format-version: 1.2
data-version: clyh/releases/2020-05-29/clyh.owl
remark: Clytia hemisphaerica Development and Anatomy Ontology
ontology: clyh/clyh
property_value: http://purl.org/dc/elements/1.1/description "Anatomy, development and life cycle stages - planula, polyp, medusa/jellyfish - of the cnidarian hydrozoan species, Clytia hemiphaerica." xsd:string
property_value: http://purl.org/dc/elements/1.1/title "Clytia hemisphaerica Development and Anatomy Ontology (CLYH)" xsd:string
property_value: http://purl.org/dc/terms/license https://creativecommons.org/licenses/by/3.0/

[Term]
id: CL:0000000
name: cell
def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." []

[Term]
id: CLYH:0000001
name: gametogenesis
is_a: UBERON:0000105 ! life cycle stage

[Term]
id: CLYH:0000002
name: gametogenesis period
def: "phase of sexual reproduction in which certain cells of a female or male individual (parent) are transformed into specialized reproductive cells (gametes) that will initiate development of a progeny individual (offspring) upon fertilization." []
is_a: UBERON:0000105 ! life cycle stage
relationship: BFO:0000050 CLYH:0000001 ! part of gametogenesis

[Term]
id: CLYH:0000003
name: oogenesis period
is_a: UBERON:0000105 ! life cycle stage
relationship: BFO:0000050 CLYH:0000002 ! part of gametogenesis period

[Term]
id: CLYH:0000004
name: previtellogenic stage
def: "Entered into meiosis, DNA replicated, no yolk accumulation." []
relationship: BFO:0000050 CLYH:0000003 ! part of oogenesis period

[Term]
id: CLYH:0000005
name: oocyte growth period
relationship: BFO:0000050 CLYH:0000003 ! part of oogenesis period
relationship: RO:0002087 CLYH:0000004 ! immediately preceded by previtellogenic stage

[Term]
id: CLYH:0000006
name: stage I oocyte growth stage
def: "Meiotic Prophase I arrest, GV in centre, diameter x" []
relationship: BFO:0000050 CLYH:0000005 ! part of oocyte growth period
relationship: RO:0002087 CLYH:0000004 ! immediately preceded by previtellogenic stage
property_value: IAO:0000301 "Amiel and Houliston Dev. Biol (2009)" xsd:string

[Term]
id: CLYH:0000007
name: stage II oocyte growth stage
def: "Meiotic Prophase I arrest, GV off centre, diameter x" []
relationship: BFO:0000050 CLYH:0000005 ! part of oocyte growth period
relationship: RO:0002087 CLYH:0000006 ! immediately preceded by stage I oocyte growth stage
property_value: IAO:0000301 "Amiel and Houliston Dev. Biol (2009)" xsd:string

[Term]
id: CLYH:0000008
name: stage III oocyte growth stage
def: "Meiotic Prophase I arrest, GV off centre, diameter x" []
relationship: BFO:0000050 CLYH:0000005 ! part of oocyte growth period
relationship: RO:0002087 CLYH:0000007 ! immediately preceded by stage II oocyte growth stage
property_value: IAO:0000301 "Amiel and Houliston Dev. Biol (2009)" xsd:string

[Term]
id: CLYH:0000009
name: oocyte meiotic maturation
def: "oocyte undergoing meiosis completion from prophase I to G0  of first meiotic cycle" []
relationship: BFO:0000050 CLYH:0000003 ! part of oogenesis period
relationship: RO:0002087 CLYH:0000008 ! immediately preceded by stage III oocyte growth stage
property_value: IAO:0000301 "Amiel and Houliston Dev. Biol (2009)" xsd:string

[Term]
id: CLYH:0000010
name: spermatogenesis period
is_a: UBERON:0000105 ! life cycle stage
relationship: BFO:0000050 CLYH:0000002 ! part of gametogenesis period

[Term]
id: CLYH:0000011
name: spermatogonium stage
relationship: BFO:0000050 CLYH:0000010 ! part of spermatogenesis period

[Term]
id: CLYH:0000012
name: spermatid stage
relationship: BFO:0000050 CLYH:0000010 ! part of spermatogenesis period
relationship: RO:0002087 CLYH:0000011 ! immediately preceded by spermatogonium stage

[Term]
id: CLYH:0000013
name: embryonic development
is_a: UBERON:0000105 ! life cycle stage
relationship: RO:0002087 CLYH:0000001 ! immediately preceded by gametogenesis

[Term]
id: CLYH:0000014
name: gamete period
is_a: UBERON:0000105 ! life cycle stage
relationship: BFO:0000050 CLYH:0000013 ! part of embryonic development
relationship: RO:0002087 CLYH:0000002 ! immediately preceded by gametogenesis period

[Term]
id: CLYH:0000015
name: unfertilized egg stage
def: "matture female germ cell. not yet fertilized. Meiotic divisions complete. Spawned egg with female pronucleus." []
relationship: BFO:0000050 CLYH:0000014 ! part of gamete period
relationship: RO:0002087 CLYH:0000009 ! immediately preceded by oocyte meiotic maturation
property_value: IAO:0000301 "Amiel and Houliston Dev. Biol (2009)" xsd:string

[Term]
id: CLYH:0000016
name: spermatozoid stage
def: "mature male germ cell. " []
relationship: BFO:0000050 CLYH:0000014 ! part of gamete period
relationship: RO:0002087 CLYH:0000012 ! immediately preceded by spermatid stage

[Term]
id: CLYH:0000017
name: cleavage period
relationship: BFO:0000050 CLYH:0000013 ! part of embryonic development
relationship: RO:0002087 CLYH:0000014 ! immediately preceded by gamete period

[Term]
id: CLYH:0000018
name: one cell stage
def: "Zygote fertilized egg, zygote nucleus forms at animal pole (about 0-50 min post fertilization at 18 degree celsius)." []
synonym: " fertilised egg" EXACT []
synonym: "zygote " EXACT []
relationship: BFO:0000050 CLYH:0000017 ! part of cleavage period
relationship: RO:0002087 CLYH:0000014 ! immediately preceded by gamete period
property_value: IAO:0000301 "Y. Kraus et al in preparation?" xsd:string

[Term]
id: CLYH:0000019
name: 2-cell stage
def: "Two cell-stage embryo. First cleaveages unipolar and start at the animal pole (about 50-80 min post fertilization at 18 degree celsius)." []
relationship: BFO:0000050 CLYH:0000017 ! part of cleavage period
relationship: RO:0002087 CLYH:0000018 ! immediately preceded by one cell stage
property_value: IAO:0000301 "Y. Kraus et al in preparation?" xsd:string

[Term]
id: CLYH:0000020
name: 4-cell stage
def: "Four cell-stage embryo. Second cleaveages unipolar and start at the animal pole (about 80-110 min post fertilization at 18 degree celsius). " []
relationship: BFO:0000050 CLYH:0000017 ! part of cleavage period
relationship: RO:0002087 CLYH:0000019 ! immediately preceded by 2-cell stage

[Term]
id: CLYH:0000021
name: 8-cell stage
def: "Eight cell-stage embryo (about 2h post fertilization at 18 degree celsius)." []
relationship: BFO:0000050 CLYH:0000017 ! part of cleavage period
relationship: RO:0002087 CLYH:0000020 ! immediately preceded by 4-cell stage

[Term]
id: CLYH:0000022
name: 16-cell stage
def: "Sixteen cell-stage embryo (about 2.5h post fertilization at 18 degree celsius)." []
relationship: BFO:0000050 CLYH:0000017 ! part of cleavage period
relationship: RO:0002087 CLYH:0000021 ! immediately preceded by 8-cell stage

[Term]
id: CLYH:0000023
name: 32-cell stage
def: "thirty two cell-stage embryo (about 3h post fertilization at 18 degree celsius)." []
relationship: BFO:0000050 CLYH:0000017 ! part of cleavage period
relationship: RO:0002087 CLYH:0000022 ! immediately preceded by 16-cell stage

[Term]
id: CLYH:0000024
name: 64-cell stage
def: "sixty four cell-stage embryo (about 3h post fertilization at 18 degree celsius)." []
relationship: BFO:0000050 CLYH:0000017 ! part of cleavage period
relationship: RO:0002087 CLYH:0000023 ! immediately preceded by 32-cell stage

[Term]
id: CLYH:0000025
name: blastula period
relationship: BFO:0000050 CLYH:0000013 ! part of embryonic development
relationship: RO:0002087 CLYH:0000017 ! immediately preceded by cleavage period

[Term]
id: CLYH:0000026
name: early blastula stage
def: "Cells rounded and loosely adhered, Nuclei central  (5-6h post fertilization at 18 degree celsius)." []
relationship: BFO:0000050 CLYH:0000025 ! part of blastula period
relationship: RO:0002087 CLYH:0000024 ! immediately preceded by 64-cell stage

[Term]
id: CLYH:0000027
name: mid blastula stage
def: "Cell contacts extended, cells polarised, nuclei apical (8h post fertilization at 18 degree celsius)." []
relationship: BFO:0000050 CLYH:0000025 ! part of blastula period
relationship: RO:0002087 CLYH:0000026 ! immediately preceded by early blastula stage

[Term]
id: CLYH:0000028
name: late blastula stage
def: "Cell polarized and columnar, nuclei apical (9- 10h post fertilization at 18 degree celsius)." []
relationship: BFO:0000050 CLYH:0000025 ! part of blastula period
relationship: RO:0002087 CLYH:0000027 ! immediately preceded by mid blastula stage

[Term]
id: CLYH:0000029
name: gastrula period
relationship: BFO:0000050 CLYH:0000013 ! part of embryonic development
relationship: RO:0002087 CLYH:0000025 ! immediately preceded by blastula period

[Term]
id: CLYH:0000030
name: very early gastrula stage
def: "Visible pointed oral pole but no cell ingression, ciliogenesis starting (12-13h post fertilization at 18 degree celsius). " []
relationship: BFO:0000050 CLYH:0000025 ! part of blastula period
relationship: RO:0002087 CLYH:0000030 ! immediately preceded by very early gastrula stage

[Term]
id: CLYH:0000031
name: early gastrula stage
def: "A few cells ingressed at pointed oral pole, swimming started  (14-16h post fertilization at 18 degree celsius)." []
relationship: BFO:0000050 CLYH:0000025 ! part of blastula period
relationship: RO:0002087 CLYH:0000032 ! immediately preceded by mid gastrula stage

[Term]
id: CLYH:0000032
name: mid gastrula stage
def: "Ingression to fill balastotocoel half completed (17- 18h post fertilization at 18 degree celsius)" []
relationship: BFO:0000050 CLYH:0000025 ! part of blastula period
relationship: RO:0002087 CLYH:0000031 ! immediately preceded by early gastrula stage

[Term]
id: CLYH:0000033
name: late gastrula stage
def: "Blastocoel full, no epithelisation of internal cells (20h post fertilization at18 degree celsius" []
relationship: BFO:0000050 CLYH:0000025 ! part of blastula period
relationship: RO:0002087 CLYH:0000032 ! immediately preceded by mid gastrula stage

[Term]
id: CLYH:0000034
name: planula period
synonym: "larval development" EXACT []
is_a: UBERON:0000105 ! life cycle stage
relationship: BFO:0000050 CLYH:0000013 ! part of embryonic development
relationship: RO:0002087 CLYH:0000029 ! immediately preceded by gastrula period

[Term]
id: CLYH:0000035
name: planula P1 stage
def: "Epithelisation beginning at aboral pole (as seen at 24h post fertilization at 18 degree celsius)" []
relationship: BFO:0000050 CLYH:0000034 ! part of planula period
relationship: RO:0002087 CLYH:0000033 ! immediately preceded by late gastrula stage

[Term]
id: CLYH:0000036
name: planula P2 stage
def: "Visible central cavity (as seen at 48h post fertilization at 18 degree celsius)" []
relationship: BFO:0000050 CLYH:0000034 ! part of planula period
relationship: RO:0002087 CLYH:0000035 ! immediately preceded by planula P1 stage

[Term]
id: CLYH:0000037
name: planula P3 stage
def: "Competent to metamorphose as (72h post fertilization at 18 degree celsius)" []
relationship: BFO:0000050 CLYH:0000034 ! part of planula period
relationship: RO:0002087 CLYH:0000036 ! immediately preceded by planula P2 stage

[Term]
id: CLYH:0000038
name: aged planula stage
def: "Aged planula (> 3 days post fertilization at 18 degree celsius) but not received metamporphosis signal." []
relationship: BFO:0000050 CLYH:0000034 ! part of planula period
relationship: RO:0002087 CLYH:0000037 ! immediately preceded by planula P3 stage

[Term]
id: CLYH:0000040
name: metamorphosis period
is_a: UBERON:0000105 ! life cycle stage
relationship: RO:0002087 CLYH:0000034 ! immediately preceded by planula period

[Term]
id: CLYH:0000041
name: settled planula stage
def: "torpedo shape planula that stopped swimming" []
relationship: BFO:0000050 CLYH:0000040 ! part of metamorphosis period
relationship: RO:0002087 CLYH:0000034 ! immediately preceded by planula period

[Term]
id: CLYH:0000042
name: blob stage
def: "irregularly shaped metamorphosing planula attached to substrate, not yet flattened" []
relationship: BFO:0000050 CLYH:0000040 ! part of metamorphosis period
relationship: RO:0002087 CLYH:0000041 ! immediately preceded by settled planula stage

[Term]
id: CLYH:0000043
name: disc stage
def: "metamorphosing planula attached to the substrate and in shape of a flattened disc" []
relationship: BFO:0000050 CLYH:0000040 ! part of metamorphosis period
relationship: RO:0002087 CLYH:0000042 ! immediately preceded by blob stage

[Term]
id: CLYH:0000044
name: sculpted disc stage
def: "metamorphosing planula attached to the substrate and in shape of a flattened disc with sculpted indentations" []
relationship: BFO:0000050 CLYH:0000040 ! part of metamorphosis period
relationship: RO:0002087 CLYH:0000043 ! immediately preceded by disc stage

[Term]
id: CLYH:0000045
name: primary polyp stalk extension stage
def: "uniform extension emerging from the sculpted disc" []
relationship: BFO:0000050 CLYH:0000040 ! part of metamorphosis period
relationship: RO:0002087 CLYH:0000044 ! immediately preceded by sculpted disc stage

[Term]
id: CLYH:0000046
name: primary polyp developing head stage
def: "swollen distal extremity developing into a functional primary polyp head" []
relationship: BFO:0000050 CLYH:0000040 ! part of metamorphosis period
relationship: RO:0002087 CLYH:0000045 ! immediately preceded by primary polyp stalk extension stage

[Term]
id: CLYH:0000047
name: functional primary polyp stage
def: "theca of the primary polyp open on the oral side and mouth open" []
relationship: BFO:0000050 CLYH:0000040 ! part of metamorphosis period
relationship: RO:0002087 CLYH:0000046 ! immediately preceded by primary polyp developing head stage

[Term]
id: CLYH:0000049
name: colony phase
def: "colony containing  mature or developing gonozoids , gastrozoids and stolons." []
is_a: UBERON:0000105 ! life cycle stage
relationship: RO:0002087 CLYH:0000040 ! immediately preceded by metamorphosis period

[Term]
id: CLYH:0000050
name: gastrozoid development
relationship: BFO:0000050 CLYH:0000049 ! part of colony phase

[Term]
id: CLYH:0000051
name: stalk extenstion stage
def: "uniform extension emerging from the stolon as first stage of gastrozoid development" []
relationship: BFO:0000050 CLYH:0000050 ! part of gastrozoid development

[Term]
id: CLYH:0000052
name: developing head stage
def: "swollen distal extremity developing into a complete gastrozoid head" []
relationship: BFO:0000050 CLYH:0000050 ! part of gastrozoid development
relationship: RO:0002087 CLYH:0000051 ! immediately preceded by stalk extenstion stage

[Term]
id: CLYH:0000053
name: functional gastrozoid stage
def: "complete and functional gastrozoid with open hydrotheca and mouth" []
relationship: BFO:0000050 CLYH:0000050 ! part of gastrozoid development
relationship: RO:0002087 CLYH:0000052 ! immediately preceded by developing head stage

[Term]
id: CLYH:0000054
name: gonozoid development
def: "Non feeding polyp specialized in budding medusae" []
relationship: BFO:0000050 CLYH:0000049 ! part of colony phase

[Term]
id: CLYH:0000055
name: growing gonozoid stage
def: "growing and developing gonozoid" []
relationship: BFO:0000050 CLYH:0000054 ! part of gonozoid development

[Term]
id: CLYH:0000056
name: budding gonozoid stage
def: "mature gonozoid budding medusae" []
relationship: BFO:0000050 CLYH:0000054 ! part of gonozoid development
relationship: RO:0002087 CLYH:0000055 ! immediately preceded by growing gonozoid stage

[Term]
id: CLYH:0000057
name: non-budding gonozoid stage
def: "mature gonozoid not containing any medusa bud only central tube and disc-shaped cap" []
relationship: BFO:0000050 CLYH:0000054 ! part of gonozoid development
relationship: RO:0002087 CLYH:0000055 ! immediately preceded by growing gonozoid stage

[Term]
id: CLYH:0000059
name: medusa phase
is_a: UBERON:0000105 ! life cycle stage
relationship: RO:0002087 CLYH:0000054 ! immediately preceded by gonozoid development

[Term]
id: CLYH:0000060
name: medusa budding
relationship: BFO:0000050 CLYH:0000059 ! part of medusa phase
relationship: RO:0002087 CLYH:0000054 ! immediately preceded by gonozoid development

[Term]
id: CLYH:0000061
name: early medusa bud stage
def: "medusa bud with visible ectoderm, endoderm and entocodon" []
relationship: BFO:0000050 CLYH:0000060 ! part of medusa budding
relationship: RO:0002087 CLYH:0000056 ! immediately preceded by budding gonozoid stage

[Term]
id: CLYH:0000062
name: mid medusa bud stage
def: "medusa bud with forming subumbrella cavity" []
relationship: BFO:0000050 CLYH:0000060 ! part of medusa budding
relationship: RO:0002087 CLYH:0000061 ! immediately preceded by early medusa bud stage

[Term]
id: CLYH:0000063
name: late medusa bud stage
def: "medusa bud with with folding umbrella" []
relationship: BFO:0000050 CLYH:0000060 ! part of medusa budding
relationship: RO:0002087 CLYH:0000062 ! immediately preceded by mid medusa bud stage

[Term]
id: CLYH:0000064
name: medusa growth
relationship: BFO:0000050 CLYH:0000059 ! part of medusa phase
relationship: RO:0002087 CLYH:0000060 ! immediately preceded by medusa budding

[Term]
id: CLYH:0000065
name: 4-bulb medusa stage
def: "period of medusa growth between release medusa from gonozoid  until appearance of secondary tentacles. Only  4 tentacle bulbs present " []
synonym: "baby medusa stage" EXACT []
relationship: BFO:0000050 CLYH:0000064 ! part of medusa growth
relationship: RO:0002087 CLYH:0000063 ! immediately preceded by late medusa bud stage

[Term]
id: CLYH:0000066
name: 8-bulb medusa stage
def: "period of medusa growth when only 8 tentacles are present " []
relationship: BFO:0000050 CLYH:0000064 ! part of medusa growth
relationship: RO:0002087 CLYH:0000065 ! immediately preceded by 4-bulb medusa stage

[Term]
id: CLYH:0000067
name: 12-bulb medusa stage
def: "period of medusa growth when only 12 tentacles are present " []
synonym: "young medusa stage" EXACT []
relationship: BFO:0000050 CLYH:0000064 ! part of medusa growth
relationship: RO:0002087 CLYH:0000066 ! immediately preceded by 8-bulb medusa stage

[Term]
id: CLYH:0000068
name: 16-bulb immature medusa stage
def: "period of medusa growth when only 16 tentacles are present. No mature gametes (eg 5mm diameter) " []
relationship: BFO:0000050 CLYH:0000064 ! part of medusa growth
relationship: RO:0002087 CLYH:0000067 ! immediately preceded by 12-bulb medusa stage

[Term]
id: CLYH:0000069
name: mature adult medusa stage
def: "period of medusa growth when only 16 tentacles are present. Gonads contain mature gametes. (eg 10mm diameter)" []
relationship: BFO:0000050 CLYH:0000064 ! part of medusa growth
relationship: RO:0002087 CLYH:0000068 ! immediately preceded by 16-bulb immature medusa stage

[Term]
id: CLYH:1000001
name: multicellular organism

[Term]
id: CLYH:1000002
name: organism subdivision
is_obsolete: true

[Term]
id: CLYH:1000003
name: mouth
is_a: UBERON:0000061 ! anatomical structure

[Term]
id: CLYH:1000004
name: tentacle system
is_a: UBERON:0000061 ! anatomical structure

[Term]
id: CLYH:1000005
name: tentacle
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000004 ! part of tentacle system

[Term]
id: CLYH:1000006
name: tissue layer
is_a: UBERON:0000061 ! anatomical structure

[Term]
id: CLYH:1000007
name: ectoderm
is_obsolete: true

[Term]
id: CLYH:1000008
name: gastrula outer layer
def: "Outer layer of the gastrula." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000035 ! part of gastrula
relationship: RO:0002202 CLYH:1000074 ! develops from aboral pole of blastula
relationship: RO:0002488 CLYH:0000030 ! existence starts during very early gastrula stage
relationship: RO:0002492 CLYH:0000033 ! existence ends during late gastrula stage

[Term]
id: CLYH:1000009
name: oral gastrula outer layer
def: "Oral part of the outer layer of the gastrula." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000008 ! part of gastrula outer layer
relationship: RO:0002202 CLYH:1000068 ! develops from oral pole of blastula
relationship: RO:0002488 CLYH:0000030 ! existence starts during very early gastrula stage
relationship: RO:0002492 CLYH:0000033 ! existence ends during late gastrula stage

[Term]
id: CLYH:1000010
name: aboral gastrula outer layer
def: "Aboral part of the outer layer of the gastrula." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000008 ! part of gastrula outer layer
relationship: RO:0002202 CLYH:1000074 ! develops from aboral pole of blastula
relationship: RO:0002488 CLYH:0000030 ! existence starts during very early gastrula stage
relationship: RO:0002492 CLYH:0000033 ! existence ends during late gastrula stage

[Term]
id: CLYH:1000011
name: lateral gastrula outer layer
def: "Mid part of the outer layer of the gastrula." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000008 ! part of gastrula outer layer
relationship: RO:0002202 CLYH:1000031 ! develops from blastula
relationship: RO:0002488 CLYH:0000030 ! existence starts during very early gastrula stage
relationship: RO:0002492 CLYH:0000033 ! existence ends during late gastrula stage

[Term]
id: CLYH:1000012
name: planula ectoderm
def: "Outer layer of the planula." []
synonym: "planula outer layer" EXACT []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000040 ! part of planula larva
relationship: RO:0002202 CLYH:1000035 ! develops from gastrula
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage

[Term]
id: CLYH:1000013
name: oral planula ectoderm
def: "Oral part of the outer layer of the planula." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000012 ! part of planula ectoderm
relationship: RO:0002202 CLYH:1000035 ! develops from gastrula
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage

[Term]
id: CLYH:1000014
name: aboral planula ectoderm
def: "Aboral part of the outer layer of the planula." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000012 ! part of planula ectoderm
relationship: RO:0002202 CLYH:1000035 ! develops from gastrula
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage

[Term]
id: CLYH:1000015
name: endoderm
is_obsolete: true

[Term]
id: CLYH:1000016
name: gastrula ingressing cells
def: "Cells ingressing from the outer layer of the gastrula into the blastocoel." []
is_a: CL:0000000 ! cell
relationship: BFO:0000050 CLYH:1000035 ! part of gastrula
relationship: RO:0002202 CLYH:1000068 ! develops from oral pole of blastula
relationship: RO:0002488 CLYH:0000030 ! existence starts during very early gastrula stage
relationship: RO:0002492 CLYH:0000033 ! existence ends during late gastrula stage

[Term]
id: CLYH:1000017
name: oral gastrula ingressing cells
def: "Cells ingressing from the outer layer into the blastocoel on the oral side of the gastrula." []
is_a: CL:0000000 ! cell
relationship: BFO:0000050 CLYH:1000035 ! part of gastrula
relationship: RO:0002202 CLYH:1000031 ! develops from blastula
relationship: RO:0002488 CLYH:0000032 ! existence starts during mid gastrula stage

[Term]
id: CLYH:1000018
name: aboral gastrula ingressing cells
def: "Cells ingressing from the outer layer into the blastocoel on the aboral side of the gastrula." []
is_a: CL:0000000 ! cell
relationship: BFO:0000050 CLYH:1000035 ! part of gastrula
relationship: RO:0002202 CLYH:1000031 ! develops from blastula
relationship: RO:0002488 CLYH:0000032 ! existence starts during mid gastrula stage

[Term]
id: CLYH:1000019
name: planula endoderm
def: "Inner layer of the planula." []
synonym: "planula inner layer" EXACT []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000040 ! part of planula larva
relationship: RO:0002202 CLYH:1000035 ! develops from gastrula
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage

[Term]
id: CLYH:1000020
name: aboral planula endoderm
def: "Inner layer of the planula on the aboral side of the planula." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000019 ! part of planula endoderm
relationship: RO:0002202 CLYH:1000035 ! develops from gastrula
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage

[Term]
id: CLYH:1000021
name: oral planula endoderm
def: "Inner layer of the planula on the oral side of the planula." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000019 ! part of planula endoderm
relationship: RO:0002202 CLYH:1000035 ! develops from gastrula
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage

[Term]
id: CLYH:1000022
name: fertilized egg
def: "Cell formed by fusion of a mature female reproductive cell and a mature male reproductive cell at fertilization." []
synonym: "zygote" EXACT []
is_a: CL:0000000 ! cell
relationship: RO:0002202 CLYH:1000087 ! develops from gamete
relationship: RO:0002488 CLYH:0000018 ! existence starts during one cell stage
relationship: RO:0002492 CLYH:0000018 ! existence ends during one cell stage

[Term]
id: CLYH:1000023
name: embryo
def: "Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues." []
is_a: CLYH:1000001 ! multicellular organism
relationship: RO:0002202 CLYH:1000022 ! develops from fertilized egg
relationship: RO:0002488 CLYH:0000018 ! existence starts during one cell stage
relationship: RO:0002492 CLYH:0000033 ! existence ends during late gastrula stage

[Term]
id: CLYH:1000024
name: cleaving embryo
def: "Organism at the cleavage stage." []
is_a: CLYH:1000023 ! embryo
relationship: RO:0002492 CLYH:0000024 ! existence ends during 64-cell stage

[Term]
id: CLYH:1000025
name: 2-cell embryo
def: "Organism at the cleavage stage after the first cell division." []
is_a: CLYH:1000024 ! cleaving embryo
relationship: RO:0002488 CLYH:0000019 ! existence starts during 2-cell stage
relationship: RO:0002492 CLYH:0000019 ! existence ends during 2-cell stage

[Term]
id: CLYH:1000026
name: 4-cell embryo
def: "Organism at the cleavage stage after two division cycles." []
is_a: CLYH:1000024 ! cleaving embryo
relationship: RO:0002202 CLYH:1000025 ! develops from 2-cell embryo
relationship: RO:0002488 CLYH:0000020 ! existence starts during 4-cell stage
relationship: RO:0002492 CLYH:0000020 ! existence ends during 4-cell stage

[Term]
id: CLYH:1000027
name: 8-cell embryo
def: "Organism at the cleavage stage after three division cycles." []
is_a: CLYH:1000024 ! cleaving embryo
relationship: RO:0002202 CLYH:1000026 ! develops from 4-cell embryo
relationship: RO:0002488 CLYH:0000021 ! existence starts during 8-cell stage
relationship: RO:0002492 CLYH:0000021 ! existence ends during 8-cell stage

[Term]
id: CLYH:1000028
name: 16-cell embryo
def: "Organism at the cleavage stage after four division cycles." []
is_a: CLYH:1000024 ! cleaving embryo
relationship: RO:0002202 CLYH:1000027 ! develops from 8-cell embryo
relationship: RO:0002488 CLYH:0000022 ! existence starts during 16-cell stage
relationship: RO:0002492 CLYH:0000022 ! existence ends during 16-cell stage

[Term]
id: CLYH:1000029
name: 32-cell embryo
def: "Organism at the cleavage stage after five division cycles." []
is_a: CLYH:1000024 ! cleaving embryo
relationship: RO:0002202 CLYH:1000028 ! develops from 16-cell embryo
relationship: RO:0002488 CLYH:0000023 ! existence starts during 32-cell stage
relationship: RO:0002492 CLYH:0000023 ! existence ends during 32-cell stage

[Term]
id: CLYH:1000030
name: 64-cell embryo
def: "Organism at the cleavage stage after six division cycles." []
is_a: CLYH:1000024 ! cleaving embryo
relationship: RO:0002202 CLYH:1000029 ! develops from 32-cell embryo
relationship: RO:0002488 CLYH:0000024 ! existence starts during 64-cell stage

[Term]
id: CLYH:1000031
name: blastula
def: "Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel." []
is_a: CLYH:1000023 ! embryo
relationship: RO:0002202 CLYH:1000030 ! develops from 64-cell embryo
relationship: RO:0002488 CLYH:0000026 ! existence starts during early blastula stage
relationship: RO:0002492 CLYH:0000028 ! existence ends during late blastula stage

[Term]
id: CLYH:1000032
name: early blastula
def: "Blastula stage embryo before epithelisation. " []
is_a: CLYH:1000031 ! blastula
relationship: RO:0002492 CLYH:0000026 ! existence ends during early blastula stage

[Term]
id: CLYH:1000033
name: mid blastula
def: "Blastula stage embryo with polarised epithelial cells." []
is_a: CLYH:1000031 ! blastula
relationship: RO:0002202 CLYH:1000032 ! develops from early blastula
relationship: RO:0002488 CLYH:0000027 ! existence starts during mid blastula stage
relationship: RO:0002492 CLYH:0000027 ! existence ends during mid blastula stage

[Term]
id: CLYH:1000034
name: late blasutla
def: "Blastula stage embryo with polarised and columnar epithelial cells." []
is_a: CLYH:1000031 ! blastula
relationship: RO:0002202 CLYH:1000033 ! develops from mid blastula
relationship: RO:0002488 CLYH:0000028 ! existence starts during late blastula stage

[Term]
id: CLYH:1000035
name: gastrula
def: "Organism at the gastrula stage." []
is_a: CLYH:1000023 ! embryo
relationship: RO:0002202 CLYH:1000034 ! develops from late blasutla
relationship: RO:0002488 CLYH:0000030 ! existence starts during very early gastrula stage

[Term]
id: CLYH:1000036
name: very early gastrula
def: "Visible pointed oral pole but no cell ingression, Ciliogenesis starting." []
is_a: CLYH:1000035 ! gastrula
relationship: RO:0002492 CLYH:0000030 ! existence ends during very early gastrula stage

[Term]
id: CLYH:1000037
name: early gastrula
def: "Gastrula with a few cells ingressed at pointed oral pole. Swimming." []
is_a: CLYH:1000035 ! gastrula
relationship: RO:0002202 CLYH:1000036 ! develops from very early gastrula
relationship: RO:0002488 CLYH:0000031 ! existence starts during early gastrula stage
relationship: RO:0002492 CLYH:0000031 ! existence ends during early gastrula stage

[Term]
id: CLYH:1000038
name: mid gastrula
def: "Gastrula in which blastotocoel is half filled with ingressing cells. " []
is_a: CLYH:1000035 ! gastrula
relationship: RO:0002202 CLYH:1000037 ! develops from early gastrula
relationship: RO:0002488 CLYH:0000032 ! existence starts during mid gastrula stage
relationship: RO:0002492 CLYH:0000032 ! existence ends during mid gastrula stage

[Term]
id: CLYH:1000039
name: late gastrula
def: "Gastrula in which Blastocoel is full but no epithelisation of internal cells." []
is_a: CLYH:1000035 ! gastrula
relationship: RO:0002202 CLYH:1000038 ! develops from mid gastrula
relationship: RO:0002488 CLYH:0000033 ! existence starts during late gastrula stage

[Term]
id: CLYH:1000040
name: planula larva
def: "A distinct juvenile form before metamorphosis with elongated shape and cilliated outer layer. Inner and outer tissue layers separated by basement membrane." []
is_a: CLYH:1000001 ! multicellular organism
relationship: RO:0002202 CLYH:1000039 ! develops from late gastrula
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage
relationship: RO:0002492 CLYH:0000041 ! existence ends during settled planula stage

[Term]
id: CLYH:1000041
name: planula P1
def: "Planula larva showing epithelisation of gastrodermal cells at aboral pole but not orally." []
is_a: CLYH:1000040 ! planula larva
relationship: RO:0002492 CLYH:0000035 ! existence ends during planula P1 stage

[Term]
id: CLYH:1000042
name: planula P2
def: "Planula larva with visible central cavity in gastrodermis, incompetent to metamorphose." []
is_a: CLYH:1000040 ! planula larva
relationship: RO:0002202 CLYH:1000041 ! develops from planula P1
relationship: RO:0002488 CLYH:0000036 ! existence starts during planula P2 stage
relationship: RO:0002492 CLYH:0000036 ! existence ends during planula P2 stage

[Term]
id: CLYH:1000043
name: planula P3 
def: "Planula larva with all cell types diffrerntiated and competent to metamorphose." []
is_a: CLYH:1000040 ! planula larva
relationship: RO:0002202 CLYH:1000042 ! develops from planula P2
relationship: RO:0002488 CLYH:0000037 ! existence starts during planula P3 stage
relationship: RO:0002492 CLYH:0000037 ! existence ends during planula P3 stage

[Term]
id: CLYH:1000044
name: aged planula
def: "Elongated planula competent to metamorphose, thinner than P3 planula." []
is_a: CLYH:1000040 ! planula larva
relationship: RO:0002202 CLYH:1000043 ! develops from planula P3
relationship: RO:0002488 CLYH:0000038 ! existence starts during aged planula stage
relationship: RO:0002492 CLYH:0000038 ! existence ends during aged planula stage

[Term]
id: CLYH:1000045
name: metamorphosing planula
def: "Planula larva that has stopped swimming and is transforming into a polyp." []
is_a: CLYH:1000001 ! multicellular organism
relationship: RO:0002202 CLYH:1000040 ! develops from planula larva
relationship: RO:0002488 CLYH:0000041 ! existence starts during settled planula stage
relationship: RO:0002492 CLYH:0000044 ! existence ends during sculpted disc stage

[Term]
id: CLYH:1000046
name: settled planula
def: "Planula larva that has stopped swimming and fixed to substrate." []
is_a: CLYH:1000045 ! metamorphosing planula
relationship: RO:0002492 CLYH:0000041 ! existence ends during settled planula stage

[Term]
id: CLYH:1000047
name: blob
def: "Metamorphosing larva that has a pear shape." []
is_a: CLYH:1000045 ! metamorphosing planula
relationship: RO:0002202 CLYH:1000046 ! develops from settled planula
relationship: RO:0002488 CLYH:0000042 ! existence starts during blob stage
relationship: RO:0002492 CLYH:0000042 ! existence ends during blob stage

[Term]
id: CLYH:1000048
name: disc
def: "Transitory form of planula undergoing metamorphosis a flattened circular form attached to the substrate." []
is_a: CLYH:1000045 ! metamorphosing planula
relationship: RO:0002202 CLYH:1000047 ! develops from blob
relationship: RO:0002488 CLYH:0000043 ! existence starts during disc stage
relationship: RO:0002492 CLYH:0000043 ! existence ends during disc stage

[Term]
id: CLYH:1000049
name: sculpted disc
def: "Transitory form of planula undergoing metamorphosis a flattened form attached to the substrate showing irregular indentations and with small stalk emerging." []
is_a: CLYH:1000045 ! metamorphosing planula
relationship: RO:0002202 CLYH:1000048 ! develops from disc
relationship: RO:0002488 CLYH:0000044 ! existence starts during sculpted disc stage

[Term]
id: CLYH:1000050
name: spindle-associated
def: "Region of the cell closely surrounding the mitotoc spindle." []
is_a: GO:0005575 ! cellular component
relationship: RO:0002488 CLYH:0000019 ! existence starts during 2-cell stage
relationship: RO:0002492 CLYH:0000024 ! existence ends during 64-cell stage

[Term]
id: CLYH:1000051
name: animal cortex 
def: "Region inheriting the peripheral region of the egg around the animal pole." []
is_a: GO:0005938 ! cell cortex
relationship: BFO:0000050 GO:0005575 ! part of cellular component
relationship: RO:0002488 CLYH:0000008 ! existence starts during stage III oocyte growth stage
relationship: RO:0002492 CLYH:0000017 ! existence ends during cleavage period

[Term]
id: CLYH:1000052
name: animal cortex of oocyte
is_a: CLYH:1000051 ! animal cortex
relationship: BFO:0000050 CLYH:1000084 ! part of oocyte

[Term]
id: CLYH:1000053
name: animal cortex of egg cell
is_a: CLYH:1000051 ! animal cortex
relationship: BFO:0000050 CLYH:1000088 ! part of egg cell
relationship: RO:0002202 CLYH:1000052 ! develops from animal cortex of oocyte

[Term]
id: CLYH:1000054
name: vegetal cortex
def: "Region inheriting the peripheral region of the egg around the vegetal pole." []
is_a: GO:0005938 ! cell cortex
relationship: BFO:0000050 GO:0005575 ! part of cellular component
relationship: RO:0002492 CLYH:0000017 ! existence ends during cleavage period

[Term]
id: CLYH:1000055
name: vegetal cortex of oocyte
def: "Region of a stage III oocyte cortex close to the oocyte nucleus." []
is_a: CLYH:1000054 ! vegetal cortex
relationship: BFO:0000050 CLYH:1000084 ! part of oocyte
relationship: RO:0002488 CLYH:0000008 ! existence starts during stage III oocyte growth stage
relationship: RO:0002492 CLYH:0000008 ! existence ends during stage III oocyte growth stage

[Term]
id: CLYH:1000056
name: vegetal cortex of egg
def: "Egg cortex region containing the site of polar body formation." []
is_a: CLYH:1000054 ! vegetal cortex
relationship: BFO:0000050 CLYH:1000088 ! part of egg cell
relationship: RO:0002202 CLYH:1000055 ! develops from vegetal cortex of oocyte

[Term]
id: CLYH:1000057
name: cytoplasm
is_a: GO:0005575 ! cellular component
relationship: BFO:0000050 GO:0005575 ! part of cellular component

[Term]
id: CLYH:1000058
name: animal cytoplasm
is_a: CLYH:1000057 ! cytoplasm

[Term]
id: CLYH:1000059
name: animal cytoplasm of oocyte
def: "Region of cytoplasm in a stage III oocyte in the same hemishere as the nucleus." []
is_a: CLYH:1000058 ! animal cytoplasm
relationship: BFO:0000050 CLYH:1000084 ! part of oocyte
relationship: RO:0002488 CLYH:0000008 ! existence starts during stage III oocyte growth stage
relationship: RO:0002492 CLYH:0000008 ! existence ends during stage III oocyte growth stage

[Term]
id: CLYH:1000060
name: animal cytoplasm of egg
def: "Cytoplasm in egg hemisphere containing site of polar body formation." []
is_a: CLYH:1000058 ! animal cytoplasm
relationship: BFO:0000050 CLYH:1000088 ! part of egg cell
relationship: RO:0002202 CLYH:1000059 ! develops from animal cytoplasm of oocyte

[Term]
id: CLYH:1000061
name: vegetal cytoplasm
is_a: CLYH:1000057 ! cytoplasm

[Term]
id: CLYH:1000062
name: vegetal cytoplasm of oocyte
is_a: CLYH:1000061 ! vegetal cytoplasm
relationship: BFO:0000050 CLYH:1000084 ! part of oocyte
relationship: RO:0002488 CLYH:0000008 ! existence starts during stage III oocyte growth stage
relationship: RO:0002492 CLYH:0000008 ! existence ends during stage III oocyte growth stage

[Term]
id: CLYH:1000063
name: vegetal cytoplasm of egg
is_a: CLYH:1000061 ! vegetal cytoplasm
relationship: BFO:0000050 CLYH:1000088 ! part of egg cell
relationship: RO:0002202 CLYH:1000062 ! develops from vegetal cytoplasm of oocyte

[Term]
id: CLYH:1000064
name: oral territory
is_a: UBERON:0000061 ! anatomical structure
relationship: RO:0002488 CLYH:0000019 ! existence starts during 2-cell stage
relationship: RO:0002492 CLYH:0000033 ! existence ends during late gastrula stage

[Term]
id: CLYH:1000065
name: oral pole of embryo
is_a: CLYH:1000064 ! oral territory
relationship: BFO:0000050 CLYH:1000023 ! part of embryo

[Term]
id: CLYH:1000066
name: oral pole of planula larva
is_a: CLYH:1000064 ! oral territory
relationship: BFO:0000050 CLYH:1000040 ! part of planula larva
relationship: RO:0002202 CLYH:1000065 ! develops from oral pole of embryo
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage
relationship: RO:0002492 CLYH:0000041 ! existence ends during settled planula stage

[Term]
id: CLYH:1000067
name: oral pole blastomeres
is_a: CLYH:1000064 ! oral territory
relationship: BFO:0000050 CLYH:1000024 ! part of cleaving embryo
relationship: RO:0002488 CLYH:0000021 ! existence starts during 8-cell stage
relationship: RO:0002492 CLYH:0000024 ! existence ends during 64-cell stage

[Term]
id: CLYH:1000068
name: oral pole of blastula
is_a: CLYH:1000064 ! oral territory
relationship: BFO:0000050 CLYH:1000031 ! part of blastula
relationship: RO:0002202 CLYH:1000067 ! develops from oral pole blastomeres

[Term]
id: CLYH:1000069
name: oral pole of gastrula
is_a: CLYH:1000064 ! oral territory
relationship: BFO:0000050 CLYH:1000035 ! part of gastrula

[Term]
id: CLYH:1000070
name: aboral territory 
is_a: UBERON:0000061 ! anatomical structure
relationship: RO:0002488 CLYH:0000019 ! existence starts during 2-cell stage
relationship: RO:0002492 CLYH:0000033 ! existence ends during late gastrula stage

[Term]
id: CLYH:1000071
name: aboral pole of embryo
is_a: CLYH:1000070 ! aboral territory
relationship: BFO:0000050 CLYH:1000023 ! part of embryo

[Term]
id: CLYH:1000072
name: aboral pole of planula larva
is_a: CLYH:1000070 ! aboral territory
relationship: BFO:0000050 CLYH:1000040 ! part of planula larva
relationship: RO:0002202 CLYH:1000071 ! develops from aboral pole of embryo
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage
relationship: RO:0002492 CLYH:0000041 ! existence ends during settled planula stage

[Term]
id: CLYH:1000073
name: aboral pole blastomeres
is_a: CLYH:1000070 ! aboral territory
relationship: BFO:0000050 CLYH:1000024 ! part of cleaving embryo
relationship: RO:0002488 CLYH:0000021 ! existence starts during 8-cell stage
relationship: RO:0002492 CLYH:0000024 ! existence ends during 64-cell stage

[Term]
id: CLYH:1000074
name: aboral pole of blastula
is_a: CLYH:1000070 ! aboral territory
relationship: BFO:0000050 CLYH:1000031 ! part of blastula
relationship: RO:0002202 CLYH:1000073 ! develops from aboral pole blastomeres

[Term]
id: CLYH:1000075
name: aboral pole of gastrula
is_a: CLYH:1000070 ! aboral territory
relationship: BFO:0000050 CLYH:1000035 ! part of gastrula

[Term]
id: CLYH:1000076
name: blastomere
def: "Single cell of a cleavage cel embryo." []
is_a: CL:0000000 ! cell
relationship: BFO:0000050 CLYH:1000024 ! part of cleaving embryo
relationship: RO:0002488 CLYH:0000019 ! existence starts during 2-cell stage
relationship: RO:0002492 CLYH:0000024 ! existence ends during 64-cell stage

[Term]
id: CLYH:1000077
name: germ cell
is_a: CL:0000000 ! cell
relationship: BFO:0000050 CLYH:1000192 ! part of gonad
relationship: RO:0002202 CLYH:1000160 ! develops from medusa
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000078
name: male germ cell
is_a: CLYH:1000077 ! germ cell

[Term]
id: CLYH:1000079
name: spermatogonium
def: "An undeveloped male germ cell. Spermatogonia develop into primary spermatocytes." []
is_a: CLYH:1000078 ! male germ cell
relationship: RO:0002202 CLYH:1000095 ! develops from interstitial cell

[Term]
id: CLYH:1000080
name: spermatid
def: "A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa." []
is_a: CLYH:1000078 ! male germ cell
relationship: RO:0002202 CLYH:1000079 ! develops from spermatogonium
relationship: RO:0002488 CLYH:0000066 ! existence starts during 8-bulb medusa stage

[Term]
id: CLYH:1000081
name: spermatozoid
def: "A mature male germ cell that develops from a spermatid." []
synonym: "sperm" EXACT []
is_a: CLYH:1000078 ! male germ cell
relationship: RO:0002202 CLYH:1000080 ! develops from spermatid
relationship: RO:0002488 CLYH:0000067 ! existence starts during 12-bulb medusa stage

[Term]
id: CLYH:1000082
name: female germ cell
is_a: CLYH:1000077 ! germ cell

[Term]
id: CLYH:1000083
name: oogonium
def: "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." []
is_a: CLYH:1000082 ! female germ cell

[Term]
id: CLYH:1000084
name: oocyte
def: "A female germ cell that has entered meiosis." []
is_a: CLYH:1000082 ! female germ cell
relationship: RO:0002202 CLYH:1000083 ! develops from oogonium

[Term]
id: CLYH:1000085
name: growing oocyte
def: "Oocyte incorporating yolk." []
is_a: CLYH:1000084 ! oocyte
relationship: RO:0002488 CLYH:0000066 ! existence starts during 8-bulb medusa stage

[Term]
id: CLYH:1000086
name: fully grown oocyte
def: "Oocyte greater than 150 micrometers in diameter competent to undergo meiotic maturation." []
is_a: CLYH:1000084 ! oocyte
relationship: RO:0002202 CLYH:1000085 ! develops from growing oocyte
relationship: RO:0002488 CLYH:0000006 ! existence starts during stage I oocyte growth stage
relationship: RO:0002492 CLYH:0000008 ! existence ends during stage III oocyte growth stage

[Term]
id: CLYH:1000087
name: gamete
def: "A mature sexual reproductive cell having a single set of unpaired chromosomes." []
is_a: CL:0000000 ! cell

[Term]
id: CLYH:1000088
name: egg cell
def: "A female gamete where meiosis is complete and is able to participate in fertilization." []
synonym: "female gamete" EXACT []
is_a: CLYH:1000087 ! gamete
relationship: RO:0002202 CLYH:1000086 ! develops from fully grown oocyte

[Term]
id: CLYH:1000089
name: blastocoel roof cell
is_a: CL:0000000 ! cell
relationship: BFO:0000050 CLYH:1000035 ! part of gastrula
relationship: RO:0002202 CLYH:1000031 ! develops from blastula
relationship: RO:0002488 CLYH:0000030 ! existence starts during very early gastrula stage

[Term]
id: CLYH:1000090
name: gland cell
def: "Specialized cell participating in mucus secretion." []
is_a: CL:0000000 ! cell

[Term]
id: CLYH:1000091
name: planula aboral gland cell
def: "Gland cell located on the aboral side of the planula larva, in the outer layer." []
is_a: CLYH:1000090 ! gland cell
relationship: BFO:0000050 CLYH:1000040 ! part of planula larva
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage

[Term]
id: CLYH:1000092
name: planula gland cell
def: "Gland cell located in the inner layer of the planula larva." []
is_a: CLYH:1000090 ! gland cell
relationship: BFO:0000050 CLYH:1000040 ! part of planula larva
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage

[Term]
id: CLYH:1000093
name: manubrium gland cell
def: "Gland cell of the manubrium." []
is_a: CLYH:1000090 ! gland cell
relationship: BFO:0000050 CLYH:1000187 ! part of manubrium
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000094
name: gastrozoid gland cell
def: "Gland cell of the gastrozoid." []
is_a: CLYH:1000090 ! gland cell
relationship: BFO:0000050 CLYH:1000150 ! part of gastrozoid

[Term]
id: CLYH:1000095
name: interstitial cell
def: "Multipotent stem cell." []
is_a: CL:0000000 ! cell

[Term]
id: CLYH:1000096
name: stolon interstitial cell
def: "Interstitial cell in the stolon." []
is_a: CLYH:1000095 ! interstitial cell
relationship: BFO:0000050 CLYH:1000128 ! part of stolon
relationship: RO:0002202 CLYH:1000040 ! develops from planula larva
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000097
name: embryo interstitial cell
def: "Interstitial cell in the embryo." []
is_a: CLYH:1000095 ! interstitial cell
relationship: BFO:0000050 CLYH:1000023 ! part of embryo

[Term]
id: CLYH:1000098
name: planula interstitial cell
def: "Interstitial cell in the planula." []
is_a: CLYH:1000095 ! interstitial cell
relationship: BFO:0000050 CLYH:1000040 ! part of planula larva

[Term]
id: CLYH:1000099
name: gastrozoid interstitial cell
def: "Interstitial cell in the feeding polyp." []
is_a: CLYH:1000095 ! interstitial cell
relationship: BFO:0000050 CLYH:1000150 ! part of gastrozoid

[Term]
id: CLYH:1000100
name: gonozoid interstitial cell
def: "Interstitial cell within the gonozoid." []
is_a: CLYH:1000095 ! interstitial cell
relationship: BFO:0000050 CLYH:1000134 ! part of gonozoid
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000101
name: manubrium interstital cell
def: "Interstital cell of the manubrium." []
is_a: CLYH:1000095 ! interstitial cell
relationship: BFO:0000050 CLYH:1000187 ! part of manubrium
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000102
name: nematoblast
def: "Differenciating nematocyte." []
is_a: CL:0000000 ! cell

[Term]
id: CLYH:1000103
name: stolon nematoblast
def: "Nematoblast in the stolon." []
is_a: CLYH:1000102 ! nematoblast
relationship: BFO:0000050 CLYH:1000128 ! part of stolon
relationship: RO:0002202 CLYH:1000040 ! develops from planula larva
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000104
name: planula nematoblast
def: "Nematoblast in the planula." []
is_a: CLYH:1000102 ! nematoblast
relationship: BFO:0000050 CLYH:1000040 ! part of planula larva

[Term]
id: CLYH:1000105
name: tentacle bulb nemtoblast
def: "Nematoblast of the tentacle bulb." []
is_a: CLYH:1000102 ! nematoblast
relationship: BFO:0000050 CLYH:1000171 ! part of nematogenic ectoderm of the bulb
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000106
name: manubrium nematoblast
def: "Nematoblast of the manubrium." []
is_a: CLYH:1000102 ! nematoblast
relationship: BFO:0000050 CLYH:1000187 ! part of manubrium
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000107
name: nematocyte
def: "Specialized cell containing one giant explosive secretory organelle called nematocyst used for prey capture and defense from predators." []
is_a: CL:0000000 ! cell

[Term]
id: CLYH:1000108
name: planula nematocyte
def: "Nematocyte of the planula." []
is_a: CLYH:1000107 ! nematocyte
relationship: BFO:0000050 CLYH:1000040 ! part of planula larva

[Term]
id: CLYH:1000109
name: medusa tentacle nematocyte
def: "Nematocyte of the medusa tentacle." []
is_a: CLYH:1000107 ! nematocyte
relationship: BFO:0000050 CLYH:1000174 ! part of medusa tentacle
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000110
name: manubrium nematocyte
def: "Nematocyte located on the manubrium." []
is_a: CLYH:1000107 ! nematocyte
relationship: BFO:0000050 CLYH:1000187 ! part of manubrium
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000111
name: gastrozoid tentacle nematocyte
def: "Nematocyte located on the tentacle." []
is_a: CLYH:1000107 ! nematocyte
relationship: BFO:0000050 CLYH:1000151 ! part of gastrozoid tentacle

[Term]
id: CLYH:1000112
name: neural cell
def: "A cell that is part of the nervous system." []
is_a: CL:0000000 ! cell

[Term]
id: CLYH:1000113
name: planula neural cell
def: "Neural cell in the planula." []
is_a: CLYH:1000112 ! neural cell
relationship: BFO:0000050 CLYH:1000040 ! part of planula larva

[Term]
id: CLYH:1000114
name: planula lateral neural cells
def: "Neural cell in the mid part of the planula." []
is_a: CLYH:1000113 ! planula neural cell
relationship: RO:0002202 CLYH:1000035 ! develops from gastrula
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage

[Term]
id: CLYH:1000115
name: plaunula aboral ectoderm neural cells
def: "Neural cell in the aboral part of the planula." []
is_a: CLYH:1000113 ! planula neural cell
relationship: RO:0002202 CLYH:1000035 ! develops from gastrula
relationship: RO:0002488 CLYH:0000035 ! existence starts during planula P1 stage

[Term]
id: CLYH:1000116
name: nerve cell of the radial canal
def: "Nerve cells of the radial canal." []
is_a: CLYH:1000112 ! neural cell
relationship: BFO:0000050 CLYH:1000182 ! part of radial canal
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000117
name: nerve cell of the circular canal
def: "Nerve cells of the circular canal." []
is_a: CLYH:1000112 ! neural cell
relationship: BFO:0000050 CLYH:1000183 ! part of circular canal
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000118
name: nerve cells of the gonad ectoderm
def: "Nerve cells located in the gonad outer layer." []
is_a: CLYH:1000112 ! neural cell
relationship: BFO:0000050 CLYH:1000192 ! part of gonad
relationship: RO:0002202 CLYH:1000160 ! develops from medusa
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000119
name: nerve cell of the tentacle bulb
def: "Nerve cell of the medusa tentacle bulb." []
is_a: CLYH:1000112 ! neural cell
relationship: BFO:0000050 CLYH:1000170 ! part of medusa tentacle bulb
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000120
name: subumbrella nervous cell
def: "Nervous cells of the subumbrella." []
is_a: CLYH:1000112 ! neural cell
relationship: BFO:0000050 CLYH:1000163 ! part of subumbrella
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000121
name: smooth muscle cell
def: "Epithelial cell containing smooth myofibers." []
is_a: CL:0000000 ! cell

[Term]
id: CLYH:1000122
name: smooth muscle of the velum
def: "Smooth muscle of the velum." []
is_a: CLYH:1000121 ! smooth muscle cell
relationship: BFO:0000050 CLYH:1000179 ! part of velum
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000123
name: subumbrella smooth muscle
def: "Smooth muscle of the subumbrella." []
is_a: CLYH:1000121 ! smooth muscle cell
relationship: BFO:0000050 CLYH:1000163 ! part of subumbrella
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000124
name: striated muscle cell
def: "Epithelial cell containing striated myofibers." []
is_a: CL:0000000 ! cell

[Term]
id: CLYH:1000125
name: striated muscle of the velum
def: "Striated muscle of the velum." []
is_a: CLYH:1000124 ! striated muscle cell
relationship: BFO:0000050 CLYH:1000179 ! part of velum
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000126
name: subumbrella striated muscle
def: "Striated muscle of the subumbrella." []
is_a: CLYH:1000124 ! striated muscle cell
relationship: BFO:0000050 CLYH:1000163 ! part of subumbrella
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000127
name: polyp colony
def: "Connected system of gastrozoid and gonozoid polyps, propagating vegetatively." []
is_a: CLYH:1000001 ! multicellular organism
relationship: RO:0002202 CLYH:1000040 ! develops from planula larva
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000128
name: stolon
def: "Tubular structure adhering to the substrate, connecting the bases of the polyps." []
relationship: BFO:0000050 CLYH:1000127 ! part of polyp colony
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000129
name: stolon growth tip
def: "Growing tip of a stolon." []
relationship: BFO:0000050 CLYH:1000128 ! part of stolon
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000130
name: stolon mesoglea
def: "Mesoglea layer between the inner and outer layers of the stolon." []
is_a: CLYH:1000158 ! mesoglea
relationship: BFO:0000050 CLYH:1000128 ! part of stolon
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000131
name: stolon body
def: "Segments of the stolon between the bases of the polyps, excluding the growing tip." []
relationship: BFO:0000050 CLYH:1000128 ! part of stolon
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000132
name: stolon ectoderm
def: "Outer layer within the stolon." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000128 ! part of stolon
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000133
name: stolon endoderm
def: "Inner layer within the stolon." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000128 ! part of stolon
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000134
name: gonozoid
def: "Polyp specialised for production of medusa by budding." []
relationship: BFO:0000050 CLYH:1000127 ! part of polyp colony
relationship: RO:0002202 CLYH:1000128 ! develops from stolon
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000135
name: gonozoid cap
def: "Structure that closes the distal end of the gonozoid." []
relationship: BFO:0000050 CLYH:1000134 ! part of gonozoid
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000136
name: gonozoid central tube
def: "Tubular structure comprising inner and outer layers at the centre of the gonozoid." []
relationship: BFO:0000050 CLYH:1000134 ! part of gonozoid
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000137
name: gonozoid ectoderm
def: "Outer layer of the gonozoid including central tube and developing buds." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000134 ! part of gonozoid
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000138
name: gonozoid endoderm
def: "Inner layer of the gonozoid including central tube and developing buds." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000134 ! part of gonozoid
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000139
name: epithelium covering buds
def: "Epithelial cell layer positioned between the developing medusa buds and the theca of the gonozoid." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000134 ! part of gonozoid
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000140
name: medusa bud
def: "Outgrowth of the gonozoid central tube, within which medusa structures develop." []
relationship: BFO:0000050 CLYH:1000134 ! part of gonozoid
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000141
name: early medusa bud
def: "Outgrowth of the gonozoid central tube, comprising entocodon, endoderm and ectoderm tissue layers." []
is_a: CLYH:1000140 ! medusa bud

[Term]
id: CLYH:1000142
name: mid medusa bud
def: "Bud on the side of the gonozoid central tube, in which all medusa structures are present but not yet expanded to final proportions." []
is_a: CLYH:1000140 ! medusa bud

[Term]
id: CLYH:1000143
name: late medusa bud
def: "Bud on the side of the gonozoid central tube, containing medusa structures with same proportions as newly released medusa." []
is_a: CLYH:1000140 ! medusa bud

[Term]
id: CLYH:1000144
name: entocodon
def: "Group of cells between the inner and outer layers of the early medusa bud." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000140 ! part of medusa bud
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000145
name: developing manubrium
def: "Developing manubrium within the medusa bud." []
is_a: CLYH:1000187 ! manubrium
relationship: BFO:0000050 CLYH:1000140 ! part of medusa bud
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000146
name: developing tentacle bulbs
def: "Developing tentacle bud within the medusa bud." []
is_a: CLYH:1000168 ! medusa tentacle system
relationship: BFO:0000050 CLYH:1000140 ! part of medusa bud
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000147
name: developing radial canal
def: "Developing radial canal within the medusa bud." []
is_a: CLYH:1000182 ! radial canal
relationship: BFO:0000050 CLYH:1000140 ! part of medusa bud
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000148
name: developing striated muscle
def: "Developing striated muscle within the medusa bud." []
is_a: CLYH:1000124 ! striated muscle cell
relationship: BFO:0000050 CLYH:1000140 ! part of medusa bud
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000149
name: developing circular canal
def: "Developing circular canal within the medusa bud." []
is_a: CLYH:1000183 ! circular canal
relationship: BFO:0000050 CLYH:1000140 ! part of medusa bud
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000150
name: gastrozoid
def: "Polyp specialised for catching prey and digesting." []
synonym: "hydranth" EXACT []
relationship: BFO:0000050 CLYH:1000127 ! part of polyp colony
relationship: RO:0002202 CLYH:1000128 ! develops from stolon
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000151
name: gastrozoid tentacle
def: "Tentacle surrounding the gastrozoid mouth." []
is_a: CLYH:1000005 ! tentacle
relationship: BFO:0000050 CLYH:1000150 ! part of gastrozoid
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000152
name: gastrozoid mouth
def: "Mouth of the gastrozoid." []
is_a: CLYH:1000003 ! mouth
relationship: BFO:0000050 CLYH:1000150 ! part of gastrozoid

[Term]
id: CLYH:1000153
name: matrix
is_a: UBERON:0000061 ! anatomical structure

[Term]
id: CLYH:1000154
name: theca
def: "Chitinous acellular layer surronding and protecting the polyps." []
is_a: CLYH:1000153 ! matrix
relationship: BFO:0000050 CLYH:1000127 ! part of polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000155
name: gonotheca
def: "Chitinous acellular layer surronding the gonozoid." []
is_a: CLYH:1000154 ! theca
relationship: BFO:0000050 CLYH:1000134 ! part of gonozoid

[Term]
id: CLYH:1000156
name: stolon perisarc
def: "Chitinous acellular layer surronding the stolon." []
is_a: CLYH:1000154 ! theca
relationship: BFO:0000050 CLYH:1000128 ! part of stolon

[Term]
id: CLYH:1000157
name: hydrotheca
def: "Chitinous acellular layer surronding the gastrozoid." []
is_a: CLYH:1000154 ! theca
relationship: BFO:0000050 CLYH:1000150 ! part of gastrozoid

[Term]
id: CLYH:1000158
name: mesoglea
def: "Jelly-like layer between epithelial layer. The mesoglea is mostly acellular and composed of extracellular matrix." []
is_a: CLYH:1000153 ! matrix

[Term]
id: CLYH:1000159
name: gonozoid mesoglea
def: "Mesoglea layer between the inner and outer tissue layers of the gonozoid central tube." []
is_a: CLYH:1000158 ! mesoglea
relationship: BFO:0000050 CLYH:1000134 ! part of gonozoid
relationship: RO:0002202 CLYH:1000127 ! develops from polyp colony
relationship: RO:0002488 CLYH:0000049 ! existence starts during colony phase
relationship: RO:0002492 CLYH:0000059 ! existence ends during medusa phase

[Term]
id: CLYH:1000160
name: medusa
def: "Swimming pelagic stage of the Clytia hemisphaerica life cycle." []
is_a: CLYH:1000001 ! multicellular organism
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000161
name: umbrella
def: "Dome-shaped part of the medusa stage." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000160 ! part of medusa
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000162
name: exumbrella
def: "Outer layer of the umbrella." []
relationship: BFO:0000050 CLYH:1000161 ! part of umbrella
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000163
name: subumbrella
def: "Inner layers of the umbrella." []
relationship: BFO:0000050 CLYH:1000161 ! part of umbrella
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000164
name: subumbrella endodermal plate
def: "Inner layer of the subumbrella in direct contact with the thick mesoglea layer of the medusa." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000163 ! part of subumbrella
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000165
name: thick mesoglea layer of the umbrella
def: "Thick mesoglea layer of the umbrella forming the bulk of the umbrella." []
is_a: CLYH:1000158 ! mesoglea
relationship: BFO:0000050 CLYH:1000160 ! part of medusa
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000166
name: bell margin
def: "Outer border of the umbrella." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000161 ! part of umbrella
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000167
name: statocyst
def: "Sensory structure of the medusa, located on the bell margin, consisting of a sensory vesicle containing statoliths." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000166 ! part of bell margin
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000168
name: medusa tentacle system
def: "Medusa tentacle system comprising tentacles, tentacle bulbs and tentacle buds." []
is_a: CLYH:1000004 ! tentacle system
relationship: BFO:0000050 CLYH:1000166 ! part of bell margin
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000169
name: medusa tentacle bud
def: "Initial stage of tentacle bulb formation." []
relationship: BFO:0000050 CLYH:1000168 ! part of medusa tentacle system
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000170
name: medusa tentacle bulb
def: "Swollen structure producing the tentacle and connecting the bell margin to the tentacle." []
relationship: BFO:0000050 CLYH:1000168 ! part of medusa tentacle system
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000171
name: nematogenic ectoderm of the bulb
def: "Cresent-shaped nematogenic area of the tentacle bulb, located on the oral side of the bulb outer layer." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000170 ! part of medusa tentacle bulb
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000172
name: non-nematogenic ectoderm of the bulb
def: "V-shaped non-nematogenic ectodermal area of the tentacle bulb, located on the aboral side of the bulb." []
synonym: "non-nematogenic epidermis of the bulb" EXACT []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000170 ! part of medusa tentacle bulb
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000173
name: tentacle bulb endoderm
def: "Inner layer of the medusa tentacle bulb." []
synonym: "tentacle bulb gastrodermis" EXACT []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000170 ! part of medusa tentacle bulb
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000174
name: medusa tentacle
def: "Tentacle of the medusa not including the tentacle bulb." []
is_a: CLYH:1000005 ! tentacle
relationship: BFO:0000050 CLYH:1000168 ! part of medusa tentacle system
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000175
name: primary medusa tentacle
def: "Four first medusa tentacles of the newly hatched medusa, connected to both radial and circular canals." []
is_a: CLYH:1000174 ! medusa tentacle

[Term]
id: CLYH:1000176
name: secondary medusa tentacle
def: "Medusa tentacle generated after medusa hatching and connected to the circular but not to the radial canal." []
is_a: CLYH:1000174 ! medusa tentacle
relationship: RO:0002202 CLYH:1000160 ! develops from medusa
relationship: RO:0002488 CLYH:0000066 ! existence starts during 8-bulb medusa stage

[Term]
id: CLYH:1000177
name: medusa tentacle ectoderm
def: "Outer layer of the medusa tentacle." []
synonym: "medusa tentacle epidermis" EXACT []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000174 ! part of medusa tentacle
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000178
name: medusa tentacle endoderm 
def: "Inner layer of the medusa tentacle." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000174 ! part of medusa tentacle
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000179
name: velum
def: "A muscular flap of tissue surrounding the margin of the bell." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000166 ! part of bell margin
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000180
name: inner layer of the velum
def: "Inner layer of the velum." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000179 ! part of velum
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000181
name: outerlater of the velum
def: "Outer layer of the velum." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000179 ! part of velum
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000182
name: radial canal
def: "Canal connecting the manubrium with the bell margin." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000160 ! part of medusa
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000183
name: circular canal
def: "Canal running along the bell margin." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000166 ! part of bell margin
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000184
name: nerve ring
def: "Concentration of nerve cell bodies and projections running around the margin of the bell." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000166 ! part of bell margin
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000185
name: inner nerve ring
def: "Nerve ring located closest to the centre of the medusa." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000184 ! part of nerve ring
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000186
name: outer nerve ring
def: "Nerve ring located farest to the centre of the medusa." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000184 ! part of nerve ring
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000187
name: manubrium
def: "Central structure of the medusa bearing the mouth and performing extracellular digestion." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000160 ! part of medusa
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000188
name: medusa mouth
def: "Medusa mouth as part of the manubrium." []
is_a: CLYH:1000003 ! mouth
relationship: BFO:0000050 CLYH:1000187 ! part of manubrium
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000189
name: manubrium roof
def: "Inner layer of the manubrium opposite to the mouth and in direct contact with the thick mesoglea layer of the medusa." []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000187 ! part of manubrium
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000190
name: manubrium ectoderm
def: "Outer layer of the manubrium." []
synonym: "manubrium epidermis" EXACT []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000187 ! part of manubrium
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000191
name: manubrium endoderm
def: "Inner digestive layer of the manubrium." []
synonym: "manubrium gastrodermis" EXACT []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000187 ! part of manubrium
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000192
name: gonad
def: "Reproductive organ of the medusa." []
is_a: UBERON:0000061 ! anatomical structure
relationship: BFO:0000050 CLYH:1000160 ! part of medusa
relationship: RO:0002202 CLYH:1000140 ! develops from medusa bud
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000193
name: gonad ectoderm
def: "Outer layer of the gonad." []
synonym: "gonad epidermis" EXACT []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000192 ! part of gonad
relationship: RO:0002202 CLYH:1000160 ! develops from medusa
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: CLYH:1000194
name: gonad endoderm
def: "Inner layer of the gonad." []
synonym: "gonad gastrodermis" EXACT []
is_a: CLYH:1000006 ! tissue layer
relationship: BFO:0000050 CLYH:1000192 ! part of gonad
relationship: RO:0002202 CLYH:1000160 ! develops from medusa
relationship: RO:0002488 CLYH:0000065 ! existence starts during 4-bulb medusa stage

[Term]
id: GO:0005575
name: cellular component
relationship: BFO:0000050 CL:0000000 ! part of cell

[Term]
id: GO:0005938
name: cell cortex
is_a: GO:0005575 ! cellular component

[Term]
id: UBERON:0000061
name: anatomical structure

[Term]
id: UBERON:0000105
name: life cycle stage

[Typedef]
id: BFO:0000050
name: part of

[Typedef]
id: RO:0002087
name: immediately preceded by

[Typedef]
id: RO:0002202
name: develops from

[Typedef]
id: RO:0002488
name: existence starts during

[Typedef]
id: RO:0002492
name: existence ends during