal vein. It originally starts as a paired structure but shifts towards associating only with the right atrium as the embryonic heart develops. The left portion shrinks in size and eventually forms the coronary sinus and oblique vein of the left atrium, whereas the right part becomes incorporated into the right atrium to form the sinus venarmu" xsd:string
property_value: UBPROP:0000008 "In zebrafish, the sinus venosus also acts as a pacemaker and is the first to contract" xsd:string {source="ZFA:0000154"}

[Term]
id: UBERON:0002067
name: dermis
namespace: uberon
def: "The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]." [Wikipedia:Dermis, ZFIN:curator]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "corium" RELATED OMO:0003011 [BTO:0000294, Wikipedia:Dermis]
synonym: "cutis" RELATED [BTO:0000294]
synonym: "vertebrate dermis" EXACT []
xref: AAO:0000128
xref: BTO:0000294
xref: CALOHA:TS-2076
xref: EFO:0000953
xref: EMAPA:17527
xref: EV:0100154
xref: FMA:70323
xref: GAID:1321
xref: MA:0000152
xref: MAT:0000153
xref: MESH:D020405
xref: MIAA:0000153
xref: NCIT:C12701
xref: SCTID:361696001
xref: TAO:0001119
xref: UMLS:C0011646 {source="ncithesaurus:Dermis"}
xref: VHOG:0000108
xref: Wikipedia:Dermis
xref: XAO:0000217
xref: ZFA:0001119
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
is_a: UBERON:0013754 ! integumentary system layer
relationship: composed_primarily_of UBERON:0002384 ! connective tissue
relationship: deep_to UBERON:0001003 ! skin epidermis
relationship: develops_from UBERON:0010083 ! future dermis
relationship: has_part GO:0071953 ! elastic fiber
relationship: has_part UBERON:0011860 ! collection of collagen fibrils
relationship: immediate_transformation_of UBERON:0010083 {evidence="definitional"} ! future dermis
relationship: part_of UBERON:0002097 {source="FMA"} ! skin of body
relationship: superficial_to UBERON:0002072 ! hypodermis
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/23/EpidermisPainted.svg" xsd:anyURI
property_value: editor_note "Consider adding a layer-of-skin grouping class for all skin layers" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A collagenous layer of the skin subjacent to the epidermis and covering the hypodermis. It contains various types of cells (e.g. fibroblasts, pigment cells, nerve, blood vessels and scales. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001119", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "When approaching controversies surrounding skin evolution, we need to remember that the skin consists of two layers, an epidermis and a dermis, not a single evolving structure. (...) It is little wonder that controversies about homology exist. If we think of the epidermis, the dermis, and their interactions as an evolving unit, then their specialized products (hair, feathers, and reptilian scales) are broadly homologous.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000108", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.231-232 see also p.209 and p.228 and Figure 6-1", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "dermal" xsd:string

[Term]
id: UBERON:0002072
name: hypodermis
namespace: uberon
def: "Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]." [Wikipedia:Hypodermis]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "hypoderm" EXACT []
synonym: "sub-tegumental tissue" RELATED [BTO:0004525]
synonym: "subcutaneous tissue" RELATED [Wikipedia:Hypodermis]
synonym: "subcutis" RELATED []
synonym: "subtegumental tissue" RELATED [BTO:0004525]
synonym: "superficial fascia" RELATED INCONSISTENT []
synonym: "tela subcutanea" RELATED OMO:0003011 [Wikipedia:Hypodermis]
synonym: "vertebrate hypodermis" EXACT []
xref: BTO:0001314
xref: CALOHA:TS-2366
xref: EMAPA:37505 {source="MA:th"}
xref: FMA:70544
xref: MESH:D040521 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: NCIT:C33645
xref: TAO:0001136
xref: UMLS:C0278403 {source="ncithesaurus:Subcutis"}
xref: Wikipedia:Hypodermis
xref: ZFA:0001136
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0013754 ! integumentary system layer
relationship: composed_primarily_of UBERON:0001013 ! adipose tissue
relationship: composed_primarily_of UBERON:0011825 {source="FMA-modified"} ! loose connective tissue
relationship: deep_to UBERON:0002067 ! dermis
relationship: part_of UBERON:0002199 {source="ZFA"} ! integument
relationship: superficial_to UBERON:0001015 ! musculature
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001136", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells[FMA:70544]." xsd:string {source="FMA:70544"}
property_value: UBPROP:0000007 "hypodermal" xsd:string
property_value: UBPROP:0000007 "subcutaneous" xsd:string
property_value: UBPROP:0000007 "subcutaneus" xsd:string
property_value: UBPROP:0000012 "BTO has 'subcutis', as part of dermis. We follow FMA in having distinct classes for hypodermis and superficial fascia, and including these as part of the non-skin intgeument." xsd:string {external_ontology="BTO"}

[Term]
id: UBERON:0002075
name: viscus
namespace: uberon
def: "An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen." [BTO:0001491, https://github.com/obophenotype/mouse-anatomy-ontology/issues/14, Wikipedia:Viscus]
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: upper_level
synonym: "splanchnic tissue" RELATED [BTO:0001491]
synonym: "viscera" RELATED []
synonym: "visceral organ" EXACT [RETIRED_EHDAA2:0002201]
synonym: "visceral organ system" EXACT [MA:0000019]
synonym: "visceral tissue" RELATED [BTO:0001491]
xref: AAO:0010386
xref: BTO:0001491
xref: EHDAA:512
xref: EMAPA:16245
xref: FMA:7085
xref: MA:0000019
xref: MESH:D014781
xref: NCIT:C28287
xref: RETIRED_EHDAA2:0002201
xref: SCTID:118760003
xref: UMLS:C0042779 {source="ncithesaurus:Viscera"}
xref: Wikipedia:Viscus
xref: XAO:0003034
is_a: UBERON:0005177 ! trunk region element
intersection_of: UBERON:0000062 ! organ
intersection_of: located_in UBERON:0002323 ! coelemic cavity lumen
relationship: located_in UBERON:0002323 ! coelemic cavity lumen
property_value: UBPROP:0000001 "An internal organ of the body; especially: one (as the heart, liver, or intestine) located in the great cavity of the trunk proper.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010386", ontology="AAO", source="BTO:0001491"}
property_value: UBPROP:0000012 "general anatomical term in FMA. Note that we place the MA class here temporarily, although properly systems should be distinguished from organs." xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0002078
name: right cardiac atrium
namespace: uberon
def: "A cardiac atrium that is in the right side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Right_atrium]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "atrium dextrum" RELATED OMO:0003011 [Wikipedia:Right_atrium]
synonym: "cardiac right atrium" EXACT []
synonym: "heart right atrium" EXACT [MA:0000075]
synonym: "right atrium" EXACT [VHOG:0000328]
synonym: "right atrium of heart" EXACT []
synonym: "right cardiac atrium" EXACT []
xref: AAO:0010248
xref: BTO:0001703
xref: EHDAA2:0000290
xref: EMAPA:17321
xref: FMA:7096
xref: galen:RightAtrium
xref: MA:0000075
xref: NCIT:C12868
xref: SCTID:244383003
xref: UMLS:C0225844 {source="ncithesaurus:Right_Atrium"}
xref: VHOG:0000328
xref: Wikipedia:Right_atrium
xref: XAO:0003192
is_a: UBERON:0002081 ! cardiac atrium
is_a: UBERON:0035554 ! right cardiac chamber
intersection_of: UBERON:0002081 ! cardiac atrium
intersection_of: in_right_side_of UBERON:0000948 ! heart
relationship: connected_to UBERON:0004537 ! blood vasculature
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Right cardiac chamber which is continuous with the superior vena cava and inferior vena cava.[FMA]" xsd:string {source="FMA:7096"}
property_value: UBPROP:0000003 "The tetrapod clade develops a complete atrial septum and loses the fifth aortic arch altogether.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000328", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0002079
name: left cardiac atrium
namespace: uberon
def: "A cardiac atrium that is in the left side of the heart. It receives oxygenated blood from the pulmonary veins, In mammals this is pumped into the left ventricle, via the Mitral valve." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Left_atrium]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "atrium sinistrum" EXACT OMO:0003011 [Wikipedia:Left_atrium]
synonym: "cardiac left atrium" EXACT []
synonym: "heart left atrium" EXACT [MA:0000074]
synonym: "left atrium" EXACT [VHOG:0000369]
synonym: "left atrium of heart" EXACT []
synonym: "left cardiac atrium" EXACT []
xref: AAO:0010247
xref: BTO:0001702
xref: EHDAA2:0000275
xref: EMAPA:17315
xref: FMA:7097
xref: galen:LeftAtrium
xref: MA:0000074
xref: NCIT:C12869
xref: SCTID:244387002
xref: UMLS:C0225860 {source="ncithesaurus:Left_Atrium"}
xref: VHOG:0000369
xref: Wikipedia:Left_atrium
xref: XAO:0003191
is_a: UBERON:0002081 ! cardiac atrium
is_a: UBERON:0035553 ! left cardiac chamber
intersection_of: UBERON:0002081 ! cardiac atrium
intersection_of: in_left_side_of UBERON:0000948 ! heart
relationship: connected_to UBERON:0004537 ! blood vasculature
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Left cardiac chamber which is continuous with the pulmonary venous trunk.[FMA]" xsd:string {source="FMA:7097"}
property_value: UBPROP:0000001 "The chamber of the heart that receives blood from the lungs[XAO:EJS]." xsd:string {source="XAO:EJS"}
property_value: UBPROP:0000003 "The tetrapod clade develops a complete atrial septum and loses the fifth aortic arch altogether.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000369", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0002080
name: heart right ventricle
namespace: uberon
def: "A cardiac ventricle that is in the right side of the heart." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "cardiac right ventricle" EXACT []
synonym: "right cardiac ventricle" RELATED [EMAPA:17340]
synonym: "right ventricle" EXACT [FMA:7098]
synonym: "right ventricle of heart" EXACT []
synonym: "ventriculus dexter" RELATED OMO:0003011 [Wikipedia:Right_ventricle]
xref: BTO:0001630
xref: CALOHA:TS-0443
xref: EHDAA2:0000196
xref: EMAPA:17340
xref: FMA:7098
xref: galen:RightVentricle
xref: MA:0000093
xref: NCIT:C12870
xref: SCTID:244384009
xref: UMLS:C0225883 {source="ncithesaurus:Right_Ventricle"}
xref: VHOG:0000717
xref: Wikipedia:Right_ventricle
is_a: UBERON:0002082 ! cardiac ventricle
is_a: UBERON:0035554 ! right cardiac chamber
intersection_of: UBERON:0002082 ! cardiac ventricle
intersection_of: in_right_side_of UBERON:0000948 ! heart
relationship: connected_to UBERON:0004537 ! blood vasculature
relationship: develops_from UBERON:0009889 {source="PMID:17276708"} ! secondary heart field
relationship: has_developmental_contribution_from UBERON:0004706 {source="cjm"} ! bulbus cordis
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The muscular chamber on the right and in front of the left ventricle. It generally receives venous blood from the right atrium and conveys it into the pulmonary artery. [(1988)_Dorian_AF, Amsterdam, Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B._Anatomy, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier's_Encyclopaedic_Dictionary_of_Medicine][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000717", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI
property_value: UBPROP:0000008 "In mammals continuous with the pulmonary arteries" xsd:string

[Term]
id: UBERON:0002081
name: cardiac atrium
namespace: uberon
def: "Cardiac chamber in which blood enters the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Heart_atrium]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "atria" EXACT OMO:0003004 []
synonym: "atrial tissue" RELATED [BTO:0000903]
synonym: "atrium" EXACT [ZFA:0000471]
synonym: "atrium of heart" EXACT []
synonym: "cardiac atria" EXACT OMO:0003004 []
synonym: "heart atrium" EXACT []
xref: AAO:0010246
xref: BTO:0000903
xref: CALOHA:TS-0437
xref: EFO:0000277
xref: EHDAA2:0000154
xref: EHDAA:1265
xref: EMAPA:16688
xref: EV:0100019
xref: FMA:7099
xref: GAID:555
xref: galen:Atrium
xref: MA:0000073
xref: MAT:0000496
xref: MESH:D006325
xref: NCIT:C12728
xref: SCTID:261405004
xref: TAO:0000471
xref: UMLS:C0018792 {source="ncithesaurus:Cardiac_Atrium"}
xref: VHOG:0000175
xref: Wikipedia:Heart_atrium
xref: ZFA:0000471
is_a: UBERON:0004151 ! cardiac chamber
relationship: contributes_to_morphology_of UBERON:0000948 ! heart
relationship: develops_from UBERON:0010227 ! future cardiac atrium
relationship: immediate_transformation_of UBERON:0010227 ! future cardiac atrium
property_value: UBPROP:0000001 "One of four heart chambers.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000471", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "One of two chambers of the heart which receive blood from the veins and forces it by muscular contration to the ventricle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010246", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "In the primitive vertebrate heart the four chambers are: 1. Sinus venosus (...) 2. Atrium (...) 3. Ventricle (...) 4. Conus arteriosus (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000175", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970) p.428", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002082
name: cardiac ventricle
namespace: uberon
def: "Cardiac chamber through which blood leaves the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Ventricle_(heart)]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "heart ventricle" EXACT []
synonym: "lower chamber of heart" EXACT []
synonym: "ventricle" BROAD []
synonym: "ventricle of heart" EXACT []
xref: AAO:0010249
xref: BTO:0000862
xref: CALOHA:TS-0444
xref: EFO:0000317
xref: EHDAA2:0004164
xref: EHDAA:1912
xref: EMAPA:17331
xref: EV:0100020
xref: FMA:7100
xref: GAID:568
xref: galen:Ventricle
xref: MA:0000091
xref: MAT:0000497
xref: MESH:D006352
xref: NCIT:C12730
xref: SCTID:277699000
xref: TAO:0000009
xref: UMLS:C0018827 {source="ncithesaurus:Cardiac_Ventricle"}
xref: VHOG:0000435
xref: Wikipedia:Ventricle_(heart)
xref: XAO:0003193
xref: ZFA:0000009
is_a: UBERON:0004151 ! cardiac chamber
relationship: contributes_to_morphology_of UBERON:0000948 ! heart
relationship: develops_from UBERON:0006283 ! future cardiac ventricle
relationship: immediate_transformation_of UBERON:0006283 {source="Bgee:AN"} ! future cardiac ventricle
property_value: UBPROP:0000001 "A chamber of the heart that receives blood from one or more atria and pumps it by muscular contraction into the arteries.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010249", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "One of four heart chambers.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000009", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "In the primitive vertebrate heart the four chambers are: 1. Sinus venosus (...) 2. Atrium (...) 3. Ventricle (...) 4. Conus arteriosus (...)[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000435", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970) p.428", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002084
name: heart left ventricle
namespace: uberon
def: "A cardiac ventricle that is in the left side of the heart." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "cardiac left ventricle" EXACT []
synonym: "left cardiac ventricle" EXACT []
synonym: "left ventricle" EXACT [FMA:7101]
synonym: "left ventricle of heart" EXACT []
synonym: "ventriculus sinister cordis" RELATED OMO:0003011 [Wikipedia:Left_ventricle]
xref: BTO:0001629
xref: CALOHA:TS-0439
xref: EHDAA2:0002178
xref: EMAPA:17337
xref: FMA:7101
xref: galen:LeftVentricle
xref: MA:0000092
xref: NCIT:C12871
xref: SCTID:244385005
xref: UMLS:C0225897 {source="ncithesaurus:Left_Ventricle"}
xref: VHOG:0000718
xref: Wikipedia:Left_ventricle
is_a: UBERON:0002082 ! cardiac ventricle
is_a: UBERON:0035553 ! left cardiac chamber
intersection_of: UBERON:0002082 ! cardiac ventricle
intersection_of: in_left_side_of UBERON:0000948 ! heart
relationship: connected_to UBERON:0004537 ! blood vasculature
relationship: continuous_with UBERON:0000947 ! aorta
relationship: develops_from UBERON:0004140 {source="GO"} ! primary heart field
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Thick-walled muscular chamber constituting the left border and apex of the heart. It receives oxygenated blood from the left atrium through the mitral orifice and send it off into the aorta. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000718", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "The vertebrate heart initially forms as a tube from a population of precursor cells termed the first heart field (FHF). Cells from the adjacent second heart field (SHF) are then progressively added to the developing heart. In avian and mammalian hearts, the FHF contributes mainly to the left ventricle, whereas the SHF gives rise to the outflow tract and large portions of the right ventricle and atria. Both fields arise from common mesodermal progenitors, although the detailed lineage relationships between FHF and SHF remain uncertain.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000718", ontology="VHOG", source="DOI:10.1126/science.1190181 Stolfi A, Gainous TB, Young JJ, Mori A, Levine M, Christiaen L, Early chordate origins of the vertebrate second heart field. Science (2010)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI
property_value: UBPROP:0000008 "In mammals continuous with aorta" xsd:string

[Term]
id: UBERON:0002085
name: interatrial septum
namespace: uberon
def: "A cardiac septum that divides the left and right atria of the heart." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: uberon_slim
synonym: "atrial septum" EXACT []
synonym: "atrium septum" EXACT []
synonym: "interatrial septal wall" EXACT []
xref: EHDAA2:0000838
xref: EHDAA:1896
xref: EMAPA:17011
xref: FMA:7108
xref: galen:InteratrialSeptum
xref: MA:0000084
xref: NCIT:C32818
xref: SCTID:362016003
xref: UMLS:C0225836 {source="ncithesaurus:Interatrial_Septum"}
xref: VHOG:0000385
xref: Wikipedia:Interatrial_septum
is_a: UBERON:0002099 ! cardiac septum
intersection_of: UBERON:0002099 ! cardiac septum
intersection_of: adjacent_to UBERON:0002078 ! right cardiac atrium
intersection_of: adjacent_to UBERON:0002079 ! left cardiac atrium
relationship: adjacent_to UBERON:0002078 ! right cardiac atrium
relationship: adjacent_to UBERON:0002079 ! left cardiac atrium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png" xsd:anyURI
property_value: UBPROP:0000001 "The partition separating the right and left atria of the heart. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000385", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/interatrial+septum"}
property_value: UBPROP:0000003 "The tetrapod clade develops a complete atrial septum and loses the fifth aortic arch altogether.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000385", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002090
name: postcranial axial skeleton
namespace: uberon
def: "The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]." [https://sourceforge.net/tracker/?func=detail&aid=2983975&group_id=76834&atid=974957, https://sourceforge.net/tracker/?func=detail&atid=1205376&aid=2983977&group_id=76834, ZFA:0000317]
comment: previous some AOs had used the term 'axial skeleton' to include the skull. This is being resolved (see tracker items above). Status: MA - fixed.
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "axial skeleton" BROAD [FMA:71221, https://github.com/obophenotype/uberon/wiki/The-axial-skeleton]
synonym: "post-cranial axial skeleton" EXACT []
xref: AAO:0000034
xref: EFO:0000942
xref: EHDAA2:0000161
xref: EHDAA:5049
xref: EMAPA:17214
xref: EMAPA:37721 {source="MA:th"}
xref: FMA:71221
xref: MA:0002986
xref: MAT:0000148
xref: MESH:D013131 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: MIAA:0000148
xref: TAO:0000317
xref: VHOG:0000317
xref: VSAO:0000093
xref: XAO:0003073
xref: ZFA:0000317
is_a: UBERON:0010912 ! subdivision of skeleton
relationship: develops_from UBERON:0003089 ! sclerotome
relationship: part_of UBERON:0005944 ! axial skeleton plus cranial skeleton
relationship: part_of UBERON:0011138 ! postcranial axial skeletal system
property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton" xsd:anyURI
property_value: UBPROP:0000001 "Skeletal subdivision of the central body axis including vertebrae, notochord, ribs, and sternum.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000093", ontology="VSAO", source="PSPUB:0000170"}
property_value: UBPROP:0000001 "The axial skeleton is formed by the vertebral column, a metameric, semi-flexible, arched bar located in the dorsal part of the trunk, and is formed by a series of cartilaginous or bony vertebrae. It provides suspension for the appendicular skeleton and protection for the spinal nerve cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000034", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000001 "The post-cranial structural components forming the long axis of the vertebrate body; usually consists of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000317", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "The axial musculoskeletal system represents the plesiomorphic locomotor engine of the vertebrate body, playing a central role in locomotion. In craniates, the evolution of the postcranial skeleton is characterized by two major transformations. First, the axial skeleton became increasingly functionally and morphologically regionalized. Second, the axial-based locomotion plesiomorphic for craniates became progressively appendage-based with the evolution of extremities in tetrapods.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000317", ontology="VHOG", source="DOI:10.1186/1742-9994-8-4 Schilling N, Evolution of the axial system in craniates: morphology and function of the perivertebral musculature. Frontiers in Zoology (2011)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002091
name: appendicular skeleton
namespace: uberon
def: "Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003, Wikipedia:Appendicular_skeleton]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "appendicular skeleton" EXACT []
synonym: "entire appendicular skeleton" EXACT [https://github.com/obophenotype/uberon/issues/59]
synonym: "paired fin skeleton" NARROW SENSU []
synonym: "skeleton appendiculare" RELATED OMO:0003011 [Wikipedia:Appendicular_skeleton]
xref: AAO:0000747
xref: EFO:0000951
xref: EMAPA:32729
xref: FMA:71222
xref: MA:0000290
xref: MAT:0000278
xref: MIAA:0000278
xref: NCIT:C49477
xref: SCTID:322050006
xref: UMLS:C0222646 {source="ncithesaurus:Appendicular_Skeleton"}
xref: VHOG:0001666
xref: VSAO:0000076
xref: Wikipedia:Appendicular_skeleton
xref: XAO:0003166
is_a: UBERON:0010912 ! subdivision of skeleton
relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system
relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata <vertebrates>
relationship: overlaps UBERON:0000026 ! appendage
relationship: part_of UBERON:0011249 ! appendicular skeletal system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/7c/Appendicular_skeleton_diagram.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Appendages-and-the-appendicular-skeleton" xsd:anyURI
property_value: UBPROP:0000001 "Skeletal subdivision consisting of all the skeletal elements in the pectoral and pelvic appendage complexes.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000076", ontology="VSAO", source="PSPUB:0000170", source="https://orcid.org/0000-0002-6601-2165"}
property_value: UBPROP:0000001 "Skeletal system that consists of the paired fins (pectoral or pelvic fins).[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000027", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000001 "The pectoral and pelvic girdles, which articulate with the axial skeleton, together with their associated limbs, the forelimbs and hind limbs, form the appendicular skeleton.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000747", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000012 "ontologies differ in whether they treat the term appendicular skeleton as being the entire set of bones in the limbs, or whether the fore and hind limbs/fins are treated as seperate appendicular skeletons. Here we follow FMA, and treat the appendicular skeleton as the sum total of skeletal elements in the organism (this is evidenced by the fact that in FMA, skeleton of left/right upper/lower limb is part_of a appendicular skeleton, and subtypes of 'subdivision of appendicular skeleton'). We have separate classes such as 'skeleton of limb', and 'skeleton of hindlimb' for the 4 parts of the appendicular skeleton. In future the ZFA/TAO classes may be moved." xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0002094
name: interventricular septum
namespace: uberon
def: "Cardiac septum which separates the right ventricle from the left ventricle.[FMA]." [FMA:7133]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "heart interventricular septum" EXACT [MA:0000085]
synonym: "heart ventricular septum" EXACT [MA:0000085]
synonym: "interventricular septum of heart" RELATED [BTO:0002483]
synonym: "interventriculare cordis" RELATED [BTO:0002483]
synonym: "intraventricular septum" RELATED [Wikipedia:Interventricular_septum]
synonym: "s. interventriculare cordis" RELATED OMO:0003011 [Wikipedia:Interventricular_septum]
synonym: "septum inferius" RELATED [Wikipedia:Interventricular_septum]
synonym: "septum membranaceum" RELATED [Wikipedia:Interventricular_septum]
synonym: "ventricle septum" RELATED []
synonym: "ventricular septum" RELATED [MA:0000085, Wikipedia:Interventricular_septum]
xref: BTO:0002483
xref: EFO:0001956
xref: EHDAA:2603
xref: EMAPA:17333
xref: FMA:7133
xref: galen:InterventricularSeptum
xref: MA:0000085
xref: NCIT:C32874
xref: SCTID:362019005
xref: UMLS:C0225870 {source="ncithesaurus:Interventricular_Septum"}
xref: VHOG:0000386
xref: Wikipedia:Interventricular_septum
is_a: UBERON:0002099 ! cardiac septum
intersection_of: UBERON:0002099 ! cardiac septum
intersection_of: adjacent_to UBERON:0002080 ! heart right ventricle
intersection_of: adjacent_to UBERON:0002084 ! heart left ventricle
relationship: adjacent_to UBERON:0002080 ! heart right ventricle
relationship: adjacent_to UBERON:0002084 ! heart left ventricle
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray498.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The partition separating the right and left ventricles of the heart. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000386", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/interventricular+septum"}
property_value: UBPROP:0000003 "The two most progressive vertebrate classes, the birds and mammals, have completed the ventricular septum and at long last have completely separated the two blood streams along the length of the major heart chambers. This development has obviously been brought about independently in the two cases, since mammals and birds have evolved independently from primitive reptiles.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000386", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970) p.430", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "involves the recruitment of myocardial cells as well as of non- muscular mesenchymal cells (Kaufman and Bard, 1999)" xsd:string {source="ISBN:0124020607"}

[Term]
id: UBERON:0002095
name: mesentery
namespace: uberon
def: "Anatomical organ component composed of a double layer of serous membrane that suspends a viscus from the body wall or connects adjacent viscera and in doing so conveys blood vessels, lymphatics and nerves to and from the viscera. Examples: greater omentum, broad ligament of uterus, sigmoid mesocolon." [FMA:7144, https://github.com/obophenotype/uberon/issues/85, Wikipedia:Mesentery, Wikipedia:Mesentery#Mesentery_.28general.29]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "generic mesentery" EXACT [Wikipedia:Mesentery]
synonym: "mesentery (generic)" EXACT [Wikipedia:Mesentery]
xref: AAO:0011061
xref: BTO:0001380
xref: EV:0100083
xref: FMA:7144
xref: GAID:21
xref: galen:Mesentery
xref: MESH:D008643
xref: NCIT:C33103
xref: SCTID:362707009
xref: UMLS:C0025474 {source="ncithesaurus:Mesentery"}
xref: Wikipedia:Mesentery#Mesentery_.28general.29
is_a: UBERON:0000042 ! serous membrane
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/19/Gray1038.png" xsd:anyURI
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: UBPROP:0000007 "mesenteric" xsd:string
property_value: UBPROP:0000012 "in Uberon, this term is used in the generic sense, not necessarily restricted to the peritoneum, consistent with FMA. WP: 'In anatomy, the mesentery is the double layer of peritoneum that suspends the jejunum and ileum from the posterior wall of the abdomen. Its meaning, however, is frequently extended to include double layers of peritoneum connecting various components of the abdominal cavity.'. TODO - check. Consider FMA:259286 - Region of mesentery." xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0002097
name: skin of body
namespace: uberon
def: "The organ covering the body that consists of the dermis and epidermis." [UBERON:cjm]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: pheno_slim
subset: uberon_slim
synonym: "entire integument" RELATED []
synonym: "entire skin" EXACT []
synonym: "integument" RELATED []
synonym: "integumental organ" RELATED []
synonym: "pelt" RELATED []
synonym: "skin" RELATED []
synonym: "skin organ" EXACT []
xref: BTO:0001253
xref: CALOHA:TS-0934
xref: EFO:0000962
xref: EHDAA2:0001844
xref: EMAPA:17525
xref: FMA:7163
xref: galen:Skin
xref: MESH:D012867
xref: MFMO:0000099
xref: NCIT:C12470
xref: SCTID:181469002
xref: UMLS:C1123023 {source="ncithesaurus:Skin"}
xref: Wikipedia:Skin
xref: XAO:0000023
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000062 ! organ
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: composed_primarily_of UBERON:0000014 ! zone of skin
relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! embryonic skin basal layer
relationship: part_of UBERON:0002199 ! integument
property_value: curator_notes "consider 'integumentary system' for invertebrates" xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Skin.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_M_Skin.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Skin.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.3/3d-vh-f-skin.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "MA uses the term skin to refer to what is called here: zone of skin" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0002099
name: cardiac septum
namespace: uberon
def: "The thin membranous structure between the two heart atria or the thick muscular structure between the two heart ventricles." [MESH:A07.541.459]
subset: pheno_slim
subset: uberon_slim
synonym: "cardiac septa" EXACT OMO:0003004 []
synonym: "heart septa" EXACT OMO:0003004 []
synonym: "heart septum" EXACT []
synonym: "septum of heart" EXACT []
synonym: "spiral septa" RELATED OMO:0003004 [XAO:0004141]
xref: EMAPA:35400
xref: FMA:7180
xref: GAID:562
xref: MA:0000083
xref: MESH:D006346
xref: NCIT:C49485
xref: SCTID:362014000
xref: UMLS:C0018819 {source="ncithesaurus:Heart_Septum"}
is_a: UBERON:0003037 ! septum
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0003037 ! septum
intersection_of: part_of UBERON:0000948 ! heart
relationship: adjacent_to UBERON:0004151 ! cardiac chamber
relationship: contributes_to_morphology_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart
property_value: UBPROP:0000008 "'Terrestrial vertebrates have divided hearts in which septae separate the oxygenated and deoxygenated blood within the pulmonary and systemic circulations'" xsd:string
property_value: UBPROP:0000012 "in GO, septum morphogenesis is part of cardiac chamber morphogenesis; need to add axioms to infer this" xsd:string {external_ontology="GO"}

[Term]
id: UBERON:0002100
name: trunk
namespace: uberon
def: "Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present." [TAO:0001115, UBERONREF:0000006, Wikipedia:Torso]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "Rumpf" RELATED [BTO:0001493]
synonym: "thoracolumbar region" EXACT []
synonym: "torso" EXACT []
synonym: "trunk region" EXACT [XAO:0000054]
xref: AAO:0010339
xref: BILA:0000116
xref: BTO:0001493
xref: CALOHA:TS-1071
xref: EFO:0000966
xref: EMAPA:31857
xref: FMA:7181
xref: galen:Trunk
xref: MA:0000004
xref: MAT:0000296
xref: MIAA:0000296
xref: NCIT:C33816
xref: SCTID:262225004
xref: TAO:0001115
xref: UMLS:C0460005 {source="ncithesaurus:Trunk"}
xref: Wikipedia:Torso
xref: XAO:0000054
xref: XAO:0003025
xref: ZFA:0001115
is_a: UBERON:0011676 ! subdivision of organism along main body axis
relationship: has_part UBERON:0000915 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! thoracic segment of trunk
relationship: has_part UBERON:0000916 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! abdomen
relationship: part_of UBERON:0013702 ! body proper
property_value: RO:0002171 UBERON:0000026 {exceptions="ZFA", source="https://github.com/obophenotype/uberon/issues/378", status="pending"}
property_value: RO:0002171 UBERON:0000033
property_value: UBPROP:0000001 "Organism subdivision that is the part of the body posterior to the head and anterior to the tail.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010339", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "Organism subdivision which is the part of the body posterior to the head and anterior to the tail.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001115", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0002104
name: visual system
namespace: uberon
alt_id: UBERON:0007036
def: "The sensory system subserving the sense of vision." [NIFSTD:FMAID_7191]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "photosensory system" EXACT [BILA:0000140]
synonym: "visual organ system" EXACT []
xref: AAO:0000632
xref: BILA:0000140
xref: EMAPA:36003
xref: FMA:7191
xref: http://uri.neuinfo.org/nif/nifstd/FMAID_7191
xref: MA:0002444
xref: NCIT:C12888
xref: SCTID:281831001
xref: TAO:0001127
xref: UMLS:C0587900 {source="ncithesaurus:Visual_System"}
xref: Wikipedia:Visual_system
xref: XAO:0003198
xref: ZFA:0001127
is_a: UBERON:0001032 ! sensory system
relationship: capable_of_part_of GO:0007601 ! visual perception
property_value: UBPROP:0000001 "The sensory system used for sight.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000632", ontology="AAO", source="AAO:EJS"}

[Term]
id: UBERON:0002105
name: vestibulo-auditory system
namespace: uberon
def: "Sensory system responsible for the perception of spatial orientation and auditory stimuli." [ZFA:0001138]
subset: functional_classification
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "auditory organ system" EXACT []
synonym: "auditory system" RELATED []
synonym: "auditory/vestibular system" RELATED []
synonym: "vestibuloauditory system" EXACT []
synonym: "vestibuloauditory system" RELATED []
xref: AAO:0000631
xref: EMAPA:36002
xref: EMAPA:37985 {source="MA:th"}
xref: FMA:78500
xref: TAO:0001138
xref: XAO:0003195
xref: ZFA:0001138
is_a: UBERON:0001032 ! sensory system
relationship: capable_of_part_of GO:0007605 ! sensory perception of sound
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d2/Anatomy_of_the_Human_Ear.svg" xsd:anyURI
property_value: UBPROP:0000001 "The sensory system used for balance and hearing.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000631", ontology="AAO", source="AAO:EJS"}

[Term]
id: UBERON:0002106
name: spleen
namespace: uberon
def: "The organ that functions to filter blood and to store red corpuscles and platelets." [ISBN:0-683-40008-8, MP:0000689]
subset: efo_slim
subset: human_reference_atlas
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "lien" RELATED OMO:0003011 [Wikipedia:Spleen]
xref: AAO:0010395
xref: BTO:0001281
xref: CALOHA:TS-0956
xref: EFO:0000869
xref: EMAPA:18767
xref: EV:0100055
xref: FMA:7196
xref: GAID:1289
xref: galen:Spleen
xref: MA:0000141
xref: MAT:0000085
xref: MESH:D013154
xref: MIAA:0000085
xref: NCIT:C12432
xref: SCTID:181279003
xref: TAO:0000436
xref: UMLS:C0037993 {source="ncithesaurus:Spleen"}
xref: VHOG:0000120
xref: Wikipedia:Spleen
xref: XAO:0000328
xref: ZFA:0000436
is_a: UBERON:0004177 ! hemopoietic organ
is_a: UBERON:0005057 ! immune organ
is_a: UBERON:0017672 ! abdominal viscera
relationship: develops_from UBERON:0006293 ! spleen primordium
relationship: only_in_taxon NCBITaxon:7776 {source="multiple sources - true spleen appear in jawed vertebrates"} ! Gnathostomata <vertebrates>
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Spleen.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Spleen.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spleen.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "An organ involved in red blood cell filtration and immune response.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010395", ontology="AAO", source="AAO:BMZ"}
property_value: UBPROP:0000003 "With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000120", ontology="VHOG", source="ISBN:978-0781765190 Paul WE, Fundamental Immunology (2008) p.94", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "lienal" xsd:string
property_value: UBPROP:0000007 "splenic" xsd:string
property_value: UBPROP:0000008 "In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron" xsd:string
property_value: UBPROP:0000008 "Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96)" xsd:string {source="PMID:20959416"}
property_value: UBPROP:0000009 "It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells" xsd:string

[Term]
id: UBERON:0002107
name: liver
namespace: uberon
def: "An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]." [BTO:0000759, Wikipedia:Liver]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "iecur" RELATED OMO:0003011 [Wikipedia:Liver]
synonym: "jecur" RELATED OMO:0003011 [Wikipedia:Liver]
xref: AAO:0010111
xref: BTO:0000759
xref: CALOHA:TS-0564
xref: EFO:0000887
xref: EHDAA2:0000997
xref: EHDAA:2197
xref: EMAPA:16846
xref: EV:0100089
xref: FMA:7197
xref: GAID:288
xref: galen:Liver
xref: MA:0000358
xref: MAT:0000097
xref: MESH:D008099
xref: MIAA:0000097
xref: NCIT:C12392
xref: SCTID:181268008
xref: TAO:0000123
xref: UMLS:C0023884 {source="ncithesaurus:Liver"}
xref: VHOG:0000257
xref: Wikipedia:Liver
xref: XAO:0000133
xref: ZFA:0000123
is_a: UBERON:0002365 {source="BTO", source="EHDAA2", source="GO-def"} ! exocrine gland
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0005172 ! abdomen element
is_a: UBERON:0006925 ! digestive system gland
relationship: contributes_to_morphology_of UBERON:0002423 ! hepatobiliary system
relationship: develops_from UBERON:0004161 {source="EHDAA2"} ! septum transversum
relationship: develops_from UBERON:0008836 {source="http://www.stembook.org/node/512"} ! liver bud
relationship: has_part UBERON:0004647 ! liver lobule
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: overlaps UBERON:0002405 {source="ZFA-weakened"} ! immune system
relationship: part_of UBERON:0002423 {source="ZFA"} ! hepatobiliary system
relationship: produces UBERON:0001970 ! bile
relationship: site_of GO:0002384 ! hepatic immune response
relationship: site_of GO:0005978 ! glycogen biosynthetic process
relationship: site_of GO:0005980 ! glycogen catabolic process
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Liver.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Liver.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/6/64/Leber_Schaf.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Organ which secretes bile and participates in formation of certain blood proteins.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010111", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000002 "relationship type change: differentiates_from endoderm (AAO:0000139) CHANGED TO: develops_from endoderm (UBERON:0000925)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010111", ontology="AAO"}
property_value: UBPROP:0000003 "All vertebrates possess a liver (reference 1); Later in craniate evolution, an anterior gill arch was transformed into jaws, and many new types of feeding subsequently evolved.(...) A liver evolved that, among its many functions, stores considerable energy as glycogen or lipid (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000257", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.526, ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "hepatic" xsd:string
property_value: UBPROP:0000008 "An organ sometimes referred to as a liver is found associated with the digestive tract of the primitive chordate Amphioxus. However, this is an enzyme secreting gland, not a metabolic organ, and it is unclear how truly homologous it is to the vertebrate liver. The zebrafish liver differs from the mammalian liver in that the hepatocytes are not clearly organized in cords or lobules and the typical portal triads are not apparent. In addition, the zebrafish liver does not have Kuppfer cells. Furthermore, a clear distinction can be made between the male and female liver in the adult zebrafish. The female hepatocytes are very basophilic (Figure 15c) as a result of the production of vitellogenin (Van der Ven et al. 2003)." xsd:string
property_value: UBPROP:0000008 "The liver is found in all vertebrates, and is typically the largest visceral organ. Its form varies considerably in different species, and is largely determined by the shape and arrangement of the surrounding organs. Nonetheless, in most species it is divided into right and left lobes; exceptions to this general rule include snakes, where the shape of the body necessitates a simple cigar-like form. The internal structure of the liver is broadly similar in all vertebrates." xsd:string
property_value: UBPROP:0000009 "secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]." xsd:string
property_value: UBPROP:0000012 "Only ZFA considers this part_of immune system - we weaken this to an overlaps relation, as in general it's only a subset of cells that have clear immune function." xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0002108
name: small intestine
namespace: uberon
def: "Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]." [ISBN:0073040584, Wikipedia:Small_intestine]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "anterior intestine" RELATED []
synonym: "intestinum tenue" RELATED OMO:0003011 [BTO:0000651, Wikipedia:Small_intestine]
synonym: "mid intestine" RELATED []
synonym: "small bowel" EXACT []
synonym: "small intestine" EXACT []
xref: AAO:0010397
xref: BTO:0000651
xref: CALOHA:TS-0942
xref: EFO:0000841
xref: EMAPA:32834
xref: EV:0100072
xref: FMA:7200
xref: GAID:313
xref: galen:SmallIntestine
xref: MA:0000337
xref: MAT:0000047
xref: MESH:D007421
xref: MIAA:0000047
xref: NCIT:C12386
xref: SCTID:181250005
xref: TAO:0001323
xref: UMLS:C0021852 {source="ncithesaurus:Small_Intestine"}
xref: VHOG:0000055
xref: Wikipedia:Small_intestine
xref: XAO:0000130
xref: ZFA:0001323
is_a: UBERON:0004921 {order="2", source="cjm"} ! subdivision of digestive tract
is_a: UBERON:0013765 ! digestive system element
relationship: contributes_to_morphology_of UBERON:0000160 ! intestine
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0000160 ! intestine
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/82/Stomach_colon_rectum_diagram.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Small_Intestine.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Small_Intestine.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The terminal region of the mid intestine is comprised of specialized enterocytes that appear to play a role in mucosal immunity. Wallace et al, 2005.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001323", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "Intestinal surface area also is increased in amphibians and reptiles by internal folds and occasionally by a few villi. The intestine can be divided into a small intestine and a slightly wider large intestine.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000055", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.566", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002110
name: gallbladder
namespace: uberon
def: "An organ that aids digestion and stores bile produced by the liver[WP]." [Wikipedia:Gallbladder]
comment: Rats do not have a gallbladder, but produce bile. The bile flows directly from the liver through the (hepatic) bile duct into the small intestine (Hebel and Stromberg, 1988)
subset: efo_slim
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cholecyst" EXACT [WikipediaVersioned:Gallbladder&oldid=1092217922]
synonym: "gall bladder" EXACT []
synonym: "vesica biliaris" RELATED OMO:0003011 [Wikipedia:Gallbladder]
synonym: "vesica fellea" RELATED OMO:0003011 [Wikipedia:Gallbladder]
xref: AAO:0010114
xref: BTO:0000493
xref: CALOHA:TS-0394
xref: EFO:0000853
xref: EHDAA2:0000699
xref: EHDAA:8062
xref: EMAPA:17202
xref: EV:0100090
xref: FMA:7202
xref: galen:Gallbladder
xref: MA:0000356
xref: MAT:0000072
xref: MESH:D005704
xref: MIAA:0000072
xref: NCIT:C12377
xref: SCTID:181269000
xref: TAO:0000208
xref: UMLS:C0016976 {source="ncithesaurus:Gallbladder"}
xref: VHOG:0000221
xref: Wikipedia:Gallbladder
xref: XAO:0000135
xref: ZFA:0000208
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0013765 ! digestive system element
is_a: UBERON:0017672 ! abdominal viscera
is_a: UBERON:0018707 {source="BTO"} ! bladder organ
relationship: contributes_to_morphology_of UBERON:0001173 ! biliary tree
relationship: develops_from UBERON:0004912 ! biliary bud
relationship: develops_from UBERON:0006242 {evidence="definitional"} ! gallbladder primordium
relationship: part_of UBERON:0002294 ! biliary system
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/b/b1/GallbladderAnatomy-en.svg" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/f/f4/Abdomal_organs.svg" xsd:anyURI
property_value: RO:0002161 NCBITaxon:10114 {source="ISBN:9780120749034"}
property_value: RO:0002161 NCBITaxon:8801 {source="GOC:mr", source="ISBN:9781840761122"}
property_value: RO:0002161 NCBITaxon:8930 {source="GOC:mr", source="ISBN:9781840761122"}
property_value: UBPROP:0000001 "Membranous muscular sac in which the bile from the liver remains stored until it is required. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000221", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000001 "Organ attached to the liver which stores bile and empties into the duodenum via the bile duct as needed for digestion.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010114", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000002 "relationship type change: differentiates_from endoderm (AAO:0000139) CHANGED TO: develops_from endoderm (UBERON:0000925)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010114", ontology="AAO"}
property_value: UBPROP:0000003 "The presence of a gallbladder appears to be a primitive trait. It is found in most fish and all adult reptiles and amphibians and has been well conserved in mammals, for the most part.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000221", ontology="VHOG", source="DOI:10.1002/(SICI)1097-0029(19970915)38:6<571::AID-JEMT3>3.0.CO;2-I Oldham-Ott CK, Gilloteaux J, Comparative morphology of the gallbladder and biliary tract in vertebrates: Variation in structure, homology in function and gallstones. Microscopy research and technique (1997)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002111
name: artery smooth muscle tissue
namespace: uberon
def: "A portion of smooth muscle tissue that is part of an artery [Automatically generated definition]." [OBOL:automatic]
synonym: "arterial smooth muscle" EXACT [BTO:0000087]
synonym: "arterial smooth muscle cell" RELATED [BTO:0000087]
synonym: "artery smooth muscle" EXACT []
synonym: "artery smooth muscle tissue" EXACT []
synonym: "smooth muscle of artery" EXACT [FMA:72024]
xref: BTO:0000087
xref: CALOHA:TS-1198
xref: EMAPA:36285
xref: FMA:72024
xref: MA:0000708
xref: NCIT:C49195
xref: UMLS:C1706851 {source="ncithesaurus:Artery_Smooth_Muscle_Tissue"}
is_a: UBERON:0004237 ! blood vessel smooth muscle
is_a: UBERON:0004695 ! arterial system smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001637 ! artery
relationship: part_of UBERON:0001637 ! artery

[Term]
id: UBERON:0002112
name: smooth muscle of esophagus
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "esophageal smooth muscle" EXACT []
synonym: "esophagus involuntary muscle" EXACT [OBOL:automatic]
synonym: "esophagus non-striated muscle" EXACT [OBOL:automatic]
synonym: "esophagus smooth muscle" EXACT []
synonym: "esophagus smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "gullet involuntary muscle" EXACT [OBOL:automatic]
synonym: "gullet non-striated muscle" EXACT [OBOL:automatic]
synonym: "gullet smooth muscle" EXACT [OBOL:automatic]
synonym: "gullet smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "involuntary muscle of esophagus" EXACT [OBOL:automatic]
synonym: "involuntary muscle of gullet" EXACT [OBOL:automatic]
synonym: "involuntary muscle of oesophagus" EXACT [OBOL:automatic]
synonym: "non-striated muscle of esophagus" EXACT [OBOL:automatic]
synonym: "non-striated muscle of gullet" EXACT [OBOL:automatic]
synonym: "non-striated muscle of oesophagus" EXACT [OBOL:automatic]
synonym: "oesophagus involuntary muscle" EXACT [OBOL:automatic]
synonym: "oesophagus non-striated muscle" EXACT [OBOL:automatic]
synonym: "oesophagus smooth muscle" RELATED []
synonym: "oesophagus smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "smooth muscle of gullet" EXACT [OBOL:automatic]
synonym: "smooth muscle of oesophagus" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of esophagus" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of gullet" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of oesophagus" EXACT [OBOL:automatic]
xref: EMAPA:35323
xref: FMA:72025
xref: MA:0001573
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: contributes_to_morphology_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0003832 ! esophagus muscle

[Term]
id: UBERON:0002113
name: kidney
namespace: uberon
def: "A paired organ of the urinary tract that produces urine and maintains bodily fluid homeostasis, blood pressure, pH levels, red blood cell production and skeleton mineralization." [http://anatomy.uams.edu/anatomyhtml/kidney.html, https://www.kidney.org/kidneydisease/top-5-jobs-kidneys-do, PMID:25140012, PMID:35003210, Wikipedia:Kidney]
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "reniculate kidney" NARROW SENSU [Wikipedia:Reniculate_kidney]
xref: AAO:0000250
xref: BTO:0000671
xref: CALOHA:TS-0510
xref: EFO:0000929
xref: EMAPA:17373
xref: EV:0100096
xref: FMA:7203
xref: GAID:423
xref: galen:Kidney
xref: MA:0000368
xref: MAT:0000119
xref: MESH:D007668
xref: MIAA:0000119
xref: NCIT:C12415
xref: SCTID:181414000
xref: UMLS:C0022646 {source="ncithesaurus:Kidney"}
xref: Wikipedia:Kidney
xref: XAO:0003267
is_a: UBERON:0000489 ! cavitated compound organ
is_a: UBERON:0005172 ! abdomen element
is_a: UBERON:0015212 ! lateral structure
relationship: contributes_to_morphology_of UBERON:0001008 ! renal system
relationship: develops_from UBERON:0003918 {evidence="definitional"} ! kidney mesenchyme
relationship: develops_from UBERON:0005095 ! kidney rudiment
relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0011143 {source="FMA"} ! upper urinary tract
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-7655-4833
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-2804-127X
property_value: RO:0002171 UBERON:0000160
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "One of either of a pair of structures lying on either side of the dorsal aorta in which fluid balance is regulated and waste is excreted out in the form of urine.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000250", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000007 "renal" xsd:string
property_value: UBPROP:0000202 FMA:264815

[Term]
id: UBERON:0002114
name: duodenum
namespace: uberon
def: "The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one)." [ISBN:0815318960, Wikipedia:Duodenum]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "proximal intestine" RELATED [BTO:0000365]
synonym: "upper intestine" RELATED [BTO:0000365]
xref: AAO:0010402
xref: BTO:0000365
xref: CALOHA:TS-0214
xref: EFO:0000851
xref: EMAPA:18852
xref: EV:0100073
xref: FMA:7206
xref: GAID:284
xref: galen:Duodenum
xref: MA:0000338
xref: MAT:0000044
xref: MESH:D004386
xref: MIAA:0000044
xref: NCIT:C12263
xref: SCTID:181247007
xref: UMLS:C0013303 {source="ncithesaurus:Duodenum"}
xref: VHOG:0000052
xref: Wikipedia:Duodenum
xref: XAO:0000236
is_a: UBERON:0004921 {order="3", source="cjm"} ! subdivision of digestive tract
relationship: continuous_with UBERON:0001166 ! pylorus
relationship: contributes_to_morphology_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0002108 ! small intestine
relationship: proximalmost_part_of UBERON:0002108 ! small intestine
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b3/Tractus_intestinalis_duodenum.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Small_Intestine.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Small_Intestine.glb" xsd:anyURI
property_value: RO:0002161 NCBITaxon:7955 {source="ZFA:0000348"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The fixed portion of the small intestine deeply lodged in the posterior wall of the abdomen and extending from the pylorus to the beginning of the jejunum. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000052", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "duodenal" xsd:string
property_value: UBPROP:0000008 "In fish, the divisions of the small intestine are not as clear, and the terms anterior intestine or proximal intestine may be used instead of duodenum." xsd:string {scope="NCBITaxon:32443", source="Wikipedia:Duodenum"}
property_value: UBPROP:0000008 "In humans, the duodenum is a hollow jointed tube about 10-15 inches (25-38 centimetres) long connecting the stomach to the jejunum. It begins with the duodenal bulb and ends at the ligament of Treitz." xsd:string {scope="NCBITaxon:9606", source="Wikipedia:Duodenum"}

[Term]
id: UBERON:0002118
name: right ovary
namespace: uberon
def: "An ovary that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:37367 {source="MA:th"}
xref: FMA:7213
xref: MA:0001705
xref: NCIT:C33487
xref: SCTID:280123002
xref: UMLS:C0227873 {source="ncithesaurus:Right_Ovary"}
is_a: UBERON:0000992 ! ovary
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0000992 ! ovary
intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism
relationship: in_right_side_of UBERON:0000468 ! multicellular organism
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0002119
name: left ovary
namespace: uberon
def: "An ovary that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:37366 {source="MA:th"}
xref: FMA:7214
xref: MA:0001704
xref: NCIT:C32969
xref: SCTID:280124008
xref: UMLS:C0227874 {source="ncithesaurus:Left_Ovary"}
is_a: UBERON:0000992 ! ovary
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0000992 ! ovary
intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI
property_value: UBPROP:0000008 "In some elasmobranchs, the left ovary does not mature, with only the right ovary fully developing. In the primitive jawless fish, and some teleosts, there is only one ovary, formed by the fusion of the paired organs in the embryo" xsd:string {source="Wikipedia:Ovary#In_other_animals"}

[Term]
id: UBERON:0002120
name: pronephros
namespace: uberon
alt_id: UBERON:0005794
def: "In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]." [GO:0048793, Wikipedia:Pronephros]
comment: Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104
subset: efo_slim
subset: organ_slim
subset: uberon_slim
synonym: "archinephron" RELATED [BTO:0001541]
synonym: "embryonic kidney" RELATED [BTO:0001541]
synonym: "pronephric kidney" EXACT [XAO:0002000]
synonym: "pronephron" RELATED [BTO:0001541]
xref: AAO:0011089
xref: BTO:0001541
xref: EFO:0000927
xref: EHDAA2:0001570
xref: EHDAA:1017
xref: EMAPA:16579
xref: FMA:72170
xref: MAT:0000117
xref: MESH:D060910 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: MIAA:0000117
xref: NCIT:C34280
xref: SCTID:308804007
xref: TAO:0000151
xref: UMLS:C0231048 {source="ncithesaurus:Pronephros"}
xref: VHOG:0000037
xref: Wikipedia:Pronephros
xref: XAO:0002000
xref: ZFA:0000151
is_a: UBERON:0002113 {source="GO"} ! kidney
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005423 ! developing anatomical structure
relationship: develops_from UBERON:0005721 {source="ZFA"} ! pronephric mesoderm
relationship: develops_from UBERON:0005754 ! rostral part of nephrogenic cord
relationship: located_in UBERON:0003887 {source="OG"} ! intraembryonic coelom
property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the anterior region of the nephric ridge; forms only as a transient embryonic structure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.748][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000037", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000001 "Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011089", ontology="AAO", source="XAO:curator"}
property_value: UBPROP:0000001 "The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000151", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000037", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.637", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "pronephric" xsd:string

[Term]
id: UBERON:0002128
name: superior olivary complex
namespace: uberon
def: "A collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system." [ISBN:0-19-502694-2, Wikipedia:Superior_olivary_complex]
subset: uberon_slim
synonym: "nucleus olivaris superior" EXACT OMO:0003011 [FMA:72247, FMA:TA]
synonym: "regio olivaris superioris" RELATED OMO:0003011 [NeuroNames:569]
synonym: "superior olivary nuclei" EXACT [FMA:72247]
synonym: "superior olivary nucleus" RELATED INCONSISTENT [FMA:72247]
synonym: "superior olivary nucleus (Barr & Kiernan)" RELATED [NeuroNames:569]
synonym: "superior olive" RELATED INCONSISTENT [FMA:72247, ISBN:0-19-502694-2]
xref: BAMS:SOC
xref: BIRNLEX:1307
xref: DHBA:12462
xref: EMAPA:35840
xref: EV:0100263
xref: FMA:72247
xref: HBA:9177
xref: MA:0001026
xref: MBA:398
xref: MESH:D065832 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: neuronames:569 {source="BIRNLEX:1307"}
xref: UMLS:C0175427 {source="BIRNLEX:1307"}
xref: VHOG:0001381
xref: Wikipedia:Superior_olivary_complex
is_a: UBERON:0007245 ! nuclear complex of neuraxis
is_a: UBERON:0019263 ! gray matter of hindbrain
relationship: part_of UBERON:0003023 {source="NIFSTD"} ! pontine tegmentum
relationship: part_of UBERON:0016490 ! auditory system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/46/Gray713.png" xsd:anyURI
property_value: RO:0002171 UBERON:0002597 {source="ABA"}
property_value: RO:0002171 UBERON:0006840 {source="ABA"}
property_value: RO:0002171 UBERON:0007634 {source="ABA"}
property_value: UBPROP:0000008 "In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound[GO:0021718]" xsd:string
property_value: UBPROP:0000008 "The SOC displays a significant interspecies variation, being largest in bats and rodents and smaller in primates." xsd:string

[Term]
id: UBERON:0002148
name: locus ceruleus
namespace: uberon
def: "The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]." [GAID:577, GO:0021703, Wikipedia:Locus_ceruleus]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "blue nucleus" EXACT [BIRNLEX:905]
synonym: "caerulean nucleus" EXACT []
synonym: "loci coeruleus" RELATED OMO:0003004 [ZFA:0000539]
synonym: "locus caeruleus" EXACT [BIRNLEX:905]
synonym: "locus cinereus" RELATED [BTO:0001408]
synonym: "locus coeruleu" EXACT []
synonym: "locus coeruleus" EXACT []
synonym: "locus coeruleus (Vicq d'Azyr)" RELATED [NeuroNames:583]
synonym: "Noradrenergic cell group A6" EXACT [Noradrenergic_cell_group_A6&oldid=981960774]
synonym: "nucleus caeruleus" EXACT OMO:0003011 [FMA:72478, FMA:TA]
synonym: "nucleus loci caerulei" RELATED OMO:0003011 [NeuroNames:583]
synonym: "nucleus of locus caeruleus" EXACT []
synonym: "nucleus pigmentosus pontis" EXACT [BIRNLEX:905]
synonym: "substantia ferruginea" EXACT [BIRNLEX:905]
xref: BAMS:CAE
xref: BAMS:LC
xref: BIRNLEX:905
xref: BM:Pons-LC
xref: BTO:0001408
xref: DHBA:12819
xref: DMBA:16972
xref: EFO:0001963
xref: EMAPA:35502
xref: FMA:72478
xref: GAID:577
xref: HBA:9148
xref: MA:0001017
xref: MBA:147
xref: MESH:D008125
xref: NCIT:C97333
xref: neuronames:583 {source="BIRNLEX:905"}
xref: SCTID:369016004
xref: TAO:0000539
xref: UMLS:C0023951 {source="ncithesaurus:Locus_Coeruleus", source="BIRNLEX:905"}
xref: Wikipedia:Locus_ceruleus
xref: ZFA:0000539
is_a: UBERON:0006331 ! brainstem nucleus
is_a: UBERON:0009662 ! hindbrain nucleus
is_a: UBERON:8440015 ! noradrenergic cell groups
relationship: capable_of GO:0048243 ! norepinephrine secretion
relationship: part_of UBERON:0003023 {notes="check ZFA", source="NIFSTD"} ! pontine tegmentum
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/77/Gray709.png" xsd:anyURI
property_value: editor_note "TODO - check ZFA/pons. also GO says part of dorsorostral pons" xsd:string
property_value: RO:0002171 UBERON:0002047 {source="ABA"}
property_value: RO:0002171 UBERON:0002267 {source="ABA"}
property_value: RO:0002171 UBERON:0002587 {source="ABA"}
property_value: RO:0002171 UBERON:0003004 {source="ABA"}

[Term]
id: UBERON:0002149
name: superior salivatory nucleus
namespace: uberon
def: "Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703)." [BIRNLEX:1131]
subset: uberon_slim
synonym: "nucleus salivarius superior" RELATED OMO:0003011 [NeuroNames:590]
synonym: "nucleus salivatorius cranialis" RELATED OMO:0003011 [NeuroNames:590]
synonym: "nucleus salivatorius rostralis" RELATED OMO:0003011 [NeuroNames:590]
synonym: "nucleus salivatorius superior" RELATED OMO:0003011 [NeuroNames:590]
synonym: "superior salivary nucleus" EXACT [GO:0021753]
xref: BAMS:SSN
xref: BAMS:SuS
xref: BIRNLEX:1131
xref: DHBA:12435
xref: EHDAA2:0004646
xref: EMAPA:37756 {source="MA:th"}
xref: FMA:72482
xref: HBA:9194
xref: MA:0001027
xref: MBA:462
xref: neuronames:590 {source="BIRNLEX:1131"}
xref: SCTID:369028007
xref: UMLS:C0175447 {source="BIRNLEX:1131"}
xref: Wikipedia:Superior_salivatory_nucleus
is_a: UBERON:0000126 ! cranial nerve nucleus
is_a: UBERON:0004133 ! salivatory nucleus
is_a: UBERON:0007635 ! nucleus of medulla oblongata
relationship: develops_from UBERON:0010125 ! future superior salivatory nucleus
relationship: immediate_transformation_of UBERON:0010125 {evidence="definitional"} ! future superior salivatory nucleus
relationship: part_of UBERON:0003023 ! pontine tegmentum
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6b/Gray788.png" xsd:anyURI
property_value: RO:0002171 UBERON:0002143 {source="ABA"}
property_value: RO:0002171 UBERON:0002147 {source="ABA"}
property_value: RO:0002171 UBERON:0002151 {source="ABA"}
property_value: RO:0002171 UBERON:0002633 {source="ABA"}
property_value: RO:0002171 UBERON:0002682 {source="ABA"}
property_value: RO:0002171 UBERON:0002963 {source="ABA"}
property_value: RO:0002171 UBERON:0002968 {source="ABA"}
property_value: RO:0002171 UBERON:0003011 {source="ABA"}
property_value: RO:0002171 UBERON:0007632 {source="ABA"}

[Term]
id: UBERON:0002165
name: endocardium
namespace: uberon
alt_id: UBERON:0006225
def: "The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]." [GO:0003157]
comment: fixed in GO to reflect FMA. See email to David/Varsha June 18 2010
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "endocardial lining" EXACT [EMAPA:32686]
synonym: "endocardial tissue" EXACT [EMAPA:17868]
synonym: "heart endocardial tissue" RELATED [VHOG:0000084]
synonym: "heart endocardium" EXACT []
xref: AAO:0010408
xref: BTO:0000387
xref: CALOHA:TS-2075
xref: EFO:0000821
xref: EHDAA2:0004153
xref: EMAPA:17868
xref: EMAPA:32686
xref: EV:0100021
xref: FMA:7280
xref: GAID:550
xref: galen:Endocardium
xref: MA:0000076
xref: MAT:0000455
xref: MESH:D004699
xref: NCIT:C13004
xref: SCTID:362013006
xref: TAO:0001320
xref: UMLS:C0014124 {source="ncithesaurus:Endocardium"}
xref: VHOG:0000084
xref: Wikipedia:Endocardium
xref: XAO:0000066
xref: ZFA:0001320
is_a: UBERON:0002523 ! tunica intima
is_a: UBERON:0005983 ! heart layer
relationship: develops_from UBERON:0007280 ! presumptive endocardium
relationship: has_part UBERON:0005316 ! endocardial endothelium
relationship: immediate_transformation_of UBERON:0007280 {source="Bgee:AN"} ! presumptive endocardium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png" xsd:anyURI
property_value: UBPROP:0000001 "Layer that lines the lumen of the heart.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001320", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Part of the heart comprised of thin serous membrane, composed of endothelial tissue, that lines the interior of the heart.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010408", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "Tunica intima which has as its parts the endothelium of endocardium and the fibroelastic connective tissue that surrounds the cavity of a cardiac chamber." xsd:string {source="FMA:7280"}

[Term]
id: UBERON:0002166
name: endocardium of atrium
namespace: uberon
def: "Endocardium that is part of the atrium." [ZFIN:curator]
subset: pheno_slim
subset: vertebrate_core
synonym: "atrial endocardium" EXACT []
synonym: "atrium endocardial tissue" RELATED [VHOG:0000606]
synonym: "atrium endocardium" EXACT []
synonym: "atrium of heart endocardium" EXACT [OBOL:automatic]
synonym: "Cardiac atria endocardium" EXACT [OBOL:automatic]
synonym: "cardiac atrium endocardium" EXACT [OBOL:automatic]
synonym: "endocardium of atrium of heart" EXACT [OBOL:automatic]
synonym: "endocardium of Cardiac atria" EXACT [OBOL:automatic]
synonym: "endocardium of cardiac atrium" EXACT [OBOL:automatic]
synonym: "endocardium of heart atrium" EXACT [OBOL:automatic]
synonym: "heart atrium endocardium" EXACT [OBOL:automatic]
xref: EMAPA:32745
xref: FMA:7284
xref: MA:0000077
xref: SCTID:192001005
xref: TAO:0002169
xref: VHOG:0000606
xref: ZFA:0001614
is_a: UBERON:0002165 ! endocardium
intersection_of: UBERON:0002165 ! endocardium
intersection_of: part_of UBERON:0002081 ! cardiac atrium
relationship: contributes_to_morphology_of UBERON:0002081 ! cardiac atrium
relationship: part_of UBERON:0002081 ! cardiac atrium

[Term]
id: UBERON:0002167
name: right lung
namespace: uberon
def: "Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]." [FMA:FMA, Wikipedia:Right_lung]
subset: pheno_slim
subset: uberon_slim
xref: EHDAA2:0001730
xref: EHDAA:4969
xref: EMAPA:17661
xref: FMA:7309
xref: MA:0000426
xref: NCIT:C33483
xref: SCTID:361967000
xref: UMLS:C0225706 {source="ncithesaurus:Right_Lung"}
xref: VHOG:0000301
xref: Wikipedia:Right_lung
is_a: UBERON:0002048 ! lung
intersection_of: UBERON:0002048 ! lung
intersection_of: in_right_side_of UBERON:0000170 ! pair of lungs
relationship: in_right_side_of UBERON:0000170 ! pair of lungs
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/32/Gray972.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb" xsd:anyURI
property_value: UBPROP:0000003 "Lungs had already developed as paired ventral pockets from the intestine in the ancestor of Osteognathostomata.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000301", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.210", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0002168
name: left lung
namespace: uberon
def: "Lung which consists of the left upper lobe and left lower lobe.[FMA]." [FMA:FMA, Wikipedia:Left_lung]
subset: pheno_slim
subset: uberon_slim
xref: EHDAA2:0000943
xref: EHDAA:4947
xref: EMAPA:17653
xref: FMA:7310
xref: MA:0000425
xref: NCIT:C32967
xref: SCTID:361982005
xref: UMLS:C0225730 {source="ncithesaurus:Left_Lung"}
xref: VHOG:0000618
xref: Wikipedia:Left_lung
is_a: UBERON:0002048 ! lung
intersection_of: UBERON:0002048 ! lung
intersection_of: in_left_side_of UBERON:0000170 ! pair of lungs
relationship: in_left_side_of UBERON:0000170 ! pair of lungs
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/dd/Gray973.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb" xsd:anyURI
property_value: UBPROP:0000003 "Lungs had already developed as paired ventral pockets from the intestine in the ancestor of Osteognathostomata.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000618", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.210", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0002190
name: subcutaneous adipose tissue
namespace: uberon
alt_id: UBERON:0008875
def: "A portion of adipose tissue that is part of the hypodermis, beneath the dermis." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
synonym: "fatty layer of subcutaneous tissue" EXACT [FMA:74315]
synonym: "fatty layer of superficial fascia" RELATED [FMA:74315]
synonym: "hypodermis fat layer" EXACT [MP:0011156]
synonym: "panniculus adiposus" BROAD [MP:0011156]
synonym: "panniculus adiposus (tela subcutanea)" EXACT OMO:0003011 [FMA:74315, FMA:TA]
synonym: "panniculus adiposus telae subcutaneae" EXACT OMO:0003011 [FMA:74315, FMA:TA]
synonym: "subcutaneous fat" RELATED [BTO:0004042]
synonym: "subcutaneous fat layer" EXACT [MP:0011156]
xref: BTO:0004042
xref: EMAPA:35829
xref: FMA:74315
xref: MA:0000473
xref: MESH:D015434 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
is_a: UBERON:0001013 ! adipose tissue
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0001013 ! adipose tissue
intersection_of: part_of UBERON:0002072 ! hypodermis
relationship: contributes_to_morphology_of UBERON:0002072 ! hypodermis
relationship: part_of UBERON:0002072 ! hypodermis
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "the superficial portion of the subcutaneous tissue which is specialized for fat storage[MP:0011156]" xsd:string {source="MP:0011156"}

[Term]
id: UBERON:0002193
name: hemolymphoid system
namespace: uberon
def: "Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs." [http://orcid.org/0000-0002-6601-2165]
synonym: "haemolymphoid system" RELATED []
synonym: "hematolymphoid system" EXACT []
synonym: "lymphomyeloid complex" EXACT []
xref: CALOHA:TS-2018
xref: EHDAA2:0004615
xref: EMAPA:18765
xref: FMA:74562
xref: MA:0000013
is_a: UBERON:0000467 {source="MA"} ! anatomical system
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria

[Term]
id: UBERON:0002199
name: integument
namespace: uberon
def: "The dermis, epidermis and hypodermis." [Wikipedia:Integument]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "dermal system" RELATED [BTO:0000634]
synonym: "dermis plus epidermis plus hypodermis" EXACT []
synonym: "dermoid system" RELATED [BTO:0000634]
synonym: "integumentum commune" EXACT OMO:0003011 [FMA:74657, FMA:TA]
synonym: "skin" RELATED []
synonym: "skin and subcutaneous tissue" EXACT []
synonym: "skin plus hypodermis" EXACT []
synonym: "tegument" RELATED [BTO:0000634]
synonym: "the integument" EXACT [FMA:74657]
synonym: "vertebrate integument" RELATED []
xref: AAO:0000239
xref: BTO:0000634
xref: EMAPA:37504 {source="MA:th"}
xref: FMA:74657
xref: galen:Integument
xref: TAO:0000368
xref: VSAO:0000029
xref: Wikipedia:Integument
xref: ZFA:0000368
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0011216 {source="FMA"} ! organ system subdivision
relationship: bounding_layer_of UBERON:0000468 ! multicellular organism
relationship: has_part UBERON:0002072 ! hypodermis
relationship: has_part UBERON:0002097 ! skin of body
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
relationship: part_of UBERON:0002416 {source="FMA"} ! integumental system
property_value: curator_notes "in FMA intergument = skin+superficial fascia(hypodermis), skin=dermis+epidermis+hair_nail. Note that the definition provided here excludes the more general sense of the term 'integument' used in invertebrates; consider 'integumental system'. Note that the VSAO class appears to include adnexa by its definition." xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anatomical system that protects the body from damage, comprising the skin and its appendages.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000239", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "Surface structure that is the outer protective covering of the body.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000029", ontology="VSAO", source="PSPUB:0000170"}
property_value: UBPROP:0000001 "The outer protective barrier that separates the animal from its aquatic environment. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000368", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000007 "integumental" xsd:string
property_value: UBPROP:0000007 "integumentary" xsd:string

[Term]
id: UBERON:0002200
name: vasculature of head
namespace: uberon
def: "Vasculature that is part of a head [Automatically generated definition]." [OBOL:automatic]
subset: efo_slim
subset: vertebrate_core
synonym: "adult head vascular network" EXACT [OBOL:automatic]
synonym: "adult head vasculature" EXACT [OBOL:automatic]
synonym: "cranial vasculature" EXACT []
synonym: "head vascular network" EXACT [OBOL:automatic]
synonym: "head vasculature" RELATED []
synonym: "vascular network of adult head" EXACT [OBOL:automatic]
synonym: "vascular network of head" EXACT [OBOL:automatic]
synonym: "vasculature of adult head" EXACT [OBOL:automatic]
xref: EFO:0003656
xref: FMA:74710
xref: TAO:0001267
xref: XAO:0004152
xref: ZFA:0001267
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0000033 ! head

[Term]
id: UBERON:0002201
name: vasculature of trunk
namespace: uberon
def: "A vasculature that is part of a trunk [Automatically generated definition]." [OBOL:automatic]
subset: vertebrate_core
synonym: "torso vascular network" EXACT [OBOL:automatic]
synonym: "torso vasculature" EXACT [OBOL:automatic]
synonym: "trunk vascular network" EXACT [OBOL:automatic]
synonym: "trunk vasculature" EXACT []
synonym: "vascular network of torso" EXACT [OBOL:automatic]
synonym: "vascular network of trunk" EXACT [OBOL:automatic]
synonym: "vasculature of torso" EXACT [OBOL:automatic]
xref: FMA:74712
xref: TAO:0005024
xref: ZFA:0005024
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk

[Term]
id: UBERON:0002203
name: vasculature of eye
namespace: uberon
def: "Vasculature that is part of the eye region." [https://sourceforge.net/tracker/?func=detail&aid=3489658&group_id=76834&atid=994726, OBOL:automatic]
subset: human_reference_atlas
subset: pheno_slim
subset: vertebrate_core
synonym: "eye vascular network" EXACT [OBOL:automatic]
synonym: "eye vasculature" RELATED []
synonym: "ocular blood vessel" EXACT [ZFA:0007057]
synonym: "ocular vasculature" EXACT []
synonym: "optic vasculature" RELATED []
synonym: "vascular network of eye" EXACT [OBOL:automatic]
xref: FMA:74743
xref: SCTID:123846009
xref: TAO:0007057
xref: ZFA:0007057
is_a: UBERON:0002200 ! vasculature of head
is_a: UBERON:0006876 ! vasculature of organ
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0000019 ! camera-type eye
relationship: develops_from UBERON:0003314 {source="ISBN:0781772214"} ! eye mesenchyme
relationship: part_of UBERON:0000019 ! camera-type eye
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "not part of the eye in ZFA. Note this changed to a blood vessel in ZFA" xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0002204
name: musculoskeletal system
namespace: uberon
def: "Anatomical system that consists of the muscular and skeletal systems." [https://github.com/obophenotype/uberon/issues/77, VSAO:0000031, VSAO:curator]
subset: uberon_slim
synonym: "musculo-skeletal system" EXACT []
xref: AAO:0010546
xref: CALOHA:TS-1311
xref: EMAPA:32714
xref: EV:0100139
xref: FMA:7482
xref: GAID:98
xref: MA:0002418
xref: MESH:D009141
xref: NCIT:C12754
xref: SCTID:278858007
xref: UMLS:C0026860 {source="ncithesaurus:Musculoskeletal_System"}
xref: VHOG:0001275
xref: VSAO:0000031
xref: Wikipedia:Musculoskeletal_system
xref: XAO:0000168
is_a: UBERON:0000467 ! anatomical system
disjoint_from: UBERON:0002294 ! biliary system
disjoint_from: UBERON:0002330 ! exocrine system
disjoint_from: UBERON:0002390 ! hematopoietic system
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: capable_of_part_of GO:0040011 ! locomotion
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: has_developmental_contribution_from UBERON:0000926 {notes="check ctenophore"} ! mesoderm
relationship: has_part UBERON:0000383 ! musculature of body
relationship: has_part UBERON:0001434 ! skeletal system
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: UBPROP:0000001 "Anatomical system that provides locomotion and physical support to the organism.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010546", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "There are more than 50,000 extant vertebrate species, representing over 500 million years of evolution. During that time, the vertebrate musculoskeletal systems have adapted to aquatic, terrestrial, fossorial, and arboreal lifestyles, while simultaneously retaining functionally integrated axial and appendicular skeletal systems.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001275", ontology="VHOG", source="DOI:10.1002/jez.b.21246 Shearman RM, Burke AC, The lateral somitic frontier in ontogeny and phylogeny. Journal of Experimental Zoology (2009)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "musculoskeletal" xsd:string

[Term]
id: UBERON:0002213
name: cartilaginous joint
namespace: uberon
def: "Nonsynovial joint in which the articulating bones or cartilages are connected by cartilage. Examples: Spheno-occipital synchondrosis, first sternocostal joint, pubic symphysis.[FMA]." [FMA:FMA, Wikipedia:Cartilaginous_joint]
subset: uberon_slim
subset: vertebrate_core
synonym: "articulatio cartilaginea" EXACT []
synonym: "junctura cartilaginea" RELATED OMO:0003011 [Wikipedia:Cartilaginous_joint]
xref: EMAPA:36581
xref: FMA:7496
xref: MA:0000320
xref: SCTID:58442004
xref: TAO:0005155
xref: Wikipedia:Cartilaginous_joint
xref: ZFA:0005155
is_a: UBERON:0011134 {source="FMA"} ! nonsynovial joint
intersection_of: UBERON:0011134 ! nonsynovial joint
intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue
relationship: composed_primarily_of UBERON:0002418 ! cartilage tissue

[Term]
id: UBERON:0002217
name: synovial joint
namespace: uberon
def: "Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA]." [FMA:7501, Wikipedia:Synovial_joint]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "articulatio synoviale" EXACT []
synonym: "diarthrodial joints" RELATED OMO:0003004 [ZFA:0005153]
synonym: "diarthroses" EXACT OMO:0003004 [ZFA:0005153]
synonym: "diarthrosis" EXACT []
synonym: "diarthrosis joint" EXACT []
xref: AEO:0000183
xref: CALOHA:TS-2138
xref: EHDAA2:0003183
xref: FMA:7501
xref: galen:SynovialJoint
xref: MA:0000322
xref: NCIT:C32461
xref: SCTID:113234001
xref: TAO:0005153
xref: Wikipedia:Synovial_joint
xref: ZFA:0005153
is_a: UBERON:0000982 ! skeletal joint
intersection_of: UBERON:0000982 ! skeletal joint
intersection_of: surrounded_by UBERON:0001484 ! articular capsule
disjoint_from: UBERON:0011134 ! nonsynovial joint
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: surrounded_by UBERON:0001484 ! articular capsule
property_value: UBPROP:0000001 "Is a joint that is located at the point of contact of articulating bones allowing movement. The joint has a capsule containing synovial fluid surrounding the articulating bone surfaces.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005153", ontology="TAO", source="ZFIN:Curator"}

[Term]
id: UBERON:0002224
name: thoracic cavity
namespace: uberon
def: "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." [UBERON:cjm, Wikipedia:Thoracic_cavity]
subset: pheno_slim
subset: uberon_slim
synonym: "cavitas thoracis" EXACT OMO:0003011 [Wikipedia:Thoracic_cavity]
synonym: "cavity of chest" EXACT []
synonym: "cavity of thorax" EXACT []
synonym: "chest cavity" EXACT []
synonym: "pectoral cavity" EXACT []
synonym: "space of thoracic compartment" EXACT [FMA:7565]
synonym: "thoracic lumen" EXACT []
xref: EMAPA:36497
xref: FMA:7565
xref: GAID:93
xref: MA:0000032
xref: MESH:D035423
xref: NCIT:C12905
xref: SCTID:243949006
xref: UMLS:C0230139 {source="ncithesaurus:Thoracic_Cavity"}
xref: Wikipedia:Thoracic_cavity
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000915 ! thoracic segment of trunk
intersection_of: part_of UBERON:0002323 ! coelemic cavity lumen
relationship: luminal_space_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0002323 ! coelemic cavity lumen
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/ce/Gray846.png" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI
property_value: UBPROP:0000008 "In many species, the diaphragm separates thoracic and abdominal cavities" xsd:string

[Term]
id: UBERON:0002240
name: spinal cord
namespace: uberon
def: "Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO)." [BIRNLEX:1709]
subset: cumbo
subset: efo_slim
subset: human_reference_atlas
subset: major_organ
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cerebro-cerebellar fissure" RELATED [NeuroNames:22]
synonym: "cerebrocerebellar fissure" RELATED [NeuroNames:22]
synonym: "fissura cerebro-cerebellaris" RELATED OMO:0003011 [NeuroNames:22]
synonym: "fissura cerebrocerebellaris" RELATED OMO:0003011 [NeuroNames:22]
synonym: "medulla spinalis" RELATED OMO:0003011 [BTO:0001279, Wikipedia:Spinal_cord]
synonym: "SpC" RELATED OMO:0003000 []
synonym: "spinal cord structure" RELATED [ZFA:0000075]
synonym: "spinal medulla" RELATED [BTO:0001279]
xref: AAO:0010151
xref: BAMS:SP
xref: BAMS:Spinal
xref: BIRNLEX:1709
xref: BM:SpC
xref: BTO:0001279
xref: CALOHA:TS-0953
xref: DHBA:12890
xref: DMBA:17651
xref: EFO:0000110
xref: EHDAA2:0001255
xref: EHDAA:2863
xref: EMAPA:17577
xref: EV:0100316
xref: FMA:7647
xref: GAID:695
xref: MA:0000216
xref: MAT:0000183
xref: MESH:D013116
xref: MIAA:0000183
xref: NCIT:C12464
xref: neuronames:22 {source="BIRNLEX:1709"}
xref: SCTID:180959008
xref: TAO:0000075
xref: UMLS:C0037925 {source="ncithesaurus:Spinal_Cord", source="BIRNLEX:1709"}
xref: VHOG:0000601
xref: Wikipedia:Spinal_cord
xref: XAO:0000020
xref: ZFA:0000075
is_a: UBERON:0000489 ! cavitated compound organ
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005174 ! dorsal region element
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
relationship: develops_from UBERON:0003076 ! posterior neural tube
relationship: develops_from UBERON:0006241 ! future spinal cord
relationship: has_developmental_contribution_from UBERON:0003853 {evidence="definitional"} ! spinal cord neural crest
relationship: has_part CL:0005000 {source="ZFA"} ! spinal cord interneuron
relationship: immediate_transformation_of UBERON:0006241 {evidence="definitional"} ! future spinal cord
relationship: part_of UBERON:0001017 ! central nervous system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/58/Spinal_cord_direv.svg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Spinal_Cord.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spinal_Cord.glb" xsd:anyURI
property_value: editor_note "TODO - add superclass to unify with VNC?" xsd:string
property_value: RO:0002171 UBERON:0000955 {exceptions="ZFA", source="https://github.com/obophenotype/uberon/issues/378", status="pending"}
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Part of the central nervous system which descends from the hindbrain within the vertebral column.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010151", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000601", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002241
name: chondrocranium
namespace: uberon
def: "Endoskeletal elements that encase the brain, nose, inner ear[cjm]. that part of the neurocranium formed by endochondral ossification and comprising the bones of the base of the skull[TFD]." [http://medical-dictionary.thefreedictionary.com/chondrocranium, Wikipedia:Chondrocranium]
subset: vertebrate_core
synonym: "calvarium" RELATED [MA:0000317]
synonym: "neurocranium" RELATED INCONSISTENT [MA:0000317]
xref: AAO:0010169
xref: EHDAA2:0000243
xref: EMAPA:17681
xref: TAO:0001424
xref: VHOG:0000288
xref: Wikipedia:Chondrocranium
xref: ZFA:0001424
is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system
relationship: overlaps UBERON:0001703 ! neurocranium
property_value: editor_note "we follow the standard evolutionary classification and treat this as endoskeletal. This means what MA calls 'chondrocranium' must in fact be neurocranium, as it includes parts of the dermatocranium (e.g. frontal, parietal)" xsd:string
property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium and composed of cartilage and cartilage replacement bones.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010169", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium and composed of cartilage and cartilage replacement bones.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001424", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000007 "chondrocranial" xsd:string
property_value: UBPROP:0000008 "covers the brain dorsally in chondrichthyans" xsd:string

[Term]
id: UBERON:0002257
name: ventral horn of spinal cord
namespace: uberon
def: "The ventral grey column of the spinal cord[MP]. The neurons of the ventral region of the mature spinal cord participate in motor output[GO]." [GO:0021517, https://sourceforge.net/tracker/?group_id=36855&atid=440764, MP:0005112, Wikipedia:Anterior_horn_of_spinal_cord]
subset: pheno_slim
subset: vertebrate_core
synonym: "anterior column" RELATED [Wikipedia:Anterior_horn_of_spinal_cord]
synonym: "anterior column of the spinal cord" RELATED [Wikipedia:Anterior_horn_of_spinal_cord]
synonym: "anterior gray column of spinal cord" EXACT [FMA:256541]
synonym: "anterior gray horn of spinal cord" EXACT [FMA:256541]
synonym: "anterior grey column of spinal cord" EXACT []
synonym: "anterior horn" EXACT [BIRNLEX:2668]
synonym: "anterior horn (spinal cord)" RELATED [Wikipedia:Anterior_horn_of_spinal_cord]
synonym: "columna grisea anterior medullae spinalis" EXACT OMO:0003011 [FMA:256541, FMA:TA]
synonym: "cornu anterius medullae spinalis" RELATED OMO:0003011 [Wikipedia:Anterior_horn_of_spinal_cord]
synonym: "spinal cord anterior horn" EXACT [BIRNLEX:2668]
synonym: "spinal cord ventral horn" EXACT []
synonym: "ventral gray column of spinal cord" EXACT [FMA:256541]
synonym: "ventral gray matter of spinal cord" EXACT [FMA:256541]
synonym: "ventral grey column of spinal cord" EXACT []
synonym: "ventral grey horn" EXACT [BIRNLEX:2668]
synonym: "ventral horn of the spinal cord" RELATED [BAMS:VH]
synonym: "ventral horn spinal cord" EXACT [ZFA:0000702]
synonym: "ventral horns spinal cord" RELATED OMO:0003004 [VHOG:0001288]
synonym: "ventral region of spinal cord" EXACT []
synonym: "ventral spinal cord" EXACT []
xref: BAMS:VH
xref: BIRNLEX:2668
xref: BTO:0005151
xref: EMAPA:18575
xref: EMAPA:35794
xref: FMA:256541
xref: MA:0001134
xref: NCIT:C33859
xref: neuronames:1751
xref: SCTID:279443000
xref: TAO:0000702
xref: UMLS:C0228569 {source="BIRNLEX:2668"}
xref: UMLS:C0228590 {source="ncithesaurus:Ventral_Horn_of_the_Spinal_Cord"}
xref: VHOG:0001288
xref: Wikipedia:Anterior_horn_of_spinal_cord
xref: ZFA:0000702
is_a: UBERON:0015212 ! lateral structure
is_a: UBERON:0016550 ! spinal cord column
relationship: contributes_to_morphology_of UBERON:0002315 ! gray matter of spinal cord
relationship: has_part CL:0000100 ! motor neuron
relationship: in_lateral_side_of UBERON:0002315 {source="FMA-abduced-lr"} ! gray matter of spinal cord
relationship: part_of UBERON:0002315 ! gray matter of spinal cord
property_value: UBPROP:0000001 "The anterior horn of the spinal cord (or anterior cornu, or anterior column, or ventral horn) is the ventral (front) grey matter section of the spinal cord. The anterior horn contains motor neurons that affect the axial muscles while the posterior horn receives information regarding touch and sensation. The anterior horn is where the cell bodies of alpha motorneurons are located[Wikipedia:Anterior_horn_of_spinal_cord]." xsd:string {source="Wikipedia:Anterior_horn_of_spinal_cord"}

[Term]
id: UBERON:0002275
name: reticular formation
namespace: uberon
def: "A composite substructure of the brainstem that consists of the midbrain reticular formation, the pontine reticular formation and the medullary reticular formation ( Carpenter-1983 )." [NeuroNames:1223]
subset: uberon_slim
synonym: "brain stem reticular formation" EXACT [NeuroNames:1223]
synonym: "brainstem reticular formation" EXACT [MA:0003185, NeuroNames:1223]
synonym: "reticular formation (classical)" EXACT [NeuroNames:1223]
synonym: "reticular formation of the brainstem" EXACT [NeuroNames:1223]
xref: BAMS:RET
xref: EMAPA:35188
xref: FMA:77719
xref: MA:0003185
xref: MESH:D012154
xref: neuronames:1223
xref: NLX:143558
xref: SCTID:361552007
xref: Wikipedia:Reticular_formation
is_a: UBERON:0002616 ! regional part of brain
relationship: part_of UBERON:0002298 ! brainstem
property_value: curator_notes "this class denotes the generic structure, and not a specific one such as medullary or pontine reticular formation." xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/9b/Gray701.png" xsd:anyURI
property_value: UBPROP:0000008 "It is essential for governing some of the basic functions of higher organisms, and is one of the phylogenetically oldest portions of the brain." xsd:string
property_value: UBPROP:0000012 "FMA has a spinal cord reticular formation but we follow NNs (classical) to restrict this to brainstem structures. This means we also include the MA class for brainstem reticular formation here. FMA has subtypes of reticular formation but we treat this as a composite structure" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0002294
name: biliary system
namespace: uberon
def: "Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree)." [Wikipedia:Biliary_system]
subset: pheno_slim
subset: uberon_slim
synonym: "biliary apparatus" EXACT [FMA:79646]
synonym: "biliary tract" RELATED [FMA:79646, MA:0001273]
xref: FMA:79646
xref: GAID:279
xref: MA:0001273
xref: MESH:D001659
xref: NCIT:C12678
xref: SCTID:361354009
xref: Wikipedia:Biliary_system
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0011216 ! organ system subdivision
intersection_of: UBERON:0011216 ! organ system subdivision
intersection_of: capable_of GO:0006699 ! bile acid biosynthetic process
intersection_of: capable_of GO:0015721 ! bile acid and bile salt transport
intersection_of: has_part UBERON:0001173 ! biliary tree
disjoint_from: UBERON:0002330 ! exocrine system
disjoint_from: UBERON:0002390 ! hematopoietic system
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: capable_of GO:0006699 ! bile acid biosynthetic process
relationship: capable_of GO:0015721 ! bile acid and bile salt transport
relationship: has_part UBERON:0001173 ! biliary tree
relationship: part_of UBERON:0002423 ! hepatobiliary system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI
property_value: RO:0002171 UBERON:0016478

[Term]
id: UBERON:0002296
name: dorsal mesentery
namespace: uberon
def: "The mesentery that originates from the dorsal side of the peritoneal cavity[ZFA]." [Wikipedia:Dorsal_mesentery, Wikipedia:Mesentery#Development, ZFIN:curator]
subset: uberon_slim
subset: vertebrate_core
synonym: "dorsal mesogastrium" RELATED [Wikipedia:Dorsal_mesentery]
synonym: "mesenterium dorsale commune" RELATED OMO:0003011 [Wikipedia:Dorsal_mesentery]
xref: EHDAA2:0004560
xref: EHDAA:3019
xref: EHDAA:3033
xref: EHDAA:3921
xref: EHDAA:3934
xref: EHDAA:3957
xref: EHDAA:3971
xref: FMA:79795
xref: SCTID:308823000
xref: TAO:0005130
xref: Wikipedia:Mesentery#Development
xref: ZFA:0005130
is_a: UBERON:0006598 ! presumptive structure
relationship: has_potential_to_develop_into UBERON:0002095 ! mesentery
relationship: part_of UBERON:0009664 {source="EHDAA2"} ! gut mesentery
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/85/Gray985.png" xsd:anyURI
property_value: UBPROP:0000001 "The mesentery that originates from the dorsal side of the peritoneal cavity.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005130", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0002298
name: brainstem
namespace: uberon
def: "Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]." [ISBN:0471888893, MP:0005277, Wikipedia:Brainstem, ZFA:0001707]
comment: 'brainstem' is a loose term that sometimes refers to the ventral parts o the brain except for any part of the telencephalon - sometimes it includes the diencephalon or subpallial telencephalon structures (ISBN:0471888893). Here we use it in a more restriced sense, to include only the medulla oblongata, pons (when present) and the midbrain tegmentum (following the ZFA definitions).
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "accessory medullary lamina of pallidum" RELATED [NeuroNames:236]
synonym: "brain stem" EXACT [ABA:BS]
synonym: "lamella pallidi incompleta" RELATED OMO:0003011 [NeuroNames:236]
synonym: "lamina medullaris accessoria" RELATED OMO:0003011 [NeuroNames:236]
synonym: "lamina medullaris incompleta pallidi" RELATED OMO:0003011 [NeuroNames:236]
synonym: "lamina pallidi incompleta" RELATED OMO:0003011 [NeuroNames:236]
synonym: "truncus encephali" EXACT OMO:0003011 [Wikipedia:Brainstem]
synonym: "truncus encephalicus" RELATED OMO:0003011 [BTO:0000146]
xref: BAMS:BS
xref: BIRNLEX:1565
xref: BTO:0000146
xref: CALOHA:TS-0093
xref: EFO:0001962
xref: EMAPA:32678
xref: EV:0100241
xref: FMA:79876
xref: MA:0000169
xref: MBA:343
xref: MESH:D001933
xref: NCIT:C12441
xref: neuronames:236 {source="BIRNLEX:1565"}
xref: SCTID:180925009
xref: TAO:0002156
xref: UMLS:C0006121 {source="BIRNLEX:1565", source="ncithesaurus:Brain_Stem"}
xref: VHOG:0001457
xref: Wikipedia:Brainstem
xref: ZFA:0001707
is_a: UBERON:0002616 ! regional part of brain
relationship: continuous_with UBERON:0002240 ! spinal cord
relationship: contributes_to_morphology_of UBERON:0000955 ! brain
relationship: has_part UBERON:0001896 ! medulla oblongata
relationship: has_part UBERON:0001943 ! midbrain tegmentum
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray719.png" xsd:anyURI
property_value: RO:0002171 UBERON:0001890 {notes="we apply a strict definition"}
property_value: RO:0002171 UBERON:0002037 {exceptions="ZFA", source="ABA", source="https://github.com/obophenotype/uberon/issues/378", status="pending"}
property_value: RO:0002171 UBERON:0002314 {notes="we apply a strict definition"}
property_value: UBPROP:0000001 "Multi-tissue structure that has as its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002156", ontology="TAO", source="ISBN:3764351209"}
property_value: UBPROP:0000001 "Multi-tissue structure that has as its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,adopted][ZFA:0001707]." xsd:string {source="ZFA:0001707"}
property_value: UBPROP:0000001 "the stalk-like part of the brain that comprises the midbrain (aka mesencephalon), the pons (aka pons Varolii), and the medulla oblongata, and connects the cerebral hemispheres with the cervical spinal cord[MP]" xsd:string {source="MP:0005277"}

[Term]
id: UBERON:0002302
name: myocardium of atrium
namespace: uberon
def: "The atrial part of middle layer of the heart, comprised of involuntary muscle." [ISBN:0-683-40008-8, MP:0010493]
subset: efo_slim
subset: pheno_slim
subset: vertebrate_core
synonym: "atrial myocardium" EXACT [ZFA:0001374]
synonym: "atrium cardiac muscle" RELATED [VHOG:0000602]
synonym: "atrium myocardium" EXACT []
xref: EFO:0003087
xref: EMAPA:32746
xref: FMA:83509
xref: MA:0000081
xref: SCTID:191910002
xref: TAO:0001374
xref: VHOG:0000602
xref: ZFA:0001374
is_a: UBERON:0002349 ! myocardium
intersection_of: UBERON:0002349 ! myocardium
intersection_of: part_of UBERON:0002081 ! cardiac atrium
relationship: contributes_to_morphology_of UBERON:0002081 ! cardiac atrium
relationship: part_of UBERON:0002081 ! cardiac atrium
property_value: UBPROP:0000003 "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000602", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002308
name: nucleus of brain
namespace: uberon
def: "A neural nucleus that is part of the brain." [http://orcid.org/0000-0002-6601-2165]
synonym: "brain nuclei" RELATED OMO:0003004 [ZFA:0005575]
synonym: "brain nucleus" EXACT []
xref: EMAPA:35185
xref: FMA:83840
xref: MA:0000811
xref: NCIT:C49346
xref: SCTID:426465002
xref: UMLS:C1706993 {source="ncithesaurus:Brain_Nucleus"}
xref: ZFA:0005575
is_a: UBERON:0000125 ! neural nucleus
intersection_of: UBERON:0000125 ! neural nucleus
intersection_of: part_of UBERON:0000955 ! brain
relationship: part_of UBERON:0003528 ! brain gray matter

[Term]
id: UBERON:0002315
name: gray matter of spinal cord
namespace: uberon
def: "The ridge-shaped grey matter of the spinal cord that extends longitudunally through the center of each half of the spinal cord, and are largely or entirely composed of nerve cell bodies and their dendrites and some supportive tissue." [MP:0008503]
subset: pheno_slim
synonym: "gray matter of spinal cord" EXACT [OBOL:automatic]
synonym: "gray substance of spinal cord" EXACT [FMA:256580]
synonym: "grey matter of spinal cord" EXACT []
synonym: "grey substance of spinal cord" EXACT []
synonym: "spinal cord gray matter" EXACT [OBOL:automatic]
synonym: "spinal cord grey matter" EXACT []
synonym: "spinal cord grey substance" EXACT [OBOL:automatic]
synonym: "substantia grisea medullae spinalis" EXACT OMO:0003011 [FMA:256580, FMA:TA]
xref: BAMS:Scgrey
xref: DHBA:146035048
xref: EMAPA:35792
xref: FMA:256580
xref: MA:0000002
xref: NCIT:C32696
xref: neuronames:2619
xref: NLXANAT:100204
xref: SCTID:279441003
xref: UMLS:C0475853 {source="ncithesaurus:Gray_Matter_of_the_Spinal_Cord"}
is_a: UBERON:0002020 ! gray matter
intersection_of: UBERON:0002020 ! gray matter
intersection_of: part_of UBERON:0002240 ! spinal cord
relationship: contributes_to_morphology_of UBERON:0002240 ! spinal cord
relationship: part_of UBERON:0002240 ! spinal cord

[Term]
id: UBERON:0002323
name: coelemic cavity lumen
namespace: uberon
alt_id: UBERON:0000169
def: "The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities." [BTO:0001707]
comment: EDITOR_NOTE check the FMA placement here; ncit placement of body cavity here probably not correct
subset: uberon_slim
subset: vertebrate_core
synonym: "body cavity" BROAD [BTO:0001707]
synonym: "celom" RELATED [BTO:0001707]
synonym: "coelom" RELATED []
synonym: "coelome" RELATED [BTO:0001707]
synonym: "coelomic cavity" EXACT [EHDAA2:0000267]
synonym: "coelomic cavity lumen" EXACT [EHDAA2:0000267]
synonym: "hemocoel" RELATED [FBbt:00005060]
synonym: "main body cavity" EXACT []
synonym: "space of body compartment" EXACT [FMA:85006]
synonym: "ventral body cavity" NARROW [NCBITaxon:7742]
xref: AEO:0000186
xref: BTO:0001707
xref: EHDAA2:0000267
xref: FBbt:00005060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:85006
xref: galen:BodyCavity
xref: NCIT:C25444
xref: RETIRED_EHDAA2:0003186
xref: SCTID:361348008
xref: TAO:0001438
xref: UMLS:C0333343 {source="ncithesaurus:Cavity"}
xref: ZFA:0001438
is_a: UBERON:0002553 ! anatomical cavity
relationship: develops_from UBERON:0003886 ! future coelemic cavity lumen
relationship: luminal_space_of UBERON:0011997 ! coelom
relationship: part_of UBERON:0011997 ! coelom
relationship: transformation_of UBERON:0003886 {evidence="definitional"} ! future coelemic cavity lumen
property_value: UBPROP:0000001 "Anatomical space, part of the trunk that contains the pericardial and pleuroperitoneal cavities[ZFA]." xsd:string {date_retrieved="2012-09-12", external_class="ZFA:0001438", ontology="ZFA", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities[BTO]." xsd:string {date_retrieved="2012-09-12", external_class="BTO:0001707", ontology="BTO", source="BTO"}
property_value: UBPROP:0000008 "In mammals it forms the peritoneal, pleural, and pericardial cavities" xsd:string

[Term]
id: UBERON:0002324
name: muscle of back
namespace: uberon
def: "Any muscle organ that is part of a back [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "back muscle" EXACT []
synonym: "back muscle organ" EXACT [OBOL:automatic]
synonym: "muscle organ of back" EXACT [OBOL:automatic]
xref: EMAPA:35161
xref: FMA:85216
xref: MA:0000496
is_a: UBERON:0001774 ! skeletal muscle of trunk
is_a: UBERON:0005174 ! dorsal region element
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0001137 ! dorsum
relationship: part_of UBERON:0004469 {source="prolog"} ! musculature of back
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002325
name: epithelium of urethra
namespace: uberon
def: "The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.." [GO:0061071]
synonym: "epithelial tissue of urethra" EXACT [OBOL:automatic]
synonym: "urethra epithelial tissue" EXACT [OBOL:automatic]
synonym: "urethra epithelium" EXACT []
synonym: "urethral epithelium" RELATED []
synonym: "urethral plate" RELATED [EMAPA:31518]
synonym: "urethral seam" RELATED [EMAPA:31518]
xref: EMAPA:31518
xref: FMA:85275
xref: MA:0001686
xref: NCIT:C49309
xref: UMLS:C1710584 {source="ncithesaurus:Urethra_Epithelium"}
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0003914 {source="GO"} ! epithelial tube
is_a: UBERON:0005911 ! endo-epithelium
is_a: UBERON:0006555 ! excretory tube
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000057 ! urethra
relationship: part_of UBERON:0000057 ! urethra

[Term]
id: UBERON:0002326
name: lamina propria of urethra
namespace: uberon
def: "A lamina propria that is part of a urethra [Automatically generated definition]." [OBOL:automatic]
synonym: "lamina propria mucosa of urethra" EXACT [OBOL:automatic]
synonym: "lamina propria mucosae of urethra" EXACT [OBOL:automatic]
synonym: "urethra lamina propria" EXACT []
synonym: "urethra lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "urethra lamina propria mucosae" EXACT [OBOL:automatic]
synonym: "urethral lamina propria" RELATED []
xref: EMAPA:37785 {source="MA:th"}
xref: FMA:85276
xref: MA:0001689
is_a: UBERON:0000030 ! lamina propria
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0000057 ! urethra
relationship: part_of UBERON:0000057 ! urethra

[Term]
id: UBERON:0002328
name: notochord
namespace: uberon
def: "A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube." [http://tolweb.org/Chordata/2499, https://github.com/obophenotype/uberon/issues/25, https://github.com/obophenotype/uberon/issues/271, ISBN:0815318960, Wikipedia:Notochord]
comment: The notochord appears early in embryogeny and plays an important role in promoting or organizing the embryonic development of nearby structures. In most adult chordates the notochord disappears or becomes highly modified. In some non-vertebrate chordates and fishes the notochord persists as a laterally flexible but incompressible skeletal rod that prevents telescopic collapse of the body during swimming[TOLWEB]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "embryonic notocord" EXACT []
synonym: "notochorda" RELATED OMO:0003011 [Wikipedia:Notochord]
synonym: "notocord" EXACT [ZFA:0000135]
xref: AAO:0000327
xref: BTO:0001768
xref: CALOHA:TS-0690
xref: EHDAA2:0001277
xref: EHDAA:1241
xref: EHDAA:6021
xref: EMAPA:16191
xref: EV:0100002
xref: FMA:85521
xref: GAID:1311
xref: http://evolution.berkeley.edu/evolibrary/images/history/notochords.jpg
xref: MAT:0000281
xref: MESH:D009672
xref: NCIT:C12463
xref: SCTID:308820002
xref: TAO:0000135
xref: UMLS:C0028439 {source="ncithesaurus:Notochord"}
xref: VHOG:0000199
xref: VSAO:0000032
xref: Wikipedia:Notochord
xref: XAO:0000055
xref: ZFA:0000135
is_a: UBERON:0000062 {source="PMID:15890825"} ! organ
is_a: UBERON:0000481 {source="VSAO"} ! multi-tissue structure
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: develops_from UBERON:0004880 {source="ZFA"} ! chordamesoderm
relationship: develops_from UBERON:0006267 {source="EHDAA2"} ! notochordal plate
relationship: dorsal_to UBERON:0001555 ! digestive tract
relationship: existence_starts_during UBERON:0000068 ! embryo stage
relationship: only_in_taxon NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! Chordata
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000922 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! embryo
relationship: part_of UBERON:0011137 ! axial skeletal system
relationship: produces PR:000014841 ! sonic hedgehog protein
relationship: ventral_to UBERON:0001049 ! neural tube
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul
property_value: UBPROP:0000001 "Avascular multi-tissue structure composed of large vacuolated epithelial cells (chordablasts) and perichordal fibrous tissue.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000032", ontology="VSAO", source="PSPUB:0000170"}
property_value: UBPROP:0000001 "Rod-like principal supportive element of the embryo and larva, present in the midline just ventral to the neural tube, and differentiating during the segmentation period to form large vacuolated epithelial cells and a surrounding a sheath of fibrous and elastic layers. Layering of the sheath may differ in structure, thickness and development among groups; in cypriniforms there are actually three very thin layers to the sheath. A functional, well developed notochord is present throughout life in certain basal fish groups but not in cypriniforms. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000135", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Slender rod of fibrous connective tissue surrounding a core of fluid-filled cells of mesodermal origin; it lies above the gut and directly beneath the spinal cord. The notochord is present during early development and in a few cases it is retained through life; however, usually the notochord is replaced by the vertebral column.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000327", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000002 "relationship type change: differentiates_from mesoderm (AAO:0000304) CHANGED TO: develops_from mesoderm (UBERON:0000926)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000327", ontology="AAO"}
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (3) a stiff, longitudinal rod of turgid cells along the dorsal part of the body that is called a notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000199", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "notochordal" xsd:string
property_value: UBPROP:0000011 "In between vertebra the notochord becomes the nucleus pulposus, under it degenerates, and at anterior end in some species its tissue merges with some of the cranial bones.. Some organisms retain a post-embryonic notochord." xsd:string

[Term]
id: UBERON:0002329
name: somite
namespace: uberon
def: "Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm." [DOI:10.1111/j.1439-0426.2012.01987.x, Wikipedia:Somite]
comment: When the somite becomes segmented from the segmental plate, it is composed of an epithelial sac enclosing mesenchymal somitocoel cells. Thereafter the somite differentiates into two parts, the ventro-medial mesenchymal sclerotome and the dorso-lateral epithelial dermomyotome. This change in the epithelial somite depends on surrounding tissue [PMID:15906248]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "epimere" RELATED [ISBN:0073040584]
synonym: "epimere mesoderm" RELATED []
synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wiki/The-neural-crest]
synonym: "mesodermal cluster" BROAD [GO:0001756]
synonym: "somites" RELATED OMO:0003004 []
synonym: "somitic mesoderm" RELATED []
synonym: "somitus" RELATED OMO:0003011 [Wikipedia:Somite]
xref: AAO:0010569
xref: AEO:0001015
xref: BTO:0001558
xref: EHDAA2:0003436
xref: EHDAA:366
xref: EHDAA:699
xref: EMAPA:31169
xref: FMA:85522
xref: GAID:1306
xref: MAT:0000068
xref: MESH:D019170
xref: MIAA:0000068
xref: NCIT:C34302
xref: TAO:0000155
xref: UMLS:C0376449 {source="ncithesaurus:Somite"}
xref: VHOG:0000191
xref: Wikipedia:Somite
xref: XAO:0000058
xref: ZFA:0000155
is_a: UBERON:0005423 ! developing anatomical structure
is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle
relationship: develops_from UBERON:0003059 {source="ZFA"} ! presomitic mesoderm
relationship: only_in_taxon NCBITaxon:7711 {source="GOTAX:0000352"} ! Chordata
property_value: curator_notes "EDITOR_NOTE currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk" xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI
property_value: RO:0002161 NCBITaxon:7712 {source="PMID:17237766"}
property_value: UBPROP:0000001 "Post-cranial axial segments which form sclerotome and dermomyotome.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010569", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "Undifferentiated mesodermal components of early trunk or tail segments or metameres, derived from paraxial mesoderm; forms myotomes, sclerotomes and perhaps dermatomes. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000155", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000002 "relationship loss: develops_from paraxial mesenchyme (TAO:0000942)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000155", ontology="TAO"}
property_value: UBPROP:0000002 "relationship type change: OBO_REL:part_of trunk (TAO:0001115) CHANGED TO: develops_from trunk (UBERON:0002100)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000155", ontology="TAO"}
property_value: UBPROP:0000002 "relationship type change: part_of paraxial mesoderm (AAO:0010568) CHANGED TO: develops_from paraxial mesoderm (UBERON:0003077)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010569", ontology="AAO"}
property_value: UBPROP:0000003 "(...) cephalocordates and craniates belong to a group known as Somitichordata. Somitichordate synapomorphies include (1) somites (...) (reference 1); The idea that the last common ancestor of bilaterian animals (Urbilateria) was segmented has been raised recently on evidence coming from comparative molecular embryology (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000191", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.40, DOI:10.1093/icb/43.1.137 Balavoine G, Adoutte A, The segmented urbilateria: a testable scenario. Integrative and Comparative Biology (2003)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "somitic" xsd:string

[Term]
id: UBERON:0002330
name: exocrine system
namespace: uberon
def: "Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]." [Wikipedia:Exocrine_gland]
subset: pheno_slim
subset: uberon_slim
synonym: "exocrine glandular system" EXACT [EHDAA2:0002225]
xref: CALOHA:TS-2057
xref: EHDAA2:0002225
xref: EMAPA:35329
xref: FMA:85539
xref: MA:0002411
xref: NCIT:C12957
xref: UMLS:C1516995 {source="ncithesaurus:Exocrine_System"}
xref: Wikipedia:Exocrine_gland
xref: WikipediaCategory:Exocrine_system
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000467 ! anatomical system
disjoint_from: UBERON:0002390 ! hematopoietic system
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: composed_primarily_of UBERON:0002365 ! exocrine gland
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa

[Term]
id: UBERON:0002331
name: umbilical cord
namespace: uberon
def: "The connecting cord from the developing embryo to the placenta." [ISBN:0-683-40008-8, MP:0001725, PMID:9144284, Wikipedia:Umbilical_cord]
comment: See notes for connecting stalk
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "birth cord" RELATED [Wikipedia:Umbilical_cord]
synonym: "chorda umbilicalis" EXACT OMO:0003011 [MP:0012134]
synonym: "connecting stalk" RELATED []
synonym: "funiculus umbilicalis" EXACT OMO:0003011 [MP:0012134]
synonym: "funiculus umbilicalis" RELATED OMO:0003011 [Wikipedia:Umbilical_cord]
synonym: "yolk stalk" RELATED [BTO:0001415]
xref: BTO:0001415
xref: CALOHA:TS-1078
xref: EFO:0001415
xref: EHDAA2:0000312
xref: EHDAA:158
xref: EMAPA:26115
xref: EV:0100127
xref: FMA:85541
xref: GAID:517
xref: MAT:0000280
xref: MESH:D014470
xref: MIAA:0000280
xref: NCIT:C34320
xref: SCTID:280644003
xref: UMLS:C0041633 {source="ncithesaurus:Umbilical_Cord"}
xref: Wikipedia:Umbilical_cord
is_a: UBERON:0000478 ! extraembryonic structure
relationship: connects UBERON:0000922 ! embryo
relationship: connects UBERON:0001987 ! placenta
relationship: develops_from UBERON:0007806 ! connecting stalk
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f3/Umbilicalcord.jpg" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The connecting cord from the developing embryo or fetus to the placenta. During prenatal development, the umbilical cord comes from the same zygote as the fetus and (in humans) normally contains two arteries (the umbilical arteries) and one vein (the umbilical vein), buried within Wharton's jelly. The umbilical vein supplies the fetus with oxygenated, nutrient-rich blood from the placenta.property_value, external_definition the umbilical arteries return the deoxygenated, nutrient-depleted blood[WP]." xsd:string {source="Wikipedia:Umbilical_cord"}
property_value: UBPROP:0000007 "umbilical" xsd:string

[Term]
id: UBERON:0002333
name: pulmonary trunk
namespace: uberon
def: "An arterial trunk which is continuous with the heart and branches into the pulmonary arteries." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "main pulmonary artery" RELATED [Wikipedia:Pulmonary_artery]
synonym: "pulmonary artery (trunk)" EXACT []
synonym: "trunk of pulmonary arterial tree" EXACT []
xref: EHDAA2:0001576
xref: EHDAA:9831
xref: EMAPA:17015
xref: FMA:8612
xref: galen:PulmonaryTrunk
xref: MA:0002033
xref: NCIT:C116918
xref: VHOG:0001134
is_a: UBERON:0001637 {source="MA"} ! artery
relationship: connected_to UBERON:0002080 ! heart right ventricle
relationship: continuous_with UBERON:0000948 ! heart
relationship: continuous_with UBERON:0002080 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! heart right ventricle
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0008886 ! pulmonary vascular system
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "An arterial trunk with origin from the right ventricle of the heart, and dividing into the right and left pulmonary arteries, which enter the corresponding lungs and branch with the bronchi. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001134", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/pulmonary+trunk"}
property_value: UBPROP:0000003 "As in birds, the conus arteriosus split during embryonic development in mammals to produce the pulmonary trunk and single aortic trunk of the adult.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001134", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002337
name: endometrial stroma
namespace: uberon
def: "The layer of connective tissue comprised of the endometrial lining of the uterus which fluctuates in thickness throughout the menstrual cycle." [ncithesaurus:Endometrial_Stroma]
subset: human_reference_atlas
synonym: "endometrium stroma" EXACT []
synonym: "stroma of endometrium" EXACT []
xref: CALOHA:TS-1266
xref: EMAPA:35310
xref: FMA:86487
xref: MA:0002734
xref: NCIT:C32516
xref: SCTID:254115004
xref: UMLS:C0227849 {source="ncithesaurus:Endometrial_Stroma"}
is_a: UBERON:0003891 ! stroma
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0003891 ! stroma
intersection_of: part_of UBERON:0001295 ! endometrium
relationship: part_of UBERON:0001295 ! endometrium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002342
name: neural crest
namespace: uberon
def: "A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]." [MP:0009846]
comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995), slug (Nieto et al., 1994), AP-2 (Zhang et al., 1996; Schorle et al., 1996), and Wnt-1/3a (Ikeya et al., 1997) are expressed in the dorsal most region of the neural tube, and have been shown to be involved in the generation of neural crest cells.
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "crista neuralis" RELATED OMO:0003011 [Wikipedia:Neural_crest]
synonym: "NC" EXACT OMO:0003000 [XAO:0000048]
synonym: "neural crest material" RELATED [VHOG:0000057]
xref: AAO:0010578
xref: BTO:0001764
xref: CALOHA:TS-0676
xref: EHDAA2:0004419
xref: EMAPA:32737
xref: FMA:86666
xref: GAID:1310
xref: MAT:0000066
xref: MESH:D009432
xref: MIAA:0000066
xref: NCIT:C34222
xref: neuronames:1366
xref: SCTID:361462002
xref: TAO:0000045
xref: UMLS:C0027789 {source="ncithesaurus:Neural_Crest"}
xref: VHOG:0000057
xref: Wikipedia:Neural_crest
xref: XAO:0000048
xref: ZFA:0000045
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
is_a: UBERON:0010316 ! germ layer / neural crest
relationship: composed_primarily_of CL:0000333 {notes="pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! migratory neural crest cell
relationship: develops_from UBERON:0003075 {source="BTO"} ! neural plate
relationship: develops_from UBERON:0005062 {source="PMID:11523831"} ! neural fold
relationship: existence_starts_during UBERON:0000110 {source="PMID:11523831"} ! neurula stage
relationship: only_in_taxon NCBITaxon:89593 {notes="Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells", source="ISBN:0073040584"} ! Craniata <chordates>
relationship: part_of UBERON:0002346 {source="XAO", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! neurectoderm
property_value: curator_notes "EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams)." xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png" xsd:anyURI
property_value: RO:0002174 NCBITaxon:117565 {source="ISBN:0073040584", source="PMID:17377535"}
property_value: UBPROP:0000001 "A cell population arising from the dorsolateral aspect of the central nervous system primordium during the segmentation period, and later migrating along stereotyped pathways to give rise to a diverse and well-defined set of cell types including pigment cells, peripheral neurons and glia, and head cartilage. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000045", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Migratory cell population which delaminates from neural tube, borders surface ectoderm and neural ectoderm, and gives rise to many different tissue types.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010578", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "A well developed neural crest population is present in lampreys (Horigome et al. 1999 ; Tomsa & Langeland, 1999) and gnathostomes. chordate fossils from the early Cambrian (Yunnanozoan and Haikouella) with apparent neural-crest derived structures (pharyngeal denticles and pharyngeal skeletons resembling the striped mucocartilage of the branchial bars in lamprey ammocoete larvae), suggests that neural crest arose very early in vertebrate evolution (Chen et al. 1999; Holland & Chen, 2001). The invertebrate chordates apparently lack defini- tive neural crest. One marker of migrating neural crest in some vertebrates, the antibody HNK1, does not recognize any cells in amphioxus embryos (Holland, unpublished). Even so, in both amphioxus and tunicates, cells at the edges of the neural plate and adjacent nonneural ectoderm share some properties of neural crest[PMID:11523831]" xsd:string {source="PMID:11523831"}
property_value: UBPROP:0000003 "We conclude that the neural crest is a vertebrate novelty, but that neural crest cells and their derivatives evolved and diversified in a step-wise fashion - first by elaboration of neural plate border cells, then by the innovation or co-option of new or ancient metazoan cell fates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000057", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2012.01495.x Hall BK, Gillis JA, Incremental evolution of the neural crest, neural crest cells and neural crest-derived skeletal tissues. J Anat (2012)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002343
name: abdomen musculature
namespace: uberon
def: "Set of all muscles in abdomen." [OBOL:automatic]
subset: pheno_slim
subset: vertebrate_core
synonym: "abdominal musculature" EXACT []
synonym: "muscle group of abdomen" EXACT [FMA:71294]
synonym: "muscles of abdomen" EXACT [FMA:71294]
synonym: "musculature of abdomen" EXACT []
synonym: "musculature of abdominal wall" EXACT [FMA:86917]
synonym: "set of muscles of abdomen" EXACT [FMA:71294]
xref: FMA:71294
xref: FMA:86917
xref: TAO:0001327
xref: ZFA:0001327
is_a: UBERON:0004479 ! musculature of trunk
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0000916 ! abdomen
property_value: curator_notes "distinction between abdomen muscle and abdomen musculature" xsd:string

[Term]
id: UBERON:0002345
name: descending thoracic aorta
namespace: uberon
def: "The part of the aorta that extends from the arch of the aorta to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest." [MP:0009868]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
xref: EFO:0002527
xref: EMAPA:18605
xref: FMA:87217
xref: MA:0002572
xref: SCTID:181301002
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0013522 ! subdivision of tube
relationship: contributes_to_morphology_of UBERON:0001514 ! descending aorta
relationship: contributes_to_morphology_of UBERON:0001515 ! thoracic aorta
relationship: part_of UBERON:0001514 ! descending aorta
relationship: part_of UBERON:0001515 ! thoracic aorta
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002346
name: neurectoderm
namespace: uberon
def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm]
subset: uberon_slim
subset: vertebrate_core
synonym: "epithelium tubi neuralis; neuroectoderma" RELATED OMO:0003011 [Wikipedia:Neuroectoderm]
synonym: "neuaral ectoderm" RELATED []
synonym: "neural ectoderm" EXACT []
synonym: "neuroectoderm" EXACT []
synonym: "presumptive central nervous system" RELATED []
synonym: "ventral neurogenic region" RELATED [VHOG:0000150]
xref: AAO:0011074
xref: BILA:0000039
xref: CALOHA:TS-1212
xref: EHDAA2:0001248
xref: EHDAA:1498
xref: EHDAA:255
xref: EMAPA:16073
xref: EV:0100004
xref: FBbt:00001057 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:87657
xref: MAT:0000176
xref: MIAA:0000176
xref: NCIT:C34228
xref: TAO:0001120
xref: UMLS:C1518271 {source="ncithesaurus:Neuroectoderm"}
xref: VHOG:0000150
xref: Wikipedia:Neuroectoderm
xref: XAO:0000042
xref: ZFA:0001120
is_a: UBERON:0000923 ! germ layer
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: has_part CL:0000133 ! neurectodermal cell
property_value: UBPROP:0000003 "(...) the ability of ectoderm to produce neuronal cells is a general metazoan feature.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000150", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "neurectodermal" xsd:string
property_value: UBPROP:0000013 "we prefer neurectoderm to neural ectoderm since placodal ectoderm is not classified here" xsd:string

[Term]
id: UBERON:0002347
name: thoracic vertebra
namespace: uberon
def: "A thoracic vertebra endochondral element that is composed primarily of a bone tissue." [OBOL:automatic]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "dorsal vertebra" EXACT []
synonym: "thorax vertebra" EXACT [OBOL:automatic]
synonym: "vertebra of thorax" EXACT [OBOL:automatic]
synonym: "vertebra thoracica" EXACT []
xref: EMAPA:18011
xref: FMA:9139
xref: GAID:244
xref: MA:0000314
xref: MESH:D013904
xref: NCIT:C12798
xref: SCTID:181821009
xref: UMLS:C0039987 {source="ncithesaurus:Thoracic_Vertebra"}
xref: Wikipedia:Thoracic_vertebrae
is_a: UBERON:0002412 ! vertebra
is_a: UBERON:0003827 ! thoracic segment bone
is_a: UBERON:0004247 ! bone of dorsum
is_a: UBERON:0015008 ! thoracic vertebra endochondral element
intersection_of: UBERON:0015008 ! thoracic vertebra endochondral element
intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue
relationship: develops_from UBERON:0013507 ! thoracic vertebra cartilage element
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray90.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "Thoracic vertebrae in all species are defined as those vertebrae which also carry a pair of ribs, and lie caudal to the cervical vertebrae. In humans, they are distinguished by the presence of facets on the sides of the bodies for articulation with the heads of the ribs, and facets on the transverse processes of all, except the eleventh and twelfth, for articulation with the tubercles of the ribs" xsd:string

[Term]
id: UBERON:0002348
name: epicardium
namespace: uberon
def: "A region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart." [http://orcid.org/0000-0002-6601-2165]
comment: EDITOR_NOTE TODO - check links with UBERON:0002425 visceral serous pericardium. develops from proepicardium. WP:Epicardium -- When considered as a part of the pericardium, it is the inner layer, or visceral pericardium, continuous with the serous layer.
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "heart epicardium" EXACT []
synonym: "pericardium visceral mesothelium" RELATED [EMAPA:16589]
synonym: "visceral serous pericardium of heart" EXACT [FMA:9461]
synonym: "visceral serous pericardium proper" EXACT [FMA:9461]
xref: AAO:0010409
xref: EHDAA2:0002202
xref: FMA:9461
xref: galen:Epicardium
xref: NCIT:C13164
xref: TAO:0005057
xref: UMLS:C0225968 {source="ncithesaurus:Epicardium"}
xref: VHOG:0000119
xref: Wikipedia:Epicardium
xref: XAO:0000316
xref: ZFA:0005057
is_a: UBERON:0000481 ! multi-tissue structure
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: attaches_to UBERON:0002349 {source="FMA"} ! myocardium
relationship: develops_from UBERON:0004160 ! proepicardium
relationship: part_of UBERON:0000948 {source="multiple"} ! heart
relationship: part_of UBERON:0002425 {source="FMA-inferred"} ! visceral serous pericardium
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "External layer of the heart.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005057", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The inner layer of the pericardium that is in contact with the surface of the heart.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010409", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000009 "The visceral pericardium apparently produces the pericardial fluid, which lubricates motion between the inner and outer layers of the pericardium. During ventricular contraction, the wave of depolarization moves from endocardial to epicardial surface. [Wikipedia:Epicardium]" xsd:string

[Term]
id: UBERON:0002349
name: myocardium
namespace: uberon
def: "The middle layer of the heart, comprised mainly of striated cardiac muscle fibers." [ISBN:0-683-40008-8, MP:0005329]
comment: EDITOR_NOTE TODO - check 'Myocardum proper' in FMA. We superclass the more generic class for now. FMA has is_a muscle layer - should we add this? ZFA and BTO both have is_a 'cardiac muscle' (tissue?). But in U we also follow FMA and have cardiac muscle tissue of myocardium (there is also Fibrocollagenous connective tissue of myocardium), which would be identical (see issue-10). Note that GO also treats left/right ventricular cardiac muscle tissue synonymous with ventricular myocardium
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cardiac muscle" RELATED [ZFA:0001319]
synonym: "heart muscle" RELATED [FMA:9462, ZFA:0001319]
synonym: "heart myocardium" EXACT []
synonym: "muscle of heart" EXACT [FMA:9462]
xref: AAO:0010410
xref: BSA:0000089
xref: BTO:0000901
xref: CALOHA:TS-0440
xref: EFO:0000819
xref: EHDAA2:0004150
xref: EMAPA:32688
xref: EV:0100022
xref: FMA:9462
xref: GAID:173
xref: galen:Myocardium
xref: MA:0000164
xref: MAT:0000453
xref: MESH:D009206
xref: NCIT:C12371
xref: RETIRED_EHDAA2:0001220
xref: SCTID:362012001
xref: TAO:0001319
xref: UMLS:C0027061 {source="ncithesaurus:Myocardium"}
xref: VHOG:0000083
xref: Wikipedia:Myocardium
xref: XAO:0000065
xref: ZFA:0001319
is_a: UBERON:0005983 ! heart layer
is_a: UBERON:0018260 ! layer of muscle tissue
intersection_of: UBERON:0005983 ! heart layer
intersection_of: composed_primarily_of UBERON:0001133 ! cardiac muscle tissue
relationship: composed_primarily_of UBERON:0001133 ! cardiac muscle tissue
relationship: has_part UBERON:0002350 ! conducting system of heart
relationship: part_of UBERON:0000383 ! musculature of body
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6e/Glanzstreifen.jpg" xsd:anyURI
property_value: UBPROP:0000001 "Robust muscular tunic of the heart which forms the basic part of its walls. Its external surface is covered by the pericardium and its internal one by the endocardium. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000083", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000001 "The middle layer of the heart, consisting of cardiac muscle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010410", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000007 "myocardial" xsd:string

[Term]
id: UBERON:0002350
name: conducting system of heart
namespace: uberon
def: "The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat[GO]." [GO:0003161]
subset: efo_slim
subset: pheno_slim
subset: vertebrate_core
synonym: "cardiac conducting system" EXACT [VHOG:0001271]
synonym: "cardiac conduction system" EXACT []
synonym: "cardiac impulse conducting system" EXACT [GO:0003161]
synonym: "cardionector" EXACT []
synonym: "central conduction system" RELATED []
synonym: "complexus stimulans cordis" EXACT OMO:0003011 [FMA:9476, FMA:TA]
synonym: "heart conduction system" EXACT [GO:0003161]
synonym: "impulse conducting system" EXACT [MA:0000094]
synonym: "systema conducente cordis" EXACT OMO:0003011 [FMA:9476, FMA:TA]
xref: EFO:0003909
xref: EHDAA2:0004185
xref: EMAPA:35428
xref: EV:0100025
xref: FMA:9476
xref: MA:0000094
xref: MESH:D006329
xref: SCTID:281489000
xref: TAO:0005063
xref: VHOG:0001271
xref: ZFA:0005063
is_a: UBERON:0004493 ! cardiac muscle tissue of myocardium
is_a: UBERON:0010131 {source="FMA"} ! conducting tissue of heart
relationship: contributes_to_morphology_of UBERON:0000948 ! heart
relationship: has_part CL:0002068 {source="FMA"} ! Purkinje myocyte
relationship: has_part CL:0002073 {source="FMA"} ! transitional myocyte
relationship: has_part CL:0002074 {source="FMA"} ! myocardial endocrine cell
relationship: has_part CL:1000409 {source="FMA"} ! myocyte of sinoatrial node
relationship: has_part CL:1000410 {source="FMA"} ! myocyte of atrioventricular node
property_value: editor_note "EHDAA2 divides the system from the tissue" xsd:string
property_value: UBPROP:0000003 "The fish heart displays clear polarity of contraction in a posterior-to-anterior direction. The contraction waves originate in the sinus venosus and terminate in the conus arteriosus. The nodal phenotype persists in the inflow region of the heart, varying from the venosinus to the sinoatrial junctional areas in different species . Similar to the mammalian situation, pacemaker tissue with a lower intrinsic rhythmicity is also found at the atrioventricular junction.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001271", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003 Moorman AFM, Christoffels VM, Cardiac Chamber Formation: Development, Genes, and Evolution. Physiological Reviews (2003)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002351
name: sinoatrial node
namespace: uberon
def: "The part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node[GO]. Subdivision of conducting system of heart at the junction of the right atrium and the superior vena cava, around the sinoatrial nodal branch of right coronary artery and is continuous with the internodal tract[FMA]." [GO:0003163, Wikipedia:Sinoatrial_node]
comment: WP:Heart states: "The SA node is found in all amniotes but not in more primitive vertebrates. In these animals, the muscles of the heart are relatively continuous and the sinus venosus coordinates the beat which passes in a wave through the remaining chambers. Indeed, since the sinus venosus is incorporated into the right atrium in amniotes, it is likely homologous with the SA node. In teleosts, with their vestigial sinus venosus, the main centre of coordination is, instead, in the atrium.". Note however that ZFA has SA node.
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cardiac pacemaker" EXACT [FMA:9477]
synonym: "Koch's node" EXACT [FMA:9477]
synonym: "node of Keith-Flack" EXACT [FMA:9477]
synonym: "nodus sinuatrialis" EXACT OMO:0003011 [FMA:9477, FMA:TA]
synonym: "nodus sinuatrialis" RELATED OMO:0003011 [Wikipedia:Sinoatrial_node]
synonym: "SA nodal muscle tissue" EXACT [FMA:9477]
synonym: "SA node" EXACT [FMA:9477]
synonym: "sinoatrial node" EXACT [FMA:9477]
synonym: "sinu-atrial node" EXACT [FMA:9477]
synonym: "sinuatrial nodal muscle tissue" EXACT [FMA:9477]
synonym: "sinuatrial node" EXACT [FMA:9477]
synonym: "sinus node" EXACT [FMA:9477]
synonym: "sinus node of Keith and Flack" EXACT [FMA:9477]
xref: BTO:0004358
xref: EHDAA2:0004184
xref: EMAPA:35772
xref: FMA:9477
xref: GAID:561
xref: MA:0000097
xref: MESH:D012849
xref: NCIT:C33555
xref: SCTID:277687007
xref: TAO:0005069
xref: UMLS:C0037189 {source="ncithesaurus:Sinoatrial_Node"}
xref: Wikipedia:Sinoatrial_node
xref: ZFA:0005069
is_a: UBERON:0003379 ! cardiac muscle of right atrium
is_a: UBERON:0010131 {source="cjm"} ! conducting tissue of heart
relationship: capable_of GO:0002027 ! regulation of heart rate
relationship: capable_of_part_of GO:0060048 ! cardiac muscle contraction
relationship: contributes_to_morphology_of UBERON:0002350 ! conducting system of heart
relationship: in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0002350 {source="ZFA"} ! conducting system of heart
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d2/Sinoatrial_node_low_mag.jpg" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/de/Sinoatrial_node_2_low_mag.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002352
name: atrioventricular node
namespace: uberon
def: "An area of conducting tissue between the atria and the ventricles of the heart that conducts the normal electrical impulse from the atria to the ventricles." [UBERON:cjm, Wikipedia:Atrioventricular_node]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "A-V node" RELATED [EMAPA:35153]
synonym: "Aschoff-Tawara node" EXACT [FMA:9478]
synonym: "atrio-ventricular node" RELATED [EMAPA:35153]
synonym: "atrioventricular nodal muscle tissue" EXACT [FMA:9478]
synonym: "atriovetricular node" RELATED [TAO:0005070]
synonym: "AV nodal muscle tissue" EXACT [FMA:9478]
synonym: "AV node" EXACT [FMA:9478, MA:0000095]
synonym: "downstream pacemaker" RELATED [ZFA:0005070]
synonym: "node of Tawara" EXACT [FMA:9478]
synonym: "nodus atrioventricularis" EXACT OMO:0003011 [FMA:TA]
synonym: "nodus atrioventricularis" RELATED OMO:0003011 [Wikipedia:Atrioventricular_node]
xref: BTO:0005689
xref: EFO:0000276
xref: EHDAA2:0004183
xref: EMAPA:35153
xref: FMA:9478
xref: GAID:558
xref: MA:0000095
xref: MAT:0000498
xref: MESH:D001283
xref: NCIT:C32161
xref: SCTID:277688002
xref: TAO:0005070
xref: UMLS:C0004247 {source="ncithesaurus:Atrioventricular_Node"}
xref: VHOG:0001474
xref: Wikipedia:Atrioventricular_node
xref: ZFA:0005070
is_a: UBERON:0004491 ! cardiac muscle tissue of interatrial septum
is_a: UBERON:0004493 ! cardiac muscle tissue of myocardium
is_a: UBERON:0010131 {source="cjm"} ! conducting tissue of heart
relationship: connected_to UBERON:0002085 ! interatrial septum
relationship: connected_to UBERON:0005979 ! crista terminalis
relationship: contributes_to_morphology_of UBERON:0002350 ! conducting system of heart
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0002350 ! conducting system of heart
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/50/ConductionsystemoftheheartwithouttheHeart.png" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/92/Gray501.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "Three major adaptations, or 'novel cardiac components', that were not present in the ancestor chordate heart tube can be distinguished in the lower vertebrate heart: the atrium, ventricle, and possibly the muscular sinus venosus. Furthermore, within the ventricular component a compact outer myocardial component and an interiorly localized extensive trabecular component can be distinguished. The specific activation of the ventricle adds to its complexity as follows. The depolarizing impulse travels rapidly from the atrioventricular node toward the apex and then toward the conal region, achieving activation from apex to base.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001474", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003 Moorman AFM, Christoffels VM, Cardiac Chamber Formation: Development, Genes, and Evolution. Physiological Reviews (2003)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002354
name: cardiac Purkinje fiber
namespace: uberon
alt_id: UBERON:0004147
def: "The cardiac Purkinje fiber is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." [GO:0003165]
subset: pheno_slim
subset: uberon_slim
synonym: "cardiac Purkinje fiber" EXACT [BTO:0001735, GO:0003165]
synonym: "heart Purkinje fiber" RELATED [BTO:0001735]
synonym: "myofibra conducens cardiacus" EXACT OMO:0003011 []
synonym: "Purkinje fiber" EXACT [FMA:9492, MA:0000096]
synonym: "subendocardial branch" EXACT [Wikipedia:Purkinje_fiber]
xref: BTO:0001735
xref: EMAPA:35718
xref: FMA:9492
xref: GAID:560
xref: MA:0000096
xref: MESH:D011690
xref: NCIT:C33430
xref: UMLS:C0034144 {source="ncithesaurus:Purkinje_Fiber"}
xref: Wikipedia:Purkinje_fiber
is_a: UBERON:0010131 {source="FMA"} ! conducting tissue of heart
is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle
relationship: contributes_to_morphology_of UBERON:0002350 ! conducting system of heart
relationship: has_part CL:0002068 {source="FMA"} ! Purkinje myocyte
relationship: part_of UBERON:8000009 {source="https://github.com/obophenotype/uberon/issues/1785", source="https://orcid.org/0000-0001-5208-3432", source="https://orcid.org/0000-0002-9791-0064"} ! Purkinje fiber network
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray498.png" xsd:anyURI

[Term]
id: UBERON:0002355
name: pelvic region of trunk
namespace: uberon
def: "The lower segment of the trunk, inferioposterior to the abdomen proper, in the transition area between the trunk and the lower limbs." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/720, Wikipedia:Pelvis]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "lesser pelvis" EXACT [FMA:9578]
synonym: "pelvic region" EXACT []
synonym: "pelvis" EXACT [FMA:9578, MA:0000030]
synonym: "pelvis region" EXACT []
synonym: "true pelvis" EXACT [FMA:9578]
xref: BTO:0001006
xref: CALOHA:TS-2227
xref: EFO:0002805
xref: EMAPA:35931
xref: EV:0100012
xref: FMA:9578
xref: GAID:87
xref: galen:Pelvis
xref: MA:0000030
xref: MESH:D010388
xref: NCIT:C12767
xref: SCTID:229765004
xref: UMLS:C0030797 {source="ncithesaurus:Pelvis"}
xref: Wikipedia:Pelvis
is_a: UBERON:0000475 ! organism subdivision
relationship: has_part UBERON:0007832 ! pelvic girdle skeleton
relationship: part_of UBERON:0002417 ! abdominal segment of trunk
property_value: UBPROP:0000007 "pelvic" xsd:string
property_value: UBPROP:0000012 "MA and FMA differ in what they consider to be parts of the pelvis. MA includes ureter, urethra, urinary bladder, reproductive organs" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0002357
name: serous pericardium
namespace: uberon
def: "Serous membrane which is divided into parietal and visceral serous pericardium." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Serous_pericardium]
subset: uberon_slim
synonym: "pericardium serosum" RELATED OMO:0003011 [Wikipedia:Serous_pericardium]
synonym: "serous portion of pericardium" EXACT [FMA:9582]
xref: EMAPA:19030
xref: FMA:9582
xref: MA:0002739
xref: SCTID:243954002
xref: Wikipedia:Serous_pericardium
is_a: UBERON:0000042 ! serous membrane
relationship: attaches_to UBERON:0002359 {source="FMA"} ! fibrous pericardium
relationship: has_part UBERON:0002408 ! parietal serous pericardium
relationship: has_part UBERON:0002425 ! visceral serous pericardium
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0002406 {source="FMA"} ! pericardial sac

[Term]
id: UBERON:0002358
name: peritoneum
namespace: uberon
def: "A serous membrane that lines the peritoneal cavity[VHOG,modified]." [VHOG:0001257]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "peritonaeum" RELATED [VHOG:0001257]
xref: AAO:0010814
xref: BTO:0001472
xref: CALOHA:TS-2072
xref: EV:0100087
xref: FMA:9584
xref: GAID:18
xref: galen:Peritoneum
xref: MA:0000449
xref: MESH:D010537
xref: NCIT:C12770
xref: TAO:0005120
xref: UMLS:C0031153 {source="ncithesaurus:Peritoneum"}
xref: VHOG:0001257
xref: Wikipedia:Peritoneum
xref: XAO:0000139
xref: ZFA:0005120
is_a: UBERON:0000042 ! serous membrane
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0035820 ! peritoneal sac
relationship: part_of UBERON:0003697 {source="MP"} ! abdominal wall
relationship: part_of UBERON:0035820 ! peritoneal sac
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png" xsd:anyURI
property_value: editor_note "TODO - in ZFA is_a epithelium" xsd:string
property_value: UBPROP:0000001 "An epithelium that lines the peritoneal cavity.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005120", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Serous membrane that forms the lining of the abdominal cavity or the coelom. It covers most of the intra-abdominal organs, supports the abdominal organs, and serves as a conduit for their blood and lymph vessels and nerves. It is composed of a layer of mesothelium.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010814", ontology="AAO", source="AAO:JMG"}
property_value: UBPROP:0000007 "peritoneal" xsd:string
property_value: UBPROP:0000012 "todo: check MA/EMAPA." xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0002359
name: fibrous pericardium
namespace: uberon
def: "Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA]." [FMA:9586]
subset: organ_slim
subset: uberon_slim
synonym: "fibrous portion of pericardium" EXACT []
synonym: "pericardium fibrosum" RELATED OMO:0003011 [Wikipedia:Fibrous_pericardium]
xref: EMAPA:19029
xref: FMA:9586
xref: MA:0002738
xref: SCTID:243953008
xref: Wikipedia:Fibrous_pericardium
is_a: UBERON:0000094 {source="FMA"} ! membrane organ
is_a: UBERON:0005181 ! thoracic segment organ
relationship: composed_primarily_of UBERON:0006815 {source="WP"} ! areolar connective tissue
relationship: continuous_with UBERON:0002408 ! parietal serous pericardium
relationship: part_of UBERON:0002407 {source="FMA"} ! pericardium
property_value: UBPROP:0000010 "most superficial part of pericardium; continuous with the outer adventitial layer of the neighboring great blood vessels. [Wikipedia:Pericardium]" xsd:string

[Term]
id: UBERON:0002365
name: exocrine gland
namespace: uberon
def: "A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas." [Wikipedia:Exocrine_gland]
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "ducted gland" EXACT [AEO:0000097]
synonym: "glandula exocrina" EXACT OMO:0003011 [Wikipedia:Exocrine_gland]
xref: AEO:0000097
xref: BTO:0000765
xref: CALOHA:TS-2012
xref: EHDAA2:0003097
xref: EMAPA:35327
xref: FMA:9596
xref: GAID:34
xref: MA:0002564
xref: MESH:D005088
xref: NCIT:C12712
xref: SCTID:115976003
xref: UMLS:C0015282 {source="ncithesaurus:Exocrine_Gland"}
xref: Wikipedia:Exocrine_gland
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0002530 ! gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0002330 ! exocrine system
relationship: has_part UBERON:0000058 ! duct
relationship: part_of UBERON:0002330 ! exocrine system
property_value: editor_note "Currently this is logically defined by the system it belongs to, but a better system may be base this on presence/absence of ducts. However, the dual nature of the liver should be taken into consideration here. Consider adding subclasses" xsd:string

[Term]
id: UBERON:0002368
name: endocrine gland
namespace: uberon
def: "Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]." [Wikipedia:Endocrine_gland]
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "ductless gland" EXACT [AEO:0000098]
synonym: "ductless gland" RELATED [Wikipedia:Ductless_gland]
synonym: "glandula endocrina" EXACT []
synonym: "glandulae endocrinae" RELATED OMO:0003011 [Wikipedia:Endocrine_gland]
xref: AEO:0000098
xref: BTO:0001488
xref: CALOHA:TS-1300
xref: EHDAA2:0003098
xref: EMAPA:35999
xref: FMA:9602
xref: GAID:335
xref: MA:0002563
xref: MESH:D004702
xref: NCIT:C12704
xref: SCTID:40818001
xref: UMLS:C0014133 {source="ncithesaurus:Endocrine_Gland"}
xref: Wikipedia:Endocrine_gland
is_a: UBERON:0002530 ! gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0000949 ! endocrine system
relationship: capable_of GO:0046879 ! hormone secretion
relationship: part_of UBERON:0000949 ! endocrine system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Illu_endocrine_system.png" xsd:anyURI

[Term]
id: UBERON:0002371
name: bone marrow
namespace: uberon
def: "The soft tissue that fills the cavities of bones." [MGI:cwg, MP:0002397]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "medulla of bone" RELATED [BTO:0000141]
synonym: "medulla ossea" EXACT OMO:0003011 [BTO:0000141, FMA:9608]
synonym: "medulla ossium" EXACT OMO:0003011 [BTO:0000141, Wikipedia:Bone_marrow]
synonym: "medullary bone" RELATED []
xref: AAO:0011007
xref: BTO:0000141
xref: BTO:0000829
xref: CALOHA:TS-0087
xref: EFO:0000868
xref: EMAPA:32760
xref: EV:0100046
xref: FMA:9608
xref: GAID:1287
xref: galen:BoneMarrow
xref: MA:0000134
xref: MAT:0000084
xref: MESH:D001853
xref: MIAA:0000084
xref: NCIT:C12431
xref: SCTID:421320006
xref: UMLS:C0005953 {source="ncithesaurus:Bone_Marrow"}
xref: VHOG:0001218
xref: Wikipedia:Bone_marrow
xref: XAO:0000123
is_a: UBERON:0000479 ! tissue
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000479 ! tissue
intersection_of: has_part UBERON:0012429 ! hematopoietic tissue
intersection_of: part_of UBERON:0001474 ! bone element
relationship: has_part CL:0002092 ! bone marrow cell
relationship: has_part UBERON:0012429 ! hematopoietic tissue
relationship: part_of UBERON:0001474 ! bone element
relationship: part_of UBERON:0002390 {source="FMA", source="MA"} ! hematopoietic system
relationship: part_of UBERON:0002405 ! immune system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg" xsd:anyURI
property_value: editor_note "consider placement of NCIT:C53466 medullary bone" xsd:string
property_value: editor_note "TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "The bone marrow is the hematopoietic organ in all vertebrates but fishes, in which hematopoiesis occurs in the kidney.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001218", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.22.010605.093317 Hartenstein V, Blood Cells and Blood Cell Development in the Animal Kingdom. Annual Review of Cell and Developmental Biology (2006)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000009 "In adults, marrow in large bones produces new blood cells[Wikipedia:Bone_marrow]" xsd:string

[Term]
id: UBERON:0002376
name: cranial muscle
namespace: uberon
alt_id: UBERON:0003899
def: "Any skeletal muscle that is part of the head region." [http://orcid.org/0000-0002-6601-2165]
comment: defined generically so could in theory encompass FBbt:00003260 'skeletal muscle of head', or the muscle of a starfish Aristotle's lantern, but we restrict this to craniates. Skeletal muscles of the head originate from the non-segmented head mesoderm (Noden, 1983; Wachtler et al., 1984)
subset: efo_slim
subset: human_reference_atlas
subset: uberon_slim
subset: vertebrate_core
synonym: "adult head muscle organ" NARROW [OBOL:automatic]
synonym: "cephalic muscle" EXACT [ZFA:0001652]
synonym: "cephalic musculature" EXACT []
synonym: "cranial muscle" RELATED [ZFA:0001652]
synonym: "head muscle" EXACT [MA:0000578]
synonym: "head muscle organ" EXACT [OBOL:automatic]
synonym: "head muscles" RELATED []
synonym: "muscle of head" EXACT [FMA:9616]
synonym: "muscle organ of adult head" EXACT [OBOL:automatic]
synonym: "muscle organ of head" EXACT [OBOL:automatic]
synonym: "musculus caput" EXACT []
xref: AAO:0000107
xref: BTO:0000021
xref: EFO:0003524
xref: EHDAA2:0000322
xref: EMAPA:18172
xref: FMA:9616
xref: MA:0000578
xref: SCTID:244718003
xref: ZFA:0001652
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0010959 ! craniocervical muscle
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: attaches_to UBERON:0003129 ! skull
intersection_of: part_of UBERON:0000033 ! head
relationship: attaches_to UBERON:0003129 ! skull
relationship: develops_from UBERON:0006904 {source="EHDAA2-abduced"} ! head mesenchyme from mesoderm
relationship: has_developmental_contribution_from UBERON:0002342 {gci_relation="part_of", gci_filler="NCBITaxon:7742", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! neural crest
relationship: part_of UBERON:0004461 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! skeletal musculature of head
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002377
name: muscle of neck
namespace: uberon
def: "Any muscle that is part of the cervical (neck) region." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "muscle organ of neck" EXACT [OBOL:automatic]
synonym: "muscle organ of neck (volume)" EXACT [OBOL:automatic]
synonym: "neck (volume) muscle organ" EXACT [OBOL:automatic]
synonym: "neck muscle" EXACT []
synonym: "neck muscle organ" EXACT [OBOL:automatic]
xref: EMAPA:36050
xref: FMA:9617
xref: GAID:149
xref: MA:0000587
xref: MESH:D009334
xref: NCIT:C33163
xref: UMLS:C0027532 {source="ncithesaurus:Neck_Muscle"}
is_a: UBERON:0010959 ! craniocervical muscle
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0000974 ! neck
relationship: part_of UBERON:0004465 {source="prolog"} ! musculature of neck
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002378
name: muscle of abdomen
namespace: uberon
def: "Muscle (organ) which is a part of the abdomen. Examples: external oblique, rectus abdominis." [Wikipedia:Abdominal_muscle]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "abdomen muscle" EXACT []
synonym: "abdomen muscle organ" EXACT [OBOL:automatic]
synonym: "abdominal muscle" EXACT []
synonym: "abdominal wall muscle" EXACT []
synonym: "abdominal wall musculature" RELATED [EMAPA:35103]
synonym: "muscle organ of abdomen" EXACT [OBOL:automatic]
xref: BTO:0001261
xref: EMAPA:35103
xref: FMA:9620
xref: GAID:89
xref: MA:0000520
xref: MESH:D000009
xref: NCIT:C32040
xref: SCTID:361352008
xref: UMLS:C0000739 {source="ncithesaurus:Abdominal_Muscle"}
xref: Wikipedia:Abdominal_muscle
is_a: UBERON:0003833 ! abdominal segment muscle
is_a: UBERON:0005172 ! abdomen element
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0002343 {source="prolog"} ! abdomen musculature
relationship: part_of UBERON:0003697 ! abdominal wall
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002384
name: connective tissue
namespace: uberon
def: "Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/23, PSPUB:0000170, VSAO:0000017]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "Bindegewebe" RELATED [BTO:0000421]
synonym: "portion of connective tissue" EXACT [FMA:9640]
synonym: "textus connectivus" EXACT []
xref: AAO:0000098
xref: BTO:0000421
xref: CALOHA:TS-2009
xref: EFO:0000952
xref: EMAPA:35251
xref: FMA:9640
xref: GAID:100
xref: galen:ConnectiveTissue
xref: MA:0000011
xref: MAT:0000301
xref: MESH:D003238
xref: MIAA:0000301
xref: NCIT:C12374
xref: SCTID:361919005
xref: TAO:0001641
xref: UMLS:C0009780 {source="ncithesaurus:Connective_Tissue"}
xref: VSAO:0000017
xref: XAO:0001017
xref: ZFA:0001632
is_a: UBERON:0000479 ! tissue
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "One of the four types of tissue in traditional classifications. It is largely a category of exclusion rather than one with a precise definition, but there are certain characteristics shared by all or most tissues in this category, such as involvement in structure and support, derived from mesoderm, and characterized largely by the traits of non-living tissue.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000098", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000001 "Portion of tissue that consists of mesodermally derived cells and intercellular matrix comprised of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001641", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000001 "Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000017", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"}
property_value: UBPROP:0000012 "MA also has set of connective tissues" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0002385
name: muscle tissue
namespace: uberon
def: "Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]." [GO:0060537, https://sourceforge.net/tracker/index.php?func=detail&aid=2801266&group_id=36855&atid=440764, Wikipedia:Muscle_tissue]
comment: Vertebrate muscle is categorized into three major muscle types defined by their structural and functional properties: skeletal, cardiac and smooth. In Dmel the counterparts are somatic, heart/cardiac and visceral. Here we take a cell type based approach.
subset: uberon_slim
synonym: "muscular tissue" EXACT SENSU []
synonym: "portion of muscle tissue" EXACT [FMA:9641]
synonym: "textus muscularis" EXACT []
xref: AAO:0000306
xref: AEO:0000122
xref: CALOHA:TS-0642
xref: EHDAA2:0003122
xref: EMAPA:32715
xref: FMA:9641
xref: galen:MuscleTissue
xref: MA:0002437
xref: MESH:D009132
xref: NCIT:C12435
xref: SCTID:91727004
xref: UMLS:C2328219 {source="ncithesaurus:Muscle_Tissue"}
xref: Wikipedia:Muscle_tissue
is_a: UBERON:0000479 ! tissue
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000479 ! tissue
intersection_of: composed_primarily_of CL:0000187 ! muscle cell
disjoint_from: UBERON:0003714 ! neural tissue
relationship: capable_of GO:0006936 ! muscle contraction
relationship: composed_primarily_of CL:0000187 ! muscle cell
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0001015 ! musculature
property_value: RO:0002171 UBERON:0003714
property_value: UBPROP:0000001 "One of the four types of tissue in traditional classifications. Tissue that contains cells with contractile filaments that move past each other and change the size of the cell. Muscle tissue also is separated into three distinct categories.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000306", ontology="AAO", source="AAO:LAP"}

[Term]
id: UBERON:0002390
name: hematopoietic system
namespace: uberon
def: "Anatomical system that is involved in the production of hematopoietic cells." [Wikipedia:Haematopoiesis]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "Blutbildungssystem" RELATED [BTO:0000570]
synonym: "haematological system" EXACT []
synonym: "haematopoietic system" RELATED []
synonym: "haemopoietic system" EXACT []
synonym: "hematological system" RELATED []
synonym: "hematolymphoid system" RELATED []
synonym: "hemopoietic system" RELATED []
synonym: "organa haemopoietica" EXACT []
xref: AAO:0011002
xref: BTO:0000570
xref: CALOHA:TS-0449
xref: EFO:0000798
xref: EMAPA:35402
xref: EV:0100045
xref: FMA:9667
xref: GAID:1008
xref: MA:0002434
xref: MAT:0000022
xref: MESH:D006413
xref: MIAA:0000022
xref: NCIT:C12909
xref: SCTID:362587009
xref: TAO:0005023
xref: UMLS:C0018957 {source="ncithesaurus:Hematopoietic_System"}
xref: VHOG:0001624
xref: Wikipedia:Haematopoiesis
xref: XAO:0000122
xref: ZFA:0005023
is_a: UBERON:0000467 ! anatomical system
is_a: UBERON:0004120 ! mesoderm-derived structure
disjoint_from: UBERON:0002405 ! immune system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: develops_from UBERON:0003061 {evidence="definitional"} ! blood island
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
relationship: part_of UBERON:0002193 {source="FMA"} ! hemolymphoid system
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anatomical system that consists of the blood and blood forming tissues.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011002", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "Zebrafish developmental hematopoiesis shows close correspondence to the development of the mammalian hematopoietic system and is regulated by conserved molecular pathways.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001624", ontology="VHOG", source="DOI:10.1016/j.coph.2010.05.004 Ellett F, Lieschke GJ, Zebrafish as a model for vertebrate hematopoiesis. Current Opinion in Pharmacology (2010)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "hematopoietic" xsd:string
property_value: UBPROP:0000008 "In humans this is primarily the bone marrow, spleen, tonsils, and lymph nodes" xsd:string {source="WP"}

[Term]
id: UBERON:0002394
name: bile duct
namespace: uberon
def: "Any of the ducts that form the biliary tree, carrying bile from the liver to the small intestine." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Bile_duct]
subset: pheno_slim
subset: uberon_slim
synonym: "bile tube" RELATED []
synonym: "biliary duct" RELATED [FMA:9706]
synonym: "gall duct" RELATED [BTO:0000122]
synonym: "hepatic duct" RELATED INCONSISTENT [ZFA:0001100]
xref: AAO:0011019
xref: BTO:0000122
xref: CALOHA:TS-0075
xref: EHDAA2:0000741
xref: EMAPA:35171
xref: EV:0100091
xref: FMA:9706
xref: GAID:280
xref: MA:0000354
xref: MESH:D001652
xref: NCIT:C12376
xref: SCTID:276157007
xref: TAO:0001100
xref: UMLS:C0005400 {source="ncithesaurus:Bile_Duct"}
xref: VHOG:0000212
xref: Wikipedia:Bile_duct
xref: XAO:0000134
xref: ZFA:0001100
is_a: UBERON:0000025 ! tube
is_a: UBERON:0003928 ! digestive system duct
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000058 ! duct
intersection_of: part_of UBERON:0001173 ! biliary tree
relationship: channel_for UBERON:0001970 ! bile
relationship: contributes_to_morphology_of UBERON:0001173 ! biliary tree
relationship: develops_from UBERON:0008835 {source="XAO"} ! hepatic diverticulum
relationship: part_of UBERON:0001173 {source="EMAPA", source="MA"} ! biliary tree
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI
property_value: UBPROP:0000001 "A duct that carries bile from the liver to the intestine." xsd:string {source="ZFA:0001100, ZFA:curator"}
property_value: UBPROP:0000001 "Any of the excretory ducts in the liver that convey bile between the liver and the intestine. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000212", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/bile+duct"}
property_value: UBPROP:0000003 "(...) the amphibian liver has characteristics in common with both fish and terrestrial vertebrates. (...) The histological structure of the liver is similar to that in other vertebrates, with hepatocytes arranged in clusters and cords separated by a meshwork of sinusoids and the presence of the traditional triad of portal venule, hepatic arteriole, and bile duct.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000212", ontology="VHOG", source="DOI:10.1053/ax.2000.7133 Crawshaw GJ, Weinkle TK, Clinical and pathological aspects of the amphibian liver. Seminars in Avian and Exotic Pet Medicine (2000)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "we place the ZFA class here as this fits its textual definition and child nodes. We may recommend a label change for ZFA" xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0002396
name: vomer
namespace: uberon
def: "The triangular flat bone of the nasal septum." [ISBN:0-683-40008-8, MP:0000098]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "prevomer" RELATED [TAO:0000308]
synonym: "vomer bone" EXACT []
xref: AAO:0000633
xref: FMA:9710
xref: MA:0001496
xref: MESH:D055172 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C33888
xref: SCTID:272678009
xref: TAO:0000308
xref: UMLS:C0242403 {source="ncithesaurus:Vomer"}
xref: Wikipedia:Vomer
xref: ZFA:0000308
is_a: UBERON:0008001 {source="FMA"} ! irregular bone
is_a: UBERON:0011597 ! bone of upper jaw
is_a: UBERON:0012071 ! palate bone
relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone
relationship: connected_to UBERON:0001679 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! ethmoid bone
relationship: contributes_to_morphology_of UBERON:0011156 ! facial skeleton
relationship: part_of UBERON:0011085 ! palatoquadrate arch
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Dermal bone that underlies the mesethmoid and inserts in a fossa on the anteroventral surface of the parasphenoid.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000308", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Paired, palatal bones of intramembranous origin that lie ventral to the olfactory region and help to floor the nasal capsules.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000633", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000002 "relationship loss: overlaps autopalatine-vomer joint (TAO:0001784)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000308", ontology="TAO"}
property_value: UBPROP:0000002 "relationship loss: overlaps mesethmoid-vomer joint (TAO:0001680)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000308", ontology="TAO"}
property_value: UBPROP:0000003 "In bony fish, the vomers are flattened, paired, bones forming the anterior part of the roof of the mouth, just behind the premaxillary bones. In many species, they have teeth, supplementing those in the jaw proper; in some extinct species the teeth on the vomers were actually larger than the primary set. In amphibians and reptiles, the vomers become narrower, due to the presence of the enlarged choanae (the inner part of the nostrils) on either side, and they may extend further back in the jaw. They are typically small in birds, where they form the upper hind part of the beak, again being located between the choanae. In mammals, the vomers have become narrower still, and are fused into a single, vertically oriented bone. The development of the hard palate beneath the vomer means that the bone is now located in a nasal chamber, separate from the mouth[WP]" xsd:string {source="Wikipedia:Vomer#In_other_animals"}
property_value: UBPROP:0000005 "The vomer is paired in some taxa (e.g., Amia) while unpaired in others (e.g., teleosts).[TAO]" xsd:string {date_retrieved="2012-09-06", external_class="TAO:0000308", ontology="TAO", source="Curator"}

[Term]
id: UBERON:0002400
name: parietal pleura
namespace: uberon
def: "The outer serous membrane of the pulmonary pleural." [UBERON:cjm, Wikipedia:Pulmonary_pleurae]
comment: the part of the pleura external to the visceral pleura. It lines the inner surface of the chest wall, covers the diaphragm, and is reflected over the structures occupying the middle of the thorax
subset: pheno_slim
subset: uberon_slim
synonym: "pleura parietalis" RELATED OMO:0003011 [Wikipedia:Parietal_pleura]
xref: EMAPA:16776
xref: FMA:9733
xref: MA:0002488
xref: NCIT:C33273
xref: SCTID:361998003
xref: UMLS:C0225777 {source="ncithesaurus:Parietal_Pleura"}
xref: VHOG:0001495
xref: Wikipedia:Parietal_pleura
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: adjacent_to UBERON:0002224 ! thoracic cavity
intersection_of: part_of UBERON:0000977 ! pleura
relationship: adjacent_to UBERON:0002224 ! thoracic cavity
relationship: contributes_to_morphology_of UBERON:0000977 ! pleura
relationship: innervated_by UBERON:0003727 ! intercostal nerve
relationship: part_of UBERON:0000977 ! pleura

[Term]
id: UBERON:0002401
name: visceral pleura
namespace: uberon
def: "The inner serous membrane of the pulmonary pleural. The visceral pleura lines the lungs." [UBERON:cjm, Wikipedia:Pulmonary_pleurae]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "lung mesothelium" RELATED [EHDAA2:0002205]
synonym: "lung pleura" RELATED []
synonym: "pleura pulmonalis" EXACT OMO:0003011 [FMA:9734, FMA:TA]
synonym: "pleura visceralis" EXACT OMO:0003011 [Wikipedia:Visceral_pleura]
synonym: "pleura visceralis (pulmonalis)" EXACT []
synonym: "pulmonary pleura" RELATED INCONSISTENT [FMA:9734]
synonym: "pulmonary visceral pleura" EXACT []
xref: EHDAA2:0002205
xref: EMAPA:16777
xref: FMA:9734
xref: MA:0002489
xref: NCIT:C33881
xref: SCTID:361997008
xref: UMLS:C0225776 {source="ncithesaurus:Visceral_Pleura"}
xref: VHOG:0001496
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0022350 ! visceral serous membrane
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: adjacent_to UBERON:0002048 ! lung
intersection_of: part_of UBERON:0000977 ! pleura
relationship: adjacent_to UBERON:0002048 ! lung
relationship: attaches_to UBERON:0008946 ! lung parenchyma
relationship: contributes_to_morphology_of UBERON:0000977 ! pleura
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0000977 ! pleura
relationship: part_of UBERON:0002048 {source="FMA"} ! lung
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Each lung is invested by an exceedingly delicate serous membrane, the pleura, which is arranged in the form of a closed invaginated sac. A portion of the serous membrane covers the surface of the lung and dips into the fissures between its lobes; it is called the pulmonary pleura (or visceral pleura). The visceral pleura is attached directly to the lungs[Wikipedia:Visceral_pleura]." xsd:string {source="Wikipedia:Visceral_pleura"}
property_value: UBPROP:0000012 "FMA treats this as part of the lungs" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0002402
name: pleural cavity
namespace: uberon
def: "The fluid-filled cavity that lies between the visceral and parietal pleurae." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Pleural_cavity]
subset: pheno_slim
subset: uberon_slim
synonym: "cavitas pleuralis" EXACT OMO:0003011 [Wikipedia:Pleural_cavity]
synonym: "cavitum pleuralae" RELATED OMO:0003011 [Wikipedia:Pleural_cavity]
synonym: "cavitum pleurale" RELATED OMO:0003011 [Wikipedia:Pleural_cavity]
xref: BTO:0004422
xref: EHDAA2:0001475
xref: EMAPA:16773
xref: EMAPA:16774
xref: FMA:9740
xref: GAID:95
xref: MA:0000055
xref: MESH:D035422
xref: NCIT:C12840
xref: SCTID:361999006
xref: UMLS:C0178802 {source="ncithesaurus:Pleural_Cavity"}
xref: VHOG:0000581
xref: Wikipedia:Pleural_cavity
is_a: UBERON:0035809 ! serous cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0009778 ! pleural sac
relationship: adjacent_to UBERON:0002400 ! parietal pleura
relationship: adjacent_to UBERON:0002401 ! visceral pleura
relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom
relationship: luminal_space_of UBERON:0009778 ! pleural sac
relationship: part_of UBERON:0009778 ! pleural sac
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png" xsd:anyURI
property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart [of other tetrapods] is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes). Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000581", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000009 "The contraction of the diaphragm creates a negative pressure within the pleural cavity which forces the lungs to expand resulting in passive exhalation and active inhalation. This breathing process can be made forceful through the contraction of the external intercostal muscles which forces the rib cage to expand and add to the negative pressure in the pleural cavity causing the lungs to fill with air. The fluid in the cavity provides lubrication and cushioning" xsd:string
property_value: UBPROP:0000012 "the EHDAA2 class of the same is not equivalent. See https://github.com/obophenotype/uberon/issues/86" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0002405
name: immune system
namespace: uberon
def: "Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." [Wikipedia:Immune_system]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
xref: AAO:0011003
xref: BILA:0000104
xref: BTO:0005810
xref: FMA:9825
xref: GAID:328
xref: MA:0002711
xref: MESH:D007107
xref: NCIT:C12735
xref: SCTID:362590003
xref: TAO:0001159
xref: UMLS:C0020962 {source="ncithesaurus:Immune_System"}
xref: VHOG:0001247
xref: Wikipedia:Immune_system
xref: XAO:0003152
xref: ZFA:0001159
is_a: UBERON:0015203 ! non-connected functional system
disjoint_from: UBERON:0002416 ! integumental system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: capable_of GO:0002376 ! immune system process
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: protects UBERON:0000468 ! multicellular organism
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "The antibody-based immune system defined by the presence of the major histocompatibility complex (MHC), T cell receptor (TCR), B cell receptor (BCR) or recombination activating genes (RAGs) is known beginning from jawed fishes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001247", ontology="VHOG", source="PMID:21046016 Dzik JM, The ancestry and cumulative evolution of immune reactions. Acta biochimica Polonica (2010)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002406
name: pericardial sac
namespace: uberon
def: "A double-walled sac containing the heart and the roots of the great vessels." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Pericardium]
subset: uberon_slim
subset: vertebrate_core
synonym: "pericardium" RELATED []
xref: FMA:9868
xref: RETIRED_EHDAA2:0001443
xref: SCTID:361326002
xref: TAO:0000054
is_a: UBERON:0005181 ! thoracic segment organ
is_a: UBERON:0005906 ! serous sac
intersection_of: UBERON:0005906 ! serous sac
intersection_of: has_part UBERON:0001074 ! pericardial cavity
intersection_of: has_part UBERON:0002357 ! serous pericardium
relationship: has_part UBERON:0001074 ! pericardial cavity
relationship: has_part UBERON:0002357 ! serous pericardium
relationship: part_of UBERON:0002407 ! pericardium
relationship: surrounded_by UBERON:0002359 {source="FMA"} ! fibrous pericardium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png" xsd:anyURI

[Term]
id: UBERON:0002407
name: pericardium
namespace: uberon
def: "The combination of pericardial sac (a double-walled sac containing the heart and the roots of the great vessels) plus fibrous pericardium." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Pericardium]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
xref: AAO:0010817
xref: BSA:0000090
xref: BTO:0000717
xref: CALOHA:TS-0761
xref: EFO:0000820
xref: EHDAA:5376
xref: EMAPA:16133
xref: EV:0100023
xref: FMA:9869
xref: GAID:569
xref: galen:Pericardium
xref: MA:0000099
xref: MAT:0000454
xref: MESH:D010496
xref: NCIT:C13005
xref: RETIRED_EHDAA2:0001443
xref: SCTID:181295003
xref: TAO:0000054
xref: UMLS:C0031050 {source="ncithesaurus:Pericardium"}
xref: VHOG:0001280
xref: Wikipedia:Pericardium
xref: XAO:0004182
xref: ZFA:0000054
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000481 ! multi-tissue structure
relationship: has_part UBERON:0002359 ! fibrous pericardium
relationship: has_part UBERON:0002406 ! pericardial sac
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0015410 {source="MA"} ! heart plus pericardium
relationship: surrounds UBERON:0002349 ! myocardium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Peritoneum that surrounds the heart.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010817", ontology="AAO", source="AAO:JMG"}
property_value: UBPROP:0000007 "pericardial" xsd:string
property_value: UBPROP:0000012 "In GO the concept of pericardium is developmental implicitly epithelial, but here it represents a multi-tissue structure encompassing the sac (epithelium plus connective) and cavity" xsd:string {external_ontology="FMA"}
property_value: UBPROP:0000012 "this class denotes a combination of fibrous PC + PC sac (itself a combination of cavity, epithelium and connective tissue). Many sources use the term 'pericardium' to denote either just the serous membrane (ZFA) or the epithelium (GO)" xsd:string {external_ontology="ZFA"}
property_value: UBPROP:0000012 "we follow FMA in dividing pericardium into pericardial sac and fibrous pericardium" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0002408
name: parietal serous pericardium
namespace: uberon
def: "Parietal serous membrane which is part of the pericardium and forms the outer layer of the pericardial sac." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: uberon_slim
synonym: "lamina parietalis (pericardii serosum)" EXACT []
synonym: "lamina parietalis pericardii" EXACT OMO:0003011 [FMA:9870, FMA:TA]
synonym: "parietal layer of serous pericardium" EXACT []
synonym: "parietal pericardium" EXACT [VHOG:0000537]
synonym: "pericardial sac" RELATED INCONSISTENT [DOI:10.5962/bhl.title.1013]
xref: EHDAA:3422
xref: EHDAA:5378
xref: EMAPA:19031
xref: FMA:9870
xref: MA:0000483
xref: NCIT:C94500
xref: SCTID:243956000
xref: UMLS:C0225969 {source="ncithesaurus:Parietal_Pericardium"}
xref: VHOG:0000537
xref: Wikipedia:Parietal_pericardium
is_a: UBERON:0022351 ! parietal serous membrane
intersection_of: UBERON:0022351 ! parietal serous membrane
intersection_of: part_of UBERON:0002357 ! serous pericardium
relationship: attaches_to UBERON:0006670 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! central tendon of diaphragm
relationship: part_of UBERON:0002357 ! serous pericardium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png" xsd:anyURI

[Term]
id: UBERON:0002409
name: pericardial fluid
namespace: uberon
def: "Transudate contained in the pericardial cavity.[FMA]." [FMA:9887, Wikipedia:Pericardial_fluid]
subset: uberon_slim
xref: BTO:0001016
xref: FMA:9887
xref: MA:0002530
xref: MESH:D000069236 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: Wikipedia:Pericardial_fluid
is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland
is_a: UBERON:0036217 ! coelomic fluid
intersection_of: UBERON:0000463 ! organism substance
intersection_of: produced_by UBERON:0002425 ! visceral serous pericardium
relationship: located_in UBERON:0001074 ! pericardial cavity
relationship: produced_by UBERON:0002425 ! visceral serous pericardium

[Term]
id: UBERON:0002410
name: autonomic nervous system
namespace: uberon
def: "The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands[GO]." [GO:0048483]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "ANS" RELATED OMO:0003000 []
synonym: "autonomic division of peripheral nervous system" EXACT [FMA:65553]
synonym: "autonomic part of peripheral nervous system" EXACT [FMA:65553]
synonym: "divisio autonomica systematis nervosi peripherici" EXACT [FMA:TA]
synonym: "divisio autonomica systematis nervosi peripherici" RELATED OMO:0003011 [Wikipedia:Autonomic_nervous_system]
synonym: "pars autonomica systematis nervosi peripherici" EXACT [FMA:TA]
synonym: "peripheral autonomic nervous system" EXACT [FMA:65553]
synonym: "visceral nervous system" EXACT []
xref: AAO:0000033
xref: BIRNLEX:1123
xref: BTO:0002507
xref: CALOHA:TS-2001
xref: EHDA:10095
xref: EHDAA2:0000158
xref: EHDAA:3767
xref: EMAPA:16984
xref: FMA:65553
xref: GAID:706
xref: IDOMAL:0002126 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: MA:0000219
xref: MESH:D001341
xref: NCIT:C12673
xref: neuronames:2054
xref: SCTID:362481007
xref: TAO:0001574
xref: UMLS:C0004388 {source="ncithesaurus:Autonomic_Nervous_System", source="BIRNLEX:1123"}
xref: UMLS:C1305381 {source="BIRNLEX:1123"}
xref: VHOG:0000396
xref: Wikipedia:Autonomic_nervous_system
xref: ZFA:0001574
is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision
relationship: contributes_to_morphology_of UBERON:0001016 ! nervous system
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0000010 {source="EMAPA", source="MA", source="NIFSTD", source="ZFA-modified-from-isa"} ! peripheral nervous system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI
property_value: UBPROP:0000001 "Nervous system including a portion of the central and peripheral systems and presiding over the control and coordination of the vegetative functions of the organism. It innervates smooth and cardiac muscles and glandular tissues and is responsible for many actions which are more or less automatic (e.g. secretion, vasoconstriction etc.). It consists of the sympathetic and parasympathetic nervous systems. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000396", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000001 "Part of the peripheral nervous system which regulates involuntary functions of the body and consists of the sympathetic and parasympathetic system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000033", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000003 "From comparative analyses of craniate brains, a morphotype of the brain in the earliest craniate stock can be constructed. In marked contrast to cephalochordates, the ancestral craniate morphotype had a plethora of unique features, which included a telencephalon with pallial and subpallial parts, paired olfactory bulbs with substantial projections to most or all of the telencephalic pallium, paired lateral eyes and ears, a lateral line system for both electroreception and mechanoreception, spinal cord dorsal root ganglia, and an autonomic nervous system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000396", ontology="VHOG", source="DOI:10.1002/1097-0185(20000615)261:3<111::AID-AR6>3.0.CO;2-F Butler AB, Chordate evolution and the origin of craniates: An old brain in a new head. AnaT Rec (New Anat) (2000)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "FMA splits this into peripheral and nervous parts; GO has ANS directly under NS; PNS is a sib" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0002411
name: clitoris
namespace: uberon
def: "The small, erectile body located at the anterior end of the vulva." [ISBN:0-683-40008-8, MP:0003127]
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
xref: BTO:0002020
xref: EHDAA2:0000255
xref: EHDAA:9360
xref: EMAPA:30819
xref: FMA:9909
xref: GAID:385
xref: galen:Clitoris
xref: MA:0000382
xref: MESH:D002987
xref: NCIT:C12308
xref: SCTID:181442003
xref: UMLS:C0008984 {source="ncithesaurus:Clitoris"}
xref: VHOG:0000700
xref: Wikipedia:Clitoris
is_a: UBERON:0000062 {source="Wikipedia"} ! organ
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
relationship: contributes_to_morphology_of UBERON:0005056 ! external female genitalia
relationship: develops_from UBERON:0005876 {source="EHDAA2", source="Wikipedia"} ! undifferentiated genital tubercle
relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia
relationship: part_of UBERON:0000997 {source="MA"} ! mammalian vulva
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/cf/Clitoris_anatomy_labeled-en.svg" xsd:anyURI
property_value: UBPROP:0000007 "clitoral" xsd:string

[Term]
id: UBERON:0002412
name: vertebra
namespace: uberon
def: "The ossified form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, http://orcid.org/0000-0002-6601-2165, VSAO:0000184]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "vertebra bone" EXACT []
synonym: "vertebrae" EXACT OMO:0003004 [PHENOSCAPE:ad]
xref: AAO:0000691
xref: BTO:0006196 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: CALOHA:TS-2352
xref: EFO:0001371
xref: EMAPA:32740
xref: FMA:9914
xref: galen:Vertebra
xref: MA:0000309
xref: NCIT:C12933
xref: SCTID:181817002
xref: TAO:0001189
xref: UMLS:C0549207 {source="ncithesaurus:Vertebra"}
xref: Wikipedia:Vertebra
xref: XAO:0004019
xref: ZFA:0001189
is_a: UBERON:0002513 ! endochondral bone
is_a: UBERON:0008001 {source="FMA"} ! irregular bone
is_a: UBERON:0010913 ! vertebral element
intersection_of: UBERON:0010913 ! vertebral element
intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue
relationship: develops_from UBERON:0011094 ! vertebra cartilage element
relationship: part_of UBERON:0001130 ! vertebral column
property_value: editor_note "Consider changing name to make distinction from inferred superclass 'vertebral element' clear" xsd:string
property_value: editor_note "we follow FMA in making this an irregular bone - however vertebra have 'epiphyses' which are currently classified as belonging to long bones" xsd:string
property_value: RO:0002161 NCBITaxon:7901 {source="Wikipedia"}
property_value: UBPROP:0000001 "Endochondral bone that forms around the notochord and is part of the vertebral column.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001189", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Main component of the vertebral column. It consists of two essential parts, a dorsal neural arch and a ventral centrum.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000691", ontology="AAO", source="AAO:Pugener_and_Maglia_2008"}

[Term]
id: UBERON:0002413
name: cervical vertebra
namespace: uberon
def: "A vertebra that is located in the cervical region of the vertebral column." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "cervical vertebrae" EXACT OMO:0003004 []
synonym: "vertebrae cervicales" RELATED OMO:0003011 [Wikipedia:Cervical_vertebrae]
xref: EMAPA:17674
xref: FMA:9915
xref: GAID:235
xref: galen:CervicalVertebra
xref: MA:0000311
xref: MESH:D002574
xref: NCIT:C12693
xref: SCTID:181820005
xref: Wikipedia:Cervical_vertebrae
xref: XAO:0003076
is_a: UBERON:0003458 ! neck bone
is_a: UBERON:0004247 ! bone of dorsum
is_a: UBERON:0004451 {is_inferred="true"} ! trunk or cervical vertebra
is_a: UBERON:0015007 ! cervical vertebra endochondral element
intersection_of: UBERON:0015007 ! cervical vertebra endochondral element
intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue
relationship: develops_from UBERON:0013505 ! cervical vertebra cartilage element
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f8/Illu_vertebral_column.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "In some species, some parts of the skull may be composed of vertebra-like elements, e.g. the occipital bone in humans is composed of four vertebra-like segments. In many vertebrate species, cervical vertebrae are variable in number; however, almost all mammals have seven (including those with very short necks relative to body size, such as elephants or whales, and those with very long necks, such as giraffes). The few exceptions include the manatee and the sloths, of which the two-toed sloth has six cervical vertebrae and the three-toed sloth has up to nine cervical vertebrae. In many species, though not in mammals, the cervical vertebrae bear ribs. In many other groups, such as lizards and saurischian dinosaurs, the cervical ribs are large; in birds they are small and completely fused to the vertebrae. The transverse processes of mammals are homologous to the cervical ribs of other amniotes. Thoracic vertebrae in all species are defined as those vertebrae which also carry a pair of ribs, and lie caudal to the cervical vertebrae. In humans, cervical vertebrae are the smallest of the true vertebrae, and can be readily distinguished from those of the thoracic or lumbar regions by the presence of a foramen (hole) in each transverse process, through which passes the vertebral artery." xsd:string

[Term]
id: UBERON:0002415
name: tail
namespace: uberon
def: "An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail." [AEO:0000109, Wikipedia:Tail]
subset: efo_slim
subset: grouping_class
subset: pheno_slim
subset: uberon_slim
synonym: "caudal subdivision" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: AEO:0000109
xref: BILA:0000117
xref: BTO:0001348
xref: EFO:0000963
xref: EHDAA:9198
xref: GAID:1245
xref: MAT:0000094
xref: MESH:D013623
xref: MIAA:0000094
xref: WBbt:0005741
xref: Wikipedia:Tail
is_a: UBERON:0011676 ! subdivision of organism along main body axis
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
relationship: part_of UBERON:0000154 ! posterior region of body
property_value: editor_note "Note we also have a subclass post-anal tail, for the chordate specific structure. currently defined very generally, inclusive of caudal fin" xsd:string
property_value: RO:0002161 NCBITaxon:9606

[Term]
id: UBERON:0002416
name: integumental system
namespace: uberon
alt_id: UBERON:0007029
def: "Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle." [CARO:0002001, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/29]
subset: efo_slim
subset: grouping_class
subset: human_reference_atlas
subset: pheno_slim
synonym: "body surface" RELATED []
synonym: "dermal system" RELATED [MIAA:0000033]
synonym: "external covering of organism" RELATED []
synonym: "integumentary system" EXACT [FMA:72979]
synonym: "integumentum commune" RELATED OMO:0003011 [Wikipedia:Integumentary_system]
synonym: "organism surface" RELATED [EHDAA2:0003154]
synonym: "surface" RELATED [BILA:0000118]
xref: AEO:0000154
xref: BILA:0000118
xref: CALOHA:TS-1299
xref: CARO:0002001
xref: EFO:0000807
xref: EHDAA2:0000836
xref: EHDAA2_RETIRED:0003154
xref: EHDAA:6520
xref: EMAPA:17524
xref: EV:0100151
xref: FBbt:00004969 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:72979
xref: galen:Surface
xref: HAO:0000421
xref: MA:0000014
xref: MAT:0000033
xref: MESH:D034582
xref: MIAA:0000033
xref: NCIT:C12907
xref: SCTID:361692004
xref: TADS:0000108
xref: UMLS:C0037267 {source="ncithesaurus:Integumentary_System"}
xref: VHOG:0000403
xref: Wikipedia:Integumentary_system
xref: XAO:0000176
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000467 ! anatomical system
disjoint_from: UBERON:0002423 ! hepatobiliary system
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: bounding_layer_of UBERON:0000468 ! multicellular organism
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: has_part UBERON:0007376 ! outer epithelium
relationship: surrounded_by UBERON:0013514 ! space surrounding organism
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/tfhayamizu
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "(...) the integument of many tetrapods is reinforced by a morphologically and structurally diverse assemblage of skeletal elements. These elements are widely understood to be derivatives of the once all-encompassing dermal skeleton of stem-gnathostomes (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000403", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2008.01043.x Vickaryous MK, Sire JY, The integumentary skeleton of tetrapods: origin, evolution, and development. J Anat (2009)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002417
name: abdominal segment of trunk
namespace: uberon
def: "The abdominal segment of the torso." [Wikipedia:Lumbar]
synonym: "abdomen/pelvis/perineum" RELATED [MA:0000021]
synonym: "lower body" RELATED [MA:0000021]
synonym: "lower trunk" RELATED [FMA:259211]
synonym: "lumbar region" RELATED [https://orcid.org/0000-0002-6601-2165]
xref: EMAPA:35104
xref: FMA:259211
xref: MA:0000021
xref: SCTID:362875007
xref: Wikipedia:Lumbar
is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk
is_a: UBERON:0011676 ! subdivision of organism along main body axis

[Term]
id: UBERON:0002418
name: cartilage tissue
namespace: uberon
def: "Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/37, https://sourceforge.net/p/obo/vertebrate-skeletal-anatomy-vsao-term-requests/5, PSPUB:0000170, VSAO:0000040]
comment: Previous: "A portion of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate[GO]. Regular connective tissue, which consists of chondrocytes and related cells, the intercellular matrix of which is chondrified. Examples: hyaline cartilage, fibrocartilage, elastic cartilage[FMA]. an avascular supporting and articular skeletal tissue. It also functions as the primary endoskeletal support in vertebrate embryos. Cartilage is deposited by and is composed of chondroblasts and chondrocytes separated by an extracellular matrix, which may or may not mineralize depending on cartilage type, age, or taxon[Hall and Witten]." See also FMA:71500 Set of cartilages, FMA:55107 Cartilage organ, FMA:12264 Articular cartilage. // elements made from cartilage, cartilage-like, or chondroid tissues evolved in invertebrates[H&W]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cartilage" RELATED []
synonym: "cartilage tissue" EXACT [FMA:37377]
synonym: "cartilages" RELATED [VHOG:0001207]
synonym: "cartilaginous tissue" EXACT []
synonym: "chondrogenic tissue" EXACT [VSAO:0000040]
synonym: "portion of cartilage tissue" RELATED [FMA:37377]
xref: AAO:0000060
xref: AEO:0000087
xref: BTO:0000206
xref: EFO:0000949
xref: EHDAA2:0003087
xref: EMAPA:32730
xref: EV:0100141
xref: FMA:37377
xref: GAID:99
xref: galen:Cartilage
xref: MA:0000104
xref: MAT:0000189
xref: MESH:D002356
xref: MIAA:0000189
xref: NCIT:C12373
xref: NCIT:C32268
xref: SCTID:309312004
xref: TAO:0001501
xref: UMLS:C0007301 {source="ncithesaurus:Cartilage"}
xref: VHOG:0001207
xref: VSAO:0000040
xref: Wikipedia:Cartilage
xref: XAO:0000170
xref: ZFA:0005622
is_a: UBERON:0004755 ! skeletal tissue
disjoint_from: UBERON:0002481 {source="https://github.com/obophenotype/uberon/issues/117"} ! bone tissue
relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system
relationship: has_part CHEBI:18085 ! glycosaminoglycan
relationship: has_part CL:0000138 ! chondrocyte
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg" xsd:anyURI
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly
property_value: UBPROP:0000001 "A type of dense connective tissue. It is composed of cells called chondrocytes which are dispersed in a firm gel-like ground substance, called the matrix. Cartilage is avascular (contains no blood vessels) and nutrients are diffused through the matrix. Cartilage is found in the joints, the rib cage, the ear, the nose, in the throat and between intervertebral disks. It makes up virtually the entire skeleton in chondrichthyes.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000060", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000001 "Portion of tissue which is connective tissue composed of collagen and/or elastin fibers and chondrocytes. Cartilage is avascular and provides both skeletal functions and a framework upon which bone is deposited.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001501", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000040", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"}
property_value: UBPROP:0000002 "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000060", ontology="AAO"}
property_value: UBPROP:0000003 "Phylogenetic analysis suggests that cartilage arose independently in cnidarians, hemichordates, vertebrates, arthropods, annelids, brachiopods, and molluscs - or a common ancestor of brachiopods and molluscs (...). Analyses of cartilage as a tissue and of the development of invertebrate cartilages are consistent with homology between invertebrate and vertebrate cartilage. From the discussion above, it will be clear that understanding genetic changes underlying cartilage evolution is key to determining whether the multiple origins of cartilage represent parallel evolution.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001207", ontology="VHOG", source="DOI:10.1111/j.1525-142X.2011.00520.x Hall BK, Parallelism, deep homology, and evo-devo. Evolution and Development (2012)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002419
name: skin gland
namespace: uberon
def: "A gland that is part of a skin of body [Automatically generated definition]." [OBOL:automatic]
subset: organ_slim
synonym: "glandulae cutis" EXACT OMO:0003011 [FMA:71878, FMA:TA]
synonym: "set of skin glands" RELATED [FMA:71878]
synonym: "skin glands" RELATED OMO:0003004 []
synonym: "skin glands set" RELATED OMO:0003004 []
xref: EMAPA:35774
xref: FMA:71878
xref: MA:0000146
xref: SCTID:110485007
is_a: UBERON:0003297 ! gland of integumental system
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0006003 ! integumentary adnexa
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0002097 ! skin of body
relationship: part_of UBERON:0002097 ! skin of body
property_value: editor_note "check FMA, use plural for now as general class not there" xsd:string

[Term]
id: UBERON:0002423
name: hepatobiliary system
namespace: uberon
def: "The part of the digestive system that contains the liver and the biliary system." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "hepaticobiliary system" EXACT [GO:0061008]
synonym: "liver and biliary system" EXACT []
synonym: "liver/biliary system" RELATED []
xref: AAO:0011056
xref: CALOHA:TS-1308
xref: EFO:0000800
xref: EHDAA2:0000998
xref: EHDAA:2189
xref: EMAPA:16840
xref: EV:0100088
xref: MA:0000324
xref: MAT:0000024
xref: MIAA:0000024
xref: NCIT:C43612
xref: TAO:0000036
xref: UMLS:C1711359 {source="ncithesaurus:Hepatobiliary_System"}
xref: VHOG:0000294
xref: Wikipedia:Hepatobiliary_system
xref: XAO:0000132
xref: ZFA:0000036
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0011216 ! organ system subdivision
disjoint_from: UBERON:0004456 ! entire sense organ system
disjoint_from: UBERON:8450002 ! excretory system
relationship: capable_of GO:0061007 ! hepaticobiliary system process
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: has_part UBERON:0002107 ! liver
relationship: has_part UBERON:0002294 ! biliary system
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0001007 ! digestive system
property_value: UBPROP:0000001 "System responsible for the production and movement of bile[ZFIN:curator]." xsd:string {source="ZFIN:curator"}
property_value: UBPROP:0000009 "The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. The parts are: liver, bile duct, gall bladder and hepatic duct [GO:0061008]" xsd:string

[Term]
id: UBERON:0002424
name: oral epithelium
namespace: uberon
def: "An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues." [https://orcid.org/0000-0002-6601-2165]
subset: vertebrate_core
synonym: "epithelium of mucosa of mouth" EXACT [FMA:265152]
synonym: "epithelium of oral mucosa" EXACT [FMA:265152]
xref: AAO:0010357
xref: BTO:0001775
xref: CALOHA:TS-0715
xref: EHDAA2:0001325
xref: EHDAA:2187
xref: EMAPA:16839
xref: EMAPA:26942
xref: FMA:265152
xref: MA:0000344
xref: NCIT:C49595
xref: TAO:0000816
xref: UMLS:C1709332 {source="ncithesaurus:Oral_Cavity_Epithelium"}
xref: VHOG:0000187
xref: XAO:0003201
xref: ZFA:0000816
is_a: UBERON:0003350 ! epithelium of mucosa
is_a: UBERON:0003929 ! digestive tract epithelium
is_a: UBERON:0006915 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! stratified squamous epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0003729 ! mouth mucosa
relationship: adjacent_to UBERON:0000167 {source="AAO-modified"} ! oral cavity
relationship: part_of UBERON:0003729 ! mouth mucosa
property_value: editor_note "consider including separate class for developmental structure (adult human is stratified; in EHDAA2 is unilaminar)" xsd:string
property_value: UBPROP:0000001 "The epithelium that lines the oral cavity. The oral epithelium epithelial cells with many short microvilli as well as mucous cells, rodlet cells and taste buds[ZFIN:ZDB-PUB-060921-12, ZFIN:ZDB-PUB-091204-24]." xsd:string {source="ZFA:0000816"}
property_value: UBPROP:0000011 "the avian oral epithelium has the developmental capacity to initiate tooth developmental programs with underlying grafts of non-avian oral ectomesenchyme" xsd:string {source="PMID:16488870"}

[Term]
id: UBERON:0002425
name: visceral serous pericardium
namespace: uberon
def: "Visceral serous membrane which is continuous with the parietal serous pericardium and is attached to the myocardium[FMA]." [Wikipedia:Visceral_pericardium]
subset: pheno_slim
subset: uberon_slim
synonym: "epicardium" RELATED [MA:0000484]
synonym: "lamina visceralis pericardii serosi" EXACT OMO:0003011 [Wikipedia:Epicardium]
synonym: "pericardium visceral mesothelium" RELATED [EMAPA:16589]
synonym: "serous visceral pericardium" EXACT []
synonym: "visceral lamina of serous pericardium" EXACT []
synonym: "visceral layer of serous pericardium" EXACT []
synonym: "visceral pericardium" EXACT [VHOG:0000538]
xref: EMAPA:16589
xref: EMAPA:19032
xref: FMA:84882
xref: MA:0000484
xref: SCTID:243955001
xref: VHOG:0000538
xref: Wikipedia:Visceral_pericardium
is_a: UBERON:0022350 ! visceral serous membrane
intersection_of: UBERON:0022350 ! visceral serous membrane
intersection_of: part_of UBERON:0002357 ! serous pericardium
relationship: attaches_to UBERON:0002349 {source="FMA"} ! myocardium
relationship: contributes_to_morphology_of UBERON:0002407 ! pericardium
relationship: has_part UBERON:0002348 {source="cjm"} ! epicardium
relationship: part_of UBERON:0002357 ! serous pericardium

[Term]
id: UBERON:0002443
name: choroidal blood vessel
namespace: uberon
def: "A blood vessel that is part of a choroid [Automatically generated definition]." [OBOL:automatic]
comment: cannot find singular in FMA, using Set class
subset: pheno_slim
synonym: "blood vessel of choroid" EXACT [OBOL:automatic]
synonym: "blood vessel of choroid coat" EXACT [OBOL:automatic]
synonym: "blood vessel of choroidea" EXACT [OBOL:automatic]
synonym: "blood vessel of posterior uvea" EXACT [OBOL:automatic]
synonym: "choroid blood vessel" EXACT [OBOL:automatic]
synonym: "choroid blood vessels" EXACT []
synonym: "choroid blood vessels set" EXACT []
synonym: "choroid coat blood vessel" EXACT [OBOL:automatic]
synonym: "choroidea blood vessel" EXACT [OBOL:automatic]
synonym: "posterior uvea blood vessel" EXACT [OBOL:automatic]
synonym: "set of choroid blood vessels" RELATED [FMA:76550]
synonym: "vasa sanguinea choroideae" EXACT OMO:0003011 [FMA:76550, FMA:TA]
xref: EMAPA:17828
xref: FMA:76550
xref: MA:0001237
is_a: UBERON:0003496 ! head blood vessel
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0001776 ! optic choroid
relationship: part_of UBERON:0001776 ! optic choroid

[Term]
id: UBERON:0002450
name: decidua
namespace: uberon
def: "The maternal uterine-derived portion of the placenta." [MP:0004256, PMID:11433360]
subset: pheno_slim
subset: uberon_slim
synonym: "decidous membrane" EXACT [FMA:85538]
synonym: "decidua basalis" RELATED []
synonym: "endometrium" RELATED []
synonym: "extraembryonic part of placenta" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "extraembryonic placenta" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "maternal decidual layer" RELATED [MP:0004256]
synonym: "maternal part of placenta" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "maternal placenta" RELATED [EMAPA:35269, GOC:dph]
synonym: "placenta maternal decidual layer" RELATED []
synonym: "uterine decidua" RELATED [BTO:0001360]
xref: BTO:0001360
xref: CALOHA:TS-0193
xref: EMAPA:35269
xref: FMA:85538
xref: GAID:378
xref: MA:0001722
xref: MAT:0000290
xref: MESH:D003656
xref: MIAA:0000290
xref: NCIT:C32425
xref: SCTID:362842004
xref: UMLS:C0011106 {source="ncithesaurus:Decidua"}
xref: Wikipedia:Decidua
is_a: UBERON:0000478 {source="FMA"} ! extraembryonic structure
relationship: contributes_to_morphology_of UBERON:0001987 ! placenta
relationship: develops_from UBERON:0000459 ! uterine wall
relationship: part_of UBERON:0001987 {component="maternal", source="MA"} ! placenta
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray33.png" xsd:anyURI
property_value: editor_note "TODO - check mp syn" xsd:string
property_value: UBPROP:0000011 "formed under the influence of progesterone and forms highly-characteristic cells. [Wikipedia:Decidua]" xsd:string

[Term]
id: UBERON:0002451
name: endometrial gland
namespace: uberon
def: "The mucous secreting gland associated with the mucuous membrane lining the uterus." [Wikipedia:Uterine_glands]
subset: human_reference_atlas
subset: organ_slim
subset: pheno_slim
subset: uberon_slim
synonym: "endometrial gland" EXACT [BTO:0003433]
synonym: "endometrial mucuous gland" EXACT []
synonym: "endometrium gland" EXACT []
synonym: "glandulae uterinae" EXACT OMO:0003011 [FMA:71647, FMA:TA]
synonym: "glandulae uterinae" RELATED OMO:0003011 [Wikipedia:Uterine_glands]
synonym: "uterine gland" EXACT []
xref: BTO:0003433
xref: BTO:0004518
xref: EMAPA:29919
xref: MA:0001726
xref: NCIT:C33842
xref: SCTID:361377009
xref: UMLS:C1183035 {source="ncithesaurus:Uterine_Gland"}
xref: Wikipedia:Uterine_glands
is_a: UBERON:0000414 {source="MP"} ! mucous gland
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005179 ! pelvic region element
is_a: UBERON:0005398 ! female reproductive gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0001295 ! endometrium
relationship: has_quality PATO:0002299 {source="Wikipedia:Tubular_gland"} ! tubular
relationship: part_of UBERON:0012276 ! endometrium glandular epithelium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/28/Gray1169.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000010 "simple or branched tubular" xsd:string
property_value: UBPROP:0000202 FMA:71647

[Term]
id: UBERON:0002457
name: intersomitic artery
namespace: uberon
alt_id: UBERON:0006001
def: "The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries." [MP:0010662]
subset: pheno_slim
subset: vertebrate_core
synonym: "intersegmental arteries" RELATED OMO:0003004 [ZFA:0001061]
synonym: "intersegmental artery" EXACT [ZFA:0001061]
xref: EHDAA2:0000882
xref: EHDAA:4340
xref: EMAPA:17616
xref: MA:0001985
xref: SCTID:360401001
xref: TAO:0001061
xref: VHOG:0000225
xref: XAO:0004165
xref: ZFA:0001061
is_a: UBERON:0001637 ! artery
is_a: UBERON:0014907 ! intersomitic vessel
property_value: UBPROP:0000001 "Arteries that connect the dorsal aorta and the dorsal longitudinal anastomotic vessel. They run along the vertical myotomal boundaries. At early stages these vessels don't have venous or arteriproperty_value external_definitionmarkers. They form from the primary sprouts from the dorsal aorta[ZFA:0001061]." xsd:string {source="ZFA:0001061"}
property_value: UBPROP:0000003 "Few changes of evolutionary significance occur in the branching pattern of the dorsal aorta. All vertebrates have (...) paired intersegmental arteries to the trunk, tail, and paired appendages.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000225", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.612", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002458
name: spinal artery
namespace: uberon
def: "Arteries that supply the spinal cord." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Spinal_artery]
subset: uberon_slim
subset: vertebrate_core
synonym: "spinal arteries" EXACT OMO:0003004 [ZFA:0000682]
xref: EHDAA2:0001890
xref: EHDAA:4355
xref: EMAPA:18241
xref: MA:0002043
xref: NCIT:C33587
xref: SCTID:244228006
xref: TAO:0000682
xref: UMLS:C0447043 {source="ncithesaurus:Spinal_Artery"}
xref: Wikipedia:Spinal_artery
xref: ZFA:0000682
is_a: UBERON:0004573 ! systemic artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0002240 ! spinal cord
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0002240 ! spinal cord

[Term]
id: UBERON:0002460
name: vesical vein
namespace: uberon
def: "A tributary of the iliac vein that drains the urinary bladder." [UBERON:cjm, Wikipedia:Vesical_veins]
subset: human_reference_atlas
subset: uberon_slim
synonym: "venae vesicales" EXACT OMO:0003011 [FMA:70911, FMA:TA]
synonym: "vesical veins" EXACT OMO:0003004 []
synonym: "vesical veins set" EXACT []
xref: EMAPA:37205 {source="MA:th"}
xref: MA:0002263
xref: SCTID:12683000
xref: Wikipedia:Vesical_veins
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0001255 ! urinary bladder
relationship: drains UBERON:0001255 ! urinary bladder
relationship: part_of RO:0002577 ! system
relationship: tributary_of UBERON:0001317 ! internal iliac vein
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray585.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000202 FMA:70911

[Term]
id: UBERON:0002466
name: intestine secretion
namespace: uberon
def: "Clear to pale yellow watery secretions from the glands lining the small intestine walls. Secretion is stimulated by the mechanical pressure of partly digested food in the intestine." [Wikipedia:Succus_entericus]
subset: pheno_slim
subset: uberon_slim
synonym: "intestinal juice" RELATED [BTO:0000644]
synonym: "intestinal secretion" EXACT [FMA:62974]
synonym: "succus entericus" EXACT [Wikipedia:Succus_entericus]
xref: BTO:0000644
xref: FMA:62974
xref: GAID:1162
xref: MA:0002515
xref: MESH:D007419
xref: NCIT:C32875
xref: UMLS:C0021849 {source="ncithesaurus:Intestinal_Secretion"}
xref: Wikipedia:Succus_entericus
is_a: UBERON:0000456 ! secretion of exocrine gland
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: produced_by UBERON:0000160 ! intestine
relationship: produced_by UBERON:0000160 ! intestine

[Term]
id: UBERON:0002469
name: esophagus mucosa
namespace: uberon
alt_id: UBERON:0003345
def: "A mucosa that is part of a esophagus [Automatically generated definition]." [OBOL:automatic]
synonym: "esophageal mucosa" EXACT []
synonym: "esophageal mucous membrane" EXACT []
synonym: "esophagus mucosa" EXACT [FMA:62996]
synonym: "esophagus mucous membrane" EXACT [OBOL:automatic]
synonym: "lamina muscularis mucosae oesophageae" EXACT OMO:0003011 [FMA:62996, FMA:TA]
synonym: "mucosa of esophagus" EXACT [OBOL:automatic]
synonym: "mucosa of oesophagus" EXACT [OBOL:automatic]
synonym: "mucous membrane of esophagus" EXACT []
synonym: "mucous membrane of oesophagus" EXACT [FMA:62996]
synonym: "muscularis mucosae of oesophagus" RELATED INCONSISTENT [FMA:62996]
synonym: "oesophageal mucosa" EXACT [FMA:62996]
synonym: "oesophagus mucosa" EXACT []
synonym: "oesophagus mucous membrane" EXACT [OBOL:automatic]
synonym: "tunica mucosa esophagi" EXACT []
synonym: "tunica mucosa oesophageae" EXACT OMO:0003011 [FMA:62996, FMA:TA]
synonym: "tunica mucosa oesophagi" EXACT []
synonym: "tunica mucosa oesophagi" RELATED [BTO:0002859]
xref: BTO:0002859
xref: EMAPA:26981
xref: FMA:62996
xref: MA:0002680
xref: MESH:D000071041 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C32538
xref: SCTID:362127004
xref: UMLS:C0227176 {source="ncithesaurus:Esophageal_Mucosa"}
is_a: UBERON:0000344 ! mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001096 ! wall of esophagus

[Term]
id: UBERON:0002481
name: bone tissue
namespace: uberon
def: "Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000047]
subset: pheno_slim
subset: uberon_slim
synonym: "bone" RELATED [MESH:A02.835.232]
synonym: "calcium tissue" EXACT []
synonym: "mineralized bone tissue" NARROW [XAO:0004040]
synonym: "osseous tissue" EXACT []
synonym: "osteogenic tissue" EXACT [VSAO:curator]
synonym: "portion of bone tissue" RELATED [FMA:224804]
xref: CALOHA:TS-2011
xref: EMAPA:35179
xref: FMA:224804
xref: galen:BoneTissue
xref: MA:0002780
xref: MESH:D001842
xref: NCIT:C13076
xref: UMLS:C0391978 {source="ncithesaurus:Bone_Tissue"}
xref: VSAO:0000047
xref: Wikipedia:Bone_tissue
xref: XAO:0004040
xref: ZFA:0005621
is_a: UBERON:0004755 {source="VSAO"} ! skeletal tissue
disjoint_from: UBERON:0005090 ! muscle structure
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0001474 ! bone element
property_value: editor_note "see https://github.com/obophenotype/uberon/issues/27" xsd:string
property_value: UBPROP:0000001 "Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000047", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"}

[Term]
id: UBERON:0002506
name: iris epithelium
namespace: uberon
def: "An epithelium that is part of a iris [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
subset: pheno_slim
synonym: "epithelial tissue of iris" EXACT [OBOL:automatic]
synonym: "epithelium of iris" EXACT [OBOL:automatic]
synonym: "epithelium pigmentosum (iris)" EXACT [FMA:58517]
synonym: "epithelium pigmentosum iridis" EXACT OMO:0003011 [FMA:58517, FMA:TA]
synonym: "iris epithelial tissue" EXACT [OBOL:automatic]
synonym: "iris epithelium" EXACT [FMA:58517]
synonym: "iris pigmented epithelium" RELATED [MA:0002826]
synonym: "pigmented epithelium of iris" EXACT [FMA:58517]
xref: EMAPA:35447
xref: FMA:58517
xref: MA:0002826
is_a: UBERON:0000488 {source="FMA"} ! atypical epithelium
is_a: UBERON:0015808 ! eye epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001769 ! iris
relationship: contributes_to_morphology_of UBERON:0001769 ! iris
relationship: has_part GO:0048770 {source="MP"} ! pigment granule
relationship: part_of UBERON:0001769 {source="MA"} ! iris
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002511
name: trabecula carnea
namespace: uberon
def: "The supporting bundles of muscular fibers lining the walls of the ventricles of the heart." [MGI:monikat, MP:0004067]
subset: pheno_slim
synonym: "cardiac trabecula" RELATED [GO:0060347]
synonym: "columnae carneae" RELATED OMO:0003011 [Wikipedia:Trabeculae_carneae]
synonym: "heart trabecula" RELATED [GO:0060347]
synonym: "trabecula of heart" RELATED []
synonym: "trabeculae carneae" RELATED OMO:0003004 []
synonym: "trabeculae carneae cordis" RELATED OMO:0003011 [Wikipedia:Trabeculae_carneae]
synonym: "ventricle trabecula carnea" EXACT [MA:0002831]
synonym: "ventricular trabecula" RELATED [MA:0002831]
xref: EMAPA:18626
xref: FMA:7269
xref: MA:0002831
xref: SCTID:118755002
xref: Wikipedia:Trabeculae_carneae
is_a: UBERON:0000440 ! trabecula
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: composed_primarily_of UBERON:0001133 ! cardiac muscle tissue
relationship: part_of UBERON:0002082 {source="WP"} ! cardiac ventricle
property_value: UBPROP:0000009 "The purpose of the trabeculae carneae is most likely to prevent suction that would occur with a flat surfaced membrane and thus impair the heart's ability to pump efficiently. The trabeculae carneae also serve a similar function to papillary muscles in that their contraction pulls on the chordae tendineae, preventing inversion of the mitral (bicuspid) and tricuspid valves, that is, their bulging towards the atrial chambers, which would lead to subsequent leakage of the blood into the atria. So by the action of papillary muscles on the atrioventricular valves, backflow of the blood from the ventricles into the atria is prevented" xsd:string {source="WP"}
property_value: UBPROP:0000012 "Note that WP states they are ventricular, but MP has classes for atrial ventricular carnea." xsd:string {external_ontology="MP"}

[Term]
id: UBERON:0002513
name: endochondral bone
namespace: uberon
def: "Replacement bone that forms within cartilage." [GO:0001958, GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/54, VSAO:0000145]
subset: uberon_slim
subset: vertebrate_core
synonym: "cartilaginous bone" RELATED [BTO:0002157]
synonym: "endochondral bones" RELATED OMO:0003004 [ZFA:0001591]
synonym: "ossified chondrogenic bone" EXACT [VSAO:0000145]
xref: AAO:0010776
xref: AEO:0000083
xref: BTO:0002157
xref: EHDAA2:0003083
xref: FMA:24321
xref: TAO:0001591
xref: VSAO:0000145
xref: XAO:0004018
xref: ZFA:0001591
is_a: UBERON:0001474 ! bone element
is_a: UBERON:0010363 {source="VSAO"} ! endochondral element
intersection_of: UBERON:0001474 ! bone element
intersection_of: develops_from UBERON:0005863 ! cartilaginous condensation
relationship: developmentally_replaces UBERON:0002418 ! cartilage tissue
relationship: develops_from UBERON:0007844 {source="VSAO"} ! cartilage element
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg" xsd:anyURI
property_value: editor_note "placement in this class to be inferred" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern" xsd:anyURI
property_value: UBPROP:0000001 "Replacement bone that forms within cartilage.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000145", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"}
property_value: UBPROP:0000012 "some structures, e.g. in ZFA are both intramembrane and endochondral" xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0002514
name: intramembranous bone
namespace: uberon
def: "Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]." [GO:0001957, https://github.com/obophenotype/uberon/issues/267, Wikipedia:Intramembranous_ossification]
synonym: "intramembranous bones" RELATED OMO:0003004 [ZFA:0001635]
synonym: "membrane bone" RELATED [AEO:0000085]
xref: EMAPA:36615
xref: TAO:0001644
xref: Wikipedia:Intramembranous_ossification
xref: ZFA:0001635
is_a: UBERON:0001474 {source="VSAO"} ! bone element
relationship: develops_from UBERON:0003104 ! mesenchyme
relationship: output_of GO:0001957 ! intramembranous ossification
property_value: UBPROP:0000001 "Bone that forms directly within mesenchyme, and does not replace other tissues.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001644", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000005 "[In TAO], This term was made obsolete because it is considered a synonym of membrane bone (VSAO:0000023).[TAO]" xsd:string {date_retrieved="2012-09-06", external_class="TAO:0001644", ontology="TAO", source="Curator"}

[Term]
id: UBERON:0002517
name: basicranium
namespace: uberon
def: "The base of skull is the most inferior area of the skull, composed of the endocranium and lower parts of the skull roof." [Wikipedia:Base_of_skull]
comment: The skull base is formed from a series of cartilages either side of, and rostral to, the notochord, whose tip lies just caudal to the pituitary gland. It is closely associated with the sensory capsules, which partially or completely sur- round the olfactory epithelium, the eye, and the inner ear[PMID:11523816]
subset: pheno_slim
subset: uberon_slim
synonym: "base of cranium" EXACT []
synonym: "base of skull" EXACT [FMA:52801]
synonym: "basis cranii" EXACT OMO:0003011 [FMA:52801, FMA:TA, Wikipedia:Base_of_skull]
synonym: "cranial base" EXACT [FMA:52801, MA:0002840]
xref: FMA:52801
xref: MA:0002840
xref: MESH:D019291
xref: MFMO:0000044
xref: NCIT:C12493
xref: SCTID:181890004
xref: UMLS:C0149543 {source="ncithesaurus:Base_of_the_Skull"}
xref: Wikipedia:Base_of_skull
is_a: UBERON:0000075 ! subdivision of skeletal system
relationship: contributes_to_morphology_of UBERON:0003128 ! cranium
relationship: part_of UBERON:0001703 ! neurocranium
relationship: part_of UBERON:0002241 ! chondrocranium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray193.png" xsd:anyURI
property_value: UBPROP:0000007 "basicranial" xsd:string

[Term]
id: UBERON:0002521
name: elastic tissue
namespace: uberon
def: "Connective tissue composed of elastic fibers." [http://orcid.org/0000-0002-6601-2165]
subset: uberon_slim
synonym: "elastic connective tissue" EXACT []
synonym: "elastic fiber" NARROW []
synonym: "textus connectivus elasticus" EXACT OMO:0003011 []
xref: FMA:20113
xref: GAID:926
xref: MA:0002853
xref: MESH:D004547
xref: NCIT:C32495
xref: SCTID:27197004
xref: Wikipedia:Elastic_fiber
is_a: UBERON:0002384 ! connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: composed_primarily_of GO:0071953 ! elastic fiber
relationship: composed_primarily_of GO:0071953 ! elastic fiber
relationship: has_quality PATO:0001171 ! elastic
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/cb/Gray377.png" xsd:anyURI

[Term]
id: UBERON:0002522
name: tunica media
namespace: uberon
def: "The middle layer of an artery or vein. [WP,unvetted]." [Wikipedia:Tunica_media]
comment: May be composed of smooth muscle and elastic tissue
subset: uberon_slim
synonym: "tunica media vasorum" RELATED OMO:0003011 [BTO:0002011, Wikipedia:Tunica_media]
xref: BTO:0002011
xref: EMAPA:36298
xref: FMA:55590
xref: GAID:170
xref: MA:0002855
xref: MESH:D017540
xref: NCIT:C33821
xref: SCTID:61695000
xref: UMLS:C0162867 {source="ncithesaurus:Tunica_Media"}
xref: Wikipedia:Tunica_media
is_a: UBERON:0004797 {source="MA"} ! blood vessel layer
relationship: has_part UBERON:0002521 {source="cjm"} ! elastic tissue
relationship: has_part UBERON:0004237 {source="cjm"} ! blood vessel smooth muscle
relationship: surrounded_by UBERON:0005734 ! tunica adventitia of blood vessel
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg" xsd:anyURI

[Term]
id: UBERON:0002523
name: tunica intima
namespace: uberon
def: "The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]." [ISBN:0073040584, NCIT:C33820, Wikipedia:Tunica_intima]
subset: uberon_slim
synonym: "Bichat's tunic" RELATED [BTO:0002012]
synonym: "intima" RELATED [BTO:0002012]
synonym: "tunica intima vasorum" RELATED [BTO:0002012]
xref: BTO:0002012
xref: EMAPA:36297
xref: FMA:55589
xref: GAID:523
xref: MA:0002861
xref: MESH:D017539
xref: NCIT:C33820
xref: SCTID:8361002
xref: SCTID:87483006
xref: UMLS:C0162864 {source="ncithesaurus:Tunica_Intima"}
xref: Wikipedia:Tunica_intima
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004923 {source="FMA"} ! organ component layer
relationship: adjacent_to UBERON:0010161 {source="ISBN:0073040584"} ! lumen of blood vessel
relationship: has_part UBERON:0001986 ! endothelium
relationship: surrounded_by UBERON:0002522 {notes="check for exceptions, e.g. capillaries"} ! tunica media
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg" xsd:anyURI
property_value: editor_note "the FMA class represents a more generic layer which is the superclass of the layer found in both blood vessels and lymph vessels (and also endocardium) - we should probably follow this structure" xsd:string
property_value: editor_note "the FMA class represents a structure which may have both epithelium and fibroelastic connective tissue as parts" xsd:string
property_value: UBPROP:0000001 "The tunica intima (or just intima) is the innermost layer of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow. The inner coat (tunica intima) can be separated from the middle by a little maceration, or it may be stripped off in small pieces; but, on account of its friability, it cannot be separated as a complete membrane. It is a fine, transparent, colorless structure which is highly elastic, and, after death, is commonly corrugated into longitudinal wrinkles. The inner coat consists of: A layer of pavement endothelium, the cells of which are polygonal, oval, or fusiform, and have very distinct round or oval nuclei. This endothelium is brought into view most distinctly by staining with silver nitrate. A subendothelial layer, consisting of delicate connective tissue with branched cells lying in the interspaces of the tissue; in arteries of less than 2 mm. in diameter the subendothelial layer consists of a single stratum of stellate cells, and the connective tissue is only largely developed in vessels of a considerable size. An elastic or fenestrated layer, which consists of a membrane containing a net-work of elastic fibers, having principally a longitudinal direction, and in which, under the microscope, small elongated apertures or perforations may be seen, giving it a fenestrated appearance. It was therefore called by Henle the fenestrated membrane. This membrane forms the chief thickness of the inner coat, and can be separated into several layers, some of which present the appearance of a network of longitudinal elastic fibers, and others a more membranous character, marked by pale lines having a longitudinal direction. In minute arteries the fenestrated membrane is a very thin layer; but in the larger arteries, and especially in the aorta, it has a very considerable thickness. [WP,unvetted].[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Tunica_intima"}

[Term]
id: UBERON:0002530
name: gland
namespace: uberon
def: "An organ that functions as a secretory or excretory organ." [MGI:csmith, MP:0002163]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
synonym: "Druese" RELATED [BTO:0000522]
synonym: "glandula" RELATED OMO:0003011 [BTO:0000522, Wikipedia:Gland]
synonym: "glandular organ" EXACT [http://orcid.org/0000-0002-6601-2165]
xref: AAO:0000212
xref: AEO:0000096
xref: BTO:0000522
xref: EFO:0000797
xref: EHDAA2:0003096
xref: EHDAA:2161
xref: EHDAA:4475
xref: EHDAA:6522
xref: EMAPA:18425
xref: FBbt:00100317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:7146
xref: FMA:86294
xref: galen:Gland
xref: HAO:0000375
xref: MA:0003038
xref: MAT:0000021
xref: MIAA:0000021
xref: NCIT:C13319
xref: SCTID:134358001
xref: UMLS:C1285092 {source="ncithesaurus:Gland"}
xref: Wikipedia:Gland
xref: WikipediaCategory:Glands
is_a: UBERON:0000062 ! organ
relationship: capable_of GO:0046903 ! secretion
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: produces UBERON:0000463 ! organism substance
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/a1/Gray1026.png" xsd:anyURI
property_value: RO:0002171 UBERON:0001434
property_value: UBPROP:0000007 "glandular" xsd:string

[Term]
id: UBERON:0002532
name: epiblast (generic)
namespace: uberon
def: "In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA]." [Wikipedia:Epiblast, ZFIN:curator]
subset: early_development
subset: grouping_class
subset: uberon_slim
subset: vertebrate_core
synonym: "blastocyst" RELATED []
synonym: "ectoblast" RELATED [MP:0003886]
synonym: "epiblast" EXACT [VHOG:0000243]
synonym: "epiblastus" RELATED OMO:0003011 [Wikipedia:Epiblast]
synonym: "primitive ectoderm" RELATED [VHOG:0000243]
xref: BTO:0004593
xref: FMA:296704
xref: MAT:0000067
xref: MIAA:0000067
xref: VHOG:0000243
xref: Wikipedia:Epiblast
is_a: UBERON:0002050 ! embryonic structure
relationship: has_part CL:0000352 ! epiblast cell
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png" xsd:anyURI
property_value: editor_note "MP says - tissue that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper. In HOG, epiblast is part of primitive streak/blastpore, which is inconsistent with the MP definition of primitive streak as a ridge of the epiblast. Note that these terms, epiblast and hypoblast, are also used to describe layers of the avian embryonic blastoderm, but the layers so-named seem to be altogether different in these two kinds of vertebrate embryos(CVS). Consider obsoleting this as a grouping class" xsd:string
property_value: UBPROP:0000003 "In pregastrula zebrafish embryos, the epiblast is an inverted cup of cells that sits on top of a large yolk cell. (...) In amniote embryos (mammals and birds), gastrulation initiates in an epithelial layer called the epiblast. Cells in the epiblast undergo an epithelial to mesenchymal transition (EMT), migrate through the primitive streak (PS), and incorporate in the middle (mesoderm) or outer (endoderm) layer. The presumptive definitive endoderm (DE) cells invade and displace an outer layer of extraembryonic tissue cells, the hypoblast in chick and the visceral endoderm (VE) in mouse, which form supporting structures such as the yolk sac.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000243", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.042308.113344 Zorn AM, Wells JM, Vertebrate endoderm development and organ formation. Annual Review of Cell Developmental Biology (2009)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002533
name: post-anal tail bud
namespace: uberon
def: "The rapidly proliferating mass of cells at the caudal extremity of the embryo; remnant of the primitive node." [BTO:0001445]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "end bud" RELATED [BTO:0001445]
synonym: "tail bud" EXACT [ZFA:0000077]
synonym: "tail bud mesenchyme" RELATED [ZFA:0000077]
synonym: "tailbud" EXACT []
xref: AAO:0011104
xref: BTO:0001445
xref: EFO:0002748
xref: EHDAA2:0001976
xref: EHDAA:1595
xref: EMAPA:16580
xref: MAT:0000070
xref: MIAA:0000070
xref: TAO:0000077
xref: VHOG:0000201
xref: XAO:0000107
xref: ZFA:0000077
is_a: UBERON:0002050 ! embryonic structure
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
property_value: editor_note "See notes from https://github.com/obophenotype/uberon/wiki/The-neural-crest" xsd:string
property_value: UBPROP:0000001 "Rapidly proliferating mass of cells at the caudal extremity of the embryo. Its formation is reflected in a caudal carving of the posterior portion of the archenteric canal at NF stage 22. With its further outgrowth, the postanal gut primordium becomes stretched. Its lumen is in broad communication with the hindgut at NF stage 25.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011104", ontology="AAO", source="ISBN:0815318960", source="OMD:tail+bud"}
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (5) a larva or embryo with a postanal tail.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000201", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0002536
name: arthropod sensillum
namespace: uberon
def: "Sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organised unit with a largely bona-fide boundary.[FBbt]." [FBbt:00007152, Wikipedia:Sensillum]
subset: efo_slim
subset: uberon_slim
synonym: "sensillum" EXACT [FBbt:00007152, HAO:0000933]
xref: BTO:0001237
xref: EFO:0000939
xref: FBbt:00007152 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: HAO:0000933
xref: MAT:0000163
xref: MIAA:0000163
xref: TGMA:0000540
xref: Wikipedia:Sensillum
is_a: UBERON:0000020 ! sense organ
relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda
relationship: part_of UBERON:0001016 ! nervous system
property_value: editor_note "this term should be ceded to the arthropod anatomy ontology" xsd:string

[Term]
id: UBERON:0002537
name: hermaphrodite gonad
namespace: uberon
def: "A gonad with both testicular and ovarian aspects[WP]." [Wikipedia:Ovotestis]
subset: efo_slim
synonym: "glandula hermaphroditica" NARROW SENSU [Wikipedia:Ovotestis#In_gastropods]
synonym: "hermaphrodite genitalia" EXACT [GO:0040035]
synonym: "hermaphrodite gland" NARROW SENSU [Wikipedia:Ovotestis#In_gastropods]
synonym: "ovotestis" RELATED [BTO:0000981]
xref: BTO:0000981
xref: EFO:0000971
xref: MAT:0000165
xref: MIAA:0000165
xref: WBbt:0005178
xref: Wikipedia:Ovotestis
is_a: UBERON:0000991 ! gonad
intersection_of: UBERON:0000991 ! gonad
intersection_of: capable_of GO:0007283 ! spermatogenesis
intersection_of: capable_of GO:0048477 ! oogenesis
relationship: capable_of GO:0007283 ! spermatogenesis
relationship: capable_of GO:0048477 ! oogenesis
relationship: part_of UBERON:0007197 ! hermaphroditic organism

[Term]
id: UBERON:0002539
name: pharyngeal arch
namespace: uberon
def: "One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches." [http://orcid.org/0000-0002-6601-2165, PMID:16313389, ZFA:yb]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "arcus pharyngei" RELATED OMO:0003011 [Wikipedia:Pharyngeal_arch]
synonym: "branchial arch" NARROW [BTO:0001785, MP:0002884]
synonym: "pharyngeal arches" EXACT OMO:0003004 []
synonym: "visceral arch" RELATED []
xref: AAO:0010359
xref: BTO:0001785
xref: EFO:0000959
xref: EHDAA:571
xref: EMAPA:16117
xref: FMA:293015
xref: GAID:1292
xref: MAT:0000242
xref: MESH:D001934
xref: MIAA:0000242
xref: NCIT:C34249
xref: SCTID:308766004
xref: TAO:0001306
xref: UMLS:C0080322 {source="ncithesaurus:Pharyngeal_Arch"}
xref: VHOG:0000155
xref: Wikipedia:Pharyngeal_arch
xref: XAO:0000096
xref: ZFA:0001306
is_a: UBERON:0000481 ! multi-tissue structure
is_a: UBERON:0010188 {source="EHDAA2"} ! protuberance
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
relationship: developmentally_induced_by UBERON:0007690 {source="PMID:16313389"} ! early pharyngeal endoderm
relationship: only_in_taxon NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! Chordata
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0008814 ! pharyngeal arch system
relationship: part_of UBERON:0008816 {source="PMID:16313389"} ! embryonic head
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray41.png" xsd:anyURI
property_value: UBPROP:0000001 "One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010359", ontology="AAO", source="NLM:branchial+arch"}
property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000155", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M and Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000013 "Numbered cranial to caudal. different in mammals. branchial arch = ZFA:0001613 pharyngeal arch 3-7. generally gill arch 1 = pharyngeal arch 3. terminology varies as to whether branchial arch follows gill or pharyngeal numbering" xsd:string

[Term]
id: UBERON:0002546
name: cranial placode
namespace: uberon
def: "Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic." [http://www.ncbi.nlm.nih.gov/books/NBK53175/, https://github.com/obophenotype/uberon/issues/135, https://github.com/seger/aao/issues/4, https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/p/obo/xenopus-anatomy-xao-term-requests/11/]
subset: efo_slim
synonym: "cranial placodes" RELATED OMO:0003004 [XAO:0000305]
synonym: "ectodermal cranial placode" EXACT [UBERON:cjm]
synonym: "ectodermal placode" BROAD INCONSISTENT [FMA:293966, PMID:22512454]
synonym: "placode" BROAD [Wikipedia:Placode]
xref: AAO:0010466
xref: EFO:0001650
xref: FMA:293966
xref: MAT:0000369
xref: MIAA:0000369
xref: XAO:0000305
is_a: UBERON:0005085 {source="cjm"} ! ectodermal placode
relationship: only_in_taxon NCBITaxon:7711 {source="PMID:11523831", source="PMID:22512454"} ! Chordata
relationship: part_of UBERON:0000033 ! head
property_value: editor_note "Do not merge with neurogenic placode" xsd:string
property_value: UBPROP:0000008 "Comparisons of developmental gene expression suggest that the anterior ectoderm in amphioxus may be homologous to the vertebrate olfactory placode, the only vertebrate placode with primary, not secondary, neurons" xsd:string {source="PMID:11523831"}
property_value: UBPROP:0000013 "The term placode or placodes also applies to developing organs such as teeth, mammary glands, hair follicles, feathers and scales. We include a separate parent class for this. to avoid confusion, we include neurogenic placode as a subclass" xsd:string

[Term]
id: UBERON:0002548
name: larva
namespace: uberon
def: "A distinct juvenile form many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle." [Wikipedia:Larva]
subset: uberon_slim
synonym: "ammocoete" NARROW [Wikipedia:Larva]
synonym: "bipinnaria" NARROW [Wikipedia:Larva]
synonym: "caterpillar" NARROW [Wikipedia:Larva]
synonym: "glochidium" NARROW [Wikipedia:Larva]
synonym: "grub" NARROW [Wikipedia:Larva]
synonym: "larval organism" EXACT [TAO:0002048]
synonym: "leptocephalus" NARROW [Wikipedia:Larva]
synonym: "maggot" NARROW [Wikipedia:Larva]
synonym: "naiad" NARROW [Wikipedia:Larva]
synonym: "nymph" NARROW [Wikipedia:Larva]
synonym: "planula" NARROW [Wikipedia:Larva]
synonym: "tadpole" NARROW [Wikipedia:Larva]
synonym: "trochophore" NARROW [Wikipedia:Larva]
synonym: "veliger" NARROW [Wikipedia:Larva]
synonym: "wriggler" NARROW [Wikipedia:Larva]
synonym: "zoea" NARROW [Wikipedia:Larva]
xref: AEO:0000126
xref: BTO:0000707
xref: FBbt:00001727 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: HAO:0000459
xref: MESH:D007814 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: TAO:0002048
xref: Wikipedia:Larva
is_a: UBERON:0000468 ! multicellular organism
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: existence_starts_and_ends_during UBERON:0000069 ! larval stage
relationship: existence_starts_and_ends_during UBERON:0000069 ! larval stage
relationship: has_quality PATO:0001185 ! larval
property_value: editor_note "TODO discriminate between stages and organisms" xsd:string
property_value: UBPROP:0000001 "Whole organism that is premetamorphic or a very immature individual.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002048", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000007 "larval" xsd:string

[Term]
id: UBERON:0002553
name: anatomical cavity
namespace: uberon
def: "Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina." [FMA:67552]
subset: upper_level
synonym: "cavity" BROAD []
xref: BIRNLEX:1011
xref: EMAPA:37442 {source="MA:th"}
xref: FMA:67552
xref: galen:Cavity
xref: MA:0002447
xref: NCIT:C34007
is_a: UBERON:0000464 ! anatomical space
relationship: location_of UBERON:0000463 ! organism substance

[Term]
id: UBERON:0002558
name: organ cavity
namespace: uberon
subset: upper_level
synonym: "cavity of organ" EXACT [FMA:12237]
xref: BIRNLEX:1019
xref: FMA:12237
xref: SCTID:362606005
is_a: UBERON:0002553 ! anatomical cavity

[Term]
id: UBERON:0002561
name: lumen of central nervous system
namespace: uberon
def: "The cavity that is enclosed by the central nervous system. In vertebrates this is the cavity that includes as parts ventricular cavities and the central canal of the spinal cord that develops from the lumen of the neura tube." [https://orcid.org/0000-0002-6601-2165]
synonym: "cavity of neuraxis" EXACT [FMA:75007]
synonym: "cavity of ventricular system of neuraxis" EXACT [FMA:75007]
synonym: "neuraxis cavity" EXACT [FMA:75007]
synonym: "neuraxis lumen" EXACT []
xref: BIRNLEX:1029
xref: FMA:75007
is_a: UBERON:0002558 ! organ cavity
intersection_of: UBERON:0002558 ! organ cavity
intersection_of: luminal_space_of UBERON:0001017 ! central nervous system
relationship: develops_from UBERON:0003842 {gci_relation="part_of", gci_filler="NCBITaxon:7742", source="cjm"} ! neural tube lumen
relationship: luminal_space_of UBERON:0001017 ! central nervous system
relationship: part_of UBERON:0001017 ! central nervous system
property_value: RO:0002175 NCBITaxon:569425 {source="DOI:10.1186/s12983-014-0089-2"}

[Term]
id: UBERON:0002616
name: regional part of brain
namespace: uberon
def: "Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia." [BIRNLEX:1167]
subset: non_informative
synonym: "anatomical structure of brain" EXACT [OBOL:automatic]
synonym: "biological structure of brain" EXACT [OBOL:automatic]
synonym: "brain anatomical structure" EXACT [OBOL:automatic]
synonym: "brain biological structure" EXACT [OBOL:automatic]
synonym: "brain part" EXACT []
synonym: "neuraxis segment" EXACT [FMA:55676]
synonym: "neuroanatomical region" EXACT []
synonym: "segment of brain" EXACT [BIRNLEX:1167]
xref: BIRNLEX:1167
xref: FMA:55676
xref: NCIT:C13031
xref: SCTID:384763002
xref: UMLS:C0445620 {source="ncithesaurus:Brain_Part"}
is_a: UBERON:0000073 ! regional part of nervous system
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000481 ! multi-tissue structure
intersection_of: part_of UBERON:0000955 ! brain
relationship: composed_primarily_of UBERON:0003714 ! neural tissue
relationship: part_of UBERON:0000955 ! brain

[Term]
id: UBERON:0002726
name: cervical spinal cord
namespace: uberon
def: "A spinal cord segment that adjacent_to a cervical region." [OBOL:automatic]
subset: human_reference_atlas
synonym: "cervical segment of spinal cord" EXACT [FMA:71166]
synonym: "cervical segments of spinal cord [1-8]" EXACT [FMA:71166]
synonym: "cervical spinal cord" EXACT [FMA:71166]
synonym: "pars cervicalis medullae spinalis" EXACT OMO:0003011 [FMA:71166, FMA:TA]
synonym: "segmenta cervicalia medullae spinalis [1-8" EXACT OMO:0003011 [FMA:71166, FMA:TA]
xref: BIRNLEX:1499
xref: FMA:71166
xref: MA:0003081
xref: MESH:D066193 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: NCIT:C12892
xref: neuronames:1654
xref: SCTID:180960003
xref: UMLS:C0581619 {source="BIRNLEX:1499", source="ncithesaurus:Cervical_Spinal_Cord"}
xref: UMLS:C1278837 {source="BIRNLEX:1499"}
is_a: UBERON:0005844 ! spinal cord segment
intersection_of: UBERON:0005844 ! spinal cord segment
intersection_of: adjacent_to UBERON:0005434 ! cervical region
relationship: adjacent_to UBERON:0005434 ! cervical region
relationship: only_in_taxon NCBITaxon:8287 ! Sarcopterygii
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0002925
name: trigeminal nucleus
namespace: uberon
def: "A nucleus of brain that is part of a trigeminal nuclear complex." [OBOL:automatic]
subset: uberon_slim
synonym: "nucleus mesencephalicus nervi trigemini" RELATED [BTO:0001074]
synonym: "nucleus mesencephalicus trigeminalis" RELATED [BTO:0001074]
synonym: "nucleus of trigeminal nuclear complex" EXACT [FMA:71247]
synonym: "nucleus tractus mesencephali nervi trigeminalis" RELATED [BTO:0001074]
synonym: "trigeminal nuclear complex nucleus" EXACT [FMA:71247]
synonym: "trigeminal nucleus" EXACT [FMA:71248]
synonym: "trigeminal V nucleus" EXACT [MA:0001028]
xref: BM:V
xref: BTO:0001074
xref: CALOHA:TS-2077
xref: EMAPA:35883
xref: EV:0100271
xref: FMA:71247
xref: GAID:604
xref: http://uri.neuinfo.org/nif/nifstd/nifext_11
xref: MA:0001028
xref: MESH:D014278
xref: NCIT:C12807
xref: SCTID:280164007
xref: UMLS:C0040999 {source="ncithesaurus:Trigeminal_Nucleus"}
xref: VHOG:0001353
is_a: UBERON:0000126 ! cranial nerve nucleus
intersection_of: UBERON:0002308 ! nucleus of brain
intersection_of: part_of UBERON:0007641 ! trigeminal nuclear complex
relationship: extends_fibers_into UBERON:0001645 ! trigeminal nerve
relationship: part_of UBERON:0007641 ! trigeminal nuclear complex
property_value: UBPROP:0000012 "massive inconsistencies between GO, MA, wikipedia. Part of pons in MA, but this leads to inconsistencies with ABA." xsd:string {external_ontology="GO", url="https://github.com/obophenotype/mouse-anatomy-ontology/issues/58"}

[Term]
id: UBERON:0003023
name: pontine tegmentum
namespace: uberon
def: "Dorsal portion of the pons, containing cranial nervee nuclei, ascending and descending tracts and reticular nuclei. It is continuous with the reticular formation of the medulla (Carpenter, A Core Text of Neuroanatomy, 3rd ed, 1985, pg 133)." [BIRNLEX:923]
subset: human_reference_atlas
subset: uberon_slim
synonym: "dorsal pons" EXACT []
synonym: "dorsal portion of pons" EXACT [FMA:71108]
synonym: "pars dorsalis pontis" RELATED OMO:0003011 [NeuroNames:557]
synonym: "pars posterior pontis" RELATED OMO:0003011 [NeuroNames:557]
synonym: "tegmental portion of pons" EXACT [FMA:71108]
synonym: "tegmentum of pons" EXACT [FMA:71108]
synonym: "tegmentum pontis" EXACT OMO:0003011 [FMA:71108, FMA:TA]
synonym: "tegmentum pontis" RELATED OMO:0003011 [Wikipedia:Pontine_tegmentum]
xref: BAMS:PTg
xref: BIRNLEX:923
xref: DHBA:12416
xref: FMA:71108
xref: HBA:9135
xref: MESH:D065821 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: neuronames:557 {source="BIRNLEX:923"}
xref: SCTID:362401009
xref: UMLS:C0228426 {source="BIRNLEX:923"}
xref: Wikipedia:Pontine_tegmentum
is_a: UBERON:0000064 ! organ part
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: has_part UBERON:0002047 ! pontine raphe nucleus
relationship: has_part UBERON:0002128 ! superior olivary complex
relationship: has_part UBERON:0002148 ! locus ceruleus
relationship: has_part UBERON:0002149 ! superior salivatory nucleus
relationship: part_of UBERON:0000988 ! pons
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_F_Brain.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_M_Brain.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/9/9c/Brainstem_Abducens.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000009 "involved in the initiation of REM sleep [Wikipedia:Pontine_tegmentum]" xsd:string

[Term]
id: UBERON:0003037
name: septum
namespace: uberon
def: "A wall, dividing a cavity or structure into smaller ones[WP]." [Wikipedia:Septum]
comment: general anatomical term in FMA
subset: pheno_slim
synonym: "septa" EXACT OMO:0003004 []
xref: AAO:0011127
xref: FMA:86461
xref: Wikipedia:Septum
is_a: UBERON:0000061 ! anatomical structure
relationship: located_in UBERON:0002553 ! anatomical cavity
property_value: UBPROP:0000007 "septal" xsd:string

[Term]
id: UBERON:0003038
name: thoracic spinal cord
namespace: uberon
def: "The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]." [Wikipedia:Thoracic_spinal_cord]
subset: human_reference_atlas
subset: uberon_slim
synonym: "pars thoracica medullae spinalis" EXACT OMO:0003011 [FMA:71167, FMA:TA]
synonym: "segmenta thoracica medullae spinalis [1-12]" EXACT OMO:0003011 [FMA:71167, FMA:TA]
synonym: "thoracic region of spinal cord" EXACT [FMA:71167]
synonym: "thoracic segment of spinal cord" EXACT [FMA:71167]
synonym: "thoracic segments of spinal cord [1-12]" EXACT [FMA:71167]
synonym: "thoracic spinal cord" EXACT [FMA:71167]
xref: BIRNLEX:966
xref: FMA:71167
xref: MA:0003082
xref: NCIT:C12894
xref: neuronames:1718
xref: SCTID:278750009
xref: UMLS:C0581620 {source="ncithesaurus:Thoracic_Spinal_Cord", source="BIRNLEX:966"}
xref: Wikipedia:Thoracic_spinal_cord
is_a: UBERON:0005844 ! spinal cord segment
intersection_of: UBERON:0005844 ! spinal cord segment
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0008231 ! dorsal thoracic segment of trunk
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/68/Gray820.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003052
name: midbrain-hindbrain boundary
namespace: uberon
def: "The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate." [GO:0021555]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "isthmic organizer territory" RELATED [XAO:0000016]
synonym: "isthmo-cerebellar region" RELATED [VHOG:0000649]
synonym: "isthmus" RELATED []
synonym: "isthmus/MHB" RELATED [Geisha:syn, NCBITaxon:8782]
synonym: "MHB" EXACT []
synonym: "mid-hindbrain boundary" EXACT []
synonym: "mid-hindbrain junction" EXACT []
synonym: "midbrain hindbrain boundary" EXACT []
xref: AAO:0011064
xref: DMBA:16810
xref: EHDAA2:0004395
xref: EHDAA:5789
xref: EMAPA:32857
xref: NCIT:C93172
xref: neuronames:2076
xref: TAO:0000042
xref: VHOG:0000649
xref: XAO:0000016
xref: ZFA:0000042
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0007651 {inconsistent_with="ZFA", source="https://sourceforge.net/p/obo/zebrafish-anatomy-zfa-term-requests/106/"} ! anatomical junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: overlaps UBERON:0001891 ! midbrain
intersection_of: overlaps UBERON:0002028 ! hindbrain
relationship: develops_from UBERON:0009615 ! midbrain hindbrain boundary neural plate
relationship: immediate_transformation_of UBERON:0009615 {source="ZFA"} ! midbrain hindbrain boundary neural plate
relationship: overlaps UBERON:0001891 ! midbrain
relationship: overlaps UBERON:0002028 ! hindbrain
relationship: part_of UBERON:0000955 {source="ZFA"} ! brain
property_value: editor_note "consider adding class for organizer. Consider adding separate class for isthmus as a structure" xsd:string
property_value: UBPROP:0000003 "Lampreys also have an MHB [midbrain hindbrain boundary], expressing a similar repertoire of regulatory gene cognates as in gnathostomes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000649", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.008 Murakami Y, Uchida K, Rijli FM and Kuratani S, Evolution of the brain developmental plan: Insights from agnathans. Developmental Biology (2005)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003055
name: periderm
namespace: uberon
def: "A temporary epithelium that derives from the outer layer of the ectdoerm and is shed once the inner layer differentiates to form a true epidermis." [ISBN:9780878932504]
subset: pheno_slim
subset: uberon_slim
synonym: "epidermis epithelial layer" RELATED []
synonym: "epidermis outer layer" RELATED []
synonym: "epitrichium" RELATED [MP:0013530]
synonym: "EVL" RELATED [ZFA:0001185]
synonym: "periderm" RELATED []
synonym: "skin periderm" EXACT [EHDAA2:0001846]
xref: BTO:0003377 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: EHDAA2:0001846
xref: EHDAA:6538
xref: FMA:295662
xref: NCIT:C34247
xref: TAO:0001185
xref: UMLS:C1518973 {source="ncithesaurus:Periderm"}
xref: VHOG:0001680
xref: XAO:0000029
xref: ZFA:0001185
is_a: UBERON:0000487 {source="EHDAA2"} ! simple squamous epithelium
is_a: UBERON:0010371 ! ecto-epithelium
relationship: develops_from UBERON:0007383 {source="ZFA"} ! enveloping layer of ectoderm
relationship: part_of UBERON:0002199 {source="EHDAA2"} ! integument
property_value: UBPROP:0000001 "The outermost epidermal layer covering the fish at embryonic stages; derived from the EVL and thought to eventually be replaced by the superficial stratum of the epidermis. Sometimes used synonymously with EVL. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001185", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000002 "relationship type change: OBO_REL:part_of ectoderm (TAO:0000016) CHANGED TO: develops_from ectoderm (UBERON:0000924)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001185", ontology="TAO"}
property_value: UBPROP:0000008 "In mice, the first non-basal layer formed at ~E9.5; it is a temporary structure composed of simple squamous epithelium that serves as the first barrier to the embryo's physical environment, exists throughout the entire keratinocyte stratification process, and sheds off at ~E17, when it is replaced by corneocytes[MP]" xsd:string
property_value: UBPROP:0000011 "In some mammals, Eyelid Fusion is thought to be driven by a population of cells which are derived from the periderm, the outermost layer of the developing epidermis" xsd:string
property_value: UBPROP:0000011 "Originally the epidermis is one layer thick, in most vertebrates it soon becomes a two-layered structure. The outer layer gives rise to the periderm. The periderm goes through distinct developmental phases and is ultimately sloughed into the amniotic fluid when differentiation of the underlying epidermal layers is complete. The function of the periderm is not known, but is thought to be related to transport/exchange between the fetus and the amniotic fluid (http://courses.washington.edu/hubio567/devbio/periderm.html)" xsd:string

[Term]
id: UBERON:0003056
name: pre-chordal neural plate
namespace: uberon
def: "The portion of neural plate anterior to the mid-hindbrain junction." [XB:curator]
synonym: "anterior neural plate" RELATED []
xref: AAO:0011084
xref: TAO:0007016
xref: VHOG:0001200
xref: XAO:0000045
xref: ZFA:0007016
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
relationship: anterior_to UBERON:0009615 ! midbrain hindbrain boundary neural plate
relationship: part_of UBERON:0003075 ! neural plate
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001200", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003057
name: chordal neural plate
namespace: uberon
def: "The portion of neural plate posterior to the mid-hindbrain junction." [XB:curator]
synonym: "posterior neural plate" RELATED []
xref: TAO:0007017
xref: VHOG:0001201
xref: XAO:0000046
xref: ZFA:0007017
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0003075 ! neural plate
relationship: posterior_to UBERON:0009615 ! midbrain hindbrain boundary neural plate
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001201", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003059
name: presomitic mesoderm
namespace: uberon
def: "Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form." [ZFIN:curator]
subset: efo_slim
subset: pheno_slim
synonym: "presumptive somite mesoderm" RELATED []
synonym: "PSM" RELATED []
synonym: "segmental plate" EXACT []
synonym: "somitogenic mesoderm" RELATED []
synonym: "somitomeric mesoderm" RELATED [GO:0002075]
synonym: "unsegmented mesenchyme" RELATED [VHOG:0000559]
synonym: "unsegmented paraxial mesoderm" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: AAO:0011086
xref: EFO:0001982
xref: EMAPA:16189
xref: EMAPA:16752
xref: TAO:0000279
xref: VHOG:0000559
xref: XAO:0000057
xref: ZFA:0000279
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0005423 ! developing anatomical structure
intersection_of: has_potential_to_develop_into UBERON:0002329 ! somite
intersection_of: immediate_transformation_of UBERON:0007282 ! presumptive segmental plate
relationship: develops_from UBERON:0007282 ! presumptive segmental plate
relationship: has_potential_to_develop_into UBERON:0002329 ! somite
relationship: immediate_transformation_of UBERON:0007282 {source="Bgee:AN"} ! presumptive segmental plate
relationship: part_of UBERON:0003077 ! paraxial mesoderm
property_value: UBPROP:0000001 "Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000279", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000559", ontology="VHOG", source="DOI:10.1006/dbio.2001.0460 Schubert M, Holland LZ, Dale Stokes M and Holland ND, Three Amphoxius Wnt Genes (AmphiWnt3, AmphiWnt5, and AmphiWnt6) Associated with the Tail Bud: the Evolution of Somitogenesis in Chordates. Developmental Biology (2001)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003060
name: pronephric duct
namespace: uberon
def: "In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]." [Wikipedia:Pronephric_duct]
comment: The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150]
subset: uberon_slim
synonym: "archinephric duct" RELATED [VHOG:0000082]
synonym: "ductus pronephricus" RELATED OMO:0003011 [Wikipedia:Pronephric_duct]
synonym: "pronephric ducts" RELATED OMO:0003004 [ZFA:0000150]
xref: AAO:0011088
xref: BTO:0005991 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C34279
xref: SCTID:361406002
xref: TAO:0000150
xref: UMLS:C1283945 {source="ncithesaurus:Pronephric_Duct"}
xref: VHOG:0000082
xref: Wikipedia:Pronephric_duct
xref: XAO:0000063
xref: ZFA:0000150
is_a: UBERON:0009201 {source="GO"} ! nephric duct
is_a: UBERON:0012275 ! meso-epithelium
relationship: develops_from UBERON:0003064 {source="Wikipedia"} ! intermediate mesoderm
relationship: develops_from UBERON:0005721 {source="XAO"} ! pronephric mesoderm
relationship: part_of UBERON:0002120 ! pronephros
property_value: UBPROP:0000001 "Duct of the embryonic kidney, present bilaterally ventral to the somites and leading to the anal region where it empties separately from, and just posterior to the anus. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000150", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "(...) in all craniates, the archinephric duct develops in embryogeny.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.686", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003061
name: blood island
namespace: uberon
def: "Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]." [Wikipedia:Blood_island_of_umbilical_vesicle]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "blood islands" EXACT OMO:0003004 []
synonym: "caudal hematopoietic tissue" RELATED []
synonym: "posterior blood island" RELATED []
synonym: "posterior ICM" RELATED []
synonym: "VBI" RELATED []
synonym: "ventral blood island" RELATED []
synonym: "ventral lateral plate mesoderm" BROAD []
xref: AAO:0011006
xref: EFO:0003489
xref: EHDAA:207
xref: NCIT:C34113
xref: TAO:0000094
xref: TE:E5.11.2.0.0.0.4
xref: UMLS:C1511224 {source="ncithesaurus:Blood_Island"}
xref: VHOG:0000085
xref: Wikipedia:Blood_island_of_umbilical_vesicle
xref: XAO:0000067
xref: ZFA:0000094
is_a: UBERON:0006598 ! presumptive structure
relationship: develops_from UBERON:0003081 ! lateral plate mesoderm
relationship: has_potential_to_develop_into UBERON:0002390 ! hematopoietic system
property_value: UBPROP:0000001 "Nests of developing blood cells arising late in the segmentation period from the intermediate mass, and located in the anterior-ventral tail, just posterior to the yolk extension. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000094", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011006", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000002 "relationship loss: part_of intermediate cell mass of mesoderm (TAO:0000033)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000094", ontology="TAO"}
property_value: UBPROP:0000003 "Small clusters of mesodermal cells called blood islands mark the embryonic debut of the cardiovascular system (in vertebrates) (reference 1); In birds and mammals, primitive hemangioblasts are extraembryonic, populating the yolk sac as the so-called blood islands (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000085", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.450, DOI:10.1146/annurev.cellbio.22.010605.093317 Hartenstein V, Blood cells and blood cell development in the animal kingdom. Annual Review of Cell and Developmental Biology (2006)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "EHDAA2 distinguishes 3 types, but does not have a superclass. The VHOG class may refer to yolk sac" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0003063
name: prechordal plate
namespace: uberon
alt_id: UBERON:0004881
def: "A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue." [ISBN:0838580343, MP:0004387]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "head mesenchyme" BROAD [XAO:0000079]
synonym: "head mesoderm" BROAD [XAO:0000079]
xref: AAO:0011085
xref: EHDAA2:0001493
xref: EHDAA:181
xref: FMA:295532
xref: TAO:0000060
xref: VHOG:0000086
xref: Wikipedia:Prechordal_plate
xref: XAO:0000079
xref: ZFA:0000060
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0034878 ! prechordal mesoderm
relationship: part_of UBERON:0003068 {source="ZFA"} ! axial mesoderm
relationship: transformation_of UBERON:0034878 {todo="PMID:16313393"} ! prechordal mesoderm
property_value: editor_note "TODO - check; developmental relationship to anterior hypoblast in ZFA?" xsd:string
property_value: UBPROP:0000001 "Axial hypoblast located anterior to the chorda mesoderm; the polster is its most anterior region. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000060", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Axial mesoderm that lies anterior to the notochord and that underlies the forebrain. [Amphioxus_goosecoid_and_the_evolution_of_the_head_organizer_and_prechordal_plate._Evolution_and_Development_(2008)_2(6):303-310, Neidert_AH, Panopoulou_G_and_Langeland_JA][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000086", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "There are two opposing models that can potentially explain the differences in gsc (goosecoid) expression between amphioxus and vertebrates. In one model, the vertebrate gsc expression pattern more closely resembles the common ancestral state and the amphioxus gsc expression pattern is a derivation associated with its unique morphology. (...) In an alternate model, the amphioxus gsc expression pattern most closely represents the common ancestral state and the vertebrate pattern is derived. This model suggests that the evolution of vertebrates was accompanied by the segregation of gsc expression, from a more general domain underlying the entire brain anlage to a distinct forebrain organizer domain and subsequent prechordal plate. We feel this second model is more parsimonious than the first model in that what would be novel anterior gsc expression in vertebrates directly correlates with a novel vertebrate anterior structure, the prechordal plate.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000086", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00073.x Neidert AH, Panopoulou G and Langeland JA, Amphioxus goosecoid and the evolution of the head organizer and prechordal plate. Evolution and Development (2008)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003064
name: intermediate mesoderm
namespace: uberon
def: "The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." [GOC:curators, Wikipedia:Intermediate_mesoderm]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "IM" RELATED []
synonym: "intermediate mesenchyme" RELATED [https://github.com/obophenotype/uberon/wiki/The-neural-crest]
synonym: "intermediate plate" RELATED [EMAPA:16178]
synonym: "intermediate plate mesoderm" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "mesenchyma intermedium" RELATED OMO:0003011 [Wikipedia:Intermediate_mesoderm]
xref: AAO:0010575
xref: EMAPA:16056
xref: EMAPA:16178
xref: FMA:293147
xref: NCIT:C34193
xref: SCTID:361476001
xref: TAO:0001206
xref: UMLS:C1284010 {source="ncithesaurus:Intermediate_Mesoderm"}
xref: VHOG:0000087
xref: Wikipedia:Intermediate_mesoderm
xref: XAO:0000085
xref: ZFA:0001206
is_a: UBERON:0002050 ! embryonic structure
relationship: adjacent_to UBERON:0003077 ! paraxial mesoderm
relationship: adjacent_to UBERON:0003081 ! lateral plate mesoderm
relationship: develops_from UBERON:0000926 {source="XAO"} ! mesoderm
relationship: part_of UBERON:0000926 {source="AAO"} ! mesoderm
relationship: part_of UBERON:0005256 {source="EMAPA"} ! trunk mesenchyme
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI
property_value: UBPROP:0000001 "Mesoderm between somite and lateral plate. Traditionally thought to give rise to the urogenital system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010575", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "(...)the mesoderm of a developing vertebrate transitionally differentiates into the following sub-types: Chordamesoderm (also known as axial mesoderm) which later on gives rise to notochord in all chordates, Paraxial mesoderm, Intermediate mesoderm, Lateral plate mesoderm (reference 1); The mesoderm is present in Bilateria, therefore they are sometimes called triploblasts. Ectoderm and endoderm are usually organized as epithelial layers, while mesoderm can be epithelial or a compact, three-dimensional tissue.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000087", ontology="VHOG", source="Wikipedia:Mesoderm, ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.43", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "all AOs differ in the relationship between this structure and the mesoderm; in ZFA it is a subclass (and this is implied by the GO definition and GO relationships), in AAO it is part of, and in EHDAA2 it develops from the mesoderm (but in EHDAA2 the naming convention is to use 'paraxial mesenchyme', rather than 'paraxial mesoderm')." xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0003067
name: dorsolateral placode
namespace: uberon
def: "Lateral neurogenic placodes positioned dorsal of the epibranchial placodes." [ZFIN:curator]
comment: The only remaining dorsolateral placode in land vertebrates is the otic/octaval placode
synonym: "dorsolateral placodes" EXACT OMO:0003004 [ZFA:0001310]
xref: TAO:0001310
xref: VHOG:0000103
xref: XAO:0000187
xref: ZFA:0001310
is_a: UBERON:0009955 {source="NCBIBook:NBK53175"} ! neurogenic placode
relationship: dorsal_to UBERON:0003078 ! epibranchial placode
property_value: UBPROP:0000003 "In summary, the collective term 'placodes' refers to some rather different structures, probably with different evolutionary origins. Some sensory placodes (at least the otic and olfactory) may have homologues in basal chordates. Even if this is so, it is apparent that they were elaborated considerably during early vertebrate evolution. Epibranchial and dorsolateral placodes appear to be new; we infer that their origin depended on the evolution of specific inductive signals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000103", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003068
name: axial mesoderm
namespace: uberon
def: "The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." [GO:0048318, Wikipedia:Chordamesoderm]
subset: efo_slim
subset: uberon_slim
synonym: "chordamesoderm" RELATED [Wikipedia:Chordamesoderm]
xref: AAO:0011017
xref: EFO:0003647
xref: TAO:0001204
xref: VHOG:0000107
xref: Wikipedia:Chordamesoderm
xref: XAO:0000205
xref: ZFA:0001204
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0000926 ! mesoderm
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
relationship: part_of UBERON:0000926 ! mesoderm
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI
property_value: UBPROP:0000001 "The portion of the mesoderm underlying the midline of the embryo. [Gastrulation:_From_cells_to_embryo_(2004)_Cold_Spring_Harbor, Glossary_XV, New_York:_Cold_Spring_Harbor_Laboratory_Press, Stern_CD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000107", ontology="VHOG", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003070
name: trigeminal placode complex
namespace: uberon
def: "A neurogenic placode that arises at the level of the midbrain-hindbrain boundary and develops into a trigeminal ganglion." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/693, PMID:22512454]
subset: efo_slim
synonym: "profundus placode" RELATED INCONSISTENT [ISBN:0471888893]
synonym: "profundus V placode" RELATED INCONSISTENT [ISBN:0471888893]
synonym: "trigeminal placode" EXACT [EHDAA2:0004209, VHOG:0000109, XAO:0000225, ZFA:0000162]
synonym: "trigeminal placodes" RELATED OMO:0003004 [ZFA:0000162]
synonym: "trigeminal V placode" EXACT []
xref: EFO:0003433
xref: EHDAA2:0004209
xref: TAO:0000162
xref: VHOG:0000109
xref: XAO:0000225
xref: ZFA:0000162
is_a: UBERON:0003067 {source="ISBN:0471888893"} ! dorsolateral placode
relationship: has_potential_to_developmentally_contribute_to UBERON:0003942 ! somatosensory system
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/ANiknejad
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly
property_value: UBPROP:0000001 "The ectodermal precursor of the trigeminal ganglion. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24.[XAO]" xsd:string {ontology="XAO"}
property_value: UBPROP:0000001 "The ectodermal rudiment of the trigeminal ganglion, distinguishable during much of the segmentation period. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000162", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "The dorsolateral placodes (trigeminal and vestibular) develop from ectoderm lateral to the brain (...). In summary, the collective term 'placodes' refers to some rather different structures, probably with different evolutionary origins. Some sensory placodes (at least the otic and olfactory) may have homologues in basal chordates. Even if this is so, it is apparent that they were elaborated considerably during early vertebrate evolution. Epibranchial and dorsolateral placodes appear to be new; we infer that their origin depended on the evolution of specific inductive signals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000109", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000013 "Consider naming this 'trigeminal placode complex'. Also, Fig9-5 of ISBN:0471888893 calls this the profundus placode; XAO says 'profundal and the trigeminal ganglia are separate distally but fused at their proximal end...'" xsd:string

[Term]
id: UBERON:0003071
name: eye primordium
namespace: uberon
alt_id: UBERON:0005060
def: "Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles." [GO:0046619, ZFA:0000570]
subset: efo_slim
synonym: "eye anlage" RELATED [XAO:0000227]
synonym: "eye field" RELATED []
synonym: "eye placode" EXACT [OBOL:automatic]
synonym: "occular primordium" EXACT []
synonym: "ocular primordium" EXACT []
synonym: "optic field" RELATED []
synonym: "optic placode" EXACT [GO:0046619]
synonym: "optic placode of camera-type eye" EXACT [GO:0046619, https://orcid.org/0000-0002-6601-2165]
synonym: "optic placodes" RELATED OMO:0003004 []
synonym: "optic primordium" EXACT []
xref: AAO:0011038
xref: EFO:0003541
xref: EHDAA2:0004431
xref: TAO:0000570
xref: XAO:0000227
xref: XAO:0004090
xref: ZFA:0000570
is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium
is_a: UBERON:0001048 ! primordium
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0006598 ! presumptive structure
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0001048 ! primordium
intersection_of: has_potential_to_develop_into UBERON:0000019 ! camera-type eye
relationship: develops_from UBERON:0003056 ! pre-chordal neural plate
relationship: has_potential_to_develop_into UBERON:0000019 ! camera-type eye
relationship: part_of UBERON:0003056 {source="PMID:16496288", source="XAO"} ! pre-chordal neural plate
property_value: UBPROP:0000012 "TODO - check that GO's optic placode is the same as ZFA's eye primordium; we may want to have separate term for ocular primordium precursor. XAO has both optic field and eye primordium." xsd:string {external_ontology="GO"}

[Term]
id: UBERON:0003072
name: optic cup
namespace: uberon
def: "Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]." [MP:0004269, Wikipedia:Optic_cup_(embryology), ZFA:0001202]
subset: pheno_slim
subset: vertebrate_core
synonym: "eye cup" RELATED []
synonym: "eyecup" RELATED [BTO:0005351]
synonym: "ocular cup" RELATED [VHOG:0000167]
synonym: "ophtalmic cup" RELATED [BTO:0005351]
xref: BTO:0005351
xref: EHDAA2:0001303
xref: EHDAA:2912
xref: EMAPA:16674
xref: NCIT:C34233
xref: SCTID:308789007
xref: TAO:0001202
xref: UMLS:C0231109 {source="ncithesaurus:Optic_Cup"}
xref: VHOG:0000167
xref: ZFA:0001202
is_a: UBERON:0000481 ! multi-tissue structure
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: developmentally_induced_by UBERON:0003073 ! lens placode
relationship: develops_from UBERON:0004128 {source="ZFA"} ! optic vesicle
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0010312 {source="ZFA"} ! immature eye
property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000167", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003073
name: lens placode
namespace: uberon
def: "A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]." [Wikipedia:Lens_placode, ZFIN:curator]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "lens placodes" RELATED OMO:0003004 [ZFA:0000122]
synonym: "placoda lentis" RELATED OMO:0003011 [Wikipedia:Lens_placode]
xref: AAO:0011055
xref: EFO:0003494
xref: EHDAA2:0000982
xref: EHDAA:2908
xref: EMAPA:16672
xref: FMA:296767
xref: NCIT:C34202
xref: TAO:0000122
xref: UMLS:C1517770 {source="ncithesaurus:Lens_Placodes"}
xref: VHOG:0000166
xref: Wikipedia:Lens_placode
xref: XAO:0000240
xref: ZFA:0000122
is_a: UBERON:0002546 ! cranial placode
is_a: UBERON:0006598 ! presumptive structure
is_a: UBERON:0010312 ! immature eye
is_a: UBERON:0011814 {source="NCBIBook:NBK53175"} ! non-neurogenic ectodermal placode
intersection_of: UBERON:0005085 ! ectodermal placode
intersection_of: has_potential_to_develop_into UBERON:0000965 ! lens of camera-type eye
relationship: developmentally_induced_by UBERON:0004128 ! optic vesicle
relationship: has_potential_to_develop_into UBERON:0000965 ! lens of camera-type eye
relationship: part_of UBERON:0010312 {source="ZFA"} ! immature eye
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png" xsd:anyURI
property_value: UBPROP:0000001 "Ectodermal primordium of the lens of the eye. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000122", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The optic cup induces the overlying surface ectoderm first to thicken as a lens placode and then to invaginate and form a lens vesicle that differentiates into the lens.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000166", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "Classical transplantation experiments using amphibian embryos suggested that the optic vesicle is the source of lens-inducing signals sufficient to generate lens tissues in competent ectoderm (reviewed in Grainger et al., 1996). More recent findings suggest a multistep model for lens induction. There is now good evidence that lens specification occurs at the neurula stage, before the optic vesicle contact the surface ectoderm, and that neural crest cell migration in the frontonasal region is required to restrict the position of the lens placode (Bailey et al., 2006)" xsd:string {source="NCBIBook:NBK53175"}

[Term]
id: UBERON:0003074
name: mesonephric duct
namespace: uberon
def: "Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]." [https://github.com/obophenotype/uberon/issues/28, Wikipedia:Mesonephric_duct, ZFIN:curator]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "archinephric duct" RELATED [VHOG:0000082, Wikipedia:Wolffian_duct]
synonym: "ductus mesonephricus; ductus Wolffi" RELATED OMO:0003011 [Wikipedia:Mesonephric_duct]
synonym: "Leydig's duct" RELATED [Wikipedia:Wolffian_duct]
synonym: "renal duct" RELATED []
synonym: "Wolffian duct" EXACT [GOC:yaf, Wikipedia:Wolffian_duct, ZFA:0000546]
xref: AAO:0000637
xref: BTO:0005990 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: EHDAA2:0001243
xref: EHDAA:1590
xref: EMAPA:16577
xref: GAID:1315
xref: MESH:D014928
xref: NCIT:C26469
xref: SCTID:308800003
xref: TAO:0000546
xref: UMLS:C0043204 {source="ncithesaurus:Mesonephric_Duct"}
xref: VHOG:0000082
xref: Wikipedia:Mesonephric_duct
xref: XAO:0000242
xref: ZFA:0000546
is_a: UBERON:0000083 ! mesonephric tubule
is_a: UBERON:0009201 {source="GO"} ! nephric duct
relationship: develops_from UBERON:0003060 ! pronephric duct
relationship: develops_from UBERON:0005792 {source="EHDAA2"} ! nephric ridge
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png" xsd:anyURI
property_value: editor_note "Consider adding subclasses for male and female specific variants" xsd:string
property_value: editor_note "TODO - mesonephric portion of the nephric duct" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/rfoulger
property_value: UBPROP:0000001 "Anatomical structure consisting of either of a pair of longitudinal ducts which carry urine and in males, sperm, to the cloaca.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000637", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000001 "The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "(...) in all craniates, the archinephric duct develops in embryogeny.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.686", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "In the male the Wolffian duct persists, and forms for example the epididymis, the ductus deferens, the ejaculatory duct, seminal vesicle and efferent ducts." xsd:string

[Term]
id: UBERON:0003075
name: neural plate
namespace: uberon
def: "A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]." [ISBN:0815318960, OMD:neural+plate, Wikipedia:Neural_plate, ZFIN:curator]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "lamina neuralis" RELATED OMO:0003011 [Wikipedia:Neural_plate]
synonym: "presumptive central nervous system" RELATED []
xref: AAO:0011072
xref: BTO:0001765
xref: DHBA:10153
xref: DMBA:15565
xref: EHDAA:346
xref: EHDAA:902
xref: EMAPA:35593
xref: FMA:293879
xref: MESH:D054258 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C34225
xref: neuronames:1362
xref: RETIRED_EHDAA2:0001252
xref: TAO:0000132
xref: UMLS:C0920623 {source="ncithesaurus:Neural_Plate"}
xref: VHOG:0000068
xref: Wikipedia:Neural_plate
xref: XAO:0000249
xref: ZFA:0000132
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
is_a: UBERON:0016879 ! future central nervous system
relationship: developmentally_induced_by UBERON:0002328 {source="Wikipedia"} ! notochord
relationship: develops_from UBERON:0007284 ! presumptive neural plate
relationship: immediate_transformation_of UBERON:0007284 {source="Bgee:AN"} ! presumptive neural plate
relationship: only_in_taxon NCBITaxon:7711 {source="GOTAX:0000352"} ! Chordata
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png" xsd:anyURI
property_value: UBPROP:0000001 "The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000132", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000068", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003076
name: posterior neural tube
namespace: uberon
xref: AAO:0011082
xref: TAO:0007037
xref: VHOG:0001383
xref: XAO:0000250
xref: ZFA:0007037
is_a: UBERON:0002050 ! embryonic structure
disjoint_from: UBERON:0003080 {source="lexical"} ! anterior neural tube
relationship: develops_from UBERON:0003057 ! chordal neural plate
relationship: part_of UBERON:0001049 ! neural tube
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001383", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003077
name: paraxial mesoderm
namespace: uberon
def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]." [GO:0048339, https://github.com/obophenotype/uberon/issues/30]
subset: efo_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "mesoderma paraxiale" RELATED OMO:0003011 [Wikipedia:Paraxial_mesoderm]
synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255]
synonym: "somitic mesoderm" EXACT [ISBN:9780878932504]
xref: AAO:0010568
xref: EFO:0003515
xref: EMAPA:16183
xref: EMAPA:16751
xref: FMA:293145
xref: NCIT:C34244
xref: SCTID:361475002
xref: TAO:0000255
xref: UMLS:C1284009 {source="ncithesaurus:Paraxial_Mesoderm"}
xref: VHOG:0000114
xref: Wikipedia:Paraxial_mesoderm
xref: XAO:0000259
xref: ZFA:0000255
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue
is_a: UBERON:0015212 ! lateral structure
relationship: develops_from UBERON:0007285 ! presumptive paraxial mesoderm
relationship: existence_starts_during UBERON:0000109 ! gastrula stage
relationship: immediate_transformation_of UBERON:0007285 {source="Bgee:AN"} ! presumptive paraxial mesoderm
relationship: in_lateral_side_of UBERON:0000922 ! embryo
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI
property_value: UBPROP:0000001 "Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010568", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000114", ontology="VHOG", source="DOI:10.1002/dvdy.21177 Kusakabe R and Kuratani S. Evolutionary perspectives from development of mesodermal components in the lamprey. Developmental dynamics (2007)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "note that all AOs differ in the relationship between this structure and the mesoderm; in ZFA it is a subclass (and this is implied by the GO definition and GO relationships), in AAO it is part of, and in EHDAA2 it develops from the mesoderm (but in EHDAA2 the naming convention is to use 'paraxial mesenchyme', rather than 'paraxial mesoderm'). Also in ZFA it is part of the trunk whereas this conflicts with the division into head and trunk in ehdaa2 (which we follow here)" xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0003078
name: epibranchial placode
namespace: uberon
def: "Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia." [VHOG:0000117]
subset: efo_slim
synonym: "epibranchial placodes" EXACT OMO:0003004 [ZFA:0001294]
synonym: "ventrolateral placode" RELATED [ISBN:0471888893]
xref: AAO:0011036
xref: EFO:0003455
xref: FMA:293968
xref: TAO:0001294
xref: VHOG:0000117
xref: XAO:0000284
xref: ZFA:0001294
is_a: UBERON:0009955 {source="NCBIBook:NBK53175", source="ZFA"} ! neurogenic placode
relationship: develops_from UBERON:0000076 {source="EHDAA2-abduced"} ! external ectoderm
relationship: has_potential_to_developmentally_contribute_to UBERON:0002410 ! autonomic nervous system
relationship: part_of UBERON:0000010 {source="ZFA"} ! peripheral nervous system
property_value: UBPROP:0000001 "Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia. [Graham_A, The_development_and_evolution_of_the_pharyngeal_arches._J_Anat_(2001)_199:_133-141][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000117", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "These (the epibranchial placodes) are focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches in all vertebrates, and they produce the neuroblasts which migrate and condense to form the distal cranial ganglia: the geniculate, petrosal and nodose ganglia. (...) The one substantial difference between the vertebrate pharyngeal arches and those of the protochordates is the presence of the epibranchial placodes but the evolution of these structures was undoubtedly driven by the endoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000117", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A, The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "Epibranchial placodes-derived neurons innervate internal organs to transmit information such as heart rate, blood pressure, and visceral distension from the periphery to the central nervous system (Baker and Bronner-Fraser, 2001). From rostral to caudal the epibranchial placodes comprise the geniculate, petrosal, and nodose placodes, each associated in sequence with the first, second and third branchial clefts. Each placode contributes sensory neurons to cranial nerves VII (facial nerve), IX (glossopharyngeal nerve), and X (vagal nerve), respectively" xsd:string {source="NCBIBook:NBK53175"}
property_value: UBPROP:0000012 "in XAO this develops_from dorsolateral placode, but in NBK53175, this is a separate group" xsd:string {external_ontology="XAO"}

[Term]
id: UBERON:0003080
name: anterior neural tube
namespace: uberon
xref: AAO:0011012
xref: TAO:0007038
xref: VHOG:0001384
xref: XAO:0000307
xref: ZFA:0007038
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0003056 ! pre-chordal neural plate
relationship: part_of UBERON:0001049 ! neural tube
property_value: editor_note "TODO - add grouping class for the anterior end of the neural tube at all stages" xsd:string
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001384", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003081
name: lateral plate mesoderm
namespace: uberon
alt_id: UBERON:0006258
def: "Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]." [MP:0010117, Wikipedia:Lateral_plate_mesoderm]
subset: pheno_slim
subset: uberon_slim
synonym: "lateral mesoderm" EXACT [GO:0048368]
synonym: "lateral plate" RELATED []
synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919]
synonym: "LPM" EXACT OMO:0003000 [ZFA:0000121]
synonym: "mesoderma laminae lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_plate_mesoderm]
xref: AAO:0010574
xref: EHDAA2:0000919
xref: EHDAA:379
xref: EMAPA:16179
xref: FMA:293149
xref: NCIT:C34199
xref: SCTID:361477005
xref: TAO:0000121
xref: UMLS:C1517749 {source="ncithesaurus:Lateral_Mesoderm"}
xref: VHOG:0000118
xref: Wikipedia:Lateral_plate_mesoderm
xref: XAO:0000311
xref: ZFA:0000121
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
relationship: part_of UBERON:0000926 {source="EHDAA2", source="VHOG"} ! mesoderm
relationship: surrounds UBERON:0003887 ! intraembryonic coelom
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI
property_value: UBPROP:0000001 "Portion of mesoderm traditionally thought to give rise to limb bones and parts of the girdles.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010574", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "The portion of the mesoderm of the trunk of vertebrate embryos lying lateral to the intermediate mesoderm. [...] [It] subdivides into two plates: one dorsal, called the somatopleure, and one ventral, called the splanchnopleure. [Gastrulation:_From_cells_to_embryo_(2004)_Cold_Spring_Harbor, Glossary_XV, New_York:_Cold_Spring_Harbor_Laboratory_Press, Stern_CD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000118", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "A ventrolateral zone of amphioxus mesoderm grows down to surround the gut. Homology of this zone to the lateral plate mesoderm of vertebrates is supported by site of origin and fate.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000118", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "subclass of mesoderm in ZFA." xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0003082
name: myotome
namespace: uberon
def: "A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells." [AEO:0001018]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "muscle plate" RELATED []
synonym: "myomere" RELATED []
synonym: "myomeres" EXACT OMO:0003004 [TAO:0001056]
synonym: "myotome region" RELATED []
synonym: "myotomes" RELATED []
synonym: "myotomus" RELATED OMO:0003011 [Wikipedia:Myotome]
xref: AAO:0011067
xref: AEO:0001018
xref: BTO:0000742
xref: EHDAA2_RETIRED:0003431
xref: EHDAA:1721
xref: EHDAA:1727
xref: EHDAA:1733
xref: EHDAA:1739
xref: EMAPA:32841
xref: FMA:295658
xref: NCIT:C34214
xref: SCTID:344535001
xref: TAO:0001056
xref: UMLS:C1513802 {source="ncithesaurus:Myotome_Region"}
xref: VHOG:0001244
xref: Wikipedia:Myotome
xref: XAO:0000315
xref: ZFA:0001056
is_a: UBERON:0017650 {source="AEO"} ! developing mesenchymal structure
relationship: contributes_to_morphology_of UBERON:0001630 ! muscle organ
relationship: develops_from UBERON:0004290 {source="EHDAA2-abduced"} ! dermomyotome
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png" xsd:anyURI
property_value: editor_note "The term 'myotome' is also used to describe the muscles served by a single nerve root / spinal segment - consider adding new class, myomere." xsd:string
property_value: UBPROP:0000001 "Portion of the somites giving rise to body wall muscle masses. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001056", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "In all vertebrates, the skeletal muscle of the body axis is chiefly derived from an early embryonic compartment, known as the myotome.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001244", ontology="VHOG", source="DOI:10.1038/sj.embor.embor920 Hollway GE, Currie PD, Myotome meanderings. Cellular morphogenesis and the making of muscle. EMBO Rep.(2003)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003083
name: trunk neural crest
namespace: uberon
def: "Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]." [ISBN:0815318960, Wikipedia:Trunk_neural_crest]
subset: efo_slim
subset: uberon_slim
synonym: "TNC" EXACT OMO:0003000 [XAO:0000319]
synonym: "trunk crest" RELATED []
xref: AAO:0010582
xref: EFO:0003605
xref: EHDAA2:0001901
xref: TAO:0001024
xref: VHOG:0000062
xref: Wikipedia:Trunk_neural_crest
xref: XAO:0000319
xref: ZFA:0001024
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
relationship: has_part CL:0000011 {source="ZFA"} ! migratory trunk neural crest cell
relationship: part_of UBERON:0002342 ! neural crest
property_value: UBPROP:0000001 "Post-cranial portion of the neural crest. Exact anatomical derivations not experimentally resolved in amphibians.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010582", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000062", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003084
name: heart primordium
namespace: uberon
def: "Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone." [ZFIN:curator]
subset: uberon_slim
synonym: "cardiac field" RELATED [ZFA:0000028]
synonym: "fused heart primordium" RELATED []
xref: AAO:0011044
xref: BTO:0001887
xref: NCIT:C34276
xref: TAO:0000028
xref: UMLS:C1514450 {source="ncithesaurus:Primordium_of_the_Heart"}
xref: XAO:0000336
xref: ZFA:0000028
is_a: UBERON:0001048 {source="Obol"} ! primordium
relationship: develops_from UBERON:0003081 {source="ZFA"} ! lateral plate mesoderm
relationship: develops_from UBERON:0004140 ! primary heart field
relationship: develops_from UBERON:0007005 {source="XAO"} ! cardiogenic splanchnic mesoderm
relationship: part_of UBERON:0004535 {source="ZFA"} ! cardiovascular system
property_value: editor_note "should probably be merged with heart rudiment." xsd:string
property_value: UBPROP:0000001 "Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000028", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The fused aspects of ventral mesoderm, which have migrated from either side of the prechordal plate, and fused ventrally, just behind the cement gland. They will give rise to the endocardium at NF stage 27&28.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011044", ontology="AAO", source="XAO:curator"}
property_value: UBPROP:0000002 "relationship loss: develops_from lateral mesoderm (TAO:0001065)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000028", ontology="TAO"}

[Term]
id: UBERON:0003086
name: caudal artery
namespace: uberon
def: "Extension of the dorsal aorta in the tail." [Wikipedia:Caudal_artery, ZFIN:curator]
subset: efo_slim
subset: uberon_slim
synonym: "CA" RELATED []
xref: AAO:0011023
xref: EFO:0003472
xref: TAO:0000011
xref: VHOG:0000123
xref: Wikipedia:Caudal_artery
xref: XAO:0000364
xref: ZFA:0000011
is_a: UBERON:0001637 ! artery
is_a: UBERON:0003524 ! tail blood vessel
intersection_of: UBERON:0001637 ! artery
intersection_of: connecting_branch_of UBERON:0005805 ! dorsal aorta
intersection_of: part_of UBERON:0007812 ! post-anal tail
relationship: connecting_branch_of UBERON:0005805 ! dorsal aorta
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:2001073 ! axial vasculature
property_value: UBPROP:0000001 "Extension of the dorsal aorta in the tail. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000011", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The posterior extension of the dorsal aorta to the tail region, which degenerates at metamorphosis.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011023", ontology="AAO", source="ISBN:0-226-55763-4"}

[Term]
id: UBERON:0003089
name: sclerotome
namespace: uberon
def: "Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]." [https://github.com/obophenotype/uberon/issues/316, Wikipedia:Sclerotome, XB:curator]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "sclerotomes" EXACT OMO:0003004 [TAO:0001080]
synonym: "sclerotomus" RELATED OMO:0003011 [Wikipedia:Sclerotome]
xref: AAO:0010571
xref: AEO:0000212
xref: BTO:0006255 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: EHDAA2:0003439
xref: EMAPA:31159
xref: FMA:295652
xref: NCIT:C34287
xref: TAO:0001080
xref: UMLS:C0183176 {source="ncithesaurus:Sclerotome"}
xref: VHOG:0000680
xref: Wikipedia:Sclerotome
xref: XAO:0000397
xref: ZFA:0001080
is_a: UBERON:0005856 {source="EHDAA2"} ! developing mesenchymal condensation
is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population
relationship: develops_from UBERON:0002329 {source="ZFA"} ! somite
relationship: only_in_taxon NCBITaxon:7742 {source="VHOG:0000680"} ! Vertebrata <vertebrates>
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png" xsd:anyURI
property_value: UBPROP:0000001 "Skeletogenic portion of somites.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010571", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000680", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "part_of somite in XAO" xsd:string {external_ontology="XAO"}

[Term]
id: UBERON:0003099
name: cranial neural crest
namespace: uberon
def: "Neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage." [MGI:anna]
subset: efo_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "cephalic neural crest" EXACT [EMAPA:16091]
synonym: "CNC" EXACT OMO:0003000 [XAO:0001001]
synonym: "cranial NCC population" EXACT []
synonym: "crista neuralis cranialis" RELATED OMO:0003011 [Wikipedia:Cranial_neural_crest]
synonym: "head crest" RELATED []
synonym: "head NCC population" EXACT []
synonym: "head neural crest" RELATED []
xref: AAO:0010580
xref: EFO:0003645
xref: EHDAA2:0004420
xref: EMAPA:16091
xref: TAO:0001194
xref: VHOG:0000063
xref: Wikipedia:Cranial_neural_crest
xref: XAO:0001001
xref: ZFA:0001194
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
relationship: has_part CL:0000008 ! migratory cranial neural crest cell
relationship: part_of UBERON:0002342 ! neural crest
property_value: UBPROP:0000001 "Anterior most portion of the neural crest. Migrates in three highly conserved streams: mandibular, hyoid and branchial.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010580", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "Neural crest that is part of the head.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001194", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000063", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003100
name: female organism
namespace: uberon
def: "Gonochoristic organism that can produce female gametes." [CARO:0000028]
subset: pheno_slim
subset: vertebrate_core
synonym: "female" RELATED [TAO:0000303]
synonym: "female human body" NARROW SENSU [FMA:67812]
xref: AAO:0010030
xref: BILA:0000028
xref: CARO:0000028
xref: FBbt:00007011 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:67812
xref: HAO:0000028
xref: SCTID:362608006
xref: TAO:0000303
xref: TGMA:0001839
xref: XAO:0003005
xref: ZFA:0000303
is_a: UBERON:0000468 ! multicellular organism
disjoint_from: UBERON:0003101 ! male organism
property_value: RO:0002171 UBERON:0003101

[Term]
id: UBERON:0003101
name: male organism
namespace: uberon
def: "Gonochoristic organism that can produce male gametes." [CARO:0000027]
subset: pheno_slim
subset: vertebrate_core
synonym: "male" RELATED [TAO:0000242]
synonym: "male human body" NARROW SENSU [FMA:67811]
xref: AAO:0010033
xref: BILA:0000027
xref: CARO:0000027
xref: FBbt:00007004 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:67811
xref: HAO:0000027
xref: SCTID:362609003
xref: TAO:0000242
xref: TGMA:0001838
xref: WBbt:0007850
xref: XAO:0003006
xref: ZFA:0000242
is_a: UBERON:0000468 ! multicellular organism

[Term]
id: UBERON:0003102
name: surface structure
namespace: uberon
def: "Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/24]
subset: upper_level
synonym: "anatomical surface feature" EXACT [EHDAA2:0003010]
synonym: "surface feature" RELATED []
synonym: "surface region" RELATED []
synonym: "surface structures" RELATED OMO:0003004 [ZFA:0000292]
xref: AAO:0010337
xref: AEO_RETIRED:0000010
xref: EHDAA2_RETIRED:0003010
xref: galen:SurfaceRegion
xref: TAO:0000292
xref: VSAO:0000001
xref: Wikipedia:Surface_structure
xref: XAO:0003028
xref: ZFA:0000292
is_a: UBERON:0000061 ! anatomical structure
relationship: adjacent_to UBERON:0013514 ! space surrounding organism
property_value: editor_note "consider obsoleting. See issue/1305" xsd:string
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul
property_value: UBPROP:0000001 "Organism subdivision which is the collection of anatomical structures on the body surface.[ZFA]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000292", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0003103
name: compound organ
namespace: uberon
def: "Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types." [CARO:0000024]
subset: organ_slim
subset: upper_level
synonym: "organ" RELATED []
xref: AAO:0010015
xref: AEO:0000024
xref: BILA:0000024
xref: CARO:0000024
xref: EHDAA2:0003024
xref: HAO:0000024
xref: TADS:0000598
xref: TAO:0000496
xref: TGMA:0001837
xref: VHOG:0001723
xref: XAO:0003041
xref: ZFA:0000496
is_a: UBERON:0000062 ! organ
property_value: curator_notes "this class was introduced for consistency with CARO. However, in this ontology we typically classify organs directly under 'organ' rather than subdividing into compound and simple organs" xsd:string

[Term]
id: UBERON:0003104
name: mesenchyme
namespace: uberon
def: "Portion of tissue composed of mesenchymal cells (motile cells that develop from epthelia via an epithelial to mesenchymal transition) and surrounding extracellular material. Mesenchyme has different embryological origins in different metazoan taxa - in many invertebrates it derives in whole or part from ectoderm. In vertebrates it derives largely from mesoderm, and sometimes the terms are used interchangeably, e.g. lateral plate mesoderm/mesenchyme." [https://archive.org/details/invertebratesnde00brus/page/n240/mode/2up, https://en.wikipedia.org/wiki/Mesenchyme, https://github.com/obophenotype/uberon/issues/1641]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "mesenchyma" RELATED OMO:0003011 [Wikipedia:Mesenchyme]
synonym: "mesenchymal tissue" EXACT []
synonym: "mesenchyme tissue" EXACT []
synonym: "portion of mesenchymal tissue" EXACT []
synonym: "portion of mesenchyme tissue" EXACT []
xref: AAO:0010427
xref: AEO:0000145
xref: BTO:0001393
xref: CALOHA:TS-0620
xref: EHDAA2:0003145
xref: EV:0100007
xref: NCIT:C13301
xref: TAO:0000393
xref: UMLS:C0162415 {source="ncithesaurus:Mesenchyme"}
xref: VHOG:0000170
xref: Wikipedia:Mesenchyme
xref: XAO:0003046
xref: ZFA:0000393
is_a: UBERON:0000479 ! tissue
intersection_of: UBERON:0000479 ! tissue
intersection_of: composed_primarily_of CL:0008019 ! mesenchymal cell
relationship: composed_primarily_of CL:0008019 ! mesenchymal cell
relationship: functionally_related_to GO:0032502 ! developmental process
relationship: has_developmental_contribution_from UBERON:0000926 {gci_relation="part_of", gci_filler="NCBITaxon:7711"} ! mesoderm
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f4/Mesenchymal_Stem_Cell.jpg" xsd:anyURI
property_value: editor_note "the relationship to mesoderm is weaker than develops_from in order to have classes such as 'head mesenchyme from mesoderm' make sense" xsd:string
property_value: UBPROP:0000001 "A mesh-like cell arrangement, less compact than an epithelium. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000393", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Portion of tissue consisting of loosely organized undifferentiated mesodermal cells that give rise to such structures as connective tissues, blood, lymphatics, bone, and cartilage.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010427", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000007 "mesenchymal" xsd:string

[Term]
id: UBERON:0003112
name: olfactory region
namespace: uberon
def: "Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the olfactory organ." [TAO:0000351]
subset: efo_slim
synonym: "ethmoid region" RELATED [ZFA:0000351]
xref: AAO:0010206
xref: EFO:0003525
xref: NCIT:C98765
xref: TAO:0000351
xref: XAO:0003172
xref: ZFA:0000351
is_a: UBERON:0034921 ! multi organ part structure
relationship: part_of UBERON:0001703 ! neurocranium
relationship: part_of UBERON:0002241 ! chondrocranium
property_value: UBPROP:0000001 "Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the peripheral olfactory organ.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000351", ontology="TAO", source="TAO:MAH"}
property_value: UBPROP:0000001 "Anatomical cluster that is located in the anterior region of the neurocranium and provides structural support for the olfactory organs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010206", ontology="AAO", source="AAO:EJS"}

[Term]
id: UBERON:0003113
name: dermatocranium
namespace: uberon
def: "Subdivision of skeleton that includes all dermal bones in the cranial skeleton[ZFA,modified]." [Wikipedia:Skull_roof, ZFA:0000863]
synonym: "dendrocranium" EXACT [TAO:0000863]
synonym: "dermal bone cranium" RELATED [ZFA:0000863]
synonym: "dermal part of skull" RELATED []
synonym: "dermal skull bones" RELATED []
synonym: "dermal skull roof" NARROW [PMID:11523816, Wikipedia:Skull_roof]
synonym: "dermatocranial cover" NARROW []
synonym: "exocranium" EXACT [UBERONREF:0000007]
synonym: "roof of skull" NARROW [Wikipedia:Skull_roof]
synonym: "roofing bones of the skull" RELATED [Wikipedia:Skull_roof]
synonym: "skull exoskeleton" RELATED []
synonym: "skull roof" NARROW [PMID:11523816, Wikipedia:Skull_roof]
xref: AAO:0010154
xref: TAO:0000863
xref: VHOG:0001665
xref: Wikipedia:Skull_roof
xref: XAO:0003169
xref: ZFA:0000863
is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0010364 ! dermal skeleton
property_value: editor_note "wikipedia treats skull roof and dermatocranium as synonymous, but some sources treat the roof as being part of the dermatocranium - see UBERONREF:0000007" xsd:string
property_value: RO:0002161 NCBITaxon:7777 {source="ISBN:0073040584"}
property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium and composed of dermally derived bones.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000863", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium which consists of dermally derived bones.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010154", ontology="AAO", source="AAO:BJB"}

[Term]
id: UBERON:0003115
name: pharyngeal arch 4
namespace: uberon
def: "Contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus." [MP:0006340]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "4th arch" RELATED [EHDAA2:0000086]
synonym: "4th branchial arch" EXACT SENSU []
synonym: "4th pharyngeal arch" EXACT []
synonym: "4th visceral arch" EXACT []
synonym: "branchial arch 2" RELATED SENSU [AAO:0010366, ZFA:0001607]
synonym: "fourth pharyngeal arch" EXACT []
synonym: "fourth visceral arch" RELATED [VHOG:0000299]
synonym: "gill arch 2" EXACT SENSU [ZFA:0001607]
synonym: "second branchial arch" RELATED SENSU [ZFA:0001607]
synonym: "second gill arch" EXACT SENSU [ZFA:0001607]
synonym: "visceral arch 4" EXACT []
xref: AAO:0010366
xref: EHDAA2:0000086
xref: EHDAA:1663
xref: EMAPA:16760
xref: FMA:293035
xref: SCTID:308770007
xref: TAO:0001599
xref: VHOG:0000299
xref: XAO:0000449
xref: ZFA:0001607
is_a: UBERON:0002539 ! pharyngeal arch
property_value: UBPROP:0000001 "The second pharyngeal/branchial arch; arises as a thickening of the pharygeal wall between the first and second branchial clefts; contains the second aortic arch; forms part of the hyoid bone, tongue and facial musculature.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010366", ontology="AAO", source="ISBN:0-02-377110-0"}
property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000299", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M and Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "in XAO, called branchial arch 2 and df VP4" xsd:string {external_ontology="XAO"}
property_value: UBPROP:0000103 "4" xsd:nonNegativeInteger

[Term]
id: UBERON:0003117
name: pharyngeal arch 6
namespace: uberon
alt_id: UBERON:0004349
def: "The 6th pharyngeal arch. contributes to the development of the sternocleidomastoid and trapezius muscles." [MP:0006347]
subset: pheno_slim
synonym: "6th arch" EXACT [EHDAA2:0004075]
synonym: "6th pharyngeal arch" RELATED [VHOG:0001205]
synonym: "6th visceral arch" RELATED [VHOG:0001205]
synonym: "branchial arch 4" RELATED SENSU [AAO:0010368, ZFA:0001609]
synonym: "fourth branchial arch" RELATED SENSU []
synonym: "gill arch 4" EXACT [ZFA:0001609]
synonym: "sixth branchial arch" EXACT []
synonym: "sixth pharyngeal arch" RELATED [VHOG:0001205]
synonym: "sixth visceral arch" RELATED [XAO:0000453]
synonym: "visceral arch 6" EXACT [ZFA:0001609]
xref: AAO:0010368
xref: EHDAA2:0004075
xref: EMAPA:32766
xref: FMA:293047
xref: SCTID:308772004
xref: TAO:0001601
xref: VHOG:0001205
xref: XAO:0000453
xref: ZFA:0001609
is_a: UBERON:0002539 ! pharyngeal arch
property_value: UBPROP:0000001 "The forth in a series of paired bars in the wall of the pharynx, within which are formed the forth aortic arch and the cartilage bar of the visceral skeleton, forms and supports the gills.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010368", ontology="AAO", source="ISBN:0-02-377110-0"}
property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001205", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M, Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000103 "6" xsd:nonNegativeInteger

[Term]
id: UBERON:0003118
name: pharyngeal arch artery 1
namespace: uberon
alt_id: UBERON:0004371
def: "The vessels formed within the first pair of branchial arches in embryogenesis." [MP:0010355]
subset: pheno_slim
subset: vertebrate_core
synonym: "1st aortic arch artery" RELATED [EMAPA:16685]
synonym: "1st arch artery" EXACT [EMAPA:16685]
synonym: "1st branchial arch artery" RELATED [EMAPA:16685]
synonym: "1st pharyngeal arch artery" RELATED [EMAPA:16685]
synonym: "AA1" EXACT [ZFA:0005005]
synonym: "aortic arch 1" EXACT [ZFA:0005005]
synonym: "first aortic arch" EXACT [XAO:0000342]
synonym: "first arch artery" RELATED [EMAPA:16685]
synonym: "first branchial arch artery" EXACT []
synonym: "mandibular aortic arch" EXACT [ZFA:0005005]
xref: AAO:0010415
xref: EHDAA2:0000007
xref: EMAPA:16202
xref: EMAPA:16685
xref: SCTID:308774003
xref: TAO:0005005
xref: VHOG:0000149
xref: XAO:0000342
xref: ZFA:0005005
is_a: UBERON:0004363 ! pharyngeal arch artery
intersection_of: UBERON:0004363 ! pharyngeal arch artery
intersection_of: part_of UBERON:0004362 ! pharyngeal arch 1
relationship: contributes_to_morphology_of UBERON:0004362 ! pharyngeal arch 1
relationship: part_of UBERON:0004362 ! pharyngeal arch 1
property_value: UBPROP:0000008 "Disappears early in development in tetrapods" xsd:string
property_value: UBPROP:0000012 "ZFA states that The paired aortic arch 1 arteries branch off of the ventral aorta, and empty into the right and left lateral dorsal aortas" xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0003121
name: pharyngeal arch artery 4
namespace: uberon
alt_id: UBERON:0004350
def: "The vessels formed within the fourth pair of branchial arches in embryogenesis." [MP:0006354]
comment: proximal right subclavian
subset: pheno_slim
subset: vertebrate_core
synonym: "4th aortic arch artery" RELATED [EMAPA:17004]
synonym: "4th arch artery" EXACT [EHDAA2:0000087]
synonym: "4th branchial arch artery" RELATED [EMAPA:17004]
synonym: "4th pharyngeal arch artery" RELATED [EMAPA:17004]
synonym: "AA4" EXACT [ZFA:0005008]
synonym: "aortic arch 4" EXACT [ZFA:0005008]
synonym: "fourth aortic arch" EXACT [XAO:0000355]
synonym: "fourth branchial arch artery" EXACT []
synonym: "systemic arch" RELATED [ISBN:0073040584, XAO:0000355]
xref: AAO:0010420
xref: EHDAA2:0000087
xref: EMAPA:17004
xref: SCTID:308777005
xref: TAO:0005008
xref: Wikipedia:Aortic_arches#Arch_4
xref: XAO:0000355
xref: ZFA:0005008
is_a: UBERON:0004363 ! pharyngeal arch artery
intersection_of: UBERON:0004363 ! pharyngeal arch artery
intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4
relationship: part_of UBERON:0003115 ! pharyngeal arch 4
property_value: UBPROP:0000001 "Aortic arches 3 and 4 are not remodeled but are retained largely intact as the branchial arteries providing circulation through the gills. These areches are direct branches from the ventral aorta to the lateral dorsal aorta. Isogai et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005008", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The forth in a series paired arterial connections between the dorsal and ventral aortae, lies within the 4th branchial arch. The paired aortic arch 4 arteries branch directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010420", ontology="AAO", source="ISBN:0-02-377110-0"}
property_value: UBPROP:0000001 "The fourth right arch forms the right subclavian as far as the origin of its internal mammary branch; while the fourth left arch constitutes the arch of the aorta between the origin of the left carotid artery and the termination of the ductus arteriosus[WP][Wikipedia:Aortic_arches#Arch_4]." xsd:string {source="Wikipedia:Aortic_arches#Arch_4"}
property_value: UBPROP:0000011 "Normally, the left fourth arch becomes the aortic arch, the right fourth arch contributes to the innominate artery[http://emedicine.medscape.com/article/899609-overview] in birds it is the right fourth arch which forms the permanent aorta" xsd:string

[Term]
id: UBERON:0003123
name: pharyngeal arch artery 6
namespace: uberon
alt_id: UBERON:0004351
def: "The vessels formed within the sixth pair of branchial arches in embryogenesis." [MP:0006355]
subset: pheno_slim
subset: vertebrate_core
synonym: "6th aortic arch artery" RELATED [EMAPA:17005]
synonym: "6th arch artery" EXACT [EMAPA:17005]
synonym: "6th branchial arch artery" RELATED [EMAPA:17005]
synonym: "6th pharyngeal arch artery" RELATED [EMAPA:17005]
synonym: "AA6" EXACT [ZFA:0005016]
synonym: "aortic arch 6" EXACT [ZFA:0005016]
synonym: "pulmonary arch" RELATED [ISBN:0073040584]
synonym: "sixth aortic arch" EXACT [XAO:0000353]
synonym: "sixth branchial arch artery" EXACT []
xref: AAO:0010422
xref: EHDAA2:0000102
xref: EMAPA:17005
xref: SCTID:308779008
xref: TAO:0005016
xref: VHOG:0000144
xref: Wikipedia:Aortic_arches#Arch_6
xref: XAO:0000353
xref: ZFA:0005016
is_a: UBERON:0004363 ! pharyngeal arch artery
intersection_of: UBERON:0004363 ! pharyngeal arch artery
intersection_of: part_of UBERON:0003117 ! pharyngeal arch 6
relationship: part_of UBERON:0003117 ! pharyngeal arch 6
property_value: UBPROP:0000001 "The fifth and sixth arches, which come on-line at approximately 2.5 dpf, have a common trunk from the ventral aorta and drain to the midline dorsal aorta via an independent route. The fifth and sixth aortic arches supply the trunk and tail with oxigenated blood. Isogai et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005016", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The sixth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 6 artery is paired and has a common trunk with aortic arch 5 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. It forms part of the pulmonary arteries, and in the later embryo, the ductus arteriosis. Aortic arches 5 and 6 together supply the trunk and tail with oxygenated blood.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010422", ontology="AAO", source="ISBN:0-02-377110-0"}
property_value: UBPROP:0000001 "The sixth right arch disappears; the sixth left arch gives off the pulmonary arteries and forms the ductus arteriosus; this duct remains pervious during the whole of fetal life, but then closes within the first few days after birth due to increased O2 concentration. Oxygen concentration causes the production of bradykinin which causes the ductus to constrict occluding all flow. Within 1-3 months, the ductus is obliterated and becomes the ligamentum arteriosus. His showed that in the early embryo the right and left arches each gives a branch to the lungs, but that later both pulmonary arteries take origin from the left arch[WP][Wikipedia:Aortic_arches#Arch_6]." xsd:string {source="Wikipedia:Aortic_arches#Arch_6"}
property_value: UBPROP:0000011 "the distal left sixth arch becomes the ductus arteriosus, the proximal sixth arches bilaterally contribute to the proximal branch pulmonary arteries" xsd:string {source="http://emedicine.medscape.com/article/899609-overview"}

[Term]
id: UBERON:0003124
name: chorion membrane
namespace: uberon
def: "The outermost extraembryonic membrane of amniotes." [http://orcid.org/0000-0002-6601-2165, https://github.com/geneontology/go-ontology/issues/22603, MESH:A10.615.284.473, MP:0002836]
comment: This term refers to the amniote structure. It is distinct from the concept of chorion in insects
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "chorion" EXACT []
synonym: "chorion (vertebrates)" EXACT []
synonym: "chorion frondosum" RELATED [Wikipedia:Chorion]
synonym: "chorionic sac" RELATED [Wikipedia:Chorion]
synonym: "embryonic chorion" EXACT []
synonym: "fetal chorion" EXACT []
synonym: "uterine chorion" EXACT [http://orcid.org/0000-0002-6601-2165, ZFIN:curator]
xref: BTO:0000252
xref: CALOHA:TS-0144
xref: EFO:0002780
xref: EHDAA2:0000245
xref: EHDAA:150
xref: EMAPA:16112
xref: EV:0100121
xref: FMA:80224
xref: GAID:1299
xref: MESH:D002823
xref: NCIT:C34122
xref: NCIT:C34124
xref: UMLS:C0008503 {source="ncithesaurus:Chorion"}
xref: UMLS:C1516505 {source="ncithesaurus:Chorionic_Sac"}
xref: VHOG:0000200
xref: Wikipedia:Chorion
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005631 ! extraembryonic membrane
relationship: adjacent_to UBERON:0000922 ! embryo
relationship: develops_from UBERON:0005971 {source="ISBN:0073040584"} ! amniotic fold
relationship: has_part UBERON:0003265 ! chorionic mesenchyme
relationship: has_part UBERON:0003374 ! chorionic ectoderm
relationship: only_in_taxon NCBITaxon:32524 {source="Hymans"} ! Amniota
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/51/Gray24.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The outer membrane enclosing the embryo in reptiles, birds, and mammals. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000200", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/chorion"}
property_value: UBPROP:0000001 "The outer membrane of the two membranes enclosing the embryo in reptiles, birds, and mammals. In placental mammals it contributes to the development of the placenta[BTO:0000252]." xsd:string {source="BTO:0000252"}
property_value: UBPROP:0000003 "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000200", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.187", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "chorionic" xsd:string
property_value: UBPROP:0000008 "The chorion of placentals is bilaminar as in reptiles and birds, but forms from the trophoblast and includes the ajdacent mesodermal layer [ISBN:0073040584]" xsd:string
property_value: UBPROP:0000011 "Extra-embryonic ectoderm" xsd:string {source="PMID:19829370"}

[Term]
id: UBERON:0003128
name: cranium
namespace: uberon
def: "Upper portion of the skull that excludes the mandible (when present in the organism)." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Cranium_(anatomy)]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "bones of cranium" EXACT [FMA:71325]
synonym: "calvarium" RELATED [BTO:0001328]
synonym: "epicranial plate" RELATED []
synonym: "ossa cranii" EXACT OMO:0003011 [FMA:71325, FMA:TA]
synonym: "set of bones of cranium" EXACT [FMA:71325]
synonym: "skeletal system of head" RELATED []
synonym: "skull minus mandible" EXACT []
synonym: "upper part of skull" EXACT []
xref: BTO:0001328
xref: EFO:0000831
xref: EHDAA:6029
xref: EMAPA:17680
xref: FMA:71325
xref: MA:0000316
xref: MAT:0000340
xref: MESH:D012886 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: MIAA:0000340
xref: SCTID:181889008
xref: VHOG:0000334
xref: Wikipedia:Cranium_(anatomy)
is_a: UBERON:0000075 {source="FMA-inferred"} ! subdivision of skeletal system
property_value: RO:0002171 UBERON:0003278
property_value: RO:0002175 NCBITaxon:7762
property_value: UBPROP:0000007 "cranial" xsd:string
property_value: UBPROP:0000012 "the inclusion of the FMA class here is probably not quite correct, as this class includes as parts sutures, whereas this is not part of the bones of the cranium" xsd:string {external_ontology="FMA"}
property_value: UBPROP:0000013 "The term cranium can be ambiguous, in that it can refer to the neurocranium, or the neurocranium and the Facial skeleton" xsd:string {source="WP"}

[Term]
id: UBERON:0003129
name: skull
namespace: uberon
def: "Anatomical structure that is part of the head consisting entirely of cranium and mandible[WP]." [http://sourceforge.net/tracker/?func=detail&aid=2962656&group_id=76834&atid=1205376, PMID:11523816, Wikipedia:Skull]
subset: pheno_slim
subset: uberon_slim
synonym: "cranial skeleton" RELATED []
synonym: "skeletal system of head" RELATED []
xref: BTO:0001295
xref: CALOHA:TS-2344
xref: EHDAA2:0000325
xref: EMAPA:17680
xref: FMA:46565
xref: GAID:82
xref: galen:Skull
xref: MESH:D012886
xref: NCIT:C12789
xref: SCTID:110530005
xref: UMLS:C0037303 {source="ncithesaurus:Skull"}
xref: Wikipedia:Skull
xref: WikipediaCategory:Skull
is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
relationship: has_part UBERON:0003128 ! cranium
relationship: has_part UBERON:0003278 ! skeleton of lower jaw
relationship: only_in_taxon NCBITaxon:89593 ! Craniata <chordates>
relationship: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0010323 ! cranial skeletal system
property_value: UBPROP:0000012 "in FMA the skull is divided into orbit, neurocranium (8 parts), viscerocranium (26 parts). Here we have a separate overlapping division into cranium and mandible." xsd:string {external_ontology="FMA"}
property_value: UBPROP:0000012 "in many ontologies, the structure called the cranium is inclusive of the mandible/lower jaw skeleton" xsd:string
property_value: UBPROP:0000013 "A skull that is missing a mandible is only a cranium; this is the source of a very commonly made error in terminology. Those animals having skulls are called craniates" xsd:string {source="WP"}

[Term]
id: UBERON:0003133
name: reproductive organ
namespace: uberon
def: "An organ involved in reproduction." [UBERON:xp]
subset: functional_classification
subset: organ_slim
subset: pheno_slim
synonym: "genital organ" EXACT []
synonym: "genitalia" RELATED OMO:0003004 []
synonym: "reproductive system organ" EXACT []
synonym: "sex organ" EXACT []
xref: EMAPA:17381
xref: EMAPA:37731 {source="MA:th"}
xref: MA:0001752
xref: MESH:D005835
xref: NCIT:C25177
xref: SCTID:128181006
xref: TGMA:0000591
xref: UMLS:C0017420 {source="ncithesaurus:Genitalia"}
xref: WBbt:0008422
is_a: UBERON:0000062 ! organ
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000062 ! organ
intersection_of: capable_of_part_of GO:0000003 ! reproduction
relationship: capable_of_part_of GO:0000003 ! reproduction
property_value: UBPROP:0000012 "GO uses genitalia for the singular organ" xsd:string {external_ontology="GO"}

[Term]
id: UBERON:0003134
name: female reproductive organ
namespace: uberon
def: "A female organ involved in reproduction." [UBERON:xp]
subset: organ_slim
subset: pheno_slim
synonym: "female organism reproductive organ" EXACT [OBOL:automatic]
synonym: "female organism reproductive structure" EXACT [OBOL:automatic]
synonym: "female organism reproductive system organ" EXACT [OBOL:automatic]
synonym: "female organism sex organ" EXACT [OBOL:automatic]
synonym: "female reproductive gland/organ" EXACT [MA:0000544]
synonym: "female reproductive system organ" EXACT []
synonym: "female sex organ" EXACT []
synonym: "reproductive organ of female organism" EXACT [OBOL:automatic]
synonym: "reproductive structure of female organism" EXACT [OBOL:automatic]
synonym: "reproductive system organ of female organism" EXACT [OBOL:automatic]
synonym: "sex organ of female organism" EXACT [OBOL:automatic]
xref: EMAPA:28540
xref: MA:0000544
is_a: UBERON:0003133 ! reproductive organ
intersection_of: UBERON:0003133 ! reproductive organ
intersection_of: part_of UBERON:0003100 ! female organism
relationship: part_of UBERON:0000474 ! female reproductive system

[Term]
id: UBERON:0003135
name: male reproductive organ
namespace: uberon
def: "A male organ involved in reproduction." [UBERON:xp]
subset: organ_slim
subset: pheno_slim
synonym: "male genital" RELATED [WBbt:0008423]
synonym: "male organism reproductive organ" EXACT [OBOL:automatic]
synonym: "male organism reproductive structure" EXACT [OBOL:automatic]
synonym: "male organism reproductive system organ" EXACT [OBOL:automatic]
synonym: "male organism sex organ" EXACT [OBOL:automatic]
synonym: "male reproductive gland/organ" EXACT [MA:0000545]
synonym: "male reproductive system organ" EXACT []
synonym: "male sex organ" EXACT []
synonym: "reproductive organ of male organism" EXACT [OBOL:automatic]
synonym: "reproductive structure of male organism" EXACT [OBOL:automatic]
synonym: "reproductive system organ of male organism" EXACT [OBOL:automatic]
synonym: "sex organ of male organism" EXACT [OBOL:automatic]
xref: MA:0000545
xref: WBbt:0008423
is_a: UBERON:0003133 ! reproductive organ
intersection_of: UBERON:0003133 ! reproductive organ
intersection_of: part_of UBERON:0003101 ! male organism
relationship: part_of UBERON:0000079 ! male reproductive system

[Term]
id: UBERON:0003218
name: ovary septum
namespace: uberon
def: "Septum that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)[GO]." [GO:0080126]
is_a: UBERON:0003037 ! septum
intersection_of: UBERON:0003037 ! septum
intersection_of: part_of UBERON:0000992 ! ovary
relationship: part_of UBERON:0000992 ! ovary

[Term]
id: UBERON:0003220
name: metanephric mesenchyme
namespace: uberon
def: "One of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO]." [GO:0072075, Wikipedia:Metanephric_blastema]
comment: Genes: The positional specification of the metanephrogenic mesenchyme is negatively regulated by Foxc1 and Foxc2. Next the permanent kidney forming metanephrogenic mesenchyme is specified by Hox11 genes. The competence to respond to ureteric bud inducers is regulated by WT1. GDNF secretion restricted to posterior region by Robo2 and Sprouty1. The receptors for GDNF are synthesized in the nephric ducts and later in ureteric buds [ISBN:9780878932504 "Developmental Biology"]
subset: pheno_slim
synonym: "metanephric blastema" EXACT [Wikipedia:Metanephric_blastema]
synonym: "metanephric mesoderm" EXACT [Wikipedia:Metanephric_blastema]
synonym: "metanephrogenic mesenchyme" EXACT [EHDAA:5021]
synonym: "metanephros associated mesenchyme" EXACT [RETIRED_EHDAA2:0001139]
xref: EHDAA2:0004062
xref: EHDAA:4041
xref: EHDAA:5021
xref: EHDAA:5915
xref: EMAPA:17375
xref: SCTID:361529008
xref: VHOG:0000540
xref: Wikipedia:Metanephric_blastema
is_a: UBERON:0003918 ! kidney mesenchyme
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: has_potential_to_develop_into UBERON:0000081 ! metanephros
relationship: developmentally_induced_by UBERON:0000084 {source="ISBN:9780878932504"} ! ureteric bud
relationship: develops_from UBERON:0003074 ! mesonephric duct
relationship: has_potential_to_develop_into UBERON:0000081 ! metanephros
property_value: UBPROP:0000001 "A mass of intermediate mesodermal cells around the distal end of the ureteric bud that gives rise to nephrons in the metanephric kidney. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000540", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/metanephric+mesenchyme"}
property_value: UBPROP:0000003 "When the ureteric buds emerge from the nephric duct, they enter the metanephrogenic mesenchyme. The ureteric buds induce this mesenchymal tissue to condense around them and differentiate into the nephrons of the mammalian kidney. As this mesenchyme differentiates, it tells the ureteric bud to branch and grow.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000540", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) p.462", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003224
name: chorion syncytiotrophoblast
namespace: uberon
def: "An extraembryonic structure that develops_from a syncytiotrophoblast and is part of a chorion." [OBOL:automatic]
xref: EHDAA2:0001973
xref: EHDAA:156
is_a: UBERON:0000478 ! extraembryonic structure
intersection_of: UBERON:0000478 ! extraembryonic structure
intersection_of: develops_from UBERON:0000371 ! syncytiotrophoblast
intersection_of: part_of UBERON:0003124 ! chorion membrane
relationship: develops_from UBERON:0000371 {notes="polar trophectoderm syncytiotrophoblast", source="EHDAA2"} ! syncytiotrophoblast
relationship: part_of UBERON:0003124 {source="EHDAA2"} ! chorion membrane
property_value: editor_note "TODO - check" xsd:string

[Term]
id: UBERON:0003235
name: epithelium of upper jaw
namespace: uberon
def: "An epithelium that is part of a upper jaw [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of palatoquadrate arch" EXACT [OBOL:automatic]
synonym: "epithelial tissue of upper jaw" EXACT [OBOL:automatic]
synonym: "epithelium of palatoquadrate arch" EXACT [OBOL:automatic]
synonym: "palatoquadrate arch epithelial tissue" EXACT [OBOL:automatic]
synonym: "palatoquadrate arch epithelium" EXACT [OBOL:automatic]
synonym: "upper jaw epithelial tissue" EXACT [OBOL:automatic]
synonym: "upper jaw epithelium" EXACT [OBOL:automatic]
xref: EHDAA2:0002119
xref: EHDAA:8027
xref: EMAPA:17943
xref: EMAPA:18971
is_a: UBERON:0035037 ! jaw epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001709 ! upper jaw region
relationship: part_of UBERON:0001709 ! upper jaw region

[Term]
id: UBERON:0003236
name: epithelium of lower jaw
namespace: uberon
def: "An epithelium that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of lower jaw" EXACT [OBOL:automatic]
synonym: "epithelial tissue of ventral mandibular arch" EXACT [OBOL:automatic]
synonym: "epithelium of ventral mandibular arch" EXACT [OBOL:automatic]
synonym: "lower jaw epithelial tissue" EXACT [OBOL:automatic]
synonym: "lower jaw epithelium" EXACT [OBOL:automatic]
synonym: "ventral mandibular arch epithelial tissue" EXACT [OBOL:automatic]
synonym: "ventral mandibular arch epithelium" EXACT [OBOL:automatic]
xref: EHDAA2:0001019
xref: EHDAA:7999
xref: EMAPA:35516
xref: VHOG:0000802
is_a: UBERON:0035037 ! jaw epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001710 ! lower jaw region
relationship: part_of UBERON:0001710 ! lower jaw region

[Term]
id: UBERON:0003257
name: yolk sac endoderm
namespace: uberon
def: "The portion of the yolk sac that is derived from endoderm and lines the yolk sac." [UBERON:cjm]
xref: EHDAA2:0002215
xref: EHDAA:166
xref: EMAPA:16086
xref: VHOG:0000626
is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure
is_a: UBERON:0005292 ! extraembryonic tissue
is_a: UBERON:0005911 ! endo-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: bounding_layer_of UBERON:0001040 ! yolk sac
intersection_of: develops_from UBERON:0000925 ! endoderm
relationship: bounding_layer_of UBERON:0001040 ! yolk sac
relationship: part_of UBERON:0001040 ! yolk sac

[Term]
id: UBERON:0003258
name: endoderm of foregut
namespace: uberon
def: "An endoderm that is part of a foregut [Automatically generated definition]." [OBOL:automatic]
synonym: "foregut endoderm" EXACT [OBOL:automatic]
xref: EHDAA2:0004568
xref: EHDAA:524
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0005911 ! endo-epithelium
is_a: UBERON:0015833 ! foregut epithelium
intersection_of: UBERON:0000490 ! unilaminar epithelium
intersection_of: develops_from UBERON:0000925 ! endoderm
intersection_of: part_of UBERON:0001041 ! foregut
property_value: editor_note "TODO - check" xsd:string

[Term]
id: UBERON:0003259
name: endoderm of midgut
namespace: uberon
def: "An endoderm that is part of a midgut [Automatically generated definition]." [OBOL:automatic]
synonym: "midgut endoderm" EXACT [OBOL:automatic]
xref: EHDAA:987
xref: EMAPA:16257
xref: RETIRED_EHDAA2:0001194
xref: VHOG:0001080
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0003352 ! epithelium of midgut
is_a: UBERON:0005911 ! endo-epithelium
intersection_of: UBERON:0000490 ! unilaminar epithelium
intersection_of: develops_from UBERON:0000925 ! endoderm
intersection_of: part_of UBERON:0001045 ! midgut
property_value: editor_note "TODO - check" xsd:string

[Term]
id: UBERON:0003260
name: endoderm of hindgut
namespace: uberon
def: "An endoderm that is part of a hindgut [Automatically generated definition]." [OBOL:automatic]
synonym: "hindgut endoderm" EXACT [OBOL:automatic]
xref: EHDAA:979
xref: RETIRED_EHDAA2:0000781
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0003353 ! epithelium of hindgut
is_a: UBERON:0005911 ! endo-epithelium
intersection_of: UBERON:0000490 ! unilaminar epithelium
intersection_of: develops_from UBERON:0000925 ! endoderm
intersection_of: part_of UBERON:0001046 ! hindgut
property_value: editor_note "TODO - check" xsd:string

[Term]
id: UBERON:0003265
name: chorionic mesenchyme
namespace: uberon
alt_id: UBERON:0003423
def: "A mesenchyme that is part of a chorion." [OBOL:automatic]
synonym: "chorion mesenchyme" EXACT [OBOL:automatic]
synonym: "chorion mesoderm" EXACT [RETIRED_EHDAA2:0000247]
synonym: "chorionic mesenchyme" EXACT [EHDAA2:0003245]
synonym: "mesenchyme of chorion" EXACT []
synonym: "mesenchyme of chorion (vertebrates)" EXACT [OBOL:automatic]
xref: EHDAA2:0003245
xref: EHDAA:154
xref: EMAPA:16114
xref: EMAPA:16266
xref: RETIRED_EHDAA2:0000247
xref: VHOG:0000620
is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure
is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue
is_a: UBERON:0010333 ! extraembryonic membrane mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0003124 ! chorion membrane
relationship: develops_from UBERON:0004871 {source="ISBN:0073040584"} ! somatic layer of lateral plate mesoderm
relationship: part_of UBERON:0003124 ! chorion membrane
property_value: editor_note "TODO - check" xsd:string

[Term]
id: UBERON:0003269
name: skeletal muscle tissue of eye
namespace: uberon
def: "A portion of skeletal muscle tissue that is part of a eye [Automatically generated definition]." [OBOL:automatic]
synonym: "eye skeletal muscle" EXACT [OBOL:automatic]
synonym: "eye skeletal muscle group" RELATED [EHDAA2:0000486]
synonym: "eye skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of eye" EXACT [OBOL:automatic]
xref: EHDAA2:0000486
xref: EHDAA:2923
xref: EMAPA:17844
is_a: UBERON:0001134 ! skeletal muscle tissue
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0001134 ! skeletal muscle tissue
intersection_of: part_of UBERON:0000019 ! camera-type eye
relationship: part_of UBERON:0000019 ! camera-type eye

[Term]
id: UBERON:0003277
name: skeleton of upper jaw
namespace: uberon
def: "A subdivision of the skeleton that corresponds to the upper part of the mouth. The lower jaw skeleton includes the following elements, when present: upper jaw teeth, the maxilla and other lower jaw bones." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "upper jaw" BROAD [MA:0001908]
synonym: "upper jaw skeleton" EXACT []
xref: AAO:0000622
xref: EHDAA2:0002128
xref: EHDAA:8041
xref: EMAPA:17927
xref: FMA:54397
xref: MA:0001908
xref: VHOG:0000429
xref: XAO:0003087
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0010912 ! subdivision of skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: skeleton_of UBERON:0001709 ! upper jaw region
relationship: part_of UBERON:0001708 ! jaw skeleton
relationship: part_of UBERON:0001709 ! upper jaw region
relationship: skeleton_of UBERON:0001709 ! upper jaw region
property_value: UBPROP:0000003 "The jaw joint of all jawed vertebrates, except for mammals, involves the quadrate and articular bones, or the posterior ends of the palatoquadrate and mandibular cartilages; A correlate of the conversion of the articular and quadrate bones to the malleus and incus is that all adult mammals have a jaw joint that lies between the dentary of the lower jaw and the squamosal bone of the skull roof.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000429", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.241 and p.101", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "EMAPA/MA placement unclear. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/102" xsd:string {external_ontology="EMAPA"}

[Term]
id: UBERON:0003278
name: skeleton of lower jaw
namespace: uberon
def: "A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "lower jaw" BROAD [MA:0001906, ZFA:0001273]
synonym: "lower jaw skeleton" EXACT [AAO:0000274]
synonym: "mandible" BROAD [ZFA:0001273]
synonym: "mandibles" RELATED OMO:0003004 [TAO:0001273]
synonym: "mandibular series" RELATED [ZFA:0001273]
xref: AAO:0000274
xref: EHDAA2:0004606
xref: EHDAA:8005
xref: EMAPA:17906
xref: EMAPA:17910
xref: FMA:54398
xref: MA:0001906
xref: TAO:0001273
xref: VHOG:0000428
xref: XAO:0003084
xref: ZFA:0001273
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0010912 ! subdivision of skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: skeleton_of UBERON:0001710 ! lower jaw region
relationship: overlaps UBERON:0008895 {source="VHOG-modified"} ! splanchnocranium
relationship: part_of UBERON:0001708 ! jaw skeleton
relationship: part_of UBERON:0001710 {source="EHDAA2"} ! lower jaw region
relationship: skeleton_of UBERON:0001710 ! lower jaw region
property_value: UBPROP:0000001 "The ventral portion of the first pharyngeal arch, comprising the lower jaw.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001273", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "The jaw joint of all jawed vertebrates, except for mammals, involves the quadrate and articular bones, or the posterior ends of the palatoquadrate and mandibular cartilages; A correlate of the conversion of the articular and quadrate bones to the malleus and incus is that all adult mammals have a jaw joint that lies between the dentary of the lower jaw and the squamosal bone of the skull roof.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000428", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.241 and p.101", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "Inclusion of the FMA class 'lower jaw' is debatable - this mostly corresponds to the lower jaw skeleton (with 'maxillary part of mouth' corresponding to the upper jaw region); however, the FMA class also includes gingiva. See also: https://github.com/obophenotype/mouse-anatomy-ontology/issues/102" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0003281
name: mesentery of stomach
namespace: uberon
def: "The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum." [http://medical-dictionary.thefreedictionary.com/mesogastrium]
subset: pheno_slim
synonym: "mesentery of ventriculus" EXACT [OBOL:automatic]
synonym: "mesogaster" EXACT [http://medical-dictionary.thefreedictionary.com/mesogastrium]
synonym: "mesogastium" EXACT [MA:0001617]
synonym: "mesogastrium" EXACT [http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/peritoneum.html]
synonym: "stomach mesentery" EXACT [Obol:obol]
synonym: "ventriculus mesentery" EXACT [OBOL:automatic]
xref: EHDAA2:0001922
xref: EHDAA:2999
xref: EMAPA:17024
xref: MA:0001617
xref: SCTID:261623000
xref: VHOG:0000358
is_a: UBERON:0004854 {source="MA"} ! gastrointestinal system mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0000945 ! stomach
relationship: contributes_to_morphology_of UBERON:0000945 ! stomach
relationship: part_of UBERON:0000945 {source="MA"} ! stomach
property_value: editor_note "TODO - check primitive vs developed" xsd:string
property_value: UBPROP:0000001 "The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000358", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/mesogastrium"}

[Term]
id: UBERON:0003282
name: mesentery of heart
namespace: uberon
def: "A mesentery that surrounds the heart." [MA:th]
synonym: "cardiac mesentery" RELATED [EMAPA:16212]
synonym: "heart mesentery" EXACT [OBOL:automatic]
synonym: "mesocardium" RELATED [MA:0000098]
xref: EHDAA:432
xref: EMAPA:16212
xref: RETIRED_EHDAA2:0000739
xref: VHOG:0000353
is_a: UBERON:0002095 ! mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart

[Term]
id: UBERON:0003283
name: mesentery of oesophagus
namespace: uberon
def: "A mesentery that is part of a esophagus [Automatically generated definition]." [OBOL:automatic]
synonym: "esophagus mesentery" EXACT [MA:0001569]
synonym: "gullet mesentery" EXACT [OBOL:automatic]
synonym: "mesentery of esophagus" EXACT [OBOL:automatic]
synonym: "mesentery of gullet" EXACT [OBOL:automatic]
synonym: "meso-esophagus" EXACT []
synonym: "oesophagus mesentery" EXACT [VHOG:0000415]
xref: EHDAA2:0001288
xref: EHDAA:2943
xref: EMAPA:16836
xref: MA:0001569
xref: VHOG:0000415
is_a: UBERON:0001975 ! serosa of esophagus
is_a: UBERON:0002095 ! mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0001043 ! esophagus
property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000415", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003284
name: mesentery of midgut
namespace: uberon
def: "A mesentery that is part of a midgut [Automatically generated definition]." [OBOL:automatic]
synonym: "midgut mesentery" EXACT [OBOL:automatic]
xref: EHDAA2:0001202
xref: EHDAA:3031
xref: EMAPA:16721
xref: EMAPA:17039
xref: EMAPA:17197
xref: VHOG:0000413
is_a: UBERON:0002095 ! mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0001045 ! midgut
relationship: part_of UBERON:0001045 ! midgut
property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000413", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003294
name: gland of foregut
namespace: uberon
def: "A gland that is part of a foregut [Automatically generated definition]." [OBOL:automatic]
synonym: "foregut gland" EXACT [OBOL:automatic]
xref: EHDAA2:0000567
xref: EHDAA:950
xref: EMAPA:16557
xref: VHOG:0000650
is_a: UBERON:0003408 ! gland of digestive tract
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0001041 ! foregut
relationship: part_of UBERON:0001041 ! foregut

[Term]
id: UBERON:0003295
name: pharyngeal gland
namespace: uberon
def: "Racemose mucous glands beneath the mucous membrane of the pharynx." [http://www.biology-online.org/dictionary/]
subset: organ_slim
synonym: "glandulae pharyngeae" RELATED [BTO:0004849]
synonym: "pharynx gland" EXACT [EHDAA2:0001461]
xref: BTO:0004849
xref: EHDAA2:0001461
xref: EHDAA:2967
xref: FMA:55075
is_a: UBERON:0003408 ! gland of digestive tract
is_a: UBERON:0036225 ! respiratory system gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0001042 ! chordate pharynx
relationship: part_of UBERON:0001042 {source="BTO"} ! chordate pharynx

[Term]
id: UBERON:0003297
name: gland of integumental system
namespace: uberon
def: "A gland that is part of a integumental system [Automatically generated definition]." [OBOL:automatic]
synonym: "integumental gland" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "integumental system gland" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "integumentary gland" EXACT [http://orcid.org/0000-0002-6601-2165]
xref: EHDAA2:0000837
xref: EHDAA:6522
xref: EMAPA:17758
xref: MA:0000144
xref: VHOG:0000654
is_a: UBERON:0002530 ! gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0002416 ! integumental system
relationship: part_of UBERON:0002416 ! integumental system

[Term]
id: UBERON:0003304
name: mesoderm blood island
namespace: uberon
alt_id: UBERON:0003305
def: "A blood island that is part of a mesoderm." [OBOL:automatic]
synonym: "mesenchyme blood island" RELATED [OBOL:automatic]
synonym: "mesoderm blood islands" EXACT OMO:0003004 [EHDAA2:0003241]
xref: EHDAA2:0003241
xref: EHDAA:170
xref: EMAPA:16115
is_a: UBERON:0003061 ! blood island
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0003061 ! blood island
intersection_of: part_of UBERON:0000926 ! mesoderm
relationship: part_of UBERON:0000926 ! mesoderm
relationship: part_of UBERON:0007798 {source="EHDAA2"} ! vascular system
property_value: UBPROP:0000012 "in EHDAA2, gives rise to blood and dorsal aorta" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0003312
name: mesenchyme of testis
namespace: uberon
def: "Mesenchyme that is part of a developing testis [Automatically generated definition]." [OBOL:automatic]
synonym: "testis mesenchyme" EXACT [OBOL:automatic]
xref: EHDAA2:0002010
xref: EHDAA:8150
xref: EMAPA:35858
xref: VHOG:0001442
is_a: UBERON:0003855 ! gonad mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0000473 ! testis
relationship: part_of UBERON:0000473 ! testis

[Term]
id: UBERON:0003314
name: eye mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a developing camera-type eye." [OBOL:automatic]
synonym: "mesenchyme of eye" EXACT [OBOL:automatic]
xref: EHDAA2:0000485
xref: EHDAA:2910
xref: EMAPA:16673
xref: VHOG:0001084
is_a: UBERON:0007213 ! mesenchyme derived from head neural crest
is_a: UBERON:0009891 ! facial mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0000019 ! camera-type eye
relationship: develops_from UBERON:0009920 {source="EHDAA2"} ! optic neural crest
relationship: part_of UBERON:0000019 ! camera-type eye
property_value: editor_note "TODO - change mesenchyme relationships to precursor_of" xsd:string

[Term]
id: UBERON:0003315
name: mesenchyme of ovary
namespace: uberon
def: "Mesenchyme that is part of a developing ovary [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "female reproductive system gonad mesenchyme" EXACT [OBOL:automatic]
synonym: "female reproductive system gonada mesenchyme" EXACT [OBOL:automatic]
synonym: "gonad of female reproductive system mesenchyme" EXACT [OBOL:automatic]
synonym: "gonada of female reproductive system mesenchyme" EXACT [OBOL:automatic]
synonym: "mesenchyme of female reproductive system gonad" EXACT [OBOL:automatic]
synonym: "mesenchyme of female reproductive system gonada" EXACT [OBOL:automatic]
synonym: "mesenchyme of gonad of female reproductive system" EXACT [OBOL:automatic]
synonym: "mesenchyme of gonada of female reproductive system" EXACT [OBOL:automatic]
synonym: "ovary mesenchyme" EXACT [OBOL:automatic]
xref: EHDAA2:0001362
xref: EHDAA:8128
xref: VHOG:0001441
is_a: UBERON:0003855 ! gonad mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0000992 ! ovary
relationship: part_of UBERON:0000992 ! ovary
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003316
name: mesenchyme of yolk sac
namespace: uberon
alt_id: UBERON:0003264
def: "The portion of the yolk sac that is derived from mesoderm and consists of mesenchyme." [UBERON:cjm]
synonym: "yolk sac mesenchyme" EXACT [OBOL:automatic]
xref: EHDAA2:0002216
xref: EHDAA:168
xref: EHDAA:205
xref: EMAPA:16087
xref: EMAPA:16267
xref: VHOG:0000503
xref: VHOG:0000617
is_a: UBERON:0010333 ! extraembryonic membrane mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0001040 ! yolk sac
relationship: part_of UBERON:0001040 ! yolk sac

[Term]
id: UBERON:0003323
name: mesenchyme of upper jaw
namespace: uberon
def: "Mesenchyme that is part of a developing upper jaw [Automatically generated definition]." [OBOL:automatic]
synonym: "mesenchyme of palatoquadrate arch" EXACT [OBOL:automatic]
synonym: "palatoquadrate arch mesenchyme" EXACT [OBOL:automatic]
synonym: "upper jaw mesenchyme" EXACT [OBOL:automatic]
xref: EHDAA2:0002124
xref: EHDAA:8031
xref: EMAPA:17929
xref: VHOG:0001099
is_a: UBERON:0009891 ! facial mesenchyme
is_a: UBERON:0034995 ! jaw mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0001709 ! upper jaw region
relationship: develops_from UBERON:0009526 {source="EHDAA2"} ! maxillary process mesenchyme
relationship: part_of UBERON:0001709 ! upper jaw region

[Term]
id: UBERON:0003324
name: mesenchyme of lower jaw
namespace: uberon
def: "Mesenchyme that is part of a developing lower jaw [Automatically generated definition]." [OBOL:automatic]
synonym: "lower jaw mesenchyme" EXACT [OBOL:automatic]
synonym: "mesenchyme of ventral mandibular arch" EXACT [OBOL:automatic]
synonym: "ventral mandibular arch mesenchyme" EXACT [OBOL:automatic]
xref: EHDAA2:0001024
xref: EHDAA:8003
xref: EMAPA:17916
xref: VHOG:0001069
is_a: UBERON:0034995 ! jaw mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0001710 ! lower jaw region
relationship: develops_from UBERON:0006905 {source="EHDAA2"} ! mandibular process mesenchyme
relationship: part_of UBERON:0001710 ! lower jaw region

[Term]
id: UBERON:0003329
name: submucosa of anal canal
namespace: uberon
def: "A submucosa that is part of an anal canal [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "anal canal submucosa" EXACT [OBOL:automatic]
synonym: "anal canal viewed anatomically submucosa" EXACT [OBOL:automatic]
synonym: "anal region submucosa" EXACT [OBOL:automatic]
synonym: "anatomical anal canal submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of anal canal viewed anatomically" EXACT [OBOL:automatic]
synonym: "submucosa of anal region" EXACT [OBOL:automatic]
synonym: "submucosa of anatomical anal canal" EXACT [OBOL:automatic]
xref: EMAPA:27217
xref: EMAPA:27227
xref: EMAPA:27535
xref: FMA:85399
xref: SCTID:7892006
is_a: UBERON:0001208 ! submucosa of large intestine
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0000159 ! anal canal
relationship: part_of UBERON:0000159 ! anal canal
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003330
name: submucosa of rectum
namespace: uberon
def: "The submucous layer of the wall of the rectum." [BTO:0002114]
synonym: "rectal submucosa" EXACT [FMA:15034]
synonym: "rectum submucosa" EXACT [OBOL:automatic]
synonym: "tela submucosa recti" EXACT OMO:0003011 [BTO:0002114]
xref: BTO:0002114
xref: EMAPA:27083
xref: FMA:15034
xref: SCTID:71683001
is_a: UBERON:0001208 ! submucosa of large intestine
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001052 ! rectum
relationship: part_of UBERON:0001052 ! rectum

[Term]
id: UBERON:0003331
name: submucosa of colon
namespace: uberon
def: "A submucosa that is part of a colon [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "colon submucosa" EXACT [OBOL:automatic]
synonym: "colonic submucosa" EXACT [FMA:14985]
synonym: "large bowel submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of large bowel" EXACT [OBOL:automatic]
xref: EMAPA:27379
xref: FMA:14985
xref: MA:0003200
xref: SCTID:61647009
is_a: UBERON:0001208 ! submucosa of large intestine
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003332
name: submucosa of duodenum
namespace: uberon
def: "A submucosa that is part of a duodenum [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "doudenal submucosa" EXACT [FMA:14943]
synonym: "duodenal submucosa" EXACT [FMA:14943]
synonym: "duodenum submucosa" EXACT [OBOL:automatic]
xref: EMAPA:27027
xref: EMAPA:27097
xref: EMAPA:27239
xref: FMA:14943
xref: MA:0003213
xref: SCTID:76519004
is_a: UBERON:0001205 ! submucosa of small intestine
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: part_of UBERON:0002114 ! duodenum
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003334
name: serosa of rectum
namespace: uberon
def: "A serous membrane that is part of a rectum [Automatically generated definition]." [OBOL:automatic]
synonym: "rectal serosa" EXACT [FMA:15039]
synonym: "rectum serosa" EXACT [OBOL:automatic]
synonym: "rectum serous membrane" EXACT [OBOL:automatic]
synonym: "serous membrane of rectum" EXACT [OBOL:automatic]
synonym: "visceral peritoneum of rectum" EXACT [FMA:15039]
xref: EMAPA:27087
xref: FMA:15039
is_a: UBERON:0001209 ! serosa of large intestine
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0001052 ! rectum
relationship: part_of UBERON:0001052 ! rectum

[Term]
id: UBERON:0003335
name: serosa of colon
namespace: uberon
def: "A serous membrane that is part of a colon [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "colon serosa" EXACT [OBOL:automatic]
synonym: "colon serous membrane" EXACT [OBOL:automatic]
synonym: "colonic serosa" EXACT [FMA:14990]
synonym: "large bowel serosa" EXACT [OBOL:automatic]
synonym: "large bowel serous membrane" EXACT [OBOL:automatic]
synonym: "serosa of large bowel" EXACT [OBOL:automatic]
synonym: "serous membrane of colon" EXACT [OBOL:automatic]
synonym: "serous membrane of large bowel" EXACT [OBOL:automatic]
synonym: "visceral peritoneum of colon" EXACT [FMA:14990]
xref: EMAPA:27387
xref: FMA:14990
xref: MA:0003199
xref: SCTID:90132000
is_a: UBERON:0001209 ! serosa of large intestine
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003336
name: serosa of duodenum
namespace: uberon
def: "A serous membrane that is part of a duodenum [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "doudenal serosa" EXACT [FMA:14948]
synonym: "duodenal serosa" EXACT [FMA:14948]
synonym: "duodenum serosa" EXACT [OBOL:automatic]
synonym: "duodenum serous membrane" EXACT [OBOL:automatic]
synonym: "serous membrane of duodenum" EXACT [OBOL:automatic]
synonym: "visceral peritoneum of duodenum" EXACT [FMA:14948]
xref: EMAPA:27247
xref: FMA:14948
xref: MA:0003212
xref: SCTID:1236009
is_a: UBERON:0001206 ! serosa of small intestine
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: part_of UBERON:0002114 ! duodenum
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000010 "1st part serosa, 2nd - 4th adventitia" xsd:string

[Term]
id: UBERON:0003338
name: ganglion of peripheral nervous system
namespace: uberon
def: "A spatially aggregated collection of nerve cell bodies in the PNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections. (CUMBO)." [BIRNLEX:2548]
subset: cumbo
synonym: "peripheral nervous system ganglion" EXACT [OBOL:automatic]
xref: BIRNLEX:2548
xref: BTO:0001123
xref: EMAPA:32814
xref: MA:0001161
is_a: UBERON:0000045 ! ganglion
intersection_of: UBERON:0000045 ! ganglion
intersection_of: part_of UBERON:0000010 ! peripheral nervous system
relationship: part_of UBERON:0000010 ! peripheral nervous system
property_value: UBPROP:0000012 "we follow MA in including separate classes for ganglion and peripheral nervous system, even though for vertebrates gangia are always in the PNS" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0003339
name: ganglion of central nervous system
namespace: uberon
def: "A ganglion that is part of a central nervous system [Automatically generated definition]." [OBOL:automatic]
synonym: "central nervous system ganglion" EXACT [OBOL:automatic]
synonym: "ganglion of neuraxis" EXACT [OBOL:automatic]
synonym: "neuraxis ganglion" EXACT [OBOL:automatic]
xref: EHDAA2:0000227
xref: EMAPA:16658
xref: FMA:83843
is_a: UBERON:0000045 ! ganglion
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000045 ! ganglion
intersection_of: part_of UBERON:0001017 ! central nervous system
relationship: part_of UBERON:0001017 ! central nervous system
property_value: UBPROP:0000012 "this has no subclasses in FMA. In EHDAA2 and EMAPA it has only the cranial ganglia" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0003342
name: mucosa of anal canal
namespace: uberon
def: "A mucosa that is part of an anal canal [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "anal canal mucosa" EXACT [OBOL:automatic]
synonym: "anal canal mucosa of organ" EXACT [OBOL:automatic]
synonym: "anal canal mucous membrane" EXACT [OBOL:automatic]
synonym: "anal canal organ mucosa" EXACT [OBOL:automatic]
synonym: "anal canal viewed anatomically mucosa" EXACT [OBOL:automatic]
synonym: "anal canal viewed anatomically mucosa of organ" EXACT [OBOL:automatic]
synonym: "anal canal viewed anatomically mucous membrane" EXACT [OBOL:automatic]
synonym: "anal canal viewed anatomically organ mucosa" EXACT [OBOL:automatic]
synonym: "anal mucosa" EXACT [FMA:74654]
synonym: "anal mucous membrane" EXACT [FMA:74654]
synonym: "anal region mucosa" EXACT [OBOL:automatic]
synonym: "anal region mucosa of organ" EXACT [OBOL:automatic]
synonym: "anal region mucous membrane" EXACT [OBOL:automatic]
synonym: "anal region organ mucosa" EXACT [OBOL:automatic]
synonym: "anatomical anal canal mucosa" EXACT [OBOL:automatic]
synonym: "anatomical anal canal mucosa of organ" EXACT [OBOL:automatic]
synonym: "anatomical anal canal mucous membrane" EXACT [OBOL:automatic]
synonym: "anatomical anal canal organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of anal canal viewed anatomically" EXACT [OBOL:automatic]
synonym: "mucosa of anal region" EXACT [OBOL:automatic]
synonym: "mucosa of anatomical anal canal" EXACT [OBOL:automatic]
synonym: "mucosa of organ of anal canal" EXACT [OBOL:automatic]
synonym: "mucosa of organ of anal canal viewed anatomically" EXACT [OBOL:automatic]
synonym: "mucosa of organ of anal region" EXACT [OBOL:automatic]
synonym: "mucosa of organ of anatomical anal canal" EXACT [OBOL:automatic]
synonym: "mucous membrane of anal canal" EXACT [OBOL:automatic]
synonym: "mucous membrane of anal canal viewed anatomically" EXACT [OBOL:automatic]
synonym: "mucous membrane of anal region" EXACT [OBOL:automatic]
synonym: "mucous membrane of anatomical anal canal" EXACT [OBOL:automatic]
synonym: "organ mucosa of anal canal" EXACT [OBOL:automatic]
synonym: "organ mucosa of anal canal viewed anatomically" EXACT [OBOL:automatic]
synonym: "organ mucosa of anal region" EXACT [OBOL:automatic]
synonym: "organ mucosa of anatomical anal canal" EXACT [OBOL:automatic]
xref: EMAPA:27531
xref: FMA:74654
xref: NCIT:C60784
xref: SCTID:362170004
xref: UMLS:C0227414 {source="ncithesaurus:Anal_Mucosa"}
is_a: UBERON:0001207 ! mucosa of large intestine
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000159 ! anal canal
relationship: part_of UBERON:0000159 ! anal canal
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003343
name: mucosa of oral region
namespace: uberon
def: "A mucosa that is part of a oral opening [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of oral opening" EXACT [OBOL:automatic]
synonym: "mucosa of oral part of face" EXACT [OBOL:automatic]
synonym: "mucosa of organ of oral opening" EXACT [OBOL:automatic]
synonym: "mucosa of organ of oral part of face" EXACT [OBOL:automatic]
synonym: "mucosa of organ of oral region" EXACT [OBOL:automatic]
synonym: "mucosa of organ of subdivision of mouth" EXACT [OBOL:automatic]
synonym: "mucosa of subdivision of mouth" EXACT [OBOL:automatic]
synonym: "mucous membrane of oral opening" EXACT [OBOL:automatic]
synonym: "mucous membrane of oral part of face" EXACT [OBOL:automatic]
synonym: "mucous membrane of oral region" EXACT [OBOL:automatic]
synonym: "mucous membrane of subdivision of mouth" EXACT [OBOL:automatic]
synonym: "oral opening mucosa" EXACT [OBOL:automatic]
synonym: "oral opening mucosa of organ" EXACT [OBOL:automatic]
synonym: "oral opening mucous membrane" EXACT [OBOL:automatic]
synonym: "oral opening organ mucosa" EXACT [OBOL:automatic]
synonym: "oral part of face mucosa" EXACT [OBOL:automatic]
synonym: "oral part of face mucosa of organ" EXACT [OBOL:automatic]
synonym: "oral part of face mucous membrane" EXACT [OBOL:automatic]
synonym: "oral part of face organ mucosa" EXACT [OBOL:automatic]
synonym: "oral region mucosa" EXACT [OBOL:automatic]
synonym: "oral region mucosa of organ" EXACT [OBOL:automatic]
synonym: "oral region mucous membrane" EXACT [OBOL:automatic]
synonym: "oral region organ mucosa" EXACT [OBOL:automatic]
synonym: "organ mucosa of oral opening" EXACT [OBOL:automatic]
synonym: "organ mucosa of oral part of face" EXACT [OBOL:automatic]
synonym: "organ mucosa of oral region" EXACT [OBOL:automatic]
synonym: "organ mucosa of subdivision of mouth" EXACT [OBOL:automatic]
synonym: "subdivision of mouth mucosa" EXACT [OBOL:automatic]
synonym: "subdivision of mouth mucosa of organ" EXACT [OBOL:automatic]
synonym: "subdivision of mouth mucous membrane" EXACT [OBOL:automatic]
synonym: "subdivision of mouth organ mucosa" EXACT [OBOL:automatic]
xref: EMAPA:26937
xref: SCTID:362083000
is_a: UBERON:0003729 ! mouth mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000166 ! oral opening
relationship: part_of UBERON:0000166 ! oral opening

[Term]
id: UBERON:0003346
name: mucosa of rectum
namespace: uberon
def: "A mucosa that is part of a rectum [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of organ of rectum" EXACT [OBOL:automatic]
synonym: "mucous membrane of rectum" EXACT [OBOL:automatic]
synonym: "organ mucosa of rectum" EXACT [OBOL:automatic]
synonym: "rectal mucosa" EXACT [FMA:15033]
synonym: "rectal mucous membrane" EXACT [FMA:15033]
synonym: "rectum mucosa" EXACT [OBOL:automatic]
synonym: "rectum mucosa of organ" EXACT [OBOL:automatic]
synonym: "rectum mucous membrane" EXACT [OBOL:automatic]
synonym: "rectum organ mucosa" EXACT [OBOL:automatic]
xref: CALOHA:TS-2107
xref: EMAPA:27081
xref: FMA:15033
xref: MA:0003218
xref: SCTID:362167003
is_a: UBERON:0001207 ! mucosa of large intestine
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001052 ! rectum
relationship: part_of UBERON:0001052 ! rectum

[Term]
id: UBERON:0003350
name: epithelium of mucosa
namespace: uberon
def: "A layer of epithelial cells on the surface of the mucosa." [BTO:0003752]
comment: lies on top of lamina propria
synonym: "lamina epithelialis mucosa" RELATED [BTO:0003752]
synonym: "lamina epithelialis mucosae" RELATED [BTO:0003752]
xref: BTO:0003752
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000344 ! mucosa
relationship: part_of UBERON:0000344 ! mucosa

[Term]
id: UBERON:0003351
name: pharyngeal epithelium
namespace: uberon
def: "An epithelium that is part of a pharynx [Automatically generated definition]." [OBOL:automatic]
subset: vertebrate_core
synonym: "epithelial tissue of pharynx" EXACT [OBOL:automatic]
synonym: "epithelium of pharynx" EXACT [OBOL:automatic]
synonym: "pharynx epithelial tissue" EXACT [OBOL:automatic]
synonym: "pharynx epithelium" EXACT [OBOL:automatic]
xref: BSA:0000112
xref: BTO:0005240
xref: EMAPA:16708
xref: MA:0002725
xref: RETIRED_EHDAA2:0001460
xref: TAO:0001174
xref: XAO:0003202
xref: ZFA:0001174
is_a: UBERON:0000490 {gci_relation="part_of", gci_filler="NCBITaxon:7955", source="ZFA"} ! unilaminar epithelium
is_a: UBERON:0003929 ! digestive tract epithelium
is_a: UBERON:0004807 ! respiratory system epithelium
is_a: UBERON:0005911 ! endo-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001042 ! chordate pharynx
relationship: develops_from UBERON:0007690 {source="ZFA"} ! early pharyngeal endoderm
relationship: part_of UBERON:0001042 {source="ZFA"} ! chordate pharynx
property_value: UBPROP:0000001 "Epithelium lining the pharynx consisting largely of simple columnar epithelium with a short segment (1mm) of stratified squamous epithelium on the ventral side. Chen et al, 2007.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001174", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0003352
name: epithelium of midgut
namespace: uberon
def: "An epithelium that is part of a midgut." [OBOL:automatic]
synonym: "epithelial tissue of midgut" EXACT [OBOL:automatic]
synonym: "midgut epithelial tissue" EXACT [OBOL:automatic]
synonym: "midgut epithelium" EXACT [BTO:0005053, OBOL:automatic]
xref: BTO:0005053
xref: EHDAA2:0001195
xref: EMAPA:16569
xref: MA:0003205
is_a: UBERON:0003929 ! digestive tract epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001045 ! midgut
relationship: part_of UBERON:0001045 {source="BTO"} ! midgut

[Term]
id: UBERON:0003353
name: epithelium of hindgut
namespace: uberon
def: "An epithelium that is part of a hindgut [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of hindgut" EXACT [OBOL:automatic]
synonym: "hindgut epithelial tissue" EXACT [OBOL:automatic]
synonym: "hindgut epithelium" EXACT [OBOL:automatic]
xref: EHDAA2:0000782
xref: EMAPA:16717
xref: MA:0003206
is_a: UBERON:0003929 ! digestive tract epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001046 ! hindgut
relationship: part_of UBERON:0001046 ! hindgut

[Term]
id: UBERON:0003354
name: epithelium of rectum
namespace: uberon
def: "An epithelium that is part of a rectum [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of rectum" EXACT [OBOL:automatic]
synonym: "rectal epithelium" EXACT [FMA:17510]
synonym: "rectum epithelial tissue" EXACT [OBOL:automatic]
synonym: "rectum epithelium" EXACT [OBOL:automatic]
xref: CALOHA:TS-2066
xref: EHDAA2:0001594
xref: EMAPA:17898
xref: FMA:17510
xref: MA:0003219
xref: VHOG:0001037
is_a: UBERON:0001278 ! epithelium of large intestine
is_a: UBERON:0016885 ! epithelium of terminal part of digestive tract
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001052 ! rectum
relationship: part_of UBERON:0001052 ! rectum

[Term]
id: UBERON:0003364
name: epithelium of right lung
namespace: uberon
def: "An epithelium that is part of a right lung [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of right lung" EXACT [OBOL:automatic]
synonym: "right lung epithelial tissue" EXACT [OBOL:automatic]
synonym: "right lung epithelium" EXACT [OBOL:automatic]
xref: EMAPA:17663
xref: MA:0003132
is_a: UBERON:0000115 ! lung epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0002167 ! right lung
relationship: part_of UBERON:0002167 ! right lung

[Term]
id: UBERON:0003365
name: epithelium of left lung
namespace: uberon
def: "An epithelium that is part of a left lung [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of left lung" EXACT [OBOL:automatic]
synonym: "left lung epithelial tissue" EXACT [OBOL:automatic]
synonym: "left lung epithelium" EXACT [OBOL:automatic]
xref: EMAPA:17655
xref: MA:0003131
is_a: UBERON:0000115 ! lung epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0002168 ! left lung
relationship: part_of UBERON:0002168 ! left lung

[Term]
id: UBERON:0003371
name: pelvic appendage bud ectoderm
namespace: uberon
alt_id: UBERON:0005232
def: "An unilaminar epithelium that surrounds a pelvic appendage bud." [OBOL:automatic]
synonym: "hindlimb bud ectoderm" NARROW SENSU [EMAPA:16780]
synonym: "hindlimb ectoderm" EXACT [VHOG:0001048]
synonym: "hindlimb ectoderm" NARROW SENSU [VHOG:0001048]
synonym: "leg ectoderm" RELATED [OBOL:automatic]
synonym: "lower limb bud ectoderm" NARROW SENSU [EHDAA2:0001034]
synonym: "pelvic fin bud ectoderm" NARROW SENSU []
xref: EHDAA2:0001034
xref: EMAPA:16780
xref: VHOG:0001048
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0000490 ! unilaminar epithelium
intersection_of: bounding_layer_of UBERON:0005420 ! pelvic appendage bud
relationship: bounding_layer_of UBERON:0005420 ! pelvic appendage bud
relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm
relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm
relationship: part_of UBERON:0005420 ! pelvic appendage bud

[Term]
id: UBERON:0003372
name: pectoral appendage bud ectoderm
namespace: uberon
alt_id: UBERON:0005231
alt_id: UBERON:0005663
def: "An unilaminar epithelium that surrounds a pectoral appendage bud." [OBOL:automatic]
synonym: "arm ectoderm" RELATED [OBOL:automatic]
synonym: "forelimb bud ectoderm" NARROW SENSU [EMAPA:16407]
synonym: "forelimb ectoderm" NARROW SENSU [VHOG:0001047]
synonym: "pectoral fin bud ectoderm" NARROW SENSU []
synonym: "upper limb bud ectoderm" NARROW SENSU [EHDAA2:0002134]
synonym: "wing ectoderm" NARROW SENSU [Geisha:syn, NCBITaxon:8782]
xref: EHDAA2:0002134
xref: EMAPA:16407
xref: VHOG:0001047
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0000490 ! unilaminar epithelium
intersection_of: bounding_layer_of UBERON:0005419 ! pectoral appendage bud
relationship: bounding_layer_of UBERON:0005419 ! pectoral appendage bud
relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm
relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm
relationship: part_of UBERON:0005419 ! pectoral appendage bud

[Term]
id: UBERON:0003374
name: chorionic ectoderm
namespace: uberon
def: "An extraembryonic structure that develops_from a ectoderm and is part of a chorion." [OBOL:automatic]
synonym: "chorion ectoderm" EXACT [OBOL:automatic]
synonym: "chorion epithelium" RELATED []
synonym: "chorionic epithelium" RELATED [BTO:0005145]
xref: BTO:0005145
xref: EMAPA:16113
is_a: UBERON:0000478 ! extraembryonic structure
intersection_of: UBERON:0000478 ! extraembryonic structure
intersection_of: develops_from UBERON:0000924 ! ectoderm
intersection_of: part_of UBERON:0003124 ! chorion membrane
relationship: develops_from UBERON:0000924 {source="ISBN:0073040584"} ! ectoderm
relationship: part_of UBERON:0003124 ! chorion membrane

[Term]
id: UBERON:0003379
name: cardiac muscle of right atrium
namespace: uberon
def: "A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "cardiac muscle of cardiac right atrium" EXACT [OBOL:automatic]
synonym: "cardiac muscle of heart right atrium" EXACT [OBOL:automatic]
synonym: "cardiac muscle tissue of heart right atrium" EXACT [OBOL:automatic]
synonym: "cardiac muscle tissue of right atrium" EXACT [OBOL:automatic]
synonym: "cardiac muscle tissue of right atrium of heart" EXACT [OBOL:automatic]
synonym: "myocardium of right atrium" EXACT []
synonym: "right atrium heart muscle" EXACT [EHDAA2:0004155]
synonym: "right atrium myocardium" EXACT [VHOG:0001227]
synonym: "textus muscularis of myocardium of right atrium" EXACT [OBOL:automatic]
synonym: "textus muscularis of myocardium of right atrium of heart" EXACT [OBOL:automatic]
synonym: "textus muscularis of myocardium of right cardiac atrium" EXACT [OBOL:automatic]
xref: EHDAA2:0004155
xref: EMAPA:17326
xref: FMA:7282
xref: SCTID:362018002
xref: VHOG:0001227
is_a: UBERON:0004490 ! cardiac muscle tissue of atrium
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002078 ! right cardiac atrium
relationship: part_of UBERON:0002078 ! right cardiac atrium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003380
name: cardiac muscle of left atrium
namespace: uberon
def: "A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]." [OBOL:automatic]
synonym: "cardiac left atrium cardiac muscle" EXACT [OBOL:automatic]
synonym: "cardiac left atrium cardiac muscle tissue" EXACT [OBOL:automatic]
synonym: "cardiac muscle of cardiac left atrium" EXACT [OBOL:automatic]
synonym: "cardiac muscle of heart left atrium" EXACT [OBOL:automatic]
synonym: "cardiac muscle of left atrium of heart" EXACT [OBOL:automatic]
synonym: "left atrium heart muscle" EXACT [EHDAA2:0004154]
synonym: "left atrium myocardium" EXACT [VHOG:0001225]
synonym: "myocardium of left atrium" EXACT []
synonym: "textus muscularis of myocardium of cardiac left atrium" EXACT [OBOL:automatic]
synonym: "textus muscularis of myocardium of heart left atrium" EXACT [OBOL:automatic]
synonym: "textus muscularis of myocardium of left atrium" EXACT [OBOL:automatic]
synonym: "textus muscularis of myocardium of left atrium of heart" EXACT [OBOL:automatic]
synonym: "textus muscularis of myocardium of left cardiac atrium" EXACT [OBOL:automatic]
xref: EHDAA2:0004154
xref: EMAPA:17320
xref: FMA:7285
xref: SCTID:189936008
xref: VHOG:0001225
is_a: UBERON:0004490 ! cardiac muscle tissue of atrium
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002079 ! left cardiac atrium
relationship: part_of UBERON:0002079 ! left cardiac atrium

[Term]
id: UBERON:0003381
name: cardiac muscle of right ventricle
namespace: uberon
def: "A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]." [OBOL:automatic]
synonym: "cardiac muscle tissue of right ventricle" EXACT [FMA:83452]
synonym: "right ventricle cardiac muscle" RELATED [VHOG:0001236]
synonym: "right ventricular cardiac muscle tissue" EXACT [GO:0003221]
xref: EMAPA:17342
xref: FMA:83452
xref: VHOG:0001236
is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002080 ! heart right ventricle
relationship: part_of UBERON:0002080 ! heart right ventricle

[Term]
id: UBERON:0003382
name: cardiac muscle of left ventricle
namespace: uberon
def: "A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]." [OBOL:automatic]
synonym: "cardiac muscle tissue of left ventricle" EXACT [FMA:83453]
synonym: "left ventricle cardiac muscle" RELATED [VHOG:0001234]
synonym: "left ventricular cardiac muscle tissue" EXACT [GO:0003220]
xref: EMAPA:17339
xref: FMA:83453
xref: VHOG:0001234
is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002084 ! heart left ventricle
relationship: part_of UBERON:0002084 ! heart left ventricle

[Term]
id: UBERON:0003383
name: cardiac muscle tissue of interventricular septum
namespace: uberon
def: "A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "cardiac muscle of interventricular septum" EXACT []
synonym: "cardiac muscle tissue of interventricular septum" EXACT [FMA:84084]
synonym: "interventricular septum cardiac muscle" EXACT [VHOG:0000999]
synonym: "interventricular septum heart muscle" EXACT [EHDAA2:0004158]
synonym: "interventricular septum muscle" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "interventricular septum myocardium" EXACT [VHOG:0000999]
xref: EHDAA2:0004158
xref: EMAPA:17335
xref: FMA:84084
xref: VHOG:0000999
is_a: UBERON:0004492 ! cardiac muscle tissue of cardiac septum
is_a: UBERON:0004667 ! interventricular septum muscular part
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002094 ! interventricular septum
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003384
name: skeletal muscle tissue of pharynx
namespace: uberon
def: "A portion of skeletal muscle tissue that is part of a pharynx [Automatically generated definition]." [OBOL:automatic]
synonym: "pharynx skeletal muscle" EXACT [OBOL:automatic]
synonym: "pharynx skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of pharynx" EXACT [OBOL:automatic]
xref: EMAPA:18963
is_a: UBERON:0004830 ! respiratory system skeletal muscle
intersection_of: UBERON:0001134 ! skeletal muscle tissue
intersection_of: part_of UBERON:0001042 ! chordate pharynx
relationship: part_of UBERON:0001042 ! chordate pharynx

[Term]
id: UBERON:0003386
name: smooth muscle of eye
namespace: uberon
def: "Any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi." [MGI:cwg, MP:0005247]
subset: pheno_slim
synonym: "ocular smooth muscle" EXACT [MA:0001268]
xref: EMAPA:18807
xref: MA:0001268
is_a: UBERON:0001135 ! smooth muscle tissue
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0000019 ! camera-type eye
relationship: contributes_to_morphology_of UBERON:0001015 ! musculature
relationship: part_of UBERON:0000019 ! camera-type eye
property_value: editor_note "Not clear if we need this and intra-ocular muscle. See issue #331. MA includes ciliary and iris smooth muscle" xsd:string

[Term]
id: UBERON:0003388
name: mesothelium of pericardial cavity
namespace: uberon
def: "A mesothelium that is part of a pericardium [Automatically generated definition]." [OBOL:automatic]
synonym: "cavity of pericardial sac meso-epithelium" EXACT [OBOL:automatic]
synonym: "cavity of pericardial sac mesothelium" EXACT [OBOL:automatic]
synonym: "meso-epithelium of cavity of pericardial sac" EXACT [OBOL:automatic]
synonym: "meso-epithelium of pericardial cavity" EXACT [OBOL:automatic]
synonym: "mesothelium of cavity of pericardial sac" EXACT [OBOL:automatic]
synonym: "pericardial cavity meso-epithelium" EXACT [OBOL:automatic]
synonym: "pericardial cavity mesothelium" EXACT [OBOL:automatic]
xref: RETIRED_EHDAA2:0001436
is_a: UBERON:0001136 ! mesothelium
intersection_of: UBERON:0001136 ! mesothelium
intersection_of: part_of UBERON:0002407 ! pericardium
relationship: part_of UBERON:0002407 ! pericardium

[Term]
id: UBERON:0003389
name: mesothelium of diaphragm
namespace: uberon
def: "A mesothelium that is part of a diaphragm [Automatically generated definition]." [OBOL:automatic]
synonym: "diaphragm meso-epithelium" EXACT [OBOL:automatic]
synonym: "diaphragm mesothelium" EXACT [OBOL:automatic]
synonym: "meso-epithelium of diaphragm" EXACT [OBOL:automatic]
synonym: "meso-epithelium of thoracic diaphragm" EXACT [OBOL:automatic]
synonym: "mesothelium of thoracic diaphragm" EXACT [OBOL:automatic]
synonym: "thoracic diaphragm meso-epithelium" EXACT [OBOL:automatic]
synonym: "thoracic diaphragm mesothelium" EXACT [OBOL:automatic]
xref: EMAPA:18429
is_a: UBERON:0001136 ! mesothelium
is_a: UBERON:0004807 ! respiratory system epithelium
intersection_of: UBERON:0001136 ! mesothelium
intersection_of: part_of UBERON:0001103 ! diaphragm
relationship: part_of UBERON:0001103 ! diaphragm

[Term]
id: UBERON:0003390
name: mesothelium of pleural cavity
namespace: uberon
def: "A mesothelium that is part of a pleural cavity [Automatically generated definition]." [OBOL:automatic]
synonym: "meso-epithelium of pleural cavity" EXACT [OBOL:automatic]
synonym: "mesothelium of pleura" EXACT [FMA:18148]
synonym: "pleura" RELATED [EMAPA:16775]
synonym: "pleural cavity meso-epithelium" EXACT [OBOL:automatic]
synonym: "pleural cavity mesothelium" EXACT [OBOL:automatic]
synonym: "pleural mesothelium" EXACT [EMAPA:16775]
xref: BTO:0003155
xref: EHDAA2:0001476
xref: EMAPA:16775
xref: FMA:18148
is_a: UBERON:0001136 ! mesothelium
intersection_of: UBERON:0001136 ! mesothelium
intersection_of: located_in UBERON:0002402 ! pleural cavity
relationship: located_in UBERON:0002402 ! pleural cavity

[Term]
id: UBERON:0003393
name: mesentery of urinary system
namespace: uberon
def: "A mesentery that is part of a urinary system [Automatically generated definition]." [OBOL:automatic]
synonym: "excretory system mesentery" EXACT [OBOL:automatic]
synonym: "mesentery of excretory system" EXACT [OBOL:automatic]
synonym: "mesentery of renal system" EXACT [OBOL:automatic]
synonym: "mesentery of systema urinaria" EXACT [OBOL:automatic]
synonym: "renal system mesentery" EXACT [OBOL:automatic]
synonym: "systema urinaria mesentery" EXACT [OBOL:automatic]
synonym: "urinary system mesentery" EXACT [OBOL:automatic]
xref: EMAPA:17367
xref: MA:0003233
is_a: UBERON:0002095 ! mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0001008 ! renal system
relationship: part_of UBERON:0001008 ! renal system

[Term]
id: UBERON:0003394
name: mesentery of hindgut
namespace: uberon
def: "A mesentery that is part of a hindgut [Automatically generated definition]." [OBOL:automatic]
synonym: "hindgut mesentery" EXACT [OBOL:automatic]
xref: EMAPA:16718
is_a: UBERON:0002095 ! mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0001046 ! hindgut
relationship: part_of UBERON:0001046 ! hindgut

[Term]
id: UBERON:0003395
name: mesentery of rectum
namespace: uberon
def: "A mesentery that is part of a rectum [Automatically generated definition]." [OBOL:automatic]
synonym: "rectum mesentery" EXACT [OBOL:automatic]
xref: EMAPA:18664
is_a: UBERON:0003334 ! serosa of rectum
is_a: UBERON:0004854 ! gastrointestinal system mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0001052 ! rectum

[Term]
id: UBERON:0003396
name: mesentery of colon
namespace: uberon
def: "A mesentery that is part of a colon [Automatically generated definition]." [OBOL:automatic]
synonym: "colon mesentery" EXACT [OBOL:automatic]
synonym: "large bowel mesentery" EXACT [OBOL:automatic]
synonym: "large intestinal mesentery" EXACT [FMA:14645]
synonym: "mesentery of large bowel" EXACT [OBOL:automatic]
synonym: "mesentery of large intestine" EXACT [FMA:14645]
synonym: "mesocolon" EXACT [https://github.com/obophenotype/uberon/issues/1473]
xref: EMAPA:18942
xref: FMA:14645
xref: SCTID:245457004
is_a: UBERON:0003335 ! serosa of colon
is_a: UBERON:0004854 ! gastrointestinal system mesentery
is_a: UBERON:0007826 {source="FMA"} ! peritoneal mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0001155 ! colon

[Term]
id: UBERON:0003397
name: mesentery of duodenum
namespace: uberon
def: "A mesentery that is part of a duodenum [Automatically generated definition]." [OBOL:automatic]
synonym: "duodenum mesentery" EXACT [OBOL:automatic]
xref: EMAPA:19081
is_a: UBERON:0001170 ! mesentery of small intestine
is_a: UBERON:0003336 ! serosa of duodenum
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0002114 ! duodenum

[Term]
id: UBERON:0003406
name: cartilage of respiratory system
namespace: uberon
def: "A cartilage element that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius cartilage" EXACT [OBOL:automatic]
synonym: "cartilage of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "respiratory system cartilage" EXACT [OBOL:automatic]
xref: EMAPA:18694
xref: MA:0001818
is_a: UBERON:0007844 ! cartilage element
intersection_of: UBERON:0007844 ! cartilage element
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0003408
name: gland of digestive tract
namespace: uberon
def: "A gland that is part of a digestive tract [Automatically generated definition]." [OBOL:automatic]
synonym: "digestive tract gland" EXACT [OBOL:automatic]
synonym: "gland of digestive tract" EXACT [OBOL:automatic]
synonym: "gland of lower gastrointestinal tract" EXACT [OBOL:automatic]
synonym: "gut gland" EXACT [MA:0003202]
synonym: "lower gastrointestinal tract gland" EXACT [OBOL:automatic]
xref: EMAPA:18815
xref: MA:0003202
is_a: UBERON:0002530 ! gland
is_a: UBERON:0013765 ! digestive system element
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0001555 ! digestive tract
relationship: part_of UBERON:0001555 ! digestive tract

[Term]
id: UBERON:0003412
name: pelvic appendage bud mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a pelvic appendage bud." [OBOL:automatic]
synonym: "hindlimb bud mesenchyme" NARROW SENSU [EMAPA:16781]
synonym: "leg mesenchyme" EXACT [OBOL:automatic]
synonym: "lower limb bud mesenchyme" EXACT [EHDAA2:0001035]
synonym: "mesoderm pelvic fin bud" NARROW SENSU [ZFA:0001386]
synonym: "pelvic fin bud mesenchyme" NARROW SENSU []
xref: EHDAA2:0001035
xref: EMAPA:16781
xref: TAO:0001386
xref: ZFA:0001386
is_a: UBERON:0010329 ! paired limb/fin bud mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0005420 ! pelvic appendage bud
relationship: develops_from UBERON:0005730 ! pelvic appendage field
relationship: part_of UBERON:0005420 ! pelvic appendage bud
property_value: UBPROP:0000001 "Mesoderm part of pelvic fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001386", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0003413
name: pectoral appendage bud mesenchyme
namespace: uberon
alt_id: UBERON:0005703
def: "Mesenchyme that is part of a pectoral appendage bud." [OBOL:automatic]
synonym: "arm mesenchyme" NARROW [OBOL:automatic]
synonym: "forelimb bud mesenchyme" NARROW SENSU [EMAPA:16408]
synonym: "mesoderm pectoral fin bud" NARROW SENSU [ZFA:0000789]
synonym: "pectoral fin bud mesenchyme" NARROW SENSU []
synonym: "upper limb bud mesenchyme" NARROW [EHDAA2:0002135]
synonym: "wing mesenchyme" NARROW [OBOL:automatic]
xref: EHDAA2:0002135
xref: EHDAA:1703
xref: EMAPA:16408
xref: TAO:0000789
xref: ZFA:0000789
is_a: UBERON:0010329 ! paired limb/fin bud mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0005419 ! pectoral appendage bud
relationship: develops_from UBERON:0005729 ! pectoral appendage field
relationship: part_of UBERON:0005419 ! pectoral appendage bud
property_value: UBPROP:0000001 "Mesoderm that is part of the pectoral fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000789", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0003422
name: mesenchyme of umbilical cord
namespace: uberon
def: "A gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It also contains some fibroblasts and macrophages. It is derived from Extra Embryonic Mesoderm[WP]." [Wikipedia:Wharton's_jelly]
subset: human_reference_atlas
synonym: "umbilical cord mesenchyme" EXACT [OBOL:automatic]
synonym: "Wharton's jelly" EXACT [EMAPA:26127]
xref: EMAPA:26127
xref: EMAPA:35925
xref: SCTID:368069009
xref: Wikipedia:Wharton's_jelly
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005292 ! extraembryonic tissue
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0002331 ! umbilical cord
relationship: has_part CHEBI:37395 {source="Wikipedia"} ! mucopolysaccharide
relationship: part_of UBERON:0002331 ! umbilical cord
property_value: editor_note "TODO - check" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003426
name: dermis adipose tissue
namespace: uberon
def: "An adipose tissue that is part of a dermis [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "adipose tissue of dermis" EXACT [OBOL:automatic]
synonym: "dermis fat tissue" EXACT [OBOL:automatic]
synonym: "dermis fatty tissue" EXACT [OBOL:automatic]
synonym: "fat tissue of dermis" EXACT [OBOL:automatic]
synonym: "fatty tissue of dermis" EXACT [OBOL:automatic]
xref: MA:0000798
is_a: UBERON:0001013 ! adipose tissue
is_a: UBERON:0003585 ! dermis connective tissue
intersection_of: UBERON:0001013 ! adipose tissue
intersection_of: part_of UBERON:0002067 ! dermis

[Term]
id: UBERON:0003429
name: abdomen nerve
namespace: uberon
def: "A nerve that is part of an abdomen [Automatically generated definition]." [OBOL:automatic]
synonym: "nerve of abdomen" EXACT [OBOL:automatic]
xref: MA:0000521
is_a: UBERON:0003825 ! nerve of abdominal segment
intersection_of: UBERON:0001021 ! nerve
intersection_of: part_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0000916 ! abdomen

[Term]
id: UBERON:0003430
name: neck nerve
namespace: uberon
def: "A nerve that is part of a neck [Automatically generated definition]." [OBOL:automatic]
synonym: "neck (volume) nerve" EXACT [OBOL:automatic]
synonym: "nerve of neck" EXACT [OBOL:automatic]
synonym: "nerve of neck (volume)" EXACT [OBOL:automatic]
xref: EMAPA:37263 {source="MA:th"}
xref: MA:0000588
is_a: UBERON:0001021 ! nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: part_of UBERON:0000974 ! neck
relationship: part_of UBERON:0000974 ! neck

[Term]
id: UBERON:0003438
name: iris nerve
namespace: uberon
def: "Any nerve that innervates the iris." [UBERON:cjm]
synonym: "ciliary nerve" NARROW []
synonym: "nerve of iris" EXACT [OBOL:automatic]
xref: EMAPA:35449
xref: MA:0001291
is_a: UBERON:0001021 ! nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: innervates UBERON:0001769 ! iris
relationship: innervates UBERON:0001769 ! iris
property_value: editor_note "added for consistency with mouse ontologies. The term 'ciliary nerve' is usually used to denote either of the two nerves (with different origins) that innervate the iris, as well as ciliary muscles and cornea" xsd:string

[Term]
id: UBERON:0003439
name: nerve of trunk region
namespace: uberon
def: "A nerve that is part of the trunk region of the body (not to be confused with a nerve trunk)." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
subset: non_informative
synonym: "nerve of torso" EXACT [OBOL:automatic]
synonym: "nerve of trunk" EXACT [OBOL:automatic]
synonym: "torso nerve" EXACT [OBOL:automatic]
synonym: "trunk nerve" RELATED [MA:0000515]
xref: EMAPA:37264 {source="MA:th"}
xref: MA:0000515
is_a: UBERON:0001021 ! nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk

[Term]
id: UBERON:0003443
name: thoracic cavity nerve
namespace: uberon
def: "A nerve that is located in a thoracic cavity [Automatically generated definition]." [OBOL:automatic]
synonym: "cavity of chest nerve" EXACT [OBOL:automatic]
synonym: "cavity of thorax nerve" EXACT [OBOL:automatic]
synonym: "chest cavity nerve" EXACT [OBOL:automatic]
synonym: "nerve of cavity of chest" EXACT [OBOL:automatic]
synonym: "nerve of cavity of thorax" EXACT [OBOL:automatic]
synonym: "nerve of chest cavity" EXACT [OBOL:automatic]
synonym: "nerve of pectoral cavity" EXACT [OBOL:automatic]
synonym: "nerve of thoracic cavity" EXACT [OBOL:automatic]
synonym: "pectoral cavity nerve" EXACT [OBOL:automatic]
xref: EMAPA:37267 {source="MA:th"}
xref: MA:0000556
is_a: UBERON:0001021 ! nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: located_in UBERON:0002224 ! thoracic cavity
relationship: located_in UBERON:0002224 ! thoracic cavity
property_value: editor_note "consider merging with thoracic nerve. In MA the only subclass is the phrenic nerve, which arises from a cervical nerve" xsd:string

[Term]
id: UBERON:0003444
name: pelvis nerve
namespace: uberon
def: "A nerve that is part of a pelvis [Automatically generated definition]." [OBOL:automatic]
synonym: "nerve of pelvis" EXACT [OBOL:automatic]
xref: EMAPA:37269 {source="MA:th"}
xref: MA:0000542
is_a: UBERON:0003825 ! nerve of abdominal segment
intersection_of: UBERON:0001021 ! nerve
intersection_of: part_of UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0002355 ! pelvic region of trunk

[Term]
id: UBERON:0003452
name: trabecula carnea cardiac muscle tissue
namespace: uberon
def: "A portion of cardiac muscle tissue that is part of a trabecula carnea [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "cardiac muscle muscle tissue of trabecula carnea" EXACT [OBOL:automatic]
synonym: "cardiac muscle of trabecula carnea" EXACT [OBOL:automatic]
synonym: "cardiac muscle textus muscularis of trabecula carnea" EXACT [OBOL:automatic]
synonym: "cardiac muscle tissue of trabecula carnea" EXACT [OBOL:automatic]
synonym: "heart muscle muscle tissue of trabecula carnea" EXACT [OBOL:automatic]
synonym: "heart muscle textus muscularis of trabecula carnea" EXACT [OBOL:automatic]
synonym: "heart myocardium muscle tissue of trabecula carnea" EXACT [OBOL:automatic]
synonym: "heart myocardium textus muscularis of trabecula carnea" EXACT [OBOL:automatic]
synonym: "muscle of heart muscle tissue of trabecula carnea" EXACT [OBOL:automatic]
synonym: "muscle of heart textus muscularis of trabecula carnea" EXACT [OBOL:automatic]
synonym: "muscle tissue of cardiac muscle of trabecula carnea" EXACT [OBOL:automatic]
synonym: "muscle tissue of heart muscle of trabecula carnea" EXACT [OBOL:automatic]
synonym: "muscle tissue of heart myocardium of trabecula carnea" EXACT [OBOL:automatic]
synonym: "muscle tissue of muscle of heart of trabecula carnea" EXACT [OBOL:automatic]
synonym: "muscle tissue of myocardium of trabecula carnea" EXACT [OBOL:automatic]
synonym: "myocardium muscle tissue of trabecula carnea" EXACT [OBOL:automatic]
synonym: "myocardium textus muscularis of trabecula carnea" EXACT [OBOL:automatic]
synonym: "textus muscularis of cardiac muscle of trabecula carnea" EXACT [OBOL:automatic]
synonym: "textus muscularis of heart muscle of trabecula carnea" EXACT [OBOL:automatic]
synonym: "textus muscularis of heart myocardium of trabecula carnea" EXACT [OBOL:automatic]
synonym: "textus muscularis of muscle of heart of trabecula carnea" EXACT [OBOL:automatic]
synonym: "textus muscularis of myocardium of trabecula carnea" EXACT [OBOL:automatic]
synonym: "trabecula carnea cardiac muscle" EXACT [OBOL:automatic]
synonym: "trabecula carnea cardiac muscle muscle tissue" EXACT [OBOL:automatic]
synonym: "trabecula carnea cardiac muscle textus muscularis" EXACT [OBOL:automatic]
synonym: "trabecula carnea heart muscle muscle tissue" EXACT [OBOL:automatic]
synonym: "trabecula carnea heart muscle textus muscularis" EXACT [OBOL:automatic]
synonym: "trabecula carnea heart myocardium muscle tissue" EXACT [OBOL:automatic]
synonym: "trabecula carnea heart myocardium textus muscularis" EXACT [OBOL:automatic]
synonym: "trabecula carnea muscle of heart muscle tissue" EXACT [OBOL:automatic]
synonym: "trabecula carnea muscle of heart textus muscularis" EXACT [OBOL:automatic]
synonym: "trabecula carnea muscle tissue of cardiac muscle" EXACT [OBOL:automatic]
synonym: "trabecula carnea muscle tissue of heart muscle" EXACT [OBOL:automatic]
synonym: "trabecula carnea muscle tissue of heart myocardium" EXACT [OBOL:automatic]
synonym: "trabecula carnea muscle tissue of muscle of heart" EXACT [OBOL:automatic]
synonym: "trabecula carnea muscle tissue of myocardium" EXACT [OBOL:automatic]
synonym: "trabecula carnea myocardium muscle tissue" EXACT [OBOL:automatic]
synonym: "trabecula carnea myocardium textus muscularis" EXACT [OBOL:automatic]
synonym: "trabecula carnea textus muscularis of cardiac muscle" EXACT [OBOL:automatic]
synonym: "trabecula carnea textus muscularis of heart muscle" EXACT [OBOL:automatic]
synonym: "trabecula carnea textus muscularis of heart myocardium" EXACT [OBOL:automatic]
synonym: "trabecula carnea textus muscularis of muscle of heart" EXACT [OBOL:automatic]
synonym: "trabecula carnea textus muscularis of myocardium" EXACT [OBOL:automatic]
xref: EMAPA:36573
xref: FMA:84428
xref: MA:0002833
is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002511 ! trabecula carnea
relationship: part_of UBERON:0002511 ! trabecula carnea

[Term]
id: UBERON:0003457
name: head bone
namespace: uberon
def: "A bone that is part of a head [Automatically generated definition]." [OBOL:automatic]
comment: Different sources vary regarding which bones are craniofacial; e.g. hyoid bone
subset: pheno_slim
synonym: "adult head bone" EXACT [OBOL:automatic]
synonym: "adult head bone organ" EXACT [OBOL:automatic]
synonym: "bone of adult head" EXACT [OBOL:automatic]
synonym: "bone of head" EXACT [OBOL:automatic]
synonym: "bone organ of adult head" EXACT [OBOL:automatic]
synonym: "bone organ of head" EXACT [OBOL:automatic]
synonym: "craniofacial bone" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "head bone organ" EXACT [OBOL:automatic]
xref: EMAPA:35996
xref: MA:0000576
xref: SCTID:118646007
is_a: UBERON:0007914 ! bone of craniocervical region
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0000033 ! head

[Term]
id: UBERON:0003458
name: neck bone
namespace: uberon
def: "A bone that is part of a neck [Automatically generated definition]." [OBOL:automatic]
synonym: "bone of neck" EXACT [OBOL:automatic]
synonym: "bone of neck (volume)" EXACT [OBOL:automatic]
synonym: "bone organ of neck" EXACT [OBOL:automatic]
synonym: "bone organ of neck (volume)" EXACT [OBOL:automatic]
synonym: "neck (volume) bone" EXACT [OBOL:automatic]
synonym: "neck (volume) bone organ" EXACT [OBOL:automatic]
synonym: "neck bone organ" EXACT [OBOL:automatic]
xref: EMAPA:37246 {source="MA:th"}
xref: MA:0000584
is_a: UBERON:0001474 ! bone element
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0000974 ! neck
relationship: part_of UBERON:0000974 ! neck

[Term]
id: UBERON:0003462
name: facial bone
namespace: uberon
def: "A bone that is part of a facial skeleton [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "bone of facial skeleton" EXACT [OBOL:automatic]
synonym: "bone of viscerocranium" RELATED [OBOL:automatic]
synonym: "facial bone" EXACT [EMAPA:19019]
synonym: "facial skeleton bone" EXACT [OBOL:automatic]
synonym: "viscerocranium bone" RELATED [OBOL:automatic]
xref: EMAPA:19019
xref: EMAPA:35924
xref: MA:0001482
xref: MA:0003159
xref: MESH:D005147 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C63706
xref: SCTID:181799005
xref: UMLS:C0015455 {source="ncithesaurus:Facial_Bone"}
is_a: UBERON:0003457 ! head bone
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0011156 ! facial skeleton
relationship: part_of UBERON:0011156 {source="MA"} ! facial skeleton
property_value: editor_note "test whether 'facial bone' is an exact synonym" xsd:string

[Term]
id: UBERON:0003463
name: trunk bone
namespace: uberon
def: "A bone that is part of a trunk [Automatically generated definition]." [OBOL:automatic]
synonym: "bone of torso" EXACT [OBOL:automatic]
synonym: "bone of trunk" EXACT [OBOL:automatic]
synonym: "bone organ of torso" EXACT [OBOL:automatic]
synonym: "bone organ of trunk" EXACT [OBOL:automatic]
synonym: "torso bone" EXACT [OBOL:automatic]
synonym: "torso bone organ" EXACT [OBOL:automatic]
synonym: "trunk bone organ" EXACT [OBOL:automatic]
xref: EMAPA:36583
xref: MA:0000512
xref: SCTID:427358002
is_a: UBERON:0001474 ! bone element
is_a: UBERON:0005177 ! trunk region element
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0002100 ! trunk

[Term]
id: UBERON:0003468
name: ureteric segment of renal artery
namespace: uberon
def: "The ureteral branches of renal artery are small branches which supply the ureter." [Wikipedia:Ureteral_branches_of_renal_artery]
subset: human_reference_atlas
synonym: "ureteric artery" BROAD [MA:0002074]
xref: EMAPA:37676 {source="MA:th"}
xref: FMA:70491
xref: MA:0002074
xref: SCTID:65376008
xref: Wikipedia:Ureteral_branches_of_renal_artery
is_a: UBERON:0004573 ! systemic artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0000056 ! ureter
relationship: connecting_branch_of UBERON:0001184 {source="FMA"} ! renal artery
relationship: part_of UBERON:0001184 {source="FMA"} ! renal artery
relationship: supplies UBERON:0000056 ! ureter
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003469
name: respiratory system artery
namespace: uberon
def: "An artery that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:37569 {source="MA:th"}
xref: MA:0001804
is_a: UBERON:0001637 ! artery
is_a: UBERON:0003643 ! respiratory system arterial blood vessel
intersection_of: UBERON:0001637 ! artery
intersection_of: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0003470
name: artery of upper lip
namespace: uberon
def: "The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose." [Wikipedia:Superior_labial_artery]
subset: human_reference_atlas
synonym: "arteria labialis superior" EXACT OMO:0003011 [Wikipedia:Superior_labial_artery]
synonym: "ramus labialis superior arteriae facialis" EXACT OMO:0003011 [Wikipedia:Superior_labial_artery]
synonym: "superior labial artery" EXACT [FMA:49570]
synonym: "superior labial branch of facial artery" EXACT [FMA:49570]
xref: EMAPA:37430 {source="MA:th"}
xref: FMA:49570
xref: MA:0001917
xref: SCTID:145137009
xref: Wikipedia:Superior_labial_artery
is_a: UBERON:0003496 ! head blood vessel
is_a: UBERON:0009657 ! artery of lip
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001834 ! upper lip
relationship: connecting_branch_of UBERON:0001612 {source="FMA"} ! facial artery
relationship: supplies UBERON:0001834 ! upper lip
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003471
name: artery of lower lip
namespace: uberon
def: "The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery." [Wikipedia:Inferior_labial_artery]
subset: human_reference_atlas
synonym: "arteria labialis inferior" EXACT OMO:0003011 [Wikipedia:Inferior_labial_artery]
synonym: "inferior labial artery" EXACT [FMA:49567]
synonym: "inferior labial branch of facial artery" EXACT [FMA:49567]
synonym: "ramus labialis inferior (arteria facialis)" EXACT [FMA:TA]
synonym: "ramus labialis inferior arteriae facialis" EXACT OMO:0003011 [Wikipedia:Inferior_labial_artery]
xref: EMAPA:37429 {source="MA:th"}
xref: FMA:49567
xref: MA:0001916
xref: SCTID:145036002
xref: Wikipedia:Inferior_labial_artery
is_a: UBERON:0003496 ! head blood vessel
is_a: UBERON:0009657 ! artery of lip
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001835 ! lower lip
relationship: connecting_branch_of UBERON:0001612 {source="FMA"} ! facial artery
relationship: supplies UBERON:0001835 ! lower lip
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003473
name: thoracic cavity artery
namespace: uberon
def: "An artery that is part of a thoracic cavity[cjm]." [https://sourceforge.net/tracker/index.php?func=detail&aid=3317815&group_id=76834&atid=1205376]
synonym: "thoracic artery" RELATED [MESH:A07.231.114.891]
xref: EMAPA:37241 {source="MA:th"}
xref: MA:0001902
xref: MESH:D013895
is_a: UBERON:0001637 ! artery
is_a: UBERON:0003519 ! thoracic cavity blood vessel
intersection_of: UBERON:0001637 ! artery
intersection_of: located_in UBERON:0002224 ! thoracic cavity
property_value: UBPROP:0000012 "in MA, aorta is classified here - but this is problematic because the abdominal aorta is not in the thoracic cavity" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0003475
name: ureteric vein
namespace: uberon
def: "A vein that is part of a ureter [Automatically generated definition]." [OBOL:automatic]
synonym: "ureter vein" EXACT [OBOL:automatic]
synonym: "vein of ureter" EXACT [OBOL:automatic]
xref: EMAPA:37679 {source="MA:th"}
xref: MA:0002250
is_a: UBERON:0001638 ! vein
is_a: UBERON:0003520 ! pelvis blood vessel
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0000056 ! ureter
relationship: part_of UBERON:0000056 ! ureter

[Term]
id: UBERON:0003476
name: respiratory system venous blood vessel
namespace: uberon
def: "A vein that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius vein" EXACT [OBOL:automatic]
synonym: "respiratory system vein" EXACT [OBOL:automatic]
synonym: "vein of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "vein of respiratory system" EXACT [OBOL:automatic]
xref: EMAPA:37584 {source="MA:th"}
xref: MA:0001809
xref: MA:0001810
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0001004 ! respiratory system
relationship: drains UBERON:0001004 ! respiratory system
relationship: part_of RO:0002577 ! system

[Term]
id: UBERON:0003477
name: vein of upper lip
namespace: uberon
def: "The inferior labial vein is the vein receiving blood from the upper lip." [Wikipedia:Superior_labial_vein]
subset: human_reference_atlas
synonym: "superior labial vein" EXACT [FMA:52538]
synonym: "upper lip vein" EXACT [OBOL:automatic]
synonym: "vena labialis superior" EXACT OMO:0003011 []
xref: EMAPA:37204 {source="MA:th"}
xref: FMA:52538
xref: MA:0002255
xref: SCTID:422755007
xref: Wikipedia:Superior_labial_vein
is_a: UBERON:0013136 ! vein of lip
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0001834 ! upper lip
relationship: drains UBERON:0001834 ! upper lip
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003478
name: vein of lower lip
namespace: uberon
def: "The inferior labial vein is the vein receiving blood from the lower lip." [Wikipedia:Inferior_labial_vein]
subset: human_reference_atlas
synonym: "inferior labial vein" EXACT [FMA:52541]
synonym: "lower lip vein" EXACT [OBOL:automatic]
synonym: "vena labialis inferior" EXACT OMO:0003011 []
synonym: "venae labiales inferiores" RELATED OMO:0003011 [Wikipedia:Inferior_labial_vein]
xref: EMAPA:37202 {source="MA:th"}
xref: FMA:52541
xref: MA:0002253
xref: SCTID:422955002
xref: Wikipedia:Inferior_labial_vein
is_a: UBERON:0013136 ! vein of lip
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0001835 ! lower lip
relationship: drains UBERON:0001835 ! lower lip
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003479
name: thoracic cavity vein
namespace: uberon
def: "A vein that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic]
synonym: "cavity of chest vein" EXACT [OBOL:automatic]
synonym: "cavity of thorax vein" EXACT [OBOL:automatic]
synonym: "chest cavity vein" EXACT [OBOL:automatic]
synonym: "pectoral cavity vein" EXACT [OBOL:automatic]
synonym: "vein of cavity of chest" EXACT [OBOL:automatic]
synonym: "vein of cavity of thorax" EXACT [OBOL:automatic]
synonym: "vein of chest cavity" EXACT [OBOL:automatic]
synonym: "vein of pectoral cavity" EXACT [OBOL:automatic]
synonym: "vein of thoracic cavity" EXACT [OBOL:automatic]
xref: EMAPA:37242 {source="MA:th"}
xref: MA:0001903
is_a: UBERON:0001638 ! vein
is_a: UBERON:0003519 ! thoracic cavity blood vessel
intersection_of: UBERON:0001638 ! vein
intersection_of: located_in UBERON:0002224 ! thoracic cavity

[Term]
id: UBERON:0003480
name: vein of clitoris
namespace: uberon
def: "A vein that is part of a clitoris [Automatically generated definition]." [OBOL:automatic]
synonym: "clitoris vein" EXACT [OBOL:automatic]
xref: EMAPA:37201 {source="MA:th"}
xref: MA:0002252
xref: SCTID:360819004
is_a: UBERON:0001638 ! vein
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0002411 ! clitoris
relationship: part_of UBERON:0002411 ! clitoris

[Term]
id: UBERON:0003481
name: tail vein
namespace: uberon
def: "A vein that is part of a tail [Automatically generated definition]." [OBOL:automatic, Wikipedia:Tail_vein]
synonym: "caudal vein" RELATED [Wikipedia:Tail_vein]
synonym: "post-vent region vein" EXACT [OBOL:automatic]
synonym: "vein of post-vent region" EXACT [OBOL:automatic]
synonym: "vein of tail" EXACT [OBOL:automatic]
xref: AAO:0011105
xref: EMAPA:37761 {source="MA:th"}
xref: MA:0002233
xref: Wikipedia:Tail_vein
xref: XAO:0000393
is_a: UBERON:0001638 ! vein
is_a: UBERON:0003524 ! tail blood vessel
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0007812 ! post-anal tail
property_value: editor_note "see also caudal vein" xsd:string

[Term]
id: UBERON:0003489
name: respiratory system capillary endothelium
namespace: uberon
def: "An endothelium of capillary that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius blood capillary endothelium" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius capillary endothelium" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius capillary vessel endothelium" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius endothelium of blood capillary" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius endothelium of capillary" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius endothelium of capillary vessel" EXACT [OBOL:automatic]
synonym: "blood capillary endothelium of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "blood capillary endothelium of respiratory system" EXACT [OBOL:automatic]
synonym: "capillary endothelium of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "capillary endothelium of respiratory system" EXACT [OBOL:automatic]
synonym: "capillary vessel endothelium of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "capillary vessel endothelium of respiratory system" EXACT [OBOL:automatic]
synonym: "endothelium of blood capillary of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "endothelium of blood capillary of respiratory system" EXACT [OBOL:automatic]
synonym: "endothelium of capillary of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "endothelium of capillary of respiratory system" EXACT [OBOL:automatic]
synonym: "endothelium of capillary vessel of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "endothelium of capillary vessel of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory system blood capillary endothelium" EXACT [OBOL:automatic]
synonym: "respiratory system capillary vessel endothelium" EXACT [OBOL:automatic]
synonym: "respiratory system endothelium of blood capillary" EXACT [OBOL:automatic]
synonym: "respiratory system endothelium of capillary" EXACT [OBOL:automatic]
synonym: "respiratory system endothelium of capillary vessel" EXACT [OBOL:automatic]
xref: EMAPA:37575 {source="MA:th"}
xref: MA:0001808
is_a: UBERON:0001915 ! endothelium of capillary
is_a: UBERON:0004702 ! respiratory system blood vessel endothelium
intersection_of: UBERON:0001915 ! endothelium of capillary
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0003526 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! respiratory system capillary

[Term]
id: UBERON:0003494
name: respiratory system venule
namespace: uberon
def: "A venule that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius venule" EXACT [OBOL:automatic]
synonym: "venule of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "venule of respiratory system" EXACT [OBOL:automatic]
xref: EMAPA:37587 {source="MA:th"}
xref: MA:0001813
is_a: UBERON:0001979 ! venule
is_a: UBERON:0003504 ! respiratory system blood vessel
intersection_of: UBERON:0001979 ! venule
intersection_of: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0003495
name: respiratory system arteriole
namespace: uberon
def: "An arteriole that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:37568 {source="MA:th"}
xref: MA:0001803
is_a: UBERON:0001980 ! arteriole
is_a: UBERON:0003643 ! respiratory system arterial blood vessel
intersection_of: UBERON:0001980 ! arteriole
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0003469 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! respiratory system artery

[Term]
id: UBERON:0003496
name: head blood vessel
namespace: uberon
def: "A blood vessel that is part of a head [Automatically generated definition]." [OBOL:automatic]
synonym: "adult head blood vessel" EXACT [OBOL:automatic]
synonym: "blood vessel of adult head" EXACT [OBOL:automatic]
synonym: "blood vessel of head" EXACT [OBOL:automatic]
xref: EMAPA:36610
xref: MA:0000575
xref: SCTID:127865000
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0011362 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! cranial blood vasculature

[Term]
id: UBERON:0003497
name: abdomen blood vessel
namespace: uberon
def: "A blood vessel that is part of an abdomen [Automatically generated definition]." [OBOL:automatic]
synonym: "blood vessel of abdomen" EXACT [OBOL:automatic]
xref: MA:0000518
is_a: UBERON:0003835 ! abdominal segment blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0000916 ! abdomen
property_value: seeAlso "UBERON:0012254" xsd:string {notes="abdominal aorta artery"}

[Term]
id: UBERON:0003498
name: heart blood vessel
namespace: uberon
def: "A blood vessel that is part of a heart [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "blood vessel of heart" EXACT [OBOL:automatic]
synonym: "cardiac blood vessel" RELATED [EMAPA:35397]
xref: EMAPA:35397
xref: MA:0002483
is_a: UBERON:0003834 ! thoracic segment blood vessel
is_a: UBERON:0005985 ! coronary vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0000948 ! heart
relationship: part_of UBERON:0018674 ! heart vasculature

[Term]
id: UBERON:0003499
name: brain blood vessel
namespace: uberon
def: "A blood vessel that is part of a brain [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "blood vessel of brain" EXACT [OBOL:automatic]
xref: EMAPA:35182
xref: MA:0002769
is_a: UBERON:0001981 ! blood vessel
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0000955 ! brain
relationship: part_of UBERON:0008998 ! vasculature of brain

[Term]
id: UBERON:0003500
name: corneal blood vessel
namespace: uberon
def: "A blood vessel that is part of a cornea [Automatically generated definition]." [https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/index.php?func=detail&aid=3564332&group_id=36855&atid=440764]
synonym: "blood vessel of cornea" EXACT [OBOL:automatic]
synonym: "cornea blood vessel" EXACT [OBOL:automatic]
xref: EMAPA:36611
xref: MA:0001241
is_a: UBERON:0003496 ! head blood vessel
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0000964 ! cornea
relationship: part_of UBERON:0000964 ! cornea
property_value: editor_note "follow up on tracker item" xsd:string
property_value: RO:0002175 NCBITaxon:9775 {source="PMID:17051153"}

[Term]
id: UBERON:0003501
name: retina blood vessel
namespace: uberon
def: "A blood vessel that is part of a retina [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "blood vessel of inner layer of eyeball" EXACT [OBOL:automatic]
synonym: "blood vessel of retina" EXACT [OBOL:automatic]
synonym: "blood vessel of tunica interna of eyeball" EXACT [OBOL:automatic]
synonym: "inner layer of eyeball blood vessel" EXACT [OBOL:automatic]
synonym: "retinal blood vessel" EXACT [OBOL:automatic]
synonym: "tunica interna of eyeball blood vessel" EXACT [OBOL:automatic]
xref: EMAPA:36520
xref: GAID:509
xref: MA:0001317
xref: MESH:D012171
xref: SCTID:280692003
xref: XAO:0004153
is_a: UBERON:0003496 ! head blood vessel
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0000966 ! retina
relationship: contributes_to_morphology_of UBERON:0000966 ! retina
relationship: part_of UBERON:0004864 ! vasculature of retina

[Term]
id: UBERON:0003502
name: neck blood vessel
namespace: uberon
def: "A blood vessel that is part of a neck [Automatically generated definition]." [OBOL:automatic]
synonym: "blood vessel of neck" EXACT [OBOL:automatic]
synonym: "blood vessel of neck (volume)" EXACT [OBOL:automatic]
synonym: "neck (volume) blood vessel" EXACT [OBOL:automatic]
xref: EMAPA:37236 {source="MA:th"}
xref: MA:0000583
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0000974 ! neck
relationship: part_of UBERON:0000974 ! neck

[Term]
id: UBERON:0003504
name: respiratory system blood vessel
namespace: uberon
def: "A blood vessel that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius blood vessel" EXACT [OBOL:automatic]
synonym: "blood vessel of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "blood vessel of respiratory system" EXACT [OBOL:automatic]
xref: EMAPA:35731
xref: EMAPA:35995
xref: MA:0001799
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0003509
name: arterial blood vessel
namespace: uberon
def: "A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta." [https://orcid.org/0000-0002-6601-2165]
comment: only in MA - supertype of artery, arteriole, aorta.
subset: pheno_slim
xref: EMAPA:35144
xref: MA:0000061
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0004572 ! arterial system
relationship: part_of UBERON:0004572 ! arterial system

[Term]
id: UBERON:0003511
name: iris blood vessel
namespace: uberon
def: "A blood vessel that is part of a iris [Automatically generated definition]." [OBOL:automatic]
subset: vertebrate_core
synonym: "blood vessel of iris" EXACT [OBOL:automatic]
xref: EMAPA:37387 {source="MA:th"}
xref: MA:0001290
xref: ZFA:0005568
is_a: UBERON:0003496 ! head blood vessel
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0001769 ! iris
relationship: part_of UBERON:0004118 ! vasculature of iris

[Term]
id: UBERON:0003512
name: lung blood vessel
namespace: uberon
def: "A blood vessel that is part of a lung [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "blood vessel of lung" EXACT [OBOL:automatic]
synonym: "pulmonary vascular element" RELATED [EMAPA:32867]
xref: EMAPA:32867
xref: MA:0002457
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0003504 ! respiratory system blood vessel
is_a: UBERON:0003834 ! thoracic segment blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0002048 ! lung
relationship: contributes_to_morphology_of UBERON:0002048 ! lung
relationship: part_of UBERON:0002048 ! lung

[Term]
id: UBERON:0003513
name: trunk blood vessel
namespace: uberon
def: "A blood vessel that is part of a trunk [Automatically generated definition]." [OBOL:automatic]
synonym: "blood vessel of torso" EXACT [OBOL:automatic]
synonym: "blood vessel of trunk" EXACT [OBOL:automatic]
synonym: "torso blood vessel" EXACT [OBOL:automatic]
xref: EMAPA:37237 {source="MA:th"}
xref: MA:0000511
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk

[Term]
id: UBERON:0003517
name: kidney blood vessel
namespace: uberon
def: "A blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
subset: pheno_slim
subset: vertebrate_core
synonym: "blood vessel of kidney" EXACT [OBOL:automatic]
synonym: "renal blood vessel" EXACT [OBOL:automatic]
xref: EMAPA:28457
xref: MA:0001682
xref: TAO:0005306
xref: ZFA:0005306
is_a: UBERON:0003497 ! abdomen blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0006544 ! kidney vasculature
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003519
name: thoracic cavity blood vessel
namespace: uberon
def: "A blood vessel that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic]
synonym: "blood vessel of cavity of chest" EXACT [OBOL:automatic]
synonym: "blood vessel of cavity of thorax" EXACT [OBOL:automatic]
synonym: "blood vessel of chest cavity" EXACT [OBOL:automatic]
synonym: "blood vessel of pectoral cavity" EXACT [OBOL:automatic]
synonym: "blood vessel of thoracic cavity" EXACT [OBOL:automatic]
synonym: "cavity of chest blood vessel" EXACT [OBOL:automatic]
synonym: "cavity of thorax blood vessel" EXACT [OBOL:automatic]
synonym: "chest cavity blood vessel" EXACT [OBOL:automatic]
synonym: "pectoral cavity blood vessel" EXACT [OBOL:automatic]
xref: EMAPA:37240 {source="MA:th"}
xref: MA:0000554
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: located_in UBERON:0002224 ! thoracic cavity
relationship: located_in UBERON:0002224 ! thoracic cavity

[Term]
id: UBERON:0003520
name: pelvis blood vessel
namespace: uberon
def: "A blood vessel that is part of a pelvis [Automatically generated definition]." [OBOL:automatic]
synonym: "blood vessel of pelvis" EXACT [OBOL:automatic]
xref: EMAPA:37244 {source="MA:th"}
xref: MA:0000531
is_a: UBERON:0003835 ! abdominal segment blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0002355 ! pelvic region of trunk

[Term]
id: UBERON:0003524
name: tail blood vessel
namespace: uberon
def: "A blood vessel that is part of a tail [Automatically generated definition]." [OBOL:automatic]
synonym: "blood vessel of post-vent region" EXACT [OBOL:automatic]
synonym: "blood vessel of tail" EXACT [OBOL:automatic]
synonym: "post-vent region blood vessel" EXACT [OBOL:automatic]
xref: EMAPA:35848
xref: MA:0000695
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0007812 ! post-anal tail
relationship: part_of UBERON:0007812 ! post-anal tail

[Term]
id: UBERON:0003526
name: respiratory system capillary
namespace: uberon
def: "A capillary that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius blood capillary" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius capillary" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius capillary vessel" EXACT [OBOL:automatic]
synonym: "blood capillary of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "blood capillary of respiratory system" EXACT [OBOL:automatic]
synonym: "capillary of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "capillary of respiratory system" EXACT [OBOL:automatic]
synonym: "capillary vessel of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "capillary vessel of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory system blood capillary" EXACT [OBOL:automatic]
synonym: "respiratory system capillary vessel" EXACT [OBOL:automatic]
xref: EMAPA:37574 {source="MA:th"}
xref: MA:0001807
is_a: UBERON:0001982 ! capillary
is_a: UBERON:0003504 ! respiratory system blood vessel
intersection_of: UBERON:0001982 ! capillary
intersection_of: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0003527
name: kidney capillary
namespace: uberon
def: "A capillary that is part of a kidney [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
subset: pheno_slim
synonym: "blood capillary of kidney" EXACT [OBOL:automatic]
synonym: "capillary of kidney" EXACT [OBOL:automatic]
synonym: "capillary vessel of kidney" EXACT [OBOL:automatic]
synonym: "kidney blood capillary" EXACT [OBOL:automatic]
synonym: "kidney capillary vessel" EXACT [OBOL:automatic]
synonym: "renal capillary" EXACT [OBOL:automatic]
xref: EMAPA:31443
xref: MA:0002586
xref: SCTID:275409003
is_a: UBERON:0001982 ! capillary
is_a: UBERON:0003517 ! kidney blood vessel
intersection_of: UBERON:0001982 ! capillary
intersection_of: part_of UBERON:0002113 ! kidney
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003528
name: brain gray matter
namespace: uberon
def: "A gray matter that is part of a brain [Automatically generated definition]." [OBOL:automatic]
synonym: "brain grey matter" EXACT [MA:0000810]
synonym: "brain grey substance" EXACT [OBOL:automatic]
synonym: "gray matter of brain" EXACT [OBOL:automatic]
synonym: "grey matter of brain" EXACT [OBOL:automatic]
synonym: "grey substance of brain" EXACT [OBOL:automatic]
xref: EMAPA:35184
xref: MA:0000810
xref: NCIT:C49333
xref: UMLS:C1707348 {source="ncithesaurus:Cerebral_Gray_Matter"}
is_a: UBERON:0002020 ! gray matter
intersection_of: UBERON:0002020 ! gray matter
intersection_of: part_of UBERON:0000955 ! brain
relationship: part_of UBERON:0000955 ! brain

[Term]
id: UBERON:0003534
name: tail skin
namespace: uberon
def: "A zone of skin that is part of a tail [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "post-vent region skin" EXACT [OBOL:automatic]
synonym: "skin of post-vent region" EXACT [OBOL:automatic]
synonym: "skin of tail" EXACT [OBOL:automatic]
xref: EMAPA:36502
xref: MA:0000700
xref: SCTID:67214004
is_a: UBERON:0000014 ! zone of skin
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0007812 ! post-anal tail
relationship: part_of UBERON:0007812 ! post-anal tail

[Term]
id: UBERON:0003566
name: head connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a head [Automatically generated definition]." [OBOL:automatic]
synonym: "adult head connective tissue" EXACT [OBOL:automatic]
synonym: "adult head portion of connective tissue" EXACT [OBOL:automatic]
synonym: "adult head textus connectivus" EXACT [OBOL:automatic]
synonym: "connective tissue of adult head" EXACT [OBOL:automatic]
synonym: "connective tissue of head" EXACT [OBOL:automatic]
synonym: "head portion of connective tissue" EXACT [OBOL:automatic]
synonym: "head textus connectivus" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of adult head" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of head" EXACT [OBOL:automatic]
synonym: "textus connectivus of adult head" EXACT [OBOL:automatic]
synonym: "textus connectivus of head" EXACT [OBOL:automatic]
xref: EMAPA:16098
xref: MA:0000577
is_a: UBERON:0002384 ! connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0000033 ! head
relationship: develops_from UBERON:0005253 ! head mesenchyme
relationship: part_of UBERON:0000033 ! head
relationship: transformation_of UBERON:0005253 ! head mesenchyme

[Term]
id: UBERON:0003567
name: abdomen connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of an abdomen [Automatically generated definition]." [OBOL:automatic]
synonym: "abdomen portion of connective tissue" EXACT [OBOL:automatic]
synonym: "abdomen textus connectivus" EXACT [OBOL:automatic]
synonym: "connective tissue of abdomen" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of abdomen" EXACT [OBOL:automatic]
synonym: "textus connectivus of abdomen" EXACT [OBOL:automatic]
xref: MA:0000519
is_a: UBERON:0003838 ! abdominal segment connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0000916 ! abdomen

[Term]
id: UBERON:0003568
name: neck connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a neck [Automatically generated definition]." [OBOL:automatic]
synonym: "connective tissue of neck" EXACT [OBOL:automatic]
synonym: "connective tissue of neck (volume)" EXACT [OBOL:automatic]
synonym: "neck (volume) connective tissue" EXACT [OBOL:automatic]
synonym: "neck (volume) portion of connective tissue" EXACT [OBOL:automatic]
synonym: "neck (volume) textus connectivus" EXACT [OBOL:automatic]
synonym: "neck portion of connective tissue" EXACT [OBOL:automatic]
synonym: "neck textus connectivus" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of neck" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of neck (volume)" EXACT [OBOL:automatic]
synonym: "textus connectivus of neck" EXACT [OBOL:automatic]
synonym: "textus connectivus of neck (volume)" EXACT [OBOL:automatic]
xref: EMAPA:37250 {source="MA:th"}
xref: MA:0000585
is_a: UBERON:0002384 ! connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0000974 ! neck
relationship: part_of UBERON:0000974 ! neck

[Term]
id: UBERON:0003570
name: respiratory system connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius connective tissue" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius portion of connective tissue" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius textus connectivus" EXACT [OBOL:automatic]
synonym: "connective tissue of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "connective tissue of respiratory system" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory system portion of connective tissue" EXACT [OBOL:automatic]
synonym: "respiratory system textus connectivus" EXACT [OBOL:automatic]
synonym: "textus connectivus of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "textus connectivus of respiratory system" EXACT [OBOL:automatic]
xref: EMAPA:35968
xref: EMAPA:35977
xref: MA:0001814
is_a: UBERON:0002384 ! connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0003580
name: lower respiratory tract connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic]
synonym: "connective tissue of lower respiratory tract" EXACT [OBOL:automatic]
synonym: "lower respiratory tract portion of connective tissue" EXACT [OBOL:automatic]
synonym: "lower respiratory tract textus connectivus" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of lower respiratory tract" EXACT [OBOL:automatic]
synonym: "textus connectivus of lower respiratory tract" EXACT [OBOL:automatic]
xref: EMAPA:37548 {source="MA:th"}
xref: MA:0002409
is_a: UBERON:0003570 ! respiratory system connective tissue
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0001558 ! lower respiratory tract
relationship: part_of UBERON:0001558 ! lower respiratory tract

[Term]
id: UBERON:0003585
name: dermis connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a dermis [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "connective tissue of dermis" EXACT [OBOL:automatic]
synonym: "dermis portion of connective tissue" EXACT [OBOL:automatic]
synonym: "dermis textus connectivus" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of dermis" EXACT [OBOL:automatic]
synonym: "textus connectivus of dermis" EXACT [OBOL:automatic]
xref: EMAPA:36509
xref: MA:0000799
is_a: UBERON:0002384 ! connective tissue
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0002067 ! dermis
relationship: develops_from UBERON:0004016 ! dermatome
relationship: part_of UBERON:0002067 ! dermis

[Term]
id: UBERON:0003586
name: trunk connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a trunk [Automatically generated definition]." [OBOL:automatic]
synonym: "connective tissue of torso" EXACT [OBOL:automatic]
synonym: "connective tissue of trunk" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of torso" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of trunk" EXACT [OBOL:automatic]
synonym: "textus connectivus of torso" EXACT [OBOL:automatic]
synonym: "textus connectivus of trunk" EXACT [OBOL:automatic]
synonym: "torso connective tissue" EXACT [OBOL:automatic]
synonym: "torso portion of connective tissue" EXACT [OBOL:automatic]
synonym: "torso textus connectivus" EXACT [OBOL:automatic]
synonym: "trunk portion of connective tissue" EXACT [OBOL:automatic]
synonym: "trunk textus connectivus" EXACT [OBOL:automatic]
xref: EMAPA:37252 {source="MA:th"}
xref: MA:0000513
is_a: UBERON:0002384 ! connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk

[Term]
id: UBERON:0003593
name: thoracic cavity connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic]
synonym: "cavity of chest connective tissue" EXACT [OBOL:automatic]
synonym: "cavity of chest portion of connective tissue" EXACT [OBOL:automatic]
synonym: "cavity of chest textus connectivus" EXACT [OBOL:automatic]
synonym: "cavity of thorax connective tissue" EXACT [OBOL:automatic]
synonym: "cavity of thorax portion of connective tissue" EXACT [OBOL:automatic]
synonym: "cavity of thorax textus connectivus" EXACT [OBOL:automatic]
synonym: "chest cavity connective tissue" EXACT [OBOL:automatic]
synonym: "chest cavity portion of connective tissue" EXACT [OBOL:automatic]
synonym: "chest cavity textus connectivus" EXACT [OBOL:automatic]
synonym: "connective tissue of cavity of chest" EXACT [OBOL:automatic]
synonym: "connective tissue of cavity of thorax" EXACT [OBOL:automatic]
synonym: "connective tissue of chest cavity" EXACT [OBOL:automatic]
synonym: "connective tissue of pectoral cavity" EXACT [OBOL:automatic]
synonym: "connective tissue of thoracic cavity" EXACT [OBOL:automatic]
synonym: "pectoral cavity connective tissue" EXACT [OBOL:automatic]
synonym: "pectoral cavity portion of connective tissue" EXACT [OBOL:automatic]
synonym: "pectoral cavity textus connectivus" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of cavity of chest" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of cavity of thorax" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of chest cavity" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of pectoral cavity" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of thoracic cavity" EXACT [OBOL:automatic]
synonym: "textus connectivus of cavity of chest" EXACT [OBOL:automatic]
synonym: "textus connectivus of cavity of thorax" EXACT [OBOL:automatic]
synonym: "textus connectivus of chest cavity" EXACT [OBOL:automatic]
synonym: "textus connectivus of pectoral cavity" EXACT [OBOL:automatic]
synonym: "textus connectivus of thoracic cavity" EXACT [OBOL:automatic]
synonym: "thoracic cavity portion of connective tissue" EXACT [OBOL:automatic]
synonym: "thoracic cavity textus connectivus" EXACT [OBOL:automatic]
xref: EMAPA:37255 {source="MA:th"}
xref: MA:0000555
is_a: UBERON:0002384 ! connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: located_in UBERON:0002224 ! thoracic cavity
relationship: located_in UBERON:0002224 ! thoracic cavity

[Term]
id: UBERON:0003594
name: pelvis connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a pelvis [Automatically generated definition]." [OBOL:automatic]
synonym: "connective tissue of pelvis" EXACT [OBOL:automatic]
synonym: "pelvis portion of connective tissue" EXACT [OBOL:automatic]
synonym: "pelvis textus connectivus" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of pelvis" EXACT [OBOL:automatic]
synonym: "textus connectivus of pelvis" EXACT [OBOL:automatic]
xref: EMAPA:37257 {source="MA:th"}
xref: MA:0000533
is_a: UBERON:0003838 ! abdominal segment connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0002355 ! pelvic region of trunk

[Term]
id: UBERON:0003599
name: tail connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a tail [Automatically generated definition]." [OBOL:automatic]
synonym: "connective tissue of post-vent region" EXACT [OBOL:automatic]
synonym: "connective tissue of tail" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of post-vent region" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of tail" EXACT [OBOL:automatic]
synonym: "post-vent region connective tissue" EXACT [OBOL:automatic]
synonym: "post-vent region portion of connective tissue" EXACT [OBOL:automatic]
synonym: "post-vent region textus connectivus" EXACT [OBOL:automatic]
synonym: "tail portion of connective tissue" EXACT [OBOL:automatic]
synonym: "tail textus connectivus" EXACT [OBOL:automatic]
synonym: "textus connectivus of post-vent region" EXACT [OBOL:automatic]
synonym: "textus connectivus of tail" EXACT [OBOL:automatic]
xref: EMAPA:16749
xref: MA:0000697
is_a: UBERON:0002384 ! connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0007812 ! post-anal tail
relationship: part_of UBERON:0007812 ! post-anal tail

[Term]
id: UBERON:0003601
name: neck cartilage
namespace: uberon
def: "A cartilage that is part of a neck [Automatically generated definition]." [OBOL:automatic]
synonym: "cartilage of neck" EXACT [OBOL:automatic]
synonym: "cartilage of neck (volume)" EXACT [OBOL:automatic]
synonym: "neck (volume) cartilage" EXACT [OBOL:automatic]
xref: EMAPA:37251 {source="MA:th"}
xref: MA:0000586
is_a: UBERON:0007844 ! cartilage element
intersection_of: UBERON:0007844 ! cartilage element
intersection_of: part_of UBERON:0000974 ! neck
relationship: part_of UBERON:0000974 ! neck

[Term]
id: UBERON:0003603
name: lower respiratory tract cartilage
namespace: uberon
def: "A cartilage that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic]
synonym: "cartilage of lower respiratory tract" EXACT [OBOL:automatic]
xref: EMAPA:37547 {source="MA:th"}
xref: MA:0001819
xref: NCIT:C49256
xref: UMLS:C1708759 {source="ncithesaurus:Lower_Respiratory_Tract_Cartilage"}
is_a: UBERON:0003406 ! cartilage of respiratory system
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0007844 ! cartilage element
intersection_of: part_of UBERON:0001558 ! lower respiratory tract
relationship: part_of UBERON:0001558 ! lower respiratory tract

[Term]
id: UBERON:0003605
name: eye skin gland
namespace: uberon
def: "A skin gland that is part of a camera-type eye [Automatically generated definition]." [OBOL:automatic]
subset: organ_slim
synonym: "camera-type eye skin gland" EXACT [OBOL:automatic]
synonym: "camera-type eye skin glands" EXACT [OBOL:automatic]
synonym: "camera-type eye skin glands set" EXACT [OBOL:automatic]
synonym: "skin gland of camera-type eye" EXACT [OBOL:automatic]
synonym: "skin gland of vertebrate eye" EXACT [OBOL:automatic]
synonym: "skin glands of camera-type eye" EXACT [OBOL:automatic]
synonym: "skin glands of vertebrate eye" EXACT [OBOL:automatic]
synonym: "skin glands set of camera-type eye" EXACT [OBOL:automatic]
synonym: "skin glands set of vertebrate eye" EXACT [OBOL:automatic]
synonym: "vertebrate eye skin gland" EXACT [OBOL:automatic]
synonym: "vertebrate eye skin glands" EXACT [OBOL:automatic]
synonym: "vertebrate eye skin glands set" EXACT [OBOL:automatic]
xref: EMAPA:37530 {source="MA:th"}
xref: MA:0002451
is_a: UBERON:0002419 ! skin gland
is_a: UBERON:0004859 ! eye gland
is_a: UBERON:0015152 ! gland of ocular region
intersection_of: UBERON:0002419 ! skin gland
intersection_of: part_of UBERON:0000019 ! camera-type eye
relationship: part_of UBERON:0000019 ! camera-type eye

[Term]
id: UBERON:0003609
name: aorta elastic tissue
namespace: uberon
def: "The dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall." [MP:0009862]
subset: pheno_slim
synonym: "adult aorta elastic connective tissue" EXACT [OBOL:automatic]
synonym: "adult aorta elastic tissue" EXACT [OBOL:automatic]
synonym: "adult aorta textus connectivus elasticus" EXACT [OBOL:automatic]
synonym: "aorta elastic connective tissue" EXACT [OBOL:automatic]
synonym: "aorta elastic lamina" EXACT [MP:0009862]
synonym: "aorta elastic laminae" EXACT OMO:0003004 [MP:0009862]
synonym: "aorta textus connectivus elasticus" EXACT [OBOL:automatic]
synonym: "dorsal aorta elastic connective tissue" EXACT [OBOL:automatic]
synonym: "dorsal aorta elastic tissue" EXACT [OBOL:automatic]
synonym: "dorsal aorta textus connectivus elasticus" EXACT [OBOL:automatic]
synonym: "elastic connective tissue of adult aorta" EXACT [OBOL:automatic]
synonym: "elastic connective tissue of aorta" EXACT [OBOL:automatic]
synonym: "elastic connective tissue of dorsal aorta" EXACT [OBOL:automatic]
synonym: "elastic connective tissue of trunk of aortic tree" EXACT [OBOL:automatic]
synonym: "elastic tissue of adult aorta" EXACT [OBOL:automatic]
synonym: "elastic tissue of aorta" EXACT [OBOL:automatic]
synonym: "elastic tissue of dorsal aorta" EXACT [OBOL:automatic]
synonym: "elastic tissue of trunk of aortic tree" EXACT [OBOL:automatic]
synonym: "textus connectivus elasticus of adult aorta" EXACT [OBOL:automatic]
synonym: "textus connectivus elasticus of aorta" EXACT [OBOL:automatic]
synonym: "textus connectivus elasticus of dorsal aorta" EXACT [OBOL:automatic]
synonym: "textus connectivus elasticus of trunk of aortic tree" EXACT [OBOL:automatic]
synonym: "trunk of aortic tree elastic connective tissue" EXACT [OBOL:automatic]
synonym: "trunk of aortic tree elastic tissue" EXACT [OBOL:automatic]
synonym: "trunk of aortic tree textus connectivus elasticus" EXACT [OBOL:automatic]
xref: MA:0002859
is_a: UBERON:0003614 ! blood vessel elastic tissue
intersection_of: UBERON:0002521 ! elastic tissue
intersection_of: part_of UBERON:0000947 ! aorta
relationship: part_of UBERON:0000947 ! aorta

[Term]
id: UBERON:0003610
name: heart elastic tissue
namespace: uberon
def: "The type of heart connective tissue found in the endocardial layer that consists mainly of elastic fibers." [MP:0009863]
subset: pheno_slim
synonym: "cardiac elastic tissue" EXACT [MP:0009863]
synonym: "elastic connective tissue of heart" EXACT [OBOL:automatic]
synonym: "elastic tissue of heart" EXACT [OBOL:automatic]
synonym: "heart elastic connective tissue" EXACT [OBOL:automatic]
synonym: "heart textus connectivus elasticus" EXACT [OBOL:automatic]
synonym: "textus connectivus elasticus of heart" EXACT [OBOL:automatic]
xref: MA:0002858
is_a: UBERON:0003613 ! cardiovascular system elastic tissue
is_a: UBERON:0003837 ! thoracic segment connective tissue
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0002521 ! elastic tissue
intersection_of: part_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart

[Term]
id: UBERON:0003611
name: respiratory system elastic tissue
namespace: uberon
def: "An elastic tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius elastic connective tissue" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius elastic tissue" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius textus connectivus elasticus" EXACT [OBOL:automatic]
synonym: "elastic connective tissue of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "elastic connective tissue of respiratory system" EXACT [OBOL:automatic]
synonym: "elastic tissue of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "elastic tissue of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory system elastic connective tissue" EXACT [OBOL:automatic]
synonym: "respiratory system textus connectivus elasticus" EXACT [OBOL:automatic]
synonym: "textus connectivus elasticus of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "textus connectivus elasticus of respiratory system" EXACT [OBOL:automatic]
xref: EMAPA:37579 {source="MA:th"}
xref: MA:0001820
is_a: UBERON:0002521 ! elastic tissue
is_a: UBERON:0003570 ! respiratory system connective tissue
intersection_of: UBERON:0002521 ! elastic tissue
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0004777 ! respiratory system submucosa

[Term]
id: UBERON:0003613
name: cardiovascular system elastic tissue
namespace: uberon
def: "An elastic tissue that is part of a circulatory system [Automatically generated definition]." [OBOL:automatic]
synonym: "cardiovascular system elastic connective tissue" EXACT [OBOL:automatic]
synonym: "cardiovascular system textus connectivus elasticus" EXACT [OBOL:automatic]
synonym: "circulatory system elastic connective tissue" EXACT [OBOL:automatic]
synonym: "circulatory system elastic tissue" EXACT [OBOL:automatic]
synonym: "circulatory system textus connectivus elasticus" EXACT [OBOL:automatic]
synonym: "elastic connective tissue of cardiovascular system" EXACT [OBOL:automatic]
synonym: "elastic connective tissue of circulatory system" EXACT [OBOL:automatic]
synonym: "elastic tissue of cardiovascular system" EXACT [OBOL:automatic]
synonym: "elastic tissue of circulatory system" EXACT [OBOL:automatic]
synonym: "textus connectivus elasticus of cardiovascular system" EXACT [OBOL:automatic]
synonym: "textus connectivus elasticus of circulatory system" EXACT [OBOL:automatic]
xref: MA:0002857
is_a: UBERON:0002521 ! elastic tissue
intersection_of: UBERON:0002521 ! elastic tissue
intersection_of: part_of UBERON:0001009 ! circulatory system
relationship: part_of UBERON:0004535 ! cardiovascular system

[Term]
id: UBERON:0003614
name: blood vessel elastic tissue
namespace: uberon
def: "Elastic tissue layer that lines a blood vessel layer." [http://orcid.org/0000-0002-6601-2165, https://sourceforge.net/p/obo/mammalian-phenotype-requests/2026/]
subset: pheno_slim
synonym: "blood vessel elastic connective tissue" EXACT [OBOL:automatic]
synonym: "blood vessel textus connectivus elasticus" EXACT [OBOL:automatic]
synonym: "elastic connective tissue of blood vessel" EXACT [OBOL:automatic]
synonym: "elastic lamina" BROAD [MP:0006083]
synonym: "elastic laminae" BROAD OMO:0003004 [MP:0006083]
synonym: "elastic tissue of blood vessel" EXACT [OBOL:automatic]
synonym: "textus connectivus elasticus of blood vessel" EXACT [OBOL:automatic]
synonym: "vascular elastic lamina" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "vascular elastic laminae" EXACT OMO:0003004 [http://orcid.org/0000-0002-6601-2165]
synonym: "vascular elastic tissue" EXACT [MP:0006083]
xref: EMAPA:36300
xref: MA:0002856
is_a: UBERON:0003613 ! cardiovascular system elastic tissue
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0002521 ! elastic tissue
intersection_of: part_of UBERON:0001981 ! blood vessel
relationship: part_of UBERON:0001981 ! blood vessel

[Term]
id: UBERON:0003615
name: lung elastic tissue
namespace: uberon
def: "Elastic tissue that is part of a lung [Automatically generated definition]." [OBOL:automatic]
synonym: "elastic connective tissue of lung" EXACT [OBOL:automatic]
synonym: "elastic tissue of lung" EXACT [OBOL:automatic]
synonym: "lung elastic connective tissue" EXACT [OBOL:automatic]
synonym: "lung textus connectivus elasticus" EXACT [OBOL:automatic]
synonym: "pulmonary elastic fiber" NARROW [http://orcid.org/0000-0002-6601-2165]
synonym: "textus connectivus elasticus of lung" EXACT [OBOL:automatic]
xref: MA:0002860
is_a: UBERON:0000114 ! lung connective tissue
is_a: UBERON:0003611 ! respiratory system elastic tissue
intersection_of: UBERON:0002521 ! elastic tissue
intersection_of: part_of UBERON:0002048 ! lung

[Term]
id: UBERON:0003618
name: aorta tunica media
namespace: uberon
def: "The middle layer of the aorta wall, containing the smooth muscle layer and elastic fibers." [MP:0009873]
subset: pheno_slim
synonym: "adult aorta tunica media" EXACT [OBOL:automatic]
synonym: "dorsal aorta tunica media" EXACT [OBOL:automatic]
synonym: "trunk of aortic tree tunica media" EXACT [OBOL:automatic]
synonym: "tunica media of adult aorta" EXACT [OBOL:automatic]
synonym: "tunica media of aorta" EXACT [OBOL:automatic]
synonym: "tunica media of dorsal aorta" EXACT [OBOL:automatic]
synonym: "tunica media of trunk of aortic tree" EXACT [OBOL:automatic]
xref: EMAPA:35138
xref: FMA:74433
xref: MA:0002903
xref: SCTID:48467007
is_a: UBERON:0002522 ! tunica media
intersection_of: UBERON:0002522 ! tunica media
intersection_of: part_of UBERON:0000947 ! aorta
relationship: contributes_to_morphology_of UBERON:0004663 ! aorta wall
relationship: part_of UBERON:0004663 ! aorta wall

[Term]
id: UBERON:0003619
name: aorta tunica intima
namespace: uberon
def: "The innermost layer of the aorta, containing the endothelium and an inner elastic membrane." [MP:0009872]
subset: pheno_slim
synonym: "adult aorta tunica intima" EXACT [OBOL:automatic]
synonym: "dorsal aorta tunica intima" EXACT [OBOL:automatic]
synonym: "trunk of aortic tree tunica intima" EXACT [OBOL:automatic]
synonym: "tunica intima of adult aorta" EXACT [OBOL:automatic]
synonym: "tunica intima of aorta" EXACT [OBOL:automatic]
synonym: "tunica intima of dorsal aorta" EXACT [OBOL:automatic]
synonym: "tunica intima of trunk of aortic tree" EXACT [OBOL:automatic]
xref: BTO:0005553
xref: EMAPA:35137
xref: FMA:74419
xref: MA:0002904
xref: SCTID:362031007
is_a: UBERON:0002523 ! tunica intima
is_a: UBERON:0004797 ! blood vessel layer
intersection_of: UBERON:0002523 ! tunica intima
intersection_of: part_of UBERON:0000947 ! aorta
relationship: contributes_to_morphology_of UBERON:0004663 ! aorta wall
relationship: part_of UBERON:0004663 ! aorta wall

[Term]
id: UBERON:0003643
name: respiratory system arterial blood vessel
namespace: uberon
def: "An arterial blood vessel that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:37565 {source="MA:th"}
xref: MA:0001800
is_a: UBERON:0003504 ! respiratory system blood vessel
is_a: UBERON:0003509 ! arterial blood vessel
intersection_of: UBERON:0003509 ! arterial blood vessel
intersection_of: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0003644
name: kidney arterial blood vessel
namespace: uberon
def: "An arterial blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "kidney arterial system" RELATED [EMAPA:31436]
xref: EMAPA:31436
xref: MA:0002578
is_a: UBERON:0003509 ! arterial blood vessel
is_a: UBERON:0003517 ! kidney blood vessel
intersection_of: UBERON:0003509 ! arterial blood vessel
intersection_of: part_of UBERON:0002113 ! kidney

[Term]
id: UBERON:0003665
name: post-anal tail muscle
namespace: uberon
def: "A muscle organ that attaches to a tail vertebra [Automatically generated definition]." [OBOL:automatic]
synonym: "caudal muscle" EXACT []
synonym: "muscle organ of post-vent region" EXACT [OBOL:automatic]
synonym: "muscle organ of tail" EXACT [OBOL:automatic]
synonym: "post-vent region muscle organ" EXACT [OBOL:automatic]
synonym: "tail muscle" EXACT [MA:0000699]
synonym: "tail muscle organ" EXACT [OBOL:automatic]
xref: AAO:0000081
xref: BTO:0001905
xref: EMAPA:37759 {source="MA:th"}
xref: MA:0000699
xref: SCTID:113230005
is_a: UBERON:0004518 ! muscle of vertebral column
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: attaches_to UBERON:0001095 ! caudal vertebra
relationship: attaches_to UBERON:0001095 ! caudal vertebra
relationship: overlaps UBERON:0007812 ! post-anal tail
property_value: UBPROP:0000012 "the BTO class may possibly refer to an invertebrate structure" xsd:string {external_ontology="BTO"}

[Term]
id: UBERON:0003684
name: abdominal cavity
namespace: uberon
def: "The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity)." [UBERON:cjm]
subset: efo_slim
synonym: "cavitas abdominis" RELATED OMO:0003011 [GAID:17, Wikipedia:Abdominal_cavity]
synonym: "cavity of abdominal compartment" EXACT [FMA:12266]
synonym: "cavity of compartment of abdomen" EXACT [FMA:12266]
synonym: "space of abdominal compartment" EXACT [FMA:12266]
xref: EFO:0000213
xref: EMAPA:36505
xref: FMA:12266
xref: GAID:17
xref: galen:AbdominalCavity
xref: MA:0003057
xref: MESH:D034841
xref: NCIT:C12664
xref: SCTID:361294009
xref: UMLS:C0230168 {source="ncithesaurus:Abdominal_Cavity"}
xref: Wikipedia:Abdominal_cavity
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000916 ! abdomen
intersection_of: part_of UBERON:0002323 ! coelemic cavity lumen
relationship: luminal_space_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0035819 ! abdominopelvic cavity
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI
property_value: UBPROP:0000012 "in FMA this contains the pelvic cavity, but this is inconsistent with the concept of abdominopelvic cavity" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0003687
name: foramen magnum
namespace: uberon
def: "In anatomy, in the occipital bone, the foramen magnum is one of the several oval or circular apertures in the base of the skull, through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the Spinal Accessory nerve, vertebral arteries, the anterior and posterior spinal arteries, the membrana tectoria and alar ligaments. [WP,unvetted]." [Wikipedia:Foramen_magnum]
comment: Design pattern notes: check whether this fits the foramen design pattern
subset: pheno_slim
subset: vertebrate_core
xref: AAO:0010826
xref: BTO:0006035 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: EMAPA:37868 {source="MA:th"}
xref: FMA:75306
xref: GAID:228
xref: MESH:D005539
xref: NCIT:C12495
xref: SCTID:244679008
xref: TAO:0002045
xref: UMLS:C0016519 {source="ncithesaurus:Foramen_Magnum"}
xref: Wikipedia:Foramen_magnum
xref: ZFA:0005387
is_a: UBERON:0013685 ! foramen of skull
intersection_of: UBERON:0013685 ! foramen of skull
intersection_of: conduit_for UBERON:0001896 ! medulla oblongata
relationship: conduit_for UBERON:0001896 ! medulla oblongata
relationship: located_in UBERON:0001676 ! occipital bone
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/39/Gray130.png" xsd:anyURI
property_value: UBPROP:0000001 "Foramen in the occipital region of neurocranium to allow passage of spinal cord.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002045", ontology="TAO", source="TAO:wd"}

[Term]
id: UBERON:0003694
name: atlanto-axial joint
namespace: uberon
def: "The Atlanto-axial joint is of a complicated nature, comprising no fewer than four distinct joints. There is a pivot articulation between the odontoid process of the axis and the ring formed by the anterior arch and the transverse ligament of the atlas." [Wikipedia:Atlanto-axial_joint]
subset: pheno_slim
synonym: "articulatio atlantoaxialis" RELATED [Wikipedia:Atlanto-axial_joint]
synonym: "articulatio atlantoepistrophica" RELATED [Wikipedia:Atlanto-axial_joint]
synonym: "atlanto axial joint" EXACT [GAID:250]
synonym: "atlantoaxial" RELATED [Wikipedia:Atlanto-axial_joint]
synonym: "atlantoaxial joint" EXACT [GAID:250]
synonym: "lateral atlanto-axial joint" RELATED [Wikipedia:Atlanto-axial_joint]
synonym: "median atlanto-axial joint" RELATED [Wikipedia:Atlanto-axial_joint]
xref: FMA:25524
xref: GAID:250
xref: MESH:D001268
xref: NCIT:C32157
xref: SCTID:361832004
xref: UMLS:C0004168 {source="ncithesaurus:Atlanto-axial_Joint"}
xref: Wikipedia:Atlanto-axial_joint
is_a: UBERON:0000982 ! skeletal joint
intersection_of: UBERON:0000982 ! skeletal joint
intersection_of: connects UBERON:0001092 ! vertebral bone 1
intersection_of: connects UBERON:0001093 ! vertebral bone 2
relationship: connects UBERON:0001092 ! vertebral bone 1
relationship: connects UBERON:0001093 ! vertebral bone 2
relationship: part_of UBERON:0011138 ! postcranial axial skeletal system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png" xsd:anyURI

[Term]
id: UBERON:0003697
name: abdominal wall
namespace: uberon
def: "The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles." [ncithesaurus:Abdominal_Wall]
subset: pheno_slim
synonym: "abdominal wall proper" RELATED [FMA:10429]
synonym: "layers of the abdominal wall" RELATED [Wikipedia:Abdominal_wall]
synonym: "paries abdominalis" EXACT [Wikipedia:Abdominal_wall]
synonym: "paries abdominalis" RELATED OMO:0003011 [Wikipedia:Abdominal_wall]
synonym: "wall of abdomen" EXACT [FMA:259054]
synonym: "wall of abdomen proper" EXACT [FMA:10429]
xref: EMAPA:37064 {source="MA:th"}
xref: FMA:10429
xref: FMA:259054
xref: GAID:26
xref: MESH:D034861
xref: NCIT:C77608
xref: SCTID:181613000
xref: UMLS:C0836916 {source="ncithesaurus:Abdominal_Wall"}
xref: Wikipedia:Abdominal_wall
is_a: UBERON:0000060 ! anatomical wall
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0000916 ! abdomen
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI

[Term]
id: UBERON:0003703
name: extrahepatic bile duct
namespace: uberon
def: "Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct." [MESH:A03.159.183.079]
subset: pheno_slim
subset: vertebrate_core
synonym: "bile duct extrahepatic part" RELATED [MA:0002659]
synonym: "extrahepatic biliary system" RELATED [GAID:281]
xref: FMA:14678
xref: GAID:281
xref: MA:0002659
xref: MESH:D017734
xref: NCIT:C32573
xref: SCTID:276158002
xref: UMLS:C0206187 {source="ncithesaurus:Extrahepatic_Bile_Duct"}
is_a: UBERON:0002394 ! bile duct
property_value: editor_note "includes all the cystic duct, all the common bile duct and the extrahapetic part of the hepatic duct" xsd:string
property_value: RO:0002171 UBERON:0002107

[Term]
id: UBERON:0003704
name: intrahepatic bile duct
namespace: uberon
def: "Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct." [MESH:A03.159.183.158]
subset: pheno_slim
subset: vertebrate_core
synonym: "bile duct intrahepatic part" EXACT [MA:0001630]
synonym: "intrahepatic biliary system" RELATED []
xref: FMA:15766
xref: GAID:287
xref: MA:0001630
xref: MESH:D001653
xref: NCIT:C12677
xref: SCTID:362193005
xref: TAO:0005169
xref: UMLS:C0005401 {source="ncithesaurus:Intrahepatic_Bile_Duct"}
xref: ZFA:0005169
is_a: UBERON:0002394 {source="FMA"} ! bile duct
intersection_of: UBERON:0002394 ! bile duct
intersection_of: part_of UBERON:0002107 ! liver
relationship: contributes_to_morphology_of UBERON:0002107 ! liver
relationship: part_of UBERON:0002107 {source="MA"} ! liver
property_value: editor_note "includes the hepatic duct of the caudate lobe, and the intra- and inter- lobar bile ducts" xsd:string
property_value: UBPROP:0000001 "Duct that collects bile from the bile ductules and connects to the extrahepatic bile duct.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005169", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0003711
name: brachiocephalic vein
namespace: uberon
def: "The left and right brachiocephalic veins in the upper chest are formed by the union of each corresponding internal jugular vein and subclavian vein. This is at the level of the sternoclavicular joint. These great vessels merge to form the superior vena cava. The brachiocephalic veins are the major veins returning blood to the superior vena cava." [Wikipedia:Brachiocephalic_vein]
subset: human_reference_atlas
synonym: "brachiocephalic venous tree" EXACT [FMA:4723]
synonym: "innomiate vein" RELATED [Wikipedia:Brachiocephalic_vein]
synonym: "innominate trunk" RELATED [Wikipedia:Brachiocephalic_vein]
synonym: "innominate vein" EXACT [FMA:4723]
synonym: "innominate vein" RELATED [GAID:529, Wikipedia:Brachiocephalic_vein]
synonym: "innominate veins" RELATED [Wikipedia:Brachiocephalic_vein]
synonym: "vena brachiocephalica" RELATED OMO:0003011 [Wikipedia:Brachiocephalic_vein]
synonym: "venae anonyma" RELATED OMO:0003011 [Wikipedia:Brachiocephalic_vein]
xref: EHDAA2:0000182
xref: EHDAA:9868
xref: FMA:4723
xref: GAID:529
xref: galen:BrachiocephalicVein
xref: MESH:D016121
xref: NCIT:C32816
xref: SCTID:181371003
xref: UMLS:C0006095 {source="ncithesaurus:Innominate_Vein"}
xref: Wikipedia:Brachiocephalic_vein
is_a: UBERON:0001638 ! vein
relationship: connected_to UBERON:0001585 ! anterior vena cava
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0007204 ! brachiocephalic vasculature
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/9e/Gray1174.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003713
name: splenic vein
namespace: uberon
def: "A vein arising from the splenic trabecular vein in the hilum of the spleen that drains into the portal vein." [ncithesaurus:Splenic_Vein]
subset: human_reference_atlas
synonym: "lienal vein" RELATED [MA:0002164, Wikipedia:Splenic_vein]
synonym: "vena lienalis" RELATED OMO:0003011 [Wikipedia:Splenic_vein]
synonym: "vena splenica" EXACT OMO:0003011 [FMA:14331, FMA:TA]
xref: EMAPA:37226 {source="MA:th"}
xref: FMA:14331
xref: GAID:541
xref: galen:SplenicVein
xref: MA:0002164
xref: MESH:D013162
xref: NCIT:C33608
xref: SCTID:278029005
xref: UMLS:C0038001 {source="ncithesaurus:Splenic_Vein"}
xref: Wikipedia:Splenic_vein
is_a: UBERON:0001638 ! vein
relationship: connected_to UBERON:0001639 ! hepatic portal vein
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/5b/Gray1189.png" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e4/Bilebladder.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003714
name: neural tissue
namespace: uberon
def: "Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature." [FMA:9642]
synonym: "nerve tissue" EXACT [FMA:9642]
synonym: "nervous tissue" EXACT [FMA:9642]
synonym: "portion of neural tissue" EXACT [FMA:9642]
xref: AAO:0000325
xref: AEO:0000123
xref: EHDAA2:0003123
xref: FMA:9642
xref: GAID:609
xref: MESH:D009417
xref: NCIT:C13052
xref: SCTID:91728009
xref: UMLS:C0027757 {source="ncithesaurus:Nervous_Tissue"}
is_a: UBERON:0000479 ! tissue
intersection_of: UBERON:0000479 ! tissue
intersection_of: has_part CL:0000125 ! glial cell
intersection_of: has_part CL:0000540 ! neuron
disjoint_from: UBERON:0004755 ! skeletal tissue
relationship: has_part CL:0000125 ! glial cell
relationship: has_part CL:0000540 ! neuron
relationship: part_of UBERON:0001016 ! nervous system
property_value: UBPROP:0000001 "One of the four types of tissue in traditional classifications. Cells forming the brain, spinal cord and peripheral nervous system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000325", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000012 "FMA definition includes vasculature" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0003715
name: splanchnic nerve
namespace: uberon
def: "The major nerves supplying sympathetic innervation to the abdomen, including the greater, lesser, and lowest (or smallest) splanchnic nerves that are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses and the lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia." [MP:0008318]
subset: pheno_slim
synonym: "splanchnic nerves" RELATED [BAMS:spn]
synonym: "visceral nerve" RELATED [Wikipedia:Splanchnic_nerves]
xref: BAMS:spn
xref: EMAPA:37959 {source="MA:th"}
xref: FMA:5883
xref: GAID:800
xref: MESH:D013153
xref: SCTID:264198001
xref: Wikipedia:Splanchnic_nerves
is_a: UBERON:0034729 ! sympathetic nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: innervates UBERON:0000916 ! abdomen
relationship: contributes_to_morphology_of UBERON:0000013 ! sympathetic nervous system
relationship: innervates UBERON:0000916 ! abdomen
property_value: UBPROP:0000010 "All carry sympathetic fibers except for the pelvic splanchnic nerves, which carry parasympathetic fibers" xsd:string

[Term]
id: UBERON:0003726
name: thoracic nerve
namespace: uberon
def: "The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls." [MESH:A08.800.800.720.800]
synonym: "nervi thoracici" RELATED OMO:0003011 [Wikipedia:Thoracic_nerves]
synonym: "nervus thoracis" EXACT OMO:0003011 [FMA:5860, FMA:TA]
synonym: "pectoral nerve" RELATED [GAID:857]
synonym: "thoracic spinal nerve" EXACT [FMA:5860]
xref: FMA:5860
xref: GAID:857
xref: MESH:D013900
xref: neuronames:1725
xref: SCTID:360498003
xref: Wikipedia:Thoracic_nerves
is_a: UBERON:0001780 ! spinal nerve
intersection_of: UBERON:0001780 ! spinal nerve
intersection_of: extends_fibers_into UBERON:0003038 ! thoracic spinal cord
relationship: extends_fibers_into UBERON:0003038 ! thoracic spinal cord

[Term]
id: UBERON:0003727
name: intercostal nerve
namespace: uberon
def: "The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]." [Wikipedia:Intercostal_nerves]
synonym: "anterior ramus of thoracic nerve" EXACT [FMA:6028]
synonym: "anterior ramus of thoracic spinal nerve" EXACT [FMA:6028]
synonym: "nervi intercostales" RELATED OMO:0003011 [Wikipedia:Intercostal_nerves]
synonym: "ramus anterior, nervus thoracicus" EXACT [FMA:6028]
synonym: "thoracic anterior ramus" EXACT [FMA:6028]
synonym: "ventral ramus of thoracic spinal nerve" EXACT [FMA:6028]
xref: EMAPA:18227
xref: FMA:6028
xref: GAID:858
xref: MESH:D007367
xref: NCIT:C32825
xref: SCTID:279568001
xref: UMLS:C1285089 {source="ncithesaurus:Intercostal_Nerve"}
xref: Wikipedia:Intercostal_nerves
is_a: UBERON:0001780 ! spinal nerve
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b1/Gray819.png" xsd:anyURI

[Term]
id: UBERON:0003728
name: mediastinum
namespace: uberon
def: "The central part of the thoracic cavity enclosed by the left and right pleurae." [UBERON:cjm, Wikipedia:Mediastinum]
subset: efo_slim
subset: pheno_slim
synonym: "mediastinal part of chest" EXACT [FMA:9826]
xref: CALOHA:TS-2338
xref: EFO:0003057
xref: EMAPA:36001
xref: FMA:9826
xref: GAID:94
xref: MA:0003075
xref: MESH:D008482
xref: NCIT:C12748
xref: SCTID:181217005
xref: UMLS:C0025066 {source="ncithesaurus:Mediastinum"}
xref: Wikipedia:Mediastinum
is_a: UBERON:0002553 ! anatomical cavity
relationship: part_of UBERON:0002224 ! thoracic cavity
relationship: surrounded_by UBERON:0035431 {source="FMA"} ! mediastinal pleura
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/ab/Mediastinum.png" xsd:anyURI
property_value: UBPROP:0000007 "mediastinal" xsd:string

[Term]
id: UBERON:0003729
name: mouth mucosa
namespace: uberon
def: "A mucous membrane that lines the mouth." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "buccal mucosa" RELATED [GAID:951]
synonym: "mouth mucosa" EXACT [FMA:59660]
synonym: "mouth mucous membrane" EXACT [OBOL:accepted]
synonym: "mouth organ mucosa" EXACT [OBOL:accepted]
synonym: "mucosa of mouth" EXACT [OBOL:accepted]
synonym: "mucosal lining of mouth" RELATED [MA:0002794]
synonym: "mucous membrane of mouth" EXACT [FMA:59660]
synonym: "oral mucosa" RELATED [GAID:951]
synonym: "oral mucous membrane" EXACT []
synonym: "oral part of viscerocranial mucosa" EXACT [FMA:59660]
synonym: "tunica mucosa oris" EXACT OMO:0003011 [FMA:59660, FMA:TA]
synonym: "tunica mucosa oris" RELATED OMO:0003011 [Wikipedia:Oral_mucosa]
xref: BTO:0002860
xref: CALOHA:TS-0716
xref: EMAPA:26937
xref: FMA:59660
xref: GAID:951
xref: MA:0002794
xref: MESH:D009061
xref: NCIT:C77637
xref: UMLS:C0026639 {source="ncithesaurus:Oral_Mucosa"}
xref: Wikipedia:Oral_mucosa
is_a: UBERON:0000344 ! mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000165 ! mouth
relationship: bounding_layer_of UBERON:0000165 ! mouth
relationship: continuous_with UBERON:0000355 ! pharyngeal mucosa
relationship: continuous_with UBERON:0001458 ! skin of lip
relationship: contributes_to_morphology_of UBERON:0001007 ! digestive system
relationship: part_of UBERON:0000165 ! mouth
property_value: curator_notes "this is defined as any mucous membrane of the mouth - including palate, lips, uvula, etc. ncit split mouth/oral mucosa into lip and buccal. In future we may split into masticatory/keratinized (gingiva + hard palate) vs lining/non-keratinized (lips, cheeks, floor of mouth, soft palate). FMA distinguishes between mucosa of mouth and region of mouth (the latter including the buccal mucosa)" xsd:string
property_value: UBPROP:0000001 "the mucous membrane epithelium of the mouth. It can be divided into three categories: masticatory, lining, and specialized[Wikipedia:Oral_mucosa]." xsd:string {source="Wikipedia:Oral_mucosa"}

[Term]
id: UBERON:0003824
name: nerve of thoracic segment
namespace: uberon
def: "A nerve that is part of a thorax [Automatically generated definition]." [OBOL:automatic]
synonym: "nerve of thorax" EXACT [OBOL:automatic]
synonym: "thoracic segment nerve" EXACT [MA:0000562]
synonym: "thorax nerve" EXACT [OBOL:automatic]
synonym: "upper body nerve" RELATED [MA:0000562]
xref: EMAPA:37265 {source="MA:th"}
xref: MA:0000562
xref: MESH:D013900
xref: SCTID:359876006
is_a: UBERON:0003439 ! nerve of trunk region
intersection_of: UBERON:0001021 ! nerve
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0000915 ! thoracic segment of trunk

[Term]
id: UBERON:0003825
name: nerve of abdominal segment
namespace: uberon
def: "A nerve that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic]
synonym: "abdominal segment nerve" EXACT [MA:0000528]
xref: EMAPA:37061 {source="MA:th"}
xref: MA:0000528
is_a: UBERON:0003439 ! nerve of trunk region
intersection_of: UBERON:0001021 ! nerve
intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk
relationship: part_of UBERON:0002417 ! abdominal segment of trunk

[Term]
id: UBERON:0003827
name: thoracic segment bone
namespace: uberon
def: "A bone that is part of a thorax [Automatically generated definition]." [OBOL:automatic]
synonym: "bone of thorax" EXACT [OBOL:automatic]
synonym: "bone organ of thorax" EXACT [OBOL:automatic]
synonym: "thorax bone" EXACT [OBOL:automatic]
synonym: "thorax bone organ" EXACT [OBOL:automatic]
synonym: "upper body bone" RELATED [MA:0000559]
xref: EMAPA:37247 {source="MA:th"}
xref: MA:0000559
xref: SCTID:426649006
is_a: UBERON:0003463 ! trunk bone
is_a: UBERON:0005181 ! thoracic segment organ
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk

[Term]
id: UBERON:0003828
name: abdominal segment bone
namespace: uberon
def: "A bone that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic]
synonym: "abdominal segment of trunk bone" EXACT [OBOL:automatic]
synonym: "abdominal segment of trunk bone organ" EXACT [OBOL:automatic]
synonym: "bone of abdominal segment of trunk" EXACT [OBOL:automatic]
synonym: "bone organ of abdominal segment of trunk" EXACT [OBOL:automatic]
xref: EMAPA:37058 {source="MA:th"}
xref: MA:0000525
is_a: UBERON:0003463 ! trunk bone
is_a: UBERON:0005173 ! abdominal segment element
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk

[Term]
id: UBERON:0003829
name: urethra muscle tissue
namespace: uberon
def: "Any muscle tissue that is part of the urethra." [UBERON:cjm]
synonym: "urethral muscle layer" RELATED [MA:0002649]
xref: EMAPA:37787 {source="MA:th"}
xref: MA:0002649
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005090 ! muscle structure
intersection_of: UBERON:0005090 ! muscle structure
intersection_of: part_of UBERON:0000057 ! urethra
relationship: part_of UBERON:0000057 ! urethra

[Term]
id: UBERON:0003830
name: thoracic segment muscle
namespace: uberon
def: "Any muscle organ that is part of a thorax [Automatically generated definition]." [OBOL:automatic]
synonym: "muscle organ of thorax" EXACT [OBOL:automatic]
synonym: "thorax muscle organ" EXACT [OBOL:automatic]
synonym: "upper body muscle" RELATED [MA:0000561]
xref: MA:0000561
is_a: UBERON:0001774 ! skeletal muscle of trunk
is_a: UBERON:0005181 ! thoracic segment organ
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0004464 {source="prolog"} ! musculature of thorax

[Term]
id: UBERON:0003831
name: respiratory system muscle
namespace: uberon
def: "Any muscle organ that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius muscle organ" EXACT [OBOL:automatic]
synonym: "muscle organ of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "muscle organ of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory system muscle organ" EXACT [OBOL:automatic]
xref: EMAPA:35733
xref: MA:0001828
is_a: UBERON:0001630 ! muscle organ
intersection_of: UBERON:0001630 ! muscle organ
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0003832
name: esophagus muscle
namespace: uberon
def: "Any muscle organ that is part of a esophagus [Automatically generated definition]." [OBOL:automatic]
synonym: "esophageal muscle" EXACT []
synonym: "esophagus muscle organ" EXACT [OBOL:automatic]
synonym: "gullet muscle organ" EXACT [OBOL:automatic]
synonym: "muscle organ of esophagus" EXACT [OBOL:automatic]
synonym: "muscle organ of gullet" EXACT [OBOL:automatic]
synonym: "muscle organ of oesophagus" EXACT [OBOL:automatic]
synonym: "oesophagus muscle organ" EXACT [OBOL:automatic]
xref: EMAPA:26983
xref: MA:0002682
xref: SCTID:360961009
is_a: UBERON:0001630 ! muscle organ
is_a: UBERON:0005181 ! thoracic segment organ
is_a: UBERON:0013765 ! digestive system element
intersection_of: UBERON:0001630 ! muscle organ
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001096 {source="MA"} ! wall of esophagus
property_value: editor_note "merge muscle and muscle layer?" xsd:string

[Term]
id: UBERON:0003833
name: abdominal segment muscle
namespace: uberon
def: "A muscle organ that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic]
synonym: "abdominal segment of trunk muscle organ" EXACT [OBOL:automatic]
synonym: "muscle organ of abdominal segment of trunk" EXACT [OBOL:automatic]
xref: EMAPA:37060 {source="MA:th"}
xref: MA:0000527
is_a: UBERON:0001774 ! skeletal muscle of trunk
is_a: UBERON:0005173 ! abdominal segment element
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk

[Term]
id: UBERON:0003834
name: thoracic segment blood vessel
namespace: uberon
def: "A blood vessel that is part of a thorax [Automatically generated definition]." [OBOL:automatic]
synonym: "blood vessel of thorax" EXACT [OBOL:automatic]
synonym: "thorax blood vessel" EXACT [OBOL:automatic]
synonym: "upper body blood vessel" RELATED [MA:0000558]
xref: EMAPA:37238 {source="MA:th"}
xref: MA:0000558
is_a: UBERON:0003513 ! trunk blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0000915 ! thoracic segment of trunk

[Term]
id: UBERON:0003835
name: abdominal segment blood vessel
namespace: uberon
def: "A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic]
synonym: "abdominal segment of trunk blood vessel" EXACT [OBOL:automatic]
synonym: "blood vessel of abdominal segment of trunk" EXACT [OBOL:automatic]
xref: EMAPA:37057 {source="MA:th"}
xref: MA:0000524
is_a: UBERON:0003513 ! trunk blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk
relationship: part_of UBERON:0002417 ! abdominal segment of trunk

[Term]
id: UBERON:0003836
name: abdominal segment skin
namespace: uberon
def: "A skin of body that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic]
synonym: "abdominal segment of trunk skin" EXACT [OBOL:automatic]
synonym: "skin of abdominal segment of trunk" EXACT [OBOL:automatic]
xref: EMAPA:37063 {source="MA:th"}
xref: FMA:264898
xref: MA:0000530
is_a: UBERON:0001085 ! skin of trunk
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk
relationship: part_of UBERON:0002417 ! abdominal segment of trunk

[Term]
id: UBERON:0003837
name: thoracic segment connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a thorax [Automatically generated definition]." [OBOL:automatic]
synonym: "connective tissue of thorax" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of thorax" EXACT [OBOL:automatic]
synonym: "textus connectivus of thorax" EXACT [OBOL:automatic]
synonym: "thorax connective tissue" EXACT [OBOL:automatic]
synonym: "thorax portion of connective tissue" EXACT [OBOL:automatic]
synonym: "thorax textus connectivus" EXACT [OBOL:automatic]
synonym: "upper body connective tissue" RELATED [MA:0000560]
xref: EMAPA:37253 {source="MA:th"}
xref: MA:0000560
is_a: UBERON:0003586 ! trunk connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0000915 ! thoracic segment of trunk

[Term]
id: UBERON:0003838
name: abdominal segment connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic]
synonym: "abdominal segment of trunk connective tissue" EXACT [OBOL:automatic]
synonym: "abdominal segment of trunk portion of connective tissue" EXACT [OBOL:automatic]
synonym: "abdominal segment of trunk textus connectivus" EXACT [OBOL:automatic]
synonym: "connective tissue of abdominal segment of trunk" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of abdominal segment of trunk" EXACT [OBOL:automatic]
synonym: "textus connectivus of abdominal segment of trunk" EXACT [OBOL:automatic]
xref: EMAPA:37059 {source="MA:th"}
xref: MA:0000526
is_a: UBERON:0003586 ! trunk connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk
relationship: part_of UBERON:0002417 ! abdominal segment of trunk

[Term]
id: UBERON:0003842
name: neural tube lumen
namespace: uberon
alt_id: UBERON:0005713
def: "An anatomical space that surrounded_by a neural tube." [OBOL:automatic]
synonym: "cavity of neural tube" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "central lumen" RELATED []
synonym: "lumen of neural tube" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "neural lumen" RELATED [EHDAA:2889]
synonym: "neural tube neural lumen" EXACT [EHDAA2:0001269]
synonym: "neurocoel" RELATED [VHOG:0001119]
synonym: "prosencoel" NARROW []
xref: AAO:0011073
xref: EHDAA2:0001269
xref: EHDAA:2889
xref: EHDAA:914
xref: EMAPA:16167
xref: VHOG:0001119
xref: XAO:0000252
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0001049 ! neural tube
relationship: luminal_space_of UBERON:0001049 ! neural tube
relationship: part_of UBERON:0001049 ! neural tube
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001119", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003848
name: gonadal vein
namespace: uberon
def: "In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted]." [Wikipedia:Gonadal_vein]
synonym: "gonad vein" EXACT [OBOL:automatic]
synonym: "gonada vein" EXACT [OBOL:automatic]
synonym: "vein of gonad" EXACT [OBOL:automatic]
synonym: "vein of gonada" EXACT [OBOL:automatic]
xref: EHDAA2:0000719
xref: EHDAA:8703
xref: SCTID:278192008
xref: VHOG:0001340
xref: Wikipedia:Gonadal_vein
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: attaches_to UBERON:0000991 ! gonad
relationship: attaches_to UBERON:0000991 ! gonad
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png" xsd:anyURI

[Term]
id: UBERON:0003849
name: mesencephalic neural crest
namespace: uberon
def: "A neural crest that has_potential_to_developmentally_contribute_to a midbrain." [OBOL:automatic]
subset: efo_slim
subset: vertebrate_core
synonym: "mesencephalic neural crest" EXACT [ZFA:0000935]
synonym: "neural crest midbrain" EXACT [ZFA:0000935]
xref: EFO:0003591
xref: EHDAA2:0001101
xref: EHDAA:360
xref: TAO:0000935
xref: VHOG:0000796
xref: ZFA:0000935
is_a: UBERON:0002342 ! neural crest
is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest
intersection_of: UBERON:0002342 ! neural crest
intersection_of: has_potential_to_developmentally_contribute_to UBERON:0001891 ! midbrain
relationship: has_potential_to_developmentally_contribute_to UBERON:0001891 ! midbrain
property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000796", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003852
name: rhombencephalon neural crest
namespace: uberon
def: "A neural crest that has_potential_to_developmentally_contribute_to a hindbrain." [OBOL:automatic]
subset: vertebrate_core
synonym: "neural crest hindbrain" EXACT [ZFA:0007063]
synonym: "rhombencephalic neural crest" EXACT [ZFA:0007063]
synonym: "rhombomere neural crest" RELATED [EMAPA:35747]
xref: EHDAA2:0001628
xref: EHDAA:362
xref: EMAPA:35747
xref: TAO:0007063
xref: VHOG:0001210
xref: ZFA:0007063
is_a: UBERON:0002342 ! neural crest
is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest
intersection_of: UBERON:0002342 ! neural crest
intersection_of: has_potential_to_developmentally_contribute_to UBERON:0002028 ! hindbrain
relationship: has_potential_to_developmentally_contribute_to UBERON:0002028 ! hindbrain
property_value: UBPROP:0000001 "Cranial neural crest that is part of the hindbrain.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0007063", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001210", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003853
name: spinal cord neural crest
namespace: uberon
def: "A neural crest that has_potential_to_developmentally_contribute_to a spinal cord." [OBOL:automatic]
synonym: "neural crest spinal cord" EXACT [VHOG:0001006]
synonym: "spinal neural crest" RELATED [VHOG:0001006]
xref: EHDAA:696
xref: EMAPA:16163
xref: EMAPA:16881
xref: VHOG:0001006
is_a: UBERON:0002342 ! neural crest
intersection_of: UBERON:0002342 ! neural crest
intersection_of: has_potential_to_developmentally_contribute_to UBERON:0002240 ! spinal cord
relationship: has_potential_to_developmentally_contribute_to UBERON:0002240 ! spinal cord
property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...)[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001006", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003854
name: spinal cord neural plate
namespace: uberon
def: "A neural plate that develops_from a future spinal cord." [OBOL:automatic]
synonym: "neural plate of spinal cord" EXACT [OBOL:automatic]
xref: FMA:312957
xref: TAO:0007021
xref: VHOG:0000439
xref: ZFA:0007021
is_a: UBERON:0003075 ! neural plate
intersection_of: UBERON:0003075 ! neural plate
intersection_of: develops_from UBERON:0006241 ! future spinal cord
relationship: develops_from UBERON:0006241 {source="ZFA"} ! future spinal cord
property_value: UBPROP:0000001 "Neural plate that is part of the spinal cord. [Bgee_curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000439", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...)[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000439", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003855
name: gonad mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a developing gonad [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "gonada mesenchyme" EXACT [OBOL:automatic]
synonym: "mesenchyme of gonad" EXACT [OBOL:automatic]
synonym: "mesenchyme of gonada" EXACT [OBOL:automatic]
xref: EHDAA:5012
xref: EMAPA:16858
xref: EMAPA:17385
xref: VHOG:0001090
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0000991 ! gonad
relationship: part_of UBERON:0000991 ! gonad

[Term]
id: UBERON:0003869
name: presumptive ganglion
namespace: uberon
def: "A presumptive structure that has the potential to develop into a ganglion." [OBOL:automatic]
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0000045 ! ganglion
relationship: has_potential_to_develop_into UBERON:0000045 ! ganglion

[Term]
id: UBERON:0003885
name: mesometrium
namespace: uberon
def: "A mesentery that is part of a uterus [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "mesentery of uterus" RELATED [FMA:19816, http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/peritoneum.html, MA:0002931]
xref: EMAPA:35562
xref: FMA:19816
xref: MA:0002931
xref: SCTID:250172001
xref: Wikipedia:Mesometrium
is_a: UBERON:0001297 ! serosa of uterus
is_a: UBERON:0002095 ! mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0000995 ! uterus
relationship: part_of UBERON:0012332 ! broad ligament of uterus
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003886
name: future coelemic cavity lumen
namespace: uberon
def: "An anatomical cavity that has the potential to develop into a coelemic cavity lumen." [OBOL:automatic]
subset: grouping_class
subset: non_informative
synonym: "body cavity precursor" RELATED []
synonym: "future coelomic cavity lumen" EXACT []
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: has_potential_to_develop_into UBERON:0002323 ! coelemic cavity lumen
relationship: existence_ends_during UBERON:0000111 ! organogenesis stage
relationship: existence_starts_during UBERON:0000109 ! gastrula stage
relationship: has_potential_to_develop_into UBERON:0002323 ! coelemic cavity lumen
relationship: part_of UBERON:0000926 ! mesoderm

[Term]
id: UBERON:0003887
name: intraembryonic coelom
namespace: uberon
def: "The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom." [MGI:anna, MP:0012187]
subset: pheno_slim
synonym: "somatic coelom" EXACT [Wikipedia:Intraembryonic_coelom]
xref: EHDAA:251
xref: EMAPA:16088
xref: NCIT:C34195
xref: UMLS:C1512940 {source="ncithesaurus:Intraembryonic_Coelom"}
xref: VHOG:0000316
xref: Wikipedia:Intraembryonic_coelom
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0003081 {source="Wikipedia"} ! lateral plate mesoderm
relationship: part_of UBERON:0011997 ! coelom
property_value: editor_note "consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults" xsd:string
property_value: UBPROP:0000003 "(...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000316", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.166", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003889
name: fallopian tube
namespace: uberon
def: "Initial section of the oviduct through which the ova pass from the ovary to the uterus." [http://orcid.org/0000-0002-6601-2165, MGI:smb, MP:0003574]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "fallopian tubes" RELATED []
synonym: "female paramesonephric duct" RELATED [EHDAA2:0000504]
synonym: "mammalian oviduct" EXACT [https://sourceforge.net/p/geneontology/ontology-requests/8397/]
synonym: "paramesonephric duct of female" RELATED [EMAPA:35660]
synonym: "salpinges" BROAD OMO:0003004 []
synonym: "salpinx" BROAD []
synonym: "tuba uterina" RELATED OMO:0003011 [Wikipedia:Fallopian_tube]
synonym: "uterine tube (sensu Mammalia)" EXACT []
xref: CALOHA:TS-0732
xref: EHDAA2:0000504
xref: EMAPA:18984
xref: EMAPA:35660
xref: EV:0100112
xref: FMA:18245
xref: GAID:365
xref: galen:FallopianTube
xref: MA:0000385
xref: MESH:D005187
xref: NCIT:C12403
xref: SCTID:181463001
xref: UMLS:C0015560 {source="ncithesaurus:Fallopian_Tube"}
xref: Wikipedia:Fallopian_tube
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0013515 ! subdivision of oviduct
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0013515 ! subdivision of oviduct
intersection_of: develops_from UBERON:0003890 ! Mullerian duct
intersection_of: part_of UBERON:0000993 ! oviduct
relationship: connects UBERON:0000995 ! uterus
relationship: connects UBERON:0003984 ! uterine tube infundibulum
relationship: develops_from UBERON:0003890 ! Mullerian duct
relationship: in_lateral_side_of UBERON:0003975 {source="FMA-abduced-lr"} ! internal female genitalia
relationship: only_in_taxon NCBITaxon:40674 ! Mammalia
relationship: part_of UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0003975 ! internal female genitalia
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "Homologous to appendix testis" xsd:string {source="Wikipedia:Talk:Fallopian_tube#Homology"}

[Term]
id: UBERON:0003890
name: Mullerian duct
namespace: uberon
alt_id: UBERON:0005318
def: "Paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin[WP]. develops either by lengthwise splitting of the archinephric duct (in chondrichthyans and some amphibians) or by a elongated invagination of the coelomic epithelium (other vertebrates) In males, the oviducts regress. The cranial end of the oviduct maintains an opening into the coelom (which primitively may have been the anteriormost coelomic funnels connecting the nephrocoel with the coelom). This opening is the ostium tubae[USM]." [GO:0061205, http://www.usm.maine.edu/bio/courses/bio205/bio205_26_sex.html, Wikipedia:Paramesonephric_duct]
subset: pheno_slim
synonym: "ductus paramesonephricus" EXACT []
synonym: "early paramesonephric duct" NARROW [EHDAA2:0004048]
synonym: "Muellerian duct" EXACT []
synonym: "Müllerian duct" EXACT []
synonym: "paramesonephric duct" EXACT [EMAPA:27665]
xref: AAO:0010141
xref: EHDAA2:0004048
xref: EMAPA:27665
xref: GAID:1309
xref: MESH:D009095
xref: NCIT:C13260
xref: RETIRED_EHDAA2:0001399
xref: SCTID:308802006
xref: UMLS:C0026732 {source="ncithesaurus:Mullerian_Duct"}
xref: VHOG:0001199
xref: Wikipedia:Paramesonephric_duct
xref: XAO:0000330
is_a: UBERON:0000025 ! tube
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0015212 ! lateral structure
relationship: develops_from UBERON:0003064 {source="Wikipedia"} ! intermediate mesoderm
relationship: in_lateral_side_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0000922 ! embryo
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png" xsd:anyURI
property_value: UBPROP:0000001 "Either of the paired embryonic ducts developing into the uterine tubes, uterus, and vagina in the female and becoming largely obliterated in the male. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001199", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/paramesonephric+duct"}
property_value: UBPROP:0000001 "Transient developmental organ which gives rise to oviducts in female (documented to persist in some male frogs).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010141", ontology="AAO", source="AAO:RED"}
property_value: UBPROP:0000003 "In females, the archinephric (mesonephric) ducts tend to function only within the urinary systems. The muellerian duct arises embryologically next to the archinephric (wolffian) duct. In males, the muellerian duct regresses if it appears at all, but in females, the muellerian ducts become the oviducts of the reproductive system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001199", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.559", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "Sertoli cells secrete anti-Mullerian hormone (AMH) inducing the demise of this duct" xsd:string

[Term]
id: UBERON:0003891
name: stroma
namespace: uberon
def: "Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "stromal connective tissue" RELATED []
xref: FMA:81494
xref: NCIT:C67387
xref: UMLS:C0927195 {source="ncithesaurus:Stroma_Connective_Tissue"}
is_a: UBERON:0000064 ! organ part
relationship: composed_primarily_of UBERON:0002384 ! connective tissue
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: UBPROP:0000007 "stromal" xsd:string

[Term]
id: UBERON:0003894
name: liver primordium
namespace: uberon
def: "A small endodermal thickening in the foregut adjacent to the transverse septum. Invaginates forming the hepatic diverticulum." [ISBN:3211492755]
subset: efo_slim
subset: pheno_slim
subset: vertebrate_core
synonym: "embryological hepatic plate" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "hepatic plate" RELATED [EHDAA2:0000744]
synonym: "liver bud" RELATED INCONSISTENT [XAO:0003266, ZFA:0000124]
synonym: "liver endoderm" RELATED [EFO:0002577]
synonym: "primordium of the liver" EXACT [ncithesaurus:Primordium_of_the_Liver]
xref: AAO:0011058
xref: BTO:0003391
xref: EFO:0002577
xref: EFO:0003428
xref: EHDAA2:0000744
xref: EHDAA:973
xref: EMAPA:16847
xref: NCIT:C34277
xref: TAO:0000124
xref: UMLS:C0734013 {source="ncithesaurus:Hepatic_Cord"}
xref: UMLS:C1514451 {source="ncithesaurus:Primordium_of_the_Liver"}
xref: XAO:0003266
xref: ZFA:0000124
is_a: UBERON:0000485 {source="EHDAA2"} ! simple columnar epithelium
is_a: UBERON:0001048 {source="XAO"} ! primordium
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0006598 ! presumptive structure
is_a: UBERON:0009497 ! epithelium of foregut-midgut junction
intersection_of: UBERON:0001048 ! primordium
intersection_of: has_potential_to_develop_into UBERON:0002107 ! liver
relationship: develops_from UBERON:0001041 {notes="ventral foregut endoderm", source="Zaret 1996"} ! foregut
relationship: has_potential_to_develop_into UBERON:0002107 ! liver
relationship: part_of UBERON:0009550 {source="EHDAA2"} ! endoderm of foregut-midgut junction
property_value: editor_note "consider adding further subdivisions of the endoderm, e.g. ventral foregut. Note we place two EFO classes here, it's not clear how they differ" xsd:string

[Term]
id: UBERON:0003897
name: axial muscle
namespace: uberon
def: "One of the skeletal muscles of the head and neck, spine, and ribs." [HP:0003327]
subset: pheno_slim
xref: EHDAA:5982
xref: EMAPA:18167
xref: MA:0003153
xref: RETIRED_EHDAA2:0000160
xref: TAO:0001954
is_a: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: attaches_to_part_of UBERON:0005944 ! axial skeleton plus cranial skeleton
intersection_of: part_of UBERON:0013701 ! main body axis
relationship: attaches_to_part_of UBERON:0005944 ! axial skeleton plus cranial skeleton
relationship: part_of UBERON:0013700 ! axial musculature

[Term]
id: UBERON:0003898
name: skeletal muscle tissue of trunk
namespace: uberon
def: "A portion of skeletal muscle tissue in the trunk." [http://orcid.org/0000-0002-6601-2165]
synonym: "skeletal muscle of torso" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of torso" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of trunk" EXACT [OBOL:automatic]
synonym: "torso skeletal muscle" EXACT [OBOL:automatic]
synonym: "torso skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "trunk skeletal muscle" EXACT [OBOL:automatic]
synonym: "trunk skeletal muscle tissue" EXACT [OBOL:automatic]
xref: SCTID:244848007
is_a: UBERON:0001134 ! skeletal muscle tissue
intersection_of: UBERON:0001134 ! skeletal muscle tissue
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0004479 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! musculature of trunk
relationship: part_of UBERON:0013700 ! axial musculature

[Term]
id: UBERON:0003902
name: retinal neural layer
namespace: uberon
def: "The part of the retina that contains neurons and photoreceptor cells[GO]." [GO:0003407]
subset: human_reference_atlas
subset: pheno_slim
subset: vertebrate_core
synonym: "neural layer of retina" EXACT [FMA:58628]
synonym: "neural retina" EXACT [XAO:0003216, ZFA:0000046]
synonym: "neural retinal epithelium" RELATED [MA:000027]
synonym: "neuroretina" EXACT [ZFA:0000046]
synonym: "stratum nervosum (retina)" EXACT [FMA:58628]
synonym: "stratum nervosum retinae" EXACT OMO:0003011 [FMA:58628, FMA:TA]
xref: AAO:0011095
xref: BTO:0000929
xref: CALOHA:TS-0685
xref: EHDAA2:0001253
xref: EHDAA:4763
xref: EMAPA:17171
xref: EMAPA:18590
xref: FMA:58628
xref: MA:0000277
xref: NCIT:C33166
xref: TAO:0000046
xref: UMLS:C1518263 {source="ncithesaurus:Neural_Retina"}
xref: VHOG:0000535
xref: XAO:0003216
xref: ZFA:0000046
is_a: UBERON:0001781 ! layer of retina
intersection_of: UBERON:0001781 ! layer of retina
intersection_of: immediate_transformation_of UBERON:0005425 ! presumptive neural retina
relationship: developmentally_induced_by UBERON:0005426 ! lens vesicle
relationship: develops_from UBERON:0005425 ! presumptive neural retina
relationship: has_part CL:0000210 ! photoreceptor cell
relationship: immediate_transformation_of UBERON:0005425 {source="Bgee:AN"} ! presumptive neural retina
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000535", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003909
name: sinusoid
namespace: uberon
def: "Small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP]." [Wikipedia:Sinusoid_(blood_vessel)]
subset: vertebrate_core
synonym: "endothelium of irregular blood filled space" RELATED []
synonym: "sinusoidal blood vessel" EXACT []
synonym: "sinusoidal blood vessel endothelium" EXACT [ZFA:0005261]
synonym: "sinusoidal capillary" RELATED [http://www.medilexicon.com/medicaldictionary.php?t=13986]
synonym: "sinusoidal endothelium" RELATED []
xref: FMA:63131
xref: SCTID:340163004
xref: TAO:0005261
xref: Wikipedia:Sinusoid_(blood_vessel)
xref: ZFA:0005261
is_a: UBERON:2005260 {source="Wikipedia", source="ZFA"} ! fenestrated capillary
property_value: UBPROP:0000001 "Fenestrated blood vessel endothelium with pores that are large enough for blood cells to pass. The basal lamina and gap junctions may be discontinuous.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005261", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000007 "sinusoidal" xsd:string
property_value: UBPROP:0000012 "some sources give discontinuous capillary as synonym but this may be a subtype - see FMA:63198 discontinuous sinusoid (undefined)." xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0003914
name: epithelial tube
namespace: uberon
def: "Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GO:0060562, PMID:12526790]
synonym: "epithelial or endothelial tube" EXACT []
xref: AEO:0000114
xref: EHDAA2:0003114
xref: FBbt:00007474 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0000025 ! tube
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: has_quality PATO:0002299 ! tubular
property_value: curator_notes "contrast with a multi-tissue tube, which has as parts both epithelium, connective tissue, possibly muscle layers" xsd:string

[Term]
id: UBERON:0003915
name: endothelial tube
namespace: uberon
def: "Any endothelium that has the quality of being cylindrical [Automatically generated definition]." [OBOL:automatic]
is_a: UBERON:0001986 ! endothelium
is_a: UBERON:0003914 ! epithelial tube
intersection_of: UBERON:0001986 ! endothelium
intersection_of: has_quality PATO:0002299 ! tubular

[Term]
id: UBERON:0003918
name: kidney mesenchyme
namespace: uberon
def: "Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney[GO]." [GO:0072074]
subset: pheno_slim
synonym: "mesenchyme of kidney" EXACT []
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: has_potential_to_develop_into UBERON:0002113 ! kidney
relationship: has_potential_to_develop_into UBERON:0002113 ! kidney
property_value: editor_note "check this" xsd:string

[Term]
id: UBERON:0003920
name: venous blood vessel
namespace: uberon
def: "A blood vessel that carries blood from the capillaries toward the heart." [http://www.thefreedictionary.com/venous+blood+vessel]
comment: Compare to: vein
subset: human_reference_atlas
synonym: "segment of venous tree organ" EXACT [FMA:86188]
synonym: "venous tree organ segment" EXACT [FMA:86188]
xref: EMAPA:35932
xref: FMA:86188
xref: MA:0000066
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0004582 ! venous system
relationship: part_of UBERON:0004582 ! venous system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003921
name: pancreas primordium
namespace: uberon
def: "Embryonic structure that develops into pancreatic bud." [Wikipedia:Pancreas#Embryological_development]
subset: efo_slim
subset: vertebrate_core
synonym: "pancreatic anlage" RELATED [ZFA:0000254]
synonym: "pancreatic endoderm" RELATED [EFO:0002579]
synonym: "pancreatic primordium" EXACT []
synonym: "primordial pancreas" RELATED [FMA:79792]
xref: EFO:0002579
xref: EFO:0003434
xref: EHDAA2:0001382
xref: EHDAA:2163
xref: EMAPA:17066
xref: FMA:79792
xref: TAO:0000254
xref: XAO:0001101
xref: ZFA:0000254
is_a: UBERON:0001048 ! primordium
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0001048 ! primordium
intersection_of: has_potential_to_develop_into UBERON:0001264 ! pancreas
relationship: develops_from UBERON:0000925 {source="Wikipedia"} ! endoderm
relationship: has_potential_to_develop_into UBERON:0001264 ! pancreas
relationship: part_of UBERON:0007026 ! presumptive gut
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI
property_value: UBPROP:0000012 "in EHDAA2 this has dorsal and ventral primordia as parts. the buds are part of the primordium, with the ducts developing from the buds; only parenchyma and ducts have contribution from buds" xsd:string {external_ontology="EHDAA2"}
property_value: UBPROP:0000013 "revisit after standardizing terms 'primordium', 'anlagen', 'bud'" xsd:string

[Term]
id: UBERON:0003922
name: pancreatic epithelial bud
namespace: uberon
def: "The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]." [PMID:16417468, Wikipedia:Pancreatic_bud]
subset: efo_slim
synonym: "pancreas epithelium" RELATED [EMAPA:35645]
synonym: "pancreatic anlage" RELATED []
synonym: "pancreatic bud" EXACT [ZFA:0001390]
synonym: "pancreatic buds" EXACT OMO:0003004 [TAO:0001390]
xref: EFO:0003470
xref: EMAPA:35645
xref: NCIT:C34242
xref: SCTID:360398004
xref: TAO:0001390
xref: UMLS:C1283285 {source="ncithesaurus:Pancreatic_Bud"}
xref: Wikipedia:Pancreatic_bud
xref: ZFA:0001390
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0005911 ! endo-epithelium
is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac
relationship: develops_from UBERON:0001041 {source="Wikipedia:Pancreas#Embryological_development"} ! foregut
relationship: develops_from UBERON:0001555 ! digestive tract
relationship: develops_from UBERON:0002114 {exception="zebrafish", source="Wikipedia:Pancreatic_bud"} ! duodenum
relationship: develops_from UBERON:0009497 {source="EHDAA2-inferred"} ! epithelium of foregut-midgut junction
relationship: part_of UBERON:0003921 {source="EHDAA2"} ! pancreas primordium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/49/Suckale08FBS_fig1_pancreas_development.jpeg" xsd:anyURI
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI

[Term]
id: UBERON:0003923
name: dorsal pancreatic bud
namespace: uberon
def: "Pancreatic bud that gives rise to the accessory pancreatic duct." [Wikipedia:Pancreatic_bud]
subset: efo_slim
subset: vertebrate_core
synonym: "dorsal pancreas anlage" RELATED []
synonym: "dorsal pancreatic anlage" RELATED []
synonym: "pancreas dorsal primordium duct bud" EXACT [EHDAA2:0001385]
synonym: "pancreas primordium dorsal bud" EXACT []
synonym: "posterior pancreatic anlage" RELATED []
synonym: "posterior pancreatic bud" RELATED []
synonym: "primary pancreatic bud" EXACT [XAO:0000467]
xref: AAO:0011031
xref: EFO:0003465
xref: EHDAA2:0001385
xref: EMAPA:17067
xref: SCTID:361435005
xref: TAO:0001370
xref: VHOG:0001428
xref: Wikipedia:Pancreatic_bud
xref: XAO:0000467
xref: ZFA:0001370
is_a: UBERON:0003922 ! pancreatic epithelial bud
relationship: developmentally_induced_by UBERON:0002328 {gci_relation="part_of", gci_filler="NCBITaxon:10088", source="PMID:16417468"} ! notochord
relationship: developmentally_induced_by UBERON:0005805 {gci_relation="part_of", gci_filler="NCBITaxon:10088", source="PMID:16417468"} ! dorsal aorta
relationship: develops_from UBERON:0001045 {source="XAO"} ! midgut
relationship: part_of UBERON:0010375 {source="EHDAA2"} ! pancreas dorsal primordium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI
property_value: UBPROP:0000001 "The pancreatic bud that gives rise to the accessory pancreatic duct.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011031", ontology="AAO", source="XAO:curator"}
property_value: UBPROP:0000003 "In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001428", ontology="VHOG", source="DOI:10.1016/S0012-1606(03)00308-7 Field HA, Dong PD, Beis D, Stainier DY, Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Developmental Biology (2003), DOI:10.2337/diabetes.49.2.225 Polak M, Bouchareb-Banaei L, Scharfmann R, Czernichow P, Early pattern of differentiation in the human pancreas. Diabetes (2000)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0003924
name: ventral pancreatic bud
namespace: uberon
def: "Pancreatic bud that gives rise to the major pancreatic duct." [Wikipedia:Pancreatic_bud]
subset: efo_slim
subset: vertebrate_core
synonym: "anterior pancreatic anlage" RELATED []
synonym: "anterior pancreatic bud" RELATED []
synonym: "pancreas primordium ventral bud" EXACT []
synonym: "pancreas ventral primordium duct bud" EXACT [EHDAA2:0001389]
synonym: "ventral pancreas anlage" RELATED []
synonym: "ventral pancreatic anlage" RELATED []
xref: AAO:0011111
xref: EFO:0003464
xref: EHDAA2:0001389
xref: EMAPA:17256
xref: SCTID:361437002
xref: TAO:0001369
xref: VHOG:0001429
xref: Wikipedia:Pancreatic_bud
xref: XAO:0001103
xref: ZFA:0001369
is_a: UBERON:0003922 ! pancreatic epithelial bud
relationship: develops_from UBERON:0008835 {source="PMID:16417468", source="WP"} ! hepatic diverticulum
relationship: part_of UBERON:0010376 {source="EHDAA2"} ! pancreas ventral primordium
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI
property_value: UBPROP:0000003 "In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001429", ontology="VHOG", source="DOI:10.1016/S0012-1606(03)00308-7 Field HA, Dong PD, Beis D, Stainier DY, Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Developmental Biology (2003), DOI:10.2337/diabetes.49.2.225 Polak M, Bouchareb-Banaei L, Scharfmann R, Czernichow P, Early pattern of differentiation in the human pancreas. Diabetes (2000)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "the ventral pancreas and liver are derived from a common precursor cell population[PMID:16417468]. TODO - add this relationship." xsd:string
property_value: UBPROP:0000011 "The ventral pancreatic bud becomes the head and uncinate process, and comes from the hepatic diverticulum[WP]" xsd:string

[Term]
id: UBERON:0003928
name: digestive system duct
namespace: uberon
def: "A duct that is part of a digestive system [Automatically generated definition]." [OBOL:automatic]
synonym: "duct of digestive system" EXACT [OBOL:automatic]
synonym: "duct of gastrointestinal system" EXACT [OBOL:automatic]
synonym: "gastrointestinal system duct" EXACT [OBOL:automatic]
xref: TAO:0005162
xref: ZFA:0005162
is_a: UBERON:0000058 ! duct
intersection_of: UBERON:0000058 ! duct
intersection_of: part_of UBERON:0001007 ! digestive system
relationship: part_of UBERON:0001007 ! digestive system

[Term]
id: UBERON:0003929
name: digestive tract epithelium
namespace: uberon
def: "An epithelium that lines the lumen of the digestive tract." [http://orcid.org/0000-0002-6601-2165]
synonym: "alimentary tract epithelium" RELATED [OBOL:automatic]
synonym: "digestive tract epithelial tissue" EXACT [OBOL:automatic]
synonym: "epithelial tissue of digestive tract" EXACT [OBOL:automatic]
synonym: "epithelial tissue of gut" EXACT [OBOL:automatic]
synonym: "epithelium of digestive tract" EXACT [OBOL:automatic]
synonym: "epithelium of gut" EXACT [OBOL:automatic]
synonym: "gastrodermis" EXACT SENSU [https://orcid.org/0000-0003-3308-6245, NCBITaxon:6073]
synonym: "gut epithelial tissue" EXACT [OBOL:automatic]
synonym: "gut epithelium" EXACT [EHDAA2:0004567, MA:0003201, ZFA:0005123]
xref: BTO:0000956
xref: EHDAA2:0004567
xref: EMAPA:32928
xref: FBbt:00047166 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: MA:0003201
xref: NCIT:C12963
xref: TAO:0005123
xref: UMLS:C0836205 {source="ncithesaurus:Gut_Epithelium"}
xref: XAO:0003200
xref: ZFA:0005123
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001555 ! digestive tract
relationship: part_of UBERON:0001555 ! digestive tract
property_value: UBPROP:0000001 "Epithelium lining the lumen of the gut.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005123", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000008 "" xsd:string

[Term]
id: UBERON:0003932
name: cartilage element of chondrocranium
namespace: uberon
def: "A cartilage element of chondrocranium. Example: neurocranial trabecula." [https://orcid.org/0000-0002-6601-2165]
subset: efo_slim
synonym: "cartilage of chondrocranium" EXACT [OBOL:accepted]
synonym: "cartilaginous element of chondrocranium" EXACT [OBOL:accepted]
synonym: "chondrocranium cartilage" EXACT [ZFA:0001461]
synonym: "neurocranium cartilage" EXACT [ZFA:0001461]
xref: EFO:0003690
xref: TAO:0001461
xref: ZFA:0001461
is_a: UBERON:0003933 ! cranial cartilage
intersection_of: UBERON:0007844 ! cartilage element
intersection_of: part_of UBERON:0002241 ! chondrocranium
relationship: part_of UBERON:0002241 ! chondrocranium

[Term]
id: UBERON:0003933
name: cranial cartilage
namespace: uberon
def: "A cartilage element that is part of the cranial skeleton." [https://orcid.org/0000-0002-6601-2165, ZFA:0001458]
synonym: "cartilage of cranium" EXACT [OBOL:automatic]
synonym: "cranial cartilages" RELATED OMO:0003004 [ZFA:0001458]
synonym: "cranium cartilage" EXACT [OBOL:automatic]
xref: TAO:0001458
xref: ZFA:0001458
is_a: UBERON:0007844 ! cartilage element
intersection_of: UBERON:0007844 ! cartilage element
intersection_of: part_of UBERON:0010323 ! cranial skeletal system
relationship: part_of UBERON:0010323 ! cranial skeletal system
property_value: UBPROP:0000001 "Cartilage which is part of the cranium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001458", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0003937
name: reproductive gland
namespace: uberon
def: "Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction." [MP:0000653]
subset: organ_slim
subset: pheno_slim
synonym: "genitalia gland" EXACT [OBOL:automatic]
synonym: "gland of genitalia" EXACT [MP:0000653]
synonym: "gland of reproductive system" EXACT [OBOL:automatic]
synonym: "reproductive gland" EXACT [MA:0001751]
synonym: "reproductive system gland" EXACT [OBOL:automatic]
synonym: "sex gland" EXACT [MP:0000653]
xref: BTO:0006162 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: MA:0001751
is_a: UBERON:0002530 ! gland
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0000990 ! reproductive system

[Term]
id: UBERON:0003942
name: somatosensory system
namespace: uberon
alt_id: UBERON:0014511
def: "The sensory system for the sense of touch and pain." [NLXANAT:090818]
subset: pheno_slim
synonym: "somatic sensory system" EXACT []
synonym: "system for detection of somatic senses" EXACT []
xref: EMAPA:37954 {source="MA:th"}
xref: neuronames:2887
xref: NLXANAT:090818
xref: Wikipedia:Somatosensory_system
is_a: UBERON:0001032 ! sensory system
relationship: capable_of_part_of GO:0019233 ! sensory perception of pain
relationship: capable_of_part_of GO:0050975 ! sensory perception of touch
property_value: UBPROP:0000001 "The neural tissue involved in the transmission of sensory signals" xsd:string {source="MP:0000959"}
property_value: UBPROP:0000012 "MP defines this in a may more appropriate to somatosensory cortex" xsd:string {external_ontology="MP"}

[Term]
id: UBERON:0003946
name: placenta labyrinth
namespace: uberon
def: "The placental layers where embryonic blood vessels are surrounded by trophoblast cells and maternal blood." [MP:0001716]
subset: pheno_slim
synonym: "labyrinthine layer" EXACT [GO:0060713]
synonym: "labyrinthine layer of placenta" EXACT [GO:0060713]
synonym: "placental labyrinth" EXACT []
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
relationship: contributes_to_morphology_of UBERON:0001987 ! placenta
relationship: part_of UBERON:0001987 ! placenta
property_value: RO:0002161 NCBITaxon:9606 {source="http://placentation.ucsd.edu"}
property_value: seeAlso "http://placentation.ucsd.edu/placenta.html" xsd:anyURI
property_value: UBPROP:0000008 "Mouse-human differences: The mouse and human placentas have labyrinthine and villous types of interdigitation between maternal and fetal tissues, respectively ... The mouse placental labyrinth is composed of an intricate network of maternal blood spaces and embryonal blood vessels. Maternal and embryonal blood is separated by a placental barrier that consists of four cellular layers: layer I trophoblasts line the maternal lacunae, trophoblasts in layers II and III form syncytial-like layers, and endothelial cells line the embryonic vessels[DOI: 10.1073/pnas.96.14.8138 ]" xsd:string

[Term]
id: UBERON:0003952
name: anterior stroma of cornea
namespace: uberon
def: "The anterior segment of the lamellated connective tissue layer of the cornea." [MP:0003093]
subset: human_reference_atlas
subset: pheno_slim
synonym: "anterior stroma" BROAD [MP:0003093]
synonym: "cornea anterior stroma" EXACT [MP:0003093]
xref: EMAPA:37414 {source="MA:th"}
is_a: UBERON:0003566 ! head connective tissue
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: in_anterior_side_of UBERON:0001777 ! substantia propria of cornea
disjoint_from: UBERON:0003953 {source="lexical"} ! posterior stroma of cornea
relationship: contributes_to_morphology_of UBERON:0001777 ! substantia propria of cornea
relationship: in_anterior_side_of UBERON:0001777 ! substantia propria of cornea
relationship: part_of UBERON:0001777 ! substantia propria of cornea
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003953
name: posterior stroma of cornea
namespace: uberon
def: "The posterior segment of the lamellated connective tissue layer of the cornea." [MP:0003094]
subset: pheno_slim
synonym: "cornea posterior stroma" EXACT [MP:0003094]
synonym: "posterior stroma" BROAD [MP:0003094]
xref: EMAPA:37415 {source="MA:th"}
is_a: UBERON:0003566 ! head connective tissue
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: in_posterior_side_of UBERON:0001777 ! substantia propria of cornea
relationship: contributes_to_morphology_of UBERON:0001777 ! substantia propria of cornea
relationship: in_posterior_side_of UBERON:0001777 ! substantia propria of cornea
relationship: part_of UBERON:0001777 ! substantia propria of cornea

[Term]
id: UBERON:0003959
name: rete testis
namespace: uberon
def: "An anastomosing network of delicate tubules located in the hilum of the testicle (mediastinum testis) that carries sperm from the seminiferous tubules to the vasa efferentia[WP]." [MP:0006416, Wikipedia:Rete_testis]
subset: pheno_slim
synonym: "Haller's rete" EXACT [FMA:19834]
xref: EMAPA:18332
xref: FMA:19834
xref: GAID:399
xref: MA:0003013
xref: MESH:D012152
xref: NCIT:C33467
xref: SCTID:279617009
xref: UMLS:C0035278 {source="ncithesaurus:Rete_Testis"}
xref: Wikipedia:Rete_testis
is_a: UBERON:0004111 ! anatomical conduit
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
relationship: channel_for CL:0000019 ! sperm
relationship: channels_from UBERON:0001343 ! seminiferous tubule of testis
relationship: channels_into UBERON:0006946 ! efferent duct
relationship: develops_from UBERON:0005297 {source="Wikipedia"} ! testis sex cord
relationship: part_of UBERON:0005051 ! mediastinum testis
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg" xsd:anyURI
property_value: editor_note "add more specific classification e.g. anastomosing network - consider FMA:3726" xsd:string

[Term]
id: UBERON:0003967
name: cutaneous elastic tissue
namespace: uberon
def: "The slender connective tissue fiber in the extracellular matrix of skin tissue that is composed of microfibrils and amorphous elastin and is characterized by great elasticity." [MP:0008418]
subset: pheno_slim
synonym: "cutaneous elastic fiber" NARROW [MP:0008418]
synonym: "dermal elastic fiber" NARROW [MP:0008418]
xref: EMAPA:37841 {source="MA:th"}
is_a: UBERON:0002521 ! elastic tissue
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0002521 ! elastic tissue
intersection_of: part_of UBERON:0000014 ! zone of skin
relationship: contributes_to_morphology_of UBERON:0000014 ! zone of skin
relationship: part_of UBERON:0000014 ! zone of skin

[Term]
id: UBERON:0003970
name: placental labyrinth vasculature
namespace: uberon
def: "Blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate." [MP:0008803]
subset: pheno_slim
synonym: "placental labyrinth vascular network" EXACT []
synonym: "placental vasculature" RELATED [OBOL:automatic]
synonym: "vasculature of placenta labyrinth" EXACT []
is_a: UBERON:0006876 ! vasculature of organ
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0003946 ! placenta labyrinth
relationship: part_of UBERON:0003946 ! placenta labyrinth

[Term]
id: UBERON:0003975
name: internal female genitalia
namespace: uberon
def: "The internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina." [MP:0009209]
comment: TODO: Relabel. Make distinct organ class. See https://github.com/obophenotype/uberon/issues/547
subset: human_reference_atlas
subset: organ_slim
subset: pheno_slim
synonym: "female internal genitalia" EXACT [FMA:45654]
synonym: "internal female genital organ" EXACT [BTO:0003099]
synonym: "internal genitalia of female reproductive system" EXACT [OBOL:automatic]
synonym: "organa genitalia feminina interna" RELATED [BTO:0003099]
xref: BTO:0003099
xref: FMA:45654
xref: SCTID:303518005
is_a: UBERON:0003134 ! female reproductive organ
is_a: UBERON:0004175 ! internal genitalia
intersection_of: UBERON:0004175 ! internal genitalia
intersection_of: part_of UBERON:0000474 ! female reproductive system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0003978
name: valve
namespace: uberon
subset: grouping_class
synonym: "anatomical valve" EXACT [FMA:67611]
xref: EHDAA2:0004046
xref: EHDAA:1892
xref: EHDAA:4406
xref: FMA:67611
xref: galen:Valve
is_a: UBERON:0000064 ! organ part
relationship: capable_of GO:0065008 ! regulation of biological quality
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb" xsd:anyURI
property_value: UBPROP:0000007 "valvular" xsd:string

[Term]
id: UBERON:0003983
name: conus arteriosus
namespace: uberon
def: "A conical pouch formed from the upper and left angle of the right ventricle in the chordate heart, from which the pulmonary artery arises[WP]. the anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminates in the pulmonary trunk[MP]." [MP:0009464, Wikipedia:Conus_arteriosus]
xref: AAO:0010250
xref: Wikipedia:Conus_arteriosus
is_a: UBERON:0004151 ! cardiac chamber
relationship: part_of UBERON:0002080 ! heart right ventricle
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/46/Gray492.png" xsd:anyURI
property_value: UBPROP:0000001 "Receives blood from the left atrium and becomes the median truncus arteriosus.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010250", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000008 "Kardong says absent in adult tetrapods, check AAO" xsd:string
property_value: UBPROP:0000013 "we use the term CA for the anterior chamber if it is composed of cardiac muscle, contractile, and contains conal valves internally" xsd:string {source="ISBN:0073040584"}

[Term]
id: UBERON:0003984
name: uterine tube infundibulum
namespace: uberon
def: "The funnel-like expansion of the abdominal extremity of the uterine tube[MP]." [MP:0009466, Wikipedia:Infundibulum_of_uterine_tube]
subset: human_reference_atlas
subset: pheno_slim
synonym: "infundibulum" BROAD INCONSISTENT []
synonym: "infundibulum of fallopian tube" NARROW [FMA:18307]
synonym: "infundibulum of oviduct" EXACT [FMA:18307]
synonym: "infundibulum of uterine tube" EXACT [FMA:18307]
synonym: "infundibulum tubae uterinae" RELATED OMO:0003011 [Wikipedia:Infundibulum_of_uterine_tube]
xref: EMAPA:29897
xref: FMA:18307
xref: SCTID:362262001
xref: Wikipedia:Infundibulum_of_uterine_tube
is_a: UBERON:0013515 {source="FMA"} ! subdivision of oviduct
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0003889 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! fallopian tube
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:8782
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The third part of the uterine tube is the infundibulum. It terminates with the ostium of Fallopian tube, surrounded by fimbriae, one of which is attached to the ovary[Wikipedia:Infundibulum_of_uterine_tube]." xsd:string {source="Wikipedia:Infundibulum_of_uterine_tube"}
property_value: UBPROP:0000008 "In mammals, the uterine tube infundibulum is part of the fallopian tube. In birds, where there is no fallopian tube, the uterine tube infundibulum is part of the oviduct." xsd:string {xref="https://orcid.org/0000-0002-2825-0621"}

[Term]
id: UBERON:0004015
name: embryonic-extraembryonic boundary
namespace: uberon
def: "The connection between the embryo proper and extraembryonic tissues." [MP:0003890]
subset: pheno_slim
is_a: UBERON:0000015 ! non-material anatomical boundary
intersection_of: UBERON:0000015 ! non-material anatomical boundary
intersection_of: adjacent_to UBERON:0000478 ! extraembryonic structure
intersection_of: adjacent_to UBERON:0002050 ! embryonic structure
relationship: adjacent_to UBERON:0000478 ! extraembryonic structure
relationship: adjacent_to UBERON:0002050 ! embryonic structure

[Term]
id: UBERON:0004016
name: dermatome
namespace: uberon
def: "A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells." [AEO:0001017, AEO:JB]
subset: pheno_slim
synonym: "cutis plate" EXACT [Wikipedia:Cutis_plate]
synonym: "dermatomal mesenchyme" EXACT [Wikipedia:Cutis_plate]
synonym: "epimere mesoderm" RELATED []
synonym: "mesenchyma dermatomiale" RELATED OMO:0003011 [Wikipedia:Dermatomal_mesenchyme]
xref: AAO:0011028
xref: AEO:0001017
xref: BTO:0006248 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: EHDAA2_RETIRED:0003428
xref: EHDAA:1719
xref: EHDAA:1725
xref: EHDAA:1731
xref: EHDAA:1737
xref: EMAPA:32838
xref: FMA:295656
xref: NCIT:C61572
xref: UMLS:C0180383 {source="ncithesaurus:Dermatome"}
xref: Wikipedia:Dermatome_(embryology)
xref: XAO:0000220
is_a: UBERON:0017650 {source="AEO"} ! developing mesenchymal structure
relationship: develops_from UBERON:0004290 {source="EHDAA2-abduced"} ! dermomyotome
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f3/Gray64.png" xsd:anyURI
property_value: UBPROP:0000013 "Not to be confused with 'dermatome segment of skin'." xsd:string

[Term]
id: UBERON:0004022
name: germinal neuroepithelium
namespace: uberon
def: "The single layer of epithelial cells that lines the early neural tube and develops into the nervous system and into the neural crest cells." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0004261]
subset: pheno_slim
synonym: "germinal neuroepithelial layer" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "germinal neuroepithelium" EXACT [NCBIBook:NBK10047]
synonym: "original neural tube" EXACT [NCBIBook:NBK10047]
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
is_a: UBERON:0034706 {source="NCBIBook:NBK10047"} ! proliferating neuroepithelium
disjoint_from: UBERON:0006934 ! sensory epithelium
relationship: adjacent_to UBERON:0003842 ! neural tube lumen
relationship: bounding_layer_of UBERON:0001049 ! neural tube
relationship: part_of UBERON:0001049 ! neural tube
property_value: UBPROP:0000011 "As the cells adjacent to the lumen continue to divide, the migrating cells form a second layer around the original neural tube. This layer becomes progressively thicker as more cells are added to it from the germinal neuroepithelium. This new layer is called the mantle (or intermediate) zone, and the germinal epithelium is now called the ventricular zone (and, later, the ependyma)[NCBIBook:NBK10047]" xsd:string

[Term]
id: UBERON:0004027
name: chorionic plate
namespace: uberon
def: "That portion of the chorionic wall in the region of its uterine attachment, which gives rise to chorionic villi; it consists of the mesoderm that lines the chorionic vesicle and, on the maternal side, of the trophoblast that lines the intervillous spaces; in the last half of gestation, the mesodermal connective tissue is largely replaced by fibrinoid material, and the amnionic membrane is adherent to the fetal side of the plate." [http://www.medilexicon.com/medicaldictionary.php?t=69523, MP:0004560]
subset: human_reference_atlas
subset: pheno_slim
xref: BTO:0002879
xref: EMAPA:31872
xref: NCIT:C34123
xref: SCTID:256391000
xref: UMLS:C0230972 {source="ncithesaurus:Chorionic_Plate"}
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0005292 ! extraembryonic tissue
relationship: contributes_to_morphology_of UBERON:0003124 ! chorion membrane
relationship: part_of UBERON:0003124 ! chorion membrane
relationship: part_of UBERON:8600038 ! placental disc
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004053
name: external male genitalia
namespace: uberon
def: "The external masculine genital organs, including the penis and scrotum." [MP:0009199]
comment: TODO: Relabel. Make distinct organ class. See https://github.com/obophenotype/uberon/issues/547
subset: organ_slim
subset: pheno_slim
synonym: "external male genital organ" EXACT [BTO:0003097]
synonym: "male external genitalia" EXACT [FMA:45642]
synonym: "organa genitalia masculina externa" RELATED [BTO:0003097]
xref: BTO:0003097
xref: EMAPA:30977
xref: FMA:45642
xref: galen:MaleExternalGenitalia
xref: SCTID:362264000
is_a: UBERON:0003135 ! male reproductive organ
is_a: UBERON:0004176 ! external genitalia
intersection_of: UBERON:0004176 ! external genitalia
intersection_of: part_of UBERON:0000079 ! male reproductive system
disjoint_from: UBERON:0005056 ! external female genitalia
disjoint_from: UBERON:0009196 ! indifferent external genitalia
relationship: contributes_to_morphology_of UBERON:0000079 ! male reproductive system

[Term]
id: UBERON:0004054
name: internal male genitalia
namespace: uberon
def: "The internal masculine genital organs, including the testes, epididymides, deferent ducts, seminal vesicles, prostate, ejaculatory ducts, and bulbourethral glands." [MP:0009205]
comment: TODO: Relabel. Make distinct organ class. See https://github.com/obophenotype/uberon/issues/547
subset: organ_slim
subset: pheno_slim
synonym: "internal male genital organ" EXACT [BTO:0003096]
synonym: "male internal genitalia" EXACT [FMA:45655]
synonym: "organa genitalia masculina interna" RELATED [BTO:0003096]
xref: BTO:0003096
xref: FMA:45655
xref: SCTID:310536002
is_a: UBERON:0003135 ! male reproductive organ
is_a: UBERON:0004175 ! internal genitalia
intersection_of: UBERON:0004175 ! internal genitalia
intersection_of: part_of UBERON:0000079 ! male reproductive system
relationship: contributes_to_morphology_of UBERON:0000079 ! male reproductive system
property_value: editor_note "consider splitting genitalia from genital organ" xsd:string

[Term]
id: UBERON:0004058
name: biliary ductule
namespace: uberon
def: "One of the fine terminal elements of the bile duct system, leaving the portal canal, and pursuing a course at the periphery of a lobule of the liver[BTO]. the excretory ducts of the liver that connect the interlobular ductules to the right or left hepatic duct[MP]." [BTO:0002840, MP:0009494]
subset: human_reference_atlas
subset: pheno_slim
synonym: "bile capillary" RELATED [BTO:0002840]
synonym: "bile ductule" EXACT [BTO:0002840]
synonym: "biliary ductule" EXACT [http://www.mondofacto.com/facts/dictionary?ductuli+biliferi]
synonym: "biliary ductule" RELATED [BTO:0002840]
synonym: "cholangiole" RELATED [BTO:0002840]
synonym: "ductuli biliferi" EXACT [http://www.mondofacto.com/facts/dictionary?ductuli+biliferi]
synonym: "terminal cholangiole" RELATED [http://orcid.org/0000-0002-6601-2165]
xref: BTO:0002840
xref: EMAPA:37440 {source="MA:th"}
xref: TAO:0005164
xref: ZFA:0005164
is_a: UBERON:0000025 ! tube
is_a: UBERON:0004119 ! endoderm-derived structure
relationship: adjacent_to UBERON:0001175 ! common hepatic duct
relationship: part_of UBERON:0002107 ! liver
relationship: part_of UBERON:0002394 {source="BTO"} ! bile duct
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "In ZFA, Digestive system duct that collects bile from the canaliculus and transports bile through the liver -- (check if the same) // The smallest and the most peripheral branches of the biliary tree consist of a portal part (portal ductule) and an intralobular part (intralobular ductule)" xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0004060
name: neural tube ventricular layer
namespace: uberon
def: "The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009689]
subset: pheno_slim
synonym: "ependymal layer" BROAD [NCBIBook:NBK10047]
synonym: "neural tube ependymal layer" EXACT [NCBIBook:NBK10047]
synonym: "neural tube ependymal zone" NARROW [MP:0009689]
synonym: "neural tube ventricular germinal zone" EXACT [NCBIBook:NBK10047]
synonym: "neural tube ventricular zone" EXACT [MP:0009689]
xref: EMAPA:17152
xref: EMAPA:35362
xref: EMAPA_RETIRED:16783
xref: MA:0003193
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
is_a: UBERON:0034706 {source="NCBIBook:NBK10047"} ! proliferating neuroepithelium
relationship: adjacent_to UBERON:0003842 ! neural tube lumen
relationship: develops_from UBERON:0004022 ! germinal neuroepithelium
relationship: immediate_transformation_of UBERON:0004022 {source="NCBIBook:NBK10047"} ! germinal neuroepithelium
relationship: part_of UBERON:0001049 ! neural tube
property_value: editor_note "consider merging with 'ventricular zone'; note that the MA class probably does not belong here, as this is an embryonic structure" xsd:string
property_value: UBPROP:0000001 "The layer of undifferentiated, proliferating cells that line the neural tube lumen" xsd:string {source="MP:0009689"}

[Term]
id: UBERON:0004061
name: neural tube mantle layer
namespace: uberon
def: "The layer of glia and differentiating neurons that forms as a second layer around the germinal neuroepithium; as this develops it comes to lie between the ventricular and marginal layers and includes the basal and alar plates. Develops into neurons and glia forming a gray matter layer." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009690]
subset: pheno_slim
synonym: "future brain marginal layer" RELATED [EMAPA:35360]
synonym: "neural tube intermediate zone" EXACT [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009690]
xref: EMAPA:17148
xref: EMAPA:35360
xref: neuronames:1367
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
is_a: UBERON:0034707 {source="NCBIBook:NBK10047"} ! differentiating neuroepithelium
relationship: adjacent_to UBERON:0004060 ! neural tube ventricular layer
relationship: adjacent_to UBERON:0004062 ! neural tube marginal layer
relationship: develops_from UBERON:0004022 {notes="by division", source="NCBIBook:NBK10047"} ! germinal neuroepithelium
relationship: part_of UBERON:0001049 ! neural tube

[Term]
id: UBERON:0004062
name: neural tube marginal layer
namespace: uberon
def: "The outermost layer of the neural tube that consists of axons from the developing mantle layer and will form the white matter." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009691]
subset: pheno_slim
synonym: "brain marginal zone" RELATED []
synonym: "neural tube marginal zone" EXACT [MP:0009691]
xref: EMAPA:17151
xref: neuronames:1368
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005162 ! multi cell part structure
relationship: adjacent_to UBERON:0004061 ! neural tube mantle layer
relationship: develops_from UBERON:0004061 {notes="forms from axons"} ! neural tube mantle layer
relationship: part_of UBERON:0001049 ! neural tube

[Term]
id: UBERON:0004064
name: neural tube basal plate
namespace: uberon
def: "The region of the mantle layer of the neural tube that lies ventral to the sulcus limitans and contains primarily motor neurons and interneurons." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009693, Wikipedia:Basal_plate_(neural_tube)]
subset: efo_slim
subset: pheno_slim
synonym: "basal plate" EXACT []
synonym: "basal plate of neural tube" EXACT [Wikipedia:Basal_plate_(neural_tube)]
synonym: "motor part of neural tube" RELATED []
synonym: "spinal cord basal plate" NARROW [MP:0009693]
synonym: "ventral part of neural tube" RELATED []
xref: AAO:0010561
xref: EFO:0001904
xref: NCIT:C34111
xref: neuronames:1372
xref: UMLS:C1511061 {source="ncithesaurus:Basal_Plate"}
xref: Wikipedia:Basal_plate_(neural_tube)
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
relationship: contributes_to_morphology_of UBERON:0004061 ! neural tube mantle layer
relationship: developmentally_induced_by UBERON:0002328 {gene="Shh", source="Swenson"} ! notochord
relationship: has_part CL:0000100 ! motor neuron
relationship: part_of UBERON:0004061 ! neural tube mantle layer
relationship: ventral_to UBERON:0005478 ! sulcus limitans of neural tube

[Term]
id: UBERON:0004066
name: frontonasal prominence
namespace: uberon
alt_id: UBERON:0006237
def: "The unpaired embryonic prominence that is formed by the tissues surrounding the forebrain vesicle and develops into the forehead and bridge of the nose/snout." [MP:0009901]
subset: pheno_slim
synonym: "embryonic frontonasal prominence" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "forebrain prominence" RELATED [MP:0009901]
synonym: "frontonasal mass" RELATED [MP:0009901]
synonym: "frontonasal process" RELATED [MP:0009901]
synonym: "prominentia frontonasalis" RELATED OMO:0003011 [Wikipedia:Frontonasal_prominence]
xref: EHDAA2:0000578
xref: EHDAA:4778
xref: EMAPA:16681
xref: FMA:293101
xref: NCIT:C34182
xref: SCTID:361486000
xref: UMLS:C1517321 {source="ncithesaurus:Frontonasal_Prominence"}
xref: VHOG:0001319
xref: Wikipedia:Frontonasal_prominence
is_a: UBERON:0009292 ! embryonic nasal process
relationship: intersects_midsagittal_plane_of UBERON:0000033 ! head
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/98/Gray44.png" xsd:anyURI

[Term]
id: UBERON:0004068
name: medial nasal prominence
namespace: uberon
def: "The central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it." [MP:0009903, Wikipedia:Medial_nasal_prominence]
subset: pheno_slim
synonym: "medial nasal process" EXACT [EHDAA2:0001076]
synonym: "medial nasal swelling" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "medial-nasal process" EXACT [EMAPA:16808]
synonym: "nasomedial prominence" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "prominentia nasalis medialis" EXACT OMO:0003011 [Wikipedia:Medial_nasal_prominence]
xref: EHDAA2:0001076
xref: EHDAA:4792
xref: EMAPA:16808
xref: FMA:295858
xref: SCTID:308877001
xref: VHOG:0000804
xref: Wikipedia:Medial_nasal_prominence
is_a: UBERON:0009292 ! embryonic nasal process
relationship: develops_from UBERON:0004066 {source="Wikipedia"} ! frontonasal prominence
relationship: in_lateral_side_of UBERON:0008816 ! embryonic head
relationship: part_of UBERON:0004066 {source="EHDAA2"} ! frontonasal prominence
relationship: part_of UBERON:0008816 ! embryonic head
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/85/Gray45.png" xsd:anyURI
property_value: UBPROP:0000011 "Fusion of right and left medial nasal processes forms a primary palate rostrally and the nasal septum caudally. The incisive bone, including upper incisor teeth and the rostral up- per lip, are derived from the primary palate. The nasal septum consists of bone, cartilage, and a patch of soft tissue membrane that separates right & left halves of the nasal cavity." xsd:string

[Term]
id: UBERON:0004087
name: vena cava
namespace: uberon
def: "Any of the veins that carries deoxygenated blood from a part of the body into the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Venae_cavae]
subset: pheno_slim
synonym: "caval vein" RELATED []
synonym: "venae cavae" RELATED OMO:0003004 [Wikipedia:Venae_cavae]
xref: AAO:0010215
xref: BTO:0001438
xref: EMAPA:18415
xref: FMA:321896
xref: GAID:547
xref: MA:0000068
xref: MESH:D014684
xref: NCIT:C12817
xref: SCTID:244405007
xref: UMLS:C0042460 {source="ncithesaurus:Vena_Cava"}
xref: Wikipedia:Venae_cavae
is_a: UBERON:0003479 ! thoracic cavity vein
is_a: UBERON:0013768 ! great vessel of heart
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/35/Relations_of_the_aorta,_trachea,_esophagus_and_other_heart_structures.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/7c/Heart_numlabels.png" xsd:anyURI

[Term]
id: UBERON:0004088
name: orbital region
namespace: uberon
def: "The subdivision of the face that includes the eye (eyeball plus adnexa such as eyelids) and the orbit of the skull and associated parts of the face such as the eyebrows, if present." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "content of orbital part of eye" EXACT [FMA:260119]
synonym: "eye region" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "ocular and peri-ocular region" RELATED []
synonym: "ocular region" RELATED []
synonym: "orbital content" RELATED [FMA:260119]
synonym: "orbital part of eye" RELATED [FMA:72951]
synonym: "orbital part of face" EXACT [http://orcid.org/0000-0002-6601-2165]
xref: FMA:260119
is_a: UBERON:0001444 ! subdivision of head
relationship: part_of UBERON:0001456 ! face
property_value: editor_note "note the FMA class is more narrow though, and is more like eye + muscles + vasculature. The FMA also has FMA:72951 orbital part of eye" xsd:string
property_value: UBPROP:0000012 "in HP covers eyelid, eyebrow." xsd:string {external_ontology="HP:0000284"}

[Term]
id: UBERON:0004089
name: midface
namespace: uberon
def: "The middle of the face including the nose and its associated bony structures[MW]." [HP:0000309, http://www.merriam-webster.com/medical/midface]
subset: pheno_slim
synonym: "lower face" RELATED []
synonym: "midface/lower face" RELATED []
synonym: "snout" RELATED SENSU [MA:0001910]
xref: EMAPA:32806
xref: FMA:285406
xref: MA:0001910
is_a: UBERON:0001444 ! subdivision of head
relationship: contributes_to_morphology_of UBERON:0001456 ! face
relationship: only_in_taxon NCBITaxon:89593 ! Craniata <chordates>
relationship: part_of UBERON:0001456 ! face
property_value: editor_note "this class is currently a union of the snout (e.g. in mouse), the midface and the lower face. Note that in MA, snout includes the whole jaw and should thus be more alike the lower face than the midface, so its placement here is not strictly accurate. In future we might introduce specific classes for each of these, and include the full parthood relationships. if this is done, then care should be taken to preserve inferences such as an abnormality of the lower face being an abnormality of the midface." xsd:string
property_value: UBPROP:0000007 "midfacial" xsd:string

[Term]
id: UBERON:0004100
name: renal collecting system
namespace: uberon
def: "The collecting duct system of the kidney consists of a series of tubules and ducts that connect the nephrons to the ureter. It participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and antidiuretic hormone." [HP:0004742, Wikipedia:Collecting_duct_system]
subset: human_reference_atlas
subset: pheno_slim
synonym: "collecting duct system" EXACT [Wikipedia:Collecting_duct_system]
synonym: "kidney collecting duct system" EXACT [Wikipedia:Collecting_duct_system]
synonym: "tubulus renalis colligens" RELATED OMO:0003011 [Wikipedia:Collecting_duct_system]
xref: FMA:265239
xref: SCTID:279371005
xref: Wikipedia:Collecting_duct_system
is_a: UBERON:0000467 ! anatomical system
relationship: part_of UBERON:0002113 ! kidney
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004111
name: anatomical conduit
namespace: uberon
def: "Any tube, opening or passage that connects two distinct anatomical spaces." [http://orcid.org/0000-0002-6601-2165]
subset: common_anatomy
synonym: "foramen" NARROW [EHDAA2:0003080]
synonym: "foramina" NARROW OMO:0003004 [https://orcid.org/0000-0002-6601-2165]
synonym: "opening" RELATED []
synonym: "ostia" RELATED OMO:0003004 []
synonym: "ostium" RELATED []
xref: AEO:0000080
xref: EHDAA2:0003080
xref: FMA:242873
xref: SCTID:346902003
xref: Wikipedia:Foramen
is_a: UBERON:0010000 ! multicellular anatomical structure
intersection_of: UBERON:0010000 ! multicellular anatomical structure
intersection_of: conduit_for UBERON:0000061 ! anatomical structure
intersection_of: has_part UBERON:0013686 ! anatomical conduit space
relationship: conduit_for UBERON:0000061 ! anatomical structure
relationship: connects UBERON:0000464 {cardinality="2"} ! anatomical space
relationship: has_part UBERON:0013686 ! anatomical conduit space
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751
property_value: UBPROP:0000012 "FMA has both conduit and conduit space. In EHDAA2 this is a surface feature" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0004118
name: vasculature of iris
namespace: uberon
def: "A vasculature that is part of a iris [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "iris blood vessels" EXACT [ZFA:0005568]
synonym: "iris vascular network" EXACT [OBOL:automatic]
synonym: "iris vasculature" EXACT []
synonym: "vascular network of iris" EXACT [OBOL:automatic]
xref: ZFA:0005568
is_a: UBERON:0002203 ! vasculature of eye
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0001769 ! iris
relationship: part_of UBERON:0001769 ! iris

[Term]
id: UBERON:0004119
name: endoderm-derived structure
namespace: uberon
def: "An anatomical structure that develops (entirely or partially) from the endoderm." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
is_a: UBERON:0000061 ! anatomical structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: develops_from UBERON:0000925 ! endoderm
relationship: develops_from UBERON:0000925 ! endoderm
property_value: curator_notes "Grouping term for query purposes" xsd:string

[Term]
id: UBERON:0004120
name: mesoderm-derived structure
namespace: uberon
def: "An anatomical structure that develops (entirely or partially) from the mesoderm." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "mesodermal derivative" EXACT [FBbt:00025998]
is_a: UBERON:0000061 ! anatomical structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: develops_from UBERON:0000926 ! mesoderm
relationship: develops_from UBERON:0000926 ! mesoderm
property_value: curator_notes "Grouping term for query purposes" xsd:string

[Term]
id: UBERON:0004121
name: ectoderm-derived structure
namespace: uberon
def: "An anatomical structure that develops (entirely or partially) from the ectoderm." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "ectodermal deriviative" EXACT [FBbt:00025990]
is_a: UBERON:0000061 ! anatomical structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: develops_from UBERON:0000924 ! ectoderm
relationship: develops_from UBERON:0000924 ! ectoderm
property_value: curator_notes "Grouping term for query purposes" xsd:string

[Term]
id: UBERON:0004122
name: genitourinary system
namespace: uberon
def: "Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction." [VHOG:0000286]
subset: efo_slim
subset: pheno_slim
synonym: "genito-urinary system" RELATED [FMA:280610]
synonym: "genitourinary tract" RELATED []
synonym: "GU tract" RELATED []
synonym: "UG tract" RELATED []
synonym: "urogenital system" EXACT []
synonym: "urogenital tract" RELATED [BTO:0003091]
synonym: "Urogenitalsystem" RELATED [BTO:0003091]
xref: AAO:0000624
xref: BILA:0000122
xref: BTO:0003091
xref: EFO:0003864
xref: EHDAA:1013
xref: EMAPA:16367
xref: EV:0100094
xref: FMA:280610
xref: GAID:362
xref: galen:GenitoUrinarySystem
xref: MESH:D014566
xref: NCIT:C12810
xref: SCTID:278861008
xref: UMLS:C0042066 {source="ncithesaurus:Genitourinary_System"}
xref: VHOG:0000286
xref: XAO:0000140
is_a: UBERON:0000467 ! anatomical system
intersection_of: UBERON:0000467 ! anatomical system
intersection_of: has_part UBERON:0000990 ! reproductive system
intersection_of: has_part UBERON:0001008 ! renal system
relationship: develops_from UBERON:0003064 {gci_relation="part_of", gci_filler="NCBITaxon:7742", source="AAO", source="https://github.com/geneontology/go-ontology/issues/16143"} ! intermediate mesoderm
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: has_part UBERON:0000990 ! reproductive system
relationship: has_part UBERON:0001008 ! renal system
property_value: UBPROP:0000001 "Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000624", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000002 "relationship type change: differentiates_from intermediate mesoderm (AAO:0010575) CHANGED TO: develops_from intermediate mesoderm (UBERON:0003064)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000624", ontology="AAO"}
property_value: UBPROP:0000003 "Kidneys and gonads (of vertebrates) develop from adjacent tissues, and after the excretory or urinary ducts have developed, the reproductive system usually taps into them or their derivatives.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000286", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.633", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "genitourinary" xsd:string
property_value: UBPROP:0000007 "urogenital" xsd:string

[Term]
id: UBERON:0004123
name: myocardial layer
namespace: uberon
def: "Any of the layers of the myocardium. Example: compact layer, trabecular layer." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
subset: pheno_slim
synonym: "layer of myocardium" EXACT []
synonym: "myocardium layer" EXACT []
xref: EMAPA:37475 {source="MA:th"}
xref: MA:0000080
is_a: UBERON:0005983 ! heart layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: layer_part_of UBERON:0002349 ! myocardium
relationship: layer_part_of UBERON:0002349 ! myocardium
relationship: part_of UBERON:0002349 ! myocardium

[Term]
id: UBERON:0004124
name: myocardium trabecular layer
namespace: uberon
def: "The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the endocardium. In zebrafish, unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae have more strut-like character, and are more uniform without apparent regional differences[ZFA]." [ZFA:0005059]
subset: efo_slim
subset: vertebrate_core
synonym: "heart muscle trabecula" RELATED []
synonym: "heart muscle trabeculae" RELATED OMO:0003004 []
synonym: "myocardial trabeculae carneae" RELATED OMO:0003004 []
synonym: "myocardial trabecular layer" EXACT []
synonym: "trabecula of heart muscle" RELATED []
synonym: "trabeculae" RELATED [TAO:0005059]
synonym: "trabecular layer" EXACT [ZFA:0005059]
xref: EFO:0003706
xref: MA:0002866
xref: TAO:0005059
xref: ZFA:0005059
is_a: UBERON:0004123 ! myocardial layer
intersection_of: UBERON:0004123 ! myocardial layer
intersection_of: adjacent_to UBERON:0002165 ! endocardium
intersection_of: composed_primarily_of GO:0036194 ! muscle cell projection
relationship: adjacent_to UBERON:0002165 ! endocardium
relationship: composed_primarily_of GO:0036194 ! muscle cell projection
property_value: UBPROP:0000001 "The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the the endocardium. Unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae of the zebrafish have more strut-like character, and are more uniform without apparent regional differences Hu et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005059", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0004126
name: trabecular layer of ventricle
namespace: uberon
def: "A myocardium trabecular layer that is part of a cardiac ventricle." [OBOL:automatic]
subset: vertebrate_core
synonym: "myocardium of region of ventricle" EXACT [FMA:83511]
synonym: "trabecular cardiac ventricle muscle" EXACT [GO:0003222]
synonym: "ventricular trabecular myocardium" EXACT [GO:0003222]
xref: FMA:83511
xref: TAO:0005060
xref: ZFA:0005060
is_a: UBERON:0004124 ! myocardium trabecular layer
intersection_of: UBERON:0004124 ! myocardium trabecular layer
intersection_of: part_of UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0001083 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! myocardium of ventricle
property_value: editor_note "TODO - check FMA" xsd:string

[Term]
id: UBERON:0004128
name: optic vesicle
namespace: uberon
def: "The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]." [GO:0003404, Wikipedia:Optic_vesicles]
comment: Genes: Six3, Pax6, Rx1 are expressed together in the tip of the neural plate [ISBN:9780878932504 "Developmental Biology"]. Development notes: During subsequent develop- ment, the optic vesicle invaginates and becomes a two-layered structure with an inner neural retina and outer retinal pigment epithelium. As soon as the developing optic vesicle makes contact with the overlying ectoderm, it induces the ectoderm to thicken and form the lens placode [PMID:16496288]
subset: pheno_slim
subset: vertebrate_core
synonym: "evagination" RELATED []
synonym: "eye vesicle" RELATED [XAO:0000228]
synonym: "ocular vesicle" RELATED [VHOG:0000165]
synonym: "optic vesicles" RELATED OMO:0003004 [ZFA:0000050]
xref: AAO:0011039
xref: EHDAA2:0001320
xref: EMAPA:16540
xref: FMA:293357
xref: NCIT:C34236
xref: SCTID:362864008
xref: TAO:0000050
xref: UMLS:C0231106 {source="ncithesaurus:Optic_Vesicle"}
xref: VHOG:0000165
xref: Wikipedia:Optic_vesicles
xref: XAO:0000228
xref: ZFA:0000050
is_a: UBERON:0000479 ! tissue
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: developmentally_induced_by UBERON:0004880 ! chordamesoderm
relationship: develops_from UBERON:0002346 {source="GO-def"} ! neurectoderm
relationship: develops_from UBERON:0003071 {source="ZFA"} ! eye primordium
relationship: part_of UBERON:0010312 {source="ZFA"} ! immature eye
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png" xsd:anyURI
property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000165", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004133
name: salivatory nucleus
namespace: uberon
def: "Missing definition for term UBERON:0004133. Please replace it using linked reference." [GO:0021751]
synonym: "salivary nucleus" EXACT [GO:0021751]
is_a: UBERON:0006331 ! brainstem nucleus
is_a: UBERON:0009662 ! hindbrain nucleus
relationship: part_of UBERON:0000988 ! pons

[Term]
id: UBERON:0004139
name: cardiogenic plate
namespace: uberon
def: "The first recognizable structure derived from the heart field." [GO:0003142]
subset: pheno_slim
synonym: "cardiac crescent" RELATED [EMAPA:16106]
synonym: "cardiogenic crescent" RELATED [GO:0003142]
synonym: "heart rudiment" RELATED []
synonym: "myocardial plate" EXACT [EHDAA2:0000215]
xref: EHDAA2:0000215
xref: EMAPA:16106
xref: VHOG:0000975
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0003084 ! heart primordium
property_value: editor_note "TODO - check plate vs rudiment vs primordium vs endocardial tube. See XAO" xsd:string
property_value: UBPROP:0000003 "(In vertebrates) The embryonic mesoderm is the source of both the cardiogenic plate, giving rise to the future myocardium as well as the endocardium that will line the system on the inner side.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000975", ontology="VHOG", source="PMID:15611355 Gittenberger-de Groot AC, Bartelings MM, Deruiter MC, Poelmann RE, Basics of cardiac development for the understanding of congenital heart malformations. Pediatric Research (2005)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004140
name: primary heart field
namespace: uberon
def: "A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle." [GO:0003138, GOC:mtg_heart, GOC:rl]
synonym: "FHF" RELATED OMO:0003000 [XAO:0004185]
synonym: "first heart field" EXACT [XAO:0004185]
synonym: "heart field" RELATED [XAO:0004185]
synonym: "PHF" RELATED OMO:0003000 [XAO:0004185]
synonym: "primary heart field" EXACT [PMID:17276708, XAO:0004185]
xref: XAO:0004185
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007688 ! anlage
relationship: part_of UBERON:0003081 {source="GO:0003128"} ! lateral plate mesoderm
relationship: part_of UBERON:0036146 {source="https://orcid.org/0000-0003-3308-6245"} ! cardiopharyngeal field
property_value: UBPROP:0000012 "this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138]" xsd:string {external_ontology="GO"}

[Term]
id: UBERON:0004141
name: heart tube
namespace: uberon
def: "An epithelial tube that will give rise to the mature heart." [GO:0003143, GOC:mtg_heart]
subset: efo_slim
subset: pheno_slim
subset: vertebrate_core
synonym: "embryonic heart tube" EXACT [GO:0003143]
synonym: "endocardial heart tube" EXACT [MP:0012700]
synonym: "endocardial tube" EXACT [XAO:0000337]
xref: AAO:0010411
xref: EFO:0003526
xref: EMAPA:32685
xref: NCIT:C34161
xref: TAO:0000360
xref: XAO:0000337
xref: ZFA:0000360
is_a: UBERON:0003914 ! epithelial tube
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0012275 ! meso-epithelium
relationship: develops_from UBERON:0005498 ! primitive heart tube
relationship: immediate_transformation_of UBERON:0005498 {source="ZFA-modified"} ! primitive heart tube
property_value: UBPROP:0000001 "the paired, longitudinal, endothelial-lined channels formed from the cardiogenic mesoderm in embryonic development; angiogenic cell clusters (aka angioblastic cords) located in a horse-shoe shape configuration in the cardiogenic plate coalesce to form the right and left endocardial heart tubes which then fuse in cephalo-caudal direction to form a single primitive heart tube." xsd:string {source="MP:0012700"}

[Term]
id: UBERON:0004142
name: outflow tract septum
namespace: uberon
def: "The outflow tract septum is a partition in the outflow tract." [GO:0003148]
xref: XAO:0004141
is_a: UBERON:0002099 ! cardiac septum
intersection_of: UBERON:0002099 ! cardiac septum
intersection_of: part_of UBERON:0004145 ! outflow tract
relationship: part_of UBERON:0004145 ! outflow tract

[Term]
id: UBERON:0004145
name: outflow tract
namespace: uberon
def: "The outflow tract is the portion of the heart through which blood flows into the arteries." [GO:0003151]
subset: pheno_slim
synonym: "arterial (outflow) pole" RELATED [PMID:20735616]
synonym: "cardiac outflow tract" EXACT [PMID:20735616]
synonym: "heart outflow tract" EXACT []
xref: EHDAA2:0001351
xref: EHDAA:464
xref: EHDAA:798
xref: EMAPA:16346
xref: MA:0000100
xref: VHOG:0000670
xref: XAO:0004139
is_a: UBERON:0004111 ! anatomical conduit
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: channel_for UBERON:0000178 ! blood
relationship: channels_from UBERON:0000948 ! heart
relationship: channels_into UBERON:0001637 ! artery
relationship: part_of UBERON:0000948 ! heart
property_value: UBPROP:0000008 "Depending on the species, attached at the cardiac outflow are described the conus arteriosus, the truncus arteriosus and, or the bulbus arteriosus. At the distal limit of these outflow structures, but lying outside the pericardial cavity, is the ventral aorta[PMID:20735616]" xsd:string

[Term]
id: UBERON:0004146
name: His-Purkinje system
namespace: uberon
def: "The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." [GO:0003164, https://github.com/geneontology/go-ontology/issues/12451]
synonym: "His-Purkinji network" EXACT []
synonym: "HPS" EXACT OMO:0003000 []
synonym: "VCS" EXACT []
synonym: "ventricular conduction system" EXACT []
is_a: UBERON:0010131 {source="cjm"} ! conducting tissue of heart
is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle
relationship: only_in_taxon NCBITaxon:32523 {source="PMID:12626327", source="PMID:21234997", source="github:michaelerice"} ! Tetrapoda
relationship: part_of UBERON:0002350 {source="GO"} ! conducting system of heart
property_value: UBPROP:0000001 "the intraventricular conduction system from the bundle of His to the distal Purkinje fibers, which carries the impulse to the ventricles." xsd:string {source="http://medical-dictionary.thefreedictionary.com/His-Purkinje+system"}

[Term]
id: UBERON:0004148
name: cardiac vein
namespace: uberon
def: "Vein of heart that drains the myocardium." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "cardiac vein" EXACT [FMA:12846]
synonym: "coronary vein" EXACT [ZFA:0005814]
synonym: "coronary vein" RELATED [Wikipedia:Coronary_circulation]
synonym: "heart vein" EXACT [OBOL:automatic]
synonym: "vein of heart" EXACT [OBOL:automatic]
xref: EHDAA2:0004507
xref: EMAPA:37137 {source="MA:th"}
xref: FMA:12846
xref: galen:CoronaryVein
xref: NCIT:C12878
xref: NCIT:C12882
xref: SCTID:277726009
xref: UMLS:C0226654 {source="ncithesaurus:Cardiac_Vein"}
xref: UMLS:C0226737 {source="ncithesaurus:Coronary_Vein"}
xref: Wikipedia:Coronary_circulation
xref: ZFA:0005814
is_a: UBERON:0003498 ! heart blood vessel
is_a: UBERON:0005194 ! thoracic vein
is_a: UBERON:0013140 {source="FMA"} ! systemic vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0002349 ! myocardium
intersection_of: part_of UBERON:0000948 ! heart
relationship: drains UBERON:0002349 ! myocardium
relationship: part_of RO:0002577 ! system
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI

[Term]
id: UBERON:0004151
name: cardiac chamber
namespace: uberon
def: "A cardiac chamber surrounds an enclosed cavity within the heart." [GO:0003205]
comment: generic enough to cover FBbt:00003156 heart chamber but this is a cavity. GO defines it as the cavity. TODO - move subclasses. Note this also includes sinus venosus
synonym: "chamber of heart" EXACT []
synonym: "heart chamber" EXACT []
xref: FMA:7095
xref: SCTID:276456008
is_a: UBERON:0000064 ! organ part
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: part_of UBERON:0000948 ! heart

[Term]
id: UBERON:0004160
name: proepicardium
namespace: uberon
def: "An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium." [GO:0003342, http://en.wiktionary.org/wiki/proepicardium]
synonym: "proepicardial cluster" EXACT [ZFA:0005808]
synonym: "proepicardial organ" EXACT [ZFIN:ZDB-PUB-080218-16]
xref: EMAPA:36025
xref: ZFA:0005808
is_a: UBERON:0003104 ! mesenchyme
relationship: part_of UBERON:0004161 {notes="todo check other taxa"} ! septum transversum
relationship: part_of UBERON:0004535 {source="ZFA"} ! cardiovascular system
property_value: UBPROP:0000007 "propepicardial" xsd:string
property_value: UBPROP:0000008 "Proepicardial clusters in Zebrafish form on the pericardial wall, adjacent to the atrioventricular (AV) junction and near the venous pole[ZFA]" xsd:string

[Term]
id: UBERON:0004161
name: septum transversum
namespace: uberon
def: "A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]." [VHOG:0000019, Wikipedia:Septum_transversum]
subset: pheno_slim
synonym: "transverse septum" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: EHDAA2:0001829
xref: EHDAA:736
xref: EMAPA:16318
xref: FMA:295593
xref: NCIT:C34296
xref: SCTID:308819008
xref: UMLS:C0231004 {source="ncithesaurus:Septum_Transversum"}
xref: VHOG:0000019
xref: Wikipedia:Septum_transversum
is_a: UBERON:0003104 ! mesenchyme
relationship: located_in UBERON:0002323 ! coelemic cavity lumen
relationship: part_of UBERON:0002100 ! trunk
property_value: UBPROP:0000001 "A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000019", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/transverse+septum"}
property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart (of other tetrapods) is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes) Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000019", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "The cranial part of the septum transversum gives rise to the central tendon of the diaphragm and is the origin of the myoblasts that invade the pleuroperitoneal folds resulting in the formation of the muscular diaphragm. The caudal part of the septum transversum is invaded by the hepatic diverticulum which divides within it to form the liver and thus gives rise to the ventral mesentery of the foregut." xsd:string
property_value: UBPROP:0000012 "in EHDAA2 this is divided into mesenchymal portion and hepatic diverticulum" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0004175
name: internal genitalia
namespace: uberon
def: "The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [GO:0035260]
comment: TODO: make a subdivision of reproductive system. Relabel. See https://github.com/obophenotype/uberon/issues/547
subset: human_reference_atlas
subset: organ_slim
subset: pheno_slim
synonym: "internal genitalia" EXACT []
synonym: "internal genitals" EXACT []
synonym: "internal reproductive organ" RELATED []
synonym: "internal sex organ" RELATED []
xref: FMA:45652
is_a: UBERON:0003133 ! reproductive organ
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004176
name: external genitalia
namespace: uberon
def: "The external genitalia are the outer sex organs, such as the penis or vulva in mammals." [GO:0035261]
comment: TODO: make a subdivision of reproductive system. Relabel. See https://github.com/obophenotype/uberon/issues/547
subset: organ_slim
subset: pheno_slim
synonym: "external genitalia" EXACT []
synonym: "external reproductive organ" RELATED []
synonym: "external sex organ" RELATED []
xref: FMA:45643
xref: SCTID:362207005
is_a: UBERON:0003133 ! reproductive organ

[Term]
id: UBERON:0004177
name: hemopoietic organ
namespace: uberon
def: "Organ that is part of the hematopoietic system." [GOC:Obol]
subset: organ_slim
subset: pheno_slim
synonym: "haematological system organ" EXACT [OBOL:automatic]
synonym: "haemopoietic system organ" EXACT [OBOL:automatic]
synonym: "hematopoeitic or lymphoid organ" NARROW []
synonym: "hematopoeitic organ" EXACT []
synonym: "hematopoietic system organ" EXACT [OBOL:automatic]
synonym: "lymph organ" NARROW [MA:0000747]
synonym: "lymphoid organ" NARROW [BTO:0004605, FMA:7143]
synonym: "organ of haematological system" EXACT [OBOL:automatic]
synonym: "organ of haemopoietic system" EXACT [OBOL:automatic]
synonym: "organ of hematopoietic system" EXACT [OBOL:automatic]
synonym: "organ of organa haemopoietica" EXACT [OBOL:automatic]
synonym: "organa haemopoietica organ" EXACT [OBOL:automatic]
xref: BTO:0004605
xref: EMAPA:37665 {source="MA:th"}
xref: FMA:7143
xref: MA:0000747
xref: SCTID:361338006
is_a: UBERON:0000062 ! organ
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000062 ! organ
intersection_of: part_of UBERON:0002390 ! hematopoietic system
relationship: part_of UBERON:0002390 ! hematopoietic system
property_value: editor_note "consider splitting out lymph organ, compare with lymph node" xsd:string
property_value: UBPROP:0000001 "the organs in which the formed elements of the blood and lymph are produced[http://encyclopedia2.thefreedictionary.com/Hematopoietic+Organs]." xsd:string {source="http://encyclopedia2.thefreedictionary.com/Hematopoietic+Organs"}
property_value: UBPROP:0000012 "the FMA class 'lymphoid organ' is a general anatomical term" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0004178
name: aorta smooth muscle tissue
namespace: uberon
def: "The nonstriated, involuntary muscle tissue located in the wall of the aorta." [MGI:csmith, MP:0009865]
subset: efo_slim
subset: pheno_slim
synonym: "aorta non-striated muscle" EXACT [OBOL:automatic]
synonym: "aorta smooth muscle" EXACT [OBOL:automatic]
synonym: "aortic smooth muscle" EXACT [BTO:0001685]
xref: BTO:0001685
xref: CALOHA:TS-0048
xref: EFO:0002775
xref: EMAPA:35135
xref: MA:0000702
xref: NCIT:C49191
xref: UMLS:C1706825 {source="ncithesaurus:Aorta_Smooth_Muscle_Tissue"}
is_a: UBERON:0004237 ! blood vessel smooth muscle
is_a: UBERON:0004695 ! arterial system smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0000947 ! aorta
relationship: part_of UBERON:0000947 ! aorta

[Term]
id: UBERON:0004183
name: placental labyrinth blood vessel
namespace: uberon
def: "The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." [GO:0060716]
synonym: "blood vessel of labyrinthine layer" EXACT [OBOL:automatic]
synonym: "blood vessel of labyrinthine layer of placenta" EXACT [OBOL:automatic]
synonym: "blood vessel of placenta labyrinth" EXACT [OBOL:automatic]
synonym: "labyrinthine layer blood vessel" EXACT [GO:0060716]
synonym: "labyrinthine layer of placenta blood vessel" EXACT [OBOL:automatic]
synonym: "placenta labyrinth blood vessel" EXACT [OBOL:automatic]
is_a: UBERON:0022358 ! placenta blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0003946 ! placenta labyrinth
relationship: part_of UBERON:0003970 ! placental labyrinth vasculature

[Term]
id: UBERON:0004185
name: endodermal part of digestive tract
namespace: uberon
def: "A portions of the gut that is derived from endoderm." [GO:0061031]
synonym: "endodermal gut" EXACT []
synonym: "gut endoderm" EXACT [EMAPA:32930]
xref: EMAPA:32930
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0004921 ! subdivision of digestive tract
intersection_of: UBERON:0004921 ! subdivision of digestive tract
intersection_of: develops_from UBERON:0000925 ! endoderm
intersection_of: part_of UBERON:0001555 ! digestive tract

[Term]
id: UBERON:0004203
name: cortical collecting duct
namespace: uberon
alt_id: UBERON:0005267
def: "The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex." [GO:0072059]
subset: human_reference_atlas
synonym: "kidney cortex collecting duct" EXACT [MA:0002600]
synonym: "renal cortex collecting duct" RELATED [MA:0002600]
xref: BTO:0002643
xref: EMAPA:28130
xref: MA:0002600
is_a: UBERON:0013522 ! subdivision of tube
intersection_of: UBERON:0013522 ! subdivision of tube
intersection_of: part_of UBERON:0001225 ! cortex of kidney
intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule
relationship: part_of UBERON:0001225 ! cortex of kidney
relationship: part_of UBERON:0001232 ! collecting duct of renal tubule
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004208
name: nephrogenic mesenchyme
namespace: uberon
def: "Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GO:0072076]
comment: The detailed events associated with the differentiation of the nephrogenic mesenchyme are somewhat complex. It has been suggested that each terminal branch of the ureteric bud stimulates the associated cap mesenchyme tissue to form a renal vesicle (the most primitive stage of nephron development: a stage I nephron). This then elongates, becomes a comma-shaped and then an S-shaped body (stage II nephron), and makes contact with and fuses with the distal component of the ureteric bud. The latter then forms the collecting duct. One fold of the S-shaped body gives rise to Bowman's capsule (also termed the glomerular capsule). Soon afterwards, endothelial cells invade to make a capillary knot-like outgrowth, the glomerular tuft, which goes on to form the glomerulus. The inner epithelial layer of the Bowman's capsule (also called the visceral epithelium, or podocyte layer because it consists of podocytes) is closely apposed to the endothelial glomerulus. Together, the Bowman's capsule and the glomerulus comprise the definitive renal corpuscle. The rest of the nephron elongates to form components of the proximal tubule, the loop of Henle and the distal tubule. The distal pole of the developing nephron connects to the ureteric bud that induced it at an early stage of nephron/ collecting duct development, before differentiation of the proximal tubule, the loop of Henle and the distal tubule are complete. This connection allows the excretory products produced by the kidney to be removed and subsequently transferred, via the ureter, into the bladder where they are stored until it is appropriate to empty the bladder. [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron]
synonym: "mesenchyme of nephron" EXACT [OBOL:automatic]
synonym: "nephron mesenchyme" EXACT [OBOL:automatic]
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: has_potential_to_develop_into UBERON:0001285 ! nephron
relationship: has_potential_to_develop_into UBERON:0001285 ! nephron

[Term]
id: UBERON:0004209
name: renal vesicle
namespace: uberon
def: "The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GO:0072077]
synonym: "stage I nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Renal_vesicle.html, ZFA:0005586]
is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle
relationship: developmentally_induced_by UBERON:0000084 ! ureteric bud
relationship: develops_from UBERON:0004208 ! nephrogenic mesenchyme
relationship: has_potential_to_develop_into UBERON:0004211 ! nephron epithelium
relationship: part_of UBERON:0010536 ! nephron progenitor
property_value: editor_note "note that this class includes both metanephric and mesonephric vesicles - ZFA and EHDAA2 associations are placed with these classes. TODO - make a more specific develops_from relationship - see UBERON:0005107 ! metanephric cap" xsd:string

[Term]
id: UBERON:0004211
name: nephron epithelium
namespace: uberon
def: "The nephron epithelium is a tissue that covers the surface of a nephron." [GO:0072088]
synonym: "epithelial tissue of nephron" EXACT [OBOL:automatic]
synonym: "epithelium of nephron" EXACT [OBOL:automatic]
synonym: "nephron epithelial tissue" EXACT [OBOL:automatic]
is_a: UBERON:0004819 ! kidney epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001285 ! nephron
relationship: part_of UBERON:0001285 ! nephron

[Term]
id: UBERON:0004215
name: back nerve
namespace: uberon
def: "A nerve that is part of a back [Automatically generated definition]." [OBOL:automatic]
synonym: "nerve of back" EXACT [OBOL:automatic]
xref: EMAPA:37268 {source="MA:th"}
xref: MA:0000497
is_a: UBERON:0001021 ! nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: part_of UBERON:0001137 ! dorsum
relationship: part_of UBERON:0001137 ! dorsum

[Term]
id: UBERON:0004219
name: urethra smooth muscle layer
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a urethra [Automatically generated definition]." [OBOL:automatic]
synonym: "muscle layer of urethra" EXACT [FMA:76909]
synonym: "muscular coat of urethra" EXACT [FMA:76909]
synonym: "muscular layer of urethra" EXACT [FMA:76909]
synonym: "smooth muscle of urethra" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of urethra" EXACT [OBOL:automatic]
synonym: "tunica muscularis urethrae" EXACT OMO:0003011 [FMA:TA]
synonym: "urethra smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "urethral smooth muscle" RELATED [MA:0001691]
xref: EMAPA:36630
xref: FMA:76909
xref: MA:0001691
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0000057 ! urethra
relationship: part_of UBERON:0000057 ! urethra

[Term]
id: UBERON:0004220
name: large intestine smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a large intestine [Automatically generated definition]." [OBOL:automatic]
synonym: "involuntary muscle of large intestine" EXACT [OBOL:automatic]
synonym: "large intestine involuntary muscle" EXACT [OBOL:automatic]
synonym: "large intestine non-striated muscle" EXACT [OBOL:automatic]
synonym: "large intestine smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "non-striated muscle of large intestine" EXACT [OBOL:automatic]
synonym: "smooth muscle of large intestine" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of large intestine" EXACT [OBOL:automatic]
xref: EMAPA:35469
xref: MA:0001547
is_a: UBERON:0004221 ! intestine smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0000059 ! large intestine
relationship: overlaps UBERON:0011198 {notes="consider merging"} ! muscle layer of large intestine
relationship: part_of UBERON:0001169 {source="MA"} ! wall of large intestine
property_value: UBPROP:0000012 "MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0004221
name: intestine smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a intestine [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "bowel involuntary muscle" EXACT [OBOL:automatic]
synonym: "bowel non-striated muscle" EXACT [OBOL:automatic]
synonym: "bowel smooth muscle" EXACT [OBOL:automatic]
synonym: "bowel smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "intestinal muscularis" RELATED [EMAPA:35441]
synonym: "intestinal smooth muscle" RELATED [BTO:0000643]
synonym: "intestine involuntary muscle" EXACT [OBOL:automatic]
synonym: "intestine non-striated muscle" EXACT [OBOL:automatic]
synonym: "intestine smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "involuntary muscle of bowel" EXACT [OBOL:automatic]
synonym: "involuntary muscle of intestine" EXACT [OBOL:automatic]
synonym: "non-striated muscle of bowel" EXACT [OBOL:automatic]
synonym: "non-striated muscle of intestine" EXACT [OBOL:automatic]
synonym: "smooth muscle of bowel" EXACT [OBOL:automatic]
synonym: "smooth muscle of intestine" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of bowel" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of intestine" EXACT [OBOL:automatic]
xref: BTO:0000643
xref: EMAPA:35441
xref: EMAPA:35443
xref: MA:0001539
xref: NCIT:C49243
xref: UMLS:C1708547 {source="ncithesaurus:Intestinal_Smooth_Muscle_Tissue"}
is_a: UBERON:0004226 ! gastrointestinal system smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0000160 ! intestine
relationship: contributes_to_morphology_of UBERON:0000160 ! intestine
relationship: overlaps UBERON:0012367 {notes="consider merging"} ! muscle layer of intestine
relationship: part_of UBERON:0001262 ! wall of intestine
property_value: UBPROP:0000012 "MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0004222
name: stomach smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a stomach [Automatically generated definition]." [OBOL:automatic]
synonym: "gastric muscle" RELATED [BTO:0001818]
synonym: "gastric smooth muscle" RELATED [MA:0001627]
synonym: "involuntary muscle of stomach" EXACT [OBOL:automatic]
synonym: "involuntary muscle of ventriculus" EXACT [OBOL:automatic]
synonym: "non-striated muscle of stomach" EXACT [OBOL:automatic]
synonym: "non-striated muscle of ventriculus" EXACT [OBOL:automatic]
synonym: "smooth muscle of stomach" EXACT [OBOL:automatic]
synonym: "smooth muscle of ventriculus" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of stomach" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of ventriculus" EXACT [OBOL:automatic]
synonym: "stomach involuntary muscle" EXACT [OBOL:automatic]
synonym: "stomach muscle" RELATED [BTO:0001818]
synonym: "stomach non-striated muscle" EXACT [OBOL:automatic]
synonym: "stomach smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "ventriculus involuntary muscle" EXACT [OBOL:automatic]
synonym: "ventriculus non-striated muscle" EXACT [OBOL:automatic]
synonym: "ventriculus smooth muscle" EXACT [OBOL:automatic]
synonym: "ventriculus smooth muscle tissue" EXACT [OBOL:automatic]
xref: BTO:0001818
xref: EMAPA:35823
xref: MA:0001627
is_a: UBERON:0004226 ! gastrointestinal system smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0000945 ! stomach
relationship: part_of UBERON:0001167 ! wall of stomach

[Term]
id: UBERON:0004224
name: muscular coat of vas deferens
namespace: uberon
def: "A muscular coat that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic]
synonym: "muscle layer of deferent duct" EXACT [FMA:19239]
synonym: "muscle layer of ductus deferens" EXACT [FMA:19239]
synonym: "muscle layer of vas deferens" EXACT [FMA:19239]
synonym: "muscular coat of ductus deferens" EXACT [FMA:19239]
synonym: "muscular layer of ductus deferens" EXACT [FMA:19239]
synonym: "muscularis of vas deferens" EXACT [FMA:19239]
synonym: "tunica muscularis (ductus deferens)" EXACT [FMA:19239]
synonym: "tunica muscularis ductus deferentis" EXACT OMO:0003011 [FMA:19239, FMA:TA]
xref: EMAPA:29270
xref: FMA:19239
xref: MA:0001750
xref: SCTID:299705008
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0006660 ! muscular coat
is_a: UBERON:0034933 ! layer of smooth muscle tissue
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0001000 ! vas deferens
relationship: part_of UBERON:0001000 ! vas deferens
property_value: editor_note "TODO - check MA and FMA classes mean the same thing" xsd:string

[Term]
id: UBERON:0004225
name: respiratory system smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "airway smooth muscle" RELATED [BTO:0001660]
synonym: "airway smooth muscle cell" RELATED [BTO:0001660]
synonym: "respiratory smooth muscle" EXACT [BTO:0001660]
synonym: "smooth muscle of respiratory system" EXACT [OBOL:automatic]
xref: BTO:0001660
xref: EMAPA:35734
xref: MA:0001830
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0004226
name: gastrointestinal system smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a digestive system [Automatically generated definition]." [OBOL:automatic]
synonym: "smooth muscle tissue of gastrointestinal system" EXACT [OBOL:automatic]
xref: EMAPA:35117
xref: MA:0001523
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system
relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system

[Term]
id: UBERON:0004227
name: kidney pelvis smooth muscle
namespace: uberon
def: "The smooth muscle tissue surrounding the urothelium of the kidney pelvis." [MGI:csmith, MP:0011335]
subset: pheno_slim
synonym: "kidney pelvis smooth muscle" EXACT [EMAPA:28120]
synonym: "pelvic smooth muscle" RELATED [EMAPA:28120]
synonym: "renal pelvis smooth muscle" EXACT [EMAPA:28120]
synonym: "smooth muscle tissue of renal pelvis" EXACT [FMA:262022]
xref: EMAPA:28120
xref: FMA:262022
xref: MA:0002631
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001224 ! renal pelvis
relationship: contributes_to_morphology_of UBERON:0001224 ! renal pelvis
relationship: part_of UBERON:0001224 ! renal pelvis

[Term]
id: UBERON:0004228
name: urinary bladder smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic]
synonym: "bladder involuntary muscle" EXACT [OBOL:automatic]
synonym: "bladder non-striated muscle" EXACT [OBOL:automatic]
synonym: "bladder smooth muscle" EXACT [OBOL:automatic]
synonym: "bladder smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "involuntary muscle of bladder" EXACT [OBOL:automatic]
synonym: "involuntary muscle of urinary bladder" EXACT [OBOL:automatic]
synonym: "non-striated muscle of bladder" EXACT [OBOL:automatic]
synonym: "non-striated muscle of urinary bladder" EXACT [OBOL:automatic]
synonym: "smooth muscle layer of bladder" RELATED []
synonym: "smooth muscle of bladder" EXACT [OBOL:automatic]
synonym: "smooth muscle of urinary bladder" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of bladder" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of urinary bladder" EXACT [OBOL:automatic]
synonym: "urinary bladder involuntary muscle" EXACT [OBOL:automatic]
synonym: "urinary bladder muscle" EXACT [MA:0001697]
synonym: "urinary bladder non-striated muscle" EXACT [OBOL:automatic]
synonym: "urinary bladder smooth muscle tissue" EXACT [OBOL:automatic]
xref: BTO:0001849
xref: CALOHA:TS-1087
xref: EMAPA:37791 {source="MA:th"}
xref: MA:0001697
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001255 ! urinary bladder
relationship: part_of UBERON:0001255 ! urinary bladder

[Term]
id: UBERON:0004231
name: anal region smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of an anal region [Automatically generated definition]." [OBOL:automatic]
synonym: "anal part of perineum involuntary muscle" EXACT [OBOL:automatic]
synonym: "anal part of perineum non-striated muscle" EXACT [OBOL:automatic]
synonym: "anal part of perineum smooth muscle" EXACT [OBOL:automatic]
synonym: "anal part of perineum smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "anal region involuntary muscle" EXACT [OBOL:automatic]
synonym: "anal region non-striated muscle" EXACT [OBOL:automatic]
synonym: "anal region smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "anal triangle involuntary muscle" EXACT [OBOL:automatic]
synonym: "anal triangle non-striated muscle" EXACT [OBOL:automatic]
synonym: "anal triangle smooth muscle" EXACT [OBOL:automatic]
synonym: "anal triangle smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "involuntary muscle of anal part of perineum" EXACT [OBOL:automatic]
synonym: "involuntary muscle of anal region" EXACT [OBOL:automatic]
synonym: "involuntary muscle of anal triangle" EXACT [OBOL:automatic]
synonym: "non-striated muscle of anal part of perineum" EXACT [OBOL:automatic]
synonym: "non-striated muscle of anal region" EXACT [OBOL:automatic]
synonym: "non-striated muscle of anal triangle" EXACT [OBOL:automatic]
synonym: "smooth muscle of anal part of perineum" EXACT [OBOL:automatic]
synonym: "smooth muscle of anal region" EXACT [OBOL:automatic]
synonym: "smooth muscle of anal triangle" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of anal part of perineum" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of anal region" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of anal triangle" EXACT [OBOL:automatic]
xref: EMAPA:37394 {source="MA:th"}
xref: MA:0001532
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001353 ! anal region
relationship: part_of UBERON:0001353 ! anal region

[Term]
id: UBERON:0004233
name: lower respiratory tract smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic]
synonym: "involuntary muscle of lower respiratory tract" EXACT [OBOL:automatic]
synonym: "lower respiratory tract involuntary muscle" EXACT [OBOL:automatic]
synonym: "lower respiratory tract non-striated muscle" EXACT [OBOL:automatic]
synonym: "lower respiratory tract smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "non-striated muscle of lower respiratory tract" EXACT [OBOL:automatic]
synonym: "smooth muscle of lower respiratory tract" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of lower respiratory tract" EXACT [OBOL:automatic]
xref: EMAPA:35520
xref: MA:0002410
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0004225 ! respiratory system smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001558 ! lower respiratory tract
relationship: part_of UBERON:0001558 ! lower respiratory tract

[Term]
id: UBERON:0004234
name: iris smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a iris [Automatically generated definition]." [OBOL:automatic]
synonym: "involuntary muscle of iris" EXACT [OBOL:automatic]
synonym: "iridial smooth muscle" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "iris involuntary muscle" EXACT [OBOL:automatic]
synonym: "iris non-striated muscle" EXACT [OBOL:automatic]
synonym: "iris smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "non-striated muscle of iris" EXACT [OBOL:automatic]
synonym: "smooth muscle of iris" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of iris" EXACT [OBOL:automatic]
xref: BTO:0000655
xref: EMAPA:35448
xref: FMA:312338
xref: MA:0001270
is_a: UBERON:0003386 {source="MA"} ! smooth muscle of eye
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001769 ! iris
relationship: part_of UBERON:0001606 ! muscle of iris
property_value: editor_note "see notes for muscle of iris." xsd:string

[Term]
id: UBERON:0004236
name: arteriole smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of an arteriole [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:36287
xref: FMA:312251
xref: MA:0000706
is_a: UBERON:0004237 ! blood vessel smooth muscle
is_a: UBERON:0004695 ! arterial system smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001980 ! arteriole
relationship: part_of UBERON:0001980 ! arteriole

[Term]
id: UBERON:0004237
name: blood vessel smooth muscle
namespace: uberon
alt_id: UBERON:0010508
def: "Smooth muscle found within, and composing the majority of the wall of blood vessels." [Wikipedia:Vascular_smooth_muscle]
subset: human_reference_atlas
subset: pheno_slim
synonym: "blood vessel involuntary muscle" EXACT [OBOL:automatic]
synonym: "blood vessel non-striated muscle" EXACT [OBOL:automatic]
synonym: "blood vessel smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "involuntary muscle of blood vessel" EXACT [OBOL:automatic]
synonym: "non-striated muscle of blood vessel" EXACT [OBOL:automatic]
synonym: "smooth muscle of blood vessel" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of blood vessel" EXACT [OBOL:automatic]
synonym: "vascular smooth muscle" EXACT [ZFA:0005321]
synonym: "vascular smooth muscle tissue" EXACT []
xref: BTO:0001431
xref: CALOHA:TS-1107
xref: EMAPA:35177
xref: MA:0000710
xref: MESH:D009131
xref: NCIT:C33853
xref: TAO:0005321
xref: UMLS:C1519956 {source="ncithesaurus:Vascular_Smooth_Muscle_Tissue"}
xref: Wikipedia:Vascular_smooth_muscle
xref: ZFA:0005321
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001981 ! blood vessel
relationship: part_of UBERON:0001981 ! blood vessel
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000009 "Vascular smooth muscle contracts or relaxes to both change the volume of blood vessels and the local blood pressure, a mechanism that is responsible for the redistribution of the blood within the body to areas where it is needed (i.e. areas with temporarily enhanced oxygen consumption). Thus the main function of vascular smooth muscle tonus is to regulate the caliber of the blood vessels in the body. Excessive vasoconstriction leads to hypertension, while excessive vasodilation as in shock leads to hypotension." xsd:string

[Term]
id: UBERON:0004238
name: spleen smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a spleen [Automatically generated definition]." [OBOL:automatic]
synonym: "involuntary muscle of spleen" EXACT [OBOL:automatic]
synonym: "non-striated muscle of spleen" EXACT [OBOL:automatic]
synonym: "smooth muscle of spleen" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of spleen" EXACT [OBOL:automatic]
synonym: "spleen involuntary muscle" EXACT [OBOL:automatic]
synonym: "spleen non-striated muscle" EXACT [OBOL:automatic]
synonym: "spleen smooth muscle tissue" EXACT [OBOL:automatic]
xref: EMAPA:35807
xref: MA:0000757
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0002106 ! spleen
relationship: part_of UBERON:0002106 ! spleen

[Term]
id: UBERON:0004239
name: small intestine smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a small intestine [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "involuntary muscle of small bowel" EXACT [OBOL:automatic]
synonym: "involuntary muscle of small intestine" EXACT [OBOL:automatic]
synonym: "non-striated muscle of small bowel" EXACT [OBOL:automatic]
synonym: "non-striated muscle of small intestine" EXACT [OBOL:automatic]
synonym: "small bowel involuntary muscle" EXACT [OBOL:automatic]
synonym: "small bowel non-striated muscle" EXACT [OBOL:automatic]
synonym: "small bowel smooth muscle" EXACT [OBOL:automatic]
synonym: "small bowel smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "small intestine involuntary muscle" EXACT [OBOL:automatic]
synonym: "small intestine non-striated muscle" EXACT [OBOL:automatic]
synonym: "small intestine smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "smooth muscle of small bowel" EXACT [OBOL:automatic]
synonym: "smooth muscle of small intestine" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of small bowel" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of small intestine" EXACT [OBOL:automatic]
xref: EMAPA:35783
xref: MA:0001559
is_a: UBERON:0004221 ! intestine smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: overlaps UBERON:0011201 {notes="consider merging"} ! muscle layer of small intestine
relationship: part_of UBERON:0001168 ! wall of small intestine
property_value: UBPROP:0000012 "MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0004240
name: gallbladder smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic]
synonym: "biliary smooth muscle" RELATED [MA:0001635]
synonym: "gall bladder involuntary muscle" EXACT [OBOL:automatic]
synonym: "gall bladder non-striated muscle" EXACT [OBOL:automatic]
synonym: "gall bladder smooth muscle" EXACT [OBOL:automatic]
synonym: "gall bladder smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "gallbladder involuntary muscle" EXACT [OBOL:automatic]
synonym: "gallbladder non-striated muscle" EXACT [OBOL:automatic]
synonym: "gallbladder smooth muscle tissue" EXACT []
synonym: "involuntary muscle of gall bladder" EXACT [OBOL:automatic]
synonym: "involuntary muscle of gallbladder" EXACT [OBOL:automatic]
synonym: "non-striated muscle of gall bladder" EXACT [OBOL:automatic]
synonym: "non-striated muscle of gallbladder" EXACT [OBOL:automatic]
synonym: "smooth muscle of gall bladder" EXACT [OBOL:automatic]
synonym: "smooth muscle of gallbladder" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of gall bladder" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of gallbladder" EXACT [OBOL:automatic]
xref: EMAPA:35373
xref: MA:0001635
xref: NCIT:C49483
xref: UMLS:C1708179 {source="ncithesaurus:Gallbladder_Smooth_Muscle_Tissue"}
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0002110 ! gallbladder
relationship: part_of UBERON:0002110 ! gallbladder

[Term]
id: UBERON:0004245
name: oviduct smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a fallopian tube [Automatically generated definition]." [OBOL:automatic]
synonym: "fallopian tube involuntary muscle" EXACT [OBOL:automatic]
synonym: "fallopian tube non-striated muscle" EXACT [OBOL:automatic]
synonym: "fallopian tube smooth muscle" EXACT [OBOL:automatic]
synonym: "fallopian tube smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "involuntary muscle of fallopian tube" EXACT [OBOL:automatic]
synonym: "non-striated muscle of fallopian tube" EXACT [OBOL:automatic]
synonym: "smooth muscle of fallopian tube" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of fallopian tube" EXACT [OBOL:automatic]
xref: EMAPA:29046
xref: MA:0001721
is_a: UBERON:0001135 ! smooth muscle tissue
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0003889 ! fallopian tube
relationship: part_of UBERON:0003889 ! fallopian tube

[Term]
id: UBERON:0004246
name: outflow tract smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic]
synonym: "involuntary muscle of outflow tract" EXACT [OBOL:automatic]
synonym: "non-striated muscle of outflow tract" EXACT [OBOL:automatic]
synonym: "outflow tract involuntary muscle" EXACT [OBOL:automatic]
synonym: "outflow tract non-striated muscle" EXACT [OBOL:automatic]
synonym: "outflow tract smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "smooth muscle of outflow tract" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of outflow tract" EXACT [OBOL:automatic]
xref: EMAPA:37708 {source="MA:th"}
xref: MA:0000492
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0004145 ! outflow tract
relationship: part_of UBERON:0004145 ! outflow tract

[Term]
id: UBERON:0004247
name: bone of dorsum
namespace: uberon
def: "A bone that is part of the dorsal region of an animal." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "back bone" RELATED [MA:0000494]
synonym: "bone of back" RELATED [OBOL:automatic]
synonym: "dorsal region bone" RELATED [http://orcid.org/0000-0002-6601-2165]
xref: EMAPA:37248 {source="MA:th"}
xref: MA:0000494
is_a: UBERON:0001474 ! bone element
is_a: UBERON:0005174 ! dorsal region element
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0001137 ! dorsum
property_value: curator_notes "this class may be obsoleted. See: https://github.com/obophenotype/mouse-anatomy-ontology/issues/93" xsd:string
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0004253
name: skin muscle
namespace: uberon
alt_id: UBERON:0015797
def: "Any muscle organ that is part of a skin of body [Automatically generated definition]." [OBOL:automatic]
synonym: "integumental system muscle" EXACT [MA:0003139]
synonym: "muscle of integumental system" EXACT [EMAPA:18187]
synonym: "muscle organ of skin" EXACT [OBOL:automatic]
synonym: "skin muscle organ" EXACT [OBOL:automatic]
xref: EMAPA:18187
xref: EMAPA:35776
xref: MA:0002710
xref: MA:0003139
is_a: UBERON:0001630 ! muscle organ
intersection_of: UBERON:0001630 ! muscle organ
intersection_of: part_of UBERON:0002416 ! integumental system
relationship: located_in UBERON:0002097 ! skin of body
relationship: part_of UBERON:0002416 ! integumental system
property_value: editor_note "review as part of general integumentary system review - part of skin, or more generally, integumental system" xsd:string
property_value: UBPROP:0000012 "in MA, the only skin muscle is arrector pili. The only integumental muscle is panniculus carnosus. In EMAPA, the arrector pili only" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0004258
name: back blood vessel
namespace: uberon
def: "A blood vessel that is part of a back [Automatically generated definition]." [OBOL:automatic]
synonym: "blood vessel of back" EXACT [OBOL:automatic]
xref: EMAPA:37243 {source="MA:th"}
xref: MA:0000493
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0001137 ! dorsum
relationship: part_of UBERON:0001137 ! dorsum

[Term]
id: UBERON:0004265
name: outflow tract myocardium
namespace: uberon
def: "A myocardium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic]
synonym: "cardiac muscle of outflow tract" EXACT [OBOL:automatic]
synonym: "heart muscle of outflow tract" EXACT [OBOL:automatic]
synonym: "heart myocardium of outflow tract" EXACT [OBOL:automatic]
synonym: "muscle of heart of outflow tract" EXACT [OBOL:automatic]
synonym: "myocardium of outflow tract" EXACT [OBOL:automatic]
synonym: "outflow tract cardiac muscle" EXACT [OBOL:automatic]
synonym: "outflow tract heart muscle" EXACT [OBOL:automatic]
synonym: "outflow tract heart myocardium" EXACT [OBOL:automatic]
synonym: "outflow tract muscle of heart" EXACT [OBOL:automatic]
xref: EHDAA2:0001358
xref: EMAPA:35623
xref: MA:0000489
xref: VHOG:0000603
is_a: UBERON:0002349 ! myocardium
intersection_of: UBERON:0002349 ! myocardium
intersection_of: part_of UBERON:0004145 ! outflow tract
relationship: part_of UBERON:0004145 ! outflow tract
property_value: UBPROP:0000003 "(...) (theme) is how the vertebrate cardiovascular system differs from that of the presumptive evolutionary chordate ancestor. (...) At best we can tell there are two essential new ingredients: (1) vertebrates all have a continuous endothelial lining to the heart and vessels and (2) vertebrates have developed a second chamber in the heart, one designed for generating high systemic blood pressure.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000603", ontology="VHOG", source="PMID:9187138 Fishman MC, Chien KR, Fashioning the vertebrate heart: earliest embryonic decisions. Development (1997)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004267
name: back connective tissue
namespace: uberon
def: "A portion of connective tissue that is part of a back [Automatically generated definition]." [OBOL:automatic]
synonym: "mesenchyne of back" RELATED [OBOL:automatic]
xref: EMAPA:37256 {source="MA:th"}
xref: MA:0000495
is_a: UBERON:0002384 ! connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: part_of UBERON:0001137 ! dorsum
relationship: part_of UBERON:0001137 ! dorsum

[Term]
id: UBERON:0004271
name: outflow tract pericardium
namespace: uberon
def: "A pericardium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic]
synonym: "pericardium of outflow tract" EXACT [OBOL:automatic]
xref: EMAPA:37707 {source="MA:th"}
xref: MA:0000491
is_a: UBERON:0002407 ! pericardium
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0002407 ! pericardium
intersection_of: part_of UBERON:0004145 ! outflow tract
relationship: part_of UBERON:0004145 ! outflow tract

[Term]
id: UBERON:0004277
name: eye muscle
namespace: uberon
def: "A muscle that is part of the eye region." [OBOL:automatic]
subset: pheno_slim
xref: AAO:0000156
xref: EMAPA:35335
xref: MA:0000271
is_a: UBERON:0001630 ! muscle organ
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0001630 ! muscle organ
intersection_of: part_of UBERON:0000019 ! camera-type eye
relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye
relationship: part_of UBERON:0000019 {source="MA"} ! camera-type eye

[Term]
id: UBERON:0004288
name: skeleton
namespace: uberon
def: "Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body." [VSAO:0000026]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "set of all bones" EXACT []
synonym: "set of bones of body" EXACT []
xref: AEO:0000168
xref: EHDAA2:0001843
xref: EHDAA:5047
xref: EMAPA:17213
xref: FMA:23875
xref: GAID:177
xref: galen:Skeleton
xref: MA:0003006
xref: MAT:0000032
xref: MESH:D012863
xref: MIAA:0000032
xref: SCTID:361378004
xref: VSAO:0000026
xref: Wikipedia:Skeleton
xref: XAO:0004053
is_a: UBERON:0034925 ! anatomical collection
disjoint_from: UBERON:0004770 ! articular system
relationship: has_member UBERON:0004765 ! skeletal element
relationship: part_of UBERON:0001434 ! skeletal system
property_value: RO:0002171 UBERON:0000383
property_value: RO:0002175 NCBITaxon:9606
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/The-skeletal-system" xsd:anyURI
property_value: UBPROP:0000001 "Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000026", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070"}
property_value: UBPROP:0000007 "skeletal" xsd:string

[Term]
id: UBERON:0004290
name: dermomyotome
namespace: uberon
def: "The bilaminar epithelium formed from the myotome and dermatome." [AEO:0000214]
synonym: "dermamyotome" RELATED [VHOG:0000676]
synonym: "dermomyotomes" RELATED OMO:0003004 [VHOG:0000676]
xref: AAO:0010572
xref: AEO:0000214
xref: EHDAA2:0003259
xref: EMAPA:31109
xref: FMA:295654
xref: NCIT:C34140
xref: TAO:0001513
xref: UMLS:C1511786 {source="ncithesaurus:Dermomyotome"}
xref: VHOG:0000676
xref: ZFA:0001513
is_a: UBERON:0000486 {source="AEO"} ! multilaminar epithelium
is_a: UBERON:0016888 {source="AEO"} ! transitional anatomical structure
relationship: develops_from UBERON:0002329 {source="EHDAA2", source="ZFA"} ! somite
relationship: has_part CL:0000075 ! columnar/cuboidal epithelial cell
property_value: UBPROP:0000001 "all but the sclerotome of a mesodermal somite; the primordium of skeletal muscle and, perhaps, of the dermis." xsd:string {source="http://medical-dictionary.thefreedictionary.com/dermomyotome"}
property_value: UBPROP:0000001 "Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis. Within the dermomyotome there is also a medio-lateral difference. The central region makes dermis, the mesenchymal connective tissue of the back skin. The medial region (closest to neural tube) makes epaxial muscle, and the lateral region (furthest from neural tube) makes hypaxial muscle[http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A66768]." xsd:string {source="http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A66768"}
property_value: UBPROP:0000001 "Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001513", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Portion of somites that gives rise to dermis and muscles.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010572", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000003 "Thus, representatives of the agnathan vertebrates, chondrichthyans, and sarcopterygians all have a layer of undifferentiated cells external to the embryonic myotome. In the amniotes, this external cell layer is the dermomyotome. The simplest interpretation of the similar position, morphology, and lack of myosin labeling is that a dermomyotome epithelium is a shared, ancestral vertebrate characteristic.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000676", ontology="VHOG", source="DOI:10.1111/j.1525-142X.2006.05079.x Devoto SH, Stoiber W, Hammond CL, Steinbacher P, Haslett JR, Barresi MJF, Patterson SE, Adiarte EG and Hughes SM, Generality of vertebrate developmental patterns: evidence for a dermomyotome in fish. Evolution and Development (2006)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004291
name: heart rudiment
namespace: uberon
def: "A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." [GO:0003313]
synonym: "heart cone" EXACT [GO:0003313]
synonym: "rudimentary heart" EXACT [ZFA:0000115]
xref: TAO:0000115
xref: ZFA:0000115
is_a: UBERON:0012275 ! meso-epithelium
relationship: develops_from UBERON:0004139 ! cardiogenic plate
property_value: UBPROP:0000001 "The migrating myocardial precursors of the heart rudiment form a cone like structure between 19.5hpf and 22hpf, and eventually telescope out into the primitive heart tube at 24hpf. Stainier 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000115", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0004292
name: cardiac skeleton
namespace: uberon
def: "Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart." [GO:0003204, Wikipedia:Cardiac_skeleton]
synonym: "anulus fibrosus dexter cordis" RELATED OMO:0003011 [Wikipedia:Cardiac_skeleton]
synonym: "anulus fibrosus sinister cordis" RELATED OMO:0003011 [Wikipedia:Cardiac_skeleton]
synonym: "cardiac fibrous skeleton" EXACT [EMAPA:36645]
synonym: "fibrous skeleton of heart" EXACT []
synonym: "heart fibrous skeleton" EXACT [GO:0003204]
synonym: "skeleton of heart" EXACT [FMA:9496]
synonym: "trigona fibrosa" RELATED OMO:0003011 [Wikipedia:Cardiac_skeleton]
synonym: "trigonum fibrosum dextrum cordis" RELATED OMO:0003011 [Wikipedia:Cardiac_skeleton]
synonym: "trigonum fibrosum sinistrum cordis" RELATED OMO:0003011 [Wikipedia:Cardiac_skeleton]
xref: EMAPA:36645
xref: FMA:9496
xref: Wikipedia:Cardiac_skeleton
is_a: UBERON:0003837 ! thoracic segment connective tissue
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: adjacent_to UBERON:0002081 ! cardiac atrium
relationship: adjacent_to UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0000948 ! heart
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/50/Gray495.png" xsd:anyURI
property_value: UBPROP:0000009 "It is not a true skeleton, but it does provide structure and support for the heart, as well as isolating the atria from the ventricles. This allows the AV node and AV bundle to delay the wave of depolarisation such that the atria can contract and assist in ventricular filling before the ventricles themselves depolarise and contract (the AV bundle is the only part of the conduction system that passes from the atria to the ventricles in a normal heart). It also allows the valves (bicuspid, tricuspid, semilunar) to keep open by giving them structural support[WP]" xsd:string

[Term]
id: UBERON:0004297
name: respiratory system blood vessel smooth muscle
namespace: uberon
def: "A blood vessel smooth muscle that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "smooth muscle tissue of blood vessel of respiratory system" EXACT [OBOL:automatic]
xref: EMAPA:37573 {source="MA:th"}
xref: MA:0001806
is_a: UBERON:0004225 ! respiratory system smooth muscle
is_a: UBERON:0004237 ! blood vessel smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0003504 ! respiratory system blood vessel
relationship: part_of UBERON:0003504 ! respiratory system blood vessel

[Term]
id: UBERON:0004340
name: allantois
namespace: uberon
def: "A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals[VHOG]." [VHOG:0000738, Wikipedia:Allantois]
subset: pheno_slim
synonym: "allantoic bud" RELATED [EMAPA:16107]
xref: BTO:0000474
xref: EHDAA2:0001504
xref: EMAPA:16107
xref: EMAPA_RETIRED:16084
xref: MESH:D000482
xref: NCIT:C34101
xref: RETIRED_EHDAA2:0000114
xref: SCTID:308825007
xref: UMLS:C0002084 {source="ncithesaurus:Allantois"}
xref: VHOG:0000738
xref: Wikipedia:Allantois
is_a: UBERON:0005631 ! extraembryonic membrane
relationship: develops_from UBERON:0000162 {source="Hymans"} ! cloaca
relationship: has_developmental_contribution_from UBERON:0000925 {notes="hindgut diverticulum endoderm", source="ISBN:0073040584"} ! endoderm
relationship: has_developmental_contribution_from UBERON:0004872 {source="ISBN:0073040584"} ! splanchnic layer of lateral plate mesoderm
relationship: only_in_taxon NCBITaxon:32524 {source="Hymans"} ! Amniota
relationship: overlaps UBERON:0001008 {source="EHDAA2-modified"} ! renal system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/a/a5/Gray25.png" xsd:anyURI
property_value: UBPROP:0000001 "A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000738", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/allantois"}
property_value: UBPROP:0000003 "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000738", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.187", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "allantoic" xsd:string
property_value: UBPROP:0000011 "a diverticulum of the hindgut endoderm [ISBN:0073040584 (Vertebrates, Kardong)]" xsd:string
property_value: UBPROP:0000012 "part_of embryo in EHDAA2 - note differences in humans" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0004341
name: primitive streak
namespace: uberon
def: "The primitive streak is a structure that forms during the early stages of avian, reptilian and mammalian embryonic development[WP]. the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm[MP]." [MP:0002231, Wikipedia:Primitive_streak]
subset: early_development
subset: pheno_slim
synonym: "primitive streak - blastopore - germ ring" EXACT [VHOG:0001202]
xref: EHDAA2:0001525
xref: EHDAA:185
xref: EMAPA:16072
xref: FMA:293110
xref: MESH:D054240 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: NCIT:C28402
xref: SCTID:361438007
xref: UMLS:C0033153 {source="ncithesaurus:Primitive_Streak"}
xref: VHOG:0001202
xref: Wikipedia:Primitive_streak
is_a: UBERON:0000485 {source="EHDAA2"} ! simple columnar epithelium
is_a: UBERON:0005291 ! embryonic tissue
relationship: develops_from UBERON:0008780 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="ISBN:9780878932504"} ! inner cell mass derived epiblast
relationship: has_potential_to_develop_into UBERON:0000925 ! endoderm
relationship: has_potential_to_develop_into UBERON:0000926 ! mesoderm
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f4/Gray13.png" xsd:anyURI
property_value: RO:0002174 NCBITaxon:32443
property_value: UBPROP:0000003 "(...) the blastopore equivalent of chordates (germ ring in fish, marginal zone/blastopore lip in frog and node/primitive streak in chick and mouse) (...) (reference 1); Indeed, the primitive streak has been considered the homologue of the blastopore since the 1870s (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001202", ontology="VHOG", source="PMID:9609826 Wu LH, Lengyel JA, Role of caudal in hindgut specification and gastrulation suggests homology between Drosophila amnioproctodeal invagination and vertebrate blastopore. Development (1998), ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.139", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "VHOG includes a very broad grouping here based on http://www.ncbi.nlm.nih.gov/pubmed/9609826" xsd:string {external_ontology="VHOG"}

[Term]
id: UBERON:0004345
name: trophectoderm
namespace: uberon
def: "Outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition." [MP:0005028]
subset: early_development
subset: pheno_slim
xref: BTO:0001840
xref: EHDAA2:0002091
xref: EHDAA:56
xref: EMAPA:16046
xref: VHOG:0000979
is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium
is_a: UBERON:0005292 ! extraembryonic tissue
relationship: develops_from UBERON:0000085 {source="EHDAA2"} ! morula
relationship: has_part CL:1000274 ! trophectodermal cell
relationship: part_of UBERON:0005631 {source="EHDAA2"} ! extraembryonic membrane
property_value: editor_note "distinction between trophectoderm and trophoblast unclear/inconsistent in many sources" xsd:string
property_value: UBPROP:0000001 "The outer cellular layer of the mammalian blastocyst. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.750, see_Kardong_KV][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000979", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "(...) the trophoblast develops rapidly so that contact may be made with the maternal uterine tissues when conditions are appropriate. We have here an excellent example of an embryonic adaptation, the development of a structure never present in either adult or embryo of 'lower' vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000979", ontology="VHOG", source="ISBN:978-0721676685 Romer AS, Parsons TS, Vertebrate body (1977) p.105-106", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "trophectodermal" xsd:string
property_value: UBPROP:0000012 "BTO has this has part of the trophoblast" xsd:string {external_ontology="BTO"}

[Term]
id: UBERON:0004348
name: optic eminence
namespace: uberon
def: "The embryonic structure that gives rise to the corneal ectoderm." [MP:0006305]
subset: pheno_slim
xref: EHDAA:938
xref: EMAPA:16322
xref: RETIRED_EHDAA2:0001308
xref: VHOG:0001296
is_a: UBERON:0006598 ! presumptive structure
relationship: has_potential_to_develop_into UBERON:0000964 ! cornea

[Term]
id: UBERON:0004356
name: apical ectodermal ridge
namespace: uberon
def: "Multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]." [MP:0001676, Wikipedia:Apical_ectodermal_ridge]
subset: pheno_slim
synonym: "AER" RELATED [MP:0001676]
synonym: "apical epidermal ridge" EXACT [XAO:0004121]
synonym: "crista ectodermalis apicalis" RELATED OMO:0003011 [Wikipedia:Apical_ectodermal_ridge]
xref: AAO:0010760
xref: EMAPA:32744
xref: NCIT:C34109
xref: TAO:0002146
xref: UMLS:C1516037 {source="ncithesaurus:Apical_Ectodermal_Ridge"}
xref: Wikipedia:Apical_ectodermal_ridge
xref: XAO:0004121
xref: ZFA:0001702
is_a: UBERON:0002050 ! embryonic structure
relationship: capable_of GO:0010464 ! regulation of mesenchymal cell proliferation
relationship: capable_of GO:0061037 ! negative regulation of cartilage development
relationship: developmentally_induced_by UBERON:0003104 ! mesenchyme
relationship: part_of UBERON:0000924 ! ectoderm
relationship: part_of UBERON:0004357 ! paired limb/fin bud
relationship: produces PR:000007499 ! fibroblast growth factor 8
property_value: curator_notes "note that media, dorsal fins etc have AERs." xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/56/Limbbuddiagram.jpg" xsd:anyURI
property_value: UBPROP:0000001 "Distal ectodermal thickening which forms along the anterior-posterior limb axis. Signaling from this region influences proximal-distal patterning of the limb. Structure is missing in some lineages (salamanders, Eleutherodactylus coqui) however morphologically their indistinct distal ectoderm may still be involved in signaling.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010760", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "Proliferative region that is part of the developing fin fold or fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002146", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000002 "relationship loss: subclass proliferative region (TAO:0000098)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002146", ontology="TAO"}
property_value: UBPROP:0000008 "The AER of tetrapods regresses after specification of skeletal progenitors, the AER of teleosts form an elongating fin fold" xsd:string {source="PMID:20574421"}
property_value: UBPROP:0000009 "maintaining mesenchyme in plastic proliferating state; maintaining expression of A-P axis genes; interacting with D-V proteins. Genes: AER induced by Fgf10 in mesenchyme. AER secretes Fgf8, which stimulates mitosis in the mesenchyme causing Fgf10 production - positive feedback loop" xsd:string

[Term]
id: UBERON:0004357
name: paired limb/fin bud
namespace: uberon
def: "An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]." [https://orcid.org/0000-0002-6601-2165, ISBN:9780878932504, MP:0005650]
comment: Genes: In limb buds of chick and mouse, Shh expression is activated as soon as there is a morphological bud, whereas in S. canicula fin buds, consistent with reported data in other cartilaginous fishes, Shh is transcribed late in fin development[PMID:17187056]
subset: homology_grouping
synonym: "limb - fin bud" EXACT [VHOG:0001258]
synonym: "paired appendage bud" EXACT []
synonym: "paired limb/fin bud" EXACT [VHOG:0001258]
xref: VHOG:0001258
is_a: UBERON:0003102 ! surface structure
is_a: UBERON:0006598 ! presumptive structure
relationship: has_developmental_contribution_from UBERON:0005732 ! paired limb/fin field
relationship: has_part UBERON:0004356 ! apical ectodermal ridge
relationship: has_potential_to_develop_into UBERON:0004708 ! paired limb/fin
property_value: UBPROP:0000003 "The tetrapod limb is derived from a posterior part of the fin endoskeleton of elasmobranchs and basal bony fish, the so-called metapterygium, a series of endoskeletal elements that is the first to form in the developing paired fins. (...) In addition, there is an independent endoskeletal element called the protopterygium that develops anterior to the metapterygium in many basal fishes (e.g., the bichir and sturgeon). Teleosts have lost the metapterygium whereas the sarcopterygians, on the other hand, have lost the protopterygium. Sarcopterygians thus develop all their endoskeletal structures from the metapterygium and consequently the tetrapod limb skeleton is derived from the metapterygium.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001258", ontology="VHOG", source="DOI:10.1002/jez.1100 Wagner GP, Chiu C, The tetrapod limb: A hypothesis on its origin. J Exp Zool (Mol Dev Evol) (2001)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004362
name: pharyngeal arch 1
namespace: uberon
def: "The first of the series of pharyngeal arches that develop into jaw bones or their homologs, and their associated nerves and arteries." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "1st arch" RELATED [EHDAA2:0000006]
synonym: "1st pharyngeal arch" EXACT []
synonym: "1st visceral arch" RELATED [VHOG:0000296]
synonym: "arcus pharyngeus primus" RELATED OMO:0003011 [Wikipedia:First_pharyngeal_arch]
synonym: "branchial arch 1" EXACT SENSU []
synonym: "first branchial arch" EXACT SENSU []
synonym: "first pharyngeal arch" EXACT []
synonym: "first visceral arch" EXACT SENSU []
synonym: "mandibular arch" EXACT []
synonym: "visceral arch 1" EXACT SENSU []
xref: AAO:0010364
xref: CALOHA:TS-2089
xref: EHDAA2:0000006
xref: EHDAA:573
xref: EMAPA:16118
xref: FMA:293019
xref: MFMO:0000095
xref: NCIT:C34175
xref: SCTID:308767008
xref: TAO:0001595
xref: UMLS:C1517197 {source="ncithesaurus:First_Pharyngeal_Arch"}
xref: VHOG:0000296
xref: Wikipedia:First_pharyngeal_arch
xref: XAO:0000097
xref: ZFA:0001612
is_a: UBERON:0002539 ! pharyngeal arch
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray48.png" xsd:anyURI
property_value: UBPROP:0000001 "the first arch which contributes to development of mastication muscles, maxilla, mandible, incus, malleus, Meckel's cartilage, trigeminal nerve, and maxillary artery" xsd:string {source="MP:0006337,MGI:smb"}
property_value: UBPROP:0000001 "The first of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010364", ontology="AAO", source="XAO:EJS"}
property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000296", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M and Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000103 "1" xsd:nonNegativeInteger

[Term]
id: UBERON:0004363
name: pharyngeal arch artery
namespace: uberon
alt_id: UBERON:0004342
def: "One of a series of paired embryological vascular structures formed within a pharyngeal arch; in the adult, some of these vessels give rise to the great vessels[MP]." [MP:0002672]
subset: efo_slim
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "a. arcuum pharyngeorum" RELATED OMO:0003011 [Wikipedia:Aortic_arches]
synonym: "aortic arch" EXACT [ZFA:0005004]
synonym: "aortic arch artery" RELATED [EMAPA:16684]
synonym: "aortic arches" EXACT OMO:0003004 [ZFA:0005004]
synonym: "arteriae arcuum pharyngeorum" RELATED OMO:0003011 [Wikipedia:Aortic_arches]
synonym: "branchial aortic arches" EXACT OMO:0003004 [ZFIN:ZDB-PUB-080512-6]
synonym: "branchial aortic arches" RELATED OMO:0003004 [ZFA:0005004, ZFIN:ZDB-PUB-080512-6]
synonym: "branchial arch artery" EXACT [EMAPA:16684]
synonym: "embryonic aortic arch artery" EXACT [EMAPA:16684, MP:0002672]
synonym: "PAA" EXACT OMO:0003000 [MP:0002672]
synonym: "pharyngeal arch arteries" RELATED OMO:0003004 []
synonym: "pharyngeal arch artery" EXACT [MP:0002672]
synonym: "pharyngeal arch artery" RELATED [VHOG:0000122]
xref: AAO:0010414
xref: EFO:0003695
xref: EHDAA2:0000186
xref: EHDAA:398
xref: EHDAA:7327
xref: EMAPA:16684
xref: NCIT:C32123
xref: TAO:0005004
xref: UMLS:C0003489 {source="ncithesaurus:Aortic_Arch"}
xref: VHOG:0000122
xref: Wikipedia:Aortic_arches
xref: XAO:0000341
xref: ZFA:0005004
is_a: UBERON:0003469 ! respiratory system artery
is_a: UBERON:0003496 ! head blood vessel
is_a: UBERON:0006598 ! presumptive structure
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
relationship: contributes_to_morphology_of UBERON:0002539 ! pharyngeal arch
relationship: has_potential_to_develop_into UBERON:0001637 ! artery
relationship: part_of UBERON:0002539 ! pharyngeal arch
relationship: part_of UBERON:0007303 {source="ZFA"} ! pharyngeal vasculature
property_value: curator_notes "Do not confuse with arch of aorta." xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/84/Gray473.png" xsd:anyURI
property_value: editor_note "add specific artery derivatives" xsd:string
property_value: UBPROP:0000001 "Paired vessels arching from the ventral to the dorsal aorta through the pharyngeal arches. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000122", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/aortic+arches"}
property_value: UBPROP:0000003 "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000122", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "Number varies - Lampreys have 8, hagfishes 15; only up to 6 appear in embryonic development in most gnathostome fishes and all tetrapods" xsd:string
property_value: UBPROP:0000011 "The third, fourth, and sixth arches, along with the seventh intersegmental arteries and the left dorsal aorta, are the primary contributors to the normal aortic arch and its major thoracic branches" xsd:string

[Term]
id: UBERON:0004364
name: ectoplacental cone
namespace: uberon
def: "Thickened trophoblast of the blastocyst in rodents that becomes the fetal portion of the placenta." [MP:0001717, PMID:19829370]
subset: pheno_slim
synonym: "epamniotic cone" EXACT []
synonym: "placenta - ectoplacental cone" EXACT []
xref: BTO:0001715
xref: EMAPA:16059
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0000088 ! trophoblast
property_value: UBPROP:0000011 "derivative of the early postimplantation trophoblast, which probably gives rise to the spongiotrophoblast." xsd:string {source="PMID:19829370"}

[Term]
id: UBERON:0004365
name: vitelline blood vessel
namespace: uberon
def: "Blood vessel that is connected to the yolk sac." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
xref: EMAPA:36494
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: connected_to UBERON:0001040 ! yolk sac
relationship: connected_to UBERON:0001040 ! yolk sac
relationship: part_of UBERON:0004374 ! vitelline vasculature

[Term]
id: UBERON:0004367
name: Descemet's membrane
namespace: uberon
def: "A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]." [https://github.com/obophenotype/uberon/issues/15, MP:0004285]
comment: The strong, resistant, thin, noncellular fourth layer of the cornea, located between the endothelium (from which it is secreted) and the stroma. (Cline et al., Dictionary of Visual Science, 4th ed)
subset: pheno_slim
subset: vertebrate_core
synonym: "Descemet membrane" EXACT []
synonym: "Descemet's posterior elastic lamina" EXACT [FMA:58309]
synonym: "lamina limitans posterior" EXACT [FMA:58309]
synonym: "lamina limitans posterior corneae" EXACT OMO:0003011 [FMA:58309, FMA:TA]
synonym: "posterior limiting lamina" EXACT [MA:0001246]
synonym: "posterior limiting lamina of cornea" EXACT [FMA:58309]
synonym: "posterior limiting membrane" EXACT [ZFA:0001686]
xref: EMAPA:18804
xref: FMA:58309
xref: GAID:894
xref: MA:0001246
xref: MESH:D003886
xref: NCIT:C32454
xref: SCTID:281076002
xref: TAO:0002157
xref: UMLS:C0011665 {source="ncithesaurus:Descemet_s_Membrane"}
xref: Wikipedia:Descemet%27s_membrane
xref: ZFA:0001686
is_a: UBERON:0005769 ! basement membrane of epithelium
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0005769 ! basement membrane of epithelium
intersection_of: adjacent_to UBERON:0001777 ! substantia propria of cornea
intersection_of: adjacent_to UBERON:0001985 ! corneal endothelium
intersection_of: part_of UBERON:0000964 ! cornea
disjoint_from: UBERON:0004370 {source="lexical"} ! anterior limiting lamina of cornea
relationship: adjacent_to UBERON:0001777 ! substantia propria of cornea
relationship: adjacent_to UBERON:0001985 ! corneal endothelium
relationship: has_quality PATO:0000964 ! transparent
relationship: part_of UBERON:0000964 ! cornea
relationship: produced_by UBERON:0001985 {source="Cline et al"} ! corneal endothelium
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/gkoutos
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/15" xsd:anyURI
property_value: UBPROP:0000001 "Acellular anatomical structure composed of collagen, Descemet's membrane is secreted as a basement membrane of the corneal endothelium. Located between the stroma and the corneal endothelium, it is approximately 0.15 micrometer thick at 6 months post-fertilization.[ZFIN]" xsd:string {date_retrieved="2016-05-01", external_class="TAO:0002157", ontology="ZFIN", source="ZFIN:ZDB-PUB-061010-3", source="https://orcid.org/0000-0001-9114-8737"}

[Term]
id: UBERON:0004370
name: anterior limiting lamina of cornea
namespace: uberon
def: "A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane." [ncithesaurus:Bowman_s_Membrane]
subset: pheno_slim
subset: vertebrate_core
synonym: "anterior elastic lamina" EXACT [ZFA:0001684]
synonym: "anterior limiting lamina" EXACT [MA:0001240]
synonym: "anterior limiting lamina of cornea" EXACT [FMA:58273]
synonym: "anterior limiting membrane" RELATED [ZFA:0001684]
synonym: "Bowman's anterior elastic lamina" EXACT [FMA:58273]
synonym: "Bowman's layer" EXACT [FMA:58273]
synonym: "Bowman's membrane" EXACT [FMA:58273]
synonym: "lamina limitans anterior (cornea)" EXACT [FMA:58273]
synonym: "lamina limitans anterior corneae" EXACT OMO:0003011 [FMA:58273, FMA:TA]
synonym: "Reichert's membrane" RELATED OMO:0003002 [http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957]
xref: FMA:58273
xref: MA:0001240
xref: NCIT:C32226
xref: SCTID:281075003
xref: TAO:0002155
xref: UMLS:C0229127 {source="ncithesaurus:Bowman_s_Membrane"}
xref: Wikipedia:Bowman%27s_membrane
xref: ZFA:0001684
is_a: UBERON:0005769 ! basement membrane of epithelium
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0005769 ! basement membrane of epithelium
intersection_of: attaches_to UBERON:0001772 ! corneal epithelium
intersection_of: part_of UBERON:0000964 ! cornea
relationship: attaches_to UBERON:0001772 ! corneal epithelium
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0000964 ! cornea
property_value: UBPROP:0000001 "Acellular anatomical structure that is the zone of collagen fibers adjacent the basement membrane of the corneal epithelium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002155", ontology="TAO", source="ZFIN:ZDB-PUB-061010-3"}
property_value: UBPROP:0000008 "Compared to terrestial animals, the cornea of zebrafish is relatively flat. It consists of nonpigmented, stratified squamous nonkeratinizing epithelial cells, attached to a thick basement membrane that is considered to be analogous to the Bowman's membrane in mammals" xsd:string

[Term]
id: UBERON:0004374
name: vitelline vasculature
namespace: uberon
def: "Vascular network that is connected to the yolk sac." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "omphalomesenteric system" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "vitelline bloos vessel system" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "vitelline system" RELATED [https://orcid.org/0000-0002-6601-2165]
xref: Wikipedia:Vitelline_circulation
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: connected_to UBERON:0001040 ! yolk sac
relationship: connected_to UBERON:0001040 ! yolk sac
relationship: part_of RO:0002577 ! system

[Term]
id: UBERON:0004375
name: bone of free limb or fin
namespace: uberon
def: "A bone that is part of an appendage [Automatically generated definition]." [OBOL:automatic]
subset: homology_grouping
synonym: "appendage bone" EXACT []
synonym: "bone of appendage" EXACT []
synonym: "bone of free segment of appendicular skeleton" EXACT []
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0010740 ! bone of appendage girdle complex
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0004708 ! paired limb/fin
relationship: part_of UBERON:0011582 ! paired limb/fin skeleton

[Term]
id: UBERON:0004451
name: trunk or cervical vertebra
namespace: uberon
def: "A vertebra in the trunk or cervical region. Includes all cervical, thoracic and lumbar vertebrae, but excludes caudal vertebra." [UBERONREF:0000006]
subset: pheno_slim
synonym: "presacral vertebra" RELATED [MA:0002869]
xref: EMAPA:37722 {source="MA:th"}
xref: MA:0002869
xref: XAO:0003077
is_a: UBERON:0002412 ! vertebra
intersection_of: UBERON:0002412 ! vertebra
intersection_of: anterior_to UBERON:0001095 ! caudal vertebra
union_of: UBERON:0002413 ! cervical vertebra
union_of: UBERON:0011677 ! trunk vertebra
relationship: anterior_to UBERON:0001095 ! caudal vertebra
property_value: UBPROP:0000008 "In humans, there are 24 presacral vertebrae (7 cervical, 12 thoracic, and 5 lumbar)" xsd:string
property_value: UBPROP:0000012 "it's not clear if the XAO class belongs here or below" xsd:string {external_ontology="XAO"}

[Term]
id: UBERON:0004455
name: neurula embryo
namespace: uberon
alt_id: UBERON:0007013
def: "An embryo at the neurula stage." [http://orcid.org/0000-0002-6601-2165]
synonym: "neurula" EXACT [BTO:0001766]
xref: BILA:0000061
xref: BTO:0001766
xref: NCIT:C34229
xref: UMLS:C1518306 {source="ncithesaurus:Neurula"}
is_a: UBERON:0000922 ! embryo
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: existence_starts_and_ends_during UBERON:0000110 ! neurula stage
relationship: develops_from UBERON:0004734 ! gastrula
relationship: existence_starts_and_ends_during UBERON:0000110 ! neurula stage

[Term]
id: UBERON:0004456
name: entire sense organ system
namespace: uberon
def: "Sum of all sensory systems in an organism." [http://orcid.org/0000-0002-6601-2165]
subset: uberon_slim
synonym: "sense organ system" EXACT [FMA:78499]
xref: FMA:78499
is_a: UBERON:0000467 ! anatomical system
disjoint_from: UBERON:8450002 ! excretory system
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: overlaps UBERON:0001016 ! nervous system
property_value: UBPROP:0000012 "note the distinct between entire sensory system and individual system. this reconciles is_a and part_of distinctions between ssAOs" xsd:string

[Term]
id: UBERON:0004461
name: skeletal musculature of head
namespace: uberon
def: "Any collection of skeletal muscles that is part of a head [Automatically generated definition]." [OBOL:automatic]
comment: This class is restricted to skeletal muscles that attach to the cranial skeleton. This seems to be consistent with FMA and EMAPA usage. Note that by definition this excludes invertebrate head musculature. It corresponds to the individual muscle organ term UBERON:0002376
subset: non_informative
synonym: "head musculature" EXACT [FMA:71287]
synonym: "muscle group of head" EXACT [FMA:71287]
synonym: "muscles of head" EXACT [FMA:71287]
synonym: "musculi capitis" EXACT OMO:0003011 [FMA:71287, FMA:TA]
synonym: "set of muscles of head" EXACT [FMA:71287]
xref: EMAPA:18171
xref: FMA:71287
is_a: UBERON:0008229 ! craniocervical region musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: attaches_to UBERON:0003129 ! skull
intersection_of: part_of UBERON:0000033 ! head
relationship: attaches_to UBERON:0003129 ! skull
relationship: develops_from UBERON:0005253 ! head mesenchyme
relationship: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0013700 ! axial musculature
property_value: seeAlso "https://github.com/obophenotype/mouse-anatomy-ontology/issues/4" xsd:anyURI
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/1405" xsd:anyURI

[Term]
id: UBERON:0004464
name: musculature of thorax
namespace: uberon
def: "Any collection of muscles that is part of a thorax [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "muscle group of thorax" EXACT [FMA:71293]
synonym: "muscles of thorax" EXACT [FMA:71293]
synonym: "musculi thoracis" EXACT OMO:0003011 [FMA:71293, FMA:TA]
synonym: "set of muscles of thorax" EXACT [FMA:71293]
synonym: "thoracic musculature" EXACT [FMA:71293]
xref: BTO:0000508
xref: EMAPA:37260 {source="MA:th"}
xref: FMA:71293
is_a: UBERON:0004479 ! musculature of trunk
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0000915 ! thoracic segment of trunk
property_value: UBPROP:0000012 "BTO and FMA do not mean precisely the same thing here. BTO thorax muscle is a pectoral muscle or diaphragm" xsd:string {external_ontology="BTO"}

[Term]
id: UBERON:0004465
name: musculature of neck
namespace: uberon
def: "Any collection of muscles that is part of a neck [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "cervical muscles" EXACT [AAO:0000091]
synonym: "muscle group of neck" EXACT [FMA:71290]
synonym: "muscles of neck" EXACT [FMA:71290]
synonym: "musculi cervicis" EXACT OMO:0003011 [FMA:71290, FMA:TA]
synonym: "musculi colli" EXACT OMO:0003011 [FMA:71290, FMA:TA]
synonym: "neck musculature" EXACT [FMA:71290]
synonym: "set of muscles of neck" EXACT [FMA:71290]
xref: AAO:0000091
xref: EMAPA:36050
xref: FMA:71290
xref: MESH:D009334
is_a: UBERON:0001015 ! musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0000974 ! neck
relationship: part_of UBERON:0000974 ! neck

[Term]
id: UBERON:0004468
name: set of muscles of vertebral column
namespace: uberon
synonym: "muscle group of vertebral column" EXACT [FMA:33061]
xref: FMA:33061
is_a: UBERON:0001015 ! musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: attaches_to UBERON:0001130 ! vertebral column
relationship: attaches_to UBERON:0001130 ! vertebral column
relationship: part_of RO:0002577 ! system

[Term]
id: UBERON:0004469
name: musculature of back
namespace: uberon
def: "Any collection of muscles that is part of a back [Automatically generated definition]." [OBOL:automatic]
synonym: "muscle group of back" EXACT [FMA:71291]
synonym: "muscles of back" EXACT [FMA:71291]
synonym: "musculi dorsi" EXACT OMO:0003011 [FMA:71291, FMA:TA]
synonym: "set of muscles of back" EXACT [FMA:71291]
xref: FMA:71291
is_a: UBERON:0001015 ! musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0001137 ! dorsum
relationship: part_of UBERON:0001137 ! dorsum

[Term]
id: UBERON:0004470
name: musculature of pelvic girdle
namespace: uberon
alt_id: UBERON:0004485
alt_id: UBERON:0005633
def: "Any collection of muscles that is part of a pelvic girdle [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "muscle group of pelvic girdle" EXACT [FMA:50205]
synonym: "muscle group of pelvis" EXACT [FMA:50248]
synonym: "muscular system of pelvis" RELATED [FMA:50248]
synonym: "pelvic girdle muscle system" EXACT [EHDAA2:0001429]
synonym: "pelvic girdle muscles" EXACT [AAO:0000427]
synonym: "pelvic girdle musculature" EXACT [FMA:50205]
synonym: "set of muscles of pelvic girdle" EXACT [FMA:50205]
synonym: "set of muscles of pelvis" RELATED [FMA:50248]
xref: AAO:0000427
xref: EHDAA2:0001429
xref: EMAPA:18184
xref: FMA:50205
xref: FMA:50248
is_a: UBERON:0004479 ! musculature of trunk
is_a: UBERON:0014792 ! musculature of pelvic complex
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0001271 ! pelvic girdle region
relationship: part_of UBERON:0001271 ! pelvic girdle region
property_value: UBPROP:0000012 "we merge two FMA classes here" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0004471
name: musculature of pectoral girdle
namespace: uberon
def: "A subdivision of the musculature of the body in the pectoral girdle region. Includes pectoral and shoulder muscles." [https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "muscle group of pectoral girdle" EXACT [FMA:33519]
synonym: "pectoral girdle muscles" EXACT [AAO:0000423]
synonym: "pectoral girdle musculature" EXACT [FMA:33519]
synonym: "set of muscles of pectoral girdle" EXACT [FMA:33519]
xref: AAO:0000423
xref: EMAPA:37857 {source="MA:th"}
xref: FMA:33519
is_a: UBERON:0014793 ! musculature of pectoral complex
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0001421 ! pectoral girdle region
relationship: part_of UBERON:0001421 ! pectoral girdle region

[Term]
id: UBERON:0004473
name: musculature of face
namespace: uberon
def: "Any collection of muscles that is part of a face." [OBOL:automatic]
subset: pheno_slim
synonym: "entire facial musculature" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "facial muscles" EXACT [FMA:71288]
synonym: "muscle group of face" EXACT [FMA:71288]
synonym: "musculi faciei" EXACT OMO:0003011 [FMA:71288, FMA:TA]
synonym: "set of facial muscles" RELATED [FMA:71288]
synonym: "set of muscles of face" RELATED [FMA:71288]
xref: FMA:71288
is_a: UBERON:0008229 ! craniocervical region musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0001456 ! face
relationship: part_of UBERON:0001456 ! face
property_value: editor_note "originally created to reflect the distinction drawn in FMA between a facial muscle and the entire musculature of the face. However, naming both does not serve any particular purpose" xsd:string

[Term]
id: UBERON:0004479
name: musculature of trunk
namespace: uberon
def: "Any collection of muscles that is part of a trunk [Automatically generated definition]." [OBOL:automatic]
subset: efo_slim
subset: pheno_slim
synonym: "muscle group of trunk" EXACT [FMA:50187]
synonym: "muscular system of trunk" RELATED [FMA:50187]
synonym: "set of muscles of trunk" EXACT [FMA:50187]
xref: AAO:0011572
xref: EFO:0003531
xref: FMA:50187
is_a: UBERON:0001015 ! musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk
property_value: editor_note "currently defined by location rather than attachment" xsd:string

[Term]
id: UBERON:0004490
name: cardiac muscle tissue of atrium
namespace: uberon
def: "A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition]." [OBOL:automatic]
synonym: "atrial cardiac muscle tissue" EXACT [GO:0055009]
synonym: "atrial heart muscle" EXACT [GO:0055009]
synonym: "atrial myocardium" RELATED [GO:0055009, GOC:mtg_heart]
synonym: "cardiac atrium muscle" EXACT [GO:0055009]
xref: FMA:7283
is_a: UBERON:0004493 ! cardiac muscle tissue of myocardium
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002081 ! cardiac atrium
relationship: part_of UBERON:0002302 ! myocardium of atrium
property_value: UBPROP:0000012 "in GO, this is equivalent to the atrial myocardium, but FMA distinguishes these two. Consider merging." xsd:string {external_ontology="GO"}

[Term]
id: UBERON:0004491
name: cardiac muscle tissue of interatrial septum
namespace: uberon
def: "A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition]." [OBOL:automatic]
synonym: "interatrial septum cardiac muscle tissue" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "interatrial septum heart muscle" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "interatrial septum muscle" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "interatrial septum myocardium" EXACT [http://orcid.org/0000-0002-6601-2165]
xref: FMA:84083
is_a: UBERON:0004492 ! cardiac muscle tissue of cardiac septum
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002085 ! interatrial septum
relationship: part_of UBERON:0002085 ! interatrial septum

[Term]
id: UBERON:0004492
name: cardiac muscle tissue of cardiac septum
namespace: uberon
def: "A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition]." [OBOL:automatic]
synonym: "cardiac septum cardiac muscle tissue" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "cardiac septum heart muscle" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "cardiac septum muscle" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "cardiac septum myocardium" EXACT [http://orcid.org/0000-0002-6601-2165]
xref: FMA:226279
is_a: UBERON:0001133 ! cardiac muscle tissue
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002099 ! cardiac septum
relationship: part_of UBERON:0002099 ! cardiac septum

[Term]
id: UBERON:0004493
name: cardiac muscle tissue of myocardium
namespace: uberon
def: "A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
xref: EMAPA:32688
xref: FMA:261726
xref: MA:0002441
is_a: UBERON:0001133 ! cardiac muscle tissue
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002349 ! myocardium
relationship: part_of UBERON:0002349 {source="MA"} ! myocardium
property_value: editor_note "Note placement of MA class based on parthood relationship" xsd:string

[Term]
id: UBERON:0004495
name: skeletal muscle tissue of diaphragm
namespace: uberon
def: "A portion of skeletal muscle tissue that is part of a diaphragm [Automatically generated definition]." [OBOL:automatic]
xref: FMA:261898
is_a: UBERON:0003898 ! skeletal muscle tissue of trunk
is_a: UBERON:0004830 ! respiratory system skeletal muscle
intersection_of: UBERON:0001134 ! skeletal muscle tissue
intersection_of: part_of UBERON:0001103 ! diaphragm
relationship: part_of UBERON:0001103 ! diaphragm

[Term]
id: UBERON:0004518
name: muscle of vertebral column
namespace: uberon
def: "A muscle that is attached to a vertebra of the vertebral column." [https://orcid.org/0000-0002-6601-2165]
synonym: "vertebral column muscle" EXACT [FMA:22594]
xref: FMA:22594
is_a: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: attaches_to UBERON:0002412 ! vertebra
relationship: attaches_to UBERON:0002412 ! vertebra

[Term]
id: UBERON:0004521
name: vasculature of muscle organ
namespace: uberon
def: "A vasculature that is part of a muscle organ [Automatically generated definition]." [OBOL:automatic]
synonym: "muscular organ vasculature" EXACT [FMA:87123]
xref: FMA:87123
is_a: UBERON:0006876 ! vasculature of organ
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0001630 ! muscle organ
relationship: part_of UBERON:0001630 ! muscle organ

[Term]
id: UBERON:0004522
name: vasculature of musculoskeletal system
namespace: uberon
def: "A vasculature that is part of a musculoskeletal system [Automatically generated definition]." [OBOL:automatic]
xref: FMA:239607
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0002204 ! musculoskeletal system
relationship: part_of UBERON:0002204 ! musculoskeletal system

[Term]
id: UBERON:0004525
name: cardiac muscle tissue of trabecula carnea of right ventricle
namespace: uberon
def: "A portion of trabecula carnea cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]." [OBOL:automatic]
xref: FMA:84429
is_a: UBERON:0003381 ! cardiac muscle of right ventricle
is_a: UBERON:0003452 ! trabecula carnea cardiac muscle tissue
intersection_of: UBERON:0003452 ! trabecula carnea cardiac muscle tissue
intersection_of: part_of UBERON:0002080 ! heart right ventricle
relationship: part_of UBERON:0006570 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! trabecula carnea of right ventricle

[Term]
id: UBERON:0004526
name: cardiac muscle tissue of trabecula carnea of left ventricle
namespace: uberon
def: "A portion of trabecula carnea cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]." [OBOL:automatic]
xref: FMA:84430
is_a: UBERON:0003382 ! cardiac muscle of left ventricle
is_a: UBERON:0003452 ! trabecula carnea cardiac muscle tissue
intersection_of: UBERON:0003452 ! trabecula carnea cardiac muscle tissue
intersection_of: part_of UBERON:0002084 ! heart left ventricle
relationship: part_of UBERON:0006571 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! trabecula carnea of left ventricle

[Term]
id: UBERON:0004533
name: left testis
namespace: uberon
def: "A testis that is in the left side of the genitalia [Automatically generated definition]." [OBOL:automatic]
synonym: "left testicle" EXACT [MA:0001746]
xref: EMAPA:37370 {source="MA:th"}
xref: FMA:7212
xref: MA:0001746
xref: NCIT:C49323
xref: SCTID:367720001
xref: UMLS:C0227998 {source="ncithesaurus:Left_Testis"}
is_a: UBERON:0000473 ! testis
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0000473 ! testis
intersection_of: in_left_side_of UBERON:0000990 ! reproductive system
relationship: in_left_side_of UBERON:0000990 ! reproductive system
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0004534
name: right testis
namespace: uberon
def: "A testis that is in the right side of the genitalia [Automatically generated definition]." [OBOL:automatic]
synonym: "right testicle" EXACT [MA:0001747]
xref: EMAPA:37371 {source="MA:th"}
xref: FMA:7211
xref: MA:0001747
xref: NCIT:C49326
xref: SCTID:367719007
xref: UMLS:C0227997 {source="ncithesaurus:Right_Testis"}
is_a: UBERON:0000473 ! testis
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0000473 ! testis
intersection_of: in_right_side_of UBERON:0000990 ! reproductive system
relationship: in_right_side_of UBERON:0000990 ! reproductive system
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0004535
name: cardiovascular system
namespace: uberon
def: "Anatomical system that has as its parts the heart and blood vessels." [BTO:0000088]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
subset: vertebrate_core
synonym: "CV system" RELATED [BTO:0000088]
synonym: "Herz und Gefaesssystem" RELATED [BTO:0000088]
xref: AAO:0011001
xref: BILA:0000016
xref: BTO:0000088
xref: CALOHA:TS-1297
xref: EFO:0000791
xref: EHDAA2:0000216
xref: EHDAA:394
xref: EMAPA:16104
xref: EMAPA:16370
xref: EV:0100017
xref: FMA:7161
xref: GAID:467
xref: MA:0000010
xref: MAT:0000016
xref: MESH:D002319
xref: MIAA:0000016
xref: NCIT:C12686
xref: SCTID:278198007
xref: TAO:0000010
xref: UMLS:C0007226 {source="ncithesaurus:Cardiovascular_System"}
xref: VHOG:0000302
xref: WikipediaCategory:Cardiovascular_system
xref: XAO:0000100
xref: XAO:0001010
xref: ZFA:0000010
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000467 ! anatomical system
intersection_of: UBERON:0000467 ! anatomical system
intersection_of: has_part UBERON:0000948 ! heart
intersection_of: has_part UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0001009 ! circulatory system
relationship: has_part UBERON:0000948 ! heart
relationship: has_part UBERON:0001981 ! blood vessel
relationship: part_of UBERON:0001009 ! circulatory system
property_value: curator_notes "we treat cardiovascular as part of circulatory system, with the latter including other kinds of circulation, including lymph." xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "The vessels of the cardiovascular system are as varied as the diverse organs they supply. However, these variations are based on modifications of a fundamental plan of organization common to vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000302", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.451", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004537
name: blood vasculature
namespace: uberon
def: "A vascular network consisting of blood vessels." [https://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
synonym: "blood system" RELATED []
synonym: "blood vascular network" EXACT []
synonym: "blood vessel system" RELATED []
synonym: "blood vessels" RELATED [TAO:0001079]
synonym: "set of blood vessels" EXACT []
xref: TAO:0001079
xref: ZFA:0001079
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: composed_primarily_of UBERON:0001981 ! blood vessel
relationship: composed_primarily_of UBERON:0001981 ! blood vessel
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004538
name: left kidney
namespace: uberon
def: "A kidney that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
xref: EMAPA:36589
xref: FMA:7205
xref: MA:0001655
xref: NCIT:C34006
xref: SCTID:362209008
xref: UMLS:C0227614 {source="ncithesaurus:Left_Kidney"}
is_a: UBERON:0002113 ! kidney
intersection_of: UBERON:0002113 ! kidney
intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Kidney_Left.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Kidney_L.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_L.glb" xsd:anyURI
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0004539
name: right kidney
namespace: uberon
def: "A kidney that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
xref: EMAPA:36590
xref: FMA:7204
xref: MA:0001683
xref: NCIT:C34005
xref: SCTID:362208000
xref: UMLS:C0227613 {source="ncithesaurus:Right_Kidney"}
is_a: UBERON:0002113 ! kidney
intersection_of: UBERON:0002113 ! kidney
intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism
relationship: in_right_side_of UBERON:0000468 ! multicellular organism
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Kidney_Right.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Kidney_R.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_R.glb" xsd:anyURI
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0004544
name: epididymis epithelium
namespace: uberon
def: "The layer of secretory cells which lines the epididymis." [MGI:csmith, MP:0004933]
subset: pheno_slim
synonym: "epididymis epithelium" EXACT [FMA:19153]
synonym: "epithelium of epididymis" EXACT [FMA:19153]
xref: BTO:0005768
xref: CALOHA:TS-2063
xref: EMAPA:30445
xref: FMA:19153
xref: MA:0002825
is_a: UBERON:0000485 ! simple columnar epithelium
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0012275 ! meso-epithelium
is_a: UBERON:0034969 ! epithelial layer of duct
intersection_of: UBERON:0000485 ! simple columnar epithelium
intersection_of: part_of UBERON:0001301 ! epididymis
relationship: contributes_to_morphology_of UBERON:0001301 ! epididymis
relationship: part_of UBERON:0001301 ! epididymis

[Term]
id: UBERON:0004548
name: left eye
namespace: uberon
def: "An eye that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "left eyeball" EXACT [FMA:12515]
synonym: "left orbital part of face" NARROW [FMA:54450]
synonym: "left orbital region" NARROW [FMA:54450]
xref: EMAPA:37362 {source="MA:th"}
xref: FMA:12515
xref: MA:0002949
xref: NCIT:C119334
xref: SCTID:362503005
is_a: UBERON:0000970 ! eye
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0000970 ! eye
intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-eye-l.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-eye-l.glb" xsd:anyURI
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0004549
name: right eye
namespace: uberon
def: "An eye that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "right eyeball" EXACT [FMA:12514]
synonym: "right orbital part of face" NARROW [FMA:54449]
synonym: "right orbital region" NARROW [FMA:54449]
xref: EMAPA:37363 {source="MA:th"}
xref: FMA:12514
xref: MA:0002950
xref: NCIT:C119333
xref: SCTID:362502000
is_a: UBERON:0000970 ! eye
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0000970 ! eye
intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism
relationship: in_right_side_of UBERON:0000468 ! multicellular organism
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-eye-r.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-eye-r.glb" xsd:anyURI
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0004571
name: systemic arterial system
namespace: uberon
def: "The part of the arterial system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Systemic_circulation#Arteries]
subset: pheno_slim
synonym: "systemic arterial circulatory system" EXACT [FMA:45623]
xref: FMA:45623
xref: Wikipedia:Systemic_circulation#Arteries
is_a: UBERON:0007798 {source="MA-inferred"} ! vascular system
relationship: part_of UBERON:0004572 ! arterial system

[Term]
id: UBERON:0004572
name: arterial system
namespace: uberon
def: "The part of the cardiovascular system consisting of all arteries." [https://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
xref: BTO:0004690
xref: EHDAA2:0000143
xref: EHDAA:396
xref: EMAPA:16201
xref: EMAPA:16371
xref: MA:0002719
xref: SCTID:362030008
xref: VHOG:0000273
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0007798 {source="MA"} ! vascular system
relationship: has_member UBERON:0001637 ! artery
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000273", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2005)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004573
name: systemic artery
namespace: uberon
def: "An artery of the systemic circulation, which is the part of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Artery#Systemic_arteries]
subset: human_reference_atlas
subset: pheno_slim
synonym: "systemic arterial subtree" EXACT [FMA:66464]
xref: EMAPA:37126 {source="MA:th"}
xref: FMA:66464
xref: Wikipedia:Artery#Systemic_arteries
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: part_of UBERON:0004571 ! systemic arterial system
relationship: part_of UBERON:0004571 ! systemic arterial system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004581
name: systemic venous system
namespace: uberon
def: "The part of the venous system that drains the general body tissues[Kardong]." [ISBN:0073040584, Wikipedia:Systemic_venous_system]
synonym: "systemic venous circulatory system" EXACT [FMA:45626]
xref: FMA:45626
xref: Wikipedia:Systemic_venous_system
is_a: UBERON:0002049 ! vasculature
relationship: part_of UBERON:0004582 ! venous system
property_value: UBPROP:0000001 "In human anatomy, the systemic venous system refers to veins that drain into the right atrium without passing through two vascular beds (i.e. they originate from a set of capillaries and do not pass through a second set of capillaries before reaching the right side of the heart). The term systemic venous system is often used to differentiate veins from veins that drain the pulmonary system (the pulmonary venous system) and veins that drain the digestive tract (the portal venous system). Large veins that are considered part of the systemic venous system are the: Superior vena cava; Inferior vena cava[WP]" xsd:string {source="Wikipedia:Systemic_venous_system"}
property_value: UBPROP:0000001 "Subdivision of cardiovascular system which has as its parts the right side of heart, the superior vena cava and the inferior vena cava[FMA]" xsd:string {ontology="FMA", source="FMA:45626"}
property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000277", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2005)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004582
name: venous system
namespace: uberon
def: "The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions." [https://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
synonym: "vein system" EXACT []
xref: BTO:0004692
xref: EHDAA2:0002171
xref: EHDAA:486
xref: EMAPA:16240
xref: MA:0002720
xref: NCIT:C33858
xref: SCTID:362060003
xref: UMLS:C1267406 {source="ncithesaurus:Venous_System"}
xref: VHOG:0000277
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0007798 {source="MA"} ! vascular system
relationship: composed_primarily_of UBERON:0001638 ! vein
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000277", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2005)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004590
name: sphincter muscle
namespace: uberon
def: "A structure, usually a circular muscle, that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning." [Wikipedia:Sphincter]
synonym: "circular muscle" RELATED []
synonym: "sphincter" EXACT []
xref: FMA:75004
xref: NCIT:C28381
xref: UMLS:C1409894 {source="ncithesaurus:Sphincter"}
xref: Wikipedia:Sphincter
is_a: UBERON:0001630 ! muscle organ
property_value: UBPROP:0000012 "FMA class is not a subtype of muscle" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0004638
name: blood vessel endothelium
namespace: uberon
def: "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart." [https://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: vertebrate_core
xref: BTO:0000766
xref: CALOHA:TS-2155
xref: EMAPA:35176
xref: MA:0000709
xref: NCIT:C53395
xref: TAO:0005257
xref: UMLS:C1706972 {source="ncithesaurus:Blood_Vessel_Endothelium"}
xref: ZFA:0005257
is_a: UBERON:0004852 ! cardiovascular system endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0001981 ! blood vessel
relationship: part_of UBERON:0001981 ! blood vessel
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004647
name: liver lobule
namespace: uberon
def: "The polygonal structure of the liver that consists of hepatocytes radiating outward from a hepatic vein." [ISBN:0-683-40008-8, MP:0008987]
subset: human_reference_atlas
subset: pheno_slim
synonym: "hepatic lobule" EXACT [FMA:14471]
synonym: "lobules of liver" RELATED OMO:0003004 [Wikipedia:Lobules_of_liver]
synonym: "lobuli hepatici" EXACT OMO:0003004 []
synonym: "lobuli hepatis" RELATED OMO:0003011 [Wikipedia:Lobules_of_liver]
synonym: "lobulus hepaticus" EXACT OMO:0003011 [FMA:14471]
xref: EMAPA:35499
xref: FMA:14471
xref: MA:0002494
xref: NCIT:C32732
xref: SCTID:362194004
xref: UMLS:C0227518 {source="ncithesaurus:Hepatic_Lobule"}
xref: Wikipedia:Lobules_of_liver
is_a: UBERON:0000064 {source="FMA"} ! organ part
is_a: UBERON:0004119 ! endoderm-derived structure
relationship: contributes_to_morphology_of UBERON:0001280 ! liver parenchyma
relationship: has_part CL:0000182 ! hepatocyte
relationship: part_of UBERON:0001280 {source="FMA", source="MA"} ! liver parenchyma
property_value: curator_notes "should not be confused with the anatomic lobes of the liver (caudate lobe, quadrate lobe, left lobe, and right lobe), or any of the functional lobe classification systems.[WP]" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004663
name: aorta wall
namespace: uberon
def: "An anatomical wall that is part of an aorta, enclosing the luminal space." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "aortic wall" EXACT [FMA:14156]
synonym: "wall of aorta" EXACT [FMA:14156]
xref: EMAPA:35139
xref: FMA:14156
xref: MA:0002901
is_a: UBERON:0035965 ! wall of blood vessel
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000947 ! aorta
relationship: contributes_to_morphology_of UBERON:0000947 ! aorta
relationship: part_of UBERON:0000947 ! aorta

[Term]
id: UBERON:0004664
name: aorta tunica adventitia
namespace: uberon
def: "The outermost layer of the aorta wall, containing connective tissue and collagen and elastic fibers." [ISBN:0-683-40008-8, MP:0009871]
subset: pheno_slim
synonym: "tunica adventitia of aorta" EXACT [FMA:14283]
xref: EMAPA:35136
xref: FMA:14283
xref: MA:0002902
xref: SCTID:24996002
is_a: UBERON:0005734 ! tunica adventitia of blood vessel
intersection_of: UBERON:0005734 ! tunica adventitia of blood vessel
intersection_of: part_of UBERON:0000947 ! aorta
relationship: contributes_to_morphology_of UBERON:0004663 ! aorta wall
relationship: part_of UBERON:0004663 ! aorta wall

[Term]
id: UBERON:0004665
name: muscular coat of seminal vesicle
namespace: uberon
def: "A muscular coat that is part of a seminal vesicle [Automatically generated definition]." [OBOL:automatic]
synonym: "muscle layer of seminal vesicle" EXACT [FMA:19404]
synonym: "muscular coat of seminal gland" EXACT [FMA:19404]
synonym: "muscular layer of seminal gland" EXACT [FMA:19404]
synonym: "tunica muscularis (vesicula seminalis)" EXACT [FMA:19404]
synonym: "tunica muscularis glandulae vesiculosae" EXACT OMO:0003011 [FMA:19404, FMA:TA]
xref: EMAPA:29773
xref: FMA:19404
xref: MA:0002913
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0006660 ! muscular coat
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0000998 ! seminal vesicle
relationship: part_of UBERON:0000998 ! seminal vesicle

[Term]
id: UBERON:0004666
name: interventricular septum membranous part
namespace: uberon
alt_id: UBERON:0004143
def: "The membranous portion of the wall between the two lower chambers of the heart." [MP:0008823]
subset: pheno_slim
synonym: "cardiac ventricular membranous septum" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "membranous interventricular septum" EXACT [FMA:7135]
synonym: "membranous interventricular septum" RELATED [MA:0002939]
synonym: "membranous part interventricular septum" EXACT [VHOG:0000927]
synonym: "membranous part of interventricular septum" EXACT [FMA:7135]
synonym: "membranous portion of interventricular septum" EXACT [FMA:7135]
synonym: "membranous septum" BROAD [GO:0003149]
synonym: "pars membranacea (septi interventricularis)" EXACT [FMA:7135]
synonym: "pars membranacea septi interventricularis" EXACT OMO:0003011 [FMA:7135, FMA:TA]
synonym: "ventricle membranous septum" BROAD [VT:0000018]
synonym: "ventricular membranous septum" BROAD [MP:0008823]
xref: EHDAA2:0004596
xref: EMAPA:18246
xref: FMA:7135
xref: MA:0002939
xref: SCTID:278228007
xref: VHOG:0000927
is_a: UBERON:0000158 ! membranous layer
is_a: UBERON:0005983 ! heart layer
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0000158 ! membranous layer
intersection_of: part_of UBERON:0002094 ! interventricular septum
relationship: contributes_to_morphology_of UBERON:0002094 ! interventricular septum
relationship: develops_from UBERON:0000095 {source="Wikipedia"} ! cardiac neural crest
relationship: part_of UBERON:0002094 ! interventricular septum
property_value: UBPROP:0000001 "The membranous septum is the upper part of ventricular septum[GO:0003149]." xsd:string {source="GO:0003149"}

[Term]
id: UBERON:0004667
name: interventricular septum muscular part
namespace: uberon
alt_id: UBERON:0004144
def: "The muscular portion of the wall between the two lower chambers of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Interventricular_septum#Portions]
subset: pheno_slim
synonym: "cardiac ventricular muscular septum" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "muscular interventricular septum" EXACT [FMA:7134]
synonym: "muscular interventricular septum" RELATED [MA:0002940]
synonym: "muscular part interventricular septum" EXACT []
synonym: "muscular part of interventricular septum" EXACT [FMA:7134]
synonym: "muscular septum" BROAD [GO:0003150]
synonym: "pars muscularis (septi interventricularis)" EXACT [FMA:7134]
synonym: "pars muscularis septi interventricularis" EXACT OMO:0003011 [FMA:7134, FMA:TA]
synonym: "septum membranaceum" EXACT OMO:0003011 []
synonym: "ventricular muscular septum" EXACT []
xref: EHDAA2:0000885
xref: EHDAA:2607
xref: EMAPA:18247
xref: FMA:7134
xref: MA:0002940
xref: RETIRED_EHDAA2:0000888
is_a: UBERON:0002385 ! muscle tissue
intersection_of: UBERON:0002385 ! muscle tissue
intersection_of: part_of UBERON:0002094 ! interventricular septum
relationship: contributes_to_morphology_of UBERON:0002094 ! interventricular septum
relationship: part_of UBERON:0002094 ! interventricular septum
property_value: UBPROP:0000001 "The muscular septum is the lower part of the ventricular septum[GO]" xsd:string {source="GO:0003150"}

[Term]
id: UBERON:0004684
name: raphe nuclei
namespace: uberon
def: "The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane." [https://sourceforge.net/tracker/?func=detail&aid=3248146&group_id=36855&atid=440764, NLXANAT:20090205]
comment: we treat NR obscurus, NR magnus etc as parts of the raphe nuclei. This is consistent with treatment in FMA, where the class is 'set of raphe nuclei'
subset: vertebrate_core
synonym: "nuclei raphes" EXACT OMO:0003011 [FMA:84017, FMA:TA]
synonym: "nuclei raphes" RELATED OMO:0003011 [Wikipedia:Raphe_nuclei]
synonym: "raphe cluster" RELATED [Wikipedia:Raphe_nuclei]
synonym: "raphe nuclei" EXACT [FMA:84017, NLXANAT:20090205]
synonym: "raphe nuclei set" EXACT [FMA:84017]
synonym: "raphe nucleus" RELATED [ZFA:0001429]
synonym: "raphe of mesenchephalon" RELATED [BAMS:RA]
synonym: "set of raphe nuclei" RELATED [FMA:84017]
xref: BAMS:RA
xref: EMAPA:35721
xref: FMA:84017
xref: MA:0003147
xref: MESH:D011903
xref: NCIT:C97335
xref: neuronames:2495
xref: NLXANAT:20090205
xref: TAO:0001429
xref: UMLS:C0034671 {source="ncithesaurus:Raphe_Nuclei"}
xref: Wikipedia:Raphe_nuclei
xref: ZFA:0001429
is_a: UBERON:0002616 ! regional part of brain
relationship: capable_of GO:0001820 {source="Wikipedia"} ! serotonin secretion
relationship: part_of UBERON:0002275 {source="GO", source="Wikipedia"} ! reticular formation
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png" xsd:anyURI

[Term]
id: UBERON:0004688
name: costo-cervical trunk
namespace: uberon
def: "The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted]." [Wikipedia:Costocervical_trunk]
subset: human_reference_atlas
synonym: "costocervical trunk" EXACT [FMA:10636]
synonym: "truncus costocervicalis" RELATED OMO:0003011 [Wikipedia:Costocervical_trunk]
synonym: "trunk of costocervical artery" EXACT [FMA:10636]
xref: EMAPA:37496 {source="MA:th"}
xref: FMA:10636
xref: MA:0001939
xref: SCTID:244225009
xref: Wikipedia:Costocervical_trunk
is_a: UBERON:0001637 ! artery
relationship: connected_to UBERON:0001533 ! subclavian artery
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b3/Costocervical_trunk_with_branches.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004695
name: arterial system smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of an arterial system [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:36503
xref: MA:0000704
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0004572 ! arterial system
relationship: part_of UBERON:0004572 ! arterial system

[Term]
id: UBERON:0004696
name: venous system smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a venous system [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:36613
xref: MA:0000715
is_a: UBERON:0004237 ! blood vessel smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0004582 ! venous system
relationship: part_of UBERON:0004237 ! blood vessel smooth muscle
relationship: part_of UBERON:0004582 ! venous system

[Term]
id: UBERON:0004698
name: vena cava endothelium
namespace: uberon
def: "An endothelium that is part of a vena cava [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:37800 {source="MA:th"}
xref: MA:0000713
xref: NCIT:C49318
xref: UMLS:C1710623 {source="ncithesaurus:Vena_Cava_Endothelium"}
is_a: UBERON:0001919 ! endothelium of vein
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0004087 ! vena cava
relationship: part_of UBERON:0004087 ! vena cava

[Term]
id: UBERON:0004699
name: outflow tract endothelium
namespace: uberon
def: "An endothelium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic]
xref: MA:0000490
xref: VHOG:0001524
is_a: UBERON:0008307 ! heart endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0004145 ! outflow tract
relationship: part_of UBERON:0004145 ! outflow tract
property_value: UBPROP:0000003 "It is assumed that during evolution, a circulatory system composed of the heart and endothelial tubular system first formed in vertebrates, medial smooth muscle then appeared for regulation of the system, and innervation of the muscle tissue took place. This sequence of development assumed for phylogenesis is actually realized in the ontogenetic processes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001524", ontology="VHOG", source="DOI:10.1254/jjp.87.253 Shigei T, Tsuru H, Ishikawa N, Yoshioka K, Absence of endothelium in invertebrate blood vessels: significance of endothelium and sympathetic nerve/medial smooth muscle in the vertebrate vascular system. Japanese Journal of Pharmacology (2001)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004700
name: arterial system endothelium
namespace: uberon
def: "An endothelium that is part of an arterial system [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:35145
xref: MA:0000703
xref: NCIT:C49329
xref: UMLS:C1706849 {source="ncithesaurus:Arterial_System_Endothelium"}
is_a: UBERON:0004852 ! cardiovascular system endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0004572 ! arterial system
relationship: part_of UBERON:0004572 ! arterial system

[Term]
id: UBERON:0004701
name: venous system endothelium
namespace: uberon
def: "An endothelium that is part of a venous system [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:35907
xref: MA:0000714
xref: NCIT:C49320
xref: UMLS:C1710626 {source="ncithesaurus:Venous_System_Endothelium"}
is_a: UBERON:0004852 ! cardiovascular system endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0004582 ! venous system
relationship: part_of UBERON:0004582 ! venous system

[Term]
id: UBERON:0004702
name: respiratory system blood vessel endothelium
namespace: uberon
def: "A blood vessel endothelium that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:35732
xref: MA:0001805
is_a: UBERON:0004638 ! blood vessel endothelium
is_a: UBERON:0004807 ! respiratory system epithelium
intersection_of: UBERON:0004638 ! blood vessel endothelium
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0003504 ! respiratory system blood vessel

[Term]
id: UBERON:0004706
name: bulbus cordis
namespace: uberon
def: "A transient fetal dilation of the distal (or cranial) heart tube located where the arterial trunk joins the ventral roots of the aortic arches." [ISBN:0-683-40008-8, MP:0010568]
subset: pheno_slim
subset: vertebrate_core
synonym: "primitive right ventricle endocardium" EXACT [EHDAA2:0000197]
xref: EHDAA2:0000197
xref: EHDAA:438
xref: EHDAA:768
xref: EMAPA:16333
xref: FMA:70300
xref: NCIT:C34114
xref: SCTID:361525002
xref: UMLS:C1284055 {source="ncithesaurus:Bulbus_Cordis"}
xref: Wikipedia:Bulbus_cordis
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0000948 ! heart
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/c/c9/Gray466.png" xsd:anyURI
property_value: editor_note "TODO - check relationship to bulbus arteriosus" xsd:string
property_value: UBPROP:0000001 "A pear shaped chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches. The bulbus arteriosus has three distinct layers. Hu et al. 2000.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000173", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0004707
name: pharyngula stage
namespace: uberon
def: "A stage that follows the blastula, gastrula and neurula stages. At the pharyngula stage, all vertebrate embryos show remarkable similarities." [Wikipedia:Pharyngula]
subset: efo_slim
synonym: "pharyngula" RELATED []
synonym: "phylotypic stage" EXACT []
xref: DrerDO:0000052
xref: EFO:0001310
xref: OGES:000006
xref: Wikipedia:Pharyngula
xref: ZFS:0000050
is_a: UBERON:0000105 ! life cycle stage
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000111 ! organogenesis stage
relationship: preceded_by UBERON:0000110 ! neurula stage
property_value: UBPROP:0000008 "Corresponds to E7-E11 in Mouse (Galis et al, TREE, 2001)" xsd:string

[Term]
id: UBERON:0004708
name: paired limb/fin
namespace: uberon
alt_id: UBERON:0009872
def: "An appendage that is part of an appendage girdle complex." [https://github.com/geneontology/go-ontology/issues/9029, UBERON:cjm]
subset: homology_grouping
synonym: "girdle-associated appendage" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "jointed paired lateral appendage" NARROW [https://orcid.org/0000-0002-6601-2165]
synonym: "limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "limb/fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "paired appendage" NARROW [VSAO:0000067]
synonym: "pectoral or pelvic appendage" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "pelvic/pectoral appendage" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: VSAO:0000067
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000026 {source="VSAO"} ! appendage
intersection_of: UBERON:0000026 ! appendage
intersection_of: part_of UBERON:0010707 ! appendage girdle complex
relationship: connected_to UBERON:0007823 ! appendage girdle region
relationship: develops_from UBERON:0004357 {evidence="definitional"} ! paired limb/fin bud
relationship: has_part UBERON:0000014 ! zone of skin
relationship: has_part UBERON:0001015 ! musculature
relationship: has_part UBERON:0002049 ! vasculature
relationship: has_skeleton UBERON:0011582 ! paired limb/fin skeleton
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0010707 {source="VSAO"} ! appendage girdle complex
property_value: curator_notes "this class is the union of the classes limb, pectoral fin and pelvic fin." xsd:string

[Term]
id: UBERON:0004709
name: pelvic appendage
namespace: uberon
alt_id: UBERON:0009876
def: "Paired appendage that consists of the posterior appendicular skeleton and associated soft and hard tissues, but excludes the pelvic girdle and its associated soft and hard tissues." [VSAO:0000150]
subset: homology_grouping
synonym: "hindlimb/pelvic fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "pelvic appendage" EXACT [VSAO:0000126]
synonym: "pelvic limb/fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "posterior appendage" BROAD []
synonym: "posterior limb/fin" EXACT []
synonym: "posterior paired appendage" EXACT [VSAO:0000126]
xref: VSAO:0000126
is_a: UBERON:0004708 ! paired limb/fin
intersection_of: UBERON:0004708 ! paired limb/fin
intersection_of: part_of UBERON:0010709 ! pelvic complex
disjoint_from: UBERON:0004710 {source="lexical"} ! pectoral appendage
relationship: connected_to UBERON:0001271 ! pelvic girdle region
relationship: develops_from UBERON:0005420 {evidence="definitional"} ! pelvic appendage bud
relationship: has_skeleton UBERON:0007273 ! pelvic appendage skeleton
relationship: part_of UBERON:0010709 ! pelvic complex

[Term]
id: UBERON:0004710
name: pectoral appendage
namespace: uberon
alt_id: UBERON:0009875
def: "Paired appendage that consists of the anterior appendicular skeleton and associated soft and hard tissues, but excludes the pectoral girdle and its associated soft and hard tissues." [VSAO:0000150-modified]
subset: homology_grouping
synonym: "anterior appendage" BROAD []
synonym: "anterior limb/fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "anterior paired appendage" EXACT [VSAO:0000148]
synonym: "forelimb - pectoral fin" EXACT [VHOG:0001753]
synonym: "forelimb or pectoral fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "forelimb/pectoral fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "pectoral limb/fin" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: VHOG:0001753
xref: VSAO:0000125
is_a: UBERON:0004708 ! paired limb/fin
intersection_of: UBERON:0004708 ! paired limb/fin
intersection_of: part_of UBERON:0010708 ! pectoral complex
relationship: connected_to UBERON:0001421 ! pectoral girdle region
relationship: develops_from UBERON:0005419 {evidence="definitional"} ! pectoral appendage bud
relationship: has_skeleton UBERON:0007272 ! pectoral appendage skeleton
relationship: part_of UBERON:0010708 ! pectoral complex
property_value: UBPROP:0000003 "While the skeletons of teleost pectoral fins and tetrapod forelimbs are homologous at the level of endoskeletal radials, teleosts and tetrapods do not share homologous skeletal elements at the level of 'individuated' pro-, meso-, and metapterygia. Among osteichthyans, only basal actinopterygians retain the full complement of elements present in non-osteichthyan gnathostomes.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001753", ontology="VHOG", source="DOI:10.1002/jmor.10264 Davis MC, Shubin NH, Force A, Pectoral fin and girdle development in the basal actinopterygians Polyodon spathula and Acipenser transmontanus. Journal of Morphology (2004)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004711
name: jugular vein
namespace: uberon
def: "The jugular veins are veins that bring deoxygenated blood from the head back to the heart via the superior vena cava." [Wikipedia:Jugular_vein]
synonym: "jugular" RELATED []
synonym: "vena jugularis" RELATED [BTO:0001744]
xref: BTO:0001744
xref: CALOHA:TS-0497
xref: EMAPA:18638
xref: GAID:536
xref: MA:0002154
xref: MESH:D007601
xref: NCIT:C12738
xref: SCTID:244403000
xref: UMLS:C0022427 {source="ncithesaurus:Jugular_Vein"}
xref: Wikipedia:Jugular_vein
is_a: UBERON:0001638 ! vein
relationship: drains UBERON:0000033 ! head
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0000974 {gci_filler="NCBITaxon:8287", gci_relation="in_taxon"} ! neck
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f8/Gray558.png" xsd:anyURI

[Term]
id: UBERON:0004716
name: conceptus
namespace: uberon
def: "The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]." [BTO:0003834, Wikipedia:Conceptus]
synonym: "embryo plus adnexa" EXACT []
xref: AEO:0000194
xref: BTO:0003834
xref: EHDAA2:0000001
xref: EHDAA2:0003235
xref: EMAPA:36040
xref: NCIT:C34131
xref: UMLS:C1516779 {source="ncithesaurus:Conceptus"}
xref: Wikipedia:Conceptus
is_a: UBERON:0000061 ! anatomical structure
relationship: develops_from CL:0000365 ! animal zygote
relationship: existence_ends_with UBERON:0000068 ! embryo stage
relationship: existence_starts_with UBERON:0000068 ! embryo stage
relationship: has_part UBERON:0002050 ! embryonic structure
relationship: has_part UBERON:0016887 ! entire extraembryonic component
property_value: editor_note "EHDAA2 places this as a subtype of organism. This leads to the inference that a conceptus is an embryo (if an embryo is defined as an organism at embryo stage), which eliminates the embryonic + extra-embryonic = conceptus" xsd:string

[Term]
id: UBERON:0004729
name: nematode larval stage
namespace: uberon
def: "Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GO:0002119]
xref: WBls:0000023
is_a: UBERON:0000069 ! larval stage
relationship: only_in_taxon NCBITaxon:6231 ! Nematoda
relationship: simultaneous_with GO:0002119 ! nematode larval development
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/567" xsd:anyURI

[Term]
id: UBERON:0004731
name: neuromere
namespace: uberon
def: "A transverse unitary subdivision of the neural tube that shares a common dorsoventral structure (floor, basal, alar, and roof plates), but each having differential molecular identities and fates; they comprise the secondary prosencephalon, diencephalon (prosomeres), the midbrain (mesomeres), and the hindbrain (rhombomeres)." [DOI:10.1016/j.tins.2013.06.004, https://github.com/obophenotype/uberon/issues/318]
subset: pheno_slim
synonym: "neural metamere" RELATED []
synonym: "neural segment" RELATED []
synonym: "neural tube metameric segment" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "neural tube segment" EXACT []
synonym: "neuromere" EXACT []
synonym: "neuromeres" EXACT OMO:0003004 [TAO:0001328]
xref: NLX:147842
xref: TAO:0001328
xref: Wikipedia:Neuromere
xref: ZFA:0001328
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0004732 ! segmental subdivision of nervous system
intersection_of: UBERON:0004732 ! segmental subdivision of nervous system
intersection_of: part_of UBERON:0001049 ! neural tube
relationship: part_of UBERON:0001049 ! neural tube
property_value: editor_note "We take the definition of neuromere from Puelles et al, although the existence of mesomeres and prosomeres may not be widely accepted" xsd:string
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-9114-8737
property_value: UBPROP:0000001 "A metameric segment of the central nervous system.[ZFA]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001328", ontology="TAO", source="ZFIN:curator"}
creation_date: 2009-06-18T09:00:04Z

[Term]
id: UBERON:0004732
name: segmental subdivision of nervous system
namespace: uberon
def: "Any segmental subdivision of a nervous system. Includes metameric developmental segments, such as vertebrates neuromeres." [FBbt:00005140, http://orcid.org/0000-0002-6601-2165]
subset: non_informative
synonym: "neuromere" RELATED [FBbt:00005140]
is_a: UBERON:0000063 ! organ subunit
intersection_of: UBERON:0000063 ! organ subunit
intersection_of: part_of UBERON:0001016 ! nervous system
relationship: part_of UBERON:0001016 ! nervous system
property_value: editor_note "revisit this after CARO is revised and/or we have defined metameric segment; note that with the additional of an A/P axis constraint this corresponds to what Richter at al call a neuromere (PMID:21062451)" xsd:string

[Term]
id: UBERON:0004733
name: segmental subdivision of hindbrain
namespace: uberon
def: "An organ subunit that is part of a hindbrain [Automatically generated definition]." [OBOL:automatic]
subset: non_informative
synonym: "hindbrain segment" EXACT [FMA:61998]
synonym: "segment of hindbrain" EXACT [FMA:61998]
xref: FMA:61998
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0004732 ! segmental subdivision of nervous system
intersection_of: UBERON:0000063 ! organ subunit
intersection_of: part_of UBERON:0002028 ! hindbrain
relationship: part_of UBERON:0002028 ! hindbrain

[Term]
id: UBERON:0004734
name: gastrula
namespace: uberon
alt_id: UBERON:0007012
def: "Organism at the gastrula stage." [Wikipedia:Gastrula, Wikipedia:Trilaminar_blastocyst]
subset: pheno_slim
synonym: "blastocystis trilaminaris" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "gastrula embryo" EXACT [BILA:0000060]
synonym: "tri-laminar disc" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "tri-laminar disk" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "trilaminar blastocyst" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "trilaminar blastoderm" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "trilaminar disc" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165]
xref: BILA:0000060
xref: BTO:0001403
xref: FBbt:00005317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:293108
xref: GAID:1302
xref: MESH:D005775
xref: MIAA:0000179
xref: NCIT:C34057
xref: NCIT:C34058
xref: UMLS:C0017199 {source="ncithesaurus:Gastrula"}
xref: UMLS:C1284022 {source="ncithesaurus:Trilaminar_Embryonic_Disc"}
xref: Wikipedia:Gastrula
xref: Wikipedia:Trilaminar_blastocyst
is_a: UBERON:0000922 ! embryo
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: existence_starts_and_ends_during UBERON:0000109 ! gastrula stage
relationship: develops_from UBERON:0000307 ! blastula
relationship: existence_starts_and_ends_during UBERON:0000109 ! gastrula stage
property_value: UBPROP:0000012 "We explicitly merge the NCITA terms here" xsd:string {external_ontology="NCIT"}

[Term]
id: UBERON:0004737
name: metanephric collecting duct
namespace: uberon
def: "A collecting duct of renal tubule that is part of a metanephros [Automatically generated definition]." [OBOL:automatic]
synonym: "collecting duct of metanephros" EXACT []
synonym: "metanephric collecting tubule" RELATED [VHOG:0000983]
xref: VHOG:0000983
is_a: UBERON:0001232 ! collecting duct of renal tubule
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0001232 ! collecting duct of renal tubule
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: develops_from UBERON:0003220 {source="Wikipedia-abduced"} ! metanephric mesenchyme
relationship: develops_from UBERON:0014706 ! primitive renal collecting duct system
relationship: part_of UBERON:0005110 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric nephron

[Term]
id: UBERON:0004755
name: skeletal tissue
namespace: uberon
def: "A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/134, PSPUB:0000170, VSAO:0000015]
comment: Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from
xref: EMAPA:37744 {source="MA:th"}
xref: MA:0003047
xref: SCTID:309311006
xref: VSAO:0000015
xref: XAO:0004038
xref: ZFA:0005619
is_a: UBERON:0002384 {source="VSAO"} ! connective tissue
relationship: develops_from CL:0007001 {date_retrieved="2012-08-14", external_class="VSAO:0000015", source="VSAO"} ! skeletogenic cell
relationship: part_of UBERON:0004765 ! skeletal element
property_value: UBPROP:0000001 "A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000015", notes="taken from version of VSAO used in TAO and used directly in Uberon", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"}

[Term]
id: UBERON:0004756
name: dermal skeletal element
namespace: uberon
def: "Dermis-derived entity that is made of skeletal tissue." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/206]
synonym: "dermal element" EXACT [VSAO:curator]
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0004765 ! skeletal element
intersection_of: UBERON:0004765 ! skeletal element
intersection_of: develops_from UBERON:0002067 ! dermis
intersection_of: has_part UBERON:0004755 ! skeletal tissue
relationship: develops_from UBERON:0002067 ! dermis
relationship: has_part UBERON:0004755 ! skeletal tissue

[Term]
id: UBERON:0004760
name: gland of anal canal
namespace: uberon
def: "A gland that is part of an anal canal [Automatically generated definition]." [OBOL:automatic, Wikipedia:Anal_gland]
subset: human_reference_atlas
subset: organ_slim
synonym: "anal gland" RELATED []
synonym: "anal sac" RELATED SENSU [Wikipedia:Anal_gland]
synonym: "gland of anal sac" RELATED []
synonym: "gland of anus" RELATED []
synonym: "rectal gland" RELATED []
xref: EMAPA:27221
xref: EMAPA:27233
xref: EMAPA:27543
xref: FMA:15720
xref: FMA:15724
xref: NCIT:C32068
xref: SCTID:245448005
xref: UMLS:C0162322 {source="ncithesaurus:Anal_Gland"}
xref: Wikipedia:Anal_gland
is_a: UBERON:0003408 ! gland of digestive tract
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0000159 ! anal canal
relationship: part_of UBERON:0000159 ! anal canal
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004761
name: cartilaginous neurocranium
namespace: uberon
def: "The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]." [Wikipedia:Chondrocranium]
synonym: "cartilaginous chondocranium" EXACT []
synonym: "cartilaginous skull" RELATED []
synonym: "cartiligionous skeletal structure of skull" EXACT []
synonym: "chondocranium" RELATED [Wikipedia:Chondrocranium]
synonym: "embryonic chondocranium" RELATED []
synonym: "neurocranium" RELATED SENSU []
xref: AAO:0000094
xref: AAO:0010153
xref: EHDAA:6031
xref: FMA:76621
xref: NCIT:C34121
xref: SCTID:155540009
xref: UMLS:C1516496 {source="ncithesaurus:Chondrocranium"}
xref: Wikipedia:Chondrocranium
xref: XAO:0003059
is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system
relationship: develops_from UBERON:0009617 {source="PMC1571569"} ! head paraxial mesoderm
relationship: has_part UBERON:0002418 ! cartilage tissue
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
property_value: UBPROP:0000012 "in contrast to chondrocranium, this structure is entirely cartiliginous. In Chondricthyes this is the same as the neurocranium. FMA:76621 is an undefined fetal structure, so we assume the correct placement is here. Note that this is distinct from MA:0000317 which is the uberon:neurocranium (the part of the cranium that encloses the brain)" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0004764
name: intramembranous bone tissue
namespace: uberon
def: "Bone tissue that forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]." [GO:0001957, Wikipedia:Intramembranous_ossification]
xref: MA:0002837
xref: Wikipedia:Intramembranous_ossification
is_a: UBERON:0002481 ! bone tissue
intersection_of: UBERON:0002481 ! bone tissue
intersection_of: output_of GO:0001957 ! intramembranous ossification
relationship: develops_from UBERON:0003104 ! mesenchyme
relationship: output_of GO:0001957 ! intramembranous ossification
relationship: part_of UBERON:0002514 ! intramembranous bone
property_value: UBPROP:0000012 "note the distinction between intramembranous bone and intramembranous bone tissue. Some bones may be a mixture of both tissue types. The MA class most likely refers to a tissue type (it is under bone tissue and connective tissue; there are no child classes)" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0004765
name: skeletal element
namespace: uberon
def: "Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles." [https://orcid.org/0000-0002-6601-2165]
subset: organ_slim
subset: uberon_slim
xref: AAO:0011129
xref: galen:SkeletalStructure
xref: TAO:0001890
xref: VSAO:0000128
xref: XAO:0004012
xref: ZFA:0005494
is_a: UBERON:0000062 ! organ
relationship: part_of UBERON:0001434 {source="VSAO"} ! skeletal system
property_value: UBPROP:0000001 "Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000128", ontology="VSAO", source="PSPUB:0000170"}
property_value: UBPROP:0000001 "Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001890", ontology="TAO", source="TAO:VSAO_workshop"}

[Term]
id: UBERON:0004766
name: cranial bone
namespace: uberon
def: "A bone that is part of a cranium." [UBERON:automatic]
subset: human_reference_atlas
synonym: "cranium bone" EXACT [UBERON:automatic]
xref: SCTID:181792001
is_a: UBERON:0001474 ! bone element
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0003128 ! cranium
relationship: part_of UBERON:0003128 ! cranium
property_value: curator_notes "here cranium = skull - mandible" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004768
name: bone of lower jaw
namespace: uberon
def: "Any bone that is part of the lower jaw skeleton. This includes (when present): the dentary/mandible, the articular, the splenial, the suprangular." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "lower jaw bone" EXACT []
is_a: UBERON:0012360 ! bone of jaw
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0001710 ! lower jaw region
relationship: part_of UBERON:0003278 ! skeleton of lower jaw
property_value: editor_note "Do not manually classify under here - bones are automatically classified" xsd:string

[Term]
id: UBERON:0004770
name: articular system
namespace: uberon
def: "Anatomical system that consists of all the joints of the body." [VSAO:0000181]
synonym: "joint system" EXACT [FMA:23878]
synonym: "set of all joints" RELATED []
synonym: "set of all joints of body" EXACT [FMA:23878]
synonym: "set of joints of body" RELATED [FMA:23878]
xref: EMAPA:35150
xref: FMA:23878
xref: MA:0003007
xref: SCTID:361827000
xref: VSAO:0000181
is_a: UBERON:0034925 ! anatomical collection
intersection_of: UBERON:0034925 ! anatomical collection
intersection_of: has_member UBERON:0000982 ! skeletal joint
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: functionally_related_to GO:0040011 ! locomotion
relationship: has_member UBERON:0000982 ! skeletal joint
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
relationship: part_of UBERON:0001434 {source="FMA"} ! skeletal system

[Term]
id: UBERON:0004777
name: respiratory system submucosa
namespace: uberon
def: "A submucosa that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "submucosa of respiratory system" EXACT [OBOL:automatic]
xref: EMAPA:37578 {source="MA:th"}
xref: MA:0001822
is_a: UBERON:0000009 ! submucosa
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0003570 ! respiratory system connective tissue

[Term]
id: UBERON:0004779
name: respiratory system lamina propria
namespace: uberon
def: "A lamina propria that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "apparatus respiratorius lamina propria" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "lamina propria mucosa of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "lamina propria mucosa of respiratory system" EXACT [OBOL:automatic]
synonym: "lamina propria of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "lamina propria of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory system lamina propria mucosa" EXACT [OBOL:automatic]
xref: EMAPA:37576 {source="MA:th"}
xref: MA:0001821
is_a: UBERON:0000030 ! lamina propria
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0003570 ! respiratory system connective tissue
relationship: part_of UBERON:0004785 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! respiratory system mucosa

[Term]
id: UBERON:0004780
name: gastrointestinal system lamina propria
namespace: uberon
def: "A lamina propria that is part of a gastrointestinal system." [OBOL:automatic]
xref: MA:0001899
xref: NCIT:C49299
xref: UMLS:C1708197 {source="ncithesaurus:Gastrointestinal_Tract_Lamina_Propria"}
is_a: UBERON:0000030 ! lamina propria
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system
relationship: part_of UBERON:0004786 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! gastrointestinal system mucosa

[Term]
id: UBERON:0004781
name: gallbladder lamina propria
namespace: uberon
def: "A lamina propria that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic]
synonym: "biliary lamina propria" RELATED [MA:0001633]
synonym: "gall bladder lamina propria" EXACT [OBOL:automatic]
synonym: "gall bladder lamina propria mucosa" EXACT [OBOL:automatic]
synonym: "gallbladder lamina propria mucosa" EXACT []
synonym: "lamina propria mucosa of gall bladder" EXACT [OBOL:automatic]
synonym: "lamina propria mucosa of gallbladder" EXACT [OBOL:automatic]
synonym: "lamina propria of gall bladder" EXACT [OBOL:automatic]
synonym: "lamina propria of gallbladder" EXACT [OBOL:automatic]
xref: EMAPA:35371
xref: FMA:278594
xref: MA:0001633
xref: NCIT:C49228
xref: UMLS:C1708175 {source="ncithesaurus:Gallbladder_Lamina_Propria"}
is_a: UBERON:0000030 ! lamina propria
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0002110 ! gallbladder
relationship: part_of UBERON:0005033 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mucosa of gallbladder

[Term]
id: UBERON:0004782
name: gastrointestinal system serosa
namespace: uberon
def: "A serous membrane that is part of a digestive system [Automatically generated definition]." [OBOL:automatic]
synonym: "digestive system serosa" EXACT [OBOL:automatic]
synonym: "digestive system serous membrane" EXACT [OBOL:automatic]
synonym: "gastrointestinal system serous membrane" EXACT [OBOL:automatic]
synonym: "serosa of digestive system" EXACT [OBOL:automatic]
synonym: "serosa of gastrointestinal system" EXACT [OBOL:automatic]
synonym: "serous membrane of digestive system" EXACT [OBOL:automatic]
synonym: "serous membrane of gastrointestinal system" EXACT [OBOL:automatic]
xref: EMAPA:37592 {source="MA:th"}
xref: MA:0001522
is_a: UBERON:0000042 ! serous membrane
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system
relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system

[Term]
id: UBERON:0004783
name: gallbladder serosa
namespace: uberon
def: "A serous membrane that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic]
synonym: "biliary serosa" RELATED [MA:0001634]
synonym: "gall bladder serosa" EXACT [OBOL:automatic]
synonym: "gall bladder serous membrane" EXACT []
synonym: "gallbladder serous membrane" EXACT [OBOL:automatic]
synonym: "serosa of gall bladder" EXACT [OBOL:automatic]
synonym: "serosa of gallbladder" EXACT [OBOL:automatic]
synonym: "serous coat of gallbladder" EXACT [FMA:14659]
synonym: "serous membrane of gall bladder" EXACT [OBOL:automatic]
synonym: "serous membrane of gallbladder" EXACT [OBOL:automatic]
synonym: "tunica serosa (vesica biliaris)" EXACT [FMA:14659]
synonym: "tunica serosa vesicae biliaris" EXACT OMO:0003011 [FMA:14659, FMA:TA]
xref: EMAPA:35372
xref: FMA:14659
xref: MA:0001634
xref: SCTID:362197006
is_a: UBERON:0000042 ! serous membrane
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0002110 ! gallbladder
relationship: part_of UBERON:0002110 ! gallbladder

[Term]
id: UBERON:0004784
name: heart ventricle wall
namespace: uberon
def: "An anatomical wall that is part of a cardiac ventricle [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "anatomical wall of cardiac ventricle" EXACT [OBOL:automatic]
synonym: "anatomical wall of heart ventricle" EXACT [OBOL:automatic]
synonym: "anatomical wall of lower chamber of heart" EXACT [OBOL:automatic]
synonym: "anatomical wall of ventricle of heart" EXACT [OBOL:automatic]
synonym: "cardiac ventricle anatomical wall" EXACT [OBOL:automatic]
synonym: "cardiac ventricle wall" EXACT [OBOL:automatic]
synonym: "heart ventricle anatomical wall" EXACT [OBOL:automatic]
synonym: "lower chamber of heart anatomical wall" EXACT [OBOL:automatic]
synonym: "lower chamber of heart wall" EXACT [OBOL:automatic]
synonym: "ventricle of heart anatomical wall" EXACT [OBOL:automatic]
synonym: "ventricle of heart wall" EXACT [OBOL:automatic]
synonym: "ventricular wall" EXACT [FMA:13884]
synonym: "wall of cardiac ventricle" EXACT [OBOL:automatic]
synonym: "wall of heart ventricle" EXACT [OBOL:automatic]
synonym: "wall of lower chamber of heart" EXACT [OBOL:automatic]
synonym: "wall of ventricle" RELATED [MA:0002791]
synonym: "wall of ventricle of heart" EXACT [OBOL:automatic]
xref: FMA:13884
xref: MA:0002791
xref: NCIT:C119295
is_a: UBERON:0037144 ! wall of heart
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0002082 ! cardiac ventricle

[Term]
id: UBERON:0004785
name: respiratory system mucosa
namespace: uberon
def: "The mucous membrane lining the respiratory tract." [MESH:A04.760, MGI:cwg, MP:0002277]
subset: pheno_slim
synonym: "apparatus respiratorius mucosa" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius mucosa of organ" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius mucous membrane" EXACT [OBOL:automatic]
synonym: "laryngeal mucous membrane" RELATED [EMAPA:18334]
synonym: "mucosa of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "mucosa of organ of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "mucosa of organ of respiratory system" EXACT [OBOL:automatic]
synonym: "mucosa of respiratory system" EXACT [OBOL:automatic]
synonym: "mucous membrane of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "mucous membrane of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory mucosa" RELATED [BTO:0000973]
synonym: "respiratory system mucosa of organ" EXACT [OBOL:automatic]
synonym: "respiratory system mucous membrane" EXACT [OBOL:automatic]
synonym: "respiratory tract mucosa" RELATED []
xref: BTO:0000973
xref: EMAPA:18334
xref: EMAPA:37577 {source="MA:th"}
xref: FMA:302092
xref: GAID:304
xref: MA:0001827
xref: MESH:D020545
is_a: UBERON:0000344 ! mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0001004 ! respiratory system
property_value: editor_note "TODO - split respiratory tract mucosa from respiratory system mucosa" xsd:string

[Term]
id: UBERON:0004786
name: gastrointestinal system mucosa
namespace: uberon
def: "A mucosa that is part of a gastrointestinal system." [OBOL:automatic]
comment: The gut mucosa of amphioxus has insulin-secreting cells. http://www.ncbi.nlm.nih.gov/pubmed/16417468
synonym: "digestive tract mucosa" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "gut mucosa" EXACT [BTO:0000546]
synonym: "gut mucuous membrane" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "mucosa of gut" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: BTO:0000546
xref: BTO:0005568
xref: EMAPA:36591
xref: MA:0001521
xref: SCTID:410433007
is_a: UBERON:0000344 ! mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system
relationship: adjacent_to UBERON:0006909 {source="BTO-modified"} ! lumen of digestive tract
relationship: has_part CL:0000172 {source="PMID:16417468"} ! somatostatin secreting cell
relationship: has_part CL:0000696 {source="PMID:16417468"} ! PP cell
relationship: has_part CL:0002067 {source="PMID:16417468"} ! type A enteroendocrine cell
relationship: part_of UBERON:0001555 ! digestive tract
relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system

[Term]
id: UBERON:0004790
name: skin mucous gland
namespace: uberon
def: "A mucous gland that is part of the skin." [http://orcid.org/0000-0002-6601-2165]
subset: organ_slim
synonym: "mucous gland of entire skin" EXACT [OBOL:automatic]
synonym: "mucous gland of skin of body" EXACT [OBOL:automatic]
synonym: "skin mucus gland" EXACT [OBOL:automatic]
synonym: "skin of body mucous gland" EXACT [OBOL:automatic]
xref: EMAPA:35775
xref: MA:0000148
is_a: UBERON:0000414 ! mucous gland
is_a: UBERON:0007771 ! epidermis gland
is_a: UBERON:0019319 ! exocrine gland of integumental system
intersection_of: UBERON:0000414 ! mucous gland
intersection_of: part_of UBERON:0002097 ! skin of body
property_value: editor_note "See comments for 'skin mucus'" xsd:string

[Term]
id: UBERON:0004792
name: secretion of endocrine pancreas
namespace: uberon
def: "A secretion that is part of a endocrine pancreas [Automatically generated definition]." [OBOL:automatic]
synonym: "endocrine pancreas secretion" EXACT [OBOL:automatic]
synonym: "pancreatic endocrine secretion" EXACT [ncithesaurus:Pancreatic_Endocrine_Secretion]
synonym: "pars endocrina pancreatis secretion" EXACT [OBOL:automatic]
synonym: "secretion of pars endocrina pancreatis" EXACT [OBOL:automatic]
xref: MA:0002517
xref: NCIT:C33255
xref: UMLS:C1518866 {source="ncithesaurus:Pancreatic_Endocrine_Secretion"}
is_a: UBERON:0004795 ! pancreas secretion
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: part_of UBERON:0000016 ! endocrine pancreas
relationship: part_of UBERON:0000016 ! endocrine pancreas

[Term]
id: UBERON:0004793
name: secretion of exocrine pancreas
namespace: uberon
def: "A secretion that is part of a exocrine pancreas [Automatically generated definition]." [OBOL:automatic]
synonym: "exocrine pancreas secretion" EXACT [OBOL:automatic]
synonym: "pancreatic exocrine secretion" EXACT [ncithesaurus:Pancreatic_Exocrine_Secretion]
synonym: "pars exocrina pancreatis secretion" EXACT [OBOL:automatic]
synonym: "secretion of pars exocrina pancreatis" EXACT [OBOL:automatic]
xref: MA:0002518
xref: NCIT:C33256
xref: UMLS:C1518867 {source="ncithesaurus:Pancreatic_Exocrine_Secretion"}
is_a: UBERON:0004795 ! pancreas secretion
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: part_of UBERON:0000017 ! exocrine pancreas
relationship: part_of UBERON:0000017 ! exocrine pancreas

[Term]
id: UBERON:0004794
name: esophagus secretion
namespace: uberon
def: "A secretion that is part of a esophagus [Automatically generated definition]." [OBOL:automatic]
synonym: "esophageal secretion" EXACT [FMA:79662]
synonym: "gullet secretion" EXACT [OBOL:automatic]
synonym: "oesophagus secretion" EXACT [OBOL:automatic]
synonym: "secretion of esophagus" EXACT [OBOL:automatic]
synonym: "secretion of gullet" EXACT [OBOL:automatic]
synonym: "secretion of oesophagus" EXACT [OBOL:automatic]
xref: FMA:79662
xref: MA:0002514
xref: NCIT:C52555
xref: UMLS:C0227179 {source="ncithesaurus:Esophagus_Secretion"}
is_a: UBERON:0000456 ! secretion of exocrine gland
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001043 ! esophagus

[Term]
id: UBERON:0004795
name: pancreas secretion
namespace: uberon
def: "A secretion that is part of a pancreas [Automatically generated definition]." [OBOL:automatic]
synonym: "pancreatic secretion" EXACT [OBOL:automatic]
synonym: "secretion of pancreas" EXACT [OBOL:automatic]
xref: MA:0002516
xref: NCIT:C13270
xref: UMLS:C0030296 {source="ncithesaurus:Pancreatic_Secretion"}
is_a: UBERON:0000456 ! secretion of exocrine gland
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: part_of UBERON:0001264 ! pancreas
relationship: part_of UBERON:0001264 ! pancreas

[Term]
id: UBERON:0004797
name: blood vessel layer
namespace: uberon
def: "Any of the tissue layers that comprise a blood vessel. Examples: tunica media, tunica adventitia." [http://orcid.org/0000-0002-6601-2165]
xref: EMAPA:36296
xref: MA:0002854
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: part_of UBERON:0001981 ! blood vessel
relationship: part_of UBERON:0035965 ! wall of blood vessel
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/6/61/Blood_vessels.svg" xsd:anyURI

[Term]
id: UBERON:0004802
name: respiratory tract epithelium
namespace: uberon
def: "The pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi." [ISBN:0-683-40008-8, MGI:anna, MP:0010942]
subset: pheno_slim
synonym: "airway epithelium" RELATED [BTO:0000419]
synonym: "epithelial tissue of respiratory tract" EXACT [OBOL:automatic]
synonym: "epithelium of respiratory tract" EXACT [OBOL:automatic]
synonym: "respiratory epithelium" RELATED [BTO:0000419]
synonym: "respiratory tract epithelial tissue" EXACT [OBOL:automatic]
xref: BTO:0000419
xref: CALOHA:TS-0023
xref: EMAPA:32827
xref: MA:0001480
xref: SCTID:321764001
xref: VHOG:0000981
is_a: UBERON:0004807 ! respiratory system epithelium
is_a: UBERON:0005911 ! endo-epithelium
is_a: UBERON:0010499 ! pseudostratified ciliated columnar epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000065 ! respiratory tract
relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0000072 ! proximo-distal subdivision of respiratory tract

[Term]
id: UBERON:0004803
name: penis epithelium
namespace: uberon
def: "An epithelium that is part of a penis [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of penis" EXACT [OBOL:automatic]
synonym: "epithelium of penis" EXACT [OBOL:automatic]
synonym: "penis epithelial tissue" EXACT [OBOL:automatic]
xref: EHDAA2:0004039
xref: EMAPA:35674
xref: MA:0001742
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000989 ! penis
relationship: part_of UBERON:0000989 ! penis

[Term]
id: UBERON:0004804
name: oviduct epithelium
namespace: uberon
def: "An epithelium that is part of a oviduct [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "columnar epithelium of the fallopian tube" RELATED [BTO:0002402]
synonym: "columnar epithelium of the oviduct" RELATED [BTO:0002402]
synonym: "epithelial tissue of oviduct" EXACT [OBOL:automatic]
synonym: "epithelium of fallopian tube" EXACT [OBOL:automatic]
synonym: "epithelium of oviduct" EXACT [OBOL:automatic]
synonym: "epithelium of uterine tube" EXACT [FMA:62016]
synonym: "fallopian tube epithelium" RELATED [BTO:0002402]
synonym: "oviduct epithelial tissue" EXACT [OBOL:automatic]
xref: BTO:0002402
xref: CALOHA:TS-1316
xref: EMAPA:29043
xref: MA:0001718
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000993 ! oviduct
relationship: part_of UBERON:0003889 ! fallopian tube
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "in FMA, epithelium of uterine tube is a subclass of ciliated columnar epithelium. MA introduces subtypes: ciliated columnar and cuboidal. We map the FMA type according to its relationships, not its label" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0004805
name: seminal vesicle epithelium
namespace: uberon
def: "An epithelium that is part of a seminal vesicle [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of seminal gland" EXACT [OBOL:automatic]
synonym: "epithelial tissue of seminal vesicle" EXACT [OBOL:automatic]
synonym: "epithelium of seminal gland" EXACT [OBOL:automatic]
synonym: "epithelium of seminal vesicle" EXACT [OBOL:automatic]
synonym: "seminal gland epithelial tissue" EXACT [OBOL:automatic]
synonym: "seminal gland epithelium" EXACT [OBOL:automatic]
synonym: "seminal vesicle epithelial tissue" EXACT [OBOL:automatic]
xref: CALOHA:TS-2069
xref: EMAPA:29771
xref: MA:0001745
xref: NCIT:C49295
xref: UMLS:C1710049 {source="ncithesaurus:Seminal_Vesicle_Epithelium"}
is_a: UBERON:0004910 ! epithelium of male gonad
is_a: UBERON:0012275 ! meso-epithelium
is_a: UBERON:0034969 ! epithelial layer of duct
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000998 ! seminal vesicle
relationship: part_of UBERON:0000998 ! seminal vesicle

[Term]
id: UBERON:0004806
name: vas deferens epithelium
namespace: uberon
def: "An epithelium that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic]
synonym: "deferent duct epithelial tissue" EXACT [OBOL:automatic]
synonym: "deferent duct epithelium" EXACT [OBOL:automatic]
synonym: "ductus deferens epithelial tissue" EXACT [OBOL:automatic]
synonym: "ductus deferens epithelium" EXACT [OBOL:automatic]
synonym: "epithelial tissue of deferent duct" EXACT [OBOL:automatic]
synonym: "epithelial tissue of ductus deferens" EXACT [OBOL:automatic]
synonym: "epithelial tissue of sperm duct" EXACT [OBOL:automatic]
synonym: "epithelial tissue of vas deferen" EXACT [OBOL:automatic]
synonym: "epithelial tissue of vas deferens" EXACT [OBOL:automatic]
synonym: "epithelium of deferent duct" EXACT [OBOL:automatic]
synonym: "epithelium of ductus deferens" EXACT [OBOL:automatic]
synonym: "epithelium of sperm duct" EXACT [OBOL:automatic]
synonym: "epithelium of vas deferen" EXACT [OBOL:automatic]
synonym: "epithelium of vas deferens" EXACT [OBOL:automatic]
synonym: "sperm duct epithelial tissue" EXACT [OBOL:automatic]
synonym: "sperm duct epithelium" EXACT [OBOL:automatic]
synonym: "vas deferen epithelial tissue" EXACT [OBOL:automatic]
synonym: "vas deferen epithelium" EXACT [OBOL:automatic]
synonym: "vas deferens epithelial tissue" EXACT [OBOL:automatic]
xref: EMAPA:29274
xref: FMA:225317
xref: MA:0001749
xref: NCIT:C49315
xref: UMLS:C1710617 {source="ncithesaurus:Vas_Deferens_Epithelium"}
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0034969 ! epithelial layer of duct
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001000 ! vas deferens
relationship: part_of UBERON:0001000 ! vas deferens

[Term]
id: UBERON:0004807
name: respiratory system epithelium
namespace: uberon
def: "An epithelium that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "apparatus respiratorius epithelial tissue" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius epithelium" EXACT [OBOL:automatic]
synonym: "epithelial tissue of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "epithelial tissue of respiratory system" EXACT [OBOL:automatic]
synonym: "epithelium of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "epithelium of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory system epithelial tissue" EXACT [OBOL:automatic]
xref: CALOHA:TS-0023
xref: EMAPA:32826
xref: MA:0001823
xref: VHOG:0000981
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0004808
name: gastrointestinal system epithelium
namespace: uberon
def: "An epithelium that is part of a digestive system [Automatically generated definition]." [OBOL:automatic]
synonym: "digestive system epithelial tissue" EXACT [OBOL:automatic]
synonym: "digestive system epithelium" EXACT [OBOL:automatic]
synonym: "epithelial tissue of digestive system" EXACT [OBOL:automatic]
synonym: "epithelial tissue of gastrointestinal system" EXACT [OBOL:automatic]
synonym: "epithelium of digestive system" EXACT [OBOL:automatic]
synonym: "epithelium of gastrointestinal system" EXACT [OBOL:automatic]
synonym: "gastrointestinal system epithelial tissue" EXACT [OBOL:automatic]
xref: EMAPA:32683
xref: MA:0001520
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system
relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system

[Term]
id: UBERON:0004810
name: nephron tubule epithelium
namespace: uberon
def: "The cellular avascular layer of the renal tubule luminar surfaces." [MGI:csmith, MP:0009640]
subset: pheno_slim
synonym: "kidney tubule epithelium" EXACT [MA:0001681]
xref: BTO:0005239
xref: EMAPA:36524
xref: MA:0001681
xref: NCIT:C49276
xref: UMLS:C1709902 {source="ncithesaurus:Renal_Tubule_Epithelium"}
is_a: UBERON:0004211 ! nephron epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: adjacent_to UBERON:0000464 ! anatomical space
intersection_of: part_of UBERON:0001231 ! nephron tubule
relationship: adjacent_to UBERON:0000464 ! anatomical space
relationship: contributes_to_morphology_of UBERON:0001231 ! nephron tubule
relationship: part_of UBERON:0001231 ! nephron tubule
property_value: editor_note "See https://github.com/obophenotype/uberon/issues/1305" xsd:string

[Term]
id: UBERON:0004811
name: endometrium epithelium
namespace: uberon
def: "An epithelium that is part of an endometrium [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "endometrium epithelial tissue" EXACT [OBOL:automatic]
synonym: "epithelial tissue of endometrium" EXACT [OBOL:automatic]
synonym: "epithelium of endometrium" EXACT [OBOL:automatic]
synonym: "epithelium of tunica mucosa of endometrium" EXACT [OBOL:automatic]
synonym: "uterine epithelium" RELATED [PMID:19829370]
xref: EMAPA:35307
xref: MA:0002731
xref: SCTID:253526009
is_a: UBERON:0003350 ! epithelium of mucosa
is_a: UBERON:0006955 ! uterine epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001295 ! endometrium
relationship: part_of UBERON:0001295 ! endometrium
property_value: UBPROP:0000008 "In rodents and primates, the uterine epithelium (the endometrium) is eroded away so that maternal blood comes into direct contact with the trophoblast surface (called haemochorial)" xsd:string {source="PMID:19829370"}

[Term]
id: UBERON:0004813
name: seminiferous tubule epithelium
namespace: uberon
def: "The stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule." [MGI:csmith, MP:0011750]
subset: pheno_slim
synonym: "epithelial tissue of seminiferous tubule" EXACT [OBOL:automatic]
synonym: "epithelial tissue of seminiferous tubule of testis" EXACT [OBOL:automatic]
synonym: "epithelium of seminiferous tubule" EXACT [OBOL:automatic]
synonym: "epithelium of seminiferous tubule of testis" EXACT [OBOL:automatic]
synonym: "germinal epithelium (male)" EXACT [Wikipedia:Germinal_epithelium_(male)]
synonym: "male germinal epithelium" EXACT [Wikipedia:Germinal_epithelium_(male)]
synonym: "seminiferous epithelium" EXACT [BTO:0001811]
synonym: "seminiferous tubule epithelial tissue" EXACT [OBOL:automatic]
synonym: "testis germinal epithelium" EXACT [VHOG:0000631]
synonym: "wall of seminiferous tubule" EXACT [Wikipedia:Germinal_epithelium_(male)]
xref: BTO:0001811
xref: CALOHA:TS-0920
xref: EHDAA:8148
xref: EMAPA:35761
xref: FMA:19885
xref: GAID:401
xref: MA:0001748
xref: MESH:D012670
xref: NCIT:C49296
xref: RETIRED_EHDAA2:0002009
xref: UMLS:C0036629 {source="ncithesaurus:Seminiferous_Epithelium"}
xref: VHOG:0000631
xref: Wikipedia:Germinal_epithelium_(male)
is_a: UBERON:0001136 ! mesothelium
is_a: UBERON:0004910 ! epithelium of male gonad
is_a: UBERON:0034969 ! epithelial layer of duct
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001343 ! seminiferous tubule of testis
relationship: contributes_to_morphology_of UBERON:0001343 ! seminiferous tubule of testis
relationship: has_part CL:0000020 ! spermatogonium
relationship: has_part CL:0000216 ! Sertoli cell
relationship: part_of UBERON:0001343 ! seminiferous tubule of testis

[Term]
id: UBERON:0004815
name: lower respiratory tract epithelium
namespace: uberon
def: "An epithelium that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of lower respiratory tract" EXACT [OBOL:automatic]
synonym: "epithelium of lower respiratory tract" EXACT [OBOL:automatic]
synonym: "lower respiratory tract epithelial tissue" EXACT [OBOL:automatic]
xref: EMAPA:37549 {source="MA:th"}
xref: MA:0001481
is_a: UBERON:0004802 ! respiratory tract epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001558 ! lower respiratory tract
relationship: part_of UBERON:0001558 ! lower respiratory tract

[Term]
id: UBERON:0004819
name: kidney epithelium
namespace: uberon
def: "The cellular avascular layer of the kidney luminar surfaces." [MGI:csmith, MP:0004967]
subset: pheno_slim
synonym: "epithelial tissue of kidney" EXACT [OBOL:automatic]
synonym: "epithelium of kidney" EXACT [OBOL:automatic]
synonym: "kidney epithelial tissue" EXACT [OBOL:automatic]
synonym: "renal epithelium" RELATED [EMAPA:35457]
xref: BTO:0000059
xref: CALOHA:TS-0505
xref: EMAPA:35457
xref: MA:0002846
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0002113 ! kidney
relationship: contributes_to_morphology_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0002113 ! kidney

[Term]
id: UBERON:0004820
name: bile duct epithelium
namespace: uberon
def: "Any epithelium that lines one of the bile ducts." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "biliary duct epithelium" EXACT [OBOL:automatic]
synonym: "epithelium of bile duct" EXACT [OBOL:automatic]
synonym: "epithelium of biliary duct" EXACT [OBOL:automatic]
xref: BTO:0000417
xref: MA:0001629
xref: NCIT:C43616
xref: UMLS:C1711208 {source="ncithesaurus:Bile_Duct_Epithelium"}
is_a: UBERON:0005911 ! endo-epithelium
is_a: UBERON:0034932 ! epithelium of biliary system
is_a: UBERON:0034969 ! epithelial layer of duct
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0002394 ! bile duct
relationship: has_part CL:1000488 ! cholangiocyte
relationship: part_of UBERON:0002394 ! bile duct
property_value: UBPROP:0000001 "The irregularly shaped proliferating bile ducts are lined by normal cuboidal epithelium." xsd:string {source="BTO:0000417"}

[Term]
id: UBERON:0004822
name: extrahepatic bile duct epithelium
namespace: uberon
def: "An epithelium that is part of a extrahepatic bile duct [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of extrahepatic bile duct" EXACT [OBOL:automatic]
synonym: "epithelium of extrahepatic bile duct" EXACT [OBOL:automatic]
synonym: "extrahepatic bile duct epithelial tissue" EXACT [OBOL:automatic]
xref: EHDAA2:0000742
xref: EHDAA:3051
xref: MA:0002661
xref: NCIT:C43618
xref: UMLS:C1711347 {source="ncithesaurus:Extrahepatic_Bile_Duct_Epithelium"}
is_a: UBERON:0004820 ! bile duct epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0003703 ! extrahepatic bile duct
relationship: part_of UBERON:0003703 ! extrahepatic bile duct

[Term]
id: UBERON:0004823
name: intrahepatic bile duct epithelium
namespace: uberon
def: "An epithelium that is part of a intrahepatic bile duct [Automatically generated definition]." [OBOL:automatic]
synonym: "epithelial tissue of intrahepatic bile duct" EXACT [OBOL:automatic]
synonym: "epithelium of intrahepatic bile duct" EXACT [OBOL:automatic]
synonym: "intrahepatic bile duct epithelial tissue" EXACT [OBOL:automatic]
xref: EHDAA2:0000743
xref: EHDAA:3053
xref: MA:0002662
xref: NCIT:C43617
xref: UMLS:C1708552 {source="ncithesaurus:Intrahepatic_Bile_Duct_Epithelium"}
is_a: UBERON:0004820 ! bile duct epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0003704 ! intrahepatic bile duct
relationship: part_of UBERON:0003704 ! intrahepatic bile duct

[Term]
id: UBERON:0004829
name: urethra skeletal muscle tissue
namespace: uberon
def: "A portion of skeletal muscle tissue that is part of a urethra [Automatically generated definition]." [OBOL:automatic]
synonym: "skeletal muscle of urethra" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of urethra" EXACT [OBOL:automatic]
synonym: "urethra skeletal muscle" RELATED [MA:0001690]
synonym: "urethra skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "urethral skeletal muscle" RELATED [MA:0001690]
xref: EMAPA:37788 {source="MA:th"}
xref: MA:0001690
is_a: UBERON:0001134 ! skeletal muscle tissue
intersection_of: UBERON:0001134 ! skeletal muscle tissue
intersection_of: part_of UBERON:0000057 ! urethra
relationship: part_of UBERON:0003829 ! urethra muscle tissue

[Term]
id: UBERON:0004830
name: respiratory system skeletal muscle
namespace: uberon
def: "A portion of skeletal muscle tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
synonym: "respiratory system skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "skeletal muscle of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "skeletal muscle of respiratory system" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of respiratory system" EXACT [OBOL:automatic]
xref: EMAPA:37583 {source="MA:th"}
xref: MA:0001829
is_a: UBERON:0001134 ! skeletal muscle tissue
intersection_of: UBERON:0001134 ! skeletal muscle tissue
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0004831
name: esophagus skeletal muscle
namespace: uberon
def: "A portion of skeletal muscle tissue that is part of a esophagus [Automatically generated definition]." [OBOL:automatic]
comment: Most muscle tissue lining the digestive tract is smooth, but part of the externa of the esophagus is skeletal
synonym: "esophagus skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "skeletal muscle of esophagus" EXACT [OBOL:automatic]
xref: EMAPA:36523
xref: MA:0001572
is_a: UBERON:0003898 ! skeletal muscle tissue of trunk
intersection_of: UBERON:0001134 ! skeletal muscle tissue
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0003832 ! esophagus muscle

[Term]
id: UBERON:0004832
name: anal region skeletal muscle
namespace: uberon
def: "A portion of skeletal muscle tissue that is part of an anal region [Automatically generated definition]." [OBOL:automatic]
synonym: "anal part of perineum skeletal muscle" EXACT [OBOL:automatic]
synonym: "anal part of perineum skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "anal region skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "anal triangle skeletal muscle" EXACT [OBOL:automatic]
synonym: "anal triangle skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "skeletal muscle of anal part of perineum" EXACT [OBOL:automatic]
synonym: "skeletal muscle of anal region" EXACT [OBOL:automatic]
synonym: "skeletal muscle of anal triangle" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of anal part of perineum" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of anal region" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of anal triangle" EXACT [OBOL:automatic]
xref: EMAPA:37393 {source="MA:th"}
xref: MA:0001530
is_a: UBERON:0001134 ! skeletal muscle tissue
intersection_of: UBERON:0001134 ! skeletal muscle tissue
intersection_of: part_of UBERON:0001353 ! anal region
relationship: part_of UBERON:0001353 ! anal region

[Term]
id: UBERON:0004833
name: lip skeletal muscle
namespace: uberon
def: "A portion of skeletal muscle tissue that is part of a lip [Automatically generated definition]." [OBOL:automatic]
synonym: "lip skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "skeletal muscle of lip" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue of lip" EXACT [OBOL:automatic]
xref: EMAPA:37642 {source="MA:th"}
xref: MA:0001578
is_a: UBERON:0001134 ! skeletal muscle tissue
intersection_of: UBERON:0001134 ! skeletal muscle tissue
intersection_of: part_of UBERON:0001833 ! lip
relationship: part_of UBERON:0001833 ! lip
property_value: editor_note "this class is derived from MA. Consider re-modeling this as being a muscle that acts on the lips. See: Wikipedia:Lip#Muscles_acting_on_the_lips" xsd:string

[Term]
id: UBERON:0004834
name: hepatic duct smooth muscle
namespace: uberon
def: "Smooth muscle tissue in all or part of a hepatic duct." [http://orcid.org/0000-0002-6601-2165]
xref: EMAPA:37598 {source="MA:th"}
xref: MA:0001640
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0005171 ! hepatic duct
relationship: part_of UBERON:0005171 ! hepatic duct

[Term]
id: UBERON:0004835
name: epididymis smooth muscle
namespace: uberon
def: "A portion of smooth muscle tissue that is part of a epididymis [Automatically generated definition]." [OBOL:automatic]
synonym: "epididymis involuntary muscle" EXACT [OBOL:automatic]
synonym: "epididymis non-striated muscle" EXACT [OBOL:automatic]
synonym: "epididymis smooth muscle tissue" EXACT [OBOL:automatic]
synonym: "involuntary muscle of epididymis" EXACT [OBOL:automatic]
synonym: "non-striated muscle of epididymis" EXACT [OBOL:automatic]
synonym: "smooth muscle of epididymis" EXACT [OBOL:automatic]
synonym: "smooth muscle tissue of epididymis" EXACT [OBOL:automatic]
xref: EMAPA:30747
xref: MA:0001736
is_a: UBERON:0001135 ! smooth muscle tissue
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001301 ! epididymis
relationship: part_of UBERON:0001301 ! epididymis

[Term]
id: UBERON:0004848
name: respiratory system arterial endothelium
namespace: uberon
def: "An endothelium of artery that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "apparatus respiratorius arterial endothelium" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius artery endothelium" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius endothelium of artery" EXACT [OBOL:automatic]
synonym: "arterial endothelium of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "arterial endothelium of respiratory system" EXACT [OBOL:automatic]
synonym: "artery endothelium of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "artery endothelium of respiratory system" EXACT [OBOL:automatic]
synonym: "endothelium of artery of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "endothelium of artery of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory system artery endothelium" EXACT [OBOL:automatic]
synonym: "respiratory system endothelium of artery" EXACT [OBOL:automatic]
xref: EMAPA:37566 {source="MA:th"}
xref: MA:0001801
is_a: UBERON:0001917 ! endothelium of artery
is_a: UBERON:0004702 ! respiratory system blood vessel endothelium
intersection_of: UBERON:0001917 ! endothelium of artery
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0003469 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! respiratory system artery
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004849
name: respiratory system venous endothelium
namespace: uberon
def: "An endothelium of vein that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "apparatus respiratorius endothelium of vein" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius vein endothelium" EXACT [OBOL:automatic]
synonym: "apparatus respiratorius venous endothelium" EXACT [OBOL:automatic]
synonym: "endothelium of vein of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "endothelium of vein of respiratory system" EXACT [OBOL:automatic]
synonym: "respiratory system endothelium of vein" EXACT [OBOL:automatic]
synonym: "respiratory system vein endothelium" EXACT [OBOL:automatic]
synonym: "vein endothelium of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "vein endothelium of respiratory system" EXACT [OBOL:automatic]
synonym: "venous endothelium of apparatus respiratorius" EXACT [OBOL:automatic]
synonym: "venous endothelium of respiratory system" EXACT [OBOL:automatic]
xref: EMAPA:37585 {source="MA:th"}
xref: MA:0001811
is_a: UBERON:0001919 ! endothelium of vein
is_a: UBERON:0004702 ! respiratory system blood vessel endothelium
intersection_of: UBERON:0001919 ! endothelium of vein
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0003476 ! respiratory system venous blood vessel
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004851
name: aorta endothelium
namespace: uberon
def: "The thin layer of flat cells that line the aorta and form a barrier between circulating blood in the lumen and the rest of the vessel wall." [MGI:csmith, MP:0009864]
subset: efo_slim
subset: pheno_slim
synonym: "adult aorta endothelium" EXACT [OBOL:automatic]
synonym: "aortic endothelium" RELATED [BTO:0000394]
synonym: "endothelium of adult aorta" EXACT [OBOL:automatic]
synonym: "endothelium of aorta" EXACT [OBOL:automatic]
synonym: "endothelium of trunk of aortic tree" EXACT [OBOL:automatic]
synonym: "endothelium of trunk of systemic arterial tree" EXACT [OBOL:automatic]
synonym: "trunk of aortic tree endothelium" EXACT [OBOL:automatic]
synonym: "trunk of systemic arterial tree endothelium" EXACT [OBOL:automatic]
xref: BTO:0000394
xref: CALOHA:TS-0047
xref: EFO:0002597
xref: EMAPA:35134
xref: MA:0000701
xref: NCIT:C49190
xref: UMLS:C1706824 {source="ncithesaurus:Aorta_Endothelium"}
is_a: UBERON:0004638 ! blood vessel endothelium
is_a: UBERON:0004700 ! arterial system endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0000947 ! aorta
relationship: part_of UBERON:0000947 ! aorta

[Term]
id: UBERON:0004852
name: cardiovascular system endothelium
namespace: uberon
def: "An endothelium that is part of the cardiovascular system." [https://orcid.org/0000-0002-6601-2165]
subset: vertebrate_core
synonym: "endothelia" RELATED OMO:0003004 [ZFA:0001639]
synonym: "vascular endothelia" RELATED OMO:0003004 [XAO:0000356]
xref: BTO:0001853
xref: EMAPA:35201
xref: GAID:519
xref: MA:0000717
xref: MESH:D004730
xref: NCIT:C13053
xref: TAO:0002171
xref: UMLS:C0014261 {source="ncithesaurus:Vascular_Endothelium"}
xref: VHOG:0001217
xref: XAO:0000356
xref: ZFA:0001639
is_a: UBERON:0001986 ! endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0004535 ! cardiovascular system
relationship: part_of UBERON:0004535 ! cardiovascular system
property_value: editor_note "consider merging with 'endothelium'" xsd:string
property_value: UBPROP:0000003 "Vertebrates and a very few invertebrates such as squids have evolved a secondary epithelium, the endothelium, that lines their blood vessels.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001217", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.207", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0004854
name: gastrointestinal system mesentery
namespace: uberon
def: "A mesentery that is part of a digestive system [Automatically generated definition]." [OBOL:automatic]
subset: pheno_slim
synonym: "digestive system mesentery" EXACT [OBOL:automatic]
synonym: "mesentery of digestive system" EXACT [OBOL:automatic]
synonym: "mesentery of gastrointestinal system" EXACT [OBOL:automatic]
xref: EMAPA:37068 {source="MA:th"}
xref: MA:0001900
is_a: UBERON:0002095 ! mesentery
is_a: UBERON:0004782 ! gastrointestinal system serosa
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system

[Term]
id: UBERON:0004857
name: skeletal muscle connective tissue
namespace: uberon
def: "A connective tissue that surrounds a skeletal muscle tissue." [OBOL:automatic]
synonym: "connective tissue of skeletal muscle" EXACT [OBOL:automatic]
synonym: "connective tissue of skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of skeletal muscle" EXACT [OBOL:automatic]
synonym: "portion of connective tissue of skeletal muscle tissue" EXACT [OBOL:automatic]
synonym: "skeletal muscle interstitial tissue" RELATED [MA:0002868]
synonym: "skeletal muscle interstitum" RELATED [MA:0002868]
synonym: "skeletal muscle portion of connective tissue" EXACT [OBOL:automatic]
synonym: "skeletal muscle textus connectivus" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue connective tissue" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue portion of connective tissue" EXACT [OBOL:automatic]
synonym: "skeletal muscle tissue textus connectivus" EXACT [OBOL:automatic]
synonym: "textus connectivus of skeletal muscle" EXACT [OBOL:automatic]
synonym: "textus connectivus of skeletal muscle tissue" EXACT [OBOL:automatic]
xref: EMAPA:37743 {source="MA:th"}
xref: MA:0002868
is_a: UBERON:0002384 ! connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: surrounds UBERON:0001134 ! skeletal muscle tissue
relationship: surrounds UBERON:0001134 ! skeletal muscle tissue

[Term]
id: UBERON:0004859
name: eye gland
namespace: uberon
def: "A gland that is part of a eye. The eye is a compound unit which depending on the species may consist of an eyeballs plus associated ducts and integumentary structures. Eye glands therefore include the various types of lacrimal gland, the various types of apocrine and sebaceous glands associated with the eyelid." [http://orcid.org/0000-0002-6601-2165]
comment: Examples: harderian gland, accessory lacrimal gland, gland of Moll, gland of Zeis, nictitating membrane glands
subset: organ_slim
synonym: "eye-associated gland" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "gland of eye" EXACT [OBOL:automatic]
xref: EMAPA:35334
xref: MA:0000267
is_a: UBERON:0002530 ! gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0000970 ! eye
relationship: part_of UBERON:0000970 ! eye

[Term]
id: UBERON:0004864
name: vasculature of retina
namespace: uberon
def: "A vasculature that is part of a retina [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
subset: pheno_slim
synonym: "retina vasculature" EXACT [GO:0061298]
synonym: "retina vasculature of camera-type eye" EXACT [GO:0061298]
synonym: "retinal blood vessels" EXACT [FMA:76552]
synonym: "retinal blood vessels set" EXACT [FMA:76552]
synonym: "retinal vasculature" EXACT [OBOL:automatic]
synonym: "set of blood vessels of retina" EXACT [OBOL:automatic]
synonym: "set of retinal blood vessels" EXACT [FMA:76552]
synonym: "vasa sanguinea retinae" EXACT OMO:0003011 [FMA:76552, FMA:TA]
xref: FMA:76552
xref: MESH:D012171
xref: XAO:0004153
is_a: UBERON:0002203 ! vasculature of eye
is_a: UBERON:0036302 ! vasculature of central nervous system plus retina
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0000966 ! retina
relationship: part_of UBERON:0000966 ! retina
property_value: RO:0002161 NCBITaxon:8782 {source="PMID:21622558", source="PMID:2772405", submitter="michaelerice"}
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004867
name: orbital cavity
namespace: uberon
def: "Anatomical cavity bounded by the orbital region of the cranium and forming the location of some or all of the eye." [http://orcid.org/0000-0002-6601-2165]
synonym: "orbit" RELATED [AAO:0000343]
xref: AAO:0000343
xref: FMA:84961
xref: SCTID:280541000
xref: Wikipedia:Orbit_(anatomy)
xref: ZFA:0005558
is_a: UBERON:0002553 ! anatomical cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0001697 ! orbit of skull
relationship: luminal_space_of UBERON:0001697 ! orbit of skull
relationship: part_of UBERON:0001697 ! orbit of skull
property_value: UBPROP:0000012 "note that the AAO and ZFA class is a cavity" xsd:string {external_ontology="AAO", seeAlso="https://github.com/obophenotype/uberon/issues/462"}

[Term]
id: UBERON:0004871
name: somatic layer of lateral plate mesoderm
namespace: uberon
def: "Layer of lateral plate mesoderm that forms the future body wall - underlies the ectoderm[WP]." [Wikipedia:Lateral_plate_mesoderm#Division_into_layers]
subset: pheno_slim
synonym: "outer layer of lateral plate mesoderm" EXACT []
synonym: "parietal mesoderm" RELATED [ISBN:9780878932504]
synonym: "somatic mesoderm" RELATED [BILA:0000047]
xref: AAO:0011100
xref: BILA:0000047
xref: FMA:295570
xref: Wikipedia:Lateral_plate_mesoderm#Division_into_layers
xref: XAO:0000271
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0003081 ! lateral plate mesoderm
property_value: editor_note "check BILA" xsd:string

[Term]
id: UBERON:0004872
name: splanchnic layer of lateral plate mesoderm
namespace: uberon
def: "Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]." [Wikipedia:Lateral_plate_mesoderm#Division_into_layers]
subset: pheno_slim
synonym: "inner layer of lateral plate mesoderm" EXACT []
synonym: "splanchnic mesoderm" RELATED [ISBN:9780878932504]
synonym: "visceral mesoderm" BROAD [BILA:0000044, http://www.drugs.com/dict/visceral-mesoderm.html, http://www.stedmans.com/]
xref: AAO:0011102
xref: BILA:0000044
xref: FMA:295568
xref: Wikipedia:Lateral_plate_mesoderm#Division_into_layers
xref: XAO:0000276
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0003081 ! lateral plate mesoderm
property_value: UBPROP:0000012 "We group the BILA class here. Considering adding more general class for metazoa grouping cardiogenic successors" xsd:string {external_ontology="BILA"}

[Term]
id: UBERON:0004873
name: splanchnopleure
namespace: uberon
def: "A structure created during embryogenesis when the lateral mesoderm splits into two layers - the inner (or splanchnic) layer adheres to the endoderm, and with it forms the splanchnopleure[WP]." [Wikipedia:Splanchnopleure]
synonym: "ventral splanchnic mesoderm" RELATED [Wikipedia:Intraembryonic_coelom]
xref: EHDAA2:0001903
xref: EHDAA:383
xref: EMAPA:16181
xref: FMA:295564
xref: NCIT:C34303
xref: UMLS:C1519472 {source="ncithesaurus:Splanchnopleure"}
xref: VHOG:0000558
xref: Wikipedia:Splanchnopleure
is_a: UBERON:0002050 ! embryonic structure
relationship: overlaps UBERON:0000925 ! endoderm
relationship: part_of UBERON:0003081 {source="EHDAA2"} ! lateral plate mesoderm
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png" xsd:anyURI
property_value: editor_note "TODO - check relationship to LPM" xsd:string

[Term]
id: UBERON:0004874
name: somatopleure
namespace: uberon
def: "A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]." [Wikipedia:Somatopleure]
xref: EHDAA2:0001847
xref: EHDAA:381
xref: EMAPA:16180
xref: FMA:295566
xref: NCIT:C34301
xref: UMLS:C1519423 {source="ncithesaurus:Somatopleure"}
xref: VHOG:0000557
xref: Wikipedia:Somatopleure
is_a: UBERON:0002050 ! embryonic structure
relationship: overlaps UBERON:0000924 ! ectoderm
relationship: part_of UBERON:0003081 {source="EHDAA2"} ! lateral plate mesoderm
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png" xsd:anyURI
property_value: UBPROP:0000011 "Gives rise to the paired appendages in jawed vertebrates. a persistent somatopleure through the redistribution and expansion of the lateral plate mesoderm is a synapomorphy for gnathostomes and a critical step in generating a novel developmental module with dramatic evolutionary potentia (Tulenko et al. 2012) http://burkelab.research.wesleyan.edu/current-projects/lamprey/" xsd:string
property_value: UBPROP:0000012 "sources differ as to whether this is part-of or develops-from the LPM" xsd:string

[Term]
id: UBERON:0004875
name: nephrogenic cord
namespace: uberon
def: "A portion of the urogenital ridge which is the source of much of the urinary system[WP]." [Wikipedia:Nephrogenic_cord]
comment: part_of or develops_from urogenital ridge?
synonym: "chorda nephrogenica" RELATED OMO:0003011 [Wikipedia:Nephrogenic_cord]
xref: FMA:72168
xref: NCIT:C34219
xref: SCTID:361405003
xref: UMLS:C1283944 {source="ncithesaurus:Nephrogenic_Cord"}
xref: Wikipedia:Nephrogenic_cord
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0004876 ! urogenital fold

[Term]
id: UBERON:0004876
name: urogenital fold
namespace: uberon
def: "One of of the pair of folds derived from the cloacal folds which give rise to a portion of the external genitalia; in male embryos they close over the urethral plate and fuse to form the spongy (penile) urethra and ventral aspect of the penis, not including the glans; failure of fusion of the urethral folds leads to hypospadias; in female embryos they fuse only anterior to the anus and form the labia minora[MP]." [MP:0011835, MP:anna, Wikipedia:Urogenital_folds]
subset: pheno_slim
synonym: "urethral fold" EXACT [EMAPA:30888]
synonym: "urogenital fold" EXACT [EHDAA2:0004022, MP:0011835]
synonym: "urogenital ridge" RELATED INCONSISTENT [MP:0011835]
xref: EHDAA2:0004022
xref: EMAPA:30888
xref: FMA:321919
xref: Wikipedia:Urogenital_folds
is_a: UBERON:0006598 ! presumptive structure
relationship: develops_from UBERON:0003064 {source="Wikipedia"} ! intermediate mesoderm
relationship: develops_from UBERON:0012292 {source="EHDAA2"} ! embryonic cloacal fold
relationship: has_potential_to_develop_into UBERON:0004176 ! external genitalia
relationship: part_of UBERON:0009196 {source="EHDAA2"} ! indifferent external genitalia
property_value: UBPROP:0000013 "Less commonly, urogenital fold refers to the fold in the mesonephros which is the precursor of e.g. the suspensory ligament of the ovary. This is the case in older versions of Gray's anatomy[WP]" xsd:string

[Term]
id: UBERON:0004880
name: chordamesoderm
namespace: uberon
def: "The central region of trunk mesoderm. This tissue forms the notochord." [https://orcid.org/0000-0002-6601-2165]
subset: efo_slim
subset: pheno_slim
synonym: "axial chorda mesoderm" EXACT [ZFA:0000091]
synonym: "chorda mesoderm" EXACT []
synonym: "dorsal mesoderm" EXACT [https://github.com/obophenotype/uberon/wiki/The-neural-crest]
synonym: "presumptive notochord" EXACT [ZFA:0000091]
xref: AAO:0000478
xref: EFO:0003426
xref: TAO:0000091
xref: ZFA:0000091
is_a: UBERON:0002050 ! embryonic structure
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
relationship: part_of UBERON:0003068 ! axial mesoderm
property_value: UBPROP:0000001 "Notochord rudiment[ZFIN:ZDB-PUB-961014-576]." xsd:string {source="ZFIN:ZDB-PUB-961014-576"}
property_value: UBPROP:0000012 "WP treats this as synonym of axial mesoderm. Induces neural tube. Gilbert: contains an anterior head process and the notochord." xsd:string

[Term]
id: UBERON:0004883
name: lung mesenchyme
namespace: uberon
def: "The mass of tissue made up of mesenchymal cells in the lung." [GO:0060484]
subset: human_reference_atlas
subset: pheno_slim
synonym: "lung-associated mesenchyme" EXACT [GO:0060484]
synonym: "mesenchyme of lung" EXACT [OBOL:automatic]
synonym: "pulmonary mesenchyme" EXACT [GO:0060484]
xref: EMAPA:32866
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0002048 ! lung
relationship: develops_from UBERON:0003081 ! lateral plate mesoderm
relationship: part_of UBERON:0002048 ! lung
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004902
name: urogenital sinus epithelium
namespace: uberon
def: "The fetal urogenital sinus (from which the prostate derives) is a simple cylinder of stratified basal epithelium, surrounded by mesenchyme and positioned between the embryonic bladder and pelvic urethra." [PMID:18977204]
synonym: "epithelium of urogenital sinus" EXACT [OBOL:automatic]
synonym: "UGE" EXACT [PMID:18977204]
xref: EHDAA2:0004061
xref: EMAPA:31509
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0009846 ! embryonic cloacal epithelium
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000164 ! primitive urogenital sinus
relationship: develops_from UBERON:0009846 {source="EHDAA2"} ! embryonic cloacal epithelium
relationship: part_of UBERON:0000164 ! primitive urogenital sinus
property_value: UBPROP:0000012 "we follow EHDAA2 in dividing the UGS into epithelium and lumen" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0004904
name: neuron projection bundle connecting eye with brain
namespace: uberon
def: "A neuron projection bundle that connects the retina or its analog in the eye with the brain. This includes the vertebrate optic nerve (not truly a nerve) as well as analogous structures such as the Bolwig nerve in Drosophila." [http://orcid.org/0000-0002-6601-2165]
comment: for the vertebrate-specific structure, see UBERON:0000941 (cranial nerve II)
subset: grouping_class
subset: human_reference_atlas
subset: pheno_slim
synonym: "optic nerve" BROAD [BTO:0000966]
synonym: "optic nerve (generic)" EXACT []
xref: BTO:0000966
xref: EV:0100351
xref: FBbt:00001956 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: TADS:0000232
is_a: UBERON:0000122 ! neuron projection bundle
intersection_of: UBERON:0000122 ! neuron projection bundle
intersection_of: extends_fibers_into UBERON:0000955 ! brain
intersection_of: extends_fibers_into UBERON:0005388 ! photoreceptor array
relationship: extends_fibers_into UBERON:0000955 ! brain
relationship: extends_fibers_into UBERON:0005388 ! photoreceptor array
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0002104 ! visual system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004905
name: articulation
namespace: uberon
def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "joint" NARROW []
xref: FBbt:00005811 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0034921 ! multi organ part structure
relationship: part_of UBERON:0004770 ! articular system

[Term]
id: UBERON:0004906
name: ectodermal part of digestive tract
namespace: uberon
def: "A portion of the gut that is derived from ectoderm." [GO:0007439]
synonym: "ectodermal gut" EXACT []
synonym: "gut ectoderm" EXACT [EMAPA:32930]
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0004921 ! subdivision of digestive tract
intersection_of: UBERON:0004921 ! subdivision of digestive tract
intersection_of: develops_from UBERON:0000924 ! ectoderm
intersection_of: part_of UBERON:0001555 ! digestive tract

[Term]
id: UBERON:0004907
name: lower digestive tract
namespace: uberon
def: "The region of the digestive tract extending from the beginning of the intestines to the anus[GO - gut definition]." [Wikipedia:Alimentary_canal#Upper_gastrointestinal_tract]
subset: uberon_slim
synonym: "gut" BROAD [GO:0048565]
synonym: "lower gastrointestinal tract" EXACT []
synonym: "lower GI tract" EXACT []
xref: FMA:49179
xref: galen:LowerGastrointestinalTract
xref: NCIT:C33010
xref: SCTID:279973004
xref: UMLS:C0226875 {source="ncithesaurus:Lower_Gastrointestinal_Tract"}
xref: Wikipedia:Alimentary_canal#Upper_gastrointestinal_tract
is_a: UBERON:0004921 ! subdivision of digestive tract
relationship: develops_from UBERON:0001046 ! hindgut
relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system
property_value: UBPROP:0000012 "MA class was moved from here. See https://github.com/obophenotype/uberon/issues/509" xsd:string {external_ontology="MA"}
property_value: UBPROP:0000012 "WP: small intestine, large intestine, anus. Anal canal not part of LGIT according to FMA, but anus is considered part of LGIT according to WP. Duodenum overlaps both U/L" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0004908
name: upper digestive tract
namespace: uberon
def: "The region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum." [Wikipedia:Alimentary_canal#Upper_gastrointestinal_tract]
subset: uberon_slim
synonym: "upper gastrointestinal tract" EXACT []
synonym: "upper GI tract" EXACT []
xref: FMA:49177
xref: galen:UpperGastrointestinalTract
xref: NCIT:C33837
xref: SCTID:181244000
xref: UMLS:C0226874 {source="ncithesaurus:Upper_Gastrointestinal_Tract"}
xref: Wikipedia:Alimentary_canal#Upper_gastrointestinal_tract
is_a: UBERON:0004921 ! subdivision of digestive tract
relationship: develops_from UBERON:0001041 ! foregut
property_value: UBPROP:0000012 "WP: small intestine, large intestine, anus. Anal canal not part of LGIT according to FMA, but anus is considered part of LGIT according to WP. Duodenum overlaps both U/L. In Galen, entire GI tract excludes esophagus" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0004909
name: epithelium of gonad
namespace: uberon
def: "An epithelium surrounding a gonad." [OBOL:automatic]
synonym: "gonad epithelium" EXACT [OBOL:automatic]
synonym: "gonadal epithelium" EXACT [OBOL:automatic]
synonym: "gonadal sheath" RELATED [FBbt:00004859]
xref: EHDAA:4032
xref: EHDAA:5931
xref: NCIT:C32676
xref: UMLS:C1517534 {source="ncithesaurus:Germinal_Epithelium"}
is_a: UBERON:0000483 ! epithelium
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000991 ! gonad
relationship: part_of UBERON:0000991 ! gonad
property_value: editor_note "after reasoning this should subsume the more specific germinal epithelium classes. We include the fly structure here although it is not clear if the sheath is an epithelium or a multi-tissue structure that includes epithelium as parts" xsd:string

[Term]
id: UBERON:0004910
name: epithelium of male gonad
namespace: uberon
def: "An epithelium surrounding a testis." [OBOL:automatic]
synonym: "testis epithelium" EXACT [OBOL:automatic]
xref: BTO:0001364
xref: EMAPA:17973
is_a: UBERON:0004909 ! epithelium of gonad
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000473 ! testis
relationship: part_of UBERON:0000473 ! testis
property_value: editor_note "after reasoning this should subsume the more specific germinal epithelium classes. We include the fly structure here although it is not clear if the sheath is an epithelium or a multi-tissue structure that includes epithelium as parts" xsd:string

[Term]
id: UBERON:0004911
name: epithelium of female gonad
namespace: uberon
def: "An epithelium surrounding an ovary." [OBOL:automatic]
synonym: "ovarian epithelium" EXACT [OBOL:automatic]
synonym: "ovarian sheath" NARROW SENSU [FBbt:00004896]
synonym: "ovary epithelium" EXACT [OBOL:automatic]
xref: BTO:0003661
is_a: UBERON:0004909 ! epithelium of gonad
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000992 ! ovary
relationship: part_of UBERON:0000992 ! ovary
property_value: editor_note "after reasoning this should subsume the more specific germinal epithelium classes. We include the fly structure here although it is not clear if the sheath is an epithelium or a multi-tissue structure that includes epithelium as parts" xsd:string

[Term]
id: UBERON:0004912
name: biliary bud
namespace: uberon
synonym: "hepatic diverticulum" RELATED [EMAPA:16561]
xref: EHDAA2:0000171
xref: EMAPA:16561
xref: EMAPA_RETIRED:16565
xref: VHOG:0001351
is_a: UBERON:0004185 ! endodermal part of digestive tract
is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac
is_a: UBERON:0009497 ! epithelium of foregut-midgut junction
is_a: UBERON:0009854 ! digestive tract diverticulum
relationship: develops_from UBERON:0004161 {source="EHDAA2-modified"} ! septum transversum
relationship: part_of UBERON:0002423 {source="EHDAA2"} ! hepatobiliary system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4f/Gray1088.png" xsd:anyURI

[Term]
id: UBERON:0004913
name: hepatopancreatic ampulla
namespace: uberon
def: "A dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct." [Wikipedia:Ampulla_of_Vater]
subset: human_reference_atlas
subset: vertebrate_core
synonym: "ampulla biliaropancreatica" EXACT OMO:0003011 [FMA:15076, FMA:TA]
synonym: "ampulla hepatopancreatica" RELATED OMO:0003011 [Wikipedia:Ampulla_of_Vater]
synonym: "ampulla of bile duct" EXACT [FMA:15076]
synonym: "ampulla of Vater" EXACT []
synonym: "ampulla Vaterii" RELATED OMO:0003011 [Wikipedia:Ampulla_of_Vater]
synonym: "biliaropancreatic ampulla" EXACT []
synonym: "papilla duodeni major" RELATED [ZFA:0005167]
synonym: "papilla Vateri" EXACT [ZFA:0005167]
synonym: "Vater's ampulla" EXACT []
xref: CALOHA:TS-2348
xref: FMA:15076
xref: GAID:283
xref: galen:AmpullaOfVater
xref: MESH:D014670
xref: NCIT:C13011
xref: SCTID:362200007
xref: TAO:0005167
xref: UMLS:C0042425 {source="ncithesaurus:Ampulla_of_Vater"}
xref: Wikipedia:Ampulla_of_Vater
xref: ZFA:0005167
is_a: UBERON:0002394 ! bile duct
intersection_of: UBERON:0000058 ! duct
intersection_of: part_of UBERON:0001174 ! common bile duct
intersection_of: part_of UBERON:0004914 ! duodenal papilla
relationship: part_of UBERON:0001174 ! common bile duct
relationship: part_of UBERON:0004914 ! duodenal papilla
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Biliary_system_new.svg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Ampulla formed by the union of the pancreatic duct and the common bile duct where they enter the intestine.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005167", ontology="TAO", source="ZFIN:ZDB-PUB-070212-11", source="ZFIN:ZDB-PUB-080414-12"}

[Term]
id: UBERON:0004914
name: duodenal papilla
namespace: uberon
def: "One of the two small elevations on the mucosa of the duodenum, the major at the entrance of the conjoined pancreatic and common bile ducts and the minor at the entrance of the accessory pancreatic duct." [http://medical-dictionary.thefreedictionary.com/duodenal+papilla]
synonym: "papilla duodenalis" EXACT []
synonym: "papilla duodeni" RELATED OMO:0003011 [Wikipedia:Major_duodenal_papilla]
synonym: "papilla of duodenum" EXACT []
xref: EMAPA:18662
xref: FMA:15953
xref: MA:0003107
xref: NCIT:C119578
xref: SCTID:245389007
is_a: UBERON:0034944 ! zone of organ
relationship: part_of UBERON:0000320 ! duodenal mucosa
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/43/Gray1057.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Small_Intestine.glb" xsd:anyURI

[Term]
id: UBERON:0004915
name: sphincter of hepatopancreatic ampulla
namespace: uberon
def: "Muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through the ampulla of Vater into the second part of the duodenum. Relaxed by the hormone Cholecystokinin (CCK) via vasoactive intestinal polypeptide (VIP).[WP]." [Wikipedia:Sphincter_of_ampulla]
subset: human_reference_atlas
synonym: "hepatopancreatic ampullary sphincter" EXACT [FMA:15077]
synonym: "musculus sphincter ampullae" EXACT [FMA:15077]
synonym: "musculus sphincter ampullae hepatopancreatica" EXACT OMO:0003011 [FMA:15077, FMA:TA]
synonym: "Oddi's sphincter" EXACT []
synonym: "sphincter of ampulla of vater" EXACT [FMA:15077]
synonym: "sphincter of Oddi" EXACT []
xref: EMAPA:18663
xref: FMA:15077
xref: GAID:285
xref: MESH:D009803
xref: NCIT:C13065
xref: SCTID:181271000
xref: UMLS:C0028872 {source="ncithesaurus:Sphincter_of_Oddi"}
xref: Wikipedia:Sphincter_of_ampulla
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0011185 ! gastrointestinal sphincter
intersection_of: UBERON:0004590 ! sphincter muscle
intersection_of: part_of UBERON:0004913 ! hepatopancreatic ampulla
relationship: part_of UBERON:0004913 ! hepatopancreatic ampulla
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/43/Gray1057.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004916
name: anal sphincter
namespace: uberon
def: "A sphincter muscle that is part of a anal region." [OBOL:automatic]
synonym: "anal region sphincter" EXACT []
synonym: "sphincter analia" EXACT []
xref: EMAPA:36052
is_a: UBERON:0004590 ! sphincter muscle
intersection_of: UBERON:0004590 ! sphincter muscle
intersection_of: part_of UBERON:0001353 ! anal region
relationship: capable_of_part_of GO:0030421 ! defecation
relationship: part_of UBERON:0001353 ! anal region

[Term]
id: UBERON:0004917
name: urethral sphincter
namespace: uberon
def: "A sphincter muscle surrounding the urethra." [Wikipedia:Urethral_sphincter]
synonym: "sphincter muscle of urethra" EXACT []
synonym: "sphincter of urethra" EXACT []
synonym: "sphincter urethrae" EXACT []
synonym: "urethral sphincter muscle" EXACT []
xref: EMAPA:37789 {source="MA:th"}
xref: MA:0002650
xref: SCTID:277855007
xref: SCTID:277857004
xref: Wikipedia:Urethral_sphincter
is_a: UBERON:0003829 ! urethra muscle tissue
is_a: UBERON:0004590 ! sphincter muscle
intersection_of: UBERON:0004590 ! sphincter muscle
intersection_of: part_of UBERON:0000057 ! urethra

[Term]
id: UBERON:0004921
name: subdivision of digestive tract
namespace: uberon
def: "A proximal-distal subdivision of the digestive tract." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: non_informative
synonym: "alimentary system subdivision" RELATED [FMA:71131]
synonym: "gut section" RELATED [FBbt:00100315]
synonym: "intestinal tract" RELATED []
synonym: "segment of intestinal tract" RELATED []
synonym: "subdivision of alimentary system" RELATED [FMA:71131]
xref: FBbt:00100315 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:71131
is_a: UBERON:0013522 ! subdivision of tube
intersection_of: UBERON:0013522 ! subdivision of tube
intersection_of: subdivision_of UBERON:0001555 ! digestive tract
relationship: part_of UBERON:0001555 ! digestive tract
relationship: subdivision_of UBERON:0001555 ! digestive tract
property_value: curator_notes "intended to denote both embryonic and adult structures. Note the FMA grouping here is not quite correct." xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004923
name: organ component layer
namespace: uberon
def: "A part of a wall of an organ that forms a layer." [http://orcid.org/0000-0002-6601-2165]
subset: upper_level
xref: FMA:82485
is_a: UBERON:0000064 ! organ part
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000060 ! anatomical wall

[Term]
id: UBERON:0004924
name: submucosa of pharynx
namespace: uberon
def: "The tissue underlying the tunica mucosa of the pharynx." [BTO:0002113]
synonym: "pharyngeal submucosa" EXACT [FMA:75144]
synonym: "pharyngobasilar fascia" RELATED []
synonym: "pharynx submucosa" EXACT [OBOL:automatic]
synonym: "submucous coat of pharynx" RELATED [BTO:0002113]
synonym: "submucous layer of pharynx" RELATED [BTO:0002113]
synonym: "tela submucosa pharyngea" EXACT OMO:0003011 [FMA:75144, FMA:TA]
synonym: "tela submucosa pharyngis" EXACT OMO:0003011 [BTO:0002113]
xref: BTO:0002113
xref: FMA:75144
xref: SCTID:19594009
is_a: UBERON:0004777 ! respiratory system submucosa
is_a: UBERON:0018257 ! submucosa of digestive tract
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001042 ! chordate pharynx
relationship: part_of UBERON:0001042 ! chordate pharynx

[Term]
id: UBERON:0004926
name: submucosa of cystic duct
namespace: uberon
def: "A submucosa that is part of a cystic duct [Automatically generated definition]." [OBOL:automatic]
synonym: "cystic duct submucosa" EXACT [OBOL:automatic]
synonym: "cystic ductal submucosa" EXACT [FMA:18013]
xref: FMA:18013
is_a: UBERON:0004938 ! submucosa of biliary tree
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001152 ! cystic duct
relationship: part_of UBERON:0001152 ! cystic duct

[Term]
id: UBERON:0004932
name: submucosa of sigmoid colon
namespace: uberon
def: "A submucosa that is part of a sigmoid colon [Automatically generated definition]." [OBOL:automatic]
synonym: "sigmoid colon submucosa" EXACT [OBOL:automatic]
xref: FMA:15027
is_a: UBERON:0003331 ! submucosa of colon
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001159 ! sigmoid colon
relationship: part_of UBERON:0001159 ! sigmoid colon

[Term]
id: UBERON:0004934
name: submucosa of body of stomach
namespace: uberon
def: "A submucosa that is part of a body of stomach [Automatically generated definition]." [OBOL:automatic]
synonym: "body of stomach submucosa" EXACT [OBOL:automatic]
synonym: "corpus gastricum (ventriculare) submucosa" EXACT [OBOL:automatic]
synonym: "gastric body submucosa" EXACT [OBOL:automatic]
synonym: "stomach body submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of corpus gastricum (ventriculare)" EXACT [OBOL:automatic]
synonym: "submucosa of gastric body" EXACT [OBOL:automatic]
synonym: "submucosa of stomach body" EXACT [OBOL:automatic]
xref: FMA:17059
is_a: UBERON:0001200 ! submucosa of stomach
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001161 ! body of stomach
relationship: part_of UBERON:0001161 ! body of stomach

[Term]
id: UBERON:0004936
name: submucosa of pyloric antrum
namespace: uberon
def: "A submucosa that is part of a pyloric antrum [Automatically generated definition]." [OBOL:automatic]
synonym: "antrum of stomach submucosa" EXACT [OBOL:automatic]
synonym: "pyloric antrum submucosa" EXACT [OBOL:automatic]
synonym: "stomach pyloric antrum submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of antrum of stomach" EXACT [OBOL:automatic]
synonym: "submucosa of stomach pyloric antrum" EXACT [OBOL:automatic]
xref: FMA:17060
is_a: UBERON:0004937 ! submucosa of pylorus
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001165 ! pyloric antrum
relationship: part_of UBERON:0001165 ! pyloric antrum

[Term]
id: UBERON:0004937
name: submucosa of pylorus
namespace: uberon
def: "A submucosa that is part of a pylorus [Automatically generated definition]." [OBOL:automatic]
synonym: "pyloric part of stomach submucosa" EXACT [OBOL:automatic]
synonym: "pyloric submucosa" EXACT []
synonym: "pylorus submucosa" EXACT [FMA:17462, OBOL:automatic]
synonym: "stomach pyloric region submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of pyloric part of stomach" EXACT [OBOL:automatic]
synonym: "submucosa of stomach pyloric region" EXACT [OBOL:automatic]
xref: EMAPA:27201
xref: FMA:17462
is_a: UBERON:0001200 ! submucosa of stomach
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001166 ! pylorus
relationship: part_of UBERON:0001166 ! pylorus

[Term]
id: UBERON:0004938
name: submucosa of biliary tree
namespace: uberon
def: "A submucosa that is part of a biliary tree [Automatically generated definition]." [OBOL:automatic]
synonym: "biliary tract submucosa" EXACT [OBOL:automatic]
synonym: "biliary tree submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of biliary tract" EXACT [OBOL:automatic]
xref: FMA:18009
is_a: UBERON:0000009 ! submucosa
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001173 ! biliary tree
relationship: part_of UBERON:0001173 ! biliary tree

[Term]
id: UBERON:0004939
name: submucosa of common bile duct
namespace: uberon
def: "A submucosa that is part of a common bile duct [Automatically generated definition]." [OBOL:automatic]
synonym: "common bile duct submucosa" EXACT [OBOL:automatic]
synonym: "common bile ductal submucosa" EXACT [FMA:18011]
synonym: "ductus choledochus (biliaris) submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of ductus choledochus (biliaris)" EXACT [OBOL:automatic]
xref: FMA:18011
is_a: UBERON:0004938 ! submucosa of biliary tree
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001174 ! common bile duct
relationship: part_of UBERON:0001174 ! common bile duct

[Term]
id: UBERON:0004940
name: submucosa of common hepatic duct
namespace: uberon
def: "A submucosa that is part of a common hepatic duct [Automatically generated definition]." [OBOL:automatic]
synonym: "common hepatic duct submucosa" EXACT [OBOL:automatic]
synonym: "common hepatic ductal submucosa" EXACT [FMA:18014]
synonym: "hepatic duct submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of hepatic duct" EXACT [OBOL:automatic]
xref: FMA:18014
is_a: UBERON:0004938 ! submucosa of biliary tree
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001175 ! common hepatic duct
relationship: part_of UBERON:0001175 ! common hepatic duct

[Term]
id: UBERON:0004941
name: submucosa of right hepatic duct
namespace: uberon
def: "A submucosa that is part of a right hepatic duct [Automatically generated definition]." [OBOL:automatic]
synonym: "right hepatic duct submucosa" EXACT [OBOL:automatic]
synonym: "right hepatic ductal submucosa" EXACT [FMA:18015]
xref: FMA:18015
is_a: UBERON:0004938 ! submucosa of biliary tree
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001176 ! right hepatic duct
relationship: part_of UBERON:0001176 ! right hepatic duct

[Term]
id: UBERON:0004942
name: submucosa of left hepatic duct
namespace: uberon
def: "A submucosa that is part of a left hepatic duct [Automatically generated definition]." [OBOL:automatic]
synonym: "left hepatic duct submucosa" EXACT [OBOL:automatic]
synonym: "left hepatic ductal submucosa" EXACT [FMA:18017]
xref: FMA:18017
is_a: UBERON:0004938 ! submucosa of biliary tree
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001177 ! left hepatic duct
relationship: part_of UBERON:0001177 ! left hepatic duct

[Term]
id: UBERON:0004943
name: submucosa of urinary bladder
namespace: uberon
def: "The submucous layer of the wall of the urinary bladder." [BTO:0002117]
subset: human_reference_atlas
synonym: "bladder submucosa" EXACT [OBOL:automatic]
synonym: "submucosa of bladder" EXACT [OBOL:automatic]
synonym: "submucous layer of urinary bladder" RELATED [BTO:0002117]
synonym: "tela submucosa (vesica urinaria)" EXACT OMO:0003011 [FMA:15929, FMA:TA]
synonym: "tela submucosa vesicae" EXACT OMO:0003011 [FMA:15929, FMA:TA]
synonym: "tela submucosa vesicae urinariae" EXACT [BTO:0002117]
synonym: "urinary bladder submucosa" EXACT [OBOL:automatic]
xref: BTO:0002117
xref: EMAPA:32275
xref: FMA:15929
xref: SCTID:88384001
is_a: UBERON:0000009 ! submucosa
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001255 ! urinary bladder
relationship: part_of UBERON:0001256 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of urinary bladder
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0004980
name: mucosa of ureter
namespace: uberon
def: "A mucosa that is part of a ureter [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of organ of ureter" EXACT [OBOL:automatic]
synonym: "mucosal layer of ureter" EXACT [FMA:15894]
synonym: "mucous membrane of ureter" EXACT [OBOL:automatic]
synonym: "organ mucosa of ureter" EXACT [OBOL:automatic]
synonym: "tunica mucosa (ureter)" EXACT [FMA:15894]
synonym: "tunica mucosa ureteris" EXACT OMO:0003011 [FMA:15894, FMA:TA]
synonym: "ureter mucosa" EXACT [OBOL:automatic]
synonym: "ureter mucosa of organ" EXACT [OBOL:automatic]
synonym: "ureter mucous membrane" EXACT [OBOL:automatic]
synonym: "ureter organ mucosa" EXACT [OBOL:automatic]
synonym: "ureteral mucosa" EXACT [FMA:15894]
synonym: "ureteric mucosa" EXACT [FMA:15894]
xref: FMA:15894
xref: galen:MucousMembraneOfUreter
xref: SCTID:40476001
is_a: UBERON:0000344 ! mucosa
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000056 ! ureter
relationship: part_of UBERON:0009916 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of ureter

[Term]
id: UBERON:0004984
name: mucosa of seminal vesicle
namespace: uberon
def: "A mucosa that is part of a seminal vesicle [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of organ of seminal gland" EXACT [OBOL:automatic]
synonym: "mucosa of organ of seminal vesicle" EXACT [OBOL:automatic]
synonym: "mucosa of seminal gland" EXACT [OBOL:automatic]
synonym: "mucous membrane of seminal gland" EXACT [OBOL:automatic]
synonym: "mucous membrane of seminal vesicle" EXACT [OBOL:automatic]
synonym: "organ mucosa of seminal gland" EXACT [OBOL:automatic]
synonym: "organ mucosa of seminal vesicle" EXACT [OBOL:automatic]
synonym: "seminal gland mucosa" EXACT [OBOL:automatic]
synonym: "seminal gland mucosa of organ" EXACT [OBOL:automatic]
synonym: "seminal gland mucous membrane" EXACT [OBOL:automatic]
synonym: "seminal gland organ mucosa" EXACT [OBOL:automatic]
synonym: "seminal vesicle mucosa" EXACT [OBOL:automatic]
synonym: "seminal vesicle mucosa of organ" EXACT [OBOL:automatic]
synonym: "seminal vesicle mucous membrane" EXACT [OBOL:automatic]
synonym: "seminal vesicle organ mucosa" EXACT [OBOL:automatic]
synonym: "tunica mucosa glandulae vesiculosae" EXACT OMO:0003011 [FMA:19405, FMA:TA]
xref: FMA:19405
xref: SCTID:252260007
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0019042 ! reproductive system mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000998 ! seminal vesicle
relationship: part_of UBERON:0000998 ! seminal vesicle

[Term]
id: UBERON:0004985
name: mucosa of ejaculatory duct
namespace: uberon
def: "A mucosa that is part of a ejaculatory duct [Automatically generated definition]." [OBOL:automatic]
synonym: "ejaculatory duct mucosa" EXACT [OBOL:automatic]
synonym: "ejaculatory duct mucosa of organ" EXACT [OBOL:automatic]
synonym: "ejaculatory duct mucous membrane" EXACT [OBOL:automatic]
synonym: "ejaculatory duct organ mucosa" EXACT [OBOL:automatic]
synonym: "ejaculatory ductal mucosa" EXACT [FMA:19373]
synonym: "mucosa of organ of ejaculatory duct" EXACT [OBOL:automatic]
synonym: "mucous membrane of ejaculatory duct" EXACT [OBOL:automatic]
synonym: "organ mucosa of ejaculatory duct" EXACT [OBOL:automatic]
xref: FMA:19373
is_a: UBERON:0019042 ! reproductive system mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000999 ! ejaculatory duct
relationship: part_of UBERON:0000999 ! ejaculatory duct

[Term]
id: UBERON:0004986
name: mucosa of deferent duct
namespace: uberon
def: "A mucosa that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic]
synonym: "deferent duct mucosa" EXACT [OBOL:automatic]
synonym: "deferent duct mucosa of organ" EXACT [OBOL:automatic]
synonym: "deferent duct mucous membrane" EXACT [OBOL:automatic]
synonym: "deferent duct organ mucosa" EXACT [OBOL:automatic]
synonym: "deferent ductal mucosa" EXACT [FMA:19240]
synonym: "ductus deferens mucosa" EXACT [OBOL:automatic]
synonym: "ductus deferens mucosa of organ" EXACT [OBOL:automatic]
synonym: "ductus deferens mucous membrane" EXACT [OBOL:automatic]
synonym: "ductus deferens organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of ductus deferens" EXACT [OBOL:automatic]
synonym: "mucosa of organ of deferent duct" EXACT [OBOL:automatic]
synonym: "mucosa of organ of ductus deferens" EXACT [OBOL:automatic]
synonym: "mucosa of organ of sperm duct" EXACT [OBOL:automatic]
synonym: "mucosa of organ of vas deferen" EXACT [OBOL:automatic]
synonym: "mucosa of organ of vas deferens" EXACT [OBOL:automatic]
synonym: "mucosa of sperm duct" EXACT [OBOL:automatic]
synonym: "mucosa of vas deferen" EXACT [OBOL:automatic]
synonym: "mucosa of vas deferens" EXACT [OBOL:automatic]
synonym: "mucous membrane of deferent duct" EXACT [OBOL:automatic]
synonym: "mucous membrane of ductus deferens" EXACT [OBOL:automatic]
synonym: "mucous membrane of sperm duct" EXACT [OBOL:automatic]
synonym: "mucous membrane of vas deferen" EXACT [OBOL:automatic]
synonym: "mucous membrane of vas deferens" EXACT [OBOL:automatic]
synonym: "organ mucosa of deferent duct" EXACT [OBOL:automatic]
synonym: "organ mucosa of ductus deferens" EXACT [OBOL:automatic]
synonym: "organ mucosa of sperm duct" EXACT [OBOL:automatic]
synonym: "organ mucosa of vas deferen" EXACT [OBOL:automatic]
synonym: "organ mucosa of vas deferens" EXACT [OBOL:automatic]
synonym: "sperm duct mucosa" EXACT [OBOL:automatic]
synonym: "sperm duct mucosa of organ" EXACT [OBOL:automatic]
synonym: "sperm duct mucous membrane" EXACT [OBOL:automatic]
synonym: "sperm duct organ mucosa" EXACT [OBOL:automatic]
synonym: "tunica mucosa (ductus deferens)" EXACT [FMA:19240]
synonym: "tunica mucosa ductus deferentis" EXACT OMO:0003011 [FMA:19240, FMA:TA]
synonym: "vas deferen mucosa" EXACT [OBOL:automatic]
synonym: "vas deferen mucosa of organ" EXACT [OBOL:automatic]
synonym: "vas deferen mucous membrane" EXACT [OBOL:automatic]
synonym: "vas deferen organ mucosa" EXACT [OBOL:automatic]
synonym: "vas deferens mucosa" EXACT [OBOL:automatic]
synonym: "vas deferens mucosa of organ" EXACT [OBOL:automatic]
synonym: "vas deferens mucous membrane" EXACT [OBOL:automatic]
synonym: "vas deferens organ mucosa" EXACT [OBOL:automatic]
xref: FMA:19240
xref: SCTID:299626000
is_a: UBERON:0019042 ! reproductive system mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001000 ! vas deferens
relationship: part_of UBERON:0001000 ! vas deferens

[Term]
id: UBERON:0004988
name: mucosa of cystic duct
namespace: uberon
def: "A mucosa that is part of a cystic duct [Automatically generated definition]." [OBOL:automatic]
synonym: "cystic duct mucosa" EXACT [OBOL:automatic]
synonym: "cystic duct mucosa of organ" EXACT [OBOL:automatic]
synonym: "cystic duct mucous membrane" EXACT [OBOL:automatic]
synonym: "cystic duct organ mucosa" EXACT [OBOL:automatic]
synonym: "cystic ductal mucosa" EXACT [FMA:14690]
synonym: "mucosa of organ of cystic duct" EXACT [OBOL:automatic]
synonym: "mucous membrane of cystic duct" EXACT [OBOL:automatic]
synonym: "organ mucosa of cystic duct" EXACT [OBOL:automatic]
xref: FMA:14690
is_a: UBERON:0004999 ! mucosa of biliary tree
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001152 ! cystic duct
relationship: part_of UBERON:0001152 ! cystic duct

[Term]
id: UBERON:0004993
name: mucosa of sigmoid colon
namespace: uberon
def: "A mucosa that is part of a sigmoid colon [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of organ of sigmoid colon" EXACT [OBOL:automatic]
synonym: "mucous membrane of sigmoid colon" EXACT [OBOL:automatic]
synonym: "organ mucosa of sigmoid colon" EXACT [OBOL:automatic]
synonym: "sigmoid colon mucosa" EXACT [OBOL:automatic]
synonym: "sigmoid colon mucosa of organ" EXACT [OBOL:automatic]
synonym: "sigmoid colon mucous membrane" EXACT [OBOL:automatic]
synonym: "sigmoid colon organ mucosa" EXACT [OBOL:automatic]
xref: FMA:15026
is_a: UBERON:0000317 ! colonic mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001159 ! sigmoid colon
relationship: part_of UBERON:0001159 ! sigmoid colon

[Term]
id: UBERON:0004995
name: mucosa of body of stomach
namespace: uberon
def: "A mucosa that is part of a body of stomach [Automatically generated definition]." [OBOL:automatic]
synonym: "body of stomach mucosa" EXACT [OBOL:automatic]
synonym: "body of stomach mucosa of organ" EXACT [OBOL:automatic]
synonym: "body of stomach mucous membrane" EXACT [OBOL:automatic]
synonym: "body of stomach organ mucosa" EXACT [OBOL:automatic]
synonym: "corpus gastricum (ventriculare) mucosa" EXACT [OBOL:automatic]
synonym: "corpus gastricum (ventriculare) mucosa of organ" EXACT [OBOL:automatic]
synonym: "corpus gastricum (ventriculare) mucous membrane" EXACT [OBOL:automatic]
synonym: "corpus gastricum (ventriculare) organ mucosa" EXACT [OBOL:automatic]
synonym: "gastric body mucosa" EXACT [OBOL:automatic]
synonym: "gastric body mucosa of organ" EXACT [OBOL:automatic]
synonym: "gastric body mucous membrane" EXACT [OBOL:automatic]
synonym: "gastric body organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of corpus gastricum (ventriculare)" EXACT [OBOL:automatic]
synonym: "mucosa of gastric body" EXACT [OBOL:automatic]
synonym: "mucosa of organ of body of stomach" EXACT [OBOL:automatic]
synonym: "mucosa of organ of corpus gastricum (ventriculare)" EXACT [OBOL:automatic]
synonym: "mucosa of organ of gastric body" EXACT [OBOL:automatic]
synonym: "mucosa of organ of stomach body" EXACT [OBOL:automatic]
synonym: "mucosa of stomach body" EXACT [OBOL:automatic]
synonym: "mucous membrane of body of stomach" EXACT [OBOL:automatic]
synonym: "mucous membrane of corpus gastricum (ventriculare)" EXACT [OBOL:automatic]
synonym: "mucous membrane of gastric body" EXACT [OBOL:automatic]
synonym: "mucous membrane of stomach body" EXACT [OBOL:automatic]
synonym: "organ mucosa of body of stomach" EXACT [OBOL:automatic]
synonym: "organ mucosa of corpus gastricum (ventriculare)" EXACT [OBOL:automatic]
synonym: "organ mucosa of gastric body" EXACT [OBOL:automatic]
synonym: "organ mucosa of stomach body" EXACT [OBOL:automatic]
synonym: "stomach body mucosa" EXACT [OBOL:automatic]
synonym: "stomach body mucosa of organ" EXACT [OBOL:automatic]
synonym: "stomach body mucous membrane" EXACT [OBOL:automatic]
synonym: "stomach body organ mucosa" EXACT [OBOL:automatic]
xref: FMA:17054
is_a: UBERON:0001199 ! mucosa of stomach
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001161 ! body of stomach
relationship: part_of UBERON:0001161 ! body of stomach

[Term]
id: UBERON:0004997
name: mucosa of pyloric antrum
namespace: uberon
def: "A mucosa that is part of a pyloric antrum [Automatically generated definition]." [OBOL:automatic]
synonym: "antral mucosa" EXACT [BTO:0004107]
synonym: "antrum of stomach mucosa" EXACT [OBOL:automatic]
synonym: "antrum of stomach mucosa of organ" EXACT [OBOL:automatic]
synonym: "antrum of stomach mucous membrane" EXACT [OBOL:automatic]
synonym: "antrum of stomach organ mucosa" EXACT [OBOL:automatic]
synonym: "gastric antrum mucosa" RELATED [BTO:0004107]
synonym: "mucosa of antrum of stomach" EXACT [OBOL:automatic]
synonym: "mucosa of organ of antrum of stomach" EXACT [OBOL:automatic]
synonym: "mucosa of organ of pyloric antrum" EXACT [OBOL:automatic]
synonym: "mucosa of organ of stomach pyloric antrum" EXACT [OBOL:automatic]
synonym: "mucosa of stomach pyloric antrum" EXACT [OBOL:automatic]
synonym: "mucous membrane of antrum of stomach" EXACT [OBOL:automatic]
synonym: "mucous membrane of pyloric antrum" EXACT [OBOL:automatic]
synonym: "mucous membrane of stomach pyloric antrum" EXACT [OBOL:automatic]
synonym: "organ mucosa of antrum of stomach" EXACT [OBOL:automatic]
synonym: "organ mucosa of pyloric antrum" EXACT [OBOL:automatic]
synonym: "organ mucosa of stomach pyloric antrum" EXACT [OBOL:automatic]
synonym: "pyloric antrum mucosa" EXACT [OBOL:automatic]
synonym: "pyloric antrum mucosa of organ" EXACT [OBOL:automatic]
synonym: "pyloric antrum mucous membrane" EXACT [OBOL:automatic]
synonym: "pyloric antrum organ mucosa" EXACT [OBOL:automatic]
synonym: "stomach pyloric antrum mucosa" EXACT [OBOL:automatic]
synonym: "stomach pyloric antrum mucosa of organ" EXACT [OBOL:automatic]
synonym: "stomach pyloric antrum mucous membrane" EXACT [OBOL:automatic]
synonym: "stomach pyloric antrum organ mucosa" EXACT [OBOL:automatic]
xref: BTO:0004107
xref: FMA:17055
is_a: UBERON:0004998 ! mucosa of pylorus
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001165 ! pyloric antrum
relationship: part_of UBERON:0001165 ! pyloric antrum
relationship: part_of UBERON:0004998 {source="BTO"} ! mucosa of pylorus

[Term]
id: UBERON:0004998
name: mucosa of pylorus
namespace: uberon
def: "A mucosa that is part of a pylorus [Automatically generated definition]." [OBOL:automatic]
synonym: "antropyloric mucosa" RELATED [BTO:0002984]
synonym: "mucosa of organ of pyloric part of stomach" EXACT [OBOL:automatic]
synonym: "mucosa of organ of pylorus" EXACT [OBOL:automatic]
synonym: "mucosa of organ of stomach pyloric region" EXACT [OBOL:automatic]
synonym: "mucosa of pyloric part of stomach" EXACT [OBOL:automatic]
synonym: "mucosa of stomach pyloric region" EXACT [OBOL:automatic]
synonym: "mucous membrane of pyloric part of stomach" EXACT [OBOL:automatic]
synonym: "mucous membrane of pylorus" EXACT [OBOL:automatic]
synonym: "mucous membrane of stomach pyloric region" EXACT [OBOL:automatic]
synonym: "organ mucosa of pyloric part of stomach" EXACT [OBOL:automatic]
synonym: "organ mucosa of pylorus" EXACT [OBOL:automatic]
synonym: "organ mucosa of stomach pyloric region" EXACT [OBOL:automatic]
synonym: "pyloric part of stomach mucosa" EXACT [OBOL:automatic]
synonym: "pyloric part of stomach mucosa of organ" EXACT [OBOL:automatic]
synonym: "pyloric part of stomach mucous membrane" EXACT [OBOL:automatic]
synonym: "pyloric part of stomach organ mucosa" EXACT [OBOL:automatic]
synonym: "pylorus mucosa" EXACT [OBOL:automatic]
synonym: "pylorus mucosa of organ" EXACT [OBOL:automatic]
synonym: "pylorus mucous membrane" EXACT [OBOL:automatic]
synonym: "pylorus organ mucosa" EXACT [OBOL:automatic]
synonym: "stomach pyloric region mucosa" EXACT [OBOL:automatic]
synonym: "stomach pyloric region mucosa of organ" EXACT [OBOL:automatic]
synonym: "stomach pyloric region mucous membrane" EXACT [OBOL:automatic]
synonym: "stomach pyloric region organ mucosa" EXACT [OBOL:automatic]
xref: BTO:0004110
xref: EMAPA:27199
xref: FMA:17461
is_a: UBERON:0001199 ! mucosa of stomach
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001166 ! pylorus
relationship: part_of UBERON:0001166 ! pylorus

[Term]
id: UBERON:0004999
name: mucosa of biliary tree
namespace: uberon
def: "A mucosa that is part of a biliary tree [Automatically generated definition]." [OBOL:automatic]
synonym: "biliary tract mucosa" EXACT [OBOL:automatic]
synonym: "biliary tract mucosa of organ" EXACT [OBOL:automatic]
synonym: "biliary tract mucous membrane" EXACT [OBOL:automatic]
synonym: "biliary tract organ mucosa" EXACT [OBOL:automatic]
synonym: "biliary tree mucosa" EXACT [OBOL:automatic]
synonym: "biliary tree mucosa of organ" EXACT [OBOL:automatic]
synonym: "biliary tree mucous membrane" EXACT [OBOL:automatic]
synonym: "biliary tree organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of biliary tract" EXACT [OBOL:automatic]
synonym: "mucosa of organ of biliary tract" EXACT [OBOL:automatic]
synonym: "mucosa of organ of biliary tree" EXACT [OBOL:automatic]
synonym: "mucous membrane of biliary tract" EXACT [OBOL:automatic]
synonym: "mucous membrane of biliary tree" EXACT [OBOL:automatic]
synonym: "organ mucosa of biliary tract" EXACT [OBOL:automatic]
synonym: "organ mucosa of biliary tree" EXACT [OBOL:automatic]
xref: FMA:14695
is_a: UBERON:0000344 ! mucosa
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001173 ! biliary tree
relationship: part_of UBERON:0001173 ! biliary tree

[Term]
id: UBERON:0005000
name: mucosa of common bile duct
namespace: uberon
def: "A mucosa that is part of a common bile duct [Automatically generated definition]." [OBOL:automatic]
synonym: "common bile duct mucosa" EXACT [OBOL:automatic]
synonym: "common bile duct mucosa of organ" EXACT [OBOL:automatic]
synonym: "common bile duct mucous membrane" EXACT [OBOL:automatic]
synonym: "common bile duct organ mucosa" EXACT [OBOL:automatic]
synonym: "common bile ductal mucosa" EXACT [FMA:14688]
synonym: "ductus choledochus (biliaris) mucosa" EXACT [OBOL:automatic]
synonym: "ductus choledochus (biliaris) mucosa of organ" EXACT [OBOL:automatic]
synonym: "ductus choledochus (biliaris) mucous membrane" EXACT [OBOL:automatic]
synonym: "ductus choledochus (biliaris) organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of ductus choledochus (biliaris)" EXACT [OBOL:automatic]
synonym: "mucosa of organ of common bile duct" EXACT [OBOL:automatic]
synonym: "mucosa of organ of ductus choledochus (biliaris)" EXACT [OBOL:automatic]
synonym: "mucous membrane of common bile duct" EXACT [OBOL:automatic]
synonym: "mucous membrane of ductus choledochus (biliaris)" EXACT [OBOL:automatic]
synonym: "organ mucosa of common bile duct" EXACT [OBOL:automatic]
synonym: "organ mucosa of ductus choledochus (biliaris)" EXACT [OBOL:automatic]
xref: FMA:14688
is_a: UBERON:0004999 ! mucosa of biliary tree
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001174 ! common bile duct
relationship: part_of UBERON:0001174 ! common bile duct

[Term]
id: UBERON:0005001
name: mucosa of common hepatic duct
namespace: uberon
def: "A mucosa that is part of a common hepatic duct [Automatically generated definition]." [OBOL:automatic]
synonym: "common hepatic duct mucosa" EXACT [OBOL:automatic]
synonym: "common hepatic duct mucosa of organ" EXACT [OBOL:automatic]
synonym: "common hepatic duct mucous membrane" EXACT [OBOL:automatic]
synonym: "common hepatic duct organ mucosa" EXACT [OBOL:automatic]
synonym: "common hepatic ductal mucosa" EXACT [FMA:14691]
synonym: "hepatic duct mucosa" EXACT [OBOL:automatic]
synonym: "hepatic duct mucosa of organ" EXACT [OBOL:automatic]
synonym: "hepatic duct mucous membrane" EXACT [OBOL:automatic]
synonym: "hepatic duct organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of hepatic duct" EXACT [OBOL:automatic]
synonym: "mucosa of organ of common hepatic duct" EXACT [OBOL:automatic]
synonym: "mucosa of organ of hepatic duct" EXACT [OBOL:automatic]
synonym: "mucous membrane of common hepatic duct" EXACT [OBOL:automatic]
synonym: "mucous membrane of hepatic duct" EXACT [OBOL:automatic]
synonym: "organ mucosa of common hepatic duct" EXACT [OBOL:automatic]
synonym: "organ mucosa of hepatic duct" EXACT [OBOL:automatic]
xref: FMA:14691
is_a: UBERON:0004999 ! mucosa of biliary tree
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001175 ! common hepatic duct
relationship: part_of UBERON:0001175 ! common hepatic duct

[Term]
id: UBERON:0005002
name: mucosa of right hepatic duct
namespace: uberon
def: "A mucosa that is part of a right hepatic duct [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of organ of right hepatic duct" EXACT [OBOL:automatic]
synonym: "mucous membrane of right hepatic duct" EXACT [OBOL:automatic]
synonym: "organ mucosa of right hepatic duct" EXACT [OBOL:automatic]
synonym: "right hepatic duct mucosa" EXACT [OBOL:automatic]
synonym: "right hepatic duct mucosa of organ" EXACT [OBOL:automatic]
synonym: "right hepatic duct mucous membrane" EXACT [OBOL:automatic]
synonym: "right hepatic duct organ mucosa" EXACT [OBOL:automatic]
synonym: "right hepatic ductal mucosa" EXACT [FMA:14692]
xref: FMA:14692
is_a: UBERON:0004999 ! mucosa of biliary tree
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001176 ! right hepatic duct
relationship: part_of UBERON:0001176 ! right hepatic duct

[Term]
id: UBERON:0005003
name: mucosa of left hepatic duct
namespace: uberon
def: "A mucosa that is part of a left hepatic duct [Automatically generated definition]." [OBOL:automatic]
synonym: "left hepatic duct mucosa" EXACT [OBOL:automatic]
synonym: "left hepatic duct mucosa of organ" EXACT [OBOL:automatic]
synonym: "left hepatic duct mucous membrane" EXACT [OBOL:automatic]
synonym: "left hepatic duct organ mucosa" EXACT [OBOL:automatic]
synonym: "left hepatic ductal mucosa" EXACT [FMA:14693]
synonym: "mucosa of organ of left hepatic duct" EXACT [OBOL:automatic]
synonym: "mucous membrane of left hepatic duct" EXACT [OBOL:automatic]
synonym: "organ mucosa of left hepatic duct" EXACT [OBOL:automatic]
xref: FMA:14693
is_a: UBERON:0004999 ! mucosa of biliary tree
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001177 ! left hepatic duct
relationship: part_of UBERON:0001177 ! left hepatic duct

[Term]
id: UBERON:0005004
name: mucosa of right ureter
namespace: uberon
def: "A mucosa that is part of a right ureter [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of organ of right ureter" EXACT [OBOL:automatic]
synonym: "mucous membrane of right ureter" EXACT [OBOL:automatic]
synonym: "organ mucosa of right ureter" EXACT [OBOL:automatic]
synonym: "right ureter mucosa" EXACT [OBOL:automatic]
synonym: "right ureter mucosa of organ" EXACT [OBOL:automatic]
synonym: "right ureter mucous membrane" EXACT [OBOL:automatic]
synonym: "right ureter organ mucosa" EXACT [OBOL:automatic]
synonym: "right ureteral mucosa" EXACT [FMA:17806]
xref: FMA:17806
is_a: UBERON:0004980 ! mucosa of ureter
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001222 ! right ureter
relationship: part_of UBERON:0001222 ! right ureter

[Term]
id: UBERON:0005005
name: mucosa of left ureter
namespace: uberon
def: "A mucosa that is part of a left ureter [Automatically generated definition]." [OBOL:automatic]
subset: human_reference_atlas
synonym: "left ureter mucosa" EXACT [OBOL:automatic]
synonym: "left ureter mucosa of organ" EXACT [OBOL:automatic]
synonym: "left ureter mucous membrane" EXACT [OBOL:automatic]
synonym: "left ureter organ mucosa" EXACT [OBOL:automatic]
synonym: "left ureteral mucosa" EXACT [FMA:17807]
synonym: "mucosa of organ of left ureter" EXACT [OBOL:automatic]
synonym: "mucous membrane of left ureter" EXACT [OBOL:automatic]
synonym: "organ mucosa of left ureter" EXACT [OBOL:automatic]
xref: FMA:17807
is_a: UBERON:0004980 ! mucosa of ureter
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001223 ! left ureter
relationship: part_of UBERON:0001223 ! left ureter
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0005006
name: mucosa of renal pelvis
namespace: uberon
def: "A mucosa that is part of a renal pelvis [Automatically generated definition]." [OBOL:automatic]
synonym: "kidney pelvis mucosa" EXACT [OBOL:automatic]
synonym: "kidney pelvis mucosa of organ" EXACT [OBOL:automatic]
synonym: "kidney pelvis mucous membrane" EXACT [OBOL:automatic]
synonym: "kidney pelvis organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of kidney pelvis" EXACT [OBOL:automatic]
synonym: "mucosa of organ of kidney pelvis" EXACT [OBOL:automatic]
synonym: "mucosa of organ of pelvis of ureter" EXACT [OBOL:automatic]
synonym: "mucosa of organ of renal pelvis" EXACT [OBOL:automatic]
synonym: "mucosa of pelvis of ureter" EXACT [OBOL:automatic]
synonym: "mucous membrane of kidney pelvis" EXACT [OBOL:automatic]
synonym: "mucous membrane of pelvis of ureter" EXACT [OBOL:automatic]
synonym: "mucous membrane of renal pelvis" EXACT [OBOL:automatic]
synonym: "organ mucosa of kidney pelvis" EXACT [OBOL:automatic]
synonym: "organ mucosa of pelvis of ureter" EXACT [OBOL:automatic]
synonym: "organ mucosa of renal pelvis" EXACT [OBOL:automatic]
synonym: "pelvis of ureter mucosa" EXACT [OBOL:automatic]
synonym: "pelvis of ureter mucosa of organ" EXACT [OBOL:automatic]
synonym: "pelvis of ureter mucous membrane" EXACT [OBOL:automatic]
synonym: "pelvis of ureter organ mucosa" EXACT [OBOL:automatic]
synonym: "renal pelvic mucosa" EXACT [FMA:17931]
synonym: "renal pelvis mucosa" EXACT [OBOL:automatic]
synonym: "renal pelvis mucosa of organ" EXACT [OBOL:automatic]
synonym: "renal pelvis mucous membrane" EXACT [OBOL:automatic]
synonym: "renal pelvis organ mucosa" EXACT [OBOL:automatic]
synonym: "tunica mucosa pelvis renalis" EXACT OMO:0003011 [FMA:17931, FMA:TA]
xref: FMA:17931
xref: SCTID:243482002
is_a: UBERON:0000344 ! mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001224 ! renal pelvis
relationship: part_of UBERON:0001224 ! renal pelvis

[Term]
id: UBERON:0005011
name: mucosa of right uterine tube
namespace: uberon
def: "A mucosa that is part of a right uterine tube [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of organ of right fallopian tube" EXACT [OBOL:automatic]
synonym: "mucosa of organ of right oviduct" EXACT [OBOL:automatic]
synonym: "mucosa of organ of right uterine tube" EXACT [OBOL:automatic]
synonym: "mucosa of right fallopian tube" EXACT [OBOL:automatic]
synonym: "mucosa of right oviduct" EXACT [OBOL:automatic]
synonym: "mucous membrane of right fallopian tube" EXACT [OBOL:automatic]
synonym: "mucous membrane of right oviduct" EXACT [OBOL:automatic]
synonym: "mucous membrane of right uterine tube" EXACT [OBOL:automatic]
synonym: "organ mucosa of right fallopian tube" EXACT [OBOL:automatic]
synonym: "organ mucosa of right oviduct" EXACT [OBOL:automatic]
synonym: "organ mucosa of right uterine tube" EXACT [OBOL:automatic]
synonym: "right fallopian tube mucosa" EXACT [OBOL:automatic]
synonym: "right fallopian tube mucosa of organ" EXACT [OBOL:automatic]
synonym: "right fallopian tube mucous membrane" EXACT [OBOL:automatic]
synonym: "right fallopian tube organ mucosa" EXACT [OBOL:automatic]
synonym: "right oviduct mucosa" EXACT [OBOL:automatic]
synonym: "right oviduct mucosa of organ" EXACT [OBOL:automatic]
synonym: "right oviduct mucous membrane" EXACT [OBOL:automatic]
synonym: "right oviduct organ mucosa" EXACT [OBOL:automatic]
synonym: "right uterine tube mucosa" EXACT [OBOL:automatic]
synonym: "right uterine tube mucosa of organ" EXACT [OBOL:automatic]
synonym: "right uterine tube mucous membrane" EXACT [OBOL:automatic]
synonym: "right uterine tube organ mucosa" EXACT [OBOL:automatic]
xref: FMA:18452
is_a: UBERON:0005048 ! mucosa of uterine tube
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001302 ! right uterine tube
relationship: part_of UBERON:0001302 ! right uterine tube

[Term]
id: UBERON:0005012
name: mucosa of left uterine tube
namespace: uberon
def: "A mucosa that is part of a left uterine tube [Automatically generated definition]." [OBOL:automatic]
synonym: "left fallopian tube mucosa" EXACT [OBOL:automatic]
synonym: "left fallopian tube mucosa of organ" EXACT [OBOL:automatic]
synonym: "left fallopian tube mucous membrane" EXACT [OBOL:automatic]
synonym: "left fallopian tube organ mucosa" EXACT [OBOL:automatic]
synonym: "left oviduct mucosa" EXACT [OBOL:automatic]
synonym: "left oviduct mucosa of organ" EXACT [OBOL:automatic]
synonym: "left oviduct mucous membrane" EXACT [OBOL:automatic]
synonym: "left oviduct organ mucosa" EXACT [OBOL:automatic]
synonym: "left uterine tube mucosa" EXACT [OBOL:automatic]
synonym: "left uterine tube mucosa of organ" EXACT [OBOL:automatic]
synonym: "left uterine tube mucous membrane" EXACT [OBOL:automatic]
synonym: "left uterine tube organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of left fallopian tube" EXACT [OBOL:automatic]
synonym: "mucosa of left oviduct" EXACT [OBOL:automatic]
synonym: "mucosa of organ of left fallopian tube" EXACT [OBOL:automatic]
synonym: "mucosa of organ of left oviduct" EXACT [OBOL:automatic]
synonym: "mucosa of organ of left uterine tube" EXACT [OBOL:automatic]
synonym: "mucous membrane of left fallopian tube" EXACT [OBOL:automatic]
synonym: "mucous membrane of left oviduct" EXACT [OBOL:automatic]
synonym: "mucous membrane of left uterine tube" EXACT [OBOL:automatic]
synonym: "organ mucosa of left fallopian tube" EXACT [OBOL:automatic]
synonym: "organ mucosa of left oviduct" EXACT [OBOL:automatic]
synonym: "organ mucosa of left uterine tube" EXACT [OBOL:automatic]
xref: FMA:18453
is_a: UBERON:0005048 ! mucosa of uterine tube
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001303 ! left uterine tube
relationship: part_of UBERON:0001303 ! left uterine tube

[Term]
id: UBERON:0005013
name: mucosa of male urethra
namespace: uberon
def: "A mucosa that is part of a male urethra [Automatically generated definition]." [OBOL:automatic]
synonym: "male urethra mucosa" EXACT [OBOL:automatic]
synonym: "male urethra mucosa of organ" EXACT [OBOL:automatic]
synonym: "male urethra mucous membrane" EXACT [OBOL:automatic]
synonym: "male urethra organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of organ of male urethra" EXACT [OBOL:automatic]
synonym: "mucous membrane of male urethra" EXACT [OBOL:automatic]
synonym: "organ mucosa of male urethra" EXACT [OBOL:automatic]
xref: FMA:239937
is_a: UBERON:0012299 ! mucosa of urethra
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001333 ! male urethra
relationship: part_of UBERON:0001333 ! male urethra

[Term]
id: UBERON:0005014
name: mucosa of female urethra
namespace: uberon
def: "A mucosa that is part of a female urethra [Automatically generated definition]." [OBOL:automatic]
synonym: "female urethra mucosa" EXACT [OBOL:automatic]
synonym: "female urethra mucosa of organ" EXACT [OBOL:automatic]
synonym: "female urethra mucous membrane" EXACT [OBOL:automatic]
synonym: "female urethra organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of organ of female urethra" EXACT [OBOL:automatic]
synonym: "mucous membrane of female urethra" EXACT [OBOL:automatic]
synonym: "organ mucosa of female urethra" EXACT [OBOL:automatic]
xref: FMA:239940
is_a: UBERON:0012299 ! mucosa of urethra
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001334 ! female urethra
relationship: part_of UBERON:0001334 ! female urethra

[Term]
id: UBERON:0005031
name: mucosa of upper lip
namespace: uberon
def: "A mucosa that is part of a upper lip [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of organ of upper lip" EXACT [OBOL:automatic]
synonym: "mucous membrane of upper lip" EXACT [OBOL:automatic]
synonym: "organ mucosa of upper lip" EXACT [OBOL:automatic]
synonym: "upper labial mucosa" EXACT [UBERON:cjm]
synonym: "upper lip mucosa" EXACT [OBOL:automatic]
synonym: "upper lip mucosa of organ" EXACT [OBOL:automatic]
synonym: "upper lip mucous membrane" EXACT [OBOL:automatic]
synonym: "upper lip organ mucosa" EXACT [OBOL:automatic]
xref: FMA:59832
xref: NCIT:C12224
xref: SCTID:362088009
xref: UMLS:C0226933 {source="ncithesaurus:Mucosa_of_the_Upper_Lip"}
is_a: UBERON:0036294 ! mucosa of lip
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001834 ! upper lip
relationship: part_of UBERON:0001834 ! upper lip

[Term]
id: UBERON:0005032
name: mucosa of lower lip
namespace: uberon
def: "A mucosa that is part of a lower lip [Automatically generated definition]." [OBOL:automatic]
synonym: "lower labial mucosa" EXACT [UBERON:cjm]
synonym: "lower lip mucosa" EXACT [OBOL:automatic]
synonym: "lower lip mucosa of organ" EXACT [OBOL:automatic]
synonym: "lower lip mucous membrane" EXACT [OBOL:automatic]
synonym: "lower lip organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of organ of lower lip" EXACT [OBOL:automatic]
synonym: "mucous membrane of lower lip" EXACT [OBOL:automatic]
synonym: "organ mucosa of lower lip" EXACT [OBOL:automatic]
xref: FMA:59833
xref: NCIT:C12225
xref: SCTID:362089001
xref: UMLS:C0226939 {source="ncithesaurus:Mucosa_of_the_Lower_Lip"}
is_a: UBERON:0036294 ! mucosa of lip
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001835 ! lower lip
relationship: part_of UBERON:0001835 ! lower lip

[Term]
id: UBERON:0005033
name: mucosa of gallbladder
namespace: uberon
def: "A mucosa that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic]
synonym: "gall bladder mucosa" EXACT [OBOL:automatic]
synonym: "gall bladder mucosa of organ" EXACT [OBOL:automatic]
synonym: "gall bladder mucous membrane" EXACT [OBOL:automatic]
synonym: "gall bladder organ mucosa" EXACT [OBOL:automatic]
synonym: "gallbladder mucosa" EXACT [OBOL:automatic]
synonym: "gallbladder mucosa of organ" EXACT [OBOL:automatic]
synonym: "gallbladder mucous membrane" EXACT [OBOL:automatic]
synonym: "gallbladder organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of gall bladder" EXACT [OBOL:automatic]
synonym: "mucosa of organ of gall bladder" EXACT [OBOL:automatic]
synonym: "mucosa of organ of gallbladder" EXACT [OBOL:automatic]
synonym: "mucous membrane of gall bladder" EXACT [OBOL:automatic]
synonym: "mucous membrane of gallbladder" EXACT [OBOL:automatic]
synonym: "organ mucosa of gall bladder" EXACT [OBOL:automatic]
synonym: "organ mucosa of gallbladder" EXACT [OBOL:automatic]
synonym: "tunica mucosa (vesica biliaris)" EXACT [FMA:14662]
synonym: "tunica mucosa vesicae biliaris" EXACT OMO:0003011 [FMA:14662, FMA:TA]
xref: FMA:14662
xref: SCTID:362196002
is_a: UBERON:0000344 ! mucosa
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0002110 ! gallbladder
relationship: part_of UBERON:0002110 ! gallbladder

[Term]
id: UBERON:0005048
name: mucosa of uterine tube
namespace: uberon
def: "A mucosa that is part of a fallopian tube [Automatically generated definition]." [OBOL:automatic]
synonym: "fallopian tube mucosa" EXACT [OBOL:automatic]
synonym: "fallopian tube mucosa of organ" EXACT [OBOL:automatic]
synonym: "fallopian tube mucous membrane" EXACT [OBOL:automatic]
synonym: "fallopian tube organ mucosa" EXACT [OBOL:automatic]
synonym: "mucosa of fallopian tube" EXACT [OBOL:automatic]
synonym: "mucosa of organ of fallopian tube" EXACT [OBOL:automatic]
synonym: "mucosa of organ of uterine tube" EXACT [OBOL:automatic]
synonym: "mucosa of oviduct" EXACT [FMA:18319]
synonym: "mucous membrane of fallopian tube" EXACT [OBOL:automatic]
synonym: "mucous membrane of uterine tube" EXACT [OBOL:automatic]
synonym: "organ mucosa of fallopian tube" EXACT [OBOL:automatic]
synonym: "organ mucosa of uterine tube" EXACT [OBOL:automatic]
synonym: "tunica mucosa tubae uterinae" EXACT OMO:0003011 [FMA:18319, FMA:TA]
synonym: "uterine tubal mucosa" EXACT [FMA:18319]
synonym: "uterine tube mucosa" EXACT [OBOL:automatic]
synonym: "uterine tube mucosa of organ" EXACT [OBOL:automatic]
synonym: "uterine tube mucous membrane" EXACT [OBOL:automatic]
synonym: "uterine tube organ mucosa" EXACT [OBOL:automatic]
xref: FMA:18319
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0019042 ! reproductive system mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0003889 ! fallopian tube
relationship: part_of UBERON:0003889 ! fallopian tube

[Term]
id: UBERON:0005049
name: mucosa of infundibulum of uterine tube
namespace: uberon
def: "A mucosa that is part of a uterine tube infundibulum [Automatically generated definition]." [OBOL:automatic]
synonym: "mucosa of infundibulum of fallopian tube" EXACT [FMA:18357]
synonym: "mucosa of infundibulum of oviduct" EXACT [FMA:18357]
synonym: "mucosa of organ of uterine tube infundibulum" EXACT [OBOL:automatic]
synonym: "mucosa of uterine tube infundibulum" EXACT [OBOL:automatic]
synonym: "mucous membrane of uterine tube infundibulum" EXACT [OBOL:automatic]
synonym: "organ mucosa of uterine tube infundibulum" EXACT [OBOL:automatic]
synonym: "uterine tube infundibulum mucosa" EXACT [OBOL:automatic]
synonym: "uterine tube infundibulum mucosa of organ" EXACT [OBOL:automatic]
synonym: "uterine tube infundibulum mucous membrane" EXACT [OBOL:automatic]
synonym: "uterine tube infundibulum organ mucosa" EXACT [OBOL:automatic]
xref: FMA:18357
is_a: UBERON:0019042 ! reproductive system mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0003984 ! uterine tube infundibulum
relationship: part_of UBERON:0003984 ! uterine tube infundibulum

[Term]
id: UBERON:0005051
name: mediastinum testis
namespace: uberon
def: "The mediastinum testis is a network of fibrous connective tissue that extends from the upper to near the lower extremity of the testis, and is wider above than below. From its front and sides numerous imperfect septa (trabeculæ) are given off, which radiate toward the surface of the organ, and are attached to the tunica albuginea. They divide the interior of the organ into a number of incomplete spaces, called lobules. These are somewhat cone-shaped, being broad at their bases at the surface of the gland, and becoming narrower as they converge to the mediastinum. The mediastinum supports the rete testis and blood vessels of the testis in their passage to and from the substance of the gland[WP]." [Wikipedia:Mediastinum_testis]
synonym: "body of highmore" EXACT [FMA:19812]
synonym: "hilum of testicle" EXACT []
synonym: "mediastinum of testis" EXACT [FMA:19812]
synonym: "testis mediastinum" EXACT [FMA:19812]
xref: EMAPA:18331
xref: FMA:19812
xref: MA:0003240
xref: SCTID:362279007
xref: Wikipedia:Mediastinum_testis
is_a: UBERON:0002050 ! embryonic structure
relationship: has_part UBERON:0002384 ! connective tissue
relationship: overlaps UBERON:0003728 ! mediastinum
relationship: part_of UBERON:0000473 ! testis
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg" xsd:anyURI

[Term]
id: UBERON:0005056
name: external female genitalia
namespace: uberon
def: "An external genitalia that is part of a female reproductive system [Automatically generated definition]." [OBOL:automatic]
comment: TODO: Relabel. Make distinct organ class. See https://github.com/obophenotype/uberon/issues/547
subset: organ_slim
subset: pheno_slim
synonym: "external female genital organ" EXACT [BTO:0003100]
synonym: "external genitalia of female reproductive system" EXACT [OBOL:automatic]
synonym: "female external genitalia" EXACT [FMA:45649]
synonym: "organa genitalia feminina externa" RELATED [BTO:0003100]
xref: BTO:0003100
xref: EMAPA:30984
xref: FMA:45649
xref: galen:FemaleExternalGenitalia
xref: SCTID:362234008
is_a: UBERON:0003134 ! female reproductive organ
is_a: UBERON:0004176 ! external genitalia
intersection_of: UBERON:0004176 ! external genitalia
intersection_of: part_of UBERON:0000474 ! female reproductive system
disjoint_from: UBERON:0009196 ! indifferent external genitalia
property_value: UBPROP:0000008 "in eutherians, this is known as the vulva in and composed of the mons pubis, the labia majora and minora, the clitoris, the vestibule of the vagina and its glands, and the opening of the urethra and of the vagina [MP:0003126]" xsd:string

[Term]
id: UBERON:0005057
name: immune organ
namespace: uberon
def: "An organ that is part of a immune system [Automatically generated definition]." [OBOL:automatic]
subset: organ_slim
subset: pheno_slim
synonym: "immune system organ" EXACT []
is_a: UBERON:0000062 ! organ
intersection_of: UBERON:0000062 ! organ
intersection_of: part_of UBERON:0002405 ! immune system
relationship: part_of UBERON:0002405 ! immune system

[Term]
id: UBERON:0005058
name: hemolymphoid system gland
namespace: uberon
def: "A gland that is part of a hemolymphoid system [Automatically generated definition]." [OBOL:automatic]
subset: organ_slim
synonym: "haemolymphoid system gland" RELATED [EMAPA:18766]
synonym: "hemopoietic or lymphoid gland" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "hemopoietic or lymphoid organ" BROAD [GO:0048534]
xref: EMAPA:18766
xref: MA:0002962
is_a: UBERON:0002530 ! gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0002193 ! hemolymphoid system
relationship: part_of UBERON:0002193 ! hemolymphoid system

[Term]
id: UBERON:0005061
name: neural groove
namespace: uberon
def: "The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds." [GO:0001842, http://orcid.org/0000-0002-6601-2165, Wikipedia:Neural_groove]
xref: AAO:0011071
xref: EMAPA:35594
xref: FMA:295624
xref: NCIT:C34224
xref: neuronames:1363
xref: SCTID:361463007
xref: UMLS:C0814992 {source="ncithesaurus:Neural_Groove"}
xref: Wikipedia:Neural_groove
xref: XAO:0000248
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0003075 ! neural plate
property_value: UBPROP:0000001 "The neural groove is a shallow median groove between the neural folds of an embryo. The neural folds are two longitudinal ridges that are caused by a folding up of the ectoderm in front of the primitive streak of the developing embryo. The groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or canal, the ectodermal wall of which forms the rudiment of the nervous system. After the coalescence of the neural folds over the anterior end of the primitive streak, the blastopore no longer opens on the surface but into the closed canal of the neural tube, and thus a transitory communication, the neurenteric canal, is established between the neural tube and the primitive digestive tube. The coalescence of the neural folds occurs first in the region of the hind-brain, and from there extends forward and backward; toward the end of the third week the front opening (anterior neuropore) of the tube finally closes at the anterior end of the future brain, and forms a recess which is in contact, for a time, with the overlying ectoderm; the hinder part of the neural groove presents for a time a rhomboidal shape, and to this expanded portion the term sinus rhomboidalis has been applied. Before the neural groove is closed a ridge of ectodermal cells appears along the prominent margin of each neural fold; this is termed the neural crest or ganglion ridge, and from it the spinal and cranial nerve ganglia and the ganglia of the sympathetic nervous system are developed. By the upward growth of the mesoderm the neural tube is ultimately separated from the overlying ectoderm. The cephalic end of the neural groove exhibits several dilatations, which, when the tube is closed, assume the form of three vesicles; these constitute the three primary cerebral vesicles, and correspond respectively to the future fore-brain (prosencephalon), mid-brain (mesencephalon), and hind-brain (rhombencephalon). The walls of the vesicles are developed into the nervous tissue and neuroglia of the brain, and their cavities are modified to form its ventricles. The remainder of the tube forms the medulla spinalis or spinal cord; from its ectodermal wall the nervous and neuroglial elements of the medulla spinalis are developed while the cavity persists as the central canal[Wikipedia:Neural_groove]." xsd:string {source="Wikipedia:Neural_groove"}

[Term]
id: UBERON:0005062
name: neural fold
namespace: uberon
def: "One of the two elevated edges of the neural groove[GO,MP]." [GO:0001842, MP:0011256, Wikipedia:Neural_fold]
subset: pheno_slim
synonym: "medullary fold" EXACT [MP:0011256]
xref: EHDAA2:0001249
xref: FMA:295618
xref: NCIT:C34223
xref: neuronames:1364
xref: SCTID:361461009
xref: UMLS:C0814993 {source="ncithesaurus:Neural_Fold"}
xref: Wikipedia:Neural_fold
xref: XAO:0004087
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0005157 ! epithelial fold
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
is_a: UBERON:0015212 ! lateral structure
relationship: in_lateral_side_of UBERON:0005061 ! neural groove
relationship: part_of UBERON:0005061 ! neural groove
property_value: UBPROP:0000001 "In front of the primitive streak two longitudinal ridges, caused by a folding up of the ectoderm, make their appearance, one on either side of the middle line. These are named the neural folds; they commence some little distance behind the anterior end of the embryonic disk, where they are continuous with each other, and from there gradually extend backward, one on either side of the anterior end of the primitive streak. Also, after differentiation it turns into the neural tubes[Wikipedia:Neural_fold]." xsd:string {source="Wikipedia:Neural_fold"}

[Term]
id: UBERON:0005064
name: left ventricular trabecular myocardium
namespace: uberon
def: "Missing definition for term UBERON:0005064. Please replace it using linked reference." [GO:0003225]
is_a: UBERON:0004126 ! trabecular layer of ventricle
intersection_of: UBERON:0004126 ! trabecular layer of ventricle
intersection_of: part_of UBERON:0002084 ! heart left ventricle
relationship: part_of UBERON:0003382 {source="GO"} ! cardiac muscle of left ventricle

[Term]
id: UBERON:0005066
name: right ventricular trabecular myocardium
namespace: uberon
def: "Missing definition for term UBERON:0005066. Please replace it using linked reference." [GO:0003227]
is_a: UBERON:0004126 ! trabecular layer of ventricle
intersection_of: UBERON:0004126 ! trabecular layer of ventricle
intersection_of: part_of UBERON:0002080 ! heart right ventricle
relationship: part_of UBERON:0003381 {source="GO"} ! cardiac muscle of right ventricle

[Term]
id: UBERON:0005068
name: neural rod
namespace: uberon
def: "A solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]." [GO:0014024, ZFA:0000133]
subset: efo_slim
synonym: "neural tube rod" RELATED [GO:0014027]
xref: EFO:0003498
xref: TAO:0000133
xref: ZFA:0000133
is_a: UBERON:0016879 ! future central nervous system
relationship: develops_from UBERON:0007135 ! neural keel
property_value: UBPROP:0000001 "An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000133", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0005076
name: hindbrain-spinal cord boundary
namespace: uberon
def: "An anatomical boundary that adjacent_to a hindbrain and adjacent_to a spinal cord." [OBOL:automatic]
synonym: "hindbrain-spinal cord boundary region" EXACT []
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0007651 ! anatomical junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: adjacent_to UBERON:0002028 ! hindbrain
intersection_of: adjacent_to UBERON:0002240 ! spinal cord
relationship: adjacent_to UBERON:0002028 ! hindbrain
relationship: adjacent_to UBERON:0002240 ! spinal cord
relationship: part_of UBERON:0001017 ! central nervous system

[Term]
id: UBERON:0005080
name: metanephric ureteric bud
namespace: uberon
def: "The portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros[GO]." [GO:0035502]
is_a: UBERON:0000084 ! ureteric bud
intersection_of: UBERON:0000084 ! ureteric bud
intersection_of: has_potential_to_develop_into UBERON:0000081 ! metanephros
relationship: has_potential_to_develop_into UBERON:0000081 ! metanephros

[Term]
id: UBERON:0005081
name: ureter ureteric bud
namespace: uberon
def: "The portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter[GO]." [GO:0035503]
is_a: UBERON:0000084 ! ureteric bud
intersection_of: UBERON:0000084 ! ureteric bud
intersection_of: has_potential_to_develop_into UBERON:0000056 ! ureter
relationship: has_potential_to_develop_into UBERON:0000056 ! ureter

[Term]
id: UBERON:0005082
name: tube lumen
namespace: uberon
def: "A hole in a tube[GO]." [GO:0060609]
xref: AEO:0000078
xref: EHDAA2:0004618
xref: RETIRED_EHDAA2:0003078
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: surrounded_by UBERON:0000025 ! tube
relationship: surrounded_by UBERON:0000025 ! tube

[Term]
id: UBERON:0005085
name: ectodermal placode
namespace: uberon
def: "An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm[GO]." [GO:0060788]
synonym: "epithelial placode" RELATED [AEO:0000112]
xref: AEO:0000218
is_a: UBERON:0001048 ! primordium
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0000924 ! ectoderm
property_value: editor_note "consder adding placodal ectoderm as a distinct class? Also place placodal ectoderm as develops_from ectoderm; need to check taxon-appropriateness" xsd:string
property_value: UBPROP:0000008 "With the exception of the adenohypophysis, homologues of the nonneurogenic placodes (e.g. placodes giving rise to the teeth, hair follicles and lens), appear to be lacking in invertebrate chordates." xsd:string
property_value: UBPROP:0000012 "in GO, covers optic, otic, olfactory, mammary, hair, tooth, sebaceous - and also insect structures" xsd:string {external_ontology="GO", source="https://github.com/geneontology/go-ontology/issues/12223#issuecomment-215692347"}

[Term]
id: UBERON:0005090
name: muscle structure
namespace: uberon
def: "Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]." [GO:0061061]
synonym: "muscle" RELATED []
synonym: "muscle element" RELATED []
synonym: "musculus" EXACT [FMA:30316]
xref: EMAPA:32715
xref: FMA:30316
is_a: UBERON:0000061 ! anatomical structure
relationship: has_part CL:0000187 ! muscle cell
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: curator_notes "in some organisms such as drosophila, muscles can be single cells. This class groups together all discrete muscle elements, from multicellular muscle organs in vertebrates, to individual single-cell muscles in drisophila" xsd:string

[Term]
id: UBERON:0005092
name: right horn of sinus venosus
namespace: uberon
synonym: "sinus venosus right horn" EXACT [VHOG:0000489]
xref: EHDAA2:0001841
xref: EHDAA:484
xref: EMAPA:16239
xref: FMA:70318
xref: VHOG:0000489
is_a: UBERON:0002050 {source="FMA"} ! embryonic structure
relationship: in_right_side_of UBERON:0002063 ! sinus venosus
relationship: part_of UBERON:0002063 ! sinus venosus
property_value: UBPROP:0000003 "Three major adaptations, or 'novel cardiac components', that were not present in the ancestor chordate heart tube can be distinguished in the lower vertebrate heart: the atrium, ventricle, and possibly the muscular sinus venosus.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000489", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003 Moorman AFM, Christoffels VM, Cardiac Chamber Formation: Development, Genes, and Evolution. Physiological Reviews (2003", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005095
name: kidney rudiment
namespace: uberon
def: "Missing definition for term UBERON:0005095. Please replace it using linked reference." [GO:0072003]
synonym: "kidney anlage" RELATED [GOC:mtg_kidney_jan10]
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0007687 {source="GO"} ! kidney field
property_value: editor_note "class added for consistency with GO - consider merging with kidney mesenchyme." xsd:string

[Term]
id: UBERON:0005103
name: mesonephric epithelium
namespace: uberon
def: "An epithelium that is part of a mesonephros [Automatically generated definition]." [OBOL:automatic]
is_a: UBERON:0004819 ! kidney epithelium
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000080 ! mesonephros
relationship: part_of UBERON:0000080 ! mesonephros

[Term]
id: UBERON:0005106
name: metanephric tubule
namespace: uberon
def: "A metanephric tubule is an epithelial tube that is part of the metanephros[GO]." [GO:0072173]
xref: VHOG:0001526
is_a: UBERON:0003914 ! epithelial tube
is_a: UBERON:0005108 ! metanephric epithelium
is_a: UBERON:0006555 ! excretory tube
intersection_of: UBERON:0003914 ! epithelial tube
intersection_of: part_of UBERON:0000081 ! metanephros
property_value: UBPROP:0000003 "The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001526", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005108
name: metanephric epithelium
namespace: uberon
def: "An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure[GO]." [GO:0072207]
is_a: UBERON:0004819 ! kidney epithelium
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: part_of UBERON:0000081 ! metanephros

[Term]
id: UBERON:0005109
name: metanephric smooth muscle tissue
namespace: uberon
def: "Any smooth muscle tissue that is part of a metanephros." [GO:0072208, https://orcid.org/0000-0002-6601-2165]
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: part_of UBERON:0000081 ! metanephros

[Term]
id: UBERON:0005110
name: metanephric nephron
namespace: uberon
alt_id: UBERON:0005142
def: "A metanephric nephron is the functional unit of the metanephros[GO]." [GO:0072273]
xref: VHOG:0000719
is_a: UBERON:0001285 ! nephron
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0001285 ! nephron
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: develops_from UBERON:0003220 {source="Wikipedia", source="Wikipedia:Nephron"} ! metanephric mesenchyme
relationship: develops_from UBERON:0010535 ! primitive metanephric nephron
relationship: immediate_transformation_of UBERON:0010535 {source="Bgee:AN"} ! primitive metanephric nephron
relationship: part_of UBERON:0000081 ! metanephros
property_value: UBPROP:0000003 "The primitive form of the vertebrate nephron consists of a vascular filtration surface overlain with podocytes, a specialized coelomic cavity to receive the ultrafiltrate, and a tubule for modification to final urine. Although previously thought to be unique to the vertebrates, this design is now known to be widespread among invertebrates, including most of the protochordates, and especially their larvae.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000719", ontology="VHOG", source="DOI:10.1093/icb/34.4.542 Ruppert EE, Evolutionary Origin of the Vertebrate Nephron. Integrative and Comparative Biology (1994)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005113
name: metanephric cortex mesenchyme
namespace: uberon
xref: EHDAA2:0001140
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: develops_from UBERON:0010531 {source="EHDAA2"} ! metanephros induced blastemal cells

[Term]
id: UBERON:0005115
name: metanephric cortical collecting duct
namespace: uberon
def: "The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex[GO]." [GO:0072219]
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0004203 ! cortical collecting duct
intersection_of: UBERON:0004203 ! cortical collecting duct
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: part_of UBERON:0004737 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric collecting duct
relationship: part_of UBERON:0010533 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephros cortex

[Term]
id: UBERON:0005134
name: metanephric nephron epithelium
namespace: uberon
def: "The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros[GO]." [GO:0072243]
is_a: UBERON:0004211 ! nephron epithelium
is_a: UBERON:0005108 ! metanephric epithelium
intersection_of: UBERON:0004211 ! nephron epithelium
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: part_of UBERON:0005110 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric nephron

[Term]
id: UBERON:0005137
name: metanephric capsule
namespace: uberon
alt_id: UBERON:0005112
def: "The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage[GO]." [GO:0072213]
is_a: UBERON:0002015 ! kidney capsule
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0002015 ! kidney capsule
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: part_of UBERON:0000081 ! metanephros

[Term]
id: UBERON:0005146
name: metanephric nephron tubule
namespace: uberon
alt_id: UBERON:0005128
alt_id: UBERON:0005152
def: "A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros[GO]." [GO:0072282]
is_a: UBERON:0001231 ! nephron tubule
is_a: UBERON:0005106 ! metanephric tubule
is_a: UBERON:0005134 ! metanephric nephron epithelium
intersection_of: UBERON:0001231 ! nephron tubule
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: develops_from UBERON:0003220 {source="ISBN:9780878932504"} ! metanephric mesenchyme

[Term]
id: UBERON:0005147
name: metanephric renal vesicle
namespace: uberon
def: "The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]." [GO:0072283]
synonym: "metanephric vesicle" EXACT []
xref: EHDAA2:0001245
xref: EHDAA:9346
xref: EMAPA:27678
is_a: UBERON:0004209 ! renal vesicle
is_a: UBERON:0005108 ! metanephric epithelium
intersection_of: UBERON:0004209 ! renal vesicle
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: develops_from UBERON:0005113 {source="EHDAA2"} ! metanephric cortex mesenchyme
relationship: has_potential_to_develop_into UBERON:0005134 ! metanephric nephron epithelium

[Term]
id: UBERON:0005153
name: epithelial bud
namespace: uberon
def: "A bud is a protrusion that forms from an epithelial sheet by localized folding." [GO:0060572]
xref: BTO:0001639
is_a: UBERON:0005157 ! epithelial fold

[Term]
id: UBERON:0005154
name: epithelial cord
namespace: uberon
def: "A cord of epithelial cells without a lumen and usually several cells thick." [AEO:0000216]
xref: AEO:0000216
xref: EHDAA2:0004052
is_a: UBERON:0000486 {source="AEO"} ! multilaminar epithelium

[Term]
id: UBERON:0005156
name: reproductive structure
namespace: uberon
def: "Any anatomical structure that is part of the reproductive system." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "reproductive system element" EXACT []
synonym: "reproductive system structure" EXACT []
is_a: UBERON:0010000 ! multicellular anatomical structure
intersection_of: UBERON:0010000 ! multicellular anatomical structure
intersection_of: part_of UBERON:0000990 ! reproductive system
relationship: part_of UBERON:0000990 ! reproductive system

[Term]
id: UBERON:0005157
name: epithelial fold
namespace: uberon
def: "An epithelial sheet bent on a linear axis." [GO:0060571]
is_a: UBERON:0000483 ! epithelium

[Term]
id: UBERON:0005158
name: parenchyma of central nervous system
namespace: uberon
def: "The functional tissue of the central nervous system consisting of neurons and glial cells." [CL:tm, https://github.com/obophenotype/uberon/issues/8]
synonym: "central nervous system parenchyma" EXACT [OBOL:automatic]
synonym: "CNS parenchyma" EXACT [OBOL:automatic]
synonym: "parenchyma of central nervous system" EXACT []
synonym: "parenchyma of CNS" EXACT [OBOL:automatic]
is_a: UBERON:0000353 ! parenchyma
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000353 ! parenchyma
intersection_of: part_of UBERON:0001017 ! central nervous system
relationship: part_of UBERON:0001017 ! central nervous system
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/tmeehan

[Term]
id: UBERON:0005162
name: multi cell part structure
namespace: uberon
def: "A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part." [CARO:0001000]
subset: upper_level
synonym: "cell part cluster" RELATED [FMA:83115]
synonym: "multi-cell-component structure" EXACT [CARO:0001000]
synonym: "multi-cell-part structure" EXACT [CARO:0001000]
xref: AAO:0011000
xref: CARO:0001000
xref: FBbt:00007060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:83115
is_a: UBERON:0000061 ! anatomical structure
relationship: composed_primarily_of GO:0005575 ! cellular_component
property_value: UBPROP:0000012 "we go with the FMA classification rather than the CARO one. FMA def: 'Anatomical cluster which has as direct parts cell parts from two or more cells.'" xsd:string {external_ontology="CARO", external_ontology="FMA"}

[Term]
id: UBERON:0005169
name: interstitial tissue
namespace: uberon
def: "Connective tissue between the cellular elements of a structure." [http://medical-dictionary.thefreedictionary.com/tissue]
subset: human_reference_atlas
subset: pheno_slim
synonym: "interstitium" EXACT []
xref: FMA:86301
xref: SCTID:85293002
is_a: UBERON:0003891 {source="FMA"} ! stroma
property_value: editor_note "specify differentia from stroma" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000007 "interstital" xsd:string

[Term]
id: UBERON:0005171
name: hepatic duct
namespace: uberon
def: "Any portion of the ducts that carry bile from the liver to the common bile duct. This may include both intrahapetic components (parts of left and right hepatic ducts) and extrahapetic components (common hepatic duct, plus hilar portion)." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: vertebrate_core
xref: EHDAA2:0000741
xref: EHDAA:3049
xref: EMAPA:16843
xref: FMA:71891
xref: galen:HepaticDuct
xref: MA:0000357
xref: NCIT:C32730
xref: SCTID:245399002
xref: UMLS:C0917710 {source="ncithesaurus:Hepatic_Duct"}
xref: VHOG:0000219
is_a: UBERON:0002394 ! bile duct
relationship: connects UBERON:0001174 ! common bile duct
relationship: connects UBERON:0002107 ! liver
property_value: editor_note "TODO - MA distinguishes between bile duct, hepatic duct, common bile duct and common hepatic duct. in FMA hepatic duct and common hepatic duct are the same" xsd:string
property_value: UBPROP:0000001 "A duct that carries bile from the liver to the small intestine.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001100", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The excretory duct of the liver or one of its branches in the lobes of the liver. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000219", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/hepatic+duct"}
property_value: UBPROP:0000001 "The hepatic duct is the duct that leads from the liver to the bile duct[GO]." xsd:string {source="GO:0061011"}

[Term]
id: UBERON:0005172
name: abdomen element
namespace: uberon
def: "An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
synonym: "abdomen organ" EXACT [MA:0000522]
xref: MA:0000522
xref: SCTID:272631008
is_a: UBERON:0005173 ! abdominal segment element
intersection_of: UBERON:0000062 ! organ
intersection_of: part_of UBERON:0000916 ! abdomen
relationship: part_of UBERON:0000916 ! abdomen

[Term]
id: UBERON:0005173
name: abdominal segment element
namespace: uberon
def: "An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
synonym: "abdominal segment organ" EXACT [MA:0000529]
xref: EMAPA:37062 {source="MA:th"}
xref: MA:0000529
is_a: UBERON:0005177 ! trunk region element
intersection_of: UBERON:0000062 ! organ
intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk
relationship: part_of UBERON:0002417 ! abdominal segment of trunk

[Term]
id: UBERON:0005174
name: dorsal region element
namespace: uberon
def: "An organ or element that part of the dorsum of the organism. Examples: spinal cord, vertebrae, muscles of back." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
synonym: "back organ" EXACT [MA:0001901]
synonym: "dorsal region organ" EXACT []
xref: EMAPA:37274 {source="MA:th"}
xref: MA:0001901
is_a: UBERON:0000062 ! organ
intersection_of: UBERON:0000062 ! organ
intersection_of: part_of UBERON:0001137 ! dorsum
relationship: part_of UBERON:0001137 ! dorsum

[Term]
id: UBERON:0005177
name: trunk region element
namespace: uberon
def: "An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
subset: organ_slim
synonym: "trunk organ" EXACT [MA:0000516]
xref: EMAPA:37270 {source="MA:th"}
xref: MA:0000516
is_a: UBERON:0000062 ! organ
intersection_of: UBERON:0000062 ! organ
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk

[Term]
id: UBERON:0005178
name: thoracic cavity element
namespace: uberon
def: "An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
subset: pheno_slim
synonym: "thoracic cavity organ" EXACT [MA:0000557]
xref: EMAPA:37273 {source="MA:th"}
xref: MA:0000557
is_a: UBERON:0002075 ! viscus
is_a: UBERON:0005181 ! thoracic segment organ
intersection_of: UBERON:0000062 ! organ
intersection_of: located_in UBERON:0002224 ! thoracic cavity
relationship: located_in UBERON:0002224 ! thoracic cavity

[Term]
id: UBERON:0005179
name: pelvic region element
namespace: uberon
def: "An organ or element that is part of the pelvic region. Examples: reproductive organs (in some organisms), urinary bladder, bones of the pelvis." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
subset: organ_slim
subset: pheno_slim
synonym: "pelvic element" EXACT []
synonym: "pelvis organ" EXACT [MA:0000543]
synonym: "pelvis region organ" EXACT []
xref: EMAPA:37275 {source="MA:th"}
xref: MA:0000543
is_a: UBERON:0005173 ! abdominal segment element
intersection_of: UBERON:0000062 ! organ
intersection_of: part_of UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0002355 ! pelvic region of trunk

[Term]
id: UBERON:0005181
name: thoracic segment organ
namespace: uberon
def: "An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
synonym: "upper body organ" RELATED [MA:0000563]
xref: EMAPA:37271 {source="MA:th"}
xref: MA:0000563
is_a: UBERON:0005177 ! trunk region element
intersection_of: UBERON:0000062 ! organ
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0000915 ! thoracic segment of trunk

[Term]
id: UBERON:0005192
name: deferent duct artery
namespace: uberon
def: "An artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]." [Wikipedia:Artery_to_the_ductus_deferens]
subset: human_reference_atlas
synonym: "arteria ductus deferentis" EXACT OMO:0003011 [Wikipedia:Artery_to_the_ductus_deferens]
synonym: "artery of ductus deferens" EXACT [FMA:18930]
synonym: "ductus deferens artery" EXACT [FMA:18930]
synonym: "vas deferens artery" EXACT []
xref: EMAPA:37513 {source="MA:th"}
xref: FMA:18930
xref: MA:0001940
xref: SCTID:279659005
xref: Wikipedia:Artery_to_the_ductus_deferens
is_a: UBERON:0001637 ! artery
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001000 ! vas deferens
relationship: connecting_branch_of UBERON:0001312 {source="Wikipedia"} ! superior vesical artery
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0005352 ! spermatic cord
relationship: supplies UBERON:0001000 ! vas deferens
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0005194
name: thoracic vein
namespace: uberon
def: "A vein that is part of a thorax [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:37197 {source="MA:th"}
xref: MA:0002235
xref: NCIT:C53142
xref: SCTID:281472008
xref: UMLS:C0226629 {source="ncithesaurus:Thoracic_Vein"}
is_a: UBERON:0001638 ! vein
is_a: UBERON:0003834 ! thoracic segment blood vessel
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk

[Term]
id: UBERON:0005195
name: deferent duct vein
namespace: uberon
def: "A vein that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:37514 {source="MA:th"}
xref: MA:0002100
is_a: UBERON:0001638 ! vein
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0001000 ! vas deferens
relationship: part_of UBERON:0001000 ! vas deferens

[Term]
id: UBERON:0005208
name: right atrium valve
namespace: uberon
def: "A valve that is part of a right atrium [Automatically generated definition]." [OBOL:automatic]
synonym: "right atrium valves" RELATED OMO:0003004 [EHDAA2:0000302]
synonym: "superior vena cava valve" RELATED [EMAPA:17327]
synonym: "valve of right atrium" EXACT [EMAPA:17327]
xref: EHDAA2:0000302
xref: EMAPA:17327
xref: MA:0001871
is_a: UBERON:0003978 ! valve
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0003978 ! valve
intersection_of: part_of UBERON:0002078 ! right cardiac atrium
relationship: part_of UBERON:0002078 ! right cardiac atrium

[Term]
id: UBERON:0005215
name: kidney interstitium
namespace: uberon
def: "The interstitial compartment of the kidney, comprising the extravascular intertubular spaces of the renal parenchyma, with their attendant cellular elements and extracellular substances, bounded on all sides by epithelial and vascular basement membranes." [DOI:10.1038/ki.1991.49, http://orcid.org/0000-0002-6601-2165, PMID:18575881]
subset: human_reference_atlas
subset: pheno_slim
synonym: "interstitial tissue of kidney" EXACT []
synonym: "kidney interstitium group" RELATED [EMAPA:28518]
synonym: "renal interstitial tissue" EXACT []
synonym: "renal interstitium" EXACT [FMA:70983]
synonym: "renal stroma" EXACT [FMA:70983]
synonym: "stroma of kidney" EXACT [FMA:70983]
xref: EMAPA:28518
xref: FMA:70983
xref: MA:0002616
xref: NCIT:C33459
xref: SCTID:362210003
is_a: UBERON:0005169 ! interstitial tissue
intersection_of: UBERON:0005169 ! interstitial tissue
intersection_of: part_of UBERON:0002113 ! kidney
relationship: composed_primarily_of CL:1000692 ! kidney interstitial fibroblast
relationship: contributes_to_morphology_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0002113 ! kidney
property_value: editor_note "See https://sourceforge.net/p/geneontology/ontology-requests/10941/" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000009 "The interstitium is necessarily involved in all intrarenal exchange processes since the reabsorption and secretion of fluid and solutes implicates a transit across the interstitial compartment." xsd:string
property_value: UBPROP:0000010 "The fibroblasts in the interstitium provide the 'skeleton' of the tissue and maintain the three-dimensional architecture of the tissue." xsd:string

[Term]
id: UBERON:0005221
name: liver right lobe parenchyma
namespace: uberon
def: "A parenchyma that is part of a right lobe of liver [Automatically generated definition]." [OBOL:automatic]
synonym: "parenchyma of right lobe of liver" EXACT [FMA:71657]
xref: EHDAA2:0001010
xref: EMAPA:18317
xref: FMA:71657
xref: VHOG:0000840
is_a: UBERON:0001280 ! liver parenchyma
intersection_of: UBERON:0000353 ! parenchyma
intersection_of: part_of UBERON:0001114 ! right lobe of liver
relationship: part_of UBERON:0001114 ! right lobe of liver

[Term]
id: UBERON:0005222
name: liver left lobe parenchyma
namespace: uberon
def: "A parenchyma that is part of a left lobe of liver [Automatically generated definition]." [OBOL:automatic]
synonym: "parenchyma of left lobe of liver" EXACT [FMA:71658]
xref: EHDAA2:0001002
xref: EMAPA:18310
xref: FMA:71658
xref: VHOG:0000839
is_a: UBERON:0001280 ! liver parenchyma
intersection_of: UBERON:0000353 ! parenchyma
intersection_of: part_of UBERON:0001115 ! left lobe of liver
relationship: part_of UBERON:0001115 ! left lobe of liver

[Term]
id: UBERON:0005233
name: medial-nasal process ectoderm
namespace: uberon
def: "An ectoderm that is part of a medial nasal prominence [Automatically generated definition]." [OBOL:automatic]
xref: EHDAA2:0001078
xref: EMAPA:16809
xref: FMA:312675
xref: VHOG:0000803
is_a: UBERON:0000924 ! ectoderm
is_a: UBERON:0014702 ! frontonasal process epithelium
intersection_of: UBERON:0000924 ! ectoderm
intersection_of: part_of UBERON:0004068 ! medial nasal prominence
relationship: part_of UBERON:0004068 ! medial nasal prominence

[Term]
id: UBERON:0005234
name: optic eminence ectoderm
namespace: uberon
def: "An ectoderm that is part of a optic eminence [Automatically generated definition]." [OBOL:automatic]
xref: EHDAA:940
xref: EMAPA:16539
xref: RETIRED_EHDAA2:0001309
xref: VHOG:0001105
is_a: UBERON:0000924 ! ectoderm
intersection_of: UBERON:0000924 ! ectoderm
intersection_of: part_of UBERON:0004348 ! optic eminence
relationship: part_of UBERON:0004348 ! optic eminence

[Term]
id: UBERON:0005239
name: basal plate metencephalon
namespace: uberon
synonym: "metencephalon basal plate" EXACT [EHDAA2:0001154]
xref: EHDAA2:0001154
xref: EMAPA:17078
xref: VHOG:0000320
is_a: UBERON:0004064 ! neural tube basal plate
property_value: UBPROP:0000001 "The ventral half of the developing neural tube that is the metencephalon. [Chordate_evolution_and_the_origin_of_craniates:_An_old_brain_in_a_new_head._AnaT_Rec_(New_Anat)_(2000)_261(3):_111-125, See_Butler_AB][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000320", ontology="VHOG", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005243
name: interventricular septum endocardium
namespace: uberon
def: "An endocardium that is part of a interventricular septum [Automatically generated definition]." [OBOL:automatic]
synonym: "endocardium of interventricular septum" EXACT [FMA:83584]
synonym: "interventricular septum endocardial tissue" RELATED [VHOG:0000615]
xref: EHDAA2:0000886
xref: EHDAA2:0000887
xref: FMA:83584
xref: VHOG:0000615
is_a: UBERON:0002165 ! endocardium
intersection_of: UBERON:0002165 ! endocardium
intersection_of: part_of UBERON:0002094 ! interventricular septum
relationship: part_of UBERON:0002094 ! interventricular septum
property_value: editor_note "TODO - split?" xsd:string

[Term]
id: UBERON:0005248
name: bulbus cordis myocardium
namespace: uberon
def: "A myocardium that is part of a bulbus cordis [Automatically generated definition]." [OBOL:automatic]
synonym: "bulbus cordis cardiac muscle" RELATED [VHOG:0000609]
xref: EMAPA:36488
xref: VHOG:0000609
is_a: UBERON:0002349 ! myocardium
intersection_of: UBERON:0002349 ! myocardium
intersection_of: part_of UBERON:0004706 ! bulbus cordis
relationship: part_of UBERON:0004706 ! bulbus cordis

[Term]
id: UBERON:0005249
name: metanephric renal pelvis
namespace: uberon
def: "A renal pelvis that is part of a metanephros." [OBOL:automatic]
synonym: "metanephros pelvis" EXACT [VHOG:0000945]
xref: VHOG:0000945
is_a: UBERON:0001224 ! renal pelvis
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0001224 ! renal pelvis
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: part_of UBERON:0000081 ! metanephros
property_value: UBPROP:0000003 "The ureteric bud itself forms the collecting tubules and the ureter that drain the adult kidney. This type of kidney, called the metanephros, occurs in all adult amniotes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000945", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005250
name: stomatodeum gland
namespace: uberon
def: "A gland that is part of a stomodeum." [OBOL:automatic]
subset: organ_slim
synonym: "stomatodaeum gland" EXACT [VHOG:0000658]
xref: VHOG:0000658
is_a: UBERON:0002530 ! gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0000930 ! stomodeum
relationship: part_of UBERON:0000930 ! stomodeum
property_value: editor_note "check this" xsd:string

[Term]
id: UBERON:0005251
name: yolk sac cavity
namespace: uberon
def: "An anatomical cavity that is part of a yolk sac [Automatically generated definition]." [OBOL:automatic]
synonym: "cavity of yolk sac" EXACT [FMA:63942]
synonym: "yolk sac lumen" EXACT []
synonym: "yolk sac space" RELATED [FMA:63942]
xref: EMAPA:16055
xref: FMA:63942
xref: VHOG:0000843
is_a: UBERON:0002553 ! anatomical cavity
is_a: UBERON:0007473 ! lumen of epithelial sac
is_a: UBERON:0012466 ! extraembryonic cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0001040 ! yolk sac
relationship: luminal_space_of UBERON:0001040 ! yolk sac
relationship: part_of UBERON:0001040 ! yolk sac
property_value: UBPROP:0000008 "In mammals, the yolk sac cavity contains fluid rather than platelets" xsd:string {source="ISBN:0073040584"}
property_value: UBPROP:0000012 "in EHDAA2, there are separate primary and secondary yolk sac cavities" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0005253
name: head mesenchyme
namespace: uberon
def: "Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells." [ISBN:0683400088, MP:0011260]
subset: efo_slim
subset: pheno_slim
subset: vertebrate_core
synonym: "cephalic mesenchyme" EXACT [MP:0011260]
synonym: "cranial mesenchyme" RELATED [MGI:anna]
synonym: "desmocranium" RELATED PENDING_REVIEW [FMA:76622]
xref: EFO:0003492
xref: EHDAA2:0000732
xref: EHDAA:179
xref: EMAPA:16098
xref: EMAPA_RETIRED:16269
xref: FMA:76622
xref: TAO:0000113
xref: VHOG:0000332
xref: ZFA:0000113
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0005291 ! embryonic tissue
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0009142 {source="EHDAA2"} ! entire embryonic mesenchyme
property_value: UBPROP:0000001 "Mesoderm that will give rise, along with cranial neural crest cells, to connective tissue, bone and musculature in the head. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000113", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0005256
name: trunk mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a developing trunk." [OBOL:automatic]
subset: efo_slim
subset: vertebrate_core
synonym: "trunk and cervical mesenchyme" RELATED [EHDAA2:0002092]
xref: EFO:0003485
xref: EHDAA2:0002092
xref: EHDAA:377
xref: EMAPA:16177
xref: TAO:0000081
xref: VHOG:0000281
xref: ZFA:0000081
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0005291 ! embryonic tissue
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0000922 ! embryo
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0009142 {source="EHDAA2"} ! entire embryonic mesenchyme

[Term]
id: UBERON:0005268
name: renal cortex artery
namespace: uberon
def: "An artery that supplies the renal cortex." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "kidney cortex artery" EXACT [MP:0011314]
synonym: "renal cortex arterial system" RELATED [MA:0002582]
synonym: "renal cortex artery" EXACT [MA:0002582]
xref: EMAPA:28147
xref: MA:0002582
is_a: UBERON:0001637 ! artery
is_a: UBERON:0003644 ! kidney arterial blood vessel
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001225 ! cortex of kidney
relationship: contributes_to_morphology_of UBERON:0001225 ! cortex of kidney
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney
relationship: supplies UBERON:0001225 ! cortex of kidney

[Term]
id: UBERON:0005269
name: renal cortex vein
namespace: uberon
def: "Artery that receives blood from the renal cortex[MP, modified]." [MGI:csmith]
subset: pheno_slim
synonym: "kidney cortex vein" RELATED [MP:0011322]
synonym: "renal cortex venous system" RELATED [MA:0002592]
xref: EMAPA:28152
xref: MA:0002592
is_a: UBERON:0013126 ! vein of abdomen
is_a: UBERON:0014401 ! renal venous blood vessel
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0001225 ! cortex of kidney
relationship: contributes_to_morphology_of UBERON:0001225 ! cortex of kidney
relationship: drains UBERON:0001225 ! cortex of kidney
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney

[Term]
id: UBERON:0005270
name: renal cortex interstitium
namespace: uberon
def: "A compartment of the renal cortex situated between basement membranes of epithelia and vessels that contains two contiguous cellular networks in mutual contact, one formed by interstitial fibroblasts, the other by dendritic cells." [PMID:18575881]
synonym: "cortical stroma" RELATED [EMAPA:28136]
synonym: "kidney cortex interstitium" EXACT [MA:0002608]
synonym: "renal cortical interstitial tissue" EXACT []
xref: EMAPA:28136
xref: MA:0002608
xref: SCTID:243707006
xref: Wikipedia:Medullary_interstitium
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0005215 ! kidney interstitium
intersection_of: UBERON:0005169 ! interstitial tissue
intersection_of: part_of UBERON:0001225 ! cortex of kidney
relationship: has_part CL:0000057 ! fibroblast
relationship: has_part CL:0000451 ! dendritic cell
relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney
relationship: part_of UBERON:0005215 {source="MA"} ! kidney interstitium
property_value: UBPROP:0000010 "In the renal cortex, interstitial fibroblasts produce erythropoietin and are distinguished from other interstitial cells by their prominent F-actin cytoskeleton, abundance of rough endoplasmic reticulum, and by ecto-5'-nucleotidase expression in their plasma membrane. The resident dendritic cells belong to the mononuclear phagocyte system and fulfil a sentinel function. They are characterized by their expression of MHC class II and CD11c." xsd:string {source="PMID:18575881"}

[Term]
id: UBERON:0005290
name: myelencephalon
namespace: uberon
def: "The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]." [BTO:0000758, Wikipedia:Myelencephalon]
subset: uberon_slim
synonym: "myelencephalon (medulla oblongata)" RELATED [DHBA:10662]
xref: BTO:0000758
xref: CALOHA:TS-0607
xref: CALOHA:TS-2365
xref: DHBA:10662
xref: EHDAA2:0001207
xref: EHDAA:5526
xref: EMAPA:17082
xref: HBA:9512
xref: MA:0000205
xref: MESH:D054024 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: VHOG:0000456
xref: Wikipedia:Myelencephalon
is_a: UBERON:0004733 ! segmental subdivision of hindbrain
relationship: develops_from UBERON:0010096 ! future myelencephalon
relationship: immediate_transformation_of UBERON:0010096 {evidence="definitional"} ! future myelencephalon
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg" xsd:anyURI
property_value: RO:0002174 NCBITaxon:7955
property_value: UBPROP:0000001 "The posterior of the two brain vesicles formed by specialization of the rhombencephalon in the developing embryo, it comprises the medulla oblongata. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000456", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/myelencephalon"}
property_value: UBPROP:0000003 "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000456", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) p.381-382, ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000013 "the terms metencephalon and myelencephalon are only meaningful in mammals and birds - Neuroanatomy of the Zebrafish Brain. Note that its not clear if this refers to the developing medulla oblongata - MA (adult) has two distinct classes" xsd:string

[Term]
id: UBERON:0005291
name: embryonic tissue
namespace: uberon
def: "A portion of tissue that is part of an embryo." [OBOL:automatic]
subset: pheno_slim
subset: upper_level
synonym: "developing tissue" RELATED []
synonym: "portion of embryonic tissue" EXACT [OBOL:automatic]
xref: CALOHA:TS-2100
is_a: UBERON:0000479 ! tissue
intersection_of: UBERON:0000479 ! tissue
intersection_of: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0002050 ! embryonic structure

[Term]
id: UBERON:0005292
name: extraembryonic tissue
namespace: uberon
def: "Portion of tissue that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo." [https://orcid.org/0000-0002-6601-2165]
subset: efo_slim
synonym: "extra-embryonic tissue" EXACT []
xref: BTO:0003360
xref: CALOHA:TS-2119
xref: EFO:0001406
xref: MAT:0000061
xref: MIAA:0000061
is_a: UBERON:0000479 ! tissue
intersection_of: UBERON:0000479 ! tissue
intersection_of: part_of UBERON:0016887 ! entire extraembryonic component
relationship: part_of UBERON:0016887 ! entire extraembryonic component

[Term]
id: UBERON:0005294
name: gonadal ridge
namespace: uberon
def: "The elevation of thickened mesothelium and underlying mesenchyme found on the ventromedial border of the embryonic mesonephros in which the primordial germ cells become embedded, establishing it as the primordium of the testis or ovary." [MGI:anna, MP:0011411]
subset: efo_slim
subset: pheno_slim
synonym: "crista gonadalis" RELATED OMO:0003011 [Wikipedia:Gonadal_ridge]
synonym: "genital cord" RELATED [MP:0011411]
synonym: "genital ridge" EXACT [MP:0011411, Wikipedia:Gonadal_ridge]
synonym: "gonadal ridge" EXACT [Wikipedia:Gonadal_ridge]
synonym: "indifferent gonadal ridge" EXACT [http://orcid.org/0000-0002-6601-2165]
xref: AAO:0011047
xref: BTO:0001402
xref: EFO:0001414
xref: EHDAA2:0004044
xref: EMAPA:35899
xref: FMA:321917
xref: NCIT:C34184
xref: NCIT:C34321
xref: SCTID:308801004
xref: SCTID:361399001
xref: UMLS:C0231047 {source="ncithesaurus:Urogenital_Ridge"}
xref: UMLS:C1512243 {source="ncithesaurus:Gonadal_Ridge"}
xref: Wikipedia:Gonadal_ridge
xref: XAO:0000018
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0004876 ! urogenital fold
relationship: part_of UBERON:0004122 ! genitourinary system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1106.png" xsd:anyURI
property_value: editor_note "TODO - check developmental relationships. merge with urogenital ridge?" xsd:string
property_value: UBPROP:0000011 "in eutherians, SRY transforms the indifferent gonad into testes" xsd:string

[Term]
id: UBERON:0005295
name: sex cord
namespace: uberon
def: "Cordlike masses of epithelial tissue that invaginate from germinal epithelium of the gonad and give rise to seminiferous tubules and rete testes in the male, and primary ovarian follicles and rete ovarii in the female." [http://www.answers.com/topic/sex-cord, Wikipedia:Sex_cords]
synonym: "genital cord" RELATED []
synonym: "gonad cord" RELATED []
synonym: "gonadal cord" RELATED []
synonym: "primitive sex cord" RELATED []
xref: EHDAA2:0004051
xref: NCIT:C34183
xref: RETIRED_EHDAA2:0001523
xref: SCTID:343823004
xref: UMLS:C1512242 {source="ncithesaurus:Gonadal_Cord"}
xref: Wikipedia:Sex_cords
is_a: UBERON:0005154 {source="EHDAA2"} ! epithelial cord
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0012275 ! meso-epithelium
relationship: develops_from UBERON:0005294 ! gonadal ridge

[Term]
id: UBERON:0005296
name: ovary sex cord
namespace: uberon
def: "Structures that develop from sex cords in the female. After further development they become the ovarian follicles." [Wikipedia:Cortical_cords]
synonym: "cortical cord" RELATED []
synonym: "cortical sex cord" RELATED []
synonym: "ovary primitive sex cord" RELATED []
synonym: "ovigerous cord" EXACT []
synonym: "ovigerous cords" EXACT OMO:0003004 [VHOG:0001339]
synonym: "secondary cord" RELATED []
xref: EHDAA2:0001363
xref: EHDAA:8130
xref: EMAPA:31058
xref: NCIT:C34134
xref: UMLS:C1511527 {source="ncithesaurus:Cortical_Cord"}
xref: VHOG:0001339
xref: Wikipedia:Cortical_cords
is_a: UBERON:0004911 ! epithelium of female gonad
is_a: UBERON:0005295 ! sex cord
intersection_of: UBERON:0005295 ! sex cord
intersection_of: part_of UBERON:0000992 ! ovary
relationship: develops_from UBERON:0010141 ! primitive sex cord of indifferent gonad
property_value: editor_note "TODO check secondary vs cortical vs ovary" xsd:string

[Term]
id: UBERON:0005297
name: testis sex cord
namespace: uberon
def: "The testis cords are precursors to the rete testis. They play several different roles in the development of the male genitals[WP]." [Wikipedia:Testis_cords]
subset: pheno_slim
synonym: "primary sex cord" RELATED []
synonym: "testis cord" EXACT [MP:0006424]
synonym: "testis primary sex cords" EXACT [EHDAA2:0002011]
synonym: "testis primitive sex cord" RELATED []
xref: EHDAA2:0002011
xref: EHDAA:8152
xref: EMAPA:29098
xref: VHOG:0001321
xref: Wikipedia:Testis_cords
is_a: UBERON:0004910 ! epithelium of male gonad
is_a: UBERON:0005295 ! sex cord
intersection_of: UBERON:0005295 ! sex cord
intersection_of: part_of UBERON:0000473 ! testis
relationship: develops_from UBERON:0010141 ! primitive sex cord of indifferent gonad
relationship: immediate_transformation_of UBERON:0010141 {source="Bgee:AN"} ! primitive sex cord of indifferent gonad
property_value: editor_note "TODO - check primary vs testis" xsd:string

[Term]
id: UBERON:0005298
name: skin of clitoris
namespace: uberon
def: "A zone of skin that is part of a clitoris [Automatically generated definition]." [OBOL:automatic]
synonym: "clitoris skin" EXACT []
xref: FMA:20168
xref: SCTID:361374002
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:8480029 ! skin of external genitalia
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0002411 ! clitoris
relationship: part_of UBERON:0002411 ! clitoris

[Term]
id: UBERON:0005309
name: pronephric nephron
namespace: uberon
def: "A pronephric nephron is the functional unit of the pronephros[GO]." [GO:0039019]
xref: AAO:0011091
xref: XAO:0000285
is_a: UBERON:0001285 ! nephron
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0001285 ! nephron
intersection_of: part_of UBERON:0002120 ! pronephros
relationship: part_of UBERON:0002120 ! pronephros
property_value: UBPROP:0000001 "The structure that is the basic functional unit of the pronephros.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011091", ontology="AAO", source="UBERON:0005309"}

[Term]
id: UBERON:0005310
name: pronephric nephron tubule
namespace: uberon
def: "The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct[GO]." [GO:0039020]
synonym: "ciliated neck segment" RELATED [ZFA:0001558]
synonym: "pronephric tubule" EXACT [ZFA:0001558]
xref: TAO:0001558
xref: XAO:0004105
xref: ZFA:0001558
is_a: UBERON:0001231 ! nephron tubule
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0001231 ! nephron tubule
intersection_of: part_of UBERON:0005309 ! pronephric nephron
relationship: part_of UBERON:0005309 {source="GO"} ! pronephric nephron
property_value: RO:0002174 NCBITaxon:32524 {source="ISBN:0073040584"}
property_value: UBPROP:0000001 "Bilaterally paired tubes connecting the pronephric glomeruli to the pronephric ducts. In zebrafish and other teleosts, the pronephric nephron and tubules form after the pronephric duct, connecting to the anterior-most tip of the pronephric ducts. Drummond, 2000.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001558", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0005316
name: endocardial endothelium
namespace: uberon
def: "The endothelial lining of the endocardium." [UBERON:cjm]
synonym: "endocardium endothelium" EXACT [FMA:83596]
synonym: "endothelium of endocardium" EXACT [FMA:83596]
xref: FMA:83596
is_a: UBERON:0008307 ! heart endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0002165 ! endocardium
relationship: part_of UBERON:0002165 ! endocardium

[Term]
id: UBERON:0005317
name: pulmonary artery endothelium
namespace: uberon
def: "An pulmonary artery endothelium is an epithelium that lines the pulmonary artery[GO]." [GO:0061155]
synonym: "pulmonary artery endothelial tube" EXACT [GO:0061155]
xref: BTO:0000137
is_a: UBERON:0001917 ! endothelium of artery
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0002012 ! pulmonary artery
relationship: part_of UBERON:0002012 ! pulmonary artery

[Term]
id: UBERON:0005319
name: mesonephric collecting duct
namespace: uberon
def: "The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder[GO]." [GO:0061211]
xref: AAO:0010390
xref: XAO:0000151
is_a: UBERON:0001232 ! collecting duct of renal tubule
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0001232 ! collecting duct of renal tubule
intersection_of: part_of UBERON:0000080 ! mesonephros
relationship: part_of UBERON:0005322 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric nephron

[Term]
id: UBERON:0005321
name: mesonephric smooth muscle tissue
namespace: uberon
def: "Missing definition for term UBERON:0005321. Please replace it using linked reference." [GO:0061214]
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0000080 ! mesonephros
relationship: part_of UBERON:0000080 ! mesonephros

[Term]
id: UBERON:0005322
name: mesonephric nephron
namespace: uberon
def: "A nephron that is part of a mesonephros." [http://orcid.org/0000-0002-6601-2165]
synonym: "nephron of mesonephros" EXACT []
synonym: "stage IV nephron" RELATED [ZFA:0005592]
xref: AAO:0010387
xref: XAO:0000292
xref: ZFA:0005592
is_a: UBERON:0001285 ! nephron
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0001285 ! nephron
intersection_of: part_of UBERON:0000080 ! mesonephros
relationship: develops_from UBERON:0005323 {source="XAO"} ! mesonephric mesenchyme
relationship: part_of UBERON:0000080 ! mesonephros
property_value: UBPROP:0000001 "The structure that is the basic functional unit of the kidney.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010387", ontology="AAO", source="PMID:9268568"}

[Term]
id: UBERON:0005323
name: mesonephric mesenchyme
namespace: uberon
def: "Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros[GO]." [GO:0061219]
subset: pheno_slim
xref: AAO:0011062
xref: EHDAA2:0001132
xref: EMAPA:16745
xref: XAO:0000291
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0000080 ! mesonephros
relationship: part_of UBERON:0000080 ! mesonephros

[Term]
id: UBERON:0005330
name: mesonephric nephron epithelium
namespace: uberon
def: "The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros[GO]." [GO:0061241]
is_a: UBERON:0004211 ! nephron epithelium
is_a: UBERON:0005103 ! mesonephric epithelium
intersection_of: UBERON:0004211 ! nephron epithelium
intersection_of: part_of UBERON:0000080 ! mesonephros
relationship: part_of UBERON:0005322 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric nephron

[Term]
id: UBERON:0005331
name: mesonephric renal vesicle
namespace: uberon
def: "The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]." [GO:0061243]
synonym: "mesonephric vesicle" EXACT []
xref: SCTID:361407006
xref: ZFA:0005586
is_a: UBERON:0004209 ! renal vesicle
is_a: UBERON:0005103 ! mesonephric epithelium
intersection_of: UBERON:0004209 ! renal vesicle
intersection_of: part_of UBERON:0000080 ! mesonephros
relationship: develops_from UBERON:0010534 {source="ZFA"} ! primitive mesonephric nephron
relationship: has_potential_to_develop_into UBERON:0005330 ! mesonephric nephron epithelium

[Term]
id: UBERON:0005334
name: oral lamina propria
namespace: uberon
def: "A lamina propria that is part of a mucosa of oral region." [OBOL:automatic]
synonym: "lamina propria of oral mucosa" EXACT []
xref: EMAPA:26947
is_a: UBERON:0000030 ! lamina propria
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0003343 ! mucosa of oral region
relationship: part_of UBERON:0003343 ! mucosa of oral region

[Term]
id: UBERON:0005337
name: outflow tract of ventricle
namespace: uberon
def: "A ventricular outflow tract is a portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]." [Wikipedia:Ventricular_outflow_tract]
synonym: "heart ventricle outflow tract" EXACT [MP:0010224]
synonym: "outflow part of ventricle" EXACT []
synonym: "ventricular outflow tract" EXACT [Wikipedia:Ventricular_outflow_tract]
xref: FMA:13225
xref: Wikipedia:Ventricular_outflow_tract
xref: XAO:0004140
is_a: UBERON:0004145 ! outflow tract
intersection_of: UBERON:0004145 ! outflow tract
intersection_of: part_of UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0002082 ! cardiac ventricle

[Term]
id: UBERON:0005338
name: outflow tract aortic component
namespace: uberon
def: "An outflow tract that is part of a aorta." [OBOL:automatic]
xref: EHDAA2:0001353
xref: EMAPA:17329
xref: MA:0000101
xref: VHOG:0001394
is_a: UBERON:0004145 ! outflow tract
intersection_of: UBERON:0004145 ! outflow tract
intersection_of: part_of UBERON:0000947 ! aorta
relationship: part_of UBERON:0000947 ! aorta
property_value: editor_note "merge with LVOT?" xsd:string

[Term]
id: UBERON:0005339
name: outflow tract pulmonary component
namespace: uberon
xref: EHDAA2:0001359
xref: EHDAA:4401
xref: EMAPA:17330
xref: MA:0000102
xref: VHOG:0001395
is_a: UBERON:0004145 ! outflow tract
property_value: editor_note "merge with RVOT?" xsd:string

[Term]
id: UBERON:0005352
name: spermatic cord
namespace: uberon
def: "The cord-like structure in males comprising the vas deferens and associated tissue that runs from the abdomen down to each testis[MP]." [MP:0010145, Wikipedia:Spermatic_cord]
subset: pheno_slim
synonym: "funiculus spermaticus" RELATED OMO:0003011 [Wikipedia:Spermatic_cord]
synonym: "spermatic chord" RELATED []
xref: FMA:19937
xref: GAID:395
xref: MESH:D013085
xref: NCIT:C12329
xref: SCTID:181433005
xref: UMLS:C0037855 {source="ncithesaurus:Spermatic_Cord"}
xref: Wikipedia:Spermatic_cord
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0034921 ! multi organ part structure
relationship: contributes_to_morphology_of UBERON:0004054 ! internal male genitalia
relationship: has_part UBERON:0001000 ! vas deferens
relationship: part_of UBERON:0004054 ! internal male genitalia
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png" xsd:anyURI

[Term]
id: UBERON:0005388
name: photoreceptor array
namespace: uberon
def: "An array of photoreceptors and any supporting cells found in an eye." [https://orcid.org/0000-0002-6601-2165]
synonym: "light-sensitive tissue" EXACT []
xref: FBbt:00004200 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: composed_primarily_of CL:0000210 ! photoreceptor cell
intersection_of: part_of UBERON:0000970 ! eye
relationship: composed_primarily_of CL:0000210 ! photoreceptor cell
relationship: part_of UBERON:0000970 ! eye
relationship: part_of UBERON:0001016 ! nervous system

[Term]
id: UBERON:0005389
name: transparent eye structure
namespace: uberon
def: "A transparent structure that is part of a visual sense organ, the function of which is to direct or focus light onto a photoreceptor array." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "lens" NARROW []
is_a: UBERON:0000061 ! anatomical structure
relationship: has_quality PATO:0000964 ! transparent
relationship: part_of UBERON:0000970 ! eye
property_value: UBPROP:0000009 "directing or focusing light onto light receptors" xsd:string

[Term]
id: UBERON:0005396
name: carotid artery segment
namespace: uberon
def: "One of: the common carotid artery, or its branches, the external and internal carotid arteries." [https://sourceforge.net/tracker/?func=detail&aid=3486870&group_id=76834&atid=994764, Wikipedia:Carotid_artery]
subset: efo_slim
subset: grouping_class
subset: pheno_slim
subset: vertebrate_core
synonym: "carotid" EXACT [AAO:0010217]
synonym: "carotid artery" EXACT [MA:0001925]
synonym: "common carotid arterial subdivision" RELATED [FMA:70504]
synonym: "subdivision of common carotid artery" EXACT [FMA:70504]
xref: AAO:0010217
xref: BTO:0000168
xref: CALOHA:TS-0116
xref: EFO:0000818
xref: EHDAA:6385
xref: EMAPA:18609
xref: EV:0100379
xref: FMA:70504
xref: GAID:478
xref: galen:CarotidArtery
xref: MA:0001925
xref: MAT:0000501
xref: MESH:D002339
xref: NCIT:C12687
xref: SCTID:362040006
xref: SCTID:69105007
xref: TAO:0000097
xref: UMLS:C0007272 {source="ncithesaurus:Carotid_Artery"}
xref: VHOG:0000266
xref: Wikipedia:Carotid_artery
xref: ZFA:0000097
is_a: UBERON:0004573 {source="FMA"} ! systemic artery
property_value: editor_note "This is a generic grouping class that is the superclass of the trunks/branches of the common carotid artery. Note that AOs vary widely in how they divide up and generalize arteries" xsd:string
property_value: UBPROP:0000001 "Artery originating at the junction of the first two aortic arches and supplying the anterior brain. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000097", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0005398
name: female reproductive gland
namespace: uberon
def: "A sex gland that is part of a female reproductive system." [OBOL:automatic]
subset: organ_slim
subset: pheno_slim
xref: BTO:0000254
xref: MA:0000383
is_a: UBERON:0003937 ! reproductive gland
intersection_of: UBERON:0003937 ! reproductive gland
intersection_of: part_of UBERON:0000474 ! female reproductive system
relationship: part_of UBERON:0003134 ! female reproductive organ

[Term]
id: UBERON:0005399
name: male reproductive gland
namespace: uberon
def: "A sex gland that is part of a male reproductive system." [OBOL:automatic]
subset: organ_slim
subset: pheno_slim
synonym: "accessory sex gland" RELATED [EMAPA:19285]
xref: BTO:0000080
xref: EMAPA:19285
xref: MA:0000399
is_a: UBERON:0003937 ! reproductive gland
intersection_of: UBERON:0003937 ! reproductive gland
intersection_of: part_of UBERON:0000079 ! male reproductive system
relationship: part_of UBERON:0000079 ! male reproductive system

[Term]
id: UBERON:0005409
name: alimentary part of gastrointestinal system
namespace: uberon
def: "The part of the digestive system that excludes the hepatobiliary system." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "alimentary system" RELATED [MA:0000323]
synonym: "alimentary tract" RELATED [MA:0000323]
synonym: "gastro-intestinal system" RELATED [FMA:71132]
synonym: "gastroenterological system" RELATED [UBERON:cjm]
synonym: "gastrointestinal (GI) tract" RELATED [GAID:294]
synonym: "gastrointestinal system" RELATED [FMA:71132]
synonym: "gastrointestinal tract" RELATED INCONSISTENT [FMA:71132]
synonym: "GI tract" RELATED [GAID:294]
xref: BTO:0000058
xref: CALOHA:TS-0407
xref: EHDAA2:0000110
xref: EHDAA:514
xref: EMAPA:16246
xref: EV:0100056
xref: FMA:71132
xref: GAID:294
xref: galen:GastrointestinalTract
xref: MA:0000323
xref: MESH:D041981
xref: NCIT:C12378
xref: SCTID:373871007
xref: UMLS:C0012240 {source="ncithesaurus:Gastrointestinal_System"}
xref: VHOG:0000412
is_a: UBERON:0000467 ! anatomical system
relationship: existence_ends_during UBERON:0000066 ! fully formed stage
relationship: part_of UBERON:0001007 ! digestive system
property_value: editor_note "the decision to split digestive and gastrointestinal in this way may be revisited. As it currently stands, this class more closely aligns what MA calls the alimentary system" xsd:string
property_value: UBPROP:0000001 "The system that includes the esophagus, stomach, small and large intestine, anus, liver, biliary tract, and pancreas[ncithesaurus:Gastrointestinal_System]." xsd:string {source="ncithesaurus:Gastrointestinal_System"}
property_value: UBPROP:0000003 "All metazoans (with degenerate exceptions) have some sort of digestive cavity with a means of entrance to and exit from it.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000412", ontology="VHOG", source="ISBN:978-0721676685 Sherwood Romer A and Parsons T, Vertebrate body (1977) p.3", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "that many anatomy ontologies consider this synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class. We have one entity that is part of both gastrointestinal and hepatobiliary systems: hepatopancreatic ampulla." xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0005419
name: pectoral appendage bud
namespace: uberon
def: "A limb bud that develops into a forelimb or pectoral fin." [OBOL:automatic]
comment: at this time we have no need to name a more specific 'pectoral fin bud' class, but we may in future
subset: efo_slim
synonym: "forelimb - pectoral fin bud" EXACT [VHOG:0001754]
synonym: "pectoral fin bud" RELATED [TAO:0000141]
synonym: "pectoral fin buds" RELATED OMO:0003004 [TAO:0000141]
xref: EFO:0003430
xref: TAO:0000141
xref: VHOG:0001754
xref: VHOG_RETIRED:0001259
xref: ZFA:0000141
is_a: UBERON:0004357 ! paired limb/fin bud
intersection_of: UBERON:0004357 ! paired limb/fin bud
intersection_of: has_potential_to_develop_into UBERON:0004710 ! pectoral appendage
relationship: has_developmental_contribution_from UBERON:0005729 ! pectoral appendage field
relationship: has_potential_to_develop_into UBERON:0004710 ! pectoral appendage
relationship: part_of UBERON:0000153 ! anterior region of body
property_value: UBPROP:0000001 "Fin bud that develops into the pectoral fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000141", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "While the skeletons of teleost pectoral fins and tetrapod forelimbs are homologous at the level of endoskeletal radials, teleosts and tetrapods do not share homologous skeletal elements at the level of 'individuated' pro-, meso-, and metapterygia. Among osteichthyans, only basal actinopterygians retain the full complement of elements present in non-osteichthyan gnathostomes.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001754", ontology="VHOG", source="DOI:10.1002/jmor.10264 Davis MC, Shubin NH, Force A, Pectoral fin and girdle development in the basal actinopterygians Polyodon spathula and Acipenser transmontanus. Journal of Morphology (2004)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005420
name: pelvic appendage bud
namespace: uberon
def: "A limb bud that develops into a hindlimb or pelvic fin." [OBOL:automatic]
comment: at this time we have no need to name a more specific 'pelvic fin bud' class, but we may in future
subset: efo_slim
synonym: "hindlimb/pelvic fin bud" EXACT [VHOG:0001260]
synonym: "pelvic fin bud" RELATED [TAO:0001384]
synonym: "pelvic fin buds" RELATED OMO:0003004 [ZFA:0001384]
xref: EFO:0003469
xref: TAO:0001384
xref: VHOG:0001260
xref: ZFA:0001384
is_a: UBERON:0004357 ! paired limb/fin bud
intersection_of: UBERON:0004357 ! paired limb/fin bud
intersection_of: has_potential_to_develop_into UBERON:0004709 ! pelvic appendage
intersection_of: part_of UBERON:0000154 ! posterior region of body
relationship: has_developmental_contribution_from UBERON:0005730 ! pelvic appendage field
relationship: has_potential_to_develop_into UBERON:0004709 ! pelvic appendage
relationship: part_of UBERON:0000154 ! posterior region of body
property_value: RO:0002161 NCBITaxon:31033 {source="PMID:15893975"}
property_value: UBPROP:0000001 "Fin bud that develops into the pelvic fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001384", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001260", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005421
name: pectoral appendage apical ectodermal ridge
namespace: uberon
def: "An apical ectodermal ridge that is part of a pectoral appendage bud." [OBOL:automatic]
subset: efo_slim
subset: vertebrate_core
synonym: "AER forelimb" NARROW [VHOG:0001064]
synonym: "aer pectoral fin" RELATED [TAO:0000085]
synonym: "apical ectodermal ridge forelimb" NARROW [VHOG:0001064]
synonym: "apical ectodermal ridge pectoral fin" RELATED [TAO:0000085]
synonym: "apical ectodermal ridge pectoral fin bud" NARROW [ZFA:0000085]
synonym: "apical fold pectoral fin" RELATED [TAO:0000085]
synonym: "upper limb bud apical ectodermal ridge" NARROW [EHDAA2:0000138]
synonym: "wing AER" NARROW SENSU [Giesha:syn]
synonym: "wing apical ectodermal ridge" NARROW SENSU []
xref: EFO:0003487
xref: EHDAA2:0000138
xref: EMAPA:16778
xref: TAO:0000085
xref: TAO:0000736
xref: VHOG:0001064
xref: ZFA:0000085
is_a: UBERON:0004356 ! apical ectodermal ridge
intersection_of: UBERON:0004356 ! apical ectodermal ridge
intersection_of: part_of UBERON:0005419 ! pectoral appendage bud
relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm
relationship: part_of UBERON:0005419 ! pectoral appendage bud
property_value: UBPROP:0000001 "An ectodermal thickening at the end of the forelimb bud in the developing embryo. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001064", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/apical+ectodermal+ridge"}
property_value: UBPROP:0000001 "Apical ectodermal ridge that is part of the pectoral fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000085", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "Pectoral and pelvic fins are homologous to the tetrapod fore and hindlimb, respectively. (...) The zebrafish AER [apical ectodermal ridge] is an apical ectodermal thickening at the distal tip of the fin bud and consists of wedge-shaped cells of the basal stratum. The AER is observed only transiently, and from 36 hpf onwards the cells of this region form the apical fold (AF), which consists of a dorsal and a ventral layer of cylindrically-shaped ectodermal cells extending from the anterior to the posterior fin margin. Despite the change in shape, the AF still carries out the same functions as the AER. Indeed, although the AER receives its name from its characteristic shape, being composed of a pseudostratified ectoderm in the chicken and a polystratified ectoderm in the mouse, this independence of AER morphology from its function is also observed in tetrapods. The AF also expresses similar molecular markers to the tetrapod AER, suggesting that it fulfills similar functions in the fin as the AER does in tetrapod limbs.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001064", ontology="VHOG", source="DOI:10.1111/j.1440-169X.2007.00942.x", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005422
name: pelvic appendage apical ectodermal ridge
namespace: uberon
def: "An apical ectodermal ridge that is part of a pelvic appendage bud." [OBOL:automatic]
subset: efo_slim
subset: vertebrate_core
synonym: "AER hindlimb" RELATED [VHOG:0001066]
synonym: "apical ectodermal ridge hind limb" NARROW [VHOG:0001066]
synonym: "apical ectodermal ridge hindlimb" NARROW [VHOG:0001066]
synonym: "apical ectodermal ridge pelvic fin bud" RELATED [TAO:0001385]
synonym: "leg AER" RELATED []
synonym: "lower lmb bud apical ectodermal ridge" NARROW [EHDAA2:0003194]
xref: EFO:0003681
xref: EHDAA2:0003194
xref: EMAPA:16892
xref: TAO:0001385
xref: VHOG:0001066
xref: ZFA:0001385
is_a: UBERON:0004356 ! apical ectodermal ridge
intersection_of: UBERON:0004356 ! apical ectodermal ridge
intersection_of: part_of UBERON:0005420 ! pelvic appendage bud
relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm
relationship: part_of UBERON:0005420 ! pelvic appendage bud
property_value: UBPROP:0000001 "An ectodermal thickening at the end of the hindlimb bud in the developing embryo. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001066", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/apical+ectodermal+ridge"}
property_value: UBPROP:0000001 "Apical ectodermal ridge that is part of the pelvic fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001385", ontology="TAO", source="ZIFIN:curator"}
property_value: UBPROP:0000003 "Pectoral and pelvic fins are homologous to the tetrapod fore and hindlimb, respectively. (...) The zebrafish AER [apical ectodermal ridge] is an apical ectodermal thickening at the distal tip of the fin bud and consists of wedge-shaped cells of the basal stratum. The AER is observed only transiently, and from 36 hpf onwards the cells of this region form the apical fold (AF), which consists of a dorsal and a ventral layer of cylindrically-shaped ectodermal cells extending from the anterior to the posterior fin margin. Despite the change in shape, the AF still carries out the same functions as the AER. Indeed, although the AER receives its name from its characteristic shape, being composed of a pseudostratified ectoderm in the chicken and a polystratified ectoderm in the mouse, this independence of AER morphology from its function is also observed in tetrapods. The AF also expresses similar molecular markers to the tetrapod AER, suggesting that it fulfills similar functions in the fin as the AER does in tetrapod limbs.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001066", ontology="VHOG", source="DOI:10.1111/j.1440-169X.2007.00942.x", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005423
name: developing anatomical structure
namespace: uberon
subset: common_anatomy
synonym: "developing structure" RELATED []
synonym: "developmental structure" RELATED []
synonym: "developmental tissue" RELATED [MIAA:0000019]
xref: AEO:0000125
xref: CALOHA:TS-2122
xref: EHDAA2:0003125
xref: FBbt:00007006 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:292313
xref: MIAA:0000019
is_a: UBERON:0000465 ! material anatomical entity
relationship: capable_of GO:0032502 ! developmental process
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0005425
name: presumptive neural retina
namespace: uberon
def: "Portion of tissue that is the inner layer of the optic cup and will become the neural retina." [ZFIN:curator]
subset: vertebrate_core
synonym: "future neural epithelium" RELATED [EMAPA:16675]
synonym: "future neural layer" RELATED [EMAPA:16675]
synonym: "future neural retina" EXACT []
synonym: "future NR" RELATED []
synonym: "future retinal neural layer" EXACT []
synonym: "inner layer optic cup" EXACT [ZFA:0001071]
synonym: "optic cup inner layer" EXACT [EHDAA2:0001304]
synonym: "presumptive retina" RELATED [TAO:0001071]
synonym: "presumptive retinas" EXACT OMO:0003004 [ZFA:0001071]
xref: EHDAA2:0001304
xref: EMAPA:16675
xref: TAO:0001071
xref: VHOG:0000490
xref: ZFA:0001071
is_a: UBERON:0006598 ! presumptive structure
is_a: UBERON:0010312 ! immature eye
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0003902 ! retinal neural layer
relationship: has_potential_to_develop_into UBERON:0003902 ! retinal neural layer
relationship: part_of UBERON:0003072 ! optic cup
property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000490", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005426
name: lens vesicle
namespace: uberon
def: "Portion of tissue that gives rise to the lens." [https://sourceforge.net/tracker/?func=detail&atid=994726&aid=3514998&group_id=76834, ZFIN:curator]
subset: pheno_slim
subset: vertebrate_core
synonym: "hollow lens vesicle" NARROW SENSU []
synonym: "immature lens" RELATED [ZFA:0001679]
synonym: "lens mass" RELATED [ZFA:0001679, ZFIN:ZDB-PUB-091023-49]
synonym: "presumptive lens" RELATED [ZFA:0001679]
synonym: "solid lens vesicle" NARROW SENSU [ZFA:0001679]
xref: EHDAA2:0000983
xref: EHDAA:4737
xref: EMAPA:17163
xref: SCTID:361510002
xref: TAO:0002205
xref: VHOG:0001163
xref: ZFA:0001679
is_a: UBERON:0000479 ! tissue
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: develops_from UBERON:0003073 ! lens placode
relationship: has_quality PATO:0001736 {gci_relation="part_of", gci_filler="NCBITaxon:32443", notes="teleosts"} ! solid configuration
relationship: has_quality PATO:0002078 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="Mammals"} ! hollow
property_value: UBPROP:0000001 "A vesicle formed from the lens pit of the embryo, developing into the crystalline lens. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001163", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/lens+vesicle"}
property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The optic cup induces the overlying surface ectoderm first to thicken as a lens placode and then to invaginate and form a lens vesicle that differentiates into the lens.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001163", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "the lens of zebrafish (and other teleosts) forms from delamination of cells from the lens placode; thus, there is no formation of a hollow lens vesicle, in contrast to the situation in mammals and birds (Glass and Dahm, 2004) [PMID:16496288] The lens of the zebrafish forms by delamination of lens placodal cells and not through invagination. This results in a solid spherical mass as opposed to a hollow lens vesicle. Detachment of the solid lens vesicle of zebrafish at 24b26 hpf is accomplished in part by apoptosis, similar to mammals" xsd:string {source="ZFA"}

[Term]
id: UBERON:0005427
name: corneal primordium
namespace: uberon
def: "Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea." [ZFIN:ZDB-PUB-061010-3]
xref: TAO:0002188
xref: ZFA:0001688
is_a: UBERON:0000479 {source="ZFA"} ! tissue
is_a: UBERON:0001048 {source="Obol"} ! primordium
is_a: UBERON:0010312 ! immature eye
is_a: UBERON:0010313 ! neural crest-derived structure
relationship: part_of UBERON:0000019 {source="ZFA"} ! camera-type eye

[Term]
id: UBERON:0005428
name: vagal neural crest
namespace: uberon
def: "Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives[ZFA]." [ZFIN:curator]
subset: vertebrate_core
synonym: "enteric neural crest" RELATED []
synonym: "post-otic neural crest" RELATED [ZFA:0000818]
synonym: "VNC" EXACT OMO:0003000 [XAO:0004191]
xref: EHDAA2:0002156
xref: EHDAA:669
xref: TAO:0000818
xref: VHOG:0001208
xref: XAO:0004191
xref: ZFA:0000818
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
relationship: part_of UBERON:0002342 ! neural crest
property_value: UBPROP:0000001 "Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000818", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001208", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "In chicken fate mapping studies it was found to originate from neural crest residing between Somite 1-7 (S1-7); In mouse it is considered to be derived from rhombencephalic (post otic) neural crest cells and trunk neural crest cells (anterior to S5)" xsd:string {source="filemaps.com"}

[Term]
id: UBERON:0005432
name: aortic sac
namespace: uberon
def: "The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates." [MP:0012510]
subset: pheno_slim
synonym: "saccus aorticus" EXACT OMO:0003011 []
xref: EHDAA2:0004145
xref: EHDAA:9826
xref: EMAPA:36461
xref: FMA:71008
xref: RETIRED_EHDAA2:0000133
xref: SCTID:361527005
is_a: UBERON:0001637 {source="EHDAA2"} ! artery
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0003498 ! heart blood vessel
relationship: develops_from UBERON:0004363 {source="EHDAA2"} ! pharyngeal arch artery
relationship: part_of UBERON:0004145 ! outflow tract
property_value: UBPROP:0000001 "the merged ventral aortae of the embryo which supplies blood to the aortic arches[TMD][http://medical-dictionary.thefreedictionary.com/aortic+sac]." xsd:string {source="http://medical-dictionary.thefreedictionary.com/aortic+sac"}

[Term]
id: UBERON:0005434
name: cervical region
namespace: uberon
synonym: "cervical region" EXACT [FMA:24219]
synonym: "neck subdivision" EXACT [FMA:24219]
synonym: "region of neck" EXACT [FMA:24219]
synonym: "subdivision of neck" EXACT [FMA:24219]
xref: FMA:24219
xref: SCTID:123958008
is_a: UBERON:0011676 ! subdivision of organism along main body axis
relationship: only_in_taxon NCBITaxon:8287 ! Sarcopterygii
relationship: part_of UBERON:0000974 ! neck

[Term]
id: UBERON:0005436
name: common hepatic artery
namespace: uberon
def: "In anatomy, the common hepatic artery is a short blood vessel that supplies oxygenated blood to the liver, pylorus (a part of the stomach), duodenum (a part of the small intestine) and pancreas. It arises from the celiac artery and has the following branches:." [Wikipedia:Common_hepatic_artery]
subset: human_reference_atlas
synonym: "arteria hepatica communis" RELATED OMO:0003011 [Wikipedia:Common_hepatic_artery]
synonym: "common hepatic" RELATED [Wikipedia:Common_hepatic_artery]
xref: EHDAA2:0000308
xref: EHDAA:8570
xref: EMAPA:37206 {source="MA:th"}
xref: FMA:14771
xref: galen:CommonHepaticArtery
xref: MA:0003094
xref: SCTID:244263001
xref: Wikipedia:Common_hepatic_artery
is_a: UBERON:0004573 ! systemic artery
relationship: connecting_branch_of UBERON:0001640 ! celiac artery
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/65/Gray532.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0005446
name: foramen rotundum
namespace: uberon
def: "The foramen rotundum is a circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa." [Wikipedia:Foramen_rotundum]
synonym: "foramen rotundum of the skull" RELATED [Wikipedia:Foramen_rotundum]
synonym: "foramen rotundum ossis sphenoidalis" RELATED OMO:0003011 [Wikipedia:Foramen_rotundum]
synonym: "round foramen" RELATED [VHOG:0001543]
xref: AAO:0000194
xref: EHDAA2:0000552
xref: EHDAA:10629
xref: EMAPA:18712
xref: FMA:53154
xref: SCTID:369439002
xref: VHOG:0001543
xref: Wikipedia:Foramen_rotundum
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0013685 ! foramen of skull
intersection_of: UBERON:0013685 ! foramen of skull
intersection_of: conduit_for UBERON:0000377 ! maxillary nerve
intersection_of: part_of UBERON:0001677 ! sphenoid bone
relationship: conduit_for UBERON:0000377 ! maxillary nerve
relationship: part_of UBERON:0001677 ! sphenoid bone
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/35/Gray145.png" xsd:anyURI
property_value: UBPROP:0000001 "A circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa.vity. [Wikipedia:Foramen_rotundum][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001543", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "It is suggested that the mammalian lamina ascendens arose from an upgrowth of the root of the quadrate ramus of the epipterygoid in cynodonts, separating foramen rotundum from foramen ovale.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001543", ontology="VHOG", source="PMID:1018003 Presley R, Steel FLD, On the homology of the alisphenoid. Journal of Anatomy (1976)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "todo - check placement of AAO class" xsd:string {external_ontology="AAO"}

[Term]
id: UBERON:0005460
name: left vitelline vein
namespace: uberon
def: "A vitelline vein that is in the left side of a multicellular organism." [OBOL:automatic]
xref: EHDAA2:0000971
xref: EMAPA:16380
xref: EMAPA:16698
xref: FMA:70307
xref: SCTID:361446008
is_a: UBERON:0005487 ! vitelline vein
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0005487 ! vitelline vein
intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0005472
name: right vitelline vein
namespace: uberon
def: "A vitelline vein that is in the right side of a multicellular organism." [OBOL:automatic]
xref: EHDAA2:0001766
xref: EMAPA:16381
xref: EMAPA:16699
xref: FMA:70306
xref: SCTID:361445007
is_a: UBERON:0005487 ! vitelline vein
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0005487 ! vitelline vein
intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism
relationship: in_right_side_of UBERON:0000468 ! multicellular organism
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0005478
name: sulcus limitans of neural tube
namespace: uberon
def: "A longitudinal groove in the neural tube wall that divides the neural tube into dorsal (alar) and ventral (basal) halves (dorsal receives input from sensory neurons, ventral effects motor functions); stretches from the mesencephalon caudad[TMD]." [http://medical-dictionary.thefreedictionary.com/Sulcus+limitans, http://www.ncbi.nlm.nih.gov/books/NBK10047]
synonym: "neural tube lateral wall sulcus limitans" EXACT [EHDAA2:0001265]
synonym: "sulcus limitans" BROAD []
xref: BAMS:slim
xref: BAMS:slm
xref: neuronames:629
is_a: UBERON:0006846 ! surface groove
relationship: part_of UBERON:0005496 {source="EHDAA2"} ! neural tube lateral wall

[Term]
id: UBERON:0005487
name: vitelline vein
namespace: uberon
def: "The paired veins that carry blood from the yolk sac back to the embryo." [MGI:csmith, MP:0010666]
subset: pheno_slim
subset: vertebrate_core
synonym: "embryonic vitelline vein" EXACT [VHOG:0000401]
synonym: "omphalomesenteric vein" RELATED [EMAPA:16244]
synonym: "vascular vitelline network" EXACT [XAO:0004147]
synonym: "vein of omphalomesenteric system" RELATED []
synonym: "vena vitellina" EXACT OMO:0003011 [Wikipedia:Vitelline_veins]
synonym: "vitelline veins" RELATED OMO:0003004 [XAO:0004147]
xref: EMAPA:36021
xref: FMA:70305
xref: NCIT:C34329
xref: RETIRED_EHDAA2:0002209
xref: SCTID:2730004
xref: SCTID:308832003
xref: UMLS:C0231091 {source="ncithesaurus:Vitelline_Vein"}
xref: VHOG:0000401
xref: Wikipedia:Vitelline_veins
xref: XAO:0000376
xref: XAO:0004147
is_a: UBERON:0004365 ! vitelline blood vessel
is_a: UBERON:0013140 ! systemic vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0001040 ! yolk sac
relationship: drains UBERON:0001040 ! yolk sac
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray475.png" xsd:anyURI
property_value: UBPROP:0000001 "One of two veins that run upward at first in front, and subsequently on either side of the intestinal canal. They unite on the ventral aspect of the canal, and beyond this are connected to one another by two anastomotic branches, one on the dorsal, and the other on the ventral aspect of the duodenal portion of the intestine, which is thus encircled by two venous rings; into the middle or dorsal anastomosis the superior mesenteric vein opens. The portions of the veins above the upper ring become interrupted by the developing liver and broken up by it into a plexus of small capillary-like vessels termed sinusoids.[XAO]" xsd:string {ontology="XAO", source="XAO:0004147"}
property_value: UBPROP:0000003 "Within each vertebrate group, the veins compose a few main functional systems that arise embryologically from what seems to be a common developmental pattern. (...) Early in development, three major sets of paired veins are present: the vitelline veins from the yolk sac, the cardinal veins from the body of the embryo itself, and the lateral abdominal veins from the pelvic region. The paired vitelline veins are among the first vessels to appear in the embryo. They arise over the yolk and follow the yolk stalk into the body. They then turn anteriorly, continue along the gut, and enter the sinus venosus.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000401", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.460", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "check zfa (no text def). Check vitelline/omphalomesenteric distinction in XAO" xsd:string {external_ontology="XAO"}

[Term]
id: UBERON:0005496
name: neural tube lateral wall
namespace: uberon
def: "Portion of tissue on the side of the lumen of the neural tube." [ZFA:0001435]
subset: vertebrate_core
synonym: "lateral wall neural tube" EXACT [ZFA:0001435]
xref: EHDAA2:0001257
xref: EHDAA:2873
xref: EHDAA:912
xref: EMAPA:16166
xref: TAO:0001435
xref: VHOG:0000513
xref: ZFA:0001435
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: part_of UBERON:0001049 ! neural tube

[Term]
id: UBERON:0005497
name: non-neural ectoderm
namespace: uberon
comment: Gene notes: One of the first genes to be expressed in nonneural ectoderm in amphioxus is BMP2/4 (Panopoulou et al. 1998). BMP2/4 homologues appear to have a very ancient role in distinguishing neural from nonneural ectoderm; in Drosophila as well as in amphioxus and vertebrates, BMP2/4 homologues are expressed in nonneural ectoderm and function in distinguishing neural from nonneural ectoderm (Francois & Bier, 1995 ; Sasai et al. 1995 ; Wilson & Hemmati-Brivanlou, 1995; Panopoulou et al. 1998). A change in level of BMP2/4 from very high in nonneural ectoderm to low in neural ectoderm appears to be a key factor in development of neural crest (Baker & Bronner-Fraser,1997a,1997b;Erickson&Reedy,1998;Marchantet al.1998 ;Selleck et al. 1998).
subset: efo_slim
subset: vertebrate_core
synonym: "epidermal ectoderm" NARROW [https://github.com/obophenotype/uberon/wiki/The-neural-crest]
synonym: "epithelial ectoderm" NARROW [https://github.com/obophenotype/uberon/wiki/The-neural-crest]
synonym: "non neural ectoderm" EXACT [ZFA:0001178]
synonym: "surface ectoderm" RELATED [https://github.com/obophenotype/uberon/wiki/The-neural-crest]
synonym: "ventral ectoderm" RELATED [ZFA:0001178]
xref: EFO:0003643
xref: EHDAA:257
xref: EMAPA:16074
xref: RETIRED_EHDAA2:0001273
xref: TAO:0001178
xref: VHOG:0001372
xref: XAO:0004091
xref: ZFA:0001178
is_a: UBERON:0000479 {source="ZFA"} ! tissue
is_a: UBERON:0004121 ! ectoderm-derived structure
property_value: editor_note "todo - epidermis? todo - track down EHDAA2 class in new release" xsd:string
property_value: RO:0002171 UBERON:0002346
property_value: UBPROP:0000003 "In the early gastrula of vertebrates, factors from the organizer (e.g. noggin, chordin, and follistatin in Xenopus) antagonize the epidermalizing factor bone morphogenetic protein 4 (BMP4), thus dividing the epiblast into neuroectoderm. In Drosophila, decapentaplegic, the homologue of BMP4, interacts similarly with the protein short gastrulation, the homologue of chordin. Thus, a comparable molecular mechanism for distinguishing non-neural ectoderm from neural ectoderm was probably present in the common ancestor of all bilaterally symmetrical animals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001372", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000011 "After gastrulation, neural crest cells are specified at the border of the neural plate and the non-neural ectoderm." xsd:string

[Term]
id: UBERON:0005498
name: primitive heart tube
namespace: uberon
def: "Multi-tissue structure that arises from the heart rudiment and will become the heart tube." [ZFA:0000149]
subset: vertebrate_core
synonym: "early primitive heart tube" NARROW [EMAPA:16208]
synonym: "primitive heart tube" EXACT [EMAPA:16215]
xref: BTO:0006179 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: EHDAA2:0001512
xref: EHDAA:424
xref: EHDAA:436
xref: EMAPA:16215
xref: FMA:321916
xref: SCTID:361522004
xref: TAO:0000149
xref: Wikipedia:Primitive_heart_tube
xref: ZFA:0000149
is_a: UBERON:0000481 ! multi-tissue structure
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: develops_from UBERON:0004291 {source="ZFA"} ! heart rudiment
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000922 ! embryo

[Term]
id: UBERON:0005501
name: rhombomere lateral wall
namespace: uberon
def: "A neural tube lateral wall that is part of a rhombomere." [OBOL:automatic]
synonym: "future hindbrain lateral wall" RELATED [EMAPA:35364]
xref: EMAPA:32819
xref: EMAPA:35364
is_a: UBERON:0005496 ! neural tube lateral wall
intersection_of: UBERON:0005496 ! neural tube lateral wall
intersection_of: part_of UBERON:0001892 ! rhombomere
relationship: part_of UBERON:0001892 ! rhombomere

[Term]
id: UBERON:0005563
name: trigeminal neural crest
namespace: uberon
def: "Cranial neural crest which gives rise to the trigeminal ganglion." [ZFA:0000080]
subset: efo_slim
subset: vertebrate_core
xref: EFO:0003484
xref: EHDAA2:0002083
xref: EHDAA:667
xref: EMAPA:16170
xref: TAO:0000080
xref: VHOG:0000269
xref: ZFA:0000080
is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest
is_a: UBERON:0007213 ! mesenchyme derived from head neural crest
is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population
relationship: part_of UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest
property_value: editor_note "todo - compare ZFA and EHDAA2 representation" xsd:string
property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000269", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005564
name: gonad primordium
namespace: uberon
def: "Portion of tissue that gives rise to the immature gonad." [ZFA:0001262]
subset: efo_slim
subset: grouping_class
subset: vertebrate_core
synonym: "future gonad" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "gonadal primordium" EXACT [ZFA:0001262]
synonym: "immature gonad" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "primitive gonad" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "undifferentiated gonad" EXACT [ZFA:0001262]
xref: EFO:0003651
xref: EHDAA:5927
xref: EMAPA:17204
xref: RETIRED_EHDAA2:0002148
xref: TAO:0001262
xref: WBbt:0008366
xref: ZFA:0001262
is_a: UBERON:0001048 {source="Obol"} ! primordium
relationship: has_potential_to_develop_into UBERON:0000991 ! gonad
relationship: located_in UBERON:0002323 {gci_relation="part_of", gci_filler="NCBITaxon:33511", notes="conservatively place at deuterostome, excluding acoelomates"} ! coelemic cavity lumen
relationship: part_of UBERON:0000990 {source="ZFA"} ! reproductive system
property_value: UBPROP:0000001 "Immature reproductive tissue that has not undergone final maturation into either testis or ovary.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001262", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000008 "this is a very broad grouping class" xsd:string

[Term]
id: UBERON:0005594
name: head somite
namespace: uberon
def: "Somite located in the head region, caudal to the otic vesicle." [PMID:11830559]
synonym: "cranial somite" RELATED [XAO:0000313]
synonym: "occipital somite" EXACT [PMID:11830559, XAO:0000313]
xref: EHDAA2:0003437
xref: EMAPA:16172
xref: XAO:0000313
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0002329 ! somite
is_a: UBERON:0005291 ! embryonic tissue
intersection_of: UBERON:0002329 ! somite
intersection_of: develops_from UBERON:0009617 ! head paraxial mesoderm
relationship: develops_from UBERON:0009617 {source="EHDAA2"} ! head paraxial mesoderm
relationship: part_of UBERON:0009617 {source="EHDAA2"} ! head paraxial mesoderm
property_value: UBPROP:0000008 "in humans this includes somites 1-4" xsd:string
property_value: UBPROP:0000011 "They provide the epaxial and hypaxial muscles of the neck, the pharyngeal and laryngeal muscles that develop in the caudal branchial arches and the musculature of the tongue. Despite their localisation in the head, myogenic precursors from occipital somites essentially follow the trunk programmes (E. H. Walters and S. D., unpublished). during evolution, have been secondarily incorporated into the head (Gans and Northcutt, 1983)" xsd:string {source="PMID:11830559"}
property_value: UBPROP:0000012 "EHDAA2 has both 'head somite' and 'head somite group', with part_of and develops_from for latter" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0005597
name: lung primordium
namespace: uberon
def: "A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum." [XAO:0001002]
subset: efo_slim
synonym: "lateral diverticula" RELATED [XAO:0001002]
synonym: "lung diverticulum" RELATED [AAO:3010717]
synonym: "lung endoderm" RELATED [EFO:0002578]
xref: AAO:0011059
xref: EFO:0002578
xref: EMAPA:36007
xref: XAO:0001002
is_a: UBERON:0001048 {source="XAO"} ! primordium
relationship: develops_from UBERON:0001041 {source="XAO"} ! foregut
relationship: has_potential_to_develop_into UBERON:0000170 ! pair of lungs
relationship: part_of UBERON:0008947 ! respiratory primordium

[Term]
id: UBERON:0005598
name: trunk somite
namespace: uberon
def: "A somite that is part of a trunk." [OBOL:automatic]
xref: AAO:0010385
xref: EHDAA2:0003438
xref: EMAPA:16184
xref: XAO:0000314
is_a: UBERON:0002329 ! somite
intersection_of: UBERON:0002329 ! somite
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk

[Term]
id: UBERON:0005602
name: dorsal mesogastrium
namespace: uberon
def: "The portion of mesentery attached to the greater curvature of the stomach is named the dorsal mesentery (or dorsal mesogastrium, when referring to the portion at the stomach), and the part which suspends the colon is termed the mesocolon. The dorsal mesogastrium develops into the greater omentum." [Wikipedia:Dorsal_mesentery]
synonym: "dorsal mesentery" RELATED [Wikipedia:Dorsal_mesentery]
xref: EHDAA2:0000416
xref: EHDAA:3001
xref: EMAPA:17025
xref: MA:0001618
xref: NCIT:C34142
xref: UMLS:C1512038 {source="ncithesaurus:Dorsal_Mesogastrium"}
xref: VHOG:0000352
xref: Wikipedia:Dorsal_mesentery
is_a: UBERON:0003281 {source="MA"} ! mesentery of stomach
relationship: part_of UBERON:0002296 {source="EHDAA2"} ! dorsal mesentery
relationship: part_of UBERON:0003281 {source="EHDAA2"} ! mesentery of stomach
property_value: UBPROP:0000001 "The dorsal sheet of the primitive mesentery that encloses the stomach. The greater omentum develops from the dorsal mesogastrium. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000352", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/mesogastrium"}

[Term]
id: UBERON:0005604
name: extrahepatic part of hepatic duct
namespace: uberon
synonym: "extrahepatic part of the hepatic duct" EXACT [VHOG:0000215]
synonym: "hepatic duct extrahepatic part" EXACT [MA:0001636]
xref: EMAPA:16844
xref: MA:0001636
xref: VHOG:0000215
is_a: UBERON:0002394 ! bile duct
relationship: part_of UBERON:0003703 {source="MA"} ! extrahepatic bile duct
relationship: part_of UBERON:0005171 {source="MA"} ! hepatic duct

[Term]
id: UBERON:0005610
name: iliac vein
namespace: uberon
def: "Any of the three veins including the common, external and internal iliac veins." [ncithesaurus:Iliac_Vein]
synonym: "pelvic vein" RELATED []
xref: EHDAA2:0000811
xref: EMAPA:37151 {source="MA:th"}
xref: MA:0002142
xref: MESH:D007084
xref: NCIT:C12734
xref: SCTID:281481002
xref: UMLS:C0020888 {source="ncithesaurus:Iliac_Vein"}
is_a: UBERON:0001638 ! vein
relationship: drains UBERON:0010708 ! pectoral complex
relationship: part_of RO:0002577 ! system

[Term]
id: UBERON:0005613
name: left dorsal aorta
namespace: uberon
xref: EHDAA2:0000936
xref: EHDAA:404
xref: EMAPA:16205
xref: MA:0000478
xref: SCTID:361403005
xref: VHOG:0000484
is_a: UBERON:0000947 ! aorta
is_a: UBERON:0003513 ! trunk blood vessel
relationship: part_of UBERON:0005805 ! dorsal aorta
property_value: UBPROP:0000003 "A study of embryos shows that in all vertebrates six arterial arches link the ventral aorta with a pair of lateral dorsal aortae on each side of the body. The latter unite posteriorly to form a single median dorsal aorta wich takes blood to the body.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000484", ontology="VHOG", source="ISBN:978-0174480198 Roberts MBV, Biology: a functional approach (1986) p.572", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "Contributes to the arch of aorta in humans" xsd:string {source="http://emedicine.medscape.com/article/899609-overview"}

[Term]
id: UBERON:0005614
name: lens anterior epithelium
namespace: uberon
def: "A layer of cuboidal epithelial cells bounded anteriorly by the capsule of the lens and posteriorly by the lens cortex." [http://orcid.org/0000-0002-6601-2165]
synonym: "anterior epithelium of lens vesicle" RELATED [EMAPA:17304]
synonym: "anterior surface of lens" RELATED [FMA:58889]
synonym: "lens epithelium" BROAD []
synonym: "lens subcapsular epithelium" EXACT [http://www.lab.anhb.uwa.edu.au/mb140/corepages/eye/eye.htm]
synonym: "subcapsular lens epithelium" EXACT [FMA:70612]
xref: EHDAA2:0000984
xref: EHDAA:9059
xref: EMAPA:17304
xref: EMAPA:17839
xref: FMA:70612
xref: MA:0001302
xref: NCIT:C33641
xref: RETIRED_EHDAA2:0000976
xref: SCTID:362521008
xref: UMLS:C1182652 {source="ncithesaurus:Subcapsular_Epithelium_of_the_Lens"}
xref: VHOG:0001425
is_a: UBERON:0001803 ! epithelium of lens
intersection_of: UBERON:0000483 ! epithelium
intersection_of: adjacent_to UBERON:0001804 ! capsule of lens
intersection_of: part_of UBERON:0000965 ! lens of camera-type eye
relationship: adjacent_to UBERON:0000389 ! lens cortex
relationship: adjacent_to UBERON:0001804 ! capsule of lens
property_value: UBPROP:0000010 "Cells of the subcapsular epithelium (or anterior lens cells) are mitotically active. In adult individuals they only cover the anterior 'hemisphere' of the lens. As they divide, cells gradually move towards the equator of the lens where they tranform into lens fibres. The apical part of the gradually elongating cell extends between the subcapsular epithelium and adjacent lens fibres towards the anterior pole of the lens. The basal part extends towards the posterior pole. The nucleus remains close to the equatorial plane of the lens - http://www.lab.anhb.uwa.edu.au/mb140/corepages/eye/eye.htm" xsd:string

[Term]
id: UBERON:0005616
name: mesenteric artery
namespace: uberon
def: "Arteries which arise from the abdominal aorta and distribute to most of the intestines." [MESH:A07.231.114.565, Wikipedia:Mesenteric_artery]
xref: BTO:0000779
xref: EHDAA2:0001123
xref: EHDAA:4343
xref: EMAPA:17312
xref: MA:0002003
xref: MESH:D008638
xref: NCIT:C52975
xref: SCTID:281084003
xref: UMLS:C0025465 {source="ncithesaurus:Mesenteric_Artery"}
xref: VHOG:0001117
xref: Wikipedia:Mesenteric_artery
xref: XAO:0000370
is_a: UBERON:0012254 ! abdominal aorta artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0000160 ! intestine
relationship: supplies UBERON:0000160 ! intestine
property_value: editor_note "includes posterior and anterior mesenteric arteries, which branch from the dorsal aorta (see Kardong), and superior and inferior mesenteric arteries" xsd:string

[Term]
id: UBERON:0005617
name: mesenteric vein
namespace: uberon
def: "A vein that returns blood from the intestines." [MESH:A07.231.908.670.385, Wikipedia:Mesenteric_vein]
synonym: "intestinal vein" RELATED [http://orcid.org/0000-0002-6601-2165]
xref: BTO:0002781
xref: EHDAA:4442
xref: EMAPA:17348
xref: MA:0002177
xref: MESH:D008642
xref: NCIT:C53055
xref: RETIRED_EHDAA2:0001125
xref: SCTID:304045008
xref: UMLS:C0025473 {source="ncithesaurus:Mesenteric_Vein"}
xref: Wikipedia:Mesenteric_vein
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0000160 ! intestine
relationship: drains UBERON:0000160 ! intestine
relationship: part_of RO:0002577 ! system
property_value: UBPROP:0000008 "In humans the inferior mesenteric vein empties into the splenic vein, the superior mesenteric vein joins the splenic vein to form the portal vein" xsd:string

[Term]
id: UBERON:0005622
name: right dorsal aorta
namespace: uberon
xref: EHDAA2:0001720
xref: EHDAA:406
xref: EMAPA:16206
xref: MA:0000479
xref: SCTID:361404004
xref: VHOG:0000485
is_a: UBERON:0000947 ! aorta
is_a: UBERON:0003513 ! trunk blood vessel
relationship: part_of UBERON:0005805 ! dorsal aorta
property_value: UBPROP:0000003 "A study of embryos shows that in all vertebrates six arterial arches link the ventral aorta with a pair of lateral dorsal aortae on each side of the body. The latter unite posteriorly to form a single median dorsal aorta wich takes blood to the body.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000485", ontology="VHOG", source="ISBN:978-0174480198 Roberts MBV, Biology: a functional approach (1986) p.572", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "Normally regresses in humans" xsd:string {source="http://emedicine.medscape.com/article/899609-overview"}

[Term]
id: UBERON:0005629
name: vascular plexus
namespace: uberon
def: "A vascular network formed by frequent anastomoses between the blood vessels (arteries or veins) of a part." [http://www.medilexicon.com/medicaldictionary.php?t=70052]
synonym: "plexus vasculosus" EXACT OMO:0003011 []
xref: AEO:0000219
xref: EHDAA2:0004112
xref: EMAPA:35904
xref: FMA:5900
xref: XAO:0004143
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0002049 ! vasculature
relationship: has_part UBERON:0001981 ! blood vessel
property_value: UBPROP:0000001 "In a vascular plexus, the contents of the vessels mix. A plexus allows blood to flow via multiple routes. If one branch of the plexus is obstructed, the blood may flow via the open branches[Wikipedia:Plexus#Circulatory_system]." xsd:string {source="Wikipedia:Plexus#Circulatory_system"}

[Term]
id: UBERON:0005631
name: extraembryonic membrane
namespace: uberon
def: "Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo." [ISBN:0073040584]
xref: EHDAA2:0004714
xref: FMA:305915
xref: MESH:D005321 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: SCTID:362840007
is_a: UBERON:0000158 ! membranous layer
relationship: part_of UBERON:0016887 ! entire extraembryonic component
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-extraembryonic-membranes" xsd:anyURI
property_value: UBPROP:0000008 "stuctures homologous to the four extraembryonic membranes appear in mammals [ISBN:0073040584 (Vertebrates, Kardong)]" xsd:string
property_value: UBPROP:0000012 "EHDAA2 is a mereological sum." xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0005637
name: pyloric region epithelium
namespace: uberon
def: "An epithelium that is part of a pylorus." [OBOL:automatic]
xref: EHDAA2:0001582
xref: EMAPA:17633
xref: RETIRED_EHDAA2:0001927
is_a: UBERON:0001276 ! epithelium of stomach
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001166 ! pylorus
relationship: part_of UBERON:0001166 ! pylorus

[Term]
id: UBERON:0005638
name: anterior chamber epithelium
namespace: uberon
def: "An epithelium that is part of a anterior chamber of eyeball." [OBOL:automatic]
xref: EHDAA2:0000130
is_a: UBERON:0015808 ! eye epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001766 ! anterior chamber of eyeball
relationship: part_of UBERON:0001766 ! anterior chamber of eyeball

[Term]
id: UBERON:0005656
name: lens vesicle epithelium
namespace: uberon
def: "An epithelium that is part of a lens vesicle." [OBOL:automatic]
xref: EHDAA2:0000987
xref: EMAPA:17165
xref: VHOG:0000532
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0005426 ! lens vesicle
relationship: part_of UBERON:0005426 ! lens vesicle

[Term]
id: UBERON:0005662
name: 4th arch ectoderm
namespace: uberon
def: "An ectoderm that is part of a pharyngeal arch 4." [OBOL:automatic]
synonym: "4th pharyngeal arch ectoderm" EXACT [VHOG:0001095]
xref: EHDAA2:0004032
xref: EMAPA:16762
xref: EMAPA:16764
xref: EMAPA:16768
xref: RETIRED_EHDAA2:0000094
xref: VHOG:0001095
is_a: UBERON:0000924 ! ectoderm
intersection_of: UBERON:0000924 ! ectoderm
intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4
relationship: part_of UBERON:0003115 ! pharyngeal arch 4
property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001095", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005666
name: 4th arch endoderm
namespace: uberon
def: "An endoderm that is part of a pharyngeal arch 4." [OBOL:automatic]
synonym: "4th pharyngeal arch endoderm" EXACT [VHOG:0001092]
xref: EHDAA2:0004033
xref: EMAPA:16765
xref: EMAPA:16767
xref: EMAPA:16769
xref: RETIRED_EHDAA2:0000095
xref: VHOG:0001092
is_a: UBERON:0000925 ! endoderm
intersection_of: UBERON:0000925 ! endoderm
intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4
relationship: part_of UBERON:0003115 ! pharyngeal arch 4
property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001092", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005667
name: connecting stalk mesoderm
namespace: uberon
xref: EHDAA2:0000314
is_a: UBERON:0003422 ! mesenchyme of umbilical cord
is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue
relationship: develops_from UBERON:0005728 {source="EHDAA2"} ! extraembryonic mesoderm

[Term]
id: UBERON:0005669
name: peritoneal cavity mesothelium
namespace: uberon
def: "A mesothelium that is part of a peritoneal cavity." [OBOL:automatic]
synonym: "mesothelium of peritoneal component" EXACT [EMAPA:16139]
synonym: "mesothelium of peritoneum" EXACT [FMA:18147]
synonym: "peritoneal mesothelium" EXACT [BTO:0003156, EMAPA:16139]
synonym: "peritoneum" BROAD INCONSISTENT [EMAPA:16139]
synonym: "peritoneum mesothelium" EXACT [FMA:18147]
xref: BTO:0003156
xref: EHDAA2:0001447
xref: EMAPA:16139
xref: FMA:18147
xref: SCTID:34073007
is_a: UBERON:0001136 ! mesothelium
intersection_of: UBERON:0001136 ! mesothelium
intersection_of: located_in UBERON:0001179 ! peritoneal cavity
relationship: located_in UBERON:0001179 ! peritoneal cavity
property_value: UBPROP:0000012 "we believe that this corresponds to EMAPA:16139 based on synonyms and parenthood" xsd:string {external_ontology="EMAPA"}

[Term]
id: UBERON:0005672
name: right lung endothelium
namespace: uberon
def: "An endothelium that is part of a right lung." [OBOL:automatic]
xref: EHDAA2:0001755
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0001986 ! endothelium
is_a: UBERON:0003364 ! epithelium of right lung
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0002167 ! right lung

[Term]
id: UBERON:0005673
name: left lung endothelium
namespace: uberon
def: "An endothelium that is part of a left lung." [OBOL:automatic]
xref: EHDAA2:0000961
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0001986 ! endothelium
is_a: UBERON:0003365 ! epithelium of left lung
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0002168 ! left lung

[Term]
id: UBERON:0005685
name: midgut dorsal mesentery
namespace: uberon
def: "A dorsal mesentery that is part of a midgut." [OBOL:automatic]
xref: EMAPA:16722
xref: EMAPA:17040
xref: EMAPA:18671
xref: RETIRED_EHDAA2:0001187
xref: SCTID:361434009
is_a: UBERON:0002296 ! dorsal mesentery
intersection_of: UBERON:0002296 ! dorsal mesentery
intersection_of: part_of UBERON:0001045 ! midgut
relationship: part_of UBERON:0001045 ! midgut

[Term]
id: UBERON:0005688
name: lens vesicle cavity
namespace: uberon
def: "An anatomical cavity that is part of a lens vesicle." [OBOL:automatic]
synonym: "cavity of lens" BROAD []
synonym: "cavity of lens vesicle" EXACT [EMAPA:17164]
synonym: "lens cavity" BROAD [EHDAA2:0000986]
xref: EHDAA2:0000986
xref: EMAPA:17164
xref: VHOG:0000531
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0005426 ! lens vesicle
relationship: luminal_space_of UBERON:0005426 ! lens vesicle
relationship: part_of UBERON:0005426 ! lens vesicle
property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The optic cup induces the overlying surface ectoderm first to thicken as a lens placode and then to invaginate and form a lens vesicle that differentiates into the lens.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000531", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005691
name: 4th arch mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a pharyngeal arch 4." [OBOL:automatic]
synonym: "4th branchial arch mesenchyme" RELATED []
synonym: "4th pharyngeal arch mesenchyme" EXACT [VHOG:0001052]
synonym: "pharyngeal arch 4 mesenchyme" RELATED []
xref: EHDAA2:0000096
xref: EHDAA:1677
xref: EMAPA:16770
xref: FMA:295702
xref: VHOG:0001052
is_a: UBERON:0009494 ! pharyngeal arch mesenchymal region
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4
relationship: part_of UBERON:0003115 ! pharyngeal arch 4
property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001052", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005702
name: optic eminence mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a optic eminence." [OBOL:automatic]
xref: EHDAA:942
xref: EMAPA:16324
xref: RETIRED_EHDAA2:0001310
xref: VHOG:0001073
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0005291 ! embryonic tissue
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0004348 ! optic eminence
relationship: part_of UBERON:0004348 ! optic eminence

[Term]
id: UBERON:0005711
name: foregut duodenum mesentery
namespace: uberon
def: "A mesentery of duodenum that is part of a foregut." [OBOL:automatic]
xref: EHDAA2:0000564
is_a: UBERON:0003397 ! mesentery of duodenum
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0003397 ! mesentery of duodenum
intersection_of: part_of UBERON:0001041 ! foregut
relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm
relationship: part_of UBERON:0001041 ! foregut

[Term]
id: UBERON:0005712
name: midgut duodenum mesentery
namespace: uberon
def: "A mesentery of duodenum that is part of a midgut." [OBOL:automatic]
xref: EHDAA2:0001193
is_a: UBERON:0003284 ! mesentery of midgut
is_a: UBERON:0003397 ! mesentery of duodenum
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0003397 ! mesentery of duodenum
intersection_of: part_of UBERON:0001045 ! midgut
relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm

[Term]
id: UBERON:0005720
name: hindbrain venous system
namespace: uberon
def: "A venous system that is part of a hindbrain." [OBOL:automatic]
synonym: "rhombencephalon venous system" RELATED [VHOG:0001322]
xref: EHDAA2:0000776
xref: EMAPA:18632
xref: VHOG:0001322
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0004582 ! venous system
intersection_of: UBERON:0004582 ! venous system
intersection_of: part_of UBERON:0002028 ! hindbrain
relationship: part_of UBERON:0002028 ! hindbrain

[Term]
id: UBERON:0005721
name: pronephric mesoderm
namespace: uberon
def: "A mesoderm that has the potential to develop into a pronephros." [OBOL:automatic]
comment: the intermediate mesoderm of the chick embryo acquires its ability to form kidneys through its interactions with the paraxial mesoderm [ISBN:9780878932504 "Developmental Biology", PMID:10720431 "Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm"]. These interactions induce the expression of TFs including Lim1, Pax2 and Pax6 that cause the intermediate mesoderm to form the kidney
subset: efo_slim
synonym: "pronephric anlage" RELATED [XAO:0000264]
synonym: "pronephric bulge" RELATED [XAO:0000264]
synonym: "pronephric mesenchyme" RELATED [XAO:0000264]
synonym: "pronephric primordium" RELATED [XAO:0000264]
xref: AAO:0011090
xref: EFO:0003479
xref: TAO:0000067
xref: VHOG:0001239
xref: XAO:0000264
xref: ZFA:0000067
is_a: UBERON:0000926 ! mesoderm
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0000926 ! mesoderm
intersection_of: has_potential_to_develop_into UBERON:0002120 ! pronephros
relationship: develops_from UBERON:0007297 ! presumptive pronephric mesoderm
relationship: has_potential_to_develop_into UBERON:0002120 ! pronephros
relationship: immediate_transformation_of UBERON:0007297 {source="Bgee:AN"} ! presumptive pronephric mesoderm
relationship: part_of UBERON:0003064 {source="ZFA"} ! intermediate mesoderm
property_value: UBPROP:0000001 "Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011090", ontology="AAO", source="XAO:curator"}

[Term]
id: UBERON:0005726
name: chemosensory system
namespace: uberon
subset: functional_classification
xref: BILA:0000139
is_a: UBERON:0001032 ! sensory system
intersection_of: UBERON:0001032 ! sensory system
intersection_of: capable_of GO:0007606 ! sensory perception of chemical stimulus
relationship: capable_of GO:0007606 ! sensory perception of chemical stimulus

[Term]
id: UBERON:0005728
name: extraembryonic mesoderm
namespace: uberon
synonym: "extra-embryonic mesoderm" EXACT []
synonym: "extraembryonic mesenchyme" EXACT []
xref: EHDAA2:0000474
xref: EMAPA:31862
xref: EMAPA:31863
xref: FMA:296719
xref: VHOG:0000616
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005292 ! extraembryonic tissue
is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue
relationship: develops_from UBERON:0003081 ! lateral plate mesoderm
relationship: develops_from UBERON:0008780 {source="EHDAA2"} ! inner cell mass derived epiblast

[Term]
id: UBERON:0005729
name: pectoral appendage field
namespace: uberon
def: "A limb/fin field that has the potential to develop into a pectoral appendage bud mesenchyme." [OBOL:automatic]
synonym: "pectoral appendage field of lateral plate mesoderm" EXACT []
synonym: "pectoral fin field" NARROW SENSU [ZFA:0001453]
xref: TAO:0001453
xref: ZFA:0001453
is_a: UBERON:0005732 ! paired limb/fin field
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0005732 ! paired limb/fin field
intersection_of: has_potential_to_develop_into UBERON:0003413 ! pectoral appendage bud mesenchyme
relationship: has_potential_to_develop_into UBERON:0003413 ! pectoral appendage bud mesenchyme
property_value: UBPROP:0000001 "Embryonic region that develops into the pectoral fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001453", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0005730
name: pelvic appendage field
namespace: uberon
def: "A limb/fin field that has the potential to develop into a pelvic appendage bud mesenchyme." [OBOL:automatic]
synonym: "pelvic appendage field of lateral plate mesoderm" EXACT []
synonym: "pelvic fin field" NARROW SENSU [ZFA:0001454]
xref: TAO:0001454
xref: ZFA:0001454
is_a: UBERON:0005732 ! paired limb/fin field
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0005732 ! paired limb/fin field
intersection_of: has_potential_to_develop_into UBERON:0003412 ! pelvic appendage bud mesenchyme
relationship: has_potential_to_develop_into UBERON:0003412 ! pelvic appendage bud mesenchyme
property_value: UBPROP:0000001 "Embryonic region that develops into the pelvic fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001454", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0005732
name: paired limb/fin field
namespace: uberon
def: "A ring of cells capable of forming a limb or paired fin[Gilbert,modified]." [ISBN:9780878932504]
subset: homology_grouping
synonym: "limb/fin field of lateral plate mesoderm" EXACT []
synonym: "paired limb/fin field" EXACT []
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007688 ! anlage
intersection_of: UBERON:0007688 ! anlage
intersection_of: has_potential_to_developmentally_contribute_to UBERON:0004357 ! paired limb/fin bud
relationship: has_potential_to_developmentally_contribute_to UBERON:0004357 ! paired limb/fin bud
relationship: part_of UBERON:0003081 {source="ISBN:9780878932504", source="ZFA-inferred"} ! lateral plate mesoderm
property_value: editor_note "we represent the field as being a part of the LPM (consistent with ZFA, Gilbert). As a consequence, the relationship between limb bud (with is ectoderm+mesenchyme) stands in a weaker has_developmental_contribution_from relation to the field - TODO implement this." xsd:string

[Term]
id: UBERON:0005734
name: tunica adventitia of blood vessel
namespace: uberon
def: "The outermost layer of a blood vessel, composed mainly of fibrous tissue." [ISBN:0073040584, Wikipedia:Tunica_externa_(vessels)]
synonym: "adventitia externa" EXACT [Wikipedia:Tunica_externa_(vessels)]
synonym: "external coat" RELATED [Wikipedia:Tunica_externa_(vessels)]
synonym: "tunica adventitia" EXACT [Wikipedia:Tunica_externa_(vessels)]
synonym: "tunica adventitia of vessel" EXACT [Wikipedia:Tunica_externa_(vessels)]
synonym: "tunica adventitia vasorum" RELATED OMO:0003011 [Wikipedia:Tunica_externa_(vessels)]
synonym: "tunica externa vasorum" RELATED OMO:0003011 [Wikipedia:Tunica_externa_(vessels)]
xref: BTO:0002010
xref: EMAPA:36299
xref: NCIT:C33818
xref: SCTID:61066005
xref: UMLS:C0225342 {source="ncithesaurus:Tunica_Adventitia"}
xref: Wikipedia:Tunica_externa_(vessels)
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004797 {source="cjm"} ! blood vessel layer
is_a: UBERON:0005742 ! adventitia
relationship: composed_primarily_of UBERON:0011824 ! fibrous connective tissue
relationship: has_quality PATO:0002462 ! collagenous
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg" xsd:anyURI
property_value: editor_note "TODO - note terminological problems. WP says tunica external layer of blood vessel. FMA says tunica externa = adventitia, and is FMA adventitia covers other kinds of vessels. Here we opt for a lengthier name that attempts to disambiguate. There is no precise FMA equivalent, as FMA has tunica externa of arteries, veins, genital ducts etc as siblings" xsd:string
property_value: UBPROP:0000001 "The outermost layer of a blood vessel, surrounding the tunica media. It is mainly composed of collagen. The collagen serves to anchor the blood vessel to nearby organs, giving it stability[Wikipedia:Tunica_externa_(vessels)]." xsd:string {source="Wikipedia:Tunica_externa_(vessels)"}

[Term]
id: UBERON:0005740
name: tunica intima of artery
namespace: uberon
def: "A tunica intima that is part of a artery." [OBOL:automatic]
synonym: "arterial intima" EXACT [EV:0100028]
synonym: "tunica interna (intima)(arteriae)" EXACT [FMA:14272]
xref: EMAPA:36293
xref: EV:0100028
xref: FMA:14272
xref: galen:IntimaOfArtery
xref: SCTID:40022005
is_a: UBERON:0002523 ! tunica intima
is_a: UBERON:0004797 ! blood vessel layer
intersection_of: UBERON:0002523 ! tunica intima
intersection_of: part_of UBERON:0001637 ! artery
relationship: part_of UBERON:0000415 ! artery wall

[Term]
id: UBERON:0005742
name: adventitia
namespace: uberon
def: "An outermost connective tissue covering of an organ, vessel, or other structure[WP]." [Wikipedia:Adventitia]
subset: grouping_class
subset: human_reference_atlas
synonym: "tunica advetitia" NARROW [Wikipedia:Adventitia]
synonym: "tunica externa" NARROW [FMA:45635]
xref: BTO:0002010
xref: FMA:45635
xref: MESH:D063194 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: SCTID:30180000
xref: Wikipedia:Adventitia
is_a: UBERON:0004923 ! organ component layer
relationship: composed_primarily_of UBERON:0002384 ! connective tissue
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e8/Illu_esophageal_layers.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0005744
name: bone foramen
namespace: uberon
def: "Anatomical space that is an opening in a bone, usually for passage of blood vessels or nerves." [TAO:curator]
subset: vertebrate_core
synonym: "foramen" BROAD [ZFA:0005386]
xref: AAO:0010438
xref: TAO:0001736
xref: VHOG:0001760
xref: ZFA:0005386
is_a: UBERON:0004111 ! anatomical conduit
intersection_of: UBERON:0004111 ! anatomical conduit
intersection_of: part_of UBERON:0001474 ! bone element
relationship: part_of UBERON:0001474 ! bone element
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray193.png" xsd:anyURI
property_value: UBPROP:0000012 "in FMA and ZFA this is a conduit space, not a conduit. Note there may be some additional disambiguation required: foramen is used loosely in the sense of any opening (e.g. foramen primum). FMA appears to use cranial conduit (undefined) in the sense of any foramen of the skull (includes mental foramen, which is not in the cranium proper)." xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0005753
name: caudal part of nephrogenic cord
namespace: uberon
def: "The metanephros develops from the most caudal part of the nephrogenic cord that is itself derived from the intermediate plate mesoderm." [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron]
synonym: "caudal portion of nephrogenic cord" EXACT [OBOL:automatic]
synonym: "caudal region of nephrogenic cord" EXACT [OBOL:automatic]
synonym: "rear part of nephrogenic cord" EXACT [OBOL:automatic]
synonym: "rear portion of nephrogenic cord" EXACT [Wikipedia:Metanephros#Metanephros]
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0004875 ! nephrogenic cord

[Term]
id: UBERON:0005754
name: rostral part of nephrogenic cord
namespace: uberon
def: "The initial renal anlage that develops from the most rostral part of the nephrogenic cord is termed the pronephros." [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron]
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0004875 ! nephrogenic cord

[Term]
id: UBERON:0005764
name: acellular membrane
namespace: uberon
def: "An acellular anatomical structure that is the bounding layer of a anatomical structure." [OBOL:automatic]
subset: common_anatomy
xref: FMA:63871
is_a: UBERON:0000476 ! acellular anatomical structure
intersection_of: UBERON:0000476 ! acellular anatomical structure
intersection_of: bounding_layer_of UBERON:0000061 ! anatomical structure
relationship: bounding_layer_of UBERON:0000061 ! anatomical structure
relationship: part_of UBERON:0000061 ! anatomical structure
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0005769
name: basement membrane of epithelium
namespace: uberon
def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane]
synonym: "basement membrane" RELATED [FMA:63872]
synonym: "basement membrane of connective tissue" EXACT [FMA:63872]
synonym: "membrana basalis" EXACT OMO:0003011 [Wikipedia:Basement_membrane]
xref: AAO:0010596
xref: FMA:63872
xref: GAID:915
xref: NCIT:C13191
xref: SCTID:68989006
xref: UMLS:C0004799 {source="ncithesaurus:Basement_Membrane"}
xref: Wikipedia:Basement_membrane
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0005764 {source="FMA"} ! acellular membrane
relationship: adjacent_to CL:0000066 ! epithelial cell
relationship: composed_primarily_of GO:0005604 ! basement membrane
relationship: has_part GO:0005587 ! collagen type IV trimer
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of UBERON:0000483 ! epithelium
property_value: curator_notes "this class represents a continuous sheet of basement membrane which can underlie multiple epithelial cells over large regions. In contrast, the GO class 'basal membrane' represents a portion of substance on the scale of a single cell." xsd:string
property_value: RO:0002175 NCBITaxon:80999 {source="http://palaeos.com/metazoa/porifera/homoscleromorpha.html"}

[Term]
id: UBERON:0005792
name: nephric ridge
namespace: uberon
def: "Nephric tubules (nephrons) form embryonically along the nephric ridge. The ridge comprises three regions; anterior, middle and posterior. The functional kidney uses nephrons from only one or two regions of the ridge. A pronephric kidney uses only the nephrons from the anterior region of the ridge. A mesonephric kidney uses only the middle region, a metanephric kidney uses only the posterior region and an opisthonephric kidney uses the middle and posterior regions." [http://cwx.prenhall.com/bookbind/pubbooks/martini10/chapter27/custom2/deluxe-content.html]
synonym: "nephric cord" RELATED [VHOG:0001240]
xref: EHDAA2:0001242
xref: EHDAA:1015
xref: EMAPA:16368
xref: VHOG:0001240
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0001008 ! renal system
relationship: part_of UBERON:0004122 ! genitourinary system
property_value: editor_note "TODO - check ridge vs cord vs nephrogenic cord vs blastema" xsd:string

[Term]
id: UBERON:0005795
name: embryonic uterus
namespace: uberon
synonym: "fetal uterus" EXACT [FMA:72173]
xref: FMA:72173
xref: SCTID:255782009
is_a: UBERON:0006598 ! presumptive structure
relationship: has_potential_to_develop_into UBERON:0000995 ! uterus

[Term]
id: UBERON:0005800
name: section of aorta
namespace: uberon
def: "Any portion of the aorta including the ascending and descending aorta, and aortic arch or a portion of the aortic orifice of the left ventricle." [ncithesaurus:Aortic_Segment]
synonym: "aortic section" EXACT []
synonym: "aortic segment" RELATED [FMA:13087]
synonym: "portion of aorta" RELATED []
synonym: "segment of aorta" RELATED [FMA:13087]
xref: FMA:13087
xref: NCIT:C34027
xref: SCTID:119203005
xref: UMLS:C0506947 {source="ncithesaurus:Aortic_Segment"}
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0013522 ! subdivision of tube
relationship: part_of UBERON:0000947 ! aorta

[Term]
id: UBERON:0005805
name: dorsal aorta
namespace: uberon
def: "The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GO:0035907, https://sourceforge.net/p/geneontology/ontology-requests/8525/]
subset: vertebrate_core
synonym: "aorta dorsalis" EXACT OMO:0003011 [XAO:0000051]
synonym: "aortae dorsales" RELATED OMO:0003011 [Wikipedia:Dorsal_aorta]
synonym: "DA" EXACT [ZFA:0000014]
synonym: "dorsal aorta root" RELATED [VHOG:0000264]
synonym: "dorsal aortae" RELATED OMO:0003004 [Wikipedia:Dorsal_aorta]
synonym: "dorsal aortic root" RELATED [VHOG:0000264]
synonym: "dorsal aortæ" RELATED OMO:0003004 [Wikipedia:Dorsal_aorta]
xref: AAO:0011029
xref: BTO:0004673
xref: EHDAA:402
xref: EMAPA:18606
xref: SCTID:338637006
xref: TAO:0000014
xref: VHOG:0000264
xref: Wikipedia:Dorsal_aorta
xref: XAO:0000051
xref: ZFA:0000014
is_a: UBERON:0000947 ! aorta
is_a: UBERON:0003513 ! trunk blood vessel
relationship: develops_from UBERON:0001917 ! endothelium of artery
relationship: develops_from UBERON:0003064 ! intermediate mesoderm
relationship: part_of UBERON:0002201 ! vasculature of trunk
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray459.png" xsd:anyURI
property_value: UBPROP:0000001 "Each primitive aorta receives anteriorly a vein 'the vitelline vein' from the yolk-sac, and is prolonged backward on the lateral aspect of the notochord under the name of the dorsal aorta. The dorsal aortae give branches to the yolk-sac, and are continued backward through the body-stalk as the umbilical arteries to the villi of the chorion. The two dorsal aortae combine to become the descending aorta in later development[WP]." xsd:string {source="Wikipedia:Dorsal_aorta"}
property_value: UBPROP:0000001 "Principal unpaired, median artery of the trunk, leading from the paired roots (radices) of the dorsal aorta to the caudal artery. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000014", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "The artery in vertebrate embryos that transports blood from the aortic arches to the trunk and limbs. In adult fish it is a major artery that carries oxygenated blood from the efferent branchial arteries to branches that supply the body organ. In adult tetrapods it arises from the systemic arch" xsd:string {source="BTO:0004673"}
property_value: UBPROP:0000002 "relationship loss: part_of axial vasculature (TAO:0001073)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000014", ontology="TAO"}
property_value: UBPROP:0000003 "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000264", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0005806
name: portal system
namespace: uberon
def: "In the circulatory system of animals, a portal venous system occurs when a capillary bed drains into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. They are relatively uncommon as the majority of capillary beds drain into veins which then drain into the heart, not into another capillary bed. Portal venous systems are considered venous because the blood vessels that join the two capillary beds are either veins or venules. Examples of such systems include the hepatic portal system and the hypophyseal portal system. Unqualified, 'portal venous system' often refers to the hepatic portal system. For this reason, 'portal vein' most commonly refers to the hepatic portal vein[WP]." [Wikipedia:Portal_venous_system]
synonym: "portal venous system" EXACT [FMA:45628]
xref: FMA:45628
xref: MESH:D011168
xref: NCIT:C33344
xref: SCTID:362063001
xref: UMLS:C0226727 {source="ncithesaurus:Portal_Venous_System"}
xref: Wikipedia:Portal_venous_system
is_a: UBERON:0002049 ! vasculature

[Term]
id: UBERON:0005844
name: spinal cord segment
namespace: uberon
synonym: "axial part of spinal cord" EXACT [BIRNLEX:2665]
synonym: "axial regional part of spinal cord" EXACT [BIRNLEX:2665]
synonym: "segment of spinal cord" EXACT [FMA:62420]
synonym: "spinal neuromeres" RELATED OMO:0003004 [TAO:0001332]
xref: BIRNLEX:2665
xref: FMA:62420
xref: MA:0003080
xref: SCTID:278748001
is_a: UBERON:0001948 ! regional part of spinal cord
property_value: editor_note "This is currently used loosely to refer to cervical, lumbar, etc as well as the metamerically repeated segments, which may correspond more closely with the ZFA neuromere term" xsd:string

[Term]
id: UBERON:0005845
name: caudal segment of spinal cord
namespace: uberon
def: "A spinal cord segment that adjacent_to a caudal region." [OBOL:automatic]
comment: for spinal cord segments, we treat coccygeal/caudal as synonyms - we only differentiate where bone is concerned
synonym: "coccygeal segment of spinal cord" EXACT [FMA:256635]
synonym: "coccygeal segments of spinal cord [1-3]" EXACT [FMA:256635]
synonym: "pars coccygea medullae spinalis" EXACT OMO:0003011 [FMA:256635, FMA:TA]
synonym: "segmenta coccygea" RELATED OMO:0003011 [NeuroNames:1656]
synonym: "segmenta coccygea medullae spinalis [1-3]" EXACT OMO:0003011 [FMA:256635, FMA:TA]
xref: FMA:256635
xref: MA:0003084
xref: neuronames:1656
xref: SCTID:278753006
is_a: UBERON:0005844 ! spinal cord segment
intersection_of: UBERON:0005844 ! spinal cord segment
intersection_of: adjacent_to UBERON:0006071 ! caudal region
relationship: adjacent_to UBERON:0006071 ! caudal region

[Term]
id: UBERON:0005856
name: developing mesenchymal condensation
namespace: uberon
def: "A delimited region of dense mesenchyme within looser mesenchyme." [AEO:0000148]
synonym: "mesenchyme condensation" EXACT [EMAPA:25351]
xref: AEO:0000148
xref: EHDAA2_RETIRED:0003148
xref: EHDAA:8979
is_a: UBERON:0007524 {source="AEO"} ! dense mesenchyme tissue
is_a: UBERON:0011585 {source="cjm"} ! cell condensation
relationship: composed_primarily_of CL:0000335 {source="AEO-modified-relation"} ! mesenchyme condensation cell

[Term]
id: UBERON:0005863
name: cartilaginous condensation
namespace: uberon
def: "Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes." [GO:curator]
synonym: "cartilage condensation" EXACT [EMAPA:25353]
synonym: "cartilagenous condensation" EXACT [EHDAA2:0003147]
synonym: "chondrogenic condensation" EXACT [VSAO:0000092]
xref: AEO:0000147
xref: EHDAA2_RETIRED:0003147
xref: EMAPA:32731
xref: VSAO:0000092
xref: XAO:0004022
is_a: UBERON:0005856 {source="AEO"} ! developing mesenchymal condensation
relationship: develops_from UBERON:0005866 ! pre-cartilage condensation
relationship: part_of UBERON:0004288 {source="AEO"} ! skeleton
property_value: UBPROP:0000012 "isa cell condensation in VSAO; has_part chondroblast in AEO" xsd:string {external_ontology="VSAO"}

[Term]
id: UBERON:0005865
name: pre-muscle condensation
namespace: uberon
alt_id: UBERON:0008714
synonym: "pre muscle mass" EXACT []
synonym: "premuscle mass" EXACT []
xref: AEO:0000149
xref: EHDAA2_RETIRED:0003149
is_a: UBERON:0005856 ! developing mesenchymal condensation
intersection_of: UBERON:0005856 ! developing mesenchymal condensation
intersection_of: composed_primarily_of CL:0000680 ! muscle precursor cell
relationship: composed_primarily_of CL:0000680 ! muscle precursor cell
relationship: has_part CL:0000680 {source="AEO"} ! muscle precursor cell
relationship: has_potential_to_develop_into UBERON:0005090 ! muscle structure

[Term]
id: UBERON:0005866
name: pre-cartilage condensation
namespace: uberon
def: "A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts." [AEO:0000150, AEO:JB]
synonym: "pre-chondrogenic condensation" EXACT []
synonym: "precartilage condensation" EXACT []
synonym: "precartilagenous condensation" EXACT []
synonym: "prechondrogenic condensation" EXACT []
xref: AEO:0000150
xref: EHDAA2:0003150
xref: EMAPA:32736
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0005856 {source="AEO"} ! developing mesenchymal condensation
relationship: has_potential_to_develop_into UBERON:0007844 ! cartilage element
relationship: part_of UBERON:0004288 {source="AEO"} ! skeleton
property_value: UBPROP:0000001 "A closely packed aggregation of mesenchymal cells just prior to their differentiation into embryonic cartilage." xsd:string {source="http://dictionary.reference.com/browse/precartilage"}

[Term]
id: UBERON:0005867
name: mandibular prominence
namespace: uberon
def: "The paired ventral prominences formed by bifurcation of the first pharyngeal arches in the embryo; the two prominences unite ventrally and fuse to form the mandible and lower lip." [ISBN:0-683-40008-8, MP:0010939]
subset: pheno_slim
synonym: "mandibular process" RELATED [Wikipedia:Mandibular_prominence]
synonym: "mandibular swelling" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "prominentia mandibularis" RELATED OMO:0003011 [Wikipedia:Mandibular_prominence]
xref: EHDAA2:0001061
xref: EHDAA:5871
xref: EMAPA:17355
xref: FMA:293051
xref: NCIT:C34204
xref: UMLS:C1512982 {source="ncithesaurus:Mandibular_Prominence"}
xref: Wikipedia:Mandibular_prominence
is_a: UBERON:0012314 ! embryonic facial prominence
relationship: develops_from UBERON:0007237 ! 1st arch mandibular component
relationship: part_of UBERON:0000166 ! oral opening
property_value: editor_note "check develops_from" xsd:string

[Term]
id: UBERON:0005868
name: maxillary prominence
namespace: uberon
def: "The paired dorsal prominences formed by bifurcation of the first pharyngeal arches in the embryo that unite with the ipsilateral medial nasal process to form the upper jaw." [ISBN:0-683-40008-8, MP:0010940]
subset: pheno_slim
synonym: "embryonic maxillary process" EXACT []
synonym: "maxillary process" EXACT [EHDAA2:0001070]
synonym: "maxillary process of embryo" EXACT []
synonym: "prominentia maxilaris" RELATED OMO:0003011 [Wikipedia:Maxillary_prominence]
xref: EHDAA2:0001070
xref: EHDAA:5877
xref: EMAPA:17359
xref: FMA:293049
xref: NCIT:C34206
xref: SCTID:346355001
xref: UMLS:C1513037 {source="ncithesaurus:Maxillary_Prominence"}
xref: Wikipedia:Maxillary_prominence
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0007238 ! 1st arch maxillary component
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray48.png" xsd:anyURI

[Term]
id: UBERON:0005876
name: undifferentiated genital tubercle
namespace: uberon
def: "The embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin." [https://github.com/obophenotype/uberon/issues/1230, MGI:anna, MP:0011771]
subset: pheno_slim
synonym: "genital tubercle" RELATED [EMAPA:17382]
synonym: "phallic tubercle" RELATED []
synonym: "tuberculum genitale" RELATED OMO:0003011 [Wikipedia:Genital_tubercle]
synonym: "tuberculum phallicum" RELATED OMO:0003011 [Wikipedia:Genital_tubercle]
synonym: "undifferentiated genital tubercle" EXACT [VHOG:0000583]
xref: EHDAA2:0000705
xref: EHDAA:5925
xref: EMAPA:17382
xref: FMA:302888
xref: SCTID:308798005
xref: VHOG:0000583
xref: Wikipedia:Genital_tubercle
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0004874 ! somatopleure
relationship: has_potential_to_develop_into UBERON:0011757 ! differentiated genital tubercle
relationship: only_in_taxon NCBITaxon:32524 {source="https://github.com/obophenotype/uberon/issues/1230"} ! Amniota
relationship: part_of UBERON:0009196 {source="EHDAA2"} ! indifferent external genitalia
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray1119.png" xsd:anyURI
property_value: UBPROP:0000001 "embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin; GT development is indistinguishable in male and female mouse embryos until ~E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP]" xsd:string {ontology="MP"}
property_value: UBPROP:0000001 "The eminence in the embryo which develops into the clitoris or penis. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000583", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/genital+tubercle"}
property_value: UBPROP:0000003 "In mammalian embryos, male and female external genitalia develop from the genital tubercle.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000583", ontology="VHOG", source="DOI:10.1242/dev.036830 Seifert AW, Yamaguchi T, Cohn MJ, Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital development. Development (2009)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000008 "All amniotes studied to date initiate external genital development with the formation of paired genital swellings. In mammals, archosaurs, and turtles, these swellings merge to form a single genital tubercle, the precursor of the penis and clitoris[PMID:24960313]" xsd:string
property_value: UBPROP:0000008 "GT development is indistinguishable in male and female mouse embryos until approximately E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP:0011771]" xsd:string
property_value: UBPROP:0000008 "todo - add taxon constraints" xsd:string
property_value: UBPROP:0000012 "we assume the EMAPA class is the undifferentiated form based on TS timings" xsd:string {external_ontology="EMAPA"}

[Term]
id: UBERON:0005891
name: coelomic epithelium
namespace: uberon
def: "The epithelial lining of the surface of the coelom." [Wikipedia:Coelomic_epithelium, XAO:0000329]
synonym: "celomic epithelium" EXACT []
synonym: "germinal epithelium of Waldeyer" EXACT [Wikipedia:Coelomic_epithelium]
xref: Wikipedia:Coelomic_epithelium
xref: XAO:0000329
is_a: UBERON:0000483 ! epithelium
relationship: has_developmental_contribution_from UBERON:0004871 {source="XAO"} ! somatic layer of lateral plate mesoderm
relationship: has_developmental_contribution_from UBERON:0004872 {source="XAO"} ! splanchnic layer of lateral plate mesoderm
relationship: located_in UBERON:0002323 ! coelemic cavity lumen
relationship: part_of UBERON:0011997 ! coelom
property_value: UBPROP:0000012 "EHDAA2:0004049 used to be called 'coelomic epithelium' but is now 'gonadal ridge mesothelium'" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0005902
name: occipital region
namespace: uberon
def: "Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles." [TAO:0001414, UBERONREF:0000007]
synonym: "back of head" RELATED [FMA:49187]
synonym: "basicranial region" EXACT [ZFA:0001414]
synonym: "occipital part of head" EXACT [FMA:49187]
synonym: "occipital region of head" EXACT [FMA:49187]
xref: AAO:0010199
xref: BTO:0004675
xref: FMA:49187
xref: MESH:D009778 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: neuronames:2431
xref: SCTID:362618001
xref: TAO:0001414
xref: XAO:0003173
xref: ZFA:0001414
is_a: UBERON:0034921 ! multi organ part structure
relationship: part_of UBERON:0003128 ! cranium
property_value: editor_note "TODO - check" xsd:string
property_value: UBPROP:0000001 "An anatomical cluster that is located in the posterior region of the neurocranium and forms the margin of the foramen margin and occipital condyles.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010199", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occiptal condyle.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001414", ontology="TAO", source="TAO:MAH"}

[Term]
id: UBERON:0005903
name: duct of seminal vesicle
namespace: uberon
def: "Each seminal vesicle consists of a single tube, coiled upon itself, and giving off several irregular cecal diverticula; the separate coils, as well as the diverticula, are connected together by fibrous tissue. When uncoiled, the tube is about the diameter of a quill, and varies in length from 10 to 15 cm.; it ends posteriorly in a cul-de-sac; its anterior extremity becomes constricted into a narrow straight duct called the excretory duct of seminal gland (or duct of the seminal vesicle), which joins with the corresponding ductus deferens to form the ejaculatory duct[WP]." [Wikipedia:Excretory_duct_of_seminal_gland]
synonym: "ductus excretorius (vesicula seminalis)" EXACT [FMA:19473]
synonym: "ductus excretorius glandulae vesiculosae" EXACT OMO:0003011 [FMA:19473, FMA:TA]
synonym: "ductus excretorius glandulae vesiculosae" RELATED OMO:0003011 [Wikipedia:Excretory_duct_of_seminal_gland]
synonym: "excretory duct of seminal gland" EXACT [FMA:19473]
synonym: "seminal vesicle duct" EXACT [FMA:19473]
xref: EMAPA:29282
xref: FMA:19473
xref: SCTID:279675008
xref: Wikipedia:Excretory_duct_of_seminal_gland
is_a: UBERON:0000025 ! tube
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005904 ! duct of male reproductive system
intersection_of: UBERON:0000058 ! duct
intersection_of: part_of UBERON:0000998 ! seminal vesicle
relationship: channel_for UBERON:0010143 ! seminal vesicle fluid
relationship: channels_into UBERON:0000999 ! ejaculatory duct
relationship: part_of UBERON:0000998 ! seminal vesicle
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray1160.png" xsd:anyURI

[Term]
id: UBERON:0005904
name: duct of male reproductive system
namespace: uberon
def: "Any of the ducts that are part of a male reproductive system." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
is_a: UBERON:0000058 ! duct
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000058 ! duct
intersection_of: part_of UBERON:0000079 ! male reproductive system
relationship: part_of UBERON:0000079 ! male reproductive system
property_value: curator_notes "this class groups the individual ducts in a variety of species" xsd:string

[Term]
id: UBERON:0005906
name: serous sac
namespace: uberon
def: "Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA]." [FMA:9689, https://github.com/obophenotype/uberon/issues/86]
comment: See notes for serous membrane
xref: FMA:9689
xref: SCTID:362890006
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000062 ! organ
relationship: has_part UBERON:0000042 ! serous membrane
relationship: has_part UBERON:0002553 ! anatomical cavity
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall

[Term]
id: UBERON:0005911
name: endo-epithelium
namespace: uberon
def: "Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA]." [FMA:69065]
synonym: "endoderm-derived epithelium" EXACT []
synonym: "endoepithelium" EXACT []
xref: FMA:69065
is_a: UBERON:0000483 ! epithelium
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000483 ! epithelium
intersection_of: develops_from UBERON:0000925 ! endoderm

[Term]
id: UBERON:0005913
name: zone of bone organ
namespace: uberon
synonym: "bone organ zone" EXACT [FMA:10483]
xref: FMA:10483
is_a: UBERON:0034944 {source="FMA"} ! zone of organ
relationship: composed_primarily_of UBERON:0002481 ! bone tissue
relationship: part_of UBERON:0001474 ! bone element

[Term]
id: UBERON:0005944
name: axial skeleton plus cranial skeleton
namespace: uberon
def: "Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]." [FMA:71221, https://github.com/obophenotype/uberon/issues/44, https://github.com/obophenotype/uberon/wiki/The-axial-skeleton, VSAO:0000056, Wikipedia:Axial_skeleton]
subset: human_reference_atlas
subset: pheno_slim
subset: uberon_slim
synonym: "skeleton axiale" RELATED OMO:0003011 [Wikipedia:Axial_skeleton]
xref: AAO:0000963
xref: EMAPA:17214
xref: EMAPA:18043
xref: MA:0000308
xref: NCIT:C32172
xref: SCTID:361725000
xref: UMLS:C0222645 {source="ncithesaurus:Axial_Skeleton"}
xref: VSAO:0000056
xref: Wikipedia:Axial_skeleton
xref: XAO:0004011
is_a: UBERON:0010912 ! subdivision of skeleton
relationship: connected_to UBERON:0002091 {gci_relation="part_of", gci_filler="NCBITaxon:7776"} ! appendicular skeleton
relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system
relationship: develops_from UBERON:0003089 ! sclerotome
relationship: part_of UBERON:0011137 ! axial skeletal system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/8b/Axial_skeleton_diagram.svg" xsd:anyURI
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: RO:0002175 NCBITaxon:9606
property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton" xsd:anyURI
property_value: UBPROP:0000001 "Skeletal subdivision of the central body axis including the cranium, vertebrae, notochord, ribs, and sternum.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000056", ontology="VSAO", source="PSPUB:0000170"}

[Term]
id: UBERON:0005945
name: neurocranial trabecula
namespace: uberon
subset: efo_slim
synonym: "neurocranial trabeculae" EXACT OMO:0003004 [ZFA:0001321]
synonym: "trabecula" BROAD SENSU [ZFA:0001321]
synonym: "trabecular cartilage" BROAD [ZFA:0001321]
xref: EFO:0003677
xref: TAO:0001321
xref: ZFA:0001321
is_a: UBERON:0000440 ! trabecula
is_a: UBERON:0003932 {source="ZFA"} ! cartilage element of chondrocranium
relationship: part_of UBERON:0003112 {source="ZFA"} ! olfactory region

[Term]
id: UBERON:0005946
name: outflow tract of atrium
namespace: uberon
def: "An outflow tract that is part of a cardiac atrium." [OBOL:automatic]
synonym: "outflow part of atrium" EXACT [FMA:14141]
xref: FMA:14141
is_a: UBERON:0004145 ! outflow tract
intersection_of: UBERON:0004145 ! outflow tract
intersection_of: part_of UBERON:0002081 ! cardiac atrium
relationship: continuous_with UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0002081 ! cardiac atrium

[Term]
id: UBERON:0005953
name: outflow part of right ventricle
namespace: uberon
def: "Anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk." [MP:0010428]
synonym: "arterial cone" RELATED [MP:0010428]
synonym: "conus arteriosus" RELATED [MP:0010428]
synonym: "conus arteriosus (infundibulum)" EXACT [FMA:7216]
synonym: "infundibulum" BROAD [Wikipedia:Conus_arteriosus]
synonym: "infundibulum of right ventricle" EXACT [FMA:7216, MP:0010428]
synonym: "outflow tract of right ventricle" EXACT [FMA:7216]
synonym: "pulmonary cone" RELATED [MP:0010428]
synonym: "pulmonary conus" EXACT [FMA:7216]
synonym: "pulmonary conus" RELATED [MP:0010428]
synonym: "right ventricle pulmonary outflow tract" EXACT [MP:0010428]
synonym: "right ventricular outflow tract" EXACT [MP:0010428]
synonym: "RVOT" EXACT OMO:0003000 [MP:0010428]
xref: EMAPA:37926 {source="MA:th"}
xref: FMA:7216
xref: NCIT:C61368
xref: SCTID:244379003
xref: UMLS:C1881209 {source="ncithesaurus:Infundibulum"}
is_a: UBERON:0005337 ! outflow tract of ventricle
intersection_of: UBERON:0005337 ! outflow tract of ventricle
intersection_of: part_of UBERON:0002080 ! heart right ventricle
relationship: continuous_with UBERON:0002333 ! pulmonary trunk
relationship: develops_from UBERON:0009889 {source="PMID:17276708"} ! secondary heart field
relationship: part_of UBERON:0002080 ! heart right ventricle

[Term]
id: UBERON:0005956
name: outflow part of left ventricle
namespace: uberon
def: "Anterosuperior fibrous portion of the left ventricle that connects to the ascending aorta." [MP:0010429]
subset: pheno_slim
synonym: "aortic vestibule" EXACT [FMA:9473, MP:0010429]
synonym: "heart left ventricle outflow tract" EXACT [MP:0010429]
synonym: "left ventricular outflow" EXACT [FMA:9473]
synonym: "left ventricular outflow tract" EXACT [HP:0011103]
synonym: "LVOT" EXACT OMO:0003000 [MP:0010429]
synonym: "outflow tract of left ventricle" EXACT [FMA:9473]
synonym: "Sibson vestibule" EXACT [MP:0010429]
synonym: "vestibulum aortae" EXACT OMO:0003011 [FMA:9473, FMA:TA]
xref: EMAPA:37925 {source="MA:th"}
xref: FMA:9473
xref: SCTID:264070001
xref: Wikipedia:Aortic_vestibule
is_a: UBERON:0005337 ! outflow tract of ventricle
intersection_of: UBERON:0005337 ! outflow tract of ventricle
intersection_of: part_of UBERON:0002084 ! heart left ventricle
relationship: part_of UBERON:0002084 ! heart left ventricle

[Term]
id: UBERON:0005965
name: outflow part of right atrium
namespace: uberon
def: "Outflow part of atrium which consists of wall and cavity of the outflow part of right atrium and the tricuspid valve.[FMA]." [FMA:9550, FMA:FMA]
synonym: "main part of right atrium" EXACT [FMA:9550]
synonym: "outflow tract of right atrium" EXACT [FMA:9550]
xref: FMA:9550
is_a: UBERON:0005946 ! outflow tract of atrium
intersection_of: UBERON:0005946 ! outflow tract of atrium
intersection_of: part_of UBERON:0002078 ! right cardiac atrium
relationship: part_of UBERON:0002078 ! right cardiac atrium

[Term]
id: UBERON:0005966
name: outflow part of left atrium
namespace: uberon
def: "An outflow tract of atrium that is part of a left atrium." [OBOL:automatic]
synonym: "main part of left atrium" EXACT [FMA:9551]
synonym: "outflow tract of left atrium" EXACT [FMA:9551]
xref: FMA:9551
is_a: UBERON:0005946 ! outflow tract of atrium
intersection_of: UBERON:0005946 ! outflow tract of atrium
intersection_of: part_of UBERON:0002079 ! left cardiac atrium
relationship: part_of UBERON:0002079 ! left cardiac atrium

[Term]
id: UBERON:0005971
name: amniotic fold
namespace: uberon
def: "A sheet of somatopleure that grows upward over the embryo and eventually meets in the midline enclosing the embryo, eventually giving rise to the amnion and chorion[Kardong]." [ISBN:0073040584]
subset: pheno_slim
synonym: "amnionic fold" EXACT [http://placentation.ucsd.edu/glossfs.html]
xref: EMAPA:16076
is_a: UBERON:0000478 ! extraembryonic structure
relationship: develops_from UBERON:0004874 {source="ISBN:0073040584"} ! somatopleure
relationship: only_in_taxon NCBITaxon:32524 ! Amniota

[Term]
id: UBERON:0005979
name: crista terminalis
namespace: uberon
def: "The vertical crest of the interior wall of the right atrium that lies to the right of the sinus of the vena cava and separates this from the remainder of the right atrium." [MP:0010495]
subset: pheno_slim
synonym: "crista terminalis atrii dextri" EXACT OMO:0003011 [FMA:9236, FMA:TA]
synonym: "crista terminalis cordis" EXACT [FMA:9236]
synonym: "crista terminalis of right atrium" EXACT [FMA:9236]
xref: EMAPA:37837 {source="MA:th"}
xref: FMA:9236
xref: SCTID:277693004
xref: Wikipedia:Crista_terminalis
is_a: UBERON:0000064 ! organ part
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: contributes_to_morphology_of UBERON:0002078 ! right cardiac atrium
relationship: part_of UBERON:0002078 ! right cardiac atrium

[Term]
id: UBERON:0005983
name: heart layer
namespace: uberon
def: "The laminar structure of the heart." [MP:0010545]
subset: non_informative
subset: pheno_slim
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: part_of UBERON:0000948 ! heart
relationship: contributes_to_morphology_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart

[Term]
id: UBERON:0005985
name: coronary vessel
namespace: uberon
def: "Any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation." [MP:0010551]
subset: pheno_slim
xref: MESH:D003331
xref: Wikipedia:Coronary_circulation
is_a: UBERON:0000055 ! vessel
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000055 ! vessel
intersection_of: part_of UBERON:0000948 ! heart
relationship: contributes_to_morphology_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart
property_value: editor_note "TODO - change relation from part_of" xsd:string

[Term]
id: UBERON:0005988
name: atrium myocardial trabecula
namespace: uberon
def: "The supporting bundles of muscular fibers lining the walls of the atrial myocardium." [MP:0010581, ZFA:0005810]
subset: pheno_slim
synonym: "atrial trabecula" EXACT []
synonym: "atrium myocardial trabeculae" EXACT OMO:0003004 [MP:0010581]
synonym: "trabecula of atrium" EXACT []
synonym: "trabecular layer of atrium" EXACT []
synonym: "trabecular layer of the atrium" EXACT [ZFA:0005810]
xref: EMAPA:37432 {source="MA:th"}
xref: ZFA:0005810
is_a: UBERON:0000440 ! trabecula
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000440 ! trabecula
intersection_of: part_of UBERON:0002302 ! myocardium of atrium
relationship: contributes_to_morphology_of UBERON:0002302 ! myocardium of atrium
relationship: part_of UBERON:0002302 ! myocardium of atrium
relationship: part_of UBERON:0004124 {source="ZFA"} ! myocardium trabecular layer

[Term]
id: UBERON:0005989
name: atrioventricular septum
namespace: uberon
def: "The wall of the heart that separates the right atrium and left ventricle; and is located just above the septal cusp of the tricuspid valve." [MP:0010592]
subset: pheno_slim
synonym: "membranous atrioventricular septum" EXACT [FMA:7136]
xref: EMAPA:37431 {source="MA:th"}
xref: FMA:7136
xref: SCTID:280151006
xref: Wikipedia:Atrioventricular_septum
is_a: UBERON:0002099 ! cardiac septum
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0002099 ! cardiac septum
intersection_of: adjacent_to UBERON:0002078 ! right cardiac atrium
intersection_of: adjacent_to UBERON:0002084 ! heart left ventricle
relationship: adjacent_to UBERON:0002078 ! right cardiac atrium
relationship: adjacent_to UBERON:0002084 ! heart left ventricle
relationship: develops_from UBERON:0002062 {source="PMID:15797462", source="Wikipedia"} ! endocardial cushion

[Term]
id: UBERON:0006002
name: vitelline artery
namespace: uberon
def: "The paired arteries that carry blood to the yolk sac from the dorsal aorta." [MP:0010664, Wikipedia:Vitelline_arteries]
comment: Development notes:; the vitelline arteries give rise to the celiac artery, superior mesenteric artery, and inferior mesenteric artery in the adult[MP:0010664]
subset: pheno_slim
xref: EHDAA2:0002208
xref: EMAPA:16207
xref: Wikipedia:Vitelline_arteries
is_a: UBERON:0001637 ! artery
is_a: UBERON:0004365 ! vitelline blood vessel
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001040 ! yolk sac
relationship: connecting_branch_of UBERON:0005805 {notes="ventral branch"} ! dorsal aorta
relationship: supplies UBERON:0001040 ! yolk sac
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/55/Gray31.png" xsd:anyURI

[Term]
id: UBERON:0006003
name: integumentary adnexa
namespace: uberon
def: "Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers." [http://code.google.com/p/caro2/issues/detail?id=5, http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "adnexae cutis" RELATED OMO:0003011 [Wikipedia:Skin_appendage]
synonym: "body hair or bristle" NARROW [GO:GO]
synonym: "skin adnexa" RELATED [Wikipedia:Skin_appendage]
synonym: "skin adnexal structure" RELATED []
synonym: "skin appendage" RELATED [Wikipedia:Skin_appendage]
xref: EMAPA:37883 {source="MA:th"}
xref: Wikipedia:Skin_appendage
is_a: UBERON:0000064 ! organ part
relationship: part_of UBERON:0002416 ! integumental system
property_value: editor_note "add subclasses based on resolution of CARO tracker item. Also check: adnexal gland. Note that MP implicitly includes hypodermis." xsd:string
property_value: UBPROP:0000001 "the tissue or structures associated with or embedded in the skin such as hair and hair follicles, sweat glands, sebaceous glands and claws or nails[MP:0010678]" xsd:string {source="MP:0010678"}

[Term]
id: UBERON:0006056
name: posterior surface of head
namespace: uberon
is_a: UBERON:0036215 ! anatomical surface region
intersection_of: UBERON:0036215 ! anatomical surface region
intersection_of: in_posterior_side_of UBERON:0000033 ! head
relationship: in_posterior_side_of UBERON:0000033 ! head
relationship: part_of UBERON:0000033 ! head

[Term]
id: UBERON:0006068
name: bone of tail
namespace: uberon
def: "A bone that is part of a post-anal tail." [OBOL:automatic]
subset: pheno_slim
synonym: "tail bone" RELATED [MA:0000696]
synonym: "tail vertebra" RELATED [http://orcid.org/0000-0002-6601-2165]
xref: EMAPA:18042
xref: MA:0000696
is_a: UBERON:0001474 ! bone element
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0007812 ! post-anal tail
relationship: part_of UBERON:0007812 ! post-anal tail
property_value: UBPROP:0000012 "MA has distinct classes for 'tail bone', 'caudal vertebra' and 'coccygeal vertebra' but these may all be equivalent. This class may be obsoleted in future." xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0006071
name: caudal region
namespace: uberon
def: "Subdivision of an organism along anterior-posterior axis that is the posteriormost region, extending past the anus (or cloaca, if present), consisting of a tail in some fully formed chordates (or a tail bud in embryos). In animals that have a sacral region, this is the region immediately posterior to this." [http://orcid.org/0000-0002-6601-2165]
synonym: "post-anal caudal region" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "post-anal tail region" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "postsacral region" RELATED [AAO:0000082]
synonym: "tail region" RELATED [AAO:0000082]
xref: XAO:0000087
is_a: UBERON:0011676 ! subdivision of organism along main body axis
relationship: has_skeleton UBERON:0006076 ! caudal region of vertebral column
relationship: part_of UBERON:0000154 ! posterior region of body
relationship: posterior_to UBERON:0001245 ! anus
property_value: UBPROP:0000008 "This region is reduced in humans and corresponds to the coccyx" xsd:string
property_value: UBPROP:0000012 "We follow XAO is distinguishing the tail region from the tail; the tail bud is part of the tail region; the tail starts after the tail bud" xsd:string {external_ontology="XAO"}

[Term]
id: UBERON:0006072
name: cervical region of vertebral column
namespace: uberon
def: "That portion of the spine comprising the cervical vertebrae. The neck area of the spine." [http://medical-dictionary.thefreedictionary.com/]
subset: pheno_slim
synonym: "axial skeleton cervical region" EXACT [MA:0003154]
synonym: "cervical skeleton" EXACT [EHDAA2:0000238]
synonym: "cervical spinal column" EXACT [FMA:24138]
synonym: "cervical spine" EXACT [FMA:24138]
synonym: "cervical vertebrae series" EXACT []
synonym: "cervical vertebral column" EXACT [FMA:24138]
synonym: "skeletal system of neck" RELATED [FMA:24138]
xref: AAO:0000092
xref: BTO:0004148
xref: EHDAA2:0000238
xref: EHDAA:5051
xref: EMAPA:17215
xref: FMA:24138
xref: MA:0003154
xref: NCIT:C69313
xref: SCTID:260488005
xref: UMLS:C0728985 {source="ncithesaurus:Cervical_Spine"}
is_a: UBERON:0006077 ! subdivision of vertebral column
intersection_of: UBERON:0006077 ! subdivision of vertebral column
intersection_of: subdivision_of UBERON:0005434 ! cervical region
relationship: part_of UBERON:0002090 ! postcranial axial skeleton
relationship: part_of UBERON:0012477 {source="FMA"} ! dorsal part of neck
relationship: subdivision_of UBERON:0005434 ! cervical region
property_value: UBPROP:0000001 "Anterior region of the vertebral column consisting of one to 19 or 20 vertebrae.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000092", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"}

[Term]
id: UBERON:0006073
name: thoracic region of vertebral column
namespace: uberon
def: "That part of the spine comprising the thoracic vertebrae." [http://medical-dictionary.thefreedictionary.com/]
subset: pheno_slim
synonym: "axial skeleton thoracic region" EXACT [MA:0003155]
synonym: "columna vertebralis thoracicus" EXACT [FMA:9140]
synonym: "thoracic spine" EXACT [FMA:9140]
synonym: "thoracic vertebrae series" EXACT []
synonym: "thoracic vertebral column" EXACT [FMA:9140]
xref: AAO:0000612
xref: BTO:0004150
xref: EHDAA:5063
xref: EMAPA:17396
xref: FMA:9140
xref: MA:0003155
xref: NCIT:C69315
xref: SCTID:243931006
xref: UMLS:C0581269 {source="ncithesaurus:Thoracic_Spine"}
is_a: UBERON:0006077 ! subdivision of vertebral column
intersection_of: UBERON:0006077 ! subdivision of vertebral column
intersection_of: subdivision_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0008231 {source="FMA"} ! dorsal thoracic segment of trunk
relationship: part_of UBERON:0014477 ! thoracic skeleton
relationship: subdivision_of UBERON:0000915 ! thoracic segment of trunk
property_value: UBPROP:0000001 "Region of the vertebral column between the atlas and the sacrum consisting of seven to 285 vertebrae.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000612", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"}

[Term]
id: UBERON:0006076
name: caudal region of vertebral column
namespace: uberon
def: "Subdivision of vertebral column that corresponds to the caudal subdivision of the body, containing the caudal vertebrae." [UBERONREF:0000006]
synonym: "axial skeleton tail region" EXACT [MA:0003158]
synonym: "caudal region" RELATED [AAO:0000082]
synonym: "caudal skeleton" EXACT [UBERONREF:0000006]
synonym: "caudal vertebrae series" EXACT [http://purl.bioontology.org/ontology/provisional/a047a2d5-418f-4d9c-ad21-ee0b7c29c29d]
synonym: "postsacral region" RELATED [AAO:0000082]
synonym: "tail region" RELATED [AAO:0000082]
xref: AAO:0000082
xref: EMAPA:18043
xref: MA:0003158
is_a: UBERON:0006077 ! subdivision of vertebral column
intersection_of: UBERON:0006077 ! subdivision of vertebral column
intersection_of: subdivision_of UBERON:0006071 ! caudal region
relationship: part_of UBERON:0002090 ! postcranial axial skeleton
relationship: part_of UBERON:0006071 ! caudal region
relationship: subdivision_of UBERON:0006071 ! caudal region
property_value: UBPROP:0000001 "Region of the vertebral column posterior to the caudal-sacral region, that may consists of two or three to more than 100 vertebrae. These vertebrae exhibit a gradual reduction in the sizes of their transverse processes and zygapophyses, but these structures are never entirely absent. All caudal vertebrae bear haemal arches.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000082", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"}
property_value: UBPROP:0000012 "in AAO, this is posterior to the caudal-sacral region" xsd:string {external_ontology="AAO"}

[Term]
id: UBERON:0006077
name: subdivision of vertebral column
namespace: uberon
def: "A collection of all skeletal elements in some subdivision of the vertebral column." [https://orcid.org/0000-0002-6601-2165]
subset: non_informative
synonym: "subdivision of vertebral skeleton" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "vertebrae series" EXACT []
synonym: "vertebral column subdivision" EXACT [FMA:16201]
synonym: "vertebral region" RELATED []
synonym: "vertebral series" EXACT []
synonym: "vertebral subdivision" RELATED []
xref: FMA:16201
is_a: UBERON:0000075 ! subdivision of skeletal system
intersection_of: UBERON:0000075 ! subdivision of skeletal system
intersection_of: subdivision_of UBERON:0001130 ! vertebral column
relationship: part_of UBERON:0001130 ! vertebral column
relationship: part_of UBERON:0001137 {source="FMA"} ! dorsum
relationship: subdivision_of UBERON:0001130 ! vertebral column

[Term]
id: UBERON:0006170
name: mesonephric capsule
namespace: uberon
def: "The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [DOI:10.1371/journal.pone.0099864, GO:0061285, GOC:mtg_kidney_jan10]
is_a: UBERON:0002015 ! kidney capsule
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0002015 ! kidney capsule
intersection_of: part_of UBERON:0000080 ! mesonephros
relationship: part_of UBERON:0000080 ! mesonephros

[Term]
id: UBERON:0006207
name: aortico-pulmonary spiral septum
namespace: uberon
alt_id: UBERON:0005999
def: "The spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during development. The actual mechanism of septation of the outflow tract is poorly understood, but is recognized as a dynamic process with contributions from contractile, hemodynamic, and extracellular matrix interactions." [MP:0010650, Wikipedia:Aorticopulmonary_septum]
subset: emapa_ehdaa2
subset: pheno_slim
synonym: "aortic septum" RELATED [Wikipedia:Aorticopulmonary_septum]
synonym: "aortico-pulmonary septum" EXACT [Wikipedia:Aorticopulmonary_septum]
synonym: "aorticopulmonary septum" EXACT [Wikipedia:Aorticopulmonary_septum]
synonym: "septum aorticopulmonale" EXACT OMO:0003011 [Wikipedia:Aorticopulmonary_septum]
synonym: "spiral septum" RELATED [Wikipedia:Aorticopulmonary_septum]
xref: CALOHA:TS-2409
xref: EHDAA2:0000136
xref: EHDAA:2592
xref: EMAPA:16827
xref: VHOG:0000502
xref: Wikipedia:Aorticopulmonary_septum
is_a: UBERON:0004142 ! outflow tract septum
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0002099 ! cardiac septum
intersection_of: adjacent_to UBERON:0002333 ! pulmonary trunk
intersection_of: adjacent_to UBERON:0005805 ! dorsal aorta
relationship: adjacent_to UBERON:0002333 ! pulmonary trunk
relationship: adjacent_to UBERON:0005805 ! dorsal aorta
relationship: develops_from UBERON:0000095 {source="PMID:6844926", source="Wikipedia"} ! cardiac neural crest
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b9/Gray470.png" xsd:anyURI

[Term]
id: UBERON:0006211
name: buccopharyngeal membrane
namespace: uberon
def: "The thin bilaminar membrane derived from the prechordal plate that is devoid of mesoderm and formed by the apposition of the stomodeal ectoderm with the foregut endoderm; after the embryonic head fold has evolved it lies at the caudal limit of the stomodeum, forming a septum between the primitive mouth and pharynx; the membrane eventually disappears, and thus a communication is established between the mouth and the future pharynx." [MP:0012521]
subset: emapa_ehdaa2
subset: pheno_slim
synonym: "oral membrane" RELATED [MP:0012521]
synonym: "oral plate" RELATED [MP:0012521]
synonym: "oropharyngeal membrane" RELATED [Wikipedia:Buccopharyngeal_membrane]
synonym: "pharyngeal membrane" RELATED INCONSISTENT [MP:0012521]
xref: EHDAA2:0000189
xref: EHDAA:536
xref: EMAPA:16259
xref: FMA:313607
xref: SCTID:361412007
xref: VHOG:0000380
xref: Wikipedia:Buccopharyngeal_membrane
is_a: UBERON:0003037 ! septum
relationship: has_developmental_contribution_from UBERON:0000924 ! ectoderm
relationship: has_developmental_contribution_from UBERON:0000925 ! endoderm
relationship: overlaps UBERON:0000930 ! stomodeum
relationship: overlaps UBERON:0001042 ! chordate pharynx
relationship: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0006264 {source="EHDAA2"} ! mouth-foregut junction
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/93/Gray977.png" xsd:anyURI

[Term]
id: UBERON:0006217
name: cloacal membrane
namespace: uberon
def: "The membrane that covers the embryonic cloaca, formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm; the urorectal septum joins the cloacal membrane and divides it into an anal membrane and a urogenital membrane; the point where the urorectal septum intersects the cloacal membrane is the future site of the perineal body; proliferation of mesoderm and ectoderm around the cloacal membrane produces primordial tissues of the external genitalia in both sexes: the genital tubercle, genital folds, and genital swellings." [MP:0011837, MP:anna, Wikipedia:Cloacal_membrane]
subset: emapa_ehdaa2
subset: pheno_slim
synonym: "embryonic cloacal membrane" EXACT []
synonym: "membrana cloacalis" RELATED OMO:0003011 [Wikipedia:Cloacal_membrane]
xref: EHDAA2:0000257
xref: EHDAA:214
xref: EHDAA:2933
xref: EMAPA:16832
xref: FMA:295525
xref: NCIT:C34128
xref: SCTID:308826008
xref: UMLS:C0231056 {source="ncithesaurus:Cloacal_Membrane"}
xref: VHOG:0001198
xref: Wikipedia:Cloacal_membrane
is_a: UBERON:0000158 ! membranous layer
relationship: contributes_to_morphology_of UBERON:0000163 ! embryonic cloaca
relationship: develops_from UBERON:0004341 {source="Wikipedia"} ! primitive streak
relationship: has_developmental_contribution_from UBERON:0000924 ! ectoderm
relationship: has_developmental_contribution_from UBERON:0000925 ! endoderm
relationship: part_of UBERON:0000163 ! embryonic cloaca
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray991.png" xsd:anyURI
property_value: UBPROP:0000001 "A membrane that separates the proctodeum and the hindgut in the early embryo. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.497, see_Kardong_KV][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001198", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "In mammals, the cloaca exists as an embryonic structure that undergoes septation to become distinct urethral, anal, and genital orifices.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001198", ontology="VHOG", source="PMID:11830557 De Santa Barbara P, Roberts DJ, Tail gut endoderm and gut/genitourinary/tail development: a new tissue-specific role for Hoxa13. Development (2002)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0006218
name: common atrial chamber
namespace: uberon
subset: emapa_ehdaa2
xref: EHDAA:1267
xref: EMAPA:16342
xref: RETIRED_EHDAA2:0000268
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0002081 ! cardiac atrium

[Term]
id: UBERON:0006227
name: ethmoid bone primordium
namespace: uberon
subset: emapa_ehdaa2
xref: EHDAA2:0000456
xref: EHDAA:8363
xref: EMAPA:18023
xref: FMA:312597
is_a: UBERON:0001048 ! primordium
intersection_of: UBERON:0001048 ! primordium
intersection_of: has_potential_to_develop_into UBERON:0001679 ! ethmoid bone
relationship: develops_from UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest
relationship: has_potential_to_develop_into UBERON:0001679 ! ethmoid bone
relationship: part_of UBERON:0002517 {source="FMA"} ! basicranium
relationship: part_of UBERON:0011241 {source="AAO"} ! ethmoid region
property_value: editor_note "consider obsoleting, the ethmoid is endochondral?" xsd:string

[Term]
id: UBERON:0006233
name: female genital tubercle
namespace: uberon
def: "A differentiated genital tubercle that is part of a female reproductive system." [OBOL:automatic]
subset: emapa_ehdaa2
synonym: "genital tubercle of female" EXACT [EMAPA:18680]
xref: EHDAA:8118
xref: EMAPA:18680
xref: RETIRED_EHDAA2:0000500
xref: VHOG:0000666
is_a: UBERON:0011757 ! differentiated genital tubercle
intersection_of: UBERON:0011757 ! differentiated genital tubercle
intersection_of: part_of UBERON:0000474 ! female reproductive system
relationship: part_of UBERON:0005056 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! external female genitalia

[Term]
id: UBERON:0006235
name: foregut-midgut junction
namespace: uberon
def: "An anatomical junctions that overlaps the foregut and midgut." [OBOL:automatic]
subset: emapa_ehdaa2
xref: EHDAA2:0000569
xref: EHDAA:526
xref: EMAPA:16363
xref: VHOG:0000291
is_a: UBERON:1100000 ! digestive tract junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0001041 ! foregut
intersection_of: connects UBERON:0001045 ! midgut
relationship: connects UBERON:0001041 ! foregut
relationship: connects UBERON:0001045 ! midgut
relationship: part_of UBERON:0001555 ! digestive tract
property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000291", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0006236
name: tetrapod frontal bone primordium
namespace: uberon
subset: emapa_ehdaa2
synonym: "frontal bone primordium" EXACT [EHDAA2:0000577]
xref: EHDAA2:0000577
xref: EHDAA:9540
xref: EMAPA:18017
xref: FMA:312589
is_a: UBERON:0001048 ! primordium
intersection_of: UBERON:0001048 ! primordium
intersection_of: has_potential_to_develop_into UBERON:0000209 ! tetrapod frontal bone
relationship: has_potential_to_develop_into UBERON:0000209 ! tetrapod frontal bone

[Term]
id: UBERON:0006238
name: future brain
namespace: uberon
def: "The embryonic precursor of the brain." [NLX:94995]
subset: cumbo
subset: efo_slim
subset: emapa_ehdaa2
subset: vertebrate_core
synonym: "brain rudiment" EXACT [TAO:0000146]
synonym: "embryonic brain" RELATED [BTO:0004726]
synonym: "encephalon" NARROW [NLX:94995]
synonym: "presumptive brain" EXACT [ZFA:0000146]
xref: BAMS:Enc
xref: BTO:0004726
xref: EFO:0003431
xref: EHDAA:300
xref: EHDAA:830
xref: EMAPA:16089
xref: FMA:312967
xref: RETIRED_EHDAA2:0000591
xref: TAO:0000146
xref: ZFA:0000146
is_a: UBERON:0006598 ! presumptive structure
relationship: has_potential_to_develop_into UBERON:0000955 ! brain
relationship: part_of UBERON:0002346 ! neurectoderm
property_value: UBPROP:0000001 "The embryonic precursor of the brain and the set of mature brain structures that derive from it (CUMBO)" xsd:string {source="http://neurolex.org/wiki/Cumbo_terms"}

[Term]
id: UBERON:0006239
name: future central tendon
namespace: uberon
def: "A tendon that has the potential to develop into a central tendon." [OBOL:automatic]
subset: emapa_ehdaa2
synonym: "cranial derivative of septum transversum" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "cranial part of septum transversum" RELATED [http://orcid.org/0000-0002-6601-2165]
xref: EHDAA2:0000593
xref: EHDAA:4118
xref: EMAPA:25035
is_a: UBERON:0000043 ! tendon
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0000043 ! tendon
intersection_of: has_potential_to_develop_into UBERON:0006670 ! central tendon of diaphragm
relationship: develops_from UBERON:0004161 {notes="mesenchyme", region="cranial part", source="Wikipedia"} ! septum transversum
relationship: has_potential_to_develop_into UBERON:0006670 ! central tendon of diaphragm
relationship: part_of UBERON:0010084 {source="EHDAA2"} ! future diaphragm
property_value: UBPROP:0000011 "The cranial part of the septum transversum gives rise to the central tendon of the diaphragm and is the origin of the myoblasts that invade the pleuroperitoneal folds resulting in the formation of the muscular diaphragm." xsd:string

[Term]
id: UBERON:0006241
name: future spinal cord
namespace: uberon
subset: efo_slim
subset: vertebrate_core
synonym: "presumptive spinal cord" EXACT [ZFA:0000417]
synonym: "presumptive spinal cord neural keel" EXACT [TAO:0000417]
synonym: "presumptive spinal cord neural plate" EXACT [TAO:0000417]
synonym: "presumptive spinal cord neural rod" EXACT [TAO:0000417]
xref: EFO:0003438
xref: EHDAA2:0000674
xref: EHDAA:898
xref: EMAPA:16092
xref: EMAPA:16755
xref: TAO:0000417
xref: ZFA:0000417
is_a: UBERON:0006598 ! presumptive structure
relationship: has_potential_to_develop_into UBERON:0001049 {source="EHDAA2"} ! neural tube
relationship: has_potential_to_develop_into UBERON:0002240 ! spinal cord
relationship: part_of UBERON:0001017 ! central nervous system

[Term]
id: UBERON:0006242
name: gallbladder primordium
namespace: uberon
def: "A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops." [ISBN:0815318960, XAO:0004205]
subset: emapa_ehdaa2
synonym: "gall bladder primordium" EXACT []
xref: EHDAA2:0000700
xref: EHDAA:3047
xref: EMAPA:16713
xref: XAO:0004205
is_a: UBERON:0001048 ! primordium
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0001048 ! primordium
intersection_of: has_potential_to_develop_into UBERON:0002110 ! gallbladder
relationship: develops_from UBERON:0001152 {source="EHDAA2"} ! cystic duct
relationship: has_potential_to_develop_into UBERON:0002110 ! gallbladder
relationship: part_of UBERON:0004912 {source="EMAPA"} ! biliary bud

[Term]
id: UBERON:0006261
name: male genital tubercle
namespace: uberon
def: "A differentiated genital tubercle that is part of a male reproductive system." [OBOL:automatic]
subset: emapa_ehdaa2
synonym: "genital tubercle of male" EXACT [EMAPA:17969]
synonym: "penis anlage" RELATED [EMAPA:17969]
xref: EHDAA:8138
xref: EMAPA:17969
xref: RETIRED_EHDAA2:0001048
xref: VHOG:0000667
is_a: UBERON:0011757 ! differentiated genital tubercle
intersection_of: UBERON:0011757 ! differentiated genital tubercle
intersection_of: part_of UBERON:0000079 ! male reproductive system
relationship: part_of UBERON:0004053 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! external male genitalia

[Term]
id: UBERON:0006264
name: mouth-foregut junction
namespace: uberon
def: "An anatomical junctions that overlaps the mouth and foregut." [OBOL:automatic]
subset: emapa_ehdaa2
xref: EHDAA:534
xref: EMAPA:16258
xref: RETIRED_EHDAA2:0001205
xref: VHOG:0000592
is_a: UBERON:0007651 ! anatomical junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: overlaps UBERON:0000165 ! mouth
intersection_of: overlaps UBERON:0001041 ! foregut
relationship: overlaps UBERON:0000165 ! mouth
relationship: overlaps UBERON:0001041 ! foregut
relationship: part_of UBERON:0001555 ! digestive tract

[Term]
id: UBERON:0006267
name: notochordal plate
namespace: uberon
def: "The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord." [VHOG:0001212]
subset: emapa_ehdaa2
xref: EHDAA2:0001278
xref: EHDAA:264
xref: EMAPA:16101
xref: NCIT:C34231
xref: UMLS:C1518429 {source="ncithesaurus:Notochordal_Plate"}
xref: VHOG:0001212
is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
relationship: develops_from UBERON:0006268 {source="EHDAA2"} ! notochordal process
property_value: editor_note "TODO - check ordering; awaiting confirmation from JB" xsd:string
property_value: UBPROP:0000001 "The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001212", ontology="VHOG", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0006268
name: notochordal process
namespace: uberon
def: "A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot." [http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/05embryonicperiod.htm]
comment: The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus.
subset: emapa_ehdaa2
synonym: "chordamesoderm" RELATED []
synonym: "presumptive notochord" RELATED []
xref: EHDAA2:0001279
xref: EHDAA:224
xref: EMAPA:16102
xref: FMA:293135
xref: NCIT:C34232
xref: UMLS:C1518430 {source="ncithesaurus:Notochordal_Process"}
xref: VHOG:0001213
is_a: UBERON:0005423 ! developing anatomical structure
relationship: develops_from UBERON:0000924 {source="EHDAA2"} ! ectoderm
relationship: only_in_taxon NCBITaxon:7711 ! Chordata

[Term]
id: UBERON:0006271
name: orbital fissure
namespace: uberon
def: "Either of two openings transmitting nerves and blood vessels to or from the orbit." [http://www.merriam-webster.com/medical/orbital%20fissure]
subset: emapa_ehdaa2
xref: EHDAA2:0001328
xref: EHDAA:10648
xref: EMAPA:18717
xref: SCTID:280546005
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0013685 ! foramen of skull
intersection_of: UBERON:0013685 ! foramen of skull
intersection_of: part_of UBERON:0001697 ! orbit of skull
relationship: part_of UBERON:0001697 ! orbit of skull

[Term]
id: UBERON:0006279
name: pleuroperitoneal canal
namespace: uberon
def: "Each of the canals that links the peritoneal cavity and the caudal part of a pleural cavity." [ISBN:0124020607, VHOG:0001505]
subset: emapa_ehdaa2
synonym: "pleuroperitoneal channel" RELATED [VHOG:0001505]
xref: EHDAA2:0001481
xref: EHDAA:4128
xref: EMAPA:17704
xref: EMAPA:17707
xref: SCTID:361413002
xref: VHOG:0001505
is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube
is_a: UBERON:0005291 ! embryonic tissue
intersection_of: UBERON:0003914 ! epithelial tube
intersection_of: connects UBERON:0001179 ! peritoneal cavity
intersection_of: connects UBERON:0002402 ! pleural cavity
relationship: connects UBERON:0001179 ! peritoneal cavity
relationship: connects UBERON:0002402 ! pleural cavity
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
relationship: part_of UBERON:0011997 {source="EHDAA2"} ! coelom
property_value: UBPROP:0000001 "Each of the canal that links the peritoneal cavity and the caudal part of a pleural cavity. [ISBN:0124020607][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001505", ontology="VHOG", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0006283
name: future cardiac ventricle
namespace: uberon
alt_id: UBERON:0010226
def: "Multi-tissue structure that is part of the heart tube and will become the cardiac ventricle." [ZFA:0001719]
comment: The embryonic ventricle or primitive ventricle of the developing heart gives rise to the trabeculated parts of the left and right ventricles. In contrast, the smooth parts of the left and right ventricles originate from the embryological bulbus cordis. The primitive ventricle becomes divided by a septum, the septum inferius or ventricular septum, which grows upward from the lower part of the ventricle, its position being indicated on the surface of the heart by a furrow. Its dorsal part increases more rapidly than its ventral portion, and fuses with the dorsal part of the septum intermedium. For a time an interventricular foramen exists above its ventral portion, but this foramen is ultimately closed by the fusion of the aortic septum with the ventricular septum[WP]
synonym: "early heart ventricle" EXACT []
synonym: "embryonic heart ventricle" EXACT []
synonym: "embryonic ventricle" BROAD []
synonym: "future heart ventricle" EXACT []
synonym: "presumptive cardiac ventricle heart tube" EXACT [ZFA:0001719]
synonym: "primitive ventricle" EXACT [EHDAA2:0001531]
synonym: "primitive ventricle of heart" EXACT [EMAPA:16350]
synonym: "primordial cardiac ventricle" EXACT [FMA:71006]
synonym: "primordial ventricle" EXACT [FMA:71006]
xref: EHDAA2:0001531
xref: EMAPA:16350
xref: FMA:71006
xref: NCIT:C34160
xref: SCTID:361524003
xref: TAO:0002231
xref: Wikipedia:Embryonic_ventricle
xref: ZFA:0001719
is_a: UBERON:0006598 ! presumptive structure
relationship: has_potential_to_develop_into UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0004141 {source="ZFA"} ! heart tube
relationship: part_of UBERON:0005498 {source="EMAPA"} ! primitive heart tube

[Term]
id: UBERON:0006293
name: spleen primordium
namespace: uberon
alt_id: UBERON:0009750
def: "A dense syncitial-like mesenchymal thickening in the dorsal mesogastrium[ISBN]. the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing spleen[MP]." [ISBN:0123747295, MP:0011263]
subset: pheno_slim
synonym: "left spleen primordium" NARROW [XAO:0000326]
synonym: "spleen mesenchyme" EXACT [MP:0011263]
synonym: "splenic mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "splenic primordium" EXACT [EHDAA2:0001904]
xref: EHDAA2:0001904
xref: EHDAA:3003
xref: EMAPA:18535
xref: XAO:0000326
is_a: UBERON:0001048 {source="XAO"} ! primordium
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
relationship: develops_from UBERON:0004872 {source="XAO"} ! splanchnic layer of lateral plate mesoderm
relationship: part_of UBERON:0005602 {source="EHDAA2-modified"} ! dorsal mesogastrium
property_value: UBPROP:0000012 "check difference between splenic and spleen in EMAPA; note that in EHDAA2 the class 'spleen' refers to the mesenchyme" xsd:string {external_ontology="EMAPA"}

[Term]
id: UBERON:0006304
name: future trigeminal ganglion
namespace: uberon
comment: See: https://github.com/obophenotype/mouse-anatomy-ontology/issues/13 and https://github.com/obophenotype/uberon/issues/693 -- consider merging into trigeminal ganglion, as this complicates the model
subset: emapa_ehdaa2
synonym: "trigeminal preganglion" RELATED [EMAPA:16663]
synonym: "trigeminal V preganglion" EXACT [EMAPA:16663]
xref: EHDAA:924
xref: EMAPA:16663
xref: RETIRED_EHDAA2:0002089
is_a: UBERON:0003869 ! presumptive ganglion
relationship: develops_from UBERON:0003070 ! trigeminal placode complex
relationship: develops_from UBERON:0005563 ! trigeminal neural crest
relationship: has_potential_to_develop_into UBERON:0001675 ! trigeminal ganglion
relationship: transformation_of UBERON:0003070 {source="EHDAA2"} ! trigeminal placode complex

[Term]
id: UBERON:0006311
name: chamber of eyeball
namespace: uberon
def: "A segment of the eyeball that is filled with refractive media." [http://orcid.org/0000-0002-6601-2165]
synonym: "chamber of eye" RELATED [BTO:0002085]
synonym: "eye chamber" EXACT [MA:0002459]
synonym: "eyeball chamber" EXACT [FMA:58071]
xref: BTO:0002085
xref: EMAPA:37529 {source="MA:th"}
xref: FMA:58071
xref: MA:0002459
xref: NCIT:C32301
xref: SCTID:280540004
xref: UMLS:C0459556 {source="ncithesaurus:Chamber_of_the_Eye"}
is_a: UBERON:0000063 ! organ subunit
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000063 ! organ subunit
intersection_of: location_of UBERON:0006312 ! ocular refractive media
intersection_of: part_of UBERON:0000019 ! camera-type eye
relationship: location_of UBERON:0006312 ! ocular refractive media
relationship: part_of UBERON:0000019 ! camera-type eye

[Term]
id: UBERON:0006312
name: ocular refractive media
namespace: uberon
def: "Body substance in a liquid or semi-solid state in the eyeball which serves to refract light." [http://orcid.org/0000-0002-6601-2165]
xref: MA:0001911
is_a: UBERON:0000463 ! organism substance
relationship: part_of UBERON:0000019 ! camera-type eye
property_value: UBPROP:0000009 "ocular refraction" xsd:string

[Term]
id: UBERON:0006314
name: bodily fluid
namespace: uberon
def: "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not." [MESH:A12.207, Wikipedia:Body_fluid]
subset: pheno_slim
synonym: "body fluid" EXACT [GAID:266]
synonym: "fluid" BROAD []
xref: BIRNLEX:20
xref: EMAPA:37441 {source="MA:th"}
xref: FMA:280556
xref: GAID:266
xref: galen:BodyFluid
xref: MESH:D001826
xref: Wikipedia:Body_fluid
is_a: UBERON:0000463 ! organism substance
intersection_of: UBERON:0000463 ! organism substance
intersection_of: has_quality PATO:0001548 ! quality of a liquid
relationship: has_quality PATO:0001548 ! quality of a liquid

[Term]
id: UBERON:0006331
name: brainstem nucleus
namespace: uberon
def: "A nucleus of brain that is part of a brainstem." [OBOL:automatic]
synonym: "brain stem nucleus" RELATED [EMAPA:32790]
xref: EMAPA:32790
xref: MA:0000821
is_a: UBERON:0002308 ! nucleus of brain
intersection_of: UBERON:0002308 ! nucleus of brain
intersection_of: part_of UBERON:0002298 ! brainstem
relationship: part_of UBERON:0002298 ! brainstem

[Term]
id: UBERON:0006347
name: communicating artery
namespace: uberon
def: "An artery that connects two larger arteries." [ncithesaurus:Communicating_Artery]
comment: Grouping for anterior and posterior
xref: EMAPA:18598
xref: MA:0001938
xref: NCIT:C52851
xref: UMLS:C1707451 {source="ncithesaurus:Communicating_Artery"}
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: connects UBERON:0001637 {cardinality="2"} ! artery
relationship: connects UBERON:0001637 ! artery

[Term]
id: UBERON:0006355
name: superior vesical vein
namespace: uberon
subset: human_reference_atlas
xref: EMAPA:18646
xref: MA:0002227
is_a: UBERON:0002460 {is_inferred="true", source="MA"} ! vesical vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0000056 ! ureter
relationship: drains UBERON:0000056 ! ureter
property_value: editor_note "inferred from artery" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0006435
name: os penis
namespace: uberon
def: "The unique bone located in the glans penis of most mammals except humans; it is used for copulation and varies in size and shape by species." [MGI:anna, MP:0009103]
subset: pheno_slim
synonym: "baculum" EXACT [Wikipedia:Baculum]
synonym: "os baculum" EXACT []
synonym: "penile bone" EXACT [MP:0009104, Wikipedia:Baculum]
synonym: "penis bone" EXACT [Wikipedia:Baculum]
xref: EMAPA:29769
xref: MA:0000406
xref: SCTID:27962002
xref: Wikipedia:Baculum
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0007719 ! bone of reproductive organ
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0000989 ! penis
relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia
relationship: part_of UBERON:0000989 ! penis
property_value: RO:0002161 NCBITaxon:9606
property_value: UBPROP:0000008 "found in most mammals, with the exception of humans" xsd:string

[Term]
id: UBERON:0006440
name: os clitoris
namespace: uberon
def: "The ossified region of endochondral and membranous bone located in the clitoris of most mammals except humans; it is homologous to the penile bone (aka as baculum, penis bone or os penis) in male mammals." [MP:0011849]
subset: pheno_slim
synonym: "baubellum" EXACT [Wikipedia:Baculum]
synonym: "clitoral bone" EXACT [MP:0011849]
synonym: "clitoris bone" EXACT []
synonym: "os clitoridis" EXACT [Wikipedia:Baculum]
xref: EMAPA:30823
xref: MA:0000387
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0007719 ! bone of reproductive organ
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0002411 ! clitoris
relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system
relationship: contributes_to_morphology_of UBERON:0002411 ! clitoris
relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia
relationship: part_of UBERON:0002411 ! clitoris
relationship: sexually_homologous_to UBERON:0006435 ! os penis
property_value: RO:0002161 NCBITaxon:9606

[Term]
id: UBERON:0006518
name: right lung lobe
namespace: uberon
def: "A lobe of lung that is part of a right lung." [OBOL:automatic]
synonym: "lobe of right lung" EXACT []
synonym: "lobe of the right lung" EXACT [ncithesaurus:Lobe_of_the_Right_Lung]
xref: EMAPA:35155
xref: MA:0001791
xref: NCIT:C48944
xref: SCTID:272654004
xref: UMLS:C1285106 {source="ncithesaurus:Lobe_of_the_Right_Lung"}
is_a: UBERON:0000101 ! lobe of lung
intersection_of: UBERON:0000101 ! lobe of lung
intersection_of: part_of UBERON:0002167 ! right lung
relationship: part_of UBERON:0002167 ! right lung
property_value: UBPROP:0000008 "4 in mice, divided into 3 in human by two interlobal fissures" xsd:string {source="ISBN:0123813611"}

[Term]
id: UBERON:0006530
name: seminal fluid
namespace: uberon
def: "A substance formed from the secretion of one or more glands of the male genital tract in which sperm cells are suspended." [http://orcid.org/0000-0002-6601-2165]
synonym: "male genital fluid" RELATED []
synonym: "male genital secretion" RELATED []
synonym: "milt" NARROW [PMID:31287811, PMID:35203131] {comment="CURATOR NOTE A secretion from the glands of the male reproductive system in some aquatic animals that contains sperm and is sprayed onto the eggs."}
synonym: "seminal fluid" RELATED [BTO:0001232]
synonym: "seminal plasma" EXACT [BTO:0001232]
xref: BTO:0001232
xref: CALOHA:TS-0918
xref: EMAPA:36543
xref: FMA:62967
xref: MA:0002523
xref: MAT:0000057
xref: MIAA:0000057
is_a: UBERON:0000456 ! secretion of exocrine gland
is_a: UBERON:0006536 ! male reproductive gland secretion
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: part_of UBERON:0001968 ! semen
intersection_of: produced_by UBERON:0005399 ! male reproductive gland
relationship: capable_of_part_of GO:0048240 ! sperm capacitation
relationship: capable_of_part_of GO:1902093 ! positive regulation of flagellated sperm motility
relationship: part_of UBERON:0001968 ! semen
property_value: curator_notes "this ontology contains a number of subtypes of seminal fluid, defined according to glands (which are more taxonomically restricted)" xsd:string
property_value: curator_notes "we follow FMA and make this class a generic superclass of the secretions of different glands (prostate, bulbo-urethreal, seminal vesicle). MA (and ncit) follows a mixture model, where these secretions are part of the seminal fluid" xsd:string
property_value: UBPROP:0000008 "This term covers a variety of species. Example: In D. melanogaster, seminal fluid proteins affect female receptivity, ovulation, oogenesis, sperm storage, sperm competition and mating plug formation" xsd:string {source="DOI:10.1046/j.1365-2540.2001.00961.x"}
property_value: UBPROP:0000009 "seminal fluid may have a role in sperm capacitation, sperm motility" xsd:string

[Term]
id: UBERON:0006535
name: skin secretion
namespace: uberon
def: "A portion of organism substance that secreted_by a zone of skin." [OBOL:automatic]
synonym: "skin fluid" RELATED []
synonym: "skin fluid/secretion" EXACT [MA:0002537]
synonym: "skin substance" RELATED []
xref: MA:0002537
is_a: UBERON:0000463 ! organism substance
intersection_of: UBERON:0000463 ! organism substance
intersection_of: produced_by UBERON:0000014 ! zone of skin
relationship: produced_by UBERON:0000014 ! zone of skin

[Term]
id: UBERON:0006536
name: male reproductive gland secretion
namespace: uberon
def: "A portion of organism substance that is secreted by a male reproductive gland." [UBERON:cjm]
synonym: "male reproductive system fluid" RELATED []
synonym: "male reproductive system fluid/secretion" EXACT [MA:0002521]
synonym: "male reproductive system secretion" RELATED []
xref: EMAPA:36541
xref: MA:0002521
is_a: UBERON:0022293 ! reproductive gland secretion
intersection_of: UBERON:0000463 ! organism substance
intersection_of: produced_by UBERON:0005399 ! male reproductive gland
relationship: produced_by UBERON:0005399 ! male reproductive gland

[Term]
id: UBERON:0006537
name: female reproductive gland secretion
namespace: uberon
def: "A portion of organism substance that is secreted by a female reproductive gland." [UBERON:cjm]
synonym: "female reproductive system fluid" RELATED []
synonym: "female reproductive system fluid/secretion" EXACT [MA:0002510]
synonym: "female reproductive system secretion" RELATED []
xref: MA:0002510
is_a: UBERON:0022293 ! reproductive gland secretion
intersection_of: UBERON:0000463 ! organism substance
intersection_of: produced_by UBERON:0005398 ! female reproductive gland
relationship: produced_by UBERON:0005398 ! female reproductive gland

[Term]
id: UBERON:0006538
name: respiratory system fluid/secretion
namespace: uberon
def: "A portion of organism substance that secreted_by a respiratory system." [OBOL:automatic]
synonym: "respiratory system fluid" RELATED []
synonym: "respiratory system secretion" RELATED []
xref: EMAPA:36550
xref: MA:0002533
xref: NCIT:C13722
xref: UMLS:C1514899 {source="ncithesaurus:Respiratory_System_Fluid_or_Secretion"}
is_a: UBERON:0000463 ! organism substance
intersection_of: UBERON:0000463 ! organism substance
intersection_of: produced_by UBERON:0001004 ! respiratory system
relationship: produced_by UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0006544
name: kidney vasculature
namespace: uberon
def: "A vasculature that is part of a kidney." [OBOL:automatic]
subset: human_reference_atlas
subset: vertebrate_core
xref: EMAPA:28457
xref: TAO:0005305
xref: ZFA:0005305
is_a: UBERON:0002201 ! vasculature of trunk
is_a: UBERON:0006876 ! vasculature of organ
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0002113 ! kidney
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0006553
name: renal duct
namespace: uberon
def: "A tube in the kidney that collect and transport urine." [ZFIN:ZDB-PUB-071029-9]
xref: TAO:0005289
xref: ZFA:0005289
is_a: UBERON:0000058 ! duct
intersection_of: UBERON:0000058 ! duct
intersection_of: part_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0002113 ! kidney
property_value: UBPROP:0000012 "in ZFA this is defined as part of mesonephros" xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0006555
name: excretory tube
namespace: uberon
def: "A tube that is part of a excretory system." [OBOL:automatic]
is_a: UBERON:0000025 ! tube
intersection_of: UBERON:0000025 ! tube
intersection_of: part_of UBERON:0001008 ! renal system
relationship: part_of UBERON:0001008 ! renal system

[Term]
id: UBERON:0006562
name: pharynx
namespace: uberon
def: "The pharynx is the part of the digestive system immediately posterior to the mouth[GO]." [GO:0060465]
subset: grouping_class
subset: uberon_slim
synonym: "anterior part of foregut" RELATED []
synonym: "pharyngeal tube" RELATED []
xref: MAT:0000049
xref: MESH:D010614
xref: MIAA:0000049
is_a: UBERON:0004921 ! subdivision of digestive tract
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
property_value: curator_notes "currently this is an extremely generic class, encompassing both protostomes and deuterostomes." xsd:string
property_value: IAO:0006012 "2023-04-20" xsd:string
property_value: UBPROP:0000007 "branchial" xsd:string
property_value: UBPROP:0000007 "pharyngeal" xsd:string

[Term]
id: UBERON:0006563
name: tunica media of pulmonary trunk
namespace: uberon
def: "Tunica media of artery which is continuous with the myocardium of right ventricle.[FMA]." [FMA:85030, FMA:FMA]
xref: FMA:85030
is_a: UBERON:0007239 ! tunica media of artery
intersection_of: UBERON:0002522 ! tunica media
intersection_of: part_of UBERON:0002333 ! pulmonary trunk
relationship: part_of UBERON:0002333 ! pulmonary trunk

[Term]
id: UBERON:0006565
name: female urethral meatus
namespace: uberon
def: "A urethral meatus that is part of a female urethra[Automatically generated definition]." [OBOL:automatic, Wikipedia:External_urethral_orifice_(female)]
synonym: "distal urethral opening of female" RELATED [EMAPA:36453]
synonym: "external orifice of female urethra" EXACT [FMA:85266]
synonym: "external urethral orifice (female)" EXACT [FMA:85266]
synonym: "female urethral meatus" EXACT [FMA:85266]
synonym: "ostium urethrae externum (urethra feminina)" EXACT OMO:0003011 [FMA:85266, FMA:TA]
synonym: "urethral meatus of clitoral urethra" EXACT [EMAPA:36453]
synonym: "urethral opening of clitoral urethra" RELATED [EMAPA:36453]
xref: EMAPA:36453
xref: FMA:85266
xref: MA:0002639
xref: SCTID:279479008
xref: Wikipedia:External_urethral_orifice_(female)
is_a: UBERON:0012240 ! urethral meatus
intersection_of: UBERON:0012240 ! urethral meatus
intersection_of: part_of UBERON:0003100 ! female organism
relationship: part_of UBERON:0001334 ! female urethra
property_value: UBPROP:0000001 "The external urethral orifice (urinary meatus) is the external opening of the urethra, from which urine is ejected during urination. It is placed about 2.5 cm behind the glans clitoridis and immediately in front of that of the vagina; it usually assumes the form of a short, sagittal cleft with slightly raised margins. To its left and right are the openings of the Skene's ducts." xsd:string {source="Wikipedia:External_urethral_orifice_(female)"}

[Term]
id: UBERON:0006566
name: left ventricle myocardium
namespace: uberon
def: "A myocardium that is part of a left ventricle of a heart." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
synonym: "left ventricular myocardium" EXACT [FMA:9558]
synonym: "myocardium of left ventricle" EXACT [FMA:9558]
xref: EMAPA:17339
xref: FMA:9558
xref: MA:0002983
xref: SCTID:362021000
is_a: UBERON:0001083 ! myocardium of ventricle
intersection_of: UBERON:0001083 ! myocardium of ventricle
intersection_of: part_of UBERON:0002084 ! heart left ventricle
relationship: continuous_with UBERON:0003618 ! aorta tunica media
relationship: part_of UBERON:0002084 ! heart left ventricle
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Myocardium of ventricle which is continuous with the tunica media of aorta." xsd:string {source="FMA:9558"}

[Term]
id: UBERON:0006567
name: right ventricle myocardium
namespace: uberon
def: "A myocardium that is part of a right ventricle of a heart." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
synonym: "myocardium of right ventricle" EXACT [FMA:9535]
synonym: "right ventricular myocardium" EXACT [FMA:9535]
xref: EMAPA:17342
xref: FMA:9535
xref: MA:0002984
xref: SCTID:362020004
is_a: UBERON:0001083 ! myocardium of ventricle
intersection_of: UBERON:0001083 ! myocardium of ventricle
intersection_of: part_of UBERON:0002080 ! heart right ventricle
relationship: continuous_with UBERON:0006563 ! tunica media of pulmonary trunk
relationship: part_of UBERON:0002080 ! heart right ventricle
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Myocardium of ventricle which is continuous with the tunica media of the pulmonary trunk." xsd:string {source="FMA:9535"}

[Term]
id: UBERON:0006570
name: trabecula carnea of right ventricle
namespace: uberon
def: "A trabecula carnea that is part of a heart right ventricle." [OBOL:automatic]
synonym: "trabeculae carneae (ventriculus dexter)" EXACT [FMA:7270]
xref: FMA:7270
xref: SCTID:192373001
is_a: UBERON:0002511 ! trabecula carnea
intersection_of: UBERON:0002511 ! trabecula carnea
intersection_of: part_of UBERON:0002080 ! heart right ventricle
relationship: part_of UBERON:0002080 ! heart right ventricle

[Term]
id: UBERON:0006571
name: trabecula carnea of left ventricle
namespace: uberon
def: "A trabecula carnea that is part of a heart left ventricle." [OBOL:automatic]
synonym: "trabeculae carneae (ventriculus sinister)" EXACT [FMA:7271]
xref: FMA:7271
xref: SCTID:190344008
is_a: UBERON:0002511 ! trabecula carnea
intersection_of: UBERON:0002511 ! trabecula carnea
intersection_of: part_of UBERON:0002084 ! heart left ventricle
relationship: part_of UBERON:0002084 ! heart left ventricle

[Term]
id: UBERON:0006574
name: pectinate line
namespace: uberon
def: "The pectinate line (anocutaneous line, dentate line, anorectal junction) is a line which divides the upper 2/3rds and lower 1/3rd of the anal canal. Developmentally, this line represents the hindgut-proctodeum junction. It is an important anatomical landmark, and several distinctions can be made based upon the location of a structure relative to this line:." [Wikipedia:Pectinate_line]
synonym: "dentate line" RELATED [Wikipedia:Pectinate_line]
synonym: "Hilton's 'white line'" RELATED [EMAPA:19159]
synonym: "linea anocutanea" RELATED OMO:0003011 [Wikipedia:Pectinate_line]
synonym: "linea pectinata canalis analis" EXACT OMO:0003011 [FMA:75383, FMA:TA]
synonym: "pectinate line of anal canal" EXACT [FMA:75383]
synonym: "recto-anal junction" RELATED [Wikipedia:Pectinate_line]
synonym: "site of anal membrane" RELATED [EMAPA:19159]
xref: EMAPA:19159
xref: FMA:75383
xref: NCIT:C34245
xref: SCTID:245445008
xref: UMLS:C0821671 {source="ncithesaurus:Pectinate_Line"}
xref: Wikipedia:Pectinate_line
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:8410024 ! intestinal junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0000931 ! proctodeum
intersection_of: connects UBERON:0001046 ! hindgut
relationship: connects UBERON:0000931 ! proctodeum
relationship: connects UBERON:0001046 ! hindgut
relationship: part_of UBERON:0000159 ! anal canal
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/7b/Hemorrhoid.png" xsd:anyURI
property_value: UBPROP:0000012 "FMA also has FMA:29321 but it's not clear how this differs" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0006595
name: presumptive endoderm
namespace: uberon
def: "Presumptive structure of the blastula that will develop into endoderm." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
xref: AAO:0000471
xref: EFO:0003437
xref: TAO:0000416
xref: ZFA:0000416
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0000925 ! endoderm
intersection_of: part_of UBERON:0000307 ! blastula
relationship: has_potential_to_develop_into UBERON:0000925 ! endoderm
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000307 ! blastula

[Term]
id: UBERON:0006596
name: presumptive blood
namespace: uberon
subset: efo_slim
synonym: "future blood" EXACT []
xref: AAO:0000468
xref: EFO:0003439
xref: TAO:0000568
xref: ZFA:0000568
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0000178 ! blood
relationship: has_potential_to_develop_into UBERON:0000178 ! blood

[Term]
id: UBERON:0006598
name: presumptive structure
namespace: uberon
def: "Portion of embryonic tissue determined by fate mapping to become a structure." [GOC:CVS, GOC:YMB, ZFA:0001116]
synonym: "future structure" EXACT []
synonym: "presumptive structures" EXACT [ZFA:0001116]
xref: AAO:0000479
xref: TAO:0001116
xref: ZFA:0001116
is_a: UBERON:0002050 ! embryonic structure
intersection_of: UBERON:0005423 ! developing anatomical structure
intersection_of: has_potential_to_develop_into UBERON:0000061 ! anatomical structure
intersection_of: part_of UBERON:0000922 ! embryo
relationship: has_potential_to_develop_into UBERON:0000061 ! anatomical structure
property_value: editor_note "Consider merging with anlage" xsd:string

[Term]
id: UBERON:0006601
name: presumptive ectoderm
namespace: uberon
def: "Presumptive structure of the blastula that will develop into ectoderm." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
synonym: "presumptive epidermis" RELATED [ZFA:0001376]
xref: AAO:0000470
xref: EFO:0003466
xref: TAO:0001376
xref: XAO:0004132
xref: ZFA:0001376
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0000924 ! ectoderm
intersection_of: part_of UBERON:0000307 ! blastula
relationship: has_potential_to_develop_into UBERON:0000924 ! ectoderm
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000307 ! blastula

[Term]
id: UBERON:0006603
name: presumptive mesoderm
namespace: uberon
def: "Presumptive structure of the blastula that will develop into mesoderm." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
xref: AAO:0000476
xref: EFO:0003467
xref: TAO:0001377
xref: ZFA:0001377
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0000926 ! mesoderm
intersection_of: part_of UBERON:0000307 ! blastula
relationship: has_potential_to_develop_into UBERON:0000926 ! mesoderm
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000307 ! blastula

[Term]
id: UBERON:0006642
name: muscle layer of oviduct
namespace: uberon
def: "A muscle layer that is part of a fallopian tube." [OBOL:automatic]
synonym: "muscle layer of fallopian tube" EXACT [FMA:18318]
synonym: "muscle layer of oviduct" EXACT [FMA:18318]
synonym: "muscle layer of uterine tube" EXACT [FMA:18318]
synonym: "muscular coat of uterine tube" EXACT [FMA:18318]
synonym: "muscular layer of uterine tube" EXACT [FMA:18318]
synonym: "muscularis of uterine tube" EXACT [FMA:18318]
synonym: "tunica muscularis (Tuba uterina)" EXACT [FMA:18318]
synonym: "tunica muscularis tubae uterinae" EXACT OMO:0003011 [FMA:18318, FMA:TA]
synonym: "uterine tubal muscularis" EXACT [FMA:18318]
xref: EMAPA:29046
xref: FMA:18318
xref: SCTID:259488000
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0006660 ! muscular coat
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0003889 ! fallopian tube
relationship: part_of UBERON:0003889 ! fallopian tube

[Term]
id: UBERON:0006645
name: adventitia of epididymis
namespace: uberon
def: "An adventitia that is part of a epididymis." [OBOL:automatic]
synonym: "epididymis adventitia" EXACT [FMA:19136]
xref: EMAPA:30443
xref: FMA:19136
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0005742 ! adventitia
intersection_of: UBERON:0005742 ! adventitia
intersection_of: part_of UBERON:0001301 ! epididymis
relationship: part_of UBERON:0001301 ! epididymis

[Term]
id: UBERON:0006646
name: muscle layer of epididymis
namespace: uberon
def: "A muscle layer that is part of a epididymis." [OBOL:automatic]
xref: EMAPA:30747
xref: FMA:19149
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0006660 ! muscular coat
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0001301 ! epididymis
relationship: part_of UBERON:0001301 ! epididymis

[Term]
id: UBERON:0006647
name: adventitia of ductus deferens
namespace: uberon
def: "An adventitia that is part of a vas deferens." [OBOL:automatic]
synonym: "adventitia of deferent duct" EXACT [FMA:19238]
synonym: "adventitia of ductus deferens" EXACT [FMA:19238]
synonym: "adventitia of vas deferens" EXACT [FMA:19238]
synonym: "deferent ductal adventitia" EXACT [FMA:19238]
synonym: "tunica adventitia (ductus deferens)" EXACT [FMA:19238]
synonym: "tunica adventitia ductus deferentis" EXACT OMO:0003011 [FMA:19238, FMA:TA]
xref: EMAPA:29767
xref: FMA:19238
xref: SCTID:299803005
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0005742 ! adventitia
intersection_of: UBERON:0005742 ! adventitia
intersection_of: part_of UBERON:0001000 ! vas deferens
relationship: part_of UBERON:0001000 ! vas deferens

[Term]
id: UBERON:0006648
name: adventitia of seminal vesicle
namespace: uberon
def: "An adventitia that is part of a seminal vesicle." [OBOL:automatic]
synonym: "adventitia of seminal gland" EXACT [FMA:19403]
synonym: "seminal vesicle adventitia" EXACT [FMA:19403]
synonym: "tunica adventitia (vesicula seminalis)" EXACT [FMA:19403]
synonym: "tunica adventitia glandulae vesiculosae" EXACT OMO:0003011 [FMA:19403, FMA:TA]
xref: EMAPA:29775
xref: FMA:19403
xref: SCTID:252406002
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0005742 ! adventitia
intersection_of: UBERON:0005742 ! adventitia
intersection_of: part_of UBERON:0000998 ! seminal vesicle
relationship: part_of UBERON:0000998 ! seminal vesicle

[Term]
id: UBERON:0006653
name: glans clitoris
namespace: uberon
def: "Erectile tissue at the end of the clitoris, which is continuous with the intermediate part of the vestibulovaginal bulbs[BTO]. The clitoral glans (glans clitoridis) is an external portion of the clitoris[WP]." [BTO:0003117, Wikipedia:Clitoral_glans]
synonym: "clitoris glans" EXACT [FMA:19999]
synonym: "glans clitoridis" RELATED [Wikipedia:Clitoral_glans]
synonym: "glans clitoris" RELATED [Wikipedia:Clitoral_glans]
synonym: "glans of clitoris" EXACT [FMA:19999]
xref: BTO:0003117
xref: EMAPA:19170
xref: EMAPA:30829
xref: FMA:19999
xref: NCIT:C32681
xref: SCTID:362241002
xref: UMLS:C0227769 {source="ncithesaurus:Glans_Clitoris"}
xref: Wikipedia:Clitoral_glans
is_a: UBERON:0008324 ! erectile tissue
is_a: UBERON:0035651 ! glans
intersection_of: UBERON:0035651 ! glans
intersection_of: part_of UBERON:0002411 ! clitoris
relationship: develops_from UBERON:0013240 {source="cjm"} ! future glans clitoris
relationship: part_of UBERON:0002411 ! clitoris
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/8/8c/Clitoris_inner_anatomy.gif" xsd:anyURI

[Term]
id: UBERON:0006660
name: muscular coat
namespace: uberon
def: "A region of muscle in many organs in the vertebrate body, adjacent to the submucosa membrane. It is responsible for gut movement such as peristalsis." [Wikipedia:Muscular_layer]
synonym: "muscular coat" RELATED [Wikipedia:Muscularis_externa]
synonym: "muscular layer" EXACT [OBOL:automatic]
synonym: "muscularis" RELATED []
synonym: "muscularis externa" RELATED [BTO:0004838]
synonym: "muscularis layer" EXACT [FMA:45634]
synonym: "muscularis propria" RELATED [Wikipedia:Muscularis_externa]
synonym: "transverse muscular fibers" RELATED [Wikipedia:Muscularis_externa]
synonym: "tunica externa" RELATED [BTO:0004838]
synonym: "tunica muscularis" EXACT OMO:0003011 [BTO:0004838]
synonym: "tunica muscularis" RELATED [Wikipedia:Muscularis_externa]
xref: BTO:0004838
xref: SCTID:86915006
xref: UMLS:C0225358 {source="ncithesaurus:Muscle_Layer"}
xref: Wikipedia:Muscular_layer
is_a: UBERON:0018260 ! layer of muscle tissue
relationship: adjacent_to UBERON:0000009 ! submucosa
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
property_value: editor_note "currently this class conflates a generic layer of muscle and a specific layer found lining the digestive tract (the muscularis externa), typically composed of circular and longitudinal layers (although this varies)" xsd:string
property_value: RO:0002171 UBERON:0000009
property_value: RO:0002171 UBERON:0006676
property_value: UBPROP:0000001 "An outer layer of smooth muscle surrounding a hollow or tubular organ as the bladder, esophagus, large intestine, small intestine, stomach, ureter, uterus, and vagina that often consists of an inner layer of circular fibers serving to narrow the lumen of the organ and an outer layer of longitudinal fibers serving to shorten its length[BTO]." xsd:string {source="BTO:0004838"}
property_value: UBPROP:0000008 "typically smooth muscle, but there may be exceptions - in the upper esophagus, part of the externa is skeletal muscle, rather than smooth muscle." xsd:string

[Term]
id: UBERON:0006670
name: central tendon of diaphragm
namespace: uberon
def: "The three-lobed cloverleaf-shaped aponeurosis situated at the center of the diaphragm; the central tendon is fused with the fibrous pericardium that provides attachment for the muscle fibers." [MGI:csmith, MP:0012061]
subset: pheno_slim
synonym: "central tendon" EXACT [FMA:58279]
synonym: "centrum tendineum" EXACT [FMA:58279]
synonym: "centrum tendineum diaphragmatis" EXACT OMO:0003011 [FMA:58279, FMA:TA]
xref: EMAPA:17702
xref: FMA:58279
xref: NCIT:C34119
xref: SCTID:244943002
xref: UMLS:C0230162 {source="ncithesaurus:Central_Tendon_of_the_Diaphragm"}
xref: VHOG:0001399
xref: Wikipedia:Central_tendon_of_diaphragm
is_a: UBERON:0000043 ! tendon
is_a: UBERON:0003570 ! respiratory system connective tissue
is_a: UBERON:0003837 ! thoracic segment connective tissue
relationship: attaches_to UBERON:0002359 ! fibrous pericardium
relationship: develops_from UBERON:0006239 ! future central tendon
relationship: immediate_transformation_of UBERON:0006239 {evidence="definitional"} ! future central tendon
relationship: part_of UBERON:0001103 {source="VHOG"} ! diaphragm
property_value: UBPROP:0000003 "In mammals, the diaphragm muscle divides the thoracoabdominal cavity into thorax and abdomen. In most mammals, the diaphragm is a flat sheet with muscle fibers radiating outward from a central tendon, and the diaphragm's apposition to the cranial surface of the liver gives it a dome-shape. Muscle fiber contraction reduces the curvature of the dome, thereby expanding the thoracic cavity and aspirating air into the lungs.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001399", ontology="VHOG", source="DOI:10.1016/j.resp.2006.06.003", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0006675
name: venous valve
namespace: uberon
def: "A valve that is part of a vein." [OBOL:automatic]
synonym: "valve of vein" EXACT [FMA:68095]
xref: FMA:68095
xref: MESH:D055422 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
is_a: UBERON:0003978 ! valve
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0003978 ! valve
intersection_of: part_of UBERON:0001638 ! vein
relationship: part_of UBERON:0001638 ! vein

[Term]
id: UBERON:0006677
name: surface of epithelium
namespace: uberon
def: "An anatomical boundary that adjacent_to a epithelium." [OBOL:automatic]
synonym: "epithelium surface" EXACT [FMA:70997]
xref: FMA:70997
is_a: UBERON:0036215 ! anatomical surface region
intersection_of: UBERON:0036215 ! anatomical surface region
intersection_of: bounding_layer_of UBERON:0000483 ! epithelium
relationship: bounding_layer_of UBERON:0000483 ! epithelium
relationship: part_of UBERON:0000483 ! epithelium

[Term]
id: UBERON:0006686
name: spinal vein
namespace: uberon
def: "A vein that is part of a vertebral column." [OBOL:automatic]
synonym: "spinal branch" RELATED [FMA:76735]
synonym: "vena spinalis" EXACT OMO:0003011 [FMA:76735, FMA:TA]
xref: EMAPA:18255
xref: FMA:76735
xref: MA:0002108
xref: SCTID:181376008
xref: Wikipedia:Spinal_veins
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0001130 ! vertebral column
relationship: part_of UBERON:0001130 ! vertebral column

[Term]
id: UBERON:0006692
name: vertebral canal
namespace: uberon
def: "A conduit enclosed within the vertebral foramen of the vertebrae through which the spinal cord passes." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Spinal_canal]
subset: pheno_slim
synonym: "c. vertebralis" RELATED OMO:0003011 [Wikipedia:Spinal_canal]
synonym: "foramen vertebrale" RELATED [AAO:0000693]
synonym: "neural canal" RELATED [AAO:0000693]
synonym: "spinal canal" RELATED [AAO:0000693]
synonym: "spinal cavity" RELATED [Wikipedia:Spinal_canal]
synonym: "vertebral canal" RELATED [Wikipedia:Spinal_canal]
xref: AAO:0000693
xref: FMA:9680
xref: GAID:242
xref: MESH:D013115 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: NCIT:C33869
xref: NCIT:C34221
xref: SCTID:361746009
xref: UMLS:C0037922 {source="ncithesaurus:Vertebral_Canal"}
xref: UMLS:C1522467 {source="ncithesaurus:Neural_Canal"}
xref: Wikipedia:Spinal_canal
is_a: UBERON:0004111 ! anatomical conduit
intersection_of: UBERON:0004111 ! anatomical conduit
intersection_of: conduit_for UBERON:0002240 ! spinal cord
intersection_of: lumen_of UBERON:0001130 ! vertebral column
relationship: conduit_for UBERON:0002240 ! spinal cord
relationship: lumen_of UBERON:0001130 ! vertebral column
relationship: part_of UBERON:0001130 ! vertebral column
relationship: surrounds UBERON:0002240 ! spinal cord
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray82.png" xsd:anyURI
property_value: editor_note "TODO - check neural vs vertebral canal; embryonic vs adult?" xsd:string
property_value: UBPROP:0000001 "Canal formed by the vertebral centra ventrally, the pedicels laterally, and the neural arches dorsally that encloses and protects the spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000693", ontology="AAO", source="AAO:LAP"}

[Term]
id: UBERON:0006761
name: corneo-scleral junction
namespace: uberon
def: "The edge of the cornea where it joins the sclera; the limbus is a common site for the occurrence of corneal epithelial neoplasm." [MP:0013477]
comment: This location has parts such as blood vessels etc. See PMC2868485, http://www.ncbi.nlm.nih.gov/pubmed/2695343
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
subset: vertebrate_core
synonym: "cornea limbus" EXACT []
synonym: "corneal limbus" EXACT [FMA:58342, GAID:896]
synonym: "corneal-scleral limbus" EXACT [PMID:17051547]
synonym: "corneoscleral junction" EXACT [GAID:896]
synonym: "limbus corneae" EXACT OMO:0003011 [Wikipedia:Corneal_limbus]
synonym: "limbus corneae" RELATED OMO:0003011 [Wikipedia:Corneal_limbus]
synonym: "sclerocorneal junction" EXACT [FMA:58342]
synonym: "sclerocorneal limbus" EXACT [GAID:896]
xref: EFO:0001403
xref: EMAPA:37835 {source="MA:th"}
xref: FMA:58342
xref: GAID:896
xref: MESH:D016850
xref: SCTID:63716004
xref: Wikipedia:Corneal_limbus
xref: ZFA:0005570
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0007651 ! anatomical junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0000964 ! cornea
intersection_of: connects UBERON:0001773 ! sclera
relationship: connects UBERON:0000964 ! cornea
relationship: connects UBERON:0001773 ! sclera
relationship: part_of UBERON:0000019 ! camera-type eye
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/3d/Limbus.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0006799
name: glandular epithelium
namespace: uberon
def: "An epithelium that is composed primarily of secretory cells." [http://orcid.org/0000-0002-6601-2165]
xref: BTO:0002991
xref: NCIT:C43370
xref: NCIT:C45715
xref: UMLS:C0682578 {source="ncithesaurus:Glandular_Epithelium"}
xref: UMLS:C1708242 {source="ncithesaurus:Glandular_Epithelial_Tissue"}
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell
relationship: composed_primarily_of CL:0000150 ! glandular epithelial cell
property_value: editor_note "consider splitting epithelium from epithelial tissue" xsd:string

[Term]
id: UBERON:0006815
name: areolar connective tissue
namespace: uberon
def: "Loose connective tissue located at the outer and inner layers of organs. Examples: submucosal connective tissue, tunica adventitia of artery, papillary dermis, superficial fascia of dorsum of hand." [FMA:63897]
synonym: "areolar tissue" RELATED []
synonym: "loose areolar connective tissue" EXACT [FMA:63897]
synonym: "loose connective tissue" RELATED [AAO:0000027]
xref: AAO:0000027
xref: FMA:63897
xref: SCTID:68477002
is_a: UBERON:0011825 {source="FMA"} ! loose connective tissue
relationship: has_part CL:1000303 {source="FMA"} ! fibroblast of areolar connective tissue
relationship: part_of UBERON:0000030 ! lamina propria
relationship: protects UBERON:0000062 ! organ
property_value: UBPROP:0000001 "Also known as loose connective tissue. A pliable, mesh-like tissue with a fluid matrix that functions to cushion and protect body organs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000027", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000002 "relationship loss: subclass connective tissue proper (AAO:0000099)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000027", ontology="AAO"}
property_value: UBPROP:0000009 "cushions body organs" xsd:string {source="AAO"}

[Term]
id: UBERON:0006828
name: trabecula carnea of atrium
namespace: uberon
def: "The supporting bundles of muscular fibers lining the walls of the atria[MP]." [MP:0010581]
is_a: UBERON:0002511 ! trabecula carnea
intersection_of: UBERON:0002511 ! trabecula carnea
intersection_of: part_of UBERON:0002081 ! cardiac atrium
relationship: part_of UBERON:0002081 ! cardiac atrium
property_value: editor_note "Not present in any AO. Note that WP states that trabecular carnea are ventricular and 'They should not be confused with the pectinate muscles, which are present in the right and left atria only'" xsd:string

[Term]
id: UBERON:0006834
name: uterus or analog
namespace: uberon
def: "A subdivision of a the reproductive tract in a female organism that is the site of embryo development." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "uterus" BROAD SENSU [FBbt:00004924]
xref: FBbt:00004924 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: TADS:0000421
xref: WBbt:0006760
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0013522 ! subdivision of tube
intersection_of: UBERON:0013522 ! subdivision of tube
intersection_of: site_of GO:0009790 ! embryo development
relationship: only_in_taxon NCBITaxon:33208 ! Metazoa
relationship: part_of UBERON:0000474 ! female reproductive system
relationship: site_of GO:0009790 ! embryo development

[Term]
id: UBERON:0006841
name: central vein of liver
namespace: uberon
def: "Vein that is central to a lobule in the liver." [ZFA:0005168]
subset: human_reference_atlas
subset: vertebrate_core
synonym: "central vein" BROAD [ZFA:0005168]
synonym: "terminal branch of hepatic vein" EXACT [FMA:17544]
synonym: "terminal hepatic venule" EXACT [FMA:17544]
synonym: "vena centralis (hepar)" EXACT [FMA:17544]
xref: FMA:17544
xref: NCIT:C32281
xref: SCTID:272023004
xref: TAO:0005168
xref: Wikipedia:Central_veins_of_liver
xref: ZFA:0005168
is_a: UBERON:0013126 ! vein of abdomen
is_a: UBERON:0015796 ! liver blood vessel
relationship: part_of UBERON:0004647 ! liver lobule
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0006846
name: surface groove
namespace: uberon
def: "A furrow or an incomplete tube." [AEO:0000161, AEO:JB, https://github.com/obophenotype/human-developmental-anatomy-ontology/issues/4]
comment: Surface groove is modelled as immaterial - see https://github.com/obophenotype/uberon/issues/2667 for discussion
subset: grouping_class
synonym: "groove" RELATED [AEO:0000161]
xref: AEO:0000161
xref: EHDAA2_RETIRED:0003161
is_a: UBERON:0000466 ! immaterial anatomical entity
relationship: has_quality PATO:0002255 ! grooved
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/2667" xsd:string

[Term]
id: UBERON:0006855
name: muscular coat of ureter
namespace: uberon
def: "A muscular coat that is part of a ureter." [OBOL:automatic]
synonym: "muscular coat of ureter" EXACT [FMA:15893]
synonym: "muscular layer of ureter" EXACT [FMA:15893]
synonym: "muscularis of ureter" EXACT [FMA:15893]
synonym: "tunica muscularis (ureter)" EXACT OMO:0003011 [FMA:TA]
synonym: "tunica muscularis ureteris" EXACT OMO:0003011 [FMA:TA]
synonym: "ureteral smooth muscle layer" RELATED [EMAPA:28567]
xref: EMAPA:28811
xref: FMA:15893
xref: MA:0002654
xref: SCTID:3563003
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0006660 ! muscular coat
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0000056 ! ureter
relationship: part_of UBERON:0009916 {source="FMA"} ! wall of ureter

[Term]
id: UBERON:0006866
name: terminal part of digestive tract
namespace: uberon
def: "The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus." [http://orcid.org/0000-0002-6601-2165]
synonym: "rectal part of digestive tract" RELATED []
synonym: "rectum" NARROW [FBbt:00005756]
synonym: "terminal section of digestive tract" RELATED []
xref: FBbt:00005756 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: WBbt:0005773
is_a: UBERON:0004921 ! subdivision of digestive tract
relationship: continuous_with UBERON:0001245 ! anus
relationship: develops_from UBERON:0001046 ! hindgut
property_value: curator_notes "this class is the superclass of 'rectum', which is currently reserved for the vertebrate structure. May be merged in future." xsd:string

[Term]
id: UBERON:0006868
name: seminal fluid secreting gland
namespace: uberon
def: "A gland that secretes a seminal fluid." [OBOL:automatic]
subset: grouping_class
subset: organ_slim
xref: FBbt:00004958 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: WBbt:0006870
is_a: UBERON:0005399 ! male reproductive gland
intersection_of: UBERON:0002530 ! gland
intersection_of: produces UBERON:0006530 ! seminal fluid
relationship: part_of UBERON:0006947 ! male genital duct
relationship: produces UBERON:0006530 ! seminal fluid

[Term]
id: UBERON:0006876
name: vasculature of organ
namespace: uberon
def: "A vasculature that is part of a organ." [OBOL:automatic]
subset: non_informative
synonym: "organ vasculature" EXACT [FMA:74612]
synonym: "set of blood vessels of organ" EXACT [FMA:74612]
xref: FMA:74612
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0000062 ! organ
relationship: part_of UBERON:0000062 ! organ

[Term]
id: UBERON:0006877
name: vasculature of liver
namespace: uberon
def: "A vasculature that is part of a liver." [OBOL:automatic]
subset: pheno_slim
synonym: "hepatic vascular element" RELATED [EMAPA:35501]
synonym: "hepatic vasculature" EXACT [FMA:73748]
synonym: "liver vascular element" RELATED [EMAPA:35501]
synonym: "liver vascular system" RELATED [EHDAA2:0003454]
xref: EHDAA2:0003454
xref: EMAPA:35501
xref: FMA:73748
is_a: UBERON:0002201 ! vasculature of trunk
is_a: UBERON:0006876 ! vasculature of organ
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0002107 ! liver
relationship: part_of UBERON:0002107 ! liver
property_value: UBPROP:0000012 "the EHDAA2 term and the FMA term may not be exact equivalents - check" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0006904
name: head mesenchyme from mesoderm
namespace: uberon
def: "A head mesenchyme that develops_from a mesoderm." [OBOL:automatic]
subset: efo_slim
subset: vertebrate_core
synonym: "cranial mesoderm" RELATED [UBERON:0005280]
synonym: "head mesenchyme derived from mesoderm" EXACT []
synonym: "head mesenchyme from head mesoderm" EXACT [EHDAA2:0001118]
synonym: "head mesenchyme from mesoderm" EXACT []
synonym: "head mesoderm" RELATED [AAO:0011051, UBERON:0005280]
synonym: "mesenchyme derived from head mesoderm" EXACT [EHDAA:1057]
synonym: "mesenchyme from head mesoderm" EXACT []
xref: AAO:0011051
xref: EFO:0003337
xref: EFO:0003603
xref: EHDAA2:0001118
xref: EHDAA:655
xref: EMAPA:16099
xref: EMAPA_RETIRED:16270
xref: FMA:293859
xref: TAO:0000998
xref: VHOG:0000185
xref: XAO:0000053
xref: ZFA:0000998
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005253 {source="ZFA"} ! head mesenchyme
intersection_of: UBERON:0005253 ! head mesenchyme
intersection_of: develops_from UBERON:0000926 ! mesoderm
relationship: develops_from UBERON:0003063 {source="EHDAA2", source="XAO"} ! prechordal plate
property_value: editor_note "merged in 'head mesoderm' from XAO/AAO and EFO here. Partially implements https://github.com/obophenotype/uberon/wiki/The-neural-crest NC meeting scheme" xsd:string

[Term]
id: UBERON:0006905
name: mandibular process mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a mandibular prominence." [OBOL:automatic]
synonym: "mesenchyme of mandibular process" EXACT [EMAPA:17357]
synonym: "mesenchyme of mandibular prominence" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: EHDAA2:0001062
xref: EHDAA:5861
xref: EHDAA:5873
xref: EMAPA:17357
is_a: UBERON:0005253 ! head mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0005867 ! mandibular prominence
relationship: part_of UBERON:0005867 ! mandibular prominence

[Term]
id: UBERON:0006909
name: lumen of digestive tract
namespace: uberon
def: "An anatomical space that surrounded_by a digestive tract." [OBOL:automatic]
synonym: "digestive tract lumen" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "gut cavity" EXACT [BTO:0000349]
synonym: "gut lumen" EXACT [FMA:45677]
synonym: "lumen of alimentary tract" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "lumen of digestive tract" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "lumen of gut" EXACT [FMA:45677]
xref: BTO:0000349
xref: EMAPA:32908
xref: FMA:45677
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0001555 ! digestive tract
relationship: luminal_space_of UBERON:0001555 ! digestive tract
relationship: part_of UBERON:0001555 ! digestive tract

[Term]
id: UBERON:0006913
name: lip epithelium
namespace: uberon
def: "An epithelium that is part of a lip." [OBOL:automatic]
xref: BTO:0004468
xref: TAO:0005334
xref: ZFA:0005334
is_a: UBERON:0003929 ! digestive tract epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001833 ! lip
relationship: part_of UBERON:0001833 ! lip
property_value: UBPROP:0000001 "The thick, high squamous-stratified epithelium that covers the lips. It contains abundant melanocytes, many mucous cells and has well differentiated taste buds.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005334", ontology="TAO", source="ZFIN:ZDB-PUB-060921-12"}

[Term]
id: UBERON:0006914
name: squamous epithelium
namespace: uberon
def: "An epithelium characterised by its most superficial layer consisting of squamous epithelial cells." [Wikipedia:Squamous_epithelium]
xref: BTO:0002072
xref: NCIT:C12848
xref: SCTID:40118003
xref: UMLS:C0221909 {source="ncithesaurus:Squamous_Epithelium"}
xref: Wikipedia:Squamous_epithelium
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: has_part CL:0000076 ! squamous epithelial cell
relationship: has_part CL:0000076 ! squamous epithelial cell
property_value: UBPROP:0000012 "FBbt:00007028 (squamous epithelium) A type of epithelium that is made up of flattened cells which are arranged with their long axes in the plane of the epithelium" xsd:string {external_ontology="FBbt"}

[Term]
id: UBERON:0006915
name: stratified squamous epithelium
namespace: uberon
def: "Multilaminar epithelium which consists of more than one layer of squamous cells only one layer of which is in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, epithelium of wall of esophagus.[FMA]." [FMA:45563, Wikipedia:Stratified_squamous_epithelium]
subset: pheno_slim
synonym: "epithelium stratificatum squamosum" EXACT [FMA:45563]
xref: FMA:45563
xref: NCIT:C13180
xref: UMLS:C0836131 {source="ncithesaurus:Stratified_Squamous_Epithelium"}
xref: Wikipedia:Stratified_squamous_epithelium
is_a: UBERON:0000486 ! multilaminar epithelium
is_a: UBERON:0006914 ! squamous epithelium
intersection_of: UBERON:0000486 ! multilaminar epithelium
intersection_of: has_part CL:0000076 ! squamous epithelial cell

[Term]
id: UBERON:0006920
name: esophagus squamous epithelium
namespace: uberon
def: "A squamous epithelium that is part of a esophagus." [OBOL:automatic]
subset: pheno_slim
synonym: "esophageal squamous epithelium" RELATED [OBOL:automatic]
synonym: "squamous epithelium of esophagus" RELATED [OBOL:automatic]
synonym: "squamous oesophageal epithelium" RELATED [MA:0001567]
xref: BTO:0003635
xref: CALOHA:TS-1250
xref: EMAPA:35324
xref: MA:0001567
xref: NCIT:C49222
xref: UMLS:C1707950 {source="ncithesaurus:Esophageal_Squamous_Epithelium"}
is_a: UBERON:0001976 ! epithelium of esophagus
is_a: UBERON:0006914 ! squamous epithelium
intersection_of: UBERON:0006914 ! squamous epithelium
intersection_of: part_of UBERON:0001043 ! esophagus
property_value: UBPROP:0000012 "MA introduces basal and squamous subtypes of esophagus epithelium; consider adding the FMA class 'epithelium of esophagus' here, because it is classified as squamous. BTO also has a singleton subclass" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0006921
name: stomach squamous epithelium
namespace: uberon
def: "A squamous epithelium that is part of a stomach." [OBOL:automatic]
subset: pheno_slim
xref: EMAPA:35824
xref: MA:0001611
is_a: UBERON:0000487 ! simple squamous epithelium
is_a: UBERON:0001276 ! epithelium of stomach
intersection_of: UBERON:0006914 ! squamous epithelium
intersection_of: part_of UBERON:0000945 ! stomach

[Term]
id: UBERON:0006924
name: stomach glandular epithelium
namespace: uberon
def: "A glandular epithelium that lines the stomach. The stomach's glandular epithelium is characterized by the presence of gastric glands." [ISBN:0073040584]
subset: pheno_slim
synonym: "epithelium of gastric gland" NARROW [FMA:63458]
synonym: "gastric gland epithelium" RELATED [FMA:63458]
xref: EMAPA:17623
xref: EMAPA:35814
xref: FMA:63458
xref: MA:0002784
is_a: UBERON:0001276 ! epithelium of stomach
is_a: UBERON:0006929 {source="FMA"} ! glandular columnar epithelium
intersection_of: UBERON:0006799 ! glandular epithelium
intersection_of: part_of UBERON:0000945 ! stomach
relationship: has_part UBERON:0000325 ! gastric gland
relationship: part_of UBERON:0006931 ! stomach glandular region mucosa
property_value: editor_note "we follow Kardong in treating the glandular epithelium as a distinct entity, and thus as an epithelium which has glands; FMA has 'epithelium of gastric gland', which is part of the gastric gland." xsd:string

[Term]
id: UBERON:0006925
name: digestive system gland
namespace: uberon
def: "Any gland that is part of the digestive system." [UBERON:cjm]
subset: organ_slim
synonym: "digestive gland" RELATED [BTO:0000345]
xref: AAO:0000130
xref: BTO:0000345
is_a: UBERON:0002368 ! endocrine gland
is_a: UBERON:0013765 ! digestive system element
intersection_of: UBERON:0002368 ! endocrine gland
intersection_of: part_of UBERON:0001007 ! digestive system

[Term]
id: UBERON:0006929
name: glandular columnar epithelium
namespace: uberon
def: "Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA]." [FMA:64800]
xref: FMA:64800
xref: NCIT:C13182
xref: UMLS:C0225337 {source="ncithesaurus:Columnar_Epithelium"}
is_a: UBERON:0000485 ! simple columnar epithelium
is_a: UBERON:0006799 ! glandular epithelium
intersection_of: UBERON:0000485 ! simple columnar epithelium
intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell

[Term]
id: UBERON:0006930
name: glandular cuboidal epithelium
namespace: uberon
xref: FMA:66809
is_a: UBERON:0000484 ! simple cuboidal epithelium
is_a: UBERON:0006799 ! glandular epithelium
intersection_of: UBERON:0000484 ! simple cuboidal epithelium
intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell

[Term]
id: UBERON:0006931
name: stomach glandular region mucosa
namespace: uberon
def: "Stomach mucosa that is lined with glandular epithelium and part of a stomach glandular region." [http://orcid.org/0000-0002-6601-2165]
synonym: "stomach glandular region glandular mucous membrane" EXACT [EMAPA:27167]
xref: EMAPA:27167
xref: MA:0001614
is_a: UBERON:0001199 ! mucosa of stomach
intersection_of: UBERON:0001199 ! mucosa of stomach
intersection_of: part_of UBERON:0011953 ! stomach glandular region
relationship: part_of UBERON:0011953 ! stomach glandular region

[Term]
id: UBERON:0006934
name: sensory epithelium
namespace: uberon
def: "Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue." [BTO:0000314]
synonym: "neuroepithelium" RELATED INCONSISTENT [BTO:0000314]
xref: CALOHA:TS-0682
xref: FMA:62410
xref: SCTID:309045006
is_a: UBERON:0000488 ! atypical epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: has_part CL:0000098 ! sensory epithelial cell
relationship: has_part CL:0000098 ! sensory epithelial cell
relationship: part_of UBERON:0000010 ! peripheral nervous system
property_value: UBPROP:0000012 "note that the definition sourced from Dorlands say 'simple columnar', but FMA says atypical" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0006946
name: efferent duct
namespace: uberon
def: "The efferent ducts (or efferent ductules or ductuli efferentes) connect the rete testis with the initial section of the epididymis. The ductuli are unilaminar and composed of columnar ciliated and non-ciliated (absorptive) cells. The ciliated cells serve to stir the luminal fluids, possibly to help ensure homogeneous absorption of water from the fluid produced by the testis, which results in an increase in the concentration of luminal sperm. The epithelium is surrounded by a band of smooth muscle that helps to propel the sperm toward the epididymis." [Wikipedia:Efferent_ducts]
subset: pheno_slim
synonym: "ductuli efferentes testis" RELATED OMO:0003011 [Wikipedia:Efferent_ducts]
synonym: "efferent ductule" EXACT [FMA:19081, Wikipedia:Efferent_ducts]
synonym: "seminal duct" EXACT []
synonym: "vasa efferentia" RELATED [AAO:0010532, Wikipedia:Efferent_ducts]
xref: AAO:0010532
xref: EMAPA:18993
xref: FMA:19081
xref: MA:0000398
xref: NCIT:C32492
xref: UMLS:C0228013 {source="ncithesaurus:Efferent_Ductule"}
xref: Wikipedia:Efferent_ducts
is_a: UBERON:0000025 ! tube
is_a: UBERON:0005904 ! duct of male reproductive system
relationship: channel_for CL:0000019 ! sperm
relationship: channels_from UBERON:0003959 ! rete testis
relationship: channels_into UBERON:0001301 ! epididymis
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0006947 {source="FMA"} ! male genital duct
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg" xsd:anyURI
property_value: UBPROP:0000001 "Any of a group ranging from one to twelve (varies in species) small seminal ducts per testis which transport sperm from the testes to the kidney.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010532", ontology="AAO", source="AAO:BJB"}
property_value: UBPROP:0000008 "There are two basic designs for efferent ductule structure: a) multiple entries into the epididymis, as seen in most large mammals. In humans and other large mammals, there are approximately 15-20 efferent ducts, which also occupy nearly one third of the head of the epididymis. b) single entry, as seen in most small animals such as rodents, whereby the 3-6 ductules merge into a single small ductule prior to entering the epididymis" xsd:string
property_value: UBPROP:0000012 "Check EMAPA" xsd:string {external_ontology="EMAPA"}

[Term]
id: UBERON:0006947
name: male genital duct
namespace: uberon
alt_id: UBERON:0010140
def: "A duct or series of ducts that transports sperm from the gonad. In mammals this is from the seminiferous tubules through rete testis, vas efferentia, epididymis, vas deferens, ejeculatory duct to the urethra." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "sperm duct" EXACT [ZFA:0001268]
synonym: "sperm ducts" EXACT OMO:0003004 [TAO:0001268]
xref: FMA:55678
xref: TAO:0001268
xref: ZFA:0001268
is_a: UBERON:0000025 ! tube
is_a: UBERON:0005904 ! duct of male reproductive system
is_a: UBERON:0015212 ! lateral structure
relationship: channel_for UBERON:0001968 ! semen
relationship: channels_from UBERON:0000473 ! testis
relationship: in_lateral_side_of UBERON:0004054 {source="FMA-abduced-lr"} ! internal male genitalia
relationship: part_of UBERON:0004054 ! internal male genitalia
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI
property_value: UBPROP:0000008 "we use this as a generic grouping class for a number of taxa" xsd:string
property_value: UBPROP:0000012 "in FMA includes as parts: seminal vesicle, efferent ductule (vas efferentia), epididymis, deferent duct (vas deferens), ejaculatory duct" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0006948
name: efferent duct epithelium
namespace: uberon
def: "An epithelium that is part of a efferent duct." [OBOL:automatic]
synonym: "epithelium of efferent ductule of testis" EXACT [FMA:19195]
xref: EMAPA:29747
xref: FMA:19195
xref: MA:0001734
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0034969 ! epithelial layer of duct
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0006946 ! efferent duct
relationship: part_of UBERON:0006946 ! efferent duct

[Term]
id: UBERON:0006953
name: ejaculatory duct epithelium
namespace: uberon
def: "The ejaculatory duct epithelium is composed of cuboidal to columnar cells between or through which project the terminal parts of the ducts of the unicellular prostate glands." [PMID:1238970]
xref: BTO:0002618
xref: EMAPA:29786
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0034969 ! epithelial layer of duct
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000999 ! ejaculatory duct
relationship: part_of UBERON:0000999 ! ejaculatory duct
property_value: editor_note "TODO - split off insect classes" xsd:string

[Term]
id: UBERON:0006955
name: uterine epithelium
namespace: uberon
def: "An epithelium that is part of a uterus." [OBOL:automatic]
synonym: "uterus epithelium" RELATED [BTO:0003082]
xref: BTO:0003082
is_a: UBERON:0004804 ! oviduct epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000995 ! uterus
relationship: part_of UBERON:0000995 ! uterus

[Term]
id: UBERON:0006960
name: ovary stroma
namespace: uberon
def: "The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis." [Wikipedia:Stroma_of_ovary]
subset: human_reference_atlas
synonym: "interstitial tissue of ovary" EXACT [FMA:18626]
synonym: "ovarian stroma" EXACT [FMA:18626]
synonym: "ovary stroma" EXACT [MA:0002991]
synonym: "stroma of the ovary" EXACT [Wikipedia:Stroma_of_ovary]
synonym: "stroma ovarica" EXACT [FMA:18626]
synonym: "stroma ovarii" RELATED OMO:0003011 [Wikipedia:Stroma_of_ovary]
xref: CALOHA:TS-1246
xref: EMAPA:28880
xref: FMA:18626
xref: MA:0002991
xref: NCIT:C33638
xref: SCTID:259306002
xref: UMLS:C0737271 {source="ncithesaurus:Stroma_of_the_Ovarian_Cortex"}
xref: Wikipedia:Stroma_of_ovary
is_a: UBERON:0003891 ! stroma
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0003891 ! stroma
intersection_of: part_of UBERON:0000992 ! ovary
relationship: has_part CL:0002095 {source="FMA"} ! hilus cell of ovary
relationship: part_of UBERON:0000992 ! ovary
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0006965
name: vascular cord
namespace: uberon
def: "The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]." [GO:0072360, ZFA:0005077]
subset: efo_slim
xref: EFO:0003709
xref: TAO:0005077
xref: ZFA:0005077
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0005423 ! developing anatomical structure
relationship: has_part CL:0000115 ! endothelial cell
relationship: has_part CL:0000566 ! angioblastic mesenchymal cell
relationship: part_of UBERON:0014903 ! primordial vasculature
relationship: site_of GO:0048754 ! branching morphogenesis of an epithelial tube

[Term]
id: UBERON:0006966
name: coronary capillary
namespace: uberon
def: "A capillary that is part of the coronary system." [http://orcid.org/0000-0002-6601-2165]
synonym: "heart capillary" EXACT [GO:0003248]
xref: ZFA:0005813
is_a: UBERON:0001982 ! capillary
is_a: UBERON:0003498 ! heart blood vessel
intersection_of: UBERON:0001982 ! capillary
intersection_of: part_of UBERON:0000948 ! heart

[Term]
id: UBERON:0006984
name: anatomical surface
namespace: uberon
def: "A two dimensional anatomical structure that is the boundary between an anatomical structure and an anatomical substance, an anatomical space or the organism's environment. Examples include the surface of your skin, the surface of the lining of your gut; the surface of the endothelium of you aorta that is in contact with blood.n." [CARO:0001002]
comment: Old definition: 'Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures.' Note, in the new definition, the space referred to is not necessarily an anatomical space. It may be the outside of an organism.
subset: upper_level
xref: BILA:0000010
xref: CARO:0001002
xref: EHDAA2_RETIRED:0003192
xref: FMA:24137
xref: NCIT:C34022
xref: UMLS:C1515977 {source="ncithesaurus:Anatomic_Surface"}
is_a: UBERON:0010199 {notes="via morphological boundary in CARO"} ! bona-fide anatomical boundary

[Term]
id: UBERON:0007005
name: cardiogenic splanchnic mesoderm
namespace: uberon
def: "The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]." [http://www.drugs.com/dict/cardiogenic-mesoderm.html, https://github.com/obophenotype/insect_neuroanatomy_ontology/issues/7, XAO:0000235]
subset: efo_slim
subset: pheno_slim
synonym: "cardiac mesoderm" RELATED [XAO:0000235]
synonym: "cardiogenic mesoderm" RELATED [http://www.drugs.com/dict/cardiogenic-mesoderm.html]
synonym: "cardiogenic region" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "cardiogenic splanchnopleure" EXACT [EHDAA2:0000214]
synonym: "heart primordia" RELATED [XAO:0000235]
xref: AAO:0011021
xref: BILA:0000051
xref: EFO:0000315
xref: EHDAA2:0000214
xref: EHDAA:385
xref: FMA:293143
xref: SCTID:360387000
xref: VHOG:0001641
xref: XAO:0000235
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
relationship: developmentally_induced_by UBERON:0009881 ! anterior lateral plate mesoderm
relationship: develops_from UBERON:0004872 ! splanchnic layer of lateral plate mesoderm
relationship: part_of UBERON:0004140 ! primary heart field
relationship: part_of UBERON:0009881 ! anterior lateral plate mesoderm
property_value: editor_note "consider FBbt:00005541 ! cardiogenic mesoderm" xsd:string
property_value: editor_note "review EHDAA2 placement" xsd:string

[Term]
id: UBERON:0007010
name: cleaving embryo
namespace: uberon
def: "Organism at the cleavage stage." [OBOL:automatic]
xref: BILA:0000058
is_a: UBERON:0000922 ! embryo
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: existence_ends_with UBERON:0000107 ! cleavage stage
intersection_of: existence_starts_with UBERON:0000107 ! cleavage stage
relationship: existence_ends_with UBERON:0000107 ! cleavage stage
relationship: existence_starts_with UBERON:0000107 ! cleavage stage

[Term]
id: UBERON:0007021
name: sexually immature organism
namespace: uberon
def: "A multicellular organism that is at the juvenile stage." [OBOL:automatic]
synonym: "juvenile" BROAD []
synonym: "juvenile organism" EXACT [BILA:0000076]
synonym: "juveniles" EXACT OMO:0003004 [TAO:0002047]
xref: BILA:0000076
xref: http://neurolex.org/wiki/Category\:Juvenile_organism
xref: TAO:0002047
is_a: UBERON:0000468 ! multicellular organism
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: existence_ends_with UBERON:0000112 ! sexually immature stage
intersection_of: existence_starts_with UBERON:0000112 ! sexually immature stage
relationship: existence_ends_with UBERON:0000112 ! sexually immature stage
relationship: existence_starts_with UBERON:0000112 ! sexually immature stage
relationship: has_quality PATO:0001190 ! juvenile
property_value: UBPROP:0000001 "Whole organism that is not fully grown or sexually mature.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002047", ontology="TAO", source="TAO:wd"}

[Term]
id: UBERON:0007023
name: adult organism
namespace: uberon
def: "A multicellular organism that existence_ends_with a post-juvenile adult stage and existence_starts_with a post-juvenile adult stage." [OBOL:automatic]
synonym: "adult" BROAD []
synonym: "adults" EXACT OMO:0003004 [TAO:0002046]
xref: BILA:0000078
xref: FBbt:00003004 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: galen:Adult
xref: HAO:0000087
xref: http://neurolex.org/wiki/Category\:Adult_organism
xref: NCIT:C17600
xref: TAO:0002046
xref: UMLS:C0001675 {source="ncithesaurus:Adult"}
is_a: UBERON:0000468 ! multicellular organism
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: existence_ends_with UBERON:0000113 ! post-juvenile adult stage
intersection_of: existence_starts_with UBERON:0000113 ! post-juvenile adult stage
relationship: existence_ends_with UBERON:0000113 ! post-juvenile adult stage
relationship: existence_starts_with UBERON:0000113 ! post-juvenile adult stage
property_value: UBPROP:0000001 "Whole organism that is fully grown or sexually mature.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002046", ontology="TAO", source="TAO:wd"}

[Term]
id: UBERON:0007026
name: presumptive gut
namespace: uberon
synonym: "embryonic digestive tube" RELATED []
synonym: "future digestive tract" EXACT []
synonym: "future digestive tube" EXACT []
synonym: "future gut" EXACT []
synonym: "primitive gut" EXACT []
synonym: "primordial digestive tube" RELATED []
synonym: "primordial gut" RELATED []
xref: BILA:0000084
xref: NCIT:C34268
xref: SCTID:360394002
xref: UMLS:C1514442 {source="ncithesaurus:Primordial_Gut"}
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0001555 ! digestive tract
relationship: existence_starts_during UBERON:0000109 ! gastrula stage
relationship: has_developmental_contribution_from UBERON:0000925 ! endoderm
relationship: has_developmental_contribution_from UBERON:0000926 ! mesoderm
relationship: has_potential_to_develop_into UBERON:0001555 ! digestive tract
property_value: UBPROP:0000011 "The endodermal cells generate only the lining of the digestive tube and its glands; mesodermal mesenchyme cells will surround this tube to provide the muscles for peristalsis" xsd:string {source="NCBIBook:NBK10107"}

[Term]
id: UBERON:0007037
name: mechanosensory system
namespace: uberon
xref: BILA:0000142
is_a: UBERON:0001032 ! sensory system
intersection_of: UBERON:0001032 ! sensory system
intersection_of: capable_of GO:0050954 ! sensory perception of mechanical stimulus
relationship: capable_of GO:0050954 ! sensory perception of mechanical stimulus

[Term]
id: UBERON:0007095
name: somatic musculature
namespace: uberon
xref: BILA:0000133
is_a: UBERON:0000383 ! musculature of body

[Term]
id: UBERON:0007098
name: mandibular neural crest
namespace: uberon
def: "Cranial neural crest that migrates into the mandibular arch." [ZFA:0007064]
xref: TAO:0007064
xref: XAO:0000024
xref: ZFA:0007064
is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest
relationship: part_of UBERON:0003852 {source="ZFA"} ! rhombencephalon neural crest

[Term]
id: UBERON:0007100
name: primary circulatory organ
namespace: uberon
def: "A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]." [GO:0007507]
comment: Gene notes: Bmp, Nkx, Gata
subset: grouping_class
synonym: "adult heart" RELATED [FBbt:00003154]
synonym: "dorsal tube" NARROW [Wikipedia:Heart]
synonym: "heart" NARROW [GO:0007507]
xref: http://www.sciencemag.org/content/313/5795/1922/F1.large.jpg
xref: SPD:0000130
xref: TADS:0000147
is_a: UBERON:0015228 ! circulatory organ
intersection_of: UBERON:0015228 ! circulatory organ
intersection_of: capable_of GO:0008015 ! blood circulation
relationship: capable_of GO:0008015 {notes="GO uses blood circulation generically to include the haemolymphatic fluid of arthropods"} ! blood circulation
relationship: has_part CL:0002494 ! cardiocyte
property_value: UBPROP:0000008 "note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis" xsd:string

[Term]
id: UBERON:0007106
name: chorionic villus
namespace: uberon
def: "One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta." [BTO:0001161, Wikipedia:Chorionic_villi]
synonym: "chorionic villi" RELATED OMO:0003004 [MESH:A16.254.403.473.200]
synonym: "chorionic villous" RELATED [Wikipedia:Chorionic_villi]
synonym: "chorionic villus" RELATED [GAID:1300]
synonym: "embryonic part of placenta" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "embryonic placenta" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "fetal part of placenta" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "fetal placenta" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "placental villi" RELATED OMO:0003004 [GAID:1300]
synonym: "placental villous" RELATED []
synonym: "placental villus" RELATED [GAID:1300]
synonym: "villous chorion" RELATED []
synonym: "villous of placenta" RELATED []
xref: BTO:0001161
xref: EHDAA2:0004717
xref: MESH:D002824
xref: NCIT:C34125
xref: SCTID:360403003
xref: UMLS:C0008508 {source="ncithesaurus:Chorionic_Villus"}
xref: Wikipedia:Chorionic_villi
is_a: UBERON:0000478 ! extraembryonic structure
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0004027 {source="MP-def"} ! chorionic plate
relationship: part_of UBERON:0003124 {source="BTO"} ! chorion membrane
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/1e/Gray29.png" xsd:anyURI
property_value: UBPROP:0000008 "The mouse and human placentas have labyrinthine and villous types of interdigitation between maternal and fetal tissues, respectively" xsd:string
property_value: UBPROP:0000010 "The bulk of the villi consist of connective tissues in which blood vessels are found. Most of the cells in the connective tissue core of the villi are fibroblasts. Macrophages known as Hofbauer cells are also present." xsd:string

[Term]
id: UBERON:0007134
name: trunk ganglion
namespace: uberon
def: "Ganglion which is located in the trunk." [ZFIN:curator]
subset: efo_slim
synonym: "body ganglion" EXACT [MAT:0000344]
synonym: "trunk ganglia" EXACT OMO:0003004 [ZFA:0001573]
xref: EFO:0000901
xref: MAT:0000344
xref: MIAA:0000344
xref: TAO:0001573
xref: ZFA:0001573
is_a: UBERON:0000045 ! ganglion
intersection_of: UBERON:0000045 ! ganglion
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk

[Term]
id: UBERON:0007135
name: neural keel
namespace: uberon
def: "An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section." [ZFIN:ZDB-PUB-961014-576]
subset: efo_slim
synonym: "presumptive central nervous system" RELATED [ZFA:0000131]
xref: EFO:0003497
xref: TAO:0000131
xref: ZFA:0000131
is_a: UBERON:0016879 ! future central nervous system
relationship: develops_from UBERON:0003075 ! neural plate
property_value: UBPROP:0000001 "An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000131", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0007144
name: embryonic post-anal tail
namespace: uberon
def: "An embryonic structure that will either develop into a post-anal tail or recede into a vestigial remnant of the tail." [http://orcid.org/0000-0002-6601-2165]
synonym: "embryo tail" EXACT [FMA:85540]
synonym: "embryonic tail" RELATED [FMA:85540]
synonym: "tail of embryo" EXACT [FMA:85540]
xref: EMAPA:16748
xref: FMA:85540
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0002533 ! post-anal tail bud
relationship: transformation_of UBERON:0002533 ! post-anal tail bud
property_value: UBPROP:0000011 "By the fourth week a clear tail is seen in the human embryo. It recedes after a few weeks and these tissues form what is commonly known as the tailbone (coccyx)." xsd:string

[Term]
id: UBERON:0007147
name: lumen of midgut
namespace: uberon
def: "An anatomical cavity that surrounded_by a midgut." [OBOL:automatic]
synonym: "midgut lumen" EXACT [FMA:54366]
xref: EMAPA:18377
xref: FMA:54366
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0001045 ! midgut
relationship: luminal_space_of UBERON:0001045 ! midgut
relationship: part_of UBERON:0001045 ! midgut

[Term]
id: UBERON:0007148
name: lumen of hindgut
namespace: uberon
def: "An anatomical cavity that surrounded_by a hindgut." [OBOL:automatic]
synonym: "hindgut lumen" EXACT [FMA:54367]
xref: EMAPA:18396
xref: FMA:54367
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0001046 ! hindgut
relationship: luminal_space_of UBERON:0001046 ! hindgut
relationship: part_of UBERON:0001046 ! hindgut

[Term]
id: UBERON:0007158
name: lumen of anal canal
namespace: uberon
def: "An anatomical cavity that surrounded_by a anal canal." [OBOL:automatic]
synonym: "anal canal lumen" EXACT [FMA:17357]
xref: EMAPA:18836
xref: FMA:17357
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000159 ! anal canal
relationship: luminal_space_of UBERON:0000159 ! anal canal
relationship: part_of UBERON:0000159 ! anal canal

[Term]
id: UBERON:0007159
name: lumen of colon
namespace: uberon
def: "An anatomical cavity that surrounded_by a colon." [OBOL:automatic]
synonym: "colon lumen" EXACT [FMA:18374]
synonym: "colonic lumen" RELATED [FMA:18374]
xref: EMAPA:18945
xref: FMA:18374
xref: SCTID:362156004
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0001155 ! colon
relationship: luminal_space_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon

[Term]
id: UBERON:0007177
name: lamina propria of mucosa of colon
namespace: uberon
def: "A lamina propria that is part of a colonic mucosa." [OBOL:automatic]
subset: human_reference_atlas
synonym: "colonic lamina propria" EXACT [FMA:15657]
synonym: "lamina propria mucosae of colon" EXACT [FMA:15657]
synonym: "lamina propria of colonic mucosa" EXACT [FMA:15657]
synonym: "lamina propria of colonic mucous membrane" EXACT [FMA:15657]
xref: EMAPA:27395
xref: FMA:15657
xref: MA:0003196
xref: SCTID:113284008
is_a: UBERON:0011189 ! lamina propria of large intestine
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0000317 ! colonic mucosa
relationship: part_of UBERON:0000317 ! colonic mucosa
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0007181
name: serosa of infundibulum of uterine tube
namespace: uberon
def: "A serous membrane that is part of a uterine tube infundibulum." [OBOL:automatic]
synonym: "serosa of infundibulum of fallopian tube" EXACT [FMA:18324]
synonym: "serosa of infundibulum of oviduct" EXACT [FMA:18324]
xref: EMAPA:29903
xref: FMA:18324
is_a: UBERON:0000042 ! serous membrane
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0003984 ! uterine tube infundibulum
relationship: part_of UBERON:0003983 ! conus arteriosus
relationship: part_of UBERON:0003984 ! uterine tube infundibulum

[Term]
id: UBERON:0007182
name: muscle layer of infundibulum of uterine tube
namespace: uberon
def: "A muscle layer that is part of a uterine tube infundibulum." [OBOL:automatic]
synonym: "muscle layer of infundibulum of fallopian tube" EXACT [FMA:18336]
synonym: "muscle layer of infundibulum of oviduct" EXACT [FMA:18336]
synonym: "muscularis of infundibulum of uterine tube" EXACT [FMA:18336]
xref: EMAPA:31264
xref: FMA:18336
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0005983 ! heart layer
is_a: UBERON:0006660 ! muscular coat
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0003984 ! uterine tube infundibulum
relationship: part_of UBERON:0003983 ! conus arteriosus
relationship: part_of UBERON:0003984 ! uterine tube infundibulum

[Term]
id: UBERON:0007188
name: mesothelium of serous pericardium
namespace: uberon
def: "A mesothelium that is part of a serous pericardium." [OBOL:automatic]
synonym: "mesothelium of pericardium" EXACT [FMA:18149]
synonym: "pericardial mesothelium" EXACT [FMA:18149]
synonym: "serous pericardium mesothelium" EXACT [FMA:18149]
xref: BTO:0003157
xref: EMAPA:16133
xref: FMA:18149
xref: SCTID:67300002
is_a: UBERON:0003388 ! mesothelium of pericardial cavity
intersection_of: UBERON:0001136 ! mesothelium
intersection_of: part_of UBERON:0002357 ! serous pericardium
relationship: part_of UBERON:0002357 ! serous pericardium

[Term]
id: UBERON:0007195
name: stroma of bone marrow
namespace: uberon
def: "The stroma of the bone marrow is all tissue not directly involved in the primary function of hematopoiesis. The yellow bone marrow belongs here, and makes the majority of the bone marrow stroma, in addition to stromal cells located in the red bone marrow. Yellow bone marrow is found in the Medullary cavity. Still, the stroma is indirectly involved in hematopoiesis, since it provides the hematopoietic microenvironment that facilitates hematopoiesis by the parenchymal cells. For instance, they generate colony stimulating factors, affecting hematopoiesis." [Wikipedia:Bone_marrow#Stroma]
synonym: "bone marrow stroma" EXACT [FMA:21426]
xref: CALOHA:TS-0085
xref: FMA:21426
xref: Wikipedia:Bone_marrow#Stroma
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0003891 ! stroma
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0003891 ! stroma
intersection_of: part_of UBERON:0002371 ! bone marrow
relationship: has_part CL:0002240 ! marrow fibroblast
relationship: has_part UBERON:0000332 ! yellow bone marrow
relationship: has_part UBERON:0003909 ! sinusoid
relationship: part_of UBERON:0002371 ! bone marrow

[Term]
id: UBERON:0007197
name: hermaphroditic organism
namespace: uberon
def: "Multicellular organism that can produce both male and female gametes." [http://orcid.org/0000-0001-9114-8737]
synonym: "dioecious organism" RELATED [BILA:0000029]
synonym: "hermaphrodite" RELATED [WBbt:0007849]
xref: AAO:0010035
xref: BILA:0000029
xref: CARO:0000029
xref: HAO:0000029
xref: TADS:0000601
xref: WBbt:0007849
is_a: UBERON:0000468 ! multicellular organism

[Term]
id: UBERON:0007198
name: hermaphrodite anatomical structure
namespace: uberon
def: "An anatomical structure present only in hermaphrodites." [https://orcid.org/0000-0002-4422-9726]
synonym: "hermaphrodite-specific" RELATED [WBbt:0005758]
xref: AEO:0000177
xref: EHDAA2:0003177
xref: WBbt:0005758
is_a: UBERON:0014402 ! sex-specific anatomical structure
intersection_of: UBERON:0014402 ! sex-specific anatomical structure
intersection_of: part_of UBERON:0007197 ! hermaphroditic organism
relationship: part_of UBERON:0007197 ! hermaphroditic organism

[Term]
id: UBERON:0007204
name: brachiocephalic vasculature
namespace: uberon
def: "The vasculature consisting of brachiocephalic arteries and veins." [http://orcid.org/0000-0002-6601-2165]
is_a: UBERON:0002049 ! vasculature

[Term]
id: UBERON:0007213
name: mesenchyme derived from head neural crest
namespace: uberon
def: "Mesenchyme that develops_from a cranial neural crest." [OBOL:automatic]
subset: efo_slim
subset: vertebrate_core
synonym: "head mesenchyme from cranial neural crest" EXACT []
synonym: "head mesenchyme from neural crest" EXACT [EHDAA2:0000735]
synonym: "head neural crest derived mesenchyme" EXACT []
xref: EFO:0003572
xref: EHDAA2:0000735
xref: EMAPA:16169
xref: EMAPA:16271
xref: EMAPA_RETIRED:16271
xref: TAO:0000787
xref: ZFA:0000787
is_a: UBERON:0005253 {source="ZFA"} ! head mesenchyme
is_a: UBERON:0014387 ! mesenchyme derived from neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0003099 ! cranial neural crest
relationship: develops_from UBERON:0003099 ! cranial neural crest

[Term]
id: UBERON:0007214
name: mesenchyme derived from trunk neural crest
namespace: uberon
def: "Mesenchyme that develops_from a trunk neural crest." [OBOL:automatic]
subset: vertebrate_core
synonym: "trunk mesenchyme from neural crest" EXACT [EHDAA2:0002093]
synonym: "trunk neural crest derived mesenchyme" EXACT []
xref: EHDAA2:0002093
xref: EMAPA:16182
xref: TAO:0000999
xref: ZFA:0000999
is_a: UBERON:0005256 ! trunk mesenchyme
is_a: UBERON:0014387 ! mesenchyme derived from neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0003083 ! trunk neural crest
relationship: develops_from UBERON:0003083 ! trunk neural crest

[Term]
id: UBERON:0007220
name: late embryonic stage
namespace: uberon
def: "An embryo stage that covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching." [https://orcid.org/0000-0003-3308-6245]
synonym: "embryo late (growth) stage" EXACT [MIAA:0000399]
synonym: "embryo late growth stage" RELATED [BTO:0000449]
synonym: "embryo late stage" RELATED [BTO:0000449]
synonym: "fetal stage" NARROW SENSU [https://orcid.org/0000-0002-6601-2165]
synonym: "fetus" NARROW [MIAA:0000399]
synonym: "fetus stage" NARROW SENSU [https://orcid.org/0000-0002-6601-2165]
xref: EV:0300011
xref: EVM:2990031
xref: FBdv:00005333
xref: FMA:63631
xref: MIAA:0000399
xref: MmusDv:0000031
xref: OGES:000023
xref: SCTID:367619004
is_a: UBERON:0000105 ! life cycle stage
relationship: part_of UBERON:0000068 ! embryo stage
relationship: preceded_by UBERON:0000111 ! organogenesis stage
relationship: preceded_by UBERON:0004707 ! pharyngula stage
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/355" xsd:anyURI
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/565" xsd:anyURI

[Term]
id: UBERON:0007237
name: 1st arch mandibular component
namespace: uberon
synonym: "ventral mandibular arch" RELATED [VHOG:0000510]
synonym: "ventral pharyngeal arch 1" EXACT [VHOG:0000510]
synonym: "ventral visceral arch 1" RELATED [VHOG:0000510]
xref: EHDAA2:0000031
xref: EHDAA:583
xref: EMAPA:16382
xref: VHOG:0000510
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0004362 {source="EHDAA2"} ! pharyngeal arch 1
property_value: editor_note "relationship to Meckel's cartilage to be added" xsd:string
property_value: UBPROP:0000003 "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000510", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0007238
name: 1st arch maxillary component
namespace: uberon
xref: EHDAA2:0000038
xref: EHDAA:595
xref: EMAPA:16388
xref: VHOG:0000511
is_a: UBERON:0002050 ! embryonic structure
relationship: part_of UBERON:0004362 {source="EHDAA2"} ! pharyngeal arch 1
property_value: editor_note "relationship to palatoquadrate to be added" xsd:string
property_value: UBPROP:0000003 "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000511", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0007239
name: tunica media of artery
namespace: uberon
def: "A tunica media that is part of a artery." [OBOL:automatic]
synonym: "arterial media" EXACT [EV:0100029]
synonym: "tunica media (arteriae)" EXACT [FMA:14273]
xref: EMAPA:36294
xref: EV:0100029
xref: FMA:14273
xref: NCIT:C49321
xref: SCTID:84300001
xref: UMLS:C1710627 {source="ncithesaurus:Venous_System_Smooth_Muscle_Tissue"}
is_a: UBERON:0002522 ! tunica media
intersection_of: UBERON:0002522 ! tunica media
intersection_of: part_of UBERON:0001637 ! artery
relationship: part_of UBERON:0000415 ! artery wall

[Term]
id: UBERON:0007240
name: tunica adventitia of artery
namespace: uberon
def: "A tunica adventitia that is part of a artery." [OBOL:automatic]
synonym: "arterial adventitia" EXACT [EV:0100030]
synonym: "tunica externa (adventitia)(arteriae)" EXACT [FMA:14274]
xref: EMAPA:36295
xref: EV:0100030
xref: FMA:14274
xref: SCTID:113261001
is_a: UBERON:0005734 ! tunica adventitia of blood vessel
intersection_of: UBERON:0005734 ! tunica adventitia of blood vessel
intersection_of: part_of UBERON:0001637 ! artery
relationship: has_part CL:1000306 {source="FMA"} ! fibroblast of tunica adventitia of artery
relationship: part_of UBERON:0000415 ! artery wall

[Term]
id: UBERON:0007241
name: tunica adventitia of vein
namespace: uberon
def: "A tunica adventitia that is part of a vein." [OBOL:automatic]
synonym: "tunica externa (adventitia)(venae)" EXACT [FMA:14355]
synonym: "venous adventitia" EXACT [EV:0100034]
xref: EMAPA:36310
xref: EV:0100034
xref: FMA:14355
xref: SCTID:13202006
is_a: UBERON:0005734 ! tunica adventitia of blood vessel
intersection_of: UBERON:0005734 ! tunica adventitia of blood vessel
intersection_of: part_of UBERON:0001638 ! vein
relationship: part_of UBERON:0001638 ! vein

[Term]
id: UBERON:0007242
name: tunica intima of vein
namespace: uberon
def: "A tunica intima that is part of a vein." [OBOL:automatic]
synonym: "tunica interna (intima)(venae)" EXACT [FMA:14353]
synonym: "venous intima" EXACT [EV:0100032]
xref: EMAPA:36308
xref: EV:0100032
xref: FMA:14353
xref: SCTID:2436009
is_a: UBERON:0002523 ! tunica intima
is_a: UBERON:0004797 ! blood vessel layer
intersection_of: UBERON:0002523 ! tunica intima
intersection_of: part_of UBERON:0001638 ! vein
relationship: part_of UBERON:0001638 ! vein

[Term]
id: UBERON:0007243
name: tunica media of vein
namespace: uberon
def: "A tunica media that is part of a vein." [OBOL:automatic]
synonym: "tunica media (venae)" EXACT [FMA:14354]
synonym: "venous media" EXACT [EV:0100033]
xref: EMAPA:36309
xref: EV:0100033
xref: FMA:14354
xref: SCTID:42049001
is_a: UBERON:0002522 ! tunica media
intersection_of: UBERON:0002522 ! tunica media
intersection_of: part_of UBERON:0001638 ! vein
relationship: part_of UBERON:0001638 ! vein

[Term]
id: UBERON:0007245
name: nuclear complex of neuraxis
namespace: uberon
def: "Gray matter of the central nervous system which is a collection of clustered nuclei." [http://orcid.org/0000-0002-6601-2165]
synonym: "cluster of neural nuclei" RELATED []
synonym: "neural nuclei" RELATED []
synonym: "nuclear complex" RELATED []
xref: FMA:256381
xref: FMA:84059
is_a: UBERON:0002020 ! gray matter
intersection_of: UBERON:0002020 ! gray matter
intersection_of: composed_primarily_of UBERON:0000125 ! neural nucleus
relationship: composed_primarily_of UBERON:0000125 ! neural nucleus

[Term]
id: UBERON:0007247
name: nucleus of superior olivary complex
namespace: uberon
def: "Any of the nuclei that comprise the superior olivary complex (superior olive). This includes both the primary nuclei such as the lateral and medial nuclei, as well as periolivary nuclei." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
subset: pheno_slim
synonym: "superior olivary complex nucleus" EXACT [FMA:72246]
xref: FMA:72246
xref: SCTID:369024009
is_a: UBERON:0006331 ! brainstem nucleus
is_a: UBERON:0009662 ! hindbrain nucleus
intersection_of: UBERON:0002308 ! nucleus of brain
intersection_of: part_of UBERON:0002128 ! superior olivary complex
relationship: part_of UBERON:0002128 ! superior olivary complex
property_value: curator_notes "this class exists largely for consistency with the FMA. It is defined trivially with respect to the SOC. The class may be removed in future." xsd:string

[Term]
id: UBERON:0007269
name: pectoral appendage musculature
namespace: uberon
def: "Any collection of muscles that is part of a pectoral appendage." [OBOL:automatic]
subset: efo_slim
synonym: "pectoral fin muscle" NARROW [ZFA:0000563]
synonym: "pectoral fin musculature" NARROW SENSU [ZFA:0000563]
xref: EFO:0003540
xref: TAO:0000563
xref: ZFA:0000563
is_a: UBERON:0007271 ! appendage musculature
is_a: UBERON:0014793 ! musculature of pectoral complex
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0004710 ! pectoral appendage
relationship: part_of UBERON:0004710 ! pectoral appendage
property_value: editor_note "currently defined by location rather than attachment" xsd:string

[Term]
id: UBERON:0007270
name: pelvic appendage musculature
namespace: uberon
def: "Any collection of muscles that is part of a pelvic appendage." [OBOL:automatic]
synonym: "pelvic fin musculature" NARROW SENSU [ZFA:0000258]
xref: TAO:0000258
xref: ZFA:0000258
is_a: UBERON:0007271 ! appendage musculature
is_a: UBERON:0014792 ! musculature of pelvic complex
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0004709 ! pelvic appendage
relationship: part_of UBERON:0004709 ! pelvic appendage
property_value: editor_note "currently defined by location rather than attachment" xsd:string
property_value: UBPROP:0000001 "Musculature that is part of the pelvic fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000258", ontology="TAO", source="TAO:curator"}

[Term]
id: UBERON:0007271
name: appendage musculature
namespace: uberon
def: "Any collection of muscles that is part of an appendage." [OBOL:automatic]
synonym: "fin musculature" NARROW SENSU [ZFA:0000207]
xref: TAO:0000207
xref: ZFA:0000207
is_a: UBERON:0001015 ! musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0000026 ! appendage
relationship: part_of UBERON:0000026 ! appendage
property_value: editor_note "currently defined by location rather than attachment" xsd:string

[Term]
id: UBERON:0007272
name: pectoral appendage skeleton
namespace: uberon
def: "Skeletal subdivision consisting of the anterior appendicular limb skeleton, excluding the pectoral girdle." [VSAO:0005000, VSAO:NI]
synonym: "cheiropterygium" RELATED [VSAO:0005000, VSAO:NI]
xref: VSAO:0005000
is_a: UBERON:0011582 ! paired limb/fin skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: skeleton_of UBERON:0004710 ! pectoral appendage
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0004710 {source="VSAO"} ! pectoral appendage
relationship: skeleton_of UBERON:0004710 ! pectoral appendage
property_value: RO:0002475 UBERON:0007273

[Term]
id: UBERON:0007273
name: pelvic appendage skeleton
namespace: uberon
def: "The collection of all skeletal elements in a pelvic appendage region." [https://orcid.org/0000-0002-6601-2165]
is_a: UBERON:0011582 ! paired limb/fin skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: skeleton_of UBERON:0004709 ! pelvic appendage
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0004709 {source="VSAO"} ! pelvic appendage
relationship: skeleton_of UBERON:0004709 ! pelvic appendage

[Term]
id: UBERON:0007277
name: presumptive hindbrain
namespace: uberon
def: "The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure." [Wikipedia:Rhombencephalon]
subset: efo_slim
synonym: "embryonic rhombencephalon" RELATED [CALOHA:TS-2118]
synonym: "future hindbrain" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "presumptive rhombencephalon" EXACT [ZFA:0000569]
synonym: "rhombencephalon" RELATED [EHDAA2:0001630]
xref: BAMS:HB
xref: CALOHA:TS-2118
xref: EFO:0003440
xref: EHDAA2:0001630
xref: FMA:295640
xref: TAO:0000569
xref: Wikipedia:Rhombencephalon
xref: ZFA:0000569
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0002028 ! hindbrain
relationship: develops_from UBERON:0003076 {source="XAO-abduced"} ! posterior neural tube
relationship: has_developmental_contribution_from UBERON:0003852 {source="cjm"} ! rhombencephalon neural crest
relationship: has_potential_to_develop_into UBERON:0002028 ! hindbrain
relationship: part_of UBERON:0006238 ! future brain
property_value: editor_note "TODO - unify naming conventions" xsd:string
property_value: UBPROP:0000001 "The embryonic rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. Rhombomeres Rh7-Rh4 form the myelencephalon that will give the medulla oblongata. Rhombomeres Rh3-Rh1 form the metencephalon that will form the pons and the cerebellum[NPX:PDR]." xsd:string {source="NPX:PDR"}

[Term]
id: UBERON:0007278
name: presumptive sinus venosus
namespace: uberon
def: "Portion of tissue that is part of the heart tube and will become the sinus venosus." [ZFA:0001722]
xref: TAO:0002234
xref: ZFA:0001722
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0002063 ! sinus venosus
relationship: has_potential_to_develop_into UBERON:0002063 ! sinus venosus
relationship: part_of UBERON:0004141 {source="ZFA"} ! heart tube

[Term]
id: UBERON:0007280
name: presumptive endocardium
namespace: uberon
def: "A presumptive structure that has the potential to develop into a endocardium." [OBOL:automatic]
xref: TAO:0002233
xref: ZFA:0001724
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0002165 ! endocardium
relationship: develops_from UBERON:0003084 ! heart primordium
relationship: has_potential_to_develop_into UBERON:0002165 ! endocardium
relationship: part_of UBERON:0005498 ! primitive heart tube
property_value: UBPROP:0000001 "Portion of tissue that is part of the heart tube and will become the endocardium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002233", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0007281
name: presumptive midbrain hindbrain boundary
namespace: uberon
def: "Embryonic structure that gives rise to the midbrain hindbrain boundary." [ZFA:0001187]
subset: efo_slim
synonym: "presumptive MHB" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "presumptive midbrain-hindbrain boundary" EXACT [ZFA:0001187]
xref: EFO:0003446
xref: TAO:0001187
xref: XAO:0004086
xref: ZFA:0001187
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0003052 ! midbrain-hindbrain boundary
relationship: has_potential_to_develop_into UBERON:0003052 ! midbrain-hindbrain boundary
relationship: part_of UBERON:0006238 {source="ZFA"} ! future brain

[Term]
id: UBERON:0007282
name: presumptive segmental plate
namespace: uberon
def: "A presumptive structure that has the potential to develop into a presomitic mesoderm." [OBOL:automatic]
subset: efo_slim
synonym: "presumptive segmental plates" RELATED OMO:0003004 [ZFA:0000053]
xref: EFO:0003421
xref: TAO:0000053
xref: ZFA:0000053
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0003059 ! presomitic mesoderm
relationship: develops_from UBERON:0009618 {consistent_with="https://github.com/obophenotype/uberon/wiki/The-neural-crest", source="EDHAA2"} ! trunk paraxial mesoderm
relationship: has_potential_to_develop_into UBERON:0003059 ! presomitic mesoderm

[Term]
id: UBERON:0007284
name: presumptive neural plate
namespace: uberon
def: "A presumptive structure that has the potential to develop into a neural plate." [OBOL:automatic]
subset: efo_slim
synonym: "prospective neuroectoderm" EXACT [ZFA:0000063]
synonym: "prospective vegetal ectoderm" EXACT [ZFA:0000063]
xref: EFO:0003424
xref: TAO:0000063
xref: ZFA:0000063
is_a: UBERON:0016879 ! future central nervous system
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0003075 ! neural plate
relationship: develops_from UBERON:0002346 ! neurectoderm
relationship: has_potential_to_develop_into UBERON:0003075 ! neural plate
relationship: part_of UBERON:0004734 ! gastrula
property_value: editor_note "consider merging" xsd:string
property_value: UBPROP:0000001 "Region of the gastrula which gives rise to the neural plate.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000063", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0007285
name: presumptive paraxial mesoderm
namespace: uberon
def: "The part of the blastula that has the potential to develop into a paraxial mesoderm." [https://github.com/obophenotype/uberon/issues/1277, UBERON:cjm]
subset: efo_slim
synonym: "future paraxial mesenchyme" EXACT [UBERON:cjm]
synonym: "future paraxial mesoderm" EXACT []
xref: EFO:0003443
xref: TAO:0000591
xref: XAO:0004134
xref: ZFA:0000591
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 {source="https://github.com/obophenotype/uberon/issues/1277"} ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0003077 {source="https://github.com/obophenotype/uberon/issues/1277"} ! paraxial mesoderm
intersection_of: part_of UBERON:0000307 {source="https://github.com/obophenotype/uberon/issues/1277"} ! blastula
relationship: has_potential_to_develop_into UBERON:0003077 ! paraxial mesoderm
relationship: part_of UBERON:0000307 ! blastula

[Term]
id: UBERON:0007297
name: presumptive pronephric mesoderm
namespace: uberon
def: "A presumptive structure that has the potential to develop into a pronephric mesoderm." [OBOL:automatic]
subset: efo_slim
synonym: "nephron primordium" EXACT [ZFA:0001070]
xref: EFO:0003619
xref: TAO:0001070
xref: ZFA:0001070
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0005721 ! pronephric mesoderm
relationship: has_potential_to_develop_into UBERON:0005721 ! pronephric mesoderm

[Term]
id: UBERON:0007300
name: pectoral appendage blood vessel
namespace: uberon
def: "A blood vessel that is part of a pectoral appendage." [OBOL:automatic]
synonym: "pectoral fin blood vessel" NARROW SENSU [ZFA:0005301]
xref: TAO:0005301
xref: ZFA:0005301
is_a: UBERON:0007301 ! appendage blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0004710 ! pectoral appendage
relationship: part_of UBERON:0004710 ! pectoral appendage

[Term]
id: UBERON:0007301
name: appendage blood vessel
namespace: uberon
def: "A blood vessel that is part of a limb/fin." [OBOL:automatic]
synonym: "fin blood vessel" NARROW SENSU [ZFA:0005299]
synonym: "limb blood vessel" NARROW SENSU []
xref: TAO:0005299
xref: ZFA:0005299
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0000026 ! appendage
relationship: part_of UBERON:0007304 ! appendage vasculature

[Term]
id: UBERON:0007302
name: pectoral appendage vasculature
namespace: uberon
def: "A vasculature that is part of a pectoral appendage." [OBOL:automatic]
synonym: "pectoral fin vasculature" NARROW SENSU [ZFA:0005096]
xref: TAO:0005096
xref: ZFA:0005096
is_a: UBERON:0007304 ! appendage vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0004710 ! pectoral appendage
relationship: part_of UBERON:0004710 ! pectoral appendage

[Term]
id: UBERON:0007303
name: pharyngeal vasculature
namespace: uberon
def: "A vasculature that is part of a chordate pharynx." [OBOL:automatic]
synonym: "branchial vasculature" EXACT [ZFA:0005003]
xref: TAO:0005003
xref: ZFA:0005003
is_a: UBERON:0006876 ! vasculature of organ
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0001042 ! chordate pharynx
relationship: part_of UBERON:0001042 ! chordate pharynx

[Term]
id: UBERON:0007304
name: appendage vasculature
namespace: uberon
def: "A vasculature that is part of a limb/fin." [OBOL:automatic]
synonym: "fin vasculature" NARROW SENSU [ZFA:0005095]
xref: TAO:0005095
xref: ZFA:0005095
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0000026 ! appendage
relationship: part_of UBERON:0000026 ! appendage

[Term]
id: UBERON:0007324
name: pancreatic lobule
namespace: uberon
def: "A dense accumulation of exocrine glands in the pancreas often surrounding islets of Langerhans." [ISBN:0123813611]
subset: human_reference_atlas
synonym: "lobulus pancreaticus" EXACT [FMA:16012]
synonym: "pancreas lobe" EXACT [MA:0000721]
synonym: "pancreatic lobule" EXACT [FMA:16012]
xref: EMAPA:37710 {source="MA:th"}
xref: FMA:16012
xref: MA:0000721
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000064 ! organ part
is_a: UBERON:0004119 ! endoderm-derived structure
relationship: has_part UBERON:0001263 ! pancreatic acinus
relationship: has_part UBERON:0014719 ! intralobular duct
relationship: part_of UBERON:0000017 ! exocrine pancreas
property_value: editor_note "TODO - check" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "In mice many lobules lack islets, in contrast to other mammals including humans" xsd:string

[Term]
id: UBERON:0007329
name: pancreatic duct
namespace: uberon
def: "A duct that collects and carries secretions of the exocrine pancreas to the intestine." [GOC:cvs, GOC:ymb, https://github.com/obophenotype/uberon/issues/1250, https://orcid.org/0000-0002-2244-7917, https://orcid.org/0000-0002-6601-2165, https://orcid.org/0000-0002-9900-7880, Wikipedia:Pancreatic_duct]
subset: human_reference_atlas
subset: pheno_slim
subset: vertebrate_core
synonym: "duct of pancreas" EXACT [OBOL:accepted]
synonym: "ductus pancreaticus" RELATED OMO:0003011 [Wikipedia:Pancreatic_duct]
synonym: "pancreas duct" EXACT [OBOL:accepted]
xref: EHDAA:9194
xref: EMAPA:32952
xref: FMA:10419
xref: MA:0000124
xref: MESH:D010183 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: SCTID:181278006
xref: TAO:0001372
xref: VHOG:0000254
xref: Wikipedia:Pancreatic_duct
xref: ZFA:0001372
is_a: UBERON:0003928 {source="ZFA"} ! digestive system duct
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000058 ! duct
intersection_of: connected_to UBERON:0000160 ! intestine
intersection_of: part_of UBERON:0001264 ! pancreas
relationship: connected_to UBERON:0000160 ! intestine
relationship: contributes_to_morphology_of UBERON:0000017 ! exocrine pancreas
relationship: develops_from UBERON:0003922 ! pancreatic epithelial bud
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0000017 {source="MA"} ! exocrine pancreas
property_value: curator_notes "this class groups together accessory (dorsal) and main (ventral) pancreatic ducts" xsd:string
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Duct connecting the pancreas with the intestine. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000254", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "These data show that ducts within the zebrafish pancreas originally arise in situ from isolated progenitor cells rather than arising from reiterative branching of the pancreatic epithelium. This process of pancreatic duct formation in zebrafish may be analogous to the mechanism of duct formation in the mammalian mammary and salivary glands. (...) A related mechanism of duct formation has also been proposed to occur within the mammalian pancreatic epithelium.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000254", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.04.035 Yee NS, Lorent K, Pack M, Exocrine pancreas development in zebrafish. Developmental Biology (2005)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "in EHDAA2, the dorsal and ventral ducts are classified as epithelial sacs - review after overhaul of duct/epithelia terms" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0007375
name: roof of mouth
namespace: uberon
def: "A multi-tissue structure consisting of bone and soft tissue that forms a part of the roof of the oral cavity. In mammals this is the combination of the primary palate (premaxilla) and the secondary palate. In early tetrapods it consists of the vomer, pterygoid, parasphenoid, palatine and ectopterygoid bones." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "palate" RELATED []
synonym: "palatum" RELATED INCONSISTENT []
synonym: "primary or secondary palate" RELATED []
synonym: "roof of buccal cavity" EXACT []
synonym: "roof of oral cavity" EXACT []
xref: CALOHA:TS-2212
xref: Wikipedia:Palate
is_a: UBERON:0000481 ! multi-tissue structure
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0000033 ! head
property_value: editor_note "check subclasses to verify if they refer to a multi-tissue structure or a subdivision of the skeleton" xsd:string

[Term]
id: UBERON:0007376
name: outer epithelium
namespace: uberon
def: "The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]." [GO:0008544]
subset: grouping_class
synonym: "epidermis" EXACT [GO:0008544]
synonym: "epidermis (sensu Metazoa)" EXACT []
synonym: "hypoderm" RELATED INCONSISTENT [BTO:0000313]
synonym: "hypodermis" RELATED INCONSISTENT [GO:0008544, WBbt:0005733]
synonym: "outer epidermal layer" EXACT []
synonym: "outer epithelial layer" EXACT []
xref: BSA:0000073
xref: BTO:0000313
xref: FBbt:00004993 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: HAO:0000298
xref: TADS:0000109
xref: WBbt:0005733
xref: Wikipedia:Epidermis_(zoology)
is_a: UBERON:0003102 ! surface structure
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: bounding_layer_of UBERON:0000468 ! multicellular organism
intersection_of: develops_from UBERON:0007383 ! enveloping layer of ectoderm
relationship: bounding_layer_of UBERON:0000468 ! multicellular organism
relationship: develops_from UBERON:0007383 ! enveloping layer of ectoderm
relationship: only_in_taxon NCBITaxon:6072 {source="Wikipedia:Epidermis_(zoology)"} ! Eumetazoa
property_value: editor_note "this grouping class exists primarily to align with GO - see GO:0008544." xsd:string

[Term]
id: UBERON:0007383
name: enveloping layer of ectoderm
namespace: uberon
def: "Outermost layer of cells surrounding the embryo." [http://orcid.org/0000-0002-6601-2165]
subset: efo_slim
synonym: "enveloping layer" EXACT [ZFIN:ZDB-PUB-961014-576]
synonym: "EVL" EXACT [ZFA:0000086]
xref: EFO:0003425
xref: TAO:0000086
xref: ZFA:0000086
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
relationship: bounding_layer_of UBERON:0000922 ! embryo
relationship: develops_from UBERON:0000076 ! external ectoderm
property_value: UBPROP:0000001 "Outermost monolayer of cells surrounding the embryo that become very flattened in the blastula and give rise to the periderm. Sometimes used synonymously with periderm. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000086", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000002 "relationship loss: develops_from superficial blastomere (TAO:0001484)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000086", ontology="TAO"}
property_value: UBPROP:0000008 "Originally this tissue is one cell layer thick but in most vertebrates it soon becomes a two layered structure. The outer layer gives rise to the periderm." xsd:string

[Term]
id: UBERON:0007389
name: paired limb/fin cartilage
namespace: uberon
def: "A cartilage tissue that is part of a paired limb or fin." [http://orcid.org/0000-0002-6601-2165]
subset: homology_grouping
xref: TAO:0001543
xref: ZFA:0001543
is_a: UBERON:0002418 ! cartilage tissue
intersection_of: UBERON:0002418 ! cartilage tissue
intersection_of: part_of UBERON:0004708 ! paired limb/fin
relationship: part_of UBERON:0002091 ! appendicular skeleton
relationship: part_of UBERON:0004708 ! paired limb/fin
property_value: UBPROP:0000001 "Cartilage which is part of one of the paired fins.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001543", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0007390
name: pectoral appendage cartilage tissue
namespace: uberon
def: "A cartilage tissue that is part of a pectoral appendage." [OBOL:automatic]
synonym: "pectoral fin cartilage" RELATED [TAO:0000257]
xref: TAO:0000257
xref: ZFA:0000257
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0007389 ! paired limb/fin cartilage
intersection_of: UBERON:0002418 ! cartilage tissue
intersection_of: part_of UBERON:0004710 ! pectoral appendage
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0007272 ! pectoral appendage skeleton
property_value: UBPROP:0000001 "Cartilage which is part of the pectoral fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000257", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0007391
name: pelvic appendage cartilage tissue
namespace: uberon
def: "A cartilage tissue that is part of a pelvic appendage." [OBOL:automatic]
synonym: "pelvic fin cartilage" RELATED [TAO:0001459]
xref: TAO:0001459
xref: ZFA:0001459
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0007389 ! paired limb/fin cartilage
intersection_of: UBERON:0002418 ! cartilage tissue
intersection_of: part_of UBERON:0004709 ! pelvic appendage
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0007273 ! pelvic appendage skeleton
property_value: UBPROP:0000001 "Cartilage which is part of the pelvic fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001459", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0007414
name: nucleus of midbrain tegmentum
namespace: uberon
alt_id: UBERON:0012277
def: "A nucleus of brain that spans a midbrain tegmentum." [OBOL:automatic]
synonym: "tegmental nuclei" EXACT OMO:0003004 []
synonym: "tegmental nucleus" EXACT [ZFA:0005577]
xref: FMA:258768
xref: ZFA:0005577
is_a: UBERON:0000125 ! neural nucleus
intersection_of: UBERON:0000125 ! neural nucleus
intersection_of: overlaps UBERON:0001943 ! midbrain tegmentum
relationship: overlaps UBERON:0001943 ! midbrain tegmentum
property_value: curator_notes "this class groups together any nuclei in the tegmentum region, possibly including disparate structures across species" xsd:string

[Term]
id: UBERON:0007473
name: lumen of epithelial sac
namespace: uberon
def: "The space within an epithelial sphere." [AEO:JB]
synonym: "cavity of vesicle" EXACT [AEO:0000079]
xref: AEO:0000079
is_a: UBERON:0012467 ! enclosed anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0007499 ! epithelial sac
relationship: luminal_space_of UBERON:0007499 ! epithelial sac
relationship: part_of UBERON:0007499 ! epithelial sac

[Term]
id: UBERON:0007475
name: matrix-based tissue
namespace: uberon
def: "A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified." [AEO:JB]
xref: AEO:0000081
xref: EHDAA2:0003081
is_a: UBERON:0000479 ! tissue
intersection_of: UBERON:0000479 ! tissue
intersection_of: composed_primarily_of GO:0031012 ! extracellular matrix
relationship: composed_primarily_of GO:0031012 ! extracellular matrix

[Term]
id: UBERON:0007491
name: chitin-based acellular structure
namespace: uberon
def: "Acellular anatomical structure whose predominant constituent is chitin." [AEO:JB]
xref: AEO:0000100
xref: EHDAA2:0003100
is_a: UBERON:0000476 ! acellular anatomical structure
intersection_of: UBERON:0000476 ! acellular anatomical structure
intersection_of: composed_primarily_of CHEBI:17029 ! chitin
relationship: composed_primarily_of CHEBI:17029 ! chitin

[Term]
id: UBERON:0007499
name: epithelial sac
namespace: uberon
def: "An epithelial tube that is open at one end only." [AEO:JB, UBERONREF:0000001]
xref: AEO:0000115
xref: EHDAA2:0003115
is_a: UBERON:0003914 {source="AEO"} ! epithelial tube
is_a: UBERON:0009856 ! sac
intersection_of: UBERON:0000483 ! epithelium
intersection_of: has_quality PATO:0001987 ! saccular

[Term]
id: UBERON:0007500
name: epithelial tube open at both ends
namespace: uberon
def: "An epithelial tube open at both ends that allows fluid flow." [AEO:JB, UBERONREF:0000001]
xref: AEO_RETIRED:0000116
xref: RETIRED_EHDAA2:0003116
is_a: UBERON:0003914 {source="AEO"} ! epithelial tube

[Term]
id: UBERON:0007501
name: arborizing epithelial duct system
namespace: uberon
def: "A collection of connected epithelial tubes with a single portal." [AEO:JB, UBERONREF:0000001]
synonym: "arborising epithelial duct system" EXACT [AEO:0000117]
xref: AEO:0000117
xref: EHDAA2:0003117
is_a: UBERON:0007499 {source="AEO"} ! epithelial sac
relationship: has_part UBERON:0003914 {source="AEO"} ! epithelial tube

[Term]
id: UBERON:0007503
name: epithelial vesicle
namespace: uberon
def: "A closed epithelium with a lumen." [AEO:JB]
xref: AEO:0000119
xref: EHDAA2:0003119
is_a: UBERON:0000483 {source="AEO"} ! epithelium

[Term]
id: UBERON:0007521
name: smooth muscle sphincter
namespace: uberon
def: "A ring of smooth muscle cells whose contraction closes the opening of the ring." [AEO:JB]
xref: AEO:0000143
xref: EHDAA2:0003143
xref: SCTID:362915001
is_a: UBERON:0004590 ! sphincter muscle
intersection_of: UBERON:0004590 ! sphincter muscle
intersection_of: has_part CL:0000192 ! smooth muscle cell
relationship: composed_primarily_of UBERON:0001135 ! smooth muscle tissue
relationship: has_part CL:0000192 ! smooth muscle cell

[Term]
id: UBERON:0007522
name: striated muscle sphincter
namespace: uberon
def: "A ring of striated muscle cells whose contraction closes the opening of the ring." [AEO:JB]
xref: AEO:0000144
xref: EHDAA2:0003144
is_a: UBERON:0004590 ! sphincter muscle
intersection_of: UBERON:0004590 ! sphincter muscle
intersection_of: has_part CL:0000737 ! striated muscle cell
relationship: composed_primarily_of UBERON:0002036 ! striated muscle tissue
relationship: has_part CL:0000737 ! striated muscle cell

[Term]
id: UBERON:0007524
name: dense mesenchyme tissue
namespace: uberon
def: "Mesenchyme with little extracellular matrix." [AEO:JB]
xref: AEO:0000146
xref: EHDAA2:0003146
is_a: UBERON:0003104 {source="AEO"} ! mesenchyme
relationship: has_part CL:0000057 {source="AEO"} ! fibroblast

[Term]
id: UBERON:0007530
name: migrating mesenchyme population
namespace: uberon
def: "Mesenchymal cells that are migrating." [AEO:JB]
xref: AEO:0000152
xref: EHDAA2:0003152
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: participates_in GO:0016477 ! cell migration
relationship: participates_in GO:0016477 ! cell migration
property_value: editor_note "this class will be an important part of the NC reorganization" xsd:string

[Term]
id: UBERON:0007589
name: ciliated columnar oviduct epithelium
namespace: uberon
def: "A ciliated columnar epithelium that is part of a oviduct." [OBOL:automatic]
subset: human_reference_atlas
synonym: "epithelium of uterine tube" RELATED [FMA:62016]
synonym: "uterine tube epithelium" RELATED [FMA:62016]
xref: FMA:62016
xref: MA:0001719
is_a: UBERON:0004804 {source="MA"} ! oviduct epithelium
is_a: UBERON:0007592 {source="FMA"} ! ciliated columnar epithelium
intersection_of: UBERON:0007592 ! ciliated columnar epithelium
intersection_of: part_of UBERON:0000993 ! oviduct
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "in FMA, epithelium of uterine tube is a subclass of ciliated columnar epithelium. MA introduces subtypes: ciliated columnar and cuboidal. We map the FMA type according to its relationships, not its label" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0007590
name: cuboidal oviduct epithelium
namespace: uberon
def: "A cuboidal epithelium that is part of a oviduct." [OBOL:automatic]
subset: human_reference_atlas
xref: MA:0001720
is_a: UBERON:0004804 {source="MA"} ! oviduct epithelium
is_a: UBERON:0010077 ! cuboidal epithelium
intersection_of: UBERON:0010077 ! cuboidal epithelium
intersection_of: part_of UBERON:0000993 ! oviduct
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0007592
name: ciliated columnar epithelium
namespace: uberon
def: "Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA]." [FMA:64798]
xref: FMA:64798
is_a: UBERON:0000485 {source="FMA"} ! simple columnar epithelium
is_a: UBERON:0007601 ! ciliated epithelium
intersection_of: UBERON:0000485 ! simple columnar epithelium
intersection_of: has_part CL:0000067 ! ciliated epithelial cell
property_value: UBPROP:0000008 "In humans, Ciliated columnar epithelial cells are found mainly in the tracheal and bronchial regions of the pulmonary system and also in the fallopian tubes of the female reproductive system" xsd:string
property_value: UBPROP:0000009 "Ciliated columnar epithelium in the pulmonary system is interspersed with goblet cells that secrete mucous to form a mucosal layer apical to the epithelial layer. The rowing-like action of epithelial cilia work in tandem with goblet cells to propel mucus away from the lungs, preventing particulate matter from causing infection[http://www.bio.davidson.edu/people/kabernd/berndcv/lab/epithelialinfoweb/ciliated%20columnar%20epithelium.html]" xsd:string

[Term]
id: UBERON:0007601
name: ciliated epithelium
namespace: uberon
def: "Epithelium bearing vibratile cilia on the free surface." [http://medical-dictionary.thefreedictionary.com/ciliated+epithelium]
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: has_part CL:0000067 ! ciliated epithelial cell
relationship: has_part CL:0000067 ! ciliated epithelial cell

[Term]
id: UBERON:0007616
name: layer of synovial tissue
namespace: uberon
def: "A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]." [BTO:0001338, http://www.britannica.com/EBchecked/topic/578563/synovial-tissue]
synonym: "stratum synoviale" NARROW [FMA:TA]
synonym: "synovial layer" NARROW [FMA:66762]
synonym: "synovial membrane" NARROW [FMA:66762]
synonym: "synovial tissue" RELATED [BTO:0001338]
synonym: "synovium" EXACT [CALOHA:TS-0998]
xref: BTO:0001338
xref: CALOHA:TS-0998
xref: FMA:66762
is_a: UBERON:0000042 ! serous membrane
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: produces UBERON:0001090 ! synovial fluid
relationship: composed_primarily_of UBERON:0002384 {source="BTO"} ! connective tissue
relationship: produces UBERON:0001090 ! synovial fluid

[Term]
id: UBERON:0007617
name: synovial cavity of joint
namespace: uberon
def: "An anatomical cavity that surrounded_by a synovial joint." [OBOL:automatic]
synonym: "articular cavity (synovial joint)" EXACT [FMA:11356]
synonym: "cavitas articularis (junctura synovialis)" EXACT [FMA:11356]
synonym: "cavity of synovial joint" EXACT [FMA:11356]
synonym: "joint cavity" RELATED [FMA:11356]
synonym: "synovial cavity" RELATED [FMA:11356]
xref: FMA:11356
is_a: UBERON:0002553 ! anatomical cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0002217 ! synovial joint
relationship: luminal_space_of UBERON:0002217 ! synovial joint
relationship: part_of UBERON:0002217 ! synovial joint

[Term]
id: UBERON:0007625
name: pigment epithelium of eye
namespace: uberon
def: "Epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules." [MP:0005200]
subset: pheno_slim
synonym: "eye pigment epithelium" RELATED [MESH:A09.371.670]
xref: GAID:907
xref: MESH:D010857
is_a: UBERON:0019304 ! sensory organ epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000970 ! eye
relationship: part_of UBERON:0000970 ! eye

[Term]
id: UBERON:0007635
name: nucleus of medulla oblongata
namespace: uberon
def: "A neural nucleus that is part of a medulla oblongata." [OBOL:automatic]
xref: FMA:258772
xref: SCTID:304943004
is_a: UBERON:0006331 ! brainstem nucleus
is_a: UBERON:0009662 ! hindbrain nucleus
intersection_of: UBERON:0000125 ! neural nucleus
intersection_of: part_of UBERON:0001896 ! medulla oblongata
relationship: part_of UBERON:0001896 ! medulla oblongata

[Term]
id: UBERON:0007641
name: trigeminal nuclear complex
namespace: uberon
def: "The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. There is also a distinct trigeminal motor nucleus that is medial to the chief sensory nucleus[WP]." [Wikipedia:Trigeminal_nerve_nuclei]
synonym: "nuclei trigemini" RELATED OMO:0003011 [Wikipedia:Trigeminal_nerve_nuclei]
synonym: "trigeminal nuclei" EXACT [FMA:71248]
xref: BIRNLEX:4096
xref: BM:V
xref: CALOHA:TS-2077
xref: DHBA:266441713
xref: FMA:71248
xref: HBA:9203
xref: MESH:D014278 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: neuronames:2021
xref: UMLS:C0040999 {source="BIRNLEX:4096"}
xref: Wikipedia:Trigeminal_nerve_nuclei
is_a: UBERON:0007245 {source="FMA"} ! nuclear complex of neuraxis
relationship: extends_fibers_into UBERON:0001645 ! trigeminal nerve
relationship: overlaps UBERON:0003023 {source="FMA"} ! pontine tegmentum
relationship: part_of RO:0002577 ! system
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png" xsd:anyURI
property_value: UBPROP:0000012 "in MA and FMA this is part of the pons / pontime tegmentum. We weaken this to overlaps to avoid inconsistency. In NIF this is a composite structure spanning multiple regions, which is more appropriate." xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0007651
name: anatomical junction
namespace: uberon
def: "An anatomical structure that connects two structures." [http://code.google.com/p/caro2/issues/detail?id=15]
subset: common_anatomy
subset: upper_level
synonym: "anatomical junction" EXACT []
synonym: "junction" BROAD []
xref: FMA:5898
xref: SCTID:91833003
is_a: UBERON:0000061 {source="FMA"} ! anatomical structure
relationship: connects UBERON:0000061 {minCardinality="2"} ! anatomical structure
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0007652
name: esophageal sphincter
namespace: uberon
def: "A sphincter that is part of an esophagus." [http://orcid.org/0000-0002-6601-2165]
xref: SCTID:277765007
is_a: UBERON:0003832 ! esophagus muscle
is_a: UBERON:0004590 ! sphincter muscle
intersection_of: UBERON:0004590 ! sphincter muscle
intersection_of: part_of UBERON:0001043 ! esophagus
property_value: editor_note "check for specific subtypes across species. Note mammals have upper and lower, but lower is really part of cardia and thus is not classified under here" xsd:string

[Term]
id: UBERON:0007684
name: uriniferous tubule
namespace: uberon
def: "Functional unit of the kidney that forms urine, consisting of two parts, the nephron and the collecting tubule." [ISBN:0073040584]
xref: FMA:17691
is_a: UBERON:0003914 ! epithelial tube
is_a: UBERON:0004819 ! kidney epithelium
is_a: UBERON:0006555 ! excretory tube
relationship: has_part UBERON:0001232 ! collecting duct of renal tubule
relationship: has_part UBERON:0001285 ! nephron

[Term]
id: UBERON:0007687
name: kidney field
namespace: uberon
def: "Region of the embryo into the area in which the kidney rudiment will develop." [DOI:10.1371/journal.pone.0099864, GO:0072004, GOC:mtg_kidney_jan10]
synonym: "kidney anlage" RELATED [GOC:mtg_kidney_jan10]
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0006598 ! presumptive structure
is_a: UBERON:0007688 ! anlage
intersection_of: UBERON:0007688 ! anlage
intersection_of: has_potential_to_develop_into UBERON:0002113 ! kidney
relationship: has_potential_to_develop_into UBERON:0002113 ! kidney

[Term]
id: UBERON:0007688
name: anlage
namespace: uberon
def: "Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue." [FBbt:00005426, http://flybase.org/reports/FBrf0178740.html]
subset: efo_slim
synonym: "developmental field" EXACT []
synonym: "field" BROAD []
synonym: "future organ" RELATED []
synonym: "organ field" RELATED []
xref: AEO:0000170
xref: EFO:0001649
xref: EHDAA2:0003170
xref: FBbt:00005426 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: Wikipedia:Anlage_(biology)
is_a: UBERON:0000479 {source="FBbt"} ! tissue
is_a: UBERON:0005423 {source="AEO", source="FBbt"} ! developing anatomical structure

[Term]
id: UBERON:0007690
name: early pharyngeal endoderm
namespace: uberon
comment: relation conflict: ZFA vs EHDAA2. Note EHDAA2 term renamed to 'early PA endoderm'
subset: efo_slim
synonym: "early pharyngeal arch endoderm" EXACT [EHDAA2:0001457]
synonym: "pharyngeal arch endoderm" RELATED []
synonym: "pharyngeal endoderm" RELATED [ZFA:0001104]
synonym: "pharyngeal region endoderm" RELATED [EHDAA2:0001456]
xref: EFO:0003626
xref: EHDAA2:0001457
xref: EHDAA:962
xref: EMAPA:32754
xref: FMA:293087
xref: TAO:0001104
xref: ZFA:0001104
is_a: UBERON:0003258 ! endoderm of foregut
is_a: UBERON:0005291 ! embryonic tissue
relationship: part_of UBERON:0009722 {source="cjm"} ! entire pharyngeal arch endoderm
property_value: seeAlso "http://dev.biologists.org/content/128/22/4573.full" xsd:anyURI

[Term]
id: UBERON:0007719
name: bone of reproductive organ
namespace: uberon
def: "A bone that is part of a reproductive organ." [https://github.com/obophenotype/uberon/issues/1158, OBOL:automatic]
synonym: "baculum" NARROW []
synonym: "os penis/os clitoris" RELATED []
is_a: UBERON:0001474 ! bone element
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0003133 ! reproductive organ
relationship: part_of UBERON:0003133 ! reproductive organ
property_value: RO:0002161 NCBITaxon:9606 {source="Wikipedia"}

[Term]
id: UBERON:0007771
name: epidermis gland
namespace: uberon
def: "A gland that is part of a epidermis." [OBOL:automatic]
subset: grouping_class
synonym: "epidermal gland" EXACT []
synonym: "gland of epidermis" EXACT [FMA:59153]
xref: FMA:59153
is_a: UBERON:0002419 ! skin gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0001003 ! skin epidermis
relationship: part_of UBERON:0001003 ! skin epidermis

[Term]
id: UBERON:0007778
name: umbilical artery endothelium
namespace: uberon
def: "An endothelium that is part of a umbilical artery." [OBOL:automatic]
xref: BTO:0000857
is_a: UBERON:0001917 ! endothelium of artery
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0001310 ! umbilical artery
relationship: part_of UBERON:0001310 {source="BTO"} ! umbilical artery

[Term]
id: UBERON:0007779
name: transudate
namespace: uberon
def: "Any bodily fluid that has passed through a membrane such as the capillary wall, as a result of unbalanced hydrostatic and osmotic forces." [http://medical-dictionary.thefreedictionary.com/transudate]
synonym: "plasma ultrafiltrate" RELATED []
xref: FMA:12276
xref: GAID:1195
xref: MESH:D005122
xref: ncithesaurus:Transudate
is_a: UBERON:0006314 ! bodily fluid
intersection_of: UBERON:0000463 ! organism substance
intersection_of: filtered_through UBERON:0001982 ! capillary
intersection_of: has_quality PATO:0001548 ! quality of a liquid
intersection_of: transformation_of UBERON:0001969 ! blood plasma
relationship: develops_from UBERON:0001969 ! blood plasma
relationship: filtered_through UBERON:0001982 ! capillary
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: transformation_of UBERON:0001969 ! blood plasma
property_value: UBPROP:0000007 "transudative" xsd:string
property_value: UBPROP:0000010 "characteristically low in protein and cellular content (unless there has been secondary concentration)" xsd:string

[Term]
id: UBERON:0007794
name: secretion of serous gland
namespace: uberon
def: "Any fluid produced by a serous gland." [UBERON:cjm]
synonym: "serosal fluid" EXACT [Wikipedia:Serous_fluid]
synonym: "serous fluid" BROAD []
synonym: "serous gland fluid" EXACT []
xref: Wikipedia:Serous_fluid
is_a: UBERON:0000456 ! secretion of exocrine gland
is_a: UBERON:0006314 ! bodily fluid
intersection_of: UBERON:0006314 ! bodily fluid
intersection_of: produced_by UBERON:0000409 ! serous gland
relationship: produced_by UBERON:0000409 ! serous gland

[Term]
id: UBERON:0007798
name: vascular system
namespace: uberon
def: "Anatomical system that consists of all blood and lymph vessels." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
xref: BTO:0001085
xref: CALOHA:TS-2053
xref: EHDAA2:0004520
xref: EMAPA:35905
xref: MA:0002718
xref: NCIT:C33854
xref: UMLS:C0489903 {source="ncithesaurus:Vascular_System"}
is_a: UBERON:0000467 ! anatomical system
relationship: part_of UBERON:0004535 {source="MA"} ! cardiovascular system
property_value: editor_note "consider merging with vasculature" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The cardiovascular and lymphatic systems, collectively[ncithesaurus:Vascular_System]." xsd:string {source="ncithesaurus:Vascular_System"}
property_value: UBPROP:0000012 "in both MA and BTO, the arterial system and venous sytem are subtypes of the vascular system" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0007806
name: connecting stalk
namespace: uberon
def: "A bridge of mesoderm connecting the caudal end of the young embryo with the trophoblastic tissues; the precursor of the umbilical cord." [http://medical-dictionary.thefreedictionary.com/]
xref: BTO:0004705
xref: NCIT:C34132
xref: UMLS:C1516792 {source="ncithesaurus:Connecting_Stalk"}
is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure
relationship: develops_from UBERON:0005728 {source="EHDAA2"} ! extraembryonic mesoderm
property_value: editor_note "TODO - this is currently defined as a bridge of mesoderm, but in EHDAA2 is extraembryonic structure split into mesoderm and blood vessels" xsd:string

[Term]
id: UBERON:0007807
name: connecting stalk vasculature
namespace: uberon
def: "A vasculature that is part of a connecting stalk." [OBOL:automatic]
synonym: "connecting stalk blood vessel" RELATED []
synonym: "connecting stalk blood vessels" EXACT [EHDAA2:0000313]
synonym: "vasculature of connecting stalk" RELATED []
xref: EHDAA2:0000313
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0007806 ! connecting stalk
relationship: develops_from UBERON:0011921 {source="EHDAA2"} ! connecting stalk blood islands
relationship: part_of UBERON:0007806 ! connecting stalk

[Term]
id: UBERON:0007808
name: adipose tissue of abdominal region
namespace: uberon
def: "Adipose tissue that is located in the abdominal region. This includes any subcutaneous fat, visceral fat or encapsulated adipose tissue depots." [CALOHA:paula, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/259, MGI:csmith]
subset: efo_slim
synonym: "abdominal adipose tissue" RELATED [BTO:0004041]
synonym: "abdominal fat" RELATED [BTO:0004041]
synonym: "intra-abdominal fat" RELATED [BTO:0004041]
xref: CALOHA:TS-0002
xref: EFO:0003771
is_a: UBERON:0001013 ! adipose tissue
is_a: UBERON:0003567 ! abdomen connective tissue
intersection_of: UBERON:0001013 ! adipose tissue
intersection_of: part_of UBERON:0000916 ! abdomen
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cindyJax
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/paulacalipho

[Term]
id: UBERON:0007811
name: craniocervical region
namespace: uberon
def: "The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae." [https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "cephalic area" RELATED [https://github.com/obophenotype/uberon/issues/379]
synonym: "cephalic part of animal" RELATED [Wikipedia:Head]
synonym: "cephalic region" RELATED [https://github.com/obophenotype/uberon/issues/379]
synonym: "head and neck" RELATED [FMA:280881]
synonym: "head or neck" RELATED []
xref: CALOHA:TS-2356
xref: EV:0100009
xref: FMA:280881
xref: galen:HeadAndNeck
xref: MA:0000006
xref: NCIT:C12418
xref: SCTID:361355005
xref: UMLS:C0460004 {source="ncithesaurus:Head_and_Neck"}
xref: WikipediaCategory:Head_and_neck
is_a: UBERON:0000475 {source="MA"} ! organism subdivision
relationship: has_part UBERON:0000033 ! head
relationship: has_part UBERON:0000974 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! neck
relationship: has_part UBERON:0006562 ! pharynx
relationship: part_of UBERON:0000153 ! anterior region of body
relationship: part_of UBERON:0013702 ! body proper

[Term]
id: UBERON:0007812
name: post-anal tail
namespace: uberon
def: "A tail that extends from the posterior tip of the organism to the anus, contains muscle and skeleton." [https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
subset: vertebrate_core
synonym: "muscular postanal tail" EXACT []
synonym: "post-anal fin tail" NARROW SENSU [http://purl.oboibrary.org/obo/uberon/tracker/185]
synonym: "post-vent region" RELATED [TAO:0001117]
synonym: "postanal tail" EXACT []
xref: AAO:0010338
xref: EMAPA:16748
xref: MA:0000008
xref: NCIT:C77663
xref: TAO:0001117
xref: UMLS:C0039259 {source="ncithesaurus:Tail"}
xref: XAO:0003026
xref: ZFA:0001117
is_a: UBERON:0002415 ! tail
intersection_of: UBERON:0002415 ! tail
intersection_of: part_of UBERON:0006071 ! caudal region
relationship: capable_of_part_of GO:0007626 ! locomotory behavior
relationship: develops_from UBERON:0007144 ! embryonic post-anal tail
relationship: only_in_taxon NCBITaxon:7711 {notes="possible exception in hemichordates", source="cjm"} ! Chordata
relationship: part_of UBERON:0006071 ! caudal region
relationship: transformation_of UBERON:0007144 ! embryonic post-anal tail
property_value: RO:0002161 NCBITaxon:314295
property_value: UBPROP:0000001 "Anatomical structure that is the terminal, flexible posterior appendage of the organism.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010338", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "Organism subdivision which is the part of the body posterior to the vent which includes the anal and caudal fins.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001117", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000008 "present at some time in chordate life history (eg in Urochordates, present only in free-swimming larvae). Function: propellor locomotion (in some species)" xsd:string

[Term]
id: UBERON:0007823
name: appendage girdle region
namespace: uberon
alt_id: UBERON:0007824
def: "An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc)." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003]
synonym: "fin girdle" RELATED SENSU []
synonym: "fin girdle region" RELATED SENSU []
synonym: "girdle" BROAD []
synonym: "girdle region" BROAD []
synonym: "limb girdle" RELATED SENSU []
synonym: "limb girdle region" RELATED SENSU []
xref: EMAPA:37854 {source="MA:th"}
xref: FMA:24874
xref: VSAO:0000303
is_a: UBERON:0000475 ! organism subdivision
intersection_of: UBERON:0000475 ! organism subdivision
intersection_of: has_skeleton UBERON:0010719 ! girdle skeleton
relationship: has_skeleton UBERON:0010719 ! girdle skeleton
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0010707 ! appendage girdle complex
property_value: curator_notes "this encompasses non-skeletal tissue" xsd:string
property_value: UBPROP:0000001 "An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). There are only two instances of appendage girdle regions per organism.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000303", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"}

[Term]
id: UBERON:0007826
name: peritoneal mesentery
namespace: uberon
def: "Mesentery that is located in the peritoneum." [UBERON:cjm]
xref: FMA:20570
xref: TAO:0005129
xref: XAO:0000138
xref: ZFA:0005129
is_a: UBERON:0002095 ! mesentery
is_a: UBERON:0002358 ! peritoneum
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0002358 ! peritoneum
relationship: part_of UBERON:0001178 {source="FMA"} ! visceral peritoneum

[Term]
id: UBERON:0007828
name: girdle bone/zone
namespace: uberon
def: "A bone that is part of a appendage girdle region." [OBOL:automatic]
synonym: "girdle bone" EXACT [MA:0000291]
xref: EMAPA:35379
xref: MA:0000291
is_a: UBERON:0010740 ! bone of appendage girdle complex
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0007823 ! appendage girdle region
relationship: part_of UBERON:0010719 ! girdle skeleton

[Term]
id: UBERON:0007829
name: pectoral girdle bone
namespace: uberon
def: "A bone that is part of a pectoral girdle region." [OBOL:automatic]
subset: human_reference_atlas
subset: vertebrate_core
synonym: "bone of pectoral girdle" EXACT []
xref: EMAPA:35669
xref: MA:0000292
is_a: UBERON:0007828 {source="MA"} ! girdle bone/zone
is_a: UBERON:0010741 ! bone of pectoral complex
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0001421 ! pectoral girdle region
relationship: part_of UBERON:0007831 ! pectoral girdle skeleton
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0007830
name: pelvic girdle bone/zone
namespace: uberon
def: "A bone element or fused bone that is part of pelvic girdle." [https://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
subset: pheno_slim
subset: vertebrate_core
synonym: "bone of pelvic girdle" EXACT []
synonym: "pelvic girdle bone" EXACT [MA:0000293]
xref: EMAPA:18028
xref: MA:0000293
xref: NCIT:C33287
xref: SCTID:426214007
xref: UMLS:C0030786 {source="ncithesaurus:Pelvic_Bone"}
is_a: UBERON:0003828 ! abdominal segment bone
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005179 ! pelvic region element
is_a: UBERON:0005913 ! zone of bone organ
is_a: UBERON:0007828 {source="MA"} ! girdle bone/zone
is_a: UBERON:0010742 ! bone of pelvic complex
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0007832 ! pelvic girdle skeleton
relationship: part_of UBERON:0007832 ! pelvic girdle skeleton
property_value: editor_note "check sacrum, coccyx (MA does NOT include these)" xsd:string
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "typically the ilium, ischium and pubis. These can alternately be considered individual bones, or zones of a single fused bone" xsd:string

[Term]
id: UBERON:0007831
name: pectoral girdle skeleton
namespace: uberon
def: "A subdivision of a limb or fin skeleton consisting of bones which connects the upper limb or fin to the axial skeleton on each side. It consists of the clavicle and scapula in humans and, in those species with three bones in the pectoral girdle, the coracoid. Some mammalian species (e.g. the dog and the horse) have only the scapula. In humans, the only joints between the shoulder girdle and axial skeleton are the sternoclavicular joints on each side. No joint exists between each scapula and the rib cage; instead the muscular connection between the two permits relatively great mobility of the shoulder girdle in relation to the pelvic girdle. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular[WP]. Examples: There are only two instances, right and left pectoral girdle skeletons." [Wikipedia:Pectoral_girdle]
subset: efo_slim
subset: vertebrate_core
synonym: "cingulum pectorale" RELATED OMO:0003011 [Wikipedia:Pectoral_girdle]
synonym: "pectoral girdle" RELATED INCONSISTENT [VSAO:0000156]
synonym: "scapular girdle" RELATED [TAO:0000407]
synonym: "skeletal parts of pectoral girdle" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "skeleton of pectoral girdle" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: AAO:0000422
xref: AAO:0000754
xref: EFO:0000946
xref: EHDAA2:0001420
xref: FMA:24141
xref: MAT:0000181
xref: MIAA:0000181
xref: NCIT:C33547
xref: TAO:0000407
xref: UMLS:C0427245 {source="ncithesaurus:Shoulder_Girdle"}
xref: VHOG:0001156
xref: VSAO:0000156
xref: Wikipedia:Pectoral_girdle
xref: XAO:0003063
xref: ZFA:0000407
is_a: UBERON:0010719 ! girdle skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: part_of UBERON:0001421 ! pectoral girdle region
intersection_of: skeleton_of UBERON:0001421 ! pectoral girdle region
relationship: part_of UBERON:0001421 ! pectoral girdle region
relationship: part_of UBERON:0012475 ! skeleton of pectoral complex
relationship: skeleton_of UBERON:0001421 ! pectoral girdle region
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/22/Pectoral_girdle_front_diagram.svg" xsd:anyURI
property_value: UBPROP:0000001 "Anatomical cluster of paired dermal and endochondral bones that attaches to the dorso-posterior part of the cranium, and support the radials and pectoral fin. It consists of two components: the primary pectoral girdle consisting of the endochondral coracoid, scapula and mesocoracoid bones, and the secondary pectoral girdle consisting of the dermal posttemporal, supracleithrum, cleithrum and poscleithrum(thra) bones.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000407", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000001 "Girdle skeleton consisting of a set of bones linking the axial series to the forelimb/fin skeleton and offering anchoring areas for forelimb/fin and caudal musculature.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000156", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"}
property_value: UBPROP:0000001 "Skeletal structure immediately behind the head attached to the vertebral column by muscles and supporting the forelimbs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000422", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000003 "The pectoral girdle is clearly of dual origin, composed of dermal as well as endochondral bones. The endochondral component, the scapulocoracoid, evolved by fusion or enlargment of several basal fin elements. (...) The dermal component of the shoulder girdle evolved from dermal bones of the body's surface. (...) Like endochondral bones, these dermal bones were passed along to tetrapods (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001156", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.336 and Figure 9.18", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "Note that the VSAO and many ontologies use the label 'pectoral girdle' to denote the skeletal region specifically." xsd:string {external_ontology="VSAO"}

[Term]
id: UBERON:0007832
name: pelvic girdle skeleton
namespace: uberon
def: "Skeletal subdivision consisting of a set of bones linking the axial series to the hindlimb zeugopodium and offering anchoring areas for hindlimb and caudal musculature." [VSAO:0000155, Wikipedia:Pelvis]
subset: efo_slim
subset: vertebrate_core
synonym: "pelvic girdle" RELATED INCONSISTENT [VSAO:0000155]
synonym: "pelvic girdle skeleton" EXACT [VSAO:0000155]
synonym: "skeletal parts of pelvic girdle" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "skeleton of pelvic girdle" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: AAO:0000426
xref: AAO:0000768
xref: EFO:0000947
xref: EHDAA2:0001426
xref: EHDAA:7149
xref: EHDAA:8324
xref: EMAPA:18028
xref: FMA:87592
xref: galen:PelvicGirdle
xref: http://people.eku.edu/ritchisong/pectoralgirdles.gif
xref: MAT:0000182
xref: MIAA:0000182
xref: TAO:0000565
xref: VHOG:0000305
xref: VSAO:0000155
xref: Wikipedia:Pelvis
xref: XAO:0003064
xref: ZFA:0000565
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0010719 ! girdle skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: part_of UBERON:0001271 ! pelvic girdle region
intersection_of: skeleton_of UBERON:0001271 ! pelvic girdle region
relationship: develops_from UBERON:0010377 {source="PMID:21455939"} ! mesenchyme from somatopleure
relationship: part_of UBERON:0001271 ! pelvic girdle region
relationship: part_of UBERON:0012476 ! skeleton of pelvic complex
relationship: skeleton_of UBERON:0001271 ! pelvic girdle region
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/fe/Gray242.png" xsd:anyURI
property_value: editor_note "need to resolve whether this is a paired structure or a single belt (Paired in FMA - implicitly paired in VSAO)" xsd:string
property_value: UBPROP:0000001 "Anatomical cluster by which the hind limbs are supported and attached to the vertebral column.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000426", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000001 "Anatomical cluster that consists of the paired basipterygia which support the pelvic fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000565", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000001 "Girdle skeleton consisting of a set of bones linking the axial series to the hindlimb/fin skeleton and offering anchoring areas for hindlimb/fin and caudal musculature.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000155", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"}
property_value: UBPROP:0000003 "The pelvic girdle is never joined by contributions of dermal bone. From its first appearance in placoderms, the pelvic girdle is exclusively endoskeletal. It arose from pterygiophores, perhaps several times, in support of the fin.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000305", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.333", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "Note that the VSAO and many ontologies use the label 'pelvic girdle' to denote the skeletal region specifically. We place the EHDAA2 class here, note that this includes the pre-cartilage condensation as parts" xsd:string {external_ontology="VSAO"}

[Term]
id: UBERON:0007842
name: membrane bone
namespace: uberon
def: "Bone element that arises as a result of intramembranous ossification." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/267, VSAO:0000023]
synonym: "membrane bones" RELATED OMO:0003004 [ZFA:0001636]
xref: AEO:0000085
xref: EHDAA2:0003085
xref: TAO:0001645
xref: VSAO:0000023
xref: XAO:0004014
xref: ZFA:0001636
is_a: UBERON:0001474 {source="VSAO"} ! bone element
relationship: output_of GO:0001957 ! intramembranous ossification
property_value: UBPROP:0000001 "Bone element that arises as a result of intramembranous ossification.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000023", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"}
property_value: UBPROP:0000001 "Intramembranous bone that forms deep in the organism.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001645", ontology="TAO", source="TAO:wd"}

[Term]
id: UBERON:0007844
name: cartilage element
namespace: uberon
def: "Skeletal element that is composed of cartilage tissue and may be permanent or transient." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000000]
subset: organ_slim
subset: pheno_slim
synonym: "cartilage" RELATED [VSAO:0000000]
synonym: "cartilage organ" EXACT [FMA:55107]
synonym: "cartilaginous element" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "chondrogenic element" EXACT [VSAO:0000000]
xref: AAO:0011130
xref: CALOHA:TS-0118
xref: EMAPA:32730
xref: FMA:55107
xref: VSAO:0000000
xref: XAO:0004013
xref: ZFA:0001501
is_a: UBERON:0004765 {source="VSAO"} ! skeletal element
intersection_of: UBERON:0004765 ! skeletal element
intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue
relationship: composed_primarily_of UBERON:0002418 ! cartilage tissue
relationship: develops_from UBERON:0005863 {source="VSAO"} ! cartilaginous condensation
relationship: has_part UBERON:0002418 {source="VSAO"} ! cartilage tissue
property_value: UBPROP:0000012 "TAO still mixes tissue and element" xsd:string {external_ontology="TAO"}

[Term]
id: UBERON:0007845
name: regular connective tissue
namespace: uberon
def: "Connective tissue, which consists of fibroblasts, the intercellular matrix of which contains a regular network of collagen and elastic fiber bundles. Examples: bone (tissue), cartilage (tissue), dense regular connective tissue." [FMA:20103]
xref: FMA:20103
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0002384 {source="FMA"} ! connective tissue
disjoint_from: UBERON:0011821 ! irregular connective tissue
relationship: has_part CL:0000057 ! fibroblast
relationship: has_part GO:0071953 ! elastic fiber
relationship: has_part UBERON:0011860 ! collection of collagen fibrils
property_value: editor_note "the connective tissue hierarchy largely follows FMA with definitions from VSAO. Note that in FMA, loose-CT is irregular-CT. This means regular-CT is necessarily equivalent to dense-regular-CT (assuming a JEPD classification)." xsd:string

[Term]
id: UBERON:0007846
name: dense regular connective tissue
namespace: uberon
def: "Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts)." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000050]
synonym: "dense fibrous connective tissue" EXACT [FMA:64781]
synonym: "dense regular collagenous connective tissue" EXACT [FMA:64781]
synonym: "dense regular collagenous tissue" EXACT [FMA:64781]
synonym: "regular dense connective tissue" EXACT []
synonym: "typus regularis (textus connectivus collagenosus compactus)" EXACT [FMA:64781]
xref: FMA:64781
xref: NCIT:C33453
xref: SCTID:22560007
xref: UMLS:C0225333 {source="ncithesaurus:Regular_Dense_Connective_Tissue"}
xref: VSAO:0000050
xref: Wikipedia:Dense_regular_connective_tissue
xref: XAO:0004030
is_a: UBERON:0007845 {source="FMA"} ! regular connective tissue
is_a: UBERON:0011823 {source="ncithesaurus"} ! dense connective tissue
intersection_of: UBERON:0007845 ! regular connective tissue
intersection_of: composed_primarily_of UBERON:0011860 ! collection of collagen fibrils
intersection_of: has_part GO:0071953 ! elastic fiber
property_value: UBPROP:0000001 "Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts).[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000050", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"}
property_value: UBPROP:0000001 "Regular connective tissue, the intercellular matrix of which consists predominantly of collagen fiber bundles arranged in parallel arrays.[FMA]" xsd:string {date_retrieved="2012-08-29", external_class="FMA:64781", ontology="FMA"}

[Term]
id: UBERON:0007914
name: bone of craniocervical region
namespace: uberon
def: "A bone that is part of a craniocervical region." [OBOL:automatic]
synonym: "cranial bone" RELATED []
synonym: "head or neck bone" EXACT [MA:0000569]
xref: EMAPA:37245 {source="MA:th"}
xref: MA:0000569
is_a: UBERON:0001474 {source="MA"} ! bone element
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0007811 ! craniocervical region
relationship: part_of UBERON:0007811 {source="MA"} ! craniocervical region

[Term]
id: UBERON:0008001
name: irregular bone
namespace: uberon
def: "The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid." [Wikipedia:Irregular_bone]
synonym: "os irregulare" EXACT []
synonym: "os irregulare" RELATED OMO:0003011 [Wikipedia:Irregular_bone]
xref: FMA:7477
xref: NCIT:C32881
xref: SCTID:421560006
xref: UMLS:C0502414 {source="ncithesaurus:Irregular_Bone"}
xref: Wikipedia:Irregular_bone
is_a: UBERON:0001474 {source="FMA"} ! bone element

[Term]
id: UBERON:0008114
name: joint of girdle
namespace: uberon
def: "A skeletal joint that is part of a appendage girdle region." [OBOL:automatic]
subset: grouping_class
synonym: "girdle joint" EXACT [OBOL:automatic]
xref: MA:0001505
is_a: UBERON:0000982 {source="MA"} ! skeletal joint
intersection_of: UBERON:0000982 ! skeletal joint
intersection_of: part_of UBERON:0007823 ! appendage girdle region
relationship: connects UBERON:0007828 ! girdle bone/zone
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0007823 ! appendage girdle region

[Term]
id: UBERON:0008115
name: surface of cartilage
namespace: uberon
def: "An anatomical surface that is part of a cartilage element." [OBOL:automatic]
synonym: "cartilage surface" EXACT [FMA:76668]
xref: FMA:76668
is_a: UBERON:0036215 ! anatomical surface region
intersection_of: UBERON:0036215 ! anatomical surface region
intersection_of: bounding_layer_of UBERON:0007844 ! cartilage element
relationship: bounding_layer_of UBERON:0007844 ! cartilage element
relationship: part_of UBERON:0007844 ! cartilage element

[Term]
id: UBERON:0008193
name: pneumatized bone
namespace: uberon
def: "A bone that is hollow or contains many air cells, such as the mastoid process of the temporal bone[TMD]." [http://www.medilexicon.com/medicaldictionary.php?t=11303]
synonym: "hollow bone" RELATED []
synonym: "os pneumaticum" EXACT [FMA:7478]
synonym: "pneumatic bone" EXACT [FMA:7478]
xref: FMA:7478
xref: galen:PneumaticBone
xref: SCTID:333008005
xref: Wikipedia:Skeletal_pneumaticity
is_a: UBERON:0001474 ! bone element
intersection_of: UBERON:0001474 ! bone element
intersection_of: has_part UBERON:0010528 ! pneumatic cavity of bone
relationship: has_part UBERON:0010528 ! pneumatic cavity of bone
property_value: editor_note "subclasses of this should be checked for taxonomic consistency" xsd:string
property_value: UBPROP:0000008 "Skeletal pneumaticity is the presence of air spaces within bones. Skeletal pneumaticity exists only in synapsids and archosaurs. It is generally produced during development by excavation of bone by pneumatic diverticula (air sacs) from an air-filled space such as the lungs or nasal cavity. Pneumatization is highly variable between individuals, and bones not normally pneumatized can become pneumatized in pathological development. Pneumatization occurs in the skulls of mammals, crocodilians and birds among extant groups, as well as extinct archosaurs including the dinosaurs and pterosaurs. Pneumatic spaces include the paranasal sinuses and some of the mastoid cells[WP]. [Wikipedia:Skeletal_pneumaticity]" xsd:string

[Term]
id: UBERON:0008196
name: muscle of pectoral girdle
namespace: uberon
def: "Any muscle organ that is part of a pectoral girdle region." [OBOL:automatic]
subset: pheno_slim
synonym: "muscle of shoulder girdle" EXACT [FMA:37347]
synonym: "pectoral girdle muscle" EXACT [FMA:37347]
xref: EMAPA:17748
xref: FMA:37347
is_a: UBERON:0010891 ! pectoral complex muscle
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0001421 ! pectoral girdle region
relationship: part_of UBERON:0004471 ! musculature of pectoral girdle
property_value: UBPROP:0000012 "EMAPA has both non-skeletal and skeletal types, with the non-skeletal also including a chest muscle, so we place the skeletal class here as the most accurate" xsd:string {external_ontology="EMAPA"}

[Term]
id: UBERON:0008203
name: pelvic cavity
namespace: uberon
def: "The part of the ventral body cavity that is within the pelvis." [UBERON:cjm]
synonym: "cavitas pelvis" RELATED OMO:0003011 [Wikipedia:Pelvic_cavity]
synonym: "space of pelvic compartment" EXACT [FMA:9738]
xref: EMAPA:37235 {source="MA:th"}
xref: FMA:9738
xref: MA:0003089
xref: SCTID:281903009
xref: Wikipedia:Pelvic_cavity
is_a: UBERON:0002553 ! anatomical cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0002355 ! pelvic region of trunk
intersection_of: part_of UBERON:0002323 ! coelemic cavity lumen
relationship: luminal_space_of UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0035819 ! abdominopelvic cavity
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI

[Term]
id: UBERON:0008229
name: craniocervical region musculature
namespace: uberon
def: "Musculature system of the pharyngeal and head regions." [ZFA:0000328, ZFA:curator]
synonym: "head muscles" RELATED [ZFA:0000328]
synonym: "head or neck muscle" EXACT [MA:0000571]
synonym: "head or neck muscle" RELATED [MA:0000571]
xref: EMAPA:37259 {source="MA:th"}
xref: MA:0000571
xref: TAO:0000328
xref: ZFA:0000328
is_a: UBERON:0001015 {source="MA"} ! musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0007811 ! craniocervical region
relationship: part_of UBERON:0007811 {source="MA"} ! craniocervical region
property_value: UBPROP:0000012 "in MA this is restricted to skeletal muscles" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0008231
name: dorsal thoracic segment of trunk
namespace: uberon
def: "Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax." [FMA:24217]
synonym: "back of thorax" RELATED [FMA:24217]
synonym: "dorsum of thorax" EXACT [FMA:24217]
synonym: "posterior part of thorax" EXACT [FMA:24217]
synonym: "thoracic back" EXACT [FMA:24217]
synonym: "thoracic part of back" EXACT [FMA:24217]
synonym: "upper back" EXACT [MA:0000028]
xref: EMAPA:37234 {source="MA:th"}
xref: FMA:24217
xref: MA:0000028
xref: SCTID:362666008
is_a: UBERON:0000475 ! organism subdivision
relationship: part_of UBERON:0000915 {source="FMA", source="MA"} ! thoracic segment of trunk
relationship: part_of UBERON:0011270 {source="FMA"} ! dorsal trunk

[Term]
id: UBERON:0008243
name: upper back muscle
namespace: uberon
def: "A muscle of back that is part of a dorsal thoracic segment of trunk." [OBOL:automatic]
xref: EMAPA:37261 {source="MA:th"}
xref: MA:0000508
xref: SCTID:305071003
is_a: UBERON:0002324 ! muscle of back
is_a: UBERON:0003830 {source="MA"} ! thoracic segment muscle
intersection_of: UBERON:0002324 ! muscle of back
intersection_of: part_of UBERON:0008231 ! dorsal thoracic segment of trunk
relationship: part_of UBERON:0008231 {source="MA"} ! dorsal thoracic segment of trunk

[Term]
id: UBERON:0008307
name: heart endothelium
namespace: uberon
def: "An endothelium that is part of a heart [Automatically generated definition]." [OBOL:automatic]
synonym: "cardiac endothelium" RELATED [BTO:0004293]
xref: BTO:0004293
is_a: UBERON:0004852 ! cardiovascular system endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart
property_value: curator_notes "this class includes any endothelia that are part of the heart. This might include the endocardial epithelia, as well as endothelia of vessels that are considered strictly part of the heart (e.g. outflow tract). As a grouping class, this may lack utility, and pending review this class may be obsoleted. For annotation consider a more specific class." xsd:string

[Term]
id: UBERON:0008324
name: erectile tissue
namespace: uberon
def: "With numerous vascular spaces that may become engorged with blood." [Wikipedia:Erectile_tissue]
comment: Examples: corpus cavernosum or penis or clitoris
xref: Wikipedia:Erectile_tissue
is_a: UBERON:0000479 ! tissue
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria

[Term]
id: UBERON:0008331
name: clitoral smooth muscle
namespace: uberon
def: "A smooth muscle tissue that is part of a clitoris." [OBOL:automatic]
synonym: "clitoris smooth muscle" RELATED [BTO:0005000]
xref: BTO:0005000
is_a: UBERON:0001135 ! smooth muscle tissue
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0002411 ! clitoris
relationship: part_of UBERON:0002411 ! clitoris

[Term]
id: UBERON:0008339
name: microvascular endothelium
namespace: uberon
xref: BTO:0003122
is_a: UBERON:0004638 ! blood vessel endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:8410081 ! blood microvessel
relationship: part_of UBERON:8410081 ! blood microvessel
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/2186" xsd:string

[Term]
id: UBERON:0008342
name: intestinal villus of duodenum
namespace: uberon
def: "An intestinal villus in the duodenum." [OBOL:automatic]
xref: FMA:63300
is_a: UBERON:0001213 ! intestinal villus
intersection_of: UBERON:0001213 ! intestinal villus
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: part_of UBERON:0000320 ! duodenal mucosa

[Term]
id: UBERON:0008346
name: duodenal epithelium
namespace: uberon
def: "An epithelium that is part of a duodenum." [OBOL:automatic]
subset: human_reference_atlas
synonym: "epithelium of duodenum" EXACT [FMA:17231]
xref: CALOHA:TS-2087
xref: EMAPA:19078
xref: FMA:17231
xref: MA:0003208
xref: SCTID:66036002
is_a: UBERON:0013636 ! epithelium of intestinal villus
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: part_of UBERON:0008342 {source="FMA"} ! intestinal villus of duodenum
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0008429
name: cervical vertebral foramen
namespace: uberon
def: "A vertebral foramen that is part of a cervical vertebra." [OBOL:automatic]
xref: FMA:13480
xref: SCTID:280833008
is_a: UBERON:0001131 ! vertebral foramen
is_a: UBERON:0005744 ! bone foramen
intersection_of: UBERON:0001131 ! vertebral foramen
intersection_of: part_of UBERON:0002413 ! cervical vertebra
relationship: part_of UBERON:0002413 ! cervical vertebra

[Term]
id: UBERON:0008432
name: thoracic vertebral foramen
namespace: uberon
def: "A vertebral foramen that is part of a thoracic vertebra." [OBOL:automatic]
xref: FMA:9143
xref: SCTID:280834002
is_a: UBERON:0001131 ! vertebral foramen
is_a: UBERON:0005744 ! bone foramen
intersection_of: UBERON:0001131 ! vertebral foramen
intersection_of: part_of UBERON:0002347 ! thoracic vertebra
relationship: part_of UBERON:0002347 ! thoracic vertebra

[Term]
id: UBERON:0008780
name: inner cell mass derived epiblast
namespace: uberon
def: "An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers." [MP:0003886]
comment: The epiblast cells (appearing on day 8 of human embryonic development) make up a columnar epithelium with dense microvilli on the apical surface. During gastrulation, the epiblast cells undergo epithelial-to-mesenchymal transition and delaminate to become the loose mesenchyme of the primitive streak. The epiblast is present in postimplantation mouse embryos between E5.5-E7.5.
subset: early_development
subset: pheno_slim
synonym: "embryonic epiblast" RELATED [MP:0003886]
xref: EHDAA2:0000444
xref: EHDAA:42
xref: EHDAA:75
xref: EMAPA:16050
xref: NCIT:C34164
xref: UMLS:C1516906 {source="ncithesaurus:Epiblast"}
is_a: UBERON:0002532 ! epiblast (generic)
intersection_of: UBERON:0002532 ! epiblast (generic)
intersection_of: develops_from UBERON:0000087 ! inner cell mass
relationship: develops_from UBERON:0000087 {source="Wikipedia"} ! inner cell mass
relationship: part_of UBERON:0000091 ! bilaminar disc

[Term]
id: UBERON:0008811
name: intromittent organ
namespace: uberon
def: "An external organ of a male organism that is specialized to deliver sperm during copulation. Intromittent organs are found most often in terrestrial species, as most aquatic species fertilize their eggs externally, although there are exceptions[WP]." [Wikipedia:Intromittent_organ]
subset: grouping_class
subset: organ_slim
synonym: "aedeagus" NARROW SENSU [FBbt:00004850]
synonym: "copulatory organ" RELATED []
synonym: "penis" NARROW []
xref: AAO:0010255
xref: FBbt:00004850 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: HAO:0000091
xref: TAO:0002036
xref: TGMA:0000585
xref: Wikipedia:Intromittent_organ
is_a: UBERON:0003135 ! male reproductive organ
relationship: capable_of_part_of GO:0007620 ! copulation
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
property_value: curator_notes "this is a broad grouping class connecting a number of different analagous organs by their function. We place the insect aedeagus here rather than penis, although this is somewhat arbitrary given the broadness of the current definition" xsd:string
property_value: UBPROP:0000001 "Surface structure that is an external structure of a male organism through which sperm is transferred to a female organism during mating.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002036", ontology="TAO", source="TAO:wd"}

[Term]
id: UBERON:0008814
name: pharyngeal arch system
namespace: uberon
def: "A transient embryonic complex that comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming, which may include (depending on species) the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear[GO,modified]." [GO:0060037, GOC:dph]
synonym: "embryonic pharyngeal complex" EXACT []
synonym: "pharyngeal apparatus" EXACT []
synonym: "pharyngeal arch complex" RELATED []
synonym: "pharyngeal arch region" RELATED [EHDAA2:0000187]
synonym: "pharyngeal arches and clefts" RELATED []
synonym: "pharyngeal complex" RELATED []
synonym: "pharyngeal system" EXACT [GO:0060037]
xref: EHDAA2:0000187
xref: FMA:293041
xref: NCIT:C34248
xref: UMLS:C1519038 {source="ncithesaurus:Pharyngeal_Apparatus"}
is_a: UBERON:0034921 ! multi organ part structure
relationship: only_in_taxon NCBITaxon:7711 ! Chordata
relationship: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0009145 ! pharyngeal region of foregut
property_value: editor_note "Currently defined in a vertebrate specific manner. The arch system has origins in basal deuterostomes, consider generalizing" xsd:string

[Term]
id: UBERON:0008816
name: embryonic head
namespace: uberon
def: "A head that is part of a embryo." [OBOL:automatic]
subset: non_informative
xref: CALOHA:TS-0246
xref: FBbt:00000155 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:293011
is_a: UBERON:0000033 ! head
intersection_of: UBERON:0000033 ! head
intersection_of: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0000922 ! embryo

[Term]
id: UBERON:0008823
name: neural tube derived brain
namespace: uberon
def: "A brain that develops_from a neural tube." [https://github.com/obophenotype/uberon/issues/338, OBOL:automatic]
synonym: "vertebrate brain" NARROW []
is_a: UBERON:0000489 {source="ZFA"} ! cavitated compound organ
is_a: UBERON:0000955 ! brain
intersection_of: UBERON:0000955 ! brain
intersection_of: develops_from UBERON:0001049 ! neural tube
relationship: develops_from UBERON:0001049 ! neural tube
relationship: part_of UBERON:0000033 {source="FMA"} ! head
property_value: editor_note "a reasoner should automatically classify all the vertebrate ontology brain classes here" xsd:string
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/338" xsd:anyURI

[Term]
id: UBERON:0008824
name: duct of epididymis
namespace: uberon
def: "Any duct branching of of the main epididymis duct." [http://orcid.org/0000-0002-6601-2165]
synonym: "epididymal duct" EXACT [MA:0001735]
synonym: "epididymis duct" EXACT [FMA:18297]
xref: EMAPA:36525
xref: FMA:18297
xref: MA:0001735
xref: NCIT:C32484
xref: SCTID:279623004
xref: UMLS:C0458632 {source="ncithesaurus:Duct_of_the_Epididymis"}
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005904 ! duct of male reproductive system
intersection_of: UBERON:0000058 ! duct
intersection_of: branching_part_of UBERON:0001301 ! epididymis
relationship: branching_part_of UBERON:0001301 ! epididymis
relationship: part_of UBERON:0001301 {source="FMA"} ! epididymis

[Term]
id: UBERON:0008835
name: hepatic diverticulum
namespace: uberon
def: "An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts." [http://www.stembook.org/node/512, MP:MP]
subset: pheno_slim
synonym: "diverticulum hepaticum" RELATED OMO:0003011 [Wikipedia:Hepatic_diverticulum]
synonym: "liver diverticulum" EXACT [XAO:0000101]
xref: AAO:0011057
xref: EHDAA2:0000740
xref: EHDAA:1530
xref: NCIT:C34187
xref: UMLS:C1512407 {source="ncithesaurus:Hepatic_Diverticulum"}
xref: Wikipedia:Hepatic_diverticulum
xref: XAO:0000101
is_a: UBERON:0004185 ! endodermal part of digestive tract
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac
is_a: UBERON:0009497 ! epithelium of foregut-midgut junction
is_a: UBERON:0009854 ! digestive tract diverticulum
relationship: develops_from UBERON:0003894 {source="EHDAA2"} ! liver primordium
relationship: part_of UBERON:0004161 {notes="caudal part", source="EHDAA2"} ! septum transversum
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/4/4f/Gray1088.png" xsd:anyURI
property_value: UBPROP:0000008 "in mice, the hepatic diverticulum forms by E9 and expands into an obvious liver bud by E10" xsd:string
property_value: UBPROP:0000011 "The caudal part of the septum transversum is invaded by the hepatic diverticulum which divides within it to form the liver and thus gives rise to the ventral mesentery of the foregut." xsd:string

[Term]
id: UBERON:0008836
name: liver bud
namespace: uberon
xref: BTO:0001642
is_a: UBERON:0004185 ! endodermal part of digestive tract
is_a: UBERON:0007499 {source="cjm"} ! epithelial sac
is_a: UBERON:0009497 ! epithelium of foregut-midgut junction
is_a: UBERON:0009854 ! digestive tract diverticulum
relationship: develops_from UBERON:0008835 {source="http://www.stembook.org/node/512"} ! hepatic diverticulum

[Term]
id: UBERON:0008846
name: skeletal ligament
namespace: uberon
def: "Dense regular connective tissue connecting two or more adjacent skeletal elements[VSAO,modified]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, http://orcid.org/0000-0002-6601-2165]
synonym: "articular larua" EXACT [Wikipedia:Ligament]
synonym: "articular ligament" EXACT [Wikipedia:Ligament]
synonym: "ligament" BROAD [VSAO:0000072, ZFA:0001675]
synonym: "true ligament" EXACT [Wikipedia:Ligament]
xref: AAO:0010444
xref: AEO:0000090
xref: CALOHA:TS-2146
xref: EHDAA2:0003232
xref: EV:0100144
xref: FMA:25624
xref: GAID:118
xref: MA:0003005
xref: SCTID:410744003
xref: VSAO:0000072
xref: Wikipedia:Ligament#Articular_ligaments
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000211 ! ligament
intersection_of: UBERON:0000211 ! ligament
intersection_of: connects UBERON:0004765 ! skeletal element
intersection_of: part_of UBERON:0001434 ! skeletal system
relationship: composed_primarily_of UBERON:0007846 {source="VSAO"} ! dense regular connective tissue
relationship: connects UBERON:0004765 {notes="bones or cartilage organs"} ! skeletal element
relationship: has_part CL:0000057 {source="AEO"} ! fibroblast
relationship: has_part CL:0000327 {source="AEO"} ! extracellular matrix secreting cell
relationship: part_of UBERON:0001434 ! skeletal system
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/9/9a/Knee_diagram.svg" xsd:anyURI
property_value: editor_note "logical definition deliberately made strict to avoid classifying MA:spiral ligament as both nonskeletal and skeletal. see https://github.com/obophenotype/mouse-anatomy-ontology/issues/71" xsd:string
property_value: UBPROP:0000001 "Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000072", ontology="VSAO", source="PSPUB:0000170"}
property_value: UBPROP:0000001 "Ligament organ that primarily consists of regular dense connective tissue aggregated into fasciculi; connects bone and cartilage organs. Examples: sutural ligament, ligament of pinna, tarsal ligament[FMA:25624]." xsd:string {source="FMA:25624"}

[Term]
id: UBERON:0008851
name: ectoplacental cavity
namespace: uberon
def: "Closed space within the ectoplacental cone, formed by the fusion of the parts of the amniotic fold that separate it from the amniotic cavity[MP]. a developmental cavity that exists in some mammals and is derived by division of the proamniotic space; it is further removed from the embryo than the amniotic cavity in some mammals." [http://www.medilexicon.com/medicaldictionary.php?s=epamniotic+cavity, MP:0011207]
subset: pheno_slim
synonym: "epamniotic cavity" EXACT [http://www.medilexicon.com/medicaldictionary.php?s=epamniotic+cavity]
synonym: "epamniotic cavity" RELATED [MP:0011207]
xref: EMAPA:16080
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0004364 ! ectoplacental cone
relationship: luminal_space_of UBERON:0004364 ! ectoplacental cone
relationship: part_of UBERON:0004364 ! ectoplacental cone

[Term]
id: UBERON:0008856
name: stomach muscularis externa
namespace: uberon
def: "The smooth muscle layer of the stomach wall that functions to churn and mix food and gastric secretions as well as to move food along the digestive tract to the intestines." [MP:0010779]
subset: pheno_slim
synonym: "gastric muscularis" EXACT [FMA:14909]
synonym: "muscle layer of stomach" EXACT [FMA:14909]
synonym: "muscularis externa of stomach" EXACT [FMA:14909]
synonym: "tunica muscularis (gaster)" EXACT [FMA:14909]
synonym: "tunica muscularis gastris" EXACT []
xref: FMA:14909
xref: SCTID:362132003
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0018261 ! muscular coat of digestive tract
is_a: UBERON:0034933 ! layer of smooth muscle tissue
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0001167 ! wall of stomach
relationship: contributes_to_morphology_of UBERON:0001135 ! smooth muscle tissue
relationship: contributes_to_morphology_of UBERON:0001167 ! wall of stomach
relationship: part_of UBERON:0004222 {source="MA-abduced"} ! stomach smooth muscle
property_value: UBPROP:0000010 "the muscularis externa in the stomach differs from that of other GI organs in that it has three layers of smooth muscle instead of two" xsd:string {source="WP"}

[Term]
id: UBERON:0008858
name: pyloric canal
namespace: uberon
def: "The short narrow part of the stomach extending from the pyloric antrum to the pyloric sphincter." [MP:0010791, Wikipedia:Pyloric_canal]
subset: pheno_slim
synonym: "canalis pyloricus" EXACT [Wikipedia:Pyloric_canal]
synonym: "canalis pyloricus" RELATED OMO:0003011 [Wikipedia:Pyloric_canal]
xref: EMAPA:37944 {source="MA:th"}
xref: FMA:14580
xref: SCTID:245417002
xref: Wikipedia:Pyloric_canal
is_a: UBERON:0009870 {source="FMA"} ! zone of stomach
relationship: continuous_with UBERON:0001165 ! pyloric antrum
relationship: continuous_with UBERON:0001202 ! pyloric sphincter
relationship: contributes_to_morphology_of UBERON:0001166 ! pylorus
relationship: part_of UBERON:0001166 {source="Wikipedia"} ! pylorus
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/3/33/Illu_stomach.jpg" xsd:anyURI

[Term]
id: UBERON:0008861
name: pyloric gastric gland
namespace: uberon
def: "The gastric glands in the pyloric region of the stomach; the pyloric glands secrete mucin, which coats the stomach and protects it, and hormones such as gastrin and enkephalin[MP]." [MP:0010797, Wikipedia:Pyloric_gland]
subset: pheno_slim
synonym: "glandula pylorica" EXACT [FMA:14922]
synonym: "pyloric antrum gland" EXACT [OBOL:automatic]
synonym: "pyloric gland" EXACT [FMA:14922]
synonym: "pyloric mucuous gland" EXACT []
xref: EMAPA:27211
xref: FMA:14922
xref: NCIT:C33431
xref: SCTID:70710007
xref: UMLS:C0227239 {source="ncithesaurus:Pyloric_Gland"}
xref: Wikipedia:Pyloric_gland
is_a: UBERON:0000325 ! gastric gland
is_a: UBERON:0000414 {source="MP"} ! mucous gland
intersection_of: UBERON:0000325 ! gastric gland
intersection_of: part_of UBERON:0001166 ! pylorus
relationship: contributes_to_morphology_of UBERON:0001166 ! pylorus
relationship: has_quality PATO:0002299 {source="Wikipedia:Tubular_gland"} ! tubular
relationship: part_of UBERON:0004998 ! mucosa of pylorus
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/bf/Gray1054.png" xsd:anyURI
property_value: editor_note "check relationship to pylorus vs antrum" xsd:string

[Term]
id: UBERON:0008876
name: hypodermis skeletal muscle layer
namespace: uberon
alt_id: UBERON:0010934
def: "Any skeletal muscle organ in the hypodermis / superficial fascia." [ISBN:0123813611, MP:0011157]
subset: pheno_slim
synonym: "hypodermal muscle layer" EXACT [MP:0011157]
synonym: "hypodermis muscle layer" EXACT [MP:0011157]
synonym: "panniculus carnosus" NARROW [MP:0011157]
synonym: "superficial fascia muscular layer" EXACT []
xref: EMAPA:18188
xref: MA:0003140
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0004253 ! skin muscle
is_a: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0002072 ! hypodermis
relationship: contributes_to_morphology_of UBERON:0001015 ! musculature
relationship: contributes_to_morphology_of UBERON:0002072 ! hypodermis
relationship: has_muscle_insertion UBERON:0002097 ! skin of body
relationship: located_in UBERON:0002190 {source="MP-def"} ! subcutaneous adipose tissue
relationship: part_of UBERON:0002072 ! hypodermis
property_value: editor_note "We follow MP and treat this as part of the hypodermis, although some sources may consider the hypodermis to be superficial to this" xsd:string

[Term]
id: UBERON:0008886
name: pulmonary vascular system
namespace: uberon
def: "The part of the cardiovascular system consisting of all pulmonary arteries and all pulmonary veins." [ISBN:0073040584, Wikipedia:Pulmonary_circulation]
subset: human_reference_atlas
synonym: "pulmonary circulatory system" EXACT [FMA:45621]
synonym: "pulmonary system" EXACT [ISBN:0073040584]
xref: FMA:45621
xref: Wikipedia:Pulmonary_circulation
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0007798 {source="Obol"} ! vascular system
relationship: has_part UBERON:0002012 ! pulmonary artery
relationship: has_part UBERON:0002016 ! pulmonary vein
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Subdivision of cardiovascular system which has as its parts the pulmonary arterial and venous tree organs.[FMA]" xsd:string {ontology="FMA", source="FMA:45621"}

[Term]
id: UBERON:0008887
name: rectal venous plexus
namespace: uberon
def: "The hemorrhoidal plexus (or rectal venous plexus) surrounds the rectum, and communicates in front with the vesical venous plexus in the male, and the uterovaginal plexus in the female. A free communication between the portal and systemic venous systems is established through the hemorrhoidal plexus." [Wikipedia:Rectal_venous_plexus]
synonym: "haemorrhoidal plexus" RELATED [Wikipedia:Rectal_venous_plexus]
synonym: "hemorrhoidal plexus" RELATED [Wikipedia:Rectal_venous_plexus]
synonym: "plexus haemorrhoidalis" RELATED OMO:0003011 [Wikipedia:Rectal_venous_plexus]
synonym: "plexus venosus rectalis" RELATED OMO:0003011 [Wikipedia:Rectal_venous_plexus]
xref: FMA:18933
xref: NCIT:C32728
xref: SCTID:303051005
xref: UMLS:C0226766 {source="ncithesaurus:Hemorrhoidal_Plexus"}
xref: Wikipedia:Rectal_venous_plexus
is_a: UBERON:0001593 {source="FMA"} ! venous plexus
intersection_of: UBERON:0001593 ! venous plexus
intersection_of: surrounds UBERON:0001052 ! rectum
relationship: surrounds UBERON:0001052 ! rectum
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/69/Gray587.png" xsd:anyURI

[Term]
id: UBERON:0008895
name: splanchnocranium
namespace: uberon
def: "Subdivision of endoskeleton derived from pharyngeal arches." [https://orcid.org/0000-0002-6601-2165, ISBN:0073040584, Wikipedia:Facial_skeleton]
subset: human_reference_atlas
synonym: "branchial arch skeleton" RELATED []
synonym: "gill arch skeleton" RELATED []
synonym: "pharyngeal arch" RELATED INCONSISTENT [VSAO:0000149]
synonym: "pharyngeal arch skeleton" RELATED [ZFA:0001216]
synonym: "pharyngeal endoskeleton" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "pharyngeal skeleton" RELATED [ZFA:0001216]
synonym: "visceral cranium" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "visceral skeletal system" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "visceral skeleton" RELATED [UBERONREF:0000007]
synonym: "viscerocranium" EXACT INCONSISTENT [VHOG:0000315, Wikipedia:Viscerocranium, ZFA:0001216]
xref: AAO:0010157
xref: TAO:0001216
xref: VHOG:0000315
xref: VSAO:0000149
xref: Wikipedia:Facial_skeleton
xref: XAO:0003176
xref: ZFA:0001216
is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system
disjoint_from: UBERON:0011156 ! facial skeleton
relationship: develops_from UBERON:0002539 {source="https://github.com/obophenotype/uberon/issues/83"} ! pharyngeal arch
relationship: has_developmental_contribution_from UBERON:0003099 {notes="redundant", source="Grays", source="PMID:11237469"} ! cranial neural crest
relationship: overlaps UBERON:0011156 {gci_relation="part_of", gci_filler="NCBITaxon:89593"} ! facial skeleton
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium and consists of the jaws, hyoid and branchial arches.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001216", ontology="TAO", source="ZFIN:curator"}
property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium and consists of the jaws, hyoid, and branchial arches.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010157", ontology="AAO", source="AAO:EJS"}
property_value: UBPROP:0000001 "The part of the skull derived from the embryonic pharyngeal arches. [Biology_Online][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000315", ontology="VHOG", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000003 "The skull of ancestral tetrapods has the three basic components that we have been considering: (1) chondrocranium, (2) splanchnocranium, and (3) dermatocranium (reference 1); Each part of the skull arises from a separate phylogenetic source. The most ancient part is the splanchnocranium (visceral cranium), which first arose to support pharyngeal slits in protochordates (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000315", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.242, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.235", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000012 "many sources define this as the part of the endoskeletal that is from pharyngeal arches - this would make it part-disjoint from dermatocranium. However, there are many bones in AOs that have part-paths to both" xsd:string
property_value: UBPROP:0000012 "VSAO labels this term 'pharyngeal arch' (2012-06-01) - however, it clearly means pharyngeal arch skeleton." xsd:string {external_ontology="VSAO"}

[Term]
id: UBERON:0008907
name: dermal bone
namespace: uberon
def: "Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/267, VSAO:0000130]
synonym: "dermal bones" RELATED OMO:0003004 [ZFA:0001590]
xref: AAO:0010769
xref: TAO:0001590
xref: VSAO:0000130
xref: Wikipedia:Dermal_bone
xref: XAO:0004015
xref: ZFA:0001590
is_a: UBERON:0004756 {source="wd"} ! dermal skeletal element
is_a: UBERON:0007842 {source="VSAO"} ! membrane bone
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0010364 ! dermal skeleton
relationship: part_of UBERON:0010364 {source="VSAO"} ! dermal skeleton
property_value: UBPROP:0000001 "Intramembranous bone that forms superficially in the organism.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001590", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000012 "other AOs are not yet in sync with this classification" xsd:string

[Term]
id: UBERON:0008909
name: perichordal bone
namespace: uberon
def: "Bone element that is adjacent to the notochord." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000307]
synonym: "perichordal bone" RELATED [ZFA:0001629]
synonym: "perichordal bones" EXACT OMO:0003004 [ZFA:0001629]
xref: AAO:0010777
xref: TAO:0001639
xref: VSAO:0000307
xref: ZFA:0001629
is_a: UBERON:0012075 {notes="not in VSAO", source="ZFA"} ! replacement bone
intersection_of: UBERON:0001474 ! bone element
intersection_of: adjacent_to UBERON:0002328 ! notochord
relationship: adjacent_to UBERON:0002328 ! notochord
property_value: editor_note "We go with the latest VSAO in making this a subtype of bone, and add a logical definition based on the textual definition in VSAO. We also include the subtyping under 'replacement bone', for consistency with ZFA" xsd:string
property_value: UBPROP:0000001 "Replacement bone that forms within the connective tissue surrounding the notochord.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001639", ontology="TAO", source="TAO:wd"}

[Term]
id: UBERON:0008946
name: lung parenchyma
namespace: uberon
def: "A parenchyma that is part of a lung." [OBOL:automatic]
synonym: "parenchyma of lung" RELATED [BTO:0000763]
synonym: "pulmonary parenchyma" RELATED [EMAPA:35522]
synonym: "respiratory portion of lung" EXACT [FMA:27360]
xref: EMAPA:35522
xref: FMA:27360
xref: MA:0003168
xref: SCTID:201712001
is_a: UBERON:0000353 {source="FMA"} ! parenchyma
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000353 ! parenchyma
intersection_of: part_of UBERON:0002048 ! lung
relationship: part_of UBERON:0002048 {source="FMA"} ! lung

[Term]
id: UBERON:0008947
name: respiratory primordium
namespace: uberon
xref: EHDAA2:0004069
xref: NCIT:C34283
xref: UMLS:C1514898 {source="ncithesaurus:Respiratory_Primordium"}
is_a: UBERON:0001048 {source="Obol"} ! primordium
relationship: has_potential_to_develop_into UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0003258 ! endoderm of foregut

[Term]
id: UBERON:0008951
name: left lung lobe
namespace: uberon
def: "A lobe of lung that is part of a left lung." [OBOL:automatic]
synonym: "lobe of left lung" EXACT []
synonym: "lobe of the left lung" EXACT []
xref: EHDAA:2981
xref: NCIT:C48945
xref: SCTID:272655003
xref: UMLS:C1285107 {source="ncithesaurus:Lobe_of_the_Left_Lung"}
is_a: UBERON:0000101 ! lobe of lung
intersection_of: UBERON:0000101 ! lobe of lung
intersection_of: part_of UBERON:0002168 ! left lung
relationship: part_of UBERON:0002168 ! left lung
property_value: UBPROP:0000008 "1 in mice, divided into 2 in human by a single interlobar fissure, the oblqiue fissure" xsd:string {source="ISBN:0123813611"}

[Term]
id: UBERON:0008987
name: renal parenchyma
namespace: uberon
def: "The functional tissue of the kidney, consisting of the nephrons." [BTO:0003604]
synonym: "kidney parenchyma" RELATED [BTO:0003604]
synonym: "parenchyma of kidney" EXACT [FMA:15574]
xref: BTO:0003604
xref: FMA:15574
xref: SCTID:29704000
is_a: UBERON:0000353 {source="FMA"} ! parenchyma
intersection_of: UBERON:0000353 ! parenchyma
intersection_of: part_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0002113 {source="FMA"} ! kidney

[Term]
id: UBERON:0008989
name: submucosal esophageal gland
namespace: uberon
def: "One of the racemose glands in the walls of the esophagus that in humans are small and serve principally to lubricate the food but in some birds secrete a milky fluid on which the young are fed." [BTO:0003634, Wikipedia:Esophageal_glands]
synonym: "esophageal gland" EXACT [FMA:9404]
synonym: "glandulae oesophageae" EXACT [Wikipedia:Esophageal_glands]
synonym: "mucous gland of submucosa of esophagus" EXACT [FMA:9404]
synonym: "submocosal esophageal gland" RELATED []
xref: BTO:0003634
xref: FMA:9404
xref: NCIT:C32536
xref: SCTID:322749003
xref: UMLS:C0227178 {source="ncithesaurus:Esophageal_Gland"}
xref: Wikipedia:Esophageal_glands
is_a: UBERON:0003408 ! gland of digestive tract
is_a: UBERON:0005178 ! thoracic cavity element
is_a: UBERON:0011148 ! submucosal gland
intersection_of: UBERON:0011148 ! submucosal gland
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: located_in UBERON:0001972 ! submucosa of esophagus
relationship: part_of UBERON:0001043 ! esophagus
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e8/Illu_esophageal_layers.jpg" xsd:anyURI

[Term]
id: UBERON:0008998
name: vasculature of brain
namespace: uberon
alt_id: UBERON:0005284
def: "System pertaining to blood vessels in the brain." [BTO:0003840]
subset: efo_slim
synonym: "brain vasculature" EXACT []
synonym: "cerebrovascular system" EXACT [BTO:0003840]
synonym: "intracerebral vasculature" EXACT [FMA:61935]
xref: BTO:0003840
xref: EFO:0003491
xref: EMAPA:35186
xref: FMA:242007
xref: FMA:61935
xref: SCTID:362029003
xref: TAO:0000099
xref: ZFA:0000099
is_a: UBERON:0006876 ! vasculature of organ
is_a: UBERON:0036303 ! vasculature of central nervous system
relationship: part_of UBERON:0000955 ! brain

[Term]
id: UBERON:0009010
name: periurethral tissue
namespace: uberon
def: "Any portion of tissue that surrounds a urethra." [UBERON:cjm]
xref: BTO:0005081
xref: SCTID:256880003
is_a: UBERON:0000479 ! tissue
intersection_of: UBERON:0000479 ! tissue
intersection_of: surrounds UBERON:0000057 ! urethra
relationship: part_of UBERON:0001556 ! lower urinary tract
relationship: surrounds UBERON:0000057 ! urethra

[Term]
id: UBERON:0009015
name: upper back skin
namespace: uberon
def: "A zone of skin that is part of a dorsal thoracic segment of trunk." [OBOL:automatic]
xref: EMAPA:37280 {source="MA:th"}
xref: MA:0000510
xref: SCTID:304890003
is_a: UBERON:0001068 ! skin of back
is_a: UBERON:0001418 {source="MA"} ! skin of thorax
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0008231 ! dorsal thoracic segment of trunk
relationship: part_of UBERON:0008231 ! dorsal thoracic segment of trunk

[Term]
id: UBERON:0009027
name: vesical artery
namespace: uberon
def: "An artery that supplies blood to the urinary bladder." [http://orcid.org/0000-0002-6601-2165]
synonym: "arteria vesicali" EXACT OMO:0003011 []
synonym: "vesical arteries" EXACT OMO:0003004 []
xref: EMAPA:37131 {source="MA:th"}
xref: MA:0002078
xref: SCTID:244307000
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001255 ! urinary bladder
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0001255 ! urinary bladder

[Term]
id: UBERON:0009029
name: pudendal vein
namespace: uberon
def: "Either the internal or external pudendal vein, running from the genital-vulvar area and abdomen and down the leg." [http://orcid.org/0000-0002-6601-2165, https://veintreatmentcenter.com/vein-information/pudendal-veins/]
synonym: "pudic vein" RELATED []
synonym: "vena pudendae" EXACT OMO:0003011 [doi:10.1002/ca.23705]
synonym: "vena pudendales" EXACT OMO:0003011 [doi:10.1002/ca.23705]
xref: EMAPA:37184 {source="MA:th"}
xref: MA:0002202
xref: SCTID:395225000
is_a: UBERON:0001638 {source="MA"} ! vein
is_a: UBERON:0003520 ! pelvis blood vessel

[Term]
id: UBERON:0009030
name: left pulmonary vein
namespace: uberon
def: "Vein that drains left lung and returns blood to the heart." [http://orcid.org/0000-0002-6601-2165]
xref: EMAPA:37165 {source="MA:th"}
xref: MA:0002207
xref: NCIT:C48946
xref: SCTID:304057004
xref: UMLS:C0226670 {source="ncithesaurus:Left_Pulmonary_Vein"}
is_a: UBERON:0002016 ! pulmonary vein
intersection_of: UBERON:0002016 ! pulmonary vein
intersection_of: drains UBERON:0002168 ! left lung
relationship: drains UBERON:0002168 ! left lung
property_value: UBPROP:0000001 "A vein that returns oxygenated blood from the left lung to the left atrium of the heart[ncithesaurus:Left_Pulmonary_Vein]." xsd:string {source="ncithesaurus:Left_Pulmonary_Vein"}

[Term]
id: UBERON:0009032
name: right pulmonary vein
namespace: uberon
def: "Vein that drains right lung and returns blood to the heart." [http://orcid.org/0000-0002-6601-2165]
xref: EMAPA:37379 {source="MA:th"}
xref: MA:0002208
xref: NCIT:C48947
xref: SCTID:304056008
xref: UMLS:C0226669 {source="ncithesaurus:Right_Pulmonary_Vein"}
is_a: UBERON:0002016 ! pulmonary vein
intersection_of: UBERON:0002016 ! pulmonary vein
intersection_of: drains UBERON:0002167 ! right lung
relationship: drains UBERON:0002167 ! right lung
property_value: UBPROP:0000001 "A vein that returns oxygenated blood from the right lung to the left atrium of the heart[ncithesaurus:Right_Pulmonary_Vein]." xsd:string {source="ncithesaurus:Right_Pulmonary_Vein"}

[Term]
id: UBERON:0009097
name: gravid organism
namespace: uberon
def: "An organism containing a developing embryo, fetus, or unborn offspring within the body." [BTO:0004733]
synonym: "gravid" RELATED [BTO:0004733]
synonym: "pregnant adult" RELATED [BTO:0004733]
synonym: "pregnant adult stage" RELATED [BTO:0004733]
synonym: "pregnant organism" RELATED []
synonym: "pregnant stage" RELATED [BTO:0004733]
xref: BTO:0004733
xref: IDOMAL:0000443 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
is_a: UBERON:0007023 ! adult organism
intersection_of: UBERON:0007023 ! adult organism
intersection_of: has_part UBERON:0000922 ! embryo
relationship: has_part UBERON:0000922 ! embryo
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa
relationship: participates_in GO:0007565 ! female pregnancy

[Term]
id: UBERON:0009098
name: gravid uterus
namespace: uberon
def: "The uterus in pregnancy." [http://medical-dictionary.thefreedictionary.com/gravid+uterus]
synonym: "womb" RELATED []
xref: NCIT:C12406
xref: ncithesaurus:Gravid_Uterus
xref: SCTID:362253003
xref: UMLS:C1514389 {source="ncithesaurus:Pregnant_Uterus"}
is_a: UBERON:0000995 ! uterus
intersection_of: UBERON:0000995 ! uterus
intersection_of: location_of UBERON:0000922 ! embryo
relationship: contains_process GO:0007565 ! female pregnancy
relationship: location_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0009097 ! gravid organism

[Term]
id: UBERON:0009117
name: indifferent gonad
namespace: uberon
def: "A gonad prior to differentiating into a definitive testis or ovary." [http://www.medterms.com/script/main/art.asp?articlekey=8981]
comment: typically part of the embryo - however, in male tammar wallabies the gonads are indifferent at the neonatal stage[8827321]
subset: organ_slim
synonym: "gonad rudiment" RELATED []
xref: EHDAA2:0000716
xref: NCIT:C34192
xref: UMLS:C1512703 {source="ncithesaurus:Indifferent_Gonad"}
is_a: UBERON:0000991 ! gonad
relationship: part_of UBERON:0009196 ! indifferent external genitalia

[Term]
id: UBERON:0009127
name: epibranchial ganglion
namespace: uberon
def: "Cranial ganglion which develops from an epibranchial placode." [PMID:20133851, ZFIN:curator]
comment: Epibranchial ganglia orchestrate the development of the cranial neurogenic crest
synonym: "epibranchial ganglia" EXACT OMO:0003004 [ZFA:0001555]
xref: BTO:0006250 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: TAO:0001555
xref: ZFA:0001555
is_a: UBERON:0001714 {source="ZFA"} ! cranial ganglion
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0001714 ! cranial ganglion
intersection_of: develops_from UBERON:0003078 ! epibranchial placode
relationship: develops_from UBERON:0003078 {source="NCBIBook:NBK53175"} ! epibranchial placode

[Term]
id: UBERON:0009129
name: right atrium endocardium
namespace: uberon
def: "Endocardium that is part of the right atrium." [http://orcid.org/0000-0002-6601-2165]
synonym: "endocardium of right atrium" EXACT [FMA:7281]
synonym: "right atrial endocardium" EXACT [FMA:7281]
synonym: "right atrium endocardial tissue" RELATED [VHOG:0001228]
xref: EHDAA2:0000274
xref: FMA:7281
xref: NCIT:C102339
xref: SCTID:3194006
xref: VHOG:0001228
is_a: UBERON:0000487 ! simple squamous epithelium
is_a: UBERON:0002166 ! endocardium of atrium
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0002165 ! endocardium
intersection_of: part_of UBERON:0002078 ! right cardiac atrium
relationship: develops_from UBERON:0005092 {source="EHDAA2"} ! right horn of sinus venosus
relationship: part_of UBERON:0002078 ! right cardiac atrium
relationship: part_of UBERON:0006218 {source="EHDAA2"} ! common atrial chamber

[Term]
id: UBERON:0009133
name: pleuroperitoneal membrane
namespace: uberon
alt_id: UBERON:0009146
def: "A fold of tissue which extends into the peritoneal cavity of the developing embryo and participates in the separation of the pleural and peritoneal cavities." [http://medical-dictionary.thefreedictionary.com/pleuroperitoneal+membrane, Wikipedia:Pleuroperitoneal]
synonym: "pleuroperitoneal fold" EXACT [VHOG:0000757]
synonym: "pleuroperitoneal membranes" EXACT OMO:0003004 [EHDAA2:0001483]
xref: EHDAA2:0001483
xref: EMAPA:17709
xref: NCIT:C34256
xref: SCTID:361429005
xref: UMLS:C1283968 {source="ncithesaurus:Pleuroperitoneal_Membrane"}
xref: VHOG:0000757
xref: Wikipedia:Pleuroperitoneal
is_a: UBERON:0002050 {source="EHDAA2"} ! embryonic structure
is_a: UBERON:0005291 ! embryonic tissue
relationship: adjacent_to UBERON:0001179 ! peritoneal cavity
relationship: adjacent_to UBERON:0002402 ! pleural cavity
property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart [of other tetrapods] is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes). Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000757", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0009141
name: craniocervical region vein
namespace: uberon
def: "A vein that is part of a craniocervical region." [OBOL:automatic]
synonym: "craniocervical vein" EXACT []
synonym: "head and neck veins" EXACT [EHDAA2:0004542]
synonym: "vein of head and neck" EXACT []
xref: EHDAA2:0004542
xref: SCTID:32945007
is_a: UBERON:0013140 ! systemic vein
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0007811 ! craniocervical region
relationship: part_of UBERON:0007811 ! craniocervical region

[Term]
id: UBERON:0009142
name: entire embryonic mesenchyme
namespace: uberon
alt_id: UBERON:0003313
def: "Sum total of mesenchyme in the embryo." [https://github.com/obophenotype/human-developmental-anatomy-ontology/issues/7]
xref: EHDAA2:0001113
xref: EHDAA:177
xref: EMAPA:16097
is_a: UBERON:0000477 ! anatomical cluster
relationship: composed_primarily_of UBERON:0003104 ! mesenchyme
relationship: has_developmental_contribution_from UBERON:0000926 {source="EHDAA2"} ! mesoderm
relationship: part_of UBERON:0000922 ! embryo
property_value: editor_note "consider adding new class (EMAPA:16097) for mesenchyme of embryo (some mesenchyme is extraembryonic - e.g. amnion mesoderm)" xsd:string

[Term]
id: UBERON:0009145
name: pharyngeal region of foregut
namespace: uberon
synonym: "pharyngeal region" EXACT [EMAPA:16549]
xref: EMAPA:16549
xref: RETIRED_EHDAA2:0001454
is_a: UBERON:0005423 ! developing anatomical structure
relationship: part_of UBERON:0001041 {source="EHDAA2"} ! foregut

[Term]
id: UBERON:0009191
name: sphenoid bone pre-cartilage condensation
namespace: uberon
def: "A sphenoid endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic]
xref: EHDAA2:0003446
xref: EMAPA:18015
is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure
is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation
is_a: UBERON:0009891 ! facial mesenchyme
is_a: UBERON:0014387 ! mesenchyme derived from neural crest
is_a: UBERON:0015060 ! sphenoid endochondral element
intersection_of: UBERON:0015060 ! sphenoid endochondral element
intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation
relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0001703 {source="EHDAA2"} ! neurocranium
relationship: part_of UBERON:0002241 {source="EHDAA2"} ! chondrocranium

[Term]
id: UBERON:0009193
name: sphenoid cartilage element
namespace: uberon
def: "A sphenoid endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic]
synonym: "sphenoid bone cartilage condensation" EXACT [EHDAA2:0001888]
xref: EHDAA2:0001888
is_a: UBERON:0003932 ! cartilage element of chondrocranium
is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation
is_a: UBERON:0009891 ! facial mesenchyme
is_a: UBERON:0014387 ! mesenchyme derived from neural crest
is_a: UBERON:0015060 ! sphenoid endochondral element
intersection_of: UBERON:0015060 ! sphenoid endochondral element
intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue
relationship: develops_from UBERON:0009191 ! sphenoid bone pre-cartilage condensation

[Term]
id: UBERON:0009196
name: indifferent external genitalia
namespace: uberon
subset: organ_slim
xref: EHDAA2:0004021
is_a: UBERON:0004176 {source="cjm"} ! external genitalia
relationship: part_of UBERON:0000922 ! embryo

[Term]
id: UBERON:0009201
name: nephric duct
namespace: uberon
def: "A nephric duct is a tube that drains a primitive kidney[GO]." [GO:0072176]
comment: pronephric duct or mesonephric duct
xref: EMAPA:16577
xref: Wikipedia:Wolffian_duct
is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube
is_a: UBERON:0004819 ! kidney epithelium
is_a: UBERON:0006553 ! renal duct
is_a: UBERON:0006555 ! excretory tube
union_of: UBERON:0003060 ! pronephric duct
union_of: UBERON:0003074 ! mesonephric duct

[Term]
id: UBERON:0009204
name: medial nasal process mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a medial nasal prominence." [OBOL:automatic]
xref: EHDAA2:0001077
xref: EMAPA:16810
xref: FMA:312659
is_a: UBERON:0009501 ! mesenchyme of fronto-nasal process
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0004068 ! medial nasal prominence
relationship: part_of UBERON:0004068 {source="EHDAA2"} ! medial nasal prominence

[Term]
id: UBERON:0009292
name: embryonic nasal process
namespace: uberon
synonym: "nasal placode" RELATED []
xref: EHDAA2:0000581
xref: EHDAA:4776
xref: EMAPA:16680
xref: FMA:293971
xref: SCTID:308881001
is_a: UBERON:0012314 ! embryonic facial prominence
property_value: UBPROP:0000012 "medial or lateral; in EHDAA2 also frontonasal or intermaxillary" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0009479
name: ectoderm of buccopharyngeal membrane
namespace: uberon
def: "An ectoderm that is part of a buccopharyngeal membrane." [OBOL:automatic]
subset: emapa_ehdaa2
xref: EHDAA2:0000190
xref: EMAPA:16260
is_a: UBERON:0000924 ! ectoderm
intersection_of: UBERON:0000924 ! ectoderm
intersection_of: part_of UBERON:0006211 ! buccopharyngeal membrane
relationship: part_of UBERON:0006211 ! buccopharyngeal membrane

[Term]
id: UBERON:0009480
name: endoderm of buccopharyngeal membrane
namespace: uberon
def: "An endoderm that is part of a buccopharyngeal membrane." [OBOL:automatic]
subset: emapa_ehdaa2
xref: EHDAA2:0000191
xref: EMAPA:16261
is_a: UBERON:0000925 ! endoderm
intersection_of: UBERON:0000925 ! endoderm
intersection_of: part_of UBERON:0006211 ! buccopharyngeal membrane
relationship: part_of UBERON:0006211 ! buccopharyngeal membrane

[Term]
id: UBERON:0009482
name: associated mesenchyme of foregut-midgut junction
namespace: uberon
def: "Mesenchyme that is part of a foregut-midgut junction." [OBOL:automatic]
subset: emapa_ehdaa2
xref: EHDAA2:0000570
xref: EMAPA:16364
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0006235 ! foregut-midgut junction
relationship: part_of UBERON:0006235 ! foregut-midgut junction

[Term]
id: UBERON:0009483
name: mesentery of foregut-midgut junction
namespace: uberon
def: "A mesentery that is part of a foregut-midgut junction." [OBOL:automatic]
subset: emapa_ehdaa2
synonym: "foregut-midgut junction mesentery" EXACT [VHOG:0000430]
xref: EHDAA2:0000575
xref: EMAPA:16365
xref: VHOG:0000430
is_a: UBERON:0002095 ! mesentery
intersection_of: UBERON:0002095 ! mesentery
intersection_of: part_of UBERON:0006235 ! foregut-midgut junction
relationship: part_of UBERON:0006235 ! foregut-midgut junction
property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000430", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0009494
name: pharyngeal arch mesenchymal region
namespace: uberon
def: "A portion of mesenchymal tissue associated with an individual pharyngeal arch." [https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "branchial arch mesenchyme" EXACT [MP:0011262]
synonym: "pharyngeal arch mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: EMAPA:32755
xref: FMA:295694
is_a: UBERON:0005253 ! head mesenchyme
is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0002539 ! pharyngeal arch
relationship: has_developmental_contribution_from UBERON:0003099 {source="cjm"} ! cranial neural crest
relationship: part_of UBERON:0002539 ! pharyngeal arch
relationship: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme
property_value: editor_note "this represents a part of the entire arch mesenchyme (UBERON:0010046), and is therefore a superclass of the individual arch mesenchyme classes. Alternate definition: primordial embryonic connective tissue associated with the branchial arches, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to facial and cranial nerve-associated structures." xsd:string {source="MP:0011262"}

[Term]
id: UBERON:0009497
name: epithelium of foregut-midgut junction
namespace: uberon
def: "An epithelium that is part of a foregut-midgut junction." [OBOL:automatic]
subset: emapa_ehdaa2
xref: EHDAA2:0000573
xref: EMAPA:16564
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0003929 ! digestive tract epithelium
is_a: UBERON:0005911 ! endo-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0006235 ! foregut-midgut junction
relationship: develops_from UBERON:0009550 {source="EHDAA2"} ! endoderm of foregut-midgut junction
relationship: part_of UBERON:0003929 {source="EHDAA2"} ! digestive tract epithelium
relationship: part_of UBERON:0006235 ! foregut-midgut junction

[Term]
id: UBERON:0009501
name: mesenchyme of fronto-nasal process
namespace: uberon
def: "The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the frontonasal region of the head." [MP:0011266]
subset: emapa_ehdaa2
subset: pheno_slim
synonym: "frontonasal mesenchyme" EXACT [MP:0011266]
synonym: "naso-frontal mesenchyme" EXACT [MP:0011266]
xref: EHDAA2:0004109
xref: EMAPA:16683
xref: FMA:295821
is_a: UBERON:0007213 ! mesenchyme derived from head neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0004066 ! frontonasal prominence
relationship: develops_from UBERON:0007213 ! mesenchyme derived from head neural crest
relationship: part_of UBERON:0004066 ! frontonasal prominence

[Term]
id: UBERON:0009503
name: mesenchyme of hindgut
namespace: uberon
def: "Mesenchyme that is part of a developing hindgut." [OBOL:automatic]
subset: emapa_ehdaa2
synonym: "hindgut associated mesenchyme" EXACT [EHDAA2:0000780]
xref: EHDAA2:0000780
xref: EMAPA:16716
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0001046 ! hindgut
relationship: part_of UBERON:0001046 ! hindgut

[Term]
id: UBERON:0009521
name: anal membrane endodermal component
namespace: uberon
def: "An endoderm that is part of a anal region." [OBOL:automatic]
subset: emapa_ehdaa2
xref: EHDAA2:0004020
xref: EMAPA:17177
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0005911 ! endo-epithelium
intersection_of: UBERON:0000490 ! unilaminar epithelium
intersection_of: develops_from UBERON:0000925 ! endoderm
intersection_of: part_of UBERON:0001353 ! anal region
relationship: part_of UBERON:0001353 ! anal region

[Term]
id: UBERON:0009526
name: maxillary process mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a maxillary prominence." [OBOL:automatic]
subset: emapa_ehdaa2
synonym: "mesenchyme of maxillary process" EXACT [EMAPA:17361]
synonym: "mesenchyme of maxillary prominence" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: EHDAA2:0001071
xref: EMAPA:17361
xref: FMA:312691
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0005291 ! embryonic tissue
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0005868 ! maxillary prominence
relationship: part_of UBERON:0005868 ! maxillary prominence

[Term]
id: UBERON:0009536
name: vascular element of left lung
namespace: uberon
def: "A vascular plexus that is part of a left lung." [OBOL:automatic]
subset: emapa_ehdaa2
xref: EHDAA2:0000963
xref: EMAPA:17660
is_a: UBERON:0000102 ! lung vasculature
is_a: UBERON:0005629 ! vascular plexus
intersection_of: UBERON:0005629 ! vascular plexus
intersection_of: part_of UBERON:0002168 ! left lung
relationship: part_of UBERON:0002168 ! left lung

[Term]
id: UBERON:0009537
name: vascular element of right lung
namespace: uberon
def: "A vascular plexus that is part of a right lung." [OBOL:automatic]
subset: emapa_ehdaa2
xref: EHDAA2:0001757
xref: EMAPA:17668
is_a: UBERON:0000102 ! lung vasculature
is_a: UBERON:0005629 ! vascular plexus
intersection_of: UBERON:0005629 ! vascular plexus
intersection_of: part_of UBERON:0002167 ! right lung
relationship: part_of UBERON:0002167 ! right lung

[Term]
id: UBERON:0009548
name: hepatic sinusoid of left of lobe of liver
namespace: uberon
def: "A hepatic sinusoid that is part of a left lobe of liver." [OBOL:automatic]
subset: emapa_ehdaa2
synonym: "left lobe hepatic sinusoids" EXACT [VHOG:0000709]
xref: EHDAA2:0001001
xref: EMAPA:18309
xref: VHOG:0000709
is_a: UBERON:0001281 ! hepatic sinusoid
intersection_of: UBERON:0001281 ! hepatic sinusoid
intersection_of: part_of UBERON:0001115 ! left lobe of liver
relationship: develops_in UBERON:0001115 ! left lobe of liver
relationship: part_of UBERON:0001115 ! left lobe of liver

[Term]
id: UBERON:0009549
name: hepatic sinusoid of right of lobe of liver
namespace: uberon
def: "A hepatic sinusoid that is part of a right lobe of liver." [OBOL:automatic]
subset: emapa_ehdaa2
synonym: "right lobe hepatic sinusoids" EXACT [VHOG:0000710]
xref: EHDAA2:0001009
xref: EMAPA:18316
xref: VHOG:0000710
is_a: UBERON:0001281 ! hepatic sinusoid
intersection_of: UBERON:0001281 ! hepatic sinusoid
intersection_of: part_of UBERON:0001114 ! right lobe of liver
relationship: develops_in UBERON:0001114 ! right lobe of liver
relationship: part_of UBERON:0001114 ! right lobe of liver

[Term]
id: UBERON:0009550
name: endoderm of foregut-midgut junction
namespace: uberon
def: "An endoderm that is part of a foregut-midgut junction." [OBOL:automatic]
subset: emapa_ehdaa2
xref: EHDAA2:0000572
xref: EMAPA:18403
is_a: UBERON:0000925 ! endoderm
intersection_of: UBERON:0000925 ! endoderm
intersection_of: part_of UBERON:0006235 ! foregut-midgut junction
relationship: part_of UBERON:0006235 ! foregut-midgut junction

[Term]
id: UBERON:0009566
name: intestinal submucosa
namespace: uberon
def: "A submucosa that is part of a intestine." [OBOL:automatic]
synonym: "submucosa of intestine" EXACT [FMA:15696]
xref: FMA:15696
is_a: UBERON:0018257 ! submucosa of digestive tract
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0001262 {source="FMA"} ! wall of intestine

[Term]
id: UBERON:0009568
name: trunk region of vertebral column
namespace: uberon
def: "Subdivision of vertebral column that corresponds to the trunk of the body, containing the trunk/presacral vertebrae. In organisms that have a thoracic and lumbar distinction, this corresponds to the sum of both of these regions." [UBERONREF:0000006]
subset: pheno_slim
synonym: "presacral region" RELATED [AAO:0000612]
synonym: "thoracolumbar column" EXACT []
synonym: "thoracolumbar region" RELATED [AAO:0000612]
synonym: "thoracolumbar region of vertebral column" EXACT []
synonym: "thoracolumbar vertebrae set" EXACT [FMA:72066]
synonym: "thoracolumbar vertebral column" EXACT []
synonym: "trunk region" RELATED [AAO:0000612]
synonym: "trunk skeleton" RELATED []
synonym: "trunk spine" RELATED []
synonym: "trunk vertebrae series" EXACT []
synonym: "trunk vertebral column" EXACT []
xref: AAO:0000612
xref: FMA:72066
xref: NCIT:C92597
xref: SCTID:281699004
is_a: UBERON:0006077 ! subdivision of vertebral column
intersection_of: UBERON:0006077 ! subdivision of vertebral column
intersection_of: part_of UBERON:0002100 ! trunk
intersection_of: subdivision_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk
relationship: subdivision_of UBERON:0002100 ! trunk
property_value: UBPROP:0000001 "Region of the vertebral column between the atlas and the sacrum consisting of seven to 285 vertebrae.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000612", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"}

[Term]
id: UBERON:0009569
name: subdivision of trunk
namespace: uberon
subset: non_informative
synonym: "region of trunk" EXACT [FMA:25054]
synonym: "trunk subdivision" EXACT [FMA:25054]
xref: FMA:25054
xref: SCTID:22943007
is_a: UBERON:0000475 ! organism subdivision
relationship: part_of UBERON:0002100 ! trunk

[Term]
id: UBERON:0009570
name: spinal cord sulcus limitans
namespace: uberon
def: "A sulcus limitans of neural tube that is part of a future spinal cord." [OBOL:automatic]
synonym: "spinal cord lateral wall sulcus limitans" EXACT [EHDAA2:0001265]
xref: EHDAA2:0001265
xref: EMAPA:17584
xref: VHOG:0001548
is_a: UBERON:0005478 ! sulcus limitans of neural tube
intersection_of: UBERON:0005478 ! sulcus limitans of neural tube
intersection_of: part_of UBERON:0006241 ! future spinal cord
relationship: part_of UBERON:0006241 ! future spinal cord

[Term]
id: UBERON:0009576
name: medulla oblongata sulcus limitans
namespace: uberon
def: "A sulcus limitans of neural tube that is part of a future medulla oblongata." [OBOL:automatic]
xref: EHDAA2:0001100
xref: EMAPA:17561
is_a: UBERON:0005478 ! sulcus limitans of neural tube
intersection_of: UBERON:0005478 ! sulcus limitans of neural tube
intersection_of: part_of UBERON:0001896 ! medulla oblongata
relationship: develops_from UBERON:0009578 {source="EHDAA2"} ! myelencephalon sulcus limitans
relationship: part_of UBERON:0001896 ! medulla oblongata

[Term]
id: UBERON:0009577
name: metencephalon sulcus limitans
namespace: uberon
def: "A sulcus limitans of neural tube that is part of a future metencephalon." [OBOL:automatic]
xref: EHDAA2:0001161
xref: EMAPA:17567
is_a: UBERON:0005478 ! sulcus limitans of neural tube
intersection_of: UBERON:0005478 ! sulcus limitans of neural tube
intersection_of: part_of UBERON:0010092 ! future metencephalon
relationship: part_of UBERON:0010092 ! future metencephalon

[Term]
id: UBERON:0009578
name: myelencephalon sulcus limitans
namespace: uberon
def: "A sulcus limitans of neural tube that is part of a future myelencephalon." [OBOL:automatic]
xref: EHDAA2:0001945
is_a: UBERON:0005478 ! sulcus limitans of neural tube
intersection_of: UBERON:0005478 ! sulcus limitans of neural tube
intersection_of: part_of UBERON:0010096 ! future myelencephalon
relationship: part_of UBERON:0010096 ! future myelencephalon

[Term]
id: UBERON:0009581
name: midbrain mantle layer
namespace: uberon
synonym: "mantle layer lateral wall mesencephalon" RELATED [VHOG:0000910]
synonym: "mantle layer lateral wall midbrain" EXACT [VHOG:0000910]
synonym: "midbrain lateral wall mantle layer" EXACT []
xref: EHDAA2:0001172
xref: EMAPA:16977
xref: VHOG:0000910
is_a: UBERON:0004061 ! neural tube mantle layer
intersection_of: UBERON:0004061 ! neural tube mantle layer
intersection_of: part_of UBERON:0009616 ! presumptive midbrain
relationship: part_of UBERON:0009616 ! presumptive midbrain

[Term]
id: UBERON:0009583
name: spinal cord mantle layer
namespace: uberon
synonym: "mantle layer lateral wall spinal cord" EXACT [VHOG:0000911]
synonym: "spinal cord lateral wall mantle layer" EXACT []
xref: EMAPA:17580
xref: VHOG:0000911
is_a: UBERON:0004061 ! neural tube mantle layer
intersection_of: UBERON:0004061 ! neural tube mantle layer
intersection_of: part_of UBERON:0006241 ! future spinal cord
relationship: part_of UBERON:0006241 ! future spinal cord

[Term]
id: UBERON:0009584
name: 1st arch mandibular mesenchyme
namespace: uberon
alt_id: UBERON:0010043
def: "Mesenchyme that is part of a 1st arch mandibular component." [OBOL:automatic]
synonym: "mandibular component mesenchyme" RELATED []
synonym: "mandibular mesenchyme" RELATED []
synonym: "mesenchymal region of mandibular component of first pharyngeal arch" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "mesenchyme of mandibular component" EXACT [EMAPA:16385]
xref: EHDAA2:0000034
xref: EMAPA:16385
is_a: UBERON:0010042 ! 1st arch mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0007237 ! 1st arch mandibular component
relationship: part_of UBERON:0007237 {source="EMAPA"} ! 1st arch mandibular component

[Term]
id: UBERON:0009602
name: left lung associated mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a developing left lung." [OBOL:automatic]
synonym: "left lung mesenchyme" EXACT [EMAPA:17654]
xref: EHDAA2:0000944
xref: EMAPA:16730
xref: EMAPA:17654
is_a: UBERON:0004883 ! lung mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0002168 ! left lung
relationship: part_of UBERON:0002168 ! left lung

[Term]
id: UBERON:0009603
name: right lung associated mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a developing right lung." [OBOL:automatic]
synonym: "right lung mesenchyme" EXACT [EMAPA:17662]
xref: EHDAA2:0001739
xref: EMAPA:17662
is_a: UBERON:0004883 ! lung mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0002167 ! right lung
relationship: part_of UBERON:0002167 ! right lung

[Term]
id: UBERON:0009611
name: midbrain neural plate
namespace: uberon
def: "A neural plate that develops_from a presumptive midbrain." [OBOL:automatic]
xref: TAO:0007019
xref: ZFA:0007019
is_a: UBERON:0003075 ! neural plate
intersection_of: UBERON:0003075 {source="ZFA"} ! neural plate
intersection_of: develops_from UBERON:0009616 {source="ZFA"} ! presumptive midbrain
relationship: develops_from UBERON:0009616 ! presumptive midbrain
relationship: part_of UBERON:0003056 {source="ZFA"} ! pre-chordal neural plate

[Term]
id: UBERON:0009614
name: hindbrain neural plate
namespace: uberon
def: "A neural plate that develops_from a presumptive hindbrain." [OBOL:automatic]
xref: TAO:0007022
xref: ZFA:0007022
is_a: UBERON:0003075 ! neural plate
intersection_of: UBERON:0003075 {source="ZFA"} ! neural plate
intersection_of: develops_from UBERON:0007277 {source="ZFA"} ! presumptive hindbrain
relationship: develops_from UBERON:0007277 ! presumptive hindbrain
relationship: part_of UBERON:0003057 {source="ZFA"} ! chordal neural plate

[Term]
id: UBERON:0009615
name: midbrain hindbrain boundary neural plate
namespace: uberon
synonym: "MHB neural plate" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "midbrain-hindbrain boundary neural plate" EXACT [ZFA:0007044]
xref: TAO:0007044
xref: ZFA:0007044
is_a: UBERON:0006598 ! presumptive structure
relationship: develops_from UBERON:0007281 ! presumptive midbrain hindbrain boundary
relationship: immediate_transformation_of UBERON:0007281 {notes="https://github.com/obophenotype/uberon/issues/438", source="Bgee:AN"} ! presumptive midbrain hindbrain boundary
relationship: part_of UBERON:0003075 {source="ZFA"} ! neural plate
property_value: editor_note "TODO - developmental relationships for lines" xsd:string

[Term]
id: UBERON:0009616
name: presumptive midbrain
namespace: uberon
def: "A presumptive structure that has the potential to develop into a midbrain." [OBOL:automatic]
subset: efo_slim
synonym: "early midbrain" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "future midbrain" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "mesencephalon" RELATED [EHDAA2:0000615]
synonym: "presumptive mesencephalon" EXACT [ZFA:0000148]
xref: BAMS:MES
xref: EFO:0003432
xref: EHDAA2:0000615
xref: EMAPA:16140
xref: TAO:0000148
xref: Wikipedia:Mesencephalon
xref: ZFA:0000148
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0001891 ! midbrain
relationship: develops_from UBERON:0003080 ! anterior neural tube
relationship: develops_from UBERON:0010286 {source="ZFA"} ! midbrain neural tube
relationship: has_potential_to_develop_into UBERON:0001891 ! midbrain
relationship: part_of UBERON:0006238 {source="ZFA"} ! future brain
property_value: editor_note "TODO - unify naming conventions" xsd:string

[Term]
id: UBERON:0009617
name: head paraxial mesoderm
namespace: uberon
def: "Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles." [PMID:21610022]
synonym: "cephalic paraxial mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "cephalic paraxial mesoderm" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "cranial paraxial mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "cranial paraxial mesoderm" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "head paraxial mesenchyme" EXACT [EHDAA2:0000736, https://github.com/obophenotype/uberon/issues/30]
synonym: "somitomere" RELATED []
synonym: "somitomeric mesoderm" RELATED []
xref: EHDAA2:0000736
xref: EHDAA:364
xref: EMAPA:16171
is_a: UBERON:0005253 ! head mesenchyme
relationship: part_of UBERON:0003077 ! paraxial mesoderm
relationship: part_of UBERON:0005253 {source="EHDAA2"} ! head mesenchyme
property_value: UBPROP:0000011 "A major contributor to neurocranium [PMID:16313393]" xsd:string

[Term]
id: UBERON:0009618
name: trunk paraxial mesoderm
namespace: uberon
synonym: "trunk and cervical paraxial mesenchyme" EXACT [EHDAA2:0002094]
synonym: "trunk paraxial mesenchyme" RELATED [https://github.com/obophenotype/uberon/issues/30]
xref: EHDAA2:0002094
is_a: UBERON:0005256 ! trunk mesenchyme
relationship: part_of UBERON:0003077 ! paraxial mesoderm
relationship: part_of UBERON:0005256 {source="EHDAA2"} ! trunk mesenchyme

[Term]
id: UBERON:0009621
name: tail somite
namespace: uberon
def: "A somite that is part of a tail." [OBOL:automatic]
xref: AAO:0010383
xref: EMAPA:16860
xref: XAO:0003143
is_a: UBERON:0002329 ! somite
intersection_of: UBERON:0002329 ! somite
intersection_of: part_of UBERON:0002415 ! tail
relationship: part_of UBERON:0002415 ! tail

[Term]
id: UBERON:0009651
name: nephron tubule basement membrane
namespace: uberon
def: "A basement membrane that is part of a nephron tubule." [OBOL:automatic]
synonym: "kidney tubule basement membrane" EXACT [MA:0001680]
synonym: "renal tubular basement membrane" EXACT []
synonym: "renal tubule basement membrane" EXACT [MA:0001680]
xref: EMAPA:37490 {source="MA:th"}
xref: MA:0001680
xref: NCIT:C49273
xref: SCTID:245251000
xref: UMLS:C1709901 {source="ncithesaurus:Renal_Tubule_Basement_Membrane"}
is_a: UBERON:0005769 ! basement membrane of epithelium
intersection_of: UBERON:0005769 ! basement membrane of epithelium
intersection_of: part_of UBERON:0001231 ! nephron tubule
relationship: part_of UBERON:0004810 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! nephron tubule epithelium

[Term]
id: UBERON:0009657
name: artery of lip
namespace: uberon
synonym: "labial artery" BROAD [MA:0001987]
xref: EMAPA:37092 {source="MA:th"}
xref: MA:0001987
xref: NCIT:C52947
xref: UMLS:C1708633 {source="ncithesaurus:Labial_Artery"}
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001833 ! lip
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0001833 ! lip

[Term]
id: UBERON:0009661
name: midbrain nucleus
namespace: uberon
def: "Nucleus located in the midbrain." [ZFIN:curator]
xref: SCTID:279285003
xref: TAO:0002209
xref: ZFA:0001665
is_a: UBERON:0002308 ! nucleus of brain
intersection_of: UBERON:0002308 ! nucleus of brain
intersection_of: part_of UBERON:0001891 ! midbrain
relationship: part_of UBERON:0001891 ! midbrain

[Term]
id: UBERON:0009662
name: hindbrain nucleus
namespace: uberon
def: "Nucleus located within the hindbrain." [ZFIN:curator]
xref: TAO:0002177
xref: ZFA:0001658
is_a: UBERON:0002308 ! nucleus of brain
intersection_of: UBERON:0002308 ! nucleus of brain
intersection_of: part_of UBERON:0002028 ! hindbrain
relationship: part_of UBERON:0002028 ! hindbrain

[Term]
id: UBERON:0009664
name: gut mesentery
namespace: uberon
synonym: "peritoneal cavity mesentary" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "peritoneal mesentary" RELATED [http://orcid.org/0000-0002-6601-2165]
xref: EHDAA2:0004566
xref: EMAPA:32911
xref: MA:0003203
is_a: UBERON:0002095 ! mesentery
relationship: located_in UBERON:0001179 {source="EHDAA2"} ! peritoneal cavity
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/509" xsd:anyURI

[Term]
id: UBERON:0009669
name: embryonic cloacal lumen
namespace: uberon
def: "An anatomical space that surrounded_by a embryonic cloaca." [OBOL:automatic]
xref: EHDAA2:0004586
is_a: UBERON:0012463 ! cloacal lumen
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000163 ! embryonic cloaca
relationship: luminal_space_of UBERON:0000163 ! embryonic cloaca
relationship: part_of UBERON:0000163 ! embryonic cloaca
relationship: surrounded_by UBERON:0009846 ! embryonic cloacal epithelium

[Term]
id: UBERON:0009670
name: rectal lumen
namespace: uberon
def: "An anatomical space that surrounded_by a rectum." [OBOL:automatic]
synonym: "lumen of rectum" EXACT [FMA:14598]
xref: EHDAA2:0004587
xref: EMAPA:18388
xref: FMA:14598
xref: SCTID:259740004
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0001052 ! rectum
relationship: develops_from UBERON:0009669 {source="EHDAA2"} ! embryonic cloacal lumen
relationship: luminal_space_of UBERON:0001052 ! rectum
relationship: part_of UBERON:0001052 ! rectum
relationship: part_of UBERON:0012465 {source="cjm"} ! lumen of terminal part of digestive tract

[Term]
id: UBERON:0009708
name: dorsal pancreas
namespace: uberon
subset: human_reference_atlas
subset: organ_slim
synonym: "pancreatis dorsalis" RELATED []
xref: EHDAA2:0001371
is_a: UBERON:0002365 {source="EHDAA2"} ! exocrine gland
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0005177 ! trunk region element
relationship: develops_from UBERON:0010375 {source="EHDAA2"} ! pancreas dorsal primordium
relationship: has_developmental_contribution_from UBERON:0003923 {source="cjm"} ! dorsal pancreatic bud
relationship: part_of UBERON:0001264 {source="EHDAA2"} ! pancreas
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0009709
name: ventral pancreas
namespace: uberon
subset: human_reference_atlas
subset: organ_slim
synonym: "pancreatis ventralis" RELATED []
xref: EHDAA2:0001393
is_a: UBERON:0002365 {source="EHDAA2"} ! exocrine gland
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0005177 ! trunk region element
relationship: develops_from UBERON:0010376 {source="EHDAA2"} ! pancreas ventral primordium
relationship: has_developmental_contribution_from UBERON:0003924 {source="cjm"} ! ventral pancreatic bud
relationship: part_of UBERON:0001264 {source="EHDAA2"} ! pancreas
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0009712
name: endocardium of right ventricle
namespace: uberon
def: "Any endocardium that is part of the right ventricle of the heart." [http://orcid.org/0000-0002-6601-2165]
synonym: "endocardial lining of right ventricle" RELATED [EMAPA:17341]
synonym: "right ventricle endocardial tissue" RELATED [VHOG:0001235]
synonym: "right ventricle endocardium" EXACT [VHOG:0001235]
synonym: "right ventricular endocardium" EXACT [FMA:9536]
xref: EHDAA2:0002188
xref: EMAPA:17341
xref: FMA:9536
xref: NCIT:C102343
xref: SCTID:8911002
xref: VHOG:0001235
is_a: UBERON:0001081 ! endocardium of ventricle
intersection_of: UBERON:0001081 ! endocardium of ventricle
intersection_of: part_of UBERON:0002080 ! heart right ventricle
relationship: attaches_to UBERON:0006567 {source="FMA"} ! right ventricle myocardium
relationship: develops_from UBERON:0004706 {source="EHDAA2"} ! bulbus cordis
relationship: part_of UBERON:0002080 ! heart right ventricle
property_value: UBPROP:0000001 "Endocardium of ventricle which is continuous tricuspid valve, pulmonary valve and with the tunica intima of the pulmonary trunk." xsd:string {source="FMA:9536"}

[Term]
id: UBERON:0009713
name: endocardium of left ventricle
namespace: uberon
def: "Any endocardium that is part of the left ventricle of the heart." [http://orcid.org/0000-0002-6601-2165]
synonym: "endocardial lining of left ventricle" RELATED [EMAPA:17338]
synonym: "left ventricle endocardial tissue" RELATED [VHOG:0001233]
synonym: "left ventricle endocardium" EXACT [VHOG:0001233]
synonym: "left ventricular endocardium" EXACT [FMA:9559]
xref: EHDAA2:0002182
xref: EMAPA:17338
xref: FMA:9559
xref: SCTID:191004004
xref: VHOG:0001233
is_a: UBERON:0001081 ! endocardium of ventricle
intersection_of: UBERON:0001081 ! endocardium of ventricle
intersection_of: part_of UBERON:0002084 ! heart left ventricle
relationship: attaches_to UBERON:0006566 {source="FMA"} ! left ventricle myocardium
relationship: part_of UBERON:0002084 ! heart left ventricle
property_value: UBPROP:0000001 "Endocardium of ventricle which is continuous with mitral valve, aortic valve, atrioventricular septum and the tunica intima of the aorta." xsd:string {source="FMA:9559"}

[Term]
id: UBERON:0009715
name: stomodeal lumen
namespace: uberon
def: "An anatomical cavity that surrounded_by a stomodeum." [OBOL:automatic]
synonym: "lumen of stomatodaeum" EXACT []
synonym: "lumen of stomodeum" EXACT []
synonym: "stomatodeal cavity" EXACT []
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000930 ! stomodeum
relationship: luminal_space_of UBERON:0000930 ! stomodeum
relationship: part_of UBERON:0000930 ! stomodeum

[Term]
id: UBERON:0009722
name: entire pharyngeal arch endoderm
namespace: uberon
synonym: "pharyngeal arch endoderm" RELATED [EHDAA2:0004621]
xref: EHDAA2:0004621
xref: EMAPA:32754
xref: FMA:293087
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0005911 ! endo-epithelium
is_a: UBERON:0015833 ! foregut epithelium
relationship: part_of UBERON:0003929 {source="EHDAA2"} ! digestive tract epithelium
relationship: part_of UBERON:0008814 ! pharyngeal arch system

[Term]
id: UBERON:0009751
name: cardiac mesenchyme
namespace: uberon
def: "The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures." [MP:0011264]
subset: pheno_slim
synonym: "heart mesenchyme" EXACT [EMAPA:36438]
xref: EHDAA2:0004162
xref: EMAPA:36438
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart
property_value: editor_note "decide whether to merge with cardiac mesoderm. In EHDAA2 this lasts CS12->unbounded, includes mesenchyme of individual components as parts" xsd:string

[Term]
id: UBERON:0009752
name: pancreas mesenchyme
namespace: uberon
def: "The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing pancreas." [MP:0011265]
subset: efo_slim
subset: human_reference_atlas
subset: pheno_slim
xref: EFO:0002557
xref: EMAPA:26220
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0001264 ! pancreas
relationship: part_of UBERON:0001264 ! pancreas
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0009758
name: abdominal ganglion
namespace: uberon
def: "A ganglion that is part of a abdominal segment of trunk." [OBOL:automatic]
xref: SCTID:280508003
is_a: UBERON:0007134 ! trunk ganglion
intersection_of: UBERON:0000045 ! ganglion
intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk
relationship: part_of UBERON:0002417 ! abdominal segment of trunk

[Term]
id: UBERON:0009773
name: renal tubule
namespace: uberon
def: "A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [DOI:10.1371/journal.pone.0099864, GO:0061333, GOC:dph, GOC:mtg_kidney_jan10]
subset: grouping_class
subset: pheno_slim
synonym: "renal tubule (generic)" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "tubule of excretory system" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic]
is_a: UBERON:0003914 ! epithelial tube
is_a: UBERON:0006555 ! excretory tube
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
property_value: curator_notes "this class groups vertebrate nephron tubules with analagous structures such as insect Malpighian tubules" xsd:string

[Term]
id: UBERON:0009778
name: pleural sac
namespace: uberon
def: "A serous sac that has the pleura and the pleural cavity as parts." [https://github.com/obophenotype/uberon/issues/86]
subset: non_informative
xref: EHDAA2:0004737
xref: FMA:9690
xref: SCTID:361996004
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0005906 ! serous sac
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0005906 ! serous sac
intersection_of: has_part UBERON:0000977 ! pleura
intersection_of: has_part UBERON:0002402 ! pleural cavity
relationship: has_part UBERON:0000977 ! pleura
relationship: has_part UBERON:0002402 ! pleural cavity
relationship: in_lateral_side_of UBERON:0001004 {source="FMA-abduced-lr"} ! respiratory system
relationship: part_of UBERON:0001558 {source="FMA"} ! lower respiratory tract
property_value: UBPROP:0000012 "despite its name the class EHDAA2:0004737 is not a true cavity, it corresponds to what we call the sac" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0009842
name: glandular acinus
namespace: uberon
def: "The many-lobed berry cluster of cells that is the terminous of a gland where the secretion is produced is acinar in form." [Wikipedia:Acinus]
synonym: "acini" RELATED OMO:0003004 [Wikipedia:Acinus]
synonym: "acinus" BROAD [FMA:55588]
xref: FMA:55588
xref: Wikipedia:Acinus
is_a: UBERON:0034922 ! cell cluster
intersection_of: UBERON:0034922 ! cell cluster
intersection_of: has_part CL:0000151 ! secretory cell
intersection_of: has_quality PATO:0002422 ! acinar
intersection_of: part_of UBERON:0002530 ! gland
relationship: has_part CL:0000151 ! secretory cell
relationship: has_quality PATO:0002422 ! acinar
relationship: part_of UBERON:0002530 ! gland
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png" xsd:anyURI
property_value: UBPROP:0000007 "acinar" xsd:string

[Term]
id: UBERON:0009844
name: urogenital sinus lumen
namespace: uberon
def: "An anatomical space that surrounded_by a primitive urogenital sinus." [OBOL:automatic]
xref: EHDAA2:0002142
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000164 ! primitive urogenital sinus
relationship: develops_from UBERON:0009669 {source="EHDAA2"} ! embryonic cloacal lumen
relationship: luminal_space_of UBERON:0000164 ! primitive urogenital sinus
relationship: part_of UBERON:0000164 ! primitive urogenital sinus
relationship: surrounded_by UBERON:0004902 ! urogenital sinus epithelium

[Term]
id: UBERON:0009845
name: urogenital sinus mesenchyme
namespace: uberon
def: "Mesenchyme that surrounds primitive urogenital sinus." [OBOL:automatic]
synonym: "UGM" EXACT OMO:0003000 [PMID:18977204]
xref: EMAPA:31500
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 {source="PMID:18977204"} ! mesenchyme
intersection_of: surrounds UBERON:0000164 {source="PMID:18977204"} ! primitive urogenital sinus
relationship: surrounds UBERON:0000164 ! primitive urogenital sinus
property_value: UBPROP:0000011 "Androgen receptor (AR) activation releases instructive signals from UGM that acts on UGS epithelium (UGE) to stimulate cell proliferation, form prostate ductal progenitors (prostatic buds), and regulate cell adhesion dynamics to permit prostatic bud outgrowth" xsd:string

[Term]
id: UBERON:0009846
name: embryonic cloacal epithelium
namespace: uberon
def: "An epithelium that is part of a embryonic cloaca." [OBOL:automatic]
synonym: "cloacal epithelium" BROAD [EHDAA2:0004585]
xref: EHDAA2:0004585
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0009521 ! anal membrane endodermal component
is_a: UBERON:0012481 ! cloacal epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000163 ! embryonic cloaca
relationship: develops_from UBERON:0003353 {source="EHDAA2"} ! epithelium of hindgut
relationship: part_of UBERON:0000163 ! embryonic cloaca
relationship: part_of UBERON:0003929 {source="EHDAA2"} ! digestive tract epithelium

[Term]
id: UBERON:0009850
name: nematode larva
namespace: uberon
def: "A multicellular organism that existence_starts_and_ends_during a nematode larval stage." [OBOL:automatic]
is_a: UBERON:0002548 ! larva
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: existence_starts_and_ends_during UBERON:0004729 ! nematode larval stage
relationship: existence_starts_and_ends_during UBERON:0004729 ! nematode larval stage
property_value: RO:0002175 NCBITaxon:6239

[Term]
id: UBERON:0009854
name: digestive tract diverticulum
namespace: uberon
def: "Branch or outpocketing of the digestive tract." [https://orcid.org/0000-0002-6601-2165]
synonym: "diverticulum of gut" RELATED [FBbt:00100316]
synonym: "intestinal pouch" RELATED []
xref: FBbt:00100316 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0004921 ! subdivision of digestive tract
is_a: UBERON:0009856 ! sac
intersection_of: UBERON:0009856 ! sac
intersection_of: part_of UBERON:0001555 ! digestive tract

[Term]
id: UBERON:0009856
name: sac
namespace: uberon
synonym: "diverticulum" RELATED []
synonym: "pouch" EXACT []
xref: galen:Diverticulum
is_a: UBERON:0000061 ! anatomical structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: has_quality PATO:0001987 ! saccular
relationship: has_quality PATO:0001987 ! saccular

[Term]
id: UBERON:0009870
name: zone of stomach
namespace: uberon
alt_id: UBERON:0009034
def: "A division of the stomach. The stomach can be divided based on mucosal histology (glandular epithelium and gastric glands) and the relative position and type of gastric gland." [ISBN:0073040584, Wikipedia:Stomach#Sections]
synonym: "gastric zone" EXACT [FMA:14558]
synonym: "region of stomach" EXACT []
synonym: "section of stomach" EXACT []
xref: EMAPA:35821
xref: FMA:14558
xref: MA:0002561
xref: SCTID:245415005
xref: Wikipedia:Stomach#Sections
is_a: UBERON:0004921 ! subdivision of digestive tract
is_a: UBERON:0034944 ! zone of organ
intersection_of: UBERON:0034944 ! zone of organ
intersection_of: part_of UBERON:0000945 ! stomach
relationship: part_of UBERON:0000945 ! stomach
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/29/Regions_of_stomach.svg" xsd:anyURI
property_value: editor_note "We follow Kardong in defining stomach regions by gland, but we also include 'body of stomach'. In future we may want to have different partitions of the stomach" xsd:string

[Term]
id: UBERON:0009871
name: nephrogenic zone
namespace: uberon
def: "Outer portion of the renal cortex. Site of formation of medullary and cortical elements." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "cortical nephrogenic niche" EXACT [PMID:29449449]
synonym: "cortical nephrogenic zone" EXACT [PMID:29449449]
synonym: "nephrogenic tissue" RELATED []
xref: EMAPA:27721
xref: http://www.gudmap.org/Images/Organ_Summaries/Metanephros/NZ.png
xref: MA:0002996
is_a: UBERON:0005423 ! developing anatomical structure
relationship: part_of UBERON:0001225 ! cortex of kidney
property_value: UBPROP:0000008 "see http://www.ncbi.nlm.nih.gov/pubmed/12761251 for description of nephrogenic zone in dogfish." xsd:string

[Term]
id: UBERON:0009881
name: anterior lateral plate mesoderm
namespace: uberon
subset: efo_slim
synonym: "ALPM" EXACT [ZFA:0005041]
xref: EFO:0003704
xref: TAO:0005041
xref: ZFA:0005041
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
relationship: part_of UBERON:0003081 {source="ZFA"} ! lateral plate mesoderm

[Term]
id: UBERON:0009883
name: medullary ray
namespace: uberon
def: "A renal, cortical lobule, consisting of the ascending or descending limbs of the loop of Henle or of the collecting tubules; medullary rays are regions where parallel arrays of straight tubules travel perpendicular to the capsule and extend from the cortex to the medulla." [MP:0011347, Wikipedia:Bone_marrow_of_ovaryry_ray_(anatomy)]
subset: human_reference_atlas
subset: pheno_slim
synonym: "Ferrein's pyramid" EXACT [MP:0011347]
synonym: "kidney medullary ray" EXACT [MP:0011347]
synonym: "renal medullary ray" EXACT [MP:0011347]
xref: BTO:0001155
xref: EMAPA:37906 {source="MA:th"}
xref: FMA:74299
xref: Wikipedia:Bone_marrow_of_ovaryry_ray_(anatomy)
is_a: UBERON:0000064 {source="FMA"} ! organ part
relationship: contributes_to_morphology_of UBERON:0001225 ! cortex of kidney
relationship: overlaps UBERON:0001231 ! nephron tubule
relationship: part_of UBERON:0001225 {source="MP"} ! cortex of kidney
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "FMA says parenchyma, MP says cortex" xsd:string {external_ontology="FMA"}
property_value: UBPROP:0000013 "Their name is potentially misleading -- the 'medullary' refers to their destination, not their location. They are located only in the renal cortex, and not in the renal medulla" xsd:string

[Term]
id: UBERON:0009885
name: interlobar artery
namespace: uberon
def: "An artery that supplies a renal lobe." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Interlobar_arteries]
subset: human_reference_atlas
subset: pheno_slim
synonym: "arteriae interlobares renis" EXACT OMO:0003004 [FMA:TA]
synonym: "arteriae interlobares renis" RELATED OMO:0003011 [Wikipedia:Interlobar_arteries]
synonym: "interlobar arteries of kidney" RELATED [FMA:71637]
synonym: "interlobar artery of kidney" EXACT [FMA:71637]
synonym: "kidney interlobar artery" EXACT []
synonym: "renal interlobar artery" EXACT [MP:0011355]
synonym: "set of interlobar arteries of kidney" RELATED [FMA:71637]
xref: EMAPA:37091 {source="MA:th"}
xref: FMA:71637
xref: SCTID:62802007
xref: Wikipedia:Interlobar_arteries
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0009913 ! renal lobe
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0009913 ! renal lobe
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "FMA only has the set term" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0009887
name: interlobar vein
namespace: uberon
def: "The interlobar veins are veins of the renal circulation which drain the renal lobes." [Wikipedia:Interlobar_veins]
subset: human_reference_atlas
synonym: "interlobar vein of kidney" EXACT [FMA:71631]
synonym: "interlobar veins of kidney" RELATED [FMA:71631]
synonym: "set of interlobar veins of kidney" RELATED [FMA:71631]
synonym: "venae interlobares renis" EXACT OMO:0003004 [FMA:TA]
synonym: "venae interlobares renis" RELATED OMO:0003011 [Wikipedia:Interlobar_veins]
xref: FMA:71631
xref: Wikipedia:Interlobar_veins
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0009913 ! renal lobe
relationship: connected_to UBERON:0001140 ! renal vein
relationship: drains UBERON:0009913 ! renal lobe
relationship: part_of RO:0002577 ! system
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "FMA only has the set term" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0009889
name: secondary heart field
namespace: uberon
def: "A specific region of the lateral mesoderm that will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract)." [GO:0003139, GOC:mtg_heart, GOC:rl]
synonym: "anterior heart field" EXACT [PMID:17276708]
synonym: "anterior/second heart field" EXACT [Geisha:syn, NCBITaxon:8782]
synonym: "second heart field" EXACT [XAO:0004186]
synonym: "SHF" RELATED [XAO:0004186]
xref: XAO:0004186
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007688 ! anlage
relationship: anterior_to UBERON:0004140 {source="PMID:17276708"} ! primary heart field
relationship: dorsal_to UBERON:0004140 {source="PMID:17276708"} ! primary heart field
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0003081 {source="GO:0003129"} ! lateral plate mesoderm
property_value: UBPROP:0000001 "extra-cardiac population of mesodermal progenitors that gives rise to the right ventricle and outflow tract[PMID:17276708]." xsd:string {source="PMID:17276708"}
property_value: UBPROP:0000008 "In general, the two studies in chick concluded that the contribution of the SHF was to the outflow tract, whereas the mouse work suggested that the second lineage contributed more broadly to the heart, including the outflow tract and much or all of the right ventricle [11-14]. These different conclusions may represent differences in the experimental approaches used or may represent bona fide differences in the contribution of the second lineage to the hearts of birds compared to mammals [11]. Alternatively, the secondary/anterior heart fields described in the chick may represent a subset of a broader field that makes a more substantial contribution to the heart, as the mouse studies suggested" xsd:string {source="PMID:17276708"}
property_value: UBPROP:0000011 "in mouse has left ventricular identity[PMID:22855565]" xsd:string

[Term]
id: UBERON:0009891
name: facial mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a developing face." [OBOL:automatic]
synonym: "face mesenchyme" EXACT []
synonym: "mesenchyme of face" EXACT []
xref: EMAPA:35337
xref: FMA:302884
is_a: UBERON:0005253 ! head mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0001456 ! face
relationship: part_of UBERON:0001456 ! face

[Term]
id: UBERON:0009911
name: lobule
namespace: uberon
subset: upper_level
synonym: "lobulus" EXACT OMO:0003011 [FMA:45737, FMA:TA]
xref: FMA:45737
xref: NCIT:C12990
xref: UMLS:C0921005 {source="ncithesaurus:Lobule"}
is_a: UBERON:0000063 {source="cjm"} ! organ subunit
property_value: editor_note "todo - provide definition. Clearly distinguish between lobules, lobes and acinar parts of glands (see for example lobule of mammary gland)" xsd:string

[Term]
id: UBERON:0009912
name: anatomical lobe
namespace: uberon
def: "A portion of an organ, such as the liver, lung, breast, or brain." [ncithesaurus:Lobe]
subset: upper_level
synonym: "lobus" EXACT OMO:0003011 [FMA:45728, FMA:TA]
xref: FMA:45728
xref: NCIT:C13393
xref: UMLS:C0796494
is_a: UBERON:0000063 {source="cjm"} ! organ subunit

[Term]
id: UBERON:0009913
name: renal lobe
namespace: uberon
def: "The portion of a kidney consisting of a renal medullary pyramid and the renal cortex above it[MP]. It is composed of many renal lobules[WP]." [MP:0011381, Wikipedia:Renal_lobe]
subset: pheno_slim
synonym: "kidney lobe" EXACT [MP:0011381]
synonym: "lobi renales" RELATED OMO:0003011 [Wikipedia:Renal_lobe]
synonym: "lobi renalis" EXACT OMO:0003004 [Wikipedia:Renal_lobe]
synonym: "lobus renalis" EXACT [http://www.mondofacto.com/facts/dictionary?lobus+renalis]
xref: FMA:17881
xref: NCIT:C32894
xref: UMLS:C0736382 {source="ncithesaurus:Kidney_Lower_Lobe"}
xref: Wikipedia:Renal_lobe
is_a: UBERON:0009912 ! anatomical lobe
intersection_of: UBERON:0009912 ! anatomical lobe
intersection_of: part_of UBERON:0002113 ! kidney
relationship: contributes_to_morphology_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0002113 ! kidney
property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png" xsd:anyURI
property_value: editor_note "todo - add has_part relationships." xsd:string
property_value: UBPROP:0000008 "human kidneys have multilobar (multipyramidal) architecture while mice and rats have unilobar (unipyramidal) kidneys" xsd:string {source="MP"}

[Term]
id: UBERON:0009914
name: renal lobule
namespace: uberon
def: "The portion of a renal lobe consisting of nephrons grouped around a single medullary ray and draining into a single collecting duct; human kidneys have multilobular, multipapillary architecture while mice and rats have unilobular, unipapillary kidneys." [MP:0011382, Wikipedia:Cortical_lobule]
comment: Alternate definition: One of the subdivisions of the kidney, consisting of a medullary ray and that portion of the convoluted port (renal corpuscles and convoluted tubules) associated with its collecting duct. -http://www.mondofacto.com/facts/dictionary?lobulus+corticalis+renalis
subset: pheno_slim
synonym: "cortical lobule" RELATED [MP:0011382, Wikipedia:Cortical_lobule]
synonym: "cortical lobule of kidney" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis]
synonym: "kidney lobule" EXACT [MP:0011382]
synonym: "lobuli corticales renis" RELATED OMO:0003011 [Wikipedia:Cortical_lobule]
synonym: "lobulus corticalis renalis" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis]
synonym: "lobulus renalis" EXACT []
synonym: "renal cortical lobule" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis]
synonym: "renculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis]
synonym: "reniculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis]
synonym: "renunculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis]
xref: FMA:17670
xref: SCTID:361330004
xref: Wikipedia:Cortical_lobule
is_a: UBERON:0009911 ! lobule
intersection_of: UBERON:0009911 ! lobule
intersection_of: part_of UBERON:0002113 ! kidney
relationship: contributes_to_morphology_of UBERON:0002113 ! kidney
relationship: has_part UBERON:0001285 ! nephron
relationship: has_part UBERON:0009883 ! medullary ray
relationship: part_of UBERON:0009913 {source="FMA"} ! renal lobe

[Term]
id: UBERON:0009916
name: wall of ureter
namespace: uberon
def: "An anatomical wall that is part of a ureter." [OBOL:automatic]
synonym: "ureteral wall" EXACT [FMA:15888]
xref: FMA:15888
xref: SCTID:279397004
is_a: UBERON:0000060 ! anatomical wall
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000056 ! ureter
relationship: has_part UBERON:0005742 ! adventitia
relationship: has_part UBERON:0006660 ! muscular coat
relationship: part_of UBERON:0000056 ! ureter

[Term]
id: UBERON:0009919
name: ureter smooth muscle
namespace: uberon
def: "The smooth muscle tissue surrounding the epithelium of the ureter." [MP:0011426]
subset: human_reference_atlas
subset: pheno_slim
synonym: "ureteral smooth muscle" EXACT [MP:0011426]
synonym: "ureteral smooth muscle layer" EXACT [EMAPA:28844]
xref: EMAPA:28811
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0000056 ! ureter
relationship: contributes_to_morphology_of UBERON:0000056 ! ureter
relationship: part_of UBERON:0006855 ! muscular coat of ureter
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0009920
name: optic neural crest
namespace: uberon
xref: EHDAA2:0001315
xref: EHDAA:1122
is_a: UBERON:0007213 ! mesenchyme derived from head neural crest
is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population
relationship: part_of UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest

[Term]
id: UBERON:0009953
name: post-embryonic organism
namespace: uberon
def: "A multicellular organism that existence_starts_with a post-embryonic stage." [OBOL:automatic]
synonym: "post-hatching organism" NARROW [https://orcid.org/0000-0002-6601-2165]
synonym: "post-natal organism" NARROW [https://orcid.org/0000-0002-6601-2165]
synonym: "postnatal mouse" NARROW [MA:0002405]
synonym: "postnatal organism" EXACT []
synonym: "TS28 mouse" NARROW [MA:0002405]
xref: MA:0002405
is_a: UBERON:0000468 ! multicellular organism
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: existence_starts_with UBERON:0000092 ! post-embryonic stage
relationship: existence_starts_with UBERON:0000092 ! post-embryonic stage
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/667" xsd:anyURI

[Term]
id: UBERON:0009955
name: neurogenic placode
namespace: uberon
def: "Cranial ectodermal placode with potential to develop into a component of the nervous system, such as nerves or ganglia." [http://orcid.org/0000-0002-6601-2165, PMID:11523831]
subset: efo_slim
synonym: "neurogenic placodes" EXACT OMO:0003004 [ZFA:0001309]
synonym: "placodae neurogenicae" RELATED OMO:0003011 [Wikipedia:Neurogenic_placodes]
xref: EFO:0003460
xref: TAO:0001309
xref: Wikipedia:Neurogenic_placodes
xref: XAO:0004620
xref: ZFA:0001309
is_a: UBERON:0002546 {source="cjm"} ! cranial placode
intersection_of: UBERON:0005085 ! ectodermal placode
intersection_of: has_potential_to_developmentally_contribute_to CL:0000540 ! neuron
intersection_of: has_potential_to_developmentally_contribute_to UBERON:0001714 ! cranial ganglion
intersection_of: has_potential_to_developmentally_contribute_to UBERON:0001785 ! cranial nerve
disjoint_from: UBERON:0011814 ! non-neurogenic ectodermal placode
relationship: develops_from UBERON:2007013 ! preplacodal ectoderm
relationship: has_potential_to_developmentally_contribute_to CL:0000540 ! neuron
relationship: has_potential_to_developmentally_contribute_to UBERON:0001714 ! cranial ganglion
relationship: has_potential_to_developmentally_contribute_to UBERON:0001785 ! cranial nerve
property_value: curator_notes "Includes: trigeminal, otic, lateral line and epibranchial placodes." xsd:string
property_value: UBPROP:0000008 "While some sensory placodes (otic and olfactory) may have homologues in basal chordates (Wada et al., 1998), the so-called neurogenenic placodes (trigeminal, otic, lateral line and epibranchial placodes) appear to have emerged at a later time (Shimeld and Holland, 2000)" xsd:string {source="NCBIBook:NBK53171"}

[Term]
id: UBERON:0009958
name: bladder lumen
namespace: uberon
def: "An anatomical space that is enclosed by a urinary bladder." [OBOL:automatic]
synonym: "bladder cavity" EXACT [FMA:15924]
synonym: "cavity of urinary bladder" EXACT [FMA:15924]
synonym: "lumen of urinary bladder" EXACT [FMA:15924]
synonym: "urinary bladder lumen" EXACT [FMA:15924]
xref: EHDAA2:0004058
xref: FMA:15924
xref: galen:UrinaryBladderCavity
xref: SCTID:279405003
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 {source="FMA"} ! anatomical space
intersection_of: luminal_space_of UBERON:0001255 {source="FMA"} ! urinary bladder
relationship: develops_from UBERON:0009844 {source="EHDAA2"} ! urogenital sinus lumen
relationship: luminal_space_of UBERON:0001255 ! urinary bladder
relationship: part_of UBERON:0001255 {source="FMA"} ! urinary bladder

[Term]
id: UBERON:0009970
name: epithelium of pancreatic duct
namespace: uberon
def: "An epithelium that is part of a pancreatic duct." [OBOL:automatic]
subset: efo_slim
synonym: "pancreatic duct epithelium" EXACT [FMA:67681]
synonym: "pancreatic ductal epithelium" EXACT [FMA:67681]
xref: EFO:0002556
xref: FMA:67681
is_a: UBERON:0010371 ! ecto-epithelium
is_a: UBERON:0013697 ! exocrine pancreas epithelium
is_a: UBERON:0034969 ! epithelial layer of duct
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0007329 ! pancreatic duct
relationship: part_of UBERON:0007329 ! pancreatic duct
property_value: editor_note "in EHDAA2, the embryonic pancreatic ducts (dorsal, ventral) are classified as eithelial sacs, which would render them subclasses of this" xsd:string

[Term]
id: UBERON:0009972
name: ureteropelvic junction
namespace: uberon
def: "The junction between the ureter and the renal pelvis of the kidney." [MP:0011487]
subset: pheno_slim
synonym: "pelviureteric junction" EXACT [FMA:15898]
synonym: "pelvoureteric junction" EXACT []
xref: EMAPA:37782 {source="MA:th"}
xref: FMA:15898
xref: MA:0003021
xref: NCIT:C106203
xref: SCTID:264130006
is_a: UBERON:0007651 ! anatomical junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0000056 ! ureter
intersection_of: connects UBERON:0001224 ! renal pelvis
relationship: connects UBERON:0000056 ! ureter
relationship: connects UBERON:0001224 ! renal pelvis
relationship: contributes_to_morphology_of UBERON:0001008 ! renal system
relationship: part_of UBERON:0001008 {source="MP"} ! renal system

[Term]
id: UBERON:0009973
name: ureterovesical junction
namespace: uberon
def: "The valve-like structure found at the site of entry of the ureter into the urinary bladder, normally displays an oblique angulation through the detrusor to avoid reflux of urine up the ureters and the kidney." [MP:0011488]
subset: pheno_slim
synonym: "vesico-ureteral junction" EXACT [MA:0003020]
synonym: "vesico-ureteric junction" EXACT []
synonym: "vesicoureteric junction" EXACT []
xref: EMAPA:37783 {source="MA:th"}
xref: FMA:15899
xref: MA:0003020
xref: NCIT:C106202
xref: SCTID:261187001
is_a: UBERON:0003978 ! valve
is_a: UBERON:0007651 ! anatomical junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0000056 ! ureter
intersection_of: connects UBERON:0001255 ! urinary bladder
relationship: connects UBERON:0000056 ! ureter
relationship: connects UBERON:0001255 ! urinary bladder
relationship: contributes_to_morphology_of UBERON:0001008 ! renal system
relationship: part_of UBERON:0001008 {source="MP"} ! renal system

[Term]
id: UBERON:0010000
name: multicellular anatomical structure
namespace: uberon
def: "An anatomical structure that has more than one cell as a part." [CARO:0010000]
subset: common_anatomy
subset: upper_level
synonym: "multicellular structure" EXACT [FBbt:00100313]
xref: CARO:0010000
xref: FBbt:00100313 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0000061 ! anatomical structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: has_quality PATO:0001993 ! multicellular
relationship: has_part CL:0000000 ! cell
relationship: has_quality PATO:0001993 ! multicellular
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0010009
name: aggregate regional part of brain
namespace: uberon
def: "A regional part of brain consisting of multiple brain regions that are not related through a simple volummetric part of hierarchy, e.g., basal ganglia[NIF]." [NLXANAT:20090509]
subset: non_informative
synonym: "set of nuclei of neuraxis" RELATED [FMA:256381]
xref: FMA:256381
xref: NLXANAT:20090509
is_a: UBERON:0034923 ! disconnected anatomical group
intersection_of: UBERON:0034923 ! disconnected anatomical group
intersection_of: has_member UBERON:0002616 ! regional part of brain
intersection_of: part_of UBERON:0000955 ! brain
relationship: has_member UBERON:0002616 ! regional part of brain
relationship: part_of UBERON:0000955 ! brain
property_value: editor_note "May be obsoleted." xsd:string

[Term]
id: UBERON:0010031
name: 6th arch mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a pharyngeal arch 6." [OBOL:automatic]
synonym: "6th branchial arch mesenchyme" RELATED []
synonym: "6th pharyngeal arch mesenchyme" EXACT []
synonym: "pharyngeal arch 6 mesenchyme" RELATED []
xref: EHDAA2:0004076
xref: EMAPA:32765
xref: FMA:318209
is_a: UBERON:0009494 ! pharyngeal arch mesenchymal region
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0003117 ! pharyngeal arch 6
relationship: part_of UBERON:0003117 ! pharyngeal arch 6

[Term]
id: UBERON:0010039
name: food storage organ
namespace: uberon
def: "An organ of the digestive tract that is capable of retaining and storing food." [https://orcid.org/0000-0002-6601-2165]
subset: functional_classification
subset: grouping_class
xref: BSA:0000123
xref: TADS:0000172
xref: TGMA:0001041
is_a: UBERON:0013765 ! digestive system element
relationship: part_of UBERON:0001555 ! digestive tract
relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system
property_value: curator_notes "This is a very broad functionally defined grouping class that collects disparate structures from insects to vertebrates" xsd:string

[Term]
id: UBERON:0010042
name: 1st arch mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a pharyngeal arch 1." [OBOL:automatic]
synonym: "mesenchyme of 1st arch" EXACT [EMAPA:16128]
xref: EMAPA:16128
is_a: UBERON:0009494 ! pharyngeal arch mesenchymal region
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0004362 ! pharyngeal arch 1
relationship: part_of UBERON:0004362 ! pharyngeal arch 1

[Term]
id: UBERON:0010045
name: 1st arch maxillary mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a 1st arch maxillary component." [OBOL:automatic]
synonym: "maxillary component mesenchyme" RELATED []
synonym: "maxillary mesenchyme" RELATED []
synonym: "mesenchyme of maxillary component" EXACT [EMAPA:16391]
xref: EHDAA2:0000041
xref: EMAPA:16391
is_a: UBERON:0010042 ! 1st arch mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0007238 ! 1st arch maxillary component
relationship: part_of UBERON:0007238 ! 1st arch maxillary component

[Term]
id: UBERON:0010046
name: entire pharyngeal arch associated mesenchyme
namespace: uberon
def: "The sum total of mesenchymal tissue in the pharyngeal arch region. Pharyngeal mesenchyme is undifferentiated, loose connective tissue derived mostly from mesoderm, and also contains ectodermally derived neural crest cells." [https://orcid.org/0000-0002-6601-2165, XAO:0004524]
synonym: "associated mesenchyme of pharyngeal region" EXACT [EMAPA:16550]
synonym: "entire branchial arch associated mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "pharyngeal arch associated mesenchyme" EXACT [EHDAA2:0001459]
xref: EHDAA2:0001459
xref: EMAPA:16550
xref: XAO:0004524
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue
relationship: has_developmental_contribution_from UBERON:0003099 {source="cjm"} ! cranial neural crest
relationship: part_of UBERON:0008814 {source="EHDAA2"} ! pharyngeal arch system

[Term]
id: UBERON:0010047
name: oral gland
namespace: uberon
alt_id: UBERON:0003293
def: "Gland of the epithelium lining the oral cavity. The most common are the salivary glands." [ISBN:0073040584]
synonym: "buccal gland" NARROW []
synonym: "gland of oral opening" RELATED []
synonym: "gland of oral region" RELATED []
synonym: "mouth gland" RELATED []
synonym: "oral cavity gland" RELATED []
synonym: "oral region gland" RELATED []
xref: EHDAA2:0001327
xref: EHDAA:2181
xref: EMAPA:16572
xref: EMAPA:16723
xref: VHOG:0000652
is_a: UBERON:0002365 ! exocrine gland
is_a: UBERON:0003408 ! gland of digestive tract
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0000165 ! mouth
relationship: part_of UBERON:0000165 ! mouth
property_value: UBPROP:0000012 "Note that Kardong classifies lacrimal glands here. EHDAA2 includes pituitary primordium, as this develops from oral mucosa" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0010077
name: cuboidal epithelium
namespace: uberon
def: "An epithelium consisting of cuboidal epithelial cells." [Wikipedia:Cuboidal_epithelium]
xref: NCIT:C32415
xref: UMLS:C0682577 {source="ncithesaurus:Cuboidal_Epithelium"}
xref: Wikipedia:Cuboidal_epithelium
is_a: UBERON:0000483 ! epithelium
property_value: editor_note "TODO - coordinate with CL, add cuboidal cell" xsd:string
property_value: UBPROP:0000012 "in NCIT this is glandular" xsd:string {external_ontology="NCIT"}

[Term]
id: UBERON:0010081
name: future common hepatic duct
namespace: uberon
def: "An extrahepatic bile duct that has the potential to develop into a common hepatic duct." [OBOL:automatic]
xref: EHDAA2:0000595
is_a: UBERON:0003703 ! extrahepatic bile duct
is_a: UBERON:0003914 ! epithelial tube
is_a: UBERON:0005911 ! endo-epithelium
is_a: UBERON:0034932 ! epithelium of biliary system
intersection_of: UBERON:0003703 ! extrahepatic bile duct
intersection_of: has_potential_to_develop_into UBERON:0001175 ! common hepatic duct
relationship: develops_from UBERON:0005604 ! extrahepatic part of hepatic duct
relationship: has_potential_to_develop_into UBERON:0001175 ! common hepatic duct

[Term]
id: UBERON:0010083
name: future dermis
namespace: uberon
def: "Mesenchyme that has the potential to develop into a dermis." [OBOL:automatic]
xref: EHDAA2:0000598
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: has_potential_to_develop_into UBERON:0002067 ! dermis
relationship: develops_from UBERON:0003089 {source="EHDAA2"} ! sclerotome
relationship: develops_from UBERON:0004016 {source="XAO"} ! dermatome
relationship: has_potential_to_develop_into UBERON:0002067 ! dermis
relationship: part_of UBERON:0002199 {source="EHDAA2"} ! integument
property_value: editor_note "check development" xsd:string

[Term]
id: UBERON:0010084
name: future diaphragm
namespace: uberon
def: "A structure that will develop into a diaphragm." [http://orcid.org/0000-0002-6601-2165]
xref: EHDAA2:0000599
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0001103 ! diaphragm
relationship: developmentally_induced_by UBERON:0009133 {source="PMID:23586979"} ! pleuroperitoneal membrane
relationship: develops_from UBERON:0005594 {source="PMID:23586979"} ! head somite
relationship: has_potential_to_develop_into UBERON:0001103 ! diaphragm
relationship: located_in UBERON:0002323 {source="EHDAA2"} ! coelemic cavity lumen

[Term]
id: UBERON:0010092
name: future metencephalon
namespace: uberon
def: "A developing anatomical structure that has the potential to develop into a metencephalon." [OBOL:automatic]
xref: EHDAA2:0000623
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0001895 ! metencephalon
relationship: has_potential_to_develop_into UBERON:0001895 ! metencephalon
relationship: part_of UBERON:0002028 ! hindbrain

[Term]
id: UBERON:0010096
name: future myelencephalon
namespace: uberon
def: "A developing anatomical structure that has the potential to develop into a myelencephalon." [OBOL:automatic]
xref: EHDAA2:0000640
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0005290 ! myelencephalon
relationship: has_potential_to_develop_into UBERON:0005290 ! myelencephalon
relationship: part_of UBERON:0002028 ! hindbrain

[Term]
id: UBERON:0010125
name: future superior salivatory nucleus
namespace: uberon
def: "A gray matter that has the potential to develop into a superior salivatory nucleus." [OBOL:automatic]
xref: EHDAA2:0004644
is_a: UBERON:0002020 ! gray matter
intersection_of: UBERON:0002020 ! gray matter
intersection_of: has_potential_to_develop_into UBERON:0002149 ! superior salivatory nucleus
relationship: has_potential_to_develop_into UBERON:0002149 ! superior salivatory nucleus

[Term]
id: UBERON:0010131
name: conducting tissue of heart
namespace: uberon
def: "Any portion of cardiac muscle tissue that is part of the conducting system of heart or the Purkinje fibers." [http://orcid.org/0000-0002-6601-2165]
synonym: "specialized conducting tissue of heart" EXACT [FMA:83378]
synonym: "specialized muscle tissue of heart" EXACT [FMA:83378]
xref: EHDAA2:0004528
xref: FMA:83378
is_a: UBERON:0001133 ! cardiac muscle tissue

[Term]
id: UBERON:0010136
name: epithelial sheet
namespace: uberon
def: "An epithelial sheet is a flat surface consisting of closely packed epithelial cells." [GO:0002011]
is_a: UBERON:0000483 ! epithelium

[Term]
id: UBERON:0010141
name: primitive sex cord of indifferent gonad
namespace: uberon
def: "A sex cord that is part of a indifferent gonad." [OBOL:automatic]
synonym: "indifferent sex cord" EXACT []
synonym: "primitive sex cords" EXACT [EHDAA2:0004051]
xref: EHDAA2:0004051
is_a: UBERON:0004909 ! epithelium of gonad
is_a: UBERON:0005295 ! sex cord
intersection_of: UBERON:0005295 {source="EHDAA2"} ! sex cord
intersection_of: part_of UBERON:0009117 {source="EHDAA2"} ! indifferent gonad
relationship: develops_from UBERON:0005891 {source="EHDAA2"} ! coelomic epithelium
relationship: part_of UBERON:0009117 ! indifferent gonad
property_value: curator_notes "note that this represents the indifferent structure." xsd:string

[Term]
id: UBERON:0010143
name: seminal vesicle fluid
namespace: uberon
def: "A bodily secretion that is produced by a seminal vesicle." [http://orcid.org/0000-0002-6601-2165]
synonym: "secretion of seminal vesicle" EXACT [FMA:62969]
synonym: "seminal fluid" RELATED INCONSISTENT []
synonym: "seminal vesicle secretion" EXACT [FMA:62969]
synonym: "vesicular fluid" BROAD []
xref: BTO:0002053
xref: FMA:62969
xref: MA:0002526
xref: NCIT:C33529
xref: NCIT:C52552
xref: UMLS:C0036614 {source="ncithesaurus:Seminal_Fluid"}
xref: UMLS:C0227987 {source="ncithesaurus:Seminal_Vesicle_Secretion"}
is_a: UBERON:0006530 {source="FMA"} ! seminal fluid
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: produced_by UBERON:0000998 ! seminal vesicle
relationship: produced_by UBERON:0000998 ! seminal vesicle
property_value: UBPROP:0000008 "constitutes 60-70 % of the ejaculate in humans[MP]" xsd:string
property_value: UBPROP:0000009 "important for semen coagulation, sperm motility, and stability of sperm chromatin and suppression of the immune activity in the female reproductive tract[MP]" xsd:string
property_value: UBPROP:0000012 "in ncit, seminal fluid is a subtype of seminal vesicle secretion" xsd:string {external_ontology="ncit"}

[Term]
id: UBERON:0010152
name: skin mucus
namespace: uberon
def: "A mucous secretion that is produced by glands in the epidermis." [http://orcid.org/0000-0002-6601-2165]
synonym: "epidermal mucus" RELATED [BTO:0005082]
synonym: "skin mucous" RELATED []
is_a: UBERON:0000912 ! mucus
intersection_of: UBERON:0000912 ! mucus
intersection_of: produced_by UBERON:0004790 ! skin mucous gland
relationship: produced_by UBERON:0004790 ! skin mucous gland

[Term]
id: UBERON:0010161
name: lumen of blood vessel
namespace: uberon
def: "An anatomical cavity that surrounded_by a blood vessel." [OBOL:automatic]
synonym: "blood vessel lumen" EXACT []
xref: FMA:312610
xref: SCTID:91747007
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0001981 ! blood vessel
relationship: luminal_space_of UBERON:0001981 ! blood vessel
relationship: part_of UBERON:0001981 ! blood vessel

[Term]
id: UBERON:0010162
name: post-anal tail tip
namespace: uberon
def: "The distal end of the tail." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "end of tail" RELATED [MA:0002848]
synonym: "tail tip" EXACT [MA:0002848]
xref: EMAPA:37760 {source="MA:th"}
xref: MA:0002848
xref: XAO:0004057
is_a: UBERON:0011676 ! subdivision of organism along main body axis
intersection_of: UBERON:0011676 ! subdivision of organism along main body axis
intersection_of: distalmost_part_of UBERON:0007812 ! post-anal tail
relationship: distalmost_part_of UBERON:0007812 ! post-anal tail
relationship: part_of UBERON:0007812 {source="MA"} ! post-anal tail

[Term]
id: UBERON:0010183
name: liver trabecula
namespace: uberon
def: "A trabecula that is part of a liver." [GO:0060344, OBOL:automatic]
synonym: "hepatic trabecula" RELATED []
synonym: "liver trabeculae" EXACT OMO:0003004 []
is_a: UBERON:0000440 ! trabecula
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000440 ! trabecula
intersection_of: part_of UBERON:0002107 ! liver
relationship: part_of UBERON:0002107 ! liver

[Term]
id: UBERON:0010186
name: male urethral gland
namespace: uberon
def: "Any of the numerous small mucous-secreting glands located in the wall of the penile urethra." [MGI:anna, MP:0011794]
subset: pheno_slim
synonym: "gland of Littre" EXACT []
synonym: "gland of male urethra" EXACT []
synonym: "glandulae urethrales urethrae masculinae" RELATED OMO:0003011 [Wikipedia:Urethral_gland]
synonym: "Littre's gland" EXACT [FMA:21443]
synonym: "male urethra gland" EXACT []
synonym: "urethral gland (male)" EXACT [FMA:21443]
xref: EMAPA:29645
xref: FMA:21443
xref: NCIT:C49311
xref: SCTID:303562001
xref: UMLS:C1314737 {source="ncithesaurus:Urethral_Gland"}
xref: Wikipedia:Urethral_gland
is_a: UBERON:0001338 ! urethral gland
intersection_of: UBERON:0001338 ! urethral gland
intersection_of: part_of UBERON:0001333 ! male urethra
relationship: part_of UBERON:0001333 ! male urethra

[Term]
id: UBERON:0010187
name: female urethral gland
namespace: uberon
def: "An urethral gland that is part of a female urethra." [OBOL:automatic]
synonym: "female urethra gland" EXACT []
synonym: "gland of female urethra" EXACT []
synonym: "urethral gland (female)" EXACT [FMA:21444]
xref: EMAPA:29653
xref: FMA:21444
xref: SCTID:279476001
is_a: UBERON:0001338 ! urethral gland
intersection_of: UBERON:0001338 ! urethral gland
intersection_of: part_of UBERON:0001334 ! female urethra
relationship: part_of UBERON:0001334 ! female urethra

[Term]
id: UBERON:0010188
name: protuberance
namespace: uberon
def: "A roughly circular bulge in a surface." [EHDAA2:0003250]
xref: AEO:0000205
xref: EHDAA2:0003250
xref: FMA:82506
is_a: UBERON:0034944 {source="FMA"} ! zone of organ
property_value: editor_note "requires review" xsd:string

[Term]
id: UBERON:0010189
name: right atrium venous valve
namespace: uberon
synonym: "right venous valve" RELATED [EHDAA2:0001762]
xref: EHDAA2:0001762
xref: EMAPA:17010
xref: EMAPA:17328
xref: MA:0001872
is_a: UBERON:0005208 ! right atrium valve
is_a: UBERON:0006675 ! venous valve
intersection_of: UBERON:0006675 ! venous valve
intersection_of: part_of UBERON:0002078 ! right cardiac atrium
property_value: UBPROP:0000012 "part_of in EHDAA2. Only child in MA." xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0010190
name: pair of dorsal aortae
namespace: uberon
def: "The paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation." [ISBN:0-914294-08-3, MP:0004787]
subset: pheno_slim
synonym: "paired dorsal aortae" EXACT [EHDAA2:0000410]
xref: EHDAA2:0000410
xref: EMAPA:18606
xref: MA:0000476
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure
relationship: has_part UBERON:0005805 ! dorsal aorta
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0010191 {source="EHDAA2"} ! aortic system

[Term]
id: UBERON:0010191
name: aortic system
namespace: uberon
xref: EHDAA2:0004512
is_a: UBERON:0011216 ! organ system subdivision
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0004571 {source="Wikipedia"} ! systemic arterial system

[Term]
id: UBERON:0010192
name: genital artery
namespace: uberon
def: "One of the laterally paired arteries that supply the gonads." [ISBN:0073040584, Wikipedia:Gonadal_artery]
synonym: "gonadal artery" EXACT []
xref: Wikipedia:Gonadal_artery
is_a: UBERON:0012254 ! abdominal aorta artery
intersection_of: UBERON:0004573 ! systemic artery
intersection_of: supplies UBERON:0000991 ! gonad
relationship: supplies UBERON:0000991 ! gonad

[Term]
id: UBERON:0010194
name: hepatic portal system
namespace: uberon
def: "A portal system that begins in capillaries in the wall of the digestive tract and and runs as the hepatic portal vein to the liver." [ISBN:0073040584]
synonym: "hepatic-portal system" EXACT [AAO:0010225]
synonym: "portal system of liver" EXACT []
xref: AAO:0010225
is_a: UBERON:0005806 ! portal system
relationship: connects UBERON:0001555 ! digestive tract
relationship: connects UBERON:0002107 ! liver
property_value: UBPROP:0000001 "Part of the circulatory system which includes the ventral abdominal vein, pelvic veins, and portal vein and collects blood from the pelvic region, liver, gall bladder and stomach.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010225", ontology="AAO", source="AAO:BJB"}

[Term]
id: UBERON:0010199
name: bona-fide anatomical boundary
namespace: uberon
def: "An anatomical boundary that corresponds to some physical discontinuity." [CARO:0001004]
comment: One might argue that all boundaries are actually fiat in the sense that there must be some fiat element at a fine enough scale of granularity. This ontology choses to ignore this issue as below the level of granularity relevant to anatomy. (DOS121102)
subset: upper_level
xref: CARO:0001004
is_a: UBERON:0000466 {source="CARO"} ! immaterial anatomical entity

[Term]
id: UBERON:0010204
name: tail vasculature
namespace: uberon
def: "A vasculature that is part of a post-anal tail." [OBOL:automatic]
synonym: "post-vent vasculature" EXACT [ZFA:0005037]
synonym: "tail vasculature" RELATED [ZFA:0005037]
xref: TAO:0005037
xref: XAO:0004151
xref: ZFA:0005037
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0007812 ! post-anal tail
relationship: part_of UBERON:0007812 ! post-anal tail
property_value: UBPROP:0000012 "isa blood vessel in XAO" xsd:string {external_ontology="XAO"}

[Term]
id: UBERON:0010227
name: future cardiac atrium
namespace: uberon
def: "Multi-tissue structure that is part of the heart tube and will become the cardiac atrium." [ZFA:0001718]
synonym: "presumptive atrium heart tube" EXACT [ZFA:0001718]
synonym: "primordial atrium" EXACT [FMA:71005]
synonym: "primordial cardiac atrium" EXACT [FMA:71005]
xref: FMA:71005
xref: TAO:0002228
xref: ZFA:0001718
is_a: UBERON:0006598 ! presumptive structure
relationship: has_potential_to_develop_into UBERON:0002081 ! cardiac atrium
relationship: part_of UBERON:0004141 {source="ZFA"} ! heart tube

[Term]
id: UBERON:0010230
name: eyeball of camera-type eye
namespace: uberon
def: "The core globe-shaped component of the camera-type eye." [UBERON:cjm]
subset: pheno_slim
synonym: "bulbus oculi" EXACT []
synonym: "eye" RELATED INCONSISTENT []
synonym: "eye globe" EXACT [VHOG:0001616]
synonym: "eyeball" EXACT [FMA:12513]
synonym: "globe" RELATED [HP:0100886, MIAA:0000283]
xref: FMA:12513
xref: MIAA:0000283
xref: SCTID:244486005
xref: VHOG:0001616
xref: Wikipedia:Globe_(human_eye)
is_a: UBERON:0000020 ! sense organ
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye
relationship: part_of UBERON:0000019 {source="FMA"} ! camera-type eye
property_value: curator_notes "See notes for camera-type eye" xsd:string
property_value: UBPROP:0000202 FMA:264089

[Term]
id: UBERON:0010243
name: merocrine gland
namespace: uberon
def: "An exocrine gland whose secretions are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and thence onto a bodily surface or into the lumen; the gland releases its product and no part of the gland is lost or damaged." [MGI:anna, MP:0013544, Wikipedia:Merocrine]
subset: pheno_slim
xref: BTO:0002324
xref: MA:0003041
xref: Wikipedia:Merocrine
is_a: UBERON:0002365 ! exocrine gland
intersection_of: UBERON:0002365 ! exocrine gland
intersection_of: capable_of GO:0006887 ! exocytosis
relationship: capable_of GO:0006887 ! exocytosis
property_value: UBPROP:0000007 "merocrine" xsd:string

[Term]
id: UBERON:0010252
name: 1st arch mandibular mesenchyme from neural crest
namespace: uberon
def: "Mesenchyme that develops_from a neural crest and is part of a 1st arch mandibular mesenchyme." [OBOL:automatic]
xref: EHDAA2:0000037
is_a: UBERON:0009584 ! 1st arch mandibular mesenchyme
is_a: UBERON:0010259 {source="inferred"} ! 1st arch mesenchyme from neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0002342 ! neural crest
intersection_of: part_of UBERON:0009584 ! 1st arch mandibular mesenchyme
relationship: develops_from UBERON:0007098 ! mandibular neural crest
relationship: part_of UBERON:0009584 {source="EHDAA2"} ! 1st arch mandibular mesenchyme
relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest

[Term]
id: UBERON:0010253
name: 1st arch maxillary mesenchyme from neural crest
namespace: uberon
def: "Mesenchyme that develops_from a neural crest and is part of a 1st arch maxillary mesenchyme." [OBOL:automatic]
xref: EHDAA2:0000044
is_a: UBERON:0010045 ! 1st arch maxillary mesenchyme
is_a: UBERON:0010259 ! 1st arch mesenchyme from neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0002342 ! neural crest
intersection_of: part_of UBERON:0010045 ! 1st arch maxillary mesenchyme
relationship: part_of UBERON:0010045 {source="EHDAA2"} ! 1st arch maxillary mesenchyme
relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest

[Term]
id: UBERON:0010256
name: 4th arch mesenchyme from neural crest
namespace: uberon
def: "Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme." [OBOL:automatic]
synonym: "4th pharyngeal arch mesenchyme derived from neural crest" EXACT [VHOG:0000580]
synonym: "branchial arch 4 mesenchyme from neural crest" RELATED []
synonym: "mesenchyme derived from neural crest of mesenchyme of 4th arch" EXACT [EMAPA:16772]
synonym: "neural crest derived arch 4 mesenchyme" EXACT []
synonym: "pharyngeal arch 4 mesenchyme from neural crest" EXACT []
xref: EHDAA2:0000098
xref: EMAPA:16772
xref: VHOG:0000580
is_a: UBERON:0005691 ! 4th arch mesenchyme
is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest
is_a: UBERON:0010359 ! pharyngeal arch mesenchyme from neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0002342 ! neural crest
intersection_of: part_of UBERON:0005691 ! 4th arch mesenchyme
relationship: part_of UBERON:0005691 {source="EHDAA2"} ! 4th arch mesenchyme
relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest
property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000580", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0010257
name: 6th arch mesenchyme from neural crest
namespace: uberon
def: "Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme." [OBOL:automatic]
synonym: "branchial arch 6 mesenchyme from neural crest" RELATED []
synonym: "neural crest derived arch 6 mesenchyme" EXACT []
synonym: "pharyngeal arch 6 mesenchyme from neural crest" EXACT []
xref: EHDAA2:0004077
is_a: UBERON:0010031 ! 6th arch mesenchyme
is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest
is_a: UBERON:0010359 ! pharyngeal arch mesenchyme from neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0002342 ! neural crest
intersection_of: part_of UBERON:0010031 ! 6th arch mesenchyme
relationship: part_of UBERON:0010031 {source="EHDAA2"} ! 6th arch mesenchyme
relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest

[Term]
id: UBERON:0010258
name: mesenchyme from rhombencephalic neural crest
namespace: uberon
def: "Mesenchyme that develops_from a rhombencephalon neural crest." [OBOL:automatic]
xref: EHDAA2:0004423
is_a: UBERON:0007213 ! mesenchyme derived from head neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0003852 ! rhombencephalon neural crest
relationship: develops_from UBERON:0003852 ! rhombencephalon neural crest
relationship: part_of UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest

[Term]
id: UBERON:0010259
name: 1st arch mesenchyme from neural crest
namespace: uberon
def: "Mesenchyme that develops_from a neural crest and is part of a 1st arch mesenchyme." [OBOL:automatic]
synonym: "branchial arch 1 mesenchyme from neural crest" RELATED []
synonym: "mesenchyme derived from neural crest of mesenchyme of 1st arch" EXACT [EMAPA:16129]
synonym: "neural crest derived arch 1 mesenchyme" EXACT []
synonym: "pharyngeal arch 1 mesenchyme from neural crest" EXACT []
xref: EMAPA:16129
is_a: UBERON:0010042 ! 1st arch mesenchyme
is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest
is_a: UBERON:0010359 ! pharyngeal arch mesenchyme from neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0002342 ! neural crest
intersection_of: part_of UBERON:0010042 ! 1st arch mesenchyme
relationship: part_of UBERON:0010042 ! 1st arch mesenchyme

[Term]
id: UBERON:0010260
name: umbilical blood vessel
namespace: uberon
def: "One of the three blood vessels, usually one large umbilical vein and two small umbilical arteries, buried within Wharton's jelly, that transport blood to and from the placenta, where exchange between the mother and fetus takes place; the umbilical vein carries oxygenated, nutrient-rich blood from the placenta to the fetus, and the umbilical arteries carry deoxygenated, nutrient-depleted blood from the fetus to the placenta." [MP:0003230]
subset: pheno_slim
synonym: "allantoic vessel" EXACT [Hymans:Hymans]
synonym: "umbilical cord blood vessel" EXACT []
synonym: "umbilical cord blood vessels" RELATED OMO:0003004 []
synonym: "umbilical vasculature" RELATED []
synonym: "umbilical vessel" EXACT []
xref: EMAPA:36493
xref: SCTID:408728001
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: overlaps UBERON:0002331 ! umbilical cord
relationship: located_in UBERON:0003422 ! mesenchyme of umbilical cord
relationship: overlaps UBERON:0002331 ! umbilical cord

[Term]
id: UBERON:0010276
name: space in vertebral column
namespace: uberon
def: "Any anatomical space that is part of a vertebral column." [OBOL:automatic]
synonym: "vertebral column opening" EXACT [AAO:0000700]
synonym: "vertebral conduit" EXACT []
xref: AAO:0000700
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: part_of UBERON:0001130 ! vertebral column
relationship: part_of UBERON:0001130 ! vertebral column

[Term]
id: UBERON:0010285
name: midbrain basal plate
namespace: uberon
def: "Portion of tissue that is dorsolateral to the floor plate and part of the midbrain." [ZFA:0000761]
subset: efo_slim
synonym: "basal plate midbrain" EXACT [TAO:0000761]
synonym: "basal plate midbrain region" EXACT [ZFA:0000761]
xref: DHBA:12322
xref: EFO:0003567
xref: EHDAA2:0004375
xref: TAO:0000761
xref: ZFA:0000761
is_a: UBERON:0002020 {source="EHDAA2"} ! gray matter
relationship: part_of UBERON:0009581 {source="EHDAA2"} ! midbrain mantle layer
relationship: part_of UBERON:0010286 {source="ZFA"} ! midbrain neural tube

[Term]
id: UBERON:0010286
name: midbrain neural tube
namespace: uberon
def: "Portion of neural tube that gives rise to the midbrain." [ZFA:0007039]
xref: TAO:0007039
xref: ZFA:0007039
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
relationship: part_of UBERON:0003080 {source="ZFA"} ! anterior neural tube
property_value: editor_note "we follow ZFA in temporally dividing midbrain NT from presumptive midbrain, but in future this may be collapsed" xsd:string

[Term]
id: UBERON:0010291
name: layer of sclera
namespace: uberon
xref: Wikipedia:Sclera#Histology
is_a: UBERON:0004923 ! organ component layer
is_a: UBERON:0010313 ! neural crest-derived structure
relationship: part_of UBERON:0001773 {source="cjm"} ! sclera

[Term]
id: UBERON:0010294
name: scleral endothelium
namespace: uberon
def: "An endothelium that is part of a sclera." [OBOL:automatic]
is_a: UBERON:0001986 ! endothelium
is_a: UBERON:0010291 {source="Wikipedia"} ! layer of sclera
is_a: UBERON:0015808 ! eye epithelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0001773 ! sclera

[Term]
id: UBERON:0010295
name: substantia propria of sclera
namespace: uberon
def: "A stroma that is part of a sclera." [OBOL:automatic]
synonym: "scleral stroma" EXACT [FMA:58365]
synonym: "stroma of sclera" EXACT [FMA:58365]
synonym: "subsantia propria" BROAD []
synonym: "subsantia propria sclerae" EXACT [FMA:58365]
synonym: "substantia propria sclerae" EXACT OMO:0003011 [FMA:58365, FMA:TA]
xref: FMA:58365
xref: NCIT:C33652
xref: SCTID:368851004
xref: UMLS:C1704397 {source="ncithesaurus:Substantia_Propria"}
is_a: UBERON:0003891 ! stroma
is_a: UBERON:0010291 {source="Wikipedia"} ! layer of sclera
intersection_of: UBERON:0003891 ! stroma
intersection_of: part_of UBERON:0001773 ! sclera

[Term]
id: UBERON:0010299
name: scleral mesenchyme
namespace: uberon
def: "Mesenchyme surrounding the developing optic cup which develops into the sclera." [https://orcid.org/0000-0002-6601-2165, PMID:16496288]
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: has_potential_to_develop_into UBERON:0001773 ! sclera
relationship: has_potential_to_develop_into UBERON:0001773 ! sclera
relationship: surrounds UBERON:0003072 ! optic cup
property_value: UBPROP:0000011 "The mesenchyme surrounding the developing optic cup differentiates into the sclera, the dense fibrous coat of the eye.. http://www.ncbi.nlm.nih.gov/pubmed/16496288" xsd:string

[Term]
id: UBERON:0010303
name: extraembryonic epithelium
namespace: uberon
def: "An epithelium that is part of a extraembryonic structure." [OBOL:automatic]
synonym: "extra-embryonic epithelium" EXACT []
is_a: UBERON:0000483 ! epithelium
is_a: UBERON:0005292 ! extraembryonic tissue
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000478 ! extraembryonic structure
relationship: part_of UBERON:0000478 ! extraembryonic structure

[Term]
id: UBERON:0010304
name: non-keratinized stratified squamous epithelium
namespace: uberon
def: "Stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesizes but does not accumulate keratin. Examples: epithelium of vagina, epithelium of wall of esophagus." [FMA:45569, Wikipedia:Stratified_squamous_epithelium#Nonkeratinized]
synonym: "epithelium stratificatum squamosum noncornificatum" EXACT [FMA:45569]
synonym: "nonkeratinizing stratified squamous epithelium" EXACT [FMA:45569]
synonym: "stratified squamous non-keratinized epithelium" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "stratified squamous nonkeratinizing epithelium" EXACT [http://orcid.org/0000-0002-6601-2165]
xref: FMA:45569
xref: Wikipedia:Stratified_squamous_epithelium#Nonkeratinized
is_a: UBERON:0006915 {source="FMA"} ! stratified squamous epithelium

[Term]
id: UBERON:0010312
name: immature eye
namespace: uberon
def: "Developing anatomical structure that develops into the eyeball and associated structures." [ZFA:0001678]
synonym: "future eye" EXACT []
xref: TAO:0002201
xref: ZFA:0001678
is_a: UBERON:0005423 ! developing anatomical structure
intersection_of: UBERON:0005423 ! developing anatomical structure
intersection_of: has_developmental_contribution_from UBERON:0003071 ! eye primordium
relationship: develops_from UBERON:0003071 {evidence="definitional"} ! eye primordium
relationship: has_developmental_contribution_from UBERON:0003071 ! eye primordium
property_value: UBPROP:0000001 "Multi-tissue structure that consists of the structures that develop into the retina and lens.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002201", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0010313
name: neural crest-derived structure
namespace: uberon
def: "An anatomical structure that develops from the neural crest." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: develops_from UBERON:0002342 ! neural crest
relationship: develops_from UBERON:0002342 ! neural crest
property_value: curator_notes "Grouping term for query purposes" xsd:string

[Term]
id: UBERON:0010314
name: structure with developmental contribution from neural crest
namespace: uberon
def: "An anatomical structure that has some part that develops from the neural crest." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
is_a: UBERON:0000061 ! anatomical structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: has_developmental_contribution_from UBERON:0002342 ! neural crest
relationship: has_developmental_contribution_from UBERON:0002342 ! neural crest
property_value: curator_notes "Grouping term for query purposes" xsd:string

[Term]
id: UBERON:0010316
name: germ layer / neural crest
namespace: uberon
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0005291 ! embryonic tissue
relationship: develops_from UBERON:0002532 ! epiblast (generic)

[Term]
id: UBERON:0010321
name: skeletal element of eye region
namespace: uberon
def: "A skeletal element that is part of a orbital region." [OBOL:automatic]
synonym: "eye skeleton" RELATED []
synonym: "ocular skeleton" RELATED []
synonym: "skeletal element of orbital region" RELATED []
is_a: UBERON:0004765 ! skeletal element
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0004765 ! skeletal element
intersection_of: part_of UBERON:0004088 ! orbital region
relationship: part_of UBERON:0004088 ! orbital region
relationship: part_of UBERON:0011156 ! facial skeleton

[Term]
id: UBERON:0010323
name: cranial skeletal system
namespace: uberon
def: "Skeletal subdivision of the head including skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000049]
synonym: "cranial skeleton" NARROW []
synonym: "cranium" RELATED INCONSISTENT [ZFA:0000737]
synonym: "osteocranium" NARROW []
xref: AAO:0000109
xref: AAO:0000971
xref: AAO:0010185
xref: TAO:0000737
xref: VSAO:0000049
xref: XAO:0003075
xref: ZFA:0000737
is_a: UBERON:0000075 ! subdivision of skeletal system
relationship: only_in_taxon NCBITaxon:89593 ! Craniata <chordates>
relationship: part_of UBERON:0011137 ! axial skeletal system
property_value: curator_notes "that the cranial skeleton includes the pharyngeal arch skeleton. It is thus more inclusive that the cranium itself, and extends beyond the head in tetrapods. The AAO class called 'skull' belongs here, as it includes the whole splanchnocranium" xsd:string
property_value: editor_note "we use 'cranial skeletal system', so that we can include the skull, which has joints/sutures as parts (recall, we follow FMA in distinguishing between the skeleton and skeletal system - only the latter includes joints)" xsd:string
property_value: UBPROP:0000001 "Bony structure that encases the central nervous system and the primary sense organs of sight, olfaction, hearing, and equilibrium.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000109", ontology="AAO", source="AAO:LAP"}
property_value: UBPROP:0000001 "Skeletal system which is part of the skull, including the splanchnocranium, chondrocranium, and dermatocranium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000737", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0010329
name: paired limb/fin bud mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a limb/fin bud." [OBOL:automatic]
is_a: UBERON:0010377 ! mesenchyme from somatopleure
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0004357 ! paired limb/fin bud
relationship: develops_from UBERON:0010377 {source="EHDAA2-abduced"} ! mesenchyme from somatopleure
relationship: part_of UBERON:0004357 ! paired limb/fin bud

[Term]
id: UBERON:0010333
name: extraembryonic membrane mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a extraembryonic membrane." [OBOL:automatic]
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005292 ! extraembryonic tissue
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0005631 ! extraembryonic membrane
relationship: develops_from UBERON:0005728 {source="EHDAA2-abduced"} ! extraembryonic mesoderm
relationship: part_of UBERON:0005631 ! extraembryonic membrane

[Term]
id: UBERON:0010334
name: maxillary process mesenchyme from neural crest
namespace: uberon
def: "Mesenchyme that develops_from a neural crest and is part of a maxillary process mesenchyme." [OBOL:automatic]
xref: EHDAA2:0004601
is_a: UBERON:0009526 ! maxillary process mesenchyme
is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0002342 ! neural crest
intersection_of: part_of UBERON:0009526 ! maxillary process mesenchyme
relationship: develops_from UBERON:0010253 {source="EHDAA2"} ! 1st arch maxillary mesenchyme from neural crest
relationship: part_of UBERON:0009526 {source="EHDAA2"} ! maxillary process mesenchyme

[Term]
id: UBERON:0010335
name: maxillary process mesenchyme from head mesenchyme
namespace: uberon
def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a maxillary process mesenchyme." [OBOL:automatic]
xref: EHDAA2:0004602
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0009526 ! maxillary process mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm
intersection_of: part_of UBERON:0009526 ! maxillary process mesenchyme
relationship: develops_from UBERON:0010338 {source="EHDAA2"} ! 1st arch maxillary mesenchyme from head mesenchyme
relationship: part_of UBERON:0009526 {source="EHDAA2"} ! maxillary process mesenchyme

[Term]
id: UBERON:0010336
name: mandibular process mesenchyme from neural crest
namespace: uberon
def: "Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme." [OBOL:automatic]
xref: EHDAA2:0004603
is_a: UBERON:0006905 ! mandibular process mesenchyme
is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0002342 ! neural crest
intersection_of: part_of UBERON:0006905 ! mandibular process mesenchyme
relationship: develops_from UBERON:0010252 {source="EHDAA2"} ! 1st arch mandibular mesenchyme from neural crest
relationship: part_of UBERON:0006905 {source="EHDAA2"} ! mandibular process mesenchyme

[Term]
id: UBERON:0010337
name: mandibular process mesenchyme from head mesenchyme
namespace: uberon
def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme." [OBOL:automatic]
xref: EHDAA2:0004604
is_a: UBERON:0006904 ! head mesenchyme from mesoderm
is_a: UBERON:0006905 ! mandibular process mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm
intersection_of: part_of UBERON:0006905 ! mandibular process mesenchyme
relationship: develops_from UBERON:0010339 {source="EHDAA2"} ! 1st arch mandibular mesenchyme from head mesenchyme
relationship: part_of UBERON:0006905 {source="EHDAA2"} ! mandibular process mesenchyme

[Term]
id: UBERON:0010338
name: 1st arch maxillary mesenchyme from head mesenchyme
namespace: uberon
def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch maxillary mesenchyme." [OBOL:automatic]
xref: EHDAA2:0000043
is_a: UBERON:0010045 ! 1st arch maxillary mesenchyme
is_a: UBERON:0010341 ! 1st arch mesenchyme from head mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm
intersection_of: part_of UBERON:0010045 ! 1st arch maxillary mesenchyme
relationship: part_of UBERON:0010045 {source="EHDAA2"} ! 1st arch maxillary mesenchyme

[Term]
id: UBERON:0010339
name: 1st arch mandibular mesenchyme from head mesenchyme
namespace: uberon
def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme." [OBOL:automatic]
xref: EHDAA2:0000036
is_a: UBERON:0009584 ! 1st arch mandibular mesenchyme
is_a: UBERON:0010341 ! 1st arch mesenchyme from head mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm
intersection_of: part_of UBERON:0009584 ! 1st arch mandibular mesenchyme
relationship: part_of UBERON:0009584 {source="EHDAA2"} ! 1st arch mandibular mesenchyme

[Term]
id: UBERON:0010341
name: 1st arch mesenchyme from head mesenchyme
namespace: uberon
def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme." [OBOL:automatic]
synonym: "mesenchyme derived from head mesoderm of mesenchyme of 1st arch" EXACT [EMAPA:16130]
xref: EMAPA:16130
is_a: UBERON:0006904 ! head mesenchyme from mesoderm
is_a: UBERON:0010042 ! 1st arch mesenchyme
is_a: UBERON:0010360 ! pharyngeal arch mesenchyme from head mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm
intersection_of: part_of UBERON:0010042 ! 1st arch mesenchyme
relationship: part_of UBERON:0010042 {source="EMAPA"} ! 1st arch mesenchyme

[Term]
id: UBERON:0010345
name: 4th arch mesenchyme from head mesenchyme
namespace: uberon
def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme." [OBOL:automatic]
synonym: "branchial arch 4 mesenchyme from head mesenchyme" RELATED []
synonym: "head mesenchyme derived arch 4 mesenchyme" EXACT []
synonym: "mesenchyme derived from head mesoderm of mesenchyme of 4th arch" EXACT [EMAPA:16771]
synonym: "pharyngeal arch 4 mesenchyme from head mesenchyme" EXACT []
xref: EHDAA2:0000097
xref: EMAPA:16771
is_a: UBERON:0005691 ! 4th arch mesenchyme
is_a: UBERON:0006904 ! head mesenchyme from mesoderm
is_a: UBERON:0010360 ! pharyngeal arch mesenchyme from head mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm
intersection_of: part_of UBERON:0005691 ! 4th arch mesenchyme
relationship: part_of UBERON:0005691 {source="EHDAA2"} ! 4th arch mesenchyme

[Term]
id: UBERON:0010347
name: 6th arch mesenchyme from head mesenchyme
namespace: uberon
def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme." [OBOL:automatic]
synonym: "branchial arch 6 mesenchyme from head mesenchyme" RELATED []
synonym: "head mesenchyme derived arch 6 mesenchyme" EXACT []
synonym: "pharyngeal arch 6 mesenchyme from head mesenchyme" EXACT []
xref: EHDAA2:0004078
is_a: UBERON:0006904 ! head mesenchyme from mesoderm
is_a: UBERON:0010031 ! 6th arch mesenchyme
is_a: UBERON:0010360 ! pharyngeal arch mesenchyme from head mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm
intersection_of: part_of UBERON:0010031 ! 6th arch mesenchyme
relationship: part_of UBERON:0010031 {source="EHDAA2"} ! 6th arch mesenchyme

[Term]
id: UBERON:0010359
name: pharyngeal arch mesenchyme from neural crest
namespace: uberon
def: "Mesenchyme that develops_from a neural crest and is part of a entire pharyngeal arch associated mesenchyme." [OBOL:automatic]
comment: Partially implements https://github.com/obophenotype/uberon/wiki/The-neural-crest NC meeting scheme
synonym: "arch mesenchyme from neural crest" EXACT []
synonym: "branchial arch mesenchyme from neural crest" EXACT []
synonym: "neural crest derived arch mesenchyme" EXACT []
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0014387 ! mesenchyme derived from neural crest
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0002342 ! neural crest
intersection_of: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme
relationship: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme

[Term]
id: UBERON:0010360
name: pharyngeal arch mesenchyme from head mesenchyme
namespace: uberon
def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a entire pharyngeal arch associated mesenchyme." [OBOL:automatic]
comment: Partially implements https://github.com/obophenotype/uberon/wiki/The-neural-crest NC meeting scheme
synonym: "arch mesenchyme from head mesenchyme" EXACT []
synonym: "branchial arch mesenchyme from head mesenchyme" EXACT []
synonym: "head mesenchyme derived arch mesenchyme" EXACT []
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm
intersection_of: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme
relationship: develops_from UBERON:0006904 ! head mesenchyme from mesoderm
relationship: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme

[Term]
id: UBERON:0010362
name: endoskeleton
namespace: uberon
def: "Skeletal subdivision that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000037]
synonym: "replacement skeleton" EXACT [VSAO:curator]
xref: VSAO:0000037
xref: Wikipedia:Endoskeleton
xref: XAO:0004026
is_a: UBERON:0010912 {source="VSAO"} ! subdivision of skeleton
relationship: composed_primarily_of UBERON:0010522 ! replacement element
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
property_value: UBPROP:0000001 "An endoskeleton is an internal support structure of an animal, composed of mineralized tissue. Endoskeleton develops within the skin or in the deeper body tissues. The vertebrate is basically an endoskeleton made up of two types of tissues (bone and cartilage). During early embryonic development the endoskeleton is composed of notochord and cartilage. The notochord in most vertebrates is replaced by vertebral column and cartilage is replaced by bone in most adults. In three phyla and one subclass of animals, endoskeletons of various complexity are found: Chordata, Echinodermata, Porifera, and Coleoidea. An endoskeleton may function purely for support (as in the case of sponges), but often serves as an attachment site for muscle and a mechanism for transmitting muscular forces. A true endoskeleton is derived from mesodermal tissue. Such a skeleton is present in echinoderms and chordates. The poriferan 'skeleton' consists of microscopic calcareous or siliceous spicules or a spongin network. The Coleoidae do not have a true endoskeleton in the evolutionary sense; here, a mollusk exoskeleton evolved into several sorts of internal structure, the 'cuttlebone' of cuttlefish being the best-known version. Yet they do have cartilaginous tissue in their body, even if it is not mineralized, especially in the head, where it forms a primitive cranium. The endoskeleton gives shape,support and protection to the body and provides a mean of locomotion.[Wikipedia:Endoskeleton]t" xsd:string {source="Wikipedia:Endoskeleton"}

[Term]
id: UBERON:0010363
name: endochondral element
namespace: uberon
def: "A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000139]
synonym: "endochondral replacement element" EXACT [VSAO:0000139]
xref: VSAO:0000139
xref: XAO:0004017
xref: ZFA:0005620
is_a: UBERON:0004765 {source="VSAO"} ! skeletal element
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0010364
name: dermal skeleton
namespace: uberon
def: "Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000035]
comment: This ontology covers metazoa, so we do not use exoskeleton as primary label, as in VSAO
synonym: "dermal skeletal system" RELATED [VSAO:curator]
synonym: "dermoskeleton" RELATED [VSAO:curator]
synonym: "desmoskeleton" RELATED [VSAO:curator]
synonym: "exoskeleton" BROAD INCONSISTENT [VSAO:curator]
xref: VSAO:0000035
xref: XAO:0004025
is_a: UBERON:0010912 {source="VSAO"} ! subdivision of skeleton
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>

[Term]
id: UBERON:0010368
name: pulmonary lobule
namespace: uberon
def: "The smallest anatomical unit of the lung, measuring 0.50 to 2.00 cm in diameter. Each lobule is composed of 4-8 terminal bronchioles and their distal alveolar ducts and sacs. The lobules are separated by fibrous interlobular septa." [ncithesaurus:Pulmonary_Lobule]
synonym: "lobulus pulmonis" EXACT OMO:0003011 [FMA:75739, FMA:TA]
xref: FMA:75739
xref: NCIT:C33428
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0009911 ! lobule
intersection_of: UBERON:0009911 ! lobule
intersection_of: part_of UBERON:0002048 ! lung
relationship: part_of UBERON:8600017 ! bronchopulmonary segment

[Term]
id: UBERON:0010371
name: ecto-epithelium
namespace: uberon
def: "Epithelium composed of cells that develops from the ectoderm[FMA,modified]." [FMA:69064]
synonym: "ectoderm-derived epithelium" EXACT []
xref: FMA:69064
is_a: UBERON:0000483 ! epithelium
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000483 ! epithelium
intersection_of: develops_from UBERON:0000924 ! ectoderm
relationship: composed_primarily_of CL:0002077 ! ecto-epithelial cell

[Term]
id: UBERON:0010375
name: pancreas dorsal primordium
namespace: uberon
synonym: "dorsal pancreas" RELATED INCONSISTENT [FMA:79793]
xref: EHDAA2:0001384
xref: FMA:79793
is_a: UBERON:0001048 ! primordium
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0001048 ! primordium
intersection_of: has_potential_to_develop_into UBERON:0009708 ! dorsal pancreas
relationship: has_potential_to_develop_into UBERON:0009708 ! dorsal pancreas
relationship: part_of UBERON:0003921 {source="EHDAA2"} ! pancreas primordium
property_value: editor_note "consider merging with dorsal pancreatic bud. Starts at CS12 in human (EHDAA2, embryology.ch 'bud anlagen')" xsd:string

[Term]
id: UBERON:0010376
name: pancreas ventral primordium
namespace: uberon
synonym: "ventral pancreas" RELATED INCONSISTENT [FMA:79794]
xref: EHDAA2:0001387
xref: FMA:79794
is_a: UBERON:0001048 ! primordium
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0001048 ! primordium
intersection_of: has_potential_to_develop_into UBERON:0009709 ! ventral pancreas
relationship: has_potential_to_develop_into UBERON:0009709 ! ventral pancreas
relationship: part_of UBERON:0003921 {source="EHDAA2"} ! pancreas primordium
property_value: UBPROP:0000008 "Starts at CS14 in human (EHDAA2) or CS13-14 (embryology.ch 'bud anlagen')" xsd:string

[Term]
id: UBERON:0010377
name: mesenchyme from somatopleure
namespace: uberon
def: "Mesenchyme that develops_from a somatopleure." [OBOL:automatic]
xref: EHDAA2:0001120
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0004874 ! somatopleure
intersection_of: part_of UBERON:0000922 ! embryo
relationship: develops_from UBERON:0004874 ! somatopleure
relationship: part_of UBERON:0009142 {source="EHDAA2"} ! entire embryonic mesenchyme
property_value: editor_note "the way this class is defined also includes extraembryonic mesenchyme such as the amniotic mesenchyme; in future this may be restricted to embryonic derivatives" xsd:string

[Term]
id: UBERON:0010378
name: mesenchyme from splanchnopleure
namespace: uberon
def: "Mesenchyme that develops_from a splanchnopleure." [OBOL:automatic]
xref: EHDAA2:0001122
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0004873 ! splanchnopleure
intersection_of: part_of UBERON:0000922 ! embryo
relationship: develops_from UBERON:0004873 ! splanchnopleure
relationship: part_of UBERON:0009142 {source="EHDAA2"} ! entire embryonic mesenchyme

[Term]
id: UBERON:0010390
name: lumen of urethra
namespace: uberon
def: "An organ cavity that is part of a urethra." [OBOL:automatic]
synonym: "urethral lumen" EXACT [FMA:19709]
xref: FMA:19709
xref: SCTID:279432008
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000057 ! urethra
relationship: luminal_space_of UBERON:0000057 ! urethra
relationship: part_of UBERON:0000057 ! urethra

[Term]
id: UBERON:0010399
name: spleen trabecular artery
namespace: uberon
def: "One of the branches of the splenic artery[MP]." [MP:0002354, Wikipedia:Trabecular_arteries]
subset: human_reference_atlas
subset: pheno_slim
synonym: "trabecular artery" RELATED []
xref: MA:0000759
xref: NCIT:C49775
xref: UMLS:C1710159 {source="ncithesaurus:Splenic_Trabecular_Artery"}
xref: Wikipedia:Trabecular_arteries
is_a: UBERON:0001637 ! artery
is_a: UBERON:0003497 ! abdomen blood vessel
intersection_of: UBERON:0001637 ! artery
intersection_of: part_of UBERON:0001265 ! trabecula of spleen
relationship: connecting_branch_of UBERON:0001194 {source="MP"} ! splenic artery
relationship: contributes_to_morphology_of UBERON:0002106 ! spleen
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0001265 ! trabecula of spleen
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "When the splenic artery passes into the trabecula of the spleen and branches, they become known as the trabecular arteries. When these arteries then reach the white pulp, and become covered with Periarteriolar lymphoid sheaths, the name changes again to central arteries (or central arterioles). Branches of the central arteries are given to the red pulp, and these are called penicillar arteries).[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Trabecular_arteries"}

[Term]
id: UBERON:0010400
name: spleen trabecular vein
namespace: uberon
def: "One of the veins that feed the splenic vein." [MP:0002228, Wikipedia:Trabecular_veins]
subset: human_reference_atlas
subset: pheno_slim
synonym: "trabecular vein" RELATED [Wikipedia:Trabecular_veins]
xref: MA:0000760
xref: NCIT:C49779
xref: UMLS:C1710160 {source="ncithesaurus:Splenic_Trabecular_Vein"}
xref: Wikipedia:Trabecular_veins
is_a: UBERON:0013126 ! vein of abdomen
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0001265 ! trabecula of spleen
relationship: connected_to UBERON:0003713 ! splenic vein
relationship: contributes_to_morphology_of UBERON:0002106 ! spleen
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0001265 ! trabecula of spleen
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000001 "The trabecular veins are the largest veins inside the spleen. It drains the blood collected in the sinuses of the pulp.[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Trabecular_veins"}

[Term]
id: UBERON:0010409
name: ocular surface region
namespace: uberon
def: "The integrated unit (of the eye) that consists of the conjunctiva, the corneal surface, and the ocular mucosal adnexa including the lid margins and the meibomian gland openings, the lacrimal glands and the lacrimal drainage system, all which are critical to maintain ocular surface integrity and provide protection from external antigens and pathogenic microorganisms." [MP:0013754]
subset: pheno_slim
synonym: "eye surface" EXACT [MA:0002486]
synonym: "eye surface region" EXACT []
synonym: "ocular surface" EXACT []
xref: EMAPA:35336
xref: MA:0002486
is_a: UBERON:0000063 ! organ subunit
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: part_of UBERON:0000019 ! camera-type eye
relationship: superficial_to UBERON:0022288 ! surface of eyeball

[Term]
id: UBERON:0010418
name: urethral opening
namespace: uberon
def: "An orifice that is part of a lower urinary tract." [OBOL:automatic]
subset: pheno_slim
synonym: "urethral orifice" EXACT [OBOL:automatic]
xref: EMAPA:35965
xref: MA:0002867
is_a: UBERON:0000161 ! orifice
intersection_of: UBERON:0000161 ! orifice
intersection_of: part_of UBERON:0001556 ! lower urinary tract
relationship: part_of UBERON:0001556 ! lower urinary tract

[Term]
id: UBERON:0010427
name: ciliary processes
namespace: uberon
def: "The ciliary processes are formed by the inward folding of the various layers of the choroid, i.e. , the choroid proper and the lamina basalis, and are received between corresponding foldings of the suspensory ligament of the lens." [Wikipedia:Ciliary_processes]
synonym: "ciliary process" RELATED [Wikipedia:Ciliary_processes]
synonym: "ciliary processes" EXACT [FMA:76551]
synonym: "ciliary processes set" EXACT [FMA:76551]
synonym: "processus ciliares" EXACT OMO:0003011 [FMA:TA]
synonym: "processus ciliares" RELATED OMO:0003011 [Wikipedia:Ciliary_processes]
synonym: "set of ciliary processes" EXACT [FMA:76551]
xref: FMA:76551
xref: SCTID:280860001
xref: Wikipedia:Ciliary_processes
is_a: UBERON:0000481 ! multi-tissue structure
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: part_of UBERON:0001775 ! ciliary body
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/Gray875.png" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-eye-l.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-eye-r.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-eye-l.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-eye-r.glb" xsd:anyURI

[Term]
id: UBERON:0010428
name: flat bone
namespace: uberon
def: "A bone that is shaped as a broad flat plate and composed of two thin layers of compact tissue enclosing between them a variable quantity of cancellous tissue, which is the location of red bone marrow." [Wikipedia:Flat_bone]
comment: Examples: cranium, the ilium, sternum, rib cage, the sacrum and the scapula; the occipital, parietal, frontal, nasal, lacrimal, vomer, scapula, os coxC&, sternum, and ribs
synonym: "os planum" RELATED OMO:0003011 [Wikipedia:Flat_bone]
xref: FMA:7476
xref: galen:FlatBone
xref: NCIT:C32616
xref: SCTID:332907008
xref: UMLS:C0222649 {source="ncithesaurus:Flat_Bone"}
xref: Wikipedia:Flat_bone
is_a: UBERON:0001474 {source="FMA"} ! bone element
relationship: has_quality PATO:0000407 ! flat
property_value: UBPROP:0000008 "In an adult mammal, most red blood cells are formed in flat bones" xsd:string
property_value: UBPROP:0000009 "Flat bones are those bones which are found where the principal requirement is either extensive protection or the provision of broad surfaces for muscular attachment" xsd:string

[Term]
id: UBERON:0010498
name: pseudostratified columnar epithelium
namespace: uberon
def: "A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels." [http://medical-dictionary.thefreedictionary.com/pseudostratified+epithelium, Wikipedia:Pseudostratified_columnar_epithelium]
xref: FMA:45572
xref: NCIT:C33419
xref: NCIT:C49316
xref: UMLS:C0836138 {source="ncithesaurus:Pseudostratified_Columnar_Epithelium"}
xref: UMLS:C1514590 {source="ncithesaurus:Pseudostratified_Epithelium"}
xref: Wikipedia:Pseudostratified_columnar_epithelium
is_a: UBERON:0000485 {source="FMA"} ! simple columnar epithelium
property_value: UBPROP:0000009 "Pseudostratified epithelia function in secretion or absorption. If a specimen looks stratified but has cilia, then it is a pseudostratified ciliated epithelium, since stratified epithelia do not have cilia." xsd:string
property_value: UBPROP:0000012 "glandular in NCIT; we consider the two NCIT terms synonymous" xsd:string {external_ontology="NCIT"}

[Term]
id: UBERON:0010499
name: pseudostratified ciliated columnar epithelium
namespace: uberon
def: "Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile." [NCIT:NCIT]
synonym: "epithelium pseudostratificatum columnare ciliatum (trachea et bronchi)" EXACT [FMA:13146]
xref: FMA:13146
xref: NCIT:C13181
xref: UMLS:C0506992 {source="ncithesaurus:Pseudostratified_Columnar_Ciliated_Epithelium"}
is_a: UBERON:0007592 ! ciliated columnar epithelium
is_a: UBERON:0010498 ! pseudostratified columnar epithelium
intersection_of: UBERON:0010498 ! pseudostratified columnar epithelium
intersection_of: has_part CL:0000067 ! ciliated epithelial cell

[Term]
id: UBERON:0010521
name: electroreceptor organ
namespace: uberon
def: "An organ that is capable of detecting electrical stimulus." [http://orcid.org/0000-0002-6601-2165]
synonym: "electric sense organ" EXACT []
synonym: "electroreception organ" EXACT []
is_a: UBERON:0000020 ! sense organ
intersection_of: UBERON:0000062 ! organ
intersection_of: capable_of GO:0050964 ! detection of electrical stimulus involved in electroception
relationship: capable_of GO:0050964 ! detection of electrical stimulus involved in electroception

[Term]
id: UBERON:0010522
name: replacement element
namespace: uberon
def: "Skeletal element that forms as a replacement or substitution of another element or tissue." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000135]
xref: VSAO:0000135
xref: XAO:0004016
xref: ZFA:0005624
is_a: UBERON:0004765 {source="VSAO"} ! skeletal element
relationship: part_of UBERON:0010362 {source="cjm"} ! endoskeleton

[Term]
id: UBERON:0010523
name: microcirculatory vessel
namespace: uberon
def: "A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses." [http://orcid.org/0000-0002-6601-2165, MESH:A07.231.432, ZFA:0005251]
synonym: "microcirculatory vessels" RELATED OMO:0003004 [TAO:0005251]
xref: MESH:D055806
xref: TAO:0005251
xref: ZFA:0005251
is_a: UBERON:0000055 ! vessel
relationship: part_of UBERON:0002049 {source="ZFA"} ! vasculature

[Term]
id: UBERON:0010527
name: cavity of bone organ
namespace: uberon
def: "An organ cavity that surrounded_by a bone." [OBOL:automatic]
synonym: "bone organ cavity" EXACT [FMA:24021]
xref: FMA:24021
is_a: UBERON:0002558 ! organ cavity
intersection_of: UBERON:0002558 ! organ cavity
intersection_of: part_of UBERON:0001474 ! bone element
relationship: part_of UBERON:0001474 ! bone element

[Term]
id: UBERON:0010528
name: pneumatic cavity of bone
namespace: uberon
synonym: "air space of bone" EXACT [FMA:24028]
xref: FMA:24028
is_a: UBERON:0010527 {source="FMA"} ! cavity of bone organ
relationship: part_of UBERON:0008193 ! pneumatized bone

[Term]
id: UBERON:0010531
name: metanephros induced blastemal cells
namespace: uberon
synonym: "cap mesenchyme of metanephros of urinary system" RELATED [EMAPA:17645]
synonym: "induced blastemal cells" EXACT [VHOG:0001241]
synonym: "nephrogenic interstitium" RELATED []
synonym: "nephrogenic interstitium of nephrogenic zone" EXACT [EMAPA:17953]
synonym: "peripheral blastema" RELATED [EMAPA:17953]
xref: EHDAA2:0001143
xref: EHDAA:7007
xref: EHDAA:8105
xref: EMAPA:17953
xref: EMAPA:27621
xref: MA:0002998
xref: VHOG:0001241
is_a: UBERON:0005423 ! developing anatomical structure
relationship: developmentally_induced_by UBERON:0000084 ! ureteric bud
relationship: develops_from UBERON:0003220 {source="EHDAA2"} ! metanephric mesenchyme
relationship: has_part CL:0000354 ! blastemal cell
relationship: part_of UBERON:0009871 ! nephrogenic zone
property_value: UBPROP:0000012 "different versions of EMAPA have different labels for the same classes. In vHOG this is part of metanephros cortex but this leads to a cycle in basic." xsd:string {external_ontology="EMAPA"}

[Term]
id: UBERON:0010532
name: primitive nephron
namespace: uberon
def: "An epithelial tube that is fated to become a nephron." [http://orcid.org/0000-0002-6601-2165]
synonym: "developing nephron" BROAD []
synonym: "future nephron" EXACT []
synonym: "presumptive nephron" EXACT []
synonym: "primitive nephron" BROAD []
is_a: UBERON:0003914 {source="EHDAA2-inferred"} ! epithelial tube
is_a: UBERON:0004819 ! kidney epithelium
is_a: UBERON:0006555 ! excretory tube
relationship: develops_from UBERON:0004209 {source="EHDAA2"} ! renal vesicle
relationship: has_potential_to_develop_into UBERON:0001285 ! nephron
relationship: located_in UBERON:0003918 ! kidney mesenchyme
property_value: UBPROP:0000012 "EHDAA2 treats this as already having a tubular structure, but in the ZFA representation this is a cluster of cells" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0010533
name: metanephros cortex
namespace: uberon
def: "The metanephric cortex is the outer region of the metanephros[GO]." [GO:0072214]
xref: VHOG:0000714
is_a: UBERON:0001225 ! cortex of kidney
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0001225 ! cortex of kidney
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: develops_from UBERON:0005113 ! metanephric cortex mesenchyme
relationship: part_of UBERON:0000081 {source="VHOG"} ! metanephros

[Term]
id: UBERON:0010534
name: primitive mesonephric nephron
namespace: uberon
def: "Anatomical cluster which give rise to mature mesonephric nephrons. Zebrafish continously generate new mesonephric nephrons." [GOC:cvs, https://orcid.org/0000-0002-2244-7917, ZFA:0005584]
synonym: "developing mesonephric nephron" EXACT [ZFA:0005584]
synonym: "primitive mesonephric nephron" EXACT []
xref: ZFA:0005584
is_a: UBERON:0000083 ! mesonephric tubule
is_a: UBERON:0010532 ! primitive nephron
intersection_of: UBERON:0010532 ! primitive nephron
intersection_of: part_of UBERON:0000080 ! mesonephros

[Term]
id: UBERON:0010535
name: primitive metanephric nephron
namespace: uberon
def: "A primitive nephron that is part of a metanephros." [OBOL:automatic]
synonym: "developing metanephric nephron" EXACT []
synonym: "primitive metanephric nephron" EXACT []
synonym: "primitive nephron" BROAD [EHDAA2:0001516]
xref: EHDAA2:0001516
is_a: UBERON:0005106 ! metanephric tubule
is_a: UBERON:0010532 ! primitive nephron
intersection_of: UBERON:0010532 ! primitive nephron
intersection_of: part_of UBERON:0000081 ! metanephros
relationship: part_of UBERON:0005113 {source="EHDAA2"} ! metanephric cortex mesenchyme

[Term]
id: UBERON:0010536
name: nephron progenitor
namespace: uberon
is_a: UBERON:0000479 {source="ZFA"} ! tissue
relationship: has_potential_to_develop_into UBERON:0001285 ! nephron
relationship: part_of UBERON:0003918 {source="cjm"} ! kidney mesenchyme

[Term]
id: UBERON:0010537
name: mesonephric nephron progenitor
namespace: uberon
def: "Cluster of cells comprising a portion of tissue which gives rise to new mesonephric nephrons. The cluster contains self-renewing stem cells." [ZFA:0005587]
xref: ZFA:0005587
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0010536 ! nephron progenitor
intersection_of: UBERON:0010536 ! nephron progenitor
intersection_of: part_of UBERON:0000080 ! mesonephros
relationship: part_of UBERON:0000080 ! mesonephros

[Term]
id: UBERON:0010707
name: appendage girdle complex
namespace: uberon
def: "An organism subdivision that includes both an appendage and its associated girdle region. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc)." [https://github.com/obophenotype/uberon/wiki/Appendages-and-the-appendicular-skeleton, https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "appendage complex" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "appendage-girdle complex" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "appendage/girdle complex" EXACT [VSAO:0000214]
synonym: "girdle plus limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "limb" RELATED INCONSISTENT [FMA:7182]
xref: EMAPA:37858 {source="MA:th"}
xref: FMA:7182
xref: VSAO:0000214
is_a: UBERON:0000475 ! organism subdivision
is_a: UBERON:0015212 ! lateral structure
relationship: functionally_related_to GO:0040011 ! locomotion
relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
property_value: editor_note "It is still called a complex when one of the two parts is missing (?) There are fossil fishes with only an outgrowth (no record of a girdle), including thelodonts (which have a suprabranchial fin) as well as some anaspids which have a distinctive 'paired fin' (with differing published assertions on whether it's homologous to a pec fin or pelvic fin or both or neither). There are many fishes and other vertebrates with only a girdle and no outgrowth.[VSAO]" xsd:string
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-9114-8737
property_value: UBPROP:0000001 "Anatomical group that consists of the soft and skeletal tissues of the appendicular region of the body and the appendage proper.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000214", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070"}
property_value: UBPROP:0000005 "It is still called a complex when one of the two parts is missing (?) There are fossil fishes with only an outgrowth (no record of a girdle), including thelodonts (which have a suprabranchial fin) as well as some anaspids which have a distinctive 'paired fin' (with differing published assertions on whether it's homologous to a pec fin or pelvic fin or both or neither). There are many fishes and other vertebrates with only a girdle and no outgrowth.[VSAO]" xsd:string {date_retrieved="2012-09-06", external_class="VSAO:0000214", ontology="VSAO", source="Curator"}
property_value: UBPROP:0000012 "note that the FMA uses the term 'limb' to refer to the entire appendage complex (free limb plus girdle region)" xsd:string {external_ontology="FMA"}
creation_date: 2012-04-23T10:46:51Z

[Term]
id: UBERON:0010708
name: pectoral complex
namespace: uberon
def: "Appendage girdle complex that when present, encompasses the pectoral appendicular skeleton and the pectoral girdle." [VSAO:0000213]
subset: pheno_slim
synonym: "pectoral appendage/girdle complex" EXACT [VSAO:0000213]
synonym: "pectoral girdle plus anterior limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "pectoral girdle plus pectoral limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "upper limb" RELATED INCONSISTENT [FMA:7183]
synonym: "upper limb and pectoral girdle" RELATED HUMAN_PREFERRED [https://orcid.org/0000-0002-6601-2165]
synonym: "upper limb and shoulder" RELATED [https://orcid.org/0000-0002-6601-2165]
xref: EMAPA:37860 {source="MA:th"}
xref: FMA:7183
xref: SCTID:110716002
xref: VSAO:0000213
is_a: UBERON:0010707 ! appendage girdle complex
intersection_of: UBERON:0010707 ! appendage girdle complex
intersection_of: has_part UBERON:0001421 ! pectoral girdle region
relationship: has_part UBERON:0001421 ! pectoral girdle region
relationship: has_skeleton UBERON:0012475 ! skeleton of pectoral complex
relationship: part_of UBERON:0000153 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! anterior region of body
property_value: UBPROP:0000001 "Appendage girdle complex that when present, encompasses the pectoral appendage and half of the pectoral girdle.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000213", ontology="VSAO", source="VSAO:MAH"}
property_value: UBPROP:0000012 "note that the FMA uses the terms 'upper limb' and 'lower limb' to refer to the entire appendage complex (free limb plus girdle region)" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0010709
name: pelvic complex
namespace: uberon
def: "Appendage girdle complex that when present, encompasses the pelvic appendicular skeleton and the pelvic girdle." [VSAO:0000215]
subset: pheno_slim
synonym: "lower limb" RELATED INCONSISTENT [FMA:7184]
synonym: "lower limb and pelvic girdle" RELATED HUMAN_PREFERRED [https://orcid.org/0000-0002-6601-2165]
synonym: "lower limb and pelvis" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "pelvic appendage/girdle complex" EXACT [VSAO:0000215]
synonym: "pelvic girdle plus pelvic limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165]
synonym: "pelvic girdle plus posterior limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165]
xref: EMAPA:37863 {source="MA:th"}
xref: FMA:7184
xref: SCTID:416631005
xref: VSAO:0000215
is_a: UBERON:0010707 ! appendage girdle complex
intersection_of: UBERON:0010707 ! appendage girdle complex
intersection_of: has_part UBERON:0001271 ! pelvic girdle region
relationship: has_part UBERON:0001271 ! pelvic girdle region
relationship: has_skeleton UBERON:0012476 ! skeleton of pelvic complex
relationship: part_of UBERON:0000154 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! posterior region of body
property_value: RO:0002171 UBERON:0010708
property_value: UBPROP:0000001 "Appendage girdle complex that when present, encompasses the pelvic appendage and the pelvic girdle.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000215", ontology="VSAO", source="VSAO:MAH"}
property_value: UBPROP:0000012 "note that the FMA uses the terms 'upper limb' and 'lower limb' to refer to the entire appendage complex (free limb plus girdle region). Note the MA class 'hindlimb' may also belong here" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0010719
name: girdle skeleton
namespace: uberon
def: "The subdivision of the skeleton of either the pectoral or pelvic girdle." [https://orcid.org/0000-0002-6601-2165]
synonym: "skeleton of girdle" EXACT []
xref: AAO:0010686
xref: VSAO:0000302
is_a: UBERON:0010912 ! subdivision of skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: skeleton_of UBERON:0007823 ! appendage girdle region
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0002091 ! appendicular skeleton
relationship: part_of UBERON:0007823 ! appendage girdle region
relationship: proximally_connected_to UBERON:0002090 ! postcranial axial skeleton
relationship: skeleton_of UBERON:0007823 ! appendage girdle region
property_value: UBPROP:0000001 "Skeletal subdivision that is part of the appendage girdle region.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000302", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070"}
property_value: UBPROP:0000002 "relationship type change: subclass skeletal subdivision (VSAO:0000042) CHANGED TO: part_of subdivision of skeleton (UBERON:0010912)[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000302", ontology="VSAO"}
property_value: UBPROP:0000002 "relationship type change: subclass skeletal subdivision (VSAO:0000042) CHANGED TO: proximally_connected_to subdivision of skeleton (UBERON:0010912)[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000302", ontology="VSAO"}

[Term]
id: UBERON:0010740
name: bone of appendage girdle complex
namespace: uberon
def: "A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle)." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003]
subset: pheno_slim
synonym: "bone of extended limb/fin region" RELATED [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003]
synonym: "limb bone" RELATED [MA:0000688, UBERONREF:0000003]
xref: EMAPA:35494
xref: MA:0000688
is_a: UBERON:0001474 ! bone element
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0010707 ! appendage girdle complex
relationship: contributes_to_morphology_of UBERON:0002091 ! appendicular skeleton
relationship: part_of UBERON:0002091 {notes="UBERONREF:0000003"} ! appendicular skeleton
relationship: part_of UBERON:0010707 ! appendage girdle complex

[Term]
id: UBERON:0010741
name: bone of pectoral complex
namespace: uberon
def: "A bone that is part of a pectoral complex. Examples: scapula, manus phalanx, any carpal bone, any bone of the pectoral fin." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003]
subset: pheno_slim
synonym: "bone of forelimb or pectoral fin or pectoral girdle" RELATED [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003]
synonym: "forelimb bone" RELATED [MA:0000612, UBERONREF:0000003]
synonym: "wing bone" NARROW SENSU [UBERONREF:0000003]
xref: EMAPA:32623
xref: EMAPA:35933
xref: MA:0000612
is_a: UBERON:0010740 ! bone of appendage girdle complex
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0010708 ! pectoral complex
relationship: part_of UBERON:0010708 ! pectoral complex
property_value: editor_note "considering adding pectoral and pelvic complex skeleton classes" xsd:string
property_value: UBPROP:0000012 "note that the MA class includes girdle parts so it belongs here;" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0010742
name: bone of pelvic complex
namespace: uberon
def: "A bone that is part of a pelvic complex. Examples: pubis, ischium, fot phalanx, any tarsal bone, any bone of the pelvic fin or girdle." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003]
subset: pheno_slim
synonym: "hindlimb bone" RELATED [MA:0000660, UBERONREF:0000003]
xref: EMAPA:32633
xref: EMAPA:35934
xref: MA:0000660
is_a: UBERON:0010740 {source="MA"} ! bone of appendage girdle complex
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0010709 ! pelvic complex
relationship: part_of UBERON:0010709 ! pelvic complex
property_value: UBPROP:0000012 "the MA class called 'hindlimb bone' belongs here, as it includes bones in the pelvic girdle" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0010890
name: pelvic complex muscle
namespace: uberon
def: "Muscles of the pelvic girdle, hindlimb or pelvic fin." [https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "lower limb muscle" RELATED INCONSISTENT [FMA:9622]
synonym: "muscle of lower limb" RELATED INCONSISTENT [FMA:9622]
synonym: "muscle of pelvic girdle and leg" RELATED []
synonym: "pelvic girdle and hind limb muscles" EXACT [AAO:0000218]
synonym: "pelvic girdle or hind limb muscle" NARROW [https://orcid.org/0000-0002-6601-2165]
synonym: "pelvic girdle or posterior limb muscle" NARROW [https://orcid.org/0000-0002-6601-2165]
xref: AAO:0000218
xref: EMAPA:32634
xref: FMA:9622
xref: MA:0000663
is_a: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0010709 ! pelvic complex
relationship: part_of UBERON:0014792 {source="prolog"} ! musculature of pelvic complex
property_value: UBPROP:0000001 "Muscles of the pelvic girdle, thigh, leg (crus), and foot (pes).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000218", ontology="AAO", source="AAO:EJS"}

[Term]
id: UBERON:0010891
name: pectoral complex muscle
namespace: uberon
def: "A muscle of a pectoral girdle, pectoral fin or anterior limb." [https://orcid.org/0000-0002-6601-2165]
synonym: "muscle of pectoral girdle and limb" RELATED []
synonym: "muscle of pectoral girdle and wing" NARROW SENSU [NCBITaxon:8782]
synonym: "muscle of upper limb" NARROW INCONSISTENT [FMA:9621]
synonym: "pectoral girdle and fore limb muscles" EXACT [AAO:0010687]
synonym: "upper limb muscle" NARROW INCONSISTENT [FMA:9621]
xref: AAO:0010687
xref: EMAPA:32624
xref: FMA:9621
xref: MA:0000615
is_a: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0010708 ! pectoral complex
relationship: part_of UBERON:0014793 {source="prolog"} ! musculature of pectoral complex
property_value: editor_note "the MA class belongs here, based on its current child classes" xsd:string
property_value: UBPROP:0000001 "Muscles of the pectoral girdle, arm, forearm, and hand (brachium, antebrachium, manus respectively).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010687", ontology="AAO", source="AAO:EJS"}

[Term]
id: UBERON:0010899
name: synchronous hermaphroditic organism
namespace: uberon
def: "Hermaphroditic organism that produces both male and female gametes at the same time." [CARO:0000046]
synonym: "serially hermaphroditic organism" RELATED [CARO:0000046]
synonym: "simultaneous hermaphroditic organism" RELATED [https://orcid.org/0000-0002-6601-2165]
xref: AAO:0010046
xref: BILA:0000046
xref: CARO:0000046
xref: HAO:0000046
xref: TADS:0000609
is_a: UBERON:0007197 {source="CARO"} ! hermaphroditic organism
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: has_part UBERON:0000473 ! testis
intersection_of: has_part UBERON:0000992 ! ovary
relationship: has_part UBERON:0000473 ! testis
relationship: has_part UBERON:0000992 ! ovary

[Term]
id: UBERON:0010912
name: subdivision of skeleton
namespace: uberon
def: "Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003]
subset: non_informative
synonym: "skeletal subdivision" EXACT [VSAO:0000042]
synonym: "subdivision of skeleton (in vivo)" RELATED [FMA:23879]
xref: FMA:23879
xref: SCTID:129140006
xref: VSAO:0000042
is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision
relationship: part_of UBERON:0000075 {source="UBERONREF:0000003"} ! subdivision of skeletal system
relationship: part_of UBERON:0004288 {source="VSAO"} ! skeleton
property_value: UBPROP:0000001 "Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000042", notes="incorrect", ontology="VSAO", source="VSAO:curator"}

[Term]
id: UBERON:0010913
name: vertebral element
namespace: uberon
alt_id: UBERON:0015005
def: "Skeletal element that forms around the notochord and is part of the vertebral column." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/294, VSAO:0000184]
synonym: "vertebra element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern]
synonym: "vertebra endochondral element" NARROW [https://github.com/obophenotype/uberon/issues/82]
synonym: "vertebra skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern]
synonym: "vertebral endochondral element" NARROW [https://github.com/obophenotype/uberon/issues/82]
xref: VHOG:0001143
xref: VSAO:0000184
is_a: UBERON:0004765 {source="VSAO", source="https://github.com/obophenotype/uberon/issues/82"} ! skeletal element
relationship: develops_from UBERON:0003089 {source="cjm"} ! sclerotome
property_value: curator_notes "we include a distinct subclass for bony vertebra" xsd:string
property_value: UBPROP:0000003 "In contrast to lampreys and jawed vertebrates, hagfishes were thought to lack vertebrae. Now, long overlooked vertebral rudiments have been analysed in hagfish, suggesting that vertebrae existed in the last common ancestor of all vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001143", ontology="VHOG", source="DOI:10.1016/j.cub.2011.07.014 Janvier P, Comparative anatomy: all vertebrates do have vertebrae. Current Biology (2011)", source="http://bgee.unil.ch/"}
property_value: UBPROP:0000007 "vertebral" xsd:string
property_value: UBPROP:0000008 "Typically an endochondral element, in salamanders there is an argument that vertebral development is perichondral and not preformed in cartilage" xsd:string

[Term]
id: UBERON:0010959
name: craniocervical muscle
namespace: uberon
def: "Any muscle organ that is part of either the head or the neck." [http://orcid.org/0000-0002-6601-2165]
synonym: "muscle of head and neck" RELATED []
synonym: "muscle of head or neck" EXACT []
xref: NCIT:C32716
xref: UMLS:C0448281 {source="ncithesaurus:Head_and_Neck_Muscle"}
is_a: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0007811 ! craniocervical region
relationship: part_of UBERON:0008229 {source="prolog"} ! craniocervical region musculature

[Term]
id: UBERON:0011004
name: pharyngeal arch cartilage
namespace: uberon
def: "A cartilage element that is part of a splanchnocranium." [OBOL:automatic]
subset: efo_slim
synonym: "pharyngeal arch cartilages" EXACT OMO:0003004 [ZFA:0001460]
synonym: "splanchnocranium cartilage" EXACT [ZFA:0001460]
xref: BTO:0006051 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: EFO:0003689
xref: TAO:0001460
xref: ZFA:0001460
is_a: UBERON:0003933 {source="ZFA"} ! cranial cartilage
intersection_of: UBERON:0007844 ! cartilage element
intersection_of: part_of UBERON:0008895 ! splanchnocranium
relationship: develops_from UBERON:0002539 ! pharyngeal arch
relationship: part_of UBERON:0008895 {source="ZFA"} ! splanchnocranium

[Term]
id: UBERON:0011085
name: palatoquadrate arch
namespace: uberon
def: "The dorsal portion of the first pharyngeal arch, comprising the upper jaw[ZFIN,VHOG]." [https://github.com/obophenotype/uberon/issues/153, VHOG:0000511]
subset: efo_slim
synonym: "dorsal mandibular arch" RELATED [VHOG:0000511]
synonym: "dorsal pharyngeal arch 1" RELATED [VHOG:0000511]
synonym: "dorsal visceral arch 1" EXACT [ZFA:0001272]
synonym: "dorsal visceral arch 1" RELATED [VHOG:0000511]
synonym: "palatoquadrate arch" RELATED [VHOG:0000511]
synonym: "upper jaw" RELATED [VHOG:0000511]
synonym: "upper pharyngeal jaw" EXACT [ZFA:0001272]
synonym: "upper pharyngeal jaw" RELATED [VHOG:0000511]
xref: EFO:0003659
xref: TAO:0001272
xref: VHOG:0000511
xref: ZFA:0001272
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0010912 {source="cjm"} ! subdivision of skeleton
relationship: develops_from UBERON:0004362 ! pharyngeal arch 1
relationship: part_of UBERON:0003277 ! skeleton of upper jaw
relationship: part_of UBERON:0008895 {source="VHOG"} ! splanchnocranium
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly
property_value: UBPROP:0000003 "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000511", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0011090
name: skeleton of right pelvic girdle
namespace: uberon
def: "A skeleton of pelvic girdle that is part of a right pelvic girdle region." [OBOL:automatic]
xref: FMA:87593
is_a: UBERON:0007832 ! pelvic girdle skeleton
intersection_of: UBERON:0007832 ! pelvic girdle skeleton
intersection_of: part_of UBERON:0011092 ! right pelvic girdle region
relationship: part_of UBERON:0011092 ! right pelvic girdle region

[Term]
id: UBERON:0011091
name: skeleton of left pelvic girdle
namespace: uberon
def: "A skeleton of pelvic girdle that is part of a left pelvic girdle region." [OBOL:automatic]
xref: FMA:87594
is_a: UBERON:0007832 ! pelvic girdle skeleton
intersection_of: UBERON:0007832 ! pelvic girdle skeleton
intersection_of: part_of UBERON:0011093 ! left pelvic girdle region
relationship: part_of UBERON:0011093 ! left pelvic girdle region

[Term]
id: UBERON:0011092
name: right pelvic girdle region
namespace: uberon
def: "A pelvic girdle region that is in the right side of a multicellular organism." [OBOL:automatic]
synonym: "right pelvic girdle" EXACT INCONSISTENT [FMA:16582]
xref: FMA:16582
is_a: UBERON:0001271 ! pelvic girdle region
intersection_of: UBERON:0001271 ! pelvic girdle region
intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism
relationship: has_skeleton UBERON:0011090 ! skeleton of right pelvic girdle
relationship: in_right_side_of UBERON:0000468 ! multicellular organism
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0011093
name: left pelvic girdle region
namespace: uberon
def: "A pelvic girdle region that is in the left side of a multicellular organism." [OBOL:automatic]
synonym: "left pelvic girdle" EXACT INCONSISTENT [FMA:16583]
xref: FMA:16583
is_a: UBERON:0001271 ! pelvic girdle region
intersection_of: UBERON:0001271 ! pelvic girdle region
intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism
relationship: has_skeleton UBERON:0011091 ! skeleton of left pelvic girdle
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI

[Term]
id: UBERON:0011094
name: vertebra cartilage element
namespace: uberon
def: "The cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, http://orcid.org/0000-0002-6601-2165, VSAO:0000184]
synonym: "vertebral cartilage condensation" EXACT [VHOG:0000584]
xref: EMAPA:32669
xref: VHOG:0000584
is_a: UBERON:0007844 ! cartilage element
is_a: UBERON:0010913 ! vertebral element
intersection_of: UBERON:0010913 ! vertebral element
intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue
relationship: develops_from UBERON:0011095 ! vertebra pre-cartilage condensation
relationship: has_potential_to_develop_into UBERON:0002412 ! vertebra
property_value: RO:0002175 NCBITaxon:7764 {notes="vertebra-like cartilage in hagfish are homologous to gnathostome vertebrae. mesenchymal cells express Pax1/9 and Twist", source="PMC3157150"}
property_value: UBPROP:0000012 "This class is a superclass of individual vertebral cartilage condensations. Note that EHDAA2 represents these as condensation groups" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0011095
name: vertebra pre-cartilage condensation
namespace: uberon
def: "The pre-cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, http://orcid.org/0000-0002-6601-2165, VSAO:0000184]
synonym: "vertebral pre-cartilage condensation" EXACT [VHOG:0000582]
xref: EMAPA:32671
xref: VHOG:0000582
is_a: UBERON:0010913 ! vertebral element
intersection_of: UBERON:0010913 ! vertebral element
intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation
relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation
relationship: has_potential_to_develop_into UBERON:0002412 ! vertebra

[Term]
id: UBERON:0011107
name: synovial joint of pelvic girdle
namespace: uberon
def: "A synovial joint that is part of a pelvic girdle region." [OBOL:automatic]
synonym: "joint of pelvic girdle" EXACT []
synonym: "pelvic girdle joint" EXACT [FMA:35173]
xref: FMA:35173
xref: NCIT:C32890
xref: UMLS:C0827002 {source="ncithesaurus:Joint_of_the_Pelvic_Girdle"}
is_a: UBERON:0002217 ! synovial joint
is_a: UBERON:0008114 ! joint of girdle
intersection_of: UBERON:0002217 ! synovial joint
intersection_of: part_of UBERON:0001271 ! pelvic girdle region
relationship: connects UBERON:0007830 ! pelvic girdle bone/zone
relationship: part_of UBERON:0001271 ! pelvic girdle region

[Term]
id: UBERON:0011108
name: synovial joint of pectoral girdle
namespace: uberon
def: "A synovial joint that is part of a pectoral girdle region." [OBOL:automatic]
synonym: "joint of shoulder girdle" EXACT []
synonym: "pectoral girdle joint" EXACT [FMA:35243]
xref: FMA:35243
xref: SCTID:303080001
is_a: UBERON:0002217 ! synovial joint
is_a: UBERON:0008114 ! joint of girdle
intersection_of: UBERON:0002217 ! synovial joint
intersection_of: part_of UBERON:0001421 ! pectoral girdle region
relationship: connects UBERON:0007829 ! pectoral girdle bone
relationship: part_of UBERON:0001421 ! pectoral girdle region
property_value: UBPROP:0000012 "in FMA, these are part of the bony pectoral girdle" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0011134
name: nonsynovial joint
namespace: uberon
def: "Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis." [FMA:7491]
synonym: "solid joint" EXACT [FMA:7491]
xref: FMA:7491
is_a: UBERON:0000982 {source="FMA"} ! skeletal joint

[Term]
id: UBERON:0011137
name: axial skeletal system
namespace: uberon
def: "Subdivision of the skeletal system which consists of the axial skeleton plus associated joints." [https://orcid.org/0000-0002-6601-2165]
xref: FMA:7483
is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system
relationship: has_part UBERON:0000982 ! skeletal joint
property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton" xsd:anyURI

[Term]
id: UBERON:0011138
name: postcranial axial skeletal system
namespace: uberon
def: "Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints." [https://github.com/obophenotype/uberon/issues/44, https://orcid.org/0000-0002-6601-2165]
synonym: "axial skeletal system" BROAD [https://github.com/obophenotype/uberon/wiki/The-axial-skeleton]
synonym: "post-cranial axial skeletal system" EXACT []
xref: FMA:302077
is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system
relationship: develops_from UBERON:0003089 {source="cjm"} ! sclerotome
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton" xsd:anyURI

[Term]
id: UBERON:0011143
name: upper urinary tract
namespace: uberon
def: "Subdivision of urinary system which consists of the kidney and the ureters." [FMA:45658]
subset: human_reference_atlas
subset: pheno_slim
xref: FMA:45658
xref: galen:UpperUrinaryTract
xref: NCIT:C61107
xref: SCTID:181413006
is_a: UBERON:0011216 ! organ system subdivision
is_a: UBERON:0015212 ! lateral structure
relationship: has_part UBERON:0000056 ! ureter
relationship: has_part UBERON:0002113 ! kidney
relationship: in_lateral_side_of UBERON:0001008 {source="FMA-abduced-lr"} ! renal system
relationship: part_of UBERON:0001008 {source="FMA"} ! renal system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0011148
name: submucosal gland
namespace: uberon
def: "Gland of the lamina epithelialis mucosae which perforate the lamina muscularis, with their adenomeres located in the submucosal connective tissue." [BTO:0003751, Wikipedia:Submucosal_glands]
xref: BTO:0003751
xref: EMAPA:37970 {source="MA:th"}
xref: Wikipedia:Submucosal_glands
is_a: UBERON:0000414 ! mucous gland
intersection_of: UBERON:0000414 ! mucous gland
intersection_of: located_in UBERON:0000009 ! submucosa
relationship: continuous_with UBERON:0003350 {notes="perforates"} ! epithelium of mucosa
relationship: located_in UBERON:0000009 ! submucosa

[Term]
id: UBERON:0011156
name: facial skeleton
namespace: uberon
def: "Subdivision of skull that consists of the facial bones." [http://www.bartleby.com/107/37.html, https://orcid.org/0000-0002-6601-2165, MP:0005274, Wikipedia:Facial_skeleton]
subset: pheno_slim
synonym: "facial bone" RELATED [MA:0000318]
synonym: "facial skeleton" EXACT [FMA:53673]
synonym: "ossa facialia" RELATED OMO:0003011 [Wikipedia:Facial_skeleton]
synonym: "ossa faciei" RELATED OMO:0003011 [Wikipedia:Facial_skeleton]
synonym: "viscerocranium" RELATED INCONSISTENT [MA:0000318]
xref: EHDAA2:0002206
xref: EHDAA:8361
xref: EMAPA:18022
xref: FMA:53673
xref: MA:0000318
xref: Wikipedia:Facial_skeleton
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0011158 {source="FMA"} ! primary subdivision of skull
relationship: part_of UBERON:0001456 {source="FMA"} ! face
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg" xsd:anyURI

[Term]
id: UBERON:0011158
name: primary subdivision of skull
namespace: uberon
def: "The skull can be divided into two: the neurocranium and the facial skeleton." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
synonym: "skull subdivision" EXACT [FMA:54964]
synonym: "subdivision of skull" EXACT [FMA:54964]
xref: FMA:54964
is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system
relationship: part_of UBERON:0003129 ! skull

[Term]
id: UBERON:0011159
name: primary subdivision of cranial skeletal system
namespace: uberon
subset: non_informative
is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system
relationship: part_of UBERON:0010323 ! cranial skeletal system

[Term]
id: UBERON:0011164
name: neurocranium bone
namespace: uberon
def: "A bone that is part of a neurocranium [Automatically generated definition]." [OBOL:automatic]
synonym: "chondrocranium bone" EXACT [MA:0001478]
xref: EMAPA:35238
xref: MA:0001478
xref: SCTID:120229002
is_a: UBERON:0003457 ! head bone
is_a: UBERON:0004766 ! cranial bone
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0001703 ! neurocranium
relationship: part_of UBERON:0001703 ! neurocranium

[Term]
id: UBERON:0011171
name: joint connecting upper and lower jaws
namespace: uberon
def: "Synovial joint that articulates bones of upper and lower jaw." [http://evolution.berkeley.edu/evolibrary/article/evograms_05, https://orcid.org/0000-0002-6601-2165]
synonym: "craniomandibular joint" NARROW []
synonym: "jaw joint" BROAD []
xref: NCIT:C32888
is_a: UBERON:0002217 {source="abduced"} ! synovial joint
intersection_of: UBERON:0000982 ! skeletal joint
intersection_of: connects UBERON:0003277 ! skeleton of upper jaw
intersection_of: connects UBERON:0003278 ! skeleton of lower jaw
relationship: connects UBERON:0003277 ! skeleton of upper jaw
relationship: connects UBERON:0003278 ! skeleton of lower jaw
property_value: UBPROP:0000008 "Some synapsids retained two pairs of jaw joints - quadrate-articular and tempero-mandibular, but this unusual paired condition did not last long" xsd:string {source="http://evolution.berkeley.edu"}

[Term]
id: UBERON:0011185
name: gastrointestinal sphincter
namespace: uberon
def: "A sphincter muscle that is part of the gastrointestinal system." [OBOL:automatic]
xref: NCIT:C32669
xref: UMLS:C1517464 {source="ncithesaurus:Gastrointestinal_Sphincter"}
is_a: UBERON:0004590 ! sphincter muscle
is_a: UBERON:0013765 ! digestive system element
intersection_of: UBERON:0004590 ! sphincter muscle
intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system
relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system

[Term]
id: UBERON:0011189
name: lamina propria of large intestine
namespace: uberon
def: "A lamina propria that is part of a large intestine." [OBOL:automatic]
subset: human_reference_atlas
synonym: "lamina propria of mucosa of large intestine" EXACT [FMA:15654]
synonym: "large intestinal lamina propria" EXACT []
synonym: "large intestine lamina propria" EXACT [FMA:15654]
xref: FMA:15654
xref: NCIT:C49298
xref: UMLS:C1708644 {source="ncithesaurus:Large_Intestinal_Lamina_Propria"}
is_a: UBERON:0004780 ! gastrointestinal system lamina propria
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0000059 ! large intestine
relationship: part_of UBERON:0001207 {source="FMA"} ! mucosa of large intestine
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0011198
name: muscle layer of large intestine
namespace: uberon
def: "A muscle layer that is part of a large intestine." [OBOL:automatic]
synonym: "muscular coat of large intestine" EXACT [FMA:14971]
synonym: "muscular layer of large intestine" EXACT [FMA:14971]
synonym: "muscularis externa of large intestine" EXACT [FMA:14971]
synonym: "tunica muscularis intestini crassi" EXACT OMO:0003011 [FMA:TA]
xref: FMA:14971
xref: NCIT:C32927
xref: UMLS:C0734205 {source="ncithesaurus:Large_Intestinal_Muscular_Coat"}
is_a: UBERON:0012367 ! muscle layer of intestine
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0000059 ! large intestine
relationship: part_of UBERON:0001169 {source="FMA"} ! wall of large intestine

[Term]
id: UBERON:0011201
name: muscle layer of small intestine
namespace: uberon
def: "A muscle layer that is part of a small intestine." [OBOL:automatic]
synonym: "muscular coat of small intestine" EXACT [FMA:14932]
synonym: "muscular layer of small intestine" EXACT [FMA:14932]
synonym: "muscularis externa of small intestine" EXACT [FMA:14932]
synonym: "small intestine muscularis propria" EXACT [FMA:14932]
synonym: "tunica muscularis (intestinum tenue)" EXACT [FMA:14932]
synonym: "tunica muscularis intestini tenuis" EXACT OMO:0003011 [FMA:TA]
xref: FMA:14932
xref: NCIT:C33569
xref: SCTID:362145004
xref: UMLS:C0227269 {source="ncithesaurus:Small_Intestinal_Muscular_Coat"}
is_a: UBERON:0012367 ! muscle layer of intestine
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0001168 {source="FMA"} ! wall of small intestine

[Term]
id: UBERON:0011215
name: central nervous system cell part cluster
namespace: uberon
def: "A multi cell part structure that is part of a central nervous system." [OBOL:automatic]
subset: upper_level
synonym: "cell part cluster of neuraxis" EXACT [FMA:83143]
synonym: "neuraxis layer" EXACT [FMA:83143]
xref: FMA:83143
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0005162 ! multi cell part structure
intersection_of: UBERON:0005162 ! multi cell part structure
intersection_of: part_of UBERON:0001017 ! central nervous system
relationship: part_of UBERON:0001017 ! central nervous system

[Term]
id: UBERON:0011216
name: organ system subdivision
namespace: uberon
def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165]
subset: common_anatomy
subset: human_reference_atlas
subset: upper_level
xref: FBbt:00007330 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
xref: FMA:67509
xref: SCTID:91690000
is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure
relationship: part_of UBERON:0000467 ! anatomical system
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0011222
name: intra-ocular muscle
namespace: uberon
synonym: "intrinsic muscle of eyeball" EXACT []
synonym: "intrinsic ocular muscle" EXACT [EMAPA:18808]
xref: AAO:0010038
xref: EMAPA:18808
xref: FMA:49150
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0004277 ! eye muscle
relationship: part_of UBERON:0003386 {source="EMAPA"} ! smooth muscle of eye
property_value: UBPROP:0000001 "Muscles within the eye (bulbus oculi).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010038", ontology="AAO", source="AAO:EJS"}

[Term]
id: UBERON:0011233
name: synovial membrane of synovial tendon sheath
namespace: uberon
def: "Synovial sac which surrounds parts of one or more tendons. Examples: synovial tendon sheath of manual digit 2, radial bursa." [FMA:45087, Wikipedia:Synovial_sheath]
comment: Alternate def: A synovial sheath is a layer of a tendon sheath containing tendons in the hand and foot. They lie internal to the fibrous tendon sheaths. An example is the common synovial sheath for the flexor tendons. [Wikipedia:Synovial_sheath]
synonym: "synovium" BROAD [BTO:0001823]
xref: BTO:0001823
xref: FMA:40878
xref: Wikipedia:Synovial_sheath
is_a: UBERON:0007616 ! layer of synovial tissue
intersection_of: UBERON:0007616 ! layer of synovial tissue
intersection_of: bounding_layer_of UBERON:0000304 ! tendon sheath
relationship: bounding_layer_of UBERON:0000304 ! tendon sheath
relationship: part_of UBERON:0000304 ! tendon sheath

[Term]
id: UBERON:0011234
name: fibrous membrane of synovial tendon sheath
namespace: uberon
xref: FMA:40877
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: bounding_layer_of UBERON:0000304 ! tendon sheath
intersection_of: composed_primarily_of UBERON:0011824 ! fibrous connective tissue
relationship: bounding_layer_of UBERON:0000304 ! tendon sheath
relationship: composed_primarily_of UBERON:0011824 ! fibrous connective tissue
relationship: part_of UBERON:0000304 ! tendon sheath

[Term]
id: UBERON:0011241
name: ethmoid region
namespace: uberon
def: "The most anterior region of the braincase. Provides structural support for peripheral olfactory organ." [http://palaeos.com/vertebrates/bones/braincase/ethmoid.html, UBERONREF:0000007]
xref: AAO:0000986
is_a: UBERON:0034921 ! multi organ part structure
relationship: has_developmental_contribution_from UBERON:0005945 ! neurocranial trabecula
relationship: part_of UBERON:0003112 ! olfactory region
property_value: curator_notes "currently this is not restricted to skeletal elements, unlike UBERONREF:0000007" xsd:string

[Term]
id: UBERON:0011249
name: appendicular skeletal system
namespace: uberon
def: "Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints." [https://orcid.org/0000-0002-6601-2165]
xref: FMA:7484
xref: VHOG:0001666
xref: VSAO:0000306
is_a: UBERON:0000075 ! subdivision of skeletal system
relationship: has_part UBERON:0000982 ! skeletal joint
relationship: has_part UBERON:0002091 ! appendicular skeleton
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Appendages-and-the-appendicular-skeleton" xsd:anyURI
property_value: UBPROP:0000001 "Skeletal system which consists of the appendicular skeleton plus associated joints.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000306", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"}

[Term]
id: UBERON:0011270
name: dorsal trunk
namespace: uberon
def: "The part of the trunk that is in the dorsum[cjm]." [UBERONREF:0000006, Wikipedia:Human_back]
synonym: "back of trunk" EXACT [FMA:25056]
synonym: "dorsal part of trunk" EXACT []
synonym: "dorsum of trunk" EXACT [FMA:25056]
synonym: "trunk back" EXACT [FMA:25056]
xref: EMAPA:35162
xref: FMA:25056
xref: MA:0000020
xref: Wikipedia:Human_back
is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk
relationship: part_of UBERON:0001137 {source="FMA"} ! dorsum
property_value: UBPROP:0000008 "In humans, the subdivision of trunk which is demarcated from the trunk proper by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines, the external surface of the posterior abdominal wall; together with the trunk proper, it constitutes the trunk[FMA]" xsd:string

[Term]
id: UBERON:0011272
name: embryonic skin basal layer
namespace: uberon
synonym: "basal cell layer of skin" RELATED []
synonym: "outer epithelium of body" RELATED [Wikipathways:WP2062]
xref: EHDAA2:0001845
is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium
is_a: UBERON:0010371 ! ecto-epithelium
relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm
relationship: part_of UBERON:0002199 {source="EHDAA2"} ! integument
property_value: editor_note "compare with 'stratum basale of epidermis'. This class is the source for many adult structures - see WP2062. See also: 'enveloping layer of ectoderm'" xsd:string

[Term]
id: UBERON:0011298
name: submucosa of uterine tube
namespace: uberon
def: "The submucous layer of the wall of the uterine tube." [BTO:0002116]
synonym: "submucosa of fallopian tube" EXACT []
synonym: "submucous layer of uterine tube" RELATED [BTO:0002116]
synonym: "tela submucosa tubae uterinae" EXACT OMO:0003011 [BTO:0002116]
synonym: "uterine submucosa" RELATED []
xref: BTO:0002116
xref: SCTID:245489008
is_a: UBERON:0000009 ! submucosa
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0003889 ! fallopian tube
relationship: part_of UBERON:0003889 ! fallopian tube

[Term]
id: UBERON:0011362
name: cranial blood vasculature
namespace: uberon
def: "A blood vasculature that is part of a head." [OBOL:automatic]
synonym: "cranial blood vessel" EXACT [ZFA:0005297]
synonym: "cranial blood vessels" RELATED OMO:0003004 [TAO:0005297]
synonym: "set of blood vessels of head" EXACT []
xref: TAO:0005297
xref: ZFA:0005297
is_a: UBERON:0002200 ! vasculature of head
is_a: UBERON:0004537 ! blood vasculature
intersection_of: UBERON:0004537 ! blood vasculature
intersection_of: part_of UBERON:0000033 ! head
property_value: UBPROP:0000001 "Blood vessel part of cranial vasculature.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005297", ontology="TAO", source="ZFIN:curator"}

[Term]
id: UBERON:0011565
name: lumen of gastrointestinal system
namespace: uberon
synonym: "cavity of digestive tract" EXACT []
synonym: "cavity of gastrointestinal tract" EXACT []
synonym: "gastrointestinal tract lumen" EXACT [FMA:54364]
synonym: "lumen of gastrointestinal tract" EXACT [FMA:54364]
xref: FMA:54364
xref: SCTID:432899004
is_a: UBERON:0002553 ! anatomical cavity
relationship: part_of UBERON:0001007 ! digestive system

[Term]
id: UBERON:0011566
name: lumen of esophagus
namespace: uberon
def: "An anatomical cavity that is part of a esophagus." [OBOL:automatic]
subset: pheno_slim
synonym: "cavity of eosophagus" EXACT []
synonym: "cavity of esophagus" EXACT [FMA:9398]
synonym: "eosophageal cavity" EXACT []
synonym: "eosophageal lumen" EXACT []
synonym: "eosophagus lumen" EXACT []
synonym: "esophageal cavity" EXACT [FMA:9398]
synonym: "esophageal lumen" EXACT [FMA:9398]
synonym: "esophagus lumen" EXACT [FMA:9398]
xref: EMAPA:18380
xref: FMA:9398
xref: SCTID:322648002
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0001043 ! esophagus
relationship: luminal_space_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0011565 {source="FMA"} ! lumen of gastrointestinal system

[Term]
id: UBERON:0011574
name: mesonephric duct lumen
namespace: uberon
def: "A tube lumen that is part of a mesonephric duct." [OBOL:automatic]
synonym: "cavity of nephric duct" RELATED []
synonym: "nephric duct lumen" EXACT [EHDAA2:0001244]
xref: EHDAA2:0001244
is_a: UBERON:0005082 ! tube lumen
intersection_of: UBERON:0005082 ! tube lumen
intersection_of: luminal_space_of UBERON:0003074 ! mesonephric duct
relationship: luminal_space_of UBERON:0003074 ! mesonephric duct
relationship: part_of UBERON:0003074 ! mesonephric duct

[Term]
id: UBERON:0011582
name: paired limb/fin skeleton
namespace: uberon
def: "The collection of all skeletal elements in an individual limb or fin." [https://orcid.org/0000-0002-6601-2165]
subset: homology_grouping
synonym: "limb/fin skeleton" EXACT [VSAO:0000301]
synonym: "skeletal parts of limb/fin" EXACT []
synonym: "skeleton of limb/fin" EXACT []
xref: VSAO:0000301
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0010912 ! subdivision of skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: skeleton_of UBERON:0004708 ! paired limb/fin
relationship: develops_from UBERON:0003081 {source="ISBN:9780878932504"} ! lateral plate mesoderm
relationship: part_of UBERON:0002091 ! appendicular skeleton
relationship: part_of UBERON:0004708 ! paired limb/fin
relationship: skeleton_of UBERON:0004708 ! paired limb/fin
property_value: UBPROP:0000001 "Skeletal subdivision that is part of the paired limb/fin.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000301", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070"}

[Term]
id: UBERON:0011585
name: cell condensation
namespace: uberon
def: "Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995)." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000006]
xref: VSAO:0000006
xref: XAO:0004021
is_a: UBERON:0000061 {source="VSAO"} ! anatomical structure
property_value: editor_note "consider obsoleting, coordinate with VSAO" xsd:string

[Term]
id: UBERON:0011592
name: future upper lip
namespace: uberon
synonym: "upper jaw future lip" EXACT [EHDAA2:0002120]
xref: EHDAA2:0002120
is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium
is_a: UBERON:0003235 ! epithelium of upper jaw
relationship: develops_from UBERON:0004068 {notes="fusion"} ! medial nasal prominence
relationship: develops_from UBERON:0005868 {notes="fusion"} ! maxillary prominence

[Term]
id: UBERON:0011595
name: jaw region
namespace: uberon
def: "A subdivision of the head that corresponds to the jaw skeleton, containing both soft tissue, skeleton and teeth (when present). The jaw region is divided into upper and lower regions." [http://orcid.org/0000-0002-6601-2165]
xref: EMAPA:32905
xref: NCIT:C114916
is_a: UBERON:0000475 ! organism subdivision
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
intersection_of: UBERON:0000475 ! organism subdivision
intersection_of: has_skeleton UBERON:0001708 ! jaw skeleton
relationship: has_skeleton UBERON:0001708 ! jaw skeleton
relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata <vertebrates>
relationship: part_of UBERON:0000165 {source="EMAPA", source="FMA-abduced", source="ZFA-abduced"} ! mouth
property_value: seeAlso "http://eol.org/collections/11578" xsd:anyURI

[Term]
id: UBERON:0011596
name: future lower lip
namespace: uberon
synonym: "lower jaw future lip" EXACT [EHDAA2:0001020]
xref: EHDAA2:0001020
is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium
is_a: UBERON:0003236 ! epithelium of lower jaw
relationship: develops_from UBERON:0005867 {source="Wikipedia:Mandibular_prominence"} ! mandibular prominence

[Term]
id: UBERON:0011597
name: bone of upper jaw
namespace: uberon
def: "Any bone that is part of the upper jaw skeleton. This includes (when present): the maxilla, the quadrate (in some species)." [https://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "upper jaw bone" EXACT []
is_a: UBERON:0012360 ! bone of jaw
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0001709 ! upper jaw region
relationship: part_of UBERON:0003277 ! skeleton of upper jaw
property_value: editor_note "Do not manually classify under here - bones are automatically classified" xsd:string

[Term]
id: UBERON:0011642
name: oral epithelium from ectoderm
namespace: uberon
def: "An epithelium that develops_from a ectoderm and is part of a oral epithelium." [OBOL:automatic]
xref: EHDAA2:0004137
is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium
is_a: UBERON:0002424 ! oral epithelium
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: develops_from UBERON:0000924 ! ectoderm
intersection_of: part_of UBERON:0002424 ! oral epithelium
relationship: develops_from UBERON:0009479 {source="EHDAA2"} ! ectoderm of buccopharyngeal membrane
relationship: part_of UBERON:0002424 ! oral epithelium

[Term]
id: UBERON:0011648
name: jaw muscle
namespace: uberon
subset: efo_slim
subset: pheno_slim
synonym: "mandibular muscle" EXACT [TAO:0000236]
synonym: "mandibular muscles" EXACT OMO:0003004 [TAO:0000236]
xref: AAO:0000247
xref: EFO:0003511
xref: TAO:0000236
xref: XAO:0003269
xref: ZFA:0000236
is_a: UBERON:0002376 ! cranial muscle
relationship: capable_of_part_of GO:0071626 ! mastication

[Term]
id: UBERON:0011676
name: subdivision of organism along main body axis
namespace: uberon
def: "A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column." [https://orcid.org/0000-0002-6601-2165]
subset: upper_level
synonym: "axial subdivision of organism" EXACT []
synonym: "body segment" RELATED []
synonym: "main body segment" RELATED []
is_a: UBERON:0000475 ! organism subdivision
relationship: part_of UBERON:0013701 ! main body axis
property_value: editor_note "Ideally this would be disjoint with analagous class for appendicular axes, but currently 'appendages' like antennae, horns cause a problem" xsd:string

[Term]
id: UBERON:0011677
name: trunk vertebra
namespace: uberon
def: "A vertebra in the trunk region. For tetrapods, includes lumbar and thoracic vertebrae. Excludes caudal/coccygeal vertebra, which are located posteriorly. In tetrapods this includes thoracic, lumbar and sacral vertebrae, and excludes the cervical vertebrae, which are located anteriorly." [UBERONREF:0000006]
subset: pheno_slim
synonym: "presacral vertebra" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "thoracolumbar vertebra" EXACT []
is_a: UBERON:0003463 ! trunk bone
is_a: UBERON:0004247 ! bone of dorsum
is_a: UBERON:0004451 {is_inferred="true"} ! trunk or cervical vertebra
intersection_of: UBERON:0002412 ! vertebra
intersection_of: part_of UBERON:0009568 ! trunk region of vertebral column
relationship: part_of UBERON:0009568 ! trunk region of vertebral column
property_value: UBPROP:0000202 FMA:72066

[Term]
id: UBERON:0011695
name: embryonic cardiovascular system
namespace: uberon
def: "A cardiovascular system that is part of a conceptus." [OBOL:automatic]
synonym: "conceptus cardiovascular system" EXACT []
synonym: "embryonic circulatory system" RELATED []
synonym: "fetal circulatory system" RELATED []
xref: EHDAA2:0000216
xref: FMA:305965
xref: NCIT:C34148
is_a: UBERON:0004535 ! cardiovascular system
intersection_of: UBERON:0004535 ! cardiovascular system
intersection_of: part_of UBERON:0004716 ! conceptus
relationship: part_of UBERON:0004716 ! conceptus

[Term]
id: UBERON:0011757
name: differentiated genital tubercle
namespace: uberon
synonym: "phallus" RELATED [Wikipedia:Primordial_phallus]
synonym: "phallus primordialis" RELATED OMO:0003011 [Wikipedia:Primordial_phallus]
synonym: "primordial phallus" RELATED [Wikipedia:Primordial_phallus]
xref: NCIT:C34274
xref: UMLS:C1514448 {source="ncithesaurus:Primordial_Phallus"}
xref: Wikipedia:Primordial_phallus
is_a: UBERON:0005423 ! developing anatomical structure
union_of: UBERON:0006233 ! female genital tubercle
union_of: UBERON:0006261 ! male genital tubercle
relationship: develops_from UBERON:0005876 ! undifferentiated genital tubercle
relationship: part_of UBERON:0004176 ! external genitalia

[Term]
id: UBERON:0011772
name: lower jaw opening
namespace: uberon
def: "An anatomical space that is part of a bone of lower jaw." [OBOL:automatic]
xref: AAO:0000273
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0004768 ! bone of lower jaw
relationship: luminal_space_of UBERON:0004768 ! bone of lower jaw
relationship: part_of UBERON:0004768 ! bone of lower jaw

[Term]
id: UBERON:0011773
name: upper jaw opening
namespace: uberon
def: "An anatomical space that is part of a bone of upper jaw." [OBOL:automatic]
xref: AAO:0000621
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0011597 ! bone of upper jaw
relationship: luminal_space_of UBERON:0011597 ! bone of upper jaw
relationship: part_of UBERON:0011597 ! bone of upper jaw

[Term]
id: UBERON:0011777
name: nucleus of spinal cord
namespace: uberon
def: "A neural nucleus that is part of the spinal cord." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "spinal cord nucleus" EXACT [FMA:77011]
xref: FMA:77011
is_a: UBERON:0000125 ! neural nucleus
intersection_of: UBERON:0000125 ! neural nucleus
intersection_of: part_of UBERON:0002240 ! spinal cord
relationship: part_of UBERON:0002240 ! spinal cord

[Term]
id: UBERON:0011779
name: nerve of head region
namespace: uberon
def: "A nerve that is part of a head." [OBOL:automatic]
subset: grouping_class
synonym: "cephalic nerve" RELATED []
synonym: "head nerve" RELATED []
is_a: UBERON:0001021 ! nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0000033 ! head

[Term]
id: UBERON:0011814
name: non-neurogenic ectodermal placode
namespace: uberon
def: "Ectodermal placode that does not develop into a component of the nervous system." [http://orcid.org/0000-0002-6601-2165, PMID:11523831]
is_a: UBERON:0005085 {source="cjm"} ! ectodermal placode

[Term]
id: UBERON:0011820
name: atrioventricular region
namespace: uberon
def: "An anatomical junction that divides and overlaps with and atrium and a ventricle in the heart." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
synonym: "atrial ventricular junction" RELATED [GO:0003294]
synonym: "atrioventricular junction" RELATED [FMA:85125, GO:0003294]
synonym: "atrioventricular segment" RELATED [PMID:21234997]
synonym: "AV region" RELATED [PMID:21234997]
synonym: "AV segment" RELATED [PMID:21234997]
xref: EHDAA2:0004149
xref: FMA:85125
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0007651 ! anatomical junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0002081 ! cardiac atrium
intersection_of: connects UBERON:0002082 ! cardiac ventricle
intersection_of: part_of UBERON:0000948 ! heart
relationship: connects UBERON:0002081 ! cardiac atrium
relationship: connects UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0000948 ! heart
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0011821
name: irregular connective tissue
namespace: uberon
def: "Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium." [FMA:20107]
xref: FMA:20107
is_a: UBERON:0002384 {source="FMA"} ! connective tissue

[Term]
id: UBERON:0011822
name: dense irregular connective tissue
namespace: uberon
def: "Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium." [FMA:20109, Wikipedia:Dense_irregular_connective_tissue]
synonym: "irregular dense connective tissue" EXACT []
synonym: "typus irregularis (textus connectivus collagenosus compactus)" EXACT [FMA:20109]
xref: FMA:20109
xref: NCIT:C32882
xref: UMLS:C0738366 {source="ncithesaurus:Irregular_Dense_Connective_Tissue"}
xref: Wikipedia:Dense_irregular_connective_tissue
is_a: UBERON:0011821 {source="FMA"} ! irregular connective tissue
is_a: UBERON:0011823 ! dense connective tissue
intersection_of: UBERON:0011821 ! irregular connective tissue
intersection_of: composed_primarily_of UBERON:0011860 ! collection of collagen fibrils
intersection_of: has_part GO:0071953 ! elastic fiber
relationship: has_part GO:0071953 ! elastic fiber
property_value: UBPROP:0000001 "Tissue characterized by a thick, random arrangement of collagen and elastin fibers with very few cells. The majority of the cells are fibroblasts, but mast cells and macrophages may also be seen. It is found in the dermis, periosteum, perichondrium, capsules of organs and sheaths of nerves and muscles[NCIT]" xsd:string {date_retrieved="2012-08-29", external_class="ncithesaurus:Irregular_Dense_Connective_Tissue", ontology="NCIT"}

[Term]
id: UBERON:0011823
name: dense connective tissue
namespace: uberon
def: "Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets." [Wikipedia:Dense_connective_tissue]
xref: AAO:0000121
xref: NCIT:C32450
xref: UMLS:C1511770 {source="ncithesaurus:Dense_Connective_Tissue"}
xref: Wikipedia:Dense_connective_tissue
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0002384 ! connective tissue
intersection_of: UBERON:0002384 ! connective tissue
intersection_of: composed_primarily_of UBERON:0011860 ! collection of collagen fibrils
disjoint_from: UBERON:0011825 ! loose connective tissue
relationship: composed_primarily_of UBERON:0011860 ! collection of collagen fibrils
property_value: editor_note "our OWL definition states that this is differentiated from other connective tissue types by virtue of the fact that the collage fiber component predominates, as opposed to cells and fluid." xsd:string
property_value: UBPROP:0000001 "Connective tissue in which the fibrous component predominates. The cells, ground substance, and tissue fluid represent a minor component[NCIT]" xsd:string {date_retrieved="2012-08-29", external_class="ncithesaurus:Dense_Connective_Tissue", ontology="NCIT"}

[Term]
id: UBERON:0011824
name: fibrous connective tissue
namespace: uberon
xref: FMA:75634
xref: SCTID:363130003
is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue

[Term]
id: UBERON:0011825
name: loose connective tissue
namespace: uberon
def: "Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue." [FMA:19783]
synonym: "textus connectivus collagenosus laxus" EXACT OMO:0003011 [FMA:19783, FMA:TA]
synonym: "textus connectivus laxus" EXACT OMO:0003011 [FMA:19783, FMA:TA]
xref: FMA:19783
xref: NCIT:C33007
xref: UMLS:C1253917 {source="ncithesaurus:Loose_Connective_Tissue"}
xref: Wikipedia:Loose_connective_tissue
is_a: UBERON:0011821 {source="FMA"} ! irregular connective tissue

[Term]
id: UBERON:0011858
name: acinus of exocrine gland
namespace: uberon
def: "An acinus that is part of a exocrine gland." [OBOL:automatic]
synonym: "exocrine gland acinus" EXACT []
is_a: UBERON:0009842 ! glandular acinus
intersection_of: UBERON:0009842 ! glandular acinus
intersection_of: part_of UBERON:0002365 ! exocrine gland
relationship: part_of UBERON:0002365 ! exocrine gland

[Term]
id: UBERON:0011860
name: collection of collagen fibrils
namespace: uberon
xref: FMA:63212
xref: MESH:D024022
xref: NCIT:C32339
xref: NIF_Subcellular:sao7547390221
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure
relationship: composed_primarily_of GO:0005581 ! collagen trimer
relationship: composed_primarily_of GO:0098643 ! banded collagen fibril
relationship: seeAlso UBERON:0007377
property_value: UBPROP:0000012 "the FMA class specifically refers to ureter" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0011861
name: aorta collagen fibril
namespace: uberon
def: "The connective tissue bundles in the extracellular matrix of aorta tissue that are composed of collagen, and play a role in tissue strength and elasticity." [MP:0011640]
subset: pheno_slim
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0011860 ! collection of collagen fibrils
intersection_of: UBERON:0011860 ! collection of collagen fibrils
intersection_of: part_of UBERON:0004664 ! aorta tunica adventitia
relationship: contributes_to_morphology_of UBERON:0004664 ! aorta tunica adventitia
relationship: part_of UBERON:0004664 ! aorta tunica adventitia

[Term]
id: UBERON:0011862
name: pulmonary collagen fibril
namespace: uberon
def: "The connective tissue bundles in the extracellular matrix of pulmonary tissue that are composed of collagen, and play a role in tissue strength and elasticity." [MP:0011641]
subset: pheno_slim
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0011860 ! collection of collagen fibrils
intersection_of: UBERON:0011860 ! collection of collagen fibrils
intersection_of: part_of UBERON:0002048 ! lung
relationship: contributes_to_morphology_of UBERON:0002048 ! lung
relationship: part_of UBERON:0002048 ! lung

[Term]
id: UBERON:0011863
name: bone collagen fibril
namespace: uberon
def: "The connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity." [MP:0011642]
subset: pheno_slim
is_a: UBERON:0011860 ! collection of collagen fibrils
intersection_of: UBERON:0011860 ! collection of collagen fibrils
intersection_of: part_of UBERON:0001474 ! bone element
relationship: part_of UBERON:0001474 ! bone element

[Term]
id: UBERON:0011864
name: tendon collagen fibril
namespace: uberon
def: "The connective tissue bundles in the extracellular matrix of tendon tissue that are composed of collagen, and play a role in tissue strength and elasticity." [MP:0011643]
subset: pheno_slim
is_a: UBERON:0011860 ! collection of collagen fibrils
intersection_of: UBERON:0011860 ! collection of collagen fibrils
intersection_of: part_of UBERON:0000043 ! tendon
relationship: contributes_to_morphology_of UBERON:0000043 ! tendon
relationship: part_of UBERON:0000043 ! tendon

[Term]
id: UBERON:0011865
name: corneal stroma collagen fibril
namespace: uberon
def: "The connective tissue bundles in the extracellular matrix of corneal stroma that are composed of collagen, and play a role in tissue strength and elasticity." [MP:0011650]
subset: pheno_slim
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0011860 ! collection of collagen fibrils
intersection_of: UBERON:0011860 ! collection of collagen fibrils
intersection_of: part_of UBERON:0001777 ! substantia propria of cornea
relationship: contributes_to_morphology_of UBERON:0001777 ! substantia propria of cornea
relationship: part_of UBERON:0001777 ! substantia propria of cornea

[Term]
id: UBERON:0011878
name: muscle layer of esophagus
namespace: uberon
def: "A muscle layer that is part of a wall of esophagus." [OBOL:automatic]
synonym: "muscle coat of esophagus" EXACT [FMA:62998]
synonym: "muscular coat of oesophagus" EXACT [FMA:62998]
synonym: "muscular layer of oesophagus" EXACT [FMA:62998]
synonym: "tela muscularis (oesophagus)" EXACT OMO:0003011 [FMA:62998, FMA:TA]
synonym: "tunica muscularis esophagi" EXACT OMO:0003011 []
synonym: "tunica muscularis oesophageae" EXACT OMO:0003011 [FMA:TA]
xref: FMA:62998
is_a: UBERON:0018261 ! muscular coat of digestive tract
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: has_part UBERON:0001134 {notes="upper part", source="Wikipedia:Muscular_layer"} ! skeletal muscle tissue
relationship: part_of UBERON:0001096 ! wall of esophagus
property_value: UBPROP:0000010 "In the upper esophagus, part of the externa is skeletal muscle, rather than smooth muscle" xsd:string {source="WP"}

[Term]
id: UBERON:0011892
name: anterior uvea
namespace: uberon
def: "Front (ventral) portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris." [MP:0005194]
subset: pheno_slim
synonym: "anterior part of uveal tract" EXACT []
synonym: "anterior uveal tract" EXACT []
synonym: "anterior vascular layer of the eyeball" EXACT []
synonym: "anterior vascular tunic of the eye" EXACT []
synonym: "ciliary body and iris" RELATED []
synonym: "Haller tunica vascula" EXACT [MP:0005194]
synonym: "tunica vasculosa bulbosa" EXACT [MP:0005194]
synonym: "vasculosa oculi" RELATED [MP:0005194]
synonym: "ventral uveal tract" EXACT []
xref: EMAPA:37417 {source="MA:th"}
xref: SCTID:280656002
is_a: UBERON:0000481 {source="ZFA"} ! multi-tissue structure
is_a: UBERON:0004121 ! ectoderm-derived structure
relationship: contributes_to_morphology_of UBERON:0001768 ! uvea
relationship: contributes_to_morphology_of UBERON:0001801 ! anterior segment of eyeball
relationship: has_part UBERON:0001769 ! iris
relationship: has_part UBERON:0001775 ! ciliary body
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0001768 {source="MP"} ! uvea

[Term]
id: UBERON:0011899
name: epimysium
namespace: uberon
def: "Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous." [Wikipedia:Epimysium]
synonym: "epimysia" RELATED OMO:0003004 [Wikipedia:Epimysium]
synonym: "fascia of muscle organ" EXACT [FMA:9726]
xref: FMA:9726
xref: NCIT:C32527
xref: UMLS:C0504096 {source="ncithesaurus:Epimysium"}
xref: Wikipedia:Epimysium
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue
relationship: bounding_layer_of UBERON:0014892 ! skeletal muscle organ, vertebrate
relationship: continuous_with UBERON:0000043 ! tendon
relationship: part_of UBERON:0001134 {source="FMA"} ! skeletal muscle tissue
property_value: UBPROP:0000009 "The Epimysium also protects muscles from friction against other muscles and bones" xsd:string

[Term]
id: UBERON:0011919
name: yolk sac blood island
namespace: uberon
def: "Masses of developing blood cells attached to endothelium in the yolk sac." [MP:0011204]
subset: pheno_slim
synonym: "visceral yolk sac blood island" EXACT [MP:0011204]
synonym: "yolk sac blood islands" EXACT [EHDAA2:0000177]
xref: EHDAA2:0000177
xref: EMAPA:16115
is_a: UBERON:0000478 ! extraembryonic structure
is_a: UBERON:0003061 ! blood island
intersection_of: UBERON:0003061 ! blood island
intersection_of: part_of UBERON:0003316 ! mesenchyme of yolk sac
relationship: develops_from UBERON:0003316 {source="EHDAA2"} ! mesenchyme of yolk sac
relationship: part_of UBERON:0003316 ! mesenchyme of yolk sac

[Term]
id: UBERON:0011921
name: connecting stalk blood islands
namespace: uberon
synonym: "blood island of umbilical vesicle" EXACT [Wikipedia:Blood_island]
synonym: "insula sanguinea vesiculae umbilicalis" EXACT [Wikipedia:Blood_island]
xref: EHDAA2:0003242
is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle
is_a: UBERON:0010303 ! extraembryonic epithelium
is_a: UBERON:0012275 ! meso-epithelium
relationship: develops_from UBERON:0005667 {source="EHDAA2"} ! connecting stalk mesoderm
relationship: part_of UBERON:0002331 {source="EHDAA2"} ! umbilical cord
property_value: UBPROP:0000012 "in EHDAA2 gives rise to connecting stalk blood vessels and extraembryonic umbilical vessels" xsd:string {external_ontology="EHDAA2"}

[Term]
id: UBERON:0011953
name: stomach glandular region
namespace: uberon
def: "A region of the stomach that is lined with glandular epithelium." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "glandular stomach" RELATED []
xref: EMAPA:17623
xref: MA:0001613
xref: NCIT:C77661
xref: SCTID:27633001
xref: UMLS:C0227197 {source="ncithesaurus:Glandular_Stomach"}
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0009870 ! zone of stomach
intersection_of: UBERON:0009870 ! zone of stomach
intersection_of: has_part UBERON:0006924 ! stomach glandular epithelium
relationship: has_part UBERON:0006924 ! stomach glandular epithelium
property_value: editor_note "as currently defined, this would include the cardiac antrum; however, the intent may be to exclude the cardiac glands and in mice for this to be part of the region distal to the margo plicatus" xsd:string

[Term]
id: UBERON:0011955
name: left hepatic vein
namespace: uberon
def: "A hepatic vein that is part of a left lobe of liver." [OBOL:automatic]
subset: human_reference_atlas
xref: EMAPA:37164 {source="MA:th"}
xref: FMA:14339
xref: MA:0003032
xref: SCTID:55188000
is_a: UBERON:0001143 ! hepatic vein
intersection_of: UBERON:0001143 ! hepatic vein
intersection_of: part_of UBERON:0001115 ! left lobe of liver
relationship: part_of UBERON:0001115 ! left lobe of liver
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0011956
name: right hepatic vein
namespace: uberon
def: "A hepatic vein that is part of a right lobe of liver." [OBOL:automatic]
subset: human_reference_atlas
xref: EMAPA:37377 {source="MA:th"}
xref: FMA:14338
xref: MA:0003034
xref: SCTID:18135006
is_a: UBERON:0001143 ! hepatic vein
intersection_of: UBERON:0001143 ! hepatic vein
intersection_of: part_of UBERON:0001114 ! right lobe of liver
relationship: part_of UBERON:0001114 ! right lobe of liver
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0011997
name: coelom
namespace: uberon
def: "The aggregate of the coelemic cavity lumen plus the membranes that line the lumen." [UBERON:cjm, Wikipedia:Body_cavity, Wikipedia:Coelom]
synonym: "coelem" RELATED []
synonym: "coelomic cavity" RELATED [EHDAA2:0004731]
synonym: "enterocoelom" NARROW [NCBITaxon:33511]
synonym: "haemocoelom" NARROW []
synonym: "schizocoelom" NARROW []
xref: EHDAA2:0004731
xref: Wikipedia:Coelom
is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
relationship: part_of NCBITaxon:6072 ! Eumetazoa
property_value: editor_note "EHDAA2 distingsuishes between the lumen, the lining, and the 'coelomic cavity', which despire it's name, is not a space - it is the aggregate of space plus lining." xsd:string
property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"}
property_value: UBPROP:0000007 "coelomic" xsd:string

[Term]
id: UBERON:0012054
name: myocoele
namespace: uberon
def: "The cavity within a myotome." [http://medical-dictionary.thefreedictionary.com/myocoele]
xref: EMAPA:31134
xref: VHOG:0001283
is_a: UBERON:0002553 ! anatomical cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0003082 ! myotome
relationship: luminal_space_of UBERON:0003082 ! myotome
relationship: part_of UBERON:0003082 ! myotome
property_value: UBPROP:0000003 "The central cavity within the mesoderm is the paired primary or embryonic coelom. Parts of the embryonic coelom often become enclosed in the mesoderm, forming a myocoel within the epimere, a nephrocoel within the mesomere, and simple coelom (body cavity) within the lateral plate mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001283", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.166 and Figure 5.6", source="http://bgee.unil.ch/"}

[Term]
id: UBERON:0012071
name: palate bone
namespace: uberon
def: "Any bone that is part of a palate." [https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "palatal bone" EXACT []
xref: EMAPA:37930 {source="MA:th"}
xref: NCIT:C33248
xref: UMLS:C1518857 {source="ncithesaurus:Palate_Bone"}
is_a: UBERON:0003457 ! head bone
is_a: UBERON:0008907 ! dermal bone
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0007375 ! roof of mouth
relationship: part_of UBERON:0012072 ! palatal part of dermatocranium
property_value: curator_notes "this is distinct (but not disjoint) from palatine bone" xsd:string

[Term]
id: UBERON:0012072
name: palatal part of dermatocranium
namespace: uberon
synonym: "dermatocranium, palatal series" RELATED [ISBN:0073040584]
synonym: "palatal series" RELATED [ISBN:0073040584]
is_a: UBERON:0000075 ! subdivision of skeletal system
relationship: part_of UBERON:0003113 ! dermatocranium
relationship: part_of UBERON:0007375 ! roof of mouth

[Term]
id: UBERON:0012075
name: replacement bone
namespace: uberon
def: "Bone that forms as a replacement of another structural tissue." [ZFA:0001628]
synonym: "replacement bones" EXACT OMO:0003004 [ZFA:0001628]
xref: AAO:0010768
xref: TAO:0001637
xref: ZFA:0001628
is_a: UBERON:0001474 {source="ZFA"} ! bone element
is_a: UBERON:0010522 {source="ZFA"} ! replacement element
property_value: UBPROP:0000001 "Bone that forms as a replacement of another structural tissue.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001637", ontology="TAO", source="TAO:wd"}
property_value: UBPROP:0000012 "This class was introduced to be consistent with the ZFA hierarchy. The corresponding TAO term was obsoleted, and never introduced into VSAO. Note that VSAO does have replacement element." xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0012168
name: umbilical cord blood
namespace: uberon
def: "Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]." [Wikipedia:Cord_blood]
comment: Cord blood is collected because it contains stem cells, which can be used to treat hematopoietic and genetic disorders.[WP]
subset: efo_slim
synonym: "cord blood" RELATED [BTO:0004053]
synonym: "fetal blood" RELATED [MESH:A12.207.152.200]
synonym: "umbilical cord blood" RELATED [MESH:A12.207.152.200]
xref: BTO:0004053
xref: CALOHA:TS-1079
xref: EFO:0001942
xref: MESH:D005312
xref: Wikipedia:Cord_blood
is_a: UBERON:0013755 ! arterial blood
intersection_of: UBERON:0000178 ! blood
intersection_of: located_in UBERON:0001310 ! umbilical artery
relationship: located_in UBERON:0001310 ! umbilical artery
relationship: part_of UBERON:0000323 ! late embryo

[Term]
id: UBERON:0012172
name: stomach primordium
namespace: uberon
def: "A primordium that has the potential to develop into a stomach." [OBOL:automatic]
subset: efo_slim
synonym: "stomach endoderm" RELATED [EFO:0002580]
xref: EFO:0002580
xref: NCIT:C34305
xref: UMLS:C1514976 {source="ncithesaurus:Stomach_Primordium"}
is_a: UBERON:0001048 ! primordium
intersection_of: UBERON:0001048 ! primordium
intersection_of: has_potential_to_develop_into UBERON:0000945 ! stomach
relationship: has_potential_to_develop_into UBERON:0000945 ! stomach
relationship: part_of UBERON:0003258 ! endoderm of foregut

[Term]
id: UBERON:0012180
name: head or neck skin
namespace: uberon
def: "A zone of skin that is part of a craniocervical region." [OBOL:automatic]
xref: EMAPA:37276 {source="MA:th"}
xref: MA:0000574
xref: NCIT:C12294
xref: UMLS:C1522650 {source="ncithesaurus:Skin_of_the_Scalp_and_Neck"}
is_a: UBERON:0000014 ! zone of skin
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0007811 ! craniocervical region
relationship: part_of UBERON:0007811 ! craniocervical region

[Term]
id: UBERON:0012193
name: phrenic vein
namespace: uberon
def: "The veins that run parallel to the phrenic arteries which include the two superior and two inferior phrenic veins." [ncithesaurus:Phrenic_Vein]
xref: EMAPA:37180 {source="MA:th"}
xref: MA:0002194
xref: NCIT:C53062
xref: UMLS:C1709532 {source="ncithesaurus:Phrenic_Vein"}
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0001103 ! diaphragm
relationship: drains UBERON:0001103 ! diaphragm
relationship: part_of RO:0002577 ! system

[Term]
id: UBERON:0012239
name: urinary bladder vasculature
namespace: uberon
def: "Network of tubes that carries blood through the distensible musculomembranous organ that serves to collect and store urine excreted by the kidneys[MP]." [MP:MP]
subset: human_reference_atlas
subset: pheno_slim
synonym: "bladder vasculature" EXACT []
synonym: "blood vessel of bladder" RELATED [EMAPA:28679]
synonym: "blood vessels of bladder" EXACT [EMAPA:28679]
synonym: "set of urinary bladder blood vessels" EXACT []
xref: EMAPA:28679
is_a: UBERON:0002201 ! vasculature of trunk
is_a: UBERON:0006876 ! vasculature of organ
intersection_of: UBERON:0002049 {source="EMAPA"} ! vasculature
intersection_of: part_of UBERON:0001255 {source="EMAPA"} ! urinary bladder
relationship: contributes_to_morphology_of UBERON:0001255 ! urinary bladder
relationship: part_of UBERON:0001255 ! urinary bladder
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0012240
name: urethral meatus
namespace: uberon
def: "External opening or orifice of the urethra through which urine and seminal fluid (in males only) leave the body; in males the meatus presents as a vertical slit normally positioned at the tip of glans penis; in females the meatus is located between the clitoris and the vagina in the vulvular vestibule of the female genitalia[MP]." [MP:MP, Wikipedia:Urinary_meatus]
subset: pheno_slim
synonym: "external meatus of urethra" EXACT [FMA:19650]
synonym: "external urethral orifice" EXACT [FMA:19650]
synonym: "external urethral ostium" EXACT [FMA:19650]
synonym: "external urinary meatus" EXACT [FMA:19650]
synonym: "meatus urinarius" EXACT OMO:0003011 []
synonym: "orificium urethrae externum" EXACT OMO:0003011 []
synonym: "orificium urethræ externum" EXACT OMO:0003011 []
synonym: "urethral meatus" EXACT [FMA:19650]
synonym: "urinary meatus" RELATED []
xref: EMAPA:37977 {source="MA:th"}
xref: FMA:19650
xref: SCTID:181424008
xref: Wikipedia:Urinary_meatus
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0010418 ! urethral opening
intersection_of: UBERON:0000161 ! orifice
intersection_of: connects UBERON:0010390 ! lumen of urethra
intersection_of: connects UBERON:0013514 ! space surrounding organism
intersection_of: part_of UBERON:0000057 ! urethra
relationship: connects UBERON:0010390 ! lumen of urethra
relationship: connects UBERON:0013514 ! space surrounding organism
relationship: part_of UBERON:0000057 ! urethra

[Term]
id: UBERON:0012241
name: male urethral meatus
namespace: uberon
def: "A urethral meatus that is part of a male urethra[Automatically generated definition]." [OBOL:automatic, Wikipedia:External_urethral_orifice_(male)]
synonym: "distal urethral opening of male" RELATED [EMAPA:36434]
synonym: "external orifice of male urethra" EXACT [FMA:85265]
synonym: "external urethral orifice (male)" EXACT [FMA:85265]
synonym: "male urethra ostium" EXACT [MA:0002642]
synonym: "ostium urethrae externum (urethra masculina)" EXACT OMO:0003011 [FMA:TA]
synonym: "urethral meatus of penile urethra" EXACT [EMAPA:36434]
synonym: "urethral opening of penile urethra" RELATED [EMAPA:36434]
xref: EMAPA:36434
xref: FMA:85265
xref: MA:0002642
xref: SCTID:279478000
xref: Wikipedia:External_urethral_orifice_(male)
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0012240 ! urethral meatus
intersection_of: UBERON:0012240 ! urethral meatus
intersection_of: part_of UBERON:0003101 ! male organism
relationship: part_of UBERON:0001299 ! glans penis
relationship: part_of UBERON:0001333 ! male urethra
property_value: UBPROP:0000001 "The external urethral orifice is the external opening or meatus of the urethra, normally placed at the tip of glans penis; it presents as a vertical slit, possibly bounded on either side by two small labia-like projections, In some cases the slit may be more rounded. This occurs naturally in some males and may also be a side effect of excess skin removal during circumcision. Congenital misplacement of the urethral orifice is called hypospadias when it is located in the underside (ventral aspect) of the penis, and epispadias when located in the dorsum (upper aspect). Improper shaping of the meatus can result in meatal stenosis." xsd:string {source="Wikipedia:External_urethral_orifice_(male)"}

[Term]
id: UBERON:0012242
name: internal urethral orifice
namespace: uberon
def: "The usually crescent-shaped opening of the urinary bladder into the urethra, placed at the anteroinferior angle (apex) of the urinary bladder trigone." [MGI:anna, MP:0011782]
subset: pheno_slim
synonym: "internal meatus of urethra" EXACT [FMA:85263]
synonym: "internal urethral orifice of urinary bladder" EXACT [FMA:85263]
synonym: "internal urethral ostium" EXACT [FMA:85263]
synonym: "internal urethral ostium" RELATED [MP:0011782]
synonym: "internal urinary meatus" RELATED [MP:0011782]
synonym: "orificium urethrae internum" EXACT OMO:0003011 [MP:0011782]
synonym: "ostium orificium internum" EXACT OMO:0003011 []
synonym: "ostium urethrae internum" EXACT OMO:0003011 [Wikipedia:Internal_urethral_orifice]
synonym: "vesicourethral orifice" EXACT [FMA:85263]
xref: FMA:85263
xref: SCTID:362228001
xref: Wikipedia:Internal_urethral_orifice
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0010418 ! urethral opening
intersection_of: UBERON:0000161 ! orifice
intersection_of: connects UBERON:0009958 ! bladder lumen
intersection_of: connects UBERON:0010390 ! lumen of urethra
intersection_of: part_of UBERON:0000057 ! urethra
relationship: connects UBERON:0009958 ! bladder lumen
relationship: connects UBERON:0010390 ! lumen of urethra
relationship: part_of UBERON:0000057 ! urethra

[Term]
id: UBERON:0012254
name: abdominal aorta artery
namespace: uberon
def: "An artery that originates from the abdominal aorta." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Abdominal_aorta#Branches]
subset: pheno_slim
synonym: "abdominal artery" EXACT []
synonym: "artery of abdomen" EXACT []
xref: SCTID:281470000
is_a: UBERON:0004573 ! systemic artery
intersection_of: UBERON:0001637 ! artery
intersection_of: branching_part_of UBERON:0001516 ! abdominal aorta
relationship: branching_part_of UBERON:0001516 ! abdominal aorta
relationship: part_of UBERON:0001516 ! abdominal aorta

[Term]
id: UBERON:0012274
name: columnar epithelium
namespace: uberon
def: "An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified]." [Wikipedia:Columnar_epithelium]
xref: Wikipedia:Columnar_epithelium
is_a: UBERON:0000483 ! epithelium
relationship: has_part CL:0000075 ! columnar/cuboidal epithelial cell

[Term]
id: UBERON:0012275
name: meso-epithelium
namespace: uberon
def: "Epithelium that derives from the mesoderm. [Automatically generated definition]." [OBOL:automatic]
synonym: "mesoderm-derived epithelium" EXACT []
synonym: "mesoepithelium" EXACT []
xref: FMA:86452
is_a: UBERON:0000483 ! epithelium
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000483 ! epithelium
intersection_of: develops_from UBERON:0000926 ! mesoderm

[Term]
id: UBERON:0012276
name: endometrium glandular epithelium
namespace: uberon
subset: human_reference_atlas
synonym: "glandular part of endometrium" EXACT [FMA:86488]
synonym: "uterine glands" EXACT []
synonym: "uterine glands set" EXACT []
xref: EMAPA:35308
xref: FMA:86488
xref: MA:0002732
is_a: UBERON:0004811 ! endometrium epithelium
is_a: UBERON:0006929 ! glandular columnar epithelium
is_a: UBERON:0007589 ! ciliated columnar oviduct epithelium
intersection_of: UBERON:0006799 ! glandular epithelium
intersection_of: part_of UBERON:0004811 ! endometrium epithelium
relationship: part_of UBERON:0004811 ! endometrium epithelium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0012292
name: embryonic cloacal fold
namespace: uberon
def: "One of the pair of mesenchymal swellings (folds) located on either side of the cloacal membrane during the indifferent stage of embryonic development; cranial to the cloacal membrane the folds unite to form the genital tubercle; caudally the folds are subdivided into urogenital folds anteriorly and anal folds posteriorly." [MP:0011836, MP:anna]
comment: We presume this is distinct from AAO:0001003, an external integumentary structure - check with amphibian anatomy ontology developers. AO notes: the text def states mesenchymal swelling, EHDAA2 splits into mesenchymal and epithelial parts
synonym: "cloacal fold" BROAD [EHDAA2:0004009]
xref: EHDAA2:0004009
is_a: UBERON:0000481 ! multi-tissue structure
relationship: adjacent_to UBERON:0006217 ! cloacal membrane
relationship: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0012469 {source="EHDAA2"} ! external anal region

[Term]
id: UBERON:0012299
name: mucosa of urethra
namespace: uberon
def: "A mucosa that is part of a urethra." [OBOL:automatic]
synonym: "mucous membrane of urethra" EXACT [FMA:76904]
synonym: "tunica mucosa urethrae" EXACT [FMA:TA]
synonym: "urethral mucosa" EXACT [FMA:76904]
xref: EMAPA:37912 {source="MA:th"}
xref: FMA:76904
xref: SCTID:362229009
is_a: UBERON:0000344 ! mucosa
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000057 ! urethra
relationship: part_of UBERON:0000057 ! urethra

[Term]
id: UBERON:0012314
name: embryonic facial prominence
namespace: uberon
def: "One of five swellings formed during the development of the face." [http://www.indiana.edu/~anat550/hnanim/face/face.html]
synonym: "embryonic facial process" RELATED []
synonym: "facial primordium" RELATED []
synonym: "primordium of face" RELATED []
xref: FMA:293103
xref: SCTID:89066004
is_a: UBERON:0002050 ! embryonic structure
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of UBERON:0000033 ! head

[Term]
id: UBERON:0012320
name: cervical artery
namespace: uberon
def: "An artery of the neck." [https://orcid.org/0000-0002-6601-2165]
xref: EMAPA:37075 {source="MA:th"}
xref: NCIT:C52850
xref: UMLS:C1707349 {source="ncithesaurus:Cervical_Artery"}
is_a: UBERON:0001637 ! artery
is_a: UBERON:0003502 ! neck blood vessel
intersection_of: UBERON:0001637 ! artery
intersection_of: part_of UBERON:0000974 ! neck

[Term]
id: UBERON:0012321
name: deep cervical artery
namespace: uberon
def: "The deep cervical artery (Profunda cervicalis) is an artery of the neck." [Wikipedia:Deep_cervical_artery]
subset: human_reference_atlas
synonym: "profunda cervicalis" RELATED [Wikipedia:Deep_cervical_artery]
xref: FMA:10659
xref: SCTID:244223002
xref: Wikipedia:Deep_cervical_artery
is_a: UBERON:0012320 ! cervical artery
intersection_of: UBERON:0012320 ! cervical artery
intersection_of: part_of UBERON:0035551 ! deep vasculature
relationship: connecting_branch_of UBERON:0004688 {source="FMA"} ! costo-cervical trunk
relationship: part_of UBERON:0035551 ! deep vasculature
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0012324
name: transverse cervical artery
namespace: uberon
def: "The transverse cervical artery (transverse artery of neck, transversa colli artery) is a branch of the thyrocervical trunk, running at a higher level than the suprascapular artery." [Wikipedia:Transverse_cervical_artery]
subset: human_reference_atlas
synonym: "cervical artery" RELATED [MA:0001936, Wikipedia:Transverse_cervical_artery]
synonym: "cervical transverse artery" RELATED [Wikipedia:Transverse_cervical_artery]
synonym: "descending branch of the transverse cervical" RELATED [Wikipedia:Transverse_cervical_artery]
synonym: "transversalis artery colli" RELATED [Wikipedia:Transverse_cervical_artery]
synonym: "transversalis colli artery" RELATED [Wikipedia:Transverse_cervical_artery]
synonym: "transverse cervical" RELATED [Wikipedia:Transverse_cervical_artery]
synonym: "transverse cervical vessels" RELATED [Wikipedia:Transverse_cervical_artery]
xref: FMA:10664
xref: MA:0001936
xref: SCTID:244224008
xref: Wikipedia:Transverse_cervical_artery
is_a: UBERON:0012320 ! cervical artery
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000012 "Unclear if MA class belongs here or in parent" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0012332
name: broad ligament of uterus
namespace: uberon
def: "A broad fold of peritoneum that extends from the side of the uterus to the wall of the pelvis." [MESH:A02.513.170, Wikipedia:Broad_ligament_of_the_uterus]
subset: human_reference_atlas
synonym: "broad ligament" RELATED [MESH:A02.513.170]
synonym: "broad uterine ligament" EXACT [FMA:16516]
synonym: "ligamentum latum uteri" RELATED OMO:0003011 []
xref: FMA:16516
xref: MESH:D001956
xref: NCIT:C12318
xref: SCTID:362723009
xref: UMLS:C0006205 {source="ncithesaurus:Broad_Ligament"}
xref: Wikipedia:Broad_ligament_of_the_uterus
is_a: UBERON:0000211 {source="MESH"} ! ligament
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: connects UBERON:0000459 ! uterine wall
relationship: connects UBERON:0002355 ! pelvic region of trunk
relationship: part_of UBERON:0002095 ! mesentery
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0012360
name: bone of jaw
namespace: uberon
def: "A bone element that is part of a jaw region." [OBOL:automatic]
synonym: "jaw bone" EXACT []
xref: EMAPA:35453
xref: MA:0003130
xref: SCTID:369003004
is_a: UBERON:0003462 ! facial bone
is_a: UBERON:0013765 ! digestive system element
intersection_of: UBERON:0001474 ! bone element
intersection_of: part_of UBERON:0011595 ! jaw region
relationship: part_of UBERON:0001708 ! jaw skeleton
property_value: editor_note "Do not manually classify under here - bones are automatically classified" xsd:string

[Term]
id: UBERON:0012361
name: internal anal region
namespace: uberon
xref: EHDAA2:0004588
is_a: UBERON:0000481 ! multi-tissue structure
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0001353 {source="EHDAA2"} ! anal region

[Term]
id: UBERON:0012367
name: muscle layer of intestine
namespace: uberon
def: "A muscle layer that is part of an intestine." [OBOL:automatic]
synonym: "intestinal muscularis propria" EXACT [FMA:15697]
synonym: "muscularis externa of intestine" EXACT [FMA:15697]
synonym: "smooth muscle of intestine" RELATED []
xref: FMA:15697
is_a: UBERON:0018261 ! muscular coat of digestive tract
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0001262 {source="FMA"} ! wall of intestine

[Term]
id: UBERON:0012375
name: subserosa
namespace: uberon
def: "A layer of tissue between the muscularis and serosa." [Wikipedia:Subserosa]
comment: Contains nerves, blood vessels, lymphatics and lymph nodes
subset: human_reference_atlas
xref: FMA:45636
xref: NCIT:C94494
xref: SCTID:2255006
xref: UMLS:C0225334 {source="ncithesaurus:Subserosa"}
xref: Wikipedia:Subserosa
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: adjacent_to UBERON:0000042 ! serous membrane
intersection_of: composed_primarily_of UBERON:0006815 ! areolar connective tissue
relationship: adjacent_to UBERON:0000042 ! serous membrane
relationship: composed_primarily_of UBERON:0006815 ! areolar connective tissue
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0012378
name: muscle layer of urinary bladder
namespace: uberon
def: "A muscular coat that is part of a urinary bladder." [OBOL:automatic]
subset: human_reference_atlas
synonym: "bladder muscular coat" EXACT []
synonym: "muscle layer of urinary bladder" EXACT [FMA:15930]
synonym: "muscular coat of bladder" EXACT [FMA:15930]
synonym: "muscular coat of urinary bladder" EXACT [FMA:15930]
synonym: "muscular layer of bladder" EXACT [FMA:15930]
synonym: "muscular layer of urinary bladder" EXACT [FMA:15930]
synonym: "tunica musculari vesicae" EXACT [FMA:TA]
synonym: "tunica muscularis (vesica urinaria)" EXACT [FMA:TA]
xref: FMA:15930
xref: NCIT:C32206
xref: UMLS:C1288327 {source="ncithesaurus:Bladder_Muscular_Coat"}
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0006660 ! muscular coat
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0001255 ! urinary bladder
relationship: has_part UBERON:0004228 ! urinary bladder smooth muscle
relationship: part_of UBERON:0001256 {source="FMA"} ! wall of urinary bladder
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0012416
name: respiratory system arterial smooth muscle
namespace: uberon
subset: human_reference_atlas
xref: EMAPA:37567 {source="MA:th"}
xref: MA:0001802
is_a: UBERON:0004297 ! respiratory system blood vessel smooth muscle
is_a: UBERON:0004695 ! arterial system smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0003643 ! respiratory system arterial blood vessel
relationship: part_of UBERON:0003643 ! respiratory system arterial blood vessel
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0012418
name: respiratory system venous smooth muscle
namespace: uberon
def: "A smooth muscle tissue that is part of a respiratory system venous blood vessel." [OBOL:automatic]
subset: human_reference_atlas
xref: EMAPA:37586 {source="MA:th"}
xref: MA:0001812
is_a: UBERON:0004696 ! venous system smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0003476 ! respiratory system venous blood vessel
relationship: part_of UBERON:0003476 ! respiratory system venous blood vessel
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0012423
name: layer of microvilli
namespace: uberon
def: "A layer of microvilli, Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments[GO,modified]." [GO:0005902, Wikipedia:Microvillus]
synonym: "microvilli" RELATED [MESH:A11.284.180.565]
synonym: "microvillus" RELATED [FMA:67296]
xref: FMA:67296
xref: MESH:D008871
xref: NCIT:C33112
xref: UMLS:C0026049 {source="ncithesaurus:Microvillus"}
xref: Wikipedia:Microvillus
is_a: UBERON:0005162 ! multi cell part structure
relationship: composed_primarily_of GO:0005902 ! microvillus
property_value: UBPROP:0000009 "a wide variety of physiological and cellular functions including absorption, secretion, cellular adhesion, and mechanotransduction" xsd:string
property_value: UBPROP:0000009 "increases the surface area of a cell lining whilst minimizing increase in volume" xsd:string
property_value: UBPROP:0000012 "FMA class represents an individual microvillus." xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0012425
name: striated border microvillus layer
namespace: uberon
def: "A microvillus layer that is striated and found in the intestine." [http://medical-dictionary.thefreedictionary.com/striated+border, http://orcid.org/0000-0002-6601-2165]
synonym: "striated border" RELATED [FMA:70978]
xref: FMA:70978
xref: NCIT:C33634
is_a: UBERON:0012423 ! layer of microvilli
relationship: part_of UBERON:0000160 ! intestine
property_value: UBPROP:0000012 "FMA class represents an individual microvillus" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0012429
name: hematopoietic tissue
namespace: uberon
def: "Blood-forming tissue, consisting of reticular fibers and cells." [http://encyclopedia2.thefreedictionary.com/hematopoietic+tissue]
synonym: "bone marrow tissue" NARROW [NCBITaxon:9606]
synonym: "haemopoietic tissue" EXACT [FMA:14073]
synonym: "hematopoietic tissue" EXACT [FMA:14073]
synonym: "hemopoietic tissue" EXACT [FMA:14073]
synonym: "textus haemopoieticus" EXACT [FMA:14073]
xref: CALOHA:TS-2142
xref: FMA:14073
xref: NCIT:C13051
xref: UMLS:C0229619 {source="ncithesaurus:Hematopoietic_Tissue"}
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0034769 {source="FMA"} ! lymphomyeloid tissue
intersection_of: UBERON:0000479 ! tissue
intersection_of: site_of GO:0030097 ! hemopoiesis
relationship: part_of UBERON:0002371 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! bone marrow
relationship: part_of UBERON:0002390 {source="defitional"} ! hematopoietic system
relationship: site_of GO:0030097 ! hemopoiesis
property_value: UBPROP:0000008 "Bone marrow in humans, kidney interstitium in Danio, within a stroma of reticuloendothelial tissue" xsd:string

[Term]
id: UBERON:0012430
name: tunica fibrosa of eyeball
namespace: uberon
def: "The sclera and cornea form the fibrous tunic of the bulb of the eye; the sclera is opaque, and constitutes the posterior five-sixths of the tunic; the cornea is transparent, and forms the anterior sixth." [Wikipedia:Fibrous_tunic_of_eyeball]
synonym: "corneosclera" RELATED [Wikipedia:Fibrous_tunic_of_eyeball]
synonym: "fibrous layer of eyeball" EXACT [FMA:58102]
synonym: "fibrous tunic" RELATED [Wikipedia:Fibrous_tunic_of_eyeball]
synonym: "tunica fibrosa" BROAD []
xref: FMA:58102
xref: SCTID:361318005
xref: Wikipedia:Fibrous_tunic_of_eyeball
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0004923 {source="FMA"} ! organ component layer
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
relationship: has_part UBERON:0000964 ! cornea
relationship: has_part UBERON:0001773 ! sclera
relationship: part_of UBERON:0010230 ! eyeball of camera-type eye
property_value: RO:0002175 NCBITaxon:7955 {source="DOI:10.1177/0192623311409597"}

[Term]
id: UBERON:0012463
name: cloacal lumen
namespace: uberon
def: "An anatomical space that is enclosed by a cloaca." [OBOL:automatic]
synonym: "cloaca lumen" EXACT [ZFA:0000330]
synonym: "cloacal chamber" EXACT [ZFA:0000330]
xref: TAO:0000330
xref: ZFA:0000330
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000162 ! cloaca
relationship: luminal_space_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0012465 {source="cjm"} ! lumen of terminal part of digestive tract
property_value: UBPROP:0000012 "the ZFA class belongs here as it is an anatomical space. See https://sourceforge.net/p/obo/zebrafish-anatomy-zfa-term-requests/102/" xsd:string {external_ontology="ZFA"}

[Term]
id: UBERON:0012464
name: cloacal vent
namespace: uberon
def: "The opening of the cloacal chamber to the outside of the organism. Birds maintain a single cloacal opening throughout their lives." [http://orcid.org/0000-0002-6601-2165]
synonym: "cloacal opening" EXACT []
synonym: "cloacal orifice" RELATED []
synonym: "vent" RELATED []
is_a: UBERON:0000161 ! orifice
intersection_of: UBERON:0000161 ! orifice
intersection_of: part_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0000162 ! cloaca

[Term]
id: UBERON:0012465
name: lumen of terminal part of digestive tract
namespace: uberon
def: "An anatomical space that is enclosed by a terminal part of digestive tract." [OBOL:automatic]
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0006866 ! terminal part of digestive tract
relationship: luminal_space_of UBERON:0006866 ! terminal part of digestive tract
relationship: part_of UBERON:0006866 ! terminal part of digestive tract
property_value: UBPROP:0000008 "includes the cloacal lumen, in species where this is present" xsd:string

[Term]
id: UBERON:0012466
name: extraembryonic cavity
namespace: uberon
synonym: "extraembryonic cavities" RELATED OMO:0003004 [EHDAA2:0000472]
xref: EHDAA2:0000472
xref: EMAPA:16054
xref: VHOG:0000767
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: part_of UBERON:0016887 ! entire extraembryonic component
relationship: part_of UBERON:0016887 ! entire extraembryonic component

[Term]
id: UBERON:0012467
name: enclosed anatomical space
namespace: uberon
def: "An anatomical space with no opening to another space or to the exterior." [AEO:0000222]
synonym: "closed anatomical space" EXACT []
xref: AEO:0000222
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: has_quality PATO:0000608 ! closed
relationship: has_quality PATO:0000608 ! closed

[Term]
id: UBERON:0012469
name: external anal region
namespace: uberon
xref: EHDAA2:0004589
is_a: UBERON:0000481 ! multi-tissue structure
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0001353 {source="EHDAA2"} ! anal region

[Term]
id: UBERON:0012475
name: skeleton of pectoral complex
namespace: uberon
def: "The collection of all skeletal elements in a pectoral complex - i.e. the combination of free limb or fin plus pectoral girdle." [https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "bones of upper limb" RELATED [FMA:24139]
synonym: "ossa membri superioris" RELATED [FMA:TA]
synonym: "pectoral complex skeleton" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "set of bones of upper limb" RELATED [FMA:24139]
synonym: "skeleton of anterior limb/fin and girdle" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "upper limb skeleton" RELATED [FMA:24139]
xref: FMA:24139
is_a: UBERON:0010912 ! subdivision of skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: skeleton_of UBERON:0010708 ! pectoral complex
relationship: part_of UBERON:0002091 ! appendicular skeleton
relationship: part_of UBERON:0010708 {source="FMA"} ! pectoral complex
relationship: skeleton_of UBERON:0010708 ! pectoral complex

[Term]
id: UBERON:0012476
name: skeleton of pelvic complex
namespace: uberon
def: "The collection of all skeletal elements in a pelvic complex - i.e. the combination of free limb or fin plus pelvic girdle." [https://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "bones of lower limb" RELATED [FMA:24140]
synonym: "lower limb skeleton" RELATED [FMA:24140]
synonym: "ossa membri inferioris" RELATED [FMA:TA]
synonym: "pelvic complex skeleton" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "set of bones of lower limb" RELATED [FMA:24140]
synonym: "skeleton of posterior limb/fin and girdle" RELATED [https://orcid.org/0000-0002-6601-2165]
xref: FMA:24140
is_a: UBERON:0010912 ! subdivision of skeleton
intersection_of: UBERON:0010912 ! subdivision of skeleton
intersection_of: skeleton_of UBERON:0010709 ! pelvic complex
relationship: part_of UBERON:0002091 ! appendicular skeleton
relationship: part_of UBERON:0010709 {source="FMA"} ! pelvic complex
relationship: skeleton_of UBERON:0010709 ! pelvic complex

[Term]
id: UBERON:0012477
name: dorsal part of neck
namespace: uberon
def: "The posterior region of the neck, including the suboccipital region." [MP:0012723]
subset: pheno_slim
synonym: "back of neck" EXACT [FMA:24189]
synonym: "hindneck" RELATED []
synonym: "nape" BROAD [BTO:0000957]
synonym: "nape of neck" EXACT []
synonym: "neck back" EXACT [FMA:24189]
synonym: "nucha" EXACT [FMA:24189]
synonym: "nuchal region" EXACT [FMA:24189]
synonym: "posterior cervical region" EXACT [FMA:24189]
synonym: "posterior neck region" EXACT [FMA:24189]
synonym: "posterior part of neck" EXACT [FMA:24189]
synonym: "regio cervicalis posterior" EXACT [FMA:TA]
xref: BTO:0000957
xref: FMA:24189
xref: SCTID:182326009
xref: SCTID:304036007
is_a: UBERON:0005434 {source="FMA"} ! cervical region
relationship: in_dorsal_side_of UBERON:0000974 {source="FMA"} ! neck
relationship: part_of UBERON:0001137 {source="FMA"} ! dorsum
property_value: UBPROP:0000007 "nuchal" xsd:string

[Term]
id: UBERON:0012478
name: cloacal gland
namespace: uberon
def: "A gland that is part of a cloaca." [OBOL:automatic]
is_a: UBERON:0003408 ! gland of digestive tract
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0000162 ! cloaca

[Term]
id: UBERON:0012480
name: cloacal mucosa
namespace: uberon
alt_id: UBERON:0003349
def: "A mucosa that is part of a cloaca [Automatically generated definition]." [OBOL:automatic]
synonym: "cloaca mucosa" EXACT []
synonym: "cloaca mucosa of organ" EXACT []
synonym: "cloaca mucous membrane" EXACT []
synonym: "cloaca organ mucosa" EXACT []
synonym: "cloacal mucous membrane" EXACT []
synonym: "mucosa of cloaca" EXACT []
synonym: "mucosa of organ of cloaca" EXACT []
synonym: "mucous membrane of cloaca" EXACT []
synonym: "organ mucosa of cloaca" EXACT []
is_a: UBERON:0000344 ! mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0000162 ! cloaca

[Term]
id: UBERON:0012481
name: cloacal epithelium
namespace: uberon
def: "An epithelium that is part of a cloaca." [http://orcid.org/0000-0002-6601-2165]
synonym: "cloacal endoderm" RELATED [EMAPA:27577]
xref: EMAPA:27577
xref: EMAPA:36070
xref: ZFA:0005783
is_a: UBERON:0003929 ! digestive tract epithelium
is_a: UBERON:0005911 ! endo-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0000162 ! cloaca
property_value: UBPROP:0000001 "cloacal epithelium (cle) (syn: cloacal endoderm) (TS17-TS20): the cloacal epithelium is derived from endoderm and lines the cloacal cavity. It is marked by Shh and Cdh1 and lines the cloacal lumen. The cloacal epithelium gives rise to the urogenital sinus epithelium, hindgut epithelium and the urethral plate epithelium." xsd:string {source="EMAPA:27577"}

[Term]
id: UBERON:0012482
name: submucosa of cloaca
namespace: uberon
def: "A submucosa that is part of a cloaca [Automatically generated definition]." [OBOL:automatic]
synonym: "cloaca submucosa" EXACT []
synonym: "cloacal submucosa" EXACT []
is_a: UBERON:0018257 ! submucosa of digestive tract
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0000162 ! cloaca

[Term]
id: UBERON:0012483
name: serosa of cloaca
namespace: uberon
def: "A serous membrane that is part of a cloaca [Automatically generated definition]." [OBOL:automatic]
synonym: "cloaca serosa" EXACT []
synonym: "cloaca serous membrane" EXACT []
synonym: "cloacal serosa" EXACT []
synonym: "serous membrane of cloaca" EXACT []
synonym: "visceral peritoneum of cloaca" EXACT []
is_a: UBERON:0000042 ! serous membrane
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0000162 ! cloaca

[Term]
id: UBERON:0012485
name: cloacal villus
namespace: uberon
synonym: "cloacal villi" EXACT OMO:0003004 []
is_a: UBERON:0012423 ! layer of microvilli
intersection_of: UBERON:0012423 ! layer of microvilli
intersection_of: part_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0000162 ! cloaca

[Term]
id: UBERON:0012486
name: muscle layer of cloaca
namespace: uberon
def: "A muscular coat that is part of a cloaca." [OBOL:automatic]
synonym: "muscularis externa of cloaca" EXACT []
synonym: "smooth muscle of cloaca" RELATED []
is_a: UBERON:0018261 ! muscular coat of digestive tract
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0000162 ! cloaca

[Term]
id: UBERON:0012488
name: muscle layer of duodenum
namespace: uberon
def: "A muscular coat that is part of a duodenum." [OBOL:automatic]
synonym: "duodenal muscularis propria" EXACT [FMA:14944]
synonym: "muscularis externa of duodenum" EXACT [FMA:14944]
synonym: "muscularis propria of duodenum" RELATED [https://orcid.org/0000-0002-6601-2165]
synonym: "smooth muscle of duodenum" RELATED [https://orcid.org/0000-0002-6601-2165]
xref: FMA:14944
xref: SCTID:362147007
is_a: UBERON:0011201 ! muscle layer of small intestine
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: part_of UBERON:0002114 ! duodenum

[Term]
id: UBERON:0012489
name: muscle layer of colon
namespace: uberon
def: "A muscular coat that is part of a colon." [OBOL:automatic]
subset: human_reference_atlas
synonym: "colon muscularis" RELATED [MA:0003198]
synonym: "colonic muscularis propria" EXACT [FMA:14986]
synonym: "muscular coat of colon" EXACT [FMA:14986]
synonym: "muscular layer of colon" EXACT [FMA:14986]
synonym: "muscularis externa of colon" EXACT [FMA:14986]
synonym: "tunica muscularis coli" EXACT [FMA:TA]
xref: EMAPA:27383
xref: FMA:14986
xref: MA:0003198
xref: SCTID:362158003
is_a: UBERON:0011198 ! muscle layer of large intestine
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0012490
name: muscle layer of anal canal
namespace: uberon
def: "A muscular coat that is part of a anal canal." [OBOL:automatic]
synonym: "anal canal muscularis propria" EXACT []
synonym: "anal muscularis propria" EXACT [FMA:15708]
synonym: "muscular coat of anal canal" EXACT []
synonym: "muscular layer of anal canal" EXACT []
synonym: "muscularis externa of anal canal" EXACT []
synonym: "muscularis propria of anal canal" EXACT [FMA:15708]
xref: FMA:15708
xref: SCTID:362171000
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0011198 ! muscle layer of large intestine
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0000159 ! anal canal
relationship: part_of UBERON:0000159 ! anal canal

[Term]
id: UBERON:0012499
name: serosa of uterine tube
namespace: uberon
def: "A serous membrane that is part of a fallopian tube." [OBOL:automatic]
synonym: "serosa of fallopian tube" EXACT [FMA:18316]
synonym: "serosa of oviduct" EXACT [FMA:18316]
synonym: "serous coat of uterine tube" EXACT [FMA:18316]
synonym: "tunica serosa (tuba uterina)" EXACT [FMA:18316]
synonym: "tunica serosa tubae uterinae" EXACT [FMA:TA]
synonym: "uterine tubal serosa" EXACT [FMA:18316]
synonym: "uterine tube serosa" EXACT [FMA:18316]
xref: FMA:18316
xref: SCTID:259593000
is_a: UBERON:0000042 ! serous membrane
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0003889 ! fallopian tube
relationship: part_of UBERON:0003889 ! fallopian tube

[Term]
id: UBERON:0012504
name: adventitia of esophagus
namespace: uberon
def: "An adventitia that is part of a esophagus." [OBOL:automatic]
synonym: "adventitia of oesophagus" EXACT [FMA:63006]
synonym: "adventitious layer of esophagus" EXACT [FMA:63006]
synonym: "esophageal adventitia" EXACT [FMA:63006]
synonym: "esophagus adventitia" EXACT [FMA:63006]
synonym: "tunica adventitia (esophagus)" EXACT [FMA:63006]
synonym: "tunica adventitia oesophageae" EXACT [FMA:TA]
xref: FMA:63006
xref: SCTID:85950006
is_a: UBERON:0005742 ! adventitia
intersection_of: UBERON:0005742 ! adventitia
intersection_of: part_of UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001043 ! esophagus

[Term]
id: UBERON:0012615
name: umbilical smooth muscle
namespace: uberon
def: "A smooth muscle tissue that is part of a umbilical cord." [OBOL:automatic]
xref: BTO:0001847
is_a: UBERON:0001135 ! smooth muscle tissue
is_a: UBERON:0005292 ! extraembryonic tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0002331 ! umbilical cord
relationship: part_of UBERON:0002331 ! umbilical cord

[Term]
id: UBERON:0012650
name: gastroduodenal junction
namespace: uberon
def: "An anatomical junction that connects a stomach and connects a duodenum." [OBOL:automatic]
xref: FMA:17046
xref: SCTID:264014000
is_a: UBERON:1100000 ! digestive tract junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0000945 ! stomach
intersection_of: connects UBERON:0002114 ! duodenum
relationship: connects UBERON:0000945 ! stomach
relationship: connects UBERON:0002114 ! duodenum
relationship: part_of UBERON:0000945 ! stomach

[Term]
id: UBERON:0012651
name: mucosa of gastroduodenal junction
namespace: uberon
def: "A mucosa that is part of a gastroduodenal junction." [OBOL:automatic]
synonym: "gastroduodenal mucosa" EXACT [BTO:0005415]
xref: BTO:0005415
is_a: UBERON:0001199 ! mucosa of stomach
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0012650 ! gastroduodenal junction
relationship: part_of UBERON:0001199 ! mucosa of stomach
relationship: part_of UBERON:0012650 ! gastroduodenal junction

[Term]
id: UBERON:0013126
name: vein of abdomen
namespace: uberon
def: "A vein that is part of a abdomen." [OBOL:automatic]
subset: grouping_class
synonym: "abdominal vein" EXACT []
xref: SCTID:281473003
is_a: UBERON:0001638 ! vein
is_a: UBERON:0003497 ! abdomen blood vessel
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0000916 ! abdomen
property_value: curator_notes "this class groups all veins that are in the abdomen. The term 'abdominal vein' may have specific meanings in different contexts. The lateral abdominal veins are present in fishes but usually merged or absent in tetrapods; in amphibians, the L&R abdominal veins merge into the ventral abdominal vein" xsd:string
property_value: editor_note "TODO mirror representation of abdominal aorta" xsd:string

[Term]
id: UBERON:0013127
name: pulmonary venous system
namespace: uberon
def: "The part of the venous system that drains the lungs[Kardong]." [ISBN:0073040584, Wikipedia:Pulmonary_venous_system]
synonym: "pulmonary venous circulatory system" EXACT []
xref: Wikipedia:Pulmonary_venous_system
is_a: UBERON:0002049 ! vasculature
relationship: channels_from UBERON:0000102 ! lung vasculature
relationship: part_of UBERON:0004582 ! venous system
property_value: UBPROP:0000001 "Pulmonary circulation is the half portion of the cardiovascular system which carries oxygen-depleted blood away from the heart, to the lungs, and returns oxygenated (oxygen-rich) blood back to the heart. The term pulmonary circulation is readily paired and contrasted with the systemic circulation. A separate system known as the bronchial circulation supplies blood to the tissue of the larger airways of the lung." xsd:string {source="Wikipedia:Pulmonary_circulation"}

[Term]
id: UBERON:0013136
name: vein of lip
namespace: uberon
def: "A vein that drains a lip." [OBOL:automatic]
synonym: "labial vein" RELATED []
synonym: "labial vein of face" EXACT []
synonym: "lip vein" EXACT [OBOL:automatic]
synonym: "vena labialis" EXACT OMO:0003011 []
xref: SCTID:367664002
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0001833 ! lip
relationship: drains UBERON:0001833 ! lip
relationship: part_of RO:0002577 ! system
relationship: tributary_of UBERON:0001653 {source="FMA"} ! facial vein

[Term]
id: UBERON:0013140
name: systemic vein
namespace: uberon
def: "Any vein within the general circulation that transports blood back to the right atrium of the heart." [ncithesaurus:Systemic_Vein]
synonym: "systemic venous tree organ part" EXACT [FMA:66644]
xref: FMA:66644
xref: NCIT:C33719
xref: SCTID:244389004
xref: UMLS:C0447117 {source="ncithesaurus:Systemic_Vein"}
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0004581 ! systemic venous system
relationship: part_of UBERON:0004581 ! systemic venous system

[Term]
id: UBERON:0013158
name: foregut-midgut junction gland
namespace: uberon
def: "A gland that is part of a foregut-midgut junction." [OBOL:automatic]
synonym: "gland of foregut-midgut junction" EXACT [EMAPA:17065]
xref: EHDAA2:0000574
xref: EMAPA:17065
is_a: UBERON:0003408 ! gland of digestive tract
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0006235 ! foregut-midgut junction
relationship: part_of UBERON:0006235 ! foregut-midgut junction

[Term]
id: UBERON:0013191
name: ovarian cortex
namespace: uberon
def: "The layer of the ovarian stroma lying immediately beneath the tunica albuginea, composed of connective tissue cells and fibers, among which are scattered primary and secondary (antral) follicles in various stages of development; the cortex varies in thickness according to the age of the individual, becoming thinner with advancing years; included in the follicles are the cumulus oophorus, membrana granulosa (and the granulosa cells inside it), corona radiata, zona pellucida, and primary oocyte; the zona pellucida, theca of follicle, antrum and liquor folliculi are also contained in the follicle; also in the cortex is the corpus luteum derived from the follicles." [MGI:anna]
subset: human_reference_atlas
subset: pheno_slim
synonym: "cortex of ovary" EXACT [FMA:18613]
synonym: "cortex ovarii (zona parenchymatosa)" EXACT [FMA:18613]
xref: EMAPA:37927 {source="MA:th"}
xref: FMA:18613
xref: NCIT:C33243
xref: UMLS:C0227878 {source="ncithesaurus:Ovarian_Cortex"}
is_a: UBERON:0001851 ! cortex
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001851 ! cortex
intersection_of: part_of UBERON:0000992 ! ovary
relationship: part_of UBERON:0006960 ! ovary stroma
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0013212
name: anal sac gland secretion
namespace: uberon
def: "A bodily secretion that is produced by a gland of anal sac." [OBOL:automatic]
synonym: "anal gland secretion" RELATED []
synonym: "castoreum" NARROW SENSU [NCBITaxon:29132]
synonym: "civet" NARROW SENSU [NCBITaxon:9673]
synonym: "hyena butter" RELATED SENSU [Wikipedia:Hyena_butter]
synonym: "musk" RELATED [NCBITaxon:30533]
synonym: "odorous sac" RELATED []
is_a: UBERON:0000456 ! secretion of exocrine gland
intersection_of: UBERON:0000456 ! secretion of exocrine gland
intersection_of: produced_by UBERON:0004760 ! gland of anal canal
relationship: produced_by UBERON:0004760 ! gland of anal canal
property_value: RO:0002175 NCBITaxon:119825
property_value: RO:0002175 NCBITaxon:30533
property_value: RO:0002175 NCBITaxon:9673
property_value: UBPROP:0000008 "the anal gland secretions of species such as civet and beavers are used perfumery" xsd:string

[Term]
id: UBERON:0013232
name: serous acinus
namespace: uberon
def: "The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm]
synonym: "acinus of serous gland" EXACT []
xref: FMA:86279
is_a: UBERON:0011858 ! acinus of exocrine gland
intersection_of: UBERON:0009842 ! glandular acinus
intersection_of: part_of UBERON:0000409 ! serous gland
relationship: composed_primarily_of CL:0000313 ! serous secreting cell
relationship: part_of UBERON:0000409 ! serous gland

[Term]
id: UBERON:0013238
name: future glans
namespace: uberon
is_a: UBERON:0005423 ! developing anatomical structure
union_of: UBERON:0013239 ! future glans penis
union_of: UBERON:0013240 ! future glans clitoris
relationship: has_potential_to_develop_into UBERON:0035651 ! glans
relationship: part_of UBERON:0011757 ! differentiated genital tubercle

[Term]
id: UBERON:0013239
name: future glans penis
namespace: uberon
def: "A future glans that is part of a male genital tubercle." [OBOL:automatic]
synonym: "glans of male genital tubercle" EXACT []
xref: EMAPA:29252
is_a: UBERON:0013238 ! future glans
intersection_of: UBERON:0013238 ! future glans
intersection_of: part_of UBERON:0006261 ! male genital tubercle
relationship: part_of UBERON:0006261 {source="EMAPA"} ! male genital tubercle

[Term]
id: UBERON:0013240
name: future glans clitoris
namespace: uberon
def: "A future glans that is part of a female genital tubercle." [OBOL:automatic]
synonym: "glans of female genital tubercle" EXACT []
xref: EMAPA:19170
is_a: UBERON:0013238 ! future glans
intersection_of: UBERON:0013238 ! future glans
intersection_of: part_of UBERON:0006233 ! female genital tubercle
relationship: part_of UBERON:0006233 {source="EMAPA"} ! female genital tubercle

[Term]
id: UBERON:0013241
name: embryonic urethral groove
namespace: uberon
def: "The precursor of the urethra." [http://orcid.org/0000-0002-6601-2165]
synonym: "sulcus urethralis primarius" EXACT OMO:0003011 [Wikipedia:Urethral_groove]
synonym: "urethral groove" EXACT []
synonym: "urethral sulcus" EXACT []
xref: SCTID:361531004
xref: Wikipedia:Urethral_groove
is_a: UBERON:0002050 ! embryonic structure
relationship: develops_from UBERON:0004876 {source="Wikipedia"} ! urogenital fold
property_value: UBPROP:0000008 "In humans, the urethral groove is a temporary linear indentation on the underside (ventral side) of the male penis during embryonic development. It typically appears around 8 weeks of gestation and becomes closed into a normal male urethra by the 12th week" xsd:string {source="Wikipedia:Urethral_groove"}

[Term]
id: UBERON:0013247
name: male paramesonephric duct
namespace: uberon
def: "An epithelial tube that develops from a Mullerian duct in a male. Later degenerates." [http://orcid.org/0000-0002-6601-2165]
synonym: "degenerating mesonephric portion of male paramesonephric duct" RELATED [EMAPA:29161]
xref: EHDAA2:0001052
xref: EMAPA:29161
xref: EMAPA:35661
is_a: UBERON:0003914 ! epithelial tube
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0012275 ! meso-epithelium
intersection_of: UBERON:0003914 ! epithelial tube
intersection_of: develops_from UBERON:0003890 ! Mullerian duct
intersection_of: part_of UBERON:0000079 ! male reproductive system
relationship: develops_from UBERON:0003890 {source="EHDAA2"} ! Mullerian duct
relationship: part_of UBERON:0000079 {source="EHDAA2"} ! male reproductive system
property_value: editor_note "consider separating the duct from the degenerating portion, as in EMAPA" xsd:string

[Term]
id: UBERON:0013411
name: cranial cavity
namespace: uberon
def: "Anatomical cavity that is the lumen of the skull and contains the brain." [UBERON:cjm]
synonym: "cavitas cranii" EXACT OMO:0003011 [FMA:9644, FMA:TA]
synonym: "intracranial cavity" RELATED [Wikipedia:Cranial_cavity]
synonym: "intracranial space" RELATED [Wikipedia:Cranial_cavity]
xref: EMAPA:37497 {source="MA:th"}
xref: FMA:9644
xref: MA:0003061
xref: NCIT:C77638
xref: neuronames:2806
xref: SCTID:264452006
xref: UMLS:C0230041 {source="ncithesaurus:Cranial_Cavity"}
xref: Wikipedia:Cranial_cavity
is_a: UBERON:0002553 ! anatomical cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0003129 ! skull
relationship: luminal_space_of UBERON:0003129 ! skull
relationship: part_of UBERON:0003129 {source="Wikipedia"} ! skull
property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI

[Term]
id: UBERON:0013479
name: lung endothelium
namespace: uberon
def: "A blood vessel endothelium that is part of a lung [Automatically generated definition]." [OBOL:automatic]
synonym: "respiratory endothelium" RELATED [BTO:0004128]
xref: BTO:0004128
xref: CALOHA:TS-0573
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0000115 ! lung epithelium
is_a: UBERON:0004702 ! respiratory system blood vessel endothelium
intersection_of: UBERON:0004638 ! blood vessel endothelium
intersection_of: part_of UBERON:0002048 ! lung

[Term]
id: UBERON:0013501
name: cloacal sphincter
namespace: uberon
def: "A sphincter muscle that is part of a cloaca." [OBOL:automatic]
comment: the muscles of the cloacal sphincter specialise into the perineal muscles in mammals (Gegenbaur, 1883; Popowsky, 1899; Nishi, 1938).
synonym: "sphincter cloacae" EXACT OMO:0003004 []
xref: NCIT:C34129
xref: UMLS:C1516658 {source="ncithesaurus:Cloacal_Sphincter"}
is_a: UBERON:0004590 ! sphincter muscle
is_a: UBERON:0014783 ! cloacal muscle
intersection_of: UBERON:0004590 ! sphincter muscle
intersection_of: part_of UBERON:0000162 ! cloaca

[Term]
id: UBERON:0013503
name: caudal vertebra cartilage element
namespace: uberon
alt_id: UBERON:0013517
def: "A caudal vertebra endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic]
synonym: "coccygeal vertebra cartilage element" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "coccygeal vertebral cartilage condensation group" EXACT [EHDAA2:0000260]
synonym: "tail vertebral cartilage condensation" EXACT [EMAPA:18044]
xref: EHDAA2:0000260
xref: EMAPA:18044
is_a: UBERON:0011094 ! vertebra cartilage element
is_a: UBERON:0018142 ! caudal vertebra endochondral element
is_a: UBERON:2001457 ! postcranial axial cartilage
intersection_of: UBERON:0018142 ! caudal vertebra endochondral element
intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue
relationship: develops_from UBERON:0013504 ! caudal vertebra pre-cartilage condensation
relationship: has_potential_to_develop_into UBERON:0001095 ! caudal vertebra

[Term]
id: UBERON:0013504
name: caudal vertebra pre-cartilage condensation
namespace: uberon
alt_id: UBERON:0013518
def: "A caudal vertebra endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic]
synonym: "coccygeal vertebra pre-cartilage condensation" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "tail vertebral pre-cartilage condensation" EXACT [EMAPA:18045]
xref: EMAPA:18045
is_a: UBERON:0011095 ! vertebra pre-cartilage condensation
is_a: UBERON:0018142 ! caudal vertebra endochondral element
intersection_of: UBERON:0018142 ! caudal vertebra endochondral element
intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation

[Term]
id: UBERON:0013505
name: cervical vertebra cartilage element
namespace: uberon
def: "A cervical vertebra endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic]
synonym: "cervical vertebral cartilage condensation group" EXACT [EHDAA2:0000240]
xref: EHDAA2:0000240
is_a: UBERON:0003601 ! neck cartilage
is_a: UBERON:0011094 ! vertebra cartilage element
is_a: UBERON:0015007 ! cervical vertebra endochondral element
is_a: UBERON:2001457 ! postcranial axial cartilage
intersection_of: UBERON:0015007 ! cervical vertebra endochondral element
intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue
relationship: develops_from UBERON:0013506 ! cervical vertebra pre-cartilage condensation
relationship: has_potential_to_develop_into UBERON:0002413 ! cervical vertebra

[Term]
id: UBERON:0013506
name: cervical vertebra pre-cartilage condensation
namespace: uberon
def: "A cervical vertebra endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic]
is_a: UBERON:0011095 ! vertebra pre-cartilage condensation
is_a: UBERON:0015007 ! cervical vertebra endochondral element
intersection_of: UBERON:0015007 ! cervical vertebra endochondral element
intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation

[Term]
id: UBERON:0013507
name: thoracic vertebra cartilage element
namespace: uberon
def: "A thoracic vertebra endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic]
synonym: "thoracic vertebral cartilage condensation group" EXACT [EHDAA2:0002014]
xref: EHDAA2:0002014
is_a: UBERON:0011094 ! vertebra cartilage element
is_a: UBERON:0015008 ! thoracic vertebra endochondral element
is_a: UBERON:2001457 ! postcranial axial cartilage
intersection_of: UBERON:0015008 ! thoracic vertebra endochondral element
intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue
relationship: develops_from UBERON:0013508 ! thoracic vertebra pre-cartilage condensation
relationship: has_potential_to_develop_into UBERON:0002347 ! thoracic vertebra

[Term]
id: UBERON:0013508
name: thoracic vertebra pre-cartilage condensation
namespace: uberon
def: "A thoracic vertebra endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic]
is_a: UBERON:0011095 ! vertebra pre-cartilage condensation
is_a: UBERON:0015008 ! thoracic vertebra endochondral element
intersection_of: UBERON:0015008 ! thoracic vertebra endochondral element
intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation

[Term]
id: UBERON:0013514
name: space surrounding organism
namespace: uberon
def: "The space that surrounds an organism." [https://orcid.org/0000-0002-6601-2165]
synonym: "external to organism" EXACT []
synonym: "outside of body" EXACT []
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: surrounds UBERON:0000468 ! multicellular organism
relationship: surrounds UBERON:0000468 ! multicellular organism

[Term]
id: UBERON:0013515
name: subdivision of oviduct
namespace: uberon
def: "A section through the tube or network of tubes that connects the ovaries to the outside of the body." [http://orcid.org/0000-0002-6601-2165]
subset: non_informative
synonym: "subdivision of fallopian tube" NARROW [FMA:18302]
synonym: "subdivision of oviduct" EXACT [FMA:18302]
synonym: "subdivision of uterine tube" EXACT []
synonym: "uterine tube zone" EXACT [FMA:18302]
synonym: "zone of uterine tube" EXACT [FMA:18302]
xref: FMA:18302
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0013522 ! subdivision of tube
intersection_of: UBERON:0013522 ! subdivision of tube
intersection_of: subdivision_of UBERON:0000993 ! oviduct
relationship: part_of UBERON:0000993 ! oviduct
relationship: subdivision_of UBERON:0000993 ! oviduct
property_value: UBPROP:0000012 "FMA class may only represent the uterine portion" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0013522
name: subdivision of tube
namespace: uberon
is_a: UBERON:0000064 ! organ part
relationship: has_part UBERON:0000060 ! anatomical wall
relationship: has_part UBERON:0000464 ! anatomical space
relationship: part_of UBERON:0000025 ! tube
relationship: subdivision_of UBERON:0000025 ! tube

[Term]
id: UBERON:0013525
name: stomach lumen
namespace: uberon
def: "The anatomical space that is enclosed by a stomach." [http://orcid.org/0000-0002-6601-2165]
synonym: "cavity of stomach" EXACT [FMA:14585]
synonym: "gastric cavity" RELATED [FMA:14585]
xref: EMAPA:18395
xref: FMA:14585
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000945 ! stomach
relationship: luminal_space_of UBERON:0000945 ! stomach
relationship: part_of UBERON:0000945 ! stomach
relationship: part_of UBERON:0011565 {source="FMA"} ! lumen of gastrointestinal system
property_value: UBPROP:0000001 "Organ cavity which is bound by the internal surface of the wall of stomach. Examples: There is only one cavity of stomach[FMA:14585]." xsd:string {source="FMA:14585"}

[Term]
id: UBERON:0013636
name: epithelium of intestinal villus
namespace: uberon
def: "An epithelium that is part of a intestinal villus." [OBOL:automatic]
synonym: "intestinal villus epithelium" EXACT [FMA:63587]
synonym: "villous epithelium" RELATED []
synonym: "villus epithelium" RELATED []
xref: FMA:63587
is_a: UBERON:0001902 ! epithelium of small intestine
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001213 ! intestinal villus
relationship: part_of UBERON:0001213 ! intestinal villus
relationship: part_of UBERON:0001902 {source="FMA"} ! epithelium of small intestine

[Term]
id: UBERON:0013685
name: foramen of skull
namespace: uberon
def: "Anatomical space that is an opening in a bone of the skull." [http://orcid.org/0000-0002-6601-2165, TAO:curator]
synonym: "cranial conduit" NARROW [FMA:53165]
synonym: "cranial foramen" NARROW []
synonym: "foramen of skull" EXACT [Wikipedia:Foramina_of_the_skull]
synonym: "foramina of the skull" RELATED OMO:0003004 [Wikipedia:Foramina_of_the_skull]
xref: FMA:53165
xref: SCTID:276742007
xref: Wikipedia:Foramina_of_the_skull
is_a: UBERON:0005744 ! bone foramen
intersection_of: UBERON:0005744 ! bone foramen
intersection_of: part_of UBERON:0003129 ! skull
relationship: part_of UBERON:0003129 ! skull

[Term]
id: UBERON:0013686
name: anatomical conduit space
namespace: uberon
def: "An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]." [FMA:9338, http://orcid.org/0000-0002-6601-2165]
subset: common_anatomy
synonym: "foramen space" NARROW []
xref: FMA:9338
is_a: UBERON:0000464 {source="FMA"} ! anatomical space
relationship: connects UBERON:0000464 {cardinality="2"} ! anatomical space
relationship: luminal_space_of UBERON:0004111 ! anatomical conduit
relationship: part_of UBERON:0004111 ! anatomical conduit
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0013694
name: brain endothelium
namespace: uberon
def: "Vascular endothelium found in blood vessels of the blood-brain-barrier." [CALOHA:TS-0092]
synonym: "cerebromicrovascular endothelium" RELATED [CALOHA:TS-0092]
xref: BTO:0001852
xref: BTO:0003248
xref: CALOHA:TS-0092
is_a: UBERON:0001986 ! endothelium
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0000955 ! brain
relationship: part_of UBERON:0000955 ! brain

[Term]
id: UBERON:0013695
name: colon endothelium
namespace: uberon
def: "Vascular endothelium found in colon blood vessels." [CALOHA:TS-0162]
synonym: "colon endothelial cell" RELATED [CALOHA:TS-0162]
synonym: "colon endothelial cells" RELATED [CALOHA:TS-0162]
synonym: "colonic endothelial cell" RELATED [CALOHA:TS-0162]
synonym: "colonic endothelium" RELATED [CALOHA:TS-0162]
synonym: "colorectal endothelial cell" RELATED [CALOHA:TS-0162]
synonym: "colorectal endothelium" RELATED [CALOHA:TS-0162]
xref: CALOHA:TS-0162
is_a: UBERON:0000397 ! colonic epithelium
is_a: UBERON:0001986 ! endothelium
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0001155 ! colon

[Term]
id: UBERON:0013697
name: exocrine pancreas epithelium
namespace: uberon
def: "Epithelium lining the exocrine pancreas." [CALOHA:TS-2108]
synonym: "epithelium of exocrine pancreas" RELATED [CALOHA:TS-2108]
synonym: "exocrine pancreas epithelial cell" RELATED [CALOHA:TS-2108]
xref: CALOHA:TS-2108
is_a: UBERON:0005911 ! endo-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000017 ! exocrine pancreas
relationship: part_of UBERON:0000017 ! exocrine pancreas

[Term]
id: UBERON:0013700
name: axial musculature
namespace: uberon
def: "Musculature of the head and neck, spine, and ribs." [HP:0003327]
xref: EHDAA2:0000159
xref: EMAPA:18166
is_a: UBERON:0001015 ! musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: attaches_to UBERON:0005944 ! axial skeleton plus cranial skeleton
intersection_of: part_of UBERON:0013701 ! main body axis
relationship: attaches_to UBERON:0005944 ! axial skeleton plus cranial skeleton
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0013701 ! main body axis

[Term]
id: UBERON:0013701
name: main body axis
namespace: uberon
def: "A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages." [https://orcid.org/0000-0002-6601-2165]
subset: non_informative
is_a: UBERON:0000475 ! organism subdivision
relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa

[Term]
id: UBERON:0013702
name: body proper
namespace: uberon
def: "The region of the organism associated with the visceral organs." [AEO:0000103]
subset: non_informative
synonym: "body" RELATED [AEO:0000103]
synonym: "whole body" RELATED [BTO:0001489]
xref: AEO:0000103
xref: BTO:0001489
xref: EMAPA:36031
xref: FMA:231424
is_a: UBERON:0000475 {source="AEO"} ! organism subdivision
relationship: part_of UBERON:0013701 ! main body axis
property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"}

[Term]
id: UBERON:0013704
name: notochordal canal
namespace: uberon
def: "A tubular passage that extends from the primitive pit into the head process during the early stages of embryonic development in mammals. It perforates the splanchnopleure layer so that the yolk sac and the amnion are connected temporarily." [http://medical-dictionary.thefreedictionary.com/notochordal+canal]
synonym: "chordal canal" RELATED []
xref: FMA:293127
xref: NCIT:C34230
xref: UMLS:C1518428 {source="ncithesaurus:Notochordal_Canal"}
is_a: UBERON:0004111 ! anatomical conduit
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0004111 ! anatomical conduit
intersection_of: part_of UBERON:0006268 ! notochordal process
relationship: part_of UBERON:0006268 ! notochordal process

[Term]
id: UBERON:0013727
name: notochordal fluid
namespace: uberon
def: "Fluid contained within the notochordal canal." [http://animaldiversity.org/accounts/Latimeria_chalumnae/, http://orcid.org/0000-0002-6601-2165]
comment: Distinct feature of coelocanths
synonym: "notochord fluid" EXACT []
synonym: "portion of notochordal fluid" EXACT []
is_a: UBERON:0006314 ! bodily fluid
intersection_of: UBERON:0006314 ! bodily fluid
intersection_of: located_in UBERON:0013704 ! notochordal canal
intersection_of: part_of UBERON:0036242 ! post-embryonic notochord
relationship: located_in UBERON:0013704 ! notochordal canal
relationship: part_of UBERON:0036242 ! post-embryonic notochord

[Term]
id: UBERON:0013754
name: integumentary system layer
namespace: uberon
def: "An organ component layer that is part of a integumental system." [OBOL:automatic]
subset: non_informative
synonym: "layer of skin" NARROW []
synonym: "skin layer" NARROW []
xref: SCTID:314820002
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: part_of UBERON:0002416 ! integumental system
relationship: part_of UBERON:0002416 ! integumental system

[Term]
id: UBERON:0013755
name: arterial blood
namespace: uberon
def: "A blood that is part of a artery." [OBOL:automatic]
subset: pheno_slim
synonym: "arterial blood" EXACT [FMA:83066]
synonym: "blood in artery" EXACT [FMA:83066]
synonym: "portion of arterial blood" EXACT [FMA:83066]
xref: BTO:0006188 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: FMA:83066
is_a: UBERON:0000178 ! blood
intersection_of: UBERON:0000178 ! blood
intersection_of: located_in UBERON:0001637 ! artery
relationship: located_in UBERON:0001637 ! artery

[Term]
id: UBERON:0013756
name: venous blood
namespace: uberon
def: "A blood that is part of a vein." [OBOL:automatic]
synonym: "blood in vein" EXACT [FMA:83067]
synonym: "portion of venous blood" EXACT [FMA:83067]
synonym: "venous blood" EXACT [FMA:83067]
xref: BTO:0006187 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
xref: FMA:83067
is_a: UBERON:0000178 ! blood
intersection_of: UBERON:0000178 ! blood
intersection_of: located_in UBERON:0001638 ! vein
relationship: located_in UBERON:0001638 ! vein

[Term]
id: UBERON:0013757
name: capillary blood
namespace: uberon
def: "A blood that is part of a capillary." [OBOL:automatic]
synonym: "blood in capillary" EXACT []
synonym: "portion of blood in capillary" EXACT [FMA:263901]
synonym: "portion of capillary blood" EXACT []
xref: FMA:263901
xref: NCIT:C32212
is_a: UBERON:0000178 ! blood
intersection_of: UBERON:0000178 ! blood
intersection_of: located_in UBERON:0001982 ! capillary
relationship: located_in UBERON:0001982 ! capillary

[Term]
id: UBERON:0013765
name: digestive system element
namespace: uberon
def: "Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
subset: pheno_slim
synonym: "digestive organ" EXACT []
synonym: "digestive system organ" EXACT []
xref: EMAPA:37843 {source="MA:th"}
xref: SCTID:272627002
is_a: UBERON:0000062 ! organ
intersection_of: UBERON:0000062 ! organ
intersection_of: part_of UBERON:0001007 ! digestive system
relationship: part_of UBERON:0001007 ! digestive system

[Term]
id: UBERON:0013768
name: great vessel of heart
namespace: uberon
def: "Great vessels is a term used to refer collectively to the large vessels that bring blood to and from the heart." [Wikipedia:Great_vessels]
comment: Groupings may vary - typically pulmonary vessels and aorta and vena cavae
subset: grouping_class
synonym: "great vessel" BROAD []
synonym: "great vessel of thorax" EXACT []
xref: EMAPA:36460
xref: SCTID:304066000
xref: Wikipedia:Great_vessels
is_a: UBERON:0001981 ! blood vessel

[Term]
id: UBERON:0013769
name: uterine lumen
namespace: uberon
def: "An organ cavity that is part of a uterus." [OBOL:automatic]
synonym: "cavity of uterus" EXACT [FMA:17745]
synonym: "uterine cavity" EXACT [FMA:17745]
synonym: "uterine space" EXACT []
xref: EMAPA:36273
xref: FMA:17745
xref: Wikipedia:Uterine_cavity
is_a: UBERON:0002558 ! organ cavity
intersection_of: UBERON:0002558 ! organ cavity
intersection_of: part_of UBERON:0000995 ! uterus
relationship: part_of UBERON:0000995 ! uterus

[Term]
id: UBERON:0014387
name: mesenchyme derived from neural crest
namespace: uberon
def: "Mesenchyme that develops_from the neural crest[Automatically generated definition]." [https://github.com/obophenotype/uberon/issues/248, OBOL:automatic]
synonym: "mesenchyme from neural crest" EXACT []
synonym: "neural crest derived mesenchyme" EXACT []
synonym: "neural crest mesenchyme" EXACT []
xref: EMAPA:32735
xref: FMA:293883
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: develops_from UBERON:0002342 ! neural crest

[Term]
id: UBERON:0014388
name: kidney collecting duct epithelium
namespace: uberon
def: "The simple cuboidal epithelium lining the lumen of kidney collecting ducts." [MGI:anna, MP:0011843]
subset: pheno_slim
synonym: "collecting duct of renal tubule epithelium" EXACT []
synonym: "epithelium of collecting duct of renal tubule" EXACT []
synonym: "epithelium of renal collecting tubule" EXACT []
xref: EMAPA:37885 {source="MA:th"}
is_a: UBERON:0000484 ! simple cuboidal epithelium
is_a: UBERON:0004211 ! nephron epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule
relationship: contributes_to_morphology_of UBERON:0001232 ! collecting duct of renal tubule
relationship: part_of UBERON:0001232 ! collecting duct of renal tubule
property_value: UBPROP:0000008 "In mouse, the mature and differentiated CD epithelium comprises two unique cells types with principal cells responsible for vasopressin-regulated water reabsorption, and intercalated cells regulating acid-base homeostasis; injury to the epithelium is believed to cause epithelial cells to acquire mesenchymal characteristics via epithelial-mesenchymal transition (EMT), a process through which tubular epithelial cells may transform into interstitial fibroblasts and promote renal fibrosis" xsd:string

[Term]
id: UBERON:0014398
name: respiratory muscle
namespace: uberon
def: "Muscle that is part of the respiratory system." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
xref: MESH:D012132 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"}
is_a: UBERON:0003831 ! respiratory system muscle
intersection_of: UBERON:0001630 ! muscle organ
intersection_of: capable_of_part_of GO:0007585 ! respiratory gaseous exchange by respiratory system
relationship: capable_of_part_of GO:0007585 ! respiratory gaseous exchange by respiratory system
relationship: composed_primarily_of UBERON:0001134 ! skeletal muscle tissue
property_value: curator_notes "this class may be merged with 'respiratory system muscle'; check intercostals" xsd:string

[Term]
id: UBERON:0014399
name: sinusoidal space
namespace: uberon
def: "An anatomical space that is enclosed by a sinusoid." [OBOL:automatic]
synonym: "lumen of sinusoid" EXACT [FMA:63133]
synonym: "sinusoid lumen" EXACT [FMA:63133]
xref: FMA:63133
is_a: UBERON:0010161 ! lumen of blood vessel
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0003909 ! sinusoid
relationship: luminal_space_of UBERON:0003909 ! sinusoid
relationship: part_of UBERON:0003909 ! sinusoid

[Term]
id: UBERON:0014400
name: hepatic sinusoidal space
namespace: uberon
def: "A sinusoidal space that is part of a hepatic sinusoid." [OBOL:automatic]
synonym: "lumen of hepatic sinusoid" EXACT [FMA:262090]
xref: FMA:262090
is_a: UBERON:0014399 ! sinusoidal space
intersection_of: UBERON:0014399 ! sinusoidal space
intersection_of: part_of UBERON:0001281 ! hepatic sinusoid
relationship: part_of UBERON:0001281 ! hepatic sinusoid

[Term]
id: UBERON:0014401
name: renal venous blood vessel
namespace: uberon
def: "Any member of the network of tubes that return blood from the renal tissues to the systemic circulation." [MGI:csmith]
subset: pheno_slim
synonym: "kidney venous blood vessel" EXACT [MA:0002591]
synonym: "kidney venous system" RELATED [EMAPA:31450]
synonym: "venous blood vessel of kidney" EXACT []
xref: EMAPA:31450
xref: MA:0002591
is_a: UBERON:0003517 ! kidney blood vessel
is_a: UBERON:0003920 ! venous blood vessel
intersection_of: UBERON:0003920 ! venous blood vessel
intersection_of: part_of UBERON:0002113 ! kidney
property_value: UBPROP:0000012 "we follow MA and MP in distinguishing the venous blood vessel from the vein. The kidney cortex vein is not considered a renal vein, nor is the vasa recta" xsd:string {external_ontology="MA"}

[Term]
id: UBERON:0014402
name: sex-specific anatomical structure
namespace: uberon
def: "A part of the body present only in a specific gender." [AEO:0000174, AEO:JB]
synonym: "gender-specific" EXACT []
synonym: "gender-specific anatomical structure" EXACT [AEO:0000174]
synonym: "sex-specific" EXACT []
xref: AEO:0000174
xref: WBbt:0005752
is_a: UBERON:0000061 ! anatomical structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: output_of GO:0007548 ! sex differentiation
relationship: output_of GO:0007548 ! sex differentiation

[Term]
id: UBERON:0014403
name: male anatomical structure
namespace: uberon
def: "A part of the body present only in males." [AEO:0000175, AEO:JB]
synonym: "male-specific" RELATED [WBbt:0005757]
synonym: "male-specific structure" EXACT []
xref: AEO:0000175
xref: WBbt:0005757
is_a: UBERON:0014402 ! sex-specific anatomical structure
intersection_of: UBERON:0014402 ! sex-specific anatomical structure
intersection_of: part_of UBERON:0003101 ! male organism
relationship: part_of UBERON:0003101 ! male organism

[Term]
id: UBERON:0014404
name: female anatomical structure
namespace: uberon
def: "A part of the body present only in females." [AEO:0000176, AEO:JB]
xref: AEO:0000176
is_a: UBERON:0014402 ! sex-specific anatomical structure
intersection_of: UBERON:0014402 ! sex-specific anatomical structure
intersection_of: part_of UBERON:0003100 ! female organism
relationship: part_of UBERON:0003100 ! female organism

[Term]
id: UBERON:0014454
name: visceral abdominal adipose tissue
namespace: uberon
def: "Subcutaneous adipose tissue that is located in the peritoneal cavity." [CALOHA:paula, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/259, MGI:csmith]
synonym: "abdominal fat" RELATED [BTO:0004041]
synonym: "intra-abdominal adipose tissue" RELATED []
synonym: "intra-abdominal fat" RELATED [BTO:0004041]
synonym: "organ fat" RELATED [BTO:0004041]
synonym: "visceral adipose tissue" RELATED [BTO:0004041]
synonym: "visceral fat" RELATED [BTO:0004041]
xref: BTO:0004041
xref: CALOHA:TS-2405
is_a: UBERON:0007808 ! adipose tissue of abdominal region
intersection_of: UBERON:0001013 ! adipose tissue
intersection_of: bounding_layer_of UBERON:0002075 ! viscus
intersection_of: located_in UBERON:0001179 ! peritoneal cavity
intersection_of: part_of UBERON:0000916 ! abdomen
relationship: bounding_layer_of UBERON:0002075 ! viscus
relationship: located_in UBERON:0001179 ! peritoneal cavity
relationship: part_of UBERON:0002075 ! viscus
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cindyJax
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/paulacalipho
property_value: UBPROP:0000001 "Adipose tissue located inside the peritoneal cavity, packed in between internal organs and torso. An excess of visceral fat is known as central obesity, or belly fat, the pot belly or beer belly effect, in which the abdomen protrudes excessively[BTO:0004041]." xsd:string {source="BTO:0004041"}

[Term]
id: UBERON:0014455
name: subcutaneous abdominal adipose tissue
namespace: uberon
def: "Subcutaneous adipose tissue that is located in the abdominal region." [CALOHA:paula, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/259, MGI:csmith]
synonym: "abdominal subcutaneous adipose tissue" EXACT []
synonym: "subcutaneous abdominal fat" EXACT []
synonym: "subcutaneous fat of abdominal region" EXACT []
xref: CALOHA:TS-2406
is_a: UBERON:0002190 ! subcutaneous adipose tissue
is_a: UBERON:0007808 ! adipose tissue of abdominal region
intersection_of: UBERON:0001013 ! adipose tissue
intersection_of: part_of UBERON:0000916 ! abdomen
intersection_of: part_of UBERON:0002072 ! hypodermis
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cindyJax
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/paulacalipho

[Term]
id: UBERON:0014477
name: thoracic skeleton
namespace: uberon
def: "Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Rib_cage]
subset: human_reference_atlas
subset: pheno_slim
synonym: "skeleton of thorax" EXACT []
synonym: "thoracic part of axial skeleton" EXACT []
synonym: "thoracic skeleton" EXACT [EHDAA2:0002013]
xref: EHDAA2:0002013
xref: FMA:77169
xref: Wikipedia:Thoracic_skeleton
is_a: UBERON:0010912 ! subdivision of skeleton
relationship: part_of UBERON:0000915 ! thoracic segment of trunk
relationship: part_of UBERON:0002090 ! postcranial axial skeleton
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0014610
name: thoracic spinal cord ventral horn
namespace: uberon
def: "A ventral horn of spinal cord that is part of a thoracic spinal cord." [OBOL:automatic]
subset: human_reference_atlas
synonym: "thoracic spinal cord anterior horn" RELATED [BIRNLEX:1410]
synonym: "thoracic spinal cord ventral horn" EXACT HUMAN_PREFERRED [BIRNLEX:1410]
xref: BIRNLEX:1410
xref: SCTID:367876000
xref: UMLS:C0228632 {source="BIRNLEX:1410"}
xref: UMLS:C1288552 {source="BIRNLEX:1410"}
is_a: UBERON:0002257 ! ventral horn of spinal cord
intersection_of: UBERON:0002257 ! ventral horn of spinal cord
intersection_of: part_of UBERON:0003038 ! thoracic spinal cord
relationship: part_of UBERON:0003038 ! thoracic spinal cord
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0014613
name: cervical spinal cord gray matter
namespace: uberon
def: "A gray matter of spinal cord that is part of a cervical spinal cord." [OBOL:automatic]
subset: human_reference_atlas
synonym: "cervical spinal cord gray matter" EXACT HUMAN_PREFERRED [BIRNLEX:1521]
xref: BIRNLEX:1521
xref: SCTID:362438009
xref: UMLS:C0228610 {source="BIRNLEX:1521"}
is_a: UBERON:0002315 ! gray matter of spinal cord
intersection_of: UBERON:0002315 ! gray matter of spinal cord
intersection_of: part_of UBERON:0002726 ! cervical spinal cord
relationship: part_of UBERON:0002726 ! cervical spinal cord
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0014621
name: cervical spinal cord ventral horn
namespace: uberon
def: "A ventral horn of spinal cord that is part of a cervical spinal cord." [OBOL:automatic]
subset: human_reference_atlas
synonym: "cervical spinal cord anterior horn" RELATED [BIRNLEX:1680]
synonym: "cervical spinal cord ventral horn" EXACT HUMAN_PREFERRED [BIRNLEX:1680]
xref: BIRNLEX:1680
xref: MESH:D066151 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"}
xref: SCTID:174363005
xref: UMLS:C0228615 {source="BIRNLEX:1680"}
xref: UMLS:C1278740 {source="BIRNLEX:1680"}
is_a: UBERON:0002257 ! ventral horn of spinal cord
intersection_of: UBERON:0002257 ! ventral horn of spinal cord
intersection_of: part_of UBERON:0002726 ! cervical spinal cord
relationship: part_of UBERON:0002726 ! cervical spinal cord
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0014636
name: thoracic spinal cord gray matter
namespace: uberon
def: "A gray matter of spinal cord that is part of a thoracic spinal cord." [OBOL:automatic]
subset: human_reference_atlas
synonym: "thoracic spinal cord gray matter" EXACT HUMAN_PREFERRED [BIRNLEX:980]
xref: BIRNLEX:980
xref: SCTID:362441000
xref: UMLS:C0228627 {source="BIRNLEX:980"}
is_a: UBERON:0002315 ! gray matter of spinal cord
intersection_of: UBERON:0002315 ! gray matter of spinal cord
intersection_of: part_of UBERON:0003038 ! thoracic spinal cord
relationship: part_of UBERON:0003038 ! thoracic spinal cord
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0014699
name: extraembryonic venous system
namespace: uberon
def: "A venous system that overlaps a umbilical cord and is part of a entire extraembryonic component." [OBOL:automatic]
xref: EHDAA2:0000479
xref: EMAPA:16374
xref: VHOG:0000282
is_a: UBERON:0004582 ! venous system
is_a: UBERON:0014701 {source="VHOG"} ! extraembryonic vascular system
intersection_of: UBERON:0004582 ! venous system
intersection_of: overlaps UBERON:0002331 ! umbilical cord
intersection_of: part_of UBERON:0016887 ! entire extraembryonic component

[Term]
id: UBERON:0014701
name: extraembryonic vascular system
namespace: uberon
def: "A vascular system that overlaps a umbilical cord and is part of a entire extraembryonic component." [OBOL:automatic]
xref: EHDAA2:0000478
xref: EMAPA:16370
xref: VHOG:0001396
is_a: UBERON:0007798 ! vascular system
intersection_of: UBERON:0007798 ! vascular system
intersection_of: overlaps UBERON:0002331 ! umbilical cord
intersection_of: part_of UBERON:0016887 ! entire extraembryonic component
relationship: overlaps UBERON:0002331 ! umbilical cord
relationship: part_of UBERON:0016887 ! entire extraembryonic component

[Term]
id: UBERON:0014702
name: frontonasal process epithelium
namespace: uberon
def: "An epithelium that is part of a frontonasal prominence." [OBOL:automatic]
xref: EHDAA2:0004108
xref: EMAPA:32918
is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0004066 ! frontonasal prominence
relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm
relationship: part_of UBERON:0004066 ! frontonasal prominence

[Term]
id: UBERON:0014703
name: anal membrane ectodermal component
namespace: uberon
def: "A unilaminar epithelium that develops_from a ectoderm and is part of a anal region." [OBOL:automatic]
xref: EHDAA2:0004019
xref: EMAPA:25040
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0000490 ! unilaminar epithelium
intersection_of: develops_from UBERON:0000924 ! ectoderm
intersection_of: part_of UBERON:0001353 ! anal region
relationship: part_of UBERON:0001353 ! anal region

[Term]
id: UBERON:0014704
name: pleuroperitoneal canal lumen
namespace: uberon
def: "An anatomical space that is enclosed by a pleuroperitoneal canal." [OBOL:automatic]
synonym: "pleuro-peritoneal canal cavity" EXACT [EMAPA:25034]
xref: EHDAA2:0004736
xref: EMAPA:25034
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0006279 ! pleuroperitoneal canal
relationship: develops_from UBERON:0002323 {source="EHDAA2"} ! coelemic cavity lumen
relationship: luminal_space_of UBERON:0006279 ! pleuroperitoneal canal
relationship: part_of UBERON:0006279 ! pleuroperitoneal canal

[Term]
id: UBERON:0014706
name: primitive renal collecting duct system
namespace: uberon
synonym: "metanephros primitive collecting ducts" EXACT [EHDAA2:0001147]
synonym: "primitive collecting duct" EXACT [EMAPA:17646]
xref: EHDAA2:0001147
xref: EMAPA:17646
is_a: UBERON:0007501 {source="EHDAA2"} ! arborizing epithelial duct system
is_a: UBERON:0012275 ! meso-epithelium
relationship: develops_from UBERON:0000084 {source="EHDAA2"} ! ureteric bud

[Term]
id: UBERON:0014716
name: interlobular duct
namespace: uberon
def: "A duct that is located between lobules, within the thin connective tissue septa that separate lobules. All interlobular ducts are excretory." [ncithesaurus:Interlobular_Duct]
subset: human_reference_atlas
xref: NCIT:C32828
xref: UMLS:C1512857
xref: Wikipedia:Interlobular_ducts
is_a: UBERON:0035050 ! excretory duct
intersection_of: UBERON:0000058 ! duct
intersection_of: connected_to UBERON:0009911 ! lobule
intersection_of: part_of UBERON:0002384 ! connective tissue
relationship: connected_to UBERON:0009911 ! lobule
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0002384 ! connective tissue
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0014717
name: mucous acinus
namespace: uberon
def: "The secretory unit of a mucous gland. The acinar portion is composed of mucous secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm]
synonym: "acinus of mucuous gland" EXACT []
synonym: "mucus acinus" EXACT []
xref: FMA:86278
is_a: UBERON:0011858 ! acinus of exocrine gland
intersection_of: UBERON:0009842 ! glandular acinus
intersection_of: part_of UBERON:0000414 ! mucous gland
relationship: composed_primarily_of CL:0000319 ! mucus secreting cell
relationship: part_of UBERON:0000414 ! mucous gland

[Term]
id: UBERON:0014719
name: intralobular duct
namespace: uberon
def: "A duct that is located within a lobule, with no more connective tissue intervening between ducts and secretory units (i.e., acini or tubules) than between adjacent secretory units. Intercalated and striated ducts are intralobular." [http://www.siumed.edu/~dking2/intro/glands.htm]
subset: human_reference_atlas
synonym: "intralobular ductule" RELATED []
xref: SCTID:205214009
is_a: UBERON:0000058 ! duct
intersection_of: UBERON:0000058 ! duct
intersection_of: part_of UBERON:0009911 ! lobule
relationship: part_of UBERON:0009911 ! lobule
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0014720
name: interlobar duct
namespace: uberon
def: "A duct that is located between lobes, within conspicuous, thick connective tissue septa that separate lobes. All interlobar ducts are excretory." [http://www.siumed.edu/~dking2/intro/glands.htm]
synonym: "intralobular ductule" RELATED []
is_a: UBERON:0035050 ! excretory duct
intersection_of: UBERON:0000058 ! duct
intersection_of: connects UBERON:0009912 ! anatomical lobe
intersection_of: part_of UBERON:0002384 ! connective tissue
relationship: connects UBERON:0009912 ! anatomical lobe
relationship: part_of UBERON:0002384 ! connective tissue

[Term]
id: UBERON:0014776
name: midbrain neuromere
namespace: uberon
def: "A neuromere that is part of the presumptive midbrain." [http://orcid.org/0000-0002-6601-2165]
synonym: "future mesencephalon" RELATED []
synonym: "mesomere" BROAD []
synonym: "mesomere group" RELATED [EHDAA2:0004352]
synonym: "mesomere of nervous system" EXACT []
synonym: "midbrain segment" BROAD []
synonym: "neuromere of mesomere group" EXACT []
synonym: "segment of midbrain" BROAD []
xref: EHDAA2:0004352
xref: FMA:61997
is_a: UBERON:0004731 ! neuromere
intersection_of: UBERON:0004731 ! neuromere
intersection_of: part_of UBERON:0009616 ! presumptive midbrain
relationship: part_of UBERON:0009616 ! presumptive midbrain

[Term]
id: UBERON:0014777
name: spinal neuromere
namespace: uberon
def: "A neuromere that is part of the presumptive spinal cord." [http://orcid.org/0000-0002-6601-2165]
synonym: "spinal cord metameric segment" EXACT []
synonym: "spinal cord segment" RELATED [TAO:0001332]
synonym: "spinal neuromeres" EXACT OMO:0003004 [TAO:0001332]
xref: TAO:0001332
xref: ZFA:0001332
is_a: UBERON:0004731 ! neuromere
intersection_of: UBERON:0004731 ! neuromere
intersection_of: part_of UBERON:0006241 ! future spinal cord
relationship: part_of UBERON:0006241 ! future spinal cord

[Term]
id: UBERON:0014783
name: cloacal muscle
namespace: uberon
def: "Any muscle organ that is part of a cloaca." [OBOL:automatic]
is_a: UBERON:0001630 ! muscle organ
is_a: UBERON:0013765 ! digestive system element
intersection_of: UBERON:0001630 ! muscle organ
intersection_of: part_of UBERON:0000162 ! cloaca
relationship: part_of UBERON:0000162 ! cloaca

[Term]
id: UBERON:0014792
name: musculature of pelvic complex
namespace: uberon
def: "Any collection of muscles that is part of a pelvic complex. The pelvic complex comprises the pelvic girdle and the associated limb or fin." [OBOL:automatic]
synonym: "muscles of lower limb" NARROW [FMA:71297]
synonym: "musculature of lower limb" NARROW [FMA:71297]
synonym: "musculi membri inferioris" NARROW [FMA:TA]
xref: EMAPA:37864 {source="MA:th"}
xref: FMA:71297
is_a: UBERON:0001015 ! musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0010709 ! pelvic complex
relationship: part_of UBERON:0010709 ! pelvic complex
property_value: editor_note "currently defined by location rather than attachment" xsd:string

[Term]
id: UBERON:0014793
name: musculature of pectoral complex
namespace: uberon
def: "Any collection of muscles that is part of a pectoral complex. The pectoral complex comprises the pectoral girdle and the associated limb or fin." [OBOL:automatic]
synonym: "muscles of upper limb" NARROW [FMA:71296]
synonym: "musculature of upper limb" NARROW [FMA:71296]
synonym: "musculi membri superioris" NARROW [FMA:TA]
synonym: "set of muscles of upper limb" NARROW [FMA:71296]
synonym: "upper limb musculature" NARROW [FMA:71296]
xref: EMAPA:37861 {source="MA:th"}
xref: FMA:71296
is_a: UBERON:0001015 ! musculature
intersection_of: UBERON:0001015 ! musculature
intersection_of: part_of UBERON:0010708 ! pectoral complex
relationship: part_of UBERON:0010708 ! pectoral complex
property_value: editor_note "currently defined by location rather than attachment" xsd:string

[Term]
id: UBERON:0014794
name: pectoral appendage muscle
namespace: uberon
def: "Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin)." [OBOL:automatic]
is_a: UBERON:0010891 ! pectoral complex muscle
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0004710 ! pectoral appendage
relationship: part_of UBERON:0007269 {source="prolog"} ! pectoral appendage musculature

[Term]
id: UBERON:0014795
name: pelvic appendage muscle
namespace: uberon
def: "Any muscle organ that is part of a pelvic appendage (hindlimb or pelvic fin)." [OBOL:automatic]
is_a: UBERON:0010890 ! pelvic complex muscle
intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate
intersection_of: part_of UBERON:0004709 ! pelvic appendage
relationship: part_of UBERON:0007270 {source="prolog"} ! pelvic appendage musculature

[Term]
id: UBERON:0014892
name: skeletal muscle organ, vertebrate
namespace: uberon
def: "A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles)." [GOC:dos]
subset: human_reference_atlas
synonym: "skeletal muscle" BROAD []
xref: AAO:0011099
xref: BTO:0001103
xref: CALOHA:TS-0933
xref: EFO:0000888
xref: EHDAA:5035
xref: EHDAA:5043
xref: EHDAA:5978
xref: EHDAA:5984
xref: EMAPA:35988
xref: EV:0100377
xref: GAID:141
xref: MA:0003148
xref: MAT:0000302
xref: MESH:D018482
xref: MIAA:0000302
xref: TAO:0005277
xref: VHOG:0000319
xref: XAO:0000174
xref: ZFA:0005277
is_a: UBERON:0001630 ! muscle organ
intersection_of: UBERON:0001630 ! muscle organ
intersection_of: composed_primarily_of UBERON:0001134 ! skeletal muscle tissue
intersection_of: develops_from UBERON:0003082 ! myotome
intersection_of: surrounded_by UBERON:0011899 ! epimysium
intersection_of: synapsed_by CL:0000100 ! motor neuron
relationship: composed_primarily_of UBERON:0001134 ! skeletal muscle tissue
relationship: develops_from UBERON:0003082 ! myotome
relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata <vertebrates>
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0018254 ! skeletal musculature
relationship: surrounded_by UBERON:0011899 ! epimysium
relationship: synapsed_by CL:0000100 ! motor neuron
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0014895
name: somatic muscle
name: somatic muscle, invertebrate
namespace: uberon
def: "A muscle structure of invertebrates whose origin and insertion sites are in basal side of the epidermis or structures derived from it. The simplest somatic muscles consist of a single cell and associated extracellular structures." [GOC:DOS]
synonym: "skeletal muscle" RELATED [FBbt:00005073]
xref: HAO:0001922
is_a: UBERON:0005090 ! muscle structure
relationship: attaches_to UBERON:0002416 ! integumental system
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0007095 ! somatic musculature
property_value: RO:0002161 NCBITaxon:7742
property_value: RO:0002175 NCBITaxon:50557
property_value: UBPROP:0000001 "The muscle that is attached at either end to the cuticle[HAO]." xsd:string {source="HAO:0001922", source="http://api.hymao.org/api/ref/67791"}

[Term]
id: UBERON:0014903
name: primordial vasculature
namespace: uberon
def: "A portion of tissue that will develop into vasculature." [ZFA:0005076, ZFA:curator]
xref: EFO:0003708
xref: TAO:0005076
xref: ZFA:0005076
is_a: UBERON:0001048 ! primordium
intersection_of: UBERON:0001048 ! primordium
intersection_of: has_potential_to_develop_into UBERON:0002049 ! vasculature
relationship: has_potential_to_develop_into UBERON:0002049 ! vasculature
relationship: part_of UBERON:0011695 ! embryonic cardiovascular system

[Term]
id: UBERON:0014907
name: intersomitic vessel
namespace: uberon
def: "One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites." [MGI:anna]
subset: pheno_slim
synonym: "intersegmental vessel" EXACT [ZFA:0001285]
synonym: "intersegmental vessels" EXACT OMO:0003004 [ZFA:0001285]
synonym: "intersomitic blood vessel" EXACT [XAO:0004075]
synonym: "intersomitic vessels" EXACT OMO:0003004 [ZFA:0001285]
synonym: "segmental vessel" EXACT [ZFA:0001285]
xref: EFO:0003664
xref: EMAPA:37389 {source="MA:th"}
xref: TAO:0001285
xref: XAO:0004075
xref: ZFA:0001285
is_a: UBERON:0001981 {source="ZFA"} ! blood vessel
relationship: develops_from UBERON:0005805 {source="ZFA"} ! dorsal aorta
property_value: UBPROP:0000001 "Blood vessels that connect the dorsal aorta or the posterior cardinal vein and the dorsal longitudinal anastomotic vessel. They run along the vertical myotomal boundaries. At early stages these don't have venous or arterial markers[ZFA:0001285, ZFIN:ZDB-PUB-030908-4]." xsd:string {source="ZFA:0001285, ZFIN:ZDB-PUB-030908-4"}

[Term]
id: UBERON:0015007
name: cervical vertebra endochondral element
namespace: uberon
def: "A vertebral endochondral element in the cervical region of the vertebral column." [http://orcid.org/0000-0002-6601-2165]
synonym: "cervical vertebra element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern]
synonym: "cervical vertebra skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern]
is_a: UBERON:0005174 ! dorsal region element
is_a: UBERON:0010913 ! vertebral element
intersection_of: UBERON:0010913 ! vertebral element
intersection_of: part_of UBERON:0006072 ! cervical region of vertebral column
union_of: UBERON:0002413 ! cervical vertebra
union_of: UBERON:0013505 ! cervical vertebra cartilage element
union_of: UBERON:0013506 ! cervical vertebra pre-cartilage condensation
relationship: part_of UBERON:0006072 ! cervical region of vertebral column

[Term]
id: UBERON:0015008
name: thoracic vertebra endochondral element
namespace: uberon
def: "A vertebral endochondral element in the thoracic region of the vertebral column." [http://orcid.org/0000-0002-6601-2165]
synonym: "thoracic vertebra element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern]
synonym: "thoracic vertebra skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern]
is_a: UBERON:0005174 ! dorsal region element
is_a: UBERON:0005181 ! thoracic segment organ
is_a: UBERON:0010913 ! vertebral element
intersection_of: UBERON:0010913 ! vertebral element
intersection_of: part_of UBERON:0006073 ! thoracic region of vertebral column
union_of: UBERON:0002347 ! thoracic vertebra
union_of: UBERON:0013507 ! thoracic vertebra cartilage element
union_of: UBERON:0013508 ! thoracic vertebra pre-cartilage condensation
relationship: part_of UBERON:0006073 ! thoracic region of vertebral column

[Term]
id: UBERON:0015060
name: sphenoid endochondral element
namespace: uberon
def: "A sphenoid bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern]
synonym: "sphenoid bone skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern]
synonym: "sphenoid element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern]
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0010363 ! endochondral element
union_of: UBERON:0001677 ! sphenoid bone
union_of: UBERON:0009191 ! sphenoid bone pre-cartilage condensation
union_of: UBERON:0009193 ! sphenoid cartilage element
relationship: part_of UBERON:0011156 ! facial skeleton

[Term]
id: UBERON:0015128
name: subepicardial layer of epicardium
namespace: uberon
synonym: "perimysial connective tissue of subepicardium" EXACT [FMA:83105]
synonym: "subepicardial connective tissue" EXACT [FMA:83105]
xref: FMA:83105
is_a: UBERON:0007188 ! mesothelium of serous pericardium
relationship: part_of UBERON:0002348 {source="FMA"} ! epicardium
property_value: editor_note "consider merging into myocardial compact layer" xsd:string

[Term]
id: UBERON:0015129
name: epicardial fat
namespace: uberon
def: "Visceral intrapericardial fat contiguous with the myocardial surface." [DOI:10.5935/abc.20130138]
synonym: "epicardial adipose tissue" EXACT []
synonym: "pericardial adipose tissue" EXACT []
xref: FMA:9871
xref: SCTID:42267001
is_a: UBERON:0003837 ! thoracic segment connective tissue
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0035814 ! pericardial fat
intersection_of: UBERON:0001013 ! adipose tissue
intersection_of: adjacent_to UBERON:0002348 ! epicardium
intersection_of: adjacent_to UBERON:0002425 ! visceral serous pericardium
intersection_of: surrounds UBERON:0000948 ! heart
relationship: adjacent_to UBERON:0002348 ! epicardium
relationship: adjacent_to UBERON:0002425 ! visceral serous pericardium
relationship: composed_primarily_of CL:1000309 ! epicardial adipocyte
relationship: part_of UBERON:0015128 ! subepicardial layer of epicardium

[Term]
id: UBERON:0015152
name: gland of ocular region
namespace: uberon
def: "A gland that is typically found in or near the orbital region, in or around either the medial or lateral canthi, and is typically associated with secretions onto the eyeball or associated ducts. Includes the Harderian, nictitans and lacrimal glands." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/614]
synonym: "ocular gland" EXACT []
synonym: "orbital gland" RELATED []
is_a: UBERON:0002530 ! gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0004088 ! orbital region
relationship: part_of UBERON:0035639 {source="inferred"} ! ocular adnexa
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: UBPROP:0000008 "the only orbital gland found in anuran amphibians is either the Harderian or the lacrimal; if it is a lacrimal, then a progressive lateral migration of the lacrimal glands must occur through the amniotes[PMID:7559104]" xsd:string
property_value: UBPROP:0000008 "the only orbital gland found in anuran amphibians is the Harderian[PMID:8843648]" xsd:string

[Term]
id: UBERON:0015165
name: multi-unit eye
namespace: uberon
def: "An eye consisting of multiple light-sensing organs." [http://orcid.org/0000-0002-6601-2165, PMID:21062451]
is_a: UBERON:0000970 ! eye
intersection_of: UBERON:0000970 ! eye
intersection_of: composed_primarily_of UBERON:0000020 ! sense organ
relationship: composed_primarily_of UBERON:0000020 ! sense organ
property_value: RO:0002161 NCBITaxon:7742
property_value: RO:0002175 NCBITaxon:6340 {notes="present on tentacular crown", source="PMID:21062451"}
property_value: RO:0002175 NCBITaxon:6544 {notes="present on mantle edge in arcacean Bivalvia", source="PMID:21062451"}
property_value: RO:0002175 NCBITaxon:7588 {notes="The eyes (optic cushions) on the oral surface of Asteroida (Echinodermata), close to the base of the terminal tentacles, are also composed of a number of simple ocelli - as many as 80-200 in certain species", source="PMID:21062451"}

[Term]
id: UBERON:0015172
name: endometrial blood vessel
namespace: uberon
def: "A blood vessel that is part of a endometrium." [OBOL:automatic]
subset: human_reference_atlas
synonym: "blood vessel of endometrium" EXACT []
xref: SCTID:254200009
is_a: UBERON:0001981 ! blood vessel
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0001295 ! endometrium
relationship: part_of UBERON:0001295 ! endometrium
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0015178
name: somite border
namespace: uberon
def: "A region of somite adjacent to presomitic mesoderm." [http://orcid.org/0000-0002-6601-2165]
subset: pheno_slim
synonym: "inter-somited border" RELATED []
synonym: "intersomitic boundary" RELATED []
synonym: "intersomitic fissure" RELATED []
synonym: "intersomitic junction" RELATED [XAO:0004074]
synonym: "segmental border" RELATED []
synonym: "somite boundary" RELATED [ZFA:0001462]
xref: TAO:0001462
xref: XAO:0004074
xref: ZFA:0001462
is_a: UBERON:0007651 ! anatomical junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: adjacent_to UBERON:0003059 ! presomitic mesoderm
intersection_of: part_of UBERON:0002329 ! somite
relationship: adjacent_to UBERON:0003059 ! presomitic mesoderm
relationship: part_of UBERON:0002329 ! somite

[Term]
id: UBERON:0015179
name: somite boundary epithelium
namespace: uberon
def: "Epithelium located in the intersomitic region." [XAO:0004077, XAO:EJS]
synonym: "intersomitic epithelium" EXACT [XAO:0004077]
synonym: "intersomitic membrane" EXACT [XAO:0004077]
xref: XAO:0004077
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0015178 ! somite border
relationship: part_of UBERON:0015178 ! somite border

[Term]
id: UBERON:0015203
name: non-connected functional system
namespace: uberon
def: "An anatomical group whose component structures share a common function." [AEO:0000093, AEO:JB, FBbt:00007278, FBC:DOS]
xref: AEO:0000093
xref: FBbt:00007278 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0034923 ! disconnected anatomical group

[Term]
id: UBERON:0015204
name: glandular system
namespace: uberon
def: "A non-connected functional system that is composed primarily of a gland." [OBOL:automatic]
xref: EHDAA2:0002223
is_a: UBERON:0015203 ! non-connected functional system
intersection_of: UBERON:0015203 ! non-connected functional system
intersection_of: composed_primarily_of UBERON:0002530 ! gland
relationship: composed_primarily_of UBERON:0002530 ! gland

[Term]
id: UBERON:0015212
name: lateral structure
namespace: uberon
def: "Any structure that is placed on one side of the left-right axis of a bilaterian." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
subset: non_informative
is_a: UBERON:0000061 ! anatomical structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: in_lateral_side_of UBERON:0000465 ! material anatomical entity
relationship: in_lateral_side_of UBERON:0000465 ! material anatomical entity
relationship: only_in_taxon NCBITaxon:33213 ! Bilateria
relationship: part_of UBERON:0000465 ! material anatomical entity
property_value: curator_notes "This class is primarily to implement taxon constraints. It may be removed in the future." xsd:string

[Term]
id: UBERON:0015214
name: arcuate ligament
namespace: uberon
def: "A ligament that is part of a diaphragm." [OBOL:automatic]
xref: EMAPA:19236
xref: FMA:58280
is_a: UBERON:0000211 ! ligament
is_a: UBERON:0005181 ! thoracic segment organ
intersection_of: UBERON:0000211 ! ligament
intersection_of: part_of UBERON:0001103 ! diaphragm
relationship: part_of UBERON:0001103 ! diaphragm

[Term]
id: UBERON:0015228
name: circulatory organ
namespace: uberon
def: "A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile." [http://orcid.org/0000-0002-6601-2165]
subset: grouping_class
synonym: "cardiac pump" EXACT []
synonym: "cardiac structure" RELATED []
synonym: "circulatory vessel" NARROW []
synonym: "heart" BROAD []
synonym: "heart or heart like organ" EXACT []
xref: SPD:0000130
is_a: UBERON:0003103 ! compound organ
relationship: has_quality PATO:0001690 ! contractile
relationship: part_of UBERON:0001009 ! circulatory system

[Term]
id: UBERON:0015280
name: pancreas left lobe
namespace: uberon
def: "A pancreatic lobule that is in_the_left_side_of a exocrine pancreas." [OBOL:automatic]
xref: EMAPA:37711 {source="MA:th"}
xref: MA:0000722
is_a: UBERON:0007324 ! pancreatic lobule
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0007324 ! pancreatic lobule
intersection_of: in_left_side_of UBERON:0000017 ! exocrine pancreas
relationship: in_left_side_of UBERON:0000017 ! exocrine pancreas

[Term]
id: UBERON:0015281
name: pancreas right lobe
namespace: uberon
def: "A pancreatic lobule that is in_the_right_side_of a exocrine pancreas." [OBOL:automatic]
xref: EMAPA:37712 {source="MA:th"}
xref: MA:0000723
is_a: UBERON:0007324 ! pancreatic lobule
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0007324 ! pancreatic lobule
intersection_of: in_right_side_of UBERON:0000017 ! exocrine pancreas
relationship: in_right_side_of UBERON:0000017 ! exocrine pancreas

[Term]
id: UBERON:0015329
name: respiratory system basement membrane
namespace: uberon
def: "A basement membrane of epithelium that is part of a respiratory system." [OBOL:automatic]
xref: EMAPA:37570 {source="MA:th"}
xref: MA:0001815
is_a: UBERON:0005769 ! basement membrane of epithelium
intersection_of: UBERON:0005769 ! basement membrane of epithelium
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0003570 {source="MA"} ! respiratory system connective tissue

[Term]
id: UBERON:0015410
name: heart plus pericardium
namespace: uberon
subset: human_reference_atlas
synonym: "heart/pericardium" EXACT [MA:0002449]
xref: EMAPA:37597 {source="MA:th"}
xref: MA:0002449
is_a: UBERON:0005178 {source="MA"} ! thoracic cavity element
relationship: part_of UBERON:0004535 ! cardiovascular system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0015418
name: urethra mesenchymal layer
namespace: uberon
def: "A mesenchyme that is part of a urethra." [OBOL:automatic]
xref: EMAPA:37786 {source="MA:th"}
xref: MA:0002648
is_a: UBERON:0003104 ! mesenchyme
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0000057 ! urethra
relationship: part_of UBERON:0000057 ! urethra

[Term]
id: UBERON:0015420
name: ureteral valve
namespace: uberon
def: "A valve that is part of a ureter." [OBOL:automatic]
synonym: "ureteral valve" EXACT [MA:0002658]
synonym: "valve or ureter" EXACT []
xref: EMAPA:37781 {source="MA:th"}
xref: MA:0002658
is_a: UBERON:0003978 ! valve
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0003978 ! valve
intersection_of: part_of UBERON:0000056 ! ureter
relationship: capable_of GO:0035809 ! regulation of urine volume
relationship: part_of UBERON:0000056 ! ureter

[Term]
id: UBERON:0015480
name: proper hepatic artery
namespace: uberon
def: "The hepatic artery proper (also proper hepatic artery), arises from the common hepatic artery and runs alongside the portal vein and the common bile duct to form the portal triad. The hepatic artery proper gives off a small supraduodenal artery to the duodenal bulb. Then the right gastric artery comes off and runs to the left along the lesser curvature of the stomach to meet the left gastric artery, which is a branch of the celiac trunk. It subsequently gives off the cystic artery, which feeds the gallbladder, before bifurcating into the right and left hepatic arteries. Of note, the right and left hepatic arteries may demonstrate variant anatomy. A replaced right hepatic artery may arise from the superior mesenteric artery (SMA) and a replaced left hepatic artery may arise from the left gastric artery." [Wikipedia:Hepatic_artery_proper]
subset: human_reference_atlas
synonym: "hepatic artery proper" EXACT [FMA:14772]
synonym: "proper hepatic" RELATED [Wikipedia:Hepatic_artery_proper]
xref: EMAPA:37217 {source="MA:th"}
xref: FMA:14772
xref: MA:0003095
xref: SCTID:244262006
xref: Wikipedia:Hepatic_artery_proper
is_a: UBERON:0001193 {source="MA"} ! hepatic artery
relationship: connecting_branch_of UBERON:0005436 {source="FMA"} ! common hepatic artery
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0015481
name: left hepatic artery
namespace: uberon
def: "A hepatic artery that is part of a left lobe of liver." [OBOL:automatic]
subset: human_reference_atlas
synonym: "left branch of hepatic artery" EXACT [FMA:14779]
synonym: "left part of hepatic artery proper" EXACT [FMA:14779]
synonym: "ramus sinister (arteria hepatica propria)" EXACT OMO:0003011 [FMA:14779, FMA:TA]
xref: EMAPA:37096 {source="MA:th"}
xref: FMA:14779
xref: MA:0003096
is_a: UBERON:0001193 ! hepatic artery
is_a: UBERON:0015796 ! liver blood vessel
intersection_of: UBERON:0001193 ! hepatic artery
intersection_of: part_of UBERON:0001115 ! left lobe of liver
relationship: connected_to UBERON:0015480 ! proper hepatic artery
relationship: part_of UBERON:0001115 {source="FMA"} ! left lobe of liver
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0015482
name: right hepatic artery
namespace: uberon
def: "A hepatic artery that is part of a right lobe of liver." [OBOL:automatic]
subset: human_reference_atlas
synonym: "ramus dexter (arteria hepatica propria)" EXACT OMO:0003011 [FMA:14778, FMA:TA]
synonym: "right branch of hepatic artery proper" EXACT [FMA:14778]
synonym: "right part of hepatic artery proper" EXACT [FMA:14778]
xref: EMAPA:37376 {source="MA:th"}
xref: FMA:14778
xref: MA:0003097
is_a: UBERON:0001193 ! hepatic artery
is_a: UBERON:0015796 ! liver blood vessel
intersection_of: UBERON:0001193 ! hepatic artery
intersection_of: part_of UBERON:0001114 ! right lobe of liver
relationship: connected_to UBERON:0015480 ! proper hepatic artery
relationship: part_of UBERON:0001114 {source="FMA"} ! right lobe of liver
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0015485
name: choledocho-duodenal junction
namespace: uberon
def: "Hat part of the duodenal wall traversed by the ductus choledochus, ductus pancreaticus, and ampulla." [http://medical-dictionary.thefreedictionary.com/choledochoduodenal+junction]
synonym: "choledochoduodenal junction" EXACT [MA:0003108]
xref: EMAPA:37478 {source="MA:th"}
xref: MA:0003108
is_a: UBERON:1100000 ! digestive tract junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0002114 ! duodenum
intersection_of: connects UBERON:0002394 ! bile duct
relationship: connects UBERON:0002114 ! duodenum
relationship: connects UBERON:0002394 ! bile duct

[Term]
id: UBERON:0015716
name: anal canal epithelium
namespace: uberon
def: "An epithelium that is part of a anal canal." [OBOL:automatic]
subset: human_reference_atlas
synonym: "anal canal epithelium" EXACT [FMA:17511]
synonym: "epithelium of anal canal" EXACT [FMA:17511]
xref: EMAPA:18835
xref: FMA:17511
is_a: UBERON:0001278 ! epithelium of large intestine
is_a: UBERON:0014703 ! anal membrane ectodermal component
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000159 ! anal canal
relationship: part_of UBERON:0000159 ! anal canal
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0015717
name: smooth muscle tissue layer of ejaculatory duct
namespace: uberon
def: "A smooth muscle tissue that is part of a ejaculatory duct." [OBOL:automatic]
synonym: "muscle layer of ejaculatory duct" EXACT [FMA:19372]
xref: EMAPA:32289
xref: FMA:19372
is_a: UBERON:0001135 ! smooth muscle tissue
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0000999 ! ejaculatory duct
relationship: part_of UBERON:0000999 ! ejaculatory duct

[Term]
id: UBERON:0015757
name: heterogeneous tissue
namespace: uberon
synonym: "portion of heterogeneous tissue" EXACT [FMA:62798]
xref: FMA:62798
is_a: UBERON:0000479 {source="FMA"} ! tissue

[Term]
id: UBERON:0015783
name: smooth muscle layer in fatty layer of subcutaneous tissue
namespace: uberon
def: "A smooth muscle tissue that is part of a hypodermis." [OBOL:automatic]
synonym: "muscle layer in fatty layer of subcutaneous tissue" EXACT [FMA:77862]
synonym: "stratum musculosum panniculi adiposi telae subcutaneae" EXACT OMO:0003011 [FMA:77862, FMA:TA]
xref: FMA:77862
is_a: UBERON:0001135 ! smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0002072 ! hypodermis
relationship: part_of UBERON:0002072 ! hypodermis

[Term]
id: UBERON:0015796
name: liver blood vessel
namespace: uberon
def: "A blood vessel that is part of a liver." [OBOL:automatic]
synonym: "hepatic blood vessel" RELATED [EMAPA:35498]
xref: EMAPA:35498
xref: MA:0003137
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0003497 ! abdomen blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0002107 ! liver
relationship: part_of UBERON:0002107 ! liver

[Term]
id: UBERON:0015808
name: eye epithelium
namespace: uberon
def: "An epithelium that is part of a camera-type eye." [OBOL:automatic]
xref: EMAPA:35957
xref: MA:0003162
is_a: UBERON:0007625 ! pigment epithelium of eye
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000019 ! camera-type eye
relationship: part_of UBERON:0000019 ! camera-type eye

[Term]
id: UBERON:0015833
name: foregut epithelium
namespace: uberon
def: "An epithelium that is part of a foregut." [OBOL:automatic]
xref: EMAPA:32922
xref: MA:0003204
is_a: UBERON:0003929 ! digestive tract epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001041 ! foregut
relationship: part_of UBERON:0001041 ! foregut

[Term]
id: UBERON:0015834
name: duodenum lamina propria
namespace: uberon
def: "A lamina propria that is part of a duodenum." [OBOL:automatic]
subset: human_reference_atlas
synonym: "duodenal lamina propria" EXACT [FMA:15972]
synonym: "lamina propria mucosae of duodenum" EXACT [FMA:15972]
synonym: "lamina propria of duodenum" EXACT [FMA:15972]
xref: EMAPA:27255
xref: FMA:15972
xref: MA:0003209
is_a: UBERON:0001238 ! lamina propria of small intestine
intersection_of: UBERON:0000030 ! lamina propria
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: part_of UBERON:0008342 {source="FMA"} ! intestinal villus of duodenum
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0016405
name: pulmonary capillary
namespace: uberon
def: "A capillary that is part of a lung." [OBOL:automatic]
subset: human_reference_atlas
subset: pheno_slim
synonym: "capillary of lung" EXACT [FMA:14121]
xref: FMA:14121
is_a: UBERON:0003512 ! lung blood vessel
is_a: UBERON:0003526 ! respiratory system capillary
intersection_of: UBERON:0001982 ! capillary
intersection_of: part_of UBERON:0002048 ! lung
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0016458
name: esophageal hiatus
namespace: uberon
def: "A hole in the diaphragm through which the esophagus passes." [HP:0002036]
subset: pheno_slim
synonym: "esophageal hiatus of diaphragm" EXACT [FMA:58289]
synonym: "oesophageal aperture" EXACT [FMA:58289]
synonym: "oesophageal hiatus" EXACT [FMA:58289]
xref: FMA:58289
is_a: UBERON:0000161 ! orifice
intersection_of: UBERON:0000161 ! orifice
intersection_of: conduit_for UBERON:0001043 ! esophagus
intersection_of: part_of UBERON:0001103 ! diaphragm
relationship: conduit_for UBERON:0001043 ! esophagus
relationship: part_of UBERON:0001103 ! diaphragm

[Term]
id: UBERON:0016478
name: liver stroma
namespace: uberon
def: "A stroma that is part of a liver." [OBOL:automatic]
subset: human_reference_atlas
synonym: "hepatic stroma" EXACT [FMA:17553]
synonym: "stroma of liver" EXACT [FMA:17553]
xref: FMA:17553
is_a: UBERON:0003891 ! stroma
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0003891 ! stroma
intersection_of: part_of UBERON:0002107 ! liver
relationship: part_of UBERON:0002107 ! liver
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0016490
name: auditory system
namespace: uberon
def: "Is the sensory system for the sense of hearing." [NLXANAT:090817]
xref: EMAPA:36002
xref: FMA:7192
xref: MA:0002443
xref: NCIT:C12889
xref: neuronames:2888
xref: NLXANAT:090817
xref: UMLS:C0587901 {source="ncithesaurus:Auditory_System"}
xref: Wikipedia:Auditory_system
is_a: UBERON:0007037 ! mechanosensory system
intersection_of: UBERON:0001032 ! sensory system
intersection_of: capable_of GO:0007605 ! sensory perception of sound
relationship: capable_of GO:0007605 ! sensory perception of sound
relationship: part_of UBERON:0002105 ! vestibulo-auditory system
property_value: UBPROP:0000012 "Auditory system is general anatomical term in FMA" xsd:string {external_ontology="FMA"}

[Term]
id: UBERON:0016509
name: cavity of right ventricle
namespace: uberon
def: "Luminal space of the right ventricle of the heart." [http://orcid.org/0000-0002-6601-2165]
synonym: "right ventricle lumen" EXACT [EMAPA:26047]
synonym: "right ventricular cavity" EXACT [FMA:FMA]
xref: EMAPA:26047
xref: FMA:9291
is_a: UBERON:0035763 ! cavity of cardiac chamber
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0002080 ! heart right ventricle
relationship: luminal_space_of UBERON:0002080 ! heart right ventricle
relationship: part_of UBERON:0002080 ! heart right ventricle

[Term]
id: UBERON:0016510
name: epithelium of male urethra
namespace: uberon
def: "An epithelium that is part of a male urethra." [OBOL:automatic]
synonym: "male urethral epithelium" EXACT [FMA:FMA]
synonym: "urethral epithelium of male" EXACT [EMAPA:30467]
xref: EMAPA:30467
xref: FMA:19684
is_a: UBERON:0002325 ! epithelium of urethra
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001333 ! male urethra
relationship: part_of UBERON:0001333 ! male urethra

[Term]
id: UBERON:0016512
name: lumen of duodenum
namespace: uberon
def: "An anatomical space that is part of a duodenum." [OBOL:automatic]
synonym: "doudenal lumen" EXACT [FMA:FMA]
synonym: "duodenal lumen" EXACT [FMA:FMA]
xref: EMAPA:19080
xref: FMA:14589
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: part_of UBERON:0002114 ! duodenum
relationship: part_of UBERON:0002114 ! duodenum

[Term]
id: UBERON:0016513
name: cavity of left atrium
namespace: uberon
def: "Luminal space of the left atrium of the heart." [http://orcid.org/0000-0002-6601-2165]
synonym: "left atrial cavity" EXACT [FMA:FMA]
synonym: "left atrium lumen" EXACT [EMAPA:26011]
xref: EMAPA:26011
xref: FMA:9465
is_a: UBERON:0035763 ! cavity of cardiac chamber
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0002079 ! left cardiac atrium
relationship: luminal_space_of UBERON:0002079 ! left cardiac atrium
relationship: part_of UBERON:0002079 ! left cardiac atrium

[Term]
id: UBERON:0016514
name: cavity of left ventricle
namespace: uberon
def: "Luminal space of the left ventricle of the heart." [http://orcid.org/0000-0002-6601-2165]
synonym: "left ventricular cavity" EXACT [FMA:FMA]
xref: EMAPA:26038
xref: FMA:9466
is_a: UBERON:0035763 ! cavity of cardiac chamber
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0002084 ! heart left ventricle
relationship: luminal_space_of UBERON:0002084 ! heart left ventricle
relationship: part_of UBERON:0002084 ! heart left ventricle

[Term]
id: UBERON:0016520
name: epithelium of female urethra
namespace: uberon
def: "An epithelium that is part of a female urethra." [OBOL:automatic]
synonym: "female urethral epithelium" EXACT [FMA:FMA]
synonym: "urethral epithelium of female" EXACT [EMAPA:30470]
xref: EMAPA:30470
xref: FMA:19774
is_a: UBERON:0002325 ! epithelium of urethra
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0001334 ! female urethra
relationship: part_of UBERON:0001334 ! female urethra

[Term]
id: UBERON:0016522
name: cavity of right atrium
namespace: uberon
def: "Luminal space of the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165]
synonym: "right atrial cavity" EXACT [FMA:FMA]
xref: EMAPA:26020
xref: FMA:11359
is_a: UBERON:0035763 ! cavity of cardiac chamber
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0002078 ! right cardiac atrium
relationship: luminal_space_of UBERON:0002078 ! right cardiac atrium
relationship: part_of UBERON:0002078 ! right cardiac atrium

[Term]
id: UBERON:0016545
name: pharyngeal ectoderm
namespace: uberon
alt_id: UBERON:2001379
def: "The external part of the developing pharynx that is made of ectoderm. During vertebrate development, pockets form in pharyngeal ectoderm between the pharyngeal arches." [http://orcid.org/0000-0002-6601-2165, PMID:23020903]
xref: TAO:0001379
xref: ZFA:0001379
is_a: UBERON:0000490 ! unilaminar epithelium
is_a: UBERON:0003351 ! pharyngeal epithelium
is_a: UBERON:0005291 ! embryonic tissue
intersection_of: UBERON:0000490 ! unilaminar epithelium
intersection_of: part_of UBERON:0000076 ! external ectoderm
intersection_of: part_of UBERON:0001042 ! chordate pharynx
relationship: part_of UBERON:0000076 ! external ectoderm

[Term]
id: UBERON:0016548
name: central nervous system gray matter layer
namespace: uberon
def: "A layer of of the central nervous system that is part of gray matter." [http://orcid.org/0000-0002-6601-2165]
synonym: "CNS gray matter layer" EXACT []
synonym: "CNS grey matter layer" EXACT []
synonym: "gray matter layer of neuraxis" EXACT [FMA:83142]
synonym: "grey matter layer" BROAD []
synonym: "grey matter layer of neuraxis" EXACT []
xref: FMA:83142
is_a: UBERON:0022303 ! nervous system cell part layer
intersection_of: UBERON:0022303 ! nervous system cell part layer
intersection_of: composed_primarily_of UBERON:0002020 ! gray matter
relationship: composed_primarily_of UBERON:0002020 ! gray matter

[Term]
id: UBERON:0016550
name: spinal cord column
namespace: uberon
is_a: UBERON:0011215 ! central nervous system cell part cluster
relationship: part_of UBERON:0002240 ! spinal cord

[Term]
id: UBERON:0016552
name: phlegm
namespace: uberon
def: "Mucus produced in the respiratory tract." [http://orcid.org/0000-0002-6601-2165]
xref: NCIT:C93171
xref: UMLS:C0225378
is_a: UBERON:0000912 ! mucus
intersection_of: UBERON:0000912 ! mucus
intersection_of: produced_by UBERON:0000065 ! respiratory tract
relationship: produced_by UBERON:0000065 ! respiratory tract

[Term]
id: UBERON:0016553
name: respiratory system mucus
namespace: uberon
def: "Any mucus produced by a mucosae of the respiratory system. This includes the mucus produced in the nasal cavity (nasal mucus) and mucus produced in the respiratory tract (phlegm)." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Nasal_mucus#Respiratory_system]
is_a: UBERON:0000912 ! mucus
intersection_of: UBERON:0000912 ! mucus
intersection_of: produced_by UBERON:0004785 ! respiratory system mucosa
relationship: produced_by UBERON:0004785 ! respiratory system mucosa

[Term]
id: UBERON:0016566
name: pit
namespace: uberon
def: "An roughly circular indentation in a surface." [AEO:0000204, AEO:JB]
subset: upper_level
xref: AEO:0000204
is_a: UBERON:0036215 ! anatomical surface region

[Term]
id: UBERON:0016570
name: lamina of gray matter of spinal cord
namespace: uberon
synonym: "rexed lamina" EXACT [FMA:68861]
xref: FMA:68861
xref: http://neurolex.org/wiki/Category\:Rexed_spinal_cord_parcellation_scheme_region
xref: Wikipedia:Rexed_laminae
is_a: UBERON:0011215 ! central nervous system cell part cluster
is_a: UBERON:0022303 ! nervous system cell part layer
intersection_of: UBERON:0022303 ! nervous system cell part layer
intersection_of: part_of UBERON:0002315 ! gray matter of spinal cord
relationship: part_of UBERON:0002315 ! gray matter of spinal cord

[Term]
id: UBERON:0016854
name: dorsal part of optic cup
namespace: uberon
def: "The dorsal region of the optic cup that gives rise to the dorsal part of the retina." [http://orcid.org/0000-0002-6601-2165]
synonym: "dorsal optic cup" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "dorsal region of optic cup" EXACT [http://orcid.org/0000-0002-6601-2165]
is_a: UBERON:0000481 ! multi-tissue structure
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000481 ! multi-tissue structure
intersection_of: in_dorsal_side_of UBERON:0003072 ! optic cup
relationship: in_dorsal_side_of UBERON:0003072 ! optic cup
relationship: part_of UBERON:0003072 ! optic cup

[Term]
id: UBERON:0016879
name: future central nervous system
namespace: uberon
alt_id: UBERON:3000469
def: "Primordium that develops into the central nervous system." [http://orcid.org/0000-0002-6601-2165]
synonym: "future CNS" EXACT []
synonym: "presumptive central nervous system" EXACT []
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0001017 ! central nervous system
relationship: develops_from UBERON:0000924 ! ectoderm
relationship: develops_from UBERON:0002346 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! neurectoderm
relationship: has_potential_to_develop_into UBERON:0001017 ! central nervous system
relationship: part_of UBERON:0016880 ! future nervous system

[Term]
id: UBERON:0016880
name: future nervous system
namespace: uberon
alt_id: UBERON:3000477
def: "Primordium that develops into the nervous system." [http://orcid.org/0000-0002-6601-2165]
synonym: "presumptive nervous system" EXACT [AAO:0000477]
xref: AAO:0000477
is_a: UBERON:0006598 ! presumptive structure
intersection_of: UBERON:0006598 ! presumptive structure
intersection_of: has_potential_to_develop_into UBERON:0001016 ! nervous system
relationship: existence_starts_during_or_after UBERON:0000111 ! organogenesis stage
relationship: has_potential_to_develop_into UBERON:0001016 ! nervous system

[Term]
id: UBERON:0016885
name: epithelium of terminal part of digestive tract
namespace: uberon
def: "Epithelium lining the distalmost portion of the digestive tract." [http://orcid.org/0000-0002-6601-2165]
synonym: "rectum epithelium" NARROW [BTO:0005445]
xref: BTO:0005445
xref: WBbt:0005800
is_a: UBERON:0003929 ! digestive tract epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0006866 ! terminal part of digestive tract
relationship: part_of UBERON:0006866 ! terminal part of digestive tract

[Term]
id: UBERON:0016886
name: muscle tissue of terminal part of digestive tract
namespace: uberon
def: "Any muscle tissue of the distalmost portion of the digestive tract." [http://orcid.org/0000-0002-6601-2165]
synonym: "rectum muscle" NARROW []
synonym: "rectum muscle structure" NARROW []
is_a: UBERON:0002385 ! muscle tissue
intersection_of: UBERON:0002385 ! muscle tissue
intersection_of: part_of UBERON:0006866 ! terminal part of digestive tract
relationship: part_of UBERON:0006866 ! terminal part of digestive tract

[Term]
id: UBERON:0016887
name: entire extraembryonic component
namespace: uberon
def: "The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism." [AEO:0000195, AEO:JB]
synonym: "extra-embryonic component" EXACT []
synonym: "extraembryonic component" EXACT [AEO:0000195]
xref: AEO:0000195
xref: EHDAA2:0000003
xref: EMAPA:16042
is_a: UBERON:0000481 {source="AEO"} ! multi-tissue structure
relationship: adjacent_to UBERON:0002050 ! embryonic structure
relationship: existence_starts_and_ends_during UBERON:0000068 ! embryo stage
relationship: part_of UBERON:0004716 {source="AEO"} ! conceptus

[Term]
id: UBERON:0016888
name: transitional anatomical structure
namespace: uberon
def: "An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development." [AEO:0000132, AEO:JB]
xref: AEO:0000132
is_a: UBERON:0005423 {source="AEO"} ! developing anatomical structure

[Term]
id: UBERON:0017650
name: developing mesenchymal structure
namespace: uberon
def: "A mesenchyme-derived anatomical entity undergoing a transtion to become another structure." [AEO:0001016, AEO:JB]
xref: AEO:0001016
is_a: UBERON:0005423 ! developing anatomical structure
intersection_of: UBERON:0005423 ! developing anatomical structure
intersection_of: composed_primarily_of UBERON:0003104 ! mesenchyme
relationship: composed_primarily_of UBERON:0003104 ! mesenchyme

[Term]
id: UBERON:0017672
name: abdominal viscera
namespace: uberon
def: "A viscus that is part of a abdomen." [OBOL:automatic]
subset: pheno_slim
synonym: "abdominal viscera" EXACT [FMA:32413]
synonym: "abdominal viscera set" EXACT [FMA:32413]
synonym: "set of abdominal viscera" EXACT [FMA:32413]
xref: FMA:32413
xref: FMA:67355
is_a: UBERON:0002075 ! viscus
is_a: UBERON:0005172 ! abdomen element
intersection_of: UBERON:0002075 ! viscus
intersection_of: part_of UBERON:0000916 ! abdomen

[Term]
id: UBERON:0018111
name: muscle layer of rectum
namespace: uberon
def: "A muscle layer that is part of the rectum." [http://orcid.org/0000-0002-6601-2165]
synonym: "muscular coat of rectum" EXACT [FMA:15035]
synonym: "muscularis externa of rectum" EXACT [FMA:15035]
synonym: "rectal muscularis propria" EXACT [FMA:15035]
synonym: "tunica muscularis (rectum)" EXACT [FMA:15035]
synonym: "tunica muscularis recti" EXACT [FMA:TA]
xref: FMA:15035
is_a: UBERON:0011198 ! muscle layer of large intestine
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0001052 ! rectum
relationship: part_of UBERON:0001052 ! rectum

[Term]
id: UBERON:0018112
name: rectum smooth muscle tissue
namespace: uberon
def: "Any portion of smooth muscle tissue that is part of the rectum." [http://orcid.org/0000-0002-6601-2165]
synonym: "rectal smooth muscle tissue" EXACT []
synonym: "rectum smooth muscle" EXACT []
synonym: "smooth muscle of rectum" EXACT []
is_a: UBERON:0004220 ! large intestine smooth muscle
is_a: UBERON:0004231 ! anal region smooth muscle
is_a: UBERON:0016886 ! muscle tissue of terminal part of digestive tract
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001052 ! rectum
relationship: part_of UBERON:0001052 ! rectum

[Term]
id: UBERON:0018113
name: left kidney interstitium
namespace: uberon
def: "A kidney interstitium that is part of a left kidney." [OBOL:automatic]
synonym: "left renal stroma" EXACT [FMA:74271]
synonym: "stroma of left kidney" EXACT [FMA:74271]
xref: FMA:74271
is_a: UBERON:0005215 ! kidney interstitium
intersection_of: UBERON:0005215 ! kidney interstitium
intersection_of: part_of UBERON:0004538 ! left kidney
relationship: part_of UBERON:0004538 ! left kidney

[Term]
id: UBERON:0018114
name: right kidney interstitium
namespace: uberon
def: "A kidney interstitium that is part of a right kidney." [OBOL:automatic]
synonym: "right renal stroma" EXACT [FMA:74270]
synonym: "stroma of right kidney" EXACT [FMA:74270]
xref: FMA:74270
is_a: UBERON:0005215 ! kidney interstitium
intersection_of: UBERON:0005215 ! kidney interstitium
intersection_of: part_of UBERON:0004539 ! right kidney
relationship: part_of UBERON:0004539 ! right kidney

[Term]
id: UBERON:0018115
name: left renal pelvis
namespace: uberon
def: "A renal pelvis that is part of a left ureter." [OBOL:automatic]
synonym: "pelvis of left ureter" EXACT [FMA:15579]
synonym: "renal pelvis of left kidney" EXACT [FMA:15579]
xref: FMA:15579
xref: SCTID:243436005
is_a: UBERON:0001224 ! renal pelvis
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0001224 ! renal pelvis
intersection_of: part_of UBERON:0001223 ! left ureter
relationship: part_of UBERON:0001223 ! left ureter

[Term]
id: UBERON:0018116
name: right renal pelvis
namespace: uberon
def: "A renal pelvis that is part of a right ureter." [OBOL:automatic]
synonym: "pelvis of right kidney" EXACT [FMA:15578]
synonym: "pelvis of right ureter" EXACT [FMA:15578]
xref: FMA:15578
xref: SCTID:243419002
is_a: UBERON:0001224 ! renal pelvis
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0001224 ! renal pelvis
intersection_of: part_of UBERON:0001222 ! right ureter
relationship: part_of UBERON:0001222 ! right ureter

[Term]
id: UBERON:0018117
name: left renal cortex interstitium
namespace: uberon
def: "A renal cortex interstitium that is part of a left kidney." [OBOL:automatic]
synonym: "cortical interstitial tissue of left kidney" EXACT []
is_a: UBERON:0005270 ! renal cortex interstitium
is_a: UBERON:0018113 ! left kidney interstitium
intersection_of: UBERON:0005270 ! renal cortex interstitium
intersection_of: part_of UBERON:0004538 ! left kidney

[Term]
id: UBERON:0018118
name: right renal cortex interstitium
namespace: uberon
def: "A renal cortex interstitium that is part of a right kidney." [OBOL:automatic]
synonym: "cortical interstitial tissue of right kidney" EXACT []
is_a: UBERON:0005270 ! renal cortex interstitium
is_a: UBERON:0018114 ! right kidney interstitium
intersection_of: UBERON:0005270 ! renal cortex interstitium
intersection_of: part_of UBERON:0004539 ! right kidney

[Term]
id: UBERON:0018135
name: fibrocollagenous connective tissue
namespace: uberon
xref: FMA:83521
is_a: UBERON:0011824 ! fibrous connective tissue
intersection_of: UBERON:0011824 ! fibrous connective tissue
intersection_of: has_quality PATO:0002462 ! collagenous
relationship: has_quality PATO:0002462 ! collagenous

[Term]
id: UBERON:0018142
name: caudal vertebra endochondral element
namespace: uberon
alt_id: UBERON:0015006
def: "Any vertebra endochondral element that is part of the caudal region of the vertebral column (tail or coccyx)." [http://orcid.org/0000-0002-6601-2165]
synonym: "caudal vertebra element" EXACT []
synonym: "coccygeal vertebra element" NARROW []
synonym: "coccyx vertebra element" NARROW []
synonym: "tail vertebra element" EXACT []
is_a: UBERON:0005174 ! dorsal region element
is_a: UBERON:0010913 ! vertebral element
intersection_of: UBERON:0010913 ! vertebral element
intersection_of: part_of UBERON:0006076 ! caudal region of vertebral column
union_of: UBERON:0001095 ! caudal vertebra
union_of: UBERON:0013503 ! caudal vertebra cartilage element
union_of: UBERON:0013504 ! caudal vertebra pre-cartilage condensation
relationship: part_of UBERON:0006076 ! caudal region of vertebral column

[Term]
id: UBERON:0018150
name: skin of lower lip
namespace: uberon
def: "A zone of skin that is part of a lower lip." [OBOL:automatic]
synonym: "lower lip skin" EXACT [FMA:24767]
xref: FMA:24767
xref: SCTID:281630002
is_a: UBERON:0001458 ! skin of lip
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0001835 ! lower lip
relationship: part_of UBERON:0001835 ! lower lip

[Term]
id: UBERON:0018151
name: skin of upper lip
namespace: uberon
def: "A zone of skin that is part of a upper lip." [OBOL:automatic]
synonym: "upper lip skin" EXACT [FMA:24765]
xref: FMA:24765
xref: SCTID:281629007
is_a: UBERON:0001458 ! skin of lip
is_a: UBERON:1000021 ! skin of face
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0001834 ! upper lip
relationship: part_of UBERON:0001834 ! upper lip

[Term]
id: UBERON:0018234
name: stroma of pancreas
namespace: uberon
def: "A stroma that is part of a pancreas." [OBOL:automatic]
subset: human_reference_atlas
synonym: "pancreatic stroma" EXACT [FMA:63121]
xref: FMA:63121
is_a: UBERON:0003891 ! stroma
intersection_of: UBERON:0003891 ! stroma
intersection_of: part_of UBERON:0001264 ! pancreas
relationship: part_of UBERON:0001264 ! pancreas
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0018239
name: rhombomere boundary
namespace: uberon
def: "A boundary delimiting a rhombomere." [GO:0021654]
synonym: "rhombomere junction" EXACT []
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0007651 ! anatomical junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0001892 ! rhombomere
relationship: connects UBERON:0001892 ! rhombomere
relationship: part_of UBERON:0007277 ! presumptive hindbrain

[Term]
id: UBERON:0018252
name: internal pudendal vein
namespace: uberon
def: "Accompanying vein of internal pudendal artery." [Wikipedia:Internal_pudendal_veins]
subset: human_reference_atlas
synonym: "internal pudic vein" RELATED [Wikipedia:Internal_pudendal_veins]
synonym: "vena pudenda interna" EXACT OMO:0003011 [Wikipedia:Internal_pudendal_veins]
xref: FMA:18917
xref: SCTID:14885008
xref: Wikipedia:Internal_pudendal_veins
is_a: UBERON:0009029 ! pudendal vein
relationship: connected_to UBERON:0001317 ! internal iliac vein
relationship: part_of RO:0002577 ! system
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000008 "In humans, they begin in the deep veins of the penis which issue from the corpus cavernosum penis, accompany the internal pudendal artery, and unite to form a single vessel, which ends in the internal iliac vein. They receive the veins from the urethral bulb, and the perineal and inferior hemorrhoidal veins" xsd:string

[Term]
id: UBERON:0018254
name: skeletal musculature
namespace: uberon
subset: grouping_class
subset: human_reference_atlas
xref: EHDAA2:0001842
xref: EMAPA:35578
xref: MA:0000165
is_a: UBERON:0000061 ! anatomical structure
relationship: composed_primarily_of UBERON:0014892 ! skeletal muscle organ, vertebrate
relationship: part_of UBERON:0000383 {source="MA"} ! musculature of body
property_value: editor_note "Added for consistency with MA EMAPA and EHDAA2. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/104" xsd:string
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0018257
name: submucosa of digestive tract
namespace: uberon
def: "Any portion of submucosa that lines the digestive tract." [http://orcid.org/0000-0002-6601-2165]
is_a: UBERON:0000009 ! submucosa
intersection_of: UBERON:0000009 ! submucosa
intersection_of: part_of UBERON:0001555 ! digestive tract
relationship: part_of UBERON:0001555 ! digestive tract

[Term]
id: UBERON:0018260
name: layer of muscle tissue
namespace: uberon
def: "Any organ component layer that consists of muscle tissue." [http://orcid.org/0000-0002-6601-2165]
xref: FMA:45634
xref: NCIT:C75444
xref: UMLS:C0225358
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: composed_primarily_of UBERON:0002385 ! muscle tissue
relationship: composed_primarily_of UBERON:0002385 ! muscle tissue
property_value: UBPROP:0000012 "NCITA class may refer to smooth muscle only" xsd:string {external_ontology="NCIT"}

[Term]
id: UBERON:0018261
name: muscular coat of digestive tract
namespace: uberon
def: "A muscular coat that is part of a digestive tract." [OBOL:automatic]
synonym: "muscular layer of digestive tract" RELATED []
synonym: "muscularis externa of digestive tract" RELATED []
synonym: "tunica externa of digestive tract" RELATED []
synonym: "tunica muscularis of digestive tract" EXACT []
is_a: UBERON:0006660 ! muscular coat
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0001555 ! digestive tract
relationship: capable_of_part_of GO:0030432 ! peristalsis
relationship: part_of UBERON:0001555 ! digestive tract
property_value: UBPROP:0000009 "responsible for gut movement, such as peristalsis" xsd:string

[Term]
id: UBERON:0018415
name: ethmoid foramen
namespace: uberon
def: "An bone foramen in the ethmoid bone." [http://orcid.org/0000-0002-6601-2165]
comment: Taxon nodes: In humans, refers to anterior or posterior ethmoid foramina
synonym: "ethmoid foramina" RELATED OMO:0003004 []
synonym: "ethmoidal foramen" EXACT []
synonym: "ethmoidal foramina" RELATED OMO:0003004 []
synonym: "foramina ethmoidalia" EXACT OMO:0003011 []
xref: Wikipedia:Ethmoidal_foramina
is_a: UBERON:0010313 ! neural crest-derived structure
is_a: UBERON:0013685 ! foramen of skull
intersection_of: UBERON:0004111 ! anatomical conduit
intersection_of: part_of UBERON:0001679 ! ethmoid bone
relationship: part_of UBERON:0001679 ! ethmoid bone
property_value: UBPROP:0000008 "There are usually two Foramina ethmoidalia present on each side in the dog. Sometimes one is situated rostral to the other, but often it is dorsal. They are not homologous with the Foramen ethmoidale anterius and Foramen ethmoidale posterius of man. Therefore they are not listed separately.[NOMINA ANATOMICA VETERINARIA (2005)]" xsd:string

[Term]
id: UBERON:0018543
name: lumen of intestine
namespace: uberon
def: "The anatomical space within the intestine." [http://orcid.org/0000-0002-6601-2165]
synonym: "gut lumen" RELATED [ZFA:0005807]
synonym: "intestinal lumen" EXACT [FMA:14586]
synonym: "intestine lumen" EXACT [ZFA:0005807]
xref: FMA:14586
xref: TADS:0000495
xref: WBbt:0005791
xref: ZFA:0005807
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0000160 ! intestine
relationship: luminal_space_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0000160 ! intestine
property_value: editor_note "see notes in inclusivity in class 'intestine'" xsd:string

[Term]
id: UBERON:0018544
name: trigeminal nerve muscle
namespace: uberon
def: "Muscle innervated by the trigeminal nerve (Cranial Nerve V)." [MFMO:0000072]
synonym: "muscle innervated by the trigeminal nerve" EXACT []
synonym: "muscles innervated by the trigeminal nerve" EXACT OMO:0003004 [MFMO:0000072]
xref: MFMO:0000072
is_a: UBERON:0001630 ! muscle organ
intersection_of: UBERON:0001630 ! muscle organ
intersection_of: innervated_by UBERON:0001645 ! trigeminal nerve
relationship: develops_from UBERON:0004362 ! pharyngeal arch 1
relationship: innervated_by UBERON:0001645 ! trigeminal nerve

[Term]
id: UBERON:0018649
name: cardiac muscle tissue of ventricle
namespace: uberon
synonym: "ventricular cardiac muscle tissue" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "ventricular heart muscle" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "ventricular muscle" RELATED [http://orcid.org/0000-0002-6601-2165]
xref: FMA:83450
is_a: UBERON:0004493 ! cardiac muscle tissue of myocardium
intersection_of: UBERON:0001133 ! cardiac muscle tissue
intersection_of: part_of UBERON:0002082 ! cardiac ventricle
relationship: part_of UBERON:0001083 ! myocardium of ventricle

[Term]
id: UBERON:0018674
name: heart vasculature
namespace: uberon
def: "An interconnected tubular multi-tissue structure that contains fluid that is actively transported around the heart." [ZFA:0005811, ZFA:CVS]
synonym: "cardiac vasculature" EXACT [FMA:73747]
xref: FMA:73747
xref: ZFA:0005811
is_a: UBERON:0002201 ! vasculature of trunk
is_a: UBERON:0006876 ! vasculature of organ
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0000948 ! heart
relationship: part_of UBERON:0000948 ! heart

[Term]
id: UBERON:0018692
name: dorsal side of post-anal tail
namespace: uberon
is_a: UBERON:0034929 ! external soft tissue zone
intersection_of: UBERON:0034929 ! external soft tissue zone
intersection_of: in_dorsal_side_of UBERON:0007812 ! post-anal tail
relationship: in_dorsal_side_of UBERON:0007812 ! post-anal tail
relationship: part_of UBERON:0001137 ! dorsum
relationship: part_of UBERON:0007812 ! post-anal tail

[Term]
id: UBERON:0018707
name: bladder organ
namespace: uberon
def: "A membranous sac in animals that serves as the receptacle of a liquid or contains gas." [BTO:0000123]
synonym: "bladder" NARROW [BTO:0000123]
xref: BTO:0000123
is_a: UBERON:0000489 ! cavitated compound organ
is_a: UBERON:0009856 ! sac
relationship: has_quality PATO:0002468 ! distensible
relationship: location_of UBERON:0000463 ! organism substance

[Term]
id: UBERON:0019042
name: reproductive system mucosa
namespace: uberon
synonym: "genital mucosa" EXACT [BTO:0002439]
xref: BTO:0002439
is_a: UBERON:0000344 ! mucosa
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0000990 ! reproductive system

[Term]
id: UBERON:0019143
name: intramuscular adipose tissue
namespace: uberon
def: "Adipose tissue which is located throughout skeletal muscle and is responsible for the marbling seen in certain cuts of beef. In humans, excess accumulation of intramuscular fat is associated with insulin resistance and type 2 diabetes." [BTO:0004043]
synonym: "intramuscular fat" RELATED [BTO:0004043]
xref: BTO:0004043
is_a: UBERON:0001013 ! adipose tissue
intersection_of: UBERON:0001013 ! adipose tissue
intersection_of: part_of UBERON:0014892 ! skeletal muscle organ, vertebrate
relationship: part_of UBERON:0014892 ! skeletal muscle organ, vertebrate

[Term]
id: UBERON:0019189
name: carotid artery endothelium
namespace: uberon
synonym: "carotid endothelium" RELATED [BTO:0004626]
synonym: "carotid epithelium" RELATED []
xref: BTO:0004626
is_a: UBERON:0001917 ! endothelium of artery
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0005396 ! carotid artery segment
relationship: part_of UBERON:0005396 ! carotid artery segment

[Term]
id: UBERON:0019190
name: mucous gland of lung
namespace: uberon
synonym: "bronchial gland" EXACT [FMA:13119]
synonym: "bronchial mucous gland" EXACT [FMA:13119]
synonym: "peribronchial gland" EXACT [BTO:0004638]
xref: BTO:0004638
xref: FMA:13119
xref: SCTID:88410004
is_a: UBERON:0000414 ! mucous gland
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0005181 ! thoracic segment organ
is_a: UBERON:0036225 ! respiratory system gland
intersection_of: UBERON:0000414 ! mucous gland
intersection_of: part_of UBERON:0002048 ! lung
relationship: part_of UBERON:0002048 ! lung

[Term]
id: UBERON:0019204
name: skin epithelium
namespace: uberon
def: "Any region of epithelium that is part of a skin region." [http://orcid.org/0000-0002-6601-2165]
xref: BTO:0004382
is_a: UBERON:0010371 ! ecto-epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000014 ! zone of skin
relationship: part_of UBERON:0000014 ! zone of skin

[Term]
id: UBERON:0019207
name: chorioretinal region
namespace: uberon
def: "The part of the eye that consists of both the retina and the optic choroid." [http://orcid.org/0000-0002-6601-2165, UBERON:drseb]
subset: pheno_slim
synonym: "chorioretina" EXACT []
synonym: "choroid and retina" EXACT []
synonym: "retinachoroid" EXACT []
synonym: "retinachoroidal region" EXACT []
xref: SCTID:110701000
is_a: UBERON:0000481 ! multi-tissue structure
is_a: UBERON:0004121 ! ectoderm-derived structure
is_a: UBERON:0010314 ! structure with developmental contribution from neural crest
relationship: has_part UBERON:0000966 ! retina
relationship: has_part UBERON:0001776 ! optic choroid
relationship: part_of NCBITaxon:6072 ! Eumetazoa
relationship: part_of UBERON:0010230 ! eyeball of camera-type eye

[Term]
id: UBERON:0019263
name: gray matter of hindbrain
namespace: uberon
subset: human_reference_atlas
synonym: "gray matter of the hindbrain" EXACT [DHBA:HGM]
xref: DHBA:10654
xref: FMA:268630
is_a: UBERON:0003528 ! brain gray matter
intersection_of: UBERON:0002020 ! gray matter
intersection_of: part_of UBERON:0002028 ! hindbrain
relationship: part_of UBERON:0002028 ! hindbrain
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0019267
name: gray matter of midbrain
namespace: uberon
subset: human_reference_atlas
xref: DHBA:10649
xref: FMA:83913
is_a: UBERON:0003528 ! brain gray matter
intersection_of: UBERON:0002020 ! gray matter
intersection_of: part_of UBERON:0001891 ! midbrain
relationship: part_of UBERON:0001891 ! midbrain
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0019304
name: sensory organ epithelium
namespace: uberon
xref: EMAPA:35952
xref: MA:0003174
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000020 ! sense organ
relationship: part_of UBERON:0000020 ! sense organ

[Term]
id: UBERON:0019319
name: exocrine gland of integumental system
namespace: uberon
def: "An exocrine gland that is part of a integumental system." [GOC:dos, http://orcid.org/0000-0002-6601-2165]
synonym: "integumental exocrine gland" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "integumental system exocrine gland" EXACT [http://orcid.org/0000-0002-6601-2165]
is_a: UBERON:0002365 ! exocrine gland
is_a: UBERON:0003297 ! gland of integumental system
intersection_of: UBERON:0002365 ! exocrine gland
intersection_of: part_of UBERON:0002416 ! integumental system

[Term]
id: UBERON:0022288
name: surface of eyeball
namespace: uberon
synonym: "surface of region of wall of eyeball" RELATED [FMA:58315]
xref: FMA:58315
is_a: UBERON:0036215 ! anatomical surface region
intersection_of: UBERON:0036215 ! anatomical surface region
intersection_of: bounding_layer_of UBERON:0010230 ! eyeball of camera-type eye
relationship: bounding_layer_of UBERON:0010230 ! eyeball of camera-type eye
relationship: part_of UBERON:0010230 ! eyeball of camera-type eye

[Term]
id: UBERON:0022292
name: splenic arteriole
namespace: uberon
xref: NCIT:C33596
xref: SCTID:282511007
is_a: UBERON:0001980 ! arteriole
is_a: UBERON:0003497 ! abdomen blood vessel
intersection_of: UBERON:0001980 ! arteriole
intersection_of: part_of UBERON:0002106 ! spleen
relationship: part_of UBERON:0002106 ! spleen

[Term]
id: UBERON:0022293
name: reproductive gland secretion
namespace: uberon
def: "A portion of organism substance that is secreted by a reproductive gland." [UBERON:cjm]
synonym: "genital fluid" RELATED []
synonym: "genital secretion" RELATED []
synonym: "reproductive system fluid" RELATED []
synonym: "reproductive system fluid/secretion" RELATED []
synonym: "reproductive system secretion" RELATED []
is_a: UBERON:0000463 ! organism substance
intersection_of: UBERON:0000463 ! organism substance
intersection_of: produced_by UBERON:0003937 ! reproductive gland
relationship: produced_by UBERON:0003937 ! reproductive gland

[Term]
id: UBERON:0022303
name: nervous system cell part layer
namespace: uberon
def: "Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]." [NLX:149357]
subset: cumbo
synonym: "lamina" BROAD [CUMBO:CUMBO]
synonym: "layer" BROAD [CUMBO:CUMBO]
xref: NLX:149357
is_a: UBERON:0005162 ! multi cell part structure
intersection_of: UBERON:0005162 ! multi cell part structure
intersection_of: has_quality PATO:0002124 ! laminar
intersection_of: part_of UBERON:0001016 ! nervous system
relationship: has_quality PATO:0002124 ! laminar
relationship: part_of UBERON:0001016 ! nervous system
property_value: editor_note "this is currently used to group some cellular layers that may not strictly conform to the CARO definition of cell-part layer. Consider genericisizing and introducing subtypes for cellular layer, fibrous layer and cell soma layer" xsd:string

[Term]
id: UBERON:0022350
name: visceral serous membrane
namespace: uberon
def: "Serous membrane layer that is adjacent to and lines an organ." [http://orcid.org/0000-0002-6601-2165]
synonym: "visceral wall of serous membrane" EXACT [FMA:15860]
xref: FMA:15860
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: adjacent_to UBERON:0000062 ! organ
intersection_of: part_of UBERON:0000042 ! serous membrane
relationship: adjacent_to UBERON:0000062 ! organ
relationship: part_of UBERON:0000042 ! serous membrane

[Term]
id: UBERON:0022351
name: parietal serous membrane
namespace: uberon
def: "Serous membrane layer that lines to a body cavity." [http://orcid.org/0000-0002-6601-2165]
synonym: "cavity lining" BROAD [MA:0002448]
synonym: "parietal wall of serous membrane" EXACT [FMA:15859]
xref: FMA:15859
xref: MA:0002448
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0004923 ! organ component layer
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: adjacent_to UBERON:0002553 ! anatomical cavity
intersection_of: part_of UBERON:0000042 ! serous membrane
relationship: adjacent_to UBERON:0002553 ! anatomical cavity
relationship: part_of UBERON:0000042 ! serous membrane

[Term]
id: UBERON:0022355
name: basal layer of endometrium
namespace: uberon
def: "The layer of endometrial epithelium adjacent to the uterine cavity." [Wikipedia:Endometrium#Histology]
subset: human_reference_atlas
synonym: "pars basalis of endometrium" EXACT []
synonym: "stratum basalis of endometrium" EXACT [FMA:86492]
xref: FMA:86492
xref: NCIT:C32189
is_a: UBERON:0004811 ! endometrium epithelium
intersection_of: UBERON:0004811 ! endometrium epithelium
intersection_of: adjacent_to UBERON:0013769 ! uterine lumen
relationship: adjacent_to UBERON:0013769 ! uterine lumen
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0022358
name: placenta blood vessel
namespace: uberon
def: "A blood vessel of the placenta." [GO:0060674]
subset: human_reference_atlas
synonym: "placental vessel" BROAD []
xref: SCTID:280716005
is_a: UBERON:0001981 ! blood vessel
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0001987 ! placenta
relationship: part_of UBERON:0001987 ! placenta
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0022361
name: lung field
namespace: uberon
def: "A specific region of the foregut into the area in which the lung will develop." [GOC:dph, GOC:mtg_lung]
synonym: "lung field" EXACT []
xref: SCTID:34922002
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0007688 ! anlage
intersection_of: UBERON:0007688 ! anlage
intersection_of: has_potential_to_develop_into UBERON:0002048 ! lung
relationship: has_potential_to_develop_into UBERON:0002048 ! lung
relationship: part_of UBERON:0003258 ! endoderm of foregut

[Term]
id: UBERON:0034705
name: developing neuroepithelium
namespace: uberon
def: "An embryonic or larval epithelium that is committed to form part of the nervous system." [AEO:0001008, AEO:JB]
synonym: "embryonic neuroepithelium" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "neurepithelium" BROAD [BTO:0000314]
synonym: "neuroepithelium" EXACT [AEO:0001008]
xref: AEO:0001008
xref: BTO:0000314
xref: EHDAA2_RETIRED:0004654
xref: FMA:64807
is_a: UBERON:0000483 ! epithelium
relationship: part_of UBERON:0001016 ! nervous system

[Term]
id: UBERON:0034706
name: proliferating neuroepithelium
namespace: uberon
def: "An epithelium that is undergoing proliferation to provide large numbers of neuronal cells." [AEO:0001009]
xref: AEO:0001009
is_a: UBERON:0034705 {source="AEO"} ! developing neuroepithelium

[Term]
id: UBERON:0034707
name: differentiating neuroepithelium
namespace: uberon
def: "A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells." [AEO:0001010]
xref: AEO:0001010
is_a: UBERON:0034705 {source="AEO"} ! developing neuroepithelium
relationship: has_part CL:0000031 ! neuroblast (sensu Vertebrata)

[Term]
id: UBERON:0034709
name: hindbrain marginal layer
namespace: uberon
synonym: "marginal zone of hindbrain" EXACT [DHBA:12694]
synonym: "MZH" RELATED OMO:0003000 [DHBA:12694]
xref: DHBA:12694
xref: EMAPA:32916
is_a: UBERON:0004062 ! neural tube marginal layer
is_a: UBERON:0011215 ! central nervous system cell part cluster
intersection_of: UBERON:0004062 ! neural tube marginal layer
intersection_of: part_of UBERON:0002028 ! hindbrain
relationship: part_of UBERON:0002028 ! hindbrain

[Term]
id: UBERON:0034710
name: spinal cord ventricular layer
namespace: uberon
synonym: "spinal cord lateral wall ventricular layer" EXACT [EHDAA2:0001267]
xref: EHDAA2:0001267
xref: EMAPA:17585
is_a: UBERON:0004060 ! neural tube ventricular layer
intersection_of: UBERON:0004060 ! neural tube ventricular layer
intersection_of: part_of UBERON:0006241 ! future spinal cord
relationship: part_of UBERON:0005496 {source="EHDAA2"} ! neural tube lateral wall
relationship: part_of UBERON:0006241 ! future spinal cord

[Term]
id: UBERON:0034713
name: cranial neuron projection bundle
namespace: uberon
def: "Any of the cranial nerves, or their central nervous system analogs (the optic tract, the epiphyseal tract). These analogs are not true nerves, and are instead evaginated sensory afferents emanating from the brain." [http://orcid.org/0000-0002-6601-2165, ISBN:0471888893]
subset: human_reference_atlas
synonym: "cranial nerve fiber bundle" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "cranial nerve fiber tract" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "cranial nerve or tract" RELATED [http://orcid.org/0000-0002-6601-2165]
synonym: "neuron projection bundle from brain" RELATED [http://orcid.org/0000-0002-6601-2165]
is_a: UBERON:0000122 ! neuron projection bundle
is_a: UBERON:0015212 ! lateral structure
relationship: extends_fibers_into UBERON:0000955 ! brain
relationship: in_lateral_side_of UBERON:0000033 ! head
relationship: only_in_taxon NCBITaxon:89593 ! Craniata <chordates>
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0000033 ! head
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0034728
name: autonomic nerve
namespace: uberon
def: "The autonomic nerve is a small nerve which carries postganglionic sympathetic and parasympathetic neurons from the zygomaticotemporal nerve; a branch of the maxillary nerve, to the lacrimal nerve; a branch of the ophthalmic nerve. These neurons derive from the superior cervical ganglion and the pterygopalatine ganglion respectively. They will travel to the lacrimal gland via the lacrimal nerve. Parasympathetic will induce lacrimation and vice versa." [Wikipedia:Autonomic_nerve]
synonym: "nervus visceralis" EXACT [FMA:5866]
synonym: "visceral nerve" EXACT [FMA:5866]
xref: EMAPA:37957 {source="MA:th"}
xref: FMA:5866
xref: MESH:D017776
xref: SCTID:276145003
xref: Wikipedia:Autonomic_nerve
is_a: UBERON:0011779 ! nerve of head region
relationship: branching_part_of UBERON:0036264 ! zygomaticotemporal nerve
relationship: extends_fibers_into UBERON:0001805 ! autonomic ganglion
relationship: part_of UBERON:0002410 ! autonomic nervous system
relationship: part_of UBERON:0036264 ! zygomaticotemporal nerve

[Term]
id: UBERON:0034729
name: sympathetic nerve
namespace: uberon
subset: human_reference_atlas
xref: EMAPA:37958 {source="MA:th"}
xref: SCTID:181098007
is_a: UBERON:0001021 ! nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: part_of UBERON:0000013 ! sympathetic nervous system
relationship: extends_fibers_into UBERON:0001806 ! sympathetic ganglion
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0000013 ! sympathetic nervous system
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0034769
name: lymphomyeloid tissue
namespace: uberon
xref: FMA:79770
xref: NCIT:C41168
is_a: UBERON:0015757 {source="FMA"} ! heterogeneous tissue

[Term]
id: UBERON:0034873
name: bodily gas
namespace: uberon
def: "Any substance in the body or expelled from the body that is in a gaseous state." [http://orcid.org/0000-0002-6601-2165]
synonym: "gas in anatomical space" EXACT []
synonym: "portion of gas in anatomical space" EXACT [FMA:84580]
xref: FMA:84580
is_a: UBERON:0000463 ! organism substance
intersection_of: UBERON:0000463 ! organism substance
intersection_of: has_quality PATO:0001547 ! quality of a gas
relationship: has_quality PATO:0001547 ! quality of a gas

[Term]
id: UBERON:0034874
name: air in respiratory system
namespace: uberon
def: "Any portion of gas located in a part of the respiratory system that is composed primarily of air." [http://orcid.org/0000-0002-6601-2165]
synonym: "respiratory air" EXACT [FMA:84581]
synonym: "respiratory system air" EXACT []
xref: FMA:84581
is_a: UBERON:0034947 ! gas in respiratory system
intersection_of: UBERON:0034873 ! bodily gas
intersection_of: composed_primarily_of CHEBI:25805 ! oxygen atom
intersection_of: located_in UBERON:0001004 ! respiratory system
relationship: composed_primarily_of CHEBI:25805 ! oxygen atom

[Term]
id: UBERON:0034878
name: prechordal mesoderm
namespace: uberon
def: "The area of axial mesoderm that develops into the prechordal plate." [MGI:anna]
synonym: "prechordal mesenchyme" EXACT []
is_a: UBERON:0002050 ! embryonic structure
intersection_of: UBERON:0005423 ! developing anatomical structure
intersection_of: has_potential_to_develop_into UBERON:0003063 ! prechordal plate
intersection_of: part_of UBERON:0003068 ! axial mesoderm
relationship: has_potential_to_develop_into UBERON:0003063 ! prechordal plate
relationship: part_of UBERON:0003068 ! axial mesoderm

[Term]
id: UBERON:0034903
name: left atrium endocardium
namespace: uberon
def: "Endocardium that is part of the left atrium." [http://orcid.org/0000-0002-6601-2165]
synonym: "endocardium of left atrium" EXACT [FMA:7286]
synonym: "left atrial endocardium" EXACT []
synonym: "left atrium endocardial tissue" RELATED [VHOG:0001226]
xref: FMA:7286
xref: SCTID:190064008
xref: VHOG:0001226
is_a: UBERON:0002166 ! endocardium of atrium
intersection_of: UBERON:0002165 ! endocardium
intersection_of: part_of UBERON:0002079 ! left cardiac atrium
relationship: part_of UBERON:0002079 ! left cardiac atrium
property_value: UBPROP:0000001 "Endocardium of atrium which is continuous with the tunica intima of the trunk of pulmonary vein." xsd:string {source="FMA:7286"}

[Term]
id: UBERON:0034905
name: gland lumen
namespace: uberon
synonym: "lumen of gland" EXACT []
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0002530 ! gland
relationship: luminal_space_of UBERON:0002530 ! gland
relationship: part_of UBERON:0002530 ! gland

[Term]
id: UBERON:0034921
name: multi organ part structure
namespace: uberon
def: "An multicellular anatomical structure that has subparts of multiple organs as a part." [CARO:0020001]
subset: common_anatomy
synonym: "anatomical cluster" RELATED [CARO:0020001]
xref: CARO:0020001
is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure
relationship: composed_primarily_of UBERON:0000064 ! organ part
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0034922
name: cell cluster
namespace: uberon
def: "A cluster of cells, largely surrounded by a morphological boundary." [CARO:0020002]
subset: common_anatomy
xref: CARO:0020002
xref: FMA:62807
is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure
relationship: surrounded_by UBERON:0000015 ! non-material anatomical boundary
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0034923
name: disconnected anatomical group
namespace: uberon
def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000]
subset: common_anatomy
xref: CARO:0020000
xref: FBbt:00007276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity
relationship: composed_primarily_of UBERON:0000061 ! anatomical structure
relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure
relationship: has_quality PATO:0010001 ! disconnected
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0034925
name: anatomical collection
namespace: uberon
def: "A collection of anatomical structures that are alike in terms of their morphology or developmental origin." [http://orcid.org/0000-0002-6601-2165]
subset: common_anatomy
is_a: UBERON:0000465 ! material anatomical entity
relationship: has_member UBERON:0000061 ! anatomical structure
property_value: editor_note "resolve if this should be a subclass of disconnected anatomical group. Some collections (e.g. the skeleton or skull) are arguably connected" xsd:string
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0034926
name: anatomical row
namespace: uberon
def: "An anatomical collection that is arranged in a line." [http://orcid.org/0000-0002-6601-2165]
subset: common_anatomy
xref: FBbt:00100152 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0034925 ! anatomical collection
property_value: editor_note "resolve if this should be a subclass of or merged with aligned anatomical group." xsd:string
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0034928
name: dorsal surface of penis
namespace: uberon
synonym: "dorsum of penis" EXACT [FMA:19623]
synonym: "dorsum penis" EXACT [FMA:TA]
xref: FMA:19623
is_a: UBERON:0036215 ! anatomical surface region
intersection_of: UBERON:0036215 ! anatomical surface region
intersection_of: in_dorsal_side_of UBERON:0000989 ! penis
relationship: in_dorsal_side_of UBERON:0000989 ! penis
relationship: part_of UBERON:0000989 ! penis

[Term]
id: UBERON:0034929
name: external soft tissue zone
namespace: uberon
def: "A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures." [http://orcid.org/0000-0002-6601-2165]
is_a: PR:000050567 ! protein-containing material entity
is_a: UBERON:0010000 ! multicellular anatomical structure
relationship: has_part UBERON:0000014 ! zone of skin
relationship: has_part UBERON:0001015 ! musculature
relationship: has_part UBERON:0001021 ! nerve
relationship: has_part UBERON:0002049 ! vasculature
relationship: part_of UBERON:0000475 ! organism subdivision

[Term]
id: UBERON:0034932
name: epithelium of biliary system
namespace: uberon
def: "The epithelial layer covering the biliary system. This includes the epithelium of the gallbladder (when present) as well as the intrahepatic and extrahepatic bile ducts." [BTO:0001513, http://orcid.org/0000-0002-6601-2165, MGI:cs]
synonym: "biliary epithelium" RELATED [BTO:0001513]
synonym: "biliary system epithelium" EXACT [http://orcid.org/0000-0002-6601-2165]
synonym: "biliary tract epithelium" RELATED [http://orcid.org/0000-0002-6601-2165]
xref: BTO:0001513
is_a: UBERON:0000483 ! epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0002294 ! biliary system
relationship: part_of UBERON:0002294 ! biliary system

[Term]
id: UBERON:0034933
name: layer of smooth muscle tissue
namespace: uberon
def: "Any organ component layer that consists of smooth muscle tissue." [http://orcid.org/0000-0002-6601-2165]
is_a: UBERON:0018260 ! layer of muscle tissue
intersection_of: UBERON:0004923 ! organ component layer
intersection_of: composed_primarily_of UBERON:0001135 ! smooth muscle tissue
relationship: composed_primarily_of UBERON:0001135 ! smooth muscle tissue

[Term]
id: UBERON:0034944
name: zone of organ
namespace: uberon
synonym: "organ region with floating fiat boundary" RELATED [FMA:55268]
synonym: "organ sector" EXACT [FMA:55268]
synonym: "organ zonal region" EXACT []
synonym: "organ zone" EXACT [FMA:55268]
xref: FMA:55268
is_a: UBERON:0000064 ! organ part

[Term]
id: UBERON:0034945
name: excreted gas
namespace: uberon
def: "Any gaseous product of an excretory process." [http://orcid.org/0000-0002-6601-2165]
is_a: UBERON:0000174 ! excreta
is_a: UBERON:0034873 ! bodily gas
intersection_of: UBERON:0034873 ! bodily gas
intersection_of: output_of GO:0007588 ! excretion

[Term]
id: UBERON:0034946
name: gas excreted from digestive tract
namespace: uberon
def: "Any excreted gas that is produced by the digestive tract." [http://orcid.org/0000-0002-6601-2165]
comment: In mammals, mostly produced as a byproduct of bacterial fermentation in the gastrointestinal (GI) tract, especially the colon, and excreted through the rectum
synonym: "flatulence" NARROW [FMA:78440]
synonym: "flatus" NARROW OMO:0003011 [Wikipedia:Flatulence]
synonym: "intestinal gas" NARROW []
xref: FMA:78440
is_a: UBERON:0034945 ! excreted gas
intersection_of: UBERON:0034945 ! excreted gas
intersection_of: produced_by UBERON:0001555 ! digestive tract
relationship: produced_by UBERON:0001555 ! digestive tract

[Term]
id: UBERON:0034947
name: gas in respiratory system
namespace: uberon
def: "Any portion of gas located in a part of the respiratory system." [http://orcid.org/0000-0002-6601-2165]
synonym: "respiratory gas" EXACT []
synonym: "respiratory system gas" EXACT []
is_a: UBERON:0034873 ! bodily gas
intersection_of: UBERON:0034873 ! bodily gas
intersection_of: located_in UBERON:0001004 ! respiratory system
relationship: located_in UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0034969
name: epithelial layer of duct
namespace: uberon
synonym: "duct epithelium" RELATED []
synonym: "ductal epithelium" RELATED []
xref: NCIT:C25787
xref: UMLS:C1512086
is_a: UBERON:0003914 ! epithelial tube
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0000058 ! duct
relationship: part_of UBERON:0000058 ! duct

[Term]
id: UBERON:0034995
name: jaw mesenchyme
namespace: uberon
def: "Mesenchyme that is part of a developing jaw [Automatically generated definition]." [OBOL:automatic]
xref: EMAPA:32907
xref: EMAPA:35454
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0011595 ! jaw region
relationship: part_of UBERON:0011595 ! jaw region

[Term]
id: UBERON:0035037
name: jaw epithelium
namespace: uberon
xref: EMAPA:32904
xref: MA:0003220
is_a: UBERON:0003929 ! digestive tract epithelium
intersection_of: UBERON:0000483 ! epithelium
intersection_of: part_of UBERON:0011595 ! jaw region
relationship: part_of UBERON:0011595 ! jaw region

[Term]
id: UBERON:0035039
name: rectal artery
namespace: uberon
synonym: "hemorrhoidal artery" EXACT []
xref: SCTID:277967008
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001052 ! rectum
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0001052 ! rectum

[Term]
id: UBERON:0035050
name: excretory duct
namespace: uberon
xref: BTO:0006341 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
is_a: UBERON:0000058 ! duct

[Term]
id: UBERON:0035091
name: extrinsic post-anal tail muscle
namespace: uberon
def: "A post-anal tail that attaches outside the tail." [http://orcid.org/0000-0002-6601-2165]
is_a: UBERON:0003665 ! post-anal tail muscle
intersection_of: UBERON:0003665 ! post-anal tail muscle
intersection_of: attaches_to UBERON:0010742 ! bone of pelvic complex
relationship: attaches_to UBERON:0010742 ! bone of pelvic complex

[Term]
id: UBERON:0035118
name: material entity in digestive tract
namespace: uberon
def: "Any material entity that is located in the digestive tract. This includes undigested food and liquid as well as unexcreted waste products. It also includes other entities such as ingested stones used to aid digestion. Any microbial cells or cell populations are also included." [https://github.com/EnvironmentOntology/envo/issues/110]
synonym: "digestive tract contents" EXACT OMO:0003004 []
synonym: "ingested material entity" RELATED []
is_a: UBERON:0000061 ! anatomical structure
intersection_of: UBERON:0000061 ! anatomical structure
intersection_of: located_in UBERON:0006909 ! lumen of digestive tract
relationship: located_in UBERON:0006909 ! lumen of digestive tract
property_value: editor_note "Note that we treat any material entity that is ingested as an anatomical structure by defintion, although this may be expanding the CARO usage somewhat" xsd:string

[Term]
id: UBERON:0035159
name: entire surface of organism
namespace: uberon
def: "Anatomical surface, which is the external surface of the whole body. Examples: There is only one body surface." [FMA:61695]
synonym: "surface of body" EXACT [FMA:61695]
xref: FMA:61695
xref: NCIT:C29667
xref: SCTID:261060002
xref: UMLS:C0489451
is_a: UBERON:0006984 ! anatomical surface
intersection_of: UBERON:0006984 ! anatomical surface
intersection_of: surrounds UBERON:0000468 ! multicellular organism
relationship: surrounds UBERON:0000468 ! multicellular organism

[Term]
id: UBERON:0035398
name: branch of external carotid artery
namespace: uberon
synonym: "external carotid arterial subdivision" EXACT [FMA:70505]
synonym: "subdivision of external carotid artery" EXACT [FMA:70505]
xref: FMA:70505
xref: NCIT:C32552
xref: SCTID:244216003
xref: UMLS:C0447038
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: connecting_branch_of UBERON:0001070 ! external carotid artery
relationship: connecting_branch_of UBERON:0001070 ! external carotid artery
relationship: part_of RO:0002577 ! system

[Term]
id: UBERON:0035431
name: mediastinal pleura
namespace: uberon
def: "The parietal pleura that lines the mediastinum." [ncithesaurus:Mediastinal_Pleura]
synonym: "mediastinal part of parietal pleura" EXACT [FMA:9736]
synonym: "pars mediastinalis (pleurae)" EXACT [FMA:9736]
synonym: "pars mediastinalis pleurae parietalis" EXACT OMO:0003011 [FMA:9736, FMA:TA]
xref: FMA:9736
xref: NCIT:C94820
xref: SCTID:362002008
xref: UMLS:C0225789
xref: Wikipedia:Mediastinal_pleura
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0034944 ! zone of organ
relationship: has_part UBERON:0003728 {source="FMA"} ! mediastinum
relationship: part_of UBERON:0002400 {source="FMA"} ! parietal pleura

[Term]
id: UBERON:0035471
name: posterior surface of kidney
namespace: uberon
synonym: "facies posterior (Ren)" EXACT [FMA:15590]
synonym: "facies posterior renis" EXACT OMO:0003011 [FMA:15590, FMA:TA]
xref: FMA:15590
xref: NCIT:C32895
xref: SCTID:279376000
xref: UMLS:C0227610
is_a: UBERON:0036215 ! anatomical surface region
intersection_of: UBERON:0036215 ! anatomical surface region
intersection_of: bounding_layer_of UBERON:0002113 ! kidney
intersection_of: in_posterior_side_of UBERON:0002113 ! kidney
relationship: bounding_layer_of UBERON:0002113 ! kidney
relationship: in_posterior_side_of UBERON:0002113 ! kidney
relationship: part_of UBERON:0002113 ! kidney

[Term]
id: UBERON:0035539
name: esophageal artery
namespace: uberon
def: "Any of several arteries that arise from the aorta and supply blood to the esophagus." [ncithesaurus:Esophageal_Artery]
subset: human_reference_atlas
synonym: "aortic esophageal artery" EXACT [FMA:4149]
synonym: "oesophageal artery" EXACT [FMA:4149]
xref: FMA:4149
xref: NCIT:C32535
xref: SCTID:56548006
xref: UMLS:C0226294
is_a: UBERON:0003834 ! thoracic segment blood vessel
is_a: UBERON:0004573 {source="FMA"} ! systemic artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001043 ! esophagus
relationship: branching_part_of UBERON:0001515 {source="FMA"} ! thoracic aorta
relationship: connected_to UBERON:0002345 ! descending thoracic aorta
relationship: part_of UBERON:0001515 ! thoracic aorta
relationship: supplies UBERON:0001043 ! esophagus
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0035546
name: uveal vein
namespace: uberon
synonym: "ciliary vein" EXACT [FMA:51797]
xref: FMA:51797
xref: SCTID:149683007
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0001768 ! uvea
relationship: drains UBERON:0001768 ! uvea
relationship: part_of RO:0002577 ! system

[Term]
id: UBERON:0035548
name: colic artery
namespace: uberon
xref: SCTID:77852007
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001155 ! colon
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0001155 ! colon
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI

[Term]
id: UBERON:0035549
name: vasculature of integument
namespace: uberon
def: "The part of the circulatory system that lies within the subcutaneous tissue layers close to the surface of the skin." [http://orcid.org/0000-0002-6601-2165]
subset: human_reference_atlas
synonym: "dermis vasculature" NARROW []
synonym: "hypodermis vasculature" NARROW []
synonym: "skin vasculature" RELATED []
synonym: "subcutaneous vasculature" RELATED []
synonym: "superficial part of circulatory system" EXACT []
synonym: "superficial vasculature" EXACT []
synonym: "vasculature of skin" RELATED [FMA:225275]
xref: FMA:225275
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: located_in UBERON:0002199 ! integument
relationship: capable_of_part_of GO:0001659 ! temperature homeostasis
relationship: located_in UBERON:0002199 ! integument
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0035550
name: superficial vein
namespace: uberon
def: "Any of the veins carrying deoxygenated blood from the subcutaneous tissue layers." [ncithesaurus:Superficial_Vein]
synonym: "superfical vein" RELATED [Wikipedia:Superficial_vein]
synonym: "superficial veins" RELATED [Wikipedia:Superficial_vein]
synonym: "superficial vessels" RELATED [Wikipedia:Superficial_vein]
xref: FMA:76719
xref: NCIT:C33666
xref: SCTID:341382008
xref: UMLS:C0226513
xref: Wikipedia:Superficial_vein
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0035549 ! vasculature of integument
relationship: part_of UBERON:0035549 ! vasculature of integument

[Term]
id: UBERON:0035551
name: deep vasculature
namespace: uberon
def: "The part of the circulatory system that lies deep beneath the subcutaneous tissue layers away from the surface of the skin." [http://orcid.org/0000-0002-6601-2165]
synonym: "deep part of circulatory system" EXACT []
is_a: UBERON:0002049 ! vasculature
intersection_of: UBERON:0002049 ! vasculature
intersection_of: deep_to UBERON:0002199 ! integument
relationship: deep_to UBERON:0002199 ! integument

[Term]
id: UBERON:0035552
name: deep vein
namespace: uberon
def: "A blood vessel carrying deoxygenated blood far beneath the skin usually accompanying an artery." [ncithesaurus:Deep_Vein]
synonym: "deep veins" RELATED [Wikipedia:Deep_vein]
synonym: "deep vessels" RELATED [Wikipedia:Deep_vein]
xref: FMA:76718
xref: NCIT:C32444
xref: SCTID:341484008
xref: UMLS:C0226514
xref: Wikipedia:Deep_vein
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0035551 ! deep vasculature
relationship: part_of UBERON:0035551 ! deep vasculature

[Term]
id: UBERON:0035553
name: left cardiac chamber
namespace: uberon
def: "Any chamber of the left side of the heart." [http://orcid.org/0000-0002-6601-2165]
xref: FMA:7166
xref: SCTID:362008007
is_a: UBERON:0004151 ! cardiac chamber
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0004151 ! cardiac chamber
intersection_of: in_left_side_of UBERON:0000948 ! heart
relationship: in_left_side_of UBERON:0000948 ! heart

[Term]
id: UBERON:0035554
name: right cardiac chamber
namespace: uberon
def: "Any chamber of the right side of the heart." [http://orcid.org/0000-0002-6601-2165]
xref: FMA:7165
xref: SCTID:362007002
is_a: UBERON:0004151 ! cardiac chamber
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0004151 ! cardiac chamber
intersection_of: in_right_side_of UBERON:0000948 ! heart
relationship: in_right_side_of UBERON:0000948 ! heart

[Term]
id: UBERON:0035639
name: ocular adnexa
namespace: uberon
def: "The parts of the orbital region that are outside of the the eyeball, including the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva." [HPO:pr, http://medical-dictionary.thefreedictionary.com/ocular+adnexa, https://github.com/obophenotype/uberon/issues/1132, UBERON:cjm]
synonym: "accessory parts of orbital region" RELATED []
synonym: "accessory visual structures" RELATED [FMA:76554, Wikipedia:Accessory_visual_structures]
synonym: "accessory visual structures set" RELATED [FMA:76554]
synonym: "adnexa oculi" EXACT OMO:0003011 [http://medical-dictionary.thefreedictionary.com/ocular+adnexa]
synonym: "adnexal parts of orbital region" RELATED []
synonym: "appendage of eye" RELATED [http://medical-dictionary.thefreedictionary.com/ocular+adnexa]
synonym: "appendages of the eye" RELATED OMO:0003004 [http://medical-dictionary.thefreedictionary.com/ocular+adnexa]
synonym: "eye adnexa" RELATED []
synonym: "set of accessory visual structures" RELATED [FMA:76554]
synonym: "structurae oculi accessoriae" RELATED OMO:0003011 [Wikipedia:Accessory_visual_structures]
xref: FMA:76554
xref: NCIT:C32574
xref: SCTID:120612006
xref: UMLS:C0229243
xref: Wikipedia:Accessory_visual_structures
is_a: UBERON:0034921 ! multi organ part structure
relationship: part_of UBERON:0004088 ! orbital region

[Term]
id: UBERON:0035649
name: nerve of penis
namespace: uberon
def: "Any nerve that innervates the penis." [UBERON:cjm]
synonym: "penile nerve" EXACT []
synonym: "penis nerve" EXACT []
xref: EMAPA:35057
is_a: UBERON:0001021 ! nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: innervates UBERON:0000989 ! penis
relationship: innervates UBERON:0000989 ! penis

[Term]
id: UBERON:0035650
name: nerve of clitoris
namespace: uberon
def: "Any nerve that innervates the clitoris." [UBERON:cjm]
subset: human_reference_atlas
synonym: "clitoral nerve" EXACT []
synonym: "clitoris nerve" EXACT []
xref: EMAPA:35044
is_a: UBERON:0001021 ! nerve
intersection_of: UBERON:0001021 ! nerve
intersection_of: innervates UBERON:0002411 ! clitoris
relationship: innervates UBERON:0002411 ! clitoris
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0035651
name: glans
namespace: uberon
xref: Wikipedia:Glans
is_a: UBERON:0000063 ! organ subunit
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
union_of: UBERON:0001299 ! glans penis
union_of: UBERON:0006653 ! glans clitoris
relationship: develops_from UBERON:0013238 ! future glans
relationship: part_of UBERON:0003133 ! reproductive organ

[Term]
id: UBERON:0035763
name: cavity of cardiac chamber
namespace: uberon
synonym: "cardiac chamber cavity" EXACT [FMA:9464]
synonym: "heart cavity" EXACT [FMA:9464]
synonym: "heart lumen" EXACT [EHDAA2:0004181]
xref: EHDAA2:0004181
xref: FMA:9464
is_a: UBERON:0002553 ! anatomical cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0004151 ! cardiac chamber
relationship: luminal_space_of UBERON:0004151 ! cardiac chamber
relationship: part_of UBERON:0004151 ! cardiac chamber
relationship: surrounded_by UBERON:0002165 {source="FMA"} ! endocardium

[Term]
id: UBERON:0035804
name: future mouth
namespace: uberon
def: "The primordial mouth region of the developing head." [MP:0003119]
synonym: "primitive mouth" EXACT [FMA:293105]
synonym: "primordial mouth" EXACT []
xref: FMA:293105
is_a: UBERON:0013522 ! subdivision of tube
relationship: has_part UBERON:0000925 ! endoderm
relationship: has_part UBERON:0000930 ! stomodeum
relationship: part_of UBERON:0007026 ! presumptive gut

[Term]
id: UBERON:0035805
name: muscle layer of sigmoid colon
namespace: uberon
def: "A muscle layer that is part of the sigmoid colon." [https://github.com/obophenotype/uberon/issues/1162]
synonym: "muscularis externa of sigmoid colon" EXACT [FMA:15028]
synonym: "muscularis propria of sigmoid colon" EXACT []
synonym: "sigmoid colon muscularis propria" EXACT []
synonym: "sigmoideum muscularis" RELATED []
synonym: "tunica muscularis colon sigmoideum" RELATED []
xref: FMA:15028
is_a: UBERON:0012489 ! muscle layer of colon
intersection_of: UBERON:0006660 ! muscular coat
intersection_of: part_of UBERON:0001159 ! sigmoid colon
relationship: part_of UBERON:0001159 ! sigmoid colon

[Term]
id: UBERON:0035809
name: serous cavity
namespace: uberon
xref: FMA:12241
xref: SCTID:304404008
is_a: UBERON:0002553 ! anatomical cavity
intersection_of: UBERON:0002553 ! anatomical cavity
intersection_of: luminal_space_of UBERON:0005906 ! serous sac
relationship: luminal_space_of UBERON:0005906 ! serous sac
relationship: part_of UBERON:0005906 ! serous sac

[Term]
id: UBERON:0035814
name: pericardial fat
namespace: uberon
def: "The sum of epicardial and paracardial fat deposits." [DOI:10.5935/abc.20130138]
xref: SCTID:42267001
xref: ZFA:0005765
is_a: UBERON:0035818 ! visceral fat
intersection_of: UBERON:0001013 ! adipose tissue
intersection_of: surrounds UBERON:0000948 ! heart
relationship: surrounds UBERON:0000948 ! heart

[Term]
id: UBERON:0035815
name: paracardial fat
namespace: uberon
def: "Fat deposits in the mediastinum outside the parietal pericardium ." [DOI:10.5935/abc.20130138]
synonym: "intrathoracic fat" EXACT [DOI:10.5935/abc.20130138]
is_a: UBERON:0035814 ! pericardial fat
intersection_of: UBERON:0001013 ! adipose tissue
intersection_of: adjacent_to UBERON:0002408 ! parietal serous pericardium
intersection_of: surrounds UBERON:0000948 ! heart
relationship: adjacent_to UBERON:0002408 ! parietal serous pericardium

[Term]
id: UBERON:0035818
name: visceral fat
namespace: uberon
def: "Any fat deposit surrounding a visceral organ." [UBERON:cjm]
is_a: UBERON:0001013 ! adipose tissue
intersection_of: UBERON:0001013 ! adipose tissue
intersection_of: surrounds UBERON:0000062 ! organ
relationship: surrounds UBERON:0000062 ! organ

[Term]
id: UBERON:0035819
name: abdominopelvic cavity
namespace: uberon
def: "The part of the ventral body cavity that is within the abdominal segment of the trunk, which encompasses the abdomen proper plus pelvic cavity." [UBERON:cjm]
synonym: "cavitas abdominis et pelvis" EXACT OMO:0003011 [FMA:TA]
xref: FMA:12267
xref: Wikipedia:Abdominopelvic_cavity
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0002417 ! abdominal segment of trunk
intersection_of: part_of UBERON:0002323 ! coelemic cavity lumen
relationship: luminal_space_of UBERON:0002417 ! abdominal segment of trunk
relationship: part_of UBERON:0002323 ! coelemic cavity lumen
relationship: part_of UBERON:0002417 ! abdominal segment of trunk

[Term]
id: UBERON:0035820
name: peritoneal sac
namespace: uberon
def: "A serous sac that is the aggregate of the peritoneum and the peritoneal cavity, located in the abdominal cavity." [https://github.com/obophenotype/uberon/issues/86]
synonym: "peritoneal component" RELATED [EMAPA:16137]
xref: EMAPA:16137
xref: FMA:9908
is_a: UBERON:0002075 ! viscus
is_a: UBERON:0005906 ! serous sac
relationship: has_part UBERON:0001179 ! peritoneal cavity
relationship: has_part UBERON:0002358 ! peritoneum
relationship: located_in UBERON:0003684 ! abdominal cavity

[Term]
id: UBERON:0035956
name: epididymal lumen
namespace: uberon
def: "The lumen of the epididymis." [GOC:DOS, https://github.com/obophenotype/uberon/issues/1209]
synonym: "epididymis lumen" EXACT [FMA:18274]
synonym: "lumen of epididymis" EXACT [FMA:18274]
xref: FMA:18274
xref: SCTID:367722009
is_a: UBERON:0000464 ! anatomical space
intersection_of: UBERON:0000464 ! anatomical space
intersection_of: luminal_space_of UBERON:0001301 ! epididymis
relationship: location_of UBERON:0006530 {source="FMA"} ! seminal fluid
relationship: luminal_space_of UBERON:0001301 ! epididymis
relationship: part_of UBERON:0001301 ! epididymis

[Term]
id: UBERON:0035965
name: wall of blood vessel
namespace: uberon
synonym: "blood vessel wall" EXACT [FMA:67473]
synonym: "vascular wall" RELATED [BTO:0004378]
xref: BTO:0004378
xref: EMAPA:37987 {source="MA:th"}
xref: FMA:67473
is_a: UBERON:0000060 ! anatomical wall
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001981 ! blood vessel
relationship: composed_primarily_of UBERON:0004797 ! blood vessel layer
relationship: part_of UBERON:0001981 ! blood vessel

[Term]
id: UBERON:0036072
name: respiratory primordium epithelium
namespace: uberon
xref: EHDAA2:0004070
is_a: UBERON:0004185 ! endodermal part of digestive tract
is_a: UBERON:0005911 ! endo-epithelium
is_a: UBERON:0007499 ! epithelial sac
is_a: UBERON:0009854 ! digestive tract diverticulum
is_a: UBERON:0015833 ! foregut epithelium
intersection_of: UBERON:0007499 ! epithelial sac
intersection_of: part_of UBERON:0008947 ! respiratory primordium
relationship: develops_from UBERON:0007690 {source="EHDAA2"} ! early pharyngeal endoderm
relationship: part_of UBERON:0008947 ! respiratory primordium

[Term]
id: UBERON:0036073
name: respiratory primordium mesenchyme
namespace: uberon
synonym: "respiratory primordium associated mesenchyme" EXACT [EHDAA2:0004071]
xref: EHDAA2:0004071
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
is_a: UBERON:0003104 ! mesenchyme
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0008947 ! respiratory primordium
relationship: develops_from UBERON:0004873 {source="EHDAA2"} ! splanchnopleure
relationship: part_of UBERON:0008947 ! respiratory primordium

[Term]
id: UBERON:0036146
name: cardiopharyngeal field
namespace: uberon
def: "An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles." [http://www.nature.com/nature/journal/v520/n7548/full/nature14435.html#bx1, https://orcid.org/0000-0003-3308-6245]
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005291 ! embryonic tissue
is_a: UBERON:0007688 ! anlage

[Term]
id: UBERON:0036186
name: fibroelastic connective tissue
namespace: uberon
xref: FMA:83520
is_a: UBERON:0002521 ! elastic tissue
is_a: UBERON:0011824 ! fibrous connective tissue
intersection_of: UBERON:0011824 ! fibrous connective tissue
intersection_of: composed_primarily_of GO:0071953 ! elastic fiber

[Term]
id: UBERON:0036214
name: rectosigmoid junction
namespace: uberon
def: "An anatomical junction that is between the sigmoid colon and rectum." [https://github.com/obophenotype/uberon/issues/1319, https://www.cdc.gov/cancer/npcr/pdf/abstracting/colon.pdf, NCIT:C54188]
synonym: "rectosigmoid region" RELATED [NCIT:C54188]
xref: NCIT:C54188
xref: SCTID:245429006
is_a: UBERON:8410024 ! intestinal junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0001052 ! rectum
intersection_of: connects UBERON:0001159 ! sigmoid colon
relationship: connects UBERON:0001052 ! rectum
relationship: connects UBERON:0001159 ! sigmoid colon

[Term]
id: UBERON:0036215
name: anatomical surface region
namespace: uberon
def: "Material anatomical entity that forms the outermost boundary of an anatomical structure." [https://github.com/obophenotype/uberon/issues/1324]
subset: common_anatomy
xref: AAO:0010270
xref: ZFA:0005594
is_a: UBERON:0000465 ! material anatomical entity
relationship: bounding_layer_of UBERON:0000061 ! anatomical structure
relationship: part_of UBERON:0000061 ! anatomical structure
property_value: RO:0002175 NCBITaxon:33090
property_value: RO:0002175 NCBITaxon:33208
property_value: RO:0002175 NCBITaxon:4751

[Term]
id: UBERON:0036217
name: coelomic fluid
namespace: uberon
def: "A bodily fluid that is located in the coelom." [https://github.com/obophenotype/uberon/issues/1326, PMID:10874572]
xref: BTO:0001708
is_a: UBERON:0006314 ! bodily fluid
intersection_of: UBERON:0006314 ! bodily fluid
intersection_of: located_in UBERON:0011997 ! coelom
relationship: located_in UBERON:0011997 ! coelom
property_value: UBPROP:0000009 "he coelomic fluid serves several functions; it acts as a hydroskeleton, it allows free movement and growth of internal organs, it serves for transport of gases, nutrients and waste products between different parts of the body, it allows storage of sperm and eggs during maturation and it acts as a reservoir for waste [Wikipedia:Coelom#Coelomic_fluid]" xsd:string

[Term]
id: UBERON:0036225
name: respiratory system gland
namespace: uberon
def: "Any gland that is part os the respiratory system." [UBERON:cjm]
is_a: UBERON:0002530 ! gland
intersection_of: UBERON:0002530 ! gland
intersection_of: part_of UBERON:0001004 ! respiratory system
relationship: part_of UBERON:0001004 ! respiratory system

[Term]
id: UBERON:0036242
name: post-embryonic notochord
namespace: uberon
def: "A notochord that has persisted beyond the embryonic stage." [UBERON:cjm]
is_a: UBERON:0002328 ! notochord
intersection_of: UBERON:0002328 ! notochord
intersection_of: part_of UBERON:0009953 ! post-embryonic organism
relationship: part_of UBERON:0009953 ! post-embryonic organism
property_value: RO:0002161 NCBITaxon:32524
property_value: RO:0002175 NCBITaxon:118072
property_value: RO:0002175 NCBITaxon:7737
property_value: RO:0002175 NCBITaxon:7746
property_value: RO:0002175 NCBITaxon:7878
property_value: RO:0002175 NCBITaxon:8292

[Term]
id: UBERON:0036244
name: secretion of serous membrane
namespace: uberon
def: "A transudate found in the serous sac." [FMA:20932]
synonym: "serous fluid" BROAD [FMA:20932]
synonym: "serous sac fluid" EXACT []
xref: FMA:20932
is_a: UBERON:0007779 ! transudate
intersection_of: UBERON:0007779 ! transudate
intersection_of: filtered_through UBERON:0000042 ! serous membrane
relationship: filtered_through UBERON:0000042 ! serous membrane
relationship: located_in UBERON:0005906 ! serous sac

[Term]
id: UBERON:0036253
name: orifice of skull
namespace: uberon
synonym: "cranial orifice" EXACT [FMA:53133]
synonym: "skull orifice" EXACT [FMA:53133]
xref: FMA:53133
is_a: UBERON:0000161 ! orifice
intersection_of: UBERON:0000161 ! orifice
intersection_of: part_of UBERON:0003129 ! skull
relationship: part_of UBERON:0003129 ! skull

[Term]
id: UBERON:0036264
name: zygomaticotemporal nerve
namespace: uberon
def: "The zygomaticotemporal nerve or zygomaticotemporal branch (temporal branch) is derived from the maxillary branch of the trigeminal nerve (Cranial nerve V). It runs along the lateral wall of the orbit in a groove in the zygomatic bone, receives a branch of communication from the lacrimal, and passes through zygomaticotemporal foramen in the zygomatic bone to enter the temporal fossa. It ascends between the bone, and substance of the Temporalis muscle, pierces the temporal fascia about 2.5 cm. above the zygomatic arch, and is distributed to the skin of the side of the forehead, and communicates with the facial nerve and with the auriculotemporal branch of the mandibular nerve. As it pierces the temporal fascia, it gives off a slender twig, which runs between the two layers of the fascia to the lateral angle of the orbit." [Wikipedia:Zygomaticotemporal_nerve]
synonym: "ramus zygomaticotemporalis (Nervus zygomaticus)" EXACT [FMA:52972]
synonym: "ramus zygomaticotemporalis nervus zygomatici" EXACT OMO:0003011 [FMA:TA]
synonym: "zygomaticotemporal" RELATED [Wikipedia:Zygomaticotemporal_nerve]
synonym: "zygomaticotemporal branch" RELATED [Wikipedia:Zygomaticotemporal_nerve]
synonym: "zygomaticotemporal branch of zygomatic nerve" EXACT [FMA:52972]
xref: FMA:52972
xref: SCTID:280243001
xref: Wikipedia:Zygomaticotemporal_nerve
is_a: UBERON:0011779 ! nerve of head region
relationship: branching_part_of UBERON:0000377 ! maxillary nerve
relationship: part_of UBERON:0000377 ! maxillary nerve

[Term]
id: UBERON:0036267
name: vulval vein
namespace: uberon
xref: SCTID:279975006
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0000997 ! mammalian vulva
relationship: drains UBERON:0000997 ! mammalian vulva
relationship: part_of RO:0002577 ! system

[Term]
id: UBERON:0036268
name: pelvic vein
namespace: uberon
xref: SCTID:13152008
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0002355 ! pelvic region of trunk
relationship: drains UBERON:0002355 ! pelvic region of trunk
relationship: part_of RO:0002577 ! system

[Term]
id: UBERON:0036269
name: penis blood vessel
namespace: uberon
synonym: "penis vasculature" RELATED []
synonym: "vasculature of penis" RELATED [EMAPA:30807]
xref: EMAPA:30807
xref: SCTID:363673006
is_a: UBERON:0001981 ! blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: connected_to UBERON:0000989 ! penis
relationship: connected_to UBERON:0000989 ! penis
relationship: part_of RO:0002577 ! system

[Term]
id: UBERON:0036285
name: wall of left ventricle
namespace: uberon
def: "Wall of ventricle which is continuous with the wall of aorta." [FMA:9556]
synonym: "left ventricular wall" EXACT [FMA:9556]
xref: FMA:9556
is_a: UBERON:0004784 {source="FMA"} ! heart ventricle wall
intersection_of: UBERON:0004784 ! heart ventricle wall
intersection_of: part_of UBERON:0002084 ! heart left ventricle
relationship: part_of UBERON:0002084 {source="FMA"} ! heart left ventricle

[Term]
id: UBERON:0036286
name: wall of right ventricle
namespace: uberon
def: "Wall of ventricle which is continuous with the wall of pulmonary trunk." [FMA:9533]
synonym: "right ventricular wall" EXACT [FMA:9533]
xref: FMA:9533
is_a: UBERON:0004784 {source="FMA"} ! heart ventricle wall
intersection_of: UBERON:0004784 ! heart ventricle wall
intersection_of: part_of UBERON:0002080 ! heart right ventricle
relationship: part_of UBERON:0002080 {source="FMA"} ! heart right ventricle

[Term]
id: UBERON:0036288
name: anterior wall of left ventricle
namespace: uberon
xref: FMA:9560
is_a: UBERON:0036285 ! wall of left ventricle
intersection_of: UBERON:0004784 ! heart ventricle wall
intersection_of: in_anterior_side_of UBERON:0002084 ! heart left ventricle
relationship: in_anterior_side_of UBERON:0002084 ! heart left ventricle
relationship: part_of UBERON:0036285 {source="FMA"} ! wall of left ventricle

[Term]
id: UBERON:0036289
name: anterior wall of right ventricle
namespace: uberon
def: "Region of wall of right ventricle which is continuous with the lateral and septal walls of right ventricle." [FMA:9553]
xref: FMA:9553
is_a: UBERON:0036286 ! wall of right ventricle
intersection_of: UBERON:0004784 ! heart ventricle wall
intersection_of: in_anterior_side_of UBERON:0002080 ! heart right ventricle
relationship: in_anterior_side_of UBERON:0002080 ! heart right ventricle

[Term]
id: UBERON:0036290
name: myocardium of anterior wall of left ventricle
namespace: uberon
xref: FMA:87177
is_a: UBERON:0006566 ! left ventricle myocardium
intersection_of: UBERON:0002349 ! myocardium
intersection_of: part_of UBERON:0036288 ! anterior wall of left ventricle
relationship: part_of UBERON:0036288 ! anterior wall of left ventricle

[Term]
id: UBERON:0036291
name: myocardium of anterior wall of right ventricle
namespace: uberon
xref: FMA:260877
is_a: UBERON:0006567 ! right ventricle myocardium
intersection_of: UBERON:0002349 ! myocardium
intersection_of: part_of UBERON:0036289 ! anterior wall of right ventricle
relationship: part_of UBERON:0036289 ! anterior wall of right ventricle

[Term]
id: UBERON:0036294
name: mucosa of lip
namespace: uberon
def: "A mucosa that is part of a lip region [Automatically generated definition]." [OBOL:automatic]
synonym: "labial mucosa" EXACT [UBERON:cjm]
xref: NCIT:C12226
is_a: UBERON:0003729 ! mouth mucosa
intersection_of: UBERON:0000344 ! mucosa
intersection_of: part_of UBERON:0001833 ! lip
relationship: part_of UBERON:0001833 ! lip

[Term]
id: UBERON:0036295
name: renal pelvis/ureter
namespace: uberon
def: "The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra." [NCIT:C54419]
subset: human_reference_atlas
synonym: "renal pelvis and ureter" EXACT []
synonym: "renal pelvis plus ureter" EXACT []
xref: NCIT:C54419
is_a: UBERON:0000477 ! anatomical cluster
relationship: part_of UBERON:0011143 {source="NCIT"} ! upper urinary tract
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0036301
name: vasculature of spleen
namespace: uberon
xref: FMA:225251
xref: SCTID:297287005
is_a: UBERON:0002201 ! vasculature of trunk
is_a: UBERON:0006876 {source="FMA"} ! vasculature of organ
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0002106 ! spleen
relationship: part_of UBERON:0002106 ! spleen

[Term]
id: UBERON:0036302
name: vasculature of central nervous system plus retina
namespace: uberon
is_a: UBERON:0002049 ! vasculature
union_of: UBERON:0004864 ! vasculature of retina
union_of: UBERON:0036303 ! vasculature of central nervous system

[Term]
id: UBERON:0036303
name: vasculature of central nervous system
namespace: uberon
xref: FMA:259905
is_a: UBERON:0036302 ! vasculature of central nervous system plus retina
intersection_of: UBERON:0002049 ! vasculature
intersection_of: part_of UBERON:0001017 ! central nervous system
relationship: part_of UBERON:0001017 ! central nervous system

[Term]
id: UBERON:0036343
name: wall of gallbladder
namespace: uberon
synonym: "gallbladder wall" EXACT [FMA:14657]
xref: FMA:14657
is_a: UBERON:0003697 ! abdominal wall
is_a: UBERON:0004119 ! endoderm-derived structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0002110 ! gallbladder
relationship: part_of UBERON:0002110 {source="FMA"} ! gallbladder

[Term]
id: UBERON:0036351
name: wall of brachiocephalic artery
namespace: uberon
synonym: "brachiocephalic arterial wall" EXACT [FMA:15089]
xref: FMA:15089
is_a: UBERON:0000415 {source="FMA"} ! artery wall
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001529 ! brachiocephalic artery
relationship: part_of UBERON:0001529 {source="FMA"} ! brachiocephalic artery

[Term]
id: UBERON:0036352
name: wall of subclavian artery
namespace: uberon
synonym: "subclavian arterial wall" EXACT [FMA:15090]
xref: FMA:15090
is_a: UBERON:0000415 {source="FMA"} ! artery wall
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001533 ! subclavian artery
relationship: part_of UBERON:0001533 {source="FMA"} ! subclavian artery

[Term]
id: UBERON:0036362
name: wall of anal canal
namespace: uberon
synonym: "anal canal wall" EXACT [FMA:15704]
xref: FMA:15704
is_a: UBERON:0001169 ! wall of large intestine
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000159 ! anal canal
intersection_of: part_of UBERON:0001007 ! digestive system
relationship: part_of UBERON:0000159 {source="FMA"} ! anal canal

[Term]
id: UBERON:0036375
name: wall of right ureter
namespace: uberon
synonym: "right ureteral wall" EXACT [FMA:15889]
xref: FMA:15889
is_a: UBERON:0009916 {source="FMA"} ! wall of ureter
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001222 ! right ureter
relationship: part_of UBERON:0001222 {source="FMA"} ! right ureter

[Term]
id: UBERON:0036376
name: wall of left ureter
namespace: uberon
subset: human_reference_atlas
synonym: "left ureteral wall" EXACT [FMA:15890]
xref: FMA:15890
is_a: UBERON:0009916 {source="FMA"} ! wall of ureter
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001223 ! left ureter
relationship: part_of UBERON:0001223 {source="FMA"} ! left ureter
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:0036422
name: wall of pulmonary artery
namespace: uberon
synonym: "pulmonary arterial wall" EXACT [FMA:18211]
xref: FMA:18211
is_a: UBERON:0000415 {source="FMA"} ! artery wall
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0002012 ! pulmonary artery
relationship: part_of UBERON:0002012 {source="FMA"} ! pulmonary artery

[Term]
id: UBERON:0036441
name: wall of uterine tube
namespace: uberon
synonym: "uterine tube wall" EXACT [FMA:18303]
synonym: "wall of fallopian tube" EXACT [FMA:18303]
synonym: "wall of oviduct" EXACT [FMA:18303]
xref: FMA:18303
is_a: UBERON:0000060 {source="FMA"} ! anatomical wall
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0003889 ! fallopian tube
relationship: part_of UBERON:0003889 {source="FMA"} ! fallopian tube

[Term]
id: UBERON:0036521
name: wall of urethra
namespace: uberon
synonym: "urethral wall" EXACT [FMA:19779]
xref: FMA:19779
is_a: UBERON:0000060 {source="FMA"} ! anatomical wall
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000057 ! urethra
relationship: part_of UBERON:0000057 {source="FMA"} ! urethra

[Term]
id: UBERON:0036553
name: wall of synovial tendon sheath
namespace: uberon
xref: FMA:231590
is_a: UBERON:0000042 {source="FMA"} ! serous membrane
is_a: UBERON:0000060 ! anatomical wall
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000304 ! tendon sheath
relationship: part_of UBERON:0000304 {source="FMA"} ! tendon sheath

[Term]
id: UBERON:0036925
name: wall of eyeball
namespace: uberon
synonym: "eyeball wall" EXACT [FMA:58098]
xref: FMA:58098
is_a: UBERON:0000060 {source="FMA"} ! anatomical wall
is_a: UBERON:0004121 ! ectoderm-derived structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0010230 ! eyeball of camera-type eye
relationship: part_of UBERON:0010230 {source="FMA"} ! eyeball of camera-type eye

[Term]
id: UBERON:0037089
name: wall of orbit
namespace: uberon
synonym: "orbit wall" EXACT [FMA:63144]
xref: FMA:63144
is_a: UBERON:0000060 ! anatomical wall
is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system
is_a: UBERON:0010313 ! neural crest-derived structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001697 ! orbit of skull
relationship: part_of UBERON:0001697 {source="FMA"} ! orbit of skull

[Term]
id: UBERON:0037094
name: wall of common carotid artery
namespace: uberon
synonym: "common carotid arterial wall" EXACT [FMA:66284]
xref: FMA:66284
is_a: UBERON:0000415 {source="FMA"} ! artery wall
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001530 ! common carotid artery plus branches
relationship: part_of UBERON:0001530 {source="FMA"} ! common carotid artery plus branches

[Term]
id: UBERON:0037144
name: wall of heart
namespace: uberon
def: "Wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees." [FMA:7274]
synonym: "cardiac wall" EXACT [FMA:7274]
xref: FMA:7274
is_a: UBERON:0000060 {source="FMA"} ! anatomical wall
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0000948 ! heart
relationship: attaches_to UBERON:0002406 {source="FMA"} ! pericardial sac
relationship: attaches_to UBERON:0004292 {source="FMA"} ! cardiac skeleton
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0000948 {source="FMA"} ! heart

[Term]
id: UBERON:0037447
name: wall of male urethra
namespace: uberon
synonym: "male urethral wall" EXACT [FMA:19676]
xref: FMA:19676
is_a: UBERON:0036521 {source="FMA"} ! wall of urethra
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001333 ! male urethra
relationship: part_of UBERON:0001333 {source="FMA"} ! male urethra

[Term]
id: UBERON:0037455
name: wall of female urethra
namespace: uberon
synonym: "female urethral wall" EXACT [FMA:19780]
xref: FMA:19780
is_a: UBERON:0036521 {source="FMA"} ! wall of urethra
intersection_of: UBERON:0000060 ! anatomical wall
intersection_of: part_of UBERON:0001334 ! female urethra
relationship: part_of UBERON:0001334 {source="FMA"} ! female urethra

[Term]
id: UBERON:0039222
name: cystic artery
namespace: uberon
def: "An artery that supplies oxygenated blood to the cystic duct." [http://orcid.org/0000-0002-6601-2165, https://en.wikipedia.org/wiki/Cystic_artery]
synonym: "cholecystic artery" EXACT [FMA:14835]
xref: FMA:14835
is_a: UBERON:0001637 ! artery
is_a: UBERON:0015796 ! liver blood vessel
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001152 ! cystic duct
relationship: part_of UBERON:0015482 {source="FMA", source="Wikipedia"} ! right hepatic artery
relationship: supplies UBERON:0001152 ! cystic duct
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb" xsd:anyURI
property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb" xsd:anyURI

[Term]
id: UBERON:0039228
name: sigmoid vein
namespace: uberon
xref: FMA:15395
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0001159 ! sigmoid colon
relationship: drains UBERON:0001159 ! sigmoid colon
relationship: part_of RO:0002577 ! system
relationship: tributary_of UBERON:0001215 {source="FMA"} ! inferior mesenteric vein

[Term]
id: UBERON:0039261
name: pancreatic artery
namespace: uberon
xref: FMA:70471
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0001264 ! pancreas
relationship: connecting_branch_of UBERON:0001194 ! splenic artery
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0001264 ! pancreas

[Term]
id: UBERON:0039355
name: urethral artery
namespace: uberon
synonym: "arteria urethralis" EXACT OMO:0003011 [A12.2.15.042]
xref: FMA:20903
is_a: UBERON:0001637 ! artery
intersection_of: UBERON:0001637 ! artery
intersection_of: supplies UBERON:0000057 ! urethra
relationship: part_of RO:0002577 ! system
relationship: supplies UBERON:0000057 ! urethra

[Term]
id: UBERON:0039377
name: urethral vein
namespace: uberon
def: "A vein that drains the urethra." [UBERON:cjm]
xref: FMA:21270
is_a: UBERON:0001638 ! vein
intersection_of: UBERON:0001638 ! vein
intersection_of: drains UBERON:0000057 ! urethra
relationship: drains UBERON:0000057 ! urethra
relationship: part_of RO:0002577 ! system
relationship: tributary_of UBERON:0018252 {source="FMA"} ! internal pudendal vein

[Term]
id: UBERON:0039856
name: right ovarian vein
namespace: uberon
def: "Ovarian vein, each instance of which is a tributary  of some inferior vena cava that drains the right pampiniform plexus of some broad ligament." [FMA:14342]
xref: FMA:14342
is_a: UBERON:0001145 {source="FMA"} ! ovarian vein
intersection_of: UBERON:0001145 ! ovarian vein
intersection_of: drains UBERON:0002118 ! right ovary
relationship: drains UBERON:0002118 ! right ovary
relationship: tributary_of UBERON:0001072 {source="FMA"} ! posterior vena cava

[Term]
id: UBERON:0039857
name: left ovarian vein
namespace: uberon
def: "Ovarian vein, each instance of which is a tributary  of some left renal vein that drains the left pampiniform plexus of some broad ligament." [FMA:14347]
xref: FMA:14347
is_a: UBERON:0001145 {source="FMA"} ! ovarian vein
intersection_of: UBERON:0001145 ! ovarian vein
intersection_of: drains UBERON:0002119 ! left ovary
relationship: drains UBERON:0002119 ! left ovary

[Term]
id: UBERON:1000021
name: skin of face
namespace: uberon
def: "A zone of skin that is part of the face." [https://github.com/obophenotype/uberon/issues/34, UBERON:EJS]
subset: pheno_slim
subset: phenotype_rcn
synonym: "face skin" EXACT [EMAPA:36657, FMA:24758]
synonym: "facial skin" RELATED []
xref: EMAPA:36657
xref: FMA:24758
xref: NCIT:C33561
xref: SCTID:361703006
xref: UMLS:C0222084 {source="ncithesaurus:Skin_of_the_Face"}
is_a: UBERON:0001084 ! skin of head
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0001456 ! face
relationship: part_of UBERON:0001456 ! face
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall
property_value: http://purl.org/dc/elements/1.1/contributor https://github.com/seger
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-9611-1279
creation_date: 2012-02-05T05:23:01Z

[Term]
id: UBERON:1000024
name: parenchyma of spleen
namespace: uberon
def: "A parenchyma that is part of a spleen." [OBOL:automatic]
synonym: "splenic parenchyma" EXACT [FMA:16029]
xref: FMA:16029
is_a: UBERON:0000353 ! parenchyma
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000353 ! parenchyma
intersection_of: part_of UBERON:0002106 ! spleen
relationship: part_of UBERON:0002106 ! spleen

[Term]
id: UBERON:1100000
name: digestive tract junction
namespace: uberon
def: "An anatomical junction between two parts of the digestive tract." [https://orcid.org/0000-0002-7073-9172]
is_a: UBERON:0007651 ! anatomical junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0004921 ! subdivision of digestive tract
relationship: connects UBERON:0004921 ! subdivision of digestive tract
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-7073-9172
creation_date: 2021-02-05T11:19:31Z

[Term]
id: UBERON:2001073
name: axial vasculature
namespace: uberon
xref: ZFA:0001073
is_a: UBERON:0002049 ! vasculature
property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"}

[Term]
id: UBERON:2001457
name: postcranial axial cartilage
namespace: uberon
def: "Cartilage which is part of the axial skeleton." [ZFIN:curator]
xref: ZFA:0001457
is_a: UBERON:0007844 ! cartilage element
intersection_of: UBERON:0007844 ! cartilage element
intersection_of: part_of UBERON:0002090 ! postcranial axial skeleton
relationship: part_of UBERON:0002090 ! postcranial axial skeleton
property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"}

[Term]
id: UBERON:2005260
name: fenestrated capillary
namespace: uberon
def: "Capillary that has pores in the endothelial cells (60-80 nm in diameter) that are spanned by a diaphragm of radially oriented fibrils and allow small molecules and limited amounts of protein to diffuse." [Wikipedia:Capillary#Types, Wikipedia:Fenestra_(histology)]
synonym: "fenestrated blood vessel endothelium" BROAD [ZFA:0005260]
synonym: "fenestrated capillary vessel" EXACT [FMA:63196]
xref: FMA:63196
xref: NCIT:C32595
xref: TAO:0005260
xref: UMLS:C1179615 {source="ncithesaurus:Fenestrated_Capillary"}
xref: Wikipedia:Capillary#Types
xref: ZFA:0005260
is_a: UBERON:0001982 {source="FMA"} ! capillary
is_a: UBERON:0004638 {source="ZFA"} ! blood vessel endothelium
property_value: editor_note "the ZFA class from which this was derived is not explicitly classified as a capillary - need to verify for taxon histology differences" xsd:string
property_value: UBPROP:0000001 "Blood vessel endothelium that has pores that allow passage small molecules and proteins[ZFA]." xsd:string

[Term]
id: UBERON:2007013
name: preplacodal ectoderm
namespace: uberon
def: "Non neural ectoderm that surrounds the presumptive neural plate and gives rise to neurogenic placodes." [ZFIN:curator]
xref: ZFA:0007013
is_a: UBERON:0005497 ! non-neural ectoderm
property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"}

[Term]
id: UBERON:3000961
name: external integument structure
namespace: uberon
def: "Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument." [AAO:EJS]
comment: Not clear how this differs from parent class. See https://github.com/obophenotype/uberon/issues/1305
is_a: UBERON:0003102 ! surface structure
intersection_of: UBERON:0003102 ! surface structure
intersection_of: part_of UBERON:0002199 ! integument
relationship: part_of UBERON:0002199 ! integument
property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"}

[Term]
id: UBERON:3000972
name: head external integument structure
namespace: uberon
def: "Dermal, epidermal, glandular and pigment structures of the external head integument." [AAO:EJS]
is_a: UBERON:3000961 ! external integument structure
intersection_of: UBERON:3000961 ! external integument structure
intersection_of: part_of UBERON:0000033 ! head
relationship: part_of UBERON:0000033 ! head
property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"}

[Term]
id: UBERON:3000977
name: body external integument structure
namespace: uberon
def: "Dermal, epidermal, glandular and pigment structures of the body integument." [AAO:EJS]
is_a: UBERON:3000961 ! external integument structure
intersection_of: UBERON:3000961 ! external integument structure
intersection_of: part_of UBERON:0002100 ! trunk
relationship: part_of UBERON:0002100 ! trunk
property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"}

[Term]
id: UBERON:3000982
name: tail external integument structure
namespace: uberon
def: "Dermal, epidermal, glandular and pigment structures of the tail integument." [AAO:EJS]
is_a: UBERON:3000961 ! external integument structure
intersection_of: UBERON:3000961 ! external integument structure
intersection_of: part_of UBERON:0007812 ! post-anal tail
relationship: part_of UBERON:0007812 ! post-anal tail
property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"}

[Term]
id: UBERON:3010200
name: vasculature of respiratory integument
namespace: uberon
def: "Blood vessels in respiratory skin." [AAO:EJS]
is_a: UBERON:0003504 ! respiratory system blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0001004 ! respiratory system
intersection_of: part_of UBERON:0002199 ! integument
relationship: part_of UBERON:0002199 ! integument
property_value: editor_note "Modified from the original AAO source" xsd:string
property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"}

[Term]
id: UBERON:4200230
name: surface of bone
namespace: uberon
def: "An anatomical surface that is part of a bone." [PHENOSCAPE]
synonym: "bone surface" EXACT []
is_a: UBERON:0006984 ! anatomical surface
intersection_of: UBERON:0006984 ! anatomical surface
intersection_of: part_of UBERON:0001474 ! bone element
relationship: part_of UBERON:0001474 ! bone element

[Term]
id: UBERON:6000002
name: arthropod tagma
namespace: uberon
def: "One of the main divisions of the whole organism of arthropods formed from groups of segments." [doi:10.1016/B978-0-12-385026-3.00024-3]
comment: Strictly speaking the term "tagma" cam be used for any metameric organism, however we follow the common usage which is to restrict the term to arthropods.
xref: FBbt:00000002 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0011676 ! subdivision of organism along main body axis
relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda
property_value: RO:0002161 NCBITaxon:7742

[Term]
id: UBERON:6000004
name: panarthropod head
namespace: uberon
xref: FBbt:00000004 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0000033 ! head
intersection_of: UBERON:0000033 ! head
intersection_of: part_of NCBITaxon:88770 ! Panarthropoda
relationship: part_of NCBITaxon:88770 ! Panarthropoda

[Term]
id: UBERON:6000137
name: embryonic tagma
namespace: uberon
def: "Any tagma (UBERON:6000002) that is part of some embryo (UBERON:6000052)." [FBC:auto_generated_definition]
xref: FBbt:00000137 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:6000002 ! arthropod tagma
intersection_of: UBERON:6000002 ! arthropod tagma
intersection_of: part_of UBERON:0000922 ! embryo
relationship: part_of UBERON:0000922 ! embryo

[Term]
id: UBERON:6001728
name: insect larval tagma
namespace: uberon
def: "Any tagma (UBERON:6000002) that is part of some larva (UBERON:6001727)." [FBC:auto_generated_definition]
xref: FBbt:00001728 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:6000002 ! arthropod tagma
intersection_of: UBERON:6000002 ! arthropod tagma
intersection_of: part_of UBERON:0002548 ! larva
relationship: part_of UBERON:0002548 ! larva

[Term]
id: UBERON:6001730
name: insect larval head
namespace: uberon
def: "Any head that is part of some larva." [FBC:auto_generated_definition]
xref: FBbt:00001730 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0000033 ! head
intersection_of: UBERON:0000033 ! head
intersection_of: only_in_taxon NCBITaxon:50557 ! Insecta
intersection_of: part_of UBERON:0002548 ! larva
relationship: only_in_taxon NCBITaxon:50557 ! Insecta
relationship: part_of UBERON:0002548 ! larva

[Term]
id: UBERON:6002639
name: insect larval sense organ
namespace: uberon
def: "Any sense organ that is part of some larva." [FBC:auto_generated_definition]
synonym: "larval sense organ" EXACT []
xref: FBbt:00002639 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0000020 ! sense organ
intersection_of: UBERON:0000020 ! sense organ
intersection_of: only_in_taxon NCBITaxon:50557 ! Insecta
intersection_of: part_of UBERON:0002548 ! larva
relationship: only_in_taxon NCBITaxon:50557 ! Insecta
relationship: part_of UBERON:0002548 ! larva

[Term]
id: UBERON:6003005
name: insect adult tagma
namespace: uberon
def: "Any tagma (UBERON:6000002) that is part of some adult (UBERON:6003004)." [FBC:auto_generated_definition]
xref: FBbt:00003005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:6000002 ! arthropod tagma
intersection_of: UBERON:6000002 ! arthropod tagma
intersection_of: part_of UBERON:0007023 ! adult organism
relationship: part_of UBERON:0007023 ! adult organism

[Term]
id: UBERON:6003007
name: insect adult head
namespace: uberon
def: "Head of the adult organism." [FBC:SPR]
xref: FBbt:00003007 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:6000004 ! panarthropod head
is_a: UBERON:6003005 ! insect adult tagma
intersection_of: UBERON:0000033 ! head
intersection_of: part_of NCBITaxon:50557 ! Insecta
intersection_of: part_of UBERON:0007023 ! adult organism
relationship: part_of NCBITaxon:50557 ! Insecta

[Term]
id: UBERON:6007240
name: insect embryonic/larval sensillum
namespace: uberon
def: "Any sensillum (UBERON:6007152) that is part of some larva (UBERON:6001727)." [FBC:auto_generated_definition]
synonym: "larval sensillum" EXACT []
xref: FBbt:00007240 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0002536 ! arthropod sensillum
is_a: UBERON:6002639 ! insect larval sense organ
intersection_of: UBERON:0002536 ! arthropod sensillum
intersection_of: part_of UBERON:0002548 ! larva

[Term]
id: UBERON:6007242
name: insect embryonic/larval head sensillum
namespace: uberon
def: "Any sensillum (UBERON:6007152) that is part of some larval head (UBERON:6001730)." [FBC:auto_generated_definition]
synonym: "larval head sensillum" NARROW []
xref: FBbt:00007242 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0000963 ! head sensillum
is_a: UBERON:6007240 ! insect embryonic/larval sensillum
is_a: UBERON:6007280 ! insect embryonic/larval head sense organ
intersection_of: UBERON:0002536 ! arthropod sensillum
intersection_of: part_of UBERON:6001730 ! insect larval head

[Term]
id: UBERON:6007280
name: insect embryonic/larval head sense organ
namespace: uberon
def: "Any sense organ (UBERON:6005155) that is part of some larval head (UBERON:6001730)." [FBC:auto_generated_definition]
synonym: "larval head sense organ" EXACT []
xref: FBbt:00007280 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:6002639 ! insect larval sense organ
intersection_of: UBERON:0000020 ! sense organ
intersection_of: part_of UBERON:6001730 ! insect larval head
relationship: part_of UBERON:6001730 ! insect larval head

[Term]
id: UBERON:6007284
name: insect region of integument
namespace: uberon
def: "A region of cuticle and its underlying epidermis." [FBC:DOS]
xref: FBbt:00007284 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:0011216 ! organ system subdivision
relationship: only_in_taxon NCBITaxon:50557 ! Insecta
relationship: part_of UBERON:0002416 ! integumental system

[Term]
id: UBERON:6007289
name: insect tagmatic subdivision of integument
namespace: uberon
def: "Region of integument of a tagma.\nhttp://flybase.org/cgi-bin/fbcvq.html?query=FBbt:00007289" []
xref: FBbt:00007289 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"}
is_a: UBERON:6007284 ! insect region of integument

[Term]
id: UBERON:8000006
name: left side of back
namespace: uberon
def: "Left part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane." [https://microbiomedb.org/]
is_a: UBERON:0001137 ! dorsum
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0001137 ! dorsum
intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism
relationship: in_left_side_of UBERON:0000468 ! multicellular organism
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: UBERON:8000007
name: right side of back
namespace: uberon
def: "Right part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane." [https://microbiomedb.org/]
is_a: UBERON:0001137 ! dorsum
is_a: UBERON:0015212 ! lateral structure
intersection_of: UBERON:0001137 ! dorsum
intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism
relationship: in_right_side_of UBERON:0000468 ! multicellular organism
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: UBERON:8000009
name: Purkinje fiber network
namespace: uberon
def: "A collection of Purkinje fibers that receives signals from the right and left bundle branches and innervates the ventricular cardiac muscle. The Purkinje fiber network creates synchronized contractions of the heart ventricles." [PMID:26786210]
synonym: "Purkinje fibre network" EXACT [PMID:26786210]
is_a: UBERON:0010131 {source="https://github.com/obophenotype/uberon/issues/1785", source="https://orcid.org/0000-0001-5208-3432", source="https://orcid.org/0000-0002-9791-0064"} ! conducting tissue of heart
is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle
relationship: has_part UBERON:0002354 {source="https://github.com/obophenotype/uberon/issues/1785", source="https://orcid.org/0000-0001-5208-3432", source="https://orcid.org/0000-0002-9791-0064"} ! cardiac Purkinje fiber
relationship: part_of UBERON:0004146 {source="https://github.com/obophenotype/uberon/issues/1785", source="https://orcid.org/0000-0001-5208-3432", source="https://orcid.org/0000-0002-9791-0064"} ! His-Purkinje system
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-5208-3432

[Term]
id: UBERON:8400021
name: liver serosa
namespace: uberon
def: "Hepatic serous coat; peritoneal covering of the liver, enclosing almost all except for a triangular area on its posterior surface (the 'bare area of the liver') and a smaller area where the liver and gallbladder are in direct contact." [https://medical-dictionary.thefreedictionary.com/serosa+of+liver, https://orcid.org/0000-0002-0449-2730]
synonym: "serosa of liver" EXACT [FMA:15811]
synonym: "tunica serosa hepatis" EXACT OMO:0003011 [https://medical-dictionary.thefreedictionary.com/serosa+of+liver]
is_a: UBERON:0000042 ! serous membrane
is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure
intersection_of: UBERON:0000042 ! serous membrane
intersection_of: part_of UBERON:0002107 ! liver
relationship: part_of UBERON:0002107 ! liver
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-2034-601X

[Term]
id: UBERON:8400023
name: liver subserosa
namespace: uberon
def: "Subserosal tissue of liver. A zone of areolar connective tissue lying beneath the serous coat of the liver and distinguished with difficulty from the fibrous capsule of Glisson." [FMA:15812, https://medical-dictionary.thefreedictionary.com/subserosa+of+liver, https://orcid.org/0000-0002-0449-2730]
synonym: "hepatic subserosa" EXACT []
synonym: "subserosal tissue of liver" EXACT []
synonym: "subserous layer of liver" EXACT []
synonym: "tela subserosa (hepar)" EXACT [FMA:15821]
synonym: "tela subserosa hepatis" EXACT [https://medical-dictionary.thefreedictionary.com/subserosa+of+liver]
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0012375 ! subserosa
intersection_of: UBERON:0012375 ! subserosa
intersection_of: part_of UBERON:0002107 ! liver
relationship: part_of UBERON:0002107 ! liver
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-2034-601X

[Term]
id: UBERON:8410001
name: small intestine venule
namespace: uberon
def: "Venule of villus of small intestine." [https://orcid.org/0000-0003-4183-8865]
subset: location_grouping
synonym: "venule of small intestine" EXACT []
is_a: UBERON:0001979 ! venule
intersection_of: UBERON:0001979 ! venule
intersection_of: part_of UBERON:0001213 ! intestinal villus
relationship: part_of UBERON:0001213 ! intestinal villus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: UBERON:8410004
name: small intestine arteriole
namespace: uberon
def: "Arteriole of villus of small intestine." [http://orcid.org/0000-0003-4183-8865]
subset: location_grouping
synonym: "arteriole of small intestine" EXACT []
synonym: "arteriole of villus of small intestine" EXACT []
synonym: "small intestine villus arteriole" EXACT []
is_a: UBERON:0001980 ! arteriole
intersection_of: UBERON:0001980 ! arteriole
intersection_of: part_of UBERON:0001213 ! intestinal villus
relationship: part_of UBERON:0001213 ! intestinal villus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: UBERON:8410008
name: venule of anorectum
namespace: uberon
def: "A venule that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876]
synonym: "anorectum venule" EXACT []
is_a: UBERON:0001979 ! venule
intersection_of: UBERON:0001979 ! venule
intersection_of: part_of UBERON:8410050 ! anorectum
relationship: part_of UBERON:8410050 ! anorectum
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: UBERON:8410009
name: arteriole of anorectum
namespace: uberon
def: "An arteriole that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876]
synonym: "anorectum arteriole" EXACT []
is_a: UBERON:0001980 ! arteriole
intersection_of: UBERON:0001980 ! arteriole
intersection_of: part_of UBERON:8410050 ! anorectum
relationship: part_of UBERON:8410050 ! anorectum
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: UBERON:8410015
name: arteriole of colon
namespace: uberon
def: "An arteriole located in the colon." [http://orcid.org/0000-0003-3440-1876, http://orcid.org/0000-0003-4183-8865]
is_a: UBERON:0001980 ! arteriole
intersection_of: UBERON:0001980 ! arteriole
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: UBERON:8410024
name: intestinal junction
namespace: uberon
def: "An anatomical junction between two parts of the intestine." [https://orcid.org/0000-0002-7073-9172]
synonym: "junction of intestine" EXACT []
is_a: UBERON:1100000 ! digestive tract junction
intersection_of: UBERON:0007651 ! anatomical junction
intersection_of: connects UBERON:0004921 ! subdivision of digestive tract
intersection_of: part_of UBERON:0000160 ! intestine
relationship: part_of UBERON:0000160 ! intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: UBERON:8410048
name: venule of colon
namespace: uberon
def: "A venule located in the colon." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865]
is_a: UBERON:0001979 ! venule
intersection_of: UBERON:0001979 ! venule
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: UBERON:8410050
name: anorectum
namespace: uberon
def: "A subdivision of the digestive tract in humans that includes the rectum, the anal canal and the anus." [DOI:10.1007/978-3-319-26938-2_8, DOI:10.1148/rg.2015150037, http://orcid.org/0000-0002-6826-8770, http://orcid.org/0000-0003-3440-1876, PMID:29742860]
synonym: "anorectal canal" NARROW []
is_a: UBERON:0004921 ! subdivision of digestive tract
intersection_of: UBERON:0004921 ! subdivision of digestive tract
intersection_of: has_part UBERON:0000159 ! anal canal
intersection_of: has_part UBERON:0001052 ! rectum
intersection_of: has_part UBERON:0001245 ! anus
relationship: has_part UBERON:0000159 ! anal canal
relationship: has_part UBERON:0001052 ! rectum
relationship: has_part UBERON:0001245 ! anus
relationship: part_of UBERON:0000059 ! large intestine
property_value: editor_note "The anatomy, pathology and medical community considers the anus to be part of the large intestine, and supports the use of 'anorectum' to include rectum, anal canal and anus. Although a few resources seem to only include the distal part of the rectum in 'anorectum', this UBERON grouping term is meant to refer more broadly to the whole of rectum." xsd:string
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: RO:0002175 NCBITaxon:9606
property_value: UBPROP:0000007 "anorectal" xsd:string

[Term]
id: UBERON:8410056
name: capillary of anorectum
namespace: uberon
def: "A capillary that is part of the anorectum." [http://orcid.org/0000-0003-3440-1876]
synonym: "blood vessel capillary of anorectum" EXACT []
is_a: UBERON:0001982 ! capillary
intersection_of: UBERON:0001982 ! capillary
intersection_of: part_of UBERON:8410050 ! anorectum
relationship: part_of UBERON:8410050 ! anorectum
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: UBERON:8410057
name: capillary of colon
namespace: uberon
def: "A capillary that is part of the colon." [http://orcid.org/0000-0003-3440-1876]
synonym: "blood vessel capillary of colon" EXACT []
is_a: UBERON:0001982 ! capillary
intersection_of: UBERON:0001982 ! capillary
intersection_of: part_of UBERON:0001155 ! colon
relationship: part_of UBERON:0001155 ! colon
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621

[Term]
id: UBERON:8410068
name: capillary of small intestine
namespace: uberon
def: "A capillary that is part of a small intestine." [http://orcid.org/0000-0003-3440-1876]
subset: location_grouping
synonym: "blood vessel capillary of small intestine" EXACT []
synonym: "small intestine capillary" EXACT []
is_a: UBERON:0001982 ! capillary
intersection_of: UBERON:0001982 ! capillary
intersection_of: part_of UBERON:0002108 ! small intestine
relationship: part_of UBERON:0002108 ! small intestine
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: http://purl.org/dc/terms/date "2021-12-21T15:14:31Z" xsd:dateTime

[Term]
id: UBERON:8410077
name: airway submucosal gland
namespace: uberon
def: "A submucosal gland found in a respiratory tract." [http://orcid.org/0000-0003-3440-1876, http://orcid.org/0000-0003-4183-8865]
synonym: "respiratory tract submucosal gland" EXACT []
synonym: "submucosal gland of respiratory tract" EXACT []
xref: EFO:0010666
is_a: UBERON:0004119 ! endoderm-derived structure
is_a: UBERON:0011148 ! submucosal gland
is_a: UBERON:0036225 ! respiratory system gland
intersection_of: UBERON:0011148 ! submucosal gland
intersection_of: part_of UBERON:0000065 ! respiratory tract
relationship: part_of UBERON:0000065 ! respiratory tract
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2825-0621
property_value: http://purl.org/dc/terms/date "2022-03-24T14:21:59Z" xsd:dateTime

[Term]
id: UBERON:8410081
name: blood microvessel
namespace: uberon
def: "Any of the smallest blood vessels where blood circulates within organ tissues. Microvessels include terminal arterioles, metarterioles, capillaries, and venules (but exclude lymphatic capillaries). Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries through venules into veins." [http://orcid.org/0000-0002-7073-9172, Wikipedia:Microcirculation]
synonym: "microvasculature" BROAD []
synonym: "microvessel" BROAD []
is_a: UBERON:0001981 ! blood vessel
is_a: UBERON:0010523 ! microcirculatory vessel
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/2186" xsd:string
property_value: UBPROP:0000007 "microvascular" xsd:string
created_by: http://orcid.org/0000-0002-2825-0621

[Term]
id: UBERON:8440015
name: noradrenergic cell groups
namespace: uberon
def: "Collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to contain the neurotransmitter norepinephrine (noradrenalin)." [WikipediaVersioned:Noradrenergic_cell_groups&oldid=965992184]
is_a: UBERON:0002616 ! regional part of brain
relationship: composed_primarily_of CL:0000459 ! noradrenergic cell

[Term]
id: UBERON:8450002
name: excretory system
namespace: uberon
def: "An anatomical system that eliminates waste products that arise as a result of metabolic activity." [GO:0007588]
subset: human_reference_atlas
xref: BTO:0006338 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"}
is_a: UBERON:0000467 ! anatomical system
intersection_of: UBERON:0000467 ! anatomical system
intersection_of: capable_of GO:0046903 ! secretion
relationship: capable_of GO:0046903 ! secretion
property_value: RO:0002175 NCBITaxon:9606
created_by: http://orcid.org/0000-0002-6095-8718
creation_date: 2022-05-25T18:21:29Z

[Term]
id: UBERON:8470000
name: placental blood
namespace: uberon
def: "Blood located in the placenta." [http://orcid.org/0000-0001-6595-0902, https://www.ncbi.nlm.nih.gov/books/NBK53254/]
is_a: UBERON:0000178 ! blood
intersection_of: UBERON:0000178 ! blood
intersection_of: located_in UBERON:0001987 ! placenta
relationship: located_in UBERON:0001987 ! placenta
property_value: http://purl.org/dc/terms/date "2022-04-04T11:06:09Z" xsd:dateTime

[Term]
id: UBERON:8480000
name: iliac vein smooth muscle tissue
namespace: uberon
def: "A portion of smooth muscle tissue that is part of an iliac vein." [https://orcid.org/0000-0002-0819-0473]
is_a: UBERON:0004696 ! venous system smooth muscle
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0005610 ! iliac vein
relationship: part_of UBERON:0005610 ! iliac vein
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-06-17T14:34:50Z" xsd:dateTime

[Term]
id: UBERON:8480001
name: capillary of brain
namespace: uberon
def: "A capillary that is part of the brain." [https://orcid.org/0000-0002-0819-0473]
is_a: UBERON:0001982 ! capillary
is_a: UBERON:0003499 ! brain blood vessel
intersection_of: UBERON:0001982 ! capillary
intersection_of: part_of UBERON:0000955 ! brain
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-06-24T09:28:31Z" xsd:dateTime

[Term]
id: UBERON:8480002
name: thoracic aorta smooth muscle tissue
namespace: uberon
def: "A portion of smooth muscle tissue that is part of the thoracic aorta." [https://orcid.org/0000-0002-0819-0473]
is_a: UBERON:0004178 ! aorta smooth muscle tissue
intersection_of: UBERON:0001135 ! smooth muscle tissue
intersection_of: part_of UBERON:0001515 ! thoracic aorta
relationship: part_of UBERON:0001515 ! thoracic aorta
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-06-24T09:30:54Z" xsd:dateTime

[Term]
id: UBERON:8480004
name: iliac vein endothelium
namespace: uberon
def: "An endothelium that is part of an iliac vein." [https://orcid.org/0000-0002-0819-0473]
is_a: UBERON:0001919 ! endothelium of vein
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:0005610 ! iliac vein
relationship: part_of UBERON:0005610 ! iliac vein
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-06-24T09:33:18Z" xsd:dateTime

[Term]
id: UBERON:8480005
name: placental artery endothelium
namespace: uberon
def: "An endothelium that is part of the placental artery." [https://orcid.org/0000-0002-0819-0473]
is_a: UBERON:0001917 ! endothelium of artery
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0005292 ! extraembryonic tissue
intersection_of: UBERON:0001986 ! endothelium
intersection_of: part_of UBERON:8480007 ! placental artery
relationship: part_of UBERON:8480007 ! placental artery
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-06-24T09:34:25Z" xsd:dateTime

[Term]
id: UBERON:8480007
name: placental artery
namespace: uberon
def: "An artery that is part of the placenta." [https://orcid.org/0000-0002-0819-0473]
is_a: UBERON:0001637 ! artery
is_a: UBERON:0022358 ! placenta blood vessel
intersection_of: UBERON:0001637 ! artery
intersection_of: part_of UBERON:0001987 ! placenta
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-06-24T11:25:24Z" xsd:dateTime

[Term]
id: UBERON:8480008
name: placental vein
namespace: uberon
def: "A vein that is part of the placenta." [https://orcid.org/0000-0002-0819-0473]
is_a: UBERON:0001638 ! vein
is_a: UBERON:0022358 ! placenta blood vessel
intersection_of: UBERON:0001638 ! vein
intersection_of: part_of UBERON:0001987 ! placenta
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-06-27T09:30:52Z" xsd:dateTime

[Term]
id: UBERON:8480025
name: skin of clavicle region
namespace: uberon
def: "A zone of skin that is above the clavicle zone in the pectoral girdle region." [https://orcid.org/0000-0002-0819-0473]
is_a: UBERON:0000014 ! zone of skin
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0001421 ! pectoral girdle region
relationship: part_of UBERON:0001421 ! pectoral girdle region
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-08-29T14:17:12Z" xsd:dateTime

[Term]
id: UBERON:8480026
name: skin of iliac crest region
namespace: uberon
def: "A zone of skin that is above the iliac crest in the pelvic girdle bone/zone." [https://orcid.org/0000-0002-0819-0473]
synonym: "skin of posterior iliac crest region" BROAD []
is_a: UBERON:0001415 ! skin of pelvis
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0007830 ! pelvic girdle bone/zone
relationship: part_of UBERON:0007830 ! pelvic girdle bone/zone
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-08-29T14:19:16Z" xsd:dateTime

[Term]
id: UBERON:8480029
name: skin of external genitalia
namespace: uberon
def: "A zone of skin that is part of the external genitalia." [https://orcid.org/0000-0002-0819-0473]
is_a: UBERON:0000014 ! zone of skin
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0004176 ! external genitalia
relationship: part_of UBERON:0004176 ! external genitalia
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-08-30T06:55:06Z" xsd:dateTime

[Term]
id: UBERON:8480037
name: subserosa of uterine tube
namespace: uberon
def: "Subserosa that is part of the uterine tube. It contains loose connective tissue, blood vessels and lymphatic tissue." [ISBN:9783662026762, PMID:30095490]
synonym: "subserosa of fallopian tube" EXACT [PMID:30095490]
synonym: "subserosa of oviduct" EXACT [PMID:34440264]
is_a: UBERON:0004120 ! mesoderm-derived structure
is_a: UBERON:0005156 ! reproductive structure
is_a: UBERON:0012375 ! subserosa
intersection_of: UBERON:0012375 ! subserosa
intersection_of: part_of UBERON:0003889 ! fallopian tube
relationship: part_of UBERON:0003889 ! fallopian tube
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2022-10-21T08:55:11Z" xsd:dateTime

[Term]
id: UBERON:8480074
name: skin of gonad
namespace: uberon
def: "A zone of skin part of some gonad." [https://orcid.org/0000-0002-0819-0473]
is_a: UBERON:0000014 ! zone of skin
is_a: UBERON:0005156 ! reproductive structure
intersection_of: UBERON:0000014 ! zone of skin
intersection_of: part_of UBERON:0000991 ! gonad
relationship: part_of UBERON:0000991 ! gonad
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-0819-0473
property_value: http://purl.org/dc/terms/date "2023-08-29T10:24:24Z" xsd:dateTime

[Term]
id: UBERON:8600004
name: visceral muscle tissue
namespace: uberon
def: "A muscle tissue that is associated with soft internal organs (viscera)." [BTO:0002780, CLAO:0001295]
comment: It is quite common to refer to visceral muscles as smooth muscles, by analogy with vertebrates; however, most visceral muscles in arthropods are actually striated. {xref="https://en.wikipedia.org/wiki/Smooth_muscle", xref="FBbt:00005070", comment="PMID:8720463"}
synonym: "visceral muscle" EXACT [] {comment="BTO:0002780"}
is_a: UBERON:0002385 ! muscle tissue
relationship: composed_primarily_of CL:0008007 ! visceral muscle cell
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/date "2023-02-16T10:17:46Z" xsd:dateTime

[Term]
id: UBERON:8600006
name: visceral striated muscle tissue
namespace: uberon
def: "A striated muscle tissue that is associated with soft internal organs (viscera)." [https://pressbooks.pub/rbtallitsch/chapter/chapter-6-muscle-tissue/, PMID:8720463]
synonym: "striated visceral muscle tissue" EXACT []
is_a: UBERON:0002036 ! striated muscle tissue
is_a: UBERON:8600004 ! visceral muscle tissue
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/date "2023-02-16T10:34:43Z" xsd:dateTime

[Term]
id: UBERON:8600012
name: submucosal gland acinus
namespace: uberon
def: "A spherical or tubular structure in a submucosal gland that produces and secretes mucus and other substances into the ducts leading to the surface epithelium." [PMID:17394068, PMID:17707699, PMID:25648514, PMID:30864819]
subset: human_reference_atlas
is_a: UBERON:0014717 ! mucous acinus
intersection_of: UBERON:0009842 ! glandular acinus
intersection_of: part_of UBERON:0011148 ! submucosal gland
relationship: part_of UBERON:0011148 ! submucosal gland
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/date "2023-05-02T08:57:27Z" xsd:dateTime
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:8600017
name: bronchopulmonary segment
namespace: uberon
def: "A discrete anatomical unit of the lung that is composed of a segmental bronchus and the lung tissue supplied by that bronchus. A bronchopulmonary segment exhibits a pyramidal shape, with its apex pointing towards the center of the lung and its base toward the pleural surface." [doi:10.1016/j.mpaic.2008.09.022, FMA:7312, PMID:18271171, PMID:33620799]
comment: A bronchopulmonary segment is surrounded by connective tissue septa, which are continuous with the pleural surface and prevent air collateralization between segments somewhat. In humans, the right lung has ten bronchopulmonary segments and eight or nine bronchopulmonary segments in the left lung. {xref="doi:10.1016/j.mpaic.2008.09.022", xref="PMID:18271171"}
subset: human_reference_atlas
synonym: "lung segment" EXACT [PMID:33620799]
is_a: UBERON:0000063 ! organ subunit
is_a: UBERON:0004119 ! endoderm-derived structure
relationship: contributes_to_morphology_of UBERON:0000101 ! lobe of lung
relationship: part_of UBERON:0000101 ! lobe of lung
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-9185-3994
property_value: http://purl.org/dc/terms/date "2023-07-20T12:43:29Z" xsd:dateTime
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:8600021
name: chorionic plate blood vessel
namespace: uberon
def: "A blood vessel that is part of the chorionic plate." [https://www.ncbi.nlm.nih.gov/books/NBK53254/]
subset: human_reference_atlas
is_a: UBERON:0022358 ! placenta blood vessel
intersection_of: UBERON:0001981 ! blood vessel
intersection_of: part_of UBERON:0004027 ! chorionic plate
relationship: part_of UBERON:0004027 ! chorionic plate
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/date "2023-09-14T09:09:36Z" xsd:dateTime
property_value: RO:0002175 NCBITaxon:9606

[Term]
id: UBERON:8600023
name: placental villous stroma
namespace: uberon
def: "A stroma that is part of a chorionic villus (placental villus). A placental villous stroma supports the fetal capillaries and villous trophoblast." [PMID:31512233]
synonym: "chorionic villous stroma" EXACT [PMID:12624135]
synonym: "CVS" RELATED OMO:0003000 [PMID:12624135]
is_a: UBERON:0003891 ! stroma
is_a: UBERON:0004120 ! mesoderm-derived structure
intersection_of: UBERON:0003891 ! stroma
intersection_of: part_of UBERON:0007106 ! chorionic villus
relationship: part_of UBERON:0007106 ! chorionic villus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-7655-4833
property_value: http://purl.org/dc/terms/date "2023-07-04T10:46:17Z" xsd:dateTime

[Term]
id: UBERON:8600024
name: pulmonary venule
namespace: uberon
def: "A venule that is part of a lung and drains oxygenated blood from pulmonary capillaries. A pulmonary venule merges into a pulmonary vein branch that runs in the pulmonary interlobular septa." [PMID:22283705, PMID:30247823]
is_a: UBERON:0003494 ! respiratory system venule
is_a: UBERON:0003512 ! lung blood vessel
is_a: UBERON:0005194 ! thoracic vein
intersection_of: UBERON:0001979 ! venule
intersection_of: part_of UBERON:0002048 ! lung
relationship: connected_to UBERON:0002016 ! pulmonary vein
relationship: drains UBERON:0016405 ! pulmonary capillary
relationship: part_of RO:0002577 ! system
relationship: part_of UBERON:0013127 ! pulmonary venous system
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/date "2023-10-24T11:26:27Z" xsd:dateTime

[Term]
id: UBERON:8600038
name: placental disc
namespace: uberon
def: "A disc-shaped structure that is part of the placenta. A placental disc supports fetal development through the exchange of nutrients between maternal and fetal bloodstreams. The placental disc is structured to keep the blood streams separate, while maximizing surface area for the transport of nutrients between them, to maintain an immunological barrier." [PMID:35496035]
synonym: "placental disk" EXACT [PMID:30133439]
is_a: UBERON:0004120 ! mesoderm-derived structure
relationship: part_of UBERON:0001987 ! placenta
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/date "2024-01-16T17:50:20Z" xsd:dateTime

[Term]
id: UBERON:8600039
name: chorionic villous mesenchyme
namespace: uberon
def: "A mesenchyme that is part of a chorionic villus." [doi:10.1007/978-3-030-84725-8]
is_a: UBERON:0002050 ! embryonic structure
is_a: UBERON:0003265 ! chorionic mesenchyme
is_a: UBERON:0010377 ! mesenchyme from somatopleure
intersection_of: UBERON:0003104 ! mesenchyme
intersection_of: part_of UBERON:0007106 ! chorionic villus
relationship: part_of UBERON:0007106 ! chorionic villus
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0001-6677-8489
property_value: http://purl.org/dc/terms/date "2024-01-16T18:13:12Z" xsd:dateTime

[Term]
id: http://flybase.org/reports/FBgn0034157
name: resilin (fruit fly)
namespace: gene
def: "A protein coding gene resilin in fruit fly." [PRO:DNx]
comment: Category=external.
is_a: SO:0001217 ! protein_coding_gene
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Typedef]
id: 2D_boundary_of
name: 2D boundary of
def: "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity" []
xref: RO:0002000
property_value: editor_note "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts." xsd:string
property_value: editor_note "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape." xsd:string
property_value: IAO:0000112 "the surface of my skin is a 2D boundary of my body" xsd:string
property_value: IAO:0000118 "2D_boundary_of" xsd:string
property_value: IAO:0000118 "boundary of" xsd:string
property_value: IAO:0000118 "is 2D boundary of" xsd:string
property_value: IAO:0000118 "is boundary of" xsd:string
property_value: IAO:0000118 "surface of" xsd:string
property_value: RO:0001900 RO:0001901
is_a: mereotopologically_related_to ! mereotopologically related to
inverse_of: has_boundary ! has 2D boundary

[Typedef]
id: AISM:0000011
name: lateral_to {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
def: "X lateral to y if x is further from the midsagittal plane than y." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
inverse_of: AISM:0000012 ! medial_to

[Typedef]
id: AISM:0000012
name: medial_to {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2020-10-27"}
def: "X medial to y if x is closer to the midsagittal plane than y." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}

[Typedef]
id: AISM:0000078
name: encircles {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
def: "Structure x encircles structure y if both x and y are regions of the 2D structure z, or 2D cross-sections of a 3D object z, and the boundary of y on z is exclusively continuous with x." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_transitive: true
is_a: continuous_with ! continuous with
inverse_of: AISM:0000079 ! encircled by

[Typedef]
id: AISM:0000079
name: encircled by {creation_date="2020-11-11", http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075"}
def: "Structure y is encircled by structure x if both x and y are regions of the 2D structure z, or 2D cross-sections of a 3D object z, and the boundary of y on z is exclusively continuous with y." [] {http://purl.org/dc/elements/1.1/contributor="imiko https://orcid.org/0000-0003-2938-9075", creation_date="2021-04-21"}
is_transitive: true
is_a: continuous_with ! continuous with

[Typedef]
id: AISM:0000404
name: has_unit {creation_date="2023-18-10", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}
def: "The object property of an object consisting of having a measurement unit." [] {creation_date="2023-18-10", http://purl.org/dc/elements/1.1/contributor="gmontanaro https://orcid.org/0000-0003-0836-1364"}

[Typedef]
id: AISM:0000519
name: encircles via conjunctiva
def: "Sclerite A encircles_via_conjunctiva sclerite B if A is encircled_via_conjuntiva X that encircles B." [] {http://purl.org/dc/elements/1.1/contributor="starasov https://orcid.org/0000-0001-5237-2330", creation_date="2021-05-31"}
domain: AISM:0000003 ! insect sclerite
range: AISM:0000003 ! insect sclerite
is_a: AISM:0000078 ! encircles

[Typedef]
id: AISM:0000538
name: encircled via conjunctiva
def: "Sclerite B is encircled_via_conjunctiva if sclerite A encircles_via_conjuntiva X sclerite B." [] {creation_date="2021-06-14", http://purl.org/dc/elements/1.1/contributor="jgiron https://orcid.org/0000-0002-0851-6883"}
domain: AISM:0000003 ! insect sclerite
range: AISM:0000003 ! insect sclerite
is_a: AISM:0000079 ! encircled by

[Typedef]
id: BSPO:0001102
name: parallel to
namespace: spatial
def: "x is parallel t y iff x and y are lines or planes which when extended indefinitely do not cross." [BSPO:curators]

[Typedef]
id: CL:4030045
name: lacks_part
expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y" []

[Typedef]
id: CL:4030046
name: lacks_plasma_membrane_part
expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)" []

[Typedef]
id: IAO:0000136
name: is about
def: "A (currently) primitive relation that relates an information artifact to an entity." []
property_value: editor_note "7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of \"mentions\" relation. Weaken the is_about relationship to be primitive. \n\nWe will try to build it back up by elaborating the various subproperties that are more precisely defined.\n\nSome currently missing phenomena that should be considered \"about\" are predications - \"The only person who knows the answer is sitting beside me\" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic." xsd:string
property_value: IAO:0000112 "This document is about information artifacts and their representations" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 "person:Alan Ruttenberg" xsd:string
property_value: IAO:0000119 "Smith, Ceusters, Ruttenberg, 2000 years of philosophy" xsd:string
domain: IAO:0000030 ! information content entity

[Typedef]
id: IAO:0000219
name: denotes
def: "A primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically" []
property_value: editor_note "2009-11-10 Alan Ruttenberg. Old definition said the following to emphasize the generic nature of this relation. We no longer have 'specifically denotes', which would have been primitive, so make this relation primitive.\ng denotes r =def \nr is a portion of reality\nthere is some c that is a concretization of g \nevery c that is a concretization of g specifically denotes r" xsd:string
property_value: IAO:0000112 "A person's name denotes the person. A variable name in a computer program denotes some piece of memory. Lexically equivalent strings can denote different things, for instance \"Alan\" can denote different people. In each case of use, there is a case of the denotation relation obtaining, between \"Alan\" and the person that is being named." xsd:string
property_value: IAO:0000117 "person:Alan Ruttenberg" xsd:string
property_value: IAO:0000119 "Conversations with Barry Smith, Werner Ceusters, Bjoern Peters, Michel Dumontier, Melanie Courtot, James Malone, Bill Hogan" xsd:string
domain: IAO:0000030 ! information content entity
range: BFO:0000001 ! entity
is_a: IAO:0000136 ! is about
inverse_of: IAO:0000235 ! denoted by

[Typedef]
id: IAO:0000235
name: denoted by
def: "inverse of the relation 'denotes'" []
property_value: IAO:0000117 "Person: Jie Zheng, Chris Stoeckert, Mike Conlon" xsd:string
property_value: IAO:0000233 https://github.com/information-artifact-ontology/IAO/issues/206
domain: BFO:0000001 ! entity
range: IAO:0000030 ! information content entity

[Typedef]
id: OBI:0000299
name: has_specified_output
def: "The inverse property of is_specified_output_of" []
property_value: IAO:0000111 "has_specified_output" xsd:string
property_value: IAO:0000111 "has_specified_output" xsd:string
property_value: IAO:0000114 IAO:0000122
property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string
property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string
property_value: IAO:0000117 "PERSON: Larry Hunter" xsd:string
property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string
property_value: IAO:0000412 http://purl.obolibrary.org/obo/obi.owl
domain: OBI:0000011 ! planned process
is_a: has_participant ! has participant

[Typedef]
id: OBI:0000312
name: is_specified_output_of
def: "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of." []
property_value: IAO:0000111 "is_specified_output_of" xsd:string
property_value: IAO:0000111 "is_specified_output_of" xsd:string
property_value: IAO:0000114 IAO:0000122
property_value: IAO:0000117 "Alan Ruttenberg" xsd:string
property_value: IAO:0000117 "PERSON:Bjoern Peters" xsd:string
property_value: IAO:0000412 http://purl.obolibrary.org/obo/obi.owl
range: OBI:0000011 ! planned process
is_a: participates_in ! participates in

[Typedef]
id: RO:0001018
name: obsolete contained in
property_value: editor_note "Containment is location not involving parthood, and arises only where some immaterial continuant is involved." xsd:string
property_value: editor_note "Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation.    If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows:    c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):" xsd:string
property_value: IAO:0000111 "contained in" xsd:string
property_value: IAO:0000118 "contained_in" xsd:string
property_value: seeAlso https://github.com/oborel/obo-relations/issues/693
is_obsolete: true

[Typedef]
id: RO:0002008
name: coincident with
def: "A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other." []
comment: Example: if we define region of chromosome as any subdivision of a chromosome along its long axis, then we can define a region of chromosome that contains only gene x as 'chromosome region' that coincident_with some 'gene x', where the term gene X corresponds to a genomic sequence.
subset: ro-eco
property_value: editor_note "Note from NCEAS meeting: consider changing primary label" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
is_a: mereotopologically_related_to ! mereotopologically related to

[Typedef]
id: RO:0015006
name: different in magnitude relative to
def: "q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [https://orcid.org/0000-0002-6601-2165]
domain: PATO:0000001 ! quality
range: PATO:0000001 ! quality

[Typedef]
id: RO:0015007
name: increased in magnitude relative to
def: "q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [https://orcid.org/0000-0002-6601-2165]
comment: This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'.
domain: PATO:0000001 ! quality
range: PATO:0000001 ! quality
is_a: RO:0015006 ! different in magnitude relative to

[Typedef]
id: RO:0015008
name: decreased in magnitude relative to
def: "q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [https://orcid.org/0000-0002-6601-2165]
comment: This relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'.
domain: PATO:0000001 ! quality
range: PATO:0000001 ! quality
is_a: RO:0015006 ! different in magnitude relative to

[Typedef]
id: acts_on_population_of
name: acts on population of
def: "p acts on population of c iff c' is a collection, has members of type c, and p has participant c" []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0012003
is_a: has_participant ! has participant
created_by: https://orcid.org/0000-0003-1813-6857
creation_date: 2020-06-08T17:21:33Z

[Typedef]
id: acts_upstream_of
name: acts upstream of
def: "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." []
subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
xref: RO:0002263
property_value: IAO:0000112 "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision." xsd:string
property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of
holds_over_chain: enables causally_upstream_of
is_a: acts_upstream_of_or_within ! acts upstream of or within

[Typedef]
id: acts_upstream_of,_negative_effect
name: acts upstream of, negative effect
def: "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" []
subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
xref: RO:0004035
property_value: RO:0004050 RO:0002263
property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of,_negative_effect
property_value: seeAlso "https://wiki.geneontology.org/Acts_upstream_of,_negative_effect" xsd:anyURI
holds_over_chain: enables causally_upstream_of,_negative_effect
is_a: acts_upstream_of ! acts upstream of
is_a: acts_upstream_of_or_within,_negative_effect ! acts upstream of or within, negative effect
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-01-26T23:53:22Z

[Typedef]
id: acts_upstream_of,_positive_effect
name: acts upstream of, positive effect
def: "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" []
subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
xref: RO:0004034
property_value: RO:0004049 RO:0002263
property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of,_positive_effect
property_value: seeAlso "https://wiki.geneontology.org/Acts_upstream_of,_positive_effect" xsd:anyURI
holds_over_chain: enables causally_upstream_of,_positive_effect
is_a: acts_upstream_of ! acts upstream of
is_a: acts_upstream_of_or_within,_positive_effect ! acts upstream of or within, positive effect
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-01-26T23:53:14Z

[Typedef]
id: acts_upstream_of_or_within
name: acts upstream of or within
def: "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." []
subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
synonym: "affects" RELATED []
xref: RO:0002264
property_value: IAO:0000112 "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway." xsd:string
property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within
property_value: seeAlso "https://wiki.geneontology.org/Acts_upstream_of_or_within" xsd:anyURI
holds_over_chain: enables causally_upstream_of_or_within
is_a: causal_agent_in_process ! causal agent in process

[Typedef]
id: acts_upstream_of_or_within,_negative_effect
name: acts upstream of or within, negative effect
subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
xref: RO:0004033
property_value: RO:0004050 RO:0002264
property_value: seeAlso "https://wiki.geneontology.org/Acts_upstream_of_or_within,_negative_effect" xsd:anyURI
holds_over_chain: enables causally_upstream_of_or_within,_negative_effect
is_a: acts_upstream_of_or_within ! acts upstream of or within
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-01-26T23:49:51Z

[Typedef]
id: acts_upstream_of_or_within,_positive_effect
name: acts upstream of or within, positive effect
subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
xref: RO:0004032
property_value: RO:0004049 RO:0002264
property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect
property_value: seeAlso "https://wiki.geneontology.org/Acts_upstream_of_or_within,_positive_effect" xsd:anyURI
holds_over_chain: enables causally_upstream_of_or_within,_positive_effect
is_a: acts_upstream_of_or_within ! acts upstream of or within
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-01-26T23:49:30Z

[Typedef]
id: adjacent_to
name: adjacent to
namespace: spatial
namespace: uberon
def: "x adjacent to y if and only if x and y share a boundary." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002220
property_value: editor_note "This relation acts as a join point with BSPO" xsd:string
property_value: IAO:0000112 "A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts." xsd:string {seeAlso="issuecomment-218584934"}
property_value: IAO:0000112 "The epidermis layer of a vertebrate is adjacent to the dermis." xsd:string
property_value: IAO:0000112 "The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies." xsd:string
property_value: IAO:0000112 "The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used." xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: RO:0001900 RO:0001901
domain: BFO:0000004 ! independent continuant
range: BFO:0000004 ! independent continuant
is_symmetric: true
is_a: spatially_disjoint_from ! spatially disjoint from

[Typedef]
id: anterior_to
name: anterior to
namespace: spatial
namespace: uberon
def: "x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail." [BSPO:cjm]
synonym: "rostral_to" EXACT []
xref: BSPO:0000096
property_value: seeAlso FBcv:0000039
property_value: seeAlso FBql:00005863
is_transitive: true
inverse_of: posterior_to ! posterior to

[Typedef]
id: anteriorly_connected_to
name: anteriorly connected to
namespace: uberon
def: "x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern]
is_a: connected_to ! connected to
is_a: posterior_to ! posterior to
is_a: transitively_anteriorly_connected_to ! transitively anteriorly connected to

[Typedef]
id: approximately_perpendicular_to
name: approximately perpendicular to
namespace: spatial
def: "Crosses at an angle that is 90 degrees, or close to 90 degrees. In any non-linear organism, the main axes are rarely perpendicular when taken through the organism as a whole." [BSPO:cjm]
xref: BSPO:0000104
domain: BSPO:0000010 ! anatomical axis
range: BSPO:0000010 ! anatomical axis

[Typedef]
id: attaches_to
name: attached to
namespace: uberon
def: "a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a" []
subset: ro-eco
xref: RO:0002371
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000589 "attached to (anatomical structure to anatomical structure)" xsd:string
is_symmetric: true
is_a: attaches_to_part_of ! attached to part of
is_a: connected_to ! connected to

[Typedef]
id: attaches_to_part_of
name: attached to part of
namespace: uberon
def: "a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b." []
xref: RO:0002177
property_value: IAO:0000589 "attached to part of (anatomical structure to anatomical structure)" xsd:string
domain: UBERON:0000061 ! anatomical structure
range: UBERON:0000061 ! anatomical structure
holds_over_chain: attaches_to part_of {RO:0002582="true"}
is_a: biomechanically_related_to ! biomechanically related to
is_a: mereotopologically_related_to ! mereotopologically related to

[Typedef]
id: before_or_simultaneous_with
name: before or simultaneous with
comment: Primitive instance level timing relation between events
subset: ro-eco
xref: RO:0002081
property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string
property_value: IAO:0000118 "<=" xsd:string
is_a: temporally_related_to ! temporally related to

[Typedef]
id: biomechanically_related_to
name: biomechanically related to
def: "A relation that holds between elements of a musculoskeletal system or its analogs." []
xref: RO:0002567
property_value: curator_notes "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
domain: UBERON:0000061 ! anatomical structure
range: UBERON:0000061 ! anatomical structure
is_a: functionally_related_to ! functionally related to

[Typedef]
id: bounding_layer_of
name: bounding layer of
namespace: uberon
def: "X outer_layer_of Y iff:\n. X :continuant that bearer_of some PATO:laminar\n. X part_of Y\n. exists Z :surface\n. X has_boundary Z\n. Z boundary_of Y\n\nhas_boundary: http://purl.obolibrary.org/obo/RO_0002002\nboundary_of: http://purl.obolibrary.org/obo/RO_0002000" []
comment: A relationship that applies between a continuant and its outer, bounding layer.  Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane.
subset: ro-eco
xref: RO:0002007
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
range: BFO:0000040 ! material entity
is_a: part_of ! part_of

[Typedef]
id: branching_part_of
name: branching part of
namespace: uberon
def: "x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y" []
subset: ro-eco
xref: RO:0002380
property_value: IAO:0000112 "In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is a (direct) branching part of T. B1-1, B1-2, and B1-3 are also branching parts of T, but these are considered indirect branching parts as they do not directly connect to the main stem S" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: seeAlso "FMA:85994" xsd:string
property_value: seeAlso https://github.com/obophenotype/uberon/issues/2212
is_a: in_branching_relationship_with ! in branching relationship with
is_a: part_of ! part_of
inverse_of: has_branching_part ! has branching part

[Typedef]
id: capable_of
name: capable of
namespace: uberon
def: "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " []
subset: ro-eco
xref: RO:0002215
property_value: curator_notes "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"." xsd:string
property_value: IAO:0000112 "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)" xsd:string
property_value: IAO:0000112 "osteoclast SubClassOf 'capable of' some 'bone resorption'" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "has function realized in" xsd:string
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20123131
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/21208450
domain: BFO:0000004 ! independent continuant
range: BFO:0000015 ! process
is_a: capable_of_part_of ! capable of part of

[Typedef]
id: capable_of_negatively_regulating
name: capable of negatively regulating
def: "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." []
xref: RO:0002597
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
holds_over_chain: capable_of negatively_regulates
is_a: capable_of_regulating ! capable of regulating

[Typedef]
id: capable_of_part_of
name: capable of part of
namespace: uberon
def: "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." []
xref: RO:0002216
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "has function in" xsd:string
property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/reflexivity/
holds_over_chain: capable_of part_of {RO:0002582="true"}
is_a: causal_agent_in_process ! causal agent in process
is_a: functionally_related_to ! functionally related to

[Typedef]
id: capable_of_positively_regulating
name: capable of positively regulating
def: "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." []
xref: RO:0002598
property_value: IAO:0000112 "renin -> arteriolar smooth muscle contraction" xsd:string
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
holds_over_chain: capable_of positively_regulates
is_a: capable_of_regulating ! capable of regulating

[Typedef]
id: capable_of_regulating
name: capable of regulating
def: "Holds between c and p if and only if c is capable of some activity a, and a regulates p." []
xref: RO:0002596
property_value: IAO:0000112 "pyrethroid -> growth" xsd:string
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
holds_over_chain: capable_of regulates
is_a: causal_agent_in_process ! causal agent in process

[Typedef]
id: causal_agent_in_process
name: causal agent in process
def: "A relationship between a material entity and a process where the material entity has some causal role that influences the process" []
xref: RO:0002500
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
is_a: causal_relation_between_material_entity_and_a_process ! causal relation between material entity and a process
inverse_of: process_has_causal_agent ! process has causal agent

[Typedef]
id: causal_relation_between_entities
name: causal relation between entities
xref: RO:0002506
property_value: curator_notes "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string
property_value: editor_note "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
domain: BFO:0000002 ! continuant
range: BFO:0000002 ! continuant
is_a: causally_related_to ! causally related to

[Typedef]
id: causal_relation_between_material_entity_and_a_process
name: causal relation between material entity and a process
def: "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." []
xref: RO:0002595
property_value: editor_note "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
domain: BFO:0000040 ! material entity
range: BFO:0000015 ! process
is_a: causally_related_to ! causally related to

[Typedef]
id: causal_relation_between_processes
name: causal relation between processes
def: "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." []
xref: RO:0002501
property_value: curator_notes "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
domain: BFO:0000003 ! occurrent
range: BFO:0000003 ! occurrent
is_a: causally_related_to ! causally related to

[Typedef]
id: causally_downstream_of
name: causally downstream of
def: "inverse of upstream of" []
xref: RO:0002404
property_value: IAO:0000114 IAO:0000428
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: causally_downstream_of_or_within ! causally downstream of or within
is_a: preceded_by ! preceded by
inverse_of: causally_upstream_of ! causally upstream of

[Typedef]
id: causally_downstream_of_or_within
name: causally downstream of or within
def: "inverse of causally upstream of or within" []
subset: RO:0002259
xref: RO:0002427
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
is_transitive: true
is_a: causal_relation_between_processes ! causal relation between processes

[Typedef]
id: causally_influenced_by
name: causally influenced by
xref: RO:0002559
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
property_value: IAO:0000589 "causally influenced by (entity-centric)" xsd:string
is_a: causal_relation_between_entities ! causal relation between entities
inverse_of: causally_influences ! causally influences

[Typedef]
id: causally_influences
name: causally influences
def: "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." []
xref: RO:0002566
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
property_value: IAO:0000589 "causally influences (entity-centric)" xsd:string
domain: BFO:0000002 ! continuant
range: BFO:0000002 ! continuant
is_a: causal_relation_between_entities ! causal relation between entities

[Typedef]
id: causally_related_to
name: causally related to
def: "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." [https://en.wikipedia.org/wiki/Causality]
xref: RO:0002410
property_value: curator_notes "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string
property_value: editor_note "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative?\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165

[Typedef]
id: causally_upstream_of
name: causally upstream of
def: "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002411
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_transitive: true
is_a: causally_upstream_of_or_within ! causally upstream of or within
is_a: precedes ! precedes

[Typedef]
id: causally_upstream_of,_negative_effect
name: causally upstream of, negative effect
def: "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002305
property_value: http://purl.org/dc/terms/creator https://orcid.org/0000-0002-6601-2165
property_value: RO:0004050 RO:0002411
property_value: seeAlso https://wiki.geneontology.org/Causally_upstream_of,_negative_effect
is_a: causally_upstream_of ! causally upstream of
is_a: causally_upstream_of_or_within,_negative_effect ! causally upstream of or within, negative effect

[Typedef]
id: causally_upstream_of,_positive_effect
name: causally upstream of, positive effect
def: "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." []
comment: holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002304
property_value: http://purl.org/dc/terms/creator https://orcid.org/0000-0002-6601-2165
property_value: RO:0004049 RO:0002411
property_value: seeAlso https://wiki.geneontology.org/Causally_upstream_of,_positive_effect
is_a: causally_upstream_of ! causally upstream of
is_a: causally_upstream_of_or_within,_positive_effect ! causally upstream of or within, positive effect

[Typedef]
id: causally_upstream_of_or_within
name: causally upstream of or within
def: "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." []
synonym: "affects" RELATED []
xref: RO:0002418
property_value: editor_note "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "influences (processual)" xsd:string
is_transitive: true
is_a: causal_relation_between_processes ! causal relation between processes
inverse_of: causally_downstream_of_or_within ! causally downstream of or within

[Typedef]
id: causally_upstream_of_or_within,_negative_effect
name: causally upstream of or within, negative effect
xref: RO:0004046
property_value: RO:0004050 RO:0002418
property_value: seeAlso "https://wiki.geneontology.org/Causally_upstream_of_or_within,_negative_effect" xsd:anyURI
is_a: causally_upstream_of_or_within ! causally upstream of or within
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-03-13T23:55:05Z

[Typedef]
id: causally_upstream_of_or_within,_positive_effect
name: causally upstream of or within, positive effect
xref: RO:0004047
property_value: RO:0004049 RO:0002418
property_value: seeAlso https://wiki.geneontology.org/Causally_upstream_of_or_within,_positive_effect
is_a: causally_upstream_of_or_within ! causally upstream of or within
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-03-13T23:55:19Z

[Typedef]
id: channel_for
name: channel for
namespace: uberon
synonym: "carries" BROAD []
domain: UBERON:0004111 ! anatomical conduit
range: UBERON:0000463 ! organism substance

[Typedef]
id: channels_from
name: channels_from
namespace: uberon
is_transitive: true

[Typedef]
id: channels_into
name: channels_into
namespace: uberon
is_transitive: true

[Typedef]
id: characteristic_of
name: characteristic of
def: "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence." []
comment: Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.
xref: RO:0000052
property_value: IAO:0000111 "inheres in" xsd:string
property_value: IAO:0000112 "this fragility is a characteristic of this vase" xsd:string
property_value: IAO:0000112 "this red color is a characteristic of this apple" xsd:string
property_value: IAO:0000118 "inheres_in" xsd:string
property_value: RO:0001900 RO:0001901
is_functional: true
is_a: characteristic_of_part_of ! characteristic of part of
inverse_of: has_characteristic ! has characteristic

[Typedef]
id: characteristic_of_part_of
name: characteristic of part of
def: "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." []
xref: RO:0002314
property_value: editor_note "Because part_of is transitive, inheres in is a sub-relation of characteristic of part of" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "inheres in part of" xsd:string
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20064205
property_value: RO:0001900 RO:0001901
property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/reflexivity/
holds_over_chain: characteristic_of part_of {RO:0002582="true"}
is_a: depends_on ! depends on
transitive_over: part_of ! part_of

[Typedef]
id: composed_primarily_of
name: composed primarily of
namespace: uberon
def: "x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y." []
subset: ro-eco
xref: RO:0002473
property_value: IAO:0000112 "'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552
property_value: RO:0001900 RO:0001901
domain: BFO:0000040 ! material entity
range: BFO:0000040 ! material entity
is_a: has_part ! has part

[Typedef]
id: conduit_for
name: conduit for
namespace: uberon
def: "x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x." []
subset: ro-eco
xref: RO:0002570
property_value: curator_notes "This relation holds between a thing with a 'conduit' (e.g. a bone foramen) and a 'conduee' (for example, a nerve) such that at the time the relationship holds, the conduee has two ends sticking out either end of the conduit. It should therefore note be used for objects that move through the conduit but whose spatial extent does not span the passage. For example, it would not be used for a mountain that contains a long tunnel through which trains pass. Nor would we use it for a digestive tract and objects such as food that pass through." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "UBERON:cjm" xsd:string
domain: BFO:0000040 ! material entity
range: BFO:0000040 ! material entity
is_a: overlaps ! overlaps

[Typedef]
id: connected_to
name: connected to
namespace: uberon
def: "a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b" []
xref: RO:0002170
property_value: IAO:0000112 "a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones)." xsd:string
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern" xsd:anyURI
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern" xsd:anyURI
is_a: mereotopologically_related_to ! mereotopologically related to

[Typedef]
id: connecting_branch_of
name: connecting branch of
namespace: uberon
def: "b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t." []
xref: RO:0002252
property_value: IAO:0000112 "In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is connecting branch of S, and B1-1 as a connecting branch of B1." xsd:string
property_value: RO:0004036 BFO:0000050
property_value: seeAlso https://github.com/obophenotype/uberon/issues/2212
is_a: connected_to ! connected to
is_a: in_branching_relationship_with ! in branching relationship with
inverse_of: has_connecting_branch ! has connecting branch

[Typedef]
id: connects
name: connects
namespace: uberon
def: "c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system." []
xref: RO:0002176
property_value: IAO:0000112 "a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones)." xsd:string
property_value: IAO:0000112 "The M8 connects Glasgow and Edinburgh" xsd:string
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern" xsd:anyURI
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern" xsd:anyURI
domain: BFO:0000004 ! independent continuant
is_a: mereotopologically_related_to ! mereotopologically related to

[Typedef]
id: contains_process
name: contains process
namespace: uberon
def: "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t" []
comment: Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant
xref: BFO:0000067
property_value: IAO:0000111 "site of" xsd:string
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl

[Typedef]
id: continuous_with
name: continuous with
namespace: uberon
def: "X continuous_with Y if and only if X and Y share a fiat boundary." []
xref: RO:0002150
property_value: curator_notes "The label for this relation was previously connected to. I relabeled this to \"continuous with\". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint)" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: IAO:0000118 "connected to" xsd:string
property_value: RO:0001900 RO:0001901
property_value: seeAlso "FMA:85972" xsd:string
domain: BFO:0000004 ! independent continuant
range: BFO:0000004 ! independent continuant
is_symmetric: true
is_a: mereotopologically_related_to ! mereotopologically related to

[Typedef]
id: contralateral_to
name: contralateral to
namespace: spatial
def: "On the opposite side from. For example, the left arm is contralateral to the right arm (and the right leg)." [BSPO:cjm]
xref: BSPO:0000106
property_value: seeAlso FBql:00005851
is_symmetric: true
is_a: opposite_to ! opposite to

[Typedef]
id: contributes_to_morphology_of
name: contributes to morphology of
namespace: uberon
def: "p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm." []
xref: RO:0002433
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: overlaps ! overlaps

[Typedef]
id: curator_notes
name: curator note
name: curator notes
namespace: uberon
def: "An administrative note of use for a curator but of no use for a user" []
xref: IAO:0000232
property_value: IAO:0000111 "curator note" xsd:string
property_value: IAO:0000114 IAO:0000122
property_value: IAO:0000117 "PERSON:Alan Ruttenberg" xsd:string
property_value: isDefinedBy http://purl.obolibrary.org/obo/iao.owl
is_metadata_tag: true

[Typedef]
id: dc-creator
name: creator
namespace: uberon
xref: http://purl.org/dc/elements/1.1/creator
is_metadata_tag: true

[Typedef]
id: dc-description
name: description
namespace: uberon
xref: http://purl.org/dc/elements/1.1/description
is_metadata_tag: true

[Typedef]
id: dc-title
name: title
namespace: uberon
xref: http://purl.org/dc/elements/1.1/title
is_metadata_tag: true

[Typedef]
id: dcterms-isReferencedBy
name: is referenced by
name: isReferencedBy
namespace: uberon
def: "A related resource that references, cites, or otherwise points to the described resource." []
xref: http://purl.org/dc/terms/isReferencedBy
is_metadata_tag: true

[Typedef]
id: dcterms-license
name: license
namespace: uberon
xref: http://purl.org/dc/terms/license
is_metadata_tag: true

[Typedef]
id: decreased_in_magnitude_relative_to
name: obsolete decreased_in_magnitude_relative_to
namespace: quality
def: "OBSOLETE. q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [PATOC:CJM]
comment: Refer to https://github.com/pato-ontology/pato/issues/454 for obsoletion reason. This relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'.
domain: PATO:0000001 ! quality
range: PATO:0000001 ! quality
is_transitive: true
is_obsolete: true
replaced_by: RO:0015008

[Typedef]
id: deep_to
name: deep to
namespace: spatial
namespace: uberon
def: "Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines." [BSPO:cjm]
xref: BSPO:0000107
is_transitive: true
inverse_of: superficial_to ! superficial to

[Typedef]
id: depends_on
name: depends on
xref: RO:0002502
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: seeAlso BFO:0000169

[Typedef]
id: depiction
name: depiction
namespace: uberon
xref: http://xmlns.com/foaf/0.1/depiction
is_metadata_tag: true

[Typedef]
id: developmentally_contributes_to
name: developmentally contributes to
def: "inverse of has developmental contribution from" []
subset: RO:0002259
xref: RO:0002255
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
holds_over_chain: develops_into part_of
is_a: developmentally_succeeded_by ! developmentally succeeded by
is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to

[Typedef]
id: developmentally_induced_by
name: developmentally induced by
namespace: uberon
def: "t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T" []
xref: RO:0002256
property_value: curator_notes "We place this under 'developmentally preceded by'. This placement should be examined in the context of reciprocal inductions[cjm]" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: IAO:0000118 "induced by" xsd:string
property_value: IAO:0000119 " Developmental Biology, Gilbert, 8th edition, figure 6.5(F)" xsd:string
property_value: IAO:0000119 "GO:0001759" xsd:string
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20064205
domain: UBERON:0000465 ! material anatomical entity
range: UBERON:0000465 ! material anatomical entity
is_a: developmentally_preceded_by ! developmentally preceded by
inverse_of: developmentally_induces ! developmentally induces

[Typedef]
id: developmentally_induces
name: developmentally induces
def: "Inverse of developmentally induced by" []
xref: RO:0002257
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: developmentally_succeeded_by ! developmentally succeeded by
is_a: has_potential_to_developmentally_induce ! has potential to developmentally induce

[Typedef]
id: developmentally_preceded_by
name: developmentally preceded by
def: "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p" []
comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from
xref: RO:0002258
property_value: curator_notes "In general you should not use this relation to make assertions - use one of the more specific relations below this one" xsd:string
property_value: editor_note "false" xsd:boolean
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
domain: BFO:0000002 ! continuant
range: BFO:0000002 ! continuant
is_a: developmentally_related_to ! developmentally related to
inverse_of: developmentally_succeeded_by ! developmentally succeeded by

[Typedef]
id: developmentally_related_to
name: developmentally related to
def: "A relationship that holds between entities participating in some developmental process (GO:0032502)" []
xref: RO:0002324
property_value: curator_notes "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165

[Typedef]
id: developmentally_replaces
name: developmentally replaces
namespace: uberon
def: "x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else" []
xref: RO:0002285
property_value: editor_note "This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "replaces" xsd:string
is_a: developmentally_preceded_by ! developmentally preceded by

[Typedef]
id: developmentally_succeeded_by
name: developmentally succeeded by
def: "Inverse of developmentally preceded by" []
xref: RO:0002286
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: has_developmental_potential_involving ! has developmental potential involving

[Typedef]
id: develops_from
name: develops from
namespace: uberon
def: "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y" []
comment: This is the transitive form of the develops from relation
xref: RO:0002202
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228
domain: BFO:0000004 ! independent continuant
range: BFO:0000004 ! independent continuant
is_transitive: true
is_a: developmentally_preceded_by ! developmentally preceded by
is_a: has_developmental_contribution_from ! has developmental contribution from
inverse_of: develops_into ! develops into

[Typedef]
id: develops_from_part_of
name: develops from part of
namespace: uberon
def: "x develops from part of y if and only if there exists some z such that x develops from z and z is part of y" []
xref: RO:0002225
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
holds_over_chain: directly_develops_from part_of
is_a: develops_from ! develops from

[Typedef]
id: develops_in
name: develops in
namespace: uberon
def: "x develops_in y if x is located in y whilst x is developing" []
xref: RO:0002226
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "EHDAA2" xsd:string
property_value: IAO:0000119 "Jonathan Bard, EHDAA2" xsd:string
domain: UBERON:0001062 ! anatomical entity
holds_over_chain: directly_develops_from located_in
is_a: developmentally_preceded_by ! developmentally preceded by

[Typedef]
id: develops_into
name: develops into
namespace: uberon
def: "inverse of develops from" []
subset: RO:0002259
xref: RO:0002203
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228
is_transitive: true
is_a: developmentally_succeeded_by ! developmentally succeeded by
is_a: has_potential_to_develop_into ! has potential to develop into
is_a: has_potential_to_directly_develop_into ! has potential to directly develop into

[Typedef]
id: device_utilizes_material
name: device utilizes material
def: "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." []
synonym: "utilizes" BROAD []
xref: RO:0017001
property_value: curator_notes "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input." xsd:string
property_value: curator_notes "See github ticket https://github.com/oborel/obo-relations/issues/497" xsd:string
property_value: IAO:0000112 "A diagnostic testing device utilizes a specimen." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0001-9625-1899
property_value: IAO:0000117 https://orcid.org/0000-0003-2620-0345
holds_over_chain: capable_of has_input
creation_date: 2021-11-08T12:00:00Z

[Typedef]
id: different_in_magnitude_relative_to
name: obsolete different_in_magnitude_relative_to
namespace: quality
def: "OBSOLETE. q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [PATOC:CJM]
comment: Refer to https://github.com/pato-ontology/pato/issues/454 for obsoletion reason.
domain: PATO:0000001 ! quality
range: PATO:0000001 ! quality
is_obsolete: true
replaced_by: RO:0015006

[Typedef]
id: directly_develops_from
name: directly develops from
namespace: uberon
def: "Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y." []
comment: TODO - add child relations from DOS
synonym: "has developmental precursor" EXACT []
xref: RO:0002207
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: IAO:0000119 "FBbt" xsd:string
property_value: RO:0002575 RO:0002202
is_a: develops_from ! develops from
inverse_of: directly_develops_into ! directly develops into

[Typedef]
id: directly_develops_into
name: directly develops into
def: "inverse of directly develops from" []
subset: RO:0002259
xref: RO:0002210
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000118 "developmental precursor of" xsd:string
is_a: develops_into ! develops into

[Typedef]
id: directly_negatively_regulated_by
name: directly negatively regulated by
def: "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." [GOC:dos]
def: "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." [https://orcid.org/0000-0002-7073-9172]
xref: RO:0002023
is_a: directly_regulated_by ! directly regulated by
inverse_of: directly_negatively_regulates ! directly negatively regulates
created_by: dos
created_by: https://orcid.org/0000-0002-7073-9172
creation_date: 2017-09-17T13:52:38Z

[Typedef]
id: directly_negatively_regulates
name: directly negatively regulates
def: "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002630
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
property_value: IAO:0000589 "directly negatively regulates (process to process)" xsd:string
property_value: RO:0004050 RO:0002578
property_value: seeAlso "https://wiki.geneontology.org/Directly_negatively_regulates" xsd:anyURI
is_a: directly_regulates ! directly regulates
is_a: negatively_regulates ! negatively regulates

[Typedef]
id: directly_negatively_regulates_activity_of
name: directly negatively regulates activity of
def: "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B." []
synonym: "molecularly decreases activity of" EXACT []
xref: RO:0002449
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431
property_value: IAO:0000118 "directly inhibits" xsd:string
domain: BFO:0000040 ! material entity
range: BFO:0000040 ! material entity
is_a: directly_regulates_activity_of ! directly regulates activity of

[Typedef]
id: directly_positively_regulated_by
name: directly positively regulated by
def: "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." [GOC:dos]
def: "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." [https://orcid.org/0000-0002-7073-9172]
xref: RO:0002024
is_a: directly_regulated_by ! directly regulated by
inverse_of: directly_positively_regulates ! directly positively regulates
created_by: dos
created_by: https://orcid.org/0000-0002-7073-9172
creation_date: 2017-09-17T13:52:47Z

[Typedef]
id: directly_positively_regulates
name: directly positively regulates
def: "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002629
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
property_value: IAO:0000589 "directly positively regulates (process to process)" xsd:string
property_value: RO:0004049 RO:0002578
property_value: seeAlso "https://wiki.geneontology.org/Directly_positively_regulates" xsd:anyURI
is_a: directly_regulates ! directly regulates
is_a: positively_regulates ! positively regulates

[Typedef]
id: directly_positively_regulates_activity_of
name: directly positively regulates activity of
def: "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B." []
synonym: "molecularly increases activity of" EXACT []
xref: RO:0002450
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431
property_value: IAO:0000118 "directly activates" xsd:string
domain: BFO:0000040 ! material entity
range: BFO:0000040 ! material entity
is_a: directly_regulates_activity_of ! directly regulates activity of

[Typedef]
id: directly_regulated_by
name: directly regulated by
comment: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  regulates the kinase activity (P2) of protein B then P1 directly regulates P2. {xref="GOC:dos"}
comment: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  regulates the kinase activity (P2) of protein B then P1 directly regulates P2. {xref="https://orcid.org/0000-0002-7073-9172"}
xref: RO:0002022
is_a: regulated_by ! regulated by
inverse_of: directly_regulates ! directly regulates
created_by: dos
created_by: https://orcid.org/0000-0002-7073-9172
creation_date: 2017-09-17T13:52:24Z

[Typedef]
id: directly_regulates
name: directly regulates
def: "p directly regulates q iff p is immediately causally upstream of q and p regulates q." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002578
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
property_value: IAO:0000589 "directly regulates (processual)" xsd:string
property_value: RO:0002575 RO:0002211
is_a: immediately_causally_upstream_of ! immediately causally upstream of
is_a: regulates ! regulates

[Typedef]
id: directly_regulates_activity_of
name: directly regulates activity of
def: "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B." []
synonym: "molecularly controls" EXACT []
xref: RO:0002448
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431
domain: BFO:0000040 ! material entity
range: BFO:0000040 ! material entity
is_a: molecularly_interacts_with ! molecularly interacts with
is_a: regulates_activity_of ! regulates activity of

[Typedef]
id: disposition_of
name: disposition of
def: "inverse of has disposition" []
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.
subset: RO:0002259
xref: RO:0000092
is_a: characteristic_of ! characteristic of

[Typedef]
id: distal_to
name: distal to
namespace: spatial
namespace: uberon
def: "x distal to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal)." [BSPO:cjm]
xref: BSPO:0000097
property_value: seeAlso FBcv:0000040
property_value: seeAlso FBql:00005867
is_transitive: true
inverse_of: proximal_to ! proximal to

[Typedef]
id: distally_connected_to
name: distally connected to
namespace: uberon
def: "x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern]
is_a: connected_to ! connected to
is_a: proximal_to ! proximal to
is_a: transitively_distally_connected_to ! transitively distally connected to
inverse_of: proximally_connected_to ! proximally connected to

[Typedef]
id: distalmost_part_of
name: distalmost part of
namespace: spatial
namespace: uberon
def: "X distalmost part of Y <=> X is in distal side of Y and X is adjacent to the distal boundary of Y" [https://orcid.org/0000-0002-6601-2165]
xref: BSPO:0001108
is_a: in_distal_side_of ! in distal side of

[Typedef]
id: dorsal_to
name: dorsal to
namespace: spatial
namespace: uberon
def: "x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly)." [BSPO:cjm]
xref: BSPO:0000098
property_value: seeAlso FBcv:0000041
property_value: seeAlso FBql:00005865
is_transitive: true
inverse_of: ventral_to ! ventral to

[Typedef]
id: drains
name: drains
namespace: uberon
def: "Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure." []
xref: RO:0002179
property_value: editor_note "Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between a vein and an anatomical structure" xsd:string
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20064205
domain: UBERON:0001638 ! vein
is_a: connected_to ! connected to

[Typedef]
id: editor_note
name: editor note
namespace: uberon
def: "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology." []
xref: IAO:0000116
property_value: IAO:0000111 "editor note" xsd:string
property_value: IAO:0000114 IAO:0000122
property_value: IAO:0000117 "PERSON:Daniel Schober" xsd:string
property_value: IAO:0000119 "GROUP:OBI:<http://purl.obofoundry.org/obo/obi>" xsd:string
property_value: isDefinedBy http://purl.obolibrary.org/obo/iao.owl
is_metadata_tag: true

[Typedef]
id: enabled_by
name: enabled by
def: "inverse of enables" []
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002333
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: seeAlso "https://wiki.geneontology.org/Enabled_by" xsd:anyURI
is_a: functionally_related_to ! functionally related to
is_a: has_participant ! has participant

[Typedef]
id: enables
name: enables
def: "c enables p iff c is capable of p and c acts to execute p." []
subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
xref: RO:0002327
property_value: curator_notes "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized." xsd:string
property_value: IAO:0000112 "a particular instances of akt-2 enables some instance of protein kinase activity" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "catalyzes" xsd:string
property_value: IAO:0000118 "executes" xsd:string
property_value: IAO:0000118 "has" xsd:string
property_value: IAO:0000118 "is catalyzing" xsd:string
property_value: IAO:0000118 "is executing" xsd:string
property_value: seeAlso "https://wiki.geneontology.org/Enables" xsd:anyURI
is_a: capable_of ! capable of
inverse_of: enabled_by ! enabled by
transitive_over: has_component_activity ! has component activity
transitive_over: has_part ! has part

[Typedef]
id: enables_subfunction
name: enables subfunction
def: "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." []
xref: RO:0004031
holds_over_chain: enables has_part
is_a: functionally_related_to ! functionally related to
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-01-25T23:20:13Z

[Typedef]
id: ends
name: ends
namespace: uberon
def: "inverse of ends with" []
subset: ro-eco
xref: RO:0002229
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 "Chris Mungall" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: part_of ! part_of
is_a: temporally_related_to ! temporally related to
inverse_of: ends_with ! ends with

[Typedef]
id: ends_after
name: ends after
comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)
subset: ro-eco
xref: RO:0002086
property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string
is_transitive: true
is_a: temporally_related_to ! temporally related to

[Typedef]
id: ends_with
name: ends with
namespace: uberon
def: "x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." []
subset: ro-eco
xref: RO:0002230
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 "Chris Mungall" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "finished by" xsd:string
is_transitive: true
is_a: has_part ! has part
is_a: temporally_related_to ! temporally related to

[Typedef]
id: evolutionarily_related_to
name: evolutionarily related to
def: "A relationship that holds via some environmental process" []
xref: RO:0002320
property_value: curator_notes "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165

[Typedef]
id: existence_ends_during
name: existence ends during
namespace: uberon
def: "Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely." [https://orcid.org/0000-0002-6601-2165]
def: "x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y)." []
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.
synonym: "ceases_to_exist_during" EXACT []
xref: RO:0002492
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: existence_ends_during_or_before ! existence ends during or before
is_a: existence_overlaps ! existence overlaps
transitive_over: part_of ! part_of

[Typedef]
id: existence_ends_during_or_before
name: existence ends during or before
namespace: uberon
def: "x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends." []
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.
xref: RO:0002497
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
holds_over_chain: developmentally_succeeded_by existence_ends_during_or_before
holds_over_chain: part_of existence_ends_during_or_before
is_a: relation_between_physical_entity_and_a_process_or_stage ! relation between physical entity and a process or stage
transitive_over: part_of ! part_of
transitive_over: precedes ! precedes
transitive_over: simultaneous_with ! simultaneous with

[Typedef]
id: existence_ends_with
name: existence ends with
namespace: uberon
def: "x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y)." []
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.
xref: RO:0002493
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: existence_ends_during ! existence ends during

[Typedef]
id: existence_overlaps
name: existence overlaps
def: "x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))" []
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.
xref: RO:0002490
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: relation_between_physical_entity_and_a_process_or_stage ! relation between physical entity and a process or stage

[Typedef]
id: existence_starts_and_ends_during
name: existence starts and ends during
namespace: uberon
def: "x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y)" []
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.
synonym: "exists during" EXACT []
xref: RO:0002491
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: existence_ends_during ! existence ends during
is_a: existence_starts_during ! existence starts during

[Typedef]
id: existence_starts_during
name: existence starts during
namespace: uberon
def: "x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y)." []
xref: RO:0002488
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: existence_overlaps ! existence overlaps
is_a: existence_starts_during_or_after ! existence starts during or after
transitive_over: part_of ! part_of

[Typedef]
id: existence_starts_during_or_after
name: existence starts during or after
namespace: uberon
def: "x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y)." []
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.
xref: RO:0002496
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
holds_over_chain: developmentally_preceded_by existence_starts_during_or_after
holds_over_chain: part_of existence_starts_during_or_after
is_a: relation_between_physical_entity_and_a_process_or_stage ! relation between physical entity and a process or stage
transitive_over: part_of ! part_of
transitive_over: preceded_by ! preceded by
transitive_over: simultaneous_with ! simultaneous with

[Typedef]
id: existence_starts_with
name: existence starts with
namespace: uberon
def: "x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y)." []
xref: RO:0002489
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: existence_starts_during ! existence starts during

[Typedef]
id: extends_fibers_into
name: extends_fibers_into
namespace: uberon
def: "X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y" [https://orcid.org/0000-0002-7073-9172]
is_symmetric: true
is_a: connected_to ! connected to

[Typedef]
id: filtered_through
name: filtered through
namespace: uberon
def: "Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity." []
comment: Relationship between a fluid and a filtration barrier, where the portion of fluid arises as a transformation of another portion of fluid on the other side of the barrier, with larger particles removed

[Typedef]
id: finishes_axis
name: finishes axis
namespace: spatial
comment: A directional axis can be divided by a plane. Following Allen Interval Algebra terminology we say that the side on which the axis initiates starts the axis, with the other side finishing the axis. If s finishes axis x, and x has end point p, then x overlaps p
xref: BSPO:0015001
domain: BSPO:0000054 ! anatomical side
range: BSPO:0000010 ! anatomical axis

[Typedef]
id: formed_as_result_of
name: formed as result of
xref: RO:0002354
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: output_of ! output of

[Typedef]
id: function_of
name: function of
def: "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence" []
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.
xref: RO:0000079
property_value: editor_note "A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists." xsd:string
property_value: IAO:0000112 "this catalysis function is a function of this enzyme" xsd:string
property_value: IAO:0000118 "function_of" xsd:string
property_value: IAO:0000118 "is function of" xsd:string
domain: BFO:0000034 ! function
is_a: characteristic_of ! characteristic of
inverse_of: has_function ! has function

[Typedef]
id: functionally_related_to
name: functionally related to
namespace: uberon
def: "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." []
xref: RO:0002328
property_value: curator_notes "This is a grouping relation that collects relations used for the purpose of connecting structure and function" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165

[Typedef]
id: has_boundary
name: has 2D boundary
namespace: uberon
def: "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity" []
xref: RO:0002002
property_value: editor_note "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts." xsd:string
property_value: editor_note "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape." xsd:string
property_value: IAO:0000112 "my body has 2D boundary the surface of my skin" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: IAO:0000118 "has boundary" xsd:string
property_value: IAO:0000118 "has_2D_boundary" xsd:string
property_value: RO:0001900 RO:0001901
domain: BFO:0000040 ! material entity
range: BFO:0000141 ! immaterial entity
is_a: mereotopologically_related_to ! mereotopologically related to

[Typedef]
id: has_branching_part
name: has branching part
namespace: uberon
def: "inverse of branching part of" []
subset: ro-eco
subset: RO:0002259
xref: RO:0002569
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_transitive: true
is_a: has_part ! has part
is_a: in_branching_relationship_with ! in branching relationship with

[Typedef]
id: has_characteristic
name: has characteristic
def: "Inverse of characteristic_of" []
xref: RO:0000053
property_value: editor_note "A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist." xsd:string
property_value: IAO:0000111 "bearer of" xsd:string
property_value: IAO:0000112 "this apple is bearer of this red color" xsd:string
property_value: IAO:0000112 "this vase is bearer of this fragility" xsd:string
property_value: IAO:0000118 "bearer_of" xsd:string
property_value: IAO:0000118 "is bearer of" xsd:string
property_value: RO:0001900 RO:0001901
property_value: seeAlso "https://github.com/oborel/obo-relations/pull/284" xsd:string
range: BFO:0000020 ! characteristic
is_inverse_functional: true

[Typedef]
id: has_component
name: has component
name: has_component
namespace: protein
namespace: uberon
def: "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." []
subset: ro-eco
xref: RO:0002180
property_value: curator_notes "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit." xsd:string
property_value: editor_note "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity." xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: RO:0001900 RO:0001901
property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:Componency
is_transitive: false
is_a: has_part ! has part

[Typedef]
id: has_component_activity
name: has component activity
comment: A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B.
xref: RO:0002017
is_a: has_component_process ! has component process
created_by: dos
created_by: https://orcid.org/0000-0002-7073-9172
creation_date: 2017-05-24T09:44:33Z

[Typedef]
id: has_component_process
name: has component process
def: "w 'has process component' p if p and w are processes,  w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." []
xref: RO:0002018
domain: BFO:0000015 ! process
range: BFO:0000015 ! process
is_a: has_component ! has component
created_by: dos
created_by: https://orcid.org/0000-0002-7073-9172
creation_date: 2017-05-24T09:49:21Z

[Typedef]
id: has_connecting_branch
name: has connecting branch
def: "inverse of connecting branch of" []
subset: RO:0002259
xref: RO:0002253
property_value: RO:0004036 BFO:0000051
is_a: in_branching_relationship_with ! in branching relationship with

[Typedef]
id: has_constituent_monomer
name: has_constituent_monomer
namespace: protein
def: "A relation that holds between a polymer and its constituent monomers. P has_constituent_monomer c if and only if P has_component multiple instances of c and each instance of c is covalently attached to another instance of c." [PRO:DAN]
comment: The constituent monomers need not be covalently attached in an end-to-end manner; that is, polymers with internal connections (e.g., polyubiquitin) can use this relation, as can circular polymers (e.g., plasmids) and multi-branched polymers (e.g., glycans). This relation, as non-transitive, allows one to indicate the number of instances of c.
is_transitive: false
is_a: has_component ! has component

[Typedef]
id: has_cross_section
name: has cross section
def: "s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2." [https://orcid.org/0000-0002-6601-2165]
comment: Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round.
xref: RO:0015011

[Typedef]
id: has_developmental_contribution_from
name: has developmental contribution from
namespace: uberon
def: "x has developmental contribution from y iff x has some part z such that z develops from y" []
xref: RO:0002254
property_value: IAO:0000112 "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
domain: UBERON:0001062 ! anatomical entity
range: UBERON:0001062 ! anatomical entity
holds_over_chain: has_part develops_from
is_a: developmentally_preceded_by ! developmentally preceded by
inverse_of: developmentally_contributes_to ! developmentally contributes to

[Typedef]
id: has_developmental_potential_involving
name: has developmental potential involving
def: "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction)." []
xref: RO:0002384
property_value: IAO:0000114 IAO:0000428
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
domain: UBERON:0001062 ! anatomical entity
range: UBERON:0001062 ! anatomical entity
is_a: developmentally_related_to ! developmentally related to

[Typedef]
id: has_disposition
name: has disposition
def: "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence" []
xref: RO:0000091
domain: BFO:0000004 ! independent continuant
range: BFO:0000016 ! disposition
is_a: has_characteristic ! has characteristic
inverse_of: disposition_of ! disposition of

[Typedef]
id: has_effector_activity
name: has effector activity
def: "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity." [GOC:dos]
def: "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity." [https://orcid.org/0000-0002-7073-9172]
comment: This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations.
xref: RO:0002025
is_functional: true
is_a: has_component_activity ! has component activity
created_by: dos
created_by: https://orcid.org/0000-0002-7073-9172
creation_date: 2017-09-22T14:14:36Z

[Typedef]
id: has_end_location
name: has end location
def: "x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y" []
subset: ro-eco
xref: RO:0002232
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "ends with process that occurs in" xsd:string
domain: BFO:0000015 ! process
range: BFO:0000004 ! independent continuant
holds_over_chain: ends_with occurs_in
is_a: has_part_that_occurs_in ! has part that occurs in

[Typedef]
id: has_function
name: has function
def: "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence" []
xref: RO:0000085
property_value: editor_note "A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists." xsd:string
property_value: IAO:0000112 "this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)" xsd:string
property_value: IAO:0000118 "has_function" xsd:string
domain: BFO:0000004 ! independent continuant
range: BFO:0000034 ! function
is_a: has_characteristic ! has characteristic

[Typedef]
id: has_gene_template
name: has_gene_template
namespace: protein
def: "See document https://docs.google.com/document/d/15iVMtMyYbQSlvUDgn2XUaDzpwkB0USZI for full definition." [PRO:DAN]
is_transitive: false
is_a: RO:0002330

[Typedef]
id: has_input
name: has input
def: "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
subset: ro-eco
xref: RO:0002233
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "consumes" xsd:string
property_value: seeAlso "https://wiki.geneontology.org/Has_input" xsd:anyURI
domain: BFO:0000015 ! process
holds_over_chain: starts_with has_input
is_a: has_participant ! has participant
inverse_of: input_of ! input of

[Typedef]
id: has_member
name: has member
namespace: uberon
def: "has member is a mereological relation between a collection and an item." []
xref: RO:0002351
property_value: IAO:0000119 "SIO" xsd:string
property_value: RO:0001900 RO:0001901
is_a: has_part ! has part

[Typedef]
id: has_muscle_antagonist
name: has muscle antagonist
namespace: uberon
def: "m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position." []
xref: RO:0002568
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "Wikipedia:Antagonist_(muscle)" xsd:string
is_a: biomechanically_related_to ! biomechanically related to

[Typedef]
id: has_muscle_insertion
name: has muscle insertion
namespace: uberon
def: "m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone." []
xref: RO:0002373
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "Wikipedia:Insertion_(anatomy)" xsd:string
property_value: seeAlso http://dbpedia.org/property/insertion
domain: UBERON:0000061 {IAO:0000116="We need to import uberon muscle into RO to use as a stricter domain constraint"} ! anatomical structure
is_a: attaches_to ! attached to
is_a: biomechanically_related_to ! biomechanically related to

[Typedef]
id: has_muscle_origin
name: has muscle origin
namespace: uberon
def: "m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to." []
xref: RO:0002372
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "Wikipedia:Insertion_(anatomy)" xsd:string
property_value: seeAlso http://dbpedia.org/property/origin
domain: UBERON:0000061 {comment="We need to import uberon muscle to create a stricter domain constraint"} ! anatomical structure
is_a: attaches_to ! attached to
is_a: biomechanically_related_to ! biomechanically related to

[Typedef]
id: has_negative_regulatory_component_activity
name: has negative regulatory component activity
def: "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." []
comment: By convention GO molecular functions are classified by their effector function.  Internal regulatory functions are treated as components.  For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'.
xref: RO:0002014
is_a: has_regulatory_component_activity ! has regulatory component activity
is_a: negatively_regulated_by ! negatively regulated by
created_by: dos
created_by: https://orcid.org/0000-0002-7073-9172
creation_date: 2017-05-24T09:31:01Z

[Typedef]
id: has_ontology_root_term
name: has ontology root term
name: preferred_root
namespace: uberon
def: "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root" []
def: "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root." []
xref: IAO:0000700
property_value: IAO:0000111 "has ontology root term" xsd:string
property_value: IAO:0000117 "Nicolas Matentzoglu" xsd:string
is_metadata_tag: true

[Typedef]
id: has_output
name: has output
def: "p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
subset: ro-eco
xref: RO:0002234
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "produces" xsd:string
property_value: seeAlso "https://wiki.geneontology.org/Has_output" xsd:anyURI
holds_over_chain: ends_with has_output
is_a: has_participant ! has participant
inverse_of: output_of ! output of

[Typedef]
id: has_part
name: has part
name: has_part
namespace: protein
namespace: quality
namespace: spatial
namespace: uberon
def: "a core relation that holds between a whole and its part" []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: BFO:0000051
property_value: editor_note "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part." xsd:string
property_value: editor_note "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" xsd:string
property_value: editor_note "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'." xsd:string
property_value: IAO:0000111 "has part" xsd:string
property_value: IAO:0000112 "my body has part my brain (continuant parthood, two material entities)" xsd:string
property_value: IAO:0000112 "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)" xsd:string
property_value: IAO:0000112 "this year has part this day (occurrent parthood)" xsd:string
property_value: IAO:0000118 "has_part" xsd:string
property_value: RO:0001900 RO:0001901
is_transitive: true
is_a: overlaps ! overlaps

[Typedef]
id: has_part_structure_that_is_capable_of
name: has part structure that is capable of
def: "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" []
xref: RO:0002584
property_value: IAO:0000112 "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
holds_over_chain: has_part capable_of
is_a: causal_relation_between_material_entity_and_a_process ! causal relation between material entity and a process
is_a: functionally_related_to ! functionally related to

[Typedef]
id: has_part_that_occurs_in
name: has part that occurs in
def: "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c." []
subset: ro-eco
xref: RO:0002479
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
domain: BFO:0000003 ! occurrent
range: BFO:0000004 ! independent continuant
holds_over_chain: has_part occurs_in {RO:0002581="true"}

[Typedef]
id: has_participant
name: has participant
def: "a relation between a process and a continuant, in which the continuant is somehow involved in the process" []
xref: RO:0000057
property_value: editor_note "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time." xsd:string
property_value: http://purl.org/dc/elements/1.1/source "http://www.obofoundry.org/ro/#OBO_REL:has_participant" xsd:string
property_value: http://purl.org/dc/terms/source "http://www.obofoundry.org/ro/#OBO_REL:has_participant" xsd:string
property_value: IAO:0000111 "has participant" xsd:string
property_value: IAO:0000112 "this blood coagulation has participant this blood clot" xsd:string
property_value: IAO:0000112 "this investigation has participant this investigator" xsd:string
property_value: IAO:0000112 "this process has participant this input material (or this output material)" xsd:string
property_value: IAO:0000118 "has_participant" xsd:string
domain: BFO:0000003 ! occurrent
domain: BFO:0000015 ! process
range: BFO:0000002 ! continuant
holds_over_chain: has_part has_participant

[Typedef]
id: has_plasma_membrane_part
name: has plasma membrane part
def: "Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part." []
xref: RO:0002104
property_value: IAO:0000112 "Every B cell[CL_0000236] has plasma membrane part some immunoglobulin complex[GO_0019814]" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0001-9990-8331
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0003-1617-8244
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/19243617
property_value: RO:0001900 RO:0001901
domain: UBERON:0000465 ! material anatomical entity
range: UBERON:0000465 ! material anatomical entity
is_a: has_part ! has part
expand_expression_to: "BFO_0000051 some (GO_0005886 and BFO_0000051 some ?Y)" []

[Typedef]
id: has_positive_regulatory_component_activity
name: has positive regulatory component activity
def: "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." []
comment: By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components.  So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'.
xref: RO:0002015
is_a: has_regulatory_component_activity ! has regulatory component activity
is_a: positively_regulated_by ! positively regulated by
created_by: dos
created_by: https://orcid.org/0000-0002-7073-9172
creation_date: 2017-05-24T09:31:17Z

[Typedef]
id: has_potential_to_develop_into
name: has potential to develop into
namespace: uberon
def: "x has the potential to develop into y iff x develops into y or if x is capable of developing into y" []
xref: RO:0002387
property_value: IAO:0000114 IAO:0000428
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: has_developmental_potential_involving ! has developmental potential involving

[Typedef]
id: has_potential_to_developmentally_contribute_to
name: has potential to developmentally contribute to
namespace: uberon
def: "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y" []
xref: RO:0002385
property_value: IAO:0000114 IAO:0000428
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: has_developmental_potential_involving ! has developmental potential involving

[Typedef]
id: has_potential_to_developmentally_induce
name: has potential to developmentally induce
def: "x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y" []
xref: RO:0002386
property_value: IAO:0000114 IAO:0000428
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: has_developmental_potential_involving ! has developmental potential involving

[Typedef]
id: has_potential_to_directly_develop_into
name: has potential to directly develop into
def: "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y" []
xref: RO:0002388
property_value: IAO:0000114 IAO:0000428
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: has_potential_to_develop_into ! has potential to develop into

[Typedef]
id: has_primary_input
name: has primary input
def: "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c." [GOC:dph, GOC:kva, GOC:pt, https://orcid.org/0000-0002-6601-2165] {comment="PMID:27812932"}
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
xref: RO:0004009
is_a: has_input ! has input
is_a: has_primary_input_or_output ! has primary input or output
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-12-13T11:26:56Z

[Typedef]
id: has_primary_input_or_output
name: has primary input or output
def: "p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c." []
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
xref: RO:0004007
is_a: has_participant ! has participant
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-12-13T11:26:17Z

[Typedef]
id: has_primary_output
name: has primary output
def: "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c." [GOC:dph, GOC:kva, GOC:pt, https://orcid.org/0000-0002-6601-2165] {comment="PMID:27812932"}
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
xref: RO:0004008
is_a: has_output ! has output
is_a: has_primary_input_or_output ! has primary input or output
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-12-13T11:26:32Z

[Typedef]
id: has_quality
name: has quality
name: has_quality
namespace: protein
namespace: uberon
def: "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence" []
xref: RO:0000086
property_value: editor_note "A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist." xsd:string
property_value: IAO:0000112 "this apple has quality this red color" xsd:string
property_value: IAO:0000118 "has_quality" xsd:string
range: BFO:0000019 ! quality
is_transitive: false
is_a: has_characteristic ! has characteristic

[Typedef]
id: has_regulatory_component_activity
name: has regulatory component activity
def: "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." []
xref: RO:0002013
is_a: has_component_activity ! has component activity
is_a: regulated_by ! regulated by
created_by: dos
created_by: https://orcid.org/0000-0002-7073-9172
creation_date: 2017-05-24T09:30:46Z

[Typedef]
id: has_role
name: has role
def: "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence" []
xref: RO:0000087
property_value: editor_note "A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists." xsd:string
property_value: IAO:0000112 "this person has role this investigator role (more colloquially: this person has this role of investigator)" xsd:string
property_value: IAO:0000118 "has_role" xsd:string
domain: BFO:0000004 ! independent continuant
range: BFO:0000023 ! role
is_a: has_characteristic ! has characteristic

[Typedef]
id: has_skeleton
name: has skeleton
namespace: uberon
def: "A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision." []
xref: RO:0002551
property_value: curator_notes "The skeleton of a structure may be a true skeleton (for example, the bony skeleton of a hand) or any kind of support framework (the hydrostatic skeleton of a sea star, the exoskeleton of an insect, the cytoskeleton of a cell)." xsd:string
property_value: IAO:0000112 "Forelimb SubClassOf has_skeleton some 'Forelimb skeleton'" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "has supporting framework" xsd:string
domain: UBERON:0000061 ! anatomical structure
domain: UBERON:0000475 ! organism subdivision
range: UBERON:0000465 {IAO:0000116="This should be to a more restricted class, but not the Uberon class may be too restricted since it is a composition-based definition of skeleton rather than functional."} ! material anatomical entity
range: UBERON:0010912 ! subdivision of skeleton
is_a: has_part ! has part
inverse_of: skeleton_of ! skeleton of
is_asymmetric: true

[Typedef]
id: has_soma_location
name: has soma location
def: "Relation between a neuron and a material anatomical entity that its soma is part of." []
xref: RO:0002100
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: RO:0001900 RO:0001901
domain: CL:0000540 ! neuron
range: UBERON:0000465 ! material anatomical entity
is_a: overlaps ! overlaps
transitive_over: part_of ! part_of
expand_expression_to: "BFO_0000051 some (\n   GO_0043025 and   BFO_0000050 some ?Y)" []

[Typedef]
id: has_start_location
name: has start location
def: "x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y" []
subset: ro-eco
xref: RO:0002231
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "starts with process that occurs in" xsd:string
domain: BFO:0000015 ! process
range: BFO:0000004 ! independent continuant
holds_over_chain: starts_with occurs_in
is_a: has_part_that_occurs_in ! has part that occurs in

[Typedef]
id: has_target_end_location
name: has target end location
def: "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002339
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: results_in_transport_to_from_or_in ! results in transport to from or in
transitive_over: part_of ! part_of

[Typedef]
id: has_target_start_location
name: has target start location
def: "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002338
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: results_in_transport_to_from_or_in ! results in transport to from or in
transitive_over: part_of ! part_of

[Typedef]
id: helper_property_(not_for_use_in_curation)
name: helper property (not for use in curation)
xref: RO:0002464
property_value: curator_notes "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165

[Typedef]
id: homologous_to
name: shares ancestor with
namespace: uberon
def: "two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a." []
comment: VBO calls this homologous_to
xref: RO:0002158
property_value: curator_notes "Consider obsoleting and merging with child relation, 'in homology relationship with'" xsd:string
property_value: IAO:0000114 IAO:0000125
is_symmetric: true
is_transitive: true
is_a: evolutionarily_related_to ! evolutionarily related to

[Typedef]
id: immediate_transformation_of
name: immediate transformation of
namespace: uberon
def: "x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t" []
xref: RO:0002495
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: RO:0002575 RO:0002494
is_a: directly_develops_from ! directly develops from
is_a: transformation_of ! transformation of

[Typedef]
id: immediately_causally_downstream_of
name: immediately causally downstream of
xref: RO:0002405
property_value: IAO:0000114 IAO:0000428
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: causally_downstream_of ! causally downstream of
is_a: immediately_preceded_by ! immediately preceded by
inverse_of: immediately_causally_upstream_of ! immediately causally upstream of

[Typedef]
id: immediately_causally_upstream_of
name: immediately causally upstream of
def: "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." []
xref: RO:0002412
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: RO:0002575 RO:0002411
is_a: causally_upstream_of ! causally upstream of
is_a: immediately_precedes ! immediately precedes

[Typedef]
id: immediately_deep_to
name: immediately deep to
namespace: spatial
namespace: uberon
def: "x immediately deep to y iff x deep_to y and x is contiguous with y." [BSPO:curators]
xref: BSPO:0001107
is_a: deep_to ! deep to
inverse_of: immediately_superficial_to ! immediately superficial to

[Typedef]
id: immediately_preceded_by
name: immediately preceded by
namespace: uberon
comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)
xref: RO:0002087
property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string
property_value: IAO:0000118 "starts_at_end_of" xsd:string
holds_over_chain: starts_with ends_with
is_a: preceded_by ! preceded by
inverse_of: immediately_precedes ! immediately precedes

[Typedef]
id: immediately_precedes
name: immediately precedes
comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)
subset: ro-eco
xref: RO:0002090
property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: IAO:0000118 "ends_at_start_of" xsd:string
property_value: IAO:0000118 "meets" xsd:string
property_value: RO:0002575 BFO:0000063
holds_over_chain: ends_with starts_with
is_a: precedes ! precedes

[Typedef]
id: immediately_superficial_to
name: immediately superficial to
namespace: spatial
namespace: uberon
def: "x immediately superficial to y iff x superficial to y and x is contiguous with y." [BSPO:curators]
xref: BSPO:0015014
property_value: seeAlso https://github.com/obophenotype/uberon/issues/2453
is_a: adjacent_to ! adjacent to
is_a: superficial_to ! superficial to

[Typedef]
id: in_anterior_side_of
name: in anterior side of
namespace: spatial
namespace: uberon
def: "X anterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the anterior portion." [BSPO:PATO_mtg_2009]
xref: BSPO:0000123
is_a: part_of ! part_of

[Typedef]
id: in_branching_relationship_with
name: in branching relationship with
def: "A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network." []
xref: RO:0002375
property_value: curator_notes "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships" xsd:string
property_value: curator_notes "This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves)" xsd:string
property_value: IAO:0000114 IAO:0000428
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: RO:0004036 BFO:0000050
property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/branching_part_of.png
property_value: seeAlso "https://github.com/obophenotype/uberon/issues/170" xsd:anyURI
domain: BFO:0000040 ! material entity
range: BFO:0000040 ! material entity
is_a: mereotopologically_related_to ! mereotopologically related to

[Typedef]
id: in_distal_side_of
name: in distal side of
namespace: spatial
namespace: uberon
def: "x in distal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the distal portion." [BSPO:PATO_mtg_2009]
xref: BSPO:0000125
is_a: part_of ! part_of

[Typedef]
id: in_dorsal_side_of
name: in dorsal side of
namespace: spatial
namespace: uberon
def: "X dorsal side of Y <=> if Y is subdivided into two dorsal and ventral portions, X is part of the dorsal portion." [BSPO:cjm]
xref: BSPO:0015101
is_a: part_of ! part_of

[Typedef]
id: in_lateral_side_of
name: in lateral side of
namespace: spatial
namespace: uberon
def: "X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure" [UBERON:cjm]
xref: BSPO:0000126
property_value: seeAlso https://github.com/obophenotype/uberon/issues/2453
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI
is_a: part_of ! part_of

[Typedef]
id: in_left_side_of
name: in left side of
namespace: spatial
namespace: uberon
def: "X in left side of Y <=> if Y is subdivided into two left and right portions, X is part of the left portion." [BSPO:PATO_mtg_2009]
xref: BSPO:0000120
xref: NCIT:C25229
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI
is_a: in_lateral_side_of ! in lateral side of
disjoint_from: in_right_side_of ! in right side of

[Typedef]
id: in_posterior_side_of
name: in posterior side of
namespace: spatial
namespace: uberon
def: "X posterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the posterior portion." [BSPO:PATO_mtg_2009]
xref: BSPO:0000122
is_a: part_of ! part_of

[Typedef]
id: in_proximal_side_of
name: in proximal side of
namespace: spatial
namespace: uberon
def: "x in proximal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the proximal portion." [BSPO:PATO_mtg_2009]
xref: BSPO:0000124
is_a: part_of ! part_of

[Typedef]
id: in_right_side_of
name: in right side of
namespace: spatial
namespace: uberon
def: "X in right side of Y <=> if Y is subdivided into two left and right portions, X is part of the right portion." [BSPO:PATO_mtg_2009]
xref: BSPO:0000121
xref: NCIT:C25228
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI
is_a: in_lateral_side_of ! in lateral side of

[Typedef]
id: in_taxon
name: in taxon
namespace: uberon
def: "x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed." []
comment: Connects a biological entity to its taxon of origin.
subset: ro-eco
xref: RO:0002162
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0001-9227-417X
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/17921072
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20973947
property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Taxon-constraints
holds_over_chain: attaches_to in_taxon
holds_over_chain: capable_of in_taxon
holds_over_chain: connected_to in_taxon
holds_over_chain: connects in_taxon
holds_over_chain: continuous_with in_taxon
holds_over_chain: developmentally_induced_by in_taxon
holds_over_chain: develops_from in_taxon
holds_over_chain: develops_from_part_of in_taxon
holds_over_chain: existence_ends_during in_taxon
holds_over_chain: existence_starts_during in_taxon
holds_over_chain: extends_fibers_into in_taxon
holds_over_chain: has_developmental_contribution_from in_taxon
holds_over_chain: has_part in_taxon
holds_over_chain: has_potential_to_develop_into in_taxon
holds_over_chain: innervated_by in_taxon
holds_over_chain: overlaps in_taxon
holds_over_chain: part_of in_taxon
holds_over_chain: produced_by in_taxon
holds_over_chain: produces in_taxon
holds_over_chain: results_in_developmental_progression_of in_taxon
holds_over_chain: supplies in_taxon
is_a: evolutionarily_related_to ! evolutionarily related to

[Typedef]
id: increased_in_magnitude_relative_to
name: obsolete increased_in_magnitude_relative_to
namespace: quality
def: "OBSOLETE. q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [PATOC:CJM]
comment: Refer to https://github.com/pato-ontology/pato/issues/454. This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'.
domain: PATO:0000001 ! quality
range: PATO:0000001 ! quality
is_transitive: true
is_obsolete: true
replaced_by: RO:0015007

[Typedef]
id: indirectly_causally_upstream_of
name: indirectly causally upstream of
def: "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." []
xref: RO:0012011
is_a: causally_upstream_of ! causally upstream of
created_by: https://orcid.org/0000-0003-1813-6857
created_by: pg
creation_date: 2022-09-26T06:07:17Z

[Typedef]
id: indirectly_negatively_regulates
name: indirectly negatively regulates
def: "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." []
xref: RO:0002409
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "indirectly inhibits" xsd:string
property_value: RO:0002579 RO:0002212
property_value: seeAlso "https://wiki.geneontology.org/Indirectly_negatively_regulates" xsd:anyURI
holds_over_chain: directly_negatively_regulates directly_negatively_regulates
holds_over_chain: directly_negatively_regulates indirectly_negatively_regulates
is_transitive: true
is_a: indirectly_regulates ! indirectly regulates
is_a: negatively_regulates ! negatively regulates
transitive_over: directly_negatively_regulates ! directly negatively regulates

[Typedef]
id: indirectly_positively_regulates
name: indirectly positively regulates
def: "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." []
xref: RO:0002407
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "indirectly activates" xsd:string
property_value: RO:0002579 RO:0002213
property_value: seeAlso "https://wiki.geneontology.org/Indirectly_positively_regulates" xsd:anyURI
holds_over_chain: directly_positively_regulates directly_positively_regulates
holds_over_chain: directly_positively_regulates indirectly_positively_regulates
holds_over_chain: indirectly_negatively_regulates indirectly_negatively_regulates
is_transitive: true
is_a: indirectly_regulates ! indirectly regulates
is_a: positively_regulates ! positively regulates
transitive_over: directly_positively_regulates ! directly positively regulates

[Typedef]
id: indirectly_regulates
name: indirectly regulates
def: "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." []
xref: RO:0012012
is_a: indirectly_causally_upstream_of ! indirectly causally upstream of
is_a: regulates ! regulates
created_by: https://orcid.org/0000-0003-1813-6857
created_by: pg
creation_date: 2022-09-26T06:08:01Z

[Typedef]
id: indirectly_supplies
name: indirectly_supplies
namespace: uberon
def: "a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s." []
property_value: editor_note "add to RO" xsd:string
holds_over_chain: has_branching_part indirectly_supplies
holds_over_chain: has_branching_part supplies
is_transitive: true

[Typedef]
id: innervated_by
name: innervated_by
namespace: uberon
xref: RO:0002005
property_value: http://purl.org/spar/cito/citesAsAuthority "http://www.ncbi.nlm.nih.gov/pubmed/22402613" xsd:anyURI
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
domain: UBERON:0000061 ! anatomical structure
range: UBERON:0000122 ! neuron projection bundle
inverse_of: innervates ! innervates
transitive_over: branching_part_of ! branching part of

[Typedef]
id: innervates
name: innervates
namespace: uberon
def: "Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input.\nT innervates some R\nExpands_to: T has_fasciculating_neuron_projection that synapse_in some R." []
xref: RO:0002134
property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: RO:0001900 RO:0001901
domain: UBERON:0000122 ! neuron projection bundle
transitive_over: part_of ! part_of
expand_expression_to: "RO_0002132 some (GO_0043005 that (RO_0002131 some (GO_0045202 that BFO_0000050 some Y?)))" []

[Typedef]
id: input_of
name: input of
namespace: uberon
def: "inverse of has input" []
subset: ro-eco
subset: RO:0002259
xref: RO:0002352
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: functionally_related_to ! functionally related to
is_a: participates_in ! participates in

[Typedef]
id: interaction_relation_helper_property
name: interaction relation helper property
xref: RO:0002563
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29
property_value: seeAlso "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/" xsd:anyURI
is_a: helper_property_(not_for_use_in_curation) ! helper property (not for use in curation)

[Typedef]
id: interacts_with
name: interacts with
def: "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." []
subset: ro-eco
synonym: "in pairwise interaction with" EXACT []
xref: RO:0002434
property_value: closeMatch "http://purl.obolibrary.org/obo/MI_0914" xsd:anyURI
property_value: curator_notes "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules." xsd:string
property_value: editor_note "Considering relabeling as 'pairwise interacts with'" xsd:anyURI
property_value: editor_note "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: seeAlso "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/" xsd:anyURI
domain: BFO:0000040 ! material entity
range: BFO:0000040 ! material entity
is_symmetric: true

[Typedef]
id: intersects_midsagittal_plane_of
name: intersects midsagittal plane of
namespace: spatial
namespace: uberon
def: "X intersects median plane of iff X crosses the midine plane of Y." []
xref: BSPO:0005001
is_a: part_of ! part_of

[Typedef]
id: involved_in
name: involved in
def: "c involved_in p if and only if c enables some process p', and p' is part of p" []
xref: RO:0002331
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "actively involved in" xsd:string
property_value: IAO:0000118 "enables part of" xsd:string
property_value: seeAlso "https://wiki.geneontology.org/Involved_in" xsd:anyURI
property_value: seeAlso Involved:in
holds_over_chain: enables part_of
is_a: involved_in_or_involved_in_regulation_of ! involved in or involved in regulation of
is_a: participates_in ! participates in
transitive_over: part_of ! part_of

[Typedef]
id: involved_in_negative_regulation_of
name: involved in negative regulation of
def: "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" []
xref: RO:0002430
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: RO:0004050 RO:0002428
holds_over_chain: enables negatively_regulates
holds_over_chain: involved_in negatively_regulates
is_a: involved_in_regulation_of ! involved in regulation of

[Typedef]
id: involved_in_or_involved_in_regulation_of
name: involved in or involved in regulation of
def: "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" []
xref: RO:0002431
property_value: editor_note "OWL does not allow defining object properties via a Union" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "involved in or reguates" xsd:string
is_a: acts_upstream_of_or_within ! acts upstream of or within
is_a: causal_agent_in_process ! causal agent in process
is_a: functionally_related_to ! functionally related to

[Typedef]
id: involved_in_positive_regulation_of
name: involved in positive regulation of
def: "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" []
xref: RO:0002429
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: RO:0004049 RO:0002428
holds_over_chain: enables positively_regulates
holds_over_chain: involved_in positively_regulates
is_a: involved_in_regulation_of ! involved in regulation of

[Typedef]
id: involved_in_regulation_of
name: involved in regulation of
def: "c involved in regulation of p if c is involved in some p' and p' regulates some p" []
xref: RO:0002428
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
holds_over_chain: enables regulates
holds_over_chain: involved_in regulates
is_a: acts_upstream_of ! acts upstream of
is_a: involved_in_or_involved_in_regulation_of ! involved in or involved in regulation of

[Typedef]
id: is_active_in
name: is active in
def: "c executes activity in d if and only if c enables p and p occurs_in d.  Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure." [https://orcid.org/0000-0002-6601-2165, https://orcid.org/0000-0002-7073-9172]
synonym: "enables activity in" EXACT []
xref: RO:0002432
property_value: IAO:0000112 "A protein that enables activity in a cytosol." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "executes activity in" xsd:string
property_value: seeAlso "https://wiki.geneontology.org/Is_active_in" xsd:anyURI
holds_over_chain: enables occurs_in {RO:0002581="true"}
is_a: functionally_related_to ! functionally related to
is_a: overlaps ! overlaps

[Typedef]
id: is_kinase_activity
name: is kinase activity
xref: RO:0002481
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: molecular_interaction_relation_helper_property ! molecular interaction relation helper property

[Typedef]
id: layer_part_of
name: layer part of
namespace: uberon
is_a: part_of ! part_of

[Typedef]
id: left_of
name: left of
namespace: spatial
def: "Closer to the left side of the organism. Example: The dorsal fin is right of the left pectoral fin, but is left of the right eye. On the type level: X left of Y <=> every instance x of X is left of some instance y of Y, and there exists some organism o such that x part of o and y part of o." [BSPO:cjm]
xref: BSPO:0000110
is_transitive: true
inverse_of: right_of ! right of

[Typedef]
id: located_in
name: located in
name: located_in
namespace: protein
namespace: uberon
def: "a relation between two independent continuants, the target and the location, in which the target is entirely within the location" []
subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
xref: RO:0001025
property_value: editor_note "Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1.    Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus" xsd:string
property_value: editor_note "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" xsd:string
property_value: http://purl.org/dc/elements/1.1/source "http://www.obofoundry.org/ro/#OBO_REL:located_in" xsd:string
property_value: http://purl.org/dc/terms/source "http://www.obofoundry.org/ro/#OBO_REL:located_in" xsd:string
property_value: IAO:0000111 "located in" xsd:string
property_value: IAO:0000112 "my brain is located in my head" xsd:string
property_value: IAO:0000112 "this rat is located in this cage" xsd:string
property_value: IAO:0000118 "located_in" xsd:string
property_value: RO:0001900 RO:0001901
property_value: seeAlso "https://wiki.geneontology.org/Located_in" xsd:anyURI
domain: BFO:0000004 {IAO:0000116="This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation."} ! independent continuant
range: BFO:0000004 {IAO:0000116="This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation."} ! independent continuant
is_transitive: true
transitive_over: part_of ! part_of

[Typedef]
id: location_of
name: location of
namespace: uberon
def: "a relation between two independent continuants, the location and the target, in which the target is entirely within the location" []
xref: RO:0001015
property_value: editor_note "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" xsd:string
property_value: IAO:0000111 "is location of" xsd:string
property_value: IAO:0000112 "my head is the location of my brain" xsd:string
property_value: IAO:0000112 "this cage is the location of this rat" xsd:string
property_value: IAO:0000118 "location_of" xsd:string
property_value: RO:0001900 RO:0001901
is_transitive: true
inverse_of: located_in ! located in

[Typedef]
id: lumen_of
name: lumen of
namespace: uberon
def: "x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull." []
subset: ro-eco
xref: RO:0002571
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 https://orcid.org/0000-0002-6601-2165
range: BFO:0000040 ! material entity
is_a: part_of ! part_of

[Typedef]
id: luminal_space_of
name: luminal space of
namespace: uberon
def: "s is luminal space of x iff s is lumen_of x and s is an immaterial entity" []
subset: ro-eco
xref: RO:0002572
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
domain: BFO:0000141 ! immaterial entity
is_a: lumen_of ! lumen of

[Typedef]
id: member_of
name: member of
def: "is member of is a mereological relation between a item and a collection." []
xref: RO:0002350
property_value: IAO:0000112 "An organism that is a member of a population of organisms" xsd:string
property_value: IAO:0000118 "is member of" xsd:string
property_value: IAO:0000118 "member part of" xsd:string
property_value: IAO:0000119 "SIO" xsd:string
property_value: RO:0001900 RO:0001901
is_a: part_of ! part_of
inverse_of: has_member ! has member

[Typedef]
id: mereotopologically_related_to
name: mereotopologically related to
def: "A mereological relationship or a topological relationship" []
xref: RO:0002323
property_value: curator_notes "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: RO:0001900 RO:0001901

[Typedef]
id: molecular_interaction_relation_helper_property
name: molecular interaction relation helper property
xref: RO:0002564
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: interaction_relation_helper_property ! interaction relation helper property

[Typedef]
id: molecularly_interacts_with
name: molecularly interacts with
def: "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." []
xref: RO:0002436
property_value: closeMatch "http://purl.obolibrary.org/obo/MI_0915" xsd:anyURI
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "binds" xsd:string
property_value: IAO:0000118 "molecularly binds with" xsd:string
property_value: seeAlso ECO:0000353
is_symmetric: true
is_a: interacts_with ! interacts with

[Typedef]
id: negatively_regulated_by
name: negatively regulated by
def: "inverse of negatively regulates" []
subset: RO:0002259
xref: RO:0002335
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: regulated_by ! regulated by

[Typedef]
id: negatively_regulates
name: negatively regulates
def: "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002212
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
property_value: IAO:0000589 "negatively regulates (process to process)" xsd:string
property_value: RO:0004050 RO:0002211
holds_over_chain: ends_with negatively_regulates
is_a: causally_upstream_of,_negative_effect ! causally upstream of, negative effect
is_a: regulates ! regulates
inverse_of: negatively_regulated_by ! negatively regulated by

[Typedef]
id: negatively_regulates_characteristic
name: negatively regulates characteristic
def: "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C." []
xref: RO:0019002
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-8688-6599
holds_over_chain: negatively_regulates positively_regulates_characteristic
holds_over_chain: positively_regulates negatively_regulates_characteristic
is_a: regulates_characteristic ! regulates characteristic

[Typedef]
id: obsolete_contains
name: contains
name: obsolete contains
namespace: uberon
xref: RO:0001019
property_value: IAO:0000111 "contains" xsd:string
property_value: seeAlso https://github.com/oborel/obo-relations/issues/693
is_obsolete: true

[Typedef]
id: occurs_across
name: occurs across
def: "A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization." []
xref: RO:0002021
is_a: has_part_that_occurs_in ! has part that occurs in
created_by: https://orcid.org/0000-0002-7073-9172
creation_date: 2017-07-20T17:19:37Z

[Typedef]
id: occurs_in
name: occurs in
def: "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t" []
comment: Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: BFO:0000066
property_value: IAO:0000111 "occurs in" xsd:string
property_value: IAO:0000118 "occurs_in" xsd:string
property_value: IAO:0000118 "unfolds in" xsd:string
property_value: IAO:0000118 "unfolds_in" xsd:string
property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl
property_value: seeAlso "https://wiki.geneontology.org/Occurs_in" xsd:anyURI
domain: BFO:0000003 ! occurrent
range: BFO:0000004 ! independent continuant
holds_over_chain: part_of occurs_in
inverse_of: contains_process ! contains process
transitive_over: part_of ! part_of

[Typedef]
id: only_in_taxon
name: only in taxon
name: only_in_taxon
namespace: protein
namespace: uberon
def: "U only_in_taxon T: U is a feature found in only in organisms of species of taxon T. The feature cannot be found in an organism of any species outside of (not subsumed by) that taxon. Down-propagates in U hierarchy, up-propagates in T hierarchy (species taxonomy). Implies applicable_to_taxon." [ROC:Waclaw]
def: "x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z." []
comment: Down-propagates. The original name for this in the paper is 'specific_to'. Applicable to genes because some genes are lost in sub-species (strains) of a species.
synonym: "never_outside_taxon" EXACT []
synonym: "specific_to" EXACT []
synonym: "specific_to_taxon" EXACT []
xref: RO:0002160
property_value: editor_note "The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g.\n\n 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria" xsd:string
property_value: IAO:0000112 "lactation SubClassOf 'only in taxon' some 'Mammalia'" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/17921072
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20973947
property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Taxon-constraints
is_transitive: false
is_a: in_taxon ! in taxon

[Typedef]
id: opposite_to
name: opposite to
namespace: spatial
def: "Direcly opposite to. i.e. on the opposite side through the axis." [BSPO:cjm]
xref: BSPO:0000113

[Typedef]
id: orthogonal_to
name: orthogonal to
namespace: spatial
def: "crossing at right angles" [BSPO:cjm]
xref: BSPO:0015005
domain: BSPO:0000010 ! anatomical axis
range: BSPO:0000400 ! anatomical plane

[Typedef]
id: output_of
name: output of
name: output_of
namespace: protein
namespace: uberon
def: "inverse of has output" []
subset: ro-eco
subset: RO:0002259
xref: RO:0002353
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_transitive: false
is_a: functionally_related_to ! functionally related to
is_a: participates_in ! participates in

[Typedef]
id: overlaps
name: overlaps
namespace: spatial
namespace: uberon
def: "x overlaps y if and only if there exists some z such that x has part z and z part of y" []
def: "x overlaps y iff they have some part in common." [BSPO:cjm]
comment: "(forall (x y) (iff (overlaps x y) (exists (z) (and (part of z x) (part of z y)))))" CLIF []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_gocam
subset: ro-eco
xref: RO:0002131
property_value: IAO:0000114 IAO:0000125
property_value: RO:0001900 RO:0001901
holds_over_chain: has_part overlaps
holds_over_chain: has_part part_of {RO:0002582="true"}
holds_over_chain: part_of part_of
is_symmetric: true
is_a: mereotopologically_related_to ! mereotopologically related to
transitive_over: part_of ! part_of
expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)" []

[Typedef]
id: part_of
name: part of
name: part_of
namespace: protein
namespace: quality
namespace: spatial
namespace: uberon
def: "a core relation that holds between a part and its whole" []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: BFO:0000050
property_value: editor_note "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other." xsd:string
property_value: editor_note "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" xsd:string
property_value: editor_note "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'." xsd:string
property_value: IAO:0000111 "is part of" xsd:string
property_value: IAO:0000112 "my brain is part of my body (continuant parthood, two material entities)" xsd:string
property_value: IAO:0000112 "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)" xsd:string
property_value: IAO:0000112 "this day is part of this year (occurrent parthood)" xsd:string
property_value: IAO:0000118 "part_of" xsd:string
property_value: RO:0001900 RO:0001901
property_value: RO:0040042 BFO:0000002
property_value: RO:0040042 BFO:0000003
property_value: RO:0040042 BFO:0000004
property_value: RO:0040042 BFO:0000017
property_value: RO:0040042 BFO:0000019
property_value: RO:0040042 BFO:0000020
property_value: RO:0040042 BFO:0000031
property_value: seeAlso http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections
property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:PartOf
property_value: seeAlso "http://www.obofoundry.org/ro/#OBO_REL:part_of" xsd:string
property_value: seeAlso "https://wiki.geneontology.org/Part_of" xsd:anyURI
is_transitive: true
is_a: overlaps ! overlaps
inverse_of: has_part ! has part

[Typedef]
id: part_of_developmental_precursor_of
name: part of developmental precursor of
xref: RO:0002287
property_value: IAO:0000112 "'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
holds_over_chain: part_of directly_develops_into
is_a: developmentally_succeeded_by ! developmentally succeeded by

[Typedef]
id: part_of_structure_that_is_capable_of
name: part of structure that is capable of
def: "this relation holds between c and p when c is part of some c', and c' is capable of p." []
xref: RO:0002329
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "false" xsd:boolean
holds_over_chain: part_of capable_of {RO:0002581="true"}
is_a: functionally_related_to ! functionally related to

[Typedef]
id: participates_in
name: participates in
namespace: uberon
def: "a relation between a continuant and a process, in which the continuant is somehow involved in the process" []
xref: RO:0000056
property_value: IAO:0000111 "participates in" xsd:string
property_value: IAO:0000112 "this blood clot participates in this blood coagulation" xsd:string
property_value: IAO:0000112 "this input material (or this output material) participates in this process" xsd:string
property_value: IAO:0000112 "this investigator participates in this investigation" xsd:string
property_value: IAO:0000118 "participates_in" xsd:string
domain: BFO:0000002 ! continuant
range: BFO:0000003 ! occurrent
inverse_of: has_participant ! has participant

[Typedef]
id: passes_through
name: passes through
namespace: spatial
def: "Intersects at two points." [BSPO:cjm]
xref: BSPO:0015006
domain: BSPO:0000010 ! anatomical axis

[Typedef]
id: phosphorylates
name: phosphorylates
xref: RO:0002447
property_value: editor_note "Axiomatization to GO to be added later" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y." xsd:string
is_a: molecularly_interacts_with ! molecularly interacts with

[Typedef]
id: positively_regulated_by
name: positively regulated by
def: "inverse of positively regulates" []
subset: RO:0002259
xref: RO:0002336
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: regulated_by ! regulated by

[Typedef]
id: positively_regulates
name: positively regulates
def: "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002213
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
property_value: IAO:0000589 "positively regulates (process to process)" xsd:string
property_value: RO:0004049 RO:0002211
holds_over_chain: ends_with positively_regulates
holds_over_chain: negatively_regulates negatively_regulates
is_transitive: true
is_a: causally_upstream_of,_positive_effect ! causally upstream of, positive effect
is_a: regulates ! regulates
inverse_of: positively_regulated_by ! positively regulated by

[Typedef]
id: positively_regulates_characteristic
name: positively regulates characteristic
def: "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C." []
xref: RO:0019001
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-8688-6599
holds_over_chain: positively_regulates positively_regulates_characteristic
is_a: regulates_characteristic ! regulates characteristic

[Typedef]
id: posterior_to
name: posterior to
namespace: spatial
namespace: uberon
def: "x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail." [BSPO:cjm]
synonym: "caudal to" NARROW vertebrate []
xref: BSPO:0000099
property_value: seeAlso FBcv:0000045
property_value: seeAlso FBql:00005864
is_transitive: true

[Typedef]
id: posteriorly_connected_to
name: posteriorly connected to
namespace: uberon
def: "x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern]
is_a: anterior_to ! anterior to
is_a: connected_to ! connected to

[Typedef]
id: preceded_by
name: preceded by
namespace: uberon
def: "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." []
subset: ro-eco
xref: BFO:0000062
property_value: editor_note "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C.    The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other." xsd:string
property_value: http://purl.org/dc/elements/1.1/source "http://www.obofoundry.org/ro/#OBO_REL:preceded_by" xsd:string
property_value: http://purl.org/dc/terms/source "http://www.obofoundry.org/ro/#OBO_REL:preceded_by" xsd:string
property_value: IAO:0000111 "preceded by" xsd:string
property_value: IAO:0000118 "is preceded by" xsd:string
property_value: IAO:0000118 "preceded_by" xsd:string
domain: BFO:0000003 ! occurrent
range: BFO:0000003 ! occurrent
holds_over_chain: part_of preceded_by
is_transitive: true
is_a: ends_after ! ends after
inverse_of: precedes ! precedes

[Typedef]
id: precedes
name: precedes
namespace: uberon
def: "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." []
subset: ro-eco
xref: BFO:0000063
property_value: IAO:0000111 "precedes" xsd:string
domain: BFO:0000003 ! occurrent
range: BFO:0000003 ! occurrent
holds_over_chain: part_of precedes
is_transitive: true
is_a: temporally_related_to ! temporally related to

[Typedef]
id: process_has_causal_agent
name: process has causal agent
def: "Inverse of 'causal agent in process'" []
xref: RO:0002608
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
is_a: causally_related_to ! causally related to

[Typedef]
id: produced_by
name: produced by
namespace: uberon
def: "a produced_by b iff some process that occurs_in b has_output a." []
subset: ro-eco
xref: RO:0003001
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737
domain: BFO:0000040 ! material entity
range: BFO:0000040 ! material entity

[Typedef]
id: produces
name: produces
namespace: uberon
def: "a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix." []
comment: Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue.
subset: ro-eco
xref: RO:0003000
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737
domain: BFO:0000040 ! material entity
range: BFO:0000040 ! material entity
inverse_of: produced_by ! produced by

[Typedef]
id: protects
name: protects
namespace: uberon

[Typedef]
id: proximal_to
name: proximal to
namespace: spatial
namespace: uberon
def: "x proximal to y iff x is closer to the point of attachment with the body than y." [BSPO:cjm]
comment: The elbow is proximal to the hand, but distal to the shoulder.
xref: BSPO:0000100
xref: NCIT:C25236
property_value: seeAlso FBcv:0000047
property_value: seeAlso FBql:00005868
is_transitive: true

[Typedef]
id: proximally_connected_to
name: proximally connected to
namespace: uberon
def: "x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern]
is_a: connected_to ! connected to
is_a: distal_to ! distal to
is_a: transitively_proximally_connected_to ! transitively proximally connected to

[Typedef]
id: proximalmost_part_of
name: proximalmost part of
namespace: spatial
namespace: uberon
def: "X proximalmost part of Y <=> X is in proximal side of Y and X is adjacent to the proximal boundary of Y" [https://orcid.org/0000-0002-6601-2165]
xref: BSPO:0001106
is_a: in_proximal_side_of ! in proximal side of

[Typedef]
id: quality_of
name: quality of
def: "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence" []
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.
xref: RO:0000080
property_value: editor_note "A quality inheres in its bearer at all times for which the quality exists." xsd:string
property_value: IAO:0000112 "this red color is a quality of this apple" xsd:string
property_value: IAO:0000118 "is quality of" xsd:string
property_value: IAO:0000118 "quality_of" xsd:string
is_a: characteristic_of ! characteristic of
inverse_of: has_quality ! has quality

[Typedef]
id: receives_input_from
name: receives input from
xref: RO:0002485
property_value: editor_note "See notes for inverse relation" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: connected_to ! connected to
inverse_of: sends_output_to ! sends output to

[Typedef]
id: regulated_by
name: regulated by
def: "inverse of regulates" []
subset: RO:0002259
xref: RO:0002334
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000589 "regulated by (processual)" xsd:string
domain: BFO:0000015 ! process
range: BFO:0000015 ! process
is_transitive: true
is_a: causally_downstream_of_or_within ! causally downstream of or within

[Typedef]
id: regulates
name: regulates
name: regulates (processual)
def: "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002211
property_value: curator_notes "Regulation precludes parthood; the regulatory process may not be within the regulated process." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0001-7476-6306
property_value: IAO:0000117 https://orcid.org/0000-0002-3837-8864
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "GO" xsd:string
property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations
property_value: IAO:0000589 "regulates (processual)" xsd:string
property_value: IAO:0000600 "false" xsd:boolean
domain: BFO:0000015 ! process
range: BFO:0000015 ! process
holds_over_chain: directly_regulates directly_regulates
holds_over_chain: ends_with regulates
is_transitive: true
is_a: causally_upstream_of ! causally upstream of
inverse_of: regulated_by ! regulated by
transitive_over: has_effector_activity ! has effector activity

[Typedef]
id: regulates_activity_of
name: regulates activity of
def: "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." []
xref: RO:0011002
property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431
domain: BFO:0000040 ! material entity
range: BFO:0000040 ! material entity
is_a: causally_influences ! causally influences

[Typedef]
id: regulates_characteristic
name: regulates characteristic
def: "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." []
xref: RO:0019000
property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-8688-6599
domain: BFO:0000015 ! process
range: PATO:0000001 ! quality
holds_over_chain: regulates regulates_characteristic
is_a: causally_related_to ! causally related to

[Typedef]
id: related_via_localization_to
name: related via localization to
def: "A relationship that holds via some process of localization" []
xref: RO:0002337
property_value: curator_notes "Do not use this relation directly. It is a grouping relation." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
domain: BFO:0000015 ! process
range: BFO:0000002 ! continuant

[Typedef]
id: relation_between_physical_entity_and_a_process_or_stage
name: relation between physical entity and a process or stage
xref: RO:0002487
property_value: curator_notes "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
domain: BFO:0000004 ! independent continuant
range: BFO:0000003 ! occurrent

[Typedef]
id: results_in_acquisition_of_features_of
name: results in acquisition of features of
def: "The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity" []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002315
property_value: IAO:0000112 "an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string
range: UBERON:0000061 ! anatomical structure
is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure
is_a: results_in_developmental_progression_of ! results in developmental progression of

[Typedef]
id: results_in_assembly_of
name: results in assembly of
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002588
is_a: results_in_formation_of_anatomical_entity ! results in formation of anatomical entity
is_a: results_in_organization_of ! results in organization of

[Typedef]
id: results_in_breakdown_of
name: results in breakdown of
def: "p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p" []
xref: RO:0002586
is_a: has_input ! has input

[Typedef]
id: results_in_changes_to_anatomical_or_cellular_structure
name: results in changes to anatomical or cellular structure
def: "p has anatomical participant c iff p has participant c, and c is an anatomical entity" []
xref: RO:0040036
is_a: has_participant ! has participant
created_by: https://orcid.org/0000-0002-6601-2165
creation_date: 2018-09-26T01:08:58Z

[Typedef]
id: results_in_development_of
name: results in development of
def: "p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002296
property_value: IAO:0000112 "every flower development (GO:0009908) results in development of some flower (PO:0009046)" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "http://www.geneontology.org/GO.doc.development.shtml" xsd:anyURI
is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure
is_a: results_in_developmental_progression_of ! results in developmental progression of

[Typedef]
id: results_in_developmental_progression_of
name: results in developmental progression of
def: "p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss)." []
xref: RO:0002295
property_value: editor_note "This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint." xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: seeAlso Ontology:extensions
domain: GO:0008150 ! biological process
range: UBERON:0001062 ! anatomical entity
is_a: developmentally_related_to ! developmentally related to

[Typedef]
id: results_in_disassembly_of
name: results in disassembly of
xref: RO:0002590
is_a: results_in_breakdown_of ! results in breakdown of
is_a: results_in_organization_of ! results in organization of

[Typedef]
id: results_in_distribution_of
name: results in distribution of
name: results_in_distribution_of
namespace: external
xref: GOREL:0002003

[Typedef]
id: results_in_fission_of
name: results in fission of
name: results_in_fission_of
namespace: external
xref: GOREL:0002004
is_a: has_participant ! has participant

[Typedef]
id: results_in_formation_of_anatomical_entity
name: results in formation of anatomical entity
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002297
property_value: IAO:0000112 "an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists." xsd:string
property_value: IAO:0000112 "every \"endocardial cushion formation\" (GO:0003272) results_in_formation_of some \"endocardial cushion\" (UBERON:0002062)" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string
is_a: has_output ! has output
is_a: results_in_developmental_progression_of ! results in developmental progression of
inverse_of: formed_as_result_of ! formed as result of

[Typedef]
id: results_in_fusion_of
name: results in fusion of
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0012008
is_a: results_in_organization_of ! results in organization of
created_by: https://orcid.org/0000-0003-1813-6857
creation_date: 2021-02-26T07:28:29Z

[Typedef]
id: results_in_growth_of
name: results in growth of
xref: RO:0002343
property_value: IAO:0000112 "'pollen tube growth' results_in growth_of some 'pollen tube'" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure
is_a: results_in_developmental_progression_of ! results in developmental progression of

[Typedef]
id: results_in_maturation_of
name: results in maturation of
def: "The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002299
property_value: IAO:0000112 " an annotation of gene X to cell maturation with results_in_maturation_of CL:0000057 (fibroblast) means that the fibroblast is mature at the end of the process" xsd:string
property_value: IAO:0000112 "bone maturation (GO:0070977) results_in_maturation_of bone (UBERON:0001474)" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string
is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure
is_a: results_in_developmental_progression_of ! results in developmental progression of

[Typedef]
id: results_in_morphogenesis_of
name: results in morphogenesis of
def: "The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002298
property_value: IAO:0000112 "an annotation of gene X to cell morphogenesis with results_in_morphogenesis_of CL:0000540 (neuron) means that at the end of the process an input neuron has attained its shape." xsd:string
property_value: IAO:0000112 "tongue morphogenesis (GO:0043587) results in morphogenesis of tongue (UBERON:0001723)" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string
is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure
is_a: results_in_developmental_progression_of ! results in developmental progression of

[Typedef]
id: results_in_movement_of
name: results in movement of
def: "Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c" []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
xref: RO:0002565
property_value: curator_notes "" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure

[Typedef]
id: results_in_organization_of
name: results in organization of
def: "p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c" []
xref: RO:0002592
is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure

[Typedef]
id: results_in_transport_across
name: results in transport across
def: "Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m." []
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
xref: RO:0002342
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: occurs_across ! occurs across
is_a: results_in_transport_to_from_or_in ! results in transport to from or in

[Typedef]
id: results_in_transport_along
name: results in transport along
def: "Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l " []
xref: RO:0002341
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: related_via_localization_to ! related via localization to

[Typedef]
id: results_in_transport_to_from_or_in
name: results in transport to from or in
xref: RO:0002344
property_value: IAO:0000112 "'mitochondrial transport' results_in_transport_to_from_or_in some  mitochondrion (GO:0005739)" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: related_via_localization_to ! related via localization to

[Typedef]
id: right_of
name: right of
namespace: spatial
def: "Closer to the right side of the organism. Example: The dorsal fin is right of the left pectoral fin, but is left of the right eye. On the type level: X left of Y <=> every instance x of X is right of some instance y of Y, and there exists some organism o such that x part of o and y part of o." [BSPO:cjm]
xref: BSPO:0000111
is_transitive: true

[Typedef]
id: role_of
name: role of
def: "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence" []
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.
xref: RO:0000081
property_value: editor_note "A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists." xsd:string
property_value: IAO:0000112 "this investigator role is a role of this person" xsd:string
property_value: IAO:0000118 "is role of" xsd:string
property_value: IAO:0000118 "role_of" xsd:string
is_a: characteristic_of ! characteristic of
inverse_of: has_role ! has role

[Typedef]
id: seeAlso
name: see also
namespace: spatial
namespace: uberon
xref: http://www.w3.org/2000/01/rdf-schema#seeAlso
is_metadata_tag: true

[Typedef]
id: sends_output_to
name: sends output to
xref: RO:0002486
property_value: editor_note "This is an exploratory relation. The label is taken from the FMA. It needs aligned with the neuron-specific relations such as has postsynaptic terminal in." xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: connected_to ! connected to

[Typedef]
id: sexually_homologous_to
name: sexually_homologous_to
namespace: uberon
is_a: homologous_to ! shares ancestor with

[Typedef]
id: similar_in_magnitude_relative_to
name: obsolete similar_in_magnitude_relative_to
namespace: quality
def: "OBSOLETE. q1 similar_in_magnitude_relative_to q2 if and only if magnitude(q1) =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [PATOC:CJM]
comment: Refer to https://github.com/pato-ontology/pato/issues/454 for obsoletion reason.
domain: PATO:0000001 ! quality
range: PATO:0000001 ! quality
is_obsolete: true
replaced_by: RO:0015009

[Typedef]
id: simultaneous_with
name: simultaneous with
namespace: uberon
def: "x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time." []
comment: t1 simultaneous_with t2 iff:=  t1 before_or_simultaneous_with t2  and not (t1 before t2)
subset: ro-eco
xref: RO:0002082
property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
is_symmetric: true
is_transitive: true
is_a: before_or_simultaneous_with ! before or simultaneous with

[Typedef]
id: site_of
name: site_of
namespace: uberon
def: "c site_of p if c is the bearer of a disposition that is realized by a process that has p as part." []
synonym: "capable_of_has_part" RELATED []

[Typedef]
id: skeleton_of
name: skeleton of
namespace: uberon
def: "inverse of has skeleton" []
subset: RO:0002259
xref: RO:0002576
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
domain: UBERON:0000061 ! anatomical structure
range: UBERON:0000061 ! anatomical structure
is_a: part_of ! part_of

[Typedef]
id: spatially_coextensive_with
name: spatially coextensive with
def: "x spatially_coextensive_with y if and inly if x and y have the same location" []
xref: RO:0002379
property_value: curator_notes "This relation is added for formal completeness. It is unlikely to be used in many practical scenarios" xsd:string
property_value: IAO:0000112 "A lump of clay and a statue" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_a: overlaps ! overlaps

[Typedef]
id: spatially_disjoint_from
name: spatially disjoint from
def: "A is spatially_disjoint_from B if and only if they have no parts in common" []
subset: ro-eco
xref: RO:0002163
property_value: curator_notes "Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy" xsd:string
property_value: editor_note "There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom. " xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552
property_value: RO:0001900 RO:0001901
property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern" xsd:anyURI
is_a: mereotopologically_related_to ! mereotopologically related to
expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" []

[Typedef]
id: starts
name: starts
namespace: uberon
def: "inverse of starts with" []
subset: ro-eco
xref: RO:0002223
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 "Chris Mungall" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 "Allen" xsd:string
is_a: part_of ! part_of
is_a: temporally_related_to ! temporally related to
inverse_of: starts_with ! starts with

[Typedef]
id: starts_axis
name: starts axis
namespace: spatial
comment: A directional axis can be divided by a plane. Following Allen Interval Algebra terminology we say that the side on which the axis initiates starts the axis, with the other side finishing the axis. . If s starts axis x, and x has start point p, then x overlaps p
xref: BSPO:0015007
domain: BSPO:0000054 ! anatomical side
range: BSPO:0000010 ! anatomical axis

[Typedef]
id: starts_with
name: starts with
namespace: uberon
def: "x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." []
subset: ro-eco
xref: RO:0002224
property_value: IAO:0000112 "Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor" xsd:string
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 "Chris Mungall" xsd:string
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "started by" xsd:string
is_transitive: true
is_a: has_part ! has part
is_a: temporally_related_to ! temporally related to

[Typedef]
id: subdivision_of
name: subdivision of
namespace: uberon
comment: placeholder relation. X = 'subdivision of A' and subdivision_of some B means that X is the mereological sum of A and B

[Typedef]
id: superficial_to
name: superficial to
namespace: spatial
namespace: uberon
def: "Near the outer surface of the organism. Thus, skin is superficial to the muscle layer." [BSPO:cjm]
xref: BSPO:0000108
is_transitive: true

[Typedef]
id: supplies
name: supplies
namespace: uberon
def: "Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy." []
xref: RO:0002178
property_value: editor_note "Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between an artery and an anatomical structure" xsd:string
property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20064205
domain: UBERON:0001637 ! artery
is_a: connected_to ! connected to

[Typedef]
id: surface_of
name: surface of
namespace: spatial
comment: placeholder. used for relation between anatomical surface and an anatomical side.
xref: BSPO:0015008
domain: BSPO:0000005 ! anatomical surface

[Typedef]
id: surrounded_by
name: surrounded by
namespace: uberon
def: "x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x" []
xref: RO:0002219
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: RO:0001900 RO:0001901
is_a: adjacent_to ! adjacent to
inverse_of: surrounds ! surrounds

[Typedef]
id: surrounds
name: surrounds
namespace: uberon
def: "inverse of surrounded by" []
subset: RO:0002259
xref: RO:0002221
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: RO:0001900 RO:0001901
is_a: adjacent_to ! adjacent to

[Typedef]
id: synapsed_by
name: synapsed by
namespace: uberon
def: "Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. " []
xref: RO:0002103
property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: RO:0001900 RO:0001901
is_a: receives_input_from ! receives input from
inverse_of: synapsed_to ! synapsed to
expand_expression_to: "BFO_0000051 some (GO_0045211 that part_of some (GO_0045202 that has_part some (GO_0042734 that BFO_0000050 some Y?)))" []

[Typedef]
id: synapsed_to
name: synapsed to
def: " Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.\n        " []
comment: N1 synapsed_to some N2 \nExpands to:\nN1 SubclassOf ( \n   has_part some (\n      ‘pre-synaptic membrane ; GO:0042734’ that part_of some ( \n	‘synapse ; GO:0045202’ that has_part some (\n	   ‘post-synaptic membrane ; GO:0045211’ that part_of some N2))))
xref: RO:0002120
property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172
property_value: RO:0001900 RO:0001901
is_a: sends_output_to ! sends output to
expand_expression_to: "BFO_0000051 some (GO_0042734 that part_of some (GO_0045202 that BFO_0000051 some (GO_0045211 that BFO_0000050 some Y?)))" []

[Typedef]
id: temporally_related_to
name: temporally related to
comment: A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.
subset: ro-eco
xref: RO:0002222
property_value: curator_notes "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends." xsd:string
property_value: http://purl.org/dc/terms/source "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1" xsd:anyURI
property_value: IAO:0000114 IAO:0000125
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000119 https://en.wikipedia.org/wiki/Allen%27s_interval_algebra
domain: BFO:0000003 ! occurrent
range: BFO:0000003 ! occurrent

[Typedef]
id: transformation_of
name: transformation of
namespace: uberon
def: "x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships" []
xref: RO:0002494
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
is_transitive: true
is_a: develops_from ! develops from

[Typedef]
id: transitively_anteriorly_connected_to
name: transitively anteriorly connected to
namespace: uberon
property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI
is_transitive: true

[Typedef]
id: transitively_distally_connected_to
name: transitively distally connected to
namespace: uberon
property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI
is_transitive: true

[Typedef]
id: transitively_proximally_connected_to
name: transitively proximally connected to
namespace: uberon
property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI
is_transitive: true

[Typedef]
id: tributary_of
name: tributary of
namespace: uberon
def: "x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein." []
subset: ro-eco
xref: RO:0002376
property_value: curator_notes "This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (veins, arteries)" xsd:anyURI
property_value: IAO:0000112 "Deschutes River tributary_of Columbia River" xsd:string
property_value: IAO:0000112 "inferior epigastric vein tributary_of external iliac vein" xsd:string
property_value: IAO:0000114 IAO:0000428
property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165
property_value: IAO:0000118 "drains into" xsd:string
property_value: IAO:0000118 "drains to" xsd:string
property_value: IAO:0000118 "tributary channel of" xsd:string
property_value: IAO:0000119 "http://en.wikipedia.org/wiki/Tributary" xsd:string
property_value: IAO:0000119 "http://www.medindia.net/glossary/venous_tributary.htm" xsd:string
property_value: seeAlso http://dbpedia.org/ontology/drainsTo
property_value: seeAlso "http://en.wikipedia.org/wiki/Tributary" xsd:anyURI
is_a: connected_to ! connected to
is_a: in_branching_relationship_with ! in branching relationship with

[Typedef]
id: ventral_to
name: ventral to
namespace: spatial
namespace: uberon
def: "x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly)." [BSPO:cjm]
xref: BSPO:0000102
property_value: seeAlso FBcv:0000049
property_value: seeAlso FBql:00005866
is_transitive: true