has part chebi_ontology false has_part hydrogen acceptor A A molecular entity that can undergo reduction by the gain of hydrogen atom(s). CHEBI:13193 R chebi_ontology A UniProt: ChEBI: R electron donor A molecular entity that can transfer an electron to another molecular entity. CHEBI:15022 Elektronendonator chebi_ontology donneur d'electron electron donor IUPAC: electron donor ChEBI: Elektronendonator IUPAC: donneur d'electron acceptor A A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity. Acceptor Akzeptor CHEBI:13699 CHEBI:15339 CHEBI:2377 KEGG COMPOUND:C00028 accepteur acceptor chebi_ontology Akzeptor ChEBI: KEGG COMPOUND KEGG COMPOUND:C00028 A KEGG COMPOUND: Acceptor KEGG COMPOUND: ChEBI: accepteur UniProt: acceptor hydrogen donor A molecular entity that can undergo oxidation by the loss of hydrogen atom(s). AH2 CHEBI:13233 CHEBI:15018 CHEBI:17499 CHEBI:8785 KEGG COMPOUND:C00030 RH2 Reduced acceptor chebi_ontology ChEBI: RH2 KEGG COMPOUND: Reduced acceptor AH2 UniProt: KEGG COMPOUND KEGG COMPOUND:C00030 AH2 KEGG COMPOUND: electron acceptor A substance to which an electron may be transferred. CHEBI:14207 CHEBI:14716 CHEBI:17654 CHEBI:7835 Elektronenakzeptor KEGG COMPOUND:C02177 Oxidized donor chebi_ontology electron acceptor oxidized donor KEGG COMPOUND KEGG COMPOUND:C02177 IUPAC: electron acceptor ChEBI: Elektronenakzeptor KEGG COMPOUND: Oxidized donor UniProt: oxidized donor donor A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity. CHEBI:14202 CHEBI:17891 CHEBI:4697 Donator Donor KEGG COMPOUND:C01351 chebi_ontology donneur donor ChEBI: Donator KEGG COMPOUND KEGG COMPOUND:C01351 Donor KEGG COMPOUND: ChEBI: donneur UniProt: donor 5-enolpyruvylshikimate-3-phosphate synthase inhibitor CHEBI:20569 chebi_ontology ATP synthase inhibitor A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase. CHEBI:20854 chebi_ontology vitamin C CHEBI:21241 CiteXplore:21885436 Vitamin C chebi_ontology vitamina C vitamine C vitaminum C ChEBI: Vitamin C ChEBI: vitamine C ChEBI: vitamina C ChEBI: vitaminum C PubMed citation CiteXplore:21885436 acaricide A substance used to destroy pests of the subclass Acari (mites and ticks). Akarizid Akarizide CHEBI:22153 Wikipedia:Acaricide acaricides chebi_ontology miticide Akarizid ChEBI: Wikipedia Wikipedia:Acaricide Akarizide ChEBI: ChEBI: acaricides ChEBI: miticide acetohydroxyacid synthase inhibitor CHEBI:22180 chebi_ontology alicyclic antibiotics CHEBI:22309 chebi_ontology aliphatic antibiotics CHEBI:22311 chebi_ontology alkylating agent CHEBI:22333 Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases. chebi_ontology alpha-1-microglobulin-Ig alpha complex chromophores CHEBI:22368 chebi_ontology amino acid derivative antibiotics CHEBI:22476 chebi_ontology antiauxins CHEBI:22581 chebi_ontology antibiotic A substance that is biostatic or biocidal at low concentrations towards bacteria, yeasts, moulds, or other form of life, especially pathogenic or noxious organisms. Although the term was originally restricted to substances produced by microorganisms, its use was later expanded to include derivatives of such substances and it is now commonly used to include entirely synthetic compounds. Antibiotika Antibiotikum CHEBI:22582 CiteXplore:12964249 CiteXplore:22117953 CiteXplore:22439833 CiteXplore:22849268 CiteXplore:22849276 CiteXplore:22958833 antibiotic antibiotics antibiotique chebi_ontology Antibiotika ChEBI: PubMed citation CiteXplore:12964249 PubMed citation CiteXplore:22439833 IUPAC: antibiotique ChEBI: antibiotics PubMed citation CiteXplore:22117953 PubMed citation CiteXplore:22849268 PubMed citation CiteXplore:22958833 IUPAC: antibiotic Antibiotikum ChEBI: PubMed citation CiteXplore:22849276 antifeedant A substance that prevents pests from feeding. CHEBI:22583 antifeedants chebi_ontology ChEBI: antifeedants antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. CHEBI:22586 antioxidants antioxydant antoxidant chebi_ontology ChEBI: antioxidants ChEBI: antoxidant ChEBI: antioxydant antiviral agent A substance that destroys or inhibits replication of viruses. CHEBI:22587 anti-viral agent anti-viral agents antiviral antiviral agents antivirals chebi_ontology ChEBI: antiviral ChEBI: antiviral agents ChEBI: antivirals ChEBI: anti-viral agent ChEBI: anti-viral agents auxin Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow"). CHEBI:22676 Wikipedia:Auxin auxins chebi_ontology Wikipedia Wikipedia:Auxin ChEBI: auxins base A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base). Base Basen CHEBI:22695 base bases chebi_ontology IUPAC: base Basen ChEBI: ChEBI: bases ChEBI: base Base ChEBI: phytogenic insecticide An insecticide compound naturally occurring in plants. CHEBI:22917 botanical insecticide botanical insecticides chebi_ontology phytogenic insecticides ChEBI: botanical insecticides ChEBI: botanical insecticide ChEBI: phytogenic insecticides calcium ionophore CHEBI:22986 calcium ionophores chebi_ontology ChEBI: calcium ionophores carbonic anhydrase inhibitor Any enzyme inhibitor that inhibits the action of carbonic anhydrase, EC 4.2.1.1. Such compounds reduce the secretion of H(+) ions by the proximal kidney tubule. CHEBI:23018 EC 4.2.1.1 inhibitor EC 4.2.1.1 inhibitors Wikipedia:Carbonic_anhydrase_inhibitor anhydrase inhibitor anhydrase inhibitors carbonate anhydrase inhibitor carbonate anhydrase inhibitors carbonate dehydratase inhibitor carbonate dehydratase inhibitors carbonate hydro-lyase (carbon-dioxide-forming) inhibitor carbonate hydro-lyase (carbon-dioxide-forming) inhibitors carbonate hydro-lyase inhibitor carbonate hydro-lyase inhibitors carbonic acid anhydrase inhibitor carbonic acid anhydrase inhibitors carbonic anhydrase A inhibitor carbonic anhydrase A inhibitors carbonic anhydrase inhibitor carbonic anhydrase inhibitors carboxyanhydrase inhibitor carboxyanhydrase inhibitors chebi_ontology ChEBI: carbonate hydro-lyase (carbon-dioxide-forming) inhibitor ChEBI: carboxyanhydrase inhibitors ChEBI: carbonate hydro-lyase (carbon-dioxide-forming) inhibitors ChEBI: anhydrase inhibitor ChEBI: EC 4.2.1.1 inhibitor ChEBI: carbonate hydro-lyase inhibitors ChEBI: carbonate dehydratase inhibitor ChEBI: carbonate anhydrase inhibitors ChEBI: carbonic anhydrase A inhibitor ChEBI: EC 4.2.1.1 inhibitors ChEBI: carbonate dehydratase inhibitors ChEBI: carbonate anhydrase inhibitor ChEBI: carbonic anhydrase inhibitor ChEBI: carboxyanhydrase inhibitor ChEBI: anhydrase inhibitors ChEBI: carbonic acid anhydrase inhibitors Wikipedia Wikipedia:Carbonic_anhydrase_inhibitor ChEBI: carbonic anhydrase inhibitors ChEBI: carbonic anhydrase A inhibitors ChEBI: carbonic acid anhydrase inhibitor ChEBI: carbonate hydro-lyase inhibitor chemosterilant A substance intended to sterilize any organism. CHEBI:23092 Wikipedia:Chemosterilant chebi_ontology chemosterilants Wikipedia Wikipedia:Chemosterilant ChEBI: chemosterilants chitin synthesis inhibitor CHEBI:23100 chebi_ontology chromophore CHEBI:23240 The part (atom or group of atoms) of a molecular entity in which the electronic transition responsible for a given spectral band is approximately localized. chebi_ontology chromophore chromophores IUPAC: chromophore ChEBI: chromophores coenzyme A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons. CHEBI:23354 chebi_ontology coenzyme coenzymes IUPAC: coenzyme ChEBI: coenzymes cofactor An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). CHEBI:23357 Wikipedia:Cofactor_(biochemistry) chebi_ontology cofactor cofactors IUPAC: cofactors IUPAC: cofactor Wikipedia Wikipedia:Cofactor_(biochemistry) compatible osmolytes CHEBI:23366 chebi_ontology cytochrome-b6f complex inhibitor CHEBI:23529 chebi_ontology cytokinin A phytohormone that promote cell division, or cytokinesis, in plant roots and shoots. CHEBI:23530 Wikipedia:Cytokinin chebi_ontology Wikipedia Wikipedia:Cytokinin defoliant A herbicide which when sprayed or dusted on plants causes its leaves to fall off. CHEBI:23582 Defoliationsmittel Entlaubungsmittel chebi_ontology defoliants ChEBI: Entlaubungsmittel ChEBI: defoliants ChEBI: Defoliationsmittel drug Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. CHEBI:23888 chebi_ontology drugs medicine ChEBI: medicine ChEBI: drugs ecdysone antagonists CHEBI:23891 chebi_ontology enzyme inhibitor A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. CHEBI:23924 chebi_ontology enzyme inhibitor enzyme inhibitors inhibidor enzimatico inhibidores enzimaticos inhibiteur enzymatique inhibiteurs enzymatiques ChEBI: inhibiteurs enzymatiques IUPAC: enzyme inhibitor ChEBI: enzyme inhibitors ChEBI: inhibidores enzimaticos ChEBI: inhibiteur enzymatique ChEBI: inhibidor enzimatico ethylene releasers CHEBI:24002 chebi_ontology fat-soluble vitamin CHEBI:24020 chebi_ontology fat-soluble vitamins fettloesliche Vitamine ChEBI: fat-soluble vitamins ChEBI: fettloesliche Vitamine iron(3+) chelator CHEBI:24028 chebi_ontology fungicide A substance used to destroy fungal pests. CHEBI:24127 chebi_ontology fungicides ChEBI: fungicides glutamine synthetase inhibitor CHEBI:24319 chebi_ontology group transfer coenzymes CHEBI:24430 chebi_ontology biological role A role played by the molecular entity or part thereof within a biological context. CHEBI:24432 biological function chebi_ontology ChEBI: biological function herbicide A substance used to destroy plant pests. CHEBI:24527 Herbizid Unkrautbekaempfungsmittel Unkrautvertilgungsmittel Wikipedia:Herbicide Wildkrautbekaempfungsmittel chebi_ontology herbicides ChEBI: Unkrautbekaempfungsmittel ChEBI: Unkrautvertilgungsmittel ChEBI: herbicides ChEBI: Wildkrautbekaempfungsmittel ChEBI: Herbizid Wikipedia Wikipedia:Herbicide hormone CHEBI:24621 Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. chebi_ontology endocrine hormones ChEBI: endocrine ChEBI: hormones insect attractant A chemical that lures insects to a trap, thereby removing them from crops, animals or stored products. CHEBI:24850 CiteXplore:7044287 chebi_ontology insect attractants ChEBI: insect attractants PubMed citation CiteXplore:7044287 insect growth regulator A growth regulator that inhibits the life cycle of an insect. CHEBI:24851 chebi_ontology insect growth regulators ChEBI: insect growth regulators insecticide CHEBI:24852 Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects. Wikipedia:Insecticide chebi_ontology insecticides Wikipedia Wikipedia:Insecticide ChEBI: insecticides intercalator A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages. CHEBI:24853 agente intercalante chebi_ontology intercalating agent intercalating agents intercalating ligands intercalators ChEBI: intercalating agent ChEBI: intercalators ChEBI: agente intercalante ChEBI: intercalating ligands ChEBI: intercalating agents ionophore A compound which can carry specific ions through membranes of cells or organelles. CHEBI:24869 chebi_ontology ionophore ionophores ChEBI: ionophores IUPAC: ionophore iron ionophore CHEBI:24874 chebi_ontology jasmonates CHEBI:24937 chebi_ontology juvenile hormone antagonists CHEBI:24941 chebi_ontology juvenile hormone mimic CHEBI:24942 chebi_ontology luciferin A low-molecular-mass compound present in bioluminescent organisms that emits light when oxidized in presence of enzyme luciferase. CHEBI:25078 chebi_ontology metabolite Any intermediate or product resulting from metabolism. CHEBI:25212 chebi_ontology metabolite metabolites IUPAC: metabolite ChEBI: metabolites mitochondrial respiratory-chain inhibitor CHEBI:25355 chebi_ontology mitochondrial electron transport chain inhibitors mitochondrial electron-transport chain inhibitor mitochondrial respiratory chain inhibitors ChEBI: mitochondrial electron transport chain inhibitors ChEBI: mitochondrial respiratory chain inhibitors ChEBI: mitochondrial electron-transport chain inhibitor mutagen An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution. CHEBI:25435 Wikipedia:Mutagen chebi_ontology mutagene mutagenes mutagenic agent mutageno mutagenos mutagens ChEBI: mutageno ChEBI: mutagenic agent Wikipedia Wikipedia:Mutagen ChEBI: mutagenos ChEBI: mutagenes ChEBI: mutagens ChEBI: mutagene mycotoxin CHEBI:25442 Poisonous substance produced by fungi. chebi_ontology fungal toxins mycotoxins ChEBI: mycotoxins ChEBI: fungal toxins nematicide A substance used to destroy pests of the phylum Nematoda (roundworms). CHEBI:25491 Wikipedia:Nematicide chebi_ontology nematicides nematocide Wikipedia Wikipedia:Nematicide ChEBI: nematicides ChEBI: nematocide neurotransmitter An endogenous compound that is used to transmit information across the synapse between a neuron and another cell. CHEBI:25512 Wikipedia:Neurotransmitter chebi_ontology neurotransmitters ChEBI: neurotransmitters Wikipedia Wikipedia:Neurotransmitter nodulation factor A role played by signal molecules produced by the symbiotic bacteria that trigger nodule formation (typically on the host plant roots). CHEBI:25573 NF chebi_ontology nod factor nodulation factors ChEBI: nodulation factors ChEBI: NF ChEBI: nod factor nucleoside antibiotic CHEBI:25605 chebi_ontology osmolyte A solute used by a cell under water stress to maintain cell volume. CHEBI:25728 chebi_ontology osmolytes ChEBI: osmolytes oxidized luciferins CHEBI:25747 chebi_ontology pesticide synergist A substance that increases the efficacy of a pesticide. CHEBI:25943 chebi_ontology pesticide synergists ChEBI: pesticide synergists pesticide CHEBI:25944 Pestizid Pestizide Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Wikipedia:Pesticide chebi_ontology pesticide pesticides ChEBI: pesticides ChEBI: Pestizid Wikipedia Wikipedia:Pesticide IUPAC: pesticide ChEBI: Pestizide pheromone CHEBI:26013 Substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour. chebi_ontology ectohormone feromone pheromone pheromones IUPAC: ectohormone IUPAC: pheromone ChEBI: pheromones IUPAC: feromone phosphorus containing antibiotics CHEBI:26083 chebi_ontology photosynthetic electron-transport chain inhibitor CHEBI:26087 chebi_ontology photosystem-I inhibitor CHEBI:26088 chebi_ontology photosystem-II inhibitor CHEBI:26089 chebi_ontology phytoalexin A toxin made by a plant that acts against an organism attacking it. CHEBI:26115 chebi_ontology phytoalexins ChEBI: phytoalexins biological pigment An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light. CHEBI:26130 chebi_ontology pigments ChEBI: pigments plant growth regulator A chemical, natural or artificial, that can affect the rate of growth of a plant. CHEBI:26155 chebi_ontology plant growth regulators ChEBI: plant growth regulators plant growth stimulator CHEBI:26157 chebi_ontology plant growth stimulators ChEBI: plant growth stimulators precocenes CHEBI:26220 chebi_ontology prosthetic group A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity. CHEBI:26348 chebi_ontology groupe prosthetique prosthetic group prosthetic groups IUPAC: prosthetic group IUPAC: groupe prosthetique ChEBI: prosthetic groups pyrethroid insecticide CHEBI:26413 chebi_ontology pyrethroid insecticides ChEBI: pyrethroid insecticides secondary metabolite A metabolite that is not directly involved in the normal growth, development or reproduction of an organism. CHEBI:26619 chebi_ontology natural product natural products secondary metabolites ChEBI: natural products ChEBI: secondary metabolites ChEBI: natural product semiochemical A molecular messenger released by an organism that affects the behaviour within or between species. CHEBI:26645 Wikipedia:Semiochemical chebi_ontology semiochemicals Wikipedia Wikipedia:Semiochemical ChEBI: semiochemicals sideramine CHEBI:26671 chebi_ontology siderophore Any of low-molecular-mass iron(III)-chelating compounds produced by microorganisms for the purpose of the transport and sequestration of iron. CHEBI:26672 chebi_ontology ferrioxamine ferrioxamines ironophore siderochrome siderochromes siderophore siderophores ChEBI: siderochrome ChEBI: ferrioxamines IUPAC: siderophore ChEBI: ferrioxamine ChEBI: siderophores ChEBI: ironophore ChEBI: siderochromes synthetic auxin A synthetic compound exhibiting auxin activity. CHEBI:26841 chebi_ontology synthetic auxins ChEBI: synthetic auxins systemic acquired resistance inducing compounds CHEBI:26842 chebi_ontology toxin CHEBI:27026 Poisonous substance produced by a biological organism such as a microbe, animal or plant. Wikipedia:Toxin chebi_ontology toxin toxins Wikipedia Wikipedia:Toxin ChEBI: toxins IUPAC: toxin micronutrient CHEBI:27027 chebi_ontology triaziquone CHEBI:27090 chebi_ontology volatile oil component Any secondary metabolite that is found naturally as a component of a volatile oil. CHEBI:27311 chebi_ontology essential oil component essential oil components ethereal oil component ethereal oil components volatile oil components ChEBI: essential oil component ChEBI: essential oil components ChEBI: volatile oil components ChEBI: ethereal oil components ChEBI: ethereal oil component water-soluble vitamin CHEBI:27314 chebi_ontology wasserloesliche Vitamine water-soluble vitamins ChEBI: water-soluble vitamins ChEBI: wasserloesliche Vitamine xenobiotic organic ethers CHEBI:27334 chebi_ontology detergent A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions. CHEBI:23648 CHEBI:27780 CHEBI:4456 Detergents KEGG COMPOUND:C01689 chebi_ontology detergent KEGG COMPOUND KEGG COMPOUND:C01689 Detergents KEGG COMPOUND: IUPAC: detergent vitamin An organic substance that is distributed in foodstuffs, is distinct from the main organic components of food (protein, carbohydrate and fat) and is needed for the normal nutrition of the organism in question. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines. CHEBI:10004 CHEBI:27305 CHEBI:33229 Vitamin chebi_ontology vitamina vitaminas vitamine vitamines vitamins vitaminum ChEBI: vitamine ChEBI: vitaminum ChEBI: vitaminas ChEBI: Vitamin ChEBI: vitamina ChEBI: vitamines ChEBI: vitamins antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. CHEBI:33231 antitubercular antitubercular agents antitubercular drug antitubercular drugs chebi_ontology tuberculostatic agent ChEBI: antitubercular agents ChEBI: antitubercular drugs ChEBI: antitubercular drug ChEBI: tuberculostatic agent ChEBI: antitubercular application CHEBI:33232 Intended use of the molecular entity or part thereof by humans. chebi_ontology molecular messenger CHEBI:33280 chebi_ontology chemical messenger ChEBI: chemical messenger antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. CHEBI:33281 antimicrobial antimicrobials chebi_ontology microbicide microbicides ChEBI: antimicrobial ChEBI: microbicides ChEBI: microbicide ChEBI: antimicrobials antibacterial agent A substance that kills or slows the growth of bacteria. CHEBI:33282 antibacterial agents antibacterials bactericide bactericides chebi_ontology ChEBI: bactericides ChEBI: antibacterial agents ChEBI: antibacterials ChEBI: bactericide nutrient A nutrient is a chemical element needed by all life forms. CHEBI:33284 chebi_ontology nutrients ChEBI: nutrients agrochemical An agrochemical is a substance that is used in agriculture or horticulture. CHEBI:33286 Wikipedia:Agrochemical agrichemical agrichemicals agricultural chemicals agrochemicals chebi_ontology Wikipedia Wikipedia:Agrochemical ChEBI: agrichemicals ChEBI: agrochemicals ChEBI: agricultural chemicals ChEBI: agrichemical fertilizer A fertilizer is any substance that is added to soil or water to assist the growth of plants. CHEBI:33287 chebi_ontology fertiliser fertilizers ChEBI: fertiliser ChEBI: fertilizers rodenticide A substance used to destroy rodent pests. CHEBI:33288 Wikipedia:Rodenticide chebi_ontology rodenticides ChEBI: rodenticides Wikipedia Wikipedia:Rodenticide avicide A substance used to destroy bird pests (class Aves). CHEBI:33289 Wikipedia:Avicide avicides chebi_ontology Wikipedia Wikipedia:Avicide ChEBI: avicides food Any material that can be ingested by an organism. CHEBI:33290 chebi_ontology fuel An energy-rich substance that can be transformed with release of usable energy. CHEBI:33292 chebi_ontology diagnostic agent A substance administered to aid diagnosis of a disease. CHEBI:33295 chebi_ontology diagnostic aid ChEBI: diagnostic aid reagent A substance used in a chemical reaction to detect, measure, examine, or produce other substances. CHEBI:33893 chebi_ontology reactif reactivo reagent reagents IUPAC: reagent IUPAC: reactif ChEBI: reagents IUPAC: reactivo molluscicide A substance used to destroy pests of the phylum Mollusca. CHEBI:33904 Wikipedia:Molluscicide chebi_ontology molluscicides ChEBI: molluscicides Wikipedia Wikipedia:Molluscicide macronutrient CHEBI:33937 chebi_ontology surfactant A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces. CHEBI:35195 chebi_ontology surface active agent surfactant surfactants IUPAC: surfactant ChEBI: surfactants IUPAC: surface active agent lumiphore A part of a molecular entity (atom or group of atoms) in which electronic excitation associated with a given emission band is approximately localized. CHEBI:35197 chebi_ontology luminophore lumiphore IUPAC: lumiphore IUPAC: luminophore tracer A role played by a foreign substance mixed with or attached to a given substance to enable the distribution or location of the latter to be determined subsequently. CHEBI:35204 chebi_ontology tracer IUPAC: tracer chemical tracer A role played by a chemical compound with properties similar to those of the substance being traced with which it is mixed homogeneously. CHEBI:35205 chebi_ontology chemical tracer IUPAC: chemical tracer isotopic tracer A tracer which only differs in isotopic composition from the substance to be traced. CHEBI:35206 chebi_ontology isotopic tracer IUPAC: isotopic tracer radioactive tracer A tracer containing a radioactive label. CHEBI:35207 chebi_ontology radioactive tracer IUPAC: radioactive tracer physical tracer A physical tracer is one that is attached by physical means to the object being traced. CHEBI:35208 chebi_ontology physical tracer IUPAC: physical tracer label A role played by a part of a molecular entity distinguishable by the observer but not by the system and used to identify a tracer. CHEBI:35209 chebi_ontology label IUPAC: label spin label A role played by a stable paramagnetic group that is attached to a part of a molecular entity whose microscopic environment is of interest and may be revealed by the electron spin resonance (ESR) spectroscopy. CHEBI:35210 chebi_ontology spin label IUPAC: spin label radioactive label CHEBI:35211 chebi_ontology radioactive label IUPAC: radioactive label plant growth retardant CHEBI:26154 CHEBI:26156 CHEBI:35219 chebi_ontology plant growth inhibitor plant growth inhibitors plant growth retardants ChEBI: plant growth inhibitors ChEBI: plant growth inhibitor ChEBI: plant growth retardants primary metabolite A metabolite that is directly involved in the normal growth, development or reproduction of an organism. CHEBI:35220 chebi_ontology primary metabolites ChEBI: primary metabolites antimetabolite A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. CHEBI:35221 Wikipedia:Antimetabolite antimetabolite antimetabolites chebi_ontology IUPAC: antimetabolite Wikipedia Wikipedia:Antimetabolite ChEBI: antimetabolites inhibitor A substance that diminishes the rate of a chemical reaction. CHEBI:35222 chebi_ontology inhibidor inhibiteur inhibitor inhibitors ChEBI: inhibiteur ChEBI: inhibidor ChEBI: inhibitors IUPAC: inhibitor catalyst A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction. CHEBI:35223 Katalysator catalizador catalyseur catalyst chebi_ontology ChEBI: catalizador ChEBI: catalyseur IUPAC: catalyst ChEBI: Katalysator effector A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) enzyme by binding to the enzyme at the regulatory site (which is different from the substrate-binding catalytic site). CHEBI:35224 Wikipedia:Effector_(biology) chebi_ontology effector enzyme modulator IUPAC: effector Wikipedia Wikipedia:Effector_(biology) ChEBI: enzyme modulator buffer Any substance or mixture of substances that, in solution (typically aqueous), resists change in pH upon addition of small amounts of acid or base. CHEBI:35225 buffer compound buffer compounds chebi_ontology ChEBI: buffer compounds ChEBI: buffer compound spin probe A role played by a stable paramagnetic molecular entity used to study the microscopic environment by electron paramagnetic resonance (EPR) spectroscopy without covalent attachment to the molecular entity of interest. CHEBI:35226 chebi_ontology spin probe IUPAC: spin probe fossil fuel A fuel such as coal, oil and natural gas which has formed over many years through the decomposition of deposited vegetation which was under extreme pressure of an overburden of earth. CHEBI:35230 chebi_ontology fossil fuel IUPAC: fossil fuel nuclear fuel CHEBI:35231 Material containing fissile nuclides, which when placed in a reactor, enables a chain reaction to be achieved. chebi_ontology nuclear fuel IUPAC: nuclear fuel radiopharmaceutical Any pharmaceutical compound containing a radioisotope. CHEBI:35232 Wikipedia:Radiopharmaceutical chebi_ontology radiopharmaceuticals Wikipedia Wikipedia:Radiopharmaceutical ChEBI: radiopharmaceuticals central nervous system stimulant Any drug that enhances the activity of the central nervous system. CHEBI:35337 CNS stimulant Wikipedia:Central_nervous_system_stimulants analeptic analeptic agent analeptic drug analeptics central nervous system stimulant central stimulant chebi_ontology Wikipedia Wikipedia:Central_nervous_system_stimulants ChEBI: analeptics CNS stimulant ChEBI: ChEBI: analeptic ChEBI: analeptic drug ChEBI: analeptic agent ChEBI: central stimulant ChEBI: central nervous system stimulant antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. CHEBI:35441 anti-infective agents anti-infective drugs antiinfective agents antiinfective drug chebi_ontology ChEBI: anti-infective drugs ChEBI: antiinfective agents ChEBI: anti-infective agents ChEBI: antiinfective drug antiparasitic agent A substance used to treat or prevent parasitic infections. CHEBI:35442 Wikipedia:Antiparasitic antiparasitic drugs antiparasitics chebi_ontology parasiticides ChEBI: antiparasitics ChEBI: antiparasitic drugs ChEBI: parasiticides Wikipedia Wikipedia:Antiparasitic anthelminthic drug CHEBI:35443 Substance intended to kill parasitic worms (helminths). anthelminthic anthelminthics anthelmintic anthelmintics antihelminth antihelmintico chebi_ontology ChEBI: anthelmintics ChEBI: antihelmintico IUPAC: anthelminthic ChEBI: antihelminth ChEBI: anthelminthics IUPAC: anthelmintic antinematodal drug A substance used in the treatment or control of nematode infestations. CHEBI:35444 antinematodal agent antinematodal drugs antinematodals chebi_ontology ChEBI: antinematodals ChEBI: antinematodal agent ChEBI: antinematodal drugs angiotensin-converting enzyme inhibitor ACE inhibitor CHEBI:35457 chebi_ontology ACE inhibitor ChEBI: antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. CHEBI:35469 antidepressant drugs antidepressants chebi_ontology thymoanaleptics thymoleptic drugs thymoleptics ChEBI: thymoleptic drugs ChEBI: thymoleptics ChEBI: thymoanaleptics ChEBI: antidepressant drugs ChEBI: antidepressants central nervous system drug A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. CHEBI:35470 CNS agent CNS drugs central nervous system agents chebi_ontology CNS agent ChEBI: ChEBI: central nervous system agents CNS drugs ChEBI: psychotropic drug A loosely defined grouping of drugs that have effects on psychological function. CHEBI:35471 Wikipedia:Psychotropic_drug chebi_ontology psychoactive agent psychoactive drugs psychopharmaceuticals psychotropic drugs ChEBI: psychotropic drugs ChEBI: psychoactive agent Wikipedia Wikipedia:Psychotropic_drug ChEBI: psychoactive drugs ChEBI: psychopharmaceuticals anti-inflammatory drug A substance that reduces or suppresses inflammation. CHEBI:35472 anti-inflammatory drugs antiinflammatory agent antiinflammatory drug antiinflammatory drugs chebi_ontology ChEBI: antiinflammatory drugs ChEBI: anti-inflammatory drugs ChEBI: antiinflammatory drug ChEBI: antiinflammatory agent tranquilizing drug A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour. CHEBI:35473 ataractics chebi_ontology tranquilising drug tranquilizing drugs tranquillising agent tranquillizing agents ChEBI: tranquillising agent ChEBI: ataractics ChEBI: tranquilising drug ChEBI: tranquilizing drugs ChEBI: tranquillizing agents anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. CHEBI:35474 anti-anxiety agents anti-anxiety drugs anxiolytic agents anxiolytics chebi_ontology minor tranquilisers minor tranquilizers minor tranquilizing agents ChEBI: minor tranquilisers ChEBI: anti-anxiety agents ChEBI: anxiolytic agents ChEBI: minor tranquilizing agents ChEBI: anti-anxiety drugs ChEBI: minor tranquilizers ChEBI: anxiolytics non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. CHEBI:35475 NSAID NSAIDs Wikipedia:Non-steroidal_anti-inflammatory_drug chebi_ontology non-steroidal anti-inflammatory agent non-steroidal anti-inflammatory drugs ChEBI: non-steroidal anti-inflammatory agent ChEBI: NSAID Wikipedia Wikipedia:Non-steroidal_anti-inflammatory_drug ChEBI: NSAIDs ChEBI: non-steroidal anti-inflammatory drugs antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. CHEBI:35476 Neuroleptikum antipsychotic agents antipsychotic drug antipsychotic drugs antipsychotics antipsychotiques chebi_ontology grosser Tranquilizer major tranquilizers major tranquilizing agents neuroleptic neuroleptic agents neuroleptics neuroleptique neuroleptiques ChEBI: antipsychotics ChEBI: antipsychotic drugs ChEBI: neuroleptic agents ChEBI: Neuroleptikum ChEBI: neuroleptic ChEBI: grosser Tranquilizer ChEBI: antipsychotic agents ChEBI: antipsychotiques ChEBI: neuroleptique ChEBI: neuroleptics ChEBI: major tranquilizing agents ChEBI: major tranquilizers ChEBI: antipsychotic drug ChEBI: neuroleptiques antimanic drug Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders. CHEBI:35477 antimanic agent antimanic drugs antimanics chebi_ontology ChEBI: antimanic agent ChEBI: antimanics ChEBI: antimanic drugs analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. CHEBI:35480 chebi_ontology non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. CHEBI:35481 chebi_ontology opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. CHEBI:35482 chebi_ontology narcotic narcotic analgesic narcotic analgesics narcotics opioid analgesics ChEBI: narcotics ChEBI: narcotic analgesic ChEBI: opioid analgesics ChEBI: narcotic analgesics ChEBI: narcotic aldehyde dehydrogenase inhibitor An enzyme inhibitor that inhibits the action of aldehyde dehydrogenase (EC 1.2.1.3). CHEBI:35487 CoA-independent aldehyde dehydrogenase inhibitor CoA-independent aldehyde dehydrogenase inhibitors EC 1.2.1.3 inhibitor EC 1.2.1.3 inhibitors NAD-aldehyde dehydrogenase inhibitor NAD-aldehyde dehydrogenase inhibitors NAD-dependent 4-hydroxynonenal dehydrogenase inhibitor NAD-dependent 4-hydroxynonenal dehydrogenase inhibitors NAD-dependent aldehyde dehydrogenase inhibitor NAD-dependent aldehyde dehydrogenase inhibitors NAD-linked aldehyde dehydrogenase inhibitor NAD-linked aldehyde dehydrogenase inhibitors Wikipedia:Aldehyde_dehydrogenase aldehyde dehydrogenase (NAD) inhibitor aldehyde dehydrogenase (NAD) inhibitors aldehyde dehydrogenase inhibitors chebi_ontology m-methylbenzaldehyde dehydrogenase inhibitor m-methylbenzaldehyde dehydrogenase inhibitors propionaldehyde dehydrogenase inhibitor propionaldehyde dehydrogenase inhibitors ChEBI: m-methylbenzaldehyde dehydrogenase inhibitors ChEBI: CoA-independent aldehyde dehydrogenase inhibitor ChEBI: NAD-dependent 4-hydroxynonenal dehydrogenase inhibitors ChEBI: propionaldehyde dehydrogenase inhibitors ChEBI: aldehyde dehydrogenase (NAD) inhibitor ChEBI: NAD-dependent 4-hydroxynonenal dehydrogenase inhibitor ChEBI: aldehyde dehydrogenase inhibitors ChEBI: NAD-aldehyde dehydrogenase inhibitor ChEBI: EC 1.2.1.3 inhibitor ChEBI: NAD-dependent aldehyde dehydrogenase inhibitors ChEBI: propionaldehyde dehydrogenase inhibitor ChEBI: NAD-aldehyde dehydrogenase inhibitors Wikipedia Wikipedia:Aldehyde_dehydrogenase ChEBI: aldehyde dehydrogenase (NAD) inhibitors ChEBI: EC 1.2.1.3 inhibitors ChEBI: CoA-independent aldehyde dehydrogenase inhibitors ChEBI: NAD-linked aldehyde dehydrogenase inhibitors ChEBI: m-methylbenzaldehyde dehydrogenase inhibitor ChEBI: NAD-dependent aldehyde dehydrogenase inhibitor ChEBI: NAD-linked aldehyde dehydrogenase inhibitor central nervous system depressant A loosely defined group of drugs that tend to reduce the activity of the central nervous system. CHEBI:35488 CNS depressants central nervous system depressants chebi_ontology ChEBI: central nervous system depressants CNS depressants ChEBI: antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. CHEBI:35493 Wikipedia:Antipyretic anti-pyretic chebi_ontology Wikipedia Wikipedia:Antipyretic ChEBI: anti-pyretic androgen antagonist A compound which inhibits or antagonises the biosynthesis or actions of androgens. CHEBI:35497 antiandrogen chebi_ontology ChEBI: antiandrogen diuretic An agent that promotes the excretion of urine through its effects on kidney function. CHEBI:35498 chebi_ontology diuretics ChEBI: diuretics hallucinogen CHEBI:35499 Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations and other alterations of mood and thinking. chebi_ontology hallucinogenic agents hallucinogenic drugs hallucinogens psychedelic agents psychedelics ChEBI: psychedelic agents ChEBI: hallucinogenic agents ChEBI: psychedelics ChEBI: hallucinogenic drugs ChEBI: hallucinogens beta-adrenergic agonist An agent that selectively binds to and activates beta-adrenergic receptors. CHEBI:35522 beta-adrenergic agonists beta-adrenergic receptor agonist beta-adrenoceptor agonists chebi_ontology ChEBI: beta-adrenergic agonists IUPHAR: beta-adrenoceptor agonists ChEBI: beta-adrenergic receptor agonist bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. CHEBI:35523 bronchodilator bronchodilator agents broncholytic agent chebi_ontology ChEBI: broncholytic agent ChEBI: bronchodilator ChEBI: bronchodilator agents sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. CHEBI:35524 chebi_ontology sympathomimetic sympathomimetics ChEBI: sympathomimetic ChEBI: sympathomimetics hypoglycemic agent A drug which lowers the blood glucose level. CHEBI:35526 antidiabetic antihyperglycemic antihyperglycemic agent antihyperglycemic agents antihyperglycemic drug antihyperglycemic drugs antihyperglycemics chebi_ontology hypoglycemic agents hypoglycemic drug hypoglycemic drugs ChEBI: antidiabetic ChEBI: antihyperglycemic drugs ChEBI: hypoglycemic drug ChEBI: hypoglycemic agents ChEBI: antihyperglycemic ChEBI: antihyperglycemic agents ChEBI: antihyperglycemic drug ChEBI: antihyperglycemic agent ChEBI: hypoglycemic drugs ChEBI: antihyperglycemics beta-adrenergic antagonist An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. CHEBI:35530 beta-adrenergic antagonists beta-adrenergic blocker beta-adrenergic blockers beta-adrenergic receptor blockaders beta-adrenoceptor antagonists chebi_ontology ChEBI: beta-adrenergic blocker ChEBI: beta-adrenergic receptor blockaders ChEBI: beta-adrenergic antagonists ChEBI: beta-adrenergic blockers IUPHAR: beta-adrenoceptor antagonists cyclooxygenase inhibitor A compound or agent that combines with cyclooxygenases and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. CHEBI:35544 COX inhibitor chebi_ontology cyclooxygenase inhibitors ChEBI: cyclooxygenase inhibitors COX inhibitor ChEBI: cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. CHEBI:35554 cardiovascular agent cardiovascular drugs chebi_ontology ChEBI: cardiovascular agent ChEBI: cardiovascular drugs alpha-adrenergic agonist An agent that selectively binds to and activates alpha-adrenergic receptors. CHEBI:35569 alpha-adrenergic agonists alpha-adrenergic receptor agonist alpha-adrenoceptor agonists chebi_ontology IUPHAR: alpha-adrenoceptor agonists ChEBI: alpha-adrenergic receptor agonist ChEBI: alpha-adrenergic agonists protein tyrosine phosphatase inhibitor An enzyme inhibitor which inhibits the activity of the enzyme protein tyrosine phosphatases (PTPs) involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins. CHEBI:35608 chebi_ontology protein tyrosine phosphatase inhibitors ChEBI: protein tyrosine phosphatase inhibitors antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. CHEBI:35610 anticancer agent anticancer agents antineoplastic antineoplastic agents chebi_ontology cytostatic ChEBI: antineoplastic ChEBI: anticancer agents ChEBI: anticancer agent ChEBI: antineoplastic agents ChEBI: cytostatic flavouring agent CHEBI:35617 Substance added to foods and medicine to improve the quality of taste. chebi_ontology flavouring agents food additive ChEBI: food additive ChEBI: flavouring agents vasodilator agent A drug used to cause dilation of the blood vessels. CHEBI:35620 chebi_ontology vasodilator vasodilator agents ChEBI: vasodilator agents ChEBI: vasodilator anticonvulsant A drug used to prevent seizures or reduce their severity. Antiepileptika Antiepileptikum Antikonvulsiva Antikonvulsivum CHEBI:35623 anticonvulsants anticonvulsive agent antiepileptic antiepileptics antiepileptique antiepileptiques chebi_ontology ChEBI: anticonvulsants Antiepileptikum ChEBI: Antikonvulsiva ChEBI: ChEBI: antiepileptique ChEBI: anticonvulsive agent ChEBI: antiepileptiques Antikonvulsivum ChEBI: ChEBI: antiepileptic Antiepileptika ChEBI: ChEBI: antiepileptics beta-lactamase inhibitor CHEBI:35625 beta-lactamase inhibitors chebi_ontology ChEBI: beta-lactamase inhibitors xanthine oxidase inhibitor CHEBI:35634 chebi_ontology xanthine oxidase inhibitors ChEBI: xanthine oxidase inhibitors adrenergic uptake inhibitor ARI Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. CHEBI:35640 NERI NRI adrenergic reuptake inhibitor adrenergic reuptake inhibitors adrenergic uptake inhibitors chebi_ontology norepinephrine reuptake inhibitor norepinephrine reuptake inhibitors ChEBI: NERI ChEBI: norepinephrine reuptake inhibitor ChEBI: adrenergic uptake inhibitors ChEBI: adrenergic reuptake inhibitors ChEBI: norepinephrine reuptake inhibitors ARI ChEBI: ChEBI: adrenergic reuptake inhibitor ChEBI: NRI HIV protease inhibitor An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly. CHEBI:35660 HIV protease inhibitors Wikipedia:Protease_inhibitor_(pharmacology) chebi_ontology Wikipedia Wikipedia:Protease_inhibitor_(pharmacology) ChEBI: HIV protease inhibitors hydroxymethylglutaryl-CoA reductase inhibitor A compound that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. CHEBI:35664 HMG-CoA reductase inhibitor Wikipedia:Statin chebi_ontology hydroxymethylglutaryl-CoA reductase inhibitors statin ChEBI: hydroxymethylglutaryl-CoA reductase inhibitors ChEBI: statin ChEBI: HMG-CoA reductase inhibitor Wikipedia Wikipedia:Statin antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. CHEBI:35674 antihypertensive antihypertensive agents antihypertensive drug antihypertensive drugs chebi_ontology ChEBI: antihypertensive drug ChEBI: antihypertensive agents ChEBI: antihypertensive drugs ChEBI: antihypertensive histamine agonist A drug that binds to and activates histamine receptors. Although they have been suggested for a variety of clinical applications, histamine agonists have so far been more widely used in research than therapeutically. CHEBI:35678 chebi_ontology histamine agonists ChEBI: histamine agonists antilipemic drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). CHEBI:35679 Wikipedia:Hypolipidemic_agent antihyperlipemic antihyperlipemics antihyperlipidemic antihyperlipidemic agent antihyperlipidemic agents antihyperlipidemic drug antihyperlipidemic drugs antihyperlipidemics antilipemic antilipemic drugs antilipemics chebi_ontology hypolipidemic agent hypolipidemic agents ChEBI: antilipemic ChEBI: antihyperlipidemic drug ChEBI: antilipemics ChEBI: antihyperlipidemic ChEBI: antihyperlipemics ChEBI: antihyperlipemic ChEBI: hypolipidemic agent ChEBI: hypolipidemic agents ChEBI: antihyperlipidemics ChEBI: antihyperlipidemic drugs Wikipedia Wikipedia:Hypolipidemic_agent ChEBI: antilipemic drugs ChEBI: antihyperlipidemic agents ChEBI: antihyperlipidemic agent antiplatyhelmintic drug An agent used to treat cestode, trematode, or other flatworm infestations in man or animals. CHEBI:35684 antiplatyhelmintic agent antiplatyhelmintic drugs chebi_ontology ChEBI: antiplatyhelmintic agent ChEBI: antiplatyhelmintic drugs xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. CHEBI:10074 CHEBI:27333 CHEBI:35703 KEGG COMPOUND:C06708 Xenobiotic chebi_ontology xenobiotic xenobiotic compounds xenobiotics IUPAC: xenobiotic IUPAC: xenobiotics ChEBI: xenobiotic compounds KEGG COMPOUND: Xenobiotic KEGG COMPOUND KEGG COMPOUND:C06708 immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. CHEBI:35705 chebi_ontology immunosuppressant immunosuppressive agents inmunosupresor ChEBI: inmunosupresor ChEBI: immunosuppressant ChEBI: immunosuppressive agents sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. CHEBI:35717 chebi_ontology hypnotics hypnotics and sedatives sedative drug sedatives sedatives and hypnotics ChEBI: sedatives and hypnotics ChEBI: sedative drug ChEBI: hypnotics ChEBI: hypnotics and sedatives ChEBI: sedatives antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. Antifungal agents differ from industrial fungicides in that they defend against fungi present in human or animal tissues. CHEBI:35718 antifungal antifungal agents antifungal drug antifungal drugs antifungals chebi_ontology ChEBI: antifungal ChEBI: antifungal drugs ChEBI: antifungal agents ChEBI: antifungals ChEBI: antifungal drug leprostatic drug A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions. CHEBI:35816 chebi_ontology leprostatic leprostatic agent leprostatic drugs ChEBI: leprostatic drugs ChEBI: leprostatic agent ChEBI: leprostatic coccidiostat An agent useful in the treatment or prevention of coccidiosis in man or animals. CHEBI:35818 anticoccidial agent chebi_ontology coccidiostats ChEBI: anticoccidial agent ChEBI: coccidiostats antiprotozoal drug Any antimicrobial drug which is used to treat or prevent protozoal infections. CHEBI:35820 Wikipedia:Antiprotozoal_agent antiprotozoal agent antiprotozoal agents antiprotozoal drugs chebi_ontology ChEBI: antiprotozoal agent ChEBI: antiprotozoal agents Wikipedia Wikipedia:Antiprotozoal_agent ChEBI: antiprotozoal drugs anticholesteremic drug A substance used to lower plasma cholesterol levels. CHEBI:35821 CHEBI:64906 anticholesteremic anticholesteremic agent anticholesteremic drugs antihypercholesterolemic antihypercholesterolemic agent antihypercholesterolemic agents antihypercholesterolemic drug antihypercholesterolemic drugs antihypercholesterolemics chebi_ontology cholesterol inhibitor hypocholesteremic agent ChEBI: antihypercholesterolemic agents ChEBI: antihypercholesterolemic agent ChEBI: antihypercholesterolemic drugs ChEBI: antihypercholesterolemics ChEBI: antihypercholesterolemic ChEBI: anticholesteremic drugs ChEBI: antihypercholesterolemic drug ChEBI: cholesterol inhibitor ChEBI: hypocholesteremic agent ChEBI: anticholesteremic ChEBI: anticholesteremic agent uricosuric drug A gout suppressant that acts directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma. CHEBI:35841 chebi_ontology uricosuric agent uricosuric drugs ChEBI: uricosuric agent ChEBI: uricosuric drugs antirheumatic drug A drug used to treat rheumatoid arthritis. CHEBI:35842 anti-rheumatic drugs antirheumatic agent antirheumatic drugs chebi_ontology ChEBI: anti-rheumatic drugs ChEBI: antirheumatic agent ChEBI: antirheumatic drugs gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout. CHEBI:35845 chebi_ontology gout suppressants ChEBI: gout suppressants renal agent A drug used for its effect on the kidneys' regulation of body fluid composition and volume. CHEBI:35846 chebi_ontology renal agents ChEBI: renal agents lipoxygenase inhibitor A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. CHEBI:35856 chebi_ontology lipooxygenase inhibitor lipoxygenase inhibitors ChEBI: lipoxygenase inhibitors ChEBI: lipooxygenase inhibitor serotonergic agonist 5-HT agonist 5-hydroxytryptamine agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. CHEBI:35941 chebi_ontology serotonergic agonists serotonin agonist serotonin agonists ChEBI: serotonin agonist 5-hydroxytryptamine agonist ChEBI: ChEBI: serotonergic agonists ChEBI: serotonin agonists 5-HT agonist ChEBI: neurotransmitter agent A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. CHEBI:35942 chebi_ontology neurotransmitter agents ChEBI: neurotransmitter agents antimicrobial drug A drug used to treat or prevent microbial infections. CHEBI:36043 antimicrobial drugs chebi_ontology ChEBI: antimicrobial drugs antiviral drug A substance used in the prophylaxis or therapy of virus diseases. CHEBI:36044 anti-viral drug anti-virus drug antiviral drugs chebi_ontology ChEBI: anti-virus drug ChEBI: antiviral drugs ChEBI: anti-viral drug antibacterial drug A drug used to treat or prevent bacterial infections. CHEBI:36047 Wikipedia:Antibacterial antibacterial drugs chebi_ontology Wikipedia Wikipedia:Antibacterial ChEBI: antibacterial drugs antitreponemal drug A drug used in the treatment of infections with bacteria of the genus Treponema. CHEBI:36050 antitreponemal agent antitreponemal drugs chebi_ontology ChEBI: antitreponemal agent ChEBI: antitreponemal drugs antisyphilitic drug A substance that is used in the treatment of syphilis. CHEBI:36051 antisyphilitic agent antisyphilitic agents antisyphilitic drugs antisyphilitics chebi_ontology ChEBI: antisyphilitic drugs ChEBI: antisyphilitics ChEBI: antisyphilitic agent ChEBI: antisyphilitic agents acaricide drug A drug used to treat infestations with arthropods of the subclass Acari (mites and ticks). CHEBI:36053 Wikipedia:Acaricide acaricide drugs chebi_ontology Wikipedia Wikipedia:Acaricide ChEBI: acaricide drugs oxytocic A drug that stimulates contraction of the myometrium. Oxytocics are used to induce labour, obstetric at term, to prevent or control postpartum or postabortion haemorrhage, and to assess foetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (abortifacients). CHEBI:36063 chebi_ontology oxytocic oxytocic agents oxytocic drugs uterine stimulants ChEBI: oxytocic ChEBI: oxytocic drugs ChEBI: oxytocic agents ChEBI: uterine stimulants local anaesthetic Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block. CHEBI:36333 Lokalanaesthetikum anesthesique local chebi_ontology local anaesthetic local anaesthetics local anesthetics ChEBI: Lokalanaesthetikum ChEBI: anesthesique local ChEBI: local anaesthetics ChEBI: local anesthetics IUPAC: local anaesthetic trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. CHEBI:36335 antitrypanosomal agent antitrypanosomal agents antitrypanosomal drug antitrypanosomal drugs chebi_ontology trypanocidal drugs trypanocide trypanosomicidal agents ChEBI: antitrypanosomal agent ChEBI: trypanocide ChEBI: trypanosomicidal agents ChEBI: antitrypanosomal drug ChEBI: antitrypanosomal drugs ChEBI: trypanocidal drugs ChEBI: antitrypanosomal agents anabolic agent A compound which stimulates anabolism and inhibits catabolism. Anabolic agents stimulate the development of muscle mass, strength, and power. CHEBI:36413 chebi_ontology interferon inducer An agent that promotes the production and release of interferons. CHEBI:36710 chebi_ontology interferon inducers ChEBI: interferon inducers protein serine/threonine phosphatase inhibitor CHEBI:37153 chebi_ontology diagnostic imaging agent A substance administered to enhance contrast in images of the inside of the body obtained using X-rays, gamma-rays, sound waves, radio waves (MRI), or radioactive particles in order to diagnose disease. CHEBI:37334 chebi_ontology MRI contrast agent CHEBI:37335 chebi_ontology radioactive imaging agent CHEBI:37336 chebi_ontology ultrasound contrast agent CHEBI:37337 chebi_ontology radioopaque medium A substance having the property of absorbing, and therefore being opaque to, electromagnetic radiation, particularly X-rays. CHEBI:37338 chebi_ontology contrast media radioopaque media radiopaque media radiopaque medium ChEBI: contrast media ChEBI: radiopaque medium ChEBI: radioopaque media ChEBI: radiopaque media RNA polymerase inhibitor An enzyme inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6) CHEBI:37416 RNA polymerase inhibitors Wikipedia:RNA_polymerase chebi_ontology ChEBI: RNA polymerase inhibitors Wikipedia Wikipedia:RNA_polymerase acid Acid An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid). CHEBI:13800 CHEBI:13801 CHEBI:22209 CHEBI:2426 CHEBI:37527 KEGG COMPOUND:C00174 Saeure Saeuren acid acide acido acids an acid chebi_ontology ChEBI: acido ChEBI: Saeuren ChEBI: Saeure UniProt: an acid Acid KEGG COMPOUND: KEGG COMPOUND KEGG COMPOUND:C00174 IUPAC: acid ChEBI: acids IUPAC: acide protease inhibitor A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases). CHEBI:37670 Wikipedia:Protease_inhibitor_(biology) chebi_ontology protease inhibitors Wikipedia Wikipedia:Protease_inhibitor_(biology) ChEBI: protease inhibitors protein kinase inhibitor An agent that inhibits protein kinases. CHEBI:37699 chebi_ontology protein kinase inhibitors ChEBI: protein kinase inhibitors protein kinase C inhibitor CHEBI:37700 chebi_ontology protein kinase C inhibitors ChEBI: protein kinase C inhibitors cholinesterase inhibitor An enzyme inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8). BChE inhibitor BChE inhibitors BtChoEase inhibitor BtChoEase inhibitors CHEBI:37733 EC 3.1.1.8 inhibitor EC 3.1.1.8 inhibitors anticholineesterase inhibitor anticholineesterase inhibitors benzoylcholinesterase inhibitor benzoylcholinesterase inhibitors butyrylcholine esterase inhibitor butyrylcholine esterase inhibitors butyrylcholinesterase inhibitor butyrylcholinesterase inhibitors chebi_ontology choline esterase II (unspecific) inhibitor choline esterase II (unspecific) inhibitors choline esterase inhibitor choline esterase inhibitors non-specific cholinesterase inhibitor non-specific cholinesterase inhibitors propionylcholinesterase inhibitor propionylcholinesterase inhibitors pseudocholinesterase inhibitor pseudocholinesterase inhibitors ChEBI: choline esterase II (unspecific) inhibitor ChEBI: pseudocholinesterase inhibitor ChEBI: choline esterase inhibitors ChEBI: anticholineesterase inhibitors ChEBI: EC 3.1.1.8 inhibitor ChEBI: butyrylcholinesterase inhibitors ChEBI: non-specific cholinesterase inhibitor ChEBI: butyrylcholinesterase inhibitor ChEBI: choline esterase II (unspecific) inhibitors BChE inhibitors ChEBI: ChEBI: propionylcholinesterase inhibitor ChEBI: benzoylcholinesterase inhibitor BtChoEase inhibitor ChEBI: BChE inhibitor ChEBI: ChEBI: benzoylcholinesterase inhibitors ChEBI: non-specific cholinesterase inhibitors BtChoEase inhibitors ChEBI: ChEBI: butyrylcholine esterase inhibitor ChEBI: butyrylcholine esterase inhibitors ChEBI: EC 3.1.1.8 inhibitors ChEBI: pseudocholinesterase inhibitors ChEBI: propionylcholinesterase inhibitors ChEBI: choline esterase inhibitor ChEBI: anticholineesterase inhibitor growth hormone A hormone that specifically regulates growth. CHEBI:37845 Wachstumshormon chebi_ontology growth hormones ChEBI: Wachstumshormon ChEBI: growth hormones plant hormone A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds. CHEBI:26158 CHEBI:37848 Wikipedia:Phytohormone chebi_ontology phytohormone phytohormones plant growth factor plant growth factors plant growth hormone plant growth hormones plant hormones ChEBI: phytohormones ChEBI: plant growth factor Wikipedia Wikipedia:Phytohormone ChEBI: plant growth factors ChEBI: plant hormones ChEBI: plant growth hormone ChEBI: plant growth hormones ChEBI: phytohormone adrenergic agonist An agent that selectively binds to and activates adrenergic receptors. CHEBI:37886 adrenergic agonists adrenergic receptor agonist adrenoceptor agonists adrenomimetic adrenomimetics chebi_ontology ChEBI: adrenergic agonists IUPHAR: adrenoceptor agonists ChEBI: adrenomimetic ChEBI: adrenergic receptor agonist ChEBI: adrenomimetics adrenergic antagonist An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. CHEBI:37887 adrenergic antagonists adrenergic blockaders adrenergic blocker adrenergic blockers adrenergic receptor blockaders adrenoceptor antagonists chebi_ontology ChEBI: adrenergic blocker ChEBI: adrenergic blockers ChEBI: adrenergic antagonists ChEBI: adrenergic blockaders ChEBI: adrenergic receptor blockaders IUPHAR: adrenoceptor antagonists alpha-adrenergic antagonist An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. CHEBI:37890 alpha-adrenergic antagonists alpha-adrenergic blocker alpha-adrenergic blockers alpha-adrenergic receptor blockaders alpha-adrenoceptor antagonists chebi_ontology ChEBI: alpha-adrenergic receptor blockaders ChEBI: alpha-adrenergic blocker ChEBI: alpha-adrenergic blockers ChEBI: alpha-adrenergic antagonists IUPHAR: alpha-adrenoceptor antagonists phenothiazine antipsychotic drug CHEBI:37930 chebi_ontology phenothiazine antipsychotic drugs phenothiazine antipsychotics phenothiazine neuroleptics ChEBI: phenothiazine neuroleptics ChEBI: phenothiazine antipsychotic drugs ChEBI: phenothiazine antipsychotics H1-receptor antagonist CHEBI:37955 CiteXplore:22035879 H1 antihistaminics H1 receptor antagonists H1 receptor blockaders H1-receptor antagonists H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. H1-receptor blocker H1-receptor blockers chebi_ontology classical antihistamines classical antihistaminics ChEBI: classical antihistamines ChEBI: H1-receptor blocker ChEBI: H1 receptor blockaders ChEBI: H1 antihistaminics H1 receptor antagonists IUPHAR: ChEBI: classical antihistaminics ChEBI: H1-receptor antagonists ChEBI: H1-receptor blockers PubMed citation CiteXplore:22035879 histamine antagonist CHEBI:37956 CiteXplore:22035879 Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Wikipedia:Antihistamines antihistamine antihistamines antihistaminico antihistaminics chebi_ontology histamine receptor blocker histamine receptor blockers ChEBI: antihistaminics ChEBI: histamine receptor blockers ChEBI: histamine receptor blocker ChEBI: antihistaminico Wikipedia Wikipedia:Antihistamines ChEBI: antihistamines PubMed citation CiteXplore:22035879 ChEBI: antihistamine histaminergic drug CHEBI:37957 Drugs used for their actions on histaminergic systems. chebi_ontology histamine agents histamine drugs histaminergic agent histaminergic agents histaminergic drugs ChEBI: histaminergic agent ChEBI: histamine agents ChEBI: histaminergic agents ChEBI: histaminergic drugs ChEBI: histamine drugs dye CHEBI:37958 Farbstoff Farbstoffe chebi_ontology colorante colorantes dyes teinture teintures ChEBI: colorante ChEBI: teintures ChEBI: Farbstoffe ChEBI: teinture ChEBI: dyes ChEBI: colorantes ChEBI: Farbstoff H2-receptor antagonist CHEBI:37961 H2 receptor antagonists H2 receptor blockaders H2-receptor antagonists are the drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of endogenous histamine. H2-receptor blocker H2-receptor blockers chebi_ontology histamine H2 receptor antagonist histamine H2 receptor antagonists ChEBI: histamine H2 receptor antagonist ChEBI: H2-receptor blocker ChEBI: H2 receptor blockaders ChEBI: histamine H2 receptor antagonists ChEBI: H2-receptor blockers H2 receptor antagonists IUPHAR: adrenergic agent Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. CHEBI:37962 adrenergic agents adrenergic drug adrenergic drugs adrenergic neuron agents adrenergics chebi_ontology ChEBI: adrenergic agents ChEBI: adrenergic neuron agents ChEBI: adrenergic drug ChEBI: adrenergics ChEBI: adrenergic drugs triazine insecticide CHEBI:38060 chebi_ontology antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. CHEBI:38068 antimalarials chebi_ontology ChEBI: antimalarials anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. CHEBI:38070 antiarrhythmic agent chebi_ontology ChEBI: antiarrhythmic agent cardiotonic drug A drug that has a strengthening effect on the heart or that can increase cardiac output. CHEBI:38147 cardiotonic drugs chebi_ontology ChEBI: cardiotonic drugs phytosiderophore Any of low-molecular-mass iron(III)-chelating compounds produced by plants for the purpose of the transport and sequestration of iron. CHEBI:26122 CHEBI:38117 CHEBI:38155 Phytosiderophor chebi_ontology phytosiderophores ChEBI: phytosiderophores ChEBI: Phytosiderophor iron chelator CHEBI:38157 chebi_ontology iron chelating agents iron chelators ChEBI: iron chelators ChEBI: iron chelating agents chelator A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate. CHEBI:23090 CHEBI:3585 CHEBI:38161 CHEBI:6789 Chelating agent KEGG COMPOUND:C00917 KEGG COMPOUND:C02169 Metal chelator chebi_ontology chelating agents chelators complexon ChEBI: chelating agents KEGG COMPOUND KEGG COMPOUND:C00917 ChEBI: chelators Chelating agent KEGG COMPOUND: KEGG COMPOUND KEGG COMPOUND:C02169 ChEBI: complexon KEGG COMPOUND: Metal chelator iron(2+) chelator CHEBI:38162 chebi_ontology calcium channel blocker CHEBI:38215 One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. calcium channel blockers chebi_ontology ChEBI: calcium channel blockers phytotoxin Any toxin produced by a plant. CHEBI:38231 chebi_ontology phytotoxins ChEBI: phytotoxins DNA polymerase inhibitor CHEBI:38234 DNA polymerase inhibitors chebi_ontology ChEBI: DNA polymerase inhibitors HPPD inhibitor 4-hydroxyphenylpyruvate dioxygenase inhibitor 4-hydroxyphenylpyruvate dioxygenase inhibitors CHEBI:38317 CHEBI:50380 EC 1.13.11.27 inhibitor EC 1.13.11.27 inhibitors HPPD inhibitors Inhibitor of 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27). chebi_ontology ChEBI: HPPD inhibitors ChEBI: EC 1.13.11.27 inhibitors 4-hydroxyphenylpyruvate dioxygenase inhibitors ChEBI: ChEBI: EC 1.13.11.27 inhibitor 4-hydroxyphenylpyruvate dioxygenase inhibitor ChEBI: cholinergic drug Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. CHEBI:38323 chebi_ontology cholinergic agent cholinergic drugs cholinomimetic ChEBI: cholinergic agent ChEBI: cholinomimetic ChEBI: cholinergic drugs cholinergic agonist Any drug that binds to and activates cholinergic receptors. CHEBI:38324 acetylcholine agonist acetylcholine agonists acetylcholine receptor agonist chebi_ontology cholinergic agonists cholinomimetic cholinomimetics ChEBI: cholinergic agonists ChEBI: acetylcholine agonists ChEBI: cholinomimetic ChEBI: acetylcholine agonist ChEBI: cholinomimetics IUPHAR: acetylcholine receptor agonist muscarinic agonist Any drug that binds to and activates a muscarinic cholinergic receptor. CHEBI:38325 chebi_ontology muscarinic acetylcholine receptor agonist muscarinic agonists muscarinic cholinergic agonist muscarinic cholinergic agonists ChEBI: muscarinic acetylcholine receptor agonist ChEBI: muscarinic cholinergic agonists ChEBI: muscarinic agonists ChEBI: muscarinic cholinergic agonist ecdysone agonist CHEBI:38456 chebi_ontology ecdysone agonists ecdysone mimetic ChEBI: ecdysone mimetic ChEBI: ecdysone agonists carbamate insecticide CHEBI:38461 Derivatives of carbamic acid with insecticidal properties of general formula ROC(=O)NR(1)R(2), where ROH is an alcohol, oxime, or phenol and R(1) is hydrogen or methyl. Like organophosphate insecticides, they are cholinesterase inhibitors, but carbamate insecticides differ in action from the organophosphates in that the inhibitory effect on cholinesterase is generally brief. carbamate insecticides chebi_ontology ChEBI: carbamate insecticides acetylcholinesterase inhibitor AChEI An enzyme inhibitor that inhibits the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. CHEBI:38462 Wikipedia:Acetylcholinesterase_inhibitor acetylcholine esterase inhibitor acetylcholinesterase inhibitors chebi_ontology ChEBI: acetylcholinesterase inhibitors AChEI ChEBI: Wikipedia Wikipedia:Acetylcholinesterase_inhibitor ChEBI: acetylcholine esterase inhibitor electron-transport chain inhibitor CHEBI:38496 chebi_ontology respiratory-chain inhibitor CHEBI:38497 chebi_ontology mitochondrial NADH:ubiquinone reductase inhibitor CHEBI:38498 chebi_ontology mitochondrial NADH dehydrogenase inhibitor mitochondrial complex I inhibitor mitochondrial complex I inhibitors ChEBI: mitochondrial complex I inhibitors ChEBI: mitochondrial complex I inhibitor ChEBI: mitochondrial NADH dehydrogenase inhibitor mitochondrial cytochrome-bc1 complex inhibitor CHEBI:38499 chebi_ontology mitochondrial complex III inhibitor mitochondrial complex III inhibitors ChEBI: mitochondrial complex III inhibitors ChEBI: mitochondrial complex III inhibitor mitochondrial cytochrome-c oxidase inhibitor CHEBI:38500 chebi_ontology mitochondrial complex IV inhibitor mitochondrial complex IV inhibitors mitochondrial cytochrome-c oxidase inhibitors ChEBI: mitochondrial complex IV inhibitor ChEBI: mitochondrial complex IV inhibitors ChEBI: mitochondrial cytochrome-c oxidase inhibitors cytochrome-c oxidase inhibitor CHEBI:38501 chebi_ontology cytochrome-bc1 complex inhibitor CHEBI:38502 chebi_ontology NADH:ubiquinone reductase inhibitor A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (EC 1.6.5.3) CHEBI:38503 Coenzyme Q reductase DPNH-coenzyme Q reductase inhibitor DPNH-ubiquinone reductase inhibitor NADH-Q6 oxidoreductase inhibitor NADH-coenzyme Q oxidoreductase inhibitors NADH2 dehydrogenase (ubiquinone) inhibitor NADH:ubiquinone oxidoreductase complex inhibitor NADH:ubiquinone oxidoreductase inhibitor NADH:ubiquinone reductase (H+-translocating) inhibitor chebi_ontology complex 1 dehydrogenase inhibitor complex I (NADH:Q1 oxidoreductase) inhibitors complex I (electron transport chain) inhibitors complex I (mitochondrial electron transport) inhibitors dihydronicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor mitochondrial electron transport complex 1 inhibitor reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor type 1 dehydrogenase inhibitor ubiquinone reductase inhibitor ChEBI: NADH:ubiquinone oxidoreductase inhibitor ChEBI: NADH:ubiquinone oxidoreductase complex inhibitor ChEBI: Coenzyme Q reductase ChEBI: NADH:ubiquinone reductase (H+-translocating) inhibitor ChEBI: complex 1 dehydrogenase inhibitor ChEBI: type 1 dehydrogenase inhibitor ChEBI: DPNH-ubiquinone reductase inhibitor ChEBI: ubiquinone reductase inhibitor ChEBI: NADH-coenzyme Q oxidoreductase inhibitors ChEBI: complex I (NADH:Q1 oxidoreductase) inhibitors ChEBI: DPNH-coenzyme Q reductase inhibitor ChEBI: mitochondrial electron transport complex 1 inhibitor ChEBI: NADH2 dehydrogenase (ubiquinone) inhibitor ChEBI: complex I (electron transport chain) inhibitors ChEBI: NADH-Q6 oxidoreductase inhibitor ChEBI: reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor ChEBI: dihydronicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor ChEBI: complex I (mitochondrial electron transport) inhibitors triazole insecticide CHEBI:38577 chebi_ontology monoamine oxidase inhibitor CHEBI:38623 One of a chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. chebi_ontology monoamine oxidase inhibitors ChEBI: monoamine oxidase inhibitors membrane transport modulator Any agent that affects the transport of molecular entities across a biological membrane. CHEBI:38632 chebi_ontology membrane transport modulators ChEBI: membrane transport modulators sodium channel blocker An agent that inhibits sodium influx through cell membranes. CHEBI:38633 Na channel blocker chebi_ontology sodium channel blockers ChEBI: sodium channel blockers ChEBI: Na channel blocker voltage-gated sodium channel blocker CHEBI:38634 chebi_ontology tyrosine kinase inhibitor Any protein kinase inhibitor that interferes with the action of tyrosine kinase. CHEBI:38637 TKI inhibitor TKI inhibitors Wikipedia:Tyrosine-kinase_inhibitor chebi_ontology protein tyrosine kinase inhibitor protein tyrosine kinase inhibitors tyrosine kinase inhibitors tyrphostin tyrphostins ChEBI: protein tyrosine kinase inhibitor ChEBI: tyrosine kinase inhibitors Wikipedia Wikipedia:Tyrosine-kinase_inhibitor ChEBI: tyrphostin ChEBI: TKI inhibitor ChEBI: tyrphostins ChEBI: TKI inhibitors ChEBI: protein tyrosine kinase inhibitors pediculicide CHEBI:38706 Substance used to treat lice (genus Pediculus) infestation. chebi_ontology pediculicides ChEBI: pediculicides calcium channel agonist Agents that increase calcium influx into calcium channels of excitable tissues. CHEBI:38807 calcium channel activator calcium channel activators calcium channel agonists chebi_ontology ChEBI: calcium channel activator ChEBI: calcium channel agonists ChEBI: calcium channel activators calcium channel modulator A membrane transport modulator that is able to regulate intracellular calcium levels. CHEBI:38808 calcium channel modulators chebi_ontology ChEBI: calcium channel modulators ryanodine receptor modulator CHEBI:38809 RyR modulator chebi_ontology ryanodine receptor modulators ryanodine-sensitive calcium channel modulator ryanodine-sensitive calcium-release channel modulator ChEBI: ryanodine-sensitive calcium channel modulator ChEBI: RyR modulator ChEBI: ryanodine-sensitive calcium-release channel modulator ChEBI: ryanodine receptor modulators nonionic surfactant A surfactant with an uncharged hydrophilic headgroup. CHEBI:38828 chebi_ontology non-ionic surfactant nonionic surfactants ChEBI: nonionic surfactants ChEBI: non-ionic surfactant blood substitute A substance that can carry oxygen to and carbon dioxide away from the tissues when introduced into the blood stream. Blood substitutes are used to replace hemoglobin in severe hemorrhage and also to perfuse isolated organs. CHEBI:38849 artificial blood blood substitutes chebi_ontology oxygen carrier ChEBI: oxygen carrier ChEBI: artificial blood ChEBI: blood substitutes anaesthetic Anaesthetika Anaesthetikum CHEBI:38867 Substance which produces loss of feeling or sensation. anaesthetic anaesthetics anesthetic agent anesthetic drug anesthetics chebi_ontology ChEBI: anesthetic drug ChEBI: anaesthetics ChEBI: anesthetic agent Anaesthetikum ChEBI: ChEBI: anesthetics IUPAC: anaesthetic Anaesthetika ChEBI: general anaesthetic Allgemeinanaesthetika Allgemeinanaesthetikum CHEBI:38869 Substance that produces loss of consciousness. chebi_ontology general anaesthetic general anaesthetics general anesthetics ChEBI: general anesthetics Allgemeinanaesthetika ChEBI: ChEBI: general anaesthetics Allgemeinanaesthetikum ChEBI: IUPAC: general anaesthetic inhalation anaesthetic CHEBI:38870 Inhalationsanaesthetika Inhalationsanaesthetikum Inhalationsnarkotika Inhalationsnarkotikum anesthetic gases chebi_ontology inhalation anesthetics ChEBI: Inhalationsanaesthetikum ChEBI: anesthetic gases ChEBI: inhalation anesthetics ChEBI: Inhalationsnarkotikum ChEBI: Inhalationsanaesthetika ChEBI: Inhalationsnarkotika intravenous anaesthetic CHEBI:38877 chebi_ontology i.v.-Anaesthetika i.v.-Anaesthetikum intravenous anesthetics ChEBI: i.v.-Anaesthetika ChEBI: intravenous anesthetics ChEBI: i.v.-Anaesthetikum schistosomicide drug CHEBI:38941 Drugs that used to treat infestations by flukes (trematodes) of the genus Schistosoma. antischistosoma antischistosomal drug chebi_ontology schistosomicide drugs schistosomicides ChEBI: antischistosomal drug ChEBI: schistosomicide drugs ChEBI: antischistosoma ChEBI: schistosomicides ectoparasiticide CHEBI:38956 chebi_ontology ectoparasiticides ChEBI: ectoparasiticides GABA-gated chloride channel antagonist CHEBI:38999 GABA-gated chloride channel antagonists chebi_ontology ChEBI: GABA-gated chloride channel antagonists sodium channel modulator CHEBI:39000 chebi_ontology sodium channel modulators ChEBI: sodium channel modulators Good's buffer substance Any member of a collection of zwitterionic buffer substances selected or devised for suitability in experimental biological systems according to a number of predetermined criteria. Named after Dr. Norman Good. CHEBI:39011 Good buffer substance Good's buffer Good's buffers Wikipedia:Good's_buffers chebi_ontology ChEBI: Good buffer substance Wikipedia Wikipedia:Good's_buffers ChEBI: Good's buffers ChEBI: Good's buffer pyrethroid ester insecticide CHEBI:39116 chebi_ontology pyrethroid ester insecticides ChEBI: pyrethroid ester insecticides Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). Bronsted acid Bronsted-Saeure CHEBI:39141 acide de Bronsted chebi_ontology donneur d'hydron hydron donor IUPAC: hydron donor IUPAC: acide de Bronsted Bronsted-Saeure ChEBI: IUPAC: donneur d'hydron Bronsted acid IUPAC: Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). Bronsted base Bronsted-Base CHEBI:39142 accepteur d'hydron base de Bronsted chebi_ontology hydron acceptor Bronsted base IUPAC: IUPAC: base de Bronsted IUPAC: hydron acceptor Bronsted-Base ChEBI: IUPAC: accepteur d'hydron Lewis acid A molecular entity that is an electron-pair acceptor and therefore able to form a covalent bond with an electron-pair donor (Lewis base), thereby producing a Lewis adduct. CHEBI:39143 Lewis acid Lewis-Saeure accepteur d'une paire d'electrons acide de Lewis chebi_ontology electron acceptor electron-pair acceptor IUPAC: Lewis acid IUPAC: accepteur d'une paire d'electrons IUPAC: electron-pair acceptor ChEBI: electron acceptor ChEBI: Lewis-Saeure IUPAC: acide de Lewis Lewis base A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct. CHEBI:39144 Lewis base Lewis-Base base de Lewis chebi_ontology donneur d'une paire d'electrons electron donor IUPAC: Lewis base ChEBI: electron donor ChEBI: donneur d'une paire d'electrons IUPAC: base de Lewis ChEBI: Lewis-Base antibiotic insecticide CHEBI:39208 chebi_ontology antibiotic pesticide CHEBI:39215 chebi_ontology antibiotic acaricide CHEBI:39216 chebi_ontology antibiotic nematicide CHEBI:39217 chebi_ontology pyrethroid ester acaricide CHEBI:39259 chebi_ontology fumigant A volatile or volatilizable chemical compound utilized for control of pests in buildings, soil, grain, as well as during processing of goods to be imported or exported to prevent transfer of exotic organisms. CHEBI:39276 Wikipedia:Fumigation chebi_ontology fumigant pesticide fumigants Wikipedia Wikipedia:Fumigation ChEBI: fumigant pesticide ChEBI: fumigants fumigant insecticide CHEBI:39277 chebi_ontology sulfite ester acaricide CHEBI:39301 chebi_ontology mite growth regulator CHEBI:39316 chebi_ontology growth regulator Any chemical substance that inhibits the life-cycle of an organism. CHEBI:39317 chebi_ontology growth regulators ChEBI: growth regulators tetrazine acaricide CHEBI:39318 chebi_ontology pyrethroid ether insecticide CHEBI:39351 chebi_ontology pyrethroid ether insecticides ChEBI: pyrethroid ether insecticides pyrethroid ether acaricide CHEBI:39369 chebi_ontology pyrethroid ether acaricides ChEBI: pyrethroid ether acaricides homopteran inhibitor of chitin biosynthesis CHEBI:39378 chebi_ontology lepidopteran inhibitor of chitin biosynthesis CHEBI:39379 chebi_ontology bridged diphenyl acaricide CHEBI:39412 bridged diphenyl acaricides chebi_ontology ChEBI: bridged diphenyl acaricides dinitrophenol insecticide CHEBI:39415 chebi_ontology dinitrophenol insecticides ChEBI: dinitrophenol insecticides fluorescent probe A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy. CHEBI:39442 chebi_ontology antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. CHEBI:39456 anti-glaucoma agent anti-glaucoma agents anti-glaucoma drug anti-glaucoma drugs antiglaucoma agent antiglaucoma drugs chebi_ontology ChEBI: antiglaucoma agent ChEBI: antiglaucoma drugs ChEBI: anti-glaucoma agents ChEBI: anti-glaucoma drugs ChEBI: anti-glaucoma agent ChEBI: anti-glaucoma drug solvent A liquid that can dissolve other substances (solutes) without any change in their chemical composition. CHEBI:46787 Loesungsmittel Wikipedia:Solvent chebi_ontology solvant solvents Wikipedia Wikipedia:Solvent ChEBI: solvents ChEBI: Loesungsmittel ChEBI: solvant indicator Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc. CHEBI:47867 Indikator chebi_ontology ChEBI: Indikator photosensitizing agent A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells. CHEBI:47868 chebi_ontology photosensitising agent ChEBI: photosensitising agent nicotinic agonist Any drug that binds to and activates a nicotinic cholinergic receptor. CHEBI:47958 chebi_ontology muscarinic agonists ChEBI: muscarinic agonists protein synthesis inhibitor A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein. CHEBI:48001 chebi_ontology protein synthesis antagonist protein synthesis antagonists protein synthesis inhibitors ChEBI: protein synthesis inhibitors ChEBI: protein synthesis antagonists ChEBI: protein synthesis antagonist antiseptic drug A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body). CHEBI:48218 Wikipedia:Antiseptic antiseptic antiseptic agent antiseptic agents antiseptics chebi_ontology local antiinfective agents local microbicides topical antiinfective agents topical microbicides ChEBI: antiseptic agents Wikipedia Wikipedia:Antiseptic ChEBI: local microbicides ChEBI: local antiinfective agents ChEBI: antiseptic ChEBI: antiseptics ChEBI: topical antiinfective agents ChEBI: antiseptic agent ChEBI: topical microbicides disinfectant A substance applied to non-living objects to destroy harmful microorganisms or to inhibit their activity. CHEBI:48219 Desinfektionsmittel chebi_ontology desinfectant disinfectants disinfecting agent ChEBI: disinfecting agent ChEBI: disinfectants ChEBI: Desinfektionsmittel ChEBI: desinfectant serotonergic drug CHEBI:48278 chebi_ontology serotonergic agents serotonergic drugs serotonin drugs ChEBI: serotonergic agents ChEBI: serotonergic drugs ChEBI: serotonin drugs serotonergic antagonist 5-HT antagonists 5-hydroxytryptamine antagonists CHEBI:48279 Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. antiserotonergic agents chebi_ontology serotonin antagonists serotonin blockaders 5-HT antagonists ChEBI: ChEBI: serotonin blockaders 5-hydroxytryptamine antagonists ChEBI: ChEBI: serotonin antagonists ChEBI: antiserotonergic agents fragrance A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell. CHEBI:48318 Parfuem aroma arome chebi_ontology essence parfum perfume scent ChEBI: essence ChEBI: arome ChEBI: Parfuem ChEBI: scent ChEBI: aroma ChEBI: perfume ChEBI: parfum serine proteinase inhibitor An exogenous or endogenous compound which inhibits serine endopeptidases. CHEBI:48353 chebi_ontology serine proteinase inhibitors ChEBI: serine proteinase inhibitors polar solvent A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds. CHEBI:48354 chebi_ontology polar solvent polar solvents ChEBI: polar solvents IUPAC: polar solvent non-polar solvent CHEBI:48355 chebi_ontology protic solvent A polar solvent that is capable of acting as a hydron (proton) donor. CHEBI:48356 chebi_ontology protogenic solvent IUPAC: protogenic solvent aprotic solvent CHEBI:48357 chebi_ontology polar aprotic solvent CHEBI:48358 chebi_ontology protophilic solvent CHEBI:48359 chebi_ontology amphiprotic solvent CHEBI:48360 chebi_ontology catechol O-methyltransferase inhibitor Any inhibitor of catechol O-methyltransferase, EC 2.1.1.6. CHEBI:48406 COMT inhibitor COMT inhibitors EC 2.1.1.6 inhibitor EC 2.1.1.6 inhibitors S-adenosyl-L-methionine:catechol O-methyltransferase inhibitor S-adenosyl-L-methionine:catechol O-methyltransferase inhibitors catechol O-methyltransferase inhibitors chebi_ontology ChEBI: S-adenosyl-L-methionine:catechol O-methyltransferase inhibitors ChEBI: catechol O-methyltransferase inhibitors COMT inhibitors ChEBI: COMT inhibitor ChEBI: ChEBI: S-adenosyl-L-methionine:catechol O-methyltransferase inhibitor ChEBI: EC 2.1.1.6 inhibitors ChEBI: EC 2.1.1.6 inhibitor antiparkinson drug A drug used in the treatment of Parkinson's disease. CHEBI:48407 Wikipedia:Antiparkinson antiparkinson agent chebi_ontology Wikipedia Wikipedia:Antiparkinson ChEBI: antiparkinson agent angiogenesis inhibitor An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. CHEBI:48422 Wikipedia:Angiogenesis_inhibitor angiogenesis antagonist angiostatic agents chebi_ontology ChEBI: angiogenesis antagonist Wikipedia Wikipedia:Angiogenesis_inhibitor ChEBI: angiostatic agents topical anaesthetic A local anesthetic that is used to numb the surface of a body part. CHEBI:48425 chebi_ontology topical anaesthetics topical anesthetic ChEBI: topical anaesthetics ChEBI: topical anesthetic calcimimetic A drug that it mimics the action of calcium on tissues. CHEBI:48525 calcimimetics chebi_ontology ChEBI: calcimimetics alpha-adrenergic drug Any drug that acts on an alpha-adrenergic receptor. CHEBI:48539 alpha-adrenergic drugs chebi_ontology ChEBI: alpha-adrenergic drugs beta-adrenergic drug Any of the drugs that act on beta-adrenergic receptors. CHEBI:48540 beta-adrenergic drugs chebi_ontology ChEBI: beta-adrenergic drugs aldose reductase inhibitor An enzyme inhibitor that inhibits the action of aldose reductase (aldehyde reductase, EC 1.1.1.21). CHEBI:48550 EC 1.1.1.21 inhibitor EC 1.1.1.21 inhibitors aldehyde reductase inhibitor aldehyde reductase inhibitors aldose reductase inhibitors chebi_ontology ChEBI: EC 1.1.1.21 inhibitors ChEBI: EC 1.1.1.21 inhibitor ChEBI: aldehyde reductase inhibitor ChEBI: aldose reductase inhibitors ChEBI: aldehyde reductase inhibitors dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. CHEBI:48560 chebi_ontology dopamine agent dopamine agents dopamine drug dopamine drugs dopaminergic agents ChEBI: dopamine drugs ChEBI: dopamine agent ChEBI: dopamine drug ChEBI: dopamine agents ChEBI: dopaminergic agents dopaminergic antagonist A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. CHEBI:48561 chebi_ontology dopamine antagonist dopamine blocker dopamine receptor antagonist dopaminergic antagonists ChEBI: dopaminergic antagonists ChEBI: dopamine blocker ChEBI: dopamine receptor antagonist ChEBI: dopamine antagonist radical scavenger A role played by a substance that can react readily with, and thereby eliminate, radicals. CHEBI:48578 chebi_ontology free radical scavengers free-radical scavenger ChEBI: free-radical scavenger ChEBI: free radical scavengers gamma-secretase modulator A modulator of gamma secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave. CHEBI:48668 Gamma-secretase modulator Gamma-secretase modulators Wikipedia:Gamma_secretase chebi_ontology gamma secretase modulator gamma secretase modulators gamma-secretase modulator gamma-secretase modulators Wikipedia Wikipedia:Gamma_secretase ChEBI: gamma-secretase modulator ChEBI: Gamma-secretase modulators ChEBI: gamma secretase modulators ChEBI: gamma-secretase modulators ChEBI: Gamma-secretase modulator ChEBI: gamma secretase modulator antifibrinolytic drug A drug that prevent fibrinolysis or lysis of a blood clot or thrombus. CHEBI:48675 antifibrinolytic agent antifibrinolytic agents antifibrinolytic drugs chebi_ontology ChEBI: antifibrinolytic agents ChEBI: antifibrinolytic drugs ChEBI: antifibrinolytic agent fibrin modulating drug A drug that affects the function of fibrin in blood coagulation. CHEBI:48676 chebi_ontology fibrin modulating agent fibrin modulating agents fibrin modulating drugs ChEBI: fibrin modulating agents ChEBI: fibrin modulating agent ChEBI: fibrin modulating drugs agonist CHEBI:48705 Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own. agonist agonista agoniste agonists chebi_ontology ChEBI: agonists ChEBI: agonista IUPAC: agonist ChEBI: agoniste antagonist CHEBI:48706 Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. antagonist antagonista antagoniste antagonists chebi_ontology ChEBI: antagonista ChEBI: antagonists IUPAC: antagonist ChEBI: antagoniste cholinergic antagonist Anticholinergika Anticholinergikum Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists. CHEBI:48873 acetylcholine antagonists acetylcholine receptor antagonist agent anticholinergique agente anticolinergico agentes anticolinergicos anticholinergic agents anticholinergics anticholinergiques anticolinergicos chebi_ontology cholinergic-blocking agents Anticholinergikum ChEBI: ChEBI: anticholinergics ChEBI: agent anticholinergique IUPHAR: acetylcholine receptor antagonist ChEBI: anticolinergicos Anticholinergika ChEBI: ChEBI: anticholinergic agents ChEBI: anticholinergiques ChEBI: cholinergic-blocking agents ChEBI: acetylcholine antagonists ChEBI: agentes anticolinergicos ChEBI: agente anticolinergico muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. Antimuskarinika Antimuskarinikum CHEBI:48876 agente antimuscarinico agentes antimuscarinicos agents antimuscariniques antimuscarinic agents antimuscarinicos chebi_ontology muscarinic acetylcholine receptor antagonist muscarinic antagonists ChEBI: antimuscarinicos ChEBI: agents antimuscariniques ChEBI: agentes antimuscarinicos Antimuskarinikum ChEBI: ChEBI: agente antimuscarinico ChEBI: muscarinic antagonists Antimuskarinika ChEBI: ChEBI: muscarinic acetylcholine receptor antagonist ChEBI: antimuscarinic agents nicotinic antagonist An antagonist at the nicotinic cholinergic receptor. CHEBI:48878 agente antinicotinico agentes antinicotinicos agents antinicotiniques antinicotinicos chebi_ontology nicotinic antagonists nicotinic cholinergic agonist ChEBI: antinicotinicos ChEBI: nicotinic cholinergic agonist ChEBI: agentes antinicotinicos ChEBI: agente antinicotinico ChEBI: agents antinicotiniques ChEBI: nicotinic antagonists bile acid metabolite CHEBI:48887 Metabolites of bile acids, four-ringed steroid acids formed along the cholesterol degradation pathway. bile acid metabolites bile salt metabolite chebi_ontology ChEBI: bile salt metabolite ChEBI: bile acid metabolites hormone antagonist A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. CHEBI:49020 chebi_ontology hormone antagonists ChEBI: hormone antagonists prostaglandin antagonist A compound that inhibits the action of prostaglandins. CHEBI:49023 Wikipedia:Prostaglandin_antagonist chebi_ontology prostaglandin inhibitor Wikipedia Wikipedia:Prostaglandin_antagonist ChEBI: prostaglandin inhibitor drug metabolite CHEBI:49103 chebi_ontology drug metabolites ChEBI: drug metabolites peripheral nervous system drug A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system. CHEBI:49110 chebi_ontology peripheral nervous system agent peripheral nervous system drugs ChEBI: peripheral nervous system agent ChEBI: peripheral nervous system drugs leukotriene antagonist A drug designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level. CHEBI:49159 LTRA chebi_ontology leukotriene antagonists leukotriene receptor antagonist leukotriene receptor antagonists ChEBI: leukotriene receptor antagonist ChEBI: leukotriene receptor antagonists DrugBank: LTRA ChEBI: leukotriene antagonists anti-asthmatic drug A drug used to treat asthma. CHEBI:49167 anti-asthmatic agent anti-asthmatic agents anti-asthmatic drugs chebi_ontology ChEBI: anti-asthmatic agents ChEBI: anti-asthmatic drugs ChEBI: anti-asthmatic agent proton pump inhibitor A compound that inhibits H(+)--K(+)-exchanging ATPase. CHEBI:49200 chebi_ontology proton pump inhibitors ChEBI: proton pump inhibitors anti-ulcer drug CHEBI:49201 One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. anti-ulcer agent anti-ulcer agents anti-ulcer drugs chebi_ontology ChEBI: anti-ulcer agents ChEBI: anti-ulcer drugs ChEBI: anti-ulcer agent CETP inhibitor Any inhibitor of cholesterylester transfer protein (CETP), which transfers cholesterol from high density lipoproteins (HDL, the 'good' cholesterol-containing particles) to low or very low density lipoproteins (LDL or VLDL, the 'bad' cholesterol-containing particles). Inhibition of this process results in higher HDL levels and lower LDL levels. CETP inhibitors are under investigation as potential drugs to reduce the risk of arteriosclerotic vascular disease (atherosclerosis). CETP inhibitors CHEBI:49205 Wikipedia:CETP_inhibitor chebi_ontology cholesteryl ester transfer protein inhibitor CETP inhibitors ChEBI: ChEBI: cholesteryl ester transfer protein inhibitor Wikipedia Wikipedia:CETP_inhibitor contraceptive drug A chemical substance that prevents or reduces the probability of conception. CHEBI:49323 chebi_ontology contraceptive agent contraceptive drugs ChEBI: contraceptive agent ChEBI: contraceptive drugs female contraceptive drug A chemical substance or agent with contraceptive activity in females. CHEBI:49324 chebi_ontology female contraceptive agent female contraceptive drugs ChEBI: female contraceptive agent ChEBI: female contraceptive drugs oral contraceptive A compound, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. CHEBI:49325 chebi_ontology oral contraceptives ChEBI: oral contraceptives synthetic oral contraceptive An oral contraceptive which owes its effectiveness to synthetic preparation. CHEBI:49326 chebi_ontology synthetic oral contraceptives ChEBI: synthetic oral contraceptives excitatory amino acid agonist An agent that binds to and activates excitatory amino acid receptors. CHEBI:50103 chebi_ontology excitatory amino acid agonists excitatory amino acid receptor agonist excitatory amino acid receptor agonists ChEBI: excitatory amino acid receptor agonist ChEBI: excitatory amino acid receptor agonists ChEBI: excitatory amino acid agonists sex hormone Any hormone that is responsible for controlling sexual characteristics and reproductive function. CHEBI:50112 Geschlechtshormon Geschlechtshormone Sexualhormon Sexualhormone chebi_ontology hormone sexuelle hormones sexuelles sex hormones ChEBI: hormones sexuelles ChEBI: Geschlechtshormone ChEBI: Sexualhormon ChEBI: Geschlechtshormon ChEBI: Sexualhormone ChEBI: hormone sexuelle ChEBI: sex hormones mu-opioid receptor antagonist CHEBI:50137 chebi_ontology bronchoconstrictor agent A drug which causes a narrowing of the lumen of a bronchus or bronchiole. CHEBI:50141 bronchoconstrictor agents bronchoconstrictor drug chebi_ontology ChEBI: bronchoconstrictor drug ChEBI: bronchoconstrictor agents keratolytic drug A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases. CHEBI:50176 chebi_ontology desquamating agent keratolytic agent keratolytic drugs skin-peeling agent ChEBI: desquamating agent ChEBI: keratolytic agent ChEBI: keratolytic drugs ChEBI: skin-peeling agent dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. CHEBI:50177 chebi_ontology dermatologic agent dermatologic drugs dermatological agent ChEBI: dermatologic drugs ChEBI: dermatologic agent ChEBI: dermatological agent P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. CHEBI:50183 P450 inhibitors chebi_ontology cytochrome P450 inhibitor ChEBI: cytochrome P450 inhibitor ChEBI: P450 inhibitors ion transport inhibitor A compound which inhibits the movement of an ion across an energy-transducing cell membrane. CHEBI:50184 chebi_ontology ion transport inhibitors ion-transport inhibitor ion-transport inhibitors ChEBI: ion-transport inhibitor ChEBI: ion-transport inhibitors ChEBI: ion transport inhibitors fatty acid synthesis inhibitor CHEBI:50185 chebi_ontology provitamin CHEBI:50188 chebi_ontology phosphodiesterase inhibitor CHEBI:50218 Compound which inhibits or antagonizes the biosynthesis or actions of phosphodiesterases. chebi_ontology phosphodiesterase inhibitors ChEBI: phosphodiesterase inhibitors cholinesterase reactivator A drug used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. CHEBI:50241 chebi_ontology cholinesterase reactivators ChEBI: cholinesterase reactivators enzyme reactivator CHEBI:50242 CiteXplore:15551381 CiteXplore:16763789 CiteXplore:8415873 Compound which restore enzymatic activity by removing an inhibitory group bound to the reactive site of the enzyme. chebi_ontology enzyme reactivators PubMed citation CiteXplore:15551381 ChEBI: enzyme reactivators PubMed citation CiteXplore:8415873 PubMed citation CiteXplore:16763789 antidote Any protective agent counteracting or neutralizing the action of poisons. CHEBI:50247 antidotes chebi_ontology ChEBI: antidotes hematologic agent CHEBI:50248 Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. chebi_ontology hematologic agents ChEBI: hematologic agents anticoagulant An agent that prevents blood clotting. CHEBI:50249 anticoagulante anticoagulants chebi_ontology ChEBI: anticoagulante ChEBI: anticoagulants prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. CHEBI:50266 Prodrugs Wikipedia:Prodrug chebi_ontology Wikipedia Wikipedia:Prodrug ChEBI: Prodrugs protective agent CHEBI:50267 Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent. chebi_ontology chemoprotectant chemoprotectants chemoprotective agent chemoprotective agents protective agents ChEBI: chemoprotective agents ChEBI: chemoprotectant ChEBI: chemoprotectants ChEBI: protective agents ChEBI: chemoprotective agent GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. CHEBI:50268 GABA modulators chebi_ontology ChEBI: GABA modulators alcohol dehydrogenase inhibitor CHEBI:50269 alcohol dehydrogenase inhibitors chebi_ontology ChEBI: alcohol dehydrogenase inhibitors topoisomerase I inhibitor A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. CHEBI:50276 EC 5.99.1.2 inhibitor EC 5.99.1.2 inhibitors chebi_ontology topoisomerase I inhibitors type I DNA topoisomerase inhibitor type I DNA topoisomerase inhibitors ChEBI: EC 5.99.1.2 inhibitors ChEBI: type I DNA topoisomerase inhibitor ChEBI: type I DNA topoisomerase inhibitors ChEBI: topoisomerase I inhibitors ChEBI: EC 5.99.1.2 inhibitor parasympatholytic Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists. CHEBI:50370 chebi_ontology parasympatholytics ChEBI: parasympatholytics ceramide glucosyltransferase inhibitor An enzyme inhibitor that inhibits the activity of ceramide glucosyltransferase (EC 2.4.1.80). CHEBI:50382 CHEBI:75128 CiteXplore:19285492 CiteXplore:21974949 CiteXplore:22918683 EC 2.4.1.80 inhibitor EC 2.4.1.80 inhibitors UDP-glucose:N-acylsphingosine D-glucosyltransferase inhibitor UDP-glucose:N-acylsphingosine D-glucosyltransferase inhibitors UDP-glucose:ceramide glucosyltransferase inhibitor UDP-glucose:ceramide glucosyltransferase inhibitors Wikipedia:Ceramide_glucosyltransferase ceramide glucosyltransferase inhibitors ceramide:UDP-glucose glucosyltransferase inhibitor ceramide:UDP-glucose glucosyltransferase inhibitors ceramide:UDPGlc glucosyltransferase inhibitor ceramide:UDPGlc glucosyltransferase inhibitors chebi_ontology glucosylceramide synthase inhibitor glucosylceramide synthase inhibitors uridine diphosphoglucose-ceramide glucosyltransferase inhibitor uridine diphosphoglucose-ceramide glucosyltransferase inhibitors ChEBI: ceramide glucosyltransferase inhibitors ChEBI: glucosylceramide synthase inhibitor ChEBI: EC 2.4.1.80 inhibitors ChEBI: UDP-glucose:N-acylsphingosine D-glucosyltransferase inhibitors Wikipedia Wikipedia:Ceramide_glucosyltransferase PubMed citation CiteXplore:19285492 ChEBI: UDP-glucose:ceramide glucosyltransferase inhibitors ChEBI: ceramide:UDPGlc glucosyltransferase inhibitors PubMed citation CiteXplore:22918683 ChEBI: UDP-glucose:ceramide glucosyltransferase inhibitor ChEBI: uridine diphosphoglucose-ceramide glucosyltransferase inhibitor ChEBI: EC 2.4.1.80 inhibitor ChEBI: ceramide:UDPGlc glucosyltransferase inhibitor ChEBI: uridine diphosphoglucose-ceramide glucosyltransferase inhibitors ChEBI: glucosylceramide synthase inhibitors ChEBI: ceramide:UDP-glucose glucosyltransferase inhibitor ChEBI: ceramide:UDP-glucose glucosyltransferase inhibitors PubMed citation CiteXplore:21974949 ChEBI: UDP-glucose:N-acylsphingosine D-glucosyltransferase inhibitor NAD(P)H:quinone oxidoreductase inhibitor CHEBI:50390 Compound that inhibits the flavoprotein that reversibly catalyzes the oxidation of NADH or NADPH. DT Diaphorase inhibitor Menadione reductase inhibitor NAD(P)H Dehydrogenase (Quinone) inhibitor Phylloquinone reductase inhibitor Quinone reductase inhibitor Vitamin K reductase inhibitor chebi_ontology ChEBI: NAD(P)H Dehydrogenase (Quinone) inhibitor ChEBI: Quinone reductase inhibitor ChEBI: Vitamin K reductase inhibitor ChEBI: Phylloquinone reductase inhibitor ChEBI: DT Diaphorase inhibitor ChEBI: Menadione reductase inhibitor probe A role played by a molecular entity used to study the microscopic environment. CHEBI:50406 chebi_ontology acid-base indicator An acid or base which exhibits a colour change on neutralization by the basic or acidic titrant at or near the equivalence point of a titration. CHEBI:50407 Saeure-Base-Indikator Saeure-Base-Indikatoren acid-base indicator chebi_ontology indicador acido-base indicateur acide-base IUPAC: acid-base indicator IUPAC: indicateur acide-base ChEBI: Saeure-Base-Indikator IUPAC: indicador acido-base ChEBI: Saeure-Base-Indikatoren visual indicator Anything used in a scientific experiment that gives a visual change to indicate the presence of a substance or quality, change in a body, etc. CHEBI:50408 chebi_ontology indicador visual indicateur visuel visual indicator IUPAC: indicateur visuel IUPAC: indicador visual IUPAC: visual indicator adsorption indicator A substance which is adsorbed or desorbed with concomitant colour change at or near the equivalence point of a titration. CHEBI:50409 adsorption indicator chebi_ontology indicador de adsorcion indicateur par adsorption IUPAC: adsorption indicator IUPAC: indicateur par adsorption IUPAC: indicador de adsorcion colour indicator CHEBI:50410 chebi_ontology colour indicator indicador de color indicateur colore indicateurs colores IUPAC: indicador de color ChEBI: indicateurs colores IUPAC: indicateur colore IUPAC: colour indicator one-colour indicator A colour indicator that is colourless on one side of the transition interval. CHEBI:50411 chebi_ontology indicador monocolor indicador monocromico indicateur monocolore one-colour indicator IUPAC: indicador monocolor IUPAC: indicateur monocolore IUPAC: indicador monocromico IUPAC: one-colour indicator two-colour indicator A colour indicator that possesses a different colour on each side of the transition interval. CHEBI:50412 chebi_ontology indicador bicolor indicateur bicolore two-colour indicator IUPAC: indicateur bicolore IUPAC: indicador bicolor IUPAC: two-colour indicator NADPH oxidase inhibitor CHEBI:50423 NADPH oxidase inhibitors chebi_ontology ChEBI: NADPH oxidase inhibitors platelet aggregation inhibitor A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. CHEBI:50427 chebi_ontology platelet aggregation inhibitors ChEBI: platelet aggregation inhibitors platelet glycoprotein-IIb/IIIa receptor antagonist Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation. CHEBI:50433 GPIIb/IIIa antagonist GPIIb/IIIa antagonists Wikipedia:Glycoprotein_IIb/IIIa_inhibitors chebi_ontology fibrinogen receptor antagonist fibrinogen receptor antagonists glycoprotein-IIb/IIIa receptor antagonist glycoprotein-IIb/IIIa receptor antagonists platelet glycoprotein-IIb/IIIa receptor antagonists ChEBI: GPIIb/IIIa antagonists ChEBI: glycoprotein-IIb/IIIa receptor antagonist ChEBI: fibrinogen receptor antagonists Wikipedia Wikipedia:Glycoprotein_IIb/IIIa_inhibitors ChEBI: GPIIb/IIIa antagonist ChEBI: fibrinogen receptor antagonist ChEBI: platelet glycoprotein-IIb/IIIa receptor antagonists ChEBI: glycoprotein-IIb/IIIa receptor antagonists adenosine phosphodiesterase inhibitor CHEBI:50444 chebi_ontology adenosine deaminase inhibitor ADA inhibitor CHEBI:50445 adenosine deaminase inhibitors chebi_ontology ADA inhibitor ChEBI: ChEBI: adenosine deaminase inhibitors phospholipase A2 inhibitor CHEBI:50469 chebi_ontology phospholipase A2 inhibitors ChEBI: phospholipase A2 inhibitors dihydropteroate synthetase inhibitor A compound or agent that combines with dihydropteroate synthetase, an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. CHEBI:50502 chebi_ontology laxative An agent that produces a soft formed stool, and relax and loosen the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxatives and a cathartic. CHEBI:50503 chebi_ontology laxante laxatives ChEBI: laxante ChEBI: laxatives osmotic diuretic CHEBI:50504 Compound that increase urine volume by increasing the amount of osmotically active solute in the urine. It also increases the osmolarity of plasma. chebi_ontology sweetening agent CHEBI:50505 Substance that sweeten food, beverages, medications, etc. chebi_ontology appetite depressant Agent that is used to decrease appetite. CHEBI:50507 chebi_ontology potassium channel blocker An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions. CHEBI:50509 chebi_ontology potassium channel modulator CHEBI:50510 chebi_ontology mydriatic agent Agent that dilates the pupil. Used in eye diseases and to facilitate eye examination. It may be either a sympathomimetic or parasympatholytic. The latter cause cycloplegia or paralysis of accommodation at high doses and may precipitate glaucoma. CHEBI:50513 chebi_ontology mydriatics ChEBI: mydriatics vasoconstrictor agent CHEBI:50514 Drug used to cause constriction of the blood vessels. chebi_ontology protein denaturant CHEBI:50533 chebi_ontology nitric oxide donor An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide. CHEBI:50566 chebi_ontology phosphodiesterase III inhibitor CHEBI:50568 Compound which selectively inhibits or antagonizes the biosynthesis or actions of phosphodiesterase III (PDE3). chebi_ontology alpha-amylase inhibitor An enzyme inhibitor that interferes with the action of alpha-amylase (EC 3.2.1.1). CHEBI:50627 Wikipedia:Alpha-amylase chebi_ontology Wikipedia Wikipedia:Alpha-amylase alpha-glucoside hydrolase inhibitor CHEBI:50628 chebi_ontology cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor with specificity for cyclooxygenase 2. CHEBI:50629 COX-2 inhibitor COX-2 inhibitors PGHS-2 inhibitor PGHS-2 inhibitors Wikipedia:Prostaglandin-endoperoxide_synthase_2 chebi_ontology cyclo-oxygenase 2 inhibitor cyclo-oxygenase 2 inhibitors cyclo-oxygenase-2 inhibitor cyclo-oxygenase-2 inhibitors cyclooxygenase 2 inhibitors cyclooxygenase-2 inhibitor cyclooxygenase-2 inhibitors prostaglandin H synthase-2 inhibitor prostaglandin H synthase-2 inhibitors prostaglandin-endoperoxide synthase 2 inhibitor prostaglandin-endoperoxide synthase 2 inhibitors ChEBI: prostaglandin-endoperoxide synthase 2 inhibitors Wikipedia Wikipedia:Prostaglandin-endoperoxide_synthase_2 ChEBI: cyclo-oxygenase-2 inhibitors ChEBI: cyclooxygenase-2 inhibitors ChEBI: cyclo-oxygenase 2 inhibitors ChEBI: prostaglandin H synthase-2 inhibitors ChEBI: PGHS-2 inhibitors ChEBI: cyclo-oxygenase-2 inhibitor COX-2 inhibitors ChEBI: COX-2 inhibitor ChEBI: ChEBI: cyclooxygenase-2 inhibitor ChEBI: prostaglandin H synthase-2 inhibitor ChEBI: prostaglandin-endoperoxide synthase 2 inhibitor ChEBI: PGHS-2 inhibitor ChEBI: cyclo-oxygenase 2 inhibitor ChEBI: cyclooxygenase 2 inhibitors cyclooxygenase 1 inhibitor A cyclooxygenase inhibitor with specificity for cyclooxygenase 1. CHEBI:50630 COX-1 inhibitor COX-1 inhibitors PTGS1 inhibitor PTGS1 inhibitors Wikipedia:PTGS1 chebi_ontology cyclo-oxygenase 1 inhibitor cyclo-oxygenase 1 inhibitors cyclooxygenase 1 inhibitors cyclooxygenase-1 inhibitor cyclooxygenase-1 inhibitors prostaglandin G/H synthase 1 inhibitor prostaglandin G/H synthase 1 inhibitors prostaglandin H2 synthase 1 inhibitor prostaglandin H2 synthase 1 inhibitors prostaglandin-endoperoxide synthase 1 inhibitor prostaglandin-endoperoxide synthase 1 inhibitors ChEBI: prostaglandin H2 synthase 1 inhibitor ChEBI: PTGS1 inhibitors ChEBI: prostaglandin G/H synthase 1 inhibitor ChEBI: prostaglandin H2 synthase 1 inhibitors Wikipedia Wikipedia:PTGS1 ChEBI: prostaglandin G/H synthase 1 inhibitors ChEBI: cyclooxygenase 1 inhibitors ChEBI: PTGS1 inhibitor ChEBI: prostaglandin-endoperoxide synthase 1 inhibitor COX-1 inhibitors ChEBI: ChEBI: prostaglandin-endoperoxide synthase 1 inhibitors ChEBI: cyclo-oxygenase 1 inhibitors ChEBI: cyclo-oxygenase 1 inhibitor ChEBI: cyclooxygenase-1 inhibitor COX-1 inhibitor ChEBI: ChEBI: cyclooxygenase-1 inhibitors urease inhibitor CHEBI:50635 Compound that, by one mechanism or another, interferes with urease activity and reduces urea hydrolysis. chebi_ontology farnesyl pyrophosphate synthetase inhibitor CHEBI:50643 chebi_ontology bone density conservation agent An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis. CHEBI:50646 CHEBI:72497 Wikipedia:Osteoporosis anti-osteopenia agent anti-osteopenia agents anti-osteopenia drug anti-osteopenia drugs anti-osteoporosis agent anti-osteoporosis agents anti-osteoporosis drug anti-osteoporosis drugs anti-osteoporotic anti-osteoporotic agent anti-osteoporotic agents anti-osteoporotic drug anti-osteoporotic drugs anti-osteoporotics antiosteoporotic antiosteoporotics bone density conservation agents bone density conservation drug bone density conservation drugs chebi_ontology Wikipedia Wikipedia:Osteoporosis ChEBI: anti-osteoporotic agents ChEBI: antiosteoporotic ChEBI: anti-osteoporosis agent ChEBI: anti-osteoporotic agent ChEBI: anti-osteopenia agents ChEBI: anti-osteoporosis drugs ChEBI: anti-osteoporotic drugs ChEBI: bone density conservation drug ChEBI: anti-osteoporotics ChEBI: anti-osteoporosis drug ChEBI: antiosteoporotics ChEBI: anti-osteopenia agent ChEBI: bone density conservation drugs ChEBI: anti-osteoporotic ChEBI: anti-osteopenia drug ChEBI: anti-osteopenia drugs ChEBI: bone density conservation agents ChEBI: anti-osteoporotic drug ChEBI: anti-osteoporosis agents matrix metalloproteinase inhibitor CHEBI:50664 MMPI chebi_ontology matrix metalloproteinase inhibitors ChEBI: MMPI ChEBI: matrix metalloproteinase inhibitors antithyroid drug A drug used to treat hyperthyroidism by reducing the excessive production of thyroid hormones. CHEBI:50671 antithyroid agent antithyroid agents antithyroid drugs chebi_ontology ChEBI: antithyroid drugs ChEBI: antithyroid agent ChEBI: antithyroid agents dihydrofolate reductase inhibitor 7,8-dihydrofolate reductase inhibitor 7,8-dihydrofolate reductase inhibitors Any compound that inhibits the action of dihydrofolate reductase (EC 1.5.1.3). CHEBI:50683 DHFR inhibitor DHFR inhibitors EC 1.5.1.3 inhibitor EC 1.5.1.3 inhibitors NADPH-dihydrofolate reductase inhibitor NADPH-dihydrofolate reductase inhibitors Wikipedia:Dihydrofolate_reductase_inhibitor chebi_ontology dihydrofolate reductase inhibitors dihydrofolic acid reductase inhibitor dihydrofolic acid reductase inhibitors dihydrofolic reductase inhibitor dihydrofolic reductase inhibitors folic acid reductase inhibitor folic acid reductase inhibitors folic reductase inhibitor folic reductase inhibitors tetrahydrofolate dehydrogenase inhibitor tetrahydrofolate dehydrogenase inhibitors Wikipedia Wikipedia:Dihydrofolate_reductase_inhibitor ChEBI: folic acid reductase inhibitors 7,8-dihydrofolate reductase inhibitors ChEBI: ChEBI: dihydrofolate reductase inhibitors ChEBI: DHFR inhibitors ChEBI: NADPH-dihydrofolate reductase inhibitor ChEBI: dihydrofolic acid reductase inhibitor ChEBI: dihydrofolic acid reductase inhibitors ChEBI: tetrahydrofolate dehydrogenase inhibitor ChEBI: folic acid reductase inhibitor ChEBI: DHFR inhibitor ChEBI: folic reductase inhibitors ChEBI: tetrahydrofolate dehydrogenase inhibitors 7,8-dihydrofolate reductase inhibitor ChEBI: ChEBI: dihydrofolic reductase inhibitors ChEBI: EC 1.5.1.3 inhibitors ChEBI: NADPH-dihydrofolate reductase inhibitors ChEBI: dihydrofolic reductase inhibitor ChEBI: EC 1.5.1.3 inhibitor ChEBI: folic reductase inhibitor cross-linking reagent A reagent with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between macromolecules, principally side chains of amino acids in proteins, allowing the locations of naturally reactive areas within the proteins to be identified. CHEBI:50684 chebi_ontology cross-linking reagents ChEBI: cross-linking reagents antitrichomonal drug A drug used to treat trichomonas infections. CHEBI:50685 antitrichomonal agent chebi_ontology ChEBI: antitrichomonal agent reproductive control drug A substance used either in the prevention or facilitation of pregnancy. CHEBI:50689 chebi_ontology reproductive control agent reproductive control drugs ChEBI: reproductive control drugs ChEBI: reproductive control agent abortifacient A chemical substance that interrupts pregnancy after implantation. CHEBI:50691 Wikipedia:Abortifacient abortifacient agent abortifacient agents abortifacient drug abortifacient drugs abortifacients chebi_ontology ChEBI: abortifacients Wikipedia Wikipedia:Abortifacient ChEBI: abortifacient drugs ChEBI: abortifacient drug ChEBI: abortifacient agents ChEBI: abortifacient agent penicillin binding protein 3 inhibitor An agent that inhibits penicillin binding protein 3 (PBP3), a bacterial protein that binds irreversibly to penicillins and other antibacterial agents derived from lactams. The penicillin-binding proteins are primarily enzymes involved in cell wall biosynthesis. CHEBI:50696 PBP3 inhibitor chebi_ontology ChEBI: PBP3 inhibitor nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. CHEBI:50733 Dietary Supplement Food Supplementation Nutritional supplement chebi_ontology ChEBI: Food Supplementation ChEBI: Nutritional supplement ChEBI: Dietary Supplement estrogen receptor modulator A substance that possess antiestrogenic actions but can also produce estrogenic effects as well. It acts as complete or partial agonist or as antagonist. It can be either steroidal or nonsteroidal in structure. CHEBI:50739 chebi_ontology retinoic acid receptor alpha/beta agonist CHEBI:50741 chebi_ontology progestogen A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone. CHEBI:50745 chebi_ontology gestagen gestagens progestagen progestagens progestogens ChEBI: gestagen ChEBI: progestogens ChEBI: progestagens ChEBI: progestagen ChEBI: gestagens antipsoriatic A drug used to treat psoriasis. CHEBI:50748 antipsoriatic agent antipsoriatic drug chebi_ontology ChEBI: antipsoriatic agent ChEBI: antipsoriatic drug topoisomerase II inhibitor A topoisomerase inhibitor that inhibits DNA topoisomerase II (EC 5.99.1.3), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. CHEBI:50234 CHEBI:50750 DNA topoisomerase (ATP-hydrolysing) inhibitor DNA topoisomerase (ATP-hydrolysing) inhibitors DNA topoisomerase II inhibitor DNA topoisomerase II inhibitors EC 5.99.1.3 inhibitor EC 5.99.1.3 inhibitors chebi_ontology inhibitor of type II topoisomerase inhibitors of type II topoisomerase topoisomerase II inhibitors topoisomerase-II inhibitor topoisomerase-II inhibitors type II DNA topoisomerase inhibitor type II DNA topoisomerase inhibitors ChEBI: EC 5.99.1.3 inhibitors ChEBI: inhibitor of type II topoisomerase ChEBI: topoisomerase II inhibitors ChEBI: type II DNA topoisomerase inhibitor ChEBI: topoisomerase-II inhibitors ChEBI: inhibitors of type II topoisomerase ChEBI: type II DNA topoisomerase inhibitors ChEBI: DNA topoisomerase (ATP-hydrolysing) inhibitor ChEBI: DNA topoisomerase II inhibitor ChEBI: DNA topoisomerase II inhibitors ChEBI: EC 5.99.1.3 inhibitor ChEBI: topoisomerase-II inhibitor ChEBI: DNA topoisomerase (ATP-hydrolysing) inhibitors anti-estrogen A drug which acts to reduce estrogenic activity in the body, either by reducing the amount of estrogen or by reducing the activity of whatever estrogen is present. CHEBI:50751 anti-estrogenic agent anti-estrogenic drug antiestrogen antiestrogenic agent antiestrogenic drug chebi_ontology ChEBI: antiestrogen ChEBI: antiestrogenic drug ChEBI: anti-estrogenic agent ChEBI: antiestrogenic agent ChEBI: anti-estrogenic drug appetite enhancer A drug which increases appetite. CHEBI:50779 Wikipedia:Appetite_stimulants appetite enhancing drug appetite stimulant chebi_ontology orexigenic ChEBI: appetite enhancing drug Wikipedia Wikipedia:Appetite_stimulants ChEBI: appetite stimulant ChEBI: orexigenic appetite regulator CHEBI:50780 chebi_ontology 5alpha-reductase inhibitor 5alpha-reductase inhibitors CHEBI:50781 Inhibitor of 5alpha-reductase, the enzyme which converts testosterone (CHEBI:17347) into the more potent androgen 5alpha-dihydrotestosterone. Wikipedia:5-alpha-reductase_inhibitor chebi_ontology 5alpha-reductase inhibitors ChEBI: Wikipedia Wikipedia:5-alpha-reductase_inhibitor 3beta-hydroxysteroid dehydrogenase inhibitor 3beta-HSD 3beta-hydroxysteroid dehydrogenase CHEBI:50788 Inhibitor of 3beta-hydroxysteroid dehydrogenase (EC 1.1.1.210), a group of steroidogenic enzymes. chebi_ontology 3beta-HSD ChEBI: 3beta-hydroxysteroid dehydrogenase ChEBI: aromatase inhibitor A compound that inhibits aromatase in order to reduce production of estrogenic steroid hormones. CHEBI:50790 Wikipedia:Aromatase_inhibitor aromatase inhibitors chebi_ontology estrogen synthase inhibitor estrogen synthase inhibitors estrogen synthetase inhibitor estrogen synthetase inhibitors oestrogen synthase inhibitor oestrogen synthase inhibitors oestrogen synthetase inhibitor oestrogen synthetase inhibitors ChEBI: estrogen synthase inhibitor ChEBI: oestrogen synthetase inhibitors ChEBI: oestrogen synthetase inhibitor ChEBI: oestrogen synthase inhibitor ChEBI: estrogen synthetase inhibitors ChEBI: estrogen synthase inhibitors Wikipedia Wikipedia:Aromatase_inhibitor ChEBI: oestrogen synthase inhibitors ChEBI: estrogen synthetase inhibitor ChEBI: aromatase inhibitors estrogen receptor antagonist An antagonist at the estrogen receptor. CHEBI:50792 chebi_ontology estrogen receptor antagonists ChEBI: estrogen receptor antagonists antiparathyroid drug A drug used to treat hyperparathyroidism by reducing the excessive production of parathyroid hormones. CHEBI:50827 antiparathyroid agent antiparathyroid agents antiparathyroid drugs chebi_ontology ChEBI: antiparathyroid agents ChEBI: antiparathyroid drugs ChEBI: antiparathyroid agent estrogen antagonist A compound which inhibits or antagonises the biosynthesis or actions of estrogens. CHEBI:50837 chebi_ontology oestrogen antagonist ChEBI: oestrogen antagonist antimineralocorticoid A compound which inhibits or antagonizes the biosynthesis or actions of mineralocorticoids, a class of steroid hormones characterised by their similarity to aldosterone and their influence on salt and water balance. CHEBI:50843 chebi_ontology aldosterone antagonist CHEBI:50844 chebi_ontology immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. Biomodulator CHEBI:50846 Immune factor Immunologic factor Immunological factor Wikipedia:Immunotherapy chebi_ontology immunomodulators ChEBI: immunomodulators Biomodulator ChEBI: Wikipedia Wikipedia:Immunotherapy ChEBI: Immunologic factor ChEBI: Immunological factor ChEBI: Immune factor immunological adjuvant A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity. CHEBI:50847 Immunoactivator Immunoadjuvant Immunologic adjuvant Immunopotentiator Immunostimulant Wikipedia:Immunologic_adjuvant chebi_ontology Wikipedia Wikipedia:Immunologic_adjuvant ChEBI: Immunoadjuvant ChEBI: Immunopotentiator ChEBI: Immunologic adjuvant ChEBI: Immunostimulant ChEBI: Immunoactivator antiatherogenic agent CHEBI:50855 chebi_ontology anti-allergic agent A drug used to treat allergic reactions. CHEBI:50857 anti-allergic agents anti-allergic drug anti-allergic drugs chebi_ontology ChEBI: anti-allergic drugs ChEBI: anti-allergic drug ChEBI: anti-allergic agents insulin-sensitizing drug An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma). CHEBI:50864 PPAR-gamma agonist PPAR-gamma agonists PPARgamma agonist PPARgamma agonists chebi_ontology glitazonas glitazone drug glitazones insulin sensitisers insulin sensitizers insulin-sensitising drug insulin-sensitizing agent peroxisome proliferator-activated receptor gamma agonist peroxisome proliferator-activated receptor gamma agonists proliferator activated receptor gamma agonist proliferator activated receptor gamma agonists thiazolidinediones tiazolidinedionas ChEBI: PPAR-gamma agonist ChEBI: PPARgamma agonist ChEBI: glitazonas ChEBI: insulin sensitisers ChEBI: tiazolidinedionas ChEBI: glitazones ChEBI: insulin-sensitizing agent ChEBI: glitazone drug ChEBI: proliferator activated receptor gamma agonist ChEBI: insulin-sensitising drug ChEBI: peroxisome proliferator-activated receptor gamma agonist ChEBI: PPAR-gamma agonists ChEBI: thiazolidinediones ChEBI: proliferator activated receptor gamma agonists ChEBI: insulin sensitizers ChEBI: peroxisome proliferator-activated receptor gamma agonists ChEBI: PPARgamma agonists genotoxin A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells. CHEBI:50902 Wikipedia:Genotoxicity chebi_ontology genotoxic agent genotoxic agents genotoxins ChEBI: genotoxic agents ChEBI: genotoxins Wikipedia Wikipedia:Genotoxicity ChEBI: genotoxic agent carcinogenic agent A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. CHEBI:50903 agente carcinogeno cancerigene cancerogene carcinogen carcinogene carcinogenic agents carcinogeno carcinogens chebi_ontology ChEBI: carcinogeno ChEBI: carcinogenic agents ChEBI: carcinogens ChEBI: cancerogene ChEBI: cancerigene ChEBI: carcinogen ChEBI: carcinogene ChEBI: agente carcinogeno allergenic agent A role played by a chemical compound in the onset of allergic reaction and interacting with molecular pathways involved in allergy. CHEBI:50904 alergeno allergen allergene chebi_ontology ChEBI: alergeno ChEBI: allergen ChEBI: allergene teratogenic agent A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect. CHEBI:50905 agent teratogene chebi_ontology teratogen teratogeno ChEBI: teratogen ChEBI: teratogeno ChEBI: agent teratogene role A role is particular behaviour which a material entity may exhibit. CHEBI:50906 chebi_ontology deaminating agent A deaminating agent is a role played by a chemical agent which exhibits the capability of causing the loss of an amine functional group on another molecular entity (e.g. DNA or protein). CHEBI:50907 chebi_ontology hepatotoxic agent A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals. CHEBI:50908 agente hepatotoxico chebi_ontology hepatotoxicant hepatoxic agent hepatoxicant ChEBI: hepatotoxicant ChEBI: hepatoxicant ChEBI: hepatoxic agent ChEBI: agente hepatotoxico nephrotoxic agent A role played by a chemical compound exihibiting itself through the ability to induce damage to the kidney in animals. CHEBI:50909 agente nefrotoxico chebi_ontology nephrotoxicant ChEBI: nephrotoxicant ChEBI: agente nefrotoxico neurotoxin A poison that interferes with the functions of the nervous system. CHEBI:50910 CHEBI:50911 Wikipedia:Neurotoxin agente neurotoxico chebi_ontology nerve poison nerve poisons neurotoxic agent neurotoxic agents neurotoxicant neurotoxins ChEBI: nerve poisons ChEBI: neurotoxins ChEBI: agente neurotoxico ChEBI: neurotoxic agent ChEBI: neurotoxic agents Wikipedia Wikipedia:Neurotoxin ChEBI: neurotoxicant ChEBI: nerve poison cardiotoxic agent A role played by a chemical compound exihibiting itself through the ability to induce damage to the heart and cardiomyocytes. CHEBI:50912 cardiotoxicant chebi_ontology ChEBI: cardiotoxicant fixative A role played by a chemical compound or a mixture of chemical exhibiting itselef through the ability to cause tissue or entities derived from organism to become fixated to a surface or substratum. CHEBI:50913 chebi_ontology fixating agent fixating agents fixation agent ChEBI: fixating agents ChEBI: fixating agent ChEBI: fixation agent phosphatidylinositol-3-OH kinase inhibitor 1-phosphatidylinositol 3-kinase inhibitor An inhibitor of phosphatidylinositol-3-OH kinases, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol. CHEBI:50914 PI(3)K inhibitor PI-3 kinase inhibitor PI3K inhibitor chebi_ontology phosphoinositide 3-kinase inhibitor 1-phosphatidylinositol 3-kinase inhibitor ChEBI: ChEBI: PI(3)K inhibitor ChEBI: phosphoinositide 3-kinase inhibitor ChEBI: PI3K inhibitor ChEBI: PI-3 kinase inhibitor lipid kinase inhibitor An agent that inhibits lipid kinases. CHEBI:50916 chebi_ontology lipid kinase inhibitors ChEBI: lipid kinase inhibitors antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centers (the vomiting center and the chemoreceptive trigger zone) or affect the peripheral receptors. CHEBI:50919 antiemetico antiemetics chebi_ontology ChEBI: antiemetics ChEBI: antiemetico non-specific serine/threonine protein kinase inhibitor A-kinase inhibitor A-kinase inhibitors AP50 kinase inhibitor AP50 kinase inhibitors ATP-protein transphosphorylase inhibitor ATP-protein transphosphorylase inhibitors ATP:protein phosphotransferase (non-specific) inhibitor ATP:protein phosphotransferase (non-specific) inhibitors An agent that inhibits the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine. CHEBI:50925 CHEBI:75764 CK-2 inhibitor CK-2 inhibitors CKI inhibitor CKI inhibitors CKII inhibitor CKII inhibitors EC 2.7.11.1 inhibitor EC 2.7.11.1 inhibitors HIPK2 inhibitor HIPK2 inhibitors Hpr kinase inhibitor Hpr kinase inhibitors M phase-specific cdc2 kinase inhibitor M phase-specific cdc2 kinase inhibitors PKA inhibitor PKA inhibitors Prp4 protein kinase inhibitor Prp4 protein kinase inhibitors Raf kinase inhibitor Raf kinase inhibitors Raf-1 inhibitor Raf-1 inhibitors STK32 inhibitor STK32 inhibitors T-antigen kinase inhibitor T-antigen kinase inhibitors WEE1Hu inhibitor WEE1Hu inhibitors Wee 1-like kinase inhibitor Wee 1-like kinase inhibitors Wee-kinase inhibitor Wee-kinase inhibitors betaIIPKC inhibitor betaIIPKC inhibitors cAMP-dependent protein kinase A inhibitor cAMP-dependent protein kinase A inhibitors cAMP-dependent protein kinase inhibitor cAMP-dependent protein kinase inhibitors cGMP-dependent protein kinase inhibitor cGMP-dependent protein kinase inhibitors calcium-dependent protein kinase C inhibitor calcium-dependent protein kinase C inhibitors calcium/phospholipid-dependent protein kinase inhibitor calcium/phospholipid-dependent protein kinase inhibitors casein kinase (phosphorylating) inhibitor casein kinase (phosphorylating) inhibitors casein kinase 2 inhibitor casein kinase 2 inhibitors casein kinase I inhibitor casein kinase I inhibitors casein kinase II inhibitor casein kinase II inhibitors casein kinase inhibitor casein kinase inhibitors chebi_ontology cyclic AMP-dependent protein kinase A inhibitor cyclic AMP-dependent protein kinase A inhibitors cyclic AMP-dependent protein kinase inhibitor cyclic AMP-dependent protein kinase inhibitors cyclic monophosphate-dependent protein kinase inhibitor cyclic monophosphate-dependent protein kinase inhibitors cyclic nucleotide-dependent protein kinase inhibitor cyclic nucleotide-dependent protein kinase inhibitors cyclin-dependent kinase inhibitor cyclin-dependent kinase inhibitors dsk1 inhibitor dsk1 inhibitors epsilon PKC inhibitor epsilon PKC inhibitors glycogen synthase a kinase inhibitor glycogen synthase a kinase inhibitors glycogen synthase kinase inhibitor glycogen synthase kinase inhibitors hydroxyalkyl-protein kinase inhibitor hydroxyalkyl-protein kinase inhibitors mitogen-activated S6 kinase inhibitor mitogen-activated S6 kinase inhibitors non-specific serine/threonine protein kinase inhibitors p82 kinase inhibitor p82 kinase inhibitors phosphorylase b kinase kinase inhibitor phosphorylase b kinase kinase inhibitors protein glutamyl kinase inhibitor protein glutamyl kinase inhibitors protein kinase (phosphorylating) inhibitor protein kinase (phosphorylating) inhibitors protein kinase A inhibitor protein kinase A inhibitors protein kinase CK2 inhibitor protein kinase CK2 inhibitors protein kinase p58 inhibitor protein kinase p58 inhibitors protein phosphokinase inhibitor protein phosphokinase inhibitors protein serine kinase inhibitor protein serine kinase inhibitors protein serine-threonine kinase inhibitor protein serine-threonine kinase inhibitors protein-aspartyl kinase inhibitor protein-aspartyl kinase inhibitors protein-cysteine kinase inhibitor protein-cysteine kinase inhibitors protein-serine kinase inhibitor protein-serine kinase inhibitors protein-serine/threonine kinase inhibitors ribosomal S6 protein kinase inhibitor ribosomal S6 protein kinase inhibitors ribosomal protein S6 kinase II inhibitor ribosomal protein S6 kinase II inhibitors serine kinase inhibitor serine kinase inhibitors serine protein kinase inhibitor serine protein kinase inhibitors serine(threonine) protein kinase inhibitor serine(threonine) protein kinase inhibitors serine-specific protein kinase inhibitor serine-specific protein kinase inhibitors serine/threonine protein kinase inhibitor serine/threonine protein kinase inhibitors threonine-specific protein kinase inhibitor threonine-specific protein kinase inhibitors twitchin kinase inhibitor twitchin kinase inhibitors type-2 casein kinase inhibitor type-2 casein kinase inhibitors ChEBI: protein kinase A inhibitors CKII inhibitors ChEBI: ChEBI: epsilon PKC inhibitors CKI inhibitor ChEBI: ChEBI: type-2 casein kinase inhibitors ChEBI: serine kinase inhibitor ChEBI: Wee 1-like kinase inhibitors ChEBI: type-2 casein kinase inhibitor ChEBI: serine protein kinase inhibitors ChEBI: T-antigen kinase inhibitor AP50 kinase inhibitor ChEBI: ChEBI: casein kinase II inhibitors ChEBI: serine(threonine) protein kinase inhibitor ChEBI: protein serine kinase inhibitors ChEBI: dsk1 inhibitors ChEBI: Raf-1 inhibitor ChEBI: mitogen-activated S6 kinase inhibitors ChEBI: cyclic monophosphate-dependent protein kinase inhibitor ChEBI: protein kinase p58 inhibitors ChEBI: ribosomal protein S6 kinase II inhibitors ChEBI: PKA inhibitors ChEBI: protein kinase CK2 inhibitors ChEBI: protein-serine kinase inhibitor ChEBI: Wee-kinase inhibitors ChEBI: twitchin kinase inhibitors ChEBI: cyclin-dependent kinase inhibitors ChEBI: Wee-kinase inhibitor ChEBI: betaIIPKC inhibitor ChEBI: cAMP-dependent protein kinase inhibitor ChEBI: glycogen synthase a kinase inhibitor ChEBI: protein kinase A inhibitor ChEBI: calcium-dependent protein kinase C inhibitors ChEBI: Prp4 protein kinase inhibitors ChEBI: cyclic nucleotide-dependent protein kinase inhibitors ChEBI: cyclic AMP-dependent protein kinase A inhibitor ChEBI: cAMP-dependent protein kinase A inhibitors ChEBI: cyclic nucleotide-dependent protein kinase inhibitor ChEBI: serine/threonine protein kinase inhibitors ChEBI: cGMP-dependent protein kinase inhibitor ChEBI: protein glutamyl kinase inhibitors ChEBI: glycogen synthase kinase inhibitor ChEBI: serine-specific protein kinase inhibitors ATP-protein transphosphorylase inhibitors ChEBI: ChEBI: protein serine kinase inhibitor ChEBI: WEE1Hu inhibitors ChEBI: protein kinase CK2 inhibitor ChEBI: ribosomal S6 protein kinase inhibitors ChEBI: protein phosphokinase inhibitor ChEBI: p82 kinase inhibitors ATP-protein transphosphorylase inhibitor ChEBI: ChEBI: serine(threonine) protein kinase inhibitors ChEBI: STK32 inhibitor ChEBI: ribosomal protein S6 kinase II inhibitor CKI inhibitors ChEBI: ChEBI: casein kinase 2 inhibitors ChEBI: threonine-specific protein kinase inhibitors ChEBI: protein serine-threonine kinase inhibitor ChEBI: twitchin kinase inhibitor ChEBI: casein kinase inhibitors ChEBI: cyclic AMP-dependent protein kinase inhibitors ChEBI: EC 2.7.11.1 inhibitors ATP:protein phosphotransferase (non-specific) inhibitors ChEBI: ChEBI: Raf kinase inhibitor ChEBI: protein phosphokinase inhibitors ChEBI: cAMP-dependent protein kinase inhibitors ChEBI: Hpr kinase inhibitors ChEBI: glycogen synthase kinase inhibitors ChEBI: phosphorylase b kinase kinase inhibitor ChEBI: betaIIPKC inhibitors ChEBI: STK32 inhibitors ChEBI: Prp4 protein kinase inhibitor ChEBI: glycogen synthase a kinase inhibitors ChEBI: Raf-1 inhibitors A-kinase inhibitors ChEBI: ChEBI: serine protein kinase inhibitor ChEBI: threonine-specific protein kinase inhibitor ChEBI: serine-specific protein kinase inhibitor ChEBI: mitogen-activated S6 kinase inhibitor ChEBI: calcium/phospholipid-dependent protein kinase inhibitor ChEBI: calcium-dependent protein kinase C inhibitor ChEBI: casein kinase I inhibitor ChEBI: casein kinase 2 inhibitor ChEBI: WEE1Hu inhibitor ChEBI: M phase-specific cdc2 kinase inhibitor ChEBI: protein kinase (phosphorylating) inhibitors ChEBI: casein kinase (phosphorylating) inhibitor ChEBI: Raf kinase inhibitors ChEBI: serine/threonine protein kinase inhibitor ChEBI: T-antigen kinase inhibitors ChEBI: hydroxyalkyl-protein kinase inhibitors ChEBI: protein kinase p58 inhibitor ChEBI: serine kinase inhibitors ChEBI: PKA inhibitor ChEBI: phosphorylase b kinase kinase inhibitors A-kinase inhibitor ChEBI: ChEBI: dsk1 inhibitor ChEBI: casein kinase II inhibitor ChEBI: cyclin-dependent kinase inhibitor ChEBI: cyclic AMP-dependent protein kinase A inhibitors ChEBI: calcium/phospholipid-dependent protein kinase inhibitors ChEBI: protein-serine/threonine kinase inhibitors ChEBI: non-specific serine/threonine protein kinase inhibitors CK-2 inhibitors ChEBI: ChEBI: Wee 1-like kinase inhibitor ChEBI: casein kinase (phosphorylating) inhibitors ChEBI: casein kinase inhibitor AP50 kinase inhibitors ChEBI: ChEBI: protein serine-threonine kinase inhibitors ChEBI: EC 2.7.11.1 inhibitor CKII inhibitor ChEBI: ChEBI: cyclic monophosphate-dependent protein kinase inhibitors ChEBI: protein kinase (phosphorylating) inhibitor ChEBI: ribosomal S6 protein kinase inhibitor ChEBI: M phase-specific cdc2 kinase inhibitors ChEBI: HIPK2 inhibitors ChEBI: cAMP-dependent protein kinase A inhibitor ChEBI: p82 kinase inhibitor ChEBI: cGMP-dependent protein kinase inhibitors ChEBI: HIPK2 inhibitor ChEBI: protein-serine kinase inhibitors ChEBI: protein-aspartyl kinase inhibitor ChEBI: protein-cysteine kinase inhibitor ChEBI: Hpr kinase inhibitor ChEBI: protein-cysteine kinase inhibitors ATP:protein phosphotransferase (non-specific) inhibitor ChEBI: ChEBI: protein glutamyl kinase inhibitor ChEBI: cyclic AMP-dependent protein kinase inhibitor ChEBI: casein kinase I inhibitors ChEBI: hydroxyalkyl-protein kinase inhibitor CK-2 inhibitor ChEBI: ChEBI: protein-aspartyl kinase inhibitors ChEBI: epsilon PKC inhibitor angiogenesis modulating agent An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents. CHEBI:50926 chebi_ontology angiogenesis inducing agent An agent that induces or stimulates the physiologic angiogenesis process. CHEBI:50927 chebi_ontology serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. CHEBI:50949 SSRI Wikipedia:Selective_serotonin_reuptake_inhibitor chebi_ontology serotonin reuptake inhibitor Wikipedia Wikipedia:Selective_serotonin_reuptake_inhibitor ChEBI: serotonin reuptake inhibitor ChEBI: SSRI dopamine uptake inhibitor A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake. CHEBI:51039 DARI DRI Wikipedia:Dopamine_uptake_inhibitor chebi_ontology dopamine reuptake inhibitor dopamine reuptake inhibitors dopamine uptake inhibitors ChEBI: dopamine uptake inhibitors ChEBI: dopamine reuptake inhibitor ChEBI: dopamine reuptake inhibitors ChEBI: DRI ChEBI: DARI Wikipedia Wikipedia:Dopamine_uptake_inhibitor hormone agonist A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. CHEBI:51060 chebi_ontology hormone receptor modulator CHEBI:51061 chebi_ontology dopamine agonist A drug that binds to and activates dopamine receptors. Agonista dopaminergico CHEBI:51065 Dopamine receptor agonist Dopaminergic agonist chebi_ontology Agonista dopaminergico ChEBI: ChEBI: Dopamine receptor agonist ChEBI: Dopaminergic agonist miotic Aa agent causing contraction of the pupil of the eye. Because the size of the pupil is under the antagonistic control of the sympathetic and parasympathetic systems, drugs affecting either system can cause miosis. Drugs that mimic or potentiate the parasympathetic input to the circular constrictor muscle and drugs that inhibit sympathetic input to the radial dilator muscle tend to contract the pupils. CHEBI:51068 Miotico chebi_ontology miotics ChEBI: miotics ChEBI: Miotico antifouling biocide A compound that inhibits the growth of marine organisms. Antifoulant Antifouling agent CHEBI:51076 Marine pesticide chebi_ontology ChEBI: Marine pesticide Antifoulant ChEBI: Antifouling agent ChEBI: chemical role A role played by the molecular entity or part thereof within a chemical context. CHEBI:51086 chebi_ontology protecting group A group that is introduced into a molecule by chemical modification of a functional group in order to obtain chemoselectivity in a subsequent chemical reaction. CHEBI:51087 Schutzgruppe Schutzgruppen chebi_ontology groupe protecteur protective group ChEBI: groupe protecteur ChEBI: Schutzgruppe ChEBI: protective group ChEBI: Schutzgruppen fluorescent dye CHEBI:51121 chebi_ontology fluorescent dyes ChEBI: fluorescent dyes Wittig reagent A role played by a phosphonium ylide in a Wittig reaction. CHEBI:51166 Wittig reagents chebi_ontology reactif de Wittig reactivo de Wittig reactivos de Wittig IUPAC: Wittig reagents IUPAC: reactif de Wittig IUPAC: reactivo de Wittig IUPAC: reactivos de Wittig antitussive An agents that suppresses cough. CHEBI:51177 chebi_ontology fluorochrome A fluorescent dye used to stain biological specimens. CHEBI:51217 chebi_ontology fluorochromes ChEBI: fluorochromes Grignard reagent A role played by an organomagnesium halide in a Grignard reaction. CHEBI:51237 Grignards Reagens chebi_ontology ChEBI: Grignards Reagens gelator CHEBI:51266 chebi_ontology swelling agent A role played by a compound in a fluid state in swelling a gel, network, or solid. CHEBI:51267 chebi_ontology drying control chemical additive A role played by a compound that facilitates the rapid drying of gels without their cracking. CHEBI:51268 chebi_ontology muscle relaxant A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis. CHEBI:51371 chebi_ontology muscle relaxants ChEBI: muscle relaxants neuromuscular agent A drug used for its actions on skeletal muscle. CHEBI:51372 chebi_ontology GABA agonist A drug that binds to and activates gamma-aminobutyric acid receptors. CHEBI:51373 chebi_ontology GABA agent A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems. CHEBI:51374 chebi_ontology endothelin receptor antagonist A hormone antagonist that blocks endothelin receptors. CHEBI:51451 ERA chebi_ontology ChEBI: ERA endothelin A receptor antagonist A endothelin receptor antagonist is a drug which selectively blocks endothelin A receptors. CHEBI:51452 chebi_ontology partial prostacyclin agonist A compound which binds and activates the prostacyclin receptor IP1, but has only partial efficacy at the receptor relative to a full agonist. CHEBI:51577 chebi_ontology biochemical role A biological role played by the molecular entity or part thereof within a biochemical context. CHEBI:52206 chebi_ontology biophysical role CHEBI:52208 chebi_ontology aetiopathogenetic role A role played by the molecular entity or part thereof which causes the development of a pathological process. CHEBI:52209 chebi_ontology etiopathogenetic agent etiopathogenetic role ChEBI: etiopathogenetic agent ChEBI: etiopathogenetic role pharmacological role A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties. CHEBI:52210 chebi_ontology physiological role CHEBI:52211 chebi_ontology ligand CHEBI:52214 chebi_ontology photochemical role CHEBI:52215 chebi_ontology photobiochemical role A role played by a molecular entity or part thereof in a photobiochemical process. CHEBI:52216 chebi_ontology pharmaceutical Any substance introduced into a living organism with therapeutic or diagnostic purpose. CHEBI:33293 CHEBI:33294 CHEBI:52217 chebi_ontology farmaco medicament pharmaceuticals ChEBI: pharmaceuticals ChEBI: medicament ChEBI: farmaco squaraine dye An organic dye characterized by an aromatic four-membered ring system derived from squaric acid. CHEBI:52271 chebi_ontology mitogen A chemical substance that encourages a cell to commence cell division, triggering mitosis. CHEBI:52290 chebi_ontology sterol methyltransferase inhibitor An enzyme inhibitor that interferes with the action of sterol methyltransferase. CHEBI:52303 chebi_ontology glycoside hydrolase inhibitor A compound that inhibits glycosidases, enzymes which catalyze the hydrolysis of the glycosidic linkage to generate two smaller sugars. CHEBI:52424 chebi_ontology glycosidase inhibitor glycosidase inhibitors glycoside hydrolase inhibitors ChEBI: glycosidase inhibitors ChEBI: glycosidase inhibitor ChEBI: glycoside hydrolase inhibitors neuraminidase inhibitor An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein, thus preventing the virus from budding from the host cell. CHEBI:52425 Neuraminidase inhibitors chebi_ontology ChEBI: Neuraminidase inhibitors HIV-1 RNase H inhibitor An inhibitor of ribonuclease H, an enzyme required for specific hydrolysis of the RNA strand of an RNA/DNA hybrid. CHEBI:52629 HIV-1 RNase H inhibitors HIV-1 ribonuclease H inhibitor HIV-1 ribonuclease H inhibitors chebi_ontology ChEBI: HIV-1 RNase H inhibitors ChEBI: HIV-1 ribonuclease H inhibitor ChEBI: HIV-1 ribonuclease H inhibitors proteasome inhibitor A drug that blocks the action of proteasomes, cellular complexes that break down proteins. CHEBI:52726 chebi_ontology proteasome inhibitors ChEBI: proteasome inhibitors phosphate protecting group A group that serves to protect a phosphate group in the context of a synthesis. CHEBI:52941 chebi_ontology phosphate protecting groups ChEBI: phosphate protecting groups carboxylic acid protecting group A group that serves to protect a carboxylic acid function in the context of a synthesis. CHEBI:52943 carboxylic acid protecting groups chebi_ontology ChEBI: carboxylic acid protecting groups epitope CHEBI:53000 The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. antigenic determinant chebi_ontology epitope function epitope role ChEBI: antigenic determinant ChEBI: epitope function ChEBI: epitope role adenosine A2A receptor antagonist An antagonist at the A2A receptor. CHEBI:53121 Wikipedia:Adenosine_A2A_receptor adenosine A2A receptor antagonists chebi_ontology ChEBI: adenosine A2A receptor antagonists Wikipedia Wikipedia:Adenosine_A2A_receptor P2Y2 receptor agonist A compound that exhibits agonist activity at the P2Y2 receptor. CHEBI:53142 P2Y2 receptor agonists chebi_ontology ChEBI: P2Y2 receptor agonists tissue adhesive A substance used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses. CHEBI:53337 chebi_ontology tissue adhesives ChEBI: tissue adhesives GHB receptor agonist A drug that binds to and activates gamma-hydroxybutyric acid receptors. CHEBI:53353 GHB receptor agonists chebi_ontology ChEBI: GHB receptor agonists chain carrier CHEBI:53431 The role played by a molecular entity, such as an atom or free radical, which is involved in chain-propagating reactions. chain carriers chebi_ontology ChEBI: chain carriers topoisomerase IV inhibitor A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. CHEBI:53559 chebi_ontology topoisomerase IV inhibitors ChEBI: topoisomerase IV inhibitors diamine oxidase inhibitor A drug that has the ability to block oxidative deamination of naturally occurring diamines. CHEBI:53659 chebi_ontology diamine oxidase inhibitors ChEBI: diamine oxidase inhibitors inosine monophosphate dehydrogenase inhibitor An entity that blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. CHEBI:53746 chebi_ontology inosine monophosphate dehydrogenase inhibitors ChEBI: inosine monophosphate dehydrogenase inhibitors HIV-1 reverse transcriptase inhibitor An entity which inhibits the activity of HIV-1 reverse transcriptase. CHEBI:53756 HIV-1 reverse transcriptase inhibitors chebi_ontology reverse transcriptase inhibitor reverse transcriptase inhibitors ChEBI: reverse transcriptase inhibitor ChEBI: reverse transcriptase inhibitors ChEBI: HIV-1 reverse transcriptase inhibitors antispasmodic drug A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder. CHEBI:53784 antispasmodics chebi_ontology ChEBI: antispasmodics mu-opioid receptor agonist A compound that exhibits agonist activity at the mu-opioid receptor. CHEBI:50136 CHEBI:55322 chebi_ontology mu opioid agonist mu-opioid agonists mu-opioid receptor agonists ChEBI: mu-opioid receptor agonists ChEBI: mu opioid agonist ChEBI: mu-opioid agonists antidiarrhoeal drug Any drug found useful in the symptomatic treatment of diarrhoea. CHEBI:55323 antidiarrheal antidiarrheal agent antidiarrheal agents antidiarrheal drug antidiarrheal drugs antidiarrheals antidiarrhoeal antidiarrhoeal agent antidiarrhoeal agents antidiarrhoeal drugs antidiarrhoeals antiperistaltic antiperistaltic agent antiperistaltic agents antiperistaltic drug antiperistaltic drugs antiperistaltics chebi_ontology ChEBI: antidiarrheal agents ChEBI: antidiarrheal drugs ChEBI: antiperistaltic ChEBI: antidiarrheal agent ChEBI: antiperistaltic drug ChEBI: antidiarrheals ChEBI: antidiarrhoeal agents ChEBI: antiperistaltic agents ChEBI: antidiarrhoeal drugs ChEBI: antiperistaltic agent ChEBI: antidiarrhoeal agent ChEBI: antidiarrheal ChEBI: antidiarrhoeal ChEBI: antidiarrheal drug ChEBI: antidiarrhoeals ChEBI: antiperistaltics ChEBI: antiperistaltic drugs gastrointestinal drug A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion. CHEBI:55324 chebi_ontology gastrointestinal agent gastrointestinal agents gastrointestinal drugs ChEBI: gastrointestinal agents ChEBI: gastrointestinal agent ChEBI: gastrointestinal drugs vitamin K antagonist A class of anticoagulants which act by inhibiting the action of vitamin K. CHEBI:55347 chebi_ontology vitamin K antagonists ChEBI: vitamin K antagonists neurokinin-1 receptor antagonist An antagonist at the neurokinin-1 receptor. CHEBI:55350 chebi_ontology neurokinin-1 receptor antagonists ChEBI: neurokinin-1 receptor antagonists substance P receptor antagonist An antagonist at the substance P receptor. CHEBI:55351 chebi_ontology substance P receptor antagonists ChEBI: substance P receptor antagonists antiseborrheic A drug or agent applied to the skin to control seborrhea or seborrheic dermatitis. CHEBI:59010 antiseborrheic agent antiseborrheic agents antiseborrheic drug antiseborrheics chebi_ontology ChEBI: antiseborrheic agent ChEBI: antiseborrheics ChEBI: antiseborrheic agents ChEBI: antiseborrheic drug acid--amino-acid ligase inhibitor Any inhibitor of an acid--amino-acid ligase (EC 6.3.2.*). CHEBI:59105 acid--amino-acid ligase inhibitors chebi_ontology peptide synthase inhibitor peptide synthase inhibitors ChEBI: peptide synthase inhibitors ChEBI: peptide synthase inhibitor ChEBI: acid--amino-acid ligase inhibitors metalloendopeptidase inhibitor An inhibitor of any metalloendopeptidase (EC 3.4.24.*). CHEBI:59107 chebi_ontology metalloendopeptidase inhibitors ChEBI: metalloendopeptidase inhibitors antigen Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC). CHEBI:59132 antigens chebi_ontology ChEBI: antigens biomarker A substance used as an indicator of a biological state. CHEBI:59163 biological marker chebi_ontology ChEBI: biological marker hapten Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals. CHEBI:59174 CiteXplore:17875790 CiteXplore:17986299 CiteXplore:19101624 CiteXplore:291959 CiteXplore:3782019 chebi_ontology haptens PubMed citation CiteXplore:291959 PubMed citation CiteXplore:3782019 ChEBI: haptens PubMed citation CiteXplore:17986299 PubMed citation CiteXplore:19101624 PubMed citation CiteXplore:17875790 GnRH antagonist A chemical substance which inhibits the function of gonadotrophin-releasing hormone (GnRH). CHEBI:59229 GnRH antagonists chebi_ontology gonadotrophin-releasing hormone antagonist gonadotrophin-releasing hormone antagonists ChEBI: gonadotrophin-releasing hormone antagonists ChEBI: gonadotrophin-releasing hormone antagonist ChEBI: GnRH antagonists serine endopeptidase inhibitor Any inhibitor of a serine endopeptidase (EC 3.4.21.*). CHEBI:5924 chebi_ontology serine endopeptidase inhibitors ChEBI: serine endopeptidase inhibitors kappa-opioid receptor agonist A compound that exhibits agonist activity at the kappa-opioid receptor. CHEBI:59282 chebi_ontology kappa-opioid agonist kappa-opioid receptor agonists ChEBI: kappa-opioid receptor agonists ChEBI: kappa-opioid agonist delta-opioid receptor antagonist A compound that exhibits antagonist activity at the delta-opioid receptor. CHEBI:59283 chebi_ontology delta-opioid antagonist delta-opioid antagonists ChEBI: delta-opioid antagonist ChEBI: delta-opioid antagonists squalene monooxygenase inhibitor Any inhibitor of squalene monooxygenase (EC 1.14.99.7). CHEBI:59285 chebi_ontology squalene 2,3-oxidocyclase inhibitor squalene 2,3-oxidocyclase inhibitors squalene epoxidase inhibitor squalene epoxidase inhibitors squalene hydroxylase inhibitor squalene hydroxylase inhibitors squalene monooxygenase inhibitors squalene oxydocyclase inhibitor squalene oxydocyclase inhibitors squalene-2,3-epoxidase inhibitor squalene-2,3-epoxidase inhibitors squalene-2,3-epoxide cyclase inhibitor squalene-2,3-epoxide cyclase inhibitors ChEBI: squalene-2,3-epoxide cyclase inhibitors ChEBI: squalene hydroxylase inhibitor ChEBI: squalene monooxygenase inhibitors ChEBI: squalene-2,3-epoxide cyclase inhibitor ChEBI: squalene oxydocyclase inhibitor ChEBI: squalene epoxidase inhibitors ChEBI: squalene epoxidase inhibitor ChEBI: squalene-2,3-epoxidase inhibitors ChEBI: squalene oxydocyclase inhibitors ChEBI: squalene 2,3-oxidocyclase inhibitors ChEBI: squalene 2,3-oxidocyclase inhibitor ChEBI: squalene hydroxylase inhibitors ChEBI: squalene-2,3-epoxidase inhibitor aromatic-L-amino-acid decarboxylase inhibitor 5-hydroxytryptophan decarboxylase inhibitor 5-hydroxytryptophan decarboxylase inhibitors Any inhibitor of an aromatic-L-amino-acid decarboxylase (EC 4.1.1.28). CHEBI:59321 DOPA decarboxylase inhibitor DOPA decarboxylase inhibitors L-DOPA decarboxylase inhibitor L-DOPA decarboxylase inhibitors aromatic amino acid decarboxylase inhibitor aromatic amino acid decarboxylase inhibitors aromatic-L-amino-acid decarboxylase inhibitors chebi_ontology hydroxytryptophan decarboxylase inhibitor hydroxytryptophan decarboxylase inhibitors tryptophan decarboxylase inhibitor tryptophan decarboxylase inhibitors ChEBI: tryptophan decarboxylase inhibitor 5-hydroxytryptophan decarboxylase inhibitors ChEBI: 5-hydroxytryptophan decarboxylase inhibitor ChEBI: ChEBI: hydroxytryptophan decarboxylase inhibitor ChEBI: L-DOPA decarboxylase inhibitor ChEBI: aromatic-L-amino-acid decarboxylase inhibitors ChEBI: L-DOPA decarboxylase inhibitors ChEBI: aromatic amino acid decarboxylase inhibitor ChEBI: hydroxytryptophan decarboxylase inhibitors ChEBI: DOPA decarboxylase inhibitor ChEBI: tryptophan decarboxylase inhibitors ChEBI: DOPA decarboxylase inhibitors ChEBI: aromatic amino acid decarboxylase inhibitors dipeptidase inhibitor Any enzyme inhibitor that inhibits the action of a dipeptidase (EC 3.4.13.*). CHEBI:59499 EC 3.4.13.* inhibitor EC 3.4.13.* inhibitors chebi_ontology dipeptidase inhibitors ChEBI: dipeptidase inhibitors ChEBI: EC 3.4.13.* inhibitor ChEBI: EC 3.4.13.* inhibitors DNA synthesis inhibitor Any substance that inhibits the synthesis of DNA. CHEBI:59517 DNA synthesis inhibitors chebi_ontology ChEBI: DNA synthesis inhibitors phosphoantigen Any antigen that is a phosphorylated microbial metabolite which activates an immune response in humans. CHEBI:59544 chebi_ontology phosphoantigens ChEBI: phosphoantigens serine C-palmitoyltransferase inhibitor 3-oxosphinganine synthetase inhibitor 3-oxosphinganine synthetase inhibitors Any compound that inhibits the action of serine palmitoyltransferase (EC 2.3.1.50). CHEBI:59647 EC 2.3.1.50 inhibitor EC 2.3.1.50 inhibitors SPT inhibitor SPT inhibitors Wikipedia:Serine_C-palmitoyltransferase acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitor acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitors chebi_ontology palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitor palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitors serine C-palmitoyltransferase inhibitors serine palmitoyltransferase inhibitor serine palmitoyltransferase inhibitors ChEBI: palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitor ChEBI: EC 2.3.1.50 inhibitor 3-oxosphinganine synthetase inhibitors ChEBI: ChEBI: serine palmitoyltransferase inhibitors ChEBI: acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitor ChEBI: SPT inhibitors Wikipedia Wikipedia:Serine_C-palmitoyltransferase 3-oxosphinganine synthetase inhibitor ChEBI: ChEBI: serine C-palmitoyltransferase inhibitors ChEBI: SPT inhibitor ChEBI: EC 2.3.1.50 inhibitors ChEBI: acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitors ChEBI: serine palmitoyltransferase inhibitor ChEBI: palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitors chitin synthase inhibitor Any compound that inhibits the action of chitin synthase (EC 2.4.1.16). CHEBI:59672 chebi_ontology chitin synthase inhibitors chitin synthesis inhibitor chitin synthesis inhibitors ChEBI: chitin synthase inhibitors ChEBI: chitin synthesis inhibitor ChEBI: chitin synthesis inhibitors vasopressin receptor antagonist Any drug which blocks vasopressin receptors. CHEBI:59680 antidiuretic hormone inhibitor antidiuretic hormone inhibitors arginine vasopressin receptor antagonist arginine vasopressin receptor antagonists argipressin receptor antagonist argipressin receptor antagonists chebi_ontology vasopressin receptor antagonists ChEBI: argipressin receptor antagonist ChEBI: arginine vasopressin receptor antagonist ChEBI: argipressin receptor antagonists ChEBI: arginine vasopressin receptor antagonists ChEBI: antidiuretic hormone inhibitors ChEBI: antidiuretic hormone inhibitor ChEBI: vasopressin receptor antagonists antipruritic drug A drug, usually applied topically, that relieves pruritus (itching). CHEBI:59683 anti-itching drug anti-itching drugs antipruritic agent antipruritic agents antipruritic drugs chebi_ontology ChEBI: antipruritic drugs ChEBI: antipruritic agents ChEBI: anti-itching drugs ChEBI: anti-itching drug ChEBI: antipruritic agent vasopressin receptor agonist Any drug which binds to vasopressin receptors and triggers a response. CHEBI:59727 antidiuretic hormone agonist antidiuretic hormone agonists arginine vasopressin receptor agonist arginine vasopressin receptor agonists argipressin receptor agonist argipressin receptor agonists chebi_ontology vasopressin receptor agonists ChEBI: arginine vasopressin receptor agonist ChEBI: antidiuretic hormone agonist ChEBI: argipressin receptor agonist ChEBI: antidiuretic hormone agonists ChEBI: argipressin receptor agonists ChEBI: vasopressin receptor agonists ChEBI: arginine vasopressin receptor agonists electrophilic reagent A reagent that forms a bond to its reaction partner (the nucleophile) by accepting both bonding electrons from that reaction partner. CHEBI:59739 chebi_ontology electrophile electrophiles electrophilic reagents ChEBI: electrophiles ChEBI: electrophilic reagents ChEBI: electrophile nucleophilic reagent A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons. CHEBI:59740 chebi_ontology nucleophile nucleophiles nucleophilic reagents ChEBI: nucleophiles ChEBI: nucleophilic reagents ChEBI: nucleophile chromatographic reagent A reagent used to improve selectivity in chromatographic analyses or separations, e.g. by formation of a derivative or by modification of the mobile phase. CHEBI:59745 chebi_ontology derivatising reagents derivatizing reagent derivatizing reagents ChEBI: derivatizing reagent ChEBI: derivatising reagents ChEBI: derivatizing reagents bolaamphiphile A surfactant molecule with hydrophilic groups at both ends of a hydrophobic hydrocarbon chain CHEBI:59752 alpha-omega-type surfactant bolaamphiphiles bolaform surfactant bolaphile chebi_ontology ChEBI: bolaform surfactant ChEBI: bolaamphiphiles ChEBI: bolaphile ChEBI: alpha-omega-type surfactant progestin A synthetic progestogen. CHEBI:59826 chebi_ontology progestins ChEBI: progestins antihyperplasia drug A drug used for the treatment of hyperplasia (increaced cell production within an organ or tissue). CHEBI:59844 antihypergenesis drug antihypergenesis drugs antihyperplasia drugs antihyperplastic chebi_ontology ChEBI: antihyperplasia drugs ChEBI: antihyperplastic ChEBI: antihypergenesis drug ChEBI: antihypergenesis drugs depigmentation drug Any drug used to depigment skin, normally by decreasing the excretion of melanin from melanocytes. CHEBI:59864 chebi_ontology depigmentation agent depigmentation agents depigmentation drugs depigmentor depigmentors ChEBI: depigmentation agent ChEBI: depigmentor ChEBI: depigmentation drugs ChEBI: depigmentation agents ChEBI: depigmentors HIV fusion inhibitor A drug which interferes with the binding, fusion and entry of an HIV virion to a human cell. By blocking this step in HIV's replication cycle, such agents slow the progression from HIV infection to AIDS. CHEBI:59886 CiteXplore:22470838 HIV entry inhibitor HIV entry inhibitors HIV fusion inhibitors Wikipedia:Entry_inhibitor chebi_ontology ChEBI: HIV entry inhibitor Wikipedia Wikipedia:Entry_inhibitor ChEBI: HIV entry inhibitors ChEBI: HIV fusion inhibitors PubMed citation CiteXplore:22470838 reverse transcriptase inhibitor An entity which inhibits the activity of reverse transcriptase, a viral DNA polymerase enzyme that retroviruses need to reproduce. CHEBI:59897 RNA-dependent DNA polymerase inhibitor RNA-dependent DNA polymerase inhibitors Wikipedia:Reverse-transcriptase_inhibitor chebi_ontology reverse transcriptase inhibitors ChEBI: RNA-dependent DNA polymerase inhibitors Wikipedia Wikipedia:Reverse-transcriptase_inhibitor ChEBI: RNA-dependent DNA polymerase inhibitor ChEBI: reverse transcriptase inhibitors amphiphile A surfactant molecule possessing both hydrophilic and lipophilic properties. CHEBI:59941 amphiphiles chebi_ontology ChEBI: amphiphiles tyrosinase inhibitor Any inhibitor of tyrosinase (monophenol monooxygenase) (EC 1.14.18.1), an enzyme that catalyses the oxidation of phenols (such as tyrosine) and is widespread in plants and animals. CHEBI:59997 chebi_ontology tyrosinase inhibitors ChEBI: tyrosinase inhibitors Ca(2+)-transporting ATPase inhibitor ATP phosphohydrolase (Ca(2+)-transporting) inhibitor ATP phosphohydrolase (Ca(2+)-transporting) inhibitors Any acid anhydride hydrolase inhibitor that inhibits the action of Ca(2+)-transporting ATPase (EC 3.6.3.8). CHEBI:60186 Ca(2+)-pumping ATPase inhibitor Ca(2+)-pumping ATPase inhibitors Ca(2+)-transporting ATPase inhibitors SERCA inhibitor SERCA inhibitors calcium pump inhibitor calcium pump inhibitors chebi_ontology plasma membrane Ca-ATPase inhibitor plasma membrane Ca-ATPase inhibitors sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitor sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitors sarcoplasmic reticulum ATPase inhibitor sarcoplasmic reticulum ATPase inhibitors ChEBI: calcium pump inhibitor Ca(2+)-pumping ATPase inhibitor ChEBI: Ca(2+)-pumping ATPase inhibitors ChEBI: ChEBI: sarcoplasmic reticulum ATPase inhibitor ATP phosphohydrolase (Ca(2+)-transporting) inhibitors ChEBI: ATP phosphohydrolase (Ca(2+)-transporting) inhibitor ChEBI: ChEBI: sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitor ChEBI: SERCA inhibitors ChEBI: plasma membrane Ca-ATPase inhibitors ChEBI: plasma membrane Ca-ATPase inhibitor ChEBI: sarcoplasmic reticulum ATPase inhibitors ChEBI: sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitors ChEBI: SERCA inhibitor ChEBI: calcium pump inhibitors Ca(2+)-transporting ATPase inhibitors ChEBI: mimotope Any macromolecule whose structure mimics that of an epitope. When applied to immunisation, a mimotope induces the desired antibody specificities exclusively based on the principle of molecular mimicry. CHEBI:60218 CiteXplore:17825923 CiteXplore:18228183 CiteXplore:19344285 antigenic determinant mimic chebi_ontology epitope mimic mimeotope mimeotope function mimeotope role mimetope mimotope function mimotope role ChEBI: mimotope role ChEBI: mimeotope role ChEBI: epitope mimic PubMed citation CiteXplore:17825923 ChEBI: mimetope ChEBI: mimotope function ChEBI: antigenic determinant mimic PubMed citation CiteXplore:18228183 PubMed citation CiteXplore:19344285 ChEBI: mimeotope ChEBI: mimeotope function peptidase inhibitor Any inhibitor of a peptidase. CHEBI:60258 chebi_ontology peptidase inhibitors ChEBI: peptidase inhibitors glutaminase inhibitor Any compound that inhibits the activity of a glutaminase and thus the generation of glutamate from glutamine CHEBI:60280 chebi_ontology glutaminase inhibitors ChEBI: glutaminase inhibitors thyroid hormone Any hormone produced by the thyroid gland CHEBI:60311 chebi_ontology thyroid hormones ChEBI: thyroid hormones spiroketalamine fungicide A class of fungicides whose members contain both a spiroketal moiety and an amino group. CHEBI:60545 chebi_ontology spiroketalamine fungicides ChEBI: spiroketalamine fungicides phenoxy herbicide Any member of the class of herbicides whose members contain a phenoxy or substituted phenoxy group. CHEBI:60575 chebi_ontology phenoxy herbicides ChEBI: phenoxy herbicides phenoxyacetic herbicide CHEBI:60576 Phenoxy herbicides whose members contain a (substituted) phenoxyacetic acid substructure, including salts and esters of (substituted) phenoxyacetic acid. chebi_ontology phenoxyacetic herbicides ChEBI: phenoxyacetic herbicides conazole fungicide A member of a class of fungicides that contains an imidazole or triazole moiety. CHEBI:60593 chebi_ontology conazole fungicides ChEBI: conazole fungicides opioid agent Any agent that acts on an opioid receptor or affects the life cycle of an opioid transmitter. CHEBI:60598 chebi_ontology opioid agents ChEBI: opioid agents mu-opioid agent Any agent that acts on a mu-opioid receptor. CHEBI:60599 chebi_ontology mu-opioid agents ChEBI: mu-opioid agents amide fungicide Any member of the class of fungicides which contain an amide group. CHEBI:60600 amide fungicides chebi_ontology ChEBI: amide fungicides delta-opioid agent Any agent that acts on a delta-opioid receptor. CHEBI:60601 chebi_ontology delta-opioid agents ChEBI: delta-opioid agents kappa-opioid agent Any agent that acts on a kappa-opioid receptor. CHEBI:60603 chebi_ontology kappa-opioid agents ChEBI: kappa-opioid agents opioid receptor antagonist An agent that binds to but does not activate an opioid receptor thereby blocking the actions of endogenous or exogenous opioid receptor agonists. CHEBI:60605 chebi_ontology opiate antagonist opiate antagonists opioid antagonist opioid antagonists opioid receptor antagonists ChEBI: opiate antagonists ChEBI: opiate antagonist ChEBI: opioid receptor antagonists ChEBI: opioid antagonists ChEBI: opioid antagonist opioid receptor agonist An agent that selectively binds to and activates an opioid receptor. CHEBI:60606 chebi_ontology opiate agonist opiate agonists opioid agonist opioid agonists opioid receptor agonists ChEBI: opioid agonist ChEBI: opiate agonists ChEBI: opiate agonist ChEBI: opioid receptor agonists ChEBI: opioid agonists N-methyl-D-aspartate receptor antagonist Any chemical substance that acts as an antagonist at the N-methyl-D-aspartate receptor. CHEBI:60643 N-methyl-D-aspartate receptor antagonists chebi_ontology ChEBI: N-methyl-D-aspartate receptor antagonists bridged diphenyl fungicide Any member of the class of fungicides whose members contain two phenyl (or substituted phenyl) groups attached to a single carbon or heteratom. CHEBI:60644 bridged diphenyl fungicides chebi_ontology ChEBI: bridged diphenyl fungicides chiral reagent A chiral compound used to induce stereoselectivity into a reaction. CHEBI:60646 chebi_ontology glucagon receptor antagonist An agent which blocks glucagon receptors. CHEBI:60649 chebi_ontology glucagon receptor antagonists ChEBI: glucagon receptor antagonists tryptophan synthase inhibitor Any compound that inhibits the action of tryptophan synthase. CHEBI:60688 chebi_ontology tryptophan synthase inhibitors ChEBI: tryptophan synthase inhibitors affinity label An enzyme inhibitor, generally irreversible, that is similar in structure to a particular substrate for a specific enzyme. CHEBI:60788 affinity labels chebi_ontology ChEBI: affinity labels NMDA receptor antagonist Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. CHEBI:60797 N-methyl-D-aspartate receptor antagonist N-methyl-D-aspartate receptor antagonists NMDA receptor antagonists NMDAR antagonist NMDAR antagonists chebi_ontology ChEBI: NMDAR antagonist ChEBI: N-methyl-D-aspartate receptor antagonists ChEBI: NMDAR antagonists ChEBI: NMDA receptor antagonists ChEBI: N-methyl-D-aspartate receptor antagonist excitatory amino acid antagonist Any substance which inhibits the action of receptors for excitatory amino acids. CHEBI:60798 EAA receptor antagonist EAA receptor antagonists chebi_ontology excitatory amino acid antagonists excitatory amino acid receptor antagonist excitatory amino acid receptor antagonists ChEBI: EAA receptor antagonist ChEBI: excitatory amino acid receptor antagonists ChEBI: EAA receptor antagonists ChEBI: excitatory amino acid antagonists ChEBI: excitatory amino acid receptor antagonist anaesthesia adjuvant Any substance that possesses little anaesthetic effect by itself, but which enhances or potentiates the anaesthetic action of other drugs when given at the same time. CHEBI:60807 anaesthesia adjuvants anaesthestic adjuvant anaesthestic adjuvants chebi_ontology ChEBI: anaesthesia adjuvants ChEBI: anaesthestic adjuvant ChEBI: anaesthestic adjuvants adjuvant Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself. CHEBI:60809 adjuvants chebi_ontology ChEBI: adjuvants immunogen A type of antigen capable on its own of inducing an immune response. CHEBI:60816 CiteXplore:19152635 CiteXplore:19328011 CiteXplore:19397283 chebi_ontology PubMed citation CiteXplore:19328011 PubMed citation CiteXplore:19397283 PubMed citation CiteXplore:19152635 tubulin modulator Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules. CHEBI:60832 chebi_ontology tubulin modulators ChEBI: tubulin modulators riboflavin synthetase inhibitor Any compound that inhibits the action of riboflavin synthetase. CHEBI:60901 chebi_ontology riboflavin synthase inhibitors ChEBI: riboflavin synthase inhibitors nephrotoxin A poison that interferes with the function of the kidneys. CHEBI:61015 chebi_ontology nephrotoxins ChEBI: nephrotoxins angiotensin receptor antagonist A hormone antagonist that blocks angiotensin receptors. CHEBI:61016 angiotensin receptor antagonists chebi_ontology ChEBI: angiotensin receptor antagonists bile therapy drug A drug used in the treatment of bile or liver disorders. CHEBI:61026 bile therapy agent bile therapy agents bile therapy drugs chebi_ontology ChEBI: bile therapy agents ChEBI: bile therapy agent ChEBI: bile therapy drugs histone deacetylase inhibitor An enzyme inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98). CHEBI:61115 EC 3.5.1.98 inhibitor EC 3.5.1.98 inhibitors HDAC inhibitor HDAC inhibitors HDACi HDACis HDI HDIs chebi_ontology histone amidohydrolase inhibitor histone amidohydrolase inhibitors histone deacetylase inhibitors ChEBI: EC 3.5.1.98 inhibitors ChEBI: HDACis ChEBI: HDIs ChEBI: EC 3.5.1.98 inhibitor ChEBI: HDI ChEBI: HDAC inhibitors ChEBI: histone amidohydrolase inhibitors ChEBI: histone deacetylase inhibitors ChEBI: histone amidohydrolase inhibitor ChEBI: HDAC inhibitor ChEBI: HDACi inositol phosphorylceramide synthase inhibitor An enzyme inhibitor that inhibits the action of inositol phosphorylceramide synthase. CHEBI:61774 chebi_ontology nitric oxide synthase inhibitor An enzyme inhibitor that inhibits the action of nitric oxide synthase, EC 1.14.13.39. CHEBI:61908 EC 1.14.13.39 inhibitor EC 1.14.13.39 inhibitors NADPH-diaphorase inhibitor NADPH-diaphorase inhibitors NO synthase inhibitor NO synthase inhibitors chebi_ontology endothelium-derived relaxation factor-forming enzyme inhibitor endothelium-derived relaxation factor-forming enzyme inhibitors endothelium-derived relaxing factor synthase inhibitor endothelium-derived relaxing factor synthase inhibitors nitric oxide synthase inhibitors nitric oxide synthetase inhibitor nitric oxide synthetase inhibitors nitric-oxide synthetase inhibitor nitric-oxide synthetase inhibitors ChEBI: nitric-oxide synthetase inhibitor ChEBI: nitric oxide synthetase inhibitor ChEBI: endothelium-derived relaxation factor-forming enzyme inhibitors ChEBI: endothelium-derived relaxation factor-forming enzyme inhibitor ChEBI: EC 1.14.13.39 inhibitor ChEBI: nitric-oxide synthetase inhibitors ChEBI: EC 1.14.13.39 inhibitors ChEBI: nitric oxide synthetase inhibitors ChEBI: NO synthase inhibitors ChEBI: nitric oxide synthase inhibitors ChEBI: endothelium-derived relaxing factor synthase inhibitor ChEBI: NADPH-diaphorase inhibitor ChEBI: endothelium-derived relaxing factor synthase inhibitors ChEBI: NADPH-diaphorase inhibitors ChEBI: NO synthase inhibitor microtubule-stabilising agent Any substance that interacts with tubulin to promote polymerisation of microtubules. CHEBI:61950 CiteXplore:11470606 chebi_ontology microtubule stabilising agent microtubule stabilising role microtubule stabilizing agent microtubule stabilizing agents microtubule stabilizing role microtubule-stabilising agents microtubule-stabilizing agent ChEBI: microtubule stabilising agent ChEBI: microtubule-stabilising agents ChEBI: microtubule stabilising role ChEBI: microtubule stabilizing agents PubMed citation CiteXplore:11470606 SUBMITTER: microtubule stabilizing role ChEBI: microtubule stabilizing agent ChEBI: microtubule-stabilizing agent microtubule-destabilising agent Any substance that interacts with tubulin to inhibit polymerisation of microtubules. CHEBI:61951 CiteXplore:17099073 chebi_ontology microtubule destabilising agent microtubule destabilising agents microtubule destabilising role microtubule destabilizing role microtubule-destabilising agents microtubule-destabilizing agent microtubule-destabilizing agents ChEBI: microtubule-destabilizing agent SUBMITTER: microtubule destabilizing role ChEBI: microtubule destabilising agent ChEBI: microtubule destabilising agents ChEBI: microtubule-destabilizing agents ChEBI: microtubule destabilising role ChEBI: microtubule-destabilising agents PubMed citation CiteXplore:17099073 metabotropic glutamate receptor agonist An agonist that selectively binds to and activates a metabotropic glutamate receptor. CHEBI:61966 chebi_ontology mGluRs agonist metabotropic glutamate receptor agonists ChEBI: metabotropic glutamate receptor agonists ChEBI: mGluRs agonist acyl donor Any donor that can transfer acyl groups between molecular entities. CHEBI:62049 CiteXplore:16100120 CiteXplore:19052863 chebi_ontology PubMed citation CiteXplore:16100120 PubMed citation CiteXplore:19052863 glutamate synthase inhibitor Any compound that inhibits the action of glutamate synthase. CHEBI:62089 chebi_ontology glutamate synthase inhibitors ChEBI: glutamate synthase inhibitors allelochemical A class of secondary metabolites developed by many plants to influence the behaviour, growth or survival of herbivores, and thus acting as a defence against herbivory. CHEBI:62215 allelochemicals chebi_ontology ChEBI: allelochemicals anaplastic lymphoma kinase inhibitor ALK inhibitor An enzyme inhibitor that interferes with the action of anaplastic lymphoma kinase. CHEBI:62434 chebi_ontology ALK inhibitor ChEBI: signalling molecule A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell. CHEBI:62488 chebi_ontology signal molecule signal molecules signaling molecule signaling molecules signalling molecules ChEBI: signal molecules ChEBI: signalling molecules ChEBI: signal molecule ChEBI: signaling molecule ChEBI: signaling molecules sphingosine N-acyltransferase inhibitor Any inhibitor of sphingosine N-acyltransferase, EC 2.3.1.24. CHEBI:62530 EC 2.3.1.24 inhibitor EC 2.3.1.24 inhibitors acyl-CoA:sphingosine N-acyltransferase inhibitor acyl-CoA:sphingosine N-acyltransferase inhibitors ceramide synthase inhibitor ceramide synthase inhibitors ceramide synthetase inhibitor ceramide synthetase inhibitors chebi_ontology sphingosine N-acyltransferase inhibitors sphingosine acyltransferase inhibitor sphingosine acyltransferase inhibitors ChEBI: ceramide synthetase inhibitors ChEBI: EC 2.3.1.24 inhibitor ChEBI: EC 2.3.1.24 inhibitors ChEBI: acyl-CoA:sphingosine N-acyltransferase inhibitors ChEBI: ceramide synthetase inhibitor ChEBI: ceramide synthase inhibitors ChEBI: sphingosine acyltransferase inhibitor ChEBI: sphingosine N-acyltransferase inhibitors ChEBI: ceramide synthase inhibitor ChEBI: acyl-CoA:sphingosine N-acyltransferase inhibitor ChEBI: sphingosine acyltransferase inhibitors aconitase inhibitor An enzyme inhibitor that interferes with the function of aconitase. CHEBI:62608 aconitase inhibitors chebi_ontology ChEBI: aconitase inhibitors phosphonopyruvate hydrolase inhibitor An enzyme inhibitor that interferes with the action of phosphonopyruvate hydrolase. CHEBI:62609 chebi_ontology phosphonopyruvate hydrolase inhibitors ChEBI: phosphonopyruvate hydrolase inhibitors phosphoprotein phosphatase inhibitor 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitor 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitors Any inhibitor of phosphoprotein phosphatase, EC 3.1.3.16. Aspergillus awamori acid protein phosphatase inhibitor Aspergillus awamori acid protein phosphatase inhibitors BCKDH phosphatase inhibitor BCKDH phosphatase inhibitors CHEBI:62670 EC 3.1.3.16 inhibitor EC 3.1.3.16 inhibitors HMG-CoA reductase phosphatase inhibitor HMG-CoA reductase phosphatase inhibitors branched-chain alpha-keto acid dehydrogenase phosphatase inhibitor branched-chain alpha-keto acid dehydrogenase phosphatase inhibitors calcineurin inhibitor calcineurin inhibitors casein phosphatase inhibitor casein phosphatase inhibitors chebi_ontology phosphatase 2A inhibitor phosphatase 2A inhibitors phosphatase 2B inhibitor phosphatase 2B inhibitors phosphatase C-II inhibitor phosphatase C-II inhibitors phosphatase H-II inhibitor phosphatase H-II inhibitors phosphatase I inhibitor phosphatase I inhibitors phosphatase IB inhibitor phosphatase IB inhibitors phosphatase II inhibitor phosphatase II inhibitors phosphatase III inhibitor phosphatase III inhibitors phosphatase IV inhibitor phosphatase IV inhibitors phosphatase SP inhibitor phosphatase SP inhibitors phosphoprotein phosphatase inhibitors phosphoprotein phosphohydrolase inhibitor phosphoprotein phosphohydrolase inhibitors phosphopyruvate dehydrogenase phosphatase inhibitor phosphopyruvate dehydrogenase phosphatase inhibitors phosphospectrin phosphatase inhibitor phosphospectrin phosphatase inhibitors polycation modulated (PCM-) phosphatase inhibitor polycation modulated (PCM-) phosphatase inhibitors protein D phosphatase inhibitor protein D phosphatase inhibitors protein phosphatase inhibitor protein phosphatase inhibitors protein phosphatase-1 inhibitor protein phosphatase-1 inhibitors protein phosphatase-2A inhibitor protein phosphatase-2A inhibitors protein phosphatase-2B inhibitor protein phosphatase-2B inhibitors protein phosphatase-2C inhibitor protein phosphatase-2C inhibitors 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitors ChEBI: BCKDH phosphatase inhibitor ChEBI: ChEBI: phosphatase SP inhibitors ChEBI: EC 3.1.3.16 inhibitors ChEBI: phosphatase IB inhibitors ChEBI: phosphatase II inhibitors ChEBI: phosphatase IV inhibitor ChEBI: EC 3.1.3.16 inhibitor ChEBI: phosphoprotein phosphatase inhibitors ChEBI: protein phosphatase-2A inhibitor ChEBI: protein D phosphatase inhibitor ChEBI: phosphatase C-II inhibitors ChEBI: phosphatase I inhibitors ChEBI: phosphatase SP inhibitor ChEBI: HMG-CoA reductase phosphatase inhibitor ChEBI: phosphatase I inhibitor ChEBI: protein phosphatase-2C inhibitor ChEBI: phosphatase IB inhibitor BCKDH phosphatase inhibitors ChEBI: ChEBI: phosphospectrin phosphatase inhibitor ChEBI: phosphatase II inhibitor ChEBI: phosphatase C-II inhibitor ChEBI: phosphoprotein phosphohydrolase inhibitors 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitor ChEBI: ChEBI: casein phosphatase inhibitor ChEBI: phosphospectrin phosphatase inhibitors ChEBI: calcineurin inhibitor ChEBI: polycation modulated (PCM-) phosphatase inhibitors ChEBI: phosphatase IV inhibitors ChEBI: phosphatase 2B inhibitor ChEBI: protein phosphatase-2B inhibitor ChEBI: polycation modulated (PCM-) phosphatase inhibitor ChEBI: calcineurin inhibitors ChEBI: protein phosphatase-1 inhibitor ChEBI: casein phosphatase inhibitors ChEBI: phosphoprotein phosphohydrolase inhibitor ChEBI: phosphatase III inhibitor ChEBI: protein phosphatase-2C inhibitors ChEBI: phosphopyruvate dehydrogenase phosphatase inhibitor ChEBI: protein D phosphatase inhibitors ChEBI: phosphatase 2B inhibitors Aspergillus awamori acid protein phosphatase inhibitor ChEBI: ChEBI: protein phosphatase-2A inhibitors ChEBI: phosphatase H-II inhibitors ChEBI: phosphatase III inhibitors ChEBI: protein phosphatase-1 inhibitors ChEBI: phosphopyruvate dehydrogenase phosphatase inhibitors ChEBI: protein phosphatase inhibitor ChEBI: phosphatase H-II inhibitor Aspergillus awamori acid protein phosphatase inhibitors ChEBI: ChEBI: protein phosphatase-2B inhibitors ChEBI: phosphatase 2A inhibitor ChEBI: HMG-CoA reductase phosphatase inhibitors ChEBI: protein phosphatase inhibitors ChEBI: phosphatase 2A inhibitors ChEBI: branched-chain alpha-keto acid dehydrogenase phosphatase inhibitors ChEBI: branched-chain alpha-keto acid dehydrogenase phosphatase inhibitor glycine receptor antagonist CHEBI:62754 chebi_ontology fuel additive Any additive that enhances the efficiency of fuel. CHEBI:62803 chebi_ontology fuel additives fuel enhancer ChEBI: fuel additives ChEBI: fuel enhancer hepatoprotective agent Any compound that is able to prevent damage to the liver. CHEBI:62868 antihepatotoxic agent chebi_ontology hepatoprotective agents ChEBI: hepatoprotective agents ChEBI: antihepatotoxic agent phenylalanine ammonia-lyase inhibitor CHEBI:62871 chebi_ontology retinoic acid synthase inhibitor CHEBI:62872 chebi_ontology odorant receptor agonist An agonist that selectively binds to and activates an odorant receptor. CHEBI:62873 chebi_ontology tankyrase inhibitor CHEBI:62887 chebi_ontology poly(ADP-ribose) polymerase inhibitor An enzyme inhibitor that inhibits the action of a poly(ADP-ribose)polymerase. CHEBI:62913 PARP PARPs Wikipedia:PARP_inhibitor chebi_ontology poly(ADP-ribose) polymerase inhibitors ChEBI: PARP ChEBI: PARPs ChEBI: poly(ADP-ribose) polymerase inhibitors Wikipedia Wikipedia:PARP_inhibitor axin stabilizer CHEBI:62914 chebi_ontology sialyltransferase inhibitor A compound that inhibits the action of a sialyltransferase. CHEBI:62915 chebi_ontology sialyltransferase inhibitors ChEBI: sialyltransferase inhibitors cytochrome c oxidase inhibitor An enzyme inhibitor that interferes with the action of cytochrome c oxidase. CHEBI:62966 chebi_ontology cytochrome c oxidase inhibitors ChEBI: cytochrome c oxidase inhibitors emulsifier CHEBI:63046 chebi_ontology food emulsifier An emulsifier used in food manufacturing. CHEBI:63047 chebi_ontology food emulsifiers ChEBI: food emulsifiers osteogenesis regulator CHEBI:63054 chebi_ontology phase-transfer catalyst A catalyst that facilitates the migration of a reactant from one phase into another phase where reaction occurs. CHEBI:63060 PTC Wikipedia:Phase_transfer_catalyst chebi_ontology phase transfer catalyst phase transfer catalysts phase-transfer catalysts ChEBI: phase-transfer catalysts ChEBI: phase transfer catalysts ChEBI: PTC Wikipedia Wikipedia:Phase_transfer_catalyst ChEBI: phase transfer catalyst crystallisation adjutant CHEBI:63064 Chemical role played by a material when used to promote crystallisation. Wikipedia:Crystallization_adjutant chebi_ontology crystallisation adjutants crystallization adjutant crystallization adjutants ChEBI: crystallisation adjutants Wikipedia Wikipedia:Crystallization_adjutant ChEBI: crystallization adjutant ChEBI: crystallization adjutants purine nucleoside phosphorylase inhibitor An enzyme inhibitor that interferes with the action of purine nucleoside phosphorylase. CHEBI:63090 chebi_ontology purine nucleoside phosphorylase inhibitors ChEBI: purine nucleoside phosphorylase inhibitors sphingosine-1-phosphate receptor agonist An agonist that binds to and activates sphingosine 1-phosphate receptors. CHEBI:63114 CHEBI:63172 EDG receptor agonist S1P receptor agonist S1P receptor agonists SIP agonist SIP agonists chebi_ontology sphingosine 1-phosphate receptor agonist sphingosine 1-phosphate receptor agonists sphingosine-1-phosphate receptor agonists ChEBI: sphingosine-1-phosphate receptor agonists ChEBI: S1P receptor agonists ChEBI: SIP agonist ChEBI: sphingosine 1-phosphate receptor agonist ChEBI: SIP agonists ChEBI: sphingosine 1-phosphate receptor agonists ChEBI: EDG receptor agonist ChEBI: S1P receptor agonist insulin release inhibitor Any substance that inhibits the release of insulin CHEBI:63146 chebi_ontology alcohol oxidase inhibitor An enzyme inhibitor that interferes with the action of alcohol oxidase. CHEBI:63156 alcohol oxidase inhibitors chebi_ontology ChEBI: alcohol oxidase inhibitors cystathionine-beta-synthase inhibitor An enzyme inhibitor that interferes with the action of cystathionine-beta-synthase. CHEBI:63157 chebi_ontology cystathionine-beta-synthase inhibitors ChEBI: cystathionine-beta-synthase inhibitors carnitine palmitoyltransferase-1 inhibitor An enzyme inhibitor that interferes with the action of mitochondrial carnitine palmitoyltransferase-1. CHEBI:63158 CTP-1 inhibitor chebi_ontology mitochondrial carnitine palmitoyltransferase-1 inhibitor mitochondrial carnitine palmitoyltransferase-1 inhibitors ChEBI: mitochondrial carnitine palmitoyltransferase-1 inhibitors ChEBI: mitochondrial carnitine palmitoyltransferase-1 inhibitor CTP-1 inhibitor ChEBI: T-cell proliferation inhibitor An inhibitor that interferes with the process of T-cell proliferation. CHEBI:63173 T-cell proliferation inhibitors chebi_ontology ChEBI: T-cell proliferation inhibitors peptidomimetic A small protein-like chain designed to mimic a peptide. CHEBI:63175 Wikipedia:Peptidomimetic chebi_ontology peptidomimetics ChEBI: peptidomimetics Wikipedia Wikipedia:Peptidomimetic reducing agent CHEBI:63247 The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species. Wikipedia:Reducing_agent chebi_ontology reducer reducers reducing agents reductant reductants ChEBI: reducing agents ChEBI: reductants ChEBI: reductant Wikipedia Wikipedia:Reducing_agent ChEBI: reducer ChEBI: reducers oxidising agent A substance that removes electrons from another reactant in a redox reaction. CHEBI:63248 chebi_ontology oxidant oxidants oxidiser oxidisers oxidising agents oxidizer oxidizers oxidizing agent oxidizing agents ChEBI: oxidisers ChEBI: oxidants ChEBI: oxidizers ChEBI: oxidant ChEBI: oxidizing agent ChEBI: oxidizer ChEBI: oxidiser ChEBI: oxidising agents ChEBI: oxidizing agents sodium-dependent Pi-transporter inhibitor Any substance that inhibits the action of sodium-dependent Pi-transporters. CHEBI:63330 NPC inhibitor Na-Pi inhibitor chebi_ontology sodium-dependent inorganic phosphate cotransporter inhibitor sodium-dependent inorganic phosphate transporter inhibitor ChEBI: NPC inhibitor ChEBI: sodium-dependent inorganic phosphate transporter inhibitor ChEBI: Na-Pi inhibitor ChEBI: sodium-dependent inorganic phosphate cotransporter inhibitor alkaline phosphatase inhibitor An enzyme inhibitor that interferes with the action of alkaline phosphatase. CHEBI:63332 alkaline phosphatase inhibitors chebi_ontology ChEBI: alkaline phosphatase inhibitors fibroblast growth factor receptor antagonist An antagonist at the fibroblast growth factor receptor. CHEBI:63457 FGFR inhibitor FGFR inhibitors chebi_ontology fibroblast growth factor receptor antagonists fibroblast growth factor receptor inhibitor fibroblast growth factor receptor inhibitors ChEBI: fibroblast growth factor receptor antagonists ChEBI: fibroblast growth factor receptor inhibitor ChEBI: FGFR inhibitors ChEBI: FGFR inhibitor ChEBI: fibroblast growth factor receptor inhibitors explosive A substance capable of undergoing rapid and highly exothermic decomposition. CHEBI:63490 Wikipedia:Explosive_material chebi_ontology explosive compound explosive compounds explosive material explosives explosives chemical explosives chemicals ChEBI: explosive material ChEBI: explosive compound Wikipedia Wikipedia:Explosive_material ChEBI: explosives chemical ChEBI: explosive compounds ChEBI: explosives ChEBI: explosives chemicals Na(+)/K(+)-transporting ATPase inhibitor Any acid anhydride hydrolase inhibitor that inhibits the action of Na(+)/K(+)-transporting ATPase (EC 3.6.3.9). CHEBI:63510 EC 3.6.3.9 inhibitor EC 3.6.3.9 inhibitors Na(+)/K(+)-ATPase inhibitor Na(+)/K(+)-ATPase inhibitors Na(+)/K(+)-pump inhibitor Na(+)/K(+)-pump inhibitors Na(+)/K(+)-transporting ATPase inhibitors chebi_ontology sodium pump inhibitor sodium pump inhibitors sodium-potassium adenosine triphosphatase inhibitor sodium-potassium adenosine triphosphatase inhibitors sodium-potassium pump inhibitor sodium-potassium pump inhibitors ChEBI: Na(+)/K(+)-pump inhibitor ChEBI: sodium-potassium pump inhibitors ChEBI: Na(+)/K(+)-pump inhibitors ChEBI: sodium pump inhibitors ChEBI: sodium pump inhibitor ChEBI: sodium-potassium pump inhibitor ChEBI: EC 3.6.3.9 inhibitors ChEBI: Na(+)/K(+)-ATPase inhibitors ChEBI: EC 3.6.3.9 inhibitor ChEBI: Na(+)/K(+)-ATPase inhibitor ChEBI: sodium-potassium adenosine triphosphatase inhibitors ChEBI: sodium-potassium adenosine triphosphatase inhibitor ChEBI: Na(+)/K(+)-transporting ATPase inhibitors gonadotropin releasing hormone agonist Any drug which binds to gonadotropin-releasing hormone receptors and triggers a response. CHEBI:63533 GnRH agonist GnRH agonists GnRH-A Wikipedia:Gonadotropin-releasing_hormone_agonist chebi_ontology gonadotrophin releasing hormone agonist gonadotrophin releasing hormone agonists gonadotropin releasing hormone agonists Wikipedia Wikipedia:Gonadotropin-releasing_hormone_agonist ChEBI: GnRH agonist ChEBI: gonadotrophin releasing hormone agonists ChEBI: gonadotrophin releasing hormone agonist ChEBI: gonadotropin releasing hormone agonists ChEBI: GnRH agonists ChEBI: GnRH-A glucocorticoid receptor agonist An agonist that selectively binds to and activates a glucocorticoid receptor. CHEBI:63562 chebi_ontology glucocorticoid receptor agonists ChEBI: glucocorticoid receptor agonists chemokine receptor 5 antagonist An antogonist that blocks chemokine receptor 5 (CCR5). CCR-5 antagonist CCR-5 antagonists CCR5 antagonist CCR5 antagonists CHEBI:63673 chebi_ontology chemokine receptor 5 antagonists CCR-5 antagonist ChEBI: CCR5 antagonist ChEBI: ChEBI: chemokine receptor 5 antagonists CCR5 antagonists ChEBI: CCR-5 antagonists ChEBI: 4-aminobutyrate transaminase inhibitor CHEBI:63674 chebi_ontology thymidylate synthase inhibitor Any compound that inhibits the action of thymidylate synthase. CHEBI:63720 chebi_ontology thymidylate synthase inhibitors ChEBI: thymidylate synthase inhibitors glycinamide ribonucleotide formyltransferase inhibitor Any compound that inhibits the action of glycinamide ribonucleotide formyltransferase. CHEBI:63721 chebi_ontology glycinamide ribonucleotide formyltransferase inhibitors ChEBI: glycinamide ribonucleotide formyltransferase inhibitors neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. CHEBI:63726 chebi_ontology neuroprotective agents ChEBI: neuroprotective agents retinoid X receptor agonist An agonist that selectively binds to and activates a retinoid X receptor. CHEBI:63794 Wikipedia:Retinoid_X_receptor chebi_ontology retinoid X receptor agonists ChEBI: retinoid X receptor agonists Wikipedia Wikipedia:Retinoid_X_receptor film-forming compound Any compound that leaves a pliable, cohesive, and continuous covering over a surface when applied to it. CHEBI:63908 chebi_ontology film-forming agent film-forming agents film-forming compounds ChEBI: film-forming agent ChEBI: film-forming compounds ChEBI: film-forming agents sclerotherapy agent A sclerotherapy agent is used to treat blood vessels or blood vessel malformations (vascular malformations) and also those of the lymphatic system by injection into the vessels, which makes them shrink. CHEBI:63923 chebi_ontology sclerotherapy agents ChEBI: sclerotherapy agents tyrosine 3-monooxygenase inhibitor An enzyme inhibitor that interferes with the action of tyrosine 3-monooxygenase. CHEBI:63932 chebi_ontology tyrosine 3-monooxygenase inhibitors tyrosine hydroxylase inhibitor tyrosine hydroxylase inhibitors ChEBI: tyrosine hydroxylase inhibitors ChEBI: tyrosine 3-monooxygenase inhibitors ChEBI: tyrosine hydroxylase inhibitor alpha1B-adrenoceptor antagonist An antagonist at the alpha1B-adrenoceptor. CHEBI:63936 alpha1B-adrenoceptor antagonists chebi_ontology ChEBI: alpha1B-adrenoceptor antagonists estrogen receptor agonist An agonist at the estrogen receptor. CHEBI:63951 chebi_ontology estrogen receptor agonists ChEBI: estrogen receptor agonists adenosine A1 receptor antagonist An antagonist at the A1 receptor. CHEBI:63957 Wikipedia:Adenosine_A1_receptor adenosine A1 receptor antagonists chebi_ontology ChEBI: adenosine A1 receptor antagonists Wikipedia Wikipedia:Adenosine_A1_receptor cellulose synthesis inhibitor An enzyme inhibitor that inhibits the synthesis of cellulose. CHEBI:63958 cellulose synthesis inhibitors chebi_ontology ChEBI: cellulose synthesis inhibitors Hsp90 inhibitor An inhibitor that blocks the action of heat shock protein 90. CHEBI:63962 CiteXplore:19860732 CiteXplore:19946660 CiteXplore:22035754 CiteXplore:22920907 CiteXplore:22959035 CiteXplore:23160336 CiteXplore:23312026 Hsp90 inhibitors Wikipedia:Hsp90_inhibitors chebi_ontology heat shock protein 90 inhibitor heat shock protein 90 inhibitors PubMed citation CiteXplore:23160336 PubMed citation CiteXplore:22035754 ChEBI: heat shock protein 90 inhibitor PubMed citation CiteXplore:22959035 PubMed citation CiteXplore:19946660 Wikipedia Wikipedia:Hsp90_inhibitors ChEBI: Hsp90 inhibitors PubMed citation CiteXplore:19860732 ChEBI: heat shock protein 90 inhibitors PubMed citation CiteXplore:23312026 PubMed citation CiteXplore:22920907 metabotropic glutamate receptor antagonist An antagonist at the metabotropic glutamate receptor. CHEBI:63963 chebi_ontology mGluR antagonist mGluR antagonists metabotropic glutamate receptor antagonists ChEBI: mGluR antagonists ChEBI: mGluR antagonist ChEBI: metabotropic glutamate receptor antagonists protein kinase C agonist An agonist that selectively binds to and activates a protein kinase C receptor CHEBI:64018 chebi_ontology protein kinase C agonists ChEBI: protein kinase C agonists arachidonoylethanolamide amidohydrolase inhibitor An enzyme inhibitor that interferes with the action of arachidonoylethanolamide amidohydrolase. CHEBI:64033 arachidonoylethanolamide amidohydrolase inhibitors chebi_ontology ChEBI: arachidonoylethanolamide amidohydrolase inhibitors food additive Any substance which is added to food to preserve or enhance its flavour and/or appearance. CHEBI:64047 Wikipedia:Food_additive chebi_ontology food additives Wikipedia Wikipedia:Food_additive ChEBI: food additives acidity regulator A food additive that is used to change or otherwise control the acidity and alkalinity of foods. They may be acids, bases, neutralising agents or bufffering agents. CHEBI:64049 Wikipedia:Acidity_regulator acidity regulators chebi_ontology pH control agent pH control agents ChEBI: pH control agent ChEBI: acidity regulators Wikipedia Wikipedia:Acidity_regulator ChEBI: pH control agents delta-opioid receptor agonist CHEBI:64054 chebi_ontology incretin mimetic Any compound that mimics the action of incretins, gastrointestinal hormones that cause an increase in the amount of insulin released from the beta cells of the islets of Langerhans after eating, even before blood glucose levels become elevated. CHEBI:64088 chebi_ontology incretin mimetics ChEBI: incretin mimetics AMPA receptor agonist AMPA receptor agonists AMPAR agonist An agonist that selectively binds to and activates AMPA receptors. CHEBI:64102 Wikipedia:AMPA_receptor alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor agonist chebi_ontology quisqualate receptor agonist ChEBI: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor agonist ChEBI: quisqualate receptor agonist AMPA receptor agonists ChEBI: Wikipedia Wikipedia:AMPA_receptor AMPAR agonist ChEBI: protein kinase G agonist An agonist that selectively binds to and activates a protein kinase G receptor. CHEBI:64105 chebi_ontology protein kinase G agonists ChEBI: protein kinase G agonists protein kinase agonist An agonist that selectively binds to and activates a protein kinase receptor. CHEBI:64106 chebi_ontology protein kinase agonists ChEBI: protein kinase agonists protein farnesyltransferase inhibitor CHEBI:64133 Enzyme inhibitor of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group. chebi_ontology farnesyl transferase inhibitor farnesyl transferase inhibitors farnesyltransferase inhibitor farnesyltransferase inhibitors protein farnesyltransferase inhibitors ChEBI: farnesyltransferase inhibitor ChEBI: farnesyl transferase inhibitors ChEBI: protein farnesyltransferase inhibitors ChEBI: farnesyl transferase inhibitor ChEBI: farnesyltransferase inhibitors cysteine protease inhibitor Any protease inhibitor that restricts the action of a cysteine protease. CHEBI:64152 chebi_ontology cysteine protease inhibitors cysteine proteinase inhibitor cysteine proteinase inhibitors ChEBI: cysteine proteinase inhibitors ChEBI: cysteine protease inhibitors ChEBI: cysteine proteinase inhibitor H3-receptor agonist A histamine agonist that binds to and activates histamine H3-receptors. CHEBI:64154 H3-receptor agonists chebi_ontology histamine H3-receptor agonist histamine H3-receptor agonists ChEBI: histamine H3-receptor agonist ChEBI: H3-receptor agonists ChEBI: histamine H3-receptor agonists H4-receptor agonist A histamine agonist that binds to and activates H4-receptors. CHEBI:64155 H4-receptor agonists chebi_ontology ChEBI: H4-receptor agonists H3-receptor antagonist A histamine antagonist that selectively binds to but does not activate histamine H3 receptors, thereby blocking the actions of endogenous histamine. CHEBI:64176 H3-receptor antagonists chebi_ontology histamine H3-receptor antagonist histamine H3-receptor antagonists ChEBI: histamine H3-receptor antagonists ChEBI: H3-receptor antagonists ChEBI: histamine H3-receptor antagonist N-acetylglucosamine phosphotransferase inhibitor An enzyme inhibitor that inhibits any of the bacterial and eukaryote phosphotransferases, preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins. CHEBI:64237 N-acetylglucosamine transferase inhibitors chebi_ontology ChEBI: N-acetylglucosamine transferase inhibitors reaction intermediate Any chemical substance produced during the conversion of a reactant to a product. CHEBI:64297 Wikipedia:Reaction intermediate chebi_ontology chemical intermediate ChEBI: chemical intermediate Wikipedia Wikipedia:Reaction intermediate K-ATP channel agonist A compound which acts as an agonist at the ATP-sensitive K+ channel. ATP-sensitive K(+) channel agonist ATP-sensitive K(+) channel agonists ATP-sensitive K+ channel agonist ATP-sensitive K+ channel agonists ATP-sensitive K+ channel opener ATP-sensitive K+ channel openers CHEBI:64338 K(ATP) channel agonist K(ATP) channel agonists K-ATP channel agonists chebi_ontology ATP-sensitive K(+) channel agonist ChEBI: ChEBI: K(ATP) channel agonist ATP-sensitive K(+) channel agonists ChEBI: ATP-sensitive K+ channel agonist ChEBI: ATP-sensitive K+ channel openers ChEBI: ATP-sensitive K+ channel opener ChEBI: ATP-sensitive K+ channel agonists ChEBI: ChEBI: K(ATP) channel agonists ChEBI: K-ATP channel agonists MALDI matrix material 'matrix-assisted laser desorption/ionization' matrix material 'matrix-assisted laser desorption/ionization' matrix materials A compound used to form the matrix for MALDI (matrix-assisted laser desorption/ionization) mass spectrometry. MALDI matrix materials are crystalline compounds with a fairly low molecular weight, so as to allow facile vaporization, have strong absorption at UV or IR wavelengths (to rapidly and efficiently absorb laser irradiation), generally contain polar groups (enabling them to be used in aqueous solutions) and are frequently acidic (so assisting ionisation of the compound being studied, which is contained within the matrix material). CHEBI:64345 CiteXplore:15373456 MALDI matrix materials MALDI matrix solution MALDI matrix solutions Patent:EP2060919 Wikipedia:Matrix-assisted_laser_desorption/ionization#Matrix chebi_ontology ChEBI: MALDI matrix solutions Wikipedia Wikipedia:Matrix-assisted_laser_desorption/ionization#Matrix ChEBI: MALDI matrix materials PubMed citation CiteXplore:15373456 'matrix-assisted laser desorption/ionization' matrix materials ChEBI: 'matrix-assisted laser desorption/ionization' matrix material ChEBI: ChEBI: MALDI matrix solution Patent Patent:EP2060919 glutamate transporter activator A neurotransmitter transporter modulator that activates glutamate transporters. CHEBI:64370 chebi_ontology excitatory amino-acid transporter activator excitatory amino-acid transporter activators glutamate transporter activators ChEBI: glutamate transporter activators ChEBI: excitatory amino-acid transporter activators ChEBI: excitatory amino-acid transporter activator neurotransmitter transporter modulator A membrane transport modulator that affects the transport of neurotransmitters. CHEBI:64371 chebi_ontology neurotransmitter transporter modulators ChEBI: neurotransmitter transporter modulators cathepsin K inhibitor A cysteine protease inhibitor which inhibits cathepsin K (EC 3.4.22.38). CHEBI:64406 EC 3.4.22.38 inhibitor EC 3.4.22.38 inhibitors Wikipedia:Cathepsin_K cathepsin K inhibitors cathepsin O2 inhibitor cathepsin O2 inhibitors chebi_ontology Wikipedia Wikipedia:Cathepsin_K ChEBI: cathepsin K inhibitors ChEBI: cathepsin O2 inhibitors ChEBI: EC 3.4.22.38 inhibitors ChEBI: cathepsin O2 inhibitor ChEBI: EC 3.4.22.38 inhibitor geranylgeranyl diphosphate synthase inhibitor An enzyme inhibitor that inhibits the action of geranylgeranyl diphosphate synthase (EC 2.5.1.29). CHEBI:64411 EC 2.5.1.29 inhibitor EC 2.5.1.29 inhibitors GGPP synthase inhibitor GGPP synthase inhibitors Patent:EP1280891 Patent:US2002004218 chebi_ontology geranylgeranyl diphosphate synthase inhibitors ChEBI: EC 2.5.1.29 inhibitor ChEBI: GGPP synthase inhibitors ChEBI: GGPP synthase inhibitor ChEBI: geranylgeranyl diphosphate synthase inhibitors ChEBI: EC 2.5.1.29 inhibitors Patent Patent:US2002004218 Patent Patent:EP1280891 arogenate dehydrogenase inhibitor An enzyme inhibitor that interferes with the action of arogenate dehydrogenase (EC 1.3.1.43). CHEBI:64416 EC 1.3.1.43 inhibitor EC 1.3.1.43 inhibitors L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitor L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitors L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitor L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitors L-arogenate:NAD+ oxidoreductase inhibitor L-arogenate:NAD+ oxidoreductase inhibitors TyrA(a) inhibitor TyrA(a) inhibitors Wikipedia:Arogenate_dehydrogenase arogenate dehydrogenase inhibitors chebi_ontology cyclohexadienyl dehydrogenase inhibitor cyclohexadienyl dehydrogenase inhibitors ChEBI: TyrA(a) inhibitors ChEBI: L-arogenate:NAD+ oxidoreductase inhibitor ChEBI: L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitor ChEBI: L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitor Wikipedia Wikipedia:Arogenate_dehydrogenase ChEBI: arogenate dehydrogenase inhibitors ChEBI: TyrA(a) inhibitor ChEBI: cyclohexadienyl dehydrogenase inhibitors ChEBI: EC 1.3.1.43 inhibitors ChEBI: cyclohexadienyl dehydrogenase inhibitor ChEBI: L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitors ChEBI: EC 1.3.1.43 inhibitor ChEBI: L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitors ChEBI: L-arogenate:NAD+ oxidoreductase inhibitors monolignol A secondary metabolite of plant origin (phytochemical) which acting as a source material for biosynthesis of both lignans and lignin. CHEBI:64477 Wikipedia:Monolignol chebi_ontology monolignols Wikipedia Wikipedia:Monolignol ChEBI: monolignols serine hydroxymethyltransferase inhibitor An enzyme inhibitor that interferes with the action of serine hydroxymethyltransferase. CHEBI:64570 chebi_ontology serine hydroxymethyltransferase inhibitors ChEBI: serine hydroxymethyltransferase inhibitors NMDA receptor agonist An excitatory amino acid agonist which binds to NMDA receptors and triggers a response. CHEBI:64571 N-methyl-D-aspartate receptor agonist N-methyl-D-aspartate receptor agonists NMDA receptor agonists NMDAR agonist NMDAR agonists chebi_ontology ChEBI: N-methyl-D-aspartate receptor agonist ChEBI: NMDAR agonists ChEBI: N-methyl-D-aspartate receptor agonists ChEBI: NMDAR agonist ChEBI: NMDA receptor agonists flour treatment agent A food additive which is added to flour to improve baking functionality. They include bleaching agents, oxidising agents and reducing agents. CHEBI:64577 Wikipedia:Flour_treatment_agent chebi_ontology dough improver dough improvers flour treatment agent improving agent improving agents ChEBI: dough improver ChEBI: dough improvers ChEBI: improving agent ChEBI: improving agents Wikipedia Wikipedia:Flour_treatment_agent ChEBI: flour treatment agent uremic toxin A toxin that accumulates in patients with chronic kidney disease. CHEBI:64584 Wikipedia:Uremic_toxin chebi_ontology uremic toxins ChEBI: uremic toxins Wikipedia Wikipedia:Uremic_toxin glycine transporter 1 inhibitor Any substance that inhibits the action of glycine 1 transporters. CHEBI:64588 CiteXplore:17504107 CiteXplore:18758757 CiteXplore:20678516 CiteXplore:21141920 CiteXplore:21531289 CiteXplore:22177408 Wikipedia:Glycine_transporter_1 chebi_ontology glycine transporter 1 inhibitors glycine transporter inhibitor glycine transporter inhibitors PubMed citation CiteXplore:21531289 PubMed citation CiteXplore:21141920 PubMed citation CiteXplore:20678516 ChEBI: glycine transporter 1 inhibitors PubMed citation CiteXplore:22177408 ChEBI: glycine transporter inhibitor PubMed citation CiteXplore:17504107 ChEBI: glycine transporter inhibitors PubMed citation CiteXplore:18758757 Wikipedia Wikipedia:Glycine_transporter_1 glycine receptor agonist An agonist that binds to and activates glycine receptors CHEBI:64589 chebi_ontology glycine receptor agonists ChEBI: glycine receptor agonists thioredoxin reductase inhibitor An enzyme inhibitor that inhibits thioredoxin reductase (EC 1.8.1.9) CHEBI:64670 EC 1.8.1.9 inhibitor EC 1.8.1.9 inhibitors NADP-thioredoxin reductase inhibitor NADP-thioredoxin reductase inhibitors NADPH-thioredoxin reductase inhibitor NADPH-thioredoxin reductase inhibitors NADPH2:oxidized thioredoxin oxidoreductase inhibitor NADPH2:oxidized thioredoxin oxidoreductase inhibitors TrxR inhibitor TrxR inhibitors Wikipedia:Thioredoxin_reductase chebi_ontology thioredoxin reductase (NADPH) inhibitor thioredoxin reductase (NADPH) inhibitors thioredoxin reductase inhibitors thioredoxin-disulfide reductase inhibitor thioredoxin-disulfide reductase inhibitors thioredoxin:NADP+ oxidoreductase inhibitor thioredoxin:NADP+ oxidoreductase inhibitors ChEBI: TrxR inhibitor ChEBI: NADPH-thioredoxin reductase inhibitor ChEBI: NADPH2:oxidized thioredoxin oxidoreductase inhibitors ChEBI: NADP-thioredoxin reductase inhibitor ChEBI: thioredoxin:NADP+ oxidoreductase inhibitor ChEBI: NADPH-thioredoxin reductase inhibitors Wikipedia Wikipedia:Thioredoxin_reductase ChEBI: EC 1.8.1.9 inhibitors ChEBI: thioredoxin-disulfide reductase inhibitors ChEBI: NADPH2:oxidized thioredoxin oxidoreductase inhibitor ChEBI: NADP-thioredoxin reductase inhibitors ChEBI: TrxR inhibitors ChEBI: thioredoxin-disulfide reductase inhibitor ChEBI: EC 1.8.1.9 inhibitor ChEBI: thioredoxin reductase (NADPH) inhibitor ChEBI: thioredoxin reductase (NADPH) inhibitors ChEBI: thioredoxin:NADP+ oxidoreductase inhibitors ChEBI: thioredoxin reductase inhibitors acyl-CoA:cholesterol acyltransferase inhibitor ACAT inhibitor ACAT inhibitors An enzyme inhibitor that interferes with the action of acyl-CoA:cholesterol acyltransferase. CHEBI:64696 acyl-CoA:cholesterol acyltransferase inhibitors chebi_ontology ACAT inhibitor ChEBI: ChEBI: acyl-CoA:cholesterol acyltransferase inhibitors ACAT inhibitors ChEBI: acyl-CoA:cholesterol acyltransferase 2 inhibitor ACAT-2 inhibitor ACAT-2 inhibitors An acyl-CoA:cholesterol acyltransferase inhibitor that specifically inhibits acyl-CoA:cholesterol acyltransferase 2. CHEBI:64697 acyl-CoA:cholesterol acyltransferase 2 inhibitors chebi_ontology ACAT-2 inhibitor ChEBI: ACAT-2 inhibitors ChEBI: ChEBI: acyl-CoA:cholesterol acyltransferase 2 inhibitors phosphatidylinositol-specific phospholipase C inhibitor An enzyme inhibitor that interferes with the action of phosphatidylinositol-specific phospholipase C. CHEBI:64763 PI-PLC inhibitor PI-PLC inhibitors Wikipedia:Phosphatidylinositol-specific_phospholipase_C chebi_ontology phosphatidylinositol-specific phospholipase C inhibitors ChEBI: PI-PLC inhibitors Wikipedia Wikipedia:Phosphatidylinositol-specific_phospholipase_C ChEBI: PI-PLC inhibitor ChEBI: phosphatidylinositol-specific phospholipase C inhibitors cosmetic CHEBI:64857 The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it. Wikipedia:Cosmetics chebi_ontology cosmetic component cosmetics ChEBI: cosmetic component ChEBI: cosmetics Wikipedia Wikipedia:Cosmetics poison Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism. CHEBI:64909 Wikipedia:Poison chebi_ontology poisonous agent poisonous agents poisonous substance poisonous substances poisons toxic agent toxic agents toxic substance toxic substances ChEBI: poisonous agents ChEBI: poisonous agent ChEBI: toxic substance ChEBI: toxic substances ChEBI: poisons Wikipedia Wikipedia:Poison ChEBI: toxic agents ChEBI: toxic agent ChEBI: poisonous substances ChEBI: poisonous substance antimitotic Any compound that inhibits cell division (mitosis). CHEBI:64911 Wikipedia:Mitotic_inhibitor antimitotics chebi_ontology mitosis inhibitor mitosis inhibitors mitotic inhibitor mitotic inhibitors ChEBI: mitosis inhibitors ChEBI: mitosis inhibitor ChEBI: antimitotics ChEBI: mitotic inhibitors ChEBI: mitotic inhibitor Wikipedia Wikipedia:Mitotic_inhibitor antimycobacterial drug A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy. CHEBI:64912 antimycobacterial agent antimycobacterial agents antimycobacterial drugs antimycobacterials antimycobacterium chebi_ontology ChEBI: antimycobacterium ChEBI: antimycobacterial drugs ChEBI: antimycobacterials ChEBI: antimycobacterial agent ChEBI: antimycobacterial agents antiplasmodial drug An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria. CHEBI:64915 antiplasmodial agent antiplasmodial agents antiplasmodial drugs antiplasmodium agent antiplasmodium agents antiplasmodium drug antiplasmodium drugs chebi_ontology ChEBI: antiplasmodial agents ChEBI: antiplasmodium agent ChEBI: antiplasmodium agents ChEBI: antiplasmodium drugs ChEBI: antiplasmodium drug ChEBI: antiplasmodial drugs ChEBI: antiplasmodial agent diacylglycerol O-acyltransferase inhibitor 1,2-diacylglycerol acyltransferase inhibitor 1,2-diacylglycerol acyltransferase inhibitors An enzyme inhibitor that inhibits diacylglycerol O-acyltransferase (EC 2.3.1.20). CHEBI:64919 DGAT inhibitor DGAT inhibitors EC 2.3.1.20 inhibitor EC 2.3.1.20 inhibitors Wikipedia:Dgat acyl-CoA:1,2-diacylglycerol O-acyltransferase inhibitor acyl-CoA:1,2-diacylglycerol O-acyltransferase inhibitors chebi_ontology diacylglycerol O-acyltransferase inhibitors diacylglycerol acyltransferase inhibitor diacylglycerol acyltransferase inhibitors diglyceride O-acyltransferase inhibitor diglyceride O-acyltransferase inhibitors diglyceride acyltransferase inhibitor diglyceride acyltransferase inhibitors palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase inhibitor palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase inhibitors ChEBI: diglyceride O-acyltransferase inhibitor 1,2-diacylglycerol acyltransferase inhibitors ChEBI: ChEBI: DGAT inhibitors ChEBI: diglyceride acyltransferase inhibitors Wikipedia Wikipedia:Dgat ChEBI: EC 2.3.1.20 inhibitors ChEBI: DGAT inhibitor ChEBI: diacylglycerol acyltransferase inhibitors ChEBI: acyl-CoA:1,2-diacylglycerol O-acyltransferase inhibitors ChEBI: diacylglycerol acyltransferase inhibitor ChEBI: diglyceride O-acyltransferase inhibitors ChEBI: palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase inhibitors ChEBI: diglyceride acyltransferase inhibitor ChEBI: acyl-CoA:1,2-diacylglycerol O-acyltransferase inhibitor ChEBI: palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase inhibitor ChEBI: diacylglycerol O-acyltransferase inhibitors 1,2-diacylglycerol acyltransferase inhibitor ChEBI: ChEBI: EC 2.3.1.20 inhibitor DNA ligase (ATP) inhibitor A phosphoric ester bond-forming ligase inhibitor that inhibits the action of DNA ligase (ATP), EC 6.5.1.1. CHEBI:64920 DNA joinase inhibitor DNA joinase inhibitors DNA ligase inhibitor DNA ligase inhibitors DNA repair enzyme inhibitor DNA repair enzyme inhibitors DNA-joining enzyme inhibitor DNA-joining enzyme inhibitors EC 6.5.1.1 inhibitor EC 6.5.1.1 inhibitors Wikipedia:Dna_Ligase chebi_ontology deoxyribonucleate ligase inhibitor deoxyribonucleate ligase inhibitors deoxyribonucleic acid joinase inhibitor deoxyribonucleic acid joinase inhibitors deoxyribonucleic acid ligase inhibitor deoxyribonucleic acid ligase inhibitors deoxyribonucleic acid repair enzyme inhibitor deoxyribonucleic acid repair enzyme inhibitors deoxyribonucleic acid-joining enzyme inhibitor deoxyribonucleic acid-joining enzyme inhibitors deoxyribonucleic joinase inhibitor deoxyribonucleic joinase inhibitors deoxyribonucleic ligase inhibitor deoxyribonucleic ligase inhibitors deoxyribonucleic repair enzyme inhibitor deoxyribonucleic repair enzyme inhibitors deoxyribonucleic-joining enzyme inhibitor deoxyribonucleic-joining enzyme inhibitors polydeoxyribonucleotide synthase (ATP) inhibitor sealase inhibitor sealase inhibitors ChEBI: deoxyribonucleic ligase inhibitors ChEBI: sealase inhibitor ChEBI: deoxyribonucleic acid ligase inhibitors ChEBI: deoxyribonucleic acid joinase inhibitor ChEBI: deoxyribonucleic-joining enzyme inhibitors ChEBI: sealase inhibitors ChEBI: DNA joinase inhibitors ChEBI: DNA repair enzyme inhibitors ChEBI: deoxyribonucleic acid repair enzyme inhibitor ChEBI: deoxyribonucleic acid repair enzyme inhibitors ChEBI: deoxyribonucleic acid ligase inhibitor ChEBI: DNA ligase inhibitor ChEBI: deoxyribonucleic acid-joining enzyme inhibitor ChEBI: DNA joinase inhibitor ChEBI: deoxyribonucleic acid-joining enzyme inhibitors ChEBI: polydeoxyribonucleotide synthase (ATP) inhibitor ChEBI: deoxyribonucleic joinase inhibitors ChEBI: deoxyribonucleate ligase inhibitors ChEBI: deoxyribonucleic ligase inhibitor ChEBI: DNA-joining enzyme inhibitor ChEBI: deoxyribonucleic repair enzyme inhibitor ChEBI: deoxyribonucleic-joining enzyme inhibitor ChEBI: EC 6.5.1.1 inhibitor ChEBI: EC 6.5.1.1 inhibitors ChEBI: DNA-joining enzyme inhibitors ChEBI: DNA ligase inhibitors ChEBI: deoxyribonucleic joinase inhibitor ChEBI: DNA repair enzyme inhibitor ChEBI: deoxyribonucleic repair enzyme inhibitors ChEBI: deoxyribonucleic acid joinase inhibitors ChEBI: deoxyribonucleate ligase inhibitor Wikipedia Wikipedia:Dna_Ligase leukocyte elastase inhibitor An enzyme inhibitor that inhibits leukocyte elastase, EC 6.5.1.1. CHEBI:64922 EC 3.4.21.37 inhibitor EC 3.4.21.37 inhibitors chebi_ontology elastase inhibitor elastase inhibitors elaszym inhibitor elaszym inhibitors granulocyte elastase inhibitor granulocyte elastase inhibitors lysosomal elastase inhibitor lysosomal elastase inhibitors neutrophil elastase inhibitor neutrophil elastase inhibitors polymorphonuclear leukocyte elastase inhibitor polymorphonuclear leukocyte elastase inhibitors serine elastase inhibitor serine elastase inhibitors ChEBI: neutrophil elastase inhibitors ChEBI: elaszym inhibitor ChEBI: polymorphonuclear leukocyte elastase inhibitor ChEBI: neutrophil elastase inhibitor ChEBI: elaszym inhibitors ChEBI: EC 3.4.21.37 inhibitors ChEBI: granulocyte elastase inhibitor ChEBI: serine elastase inhibitor ChEBI: lysosomal elastase inhibitors ChEBI: polymorphonuclear leukocyte elastase inhibitors ChEBI: elastase inhibitor ChEBI: EC 3.4.21.37 inhibitor ChEBI: serine elastase inhibitors ChEBI: lysosomal elastase inhibitor ChEBI: elastase inhibitors ChEBI: granulocyte elastase inhibitors hepatitis C protease inhibitor An inhibitor of hepatitis C protease, an enzyme required for production of proteins needed for viral assembly. CHEBI:64924 chebi_ontology hepatitis C protease inhibitors ChEBI: hepatitis C protease inhibitors serine protease inhibitor Any protease inhibitor that restricts the action of a serine protease. CHEBI:64926 chebi_ontology serine protease inhibitors serine proteinase inhibitor serine proteinase inhibitors ChEBI: serine proteinase inhibitor ChEBI: serine protease inhibitors ChEBI: serine proteinase inhibitors cathepsin B inhibitor A cysteine protease inhibitor which inhibits cathepsin B (EC 3.4.22.1). CHEBI:64932 EC 3.4.22.1 inhibitor EC 3.4.22.1 inhibitors cathepsin B inhibitors cathepsin B1 inhibitor cathepsin B1 inhibitors cathepsin II inhibitor cathepsin II inhibitors chebi_ontology ChEBI: cathepsin B inhibitors ChEBI: cathepsin II inhibitors ChEBI: EC 3.4.22.1 inhibitors ChEBI: cathepsin B1 inhibitors ChEBI: cathepsin B1 inhibitor ChEBI: EC 3.4.22.1 inhibitor ChEBI: cathepsin II inhibitor melanin synthesis inhibitor A depigmentation agent which inhibits the synthesis of melanin. CHEBI:64933 chebi_ontology melanin synthesis inhibitors melanogenesis inhibitor melanogenesis inhibitors ChEBI: melanin synthesis inhibitors ChEBI: melanogenesis inhibitor ChEBI: melanogenesis inhibitors chymotrypsin inhibitor An enzyme inhibitor that inhibits the action of chymotrypsin (EC 3.4.21.1). CHEBI:64943 EC 3.4.21.1 inhibitor EC 3.4.21.1 inhibitors alpha-chymotrypsin inhibitor alpha-chymotrypsin inhibitors chebi_ontology chymotrypsin inhibitors chymotrypsins A inhibitor chymotrypsins A inhibitors chymotrypsins B inhibitor chymotrypsins B inhibitors ChEBI: chymotrypsins A inhibitor ChEBI: chymotrypsin inhibitors ChEBI: chymotrypsins B inhibitors ChEBI: alpha-chymotrypsin inhibitors ChEBI: alpha-chymotrypsin inhibitor ChEBI: EC 3.4.21.1 inhibitor ChEBI: chymotrypsins B inhibitor ChEBI: chymotrypsins A inhibitors ChEBI: EC 3.4.21.1 inhibitors anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. CHEBI:64946 anti-AIDS agent anti-AIDS agents anti-HIV agents chebi_ontology ChEBI: anti-HIV agents ChEBI: anti-AIDS agent ChEBI: anti-AIDS agents anti-HIV-1 agent An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus. CHEBI:64947 anti-HIV-1 agents anti-HTLV-III agent anti-HTLV-III agents anti-LAV agent anti-LAV agents chebi_ontology ChEBI: anti-HTLV-III agents ChEBI: anti-HTLV-III agent ChEBI: anti-LAV agent ChEBI: anti-HIV-1 agents ChEBI: anti-LAV agents anti-HIV-2 agent An anti-HIV agent that destroys or inhibits the replication of HIV-2, the less infective and less virulent of the two types of HIV virus. CHEBI:64949 anti-HIV-2 agents chebi_ontology ChEBI: anti-HIV-2 agents anti-HBV agent An antiviral agent that destroys or inhibits the replication of the hepatitis B virus. CHEBI:64951 CiteXplore:20712567 anti-HBV agents anti-hepatitis B virus agent anti-hepatitis B virus agents chebi_ontology PubMed citation CiteXplore:20712567 ChEBI: anti-hepatitis B virus agent ChEBI: anti-hepatitis B virus agents ChEBI: anti-HBV agents anti-HSV agent An antiviral agent that destroys or inhibits the replication of the herpes simplex virus (also known as the human herpes virus). CHEBI:64952 Wikipedia:Herpes simplex virus anti-HHV agent anti-HHV agents anti-HSV agents anti-herpes simplex virus agent anti-herpes simplex virus agents anti-human herpes virus agent anti-human herpes virus agents chebi_ontology ChEBI: anti-HSV agents ChEBI: anti-herpes simplex virus agents ChEBI: anti-HHV agent Wikipedia Wikipedia:Herpes simplex virus ChEBI: anti-human herpes virus agent ChEBI: anti-human herpes virus agents ChEBI: anti-HHV agents ChEBI: anti-herpes simplex virus agent anti-HSV-1 agent An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-1. CHEBI:64953 anti-HHV-1 agent anti-HHV-1 agents anti-HHV-I agent anti-HHV-I agents anti-HSV-1 agents anti-HSV-I agent anti-HSV-I agents anti-human herpes virus-1 agent anti-human herpes virus-1 agents anti-human herpes virus-I agent anti-human herpes virus-I agents chebi_ontology ChEBI: anti-HHV-1 agent ChEBI: anti-HHV-1 agents ChEBI: anti-human herpes virus-I agent ChEBI: anti-human herpes virus-I agents ChEBI: anti-human herpes virus-1 agents ChEBI: anti-HHV-I agents ChEBI: anti-HSV-1 agents ChEBI: anti-HSV-I agents ChEBI: anti-HSV-I agent ChEBI: anti-human herpes virus-1 agent ChEBI: anti-HHV-I agent anti-HSV-2 agent An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-2. CHEBI:64954 anti-HHV-2 agent anti-HHV-2 agents anti-HHV-II agent anti-HHV-II agents anti-HSV-2 agents anti-HSV-II agent anti-HSV-II agents anti-human herpes virus-2 agent anti-human herpes virus-2 agents anti-human herpes virus-II agent anti-human herpes virus-II agents chebi_ontology ChEBI: anti-HHV-2 agent ChEBI: anti-HSV-II agents ChEBI: anti-HSV-II agent ChEBI: anti-HHV-II agents ChEBI: anti-HHV-2 agents ChEBI: anti-human herpes virus-2 agent ChEBI: anti-HSV-2 agents ChEBI: anti-human herpes virus-II agents ChEBI: anti-human herpes virus-II agent ChEBI: anti-HHV-II agent ChEBI: anti-human herpes virus-2 agents heparanase inhibitor An enzyme inhibitor that interferes with the action of heparanase, EC 3.2.1.166. C1A heparanase inhibitor C1A heparanase inhibitors CHEBI:64955 HPSE inhibitor HPSE inhibitors Hpa1 heparanase inhibitor Hpa1 heparanase inhibitors Hpa1 inhibitor Hpa1 inhibitors chebi_ontology heparan sulfate N-sulfo-D-glucosamine endoglucanase inhibitor heparan sulfate N-sulfo-D-glucosamine endoglucanase inhibitors heparanase 1 inhibitor heparanase 1 inhibitors heparanase inhibitors heparanase-1 inhibitor heparanase-1 inhibitors C1A heparanase inhibitors ChEBI: ChEBI: heparanase inhibitors ChEBI: heparan sulfate N-sulfo-D-glucosamine endoglucanase inhibitor ChEBI: heparan sulfate N-sulfo-D-glucosamine endoglucanase inhibitors ChEBI: HPSE inhibitor ChEBI: heparanase-1 inhibitors ChEBI: heparanase 1 inhibitor C1A heparanase inhibitor ChEBI: ChEBI: Hpa1 inhibitor ChEBI: Hpa1 inhibitors ChEBI: Hpa1 heparanase inhibitors ChEBI: HPSE inhibitors ChEBI: Hpa1 heparanase inhibitor ChEBI: heparanase 1 inhibitors ChEBI: heparanase-1 inhibitor chymase inhibitor A protease inhibitor that interferes with the action of chymase (EC 3.4.21.39). CHEBI:64957 EC 3.4.21.39 inhibitor EC 3.4.21.39 inhibitors SK protease inhibitor SK protease inhibitors chebi_ontology chymase inhibitors mast cell protease I inhibitor mast cell protease I inhibitors skeletal muscle (SK) protease inhibitor skeletal muscle (SK) protease inhibitors skeletal muscle protease inhibitor skeletal muscle protease inhibitors skin chymotryptic proteinase inhibitor skin chymotryptic proteinase inhibitors ChEBI: skin chymotryptic proteinase inhibitor ChEBI: skeletal muscle protease inhibitors ChEBI: mast cell protease I inhibitor ChEBI: EC 3.4.21.39 inhibitors ChEBI: skeletal muscle protease inhibitor ChEBI: SK protease inhibitor ChEBI: skin chymotryptic proteinase inhibitors ChEBI: chymase inhibitors ChEBI: skeletal muscle (SK) protease inhibitors ChEBI: SK protease inhibitors ChEBI: skeletal muscle (SK) protease inhibitor ChEBI: mast cell protease I inhibitors ChEBI: EC 3.4.21.39 inhibitor arachidonate 5-lipoxygenase inhibitor 5-LOX inhibitor 5-LOX inhibitors 5-lipoxygenase inhibitor 5-lipoxygenase inhibitors 5delta-lipoxygenase inhibitor 5delta-lipoxygenase inhibitors A lipoxygenase inhibitor that interferes with the action of arachidonate 5-lipoxygenase (EC 1.13.11.34). C-5-lipoxygenase inhibitor C-5-lipoxygenase inhibitors CHEBI:64964 EC 1.13.11.34 inhibitor EC 1.13.11.34 inhibitors LTA synthase inhibitor LTA synthase inhibitors arachidonate 5-lipoxygenase inhibitors arachidonic 5-lipoxygenase inhibitor arachidonic 5-lipoxygenase inhibitors arachidonic acid 5-lipoxygenase inhibitor arachidonic acid 5-lipoxygenase inhibitors chebi_ontology delta(5)-lipoxygenase inhibitor delta(5)-lipoxygenase inhibitors leukotriene A4 synthase inhibitor leukotriene A4 synthase inhibitors leukotriene-A4 synthase inhibitor leukotriene-A4 synthase inhibitors ChEBI: leukotriene A4 synthase inhibitors ChEBI: arachidonate 5-lipoxygenase inhibitors 5-lipoxygenase inhibitor ChEBI: 5-lipoxygenase inhibitors ChEBI: ChEBI: leukotriene A4 synthase inhibitor 5-LOX inhibitor ChEBI: ChEBI: EC 1.13.11.34 inhibitors ChEBI: delta(5)-lipoxygenase inhibitor ChEBI: LTA synthase inhibitors ChEBI: arachidonic acid 5-lipoxygenase inhibitors ChEBI: arachidonic 5-lipoxygenase inhibitor 5-LOX inhibitors ChEBI: ChEBI: arachidonic acid 5-lipoxygenase inhibitor ChEBI: leukotriene-A4 synthase inhibitor ChEBI: delta(5)-lipoxygenase inhibitors 5delta-lipoxygenase inhibitor ChEBI: C-5-lipoxygenase inhibitors ChEBI: ChEBI: leukotriene-A4 synthase inhibitors ChEBI: EC 1.13.11.34 inhibitor ChEBI: LTA synthase inhibitor ChEBI: arachidonic 5-lipoxygenase inhibitors 5delta-lipoxygenase inhibitors ChEBI: C-5-lipoxygenase inhibitor ChEBI: arachidonate 12-lipoxygenase inhibitor 12-LOX inhibitor 12-LOX inhibitors 12-lipoxygenase inhibitor 12-lipoxygenase inhibitors 12S-lipoxygenase inhibitor 12S-lipoxygenase inhibitors 5delta-lipoxygenase inhibitor 5delta-lipoxygenase inhibitors A lipoxygenase inhibitor that interferes with the action of arachidonate 12-lipoxygenase (EC 1.13.11.31). C-5-lipoxygenase inhibitor C-5-lipoxygenase inhibitors CHEBI:64995 EC 1.13.11.31 inhibitor EC 1.13.11.31 inhibitors LTA4 synthase inhibitor LTA4 synthase inhibitors arachidonate 12-lipoxygenase inhibitors chebi_ontology delta(12)-lipoxygenase inhibitor delta(12)-lipoxygenase inhibitors leukotriene A4 synthase inhibitor leukotriene A4 synthase inhibitors 5delta-lipoxygenase inhibitors ChEBI: ChEBI: delta(12)-lipoxygenase inhibitors C-5-lipoxygenase inhibitor ChEBI: ChEBI: delta(12)-lipoxygenase inhibitor C-5-lipoxygenase inhibitors ChEBI: ChEBI: leukotriene A4 synthase inhibitor ChEBI: LTA4 synthase inhibitor ChEBI: EC 1.13.11.31 inhibitor ChEBI: LTA4 synthase inhibitors 5delta-lipoxygenase inhibitor ChEBI: ChEBI: leukotriene A4 synthase inhibitors 12-LOX inhibitors ChEBI: ChEBI: arachidonate 12-lipoxygenase inhibitors ChEBI: EC 1.13.11.31 inhibitors 12S-lipoxygenase inhibitors ChEBI: 12S-lipoxygenase inhibitor ChEBI: 12-lipoxygenase inhibitor ChEBI: 12-lipoxygenase inhibitors ChEBI: 12-LOX inhibitor ChEBI: arachidonate 15-lipoxygenase inhibitor 15-LOX inhibitor 15-LOX inhibitors 15-lipoxygenase inhibitor 15-lipoxygenase inhibitors A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33). CHEBI:64996 EC 1.13.11.33 inhibitor EC 1.13.11.33 inhibitors arachidonate 15-lipoxygenase inhibitors arachidonate:oxygen 15-oxidoreductase inhibitor arachidonate:oxygen 15-oxidoreductase inhibitors chebi_ontology linoleic acid omega(6)-lipoxygenase inhibitor linoleic acid omega(6)-lipoxygenase inhibitors omega(6) lipoxygenase inhibitor omega(6) lipoxygenase inhibitors 15-lipoxygenase inhibitors ChEBI: ChEBI: arachidonate 15-lipoxygenase inhibitors ChEBI: omega(6) lipoxygenase inhibitors ChEBI: arachidonate:oxygen 15-oxidoreductase inhibitor ChEBI: linoleic acid omega(6)-lipoxygenase inhibitor 15-LOX inhibitor ChEBI: ChEBI: EC 1.13.11.33 inhibitors 15-LOX inhibitors ChEBI: ChEBI: linoleic acid omega(6)-lipoxygenase inhibitors ChEBI: arachidonate:oxygen 15-oxidoreductase inhibitors ChEBI: omega(6) lipoxygenase inhibitor ChEBI: EC 1.13.11.33 inhibitor 15-lipoxygenase inhibitor ChEBI: triacylglycerol lipase inhibitor Any compound that inhibits the action of triacylglycerol lipase (EC 3.1.1.3). CHEBI:65001 EC 3.1.1.3 inhibitor EC 3.1.1.3 inhibitors GEH inhibitor GEH inhibitors PPL inhibitor PPL inhibitors Tween hydrolase inhibitor Tween hydrolase inhibitors Tweenase inhibitor Tweenase inhibitors Tweenesterase inhibitor Tweenesterase inhibitors butyrinase inhibitor butyrinase inhibitors cacordase inhibitor cacordase inhibitors capalase L inhibitor capalase L inhibitors chebi_ontology glycerol ester hydrolase inhibitor glycerol ester hydrolase inhibitors glycerol-ester hydrolase inhibitor glycerol-ester hydrolase inhibitors heparin releasable hepatic lipase inhibitor heparin releasable hepatic lipase inhibitors hepatic lipase inhibitor hepatic lipase inhibitors hepatic monoacylglycerol acyltransferase inhibitor hepatic monoacylglycerol acyltransferase inhibitors lipase inhibitor lipase inhibitors lipazin inhibitor lipazin inhibitors liver lipase inhibitor liver lipase inhibitors pancreatic lipase inhibitor pancreatic lipase inhibitors pancreatic triacylglycerol lipase inhibitor pancreatic triacylglycerol lipase inhibitors post-heparin plasma protamine-resistant lipase inhibitor post-heparin plasma protamine-resistant lipase inhibitors salt-resistant post-heparin lipase inhibitor salt-resistant post-heparin lipase inhibitors steapsin inhibitor steapsin inhibitors triacetinase inhibitor triacetinase inhibitors triacylglycerol ester hydrolase inhibitor triacylglycerol ester hydrolase inhibitors triacylglycerol lipase inhibitors tributyrase inhibitor tributyrase inhibitors tributyrin esterase inhibitor tributyrin esterase inhibitors tributyrinase inhibitor tributyrinase inhibitors triglyceridase inhibitor triglyceridase inhibitors triglyceride hydrolase inhibitor triglyceride hydrolase inhibitors triglyceride lipase inhibitor triglyceride lipase inhibitors triolein hydrolase inhibitor triolein hydrolase inhibitors tween-hydrolysing esterase inhibitor tween-hydrolyzing esterase inhibitors ChEBI: triacetinase inhibitor ChEBI: tween-hydrolyzing esterase inhibitors ChEBI: hepatic lipase inhibitors ChEBI: triacetinase inhibitors ChEBI: Tween hydrolase inhibitor ChEBI: hepatic monoacylglycerol acyltransferase inhibitors ChEBI: liver lipase inhibitor ChEBI: triacylglycerol lipase inhibitors ChEBI: triolein hydrolase inhibitors ChEBI: tributyrin esterase inhibitors ChEBI: PPL inhibitor ChEBI: post-heparin plasma protamine-resistant lipase inhibitor ChEBI: triglyceride hydrolase inhibitors ChEBI: post-heparin plasma protamine-resistant lipase inhibitors ChEBI: lipase inhibitors ChEBI: triolein hydrolase inhibitor ChEBI: pancreatic lipase inhibitor ChEBI: glycerol-ester hydrolase inhibitors ChEBI: butyrinase inhibitors ChEBI: GEH inhibitor ChEBI: lipazin inhibitors ChEBI: triglyceridase inhibitors ChEBI: pancreatic triacylglycerol lipase inhibitor ChEBI: pancreatic lipase inhibitors ChEBI: tributyrin esterase inhibitor ChEBI: Tween hydrolase inhibitors ChEBI: lipazin inhibitor ChEBI: triglyceride lipase inhibitor ChEBI: triglyceride hydrolase inhibitor ChEBI: tween-hydrolysing esterase inhibitor ChEBI: triacylglycerol ester hydrolase inhibitor ChEBI: steapsin inhibitors ChEBI: steapsin inhibitor ChEBI: tributyrinase inhibitors ChEBI: salt-resistant post-heparin lipase inhibitors ChEBI: glycerol ester hydrolase inhibitor ChEBI: cacordase inhibitors ChEBI: capalase L inhibitors ChEBI: Tweenesterase inhibitor ChEBI: salt-resistant post-heparin lipase inhibitor ChEBI: hepatic monoacylglycerol acyltransferase inhibitor ChEBI: triacylglycerol ester hydrolase inhibitors ChEBI: glycerol-ester hydrolase inhibitor ChEBI: liver lipase inhibitors ChEBI: tributyrinase inhibitor ChEBI: lipase inhibitor ChEBI: PPL inhibitors ChEBI: EC 3.1.1.3 inhibitor ChEBI: triglyceride lipase inhibitors ChEBI: heparin releasable hepatic lipase inhibitors ChEBI: butyrinase inhibitor ChEBI: Tweenase inhibitor ChEBI: cacordase inhibitor ChEBI: capalase L inhibitor ChEBI: Tweenase inhibitors ChEBI: Tweenesterase inhibitors ChEBI: tributyrase inhibitors ChEBI: triglyceridase inhibitor ChEBI: hepatic lipase inhibitor ChEBI: EC 3.1.1.3 inhibitors ChEBI: glycerol ester hydrolase inhibitors ChEBI: heparin releasable hepatic lipase inhibitor ChEBI: GEH inhibitors ChEBI: tributyrase inhibitor ChEBI: pancreatic triacylglycerol lipase inhibitors anti-asthmatic agent Any compound that has anti-asthmatic effects. CHEBI:65023 anti-asthmatic agents antiasthmatic agent antiasthmatic agents chebi_ontology ChEBI: antiasthmatic agent ChEBI: anti-asthmatic agents ChEBI: antiasthmatic agents arginine decarboxylase inhibitor ADC inhibitor ADC inhibitors An enzyme inhibitor that interferes with the action of arginine decarboxylase. CHEBI:65053 arginine decarboxylase inhibitors chebi_ontology ADC inhibitor ChEBI: ADC inhibitors ChEBI: ChEBI: arginine decarboxylase inhibitors fructose-bisphosphatase inhibitor An enzyme inhibitor that interferes with the action of fructose-bisphosphatase (EC 3.1.3.11). CHEBI:65056 D-fructose 1,6-diphosphatase inhibitor D-fructose 1,6-diphosphatase inhibitors D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitor D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitors D-fructose-1,6-bisphosphate phosphatase inhibitor D-fructose-1,6-bisphosphate phosphatase inhibitors EC 3.1.3.11 inhibitor EC 3.1.3.11 inhibitors FBPase inhibitor FBPase inhibitors chebi_ontology fructose 1,6-bisphosphatase inhibitor fructose 1,6-bisphosphatase inhibitors fructose 1,6-bisphosphate 1-phosphatase inhibitor fructose 1,6-bisphosphate 1-phosphatase inhibitors fructose 1,6-bisphosphate phosphatase inhibitor fructose 1,6-bisphosphate phosphatase inhibitors fructose 1,6-diphosphatase inhibitor fructose 1,6-diphosphatase inhibitors fructose 1,6-diphosphate phosphatase inhibitor fructose 1,6-diphosphate phosphatase inhibitors fructose bisphosphate phosphatase inhibitor fructose bisphosphate phosphatase inhibitors fructose diphosphatase inhibitor fructose diphosphatase inhibitors fructose diphosphate phosphatase inhibitor fructose diphosphate phosphatase inhibitors fructose-bisphosphatase inhibitors hexose bisphosphatase inhibitor hexose bisphosphatase inhibitors hexose diphosphatase inhibitor ChEBI: D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitors ChEBI: fructose 1,6-diphosphatase inhibitor ChEBI: fructose diphosphatase inhibitors ChEBI: fructose bisphosphate phosphatase inhibitor ChEBI: fructose 1,6-bisphosphate 1-phosphatase inhibitor ChEBI: fructose diphosphate phosphatase inhibitors ChEBI: hexose bisphosphatase inhibitor ChEBI: fructose 1,6-bisphosphatase inhibitors ChEBI: fructose 1,6-bisphosphate 1-phosphatase inhibitors ChEBI: fructose-bisphosphatase inhibitors ChEBI: D-fructose 1,6-diphosphatase inhibitor ChEBI: EC 3.1.3.11 inhibitor ChEBI: D-fructose-1,6-bisphosphate phosphatase inhibitor ChEBI: fructose 1,6-bisphosphate phosphatase inhibitor ChEBI: FBPase inhibitors ChEBI: hexose bisphosphatase inhibitors ChEBI: EC 3.1.3.11 inhibitors ChEBI: D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitor ChEBI: fructose 1,6-bisphosphatase inhibitor ChEBI: fructose bisphosphate phosphatase inhibitors ChEBI: fructose 1,6-bisphosphate phosphatase inhibitors ChEBI: FBPase inhibitor ChEBI: fructose diphosphate phosphatase inhibitor ChEBI: fructose diphosphatase inhibitor ChEBI: fructose 1,6-diphosphate phosphatase inhibitors ChEBI: D-fructose 1,6-diphosphatase inhibitors ChEBI: fructose 1,6-diphosphatase inhibitors ChEBI: fructose 1,6-diphosphate phosphatase inhibitor ChEBI: hexose diphosphatase inhibitor ChEBI: D-fructose-1,6-bisphosphate phosphatase inhibitors adenosine A1 receptor agonist An agonist at the A1 receptor. CHEBI:65057 Wikipedia:Adenosine_A1_receptor adenosine A1 receptor agonists chebi_ontology Wikipedia Wikipedia:Adenosine_A1_receptor ChEBI: adenosine A1 receptor agonists cyclopropane fatty acid synthase inhibitor An enzyme inhibitor that interferes with the action of cyclopropane fatty acid synthase. CHEBI:65064 chebi_ontology cyclopropane fatty acid synthase inhibitors ChEBI: cyclopropane fatty acid synthase inhibitors DNA adenine methyltransferase inhibitor An enzyme inhibitor that interferes with the action of DNA adenine methyltransferase. CHEBI:65065 DNA adenine methyltransferase inhibitors Dam inhibitor Dam inhibitors chebi_ontology ChEBI: Dam inhibitor ChEBI: Dam inhibitors ChEBI: DNA adenine methyltransferase inhibitors first generation antipsychotic Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased. CHEBI:65190 Wikipedia:Typical_antipsychotic chebi_ontology first generation antipsychotic agent first generation antipsychotic agents first generation antipsychotic drug first generation antipsychotic drugs first generation antipsychotics typical antipsychotic typical antipsychotic agent typical antipsychotic agents typical antipsychotic drug typical antipsychotic drugs typical antipsychotics ChEBI: typical antipsychotic drugs ChEBI: first generation antipsychotics ChEBI: typical antipsychotic agent ChEBI: first generation antipsychotic agents ChEBI: typical antipsychotic drug ChEBI: typical antipsychotic agents ChEBI: typical antipsychotic ChEBI: first generation antipsychotic agent ChEBI: first generation antipsychotic drug ChEBI: typical antipsychotics ChEBI: first generation antipsychotic drugs Wikipedia Wikipedia:Typical_antipsychotic second generation antipsychotic Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements. CHEBI:65191 atypical antipsychotic atypical antipsychotic agent atypical antipsychotic agents atypical antipsychotic drug atypical antipsychotic drugs atypical antipsychotics chebi_ontology second generation antipsychotic agent second generation antipsychotic agents second generation antipsychotic drug second generation antipsychotic drugs second generation antipsychotics ChEBI: atypical antipsychotic ChEBI: atypical antipsychotic drug ChEBI: second generation antipsychotic drug ChEBI: atypical antipsychotic agents ChEBI: atypical antipsychotic drugs ChEBI: second generation antipsychotic agents ChEBI: atypical antipsychotic agent ChEBI: second generation antipsychotics ChEBI: atypical antipsychotics ChEBI: second generation antipsychotic agent ChEBI: second generation antipsychotic drugs vascular endothelial growth factor receptor antagonist An antagonist at the vascular endothelial growth factor receptor. CHEBI:65207 VEGFR inhibitor VEGFR inhibitors Wikipedia:VEGF_receptors chebi_ontology vascular endothelial growth factor receptor antagonists vascular endothelial growth factor receptor inhibitor vascular endothelial growth factor receptor inhibitors ChEBI: VEGFR inhibitors ChEBI: VEGFR inhibitor ChEBI: vascular endothelial growth factor receptor antagonists ChEBI: vascular endothelial growth factor receptor inhibitors Wikipedia Wikipedia:VEGF_receptors ChEBI: vascular endothelial growth factor receptor inhibitor thrombin inhibitor An enzyme inhibitor that inhibits the action of thrombin, EC 2.4.21.5. CHEBI:65232 E thrombin inhibitor E thrombin inhibitors EC 3.4.21.5 inhibitor EC 3.4.21.5 inhibitors activated blood-coagulation factor II inhibitor activated blood-coagulation factor II inhibitors beta-thrombin inhibitor beta-thrombin inhibitors blood-coagulation factor IIa inhibitor blood-coagulation factor IIa inhibitors chebi_ontology factor IIa inhibitor factor IIa inhibitors fibrinogenase inhibitor fibrinogenase inhibitors gamma-thrombin inhibitor gamma-thrombin inhibitors thrombase inhibitor thrombase inhibitors thrombin inhibitors thrombin-C inhibitor thrombin-C inhibitors thrombofort inhibitor thrombofort inhibitors tropostasin inhibitor tropostasin inhibitors ChEBI: EC 3.4.21.5 inhibitor ChEBI: factor IIa inhibitor ChEBI: thrombase inhibitors ChEBI: E thrombin inhibitors ChEBI: E thrombin inhibitor ChEBI: thrombofort inhibitor ChEBI: activated blood-coagulation factor II inhibitor ChEBI: thrombin-C inhibitor ChEBI: blood-coagulation factor IIa inhibitor ChEBI: fibrinogenase inhibitor ChEBI: factor IIa inhibitors ChEBI: thrombase inhibitor ChEBI: EC 3.4.21.5 inhibitors ChEBI: beta-thrombin inhibitor ChEBI: blood-coagulation factor IIa inhibitors ChEBI: activated blood-coagulation factor II inhibitors ChEBI: fibrinogenase inhibitors ChEBI: gamma-thrombin inhibitor ChEBI: tropostasin inhibitors ChEBI: beta-thrombin inhibitors ChEBI: thrombin inhibitors ChEBI: gamma-thrombin inhibitors ChEBI: thrombofort inhibitors ChEBI: thrombin-C inhibitors ChEBI: tropostasin inhibitor golgi alpha-mannosidase II inhibitor An enzyme inhibitor that interferes with the action of golgi alpha-mannosidase II (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, EC 3.2.1.114), a key enzyme target in the development of anti-cancer therapies. CHEBI:65239 CiteXplore:18759458 chebi_ontology golgi alpha-mannosidase II inhibitors ChEBI: golgi alpha-mannosidase II inhibitors PubMed citation CiteXplore:18759458 LRH-1 agonist An agonist that binds to and activates liver receptor homologue-1 (LRH-1). CHEBI:65254 LRH-1 agonists NR5A2 agonist NR5A2 agonists Wikipedia:Liver_receptor_homolog-1 chebi_ontology liver receptor homologue-1 agonist liver receptor homologue-1 agonists ChEBI: liver receptor homologue-1 agonist ChEBI: LRH-1 agonists Wikipedia Wikipedia:Liver_receptor_homolog-1 ChEBI: NR5A2 agonists ChEBI: liver receptor homologue-1 agonists ChEBI: NR5A2 agonist food preservative CHEBI:65255 Substances which are added to food in order to prevent decomposition by microbial growth or by undesirable chemical changes. chebi_ontology food preservatives ChEBI: food preservatives antimicrobial preservative A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. CHEBI:65256 antimicrobial food preservative antimicrobial food preservatives antimicrobial preservatives chebi_ontology ChEBI: antimicrobial preservatives ChEBI: antimicrobial food preservative ChEBI: antimicrobial food preservatives GABA antagonist A compound that inhibits the action of gamma-aminobutyric acid. CHEBI:65259 GABA antagonists Wikipedia:GABA_antagonist chebi_ontology gamma-aminobutyric acid receptor antagonist gamma-aminobutyric acid receptor antagonists ChEBI: GABA antagonists ChEBI: gamma-aminobutyric acid receptor antagonist Wikipedia Wikipedia:GABA_antagonist ChEBI: gamma-aminobutyric acid receptor antagonists antacid Any substance which is used to neutralise stomach acidity. CHEBI:65265 Wikipedia:Antacid antacids chebi_ontology ChEBI: antacids Wikipedia Wikipedia:Antacid erythropeotin receptor agonist An agonist that binds to and activates erythropeotin receptors. CHEBI:66894 Wikipedia:Erythropoietin_receptor chebi_ontology erythropeotin receptor agonist erythropoiesis-stimulating agent erythropoiesis-stimulating agents Wikipedia Wikipedia:Erythropoietin_receptor ChEBI: erythropeotin receptor agonist ChEBI: erythropoiesis-stimulating agent ChEBI: erythropoiesis-stimulating agents prostaglandin receptor agonist An agonist that binds to and activates prostaglandin receptors. CHEBI:66900 chebi_ontology prostaglandin receptor agonists ChEBI: prostaglandin receptor agonists CFTR potentiator A membrane transport modulator that restores the chloride ion transport ability of defective cystic fibrosis transmembrane conductance regulator (CFTR) genes. CFTR potentiators CHEBI:66902 chebi_ontology cystic fibrosis transmembrane conductance regulator potentiator cystic fibrosis transmembrane conductance regulator potentiators ChEBI: cystic fibrosis transmembrane conductance regulator potentiators CFTR potentiators ChEBI: ChEBI: cystic fibrosis transmembrane conductance regulator potentiator SMO receptor antagonist An antagonist that interferes with the action of smoothened (SMO) receptor CHEBI:66908 SMO receptor antagonists Wikipedia:Smoothened chebi_ontology smoothened antagonist smoothened antagonists smoothened receptor antagonist smoothened receptor antagonists Wikipedia Wikipedia:Smoothened ChEBI: SMO receptor antagonists ChEBI: smoothened antagonist ChEBI: smoothened receptor antagonist ChEBI: smoothened antagonists ChEBI: smoothened receptor antagonists Janus kinase inhibitor A tyrosine kinase inhibitor that specifically blocks the action of Janus kinase. CHEBI:66921 Janus kinase inhibitors Wikipedia:Janus_kinase chebi_ontology Wikipedia Wikipedia:Janus_kinase ChEBI: Janus kinase inhibitors antidyskinesia agent Any compound which can be used to treat or alleviate the symptoms of dyskinesia. CHEBI:66956 antidyskinesia agents antidyskinesia drug antidyskinesia drugs antidyskinetic agent antidyskinetic agents antidyskinetic drug antidyskinetic drugs chebi_ontology ChEBI: antidyskinesia drugs ChEBI: antidyskinetic drug ChEBI: antidyskinetic agent ChEBI: antidyskinetic drugs ChEBI: antidyskinetic agents ChEBI: antidyskinesia agents ChEBI: antidyskinesia drug nootropic agent Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration. CHEBI:66980 CiteXplore:22393531 CiteXplore:22647316 CiteXplore:22742585 CiteXplore:22795553 CiteXplore:22828638 CiteXplore:22837964 Wikipedia:Nootropic chebi_ontology cognitive enhancer cognitive enhancers intelligence enhancer intelligence enhancers memory enhancer memory enhancers neuro enhancer neuro enhancers nootropic nootropic agents nootropic drug nootropic drugs nootropics smart drug smart drugs ChEBI: memory enhancer PubMed citation CiteXplore:22647316 ChEBI: smart drug ChEBI: neuro enhancer ChEBI: cognitive enhancer PubMed citation CiteXplore:22837964 ChEBI: nootropic ChEBI: nootropic agents ChEBI: nootropics ChEBI: nootropic drugs ChEBI: cognitive enhancers Wikipedia Wikipedia:Nootropic PubMed citation CiteXplore:22828638 PubMed citation CiteXplore:22393531 ChEBI: intelligence enhancer ChEBI: neuro enhancers PubMed citation CiteXplore:22742585 ChEBI: smart drugs ChEBI: memory enhancers ChEBI: intelligence enhancers ChEBI: nootropic drug PubMed citation CiteXplore:22795553 ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. CHEBI:66981 chebi_ontology ophthalmic ophthalmic agent ophthalmic agents ophthalmics ophthalmological ophthalmologicals ophthalmology agent ophthalmology agents ophthalmology drugs ChEBI: ophthalmologicals ChEBI: ophthalmology agent ChEBI: ophthalmology drugs ChEBI: ophthalmic agent ChEBI: ophthalmological ChEBI: ophthalmology agents ChEBI: ophthalmic agents ChEBI: ophthalmic ChEBI: ophthalmics radiation protective agent CHEBI:66987 chebi_ontology sympatholytic agent Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS). CHEBI:66991 Wikipedia:Sympatholytic chebi_ontology sympatholytic sympatholytic agents sympatholytic drug sympatholytic drugs sympatholytics ChEBI: sympatholytic drugs Wikipedia Wikipedia:Sympatholytic ChEBI: sympatholytic drug ChEBI: sympatholytics ChEBI: sympatholytic agents ChEBI: sympatholytic tocolytic agent Any compound used to suppress premature labour and immature birth by suppressing uterine contractions. CHEBI:66993 Wikipedia:Tocolytic anti-contraction drug anti-contraction drugs anti-contraction medication anti-contraction medications chebi_ontology labour repressant labour repressants tocolytic tocolytic agents tocolytic drug tocolytic drugs tocolytics ChEBI: anti-contraction medication ChEBI: anti-contraction drug Wikipedia Wikipedia:Tocolytic ChEBI: tocolytic agents ChEBI: labour repressants ChEBI: anti-contraction drugs ChEBI: tocolytic drug ChEBI: tocolytic drugs ChEBI: tocolytics ChEBI: anti-contraction medications ChEBI: tocolytic ChEBI: labour repressant cannabinoid receptor agonist An agonist that binds to and activates cannabinoid receptors. CHEBI:67072 Wikipedia:Cannabinoid_receptor cannabinoid receptor agonists chebi_ontology ChEBI: cannabinoid receptor agonists Wikipedia Wikipedia:Cannabinoid_receptor anti-inflammatory agent Any compound that has anti-inflammatory effects. CHEBI:67079 anti-inflammatory agents antiinflammatory agent antiinflammatory agents chebi_ontology ChEBI: antiinflammatory agent ChEBI: anti-inflammatory agents ChEBI: antiinflammatory agents insect sterilant A chemosterilant intended to sterilize insects. CHEBI:67105 chebi_ontology insect chemosterilant insect chemosterilants insect sterilants ChEBI: insect sterilants ChEBI: insect chemosterilants ChEBI: insect chemosterilant ryanodine receptor agonist A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction. CHEBI:67114 RyR activator RyR activators RyR agonist RyR agonists RyRs activator RyRs agonist Wikipedia:Ryanodine_receptor chebi_ontology ryanodine receptor activator ryanodine receptor activators ChEBI: RyRs agonist ChEBI: ryanodine receptor activator ChEBI: ryanodine receptor activators ChEBI: RyRs activator ChEBI: RyR activators ChEBI: RyR activator ChEBI: RyR agonists ChEBI: RyR agonist Wikipedia Wikipedia:Ryanodine_receptor colorimetric reagent A reagent used in the determination of the concentration of a coloured chemical element or chemical compound in solution. CHEBI:67126 chebi_ontology color reagent color reagents colorimetric reagents colour reagent colour reagents ChEBI: colour reagent ChEBI: color reagent ChEBI: color reagents ChEBI: colour reagents ChEBI: colorimetric reagents NMR shift reagent CHEBI:67137 In NMR spectroscopy a reagent added to a solution to induce chemical shifts and thus simplify complex spectra. NMR shift reagents chebi_ontology lanthanide shift reagent lanthanide shift reagents nuclear magnetic resonance shift reagent nuclear magnetic resonance shift reagents ChEBI: lanthanide shift reagent ChEBI: nuclear magnetic resonance shift reagent ChEBI: lanthanide shift reagents ChEBI: NMR shift reagents ChEBI: nuclear magnetic resonance shift reagents anti-angiogenic agent Any compound that inhibits the growth of new blood vessels from pre-existing vessels. CHEBI:67170 anti-angiogenic agents antiangiogenic agent antiangiogenic agents chebi_ontology ChEBI: antiangiogenic agents ChEBI: antiangiogenic agent ChEBI: anti-angiogenic agents microbial collagenase inhibitor Achromobacter iophagus collagenase inhibitor Achromobacter iophagus collagenase inhibitors An enzyme inhibitor which inhibits the action of microbial collagenase (EC 3.4.24.3, also formerly EC 3.4.4.19 and EC 3.4.99.5) CHEBI:67189 Clostridium histolyticum collagenase inhibitor Clostridium histolyticum collagenase inhibitors Clostridium histolyticum proteinase A inhibitor Clostridium histolyticum proteinase A inhibitors EC 3.4.24.3 inhibitor EC 3.4.24.3 inhibitors MMP-1 inhibitor MMP-1 inhibitors MMP-8 inhibitor MMP-8 inhibitors aspergillopeptidase C inhibitor aspergillopeptidase C inhibitors azocollase inhibitor azocollase inhibitors chebi_ontology clostridiopeptidase A inhibitor clostridiopeptidase A inhibitors clostridiopeptidase I inhibitor clostridiopeptidase I inhibitors clostridiopeptidase II inhibitor clostridiopeptidase II inhibitors collagen peptidase inhibitor collagen peptidase inhibitors collagen protease inhibitor collagen protease inhibitors collagenase A inhibitor collagenase A inhibitors collagenase I inhibitor collagenase I inhibitors collagenase MMP-1 inhibitor collagenase MMP-1 inhibitors collagenase inhibitor collagenase inhibitors interstitial collagenase inhibitor interstitial collagenase inhibitors kollaza inhibitor kollaza inhibitors matrix metalloproteinase-1 inhibitor matrix metalloproteinase-1 inhibitors matrix metalloproteinase-18 inhibitor matrix metalloproteinase-18 inhibitors matrix metalloproteinase-8 inhibitor matrix metalloproteinase-8 inhibitors metallocollagenase inhibitor metallocollagenase inhibitors metalloproteinase-1 inhibitor metalloproteinase-1 inhibitors microbial collagenase inhibitors nucleolysin inhibitor nucleolysin inhibitors soycollagestin inhibitor soycollagestin inhibitors ChEBI: collagenase inhibitor ChEBI: clostridiopeptidase I inhibitors ChEBI: clostridiopeptidase A inhibitors Achromobacter iophagus collagenase inhibitor ChEBI: ChEBI: clostridiopeptidase A inhibitor ChEBI: clostridiopeptidase II inhibitors ChEBI: collagenase I inhibitor ChEBI: matrix metalloproteinase-8 inhibitor ChEBI: metalloproteinase-1 inhibitor ChEBI: clostridiopeptidase I inhibitor ChEBI: matrix metalloproteinase-18 inhibitor ChEBI: Clostridium histolyticum proteinase A inhibitor ChEBI: Clostridium histolyticum proteinase A inhibitors ChEBI: MMP-1 inhibitors ChEBI: metallocollagenase inhibitor ChEBI: metallocollagenase inhibitors ChEBI: nucleolysin inhibitors ChEBI: collagenase A inhibitors ChEBI: interstitial collagenase inhibitors ChEBI: Clostridium histolyticum collagenase inhibitor ChEBI: collagenase A inhibitor ChEBI: aspergillopeptidase C inhibitors ChEBI: matrix metalloproteinase-1 inhibitors ChEBI: azocollase inhibitors ChEBI: nucleolysin inhibitor ChEBI: EC 3.4.24.3 inhibitor ChEBI: MMP-8 inhibitors ChEBI: collagenase I inhibitors ChEBI: kollaza inhibitor ChEBI: aspergillopeptidase C inhibitor ChEBI: collagenase MMP-1 inhibitor ChEBI: kollaza inhibitors ChEBI: clostridiopeptidase II inhibitor ChEBI: collagen peptidase inhibitors ChEBI: MMP-1 inhibitor ChEBI: azocollase inhibitor ChEBI: soycollagestin inhibitors ChEBI: collagen peptidase inhibitor ChEBI: soycollagestin inhibitor ChEBI: matrix metalloproteinase-8 inhibitors ChEBI: metalloproteinase-1 inhibitors ChEBI: microbial collagenase inhibitors ChEBI: collagen protease inhibitors ChEBI: matrix metalloproteinase-1 inhibitor ChEBI: collagenase MMP-1 inhibitors ChEBI: Clostridium histolyticum collagenase inhibitors ChEBI: collagenase inhibitors ChEBI: EC 3.4.24.3 inhibitors ChEBI: interstitial collagenase inhibitor ChEBI: MMP-8 inhibitor ChEBI: collagen protease inhibitor ChEBI: matrix metalloproteinase-18 inhibitors Achromobacter iophagus collagenase inhibitors ChEBI: gap junctional intercellular communication inhibitor An inhibitor that interferes with the process of gap junctional intercellular communication. CHEBI:67195 Wikipedia:Gap_junction chebi_ontology gap junctional intercellular communication inhibitors ChEBI: gap junctional intercellular communication inhibitors Wikipedia Wikipedia:Gap_junction retinoic acid receptor agonist An agonist that selectively binds to and activates a retinoic acid receptor. CHEBI:67198 Wikipedia:Retinoic_acid_receptor chebi_ontology retinoic acid receptor agonists Wikipedia Wikipedia:Retinoic_acid_receptor ChEBI: retinoic acid receptor agonists AP-1 antagonist AP-1 antagonists An antogonist that interferes with the action of activator protein 1 (AP-1). CHEBI:67199 Wikipedia:Activator_protein_1 activator protein-1 antagonist activator protein-1 antagonists chebi_ontology ChEBI: activator protein-1 antagonists AP-1 antagonists ChEBI: ChEBI: activator protein-1 antagonist Wikipedia Wikipedia:Activator_protein_1 provitamin A A provitamin that can be converted into vitamin A by enzymes from animal tissues. CHEBI:67200 chebi_ontology provitamin As ChEBI: provitamin As glucosylceramidase inhibitor An enzyme inhibitor that inhibits the action of glucosylceramidase (EC 3.2.1.45). CHEBI:67230 D-glucosyl-N-acylsphingosine glucohydrolase inhibitor D-glucosyl-N-acylsphingosine glucohydrolase inhibitors EC 3.2.1.45 inhibitor EC 3.2.1.45 inhibitors GlcCer-beta-glucosidase inhibitor GlcCer-beta-glucosidase inhibitors Wikipedia:Glucosylceramidase acid beta-glucosidase inhibitor acid beta-glucosidase inhibitors acid-beta-glucosidase inhibitor acid-beta-glucosidase inhibitors beta-D-glucocerebrosidase inhibitor beta-D-glucocerebrosidase inhibitors beta-glucosylceramidase inhibitor beta-glucosylceramidase inhibitors ceramide glucosidase inhibitor ceramide glucosidase inhibitors chebi_ontology glucocerebrosidase inhibitor glucocerebrosidase inhibitors glucosphingosine glucosylhydrolase inhibitor glucosphingosine glucosylhydrolase inhibitors glucosylceramidase inhibitors glucosylcerebrosidase inhibitor glucosylcerebrosidase inhibitors glucosylsphingosine beta-D-glucosidase inhibitor glucosylsphingosine beta-D-glucosidase inhibitors glucosylsphingosine beta-glucosidase inhibitor glucosylsphingosine beta-glucosidase inhibitors psychosine hydrolase inhibitor psychosine hydrolase inhibitors ChEBI: EC 3.2.1.45 inhibitor ChEBI: EC 3.2.1.45 inhibitors ChEBI: acid beta-glucosidase inhibitor Wikipedia Wikipedia:Glucosylceramidase ChEBI: ceramide glucosidase inhibitors ChEBI: glucosphingosine glucosylhydrolase inhibitor ChEBI: glucosylsphingosine beta-D-glucosidase inhibitor ChEBI: GlcCer-beta-glucosidase inhibitors ChEBI: beta-D-glucocerebrosidase inhibitors ChEBI: acid-beta-glucosidase inhibitors ChEBI: glucosylcerebrosidase inhibitors ChEBI: glucocerebrosidase inhibitors ChEBI: beta-D-glucocerebrosidase inhibitor ChEBI: GlcCer-beta-glucosidase inhibitor ChEBI: D-glucosyl-N-acylsphingosine glucohydrolase inhibitors ChEBI: psychosine hydrolase inhibitors ChEBI: glucosphingosine glucosylhydrolase inhibitors ChEBI: beta-glucosylceramidase inhibitors ChEBI: glucosylsphingosine beta-D-glucosidase inhibitors ChEBI: D-glucosyl-N-acylsphingosine glucohydrolase inhibitor ChEBI: ceramide glucosidase inhibitor ChEBI: psychosine hydrolase inhibitor ChEBI: glucocerebrosidase inhibitor ChEBI: acid beta-glucosidase inhibitors ChEBI: beta-glucosylceramidase inhibitor ChEBI: glucosylsphingosine beta-glucosidase inhibitor ChEBI: glucosylceramidase inhibitors ChEBI: glucosylcerebrosidase inhibitor ChEBI: glucosylsphingosine beta-glucosidase inhibitors ChEBI: acid-beta-glucosidase inhibitor sucrose alpha-glucosidase inhibitor An enzyme inhibitor that inhibits the action of sucrose alpha-glucosidase (EC 3.2.1.48). CHEBI:67231 EC 3.2.1.48 inhibitor EC 3.2.1.48 inhibitors chebi_ontology intestinal sucrase inhibitor intestinal sucrase inhibitors sucrase (invertase) inhibitor sucrase (invertase) inhibitors sucrase inhibitor sucrase inhibitors sucrase-isomaltase inhibitor sucrase-isomaltase inhibitors sucrose alpha-glucohydrolase inhibitor sucrose alpha-glucohydrolase inhibitors sucrose alpha-glucosidase inhibitors sucrose-alpha-D-glucohydrolase inhibitor sucrose-alpha-D-glucohydrolase inhibitors ChEBI: sucrase (invertase) inhibitor ChEBI: sucrase inhibitor ChEBI: sucrose-alpha-D-glucohydrolase inhibitor ChEBI: sucrase-isomaltase inhibitor ChEBI: sucrose alpha-glucosidase inhibitors ChEBI: sucrase (invertase) inhibitors ChEBI: sucrose alpha-glucohydrolase inhibitor ChEBI: intestinal sucrase inhibitor ChEBI: sucrase inhibitors ChEBI: sucrase-isomaltase inhibitors ChEBI: intestinal sucrase inhibitors ChEBI: EC 3.2.1.48 inhibitors ChEBI: EC 3.2.1.48 inhibitor ChEBI: sucrose alpha-glucohydrolase inhibitors ChEBI: sucrose-alpha-D-glucohydrolase inhibitors oligo-1,6-glucosidase inhibitor An enzyme inhibitor that inhibits the action of sucrose oligo-1,6-glucosidase (EC 3.2.1.10). CHEBI:67232 EC 3.2.1.10 inhibitor EC 3.2.1.10 inhibitors alpha-limit dextrinase inhibitor alpha-limit dextrinase inhibitors chebi_ontology dextrin 6-glucanohydrolase inhibitor dextrin 6-glucanohydrolase inhibitors dextrin 6alpha-glucanohydrolase inhibitor dextrin 6alpha-glucanohydrolase inhibitors exo-oligo-1,6-glucosidase inhibitor exo-oligo-1,6-glucosidase inhibitors isomaltase inhibitor isomaltase inhibitors oligo-1,6-glucosidase inhibitors oligosaccharide alpha-1,6-glucohydrolase inhibitor oligosaccharide alpha-1,6-glucohydrolase inhibitors sucrase-isomaltase inhibitor sucrase-isomaltase inhibitors ChEBI: alpha-limit dextrinase inhibitor ChEBI: dextrin 6alpha-glucanohydrolase inhibitor ChEBI: sucrase-isomaltase inhibitors ChEBI: oligo-1,6-glucosidase inhibitors ChEBI: dextrin 6-glucanohydrolase inhibitor ChEBI: dextrin 6-glucanohydrolase inhibitors ChEBI: alpha-limit dextrinase inhibitors ChEBI: isomaltase inhibitors ChEBI: isomaltase inhibitor ChEBI: dextrin 6alpha-glucanohydrolase inhibitors ChEBI: EC 3.2.1.10 inhibitors ChEBI: exo-oligo-1,6-glucosidase inhibitors ChEBI: sucrase-isomaltase inhibitor ChEBI: EC 3.2.1.10 inhibitor ChEBI: exo-oligo-1,6-glucosidase inhibitor ChEBI: oligosaccharide alpha-1,6-glucohydrolase inhibitor ChEBI: oligosaccharide alpha-1,6-glucohydrolase inhibitors alpha-glucosidase inhibitor An enzyme inhibitor that inhibits the action of alpha-glucosidase (EC 3.2.1.20). CHEBI:67239 EC 3.2.1.20 inhibitor EC 3.2.1.20 inhibitors alpha-1,4-glucosidase inhibitor alpha-1,4-glucosidase inhibitors alpha-D-glucosidase inhibitor alpha-D-glucosidase inhibitors alpha-glucopyranosidase inhibitor alpha-glucopyranosidase inhibitors alpha-glucosidase inhibitors alpha-glucoside hydrolase inhibitor alpha-glucoside hydrolase inhibitors chebi_ontology glucoinvertase inhibitor glucoinvertase inhibitors glucosidoinvertase inhibitor glucosidoinvertase inhibitors glucosidosucrase inhibitor glucosidosucrase inhibitors maltase inhibitor maltase inhibitors maltase-glucoamylase inhibitor maltase-glucoamylase inhibitors ChEBI: glucosidoinvertase inhibitor ChEBI: alpha-glucopyranosidase inhibitors ChEBI: maltase inhibitor ChEBI: glucosidosucrase inhibitors ChEBI: alpha-glucoside hydrolase inhibitor ChEBI: alpha-1,4-glucosidase inhibitors ChEBI: alpha-glucopyranosidase inhibitor ChEBI: EC 3.2.1.20 inhibitors ChEBI: glucoinvertase inhibitors ChEBI: alpha-D-glucosidase inhibitors ChEBI: glucosidosucrase inhibitor ChEBI: alpha-glucosidase inhibitors ChEBI: glucoinvertase inhibitor ChEBI: maltase-glucoamylase inhibitor ChEBI: EC 3.2.1.20 inhibitor ChEBI: alpha-1,4-glucosidase inhibitor ChEBI: maltase-glucoamylase inhibitors ChEBI: alpha-D-glucosidase inhibitor ChEBI: glucosidoinvertase inhibitors ChEBI: maltase inhibitors ChEBI: alpha-glucoside hydrolase inhibitors geranylgeranyltransferase type I inhibitor An enzyme inhibitor that interferes with the action of geranylgeranyltransferase type I (EC 2.5.1.59). CHEBI:67267 GGTase I inhibitor GGTase I inhibitors chebi_ontology geranylgeranyltransferase type I inhibitors ChEBI: GGTase I inhibitor ChEBI: GGTase I inhibitors ChEBI: geranylgeranyltransferase type I inhibitors HIV-1 integrase inhibitor An inhibitor of HIV-1 integrase, an enzyme required for the integration of the genetic material of the retrovirus into the DNA of the infected cells. CHEBI:67268 Wikipedia:Discovery_and_development_of_integrase_inhibitors chebi_ontology Wikipedia Wikipedia:Discovery_and_development_of_integrase_inhibitors mTOR inhibitor A protein kinase inhibitor of mammalian target of rapamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. They are used to prevent transplant rejection and in treatment of cancer. CHEBI:68481 Wikipedia:Mammalian_target_of_rapamycin chebi_ontology mTOR inhibitors mammalian target of rapamycin inhibitor mammalian target of rapamycin inhibitors ChEBI: mammalian target of rapamycin inhibitor ChEBI: mammalian target of rapamycin inhibitors ChEBI: mTOR inhibitors Wikipedia Wikipedia:Mammalian_target_of_rapamycin apoptosis inhibitor Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms. CHEBI:68494 Type I cell-death inhibitor Type I cell-death inhibitors Type I programmed cell-death inhibitor Type I programmed cell-death inhibitors apoptosis inhibitors chebi_ontology ChEBI: Type I cell-death inhibitor ChEBI: apoptosis inhibitors ChEBI: Type I programmed cell-death inhibitor ChEBI: Type I programmed cell-death inhibitors ChEBI: Type I cell-death inhibitors apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. CHEBI:68495 Type I cell-death inducer Type I cell-death inducers Type I programmed cell-death inducer Type I programmed cell-death inducers apoptosis inducers chebi_ontology ChEBI: Type I programmed cell-death inducers ChEBI: Type I programmed cell-death inducer ChEBI: Type I cell-death inducer ChEBI: apoptosis inducers ChEBI: Type I cell-death inducers glutathione depleting agent A compound which causes a reduction in the levels of glutathione in cells. CHEBI:68509 chebi_ontology glutathione depleting agents glutathione depletion agent glutathione depletion agents glutathione depletor glutathione depletors ChEBI: glutathione depleting agents ChEBI: glutathione depletion agents ChEBI: glutathione depletion agent ChEBI: glutathione depletor ChEBI: glutathione depletors dihydroorotate dehydrogenase inhibitor An enzyme inhibitor that interferes with the action of dihydroorotate dehydrogenase (EC 1.3.3.1). CHEBI:68542 DHODH inhibitor DHODH inhibitors Wikipedia:Dihydroorotate_dehydrogenase chebi_ontology dihydroorotate dehydrogenase inhibitors ChEBI: dihydroorotate dehydrogenase inhibitors ChEBI: DHODH inhibitor ChEBI: DHODH inhibitors Wikipedia Wikipedia:Dihydroorotate_dehydrogenase pyrimidine synthesis inhibitor An enzyme inhibitor that inhibits the synthesis of pyrimidine. CHEBI:68543 chebi_ontology pyrimidine synthesis inhibitors ChEBI: pyrimidine synthesis inhibitors guanylate cyclase 2C agonist An agonist that selectively binds to and activates guanylate cyclase 2C receptors. CHEBI:68553 GC-C agonist GC-C agonists chebi_ontology guanylate cyclase 2C agonists ChEBI: guanylate cyclase 2C agonists ChEBI: GC-C agonists ChEBI: GC-C agonist bradykinin receptor antagonist An antagonist at the bradykinin receptor. CHEBI:68557 bradykinin receptor antagonists chebi_ontology ChEBI: bradykinin receptor antagonists P2Y12 receptor antagonist ADP receptor subtype P2Y12 antagonist ADP receptor subtype P2Y12 antagonists An antagonist at the P2Y12 receptor CHEBI:68563 P2Y12 receptor antagonists Wikipedia:P2Y12 chebi_ontology purinergic receptor subtype P2Y12 antagonist purinergic receptor subtype P2Y12 antagonists ChEBI: purinergic receptor subtype P2Y12 antagonists Wikipedia Wikipedia:P2Y12 ChEBI: purinergic receptor subtype P2Y12 antagonist ChEBI: P2Y12 receptor antagonists ADP receptor subtype P2Y12 antagonist ChEBI: ADP receptor subtype P2Y12 antagonists ChEBI: coagulation factor Xa inhibitor An enzyme inhibitor that interferes with the action of coagulation factor Xa (EC 3.4.21.6) CHEBI:68581 Wikipedia:Factor_Xa_inhibitor chebi_ontology coagulation factor Xa inhibitors factor Xa inhibitor factor Xa inhibitors ChEBI: factor Xa inhibitor ChEBI: coagulation factor Xa inhibitors Wikipedia Wikipedia:Factor_Xa_inhibitor ChEBI: factor Xa inhibitors dipeptidyl peptidase-4 inhibitor A peptidase inhibitor that specifically inhibits dipeptidyl peptidase-4 (EC 3.4.14.5) CHEBI:68612 DPP IV/CD26 inhibitor DPP IV/CD26 inhibitors DPP-4 inhibitor DPP-4 inhibitors EC 3.4.14.5 inhibitor EC 3.4.14.5 inhibitors Gly-Pro naphthylamidase inhibitor Gly-Pro naphthylamidase inhibitors T cell triggering molecule Tp103 inhibitor T cell triggering molecule Tp103 inhibitors Wikipedia:Dipeptidyl_peptidase-4_inhibitor X-PDAP inhibitor X-PDAP inhibitors X-prolyl dipeptidyl aminopeptidase inhibitor X-prolyl dipeptidyl aminopeptidase inhibitors Xaa-Pro-dipeptidyl-aminopeptidase inhibitor Xaa-Pro-dipeptidyl-aminopeptidase inhibitors amino acyl-prolyl dipeptidyl aminopeptidase inhibitor amino acyl-prolyl dipeptidyl aminopeptidase inhibitors chebi_ontology dipeptidyl aminopeptidase IV inhibitor dipeptidyl aminopeptidase IV inhibitors dipeptidyl peptidase IV inhibitor dipeptidyl peptidase IV inhibitors dipeptidyl peptidase-4 inhibitors dipeptidyl-aminopeptidase IV inhibitor dipeptidyl-aminopeptidase IV inhibitors dipeptidyl-peptidase IV inhibitor dipeptidyl-peptidase IV inhibitors dipeptidyl-peptide hydrolase inhibitor dipeptidyl-peptide hydrolase inhibitors glycoprotein GP110 inhibitor glycoprotein GP110 inhibitors glycylproline aminopeptidase inhibitor glycylproline aminopeptidase inhibitors glycylprolyl aminopeptidase inhibitor glycylprolyl aminopeptidase inhibitors glycylprolyl dipeptidylaminopeptidase inhibitor glycylprolyl dipeptidylaminopeptidase inhibitors leukocyte antigen CD26 inhibitor leukocyte antigen CD26 inhibitors lymphocyte antigen CD26 inhibitor lymphocyte antigen CD26 inhibitors pep X inhibitor pep X inhibitors postproline dipeptidyl aminopeptidase IV inhibitor postproline dipeptidyl aminopeptidase IV inhibitors ChEBI: dipeptidyl peptidase IV inhibitor ChEBI: DPP IV/CD26 inhibitor ChEBI: glycylprolyl dipeptidylaminopeptidase inhibitors ChEBI: T cell triggering molecule Tp103 inhibitors ChEBI: DPP-4 inhibitor ChEBI: dipeptidyl-peptidase IV inhibitor ChEBI: DPP IV/CD26 inhibitors ChEBI: postproline dipeptidyl aminopeptidase IV inhibitor ChEBI: leukocyte antigen CD26 inhibitors ChEBI: amino acyl-prolyl dipeptidyl aminopeptidase inhibitor ChEBI: amino acyl-prolyl dipeptidyl aminopeptidase inhibitors ChEBI: pep X inhibitors ChEBI: dipeptidyl-peptide hydrolase inhibitors ChEBI: lymphocyte antigen CD26 inhibitor ChEBI: glycylprolyl dipeptidylaminopeptidase inhibitor ChEBI: dipeptidyl-peptide hydrolase inhibitor Wikipedia Wikipedia:Dipeptidyl_peptidase-4_inhibitor ChEBI: postproline dipeptidyl aminopeptidase IV inhibitors ChEBI: Gly-Pro naphthylamidase inhibitor ChEBI: glycylproline aminopeptidase inhibitor ChEBI: X-prolyl dipeptidyl aminopeptidase inhibitor ChEBI: DPP-4 inhibitors ChEBI: leukocyte antigen CD26 inhibitor ChEBI: dipeptidyl peptidase-4 inhibitors ChEBI: glycoprotein GP110 inhibitors ChEBI: glycylprolyl aminopeptidase inhibitors ChEBI: glycylproline aminopeptidase inhibitors ChEBI: dipeptidyl aminopeptidase IV inhibitor ChEBI: X-PDAP inhibitor ChEBI: dipeptidyl-aminopeptidase IV inhibitors ChEBI: X-PDAP inhibitors ChEBI: lymphocyte antigen CD26 inhibitors ChEBI: Gly-Pro naphthylamidase inhibitors ChEBI: glycylprolyl aminopeptidase inhibitor ChEBI: dipeptidyl peptidase IV inhibitors ChEBI: pep X inhibitor ChEBI: T cell triggering molecule Tp103 inhibitor ChEBI: EC 3.4.14.5 inhibitors ChEBI: Xaa-Pro-dipeptidyl-aminopeptidase inhibitor ChEBI: X-prolyl dipeptidyl aminopeptidase inhibitors ChEBI: dipeptidyl aminopeptidase IV inhibitors ChEBI: dipeptidyl-peptidase IV inhibitors ChEBI: EC 3.4.14.5 inhibitor ChEBI: dipeptidyl-aminopeptidase IV inhibitor ChEBI: Xaa-Pro-dipeptidyl-aminopeptidase inhibitors ChEBI: glycoprotein GP110 inhibitor cytochrome P450 17-alpha-hydroxylase/C17,20-lyase inhibitor CHEBI:68640 chebi_ontology phosphodiesterase IV inhibitor A phosphodiesterase inhibitor that specifically blocks the action of phosphodiesterase IV. CHEBI:68844 PDE4 inhibitor PDE4 inhibitors Wikipedia:Phosphodiesterase-4_inhibitor chebi_ontology phosphodiesterase 4 inhibitor phosphodiesterase 4 inhibitors phosphodiesterase IV inhibitors type 4 phosphodiesterase inhibitor type 4 phosphodiesterase inhibitors ChEBI: PDE4 inhibitors Wikipedia Wikipedia:Phosphodiesterase-4_inhibitor ChEBI: PDE4 inhibitor ChEBI: phosphodiesterase 4 inhibitor ChEBI: type 4 phosphodiesterase inhibitors ChEBI: phosphodiesterase IV inhibitors ChEBI: type 4 phosphodiesterase inhibitor ChEBI: phosphodiesterase 4 inhibitors progesterone receptor agonist A hormone agonist that binds to and activates progesterone receptors. CHEBI:70709 PR agonist PR agonists chebi_ontology progesterone receptor agonists ChEBI: PR agonists ChEBI: progesterone receptor agonists ChEBI: PR agonist acetyl-CoA carboxylase inhibitor ACC inhibitor ACC inhibitors ACCase inhibitor ACCase inhibitors An enzyme inhibitor that inhibits the action of acetyl-CoA carboxylase (EC 6.4.1.2). CHEBI:70722 CiteXplore:19552511 CiteXplore:22560583 CiteXplore:22677317 EC 6.4.1.2 inhibitor EC 6.4.1.2 inhibitors Patent:US2009270435 Wikipedia:Acetyl_CoA_carboxylase acetyl coenzyme A carboxylase inhibitor acetyl coenzyme A carboxylase inhibitors acetyl-CoA carboxylase inhibitors acetyl-CoA:carbon-dioxide ligase (ADP-forming) inhibitor acetyl-CoA:carbon-dioxide ligase (ADP-forming) inhibitors chebi_ontology ChEBI: acetyl-CoA carboxylase inhibitors ACC inhibitor ChEBI: Wikipedia Wikipedia:Acetyl_CoA_carboxylase PubMed citation CiteXplore:22677317 ChEBI: acetyl-CoA:carbon-dioxide ligase (ADP-forming) inhibitor ACCase inhibitors ChEBI: PubMed citation CiteXplore:19552511 ACC inhibitors ChEBI: ChEBI: acetyl coenzyme A carboxylase inhibitors ACCase inhibitor ChEBI: Patent Patent:US2009270435 ChEBI: acetyl-CoA:carbon-dioxide ligase (ADP-forming) inhibitors ChEBI: EC 6.4.1.2 inhibitor PubMed citation CiteXplore:22560583 ChEBI: EC 6.4.1.2 inhibitors ChEBI: acetyl coenzyme A carboxylase inhibitor cell dedifferentiation agent Any compound which induces a partially or terminally differentiated cell to revert to an earlier developmental stage. CHEBI:70724 cell dedifferentiation agents chebi_ontology ChEBI: cell dedifferentiation agents adenosine A3 receptor antagonist An antagonist at the A3 receptor. CHEBI:70725 Wikipedia:Adenosine_A3_receptor adenosine A3 receptor antagonistS chebi_ontology ChEBI: adenosine A3 receptor antagonistS Wikipedia Wikipedia:Adenosine_A3_receptor topoisomerase inhibitor An enzyme inhibitor that inhibits the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA). CHEBI:70727 Wikipedia:Topoisomerase chebi_ontology topoisomerase inhibitors ChEBI: topoisomerase inhibitors Wikipedia Wikipedia:Topoisomerase actin polymerisation inhibitor Any substance that inhibits the polymerisation of the protein actin. CHEBI:70728 actin polymerisation inhibitors actin polymerization inhibitor actin polymerization inhibitors chebi_ontology ChEBI: actin polymerization inhibitor ChEBI: actin polymerization inhibitors ChEBI: actin polymerisation inhibitors Aurora kinase inhibitor Any protein kinase inhibitor that inhibits the action of an Aurora kinase (a group of serine/threonine kinases that are essential for cell proliferation). Aurora kinase inhibitors CHEBI:70770 CiteXplore:19369091 CiteXplore:21147253 CiteXplore:22350019 chebi_ontology PubMed citation CiteXplore:21147253 PubMed citation CiteXplore:19369091 PubMed citation CiteXplore:22350019 Aurora kinase inhibitors ChEBI: capsaicin receptor antagonist Any substance which blocks the painful sensation of heat caused by capsaicin acting on the TRPV1 ion channel. CHEBI:70774 TRPV1 antagonist TRPV1 antagonists TrpV1 antagonist TrpV1 antagonists Wikipedia:Discovery_and_development_of_TRPV1_antagonists capsaicin antagonist capsaicin antagonists capsaicin receptor antagonists chebi_ontology transient receptor potential cation channel subfamily V member 1 antagonist transient receptor potential cation channel subfamily V member 1 antagonists vanilloid receptor 1 antagonist vanilloid receptor 1 antagonists ChEBI: TRPV1 antagonist ChEBI: vanilloid receptor 1 antagonists ChEBI: capsaicin antagonists ChEBI: TRPV1 antagonists ChEBI: capsaicin receptor antagonists ChEBI: transient receptor potential cation channel subfamily V member 1 antagonist ChEBI: capsaicin antagonist ChEBI: TrpV1 antagonists ChEBI: transient receptor potential cation channel subfamily V member 1 antagonists ChEBI: vanilloid receptor 1 antagonist Wikipedia Wikipedia:Discovery_and_development_of_TRPV1_antagonists ChEBI: TrpV1 antagonist PPAR modulator Any compound which acts on the peroxisome proliferator-activated receptor. CHEBI:70781 CiteXplore:18566691 CiteXplore:19746174 PPAR modulators Wikipedia:PPAR_modulator chebi_ontology peroxisome proliferator-activated receptor modulator peroxisome proliferator-activated receptor modulators PubMed citation CiteXplore:18566691 ChEBI: peroxisome proliferator-activated receptor modulator Wikipedia Wikipedia:PPAR_modulator ChEBI: peroxisome proliferator-activated receptor modulators PubMed citation CiteXplore:19746174 ChEBI: PPAR modulators PPARalpha agonist A PPAR modulator which activates the peroxisome proliferator-activated receptor-alpha. CHEBI:70782 PPAR-alpha agonist PPAR-alpha agonists PPARalpha agonist PPARalpha agonists chebi_ontology peroxisome proliferator-activated receptor-alpha agonist peroxisome proliferator-activated receptor-alpha agonists ChEBI: PPAR-alpha agonist ChEBI: PPARalpha agonist ChEBI: peroxisome proliferator-activated receptor-alpha agonists ChEBI: PPAR-alpha agonists ChEBI: PPARalpha agonists ChEBI: peroxisome proliferator-activated receptor-alpha agonist glyceraldehyde-3-phosphate dehydrogenase inhibitor An enzyme inhibitor that interferes with the action of glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) CHEBI:70817 GAPDH inhibitor GAPDH inhibitors Wikipedia:Glyceraldehyde-3-phosphate_dehydrogenase chebi_ontology glyceraldehyde-3-phosphate dehydrogenase inhibitors ChEBI: GAPDH inhibitors Wikipedia Wikipedia:Glyceraldehyde-3-phosphate_dehydrogenase ChEBI: glyceraldehyde-3-phosphate dehydrogenase inhibitors ChEBI: GAPDH inhibitor cathepsin L inhibitor A cysteine protease inhibitor which inhibits cathepsin L (EC 3.4.22.15). Aldrichina grahami cysteine proteinase inhibitor Aldrichina grahami cysteine proteinase inhibitors CHEBI:70821 EC 3.4.22.15 inhibitor EC 3.4.22.15 inhibitors cathepsin L inhibitors cathepsin L1 inhibitor cathepsin L1 inhibitors chebi_ontology ChEBI: EC 3.4.22.15 inhibitor ChEBI: cathepsin L1 inhibitor Aldrichina grahami cysteine proteinase inhibitors ChEBI: ChEBI: cathepsin L1 inhibitors Aldrichina grahami cysteine proteinase inhibitor ChEBI: ChEBI: EC 3.4.22.15 inhibitors ChEBI: cathepsin L inhibitors papain inhibitor A cysteine protease inhibitor which inhibits papain (EC 3.4.22.2). CHEBI:70822 EC 3.4.22.2 inhibitor EC 3.4.22.2 inhibitors chebi_ontology papain inhibitors papaine inhibitor papaine inhibitors papaya peptidase I inhibitor papaya peptidase I inhibitors papayotin inhibitor papayotin inhibitors summetrin inhibitor summetrin inhibitors velardon inhibitor velardon inhibitors ChEBI: papaine inhibitor ChEBI: papaine inhibitors ChEBI: EC 3.4.22.2 inhibitor ChEBI: papayotin inhibitors ChEBI: papaya peptidase I inhibitors ChEBI: EC 3.4.22.2 inhibitors ChEBI: summetrin inhibitor ChEBI: papaya peptidase I inhibitor ChEBI: velardon inhibitors ChEBI: papayotin inhibitor ChEBI: summetrin inhibitors ChEBI: papain inhibitors ChEBI: velardon inhibitor antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. CHEBI:70868 antileishmanial agents antileishmanial drug antileishmanial drugs chebi_ontology ChEBI: antileishmanial drugs ChEBI: antileishmanial drug ChEBI: antileishmanial agents reactive oxygen species generator Any entity used to generate reactive oxygen species. CHEBI:70982 ROS generator ROS generators chebi_ontology reactive oxygen species generators ChEBI: reactive oxygen species generators ChEBI: ROS generator ChEBI: ROS generators G-protein-coupled receptor agonist An agonist that binds to and activates G-protein-coupled receptors CHEBI:70998 G-protein-coupled receptor agonists GPCR agonist GPCR agonists Wikipedia:G_protein-coupled_receptor chebi_ontology ChEBI: GPCR agonists ChEBI: G-protein-coupled receptor agonists Wikipedia Wikipedia:G_protein-coupled_receptor ChEBI: GPCR agonist AMPA receptor antagonist AMPA receptor antagonists An antagonist at the AMPA receptor. CHEBI:71014 Wikipedia:AMPA_receptor alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists chebi_ontology AMPA receptor antagonists ChEBI: ChEBI: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist ChEBI: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists Wikipedia Wikipedia:AMPA_receptor progesterone receptor modulator A hormone receptor modulator that acts as a complete or partial agonist or as an antagonist at the progesterone receptor. CHEBI:71027 Wikipedia:Selective_progesterone_receptor_modulator chebi_ontology progesterone receptor modulators Wikipedia Wikipedia:Selective_progesterone_receptor_modulator ChEBI: progesterone receptor modulators orphan drug Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease. CHEBI:71031 CiteXplore:20036435 CiteXplore:20800761 CiteXplore:21180460 CiteXplore:21682893 CiteXplore:21947805 CiteXplore:22363762 CiteXplore:22366309 CiteXplore:22371464 CiteXplore:22731105 CiteXplore:22739138 CiteXplore:22747423 CiteXplore:22814659 CiteXplore:22814660 CiteXplore:22973866 CiteXplore:22981668 CiteXplore:22989856 CiteXplore:23013790 CiteXplore:23090701 CiteXplore:23109143 CiteXplore:23129684 Wikipedia:Orphan_drug chebi_ontology orphan drugs PubMed citation CiteXplore:21947805 PubMed citation CiteXplore:22731105 PubMed citation CiteXplore:22973866 PubMed citation CiteXplore:20800761 PubMed citation CiteXplore:23109143 PubMed citation CiteXplore:23013790 PubMed citation CiteXplore:22981668 PubMed citation CiteXplore:23090701 PubMed citation CiteXplore:21180460 Wikipedia Wikipedia:Orphan_drug ChEBI: orphan drugs PubMed citation CiteXplore:23129684 PubMed citation CiteXplore:22989856 PubMed citation CiteXplore:22371464 PubMed citation CiteXplore:22366309 PubMed citation CiteXplore:22739138 PubMed citation CiteXplore:22814659 PubMed citation CiteXplore:22747423 PubMed citation CiteXplore:22814660 PubMed citation CiteXplore:20036435 PubMed citation CiteXplore:22363762 PubMed citation CiteXplore:21682893 carbamylphosphate synthetase I activator An effector that binds and activates the enzyme carbamylphosphate synthetase I CHEBI:71033 Wikipedia:Carbamoyl_phosphate_synthetase_I carbamylphosphate synthetase I activators chebi_ontology ChEBI: carbamylphosphate synthetase I activators Wikipedia Wikipedia:Carbamoyl_phosphate_synthetase_I HIV-1 maturation inhibitor A compound that blocks the processing of the Gag precursor protein in HIV-1 by the viral protease enzyme, leading to the formation of noninfectious, immature virus particles that are incapable of infecting other cells. CHEBI:71168 HIV-1 maturation inhibitors Wikipedia:Maturation inhibitor chebi_ontology ChEBI: HIV-1 maturation inhibitors Wikipedia Wikipedia:Maturation inhibitor H1-receptor agonist A histamine agonist that binds to and activates H1-receptors. CHEBI:71173 H1-receptor agonists Wikipedia:Histamine_H1_receptor chebi_ontology histamine H1-receptor agonist histamine H1-receptor agonists ChEBI: H1-receptor agonists Wikipedia Wikipedia:Histamine_H1_receptor ChEBI: histamine H1-receptor agonist ChEBI: histamine H1-receptor agonists N-acetylserotonin methyltransferase inhibitor ASMT inhibitor ASMT inhibitors An enzyme inhibitor that interferes with the action of N-acetylserotonin methyltransferase (EC 2.1.1.4) CHEBI:71178 N-acetylserotonin methyltransferase inhibitors Wikipedia:Acetylserotonin_O-methyltransferase chebi_ontology Wikipedia Wikipedia:Acetylserotonin_O-methyltransferase ASMT inhibitor ChEBI: ASMT inhibitors ChEBI: ChEBI: N-acetylserotonin methyltransferase inhibitors Sir2 inhibitor An enzyme inhibitor that interferes with the action of Sir2. CHEBI:71181 Sir2 inhibitors Wikipedia:Sir2 chebi_ontology ChEBI: Sir2 inhibitors Wikipedia Wikipedia:Sir2 glucagon-like peptide-1 receptor agonist An agonist that binds to and activates glucagon-like peptide-1 (GLP-1) receptors. CHEBI:71196 GLP-1 receptor agonist GLP-1 receptor agonists Wikipedia:GLP-1_receptor chebi_ontology glucagon-like peptide-1 receptor agonists Wikipedia Wikipedia:GLP-1_receptor ChEBI: GLP-1 receptor agonists ChEBI: GLP-1 receptor agonist ChEBI: glucagon-like peptide-1 receptor agonists prohormone Any intra-glandular substance that acts as a precursor of a hormone, usually having minimal hormonal effect itself. Prohormones generally help in amplifying the effect of existing hormones. CHEBI:71212 Wikipedia:Prohormone chebi_ontology prohormones Wikipedia Wikipedia:Prohormone ChEBI: prohormones adenosine receptor antagonist An antagonist at any adenosine receptor. CHEBI:71232 Wikipedia:Adenosine_receptor adenosine receptor antagonists chebi_ontology Wikipedia Wikipedia:Adenosine_receptor ChEBI: adenosine receptor antagonists autoinducer A signalling molecule produced and used by bacteria participating in quorum sensing, that is, in cell-cell communication to coordinate community-wide regulation of processes such as biofilm formation, virulence, and bioluminescence in populations of bacteria. Such communication can occur both within and between different species of bacteria. CHEBI:71338 Wikipedia:Autoinducer autoinducers chebi_ontology ChEBI: autoinducers Wikipedia Wikipedia:Autoinducer fatty acid synthase inhibitor (FAS) inhibitors An enzyme inhibitor that inhibits the enzyme fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis. CHEBI:71476 chebi_ontology fatty acid synthase inhibitors (FAS) inhibitors ChEBI: ChEBI: fatty acid synthase inhibitors acid ceramidase inhibitor AC inhibitor AC inhibitors An enzyme inhibitor that interferes with the action of acid ceramidase. CHEBI:71551 N-acylsphingosine amidohydrolase inhibitor N-acylsphingosine amidohydrolase inhibitors acid ceramidase inhibitors chebi_ontology ChEBI: acid ceramidase inhibitors ChEBI: N-acylsphingosine amidohydrolase inhibitor AC inhibitors ChEBI: AC inhibitor ChEBI: ChEBI: N-acylsphingosine amidohydrolase inhibitors PPARgamma agonist A PPAR modulator which activates the peroxisome proliferator-activated receptor-gamma. CHEBI:71554 PPAR-gamma agonist PPAR-gamma agonists PPARgamma agonist PPARgamma agonists chebi_ontology peroxisome proliferator-activated receptor-gamma agonist peroxisome proliferator-activated receptor-gamma agonists ChEBI: PPAR-gamma agonist ChEBI: PPARgamma agonist ChEBI: PPAR-gamma agonists ChEBI: PPARgamma agonists ChEBI: peroxisome proliferator-activated receptor-gamma agonists ChEBI: peroxisome proliferator-activated receptor-gamma agonist insect repellent An insecticide that acts as a repellent to insects. CHEBI:71692 Wikipedia:Insect_repellent chebi_ontology insect repellents ChEBI: insect repellents Wikipedia Wikipedia:Insect_repellent phosphodiesterase V inhibitor A phosphodiesterase inhibitor that specifically blocks the action of phosphodiesterase V (EC 3.1.4.17). CHEBI:71942 CiteXplore:22996758 CiteXplore:23343170 CiteXplore:23346948 PDE5 inhibitor PDE5 inhibitors Wikipedia:CGMP-specific_phosphodiesterase_type_5 Wikipedia:PDE5_inhibitor chebi_ontology phosphodiesterase 5 inhibitor phosphodiesterase 5 inhibitors phosphodiesterase V inhibitors type 5 phosphodiesterase inhibitor type 5 phosphodiesterase inhibitors Wikipedia Wikipedia:PDE5_inhibitor ChEBI: type 5 phosphodiesterase inhibitors ChEBI: PDE5 inhibitor PubMed citation CiteXplore:22996758 PubMed citation CiteXplore:23343170 ChEBI: PDE5 inhibitors PubMed citation CiteXplore:23346948 ChEBI: phosphodiesterase 5 inhibitor Wikipedia Wikipedia:CGMP-specific_phosphodiesterase_type_5 ChEBI: phosphodiesterase V inhibitors ChEBI: phosphodiesterase 5 inhibitors ChEBI: type 5 phosphodiesterase inhibitor peptide deformylase inhibitor An enzyme inhibitor that interferes with the action of peptide deformylase (EC 3.5.1.88) involved in the catalytic removal of N-terminal formyl group of nascent proteins. CHEBI:71951 PDF inhibitors chebi_ontology peptide deformylase inhibitors ChEBI: peptide deformylase inhibitors ChEBI: PDF inhibitors nerve growth factor stimulator Any molecule shown to have the potentiality in stimulating the effect of nerve growth factor. CHEBI:72294 NGF stimulator NGF stimulators chebi_ontology nerve growth factor stimulators ChEBI: NGF stimulators ChEBI: nerve growth factor stimulators ChEBI: NGF stimulator MTP inhibitor An inhibitor that interferes with the action of MTP. CHEBI:72298 MTP inhibitors MTTP inhibitor MTTP inhibitors Wikipedia:Microsomal_triglyceride_transfer_protein chebi_ontology microsomal triglyceride transfer protein inhibitor microsomal triglyceride transfer protein inhibitors ChEBI: MTTP inhibitors Wikipedia Wikipedia:Microsomal_triglyceride_transfer_protein ChEBI: MTTP inhibitor ChEBI: microsomal triglyceride transfer protein inhibitors ChEBI: microsomal triglyceride transfer protein inhibitor ChEBI: MTP inhibitors glucagon-like peptide-2 receptor agonist An agonist that binds to and activates glucagon-like peptide-2 (GLP-2) receptors. CHEBI:72311 GLP-2 receptor agonist GLP-2 receptor agonists Wikipedia:Glucagon-like_peptide_2_receptor chebi_ontology glucagon-like peptide-2 receptor agonists Wikipedia Wikipedia:Glucagon-like_peptide_2_receptor ChEBI: GLP-2 receptor agonists ChEBI: GLP-2 receptor agonist ChEBI: glucagon-like peptide-2 receptor agonists virulence factor Any toxin secreted by bacteria, viruses, fungi or protozoa enabling them to achieve colonisation of a niche in the host, inhibit or evade the host's immune response, enter and exit cells, or obtain nutrition from the host. CHEBI:72316 CiteXplore:22851449 Wikipedia:Virulence_factor chebi_ontology virulence factors PubMed citation CiteXplore:22851449 ChEBI: virulence factors Wikipedia Wikipedia:Virulence_factor provitamin B1 A provitamin that can be converted into vitamin B1 by enzymes from animal tissues. CHEBI:72470 chebi_ontology provitamin B1s ChEBI: provitamin B1s vesicular glutamate transport inhibitor An inhibitor that interferes with vesicular glutamate transport. CHEBI:72483 Wikipedia:Vesicular_glutamate_transporter_1 chebi_ontology vesicular glutamate transport inhibitors vesicular glutamate transporter 1 inhibitor vesicular glutamate transporter 1 inhibitors Wikipedia Wikipedia:Vesicular_glutamate_transporter_1 ChEBI: vesicular glutamate transporter 1 inhibitor ChEBI: vesicular glutamate transporter 1 inhibitors ChEBI: vesicular glutamate transport inhibitors pro-angiogenic agent Any compound that promotes the growth of new blood vessels from pre-existing vessels. CHEBI:72571 chebi_ontology pro-angiogenic agents proangiogenic agent proangiogenic agents ChEBI: pro-angiogenic agents ChEBI: proangiogenic agents ChEBI: proangiogenic agent alarm pheromone A pheromone which is released by an organism when damaged by a predator which warns other individuals that there is a danger. CHEBI:72575 CiteXplore:20831948 CiteXplore:22870255 alarm pheromones alarm signal alarm signals alarm substance alarm substances chebi_ontology PubMed citation CiteXplore:20831948 ChEBI: alarm substances ChEBI: alarm signals ChEBI: alarm signal ChEBI: alarm substance ChEBI: alarm pheromones PubMed citation CiteXplore:22870255 transglutaminase-2 inhibitor An enzyme inhibitor that interferes with the action of transglutaminase-2 (EC 2.3.2.13). CHEBI:72716 TG-2 inhibitor TG-2 inhibitors TG2 inhibitor TG2 inhibitors Wikipedia:Transglutaminase chebi_ontology transglutaminase-2 inhibitors ChEBI: TG-2 inhibitor Wikipedia Wikipedia:Transglutaminase ChEBI: TG-2 inhibitors ChEBI: transglutaminase-2 inhibitors ChEBI: TG2 inhibitor ChEBI: TG2 inhibitors aryl hydrocarbon receptor agonist AHR agonist AHR agonists AhR agonist AhR agonists An agonist that binds to and activates aryl hydrocarbon receptors (AhRs). CHEBI:72768 aryl hydrocarbon receptor agonists chebi_ontology ChEBI: aryl hydrocarbon receptor agonists AhR agonists ChEBI: AhR agonist ChEBI: AHR agonist ChEBI: AHR agonists ChEBI: breast cancer resistance protein inhibitor ABCG2 inhibitor ABCG2 inhibitors Any inhibitor of breast cancer resistance protein (ABCG2). CHEBI:72771 Wikipedia:ABCG2 breast cancer resistance protein inhibitors chebi_ontology ABCG2 inhibitor ChEBI: ChEBI: breast cancer resistance protein inhibitors Wikipedia Wikipedia:ABCG2 ABCG2 inhibitors ChEBI: carotogenesis inhibitor Any inhibitor of the biosynthesis of carotenoids. CHEBI:72773 carotogenesis inhibitors chebi_ontology ChEBI: carotogenesis inhibitors phytoene dehydrogenase inhibitor Any compound that inhibits the action of phytoene dehydrogenase (phytoene desaturase), an enzyme of carotenoid biosynthesis that converts phytoene into zeta-carotene (zeta-carotene) via the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene. CHEBI:72774 chebi_ontology phytoene dehydrogenase inhibitors phytoene desaturase inhibitor phytoene desaturase inhibitors ChEBI: phytoene desaturase inhibitor ChEBI: phytoene dehydrogenase inhibitors ChEBI: phytoene desaturase inhibitors indoleamine 2,3-dioxygenase inhibitor An enzyme inhibitor that interferes with the action of indoleamine 2,3-dioxygenase (EC 1.13.11.52). CHEBI:72854 IDO inhibitor IDO inhibitors Wikipedia:Indoleamine_2,3-dioxygenase chebi_ontology indoleamine 2,3-dioxygenase inhibitors Wikipedia Wikipedia:Indoleamine_2,3-dioxygenase ChEBI: indoleamine 2,3-dioxygenase inhibitors ChEBI: IDO inhibitors ChEBI: IDO inhibitor carbonyl reductase (NADPH) inhibitor ALR3 inhibitor ALR3 inhibitors An enzyme inhibitor that inhibits the action of EC 1.1.1.184, carbonyl reductase (NADPH). CHEBI:73136 EC 1.1.1.184 inhibitor EC 1.1.1.184 inhibitors NADPH2-dependent carbonyl reductase inhibitor NADPH2-dependent carbonyl reductase inhibitors Wikipedia:Carbonyl_reductase_(NADPH) aldehyde reductase 1 inhibitor aldehyde reductase 1 inhibitors carbonyl reductase (NADPH) inhibitors carbonyl reductase (NADPH2) inhibitor carbonyl reductase (NADPH2) inhibitors carbonyl reductase inhibitor carbonyl reductase inhibitors chebi_ontology nonspecific NADPH-dependent carbonyl reductase inhibitor nonspecific NADPH-dependent carbonyl reductase inhibitors prostaglandin 9-ketoreductase inhibitor prostaglandin 9-ketoreductase inhibitors secondary-alcohol:NADP+ oxidoreductase inhibitor secondary-alcohol:NADP+ oxidoreductase inhibitors xenobiotic ketone reductase inhibitor xenobiotic ketone reductase inhibitors ChEBI: prostaglandin 9-ketoreductase inhibitors ChEBI: carbonyl reductase inhibitors ChEBI: EC 1.1.1.184 inhibitor ChEBI: aldehyde reductase 1 inhibitor Wikipedia Wikipedia:Carbonyl_reductase_(NADPH) ChEBI: NADPH2-dependent carbonyl reductase inhibitor ALR3 inhibitor ChEBI: ChEBI: carbonyl reductase (NADPH2) inhibitors ChEBI: carbonyl reductase (NADPH2) inhibitor ChEBI: carbonyl reductase inhibitor ALR3 inhibitors ChEBI: ChEBI: secondary-alcohol:NADP+ oxidoreductase inhibitors ChEBI: xenobiotic ketone reductase inhibitors ChEBI: nonspecific NADPH-dependent carbonyl reductase inhibitor ChEBI: carbonyl reductase (NADPH) inhibitors ChEBI: nonspecific NADPH-dependent carbonyl reductase inhibitors ChEBI: aldehyde reductase 1 inhibitors ChEBI: NADPH2-dependent carbonyl reductase inhibitors ChEBI: xenobiotic ketone reductase inhibitor ChEBI: prostaglandin 9-ketoreductase inhibitor ChEBI: secondary-alcohol:NADP+ oxidoreductase inhibitor ChEBI: EC 1.1.1.184 inhibitors L-ascorbate peroxidase inhibitor An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of L-ascorbate peroxidase, EC 1.11.1.11. CHEBI:73181 EC 1.11.1.11 inhibitor EC 1.11.1.11 inhibitors L-ascorbate peroxidase inhibitor L-ascorbate peroxidase inhibitors L-ascorbate:hydrogen-peroxide oxidoreductase inhibitor L-ascorbate:hydrogen-peroxide oxidoreductase inhibitors L-ascorbic acid peroxidase inhibitor L-ascorbic acid peroxidase inhibitors L-ascorbic acid-specific peroxidase inhibitor L-ascorbic acid-specific peroxidase inhibitors Wikipedia:L-ascorbate_peroxidase ascorbate peroxidase inhibitor ascorbate peroxidase inhibitors ascorbic acid peroxidase inhibitor ascorbic acid peroxidase inhibitors chebi_ontology ChEBI: L-ascorbic acid-specific peroxidase inhibitor ChEBI: ascorbic acid peroxidase inhibitor ChEBI: EC 1.11.1.11 inhibitors ChEBI: L-ascorbic acid-specific peroxidase inhibitors ChEBI: L-ascorbic acid peroxidase inhibitors ChEBI: L-ascorbate:hydrogen-peroxide oxidoreductase inhibitor ChEBI: L-ascorbic acid peroxidase inhibitor Wikipedia Wikipedia:L-ascorbate_peroxidase ChEBI: L-ascorbate:hydrogen-peroxide oxidoreductase inhibitors ChEBI: ascorbate peroxidase inhibitors ChEBI: ascorbate peroxidase inhibitor ChEBI: ascorbic acid peroxidase inhibitors ChEBI: L-ascorbate peroxidase inhibitor ChEBI: L-ascorbate peroxidase inhibitors ChEBI: EC 1.11.1.11 inhibitor plant activator Any compound that protects plants by activating their defence mechanisms. CHEBI:73182 chebi_ontology plant activators ChEBI: plant activators brassinosteroid biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of brassinosteroids. CHEBI:73189 CiteXplore:10462767 brassinosteroid biosynthesis inhibitors chebi_ontology PubMed citation CiteXplore:10462767 ChEBI: brassinosteroid biosynthesis inhibitors antimutagen An agent that reduces or interferes with the mutagenic actions or effects of a substance. CHEBI:73190 antimutagenic agent antimutagenic agents antimutagens chebi_ontology ChEBI: antimutagenic agents ChEBI: antimutagenic agent ChEBI: antimutagens abscisic acid receptor agonist ABA agonist ABA agonists ABA receptor agonist ABA receptor agonists An agonist that binds to and activates abscisic acid receptors. CHEBI:73191 abscisic acid receptor agonists chebi_ontology ChEBI: abscisic acid receptor agonists ABA agonist ChEBI: ABA receptor agonists ChEBI: ABA receptor agonist ChEBI: ABA agonists ChEBI: protoporphyrinogen oxidase inhibitor An enzyme inhibitor that inhibits the action of protoporphyrinogen oxidase, EC 1.3.3.4. CHEBI:73192 CiteXplore:15660355 CiteXplore:22273380 EC 1.3.3.4 inhibitor EC 1.3.3.4 inhibitors HemG inhibitor HemG inhibitors HemY inhibitor HemY inhibitors PPO inhibitor PPO inhibitors Protox inhibitor Protox inhibitors Wikipedia:Protoporphyrinogen_oxidase chebi_ontology protoporphyrinogen IX oxidase inhibitor protoporphyrinogen IX oxidase inhibitors protoporphyrinogen oxidase inhibitors protoporphyrinogen-IX:oxygen oxidoreductase inhibitor protoporphyrinogen-IX:oxygen oxidoreductase inhibitors protoporphyrinogenase inhibitor protoporphyrinogenase inhibitors ChEBI: PPO inhibitors ChEBI: HemY inhibitors ChEBI: PPO inhibitor ChEBI: EC 1.3.3.4 inhibitors ChEBI: Protox inhibitor ChEBI: protoporphyrinogen-IX:oxygen oxidoreductase inhibitors ChEBI: protoporphyrinogenase inhibitors ChEBI: HemG inhibitor ChEBI: HemY inhibitor ChEBI: EC 1.3.3.4 inhibitor ChEBI: protoporphyrinogen IX oxidase inhibitors PubMed citation CiteXplore:22273380 Wikipedia Wikipedia:Protoporphyrinogen_oxidase ChEBI: protoporphyrinogenase inhibitor ChEBI: protoporphyrinogen-IX:oxygen oxidoreductase inhibitor ChEBI: protoporphyrinogen IX oxidase inhibitor ChEBI: HemG inhibitors ChEBI: Protox inhibitors ChEBI: protoporphyrinogen oxidase inhibitors PubMed citation CiteXplore:15660355 gibberellin biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of gibberellins. CHEBI:73193 chebi_ontology gibberellin biosynthesis inhibitors ChEBI: gibberellin biosynthesis inhibitors methionine gamma-lyase inhibitor An enzyme inhibitor that interferes with the action of the enzyme methionine gamma-lyase (EC 4.4.1.11). CHEBI:73196 L-methioninase inhibitor L-methioninase inhibitors Wikipedia:Methionine_gamma-lyase chebi_ontology methioninase inhibitor methioninase inhibitors methionine gamma-lyase inhibitors ChEBI: L-methioninase inhibitors ChEBI: methioninase inhibitors Wikipedia Wikipedia:Methionine_gamma-lyase ChEBI: methionine gamma-lyase inhibitors ChEBI: methioninase inhibitor ChEBI: L-methioninase inhibitor H(+)-transporting two-sector ATPase inhibitor ATP phosphohydrolase (H(+)-transporting) inhibitor ATP phosphohydrolase (H(+)-transporting) inhibitors ATP synthase inhibitor ATP synthase inhibitors Any acid anhydride hydrolase inhibitor that inhibits the action of H(+)-transporting two-sector ATPase inhibitor, EC 3.6.3.14. CHEBI:73214 EC 3.6.3.14 inhibitor EC 3.6.3.14 inhibitors F1-ATPase inhibitor F1-ATPase inhibitors FoF1-ATPase inhibitor FoF1-ATPase inhibitors H(+)-transporting ATPase inhibitor H(+)-transporting ATPase inhibitors H(+)-transporting two-sector ATPase inhibitors Wikipedia:ATP_synthase bacterial Ca(2+)/Mg(2+) ATPase inhibitor bacterial Ca(2+)/Mg(2+) ATPase inhibitors chebi_ontology chloroplast ATPase inhibitor chloroplast ATPase inhibitors coupling factors (Fo, F1 and CF1) inhibitor coupling factors (Fo, F1 and CF1) inhibitors mitochondrial ATPase inhibitor mitochondrial ATPase inhibitors ChEBI: bacterial Ca(2+)/Mg(2+) ATPase inhibitors ChEBI: chloroplast ATPase inhibitor ChEBI: bacterial Ca(2+)/Mg(2+) ATPase inhibitor ChEBI: EC 3.6.3.14 inhibitor ChEBI: H(+)-transporting ATPase inhibitors ChEBI: chloroplast ATPase inhibitors ChEBI: coupling factors (Fo, F1 and CF1) inhibitors ChEBI: mitochondrial ATPase inhibitors ChEBI: FoF1-ATPase inhibitor ChEBI: mitochondrial ATPase inhibitor ChEBI: H(+)-transporting ATPase inhibitor ChEBI: FoF1-ATPase inhibitors ChEBI: EC 3.6.3.14 inhibitors ChEBI: F1-ATPase inhibitor ATP synthase inhibitor ChEBI: ChEBI: H(+)-transporting two-sector ATPase inhibitors ATP phosphohydrolase (H(+)-transporting) inhibitor ChEBI: Wikipedia Wikipedia:ATP_synthase ATP phosphohydrolase (H(+)-transporting) inhibitors ChEBI: ATP synthase inhibitors ChEBI: ChEBI: F1-ATPase inhibitors ChEBI: coupling factors (Fo, F1 and CF1) inhibitor acid anhydride hydrolase inhibitor An enzyme inhibitor that inhibits the action of any hydrolase that acts on an acid anhydride (EC 3.6.*.*). CHEBI:73216 EC 3.6 inhibitor EC 3.6 inhibitors EC 3.6.* inhibitor EC 3.6.* inhibitors EC 3.6.*.* inhibitor EC 3.6.*.* inhibitors acid anhydride hydrolase inhibitors chebi_ontology ChEBI: EC 3.6 inhibitor ChEBI: acid anhydride hydrolase inhibitors ChEBI: EC 3.6.* inhibitors ChEBI: EC 3.6 inhibitors ChEBI: EC 3.6.* inhibitor ChEBI: EC 3.6.*.* inhibitors ChEBI: EC 3.6.*.* inhibitor NF-kappaB inhibitor An inhibitor of NF-kappaB (nuclear factor kappa-light-chain-enhancer of activated B cells), a protein complex involved in the transcription of DNA. CHEBI:73240 NF-kappaB inhibitors Wikipedia:NF-%CE%BAB chebi_ontology nuclear factor kappa-light-chain-enhancer of activated B cells inhibitor nuclear factor kappa-light-chain-enhancer of activated B cells inhibitors Wikipedia Wikipedia:NF-%CE%BAB ChEBI: NF-kappaB inhibitors ChEBI: nuclear factor kappa-light-chain-enhancer of activated B cells inhibitor ChEBI: nuclear factor kappa-light-chain-enhancer of activated B cells inhibitors cyclooxygenase 3 inhibitor A cyclooxygenase inhibitor with specificity for cyclooxygenase 3. CHEBI:73263 COX-3 inhibitor COX-3 inhibitors CiteXplore:12242329 CiteXplore:12374850 CiteXplore:14592546 Wikipedia:COX-3 chebi_ontology cyclo-oxygenase 3 inhibitor cyclo-oxygenase 3 inhibitors cyclooxygenase 3 inhibitors cyclooxygenase-3 inhibitor cyclooxygenase-3 inhibitors ChEBI: cyclo-oxygenase 3 inhibitor COX-3 inhibitor ChEBI: PubMed citation CiteXplore:12242329 PubMed citation CiteXplore:12374850 Wikipedia Wikipedia:COX-3 ChEBI: cyclo-oxygenase 3 inhibitors ChEBI: cyclooxygenase-3 inhibitors ChEBI: cyclooxygenase-3 inhibitor COX-3 inhibitors ChEBI: PubMed citation CiteXplore:14592546 ChEBI: cyclooxygenase 3 inhibitors oxidative phosphorylation inhibitor Any compound that inhibits oxidative phosphorylation. CHEBI:73267 chebi_ontology oxidative phosphorylation inhibitors ChEBI: oxidative phosphorylation inhibitors sodium-glucose transport protein subtype 2 inhibitor An inhibitor that interferes with the action of sodium-glucose transport protein subtype 2. CHEBI:73273 SGLT2 inhibitor SGLT2 inhibitors Wikipedia:SLC5A2 chebi_ontology sodium glucose co-transporter 2 inhibitor sodium glucose co-transporter 2 inhibitors sodium-glucose transport protein subtype 2 inhibitors Wikipedia Wikipedia:SLC5A2 ChEBI: sodium glucose co-transporter 2 inhibitor ChEBI: sodium-glucose transport protein subtype 2 inhibitors ChEBI: sodium glucose co-transporter 2 inhibitors ChEBI: SGLT2 inhibitors ChEBI: SGLT2 inhibitor cholecystokinin antagonist A hormone antagonist that inhibits the action of the peptide hormone cholecystokinin. CCK antagonist CCK antagonists CHEBI:73296 Wikipedia:Cholecystokinin_antagonist chebi_ontology cholecystokinin antagonists CCK antagonist ChEBI: CCK antagonists ChEBI: ChEBI: cholecystokinin antagonists Wikipedia Wikipedia:Cholecystokinin_antagonist adenosine A2A receptor agonist A2A agonist A2A agonists A2A receptor agonist A2A receptor agonists An agonist at the A2A receptor. CHEBI:73310 Wikipedia:Adenosine_A2A_receptor adenosine A2A receptor agonists chebi_ontology ChEBI: adenosine A2A receptor agonists A2A receptor agonist ChEBI: A2A receptor agonists ChEBI: A2A agonists ChEBI: Wikipedia Wikipedia:Adenosine_A2A_receptor A2A agonist ChEBI: adenosine receptor agonist An agonist at any adenosine receptor. CHEBI:73311 adenosine receptor agonist chebi_ontology ChEBI: adenosine receptor agonist adenosine A3 receptor agonist A3 agonist A3 agonists A3 receptor agonist A3 receptor agonists An agonist at the adenosine A3 receptor. CHEBI:73319 Wikipedia:Adenosine_A3_receptor adenosine A3 receptor agonists chebi_ontology A3 receptor agonist ChEBI: A3 agonists ChEBI: A3 receptor agonists ChEBI: A3 agonist ChEBI: ChEBI: adenosine A3 receptor agonists Wikipedia Wikipedia:Adenosine_A3_receptor scabicide An acaricide that kills mites of the genus Sarcoptes. CHEBI:73333 Wikipedia:Scabicide chebi_ontology scabicides ChEBI: scabicides Wikipedia Wikipedia:Scabicide thyroid hormone agonist A hormone agonist that binds to and activates a thyroid hormone receptor. CHEBI:73334 Wikipedia:Thyroid_hormone_receptor chebi_ontology thyroid hormone agonists thyromimetic thyromimetics SUBMITTER: thyromimetic ChEBI: thyroid hormone agonists ChEBI: thyromimetics Wikipedia Wikipedia:Thyroid_hormone_receptor ultraviolet filter A photochemical role realized in the absorption of ultraviolet light, for example to protect skin cells from damage. CHEBI:73335 UV filter UV filters Wikipedia:UV_filter chebi_ontology ultraviolet filters ChEBI: UV filter ChEBI: UV filters Wikipedia Wikipedia:UV_filter ChEBI: ultraviolet filters vulnerary A drug used in treating and healing of wounds. CHEBI:73336 Wikipedia:Wound_healing chebi_ontology vulneraries wound-healing agent wound-healing agents wound-healing drug wound-healing drugs ChEBI: wound-healing drugs ChEBI: wound-healing agents Wikipedia Wikipedia:Wound_healing ChEBI: wound-healing drug ChEBI: vulneraries ChEBI: wound-healing agent protein-sequencing agent Any agent used to determine the amino-acid sequence in a polypeptide. CHEBI:73352 chebi_ontology protein-sequencing agents sequencing agent sequencing agents ChEBI: sequencing agent ChEBI: protein-sequencing agents ChEBI: sequencing agents creatine kinase inhibitor An enzyme inhibitor that inhibits the action of creatine kinase, EC 2.7.3.2. CHEBI:73354 CK inhibitor CK inhibitors CPK inhibitor CPK inhibitors chebi_ontology creatine kinase inhibitors creatine phosphokinase inhibitor creatine phosphokinase inhibitors ChEBI: creatine phosphokinase inhibitor CK inhibitors ChEBI: CK inhibitor ChEBI: CPK inhibitors ChEBI: ChEBI: creatine kinase inhibitors ChEBI: creatine phosphokinase inhibitors CPK inhibitor ChEBI: methionyl aminopeptidase inhibitor Any enzyme inhibitor that inhibits the action of methionyl aminopeptidase (EC 3.4.11.18). CHEBI:73360 EC 3.4.11.18 inhibitor EC 3.4.11.18 inhibitors L-methionine aminopeptidase inhibitor L-methionine aminopeptidase inhibitors MAP inhibitor MAP inhibitors Wikipedia:Methionyl_aminopeptidase chebi_ontology methionine aminopeptidase inhibitor methionine aminopeptidase inhibitors methionyl aminopeptidase inhibitors peptidase M inhibitor peptidase M inhibitors Wikipedia Wikipedia:Methionyl_aminopeptidase ChEBI: methionine aminopeptidase inhibitors ChEBI: peptidase M inhibitor ChEBI: MAP inhibitors ChEBI: L-methionine aminopeptidase inhibitor ChEBI: MAP inhibitor ChEBI: EC 3.4.11.18 inhibitor ChEBI: L-methionine aminopeptidase inhibitors ChEBI: EC 3.4.11.18 inhibitors ChEBI: methionyl aminopeptidase inhibitors ChEBI: methionine aminopeptidase inhibitor ChEBI: peptidase M inhibitors methionine aminopeptidase 2 inhibitor Any methionyl aminopeptidase inhibitor that inhibits the action of methionyl aminopeptidase 2. CHEBI:73361 MAP2 inhibitor MAP2 inhibitors METAP2 inhibitor METAP2 inhibitors MetAP2 inhibitor MetAP2 inhibitors Wikipedia:METAP2 chebi_ontology methionine aminopeptidase 2 inhibitors methionine aminopeptidase-2 inhibitor methionine aminopeptidase-2 inhibitors ChEBI: MAP2 inhibitors ChEBI: methionine aminopeptidase-2 inhibitor ChEBI: METAP2 inhibitors ChEBI: MetAP2 inhibitors Wikipedia Wikipedia:METAP2 ChEBI: methionine aminopeptidase-2 inhibitors ChEBI: MAP2 inhibitor ChEBI: MetAP2 inhibitor ChEBI: methionine aminopeptidase 2 inhibitors ChEBI: METAP2 inhibitor cannabinoid receptor antagonist An antagonist that binds to and deactivates cannabinoid receptors. CHEBI:73413 Wikipedia:Cannabinoid_receptor cannabinoid receptor antagonists chebi_ontology ChEBI: cannabinoid receptor antagonists Wikipedia Wikipedia:Cannabinoid_receptor CB1 receptor antagonist An antagonist that binds to and deactivates type 1 cannabinoid receptors. CB1 receptor antagonist CB1 receptor antagonists CB1R antagonist CB1R antagonists CHEBI:73416 CiteXplore:22463610 Wikipedia:Cannabinoid_receptor_type_1 cannabinoid receptor type 1 antagonist cannabinoid receptor type 1 antagonists chebi_ontology type 1 cannabinoid receptor antagonist type 1 cannabinoid receptor antagonists ChEBI: type 1 cannabinoid receptor antagonist CB1R antagonist ChEBI: CB1R antagonists ChEBI: ChEBI: cannabinoid receptor type 1 antagonist ChEBI: cannabinoid receptor type 1 antagonists Wikipedia Wikipedia:Cannabinoid_receptor_type_1 PubMed citation CiteXplore:22463610 CB1 receptor antagonists ChEBI: ChEBI: type 1 cannabinoid receptor antagonists CB1 receptor antagonist ChEBI: CB2 receptor antagonist An antagonist that binds to and deactivates type 2 cannabinoid receptors. CB2 receptor antagonist CB2 receptor antagonists CB2R antagonist CB2R antagonists CHEBI:73417 Wikipedia:Cannabinoid_receptor_type_2 cannabinoid receptor type 2 antagonist cannabinoid receptor type 2 antagonists chebi_ontology type 2 cannabinoid receptor antagonist type 2 cannabinoid receptor antagonists Wikipedia Wikipedia:Cannabinoid_receptor_type_2 CB2R antagonist ChEBI: ChEBI: type 2 cannabinoid receptor antagonist ChEBI: cannabinoid receptor type 2 antagonist CB2 receptor antagonists ChEBI: CB2 receptor antagonist ChEBI: CB2R antagonists ChEBI: ChEBI: type 2 cannabinoid receptor antagonists ChEBI: cannabinoid receptor type 2 antagonists spectrophotometric reagent A reagent used in the determination by spectrophotometry of the concentration of a chemical element or chemical compound in solution. CHEBI:73618 chebi_ontology spectrophotometric reagents ChEBI: spectrophotometric reagents tolerogen A substance that invokes a specific immune non-responsiveness due to its molecular form. If its molecular form is changed, a tolerogen can become an immunogen. CHEBI:73623 chebi_ontology tolerogens ChEBI: tolerogens peptide coupling reagent A reagent used to couple amino acids during artificial peptide synthesis. CHEBI:73668 chebi_ontology peptide coupling reagents ChEBI: peptide coupling reagents PPARbeta/delta agonist A PPAR modulator which activates the peroxisome proliferator-activated receptor-beta/delta. CHEBI:73729 CHEBI:73730 NR1C2 agonist NR1C2 agonists PPAR(beta/delta) agonist PPAR(beta/delta) agonists PPAR-beta agonist PPAR-beta agonists PPAR-beta/delta agonist PPAR-beta/delta agonists PPAR-delta agonist PPAR-delta agonists PPARD agonist PPARD agonists PPARD receptor agonist PPARD receptor agonists PPARbeta agonist PPARbeta agonists PPARbeta/delta agonist PPARbeta/delta agonists PPARdelta agonist PPARdelta agonists Wikipedia:Peroxisome_proliferator-activated_receptor_delta chebi_ontology nuclear receptor subfamily 1, group C, member 2 agonist nuclear receptor subfamily 1, group C, member 2 agonists peroxisome proliferator-activated receptor-beta agonist peroxisome proliferator-activated receptor-beta agonists peroxisome proliferator-activated receptor-delta agonist peroxisome proliferator-activated receptor-delta agonists ChEBI: PPARD agonists ChEBI: peroxisome proliferator-activated receptor-beta agonists ChEBI: PPARbeta agonists ChEBI: PPARbeta/delta agonist ChEBI: peroxisome proliferator-activated receptor-beta agonist ChEBI: peroxisome proliferator-activated receptor-delta agonists ChEBI: PPARD receptor agonist ChEBI: PPARD agonist ChEBI: PPAR-delta agonist ChEBI: PPAR(beta/delta) agonist ChEBI: PPAR-beta/delta agonists ChEBI: PPAR-delta agonists ChEBI: nuclear receptor subfamily 1, group C, member 2 agonists ChEBI: peroxisome proliferator-activated receptor-delta agonist ChEBI: PPAR-beta/delta agonist ChEBI: PPARbeta agonist ChEBI: NR1C2 agonists ChEBI: nuclear receptor subfamily 1, group C, member 2 agonist ChEBI: PPAR-beta agonist ChEBI: PPAR-beta agonists Wikipedia Wikipedia:Peroxisome_proliferator-activated_receptor_delta ChEBI: PPARbeta/delta agonists ChEBI: PPARdelta agonists ChEBI: PPARdelta agonist ChEBI: PPAR(beta/delta) agonists ChEBI: NR1C2 agonist ChEBI: PPARD receptor agonists vibriostatic agent Any compound that inhibits the growth of bacteria of the genus Vibrio. CHEBI:73911 chebi_ontology vibriostatic vibriostatics ChEBI: vibriostatic ChEBI: vibriostatics antifolate An antimetabolite that impairs the action of folic acids CHEBI:73913 Wikipedia:Antifolate antifolates chebi_ontology folic acid antagonist folic acid antagonists ChEBI: antifolates ChEBI: folic acid antagonist ChEBI: folic acid antagonists Wikipedia Wikipedia:Antifolate nitric oxide synthase activator An effector that binds to and activates the enzyme nitric oxide synthase (EC 1.14.13.39) CHEBI:73966 NOS inhibitor NOS inhibitors Wikipedia:Nitric_oxide_synthase chebi_ontology nitric oxide synthase activators Wikipedia Wikipedia:Nitric_oxide_synthase ChEBI: NOS inhibitor ChEBI: NOS inhibitors ChEBI: nitric oxide synthase activators lachrymator Any substance that stimulates the corneal nerves in the eves to cause tears. CHEBI:74136 CiteXplore:4919431 chebi_ontology lachrymators PubMed citation CiteXplore:4919431 ChEBI: lachrymators mordant CHEBI:74152 Substance used to set dyes on fabrics or tissue sections by forming a coordination complex with the dye which then attaches to the fabric or tissue. Wikipedia:Mordant chebi_ontology Wikipedia Wikipedia:Mordant ribonucleoside-diphosphate reductase inhibitor 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitor 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitors ADP reductase inhibitor ADP reductase inhibitors An enzyme inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1). CDP reductase inhibitor CDP reductase inhibitors CHEBI:74213 EC 1.17.4.1 inhibitor EC 1.17.4.1 inhibitors RR inhibitor RR inhibitors UDP reductase inhibitor UDP reductase inhibitors Wikipedia:Ribonucleoside-diphosphate_reductase chebi_ontology nucleoside diphosphate reductase inhibitor nucleoside diphosphate reductase inhibitors ribonucleoside diphosphate reductase inhibitor ribonucleoside diphosphate reductase inhibitors ribonucleoside-diphosphate reductase inhibitors ribonucleotide diphosphate reductase inhibitor ribonucleotide diphosphate reductase inhibitors ribonucleotide reductase inhibitor ribonucleotide reductase inhibitors ChEBI: ribonucleoside diphosphate reductase inhibitors ChEBI: ribonucleotide diphosphate reductase inhibitors ADP reductase inhibitors ChEBI: ChEBI: ribonucleotide diphosphate reductase inhibitor ChEBI: RR inhibitors ChEBI: ribonucleotide reductase inhibitor ChEBI: nucleoside diphosphate reductase inhibitors ChEBI: UDP reductase inhibitors ChEBI: EC 1.17.4.1 inhibitor ADP reductase inhibitor ChEBI: ChEBI: ribonucleoside-diphosphate reductase inhibitors CDP reductase inhibitors ChEBI: ChEBI: ribonucleotide reductase inhibitors ChEBI: EC 1.17.4.1 inhibitors Wikipedia Wikipedia:Ribonucleoside-diphosphate_reductase ChEBI: ribonucleoside diphosphate reductase inhibitor ChEBI: nucleoside diphosphate reductase inhibitor 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitors ChEBI: CDP reductase inhibitor ChEBI: 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitor ChEBI: ChEBI: RR inhibitor ChEBI: UDP reductase inhibitor sepiapterin reductase inhibitor 7,8-dihydrobiopterin:NADP(+) oxidoreductase 7,8-dihydrobiopterin:NADP(+) oxidoreductases An enzyme inhibitor that interferes with the activity of sepiapterin reductase (EC 1.1.1.153), which plays an important part in the biosynthesis of tetrahydrobiopterin. CHEBI:74234 Wikipedia:Sepiapterin_reductase chebi_ontology sepiapterin reductase inhibitors ChEBI: sepiapterin reductase inhibitors Wikipedia Wikipedia:Sepiapterin_reductase 7,8-dihydrobiopterin:NADP(+) oxidoreductase ChEBI: 7,8-dihydrobiopterin:NADP(+) oxidoreductases ChEBI: polymerisation monomer Any compound used as a monomer for a polymerisation process. The term is generally used in relation to industrial polymerisation processes. CHEBI:74236 chebi_ontology polymerization monomer ChEBI: polymerization monomer quinol oxidation site inhibitor An compound that inhibits quinol oxidation sites. CHEBI:74352 CiteXplore:15312779 CiteXplore:7961852 QP site inhibitor QP site inhibitors chebi_ontology quinol oxidation site inhibitors PubMed citation CiteXplore:15312779 ChEBI: quinol oxidation site inhibitors ChEBI: QP site inhibitors ChEBI: QP site inhibitor PubMed citation CiteXplore:7961852 epidermal growth factor receptor antagonist An antagonist at the epidermal growth factor receptor. CHEBI:74440 EGFR antagonoist EGFR antagonoists EGFR inhibitor EGFR inhibitors Wikipedia:Epidermal_growth_factor_receptor chebi_ontology epidermal growth factor receptor antagonists epidermal growth factor receptor inhibitor epidermal growth factor receptor inhibitors ChEBI: epidermal growth factor receptor inhibitors Wikipedia Wikipedia:Epidermal_growth_factor_receptor ChEBI: EGFR inhibitors ChEBI: EGFR antagonoist ChEBI: EGFR antagonoists ChEBI: epidermal growth factor receptor inhibitor ChEBI: epidermal growth factor receptor antagonists ChEBI: EGFR inhibitor anti-obesity agent Any substance which is used to reduce or control weight. CHEBI:74518 Wikipedia:Anti-obesity anti-obesity agents anti-obestic agent anti-obestic agents chebi_ontology ChEBI: anti-obestic agent Wikipedia Wikipedia:Anti-obesity ChEBI: anti-obestic agents ChEBI: anti-obesity agents NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase inhibitor 6-phospho-D-gluconate dehydrogenase inhibitor 6-phospho-D-gluconate dehydrogenase inhibitors 6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) inhibitor 6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) inhibitors 6-phosphogluconate dehydrogenase (decarboxylating) inhibitor 6-phosphogluconate dehydrogenase (decarboxylating) inhibitors 6-phosphogluconic carboxylase inhibitor 6-phosphogluconic carboxylase inhibitors 6-phosphogluconic dehydrogenase inhibitor 6-phosphogluconic dehydrogenase inhibitors An enzyme inhibitor that interferes with the action of NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase (EC 1.1.1.44). CHEBI:74520 EC 1.1.1.44 inhibitor EC 1.1.1.44 inhibitors NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase inhibitors Wikipedia:Phosphogluconate_dehydrogenase_(decarboxylating) chebi_ontology phosphogluconate dehydrogenase (NADP+ -dependent, decarboxylating) inhibitor phosphogluconate dehydrogenase (NADP+ -dependent, decarboxylating) inhibitors phosphogluconic acid dehydrogenase inhibitor phosphogluconic acid dehydrogenase inhibitors ChEBI: phosphogluconic acid dehydrogenase inhibitors ChEBI: EC 1.1.1.44 inhibitors 6-phosphogluconic carboxylase inhibitor ChEBI: 6-phosphogluconate dehydrogenase (decarboxylating) inhibitors ChEBI: ChEBI: NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase inhibitors 6-phosphogluconic dehydrogenase inhibitor ChEBI: ChEBI: EC 1.1.1.44 inhibitor ChEBI: phosphogluconate dehydrogenase (NADP+ -dependent, decarboxylating) inhibitors 6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) inhibitor ChEBI: 6-phosphogluconic dehydrogenase inhibitors ChEBI: 6-phosphogluconate dehydrogenase (decarboxylating) inhibitor ChEBI: 6-phospho-D-gluconate dehydrogenase inhibitor ChEBI: Wikipedia Wikipedia:Phosphogluconate_dehydrogenase_(decarboxylating) 6-phospho-D-gluconate dehydrogenase inhibitors ChEBI: 6-phosphogluconic carboxylase inhibitors ChEBI: 6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) inhibitors ChEBI: ChEBI: phosphogluconate dehydrogenase (NADP+ -dependent, decarboxylating) inhibitor ChEBI: phosphogluconic acid dehydrogenase inhibitor antidote to paracetamol poisoning A role borne by a molecule that acts to counteract or neutralize the deleterious effects of paracetamol (acetaminophen). CHEBI:74529 CiteXplore:16354242 CiteXplore:16573399 CiteXplore:16575097 CiteXplore:22348679 CiteXplore:22352734 CiteXplore:22353666 CiteXplore:22835053 CiteXplore:22998987 CiteXplore:7112203 Tylenol poisoning antidote Tylenol poisoning antidotes acetaminophen poisoning antidote acetaminophen poisoning antidotes antidote to Tylenol poisoning antidote to acetaminophen poisoning antidotes to Tylenol poisoning antidotes to acetaminophen poisoning antidotes to paracetamol poisoning chebi_ontology paracetamol poisoning antidote paracetamol poisoning antidotes PubMed citation CiteXplore:22998987 ChEBI: antidote to Tylenol poisoning ChEBI: antidote to acetaminophen poisoning ChEBI: Tylenol poisoning antidote PubMed citation CiteXplore:16354242 PubMed citation CiteXplore:22835053 ChEBI: acetaminophen poisoning antidotes ChEBI: acetaminophen poisoning antidote PubMed citation CiteXplore:16575097 PubMed citation CiteXplore:16573399 ChEBI: antidotes to paracetamol poisoning PubMed citation CiteXplore:22353666 ChEBI: paracetamol poisoning antidote ChEBI: paracetamol poisoning antidotes PubMed citation CiteXplore:22352734 ChEBI: antidotes to Tylenol poisoning PubMed citation CiteXplore:22348679 PubMed citation CiteXplore:7112203 ChEBI: Tylenol poisoning antidotes ChEBI: antidotes to acetaminophen poisoning antidote to curare poisoning A role borne by a molecule that acts to counteract or neutralize the deleterious effects of curare. CHEBI:74530 CiteXplore:13358565 CiteXplore:13386996 CiteXplore:14128111 CiteXplore:1579914 CiteXplore:3896015 CiteXplore:5333582 CiteXplore:5352084 CiteXplore:7720787 antidote to curare antidote to tubocurarine antidote to tubocurarine poisoning antidotes to curare antidotes to curare poisoning antidotes to tubocurarine antidotes to tubocurarine poisoning chebi_ontology curare antidote curare antidotes curare poisoning antidote curare poisoning antidotes tubocurarine antidote tubocurarine antidotes PubMed citation CiteXplore:5333582 ChEBI: tubocurarine antidote ChEBI: antidote to tubocurarine ChEBI: curare poisoning antidotes ChEBI: curare antidotes ChEBI: antidote to tubocurarine poisoning ChEBI: antidote to curare PubMed citation CiteXplore:3896015 PubMed citation CiteXplore:13358565 PubMed citation CiteXplore:7720787 ChEBI: antidotes to tubocurarine ChEBI: antidotes to tubocurarine poisoning PubMed citation CiteXplore:14128111 PubMed citation CiteXplore:1579914 PubMed citation CiteXplore:13386996 PubMed citation CiteXplore:5352084 ChEBI: curare antidote ChEBI: antidotes to curare ChEBI: antidotes to curare poisoning ChEBI: tubocurarine antidotes ChEBI: curare poisoning antidote gamma-glutamyltransferase inhibitor (5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase inhibitor (5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase inhibitors An enzyme inhibitor that interferes with the action of gamma-glutamyltransferase (EC 2.3.2.2). CHEBI:74570 EC 2.3.2.2 inhibitor EC 2.3.2.2 inhibitors GGT inhibitor GGT inhibitors L-gamma-glutamyl transpeptidase inhibitor L-gamma-glutamyl transpeptidase inhibitors L-gamma-glutamyltransferase inhibitor L-gamma-glutamyltransferase inhibitors L-glutamyltransferase inhibitor L-glutamyltransferase inhibitors Wikipedia:Gamma-glutamyl_transpeptidase alpha-glutamyl transpeptidase inhibitor alpha-glutamyl transpeptidase inhibitors chebi_ontology gamma-GPT inhibitor gamma-GPT inhibitors gamma-GT inhibitor gamma-GT inhibitors gamma-GTP inhibitor gamma-GTP inhibitors gamma-glutamyl peptidyltransferase inhibitor gamma-glutamyl peptidyltransferase inhibitors gamma-glutamyl transpeptidase inhibitor gamma-glutamyl transpeptidase inhibitors gamma-glutamyltransferase inhibitors gamma-glutamyltranspeptidase inhibitor gamma-glutamyltranspeptidase inhibitors glutamyl transpeptidase inhibitor glutamyl transpeptidase inhibitors ChEBI: EC 2.3.2.2 inhibitor ChEBI: gamma-glutamyl peptidyltransferase inhibitors ChEBI: gamma-GT inhibitors ChEBI: gamma-glutamyl transpeptidase inhibitors ChEBI: L-gamma-glutamyl transpeptidase inhibitor (5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase inhibitors ChEBI: ChEBI: GGT inhibitor ChEBI: gamma-glutamyltransferase inhibitors ChEBI: L-gamma-glutamyltransferase inhibitor ChEBI: gamma-GPT inhibitors ChEBI: gamma-GTP inhibitors ChEBI: glutamyl transpeptidase inhibitors (5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase inhibitor ChEBI: ChEBI: gamma-GPT inhibitor ChEBI: L-gamma-glutamyl transpeptidase inhibitors Wikipedia Wikipedia:Gamma-glutamyl_transpeptidase ChEBI: L-glutamyltransferase inhibitor ChEBI: gamma-glutamyltranspeptidase inhibitors ChEBI: alpha-glutamyl transpeptidase inhibitors ChEBI: glutamyl transpeptidase inhibitor ChEBI: gamma-glutamyl peptidyltransferase inhibitor ChEBI: gamma-GTP inhibitor ChEBI: alpha-glutamyl transpeptidase inhibitor ChEBI: EC 2.3.2.2 inhibitors ChEBI: GGT inhibitors ChEBI: gamma-glutamyl transpeptidase inhibitor ChEBI: gamma-GT inhibitor ChEBI: L-glutamyltransferase inhibitors ChEBI: gamma-glutamyltranspeptidase inhibitor ChEBI: L-gamma-glutamyltransferase inhibitors astringent A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions. CHEBI:74783 Wikipedia:Astringent adstringent adstringents astringents chebi_ontology ChEBI: astringents Wikipedia Wikipedia:Astringent ChEBI: adstringents ChEBI: adstringent neoglycolipid probe A compound used as a probe during microarray analysis of oligosaccharide-protein interactions. CHEBI:74886 chebi_ontology microarray analysis reagent A reagent used in the immobilization of compounds prior to their use in microarray analysis. CHEBI:74914 chebi_ontology microarray analysis reagents ChEBI: microarray analysis reagents gamma-secretase inhibitor An enzyme inhibitor that inhibits the activity of gamma-secretase. CHEBI:74925 Gamma-secretase inhibitor Gamma-secretase inhibitors Wikipedia:Gamma_secretase chebi_ontology gamma-secretase inhibitors Wikipedia Wikipedia:Gamma_secretase ChEBI: Gamma-secretase inhibitor ChEBI: gamma-secretase inhibitors ChEBI: Gamma-secretase inhibitors ribonuclease T1 inhibitor An enzyme inhibitor that interfers with the action of ribonuclease T1 (EC 3.1.27.3) CHEBI:74949 RNase T1 inhibitor RNase T1 inhibitors T1 inhibitor T1 inhibitors chebi_ontology ribonuclease T1 inhibitors ChEBI: RNase T1 inhibitor ChEBI: T1 inhibitors ChEBI: T1 inhibitor ChEBI: ribonuclease T1 inhibitors ChEBI: RNase T1 inhibitors B-Raf inhibitor A serine/threonine kinase inhibitor that specifically inhibits human mutant serine/threonine kinase (B-Raf) B-Raf inhibitors BRAF inhibitor BRAF inhibitors CHEBI:75047 chebi_ontology human mutant serine/threonine kinase inhibitor human mutant serine/threonine kinase inhibitors BRAF inhibitors ChEBI: ChEBI: human mutant serine/threonine kinase inhibitors ChEBI: human mutant serine/threonine kinase inhibitor B-Raf inhibitors ChEBI: BRAF inhibitor ChEBI: chromogenic compound CHEBI:75050 Colourless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into coloured compounds. They are used in biochemical assays and in diagnosis as indicators, particularly in the form of enzyme substrates. chebi_ontology chromogen chromogenic compounds chromogens ChEBI: chromogens ChEBI: chromogen ChEBI: chromogenic compounds squalene synthase inhibitor An enzyme inhibitor that interferes with the action of squalene synthase (EC 2.5.1.21). CHEBI:75174 Wikipedia:Squalene_synthase chebi_ontology farnesyl-diphosphate farnesyltransferase inhibitor farnesyl-diphosphate farnesyltransferase inhibitors squalene synthase inhibitors ChEBI: squalene synthase inhibitors ChEBI: farnesyl-diphosphate farnesyltransferase inhibitor Wikipedia Wikipedia:Squalene_synthase ChEBI: farnesyl-diphosphate farnesyltransferase inhibitors lysine 2,3-aminomutase inhibitor An enzyme inhibitor that interferes with the action of lysine 2,3-aminomutase. CHEBI:75190 chebi_ontology lysine 2,3-aminomutase inhibitors ChEBI: lysine 2,3-aminomutase inhibitors insulin-like growth factor receptor 1 antagonist An antagonist at the insulin-like growth factor receptor 1. CHEBI:75252 IGF-1R antagonist IGF-1R antagonists Wikipedia:Insulin-like_growth_factor_1_receptor chebi_ontology insulin-like growth factor receptor 1 antagonists ChEBI: IGF-1R antagonists Wikipedia Wikipedia:Insulin-like_growth_factor_1_receptor ChEBI: insulin-like growth factor receptor 1 antagonists ChEBI: IGF-1R antagonist ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. CHEBI:75282 CiteXplore:12604527 CiteXplore:19835945 chebi_ontology ergosterol biosynthesis inhibitors PubMed citation CiteXplore:19835945 ChEBI: ergosterol biosynthesis inhibitors PubMed citation CiteXplore:12604527 histamine releasing agent Any substance that can induce the release of histamine from mast cells. CHEBI:75298 chebi_ontology histamine releasing agents histamine releasing compound histamine releasing compounds histamine releasing substance histamine releasing substances ChEBI: histamine releasing compound ChEBI: histamine releasing substances ChEBI: histamine releasing compounds ChEBI: histamine releasing agents ChEBI: histamine releasing substance excipient A generally pharmacologically inactive substance that is formulated with the active ingredient of a medication. CHEBI:75324 CiteXplore:19709488 CiteXplore:21086329 CiteXplore:22707004 CiteXplore:22877709 CiteXplore:23450581 CiteXplore:23525964 CiteXplore:23657359 Wikipedia:Excipient bulking agent bulking agents chebi_ontology excipient filler fillers ChEBI: filler PubMed citation CiteXplore:19709488 PubMed citation CiteXplore:23450581 PubMed citation CiteXplore:23525964 ChEBI: excipient PubMed citation CiteXplore:21086329 ChEBI: bulking agent PubMed citation CiteXplore:22707004 ChEBI: bulking agents ChEBI: fillers Wikipedia Wikipedia:Excipient PubMed citation CiteXplore:23657359 PubMed citation CiteXplore:22877709 cathartic Any substance that accelerates defecation. Compare with laxatives, which are substances that ease defecation (usually by softening faeces). A substance can be both a laxative and a cathartic. CHEBI:75325 Wikipedia:Cathartic cathartics chebi_ontology Wikipedia Wikipedia:Cathartic ChEBI: cathartics curing agent A chemical additive used to toughen or harden a polymer material by cross-linking of polymer chains. CHEBI:75358 chebi_ontology curing agents vulcanization agent vulcanization agents vulcanizing agent vulcanizing agents ChEBI: vulcanization agents ChEBI: vulcanization agent ChEBI: vulcanizing agent ChEBI: curing agents ChEBI: vulcanizing agents catalase inhibitor An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of catalase (EC 1.11.1.6). CAT inhibitor CAT inhibitors CHEBI:75380 EC 1.11.1.6 inhibitor EC 1.11.1.6 inhibitors caperase inhibitor caperase inhibitors catalase inhibitors catalase-peroxidase inhibitor catalase-peroxidase inhibitors chebi_ontology equilase inhibitor equilase inhibitors hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitor hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitors optidase inhibitor optidase inhibitors ChEBI: catalase-peroxidase inhibitor ChEBI: EC 1.11.1.6 inhibitor ChEBI: equilase inhibitor ChEBI: hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitors ChEBI: equilase inhibitors ChEBI: optidase inhibitors ChEBI: caperase inhibitor ChEBI: optidase inhibitor ChEBI: hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitor ChEBI: caperase inhibitors ChEBI: catalase-peroxidase inhibitors ChEBI: catalase inhibitors ChEBI: EC 1.11.1.6 inhibitors CAT inhibitors ChEBI: CAT inhibitor ChEBI: peroxidases inhibitor An enzyme inhibitor that inhibits any of the peroxidases (EC 1.11.1.*). CHEBI:75381 EC 1.11.1 inhibitor EC 1.11.1 inhibitors EC 1.11.1.* inhibitor EC 1.11.1.* inhibitors Wikipedia:Peroxidases chebi_ontology inhibitor of peroxidases inhibitors of peroxidases peroxidases inhibitors ChEBI: peroxidases inhibitors ChEBI: EC 1.11.1.* inhibitor ChEBI: EC 1.11.1 inhibitors Wikipedia Wikipedia:Peroxidases ChEBI: EC 1.11.1 inhibitor ChEBI: inhibitor of peroxidases ChEBI: inhibitors of peroxidases ChEBI: EC 1.11.1.* inhibitors platelet-activating factor receptor agonist An agonist that binds to and activates platelet-activating factor receptors. CHEBI:75414 Wikipedia:Platelet-activating_factor_receptor chebi_ontology platelet-activating factor receptor agonists ChEBI: platelet-activating factor receptor agonists Wikipedia Wikipedia:Platelet-activating_factor_receptor aminoacyl tRNA synthetase inhibitor Any compound that inhibits the action of an aminoacyl tRNA synthetase. CHEBI:75416 aminoacyl tRNA synthetase inhibitors chebi_ontology tRNA synthetase inhibitor tRNA synthetase inhibitors ChEBI: tRNA synthetase inhibitor ChEBI: tRNA synthetase inhibitors ChEBI: aminoacyl tRNA synthetase inhibitors glycine decarboxylase inhibitor CHEBI:75429 chebi_ontology seryl-tRNA synthetase inhibitor An aminoacyl tRNA synthetase inhibitor that specifically inhibits the action of seryl-tRNA synthetase. CHEBI:75495 chebi_ontology seryl-tRNA synthetase inhibitors ChEBI: seryl-tRNA synthetase inhibitors alanine racemase inhibitor Any compound that inhibits the action of alanine racemase (EC 5.1.1.1). CHEBI:75595 EC 5.1.1.1 inhibitor EC 5.1.1.1 inhibitors L-alanine racemase inhibitor L-alanine racemase inhibitors Wikipedia:Alanine_racemase alanine racemase inhibitors chebi_ontology ChEBI: EC 5.1.1.1 inhibitors Wikipedia Wikipedia:Alanine_racemase ChEBI: L-alanine racemase inhibitors ChEBI: alanine racemase inhibitors ChEBI: L-alanine racemase inhibitor ChEBI: EC 5.1.1.1 inhibitor isomerase inhibitor An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*). CHEBI:75596 EC 5.* inhibitor EC 5.* inhibitors EC 5.*.*.* inhibitor EC 5.*.*.* inhibitors chebi_ontology isomerase inhibitors ChEBI: isomerase inhibitors ChEBI: EC 5.*.*.* inhibitors ChEBI: EC 5.* inhibitors ChEBI: EC 5.*.*.* inhibitor ChEBI: EC 5.* inhibitor D-alanine--D-alanine ligase inhibitor An acid--amino-acid ligase inhibitor that inhibits the action of a D-alanine--D-alanine ligase (EC 6.3.2.4). CHEBI:75598 D-alanine--D-alanine ligase inhibitors D-alanine:D-alanine ligase (ADP-forming) inhibitor D-alanine:D-alanine ligase (ADP-forming) inhibitors EC 6.3.2.4 inhibitor EC 6.3.2.4 inhibitors alanine:alanine ligase (ADP-forming) inhibitor alanine:alanine ligase (ADP-forming) inhibitors alanylalanine synthetase inhibitor alanylalanine synthetase inhibitors chebi_ontology ChEBI: alanylalanine synthetase inhibitor ChEBI: D-alanine--D-alanine ligase inhibitors ChEBI: alanine:alanine ligase (ADP-forming) inhibitors ChEBI: alanylalanine synthetase inhibitors ChEBI: D-alanine:D-alanine ligase (ADP-forming) inhibitor ChEBI: EC 6.3.2.4 inhibitors ChEBI: EC 6.3.2.4 inhibitor ChEBI: D-alanine:D-alanine ligase (ADP-forming) inhibitors ChEBI: alanine:alanine ligase (ADP-forming) inhibitor glutamate--cysteine ligase inhibitor An acid--amino-acid ligase inhibitor that inhibits the action of a glutamate--cysteine ligase (EC 6.3.2.2) CHEBI:75599 EC 6.3.2.2 inhibitor EC 6.3.2.2 inhibitors chebi_ontology gamma-glutamyl-L-cysteine synthetase inhibitor gamma-glutamyl-L-cysteine synthetase inhibitors gamma-glutamylcysteine synthetase inhibitor gamma-glutamylcysteine synthetase inhibitors gamma-glutamylcysteinyl synthetase inhibitor gamma-glutamylcysteinyl synthetase inhibitors glutamate--cysteine ligase inhibitors ChEBI: gamma-glutamylcysteine synthetase inhibitors ChEBI: gamma-glutamylcysteinyl synthetase inhibitors ChEBI: EC 6.3.2.2 inhibitors ChEBI: gamma-glutamyl-L-cysteine synthetase inhibitors ChEBI: EC 6.3.2.2 inhibitor ChEBI: glutamate--cysteine ligase inhibitors ChEBI: gamma-glutamylcysteinyl synthetase inhibitor ChEBI: gamma-glutamyl-L-cysteine synthetase inhibitor ChEBI: gamma-glutamylcysteine synthetase inhibitor C-N bond-forming ligase inhibitor Any inhibitor of a C-N bond-forming ligase (EC 6.3.*.*). C--N bond-forming ligase inhibitor C--N bond-forming ligase inhibitors C-N bond-forming ligase inhibitors CHEBI:75600 EC 6.3.* inhibitor EC 6.3.* inhibitors EC 6.3.*.* inhibitor EC 6.3.*.* inhibitors chebi_ontology ChEBI: EC 6.3.*.* inhibitors C--N bond-forming ligase inhibitor ChEBI: ChEBI: EC 6.3.* inhibitor C--N bond-forming ligase inhibitors ChEBI: ChEBI: EC 6.3.* inhibitors ChEBI: EC 6.3.*.* inhibitor C-N bond-forming ligase inhibitors ChEBI: ligase inhibitor Any enzyme inhibitor that inhibits a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. CHEBI:75603 EC 6.* inhibitor EC 6.* inhibitors EC 6.*.*.* inhibitor EC 6.*.*.* inhibitors chebi_ontology ligase inhibitors ChEBI: EC 6.*.*.* inhibitors ChEBI: EC 6.* inhibitor ChEBI: ligase inhibitors ChEBI: EC 6.*.*.* inhibitor ChEBI: EC 6.* inhibitors C-C bond-forming ligase inhibitor Any inhibitor of a C-C bond-forming ligase (EC 6.4.*.*). C--C bond-forming ligase inhibitor C--C bond-forming ligase inhibitors C-C bond-forming ligase inhibitorS CHEBI:75604 EC 6.4.* inhibitor EC 6.4.* inhibitors EC 6.4.*.* inhibitor EC 6.4.*.* inhibitors chebi_ontology C--C bond-forming ligase inhibitors ChEBI: C--C bond-forming ligase inhibitor ChEBI: C-C bond-forming ligase inhibitorS ChEBI: ChEBI: EC 6.4.*.* inhibitor ChEBI: EC 6.4.* inhibitor ChEBI: EC 6.4.* inhibitors ChEBI: EC 6.4.*.* inhibitors phosphoric ester bond-forming ligase inhibitor A ligase inhibitor which inhibits the action of a phosphoric ester bond-forming ligase (EC 6.5.*.*). CHEBI:75605 EC 6.5.* inhibitor EC 6.5.* inhibitors EC 6.5.*.* inhibitor EC 6.5.*.* inhibitors chebi_ontology phosphoric ester bond-forming ligase inhibitors ChEBI: phosphoric ester bond-forming ligase inhibitors ChEBI: EC 6.5.* inhibitor ChEBI: EC 6.5.*.* inhibitor ChEBI: EC 6.5.*.* inhibitors ChEBI: EC 6.5.* inhibitors bacterial metabolite Any prokaryotic metabolite produced during a metabolic reaction in a bacterium. CHEBI:75760 bacterial metabolites chebi_ontology ChEBI: bacterial metabolites Escherichia coli metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. CHEBI:75761 E.coli metabolite E.coli metabolites Escherichia coli metabolites chebi_ontology ChEBI: E.coli metabolite ChEBI: Escherichia coli metabolites ChEBI: E.coli metabolites eukaryotic metabolite Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms. CHEBI:75763 chebi_ontology eukaryotic metabolites ChEBI: eukaryotic metabolites fungal metabolite Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds. CHEBI:75765 chebi_ontology fungal metabolites ChEBI: fungal metabolites plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. CHEBI:75766 chebi_ontology plant metabolites ChEBI: plant metabolites animal metabolite Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to humans. CHEBI:75767 animal metabolites chebi_ontology ChEBI: animal metabolites mammalian metabolite Any animal metabolite produced during a metabolic reaction in mammals. CHEBI:75768 chebi_ontology mammalian metabolites ChEBI: mammalian metabolites B vitamin Any of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises vitamin B1, B2, B3, B5, B6, B7, B9, and B12. (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such.) B vitamins B-group vitamin B-group vitamins CHEBI:75769 CiteXplore:22743781 CiteXplore:23093174 CiteXplore:23238962 CiteXplore:23449527 CiteXplore:23462586 CiteXplore:23690582 Wikipedia:B_vitamin chebi_ontology vitamin B PubMed citation CiteXplore:23238962 PubMed citation CiteXplore:23690582 PubMed citation CiteXplore:23093174 PubMed citation CiteXplore:23462586 ChEBI: vitamin B B-group vitamins ChEBI: B-group vitamin ChEBI: Wikipedia Wikipedia:B_vitamin B vitamins ChEBI: PubMed citation CiteXplore:22743781 PubMed citation CiteXplore:23449527 human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). CHEBI:75770 H. sapiens metabolite H. sapiens metabolites Homo sapiens metabolite Homo sapiens metabolites chebi_ontology human metabolites ChEBI: human metabolites ChEBI: Homo sapiens metabolites ChEBI: H. sapiens metabolites ChEBI: Homo sapiens metabolite ChEBI: H. sapiens metabolite mouse metabolite Any mammalian metabolite produced during a metabolic reaction in mouse (Mus musculus). CHEBI:75771 Mus musculus metabolite Mus musculus metabolites chebi_ontology mouse metabolites ChEBI: mouse metabolites ChEBI: Mus musculus metabolite ChEBI: Mus musculus metabolites yeast metabolite Any fungal metabolite produced during a metabolic reaction in yeast (Saccharomyces cerevisiae). CHEBI:75772 S. cerevisiae metabolite S. cerevisiae metabolites Saccharomyces cerevisiae metabolite Saccharomyces cerevisiae metabolites baker's yeast metabolite baker's yeast metabolites chebi_ontology ChEBI: Saccharomyces cerevisiae metabolites ChEBI: baker's yeast metabolite ChEBI: S. cerevisiae metabolites ChEBI: S. cerevisiae metabolite ChEBI: Saccharomyces cerevisiae metabolite ChEBI: baker's yeast metabolites prokaryotic metabolite Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of the bacteria kingdom. CHEBI:75787 chebi_ontology prokaryotic metabolites ChEBI: prokaryotic metabolites Streptococcus pneumoniae metabolite Any bacterial metabolite produced during a metabolic reaction in Streptococcus pneumoniae. CHEBI:75789 S. pneumoniae metabolite S. pneumoniae metabolites Streptococcus pneumoniae metabolites chebi_ontology ChEBI: S. pneumoniae metabolites ChEBI: S. pneumoniae metabolite ChEBI: Streptococcus pneumoniae metabolites anti-anaemic agent CHEBI:75835 chebi_ontology Aspergillus metabolite Any fungal metabolite produced during a metabolic reaction in the mold, Aspergillus. Aspergillus metabolites CHEBI:75864 chebi_ontology Aspergillus metabolites ChEBI: Chaetomium metabolite Any fungal metabolite produced during a metabolic reaction in the mold, Chaetomium. CHEBI:75916 Chaetomium metabolites chebi_ontology ChEBI: Chaetomium metabolites Skp2 inhibitor An enzyme inhibitor that interferes with the action of S-phase kinase-associated protein 2 (Skp2). CHEBI:75968 S-phase kinase-associated protein 2 inhibitor S-phase kinase-associated protein 2 inhibitors Skp2 inhibitors Wikipedia:SKP2 chebi_ontology Wikipedia Wikipedia:SKP2 ChEBI: Skp2 inhibitors ChEBI: S-phase kinase-associated protein 2 inhibitors ChEBI: S-phase kinase-associated protein 2 inhibitor mitogen-activated protein kinase inhibitor Any protein kinase inhibitor that interferes with the action of mitogen-activated protein kinase. CHEBI:75997 MEK inhibitor MEK inhibitors Wikipedia:MEK_inhibitor chebi_ontology mitogen-activated protein kinase inhibitors ChEBI: MEK inhibitor Wikipedia Wikipedia:MEK_inhibitor ChEBI: MEK inhibitors ChEBI: mitogen-activated protein kinase inhibitors soluble guanylate cyclase activator An effector that binds to and activates soluble guanylate cyclase (EC 4.6.1.2). CHEBI:76022 Wikipedia:Soluble_guanylyl_cyclase chebi_ontology sGC activator sGC activators soluble guanylate cyclase activators soluble guanylyl cyclase activator soluble guanylyl cyclase activators ChEBI: sGC activator ChEBI: soluble guanylate cyclase activators Wikipedia Wikipedia:Soluble_guanylyl_cyclase ChEBI: soluble guanylyl cyclase activator ChEBI: soluble guanylyl cyclase activators ChEBI: sGC activators