part_of BFO:0000050 OBO_REL:part_of part_of has_part BFO:0000051 OBO_REL:has_part has_part occurs in BFO:0000066 occurs_in regulates RO:0002211 regulates positively_regulates RO:0002213 positively_regulates mitochondrial genome maintenance reproduction tryptophan biosynthetic process polysaccharide biosynthetic process proteasome complex mitochondrial RNA metabolic process regulatory region DNA binding transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding sequence-specific DNA binding RNA polymerase II transcription factor activity RNA polymerase II regulatory region DNA binding regulatory region nucleic acid binding nucleic acid binding transcription factor activity neurotransmitter uptake regulation of neurotransmitter levels angiogenesis blood vessel development angiotensin receptor activity peptide receptor activity G-protein coupled receptor binding lipid kinase activity cell activation regulation of protein phosphorylation positive regulation of protein phosphorylation vasculature development regulation of cytokine-mediated signaling pathway positive regulation of cytokine-mediated signaling pathway synaptic transmission, dopaminergic retinoic acid binding regulation of sodium ion transport immune system process regulation of immune system process positive regulation of immune system process regulation of leukocyte activation positive regulation of leukocyte activation peptide secretion regulation of peptide secretion positive regulation of peptide secretion developmental process involved in reproduction system process sphingosine-1-phosphate signaling pathway molecular_function nucleic acid binding DNA binding sequence-specific DNA binding transcription factor activity steroid hormone receptor activity retinoic acid receptor activity catalytic activity sterol 24-C-methyltransferase activity 4-aminobutyrate transaminase activity 4-hydroxyphenylpyruvate dioxygenase activity DNA topoisomerase activity DNA topoisomerase type II (ATP-hydrolyzing) activity IMP dehydrogenase activity NADH dehydrogenase activity NAD(P)H dehydrogenase (quinone) activity RNA-directed DNA polymerase activity acetolactate synthase activity acetylcholinesterase activity aconitate hydratase activity adenosine deaminase activity alditol:NADP+ 1-oxidoreductase activity aldo-keto reductase (NADP) activity alkaline phosphatase activity arachidonate 5-lipoxygenase activity arachidonate 12-lipoxygenase activity aromatic-L-amino-acid decarboxylase activity carbonate dehydratase activity chitin synthase activity cholinesterase activity cytochrome-c oxidase activity diacylglycerol O-acyltransferase activity dihydrofolate reductase activity dihydropteroate synthase activity endopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity exo-alpha-sialidase activity geranyltranstransferase activity glutamate-ammonia ligase activity glutaminase activity glycine hydroxymethyltransferase activity histone deacetylase activity phosphatidylinositol phospholipase C activity lipoprotein lipase activity monooxygenase activity monophenol monooxygenase activity squalene monooxygenase activity tyrosine 3-monooxygenase activity nitric-oxide synthase activity nuclease activity endonuclease activity endoribonuclease activity ribonuclease H activity ribonuclease activity hydrolase activity, hydrolyzing O-glycosyl compounds alpha-amylase activity alpha-glucosidase activity phospholipase activity phospholipase A2 activity phospholipase C activity prenyltransferase activity protein farnesyltransferase activity protein kinase activity protein serine/threonine kinase activity protein kinase C activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity purine-nucleoside phosphorylase activity riboflavin synthase activity serine C-palmitoyltransferase activity thymidylate synthase activity triglyceride lipase activity tryptophan synthase activity xanthine oxidase activity signal transducer activity receptor activity ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity glucocorticoid receptor activity thyroid hormone receptor activity transmembrane signaling receptor activity cytokine receptor activity erythropoietin receptor activity G-protein coupled receptor activity cannabinoid receptor activity icosanoid receptor activity prostanoid receptor activity prostaglandin receptor activity endothelin receptor activity glucagon receptor activity gonadotropin-releasing hormone receptor activity ionotropic glutamate receptor activity alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity N-methyl-D-aspartate selective glutamate receptor activity olfactory receptor activity opioid receptor activity vasopressin receptor activity fibroblast growth factor-activated receptor activity vascular endothelial growth factor-activated receptor activity receptor signaling protein activity receptor binding smoothened binding hormone activity gonadotropin hormone-releasing hormone activity pheromone activity transporter activity ion channel activity intracellular ligand-gated ion channel activity intracellular ligand-gated calcium channel activity ryanodine-sensitive calcium-release channel activity extracellular ligand-gated ion channel activity gap junction channel activity cation channel activity calcium channel activity potassium channel activity sodium channel activity neurotransmitter transporter activity calcium-transporting ATPase activity sodium:potassium-exchanging ATPase activity binding retinoid binding protein binding cellular_component intracellular cell cytoplasm mitochondrion mitochondrial envelope mitochondrial inner membrane mitochondrial respiratory chain mitochondrial respiratory chain complex III cytoskeleton microtubule cytoplasmic microtubule plasma membrane integral to plasma membrane carbohydrate metabolic process polysaccharide metabolic process aminoglycan metabolic process aminoglycan biosynthetic process chitin metabolic process chitin biosynthetic process amino sugar metabolic process cellular glucan metabolic process organic acid metabolic process generation of precursor metabolites and energy regulation of carbohydrate metabolic process nucleobase-containing compound metabolic process regulation of nucleotide metabolic process purine nucleoside catabolic process purine nucleotide metabolic process purine nucleotide catabolic process ATP catabolic process DNA metabolic process DNA replication DNA-dependent DNA replication mitochondrial DNA replication regulation of DNA replication RNA-dependent DNA replication DNA modification DNA alkylation DNA methylation chromatin organization transcription, DNA-templated regulation of transcription, DNA-dependent regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter transcription from mitochondrial promoter translation regulation of translation cellular protein modification process protein phosphorylation protein dephosphorylation protein deacetylation cellular amino acid metabolic process regulation of cellular amino acid metabolic process tryptophan metabolic process cellular biogenic amine metabolic process melanin metabolic process indolalkylamine metabolic process lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process phospholipid metabolic process glycerophospholipid metabolic process cellular aromatic compound metabolic process nucleoside phosphate metabolic process phosphorus metabolic process phosphate-containing compound metabolic process nitrogen compound metabolic process transport ion transport cation transport potassium ion transport sodium ion transport calcium ion transport phosphate ion transport hydrogen transport anion transport neurotransmitter transport serotonin transport response to stress organelle organization mitochondrion organization cell communication cell adhesion signal transduction cell surface receptor signaling pathway enzyme linked receptor protein signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway G-protein coupled receptor signaling pathway glutamate receptor signaling pathway cell-cell signaling synaptic transmission neuron-neuron synaptic transmission multicellular organismal development blood coagulation hemostasis sensory perception sensory perception of chemical stimulus sensory perception of smell glutamate receptor activity phosphoric diester hydrolase activity DNA-dependent ATPase activity alcohol dehydrogenase (NADP+) activity ceramide glucosyltransferase activity transcription factor binding NADH dehydrogenase (ubiquinone) activity biological_process metabolic process methyltransferase activity C-methyltransferase activity O-methyltransferase activity UDP-glycosyltransferase activity peptidase activity cysteine-type peptidase activity serine-type peptidase activity metallopeptidase activity exopeptidase activity regulation of G-protein coupled receptor protein signaling pathway ATP-sensitive potassium channel complex cell proliferation positive regulation of cell proliferation lipid binding protein prenyltransferase activity cation transmembrane transporter activity sialyltransferase activity O-acyltransferase activity acetylglucosaminyltransferase activity transaminase activity G-protein coupled peptide receptor activity fibroblast growth factor receptor signaling pathway potassium-transporting ATPase activity lipid biosynthetic process cellular amino acid biosynthetic process S-adenosylmethionine-dependent methyltransferase activity arginine decarboxylase activity cyclopropane-fatty-acyl-phospholipid synthase activity DNA-methyltransferase activity urease activity catabolic process biosynthetic process macromolecule biosynthetic process aromatic amino acid family metabolic process aromatic amino acid family biosynthetic process nucleoside metabolic process nucleotide metabolic process regulation of nucleoside metabolic process ribonucleoside metabolic process nucleoside monophosphate metabolic process nucleoside monophosphate catabolic process purine nucleoside monophosphate metabolic process purine nucleoside monophosphate catabolic process nucleoside triphosphate metabolic process nucleoside triphosphate catabolic process purine nucleoside triphosphate metabolic process purine nucleoside triphosphate catabolic process purine ribonucleotide metabolic process purine ribonucleotide catabolic process ribonucleoside monophosphate catabolic process ribonucleoside monophosphate metabolic process nucleoside catabolic process nucleotide catabolic process purine ribonucleoside monophosphate metabolic process purine ribonucleoside monophosphate catabolic process ribonucleoside triphosphate metabolic process ribonucleoside triphosphate catabolic process purine ribonucleoside triphosphate metabolic process purine ribonucleoside triphosphate catabolic process glucan biosynthetic process ribonucleotide metabolic process ribonucleotide catabolic process amine metabolic process amine biosynthetic process cytochrome b6f complex photosystem photosystem I photosystem II thylakoid detection of chemical stimulus response to external stimulus response to wounding anatomical structure morphogenesis response to endogenous stimulus response to hormone hormone-mediated signaling pathway photosynthetic electron transport chain regulation of biosynthetic process positive regulation of biosynthetic process positive regulation of metabolic process regulation of catabolic process positive regulation of catabolic process hormone transport regulation of signal transduction positive regulation of signal transduction cellular process response to organic substance regulation of photosynthesis regulation of proton transport response to organonitrogen compound gene expression regulation of gene expression regulation of receptor activity regulation of phospholipase activity positive regulation of phospholipase activity regulation of platelet activation regulation of macromolecule biosynthetic process positive regulation of macromolecule biosynthetic process positive regulation of phosphorus metabolic process regulation of cellular ketone metabolic process positive regulation of platelet activation positive regulation of macromolecule metabolic process posttranscriptional regulation of gene expression positive regulation of gene expression positive regulation of organelle organization regulation of cell communication positive regulation of cell communication regulation of cellular carbohydrate metabolic process positive regulation of cellular carbohydrate metabolic process regulation of alkaline phosphatase activity positive regulation of alkaline phosphatase activity positive regulation of sodium ion transport regulation of hormone levels regulation of mitochondrion organization positive regulation of mitochondrion organization positive regulation of phospholipase C activity regulation of isomerase activity positive regulation of isomerase activity regulation of phosphatase activity positive regulation of phosphatase activity positive regulation of endopeptidase activity positive regulation of peptidase activity regulation of metal ion transport regulation of glucan biosynthetic process regulation of phosphate transport response to organic cyclic compound heme-copper terminal oxidase activity ion transmembrane transporter activity monovalent inorganic cation transmembrane transporter activity hydrogen ion transmembrane transporter activity potassium ion transmembrane transporter activity sodium ion transmembrane transporter activity calcium ion transmembrane transporter activity channel activity ligand-gated ion channel activity calcium-release channel activity primary active transmembrane transporter activity P-P-bond-hydrolysis-driven transmembrane transporter activity microtubule cytoskeleton ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism monovalent inorganic cation transport inorganic anion transport peptide transport amine transport monoamine transport organic hydroxy compound transport dopamine transport glucosidase activity glutamate synthase activity photosynthesis proton transport membrane integral to membrane cellular component organization carbohydrate biosynthetic process organic acid biosynthetic process RNA metabolic process amylase activity linoleate 13S-lipoxygenase activity catechol O-methyltransferase activity ammonia ligase activity lipase activity kinase activity phosphorylation dephosphorylation cell-cell adhesion C-acyltransferase activity palmitoyltransferase activity N-acyltransferase activity acylglycerol O-acyltransferase activity C-palmitoyltransferase activity pyrophosphatase activity oxidoreductase activity protein-hormone receptor activity chromatin modification covalent chromatin modification histone modification histone deacetylation glutamate binding amino acid binding oxidoreductase activity, acting on CH-OH group of donors oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor oxidoreductase activity, acting on the CH-CH group of donors oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor oxidoreductase activity, acting on the CH-NH2 group of donors oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor oxidoreductase activity, acting on the CH-NH group of donors oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor oxidoreductase activity, acting on NAD(P)H oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor oxidoreductase activity, acting on a heme group of donors oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor oxidoreductase activity, acting on single donors with incorporation of molecular oxygen oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on CH or CH2 groups oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor transferase activity transferase activity, transferring one-carbon groups hydroxymethyl-, formyl- and related transferase activity transferase activity, transferring aldehyde or ketonic groups transferase activity, transferring acyl groups transferase activity, transferring acyl groups other than amino-acyl groups transferase activity, transferring glycosyl groups transferase activity, transferring hexosyl groups transferase activity, transferring pentosyl groups transferase activity, transferring alkyl or aryl (other than methyl) groups transferase activity, transferring nitrogenous groups transferase activity, transferring phosphorus-containing groups phosphotransferase activity, alcohol group as acceptor nucleotidyltransferase activity hydrolase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity, acting on glycosyl bonds dipeptidase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines hydrolase activity, acting on acid anhydrides hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances hydrolase activity, acting on acid carbon-phosphorus bonds lyase activity carbon-carbon lyase activity carboxy-lyase activity carbon-oxygen lyase activity hydro-lyase activity carbon-nitrogen lyase activity ammonia-lyase activity isomerase activity ligase activity ligase activity, forming carbon-nitrogen bonds acid-ammonia (or amide) ligase activity acid-amino acid ligase activity ATPase activity endoribonuclease activity, producing 5'-phosphomonoesters endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor alpha-sialidase activity peptide hormone binding nucleoside-triphosphatase activity fibroblast growth factor binding serine hydrolase activity peptidyl-tyrosine phosphorylation heterocycle biosynthetic process peptidyl-amino acid modification peptidyl-tyrosine modification phenol-containing compound metabolic process transmembrane receptor protein kinase activity deacetylase activity regulation of lipid metabolic process regulation of fatty acid metabolic process regulation of nucleobase-containing compound metabolic process regulation of phosphate metabolic process cytokine-mediated signaling pathway regulation of metabolic process transmission of nerve impulse deaminase activity aromatic compound biosynthetic process aromatic compound catabolic process protein metabolic process organophosphate metabolic process photosynthesis, light reaction ribose phosphate metabolic process secondary metabolic process carboxylic acid metabolic process cation-transporting ATPase activity growth factor binding isoprenoid binding organelle inner membrane cytokine binding regulation of cell-cell adhesion positive regulation of cell-cell adhesion reproductive process regulation of anatomical structure morphogenesis biological adhesion passive transmembrane transporter activity active transmembrane transporter activity transmitter-gated ion channel activity wide pore channel activity ligand-gated channel activity transmitter-gated channel activity gated channel activity substrate-specific channel activity ion gated channel activity GABA-gated chloride ion channel activity transmembrane transporter activity inorganic cation transmembrane transporter activity substrate-specific transmembrane transporter activity substrate-specific transporter activity regulation of transmembrane transporter activity electron transport chain signal transduction involved in regulation of gene expression regulation of signaling signaling positive regulation of signaling signal release metal ion transport peptide hormone secretion insulin secretion bacterial thylakoid plasma membrane-derived photosystem I plasma membrane-derived thylakoid photosystem II regulation of cell adhesion platelet activation regulation of blood coagulation positive regulation of blood coagulation cellulose metabolic process cellulose biosynthetic process lipid modification estrogen receptor activity heparanase activity intracellular steroid hormone receptor signaling pathway intracellular receptor signaling pathway receptor regulator activity receptor activator activity regulation of nucleotide catabolic process positive regulation of nucleotide catabolic process regulation of histone modification positive regulation of histone modification regulation of histone deacetylation positive regulation of histone deacetylation organelle membrane intrinsic to membrane intrinsic to plasma membrane regulation of cellular metabolic process positive regulation of cellular metabolic process regulation of cellular biosynthetic process positive regulation of cellular biosynthetic process regulation of cellular catabolic process positive regulation of cellular catabolic process regulation of protein modification process positive regulation of protein modification process carboxylic acid binding opioid receptor binding regulation of neurological system process positive regulation of neurological system process adrenergic receptor binding alpha-1B adrenergic receptor binding delta-type opioid receptor binding kappa-type opioid receptor binding corticosteroid receptor signaling pathway response to corticosteroid mitochondrial membrane organelle envelope envelope positive regulation of insulin secretion mitochondrial DNA metabolic process regulation of nuclease activity positive regulation of nuclease activity positive regulation of protein binding regulation of response to external stimulus positive regulation of response to external stimulus regulation of synaptic transmission, dopaminergic positive regulation of synaptic transmission, dopaminergic methylation regulation of cellular protein metabolic process positive regulation of cellular protein metabolic process regulation of intracellular transport positive regulation of intracellular transport regulation of transporter activity positive regulation of transporter activity regulation of ion transmembrane transporter activity positive regulation of ion transmembrane transporter activity regulation of phospholipase A2 activity positive regulation of phospholipase A2 activity multicellular organismal process developmental process positive regulation of phosphoprotein phosphatase activity mitochondrial translation regulation of monooxygenase activity positive regulation of monooxygenase activity regulation of monophenol monooxygenase activity positive regulation of monophenol monooxygenase activity RNA biosynthetic process positive regulation of ATPase activity monocarboxylic acid metabolic process cellular response to hormone stimulus regulation of localization regulation of polysaccharide metabolic process regulation of chitin metabolic process regulation of chitin biosynthetic process regulation of polysaccharide biosynthetic process secretion by cell mononuclear cell proliferation regulation of mononuclear cell proliferation positive regulation of mononuclear cell proliferation regulation of beta-glucan metabolic process regulation of beta-glucan biosynthetic process macromolecular complex regulation of organelle organization regulation of chromosome organization regulation of purine nucleotide catabolic process positive regulation of purine nucleotide catabolic process regulation of intracellular steroid hormone receptor signaling pathway positive regulation of intracellular steroid hormone receptor signaling pathway amide binding regulation of cellular amine metabolic process positive regulation of cellular amine metabolic process monocarboxylic acid binding protein deacetylase activity positive regulation of kinase activity cellular polysaccharide biosynthetic process response to glucagon phosphonopyruvate hydrolase activity response to lipid DNA polymerase activity RNA polymerase activity response to cytokine homotypic cell-cell adhesion regulation of homotypic cell-cell adhesion positive regulation of homotypic cell-cell adhesion ion transmembrane transport photosynthetic membrane regulation of transcription by chromatin organization cellular carbohydrate biosynthetic process cellular nitrogen compound metabolic process cellular macromolecule biosynthetic process nucleobase-containing compound biosynthetic process nucleobase-containing compound catabolic process ion channel complex regulation of transmembrane transport positive regulation of transmembrane transport regulation of ion transmembrane transport positive regulation of ion transmembrane transport phosphatidylinositol 3-kinase activity ionotropic glutamate receptor signaling pathway UDP-glucosyltransferase activity glutamate receptor binding G-protein coupled glutamate receptor binding nuclear hormone receptor binding regulation of dephosphorylation regulation of protein dephosphorylation positive regulation of dephosphorylation positive regulation of protein dephosphorylation peptidyl-tyrosine dephosphorylation intracellular signal transduction protein deacylation multicellular organismal signaling sodium ion transmembrane transport cellular response to vascular endothelial growth factor stimulus response to erythropoietin cellular response to erythropoietin small molecule binding protein modification process opioid receptor signaling pathway signaling receptor activity sphingosine-1-phosphate receptor activity vascular endothelial growth factor signaling pathway vascular endothelial growth factor binding erythropoietin-mediated signaling pathway angiotensin-activated signaling pathway cannabinoid signaling pathway growth regulation of growth regulation of gene expression, epigenetic regulation of fibroblast growth factor receptor signaling pathway wound healing 5,10-methylenetetrahydrofolate-dependent methyltransferase activity T cell proliferation positive regulation of T cell proliferation T cell activation regulation of cell proliferation regulation of T cell proliferation cellular ketone metabolic process response to chemical peptide binding purine nucleoside metabolic process regulation of fatty acid biosynthetic process regulation of phosphorylation positive regulation of phosphorylation cellular biogenic amine biosynthetic process indole-containing compound metabolic process indole-containing compound biosynthetic process melanin biosynthetic process pigment metabolic process ribonucleoside catabolic process regulation of photosynthesis, light reaction hormone binding phosphoric ester hydrolase activity ATPase activity, coupled ATPase activity, coupled to transmembrane movement of ions ATPase activity, coupled to transmembrane movement of substances amide transport glucocorticoid receptor signaling pathway retinoic acid receptor binding positive regulation of catalytic activity ion binding anion binding macromolecule metabolic process organic acid binding organelle membrane-bounded organelle non-membrane-bounded organelle intracellular organelle intracellular membrane-bounded organelle intracellular non-membrane-bounded organelle protein complex regulation of carbohydrate biosynthetic process regulation of potassium ion transport positive regulation of potassium ion transport regulation of ion transport positive regulation of ion transport positive regulation of DNA binding regulation of protein binding steroid hormone mediated signaling pathway glucocorticoid mediated signaling pathway macromolecule modification macromolecule methylation response to peptide hormone oxoacid metabolic process regulation of secondary metabolic process regulation of ATPase activity regulation of generation of precursor metabolites and energy ATPase activity, coupled to movement of substances regulation of kinase activity regulation of lipid kinase activity regulation of phosphatidylinositol 3-kinase activity positive regulation of phosphatidylinositol 3-kinase activity sequence-specific DNA binding regulation of phosphoprotein phosphatase activity regulation of DNA methylation glucan metabolic process regulation of system process regulation of anion transport positive regulation of molecular function cellular amine metabolic process transcription regulatory region DNA binding cellular metabolic process primary metabolic process cellular catabolic process cellular biosynthetic process cellular lipid metabolic process cellular macromolecule metabolic process cellular carbohydrate metabolic process cellular polysaccharide metabolic process cellular protein metabolic process cellular nitrogen compound catabolic process cellular nitrogen compound biosynthetic process small molecule metabolic process small molecule biosynthetic process sodium-dependent phosphate transport cellular response to fibroblast growth factor stimulus organelle part intracellular part membrane part mitochondrial part cytoskeletal part thylakoid part cytoplasmic part intracellular organelle part mitochondrial membrane part plasma membrane part cell part secondary metabolite biosynthetic process single-organism process single organism signaling single-multicellular organism process single-organism metabolic process single-organism biosynthetic process single-organism catabolic process single-organism carbohydrate metabolic process DNA methylation or demethylation single-organism cellular process single-organism transport single-organism developmental process bioactive lipid receptor activity respiratory chain complex III plasma membrane respiratory chain complex III leukocyte activation phenylalanine ammonia-lyase activity positive regulation of fatty acid biosynthetic process positive regulation of translation positive regulation of DNA replication positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of cellular amino acid metabolic process regulation of angiogenesis positive regulation of angiogenesis positive regulation of cell adhesion positive regulation of lipid metabolic process regulation of protein kinase activity positive regulation of protein kinase activity positive regulation of transcription, DNA-dependent positive regulation of carbohydrate metabolic process positive regulation of fatty acid metabolic process positive regulation of growth positive regulation of nucleobase-containing compound metabolic process positive regulation of phosphate metabolic process positive regulation of transcription from RNA polymerase II promoter positive regulation of nucleoside metabolic process positive regulation of nucleotide metabolic process ATP metabolic process purine ribonucleoside metabolic process purine ribonucleoside catabolic process pigment biosynthetic process phenol-containing compound biosynthetic process indolalkylamine biosynthetic process amino sugar biosynthetic process carboxylic acid biosynthetic process organophosphate catabolic process heterocycle metabolic process glycerolipid metabolic process phosphatidylinositol metabolic process glucosyltransferase activity lymphocyte activation lymphocyte proliferation heterocycle catabolic process lipid phosphorylation phosphatidylinositol phosphorylation metal ion transmembrane transporter activity hormone secretion regulation of hormone secretion positive regulation of hormone secretion positive regulation of lipid biosynthetic process regulation of lipid biosynthetic process secretion intracellular transport retinoid X receptor binding alcohol oxidase activity cyclohexadienyl dehydrogenase activity regulation of melanin biosynthetic process positive regulation of melanin biosynthetic process retinoic acid receptor signaling pathway regulation of retinoic acid receptor signaling pathway positive regulation of retinoic acid receptor signaling pathway blood vessel morphogenesis positive regulation of biological process positive regulation of cellular process response to steroid hormone regulation of response to stimulus positive regulation of response to stimulus developmental growth cellular process involved in reproduction regulation of developmental growth positive regulation of developmental growth anatomical structure formation involved in morphogenesis system development anatomical structure development NADH dehydrogenase (quinone) activity sphingosine N-acyltransferase activity arachidonate 15-lipoxygenase activity icosanoid binding regulation of lymphocyte proliferation positive regulation of lymphocyte proliferation regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation regulation of biological process regulation of catalytic activity regulation of developmental process regulation of cellular process regulation of insulin secretion regulation of synaptic transmission positive regulation of synaptic transmission coagulation regulation of coagulation positive regulation of coagulation regulation of T cell activation regulation of cell activation positive regulation of cell activation positive regulation of T cell activation neurological system process regulation of body fluid levels response to stimulus detection of stimulus involved in sensory perception detection of chemical stimulus involved in sensory perception detection of chemical stimulus involved in sensory perception of smell regulation of nitric-oxide synthase activity positive regulation of nitric-oxide synthase activity regulation of lipoprotein lipase activity positive regulation of lipoprotein lipase activity regulation of secretion positive regulation of secretion regulation of transport positive regulation of transport regulation of DNA metabolic process positive regulation of DNA metabolic process regulation of sequence-specific DNA binding transcription factor activity positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of developmental process regulation of binding positive regulation of binding regulation of DNA binding regulation of cellular component organization positive regulation of cellular component organization regulation of nitrogen compound metabolic process positive regulation of nitrogen compound metabolic process regulation of phosphorus metabolic process localization dioxygenase activity establishment of localization regulation of multicellular organismal process positive regulation of multicellular organismal process regulation of protein metabolic process positive regulation of protein metabolic process regulation of lymphocyte activation positive regulation of lymphocyte activation regulation of RNA metabolic process positive regulation of RNA metabolic process beta-glucan metabolic process beta-glucan biosynthetic process chromosome organization regulation of hydrolase activity regulation of transferase activity regulation of lyase activity regulation of ligase activity regulation of oxidoreductase activity positive regulation of hydrolase activity positive regulation of transferase activity positive regulation of lyase activity positive regulation of ligase activity positive regulation of oxidoreductase activity response to glucocorticoid hormone receptor binding gonadotropin-releasing hormone binding regulation of neurotransmitter uptake positive regulation of neurotransmitter uptake dopamine uptake involved in synaptic transmission regulation of dopamine uptake involved in synaptic transmission positive regulation of dopamine uptake involved in synaptic transmission regulation of neurotransmitter transport positive regulation of neurotransmitter transport detection of stimulus serotonin uptake regulation of serotonin uptake positive regulation of serotonin uptake cellular localization establishment of localization in cell localization within membrane cellular response to stimulus regulation of calcium ion transport positive regulation of calcium ion transport regulation of sensory perception catecholamine uptake involved in synaptic transmission catecholamine transport regulation of catecholamine uptake involved in synaptic transmission positive regulation of catecholamine uptake involved in synaptic transmission regulation of amine transport positive regulation of amine transport regulation of transmission of nerve impulse positive regulation of transmission of nerve impulse regulation of peptidase activity regulation of endopeptidase activity diamine oxidase activity carboxylic ester hydrolase activity transmembrane transport nucleobase-containing small molecule metabolic process oxidation-reduction process angiogenesis involved in wound healing molecular transducer activity regulation of lipase activity positive regulation of lipase activity regulation of macromolecule metabolic process regulation of ryanodine-sensitive calcium-release channel activity positive regulation of ryanodine-sensitive calcium-release channel activity regulation of cellular localization developmental growth involved in morphogenesis regulation of endoribonuclease activity regulation of ribonuclease activity regulation of response to cytokine stimulus positive regulation of response to cytokine stimulus regulation of wound healing regulation of protein tyrosine kinase activity positive regulation of protein tyrosine kinase activity positive regulation of triglyceride lipase activity DNA topoisomerase II activity biological regulation regulation of biological quality regulation of molecular function peptidase activity, acting on L-amino acid peptides regulation of mitochondrial translation positive regulation of mitochondrial translation thyroid hormone binding aromatase activity respiratory chain plasma membrane respiratory chain platelet aggregation calcium ion transmembrane transport leukocyte proliferation regulation of leukocyte proliferation positive regulation of leukocyte proliferation divalent metal ion transport response to growth factor cellular response to chemical stimulus cellular response to organic substance cellular response to cytokine stimulus cellular response to growth factor stimulus cellular response to peptide hormone stimulus cellular response to glucagon stimulus cellular response to steroid hormone stimulus cellular response to corticosteroid stimulus cellular response to glucocorticoid stimulus cellular response to lipid cellular response to organic cyclic compound cellular response to organonitrogen compound cellular response to endogenous stimulus organic substance transport organic substance metabolic process nitrogen compound transport response to fibroblast growth factor cellular potassium ion transport potassium ion transmembrane transport cellular component organization or biogenesis DNA biosynthetic process regulation of protein serine/threonine kinase activity positive regulation of protein serine/threonine kinase activity cell periphery monocarboxylic acid biosynthetic process cardiovascular system development circulatory system development regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter divalent inorganic cation transmembrane transporter activity divalent inorganic cation transport purine-containing compound metabolic process purine-containing compound catabolic process regulation of primary metabolic process positive regulation of glycine hydroxymethyltransferase activity regulation of response to stress endothelin receptor signaling pathway positive regulation of deacetylase activity regulation of peptide transport positive regulation of lipid kinase activity regulation of peptide hormone secretion positive regulation of peptide hormone secretion regulation of cellular response to growth factor stimulus regulation of mitochondrial DNA replication positive regulation of mitochondrial DNA replication positive regulation of wound healing nucleic acid metabolic process nucleic acid phosphodiester bond hydrolysis regulation of protein deacetylation positive regulation of protein deacetylation regulation of DNA-dependent DNA replication regulation of platelet aggregation regulation of tryptophan metabolic process positive regulation of tryptophan metabolic process catecholamine uptake dopamine uptake sphingolipid mediated signaling pathway organic cyclic compound binding response to gonadotropin-releasing hormone cellular response to gonadotropin-releasing hormone sialylation direct ligand regulated sequence-specific DNA binding transcription factor activity regulation of serine-type endopeptidase activity positive regulation of serine-type endopeptidase activity regulation of protein kinase C activity positive regulation of protein kinase C activity regulation of hemostasis positive regulation of hemostasis regulation of receptor binding positive regulation of receptor binding regulation of lipid binding positive regulation of lipid binding regulation of glucocorticoid mediated signaling pathway positive regulation of glucocorticoid mediated signaling pathway regulation of phospholipase C activity regulation of secondary metabolite biosynthetic process positive regulation of secondary metabolite biosynthetic process regulation of glutamate receptor signaling pathway positive regulation of glutamate receptor signaling pathway regulation of purine nucleotide metabolic process positive regulation of purine nucleotide metabolic process regulation of vascular endothelial growth factor signaling pathway positive regulation of vascular endothelial growth factor signaling pathway regulation of potassium ion transmembrane transporter activity positive regulation of potassium ion transmembrane transporter activity regulation of calcium ion transmembrane transporter activity positive regulation of calcium ion transmembrane transporter activity glucosamine-containing compound metabolic process glucosamine-containing compound biosynthetic process carbohydrate derivative metabolic process carbohydrate derivative catabolic process carbohydrate derivative biosynthetic process nucleoside phosphate catabolic process regulation of vasculature development organic cyclic compound metabolic process organic cyclic compound catabolic process organic cyclic compound biosynthetic process heterocyclic compound binding regulation of potassium ion transmembrane transport positive regulation of potassium ion transmembrane transport positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus organonitrogen compound metabolic process organonitrogen compound catabolic process organonitrogen compound biosynthetic process fatty acid derivative binding organic substance catabolic process organic substance biosynthetic process alpha-amino acid metabolic process alpha-amino acid biosynthetic process organic hydroxy compound metabolic process organic hydroxy compound biosynthetic process response to peptide cellular response to peptide glycosyl compound metabolic process glycosyl compound catabolic process response to nitrogen compound cellular response to nitrogen compound response to oxygen-containing compound cellular response to oxygen-containing compound regulation of histone deacetylase activity positive regulation of histone deacetylase activity positive regulation of platelet aggregation regulation of mitochondrial DNA metabolic process positive regulation of mitochondrial DNA metabolic process regulation of calcium-transporting ATPase activity positive regulation of calcium-transporting ATPase activity regulation of sphingolipid mediated signaling pathway positive regulation of sphingolipid mediated signaling pathway regulation of chromatin organization regulation of sodium ion transmembrane transport positive regulation of sodium ion transmembrane transport positive regulation of endoribonuclease activity catalytic complex transmembrane transporter complex regulation of intracellular signal transduction positive regulation of intracellular signal transduction regulation of cellular response to vascular endothelial growth factor stimulus oxidoreductase complex regulation of multicellular organismal development positive regulation of DNA-dependent DNA replication regulation of cellular macromolecule biosynthetic process regulation of sodium-dependent phosphate transport positive regulation of sodium-dependent phosphate transport regulation of reproductive process positive regulation of reproductive process positive regulation of receptor activity regulation of DNA biosynthetic process regulation of cellular amino acid biosynthetic process positive regulation of cellular amino acid biosynthetic process regulation of N-methyl-D-aspartate selective glutamate receptor activity regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity regulation of glucocorticoid receptor signaling pathway positive regulation of glucocorticoid receptor signaling pathway regulation of DNA topoisomerase (ATP-hydrolyzing) activity positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity regulation of opioid receptor signaling pathway positive regulation of opioid receptor signaling pathway positive regulation of DNA biosynthetic process regulation of sodium ion transmembrane transporter activity positive regulation of sodium ion transmembrane transporter activity regulation of transcription regulatory region DNA binding positive regulation of transcription regulatory region DNA binding positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity regulation of cellulose biosynthetic process positive regulation of cellulose biosynthetic process regulation of RNA biosynthetic process positive regulation of chromosome organization regulation of cation channel activity positive regulation of cation channel activity chymotrypsin activity toxin activity neurotoxin activity cathepsin K activity cathepsin B activity chymase activity microbial collagenase activity