An alternative term used by the ISA tools project (http://isa-tools.org).
Requested by Alejandra Gonzalez-Beltran
https://sourceforge.net/tracker/?func=detail&aid=3603413&group_id=177891&atid=886178
Person: Alejandra Gonzalez-Beltran
Person: Philippe Rocca-Serra
ISA tools project (http://isa-tools.org)
ISA alternative term
An alternative term used by the IEDB.
PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters
IEDB
IEDB alternative term
BFO:0000050
external
part_of
part of
BFO:0000051
chebi_ontology
external
false
has_part
has part
BFO:0000066
external
occurs_in
occurs in
aggregate of
aggregate_of
http://purl.obolibrary.org/obo/omrse.owl
is aggregate of
c-ppart-of_at
properContinuantPartOfAt
b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001])
Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'proper part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'proper part of continuant@en(x,y,t)'.
http://purl.obolibrary.org/obo/bfo.owl
(iff (properContinuantPartOfAt a b t) (and (continuantPartOfAt a b t) (not (= a b)))) // axiom label in BFO2 CLIF: [004-001]
proper part of continuant at all times
c-part-of_at
continuantPartOfAt
Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
[copied from inverse property 'has continuant part at all times that part exists'] forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t)
Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'part of continuant@en(x,y,t)'.
BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
BFO2 Reference: continuant
BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
[copied from inverse property 'has continuant part at all times that part exists'] This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times'
http://purl.obolibrary.org/obo/bfo.owl
b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001])
continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002])
continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001])
continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001])
continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001])
if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002])
(forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002]
(forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002]
(forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001]
(forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001]
(forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001]
(forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001]
(iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001]
part of continuant at all times
c-has-part-object_at
[copied from inverse property 'part of continuant at all times'] Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
[copied from inverse property 'part of continuant at all times'] the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t)
This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times'
[copied from inverse property 'part of continuant at all times'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'part of continuant@en(x,y,t)'.
[copied from inverse property 'part of continuant at all times'] BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
[copied from inverse property 'part of continuant at all times'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
[copied from inverse property 'part of continuant at all times'] BFO2 Reference: continuant
[copied from inverse property 'part of continuant at all times'] BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
http://purl.obolibrary.org/obo/bfo.owl
[copied from inverse property 'part of continuant at all times'] b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
has continuant part at all times that part exists
has specified input
has specified output
Note: this will end up being a subproperty of has-characteristic when we add it, TBD depends on discussion of whether has-characteristic is functional
has quality
has part
has participant
occurs in
part of
enabled by
concretizes
intended to realize
executes
realizes
has characteristic
https://github.com/oborel/obo-relations/pull/284
http://purl.obolibrary.org/obo/IAO_0000136
is about
A duck swimming in a pond is partially surrounded by air and partially surrounded by water.
x partially_surrounded_by y if and only if (1) x is adjacent to y and for the region r that is adjacent to x, r partially overlaps y (2) the shared boundary between x and y occupies a non-trivial proportion of the outermost boundary of x
Definition modified from 'surrounded by'.
partially_surrounded_by
A relation between a process and a disposition such that the existence of the disposition is caused by the execution of the process.
Consider ceding to RO
cjm
2018-11-03T20:58:13Z
generates
is in aggregate
GOREL:0002003
external
results_in_distribution_of
results_in_distribution_of
GOREL:0002004
external
results_in_fission_of
results_in_fission_of
GOREL:0002005
external
results_in_fusion_of
results_in_fusion_of
The relation between the conclusion "Gene tpbA is involved in EPS production" and the data items produced using two sets of organisms, one being a tpbA knockout, the other being tpbA wildtype tested in polysacharide production assays and analyzed using an ANOVA.
The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process
OBI
OBI
Philly 2011 workshop
is_supported_by_data
has_specified_input
see is_input_of example_of_usage
A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works.
PERSON: Alan Ruttenberg
PERSON: Bjoern Peters
PERSON: Larry Hunter
PERSON: Melanie Coutot
has_specified_input
is_specified_input_of
some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay
A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
Alan Ruttenberg
PERSON:Bjoern Peters
is_specified_input_of
has_specified_output
A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
PERSON: Alan Ruttenberg
PERSON: Bjoern Peters
PERSON: Larry Hunter
PERSON: Melanie Courtot
has_specified_output
is_specified_output_of
A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
Alan Ruttenberg
PERSON:Bjoern Peters
is_specified_output_of
achieves_planned_objective
A cell sorting process achieves the objective specification 'material separation objective'
This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.
BP, AR, PPPB branch
PPPB branch derived
modified according to email thread from 1/23/09 in accordince with DT and PPPB branch
achieves_planned_objective
has grain
the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car.
Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. Definition take from the definition of granular parthood in the cited paper. Needs work to put into standard form
PERSON: Alan Ruttenberg
PAPER: Granularity, scale and collectivity: When size does and does not matter, Alan Rector, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349
has grain
objective_achieved_by
This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.
OBI
OBI
objective_achieved_by
A relation between an information content entity and a value specification that specifies its value.
PERSON: James A. Overton
OBI
has value specification
RO:0000053
external
bearer_of
bearer of
RO:0000057
external
has_participant
has participant
RO:0000087
chebi_ontology
false
false
has_role
has role
RO:0002211
external
regulates
regulates
regulates (processual)
RO:0002212
external
negatively_regulates
negatively regulates
RO:0002213
external
positively_regulates
positively regulates
RO:0002215
external
capable_of
capable of
RO:0002216
external
capable_of_part_of
capable of part of
surrounded by
RO:0002224
external
starts_with
starts with
RO:0002230
external
ends_with
ends with
RO:0002233
external
has_input
has input
RO:0002234
external
has_output
has output
RO:0002295
external
results_in_developmental_progression_of
results in developmental progression of
RO:0002296
external
results_in_development_of
results in development of
RO:0002297
external
results_in_formation_of
results in formation of
RO:0002298
external
results_in_morphogenesis_of
results in morphogenesis of
RO:0002313
external
transports_or_maintains_localization_of
transports or maintains localization of
RO:0002315
external
results_in_acquisition_of_features_of
results in acquisition of features of
RO:0002338
external
has_target_start_location
has target start location
RO:0002339
external
has_target_end_location
has target end location
RO:0002341
external
results_in_transport_along
results in transport along
RO:0002342
external
results_in_transport_across
results in transport across
RO:0002344
external
results_in_transport_to_from_or_in
results in transport to from or in
RO:0002578
external
directly_regulates
directly regulates
RO:0002588
external
results_in_assembly_of
results_in_assembly_of
RO:0002590
external
results_in_disassembly_of
results_in_disassembly_of
RO:0002592
external
results_in_organization_of
results_in_organization_of
RO:0002608
external
process_has_causal_agent
process has causal agent
RO:0004007
external
has_primary_input_or_output
has primary input or output
RO:0004008
external
has_primary_output
has primary output
RO:0004009
external
has_primary_input
has primary input
chebi_ontology
false
false
has functional parent
chebi_ontology
false
false
has parent hydride
chebi_ontology
true
false
is conjugate acid of
chebi_ontology
true
false
is conjugate base of
chebi_ontology
false
false
is substituent group from
chebi_ontology
true
is tautomer of
http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)
lacks_plasma_membrane_part
has number of atomic nuclei
entity
Entity
Julius Caesar
Verdi’s Requiem
the Second World War
your body mass index
BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81
Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])
entity
Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
per discussion with Barry Smith
An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])
continuant
Continuant
An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240
Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]
continuant
Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]
ic
IndependentContinuant
a chair
a heart
a leg
a molecule
a spatial region
an atom
an orchestra.
an organism
the bottom right portion of a human torso
the interior of your mouth
A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
independent continuant
b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
object-aggregate
ObjectAggregate
a collection of cells in a blood biobank.
a swarm of bees is an aggregate of members who are linked together through natural bonds
a symphony orchestra
an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team)
defined by fiat: the aggregate of members of an organization
defined through physical attachment: the aggregate of atoms in a lump of granite
defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container
defined via attributive delimitations such as: the patients in this hospital
the aggregate of bearings in a constant velocity axle joint
the aggregate of blood cells in your body
the nitrogen atoms in the atmosphere
the restaurants in Palo Alto
your collection of Meissen ceramic plates.
An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects
BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee).
ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.
b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])
(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004]
object aggregate
An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects
An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects
ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.
b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])
(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004]
gdc
GenericallyDependentContinuant
The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity.
the pdf file on your laptop, the pdf file that is a copy thereof on my laptop
the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule.
A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.
b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001]
generically dependent continuant
b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001]
Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa.
Wikipedia:Volatile_organic_compound
chebi_ontology
VOC
VOCs
volatile organic compounds
volatile organic compound
VOC
ChEBI
VOCs
ChEBI
volatile organic compounds
ChEBI
An alkanesulfonate in which the carbon at position 1 is attached to R, which can represent hydrogens, a carbon chain, or other groups.
-1
CH2O3SR
94.091
93.97246
C(S([O-])(=O)=O)*
CHEBI:22318
MetaCyc:Alkanesulfonates
chebi_ontology
alkanesulfonate oxoanions
alkanesulfonates
an alkanesulfonate
alkanesulfonate oxoanion
alkanesulfonate oxoanions
ChEBI
alkanesulfonates
ChEBI
an alkanesulfonate
UniProt
An organic cation obtained by protonation of the amino group of any tertiary amino compound.
+1
HNR3
15.015
15.01090
[NH+](*)(*)*
chebi_ontology
a tertiary amine
tertiary amine(1+)
tertiary ammonium ions
tertiary ammonium ion
a tertiary amine
UniProt
tertiary amine(1+)
ChEBI
tertiary ammonium ions
ChEBI
A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.
Wikipedia:Mineral_acid
chebi_ontology
inorganic acids
mineral acid
mineral acids
inorganic acid
inorganic acids
ChEBI
mineral acid
ChEBI
mineral acids
ChEBI
Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa).
Wikipedia:https://en.wikipedia.org/wiki/Gas
chebi_ontology
gas molecular entities
gaseous molecular entities
gaseous molecular entity
gas molecular entity
gas molecular entities
ChEBI
gaseous molecular entities
ChEBI
gaseous molecular entity
ChEBI
-1
CH2NO2
InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1
KXDHJXZQYSOELW-UHFFFAOYSA-M
60.03212
60.00910
NC([O-])=O
Beilstein:3903503
CAS:302-11-4
Gmelin:239604
carbamate
chebi_ontology
Carbamat
Karbamat
carbamate ion
carbamic acid, ion(1-)
carbamate
Beilstein:3903503
Beilstein
CAS:302-11-4
ChemIDplus
Gmelin:239604
Gmelin
carbamate
IUPAC
carbamate
UniProt
Carbamat
ChEBI
Karbamat
ChEBI
carbamate ion
ChemIDplus
carbamic acid, ion(1-)
ChemIDplus
A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.
CHEBI:13699
CHEBI:2377
KEGG:C00028
KEGG:C16722
Acceptor
chebi_ontology
A
Akzeptor
Hydrogen-acceptor
Oxidized donor
accepteur
acceptor
Acceptor
KEGG_COMPOUND
A
KEGG_COMPOUND
Akzeptor
ChEBI
Hydrogen-acceptor
KEGG_COMPOUND
Oxidized donor
KEGG_COMPOUND
accepteur
ChEBI
An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.
0
H3N
InChI=1S/H3N/h1H3
QGZKDVFQNNGYKY-UHFFFAOYSA-N
17.03056
17.02655
[H]N([H])[H]
CHEBI:13405
CHEBI:13406
CHEBI:13407
CHEBI:13771
CHEBI:22533
CHEBI:44269
CHEBI:44284
CHEBI:44404
CHEBI:7434
Beilstein:3587154
CAS:7664-41-7
Drug_Central:4625
Gmelin:79
HMDB:HMDB0000051
KEGG:C00014
KEGG:D02916
KNApSAcK:C00007267
MetaCyc:AMMONIA
MolBase:930
PDBeChem:NH3
PMID:110589
PMID:11139349
PMID:11540049
PMID:11746427
PMID:11783653
PMID:13753780
PMID:14663195
PMID:15092448
PMID:15094021
PMID:15554424
PMID:15969015
PMID:16008360
PMID:16050680
PMID:16348008
PMID:16349403
PMID:16614889
PMID:16664306
PMID:16842901
PMID:17025297
PMID:17439666
PMID:17569513
PMID:17737668
PMID:18670398
PMID:22002069
PMID:22081570
PMID:22088435
PMID:22100291
PMID:22130175
PMID:22150211
PMID:22240068
PMID:22290316
PMID:22342082
PMID:22385337
PMID:22443779
PMID:22560242
Reaxys:3587154
Wikipedia:Ammonia
AMMONIA
Ammonia
ammonia
azane
chebi_ontology
Ammoniak
NH3
R-717
[NH3]
ammoniac
amoniaco
spirit of hartshorn
ammonia
PMID:16842901
Europe PMC
PMID:17025297
Europe PMC
PMID:17439666
Europe PMC
PMID:17569513
Europe PMC
PMID:17737668
Europe PMC
PMID:18670398
Europe PMC
PMID:22002069
Europe PMC
PMID:22081570
Europe PMC
PMID:22088435
Europe PMC
PMID:22100291
Europe PMC
PMID:22130175
Europe PMC
PMID:22150211
Europe PMC
PMID:22240068
Europe PMC
PMID:22290316
Europe PMC
PMID:22342082
Europe PMC
PMID:22385337
Europe PMC
PMID:22443779
Europe PMC
PMID:22560242
Europe PMC
Reaxys:3587154
Reaxys
AMMONIA
PDBeChem
Ammonia
KEGG_COMPOUND
ammonia
IUPAC
azane
IUPAC
Ammoniak
ChemIDplus
NH3
IUPAC
NH3
KEGG_COMPOUND
NH3
UniProt
R-717
ChEBI
[NH3]
MolBase
ammoniac
ChEBI
amoniaco
ChEBI
spirit of hartshorn
ChemIDplus
Beilstein:3587154
Beilstein
CAS:7664-41-7
ChemIDplus
CAS:7664-41-7
KEGG COMPOUND
CAS:7664-41-7
NIST Chemistry WebBook
Drug_Central:4625
DrugCentral
Gmelin:79
Gmelin
PMID:110589
Europe PMC
PMID:11139349
Europe PMC
PMID:11540049
Europe PMC
PMID:11746427
Europe PMC
PMID:11783653
Europe PMC
PMID:13753780
Europe PMC
PMID:14663195
Europe PMC
PMID:15092448
Europe PMC
PMID:15094021
Europe PMC
PMID:15554424
Europe PMC
PMID:15969015
Europe PMC
PMID:16008360
Europe PMC
PMID:16050680
Europe PMC
PMID:16348008
Europe PMC
PMID:16349403
Europe PMC
PMID:16614889
Europe PMC
PMID:16664306
Europe PMC
A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system.
0
C6H6
InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H
UHOVQNZJYSORNB-UHFFFAOYSA-N
78.11184
78.04695
c1ccccc1
CHEBI:13876
CHEBI:22703
CHEBI:3025
CHEBI:41187
Beilstein:969212
CAS:71-43-2
Gmelin:1671
HMDB:HMDB0001505
KEGG:C01407
PDBeChem:BNZ
PMID:11684179
PMID:11993966
PMID:12857942
PMID:14677922
PMID:15468289
PMID:15935818
PMID:16161967
PMID:17373369
PMID:18072742
PMID:18407866
PMID:18409691
PMID:18836923
PMID:19228219
PMID:21325737
PMID:23088855
PMID:23222815
PMID:23534829
PMID:6353911
PMID:8124204
Reaxys:969212
UM-BBD_compID:c0142
Wikipedia:Benzene
BENZENE
Benzene
benzene
chebi_ontology
Benzen
Benzine
Benzol
Bicarburet of hydrogen
Coal naphtha
Mineral naphtha
Phene
Pyrobenzol
Pyrobenzole
[6]annulene
benzole
cyclohexatriene
phenyl hydride
benzene
Beilstein:969212
Beilstein
CAS:71-43-2
ChemIDplus
CAS:71-43-2
KEGG COMPOUND
CAS:71-43-2
NIST Chemistry WebBook
Gmelin:1671
Gmelin
PMID:11684179
Europe PMC
PMID:11993966
Europe PMC
PMID:12857942
Europe PMC
PMID:14677922
Europe PMC
PMID:15468289
Europe PMC
PMID:15935818
Europe PMC
PMID:16161967
Europe PMC
PMID:17373369
Europe PMC
PMID:18072742
Europe PMC
PMID:18407866
Europe PMC
PMID:18409691
Europe PMC
PMID:18836923
Europe PMC
PMID:19228219
Europe PMC
PMID:21325737
Europe PMC
PMID:23088855
Europe PMC
PMID:23222815
Europe PMC
PMID:23534829
Europe PMC
PMID:6353911
Europe PMC
PMID:8124204
Europe PMC
Reaxys:969212
Reaxys
UM-BBD_compID:c0142
UM-BBD
BENZENE
PDBeChem
Benzene
KEGG_COMPOUND
benzene
ChEBI
benzene
IUPAC
benzene
UniProt
Benzen
IUPAC
Benzine
UM-BBD
Benzol
ChemIDplus
Bicarburet of hydrogen
ChemIDplus
Coal naphtha
ChemIDplus
Mineral naphtha
ChemIDplus
Phene
ChemIDplus
Pyrobenzol
ChemIDplus
Pyrobenzole
ChemIDplus
[6]annulene
NIST_Chemistry_WebBook
benzole
NIST_Chemistry_WebBook
cyclohexatriene
UM-BBD
phenyl hydride
UM-BBD
-1
HO3S
InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1
LSNNMFCWUKXFEE-UHFFFAOYSA-M
81.07214
80.96519
OS([O-])=O
CHEBI:13367
CHEBI:5598
CAS:15181-46-1
Gmelin:1455
KEGG:C11481
PDBeChem:SO3
hydrogen(trioxidosulfate)(1-)
hydrogensulfite(1-)
hydrogentrioxosulfate(1-)
hydrogentrioxosulfate(IV)
hydroxidodioxidosulfate(1-)
monohydrogentrioxosulfate
chebi_ontology
Bisulfite
HSO3(-)
HSO3-
Hydrogen sulfite
[SO2(OH)](-)
bisulfite
bisulphite
hydrogen sulfite(1-)
hydrosulfite anion
hydrogensulfite
CAS:15181-46-1
ChemIDplus
CAS:15181-46-1
KEGG COMPOUND
Gmelin:1455
Gmelin
hydrogen(trioxidosulfate)(1-)
IUPAC
hydrogensulfite(1-)
IUPAC
hydrogentrioxosulfate(1-)
IUPAC
hydrogentrioxosulfate(IV)
IUPAC
hydroxidodioxidosulfate(1-)
IUPAC
monohydrogentrioxosulfate
IUPAC
Bisulfite
KEGG_COMPOUND
HSO3(-)
IUPAC
HSO3-
KEGG_COMPOUND
Hydrogen sulfite
KEGG_COMPOUND
[SO2(OH)](-)
IUPAC
bisulfite
ChemIDplus
bisulphite
ChemIDplus
hydrogen sulfite(1-)
ChemIDplus
hydrosulfite anion
ChemIDplus
A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3).
-2
O3S
InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-2
LSNNMFCWUKXFEE-UHFFFAOYSA-L
80.06420
79.95791
[O-]S([O-])=O
CHEBI:15139
CHEBI:45548
CAS:14265-45-3
Gmelin:1449
PDBeChem:SO3
sulfite
trioxidosulfate(2-)
trioxosulfate(2-)
trioxosulfate(IV)
chebi_ontology
SO3
SO3(2-)
SULFITE ION
[SO3](2-)
sulphite
sulfite
CAS:14265-45-3
ChemIDplus
Gmelin:1449
Gmelin
sulfite
IUPAC
sulfite
UniProt
trioxidosulfate(2-)
IUPAC
trioxosulfate(2-)
IUPAC
trioxosulfate(IV)
IUPAC
SO3
ChEBI
SO3(2-)
IUPAC
SULFITE ION
PDBeChem
[SO3](2-)
IUPAC
sulphite
ChEBI
SO:0000253
A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.
CHEBI:14202
CHEBI:4697
KEGG:C01351
Donor
chebi_ontology
Donator
donneur
donor
Donor
KEGG_COMPOUND
Donator
ChEBI
donneur
ChEBI
SO:0000252
An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms.
0
CH3R
15.035
15.02348
C[*]
CHEBI:13435
CHEBI:22317
CHEBI:2576
KEGG:C01371
Alkane
alkane
alkanes
chebi_ontology
Alkan
RH
alcane
alcanes
alcano
alcanos
an alkane
alkane
Alkane
KEGG_COMPOUND
alkane
IUPAC
alkanes
IUPAC
Alkan
ChEBI
RH
KEGG_COMPOUND
alcane
IUPAC
alcanes
IUPAC
alcano
IUPAC
alcanos
IUPAC
an alkane
UniProt
An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids.
acyl group
alkanoyl
chebi_ontology
acyl groups
alkanoyl group
groupe acyle
acyl group
acyl group
IUPAC
alkanoyl
IUPAC
acyl groups
ChEBI
alkanoyl group
ChEBI
groupe acyle
IUPAC
A univalent group -CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom.
alkyl group
alkyl groups
chebi_ontology
groupe alkyle
grupo alquilo
grupos alquilo
alkyl group
alkyl group
IUPAC
alkyl groups
IUPAC
groupe alkyle
IUPAC
grupo alquilo
IUPAC
grupos alquilo
IUPAC
A monoatomic or polyatomic species having one or more elementary charges of the electron.
Anion
anion
chebi_ontology
Anionen
aniones
anions
anion
Anion
ChEBI
anion
ChEBI
anion
IUPAC
Anionen
ChEBI
aniones
ChEBI
anions
IUPAC
A monocarboxylic acid amide in which the amide linkage is bonded directly to an arene ring system.
chebi_ontology
arenecarboxamides
arenecarboxamide
arenecarboxamides
ChEBI
A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).
KEGG:C00701
Base
base
chebi_ontology
Base1
Base2
Basen
Nucleobase
bases
base
Base
ChEBI
base
ChEBI
base
IUPAC
Base1
KEGG_COMPOUND
Base2
KEGG_COMPOUND
Basen
ChEBI
Nucleobase
KEGG_COMPOUND
bases
ChEBI
chebi_ontology
benzamides
Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives.
chebi_ontology
benzenes
The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid.
0
CH2NO
44.03272
44.01364
*C(N)=O
PMID:24168430
carbamoyl
chebi_ontology
-C(O)NH2
-CONH2
aminocarbonyl
carbamyl
carbamyl group
carboxamide
carbamoyl group
PMID:24168430
Europe PMC
carbamoyl
IUPAC
-C(O)NH2
ChEBI
-CONH2
IUPAC
aminocarbonyl
IUPAC
carbamyl
ChEBI
carbamyl group
ChEBI
carboxamide
IUPAC
0
CO
28.01010
27.99491
O=C(*)*
carbonyl
carbonyl group
chebi_ontology
>C=O
carbonyl group
carbonyl
IUPAC
carbonyl group
ChEBI
carbonyl group
UniProt
>C=O
IUPAC
An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
Wikipedia:Cofactor_(biochemistry)
cofactor
cofactors
chebi_ontology
cofactor
cofactor
IUPAC
cofactors
IUPAC
copper molecular entity
chebi_ontology
copper compounds
copper molecular entities
copper molecular entity
copper molecular entity
ChEBI
copper compounds
ChEBI
copper molecular entities
ChEBI
Cu
63.546
62.92960
copper cation
chebi_ontology
Cu cation
copper cations
copper cation
copper cation
IUPAC
Cu cation
UniProt
copper cations
ChEBI
Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.
chebi_ontology
drugs
medicine
drug
drugs
ChEBI
medicine
ChEBI
chebi_ontology
monoatomic cations
monoatomic cation
monoatomic cations
ChEBI
A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
enzyme inhibitor
chebi_ontology
enzyme inhibitors
inhibidor enzimatico
inhibidores enzimaticos
inhibiteur enzymatique
inhibiteurs enzymatiques
enzyme inhibitor
enzyme inhibitor
IUPAC
enzyme inhibitors
ChEBI
inhibidor enzimatico
ChEBI
inhibidores enzimaticos
ChEBI
inhibiteur enzymatique
ChEBI
inhibiteurs enzymatiques
ChEBI
A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.
chemical entity
chebi_ontology
chemical entity
chemical entity
UniProt
A role played by the molecular entity or part thereof within a biological context.
chebi_ontology
biological function
biological role
biological function
ChEBI
A defined linked collection of atoms or a single atom within a molecular entity.
group
chebi_ontology
Gruppe
Rest
groupe
grupo
grupos
group
group
IUPAC
Gruppe
ChEBI
Rest
ChEBI
groupe
IUPAC
grupo
IUPAC
grupos
IUPAC
A cyclic compound having as ring members atoms of carbon and at least of one other element.
chebi_ontology
organic heterocycle
organic heterocyclic compounds
organic heterocyclic compound
organic heterocycle
ChEBI
organic heterocyclic compounds
ChEBI
A compound consisting of carbon and hydrogen only.
hydrocarbon
hydrocarbons
chebi_ontology
Kohlenwasserstoff
Kohlenwasserstoffe
hidrocarburo
hidrocarburos
hydrocarbure
hydrocarbon
hydrocarbon
IUPAC
hydrocarbons
IUPAC
Kohlenwasserstoff
ChEBI
Kohlenwasserstoffe
ChEBI
hidrocarburo
IUPAC
hidrocarburos
IUPAC
hydrocarbure
IUPAC
Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)).
chebi_ontology
hydroxides
A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
oxoacid
oxoacids
chebi_ontology
oxacids
oxiacids
oxo acid
oxy-acids
oxyacids
oxoacid
oxoacid
IUPAC
oxoacids
IUPAC
oxacids
ChEBI
oxiacids
ChEBI
oxo acid
ChEBI
oxy-acids
ChEBI
oxyacids
ChEBI
chebi_ontology
inorganic anions
inorganic anion
inorganic anions
ChEBI
A molecular entity that contains no carbon.
chebi_ontology
anorganische Verbindungen
inorganic compounds
inorganic entity
inorganic molecular entities
inorganics
inorganic molecular entity
anorganische Verbindungen
ChEBI
inorganic compounds
ChEBI
inorganic entity
ChEBI
inorganic molecular entities
ChEBI
inorganics
ChEBI
chebi_ontology
inorganic oxides
inorganic oxide
inorganic oxides
ChEBI
A salt is an assembly of cations and anions.
salt
chebi_ontology
Salz
Salze
ionic compound
ionic compounds
sal
sales
salts
sel
sels
salt
salt
IUPAC
Salz
ChEBI
Salze
ChEBI
ionic compound
ChEBI
ionic compounds
ChEBI
sal
ChEBI
sales
ChEBI
salts
ChEBI
sel
ChEBI
sels
ChEBI
chebi_ontology
organic salts
organisches Salz
organic salt
organic salts
ChEBI
organisches Salz
ChEBI
A molecular entity having a net electric charge.
Ion
ion
chebi_ontology
Ionen
iones
ions
ion
Ion
ChEBI
ion
ChEBI
ion
IUPAC
Ionen
ChEBI
iones
ChEBI
ions
ChEBI
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
CHEBI:26619
CHEBI:35220
metabolite
chebi_ontology
metabolites
primary metabolites
secondary metabolites
metabolite
metabolite
IUPAC
metabolites
ChEBI
primary metabolites
ChEBI
secondary metabolites
ChEBI
chebi_ontology
a metal cation
metal cations
metal cation
a metal cation
UniProt
metal cations
ChEBI
A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid.
-1
CH3O3S
InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)/p-1
AFVFQIVMOAPDHO-UHFFFAOYSA-M
95.09872
94.98084
CS([O-])(=O)=O
MetaCyc:CPD-3746
UM-BBD_compID:c0347
methanesulfonate
chebi_ontology
methylsulfonate
methanesulfonate
UM-BBD_compID:c0347
UM-BBD
methanesulfonate
IUPAC
methanesulfonate
UniProt
methylsulfonate
UM-BBD
Any polyatomic entity that is an electrically neutral entity consisting of more than one atom.
molecule
chebi_ontology
Molekuel
molecula
molecules
neutral molecular compounds
molecule
molecule
IUPAC
Molekuel
ChEBI
molecula
IUPAC
molecules
IUPAC
neutral molecular compounds
IUPAC
+1
0.00000
[*+]
chebi_ontology
monoatomic monocations
monovalent inorganic cations
monoatomic monocation
monoatomic monocations
ChEBI
monovalent inorganic cations
ChEBI
chebi_ontology
monoatomic polycations
multivalent inorganic cations
monoatomic polycation
monoatomic polycations
ChEBI
multivalent inorganic cations
ChEBI
0
N
14.007
14.00307
WebElements:N
nitrogen
chebi_ontology
7N
N
Stickstoff
azote
nitrogen
nitrogeno
nitrogen atom
nitrogen
IUPAC
7N
IUPAC
N
IUPAC
Stickstoff
ChEBI
azote
IUPAC
nitrogen
ChEBI
nitrogeno
ChEBI
nonmetal
chebi_ontology
Nichtmetall
Nichtmetalle
no metal
no metales
non-metal
non-metaux
nonmetal
nonmetals
nonmetal atom
nonmetal
IUPAC
Nichtmetall
ChEBI
Nichtmetalle
ChEBI
no metal
ChEBI
no metales
ChEBI
non-metal
ChEBI
non-metaux
ChEBI
nonmetal
ChEBI
nonmetals
ChEBI
chebi_ontology
organic heteromonocyclic compounds
organic heteromonocyclic compound
organic heteromonocyclic compounds
ChEBI
Any organic ion with a net negative charge.
chebi_ontology
organic anions
organic anion
organic anions
ChEBI
Any organic ion with a net positive charge.
chebi_ontology
organic cations
organic cation
organic cations
ChEBI
chebi_ontology
organic ions
organic ion
organic ions
ChEBI
An oxide is a chemical compound of oxygen with other chemical elements.
oxide
chebi_ontology
oxides
oxide
oxide
ChEBI
oxides
ChEBI
0
O
InChI=1S/O
QVGXLLKOCUKJST-UHFFFAOYSA-N
15.99940
15.99491
[O]
KEGG:C00007
WebElements:O
oxygen
chebi_ontology
8O
O
Sauerstoff
oxigeno
oxygen
oxygene
oxygen atom
oxygen
IUPAC
8O
IUPAC
O
IUPAC
Sauerstoff
ChEBI
oxigeno
ChEBI
oxygen
ChEBI
oxygene
ChEBI
oxygen molecular entity
chebi_ontology
oxygen molecular entities
oxygen molecular entity
oxygen molecular entity
ChEBI
oxygen molecular entities
ChEBI
chebi_ontology
piperazines
Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives.
chebi_ontology
pyridines
0
S
InChI=1S/S
NINIDFKCEFEMDL-UHFFFAOYSA-N
32.06600
31.97207
[S]
CAS:7704-34-9
KEGG:C00087
KEGG:D06527
PPDB:605
WebElements:S
sulfur
chebi_ontology
16S
Elemental sulfur
S
Schwefel
azufre
soufre
sulfur
sulphur
theion
sulfur atom
CAS:7704-34-9
ChemIDplus
CAS:7704-34-9
NIST Chemistry WebBook
sulfur
IUPAC
16S
IUPAC
Elemental sulfur
KEGG_COMPOUND
S
IUPAC
S
KEGG_COMPOUND
Schwefel
ChEBI
azufre
ChEBI
soufre
ChEBI
sulfur
ChEBI
sulfur
UniProt
sulphur
ChEBI
theion
IUPAC
sulfur molecular entity
chebi_ontology
sulfur molecular entities
sulfur molecular entity
sulfur molecular entity
ChEBI
sulfur molecular entities
ChEBI
Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
Wikipedia:Micronutrient
chebi_ontology
micronutrients
trace elements
micronutrient
micronutrients
ChEBI
trace elements
ChEBI
An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell.
transition element
chebi_ontology
Uebergangselement
Uebergangsmetalle
metal de transicion
metal de transition
metales de transicion
metaux de transition
transition element
transition elements
transition metal
transition metals
transition element atom
transition element
IUPAC
Uebergangselement
ChEBI
Uebergangsmetalle
ChEBI
metal de transicion
ChEBI
metal de transition
ChEBI
metales de transicion
ChEBI
metaux de transition
ChEBI
transition element
ChEBI
transition elements
ChEBI
transition metal
ChEBI
transition metals
ChEBI
+3
0.00000
[*+3]
chebi_ontology
monoatomic trications
trivalent inorganic cations
monoatomic trication
monoatomic trications
ChEBI
trivalent inorganic cations
ChEBI
A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid.
chebi_ontology
univalent acyl group
univalent carboacyl groups
univalent carboxylic acyl groups
univalent carboacyl group
univalent acyl group
ChEBI
univalent carboacyl groups
ChEBI
univalent carboxylic acyl groups
ChEBI
An alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl.
0
CH4O3S
InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)
AFVFQIVMOAPDHO-UHFFFAOYSA-N
96.10666
95.98812
CS(O)(=O)=O
CHEBI:6813
Beilstein:1446024
CAS:75-75-2
Gmelin:1681
KEGG:C11145
MetaCyc:CPD-3746
PMID:24304088
PMID:24593036
Reaxys:1446024
Wikipedia:Methanesulfonic_acid
Methanesulfonic acid
methanesulfonic acid
chebi_ontology
Methansulfonsaeure
methylsulfonic acid
methanesulfonic acid
Beilstein:1446024
Beilstein
CAS:75-75-2
ChemIDplus
CAS:75-75-2
KEGG COMPOUND
CAS:75-75-2
NIST Chemistry WebBook
Gmelin:1681
Gmelin
PMID:24304088
Europe PMC
PMID:24593036
Europe PMC
Reaxys:1446024
Reaxys
Methanesulfonic acid
KEGG_COMPOUND
methanesulfonic acid
IUPAC
Methansulfonsaeure
ChEBI
methylsulfonic acid
NIST_Chemistry_WebBook
0
C
InChI=1S/C
OKTJSMMVPCPJKN-UHFFFAOYSA-N
12.01070
12.00000
[C]
CHEBI:23009
CHEBI:3399
CAS:7440-44-0
KEGG:C06265
WebElements:C
carbon
chebi_ontology
6C
C
Carbon
Kohlenstoff
carbon
carbone
carbonium
carbono
carbon atom
CAS:7440-44-0
ChemIDplus
CAS:7440-44-0
KEGG COMPOUND
carbon
IUPAC
6C
IUPAC
C
IUPAC
C
KEGG_COMPOUND
Carbon
KEGG_COMPOUND
Kohlenstoff
ChEBI
carbon
ChEBI
carbone
ChEBI
carbonium
ChEBI
carbono
ChEBI
An aromatic amide that consists of benzene bearing a single carboxamido substituent. The parent of the class of benzamides.
0
C7H7NO
InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
KXDAEFPNCMNJSK-UHFFFAOYSA-N
121.13662
121.05276
NC(=O)c1ccccc1
CHEBI:22701
CHEBI:3021
CHEBI:46351
Beilstein:385876
CAS:55-21-0
HMDB:HMDB0004461
KEGG:C09815
PMID:20133863
Reaxys:385876
UM-BBD_compID:c0368
Wikipedia:Benzamide
Benzamide
benzamide
chebi_ontology
Benzenecarboxamide
Benzoic acid amide
Benzoylamide
PhC(=O)NH2
PhC(O)NH2
Phenylcarboxamide
Phenylcarboxyamide
benzamide
Beilstein:385876
Beilstein
CAS:55-21-0
ChemIDplus
CAS:55-21-0
KEGG COMPOUND
CAS:55-21-0
NIST Chemistry WebBook
PMID:20133863
Europe PMC
Reaxys:385876
Reaxys
UM-BBD_compID:c0368
UM-BBD
Benzamide
KEGG_COMPOUND
benzamide
IUPAC
Benzenecarboxamide
ChemIDplus
Benzoic acid amide
ChemIDplus
Benzoylamide
ChemIDplus
PhC(=O)NH2
ChEBI
PhC(O)NH2
ChEBI
Phenylcarboxamide
ChemIDplus
Phenylcarboxyamide
ChemIDplus
A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised.
0
CH3NO2
InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)
KXDHJXZQYSOELW-UHFFFAOYSA-N
61.04006
61.01638
NC(O)=O
CHEBI:22504
CHEBI:23002
CHEBI:3386
CHEBI:44573
Beilstein:1734754
CAS:463-77-4
DrugBank:DB04261
Gmelin:130345
KEGG:C01563
PDBeChem:OUT
Wikipedia:Carbamic_acid
CARBAMIC ACID
Carbamic acid
carbamic acid
chebi_ontology
Aminoameisensaeure
Aminoformic acid
Carbamate
Carbamidsaeure
carbamic acid
Beilstein:1734754
Beilstein
CAS:463-77-4
ChemIDplus
CAS:463-77-4
KEGG COMPOUND
Gmelin:130345
Gmelin
CARBAMIC ACID
PDBeChem
Carbamic acid
KEGG_COMPOUND
carbamic acid
IUPAC
Aminoameisensaeure
ChEBI
Aminoformic acid
KEGG_COMPOUND
Carbamate
KEGG_COMPOUND
Carbamidsaeure
ChEBI
0
Cu
InChI=1S/Cu
RYGMFSIKBFXOCR-UHFFFAOYSA-N
63.54600
62.92960
[Cu]
CHEBI:23376
CHEBI:3874
CAS:7440-50-8
Gmelin:16269
KEGG:C00070
WebElements:Cu
copper
chebi_ontology
29Cu
Copper
Cu
Kupfer
cobre
copper
cuivre
cuprum
copper atom
CAS:7440-50-8
ChemIDplus
CAS:7440-50-8
KEGG COMPOUND
Gmelin:16269
Gmelin
copper
IUPAC
29Cu
IUPAC
Copper
KEGG_COMPOUND
Cu
ChEBI
Cu
IUPAC
Kupfer
ChEBI
cobre
ChEBI
copper
ChEBI
cuivre
ChEBI
cuprum
IUPAC
An onium cation obtained by protonation of ammonia.
+1
H4N
InChI=1S/H3N/h1H3/p+1
QGZKDVFQNNGYKY-UHFFFAOYSA-O
18.03850
18.03383
[H][N+]([H])([H])[H]
CHEBI:22534
CHEBI:49783
CHEBI:7435
CAS:14798-03-9
Gmelin:84
KEGG:C01342
MetaCyc:AMMONIUM
MolBase:929
PDBeChem:NH4
PMID:11319011
PMID:11341317
PMID:12096804
PMID:14512268
PMID:14879753
PMID:16345391
PMID:16903292
PMID:17392693
PMID:18515490
PMID:19199063
PMID:19596600
PMID:19682559
PMID:19716251
PMID:21993530
PMID:22265469
PMID:22524020
PMID:22562341
PMID:22631217
Reaxys:16093784
Wikipedia:Ammonium
ammonium
azanium
chebi_ontology
Ammonium(1+)
NH4(+)
NH4+
[NH4](+)
ammonium ion
ammonium
CAS:14798-03-9
ChemIDplus
CAS:14798-03-9
NIST Chemistry WebBook
Gmelin:84
Gmelin
PMID:11319011
Europe PMC
PMID:11341317
Europe PMC
PMID:12096804
Europe PMC
PMID:14512268
Europe PMC
PMID:14879753
Europe PMC
PMID:16345391
Europe PMC
PMID:16903292
Europe PMC
PMID:17392693
Europe PMC
PMID:18515490
Europe PMC
PMID:19199063
Europe PMC
PMID:19596600
Europe PMC
PMID:19682559
Europe PMC
PMID:19716251
Europe PMC
PMID:21993530
Europe PMC
PMID:22265469
Europe PMC
PMID:22524020
Europe PMC
PMID:22562341
Europe PMC
PMID:22631217
Europe PMC
Reaxys:16093784
Reaxys
ammonium
ChEBI
ammonium
IUPAC
azanium
IUPAC
Ammonium(1+)
ChemIDplus
NH4(+)
IUPAC
NH4(+)
UniProt
NH4+
KEGG_COMPOUND
[NH4](+)
MolBase
ammonium ion
PDBeChem
An ion of copper carrying a double positive charge.
+2
Cu
InChI=1S/Cu/q+2
JPVYNHNXODAKFH-UHFFFAOYSA-N
63.54600
62.92850
[Cu++]
CHEBI:20882
CHEBI:23380
CHEBI:49550
CAS:15158-11-9
Gmelin:6855
PDBeChem:CU
PMID:23900424
PMID:24168430
Reaxys:3587177
copper(2+)
copper(2+) ion
copper(II) cation
chebi_ontology
COPPER (II) ION
Cu(2+)
Cu(II)
Cu2+
copper(II) cation
copper, ion (Cu2+)
cupric ion
copper(2+)
CAS:15158-11-9
ChemIDplus
Gmelin:6855
Gmelin
PMID:23900424
Europe PMC
PMID:24168430
Europe PMC
Reaxys:3587177
Reaxys
copper(2+)
IUPAC
copper(2+) ion
IUPAC
copper(II) cation
IUPAC
COPPER (II) ION
PDBeChem
Cu(2+)
UniProt
Cu(II)
ChEBI
Cu2+
ChEBI
copper(II) cation
ChEBI
copper, ion (Cu2+)
ChemIDplus
cupric ion
ChEBI
+3
Cu
InChI=1S/Cu/q+3
XYNZKHQSHVOGHB-UHFFFAOYSA-N
63.544
62.92795
[Cu+3]
CHEBI:20883
CHEBI:23381
PDBeChem:CU3
Cu(3+)
copper(3+)
copper(3+) ion
copper(III) cation
chebi_ontology
Cu(III)
Cu3+
copper(III) cation
copper(3+)
Cu(3+)
IUPAC
copper(3+)
IUPAC
copper(3+) ion
IUPAC
copper(III) cation
IUPAC
Cu(III)
ChEBI
Cu3+
ChEBI
copper(III) cation
ChEBI
The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.
-1
CO2R
44.00950
43.98983
[O-]C([*])=O
CHEBI:13626
CHEBI:13945
CHEBI:23026
CHEBI:58657
chebi_ontology
a carboxylate
carboxylic acid anions
carboxylic anions
carboxylic acid anion
a carboxylate
UniProt
carboxylic acid anions
ChEBI
carboxylic anions
ChEBI
0
H2O3S
InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)
BDHFUVZGWQCTTF-UHFFFAOYSA-N
82.08008
81.97247
[H]S(O)(=O)=O
Gmelin:1404640
hydridohydroxidodioxidosulfur
sulfonic acid
chebi_ontology
HSHO3
Sulfonsaeure
[SHO2(OH)]
acide sulfonique
sulphonic acid
sulfonic acid
Gmelin:1404640
Gmelin
hydridohydroxidodioxidosulfur
IUPAC
sulfonic acid
IUPAC
HSHO3
IUPAC
Sulfonsaeure
ChEBI
[SHO2(OH)]
IUPAC
acide sulfonique
ChEBI
sulphonic acid
ChEBI
-1
H2N
InChI=1S/H2N/h1H2/q-1
HYGWNUKOUCZBND-UHFFFAOYSA-N
16.02262
16.01927
[H][N-][H]
amide
azanide
dihydridonitrate(1-)
chebi_ontology
NH2(-)
azanide
amide
IUPAC
azanide
IUPAC
dihydridonitrate(1-)
IUPAC
NH2(-)
IUPAC
A divalent inorganic anion resulting from the removal of two protons from ammonia.
-2
HN
InChI=1S/HN/h1H/q-2
DZQYTNGKSBCIOE-UHFFFAOYSA-N
15.01468
15.01200
[N--][H]
azanediide
hydridonitrate(2-)
chebi_ontology
NH(2-)
imide
hydridonitrate(2-)
azanediide
IUPAC
hydridonitrate(2-)
IUPAC
NH(2-)
IUPAC
imide
IUPAC
A carboxamide derived from a monocarboxylic acid.
0
CNOR3
42.01680
41.99799
[*]N([*])C([*])=O
CHEBI:13211
CHEBI:22207
CHEBI:25383
CHEBI:6977
chebi_ontology
monocarboxylic acid amides
monocarboxylic acid amide
monocarboxylic acid amides
ChEBI
0
HO3S
81.07214
80.96464
S(=O)(O)(*)=O
PDBeChem:SFO
SULFO GROUP
hydroxydioxo-lambda(6)-sulfanyl
hydroxysulfonyl
sulfo
chebi_ontology
-S(O)2(OH)
sulfo group
SULFO GROUP
PDBeChem
hydroxydioxo-lambda(6)-sulfanyl
IUPAC
hydroxysulfonyl
IUPAC
sulfo
IUPAC
-S(O)2(OH)
IUPAC
0
Cu
InChI=1S/Cu
RYGMFSIKBFXOCR-UHFFFAOYSA-N
63.54600
62.92960
[Cu]
CAS:7440-50-8
copper
copper(0)
chebi_ontology
Cu(0)
Cun
copper(0)
CAS:7440-50-8
ChemIDplus
CAS:7440-50-8
NIST Chemistry WebBook
copper
IUPAC
copper(0)
IUPAC
Cu(0)
ChEBI
Cun
IUPAC
Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force.
0
0.0
0.0
*
CHEBI:10581
CHEBI:14383
KEGG:C00205
photon
chebi_ontology
Lichtquant
Light
foton
gamma
hnu
light quantum
photon
photon
IUPAC
Lichtquant
ChEBI
Light
KEGG_COMPOUND
foton
ChEBI
gamma
IUPAC
hnu
IUPAC
hnu
UniProt
light quantum
ChEBI
+2
0.00000
[*++]
CHEBI:23856
CHEBI:4665
KEGG:C00572
chebi_ontology
Divalent cation
divalent inorganic cations
monoatomic dications
monoatomic dication
Divalent cation
KEGG_COMPOUND
divalent inorganic cations
ChEBI
monoatomic dications
ChEBI
A methanesulfonate (mesylate) salt that is the monomesylate salt of imatinib. Used for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours.
0
C29H31N7O.CH4O3S
C30H35N7O4S
InChI=1S/C29H31N7O.CH4O3S/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36;1-5(2,3)4/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34);1H3,(H,2,3,4)
YLMAHDNUQAMNNX-UHFFFAOYSA-N
589.70968
589.24712
CS(O)(=O)=O.CN1CCN(CC1)Cc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1
Beilstein:10229624
CAS:220127-57-1
DrugBank:DB00619
HMDB:HMDB0014757
KEGG:D01441
PMID:12047970
PMID:12616857
PMID:12669406
PMID:12975485
PMID:14760091
PMID:15059881
PMID:15161340
PMID:15206509
PMID:15250677
PMID:15601563
PMID:15727903
PMID:16570351
PMID:16805961
PMID:16835496
PMID:17212133
PMID:18422477
PMID:19073506
PMID:19258052
PMID:19508953
PMID:19542718
PMID:19568828
PMID:21084823
PMID:21333826
PMID:23462796
Patent:RU2365587
Patent:WO2004106326
Patent:WO2011161689
Patent:WO9903854
Reaxys:10229624
4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide methanesulfonate
chebi_ontology
Gleevec
Glivec
imatinib mesilate
imatinib mesylate
imatinib methansulfonate
imatinib monomesylate
imatinib methanesulfonate
Beilstein:10229624
Beilstein
CAS:220127-57-1
ChemIDplus
CAS:220127-57-1
KEGG DRUG
PMID:12047970
Europe PMC
PMID:12616857
Europe PMC
PMID:12669406
Europe PMC
PMID:12975485
Europe PMC
PMID:14760091
Europe PMC
PMID:15059881
Europe PMC
PMID:15161340
Europe PMC
PMID:15206509
Europe PMC
PMID:15250677
Europe PMC
PMID:15601563
Europe PMC
PMID:15727903
Europe PMC
PMID:16570351
Europe PMC
PMID:16805961
Europe PMC
PMID:16835496
Europe PMC
PMID:17212133
Europe PMC
PMID:18422477
Europe PMC
PMID:19073506
Europe PMC
PMID:19258052
Europe PMC
PMID:19508953
Europe PMC
PMID:19542718
Europe PMC
PMID:19568828
Europe PMC
PMID:21084823
Europe PMC
PMID:21333826
Europe PMC
PMID:23462796
Europe PMC
Reaxys:10229624
Reaxys
4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide methanesulfonate
IUPAC
Gleevec
DrugBank
Glivec
DrugBank
imatinib mesilate
DrugBank
imatinib mesylate
KEGG_DRUG
imatinib methansulfonate
DrugBank
imatinib monomesylate
ChEBI
An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
CHEBI:22473
CHEBI:2633
KEGG:C00241
Amide
amides
chebi_ontology
amide
Amide
KEGG_COMPOUND
amides
IUPAC
Intended use of the molecular entity or part thereof by humans.
chebi_ontology
application
A particle not known to have substructure.
elementary particle
chebi_ontology
elementary particles
fundamental particle
elementary particle
IUPAC
elementary particles
ChEBI
A monoatomic entity is a molecular entity consisting of a single atom.
chebi_ontology
atomic entity
monoatomic entities
monoatomic entity
atomic entity
ChEBI
monoatomic entities
ChEBI
chebi_ontology
oxoacid derivatives
oxoacid derivative
oxoacid derivatives
ChEBI
chebi_ontology
inorganic hydrides
inorganic hydride
inorganic hydrides
ChEBI
An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system.
chebi_ontology
organic fundamental parents
organic parent hydrides
organic fundamental parent
organic fundamental parents
ChEBI
organic parent hydrides
ChEBI
Any substituent group which does not contain carbon.
chebi_ontology
inorganic groups
inorganic group
inorganic groups
ChEBI
Any substituent group or skeleton containing carbon.
chebi_ontology
organic groups
organic group
organic groups
ChEBI
A univalent group formed by removing a hydrogen atom from a hydrocarbon.
hydrocarbyl group
hydrocarbyl groups
chebi_ontology
groupe hydrocarbyle
grupo hidrocarbilo
grupos hidrocarbilo
hydrocarbyl group
hydrocarbyl group
IUPAC
hydrocarbyl groups
IUPAC
groupe hydrocarbyle
IUPAC
grupo hidrocarbilo
IUPAC
grupos hidrocarbilo
IUPAC
Any organic substituent group, regardless of functional type, having one free valence at a carbon atom.
organyl group
organyl groups
chebi_ontology
groupe organyle
grupo organilo
grupos organilo
organyl group
organyl group
IUPAC
organyl groups
IUPAC
groupe organyle
IUPAC
grupo organilo
IUPAC
grupos organilo
IUPAC
Heavy nuclear particle: proton or neutron.
nucleon
chebi_ontology
Nukleon
Nukleonen
nucleons
nucleon
nucleon
IUPAC
nucleon
IUPAC
Nukleon
ChEBI
Nukleonen
ChEBI
nucleons
ChEBI
A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
primary amide
primary amides
chebi_ontology
primary amide
primary amide
IUPAC
primary amides
IUPAC
A molecular entity all atoms of which have the same atomic number.
chebi_ontology
homoatomic entity
homoatomic molecular entities
homoatomic molecular entity
elemental molecular entity
homoatomic entity
ChEBI
homoatomic molecular entities
ChEBI
homoatomic molecular entity
ChEBI
An organosulfur compound is a compound containing at least one carbon-sulfur bond.
CHEBI:23010
CHEBI:25714
Wikipedia:Organosulfur_compounds
organosulfur compound
chebi_ontology
organosulfur compounds
organosulfur compound
organosulfur compound
ChEBI
organosulfur compounds
ChEBI
An anion consisting of more than one atom.
chebi_ontology
polyatomic anions
polyatomic anion
polyatomic anions
ChEBI
A nutrient is a food component that an organism uses to survive and grow.
chebi_ontology
nutrients
nutrient
nutrients
ChEBI
A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.
chebi_ontology
heteroorganic entities
organoelement compounds
heteroorganic entity
heteroorganic entities
ChEBI
organoelement compounds
ChEBI
Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth.
pnictogens
chebi_ontology
group 15 elements
group V elements
nitrogenoideos
nitrogenoides
pnictogene
pnictogenes
pnictogen
pnictogens
IUPAC
group 15 elements
ChEBI
group V elements
ChEBI
nitrogenoideos
ChEBI
nitrogenoides
ChEBI
pnictogene
ChEBI
pnictogenes
ChEBI
A p-block molecular entity containing any pnictogen.
pnictogen molecular entity
chebi_ontology
pnictogen molecular entities
pnictogen molecular entity
pnictogen molecular entity
ChEBI
pnictogen molecular entities
ChEBI
Any p-block element belonging to the group 16 family of the periodic table.
PMID:17084588
chalcogen
chalcogens
chebi_ontology
Chalkogen
Chalkogene
anfigeno
anfigenos
calcogeno
calcogenos
chalcogene
chalcogenes
group 16 elements
group VI elements
chalcogen
PMID:17084588
Europe PMC
chalcogen
IUPAC
chalcogens
IUPAC
Chalkogen
ChEBI
Chalkogene
ChEBI
anfigeno
ChEBI
anfigenos
ChEBI
calcogeno
ChEBI
calcogenos
ChEBI
chalcogene
ChEBI
chalcogenes
ChEBI
group 16 elements
ChEBI
group VI elements
ChEBI
Any p-block molecular entity containing a chalcogen.
chalcogen molecular entity
chebi_ontology
chalcogen compounds
chalcogen molecular entities
chalcogen molecular entity
chalcogen molecular entity
ChEBI
chalcogen compounds
ChEBI
chalcogen molecular entities
ChEBI
group 14 elements
chebi_ontology
carbon group element
carbon group elements
carbonoides
cristallogene
cristallogenes
group IV elements
carbon group element atom
group 14 elements
IUPAC
carbon group element
ChEBI
carbon group elements
ChEBI
carbonoides
ChEBI
cristallogene
ChEBI
cristallogenes
ChEBI
group IV elements
ChEBI
An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table.
main group elements
chebi_ontology
Hauptgruppenelement
Hauptgruppenelemente
main group element
main group element atom
main group elements
IUPAC
Hauptgruppenelement
ChEBI
Hauptgruppenelemente
ChEBI
main group element
ChEBI
group 11 elements
chebi_ontology
coinage metals
copper group element
copper group elements
copper group element atom
group 11 elements
IUPAC
coinage metals
ChEBI
copper group element
ChEBI
copper group elements
ChEBI
chebi_ontology
oxoacids of sulfur
sulfur oxoacids
sulfur oxoacid
oxoacids of sulfur
ChEBI
sulfur oxoacids
ChEBI
sulfur oxoacid derivative
chebi_ontology
sulfur oxoacid derivatives
sulfur oxoacid derivative
sulfur oxoacid derivative
ChEBI
sulfur oxoacid derivatives
ChEBI
sulfur oxoanion
chebi_ontology
oxoanions of sulfur
sulfur oxoanions
sulfur oxoanion
sulfur oxoanion
ChEBI
oxoanions of sulfur
ChEBI
sulfur oxoanions
ChEBI
chalcogen oxoacid
chebi_ontology
chalcogen oxoacids
chalcogen oxoacid
chalcogen oxoacid
ChEBI
chalcogen oxoacids
ChEBI
chalcogen oxoanion
chebi_ontology
chalcogen oxoanions
chalcogen oxoanion
chalcogen oxoanion
ChEBI
chalcogen oxoanions
ChEBI
A molecular entity containing one or more atoms of a transition element.
chebi_ontology
transition element molecular entities
transition metal molecular entity
transition element molecular entity
transition element molecular entities
ChEBI
transition metal molecular entity
ChEBI
chebi_ontology
transition element cations
transition metal cation
transition element cation
transition element cations
ChEBI
transition metal cation
ChEBI
An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity.
CHEBI:25217
CHEBI:6788
KEGG:C00050
PMID:21784043
Wikipedia:Metal
chebi_ontology
elemental metal
elemental metals
metal element
metal elements
metals
metal atom
PMID:21784043
Europe PMC
elemental metal
ChEBI
elemental metals
ChEBI
metal element
ChEBI
metal elements
ChEBI
metals
ChEBI
The sulfur oxoanion formed by deprotonation of sulfonic acid.
-1
HO3S
InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)/p-1
BDHFUVZGWQCTTF-UHFFFAOYSA-M
81.07214
80.96519
[H]S([O-])(=O)=O
Gmelin:971569
hydridotrioxidosulfate(1-)
chebi_ontology
SHO3(-)
[SHO3](-)
sulfonates
sulfonate
Gmelin:971569
Gmelin
hydridotrioxidosulfate(1-)
IUPAC
SHO3(-)
IUPAC
[SHO3](-)
IUPAC
sulfonates
ChEBI
An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon.
0
HO3SR
81.07100
80.96464
OS([*])(=O)=O
chebi_ontology
organosulfonic acids
sulfonic acids
organosulfonic acid
organosulfonic acids
ChEBI
sulfonic acids
ChEBI
sulfonic acid derivative
chebi_ontology
derivatives of sulfonic acid
sulfonic acid derivatives
sulfonic acid derivative
sulfonic acid derivative
ChEBI
derivatives of sulfonic acid
ChEBI
sulfonic acid derivatives
ChEBI
An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid.
-1
O3SR
80.064
79.95681
*S([O-])(=O)=O
chebi_ontology
organosulfonate
organosulfonate oxoanions
organosulfonates
organosulfonate oxoanion
organosulfonate
ChEBI
organosulfonate oxoanions
ChEBI
organosulfonates
ChEBI
chebi_ontology
s-block element
s-block elements
s-block element atom
s-block element
ChEBI
s-block elements
ChEBI
Any main group element atom belonging to the p-block of the periodic table.
chebi_ontology
p-block element
p-block elements
p-block element atom
p-block element
ChEBI
p-block elements
ChEBI
chebi_ontology
d-block element
d-block elements
d-block element atom
d-block element
ChEBI
d-block elements
ChEBI
A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
0
CHO2R
45.01740
44.99765
OC([*])=O
CHEBI:13428
CHEBI:13627
CHEBI:23027
PMID:17147560
PMID:18433345
Wikipedia:Carboxylic_acid
carboxylic acid
carboxylic acids
chebi_ontology
Carbonsaeure
Carbonsaeuren
Karbonsaeure
RC(=O)OH
acide carboxylique
acides carboxyliques
acido carboxilico
acidos carboxilicos
carboxylic acid
PMID:17147560
Europe PMC
PMID:18433345
Europe PMC
carboxylic acid
IUPAC
carboxylic acids
IUPAC
Carbonsaeure
ChEBI
Carbonsaeuren
ChEBI
Karbonsaeure
ChEBI
RC(=O)OH
IUPAC
acide carboxylique
IUPAC
acides carboxyliques
IUPAC
acido carboxilico
IUPAC
acidos carboxilicos
IUPAC
A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table.
chebi_ontology
main group compounds
main group molecular entities
main group molecular entity
main group compounds
ChEBI
main group molecular entities
ChEBI
carbon group molecular entity
chebi_ontology
carbon group molecular entities
carbon group molecular entity
carbon group molecular entity
ChEBI
carbon group molecular entities
ChEBI
Any molecule that consists of a series of atoms joined together to form a ring.
Wikipedia:Cyclic_compound
chebi_ontology
cyclic compounds
cyclic compound
cyclic compounds
ChEBI
A cyclic compound having as ring members atoms of the same element only.
homocyclic compound
homocyclic compounds
chebi_ontology
isocyclic compounds
homocyclic compound
homocyclic compound
IUPAC
homocyclic compounds
IUPAC
isocyclic compounds
IUPAC
A homocyclic compound in which all of the ring members are carbon atoms.
carbocyclic compound
carbocyclic compounds
chebi_ontology
carbocycle
carbocyclic compound
carbocyclic compound
IUPAC
carbocyclic compounds
IUPAC
carbocycle
ChEBI
chebi_ontology
hydrogen compounds
hydrogen molecular entities
hydrogen molecular entity
hydrogen compounds
ChEBI
hydrogen molecular entities
ChEBI
Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds.
aliphatic compounds
chebi_ontology
aliphatic compound
aliphatic compounds
IUPAC
A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character.
aromatic compounds
aromatic molecular entity
chebi_ontology
aromatics
aromatische Verbindungen
aromatic compound
aromatic compounds
IUPAC
aromatic molecular entity
IUPAC
aromatics
ChEBI
aromatische Verbindungen
ChEBI
Any monocyclic or polycyclic aromatic hydrocarbon.
arene
arenes
chebi_ontology
aromatic hydrocarbons
arene
arene
IUPAC
arenes
IUPAC
aromatic hydrocarbons
IUPAC
chebi_ontology
organic aromatic compounds
organic aromatic compound
organic aromatic compounds
ChEBI
chebi_ontology
monocyclic compounds
monocyclic compound
monocyclic compounds
ChEBI
A mancude monocyclic hydrocarbon without side chains of the general formula CnHn (n is an even number) or CnHn+1 (n is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [n]annulene, where n is the number of carbon atoms.
annulene
annulenes
chebi_ontology
annulene
annulene
IUPAC
annulenes
IUPAC
cyclic hydrocarbon
chebi_ontology
cyclic hydrocarbons
cyclic hydrocarbon
cyclic hydrocarbon
ChEBI
cyclic hydrocarbons
ChEBI
monocyclic hydrocarbon
monocyclic hydrocarbons
chebi_ontology
monocyclic hydrocarbons
monocyclic hydrocarbon
monocyclic hydrocarbon
ChEBI
monocyclic hydrocarbons
IUPAC
monocyclic hydrocarbons
ChEBI
heteromonocyclic compound
heteromonocyclic compounds
chebi_ontology
heteromonocyclic compound
heteromonocyclic compound
IUPAC
heteromonocyclic compounds
IUPAC
An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element.
s-block molecular entity
chebi_ontology
s-block compounds
s-block molecular entities
s-block molecular entity
s-block molecular entity
ChEBI
s-block compounds
ChEBI
s-block molecular entities
ChEBI
A main group molecular entity that contains one or more atoms of a p-block element.
chebi_ontology
p-block compounds
p-block molecular entities
p-block molecular entitiy
p-block molecular entity
p-block compounds
ChEBI
p-block molecular entities
ChEBI
p-block molecular entitiy
ChEBI
A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element.
d-block molecular entity
chebi_ontology
d-block compounds
d-block molecular entities
d-block molecular entity
d-block molecular entity
ChEBI
d-block compounds
ChEBI
d-block molecular entities
ChEBI
Hydrides are chemical compounds of hydrogen with other chemical elements.
chebi_ontology
hydrides
When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue.
amino-acid residue
chebi_ontology
amino acid residue
amino-acid residues
amino-acid residue
amino-acid residue
IUPAC
amino acid residue
ChEBI
amino-acid residues
JCBN
A carboxylic acid containing one or more amino groups.
CHEBI:13815
CHEBI:22477
Wikipedia:Amino_acid
chebi_ontology
Aminocarbonsaeure
Aminokarbonsaeure
Aminosaeure
amino acids
amino acid
Aminocarbonsaeure
ChEBI
Aminokarbonsaeure
ChEBI
Aminosaeure
ChEBI
amino acids
ChEBI
copper group molecular entity
chebi_ontology
copper group molecular entities
copper group molecular entity
copper group molecular entity
ChEBI
copper group molecular entities
ChEBI
Any organic molecule that consists of atoms connected in the form of a ring.
chebi_ontology
organic cyclic compounds
organic cyclic compound
organic cyclic compounds
ChEBI
chebi_ontology
benzenoid aromatic compounds
benzenoid compound
benzenoid aromatic compound
benzenoid aromatic compounds
ChEBI
benzenoid compound
ChEBI
chebi_ontology
aromatic annulenes
aromatic annulene
aromatic annulenes
ChEBI
A monocyclic aromatic hydrocarbon.
chebi_ontology
monocyclic arenes
monocyclic arene
monocyclic arenes
ChEBI
An amino compound in which the amino group is linked directly to an aromatic system.
CHEBI:13827
CHEBI:22622
CHEBI:22646
CHEBI:2834
CHEBI:2863
chebi_ontology
aromatic amines
aryl amine
aryl amines
arylamine
arylamines
aromatic amine
aromatic amines
ChEBI
aryl amine
ChEBI
aryl amines
ChEBI
arylamine
ChEBI
arylamines
ChEBI
A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
reagent
chebi_ontology
reactif
reactivo
reagents
reagent
reagent
IUPAC
reactif
IUPAC
reactivo
IUPAC
reagents
ChEBI
chebi_ontology
macronutrient
chebi_ontology
nitrogen hydrides
nitrogen hydride
nitrogen hydrides
ChEBI
Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
chebi_ontology
azanes
azane
azanes
ChEBI
A substance that diminishes the rate of a chemical reaction.
inhibitor
chebi_ontology
inhibidor
inhibiteur
inhibitors
inhibitor
inhibitor
IUPAC
inhibidor
ChEBI
inhibiteur
ChEBI
inhibitors
ChEBI
Any heteroorganic entity containing at least one carbon-nitrogen bond.
organonitrogen compounds
chebi_ontology
organonitrogens
organonitrogen compound
organonitrogen compounds
IUPAC
organonitrogens
ChEBI
An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen.
CHEBI:33274
CHEBI:33436
oxoanion
chebi_ontology
oxoacid anions
oxoanions
oxoanion
oxoanion
ChEBI
oxoacid anions
ChEBI
oxoanions
ChEBI
chebi_ontology
carbon oxoacids
oxoacids of carbon
carbon oxoacid
carbon oxoacids
ChEBI
oxoacids of carbon
ChEBI
A substance that inhibits or prevents the proliferation of neoplasms.
chebi_ontology
anticancer agent
anticancer agents
antineoplastic
antineoplastic agents
cytostatic
antineoplastic agent
anticancer agent
ChEBI
anticancer agents
ChEBI
antineoplastic
ChEBI
antineoplastic agents
ChEBI
cytostatic
ChEBI
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
CHEBI:10074
CHEBI:27333
KEGG:C06708
Wikipedia:Xenobiotic
Xenobiotic
xenobiotic
xenobiotics
chebi_ontology
xenobiotic compounds
xenobiotic
Xenobiotic
KEGG_COMPOUND
xenobiotic
IUPAC
xenobiotics
IUPAC
xenobiotic compounds
ChEBI
pnictogen hydride
chebi_ontology
pnictogen hydrides
pnictogen hydride
pnictogen hydride
ChEBI
pnictogen hydrides
ChEBI
Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin).
chebi_ontology
leptons
lepton
leptons
ChEBI
Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy).
chebi_ontology
baryons
baryon
baryons
ChEBI
Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi.
fermion
chebi_ontology
fermions
fermion
fermion
IUPAC
fermions
ChEBI
Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose.
boson
chebi_ontology
bosons
boson
boson
IUPAC
bosons
ChEBI
A subatomic particle known to have substructure (i.e. consisting of smaller particles).
chebi_ontology
composite particles
composite particle
composite particles
ChEBI
Hadron is a subatomic particle which experiences the strong force.
chebi_ontology
hadrons
hadron
hadrons
ChEBI
A nucleus or any of its constituents in any of their energy states.
nuclear particle
chebi_ontology
nuclear particle
nuclear particle
IUPAC
Any molecular entity consisting of more than one atom.
chebi_ontology
polyatomic entities
polyatomic entity
polyatomic entities
ChEBI
An ion consisting of more than one atom.
chebi_ontology
polyatomic ions
polyatomic ion
polyatomic ions
ChEBI
Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives.
carbonyl compounds
chebi_ontology
carbonyl compound
carbonyl compounds
IUPAC
Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element.
oxo compounds
chebi_ontology
organic oxo compounds
organic oxo compound
oxo compounds
IUPAC
organic oxo compounds
ChEBI
chebi_ontology
inorganic ions
inorganic ion
inorganic ions
ChEBI
chebi_ontology
inorganic cations
inorganic cation
inorganic cations
ChEBI
A monoatomic or polyatomic species having one or more elementary charges of the proton.
CHEBI:23058
CHEBI:3473
KEGG:C01373
Cation
cation
chebi_ontology
Kation
Kationen
cationes
cations
cation
Cation
KEGG_COMPOUND
cation
ChEBI
cation
IUPAC
Kation
ChEBI
Kationen
ChEBI
cationes
ChEBI
cations
ChEBI
An organochalcogen compound is a compound containing at least one carbon-chalcogen bond.
organochalcogen compound
chebi_ontology
organochalcogen compounds
organochalcogen compound
organochalcogen compound
ChEBI
organochalcogen compounds
ChEBI
An organochalcogen compound containing at least one carbon-oxygen bond.
PMID:17586126
organooxygen compound
chebi_ontology
organooxygen compounds
organooxygen compound
PMID:17586126
Europe PMC
organooxygen compound
ChEBI
organooxygen compounds
ChEBI
amino-acid anion
chebi_ontology
amino acid anions
amino-acid anions
amino-acid anion
amino-acid anion
ChEBI
amino acid anions
ChEBI
amino-acid anions
ChEBI
chebi_ontology
organic hydrides
organic hydride
organic hydrides
ChEBI
mononuclear parent hydrides
chebi_ontology
mononuclear hydride
mononuclear hydrides
mononuclear parent hydride
mononuclear parent hydrides
IUPAC
mononuclear hydride
ChEBI
mononuclear hydrides
IUPAC
chebi_ontology
elemental copper
An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid).
CHEBI:13800
CHEBI:13801
CHEBI:22209
CHEBI:2426
KEGG:C00174
Acid
acid
chebi_ontology
Saeure
Saeuren
acide
acido
acids
acid
Acid
KEGG_COMPOUND
acid
IUPAC
Saeure
ChEBI
Saeuren
ChEBI
acide
IUPAC
acido
ChEBI
acids
ChEBI
A molecular entity consisting of two or more chemical elements.
chebi_ontology
chemical compound
heteroatomic molecular entities
heteroatomic molecular entity
chemical compound
ChEBI
heteroatomic molecular entities
ChEBI
An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom.
0
CNOR3
42.01680
41.99799
[*]C(=O)N([*])[*]
CHEBI:35354
CHEBI:35355
carboxamides
chebi_ontology
carboxamides
primary carboxamide
carboxamide
carboxamides
IUPAC
carboxamides
ChEBI
primary carboxamide
ChEBI
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
chebi_ontology
protein kinase inhibitors
protein kinase inhibitor
protein kinase inhibitors
ChEBI
A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid.
carboacyl groups
carboxylic acyl group
chebi_ontology
carboxylic acyl groups
carboacyl group
carboacyl groups
IUPAC
carboxylic acyl group
IUPAC
carboxylic acyl groups
IUPAC
chebi_ontology
mesylate salt
mesylate salts
methanesulfonate salts
methanesulfonate salt
mesylate salt
ChEBI
mesylate salts
ChEBI
methanesulfonate salts
ChEBI
Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms.
chebi_ontology
heterocyclic organonitrogen compounds
organonitrogen heterocyclic compounds
organonitrogen heterocyclic compound
heterocyclic organonitrogen compounds
ChEBI
organonitrogen heterocyclic compounds
ChEBI
Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure).
chebi_ontology
diazines
Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
Wikipedia:Tyrosine-kinase_inhibitor
chebi_ontology
TKI inhibitor
TKI inhibitors
protein tyrosine kinase inhibitor
protein tyrosine kinase inhibitors
tyrosine kinase inhibitors
tyrphostin
tyrphostins
tyrosine kinase inhibitor
TKI inhibitor
ChEBI
TKI inhibitors
ChEBI
protein tyrosine kinase inhibitor
ChEBI
protein tyrosine kinase inhibitors
ChEBI
tyrosine kinase inhibitors
ChEBI
tyrphostin
ChEBI
tyrphostins
ChEBI
An analogue of imatinib where the piperidine N-methyl group is replaced by 2-aminoethyl.
0
C30H34N8O
InChI=1S/C30H34N8O/c1-22-4-9-26(19-28(22)36-30-33-13-10-27(35-30)25-3-2-12-32-20-25)34-29(39)24-7-5-23(6-8-24)21-38-17-15-37(14-11-31)16-18-38/h2-10,12-13,19-20H,11,14-18,21,31H2,1H3,(H,34,39)(H,33,35,36)
GYQHZALGPJRESJ-UHFFFAOYSA-N
522.64428
522.28556
Cc1ccc(NC(=O)c2ccc(CN3CCN(CCN)CC3)cc2)cc1Nc1nccc(n1)-c1cccnc1
4-{[4-(2-aminoethyl)piperazin-1-yl]methyl}-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide
chebi_ontology
linkable imatinib analogue
4-{[4-(2-aminoethyl)piperazin-1-yl]methyl}-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide
IUPAC
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
Bronsted acid
chebi_ontology
Bronsted-Saeure
acide de Bronsted
donneur d'hydron
hydron donor
Bronsted acid
Bronsted acid
IUPAC
Bronsted-Saeure
ChEBI
acide de Bronsted
IUPAC
donneur d'hydron
IUPAC
hydron donor
IUPAC
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
Bronsted base
chebi_ontology
Bronsted-Base
accepteur d'hydron
base de Bronsted
hydron acceptor
Bronsted base
Bronsted base
IUPAC
Bronsted-Base
ChEBI
accepteur d'hydron
IUPAC
base de Bronsted
IUPAC
hydron acceptor
IUPAC
A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct.
Lewis base
chebi_ontology
Lewis-Base
base de Lewis
donneur d'une paire d'electrons
electron donor
Lewis base
Lewis base
IUPAC
Lewis-Base
ChEBI
base de Lewis
IUPAC
donneur d'une paire d'electrons
ChEBI
electron donor
ChEBI
Any compound having a pyrimidine as part of its structure.
CHEBI:13681
CHEBI:26448
chebi_ontology
pyrimidines
0
HO
17.00734
17.00274
*O[H]
CHEBI:24706
CHEBI:43171
PDBeChem:OH
HYDROXY GROUP
hydroxy
hydroxy group
chebi_ontology
-OH
hydroxyl
hydroxyl group
hydroxy group
HYDROXY GROUP
PDBeChem
hydroxy
IUPAC
hydroxy group
UniProt
-OH
IUPAC
hydroxyl
ChEBI
hydroxyl group
ChEBI
A benzamide obtained by formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary aromatic amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine. Used (as its mesylate salt) for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours.
0
C29H31N7O
InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
KTUFNOKKBVMGRW-UHFFFAOYSA-N
493.60270
493.25901
CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1
CHEBI:305376
CHEBI:38918
CHEBI:45781
Beilstein:7671333
CAS:152459-95-5
DrugBank:DB00619
Drug_Central:1423
HMDB:HMDB0014757
KEGG:D08066
LINCS:LSM-1023
PDBeChem:STI
PMID:14660054
PMID:14715630
PMID:15073101
PMID:15170967
PMID:15722647
PMID:15794712
PMID:15966213
PMID:16122278
PMID:16826359
PMID:16983347
PMID:17190842
PMID:17410337
PMID:17457302
PMID:17717205
PMID:18193246
PMID:18216472
PMID:18337118
PMID:18344535
PMID:18376233
PMID:18407734
PMID:18420270
PMID:18423008
PMID:18548219
PMID:18623899
PMID:18780518
PMID:18809244
PMID:19020005
PMID:19052981
PMID:19077095
PMID:19097599
PMID:19182535
PMID:19242505
PMID:19415889
PMID:19527930
PMID:19591692
PMID:19693287
PMID:19749465
PMID:19810774
PMID:19853594
PMID:19920908
PMID:22891806
PMID:23075630
PMID:23183914
PMID:23313020
PMID:23394269
PMID:23480638
PMID:23503753
PMID:23536338
PMID:23574742
PMID:23580311
PMID:23587588
Patent:EP564409
Patent:US5521184
Reaxys:7671333
Wikipedia:Imatinib
4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide
chebi_ontology
4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
STI 571
alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide
imatinib
imatinib
PMID:17190842
Europe PMC
PMID:17410337
Europe PMC
PMID:17457302
Europe PMC
PMID:17717205
Europe PMC
PMID:18193246
Europe PMC
PMID:18216472
Europe PMC
PMID:18337118
Europe PMC
PMID:18344535
Europe PMC
PMID:18376233
Europe PMC
PMID:18407734
Europe PMC
PMID:18420270
Europe PMC
PMID:18423008
Europe PMC
PMID:18548219
Europe PMC
PMID:18623899
Europe PMC
PMID:18780518
Europe PMC
PMID:18809244
Europe PMC
PMID:19020005
Europe PMC
PMID:19052981
Europe PMC
PMID:19077095
Europe PMC
PMID:19097599
Europe PMC
PMID:19182535
Europe PMC
PMID:19242505
Europe PMC
PMID:19415889
Europe PMC
PMID:19527930
Europe PMC
PMID:19591692
Europe PMC
PMID:19693287
Europe PMC
PMID:19749465
Europe PMC
PMID:19810774
Europe PMC
PMID:19853594
Europe PMC
PMID:19920908
Europe PMC
PMID:22891806
Europe PMC
PMID:23075630
Europe PMC
PMID:23183914
Europe PMC
PMID:23313020
Europe PMC
PMID:23394269
Europe PMC
PMID:23480638
Europe PMC
PMID:23503753
Europe PMC
PMID:23536338
Europe PMC
PMID:23574742
Europe PMC
PMID:23580311
Europe PMC
PMID:23587588
Europe PMC
Reaxys:7671333
Reaxys
4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide
IUPAC
4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
PDBeChem
STI 571
ChemIDplus
alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide
ChemIDplus
imatinib
ChemIDplus
Beilstein:7671333
Beilstein
CAS:152459-95-5
ChemIDplus
Drug_Central:1423
DrugCentral
PMID:14660054
Europe PMC
PMID:14715630
Europe PMC
PMID:15073101
Europe PMC
PMID:15170967
Europe PMC
PMID:15722647
Europe PMC
PMID:15794712
Europe PMC
PMID:15966213
Europe PMC
PMID:16122278
Europe PMC
PMID:16826359
Europe PMC
PMID:16983347
Europe PMC
0
O
15.99940
15.99491
O=*
CHEBI:29353
CHEBI:44607
PDBeChem:O
OXO GROUP
oxo
chebi_ontology
=O
oxo group
OXO GROUP
PDBeChem
oxo
IUPAC
=O
IUPAC
A liquid that can dissolve other substances (solutes) without any change in their chemical composition.
Wikipedia:Solvent
chebi_ontology
Loesungsmittel
solvant
solvents
solvent
Loesungsmittel
ChEBI
solvant
ChEBI
solvents
ChEBI
chebi_ontology
N-alkylpiperazines
N-alkylpiperazine
N-alkylpiperazines
ChEBI
0
CHO2
45.01744
44.99765
*C(=O)O
CHEBI:23025
CHEBI:41420
PDBeChem:FMT
CARBOXY GROUP
carboxy
chebi_ontology
-C(O)OH
-CO2H
-COOH
carboxyl group
carboxy group
CARBOXY GROUP
PDBeChem
carboxy
IUPAC
-C(O)OH
IUPAC
-CO2H
ChEBI
-COOH
IUPAC
carboxyl group
ChEBI
chebi_ontology
N-methylpiperazines
N-methylpiperazine
N-methylpiperazines
ChEBI
Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an alkyl group.
CHEBI:13809
CHEBI:33553
chebi_ontology
alkanesulfonic acids
alkylsulfonic acids
alkanesulfonic acid
alkanesulfonic acids
ChEBI
alkylsulfonic acids
ChEBI
chebi_ontology
Schwefeloxide
oxides of sulfur
sulfur oxides
sulfur oxide
Schwefeloxide
ChEBI
oxides of sulfur
ChEBI
sulfur oxides
ChEBI
chebi_ontology
non-polar solvent
Esters or salts of methanesulfonic acid.
chebi_ontology
methanesulfonates
0
H2O3S
InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)
LSNNMFCWUKXFEE-UHFFFAOYSA-N
82.08008
81.97247
OS(O)=O
CHEBI:26837
CHEBI:9344
CAS:7782-99-2
Gmelin:1458
KEGG:C00094
KNApSAcK:C00019662
PDBeChem:SO3
UM-BBD_compID:c0348
Sulfurous acid
dihydrogen trioxosulfate
dihydroxidooxidosulfur
sulfurous acid
trioxosulfuric acid
chebi_ontology
H2SO3
S(O)(OH)2
Sulfite
[SO(OH)2]
acide sulfureux
acido sulfuroso
schweflige Saeure
sulphurous acid
sulfurous acid
CAS:7782-99-2
ChemIDplus
Gmelin:1458
Gmelin
UM-BBD_compID:c0348
UM-BBD
Sulfurous acid
KEGG_COMPOUND
dihydrogen trioxosulfate
IUPAC
dihydroxidooxidosulfur
IUPAC
sulfurous acid
IUPAC
trioxosulfuric acid
IUPAC
H2SO3
IUPAC
S(O)(OH)2
IUPAC
Sulfite
KEGG_COMPOUND
[SO(OH)2]
IUPAC
acide sulfureux
ChEBI
acido sulfuroso
ChEBI
schweflige Saeure
ChemIDplus
sulphurous acid
ChemIDplus
+1
Cu
InChI=1S/Cu/q+1
VMQMZMRVKUZKQL-UHFFFAOYSA-N
63.54600
62.92905
[Cu+]
CHEBI:23379
CHEBI:49551
CAS:17493-86-6
Gmelin:15189
PDBeChem:CU1
copper(1+)
copper(1+) ion
copper(I) cation
chebi_ontology
COPPER (I) ION
Cu(+)
copper cation
copper(1+) ion
copper(I) cation
cuprous ion
copper(1+)
CAS:17493-86-6
ChemIDplus
CAS:17493-86-6
NIST Chemistry WebBook
Gmelin:15189
Gmelin
copper(1+)
IUPAC
copper(1+) ion
IUPAC
copper(I) cation
IUPAC
COPPER (I) ION
PDBeChem
Cu(+)
IUPAC
Cu(+)
UniProt
copper cation
NIST_Chemistry_WebBook
copper(1+) ion
ChEBI
copper(I) cation
ChEBI
cuprous ion
ChemIDplus
0
H
InChI=1S/H
YZCKVEUIGOORGS-UHFFFAOYSA-N
1.00794
1.00783
[H]
CHEBI:24634
CHEBI:49636
WebElements:H
hydrogen
chebi_ontology
1H
H
Wasserstoff
hidrogeno
hydrogen
hydrogene
hydrogen atom
hydrogen
IUPAC
1H
IUPAC
H
IUPAC
Wasserstoff
ChEBI
hidrogeno
ChEBI
hydrogen
ChEBI
hydrogene
ChEBI
A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups.
chebi_ontology
organic amino compounds
organic amino compound
organic amino compounds
ChEBI
chebi_ontology
onium compound
Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families.
onium cations
chebi_ontology
onium cations
onium ion
onium ions
onium cation
onium cations
IUPAC
onium cations
ChEBI
onium ion
ChEBI
onium ions
ChEBI
Any molecular entity that contains carbon.
CHEBI:25700
CHEBI:33244
chebi_ontology
organic compounds
organic entity
organic molecular entities
organic molecular entity
organic compounds
ChEBI
organic entity
ChEBI
organic molecular entities
ChEBI
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
chebi_ontology
agente carcinogeno
cancerigene
cancerogene
carcinogen
carcinogene
carcinogenic agents
carcinogeno
carcinogens
carcinogenic agent
agente carcinogeno
ChEBI
cancerigene
ChEBI
cancerogene
ChEBI
carcinogen
ChEBI
carcinogene
ChEBI
carcinogenic agents
ChEBI
carcinogeno
ChEBI
carcinogens
ChEBI
A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
Wikipedia:Allergen
chebi_ontology
alergeno
allergene
allergenic agent
allergen
alergeno
ChEBI
allergene
ChEBI
allergenic agent
ChEBI
A role is particular behaviour which a material entity may exhibit.
chebi_ontology
role
A poison that interferes with the functions of the nervous system.
CHEBI:50911
Wikipedia:Neurotoxin
chebi_ontology
agente neurotoxico
nerve poison
nerve poisons
neurotoxic agent
neurotoxic agents
neurotoxicant
neurotoxins
neurotoxin
agente neurotoxico
ChEBI
nerve poison
ChEBI
nerve poisons
ChEBI
neurotoxic agent
ChEBI
neurotoxic agents
ChEBI
neurotoxicant
ChEBI
neurotoxins
ChEBI
A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups.
chebi_ontology
tertiary amino compounds
tertiary amino compound
tertiary amino compounds
ChEBI
A role played by the molecular entity or part thereof within a chemical context.
chebi_ontology
chemical role
CHEBI:25556
CHEBI:7594
KEGG:C06061
chebi_ontology
Nitrogenous compounds
nitrogen compounds
nitrogen molecular entities
nitrogen molecular entity
Nitrogenous compounds
KEGG_COMPOUND
nitrogen compounds
ChEBI
nitrogen molecular entities
ChEBI
Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s).
chebi_ontology
organodiyl groups
organodiyl group
organodiyl groups
ChEBI
chebi_ontology
organic divalent group
chebi_ontology
organic univalent group
A biological role played by the molecular entity or part thereof within a biochemical context.
chebi_ontology
biochemical role
A role played by the molecular entity or part thereof which causes the development of a pathological process.
chebi_ontology
etiopathogenetic agent
etiopathogenetic role
aetiopathogenetic role
etiopathogenetic agent
ChEBI
etiopathogenetic role
ChEBI
chebi_ontology
physiological role
Any substance introduced into a living organism with therapeutic or diagnostic purpose.
CHEBI:33293
CHEBI:33294
chebi_ontology
farmaco
medicament
pharmaceuticals
pharmaceutical
farmaco
ChEBI
medicament
ChEBI
pharmaceuticals
ChEBI
A cyclic compound having as ring members atoms of at least two different elements.
Heterocyclic compound
chebi_ontology
compuesto heterociclico
compuestos heterociclicos
heterocycle
heterocyclic compounds
heterocyclic compound
Heterocyclic compound
KEGG_COMPOUND
compuesto heterociclico
IUPAC
compuestos heterociclicos
IUPAC
heterocycle
ChEBI
heterocyclic compounds
ChEBI
A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons.
chebi_ontology
nucleophile
nucleophiles
nucleophilic reagents
nucleophilic reagent
nucleophile
ChEBI
nucleophiles
ChEBI
nucleophilic reagents
ChEBI
A metal cation with a valence of two.
chebi_ontology
a divalent metal cation
divalent metal cation
a divalent metal cation
UniProt
An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one.
chebi_ontology
a monovalent cation
monovalent inorganic cation
a monovalent cation
UniProt
An alkanesulfonate in which the carbon at position 1 is attached to at least two hydrogens.
-1
CH2O3SR
94.09000
93.97246
[H]C([H])([*])S([O-])(=O)=O
KEGG:C15521
MetaCyc:Alkanesulfonates
chebi_ontology
1,1-di-unsubstituted alkanesulfonate
1,1-di-unsubstituted alkanesulfonates
1,1-diunsubstituted alkanesulfonates
1,1-diunsubstituted alkanesulfonate
1,1-di-unsubstituted alkanesulfonate
ChEBI
1,1-di-unsubstituted alkanesulfonates
ChEBI
1,1-diunsubstituted alkanesulfonates
ChEBI
An amide in which the amide linkage is bonded directly to an aromatic system.
chebi_ontology
aromatic amides
aromatic amide
aromatic amides
ChEBI
Any organic salt prepared using an organosulfonic acid as the acid component.
chebi_ontology
organosulfonate salts
organosulphonate salt
organosulphonate salts
organosulfonate salt
organosulfonate salts
ChEBI
organosulphonate salt
ChEBI
organosulphonate salts
ChEBI
An inorganic cation with a valency of two.
chebi_ontology
divalent inorganic cation
An organic molecular entity containing a single carbon atom (C1).
chebi_ontology
one-carbon compounds
one-carbon compound
one-carbon compounds
ChEBI
Any organic molecular entity that is acidic and contains carbon in covalent linkage.
chebi_ontology
organic acids
organic acid
organic acids
ChEBI
An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of three.
chebi_ontology
trivalent inorganic cation
Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism.
Wikipedia:Poison
chebi_ontology
poisonous agent
poisonous agents
poisonous substance
poisonous substances
poisons
toxic agent
toxic agents
toxic substance
toxic substances
poison
poisonous agent
ChEBI
poisonous agents
ChEBI
poisonous substance
ChEBI
poisonous substances
ChEBI
poisons
ChEBI
toxic agent
ChEBI
toxic agents
ChEBI
toxic substance
ChEBI
toxic substances
ChEBI
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
chebi_ontology
Type I cell-death inducer
Type I cell-death inducers
Type I programmed cell-death inducer
Type I programmed cell-death inducers
apoptosis inducers
apoptosis inducer
Type I cell-death inducer
ChEBI
Type I cell-death inducers
ChEBI
Type I programmed cell-death inducer
ChEBI
Type I programmed cell-death inducers
ChEBI
apoptosis inducers
ChEBI
An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)
Wikipedia:Transferase
chebi_ontology
EC 2 inhibitor
EC 2 inhibitors
EC 2.* (transferase) inhibitors
EC 2.* inhibitor
EC 2.* inhibitors
transferase inhibitor
transferase inhibitors
EC 2.* (transferase) inhibitor
EC 2 inhibitor
ChEBI
EC 2 inhibitors
ChEBI
EC 2.* (transferase) inhibitors
ChEBI
EC 2.* inhibitor
ChEBI
EC 2.* inhibitors
ChEBI
transferase inhibitor
ChEBI
transferase inhibitors
ChEBI
Any molecule that consists of at least one carbon atom as part of the electrically neutral entity.
chebi_ontology
organic compound
organic compounds
organic molecules
organic molecule
organic compound
ChEBI
organic compounds
ChEBI
organic molecules
ChEBI
Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
chebi_ontology
eukaryotic metabolites
eukaryotic metabolite
eukaryotic metabolites
ChEBI
Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
CHEBI:77721
CHEBI:77743
chebi_ontology
animal metabolites
animal metabolite
animal metabolites
ChEBI
Any animal metabolite produced during a metabolic reaction in mammals.
CHEBI:77464
CHEBI:77744
chebi_ontology
mammalian metabolites
mammalian metabolite
mammalian metabolites
ChEBI
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
chebi_ontology
Mus musculus metabolite
Mus musculus metabolites
mouse metabolites
mouse metabolite
Mus musculus metabolite
ChEBI
Mus musculus metabolites
ChEBI
mouse metabolites
ChEBI
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).
CHEBI:76949
CHEBI:76951
chebi_ontology
S. cerevisiae metabolite
S. cerevisiae metabolites
S. cerevisiae secondary metabolite
S. cerevisiae secondary metabolites
Saccharomyces cerevisiae metabolites
Saccharomyces cerevisiae secondary metabolites
baker's yeast metabolite
baker's yeast metabolites
baker's yeast secondary metabolite
baker's yeast secondary metabolites
Saccharomyces cerevisiae metabolite
S. cerevisiae metabolite
ChEBI
S. cerevisiae metabolites
ChEBI
S. cerevisiae secondary metabolite
ChEBI
S. cerevisiae secondary metabolites
ChEBI
Saccharomyces cerevisiae metabolites
ChEBI
Saccharomyces cerevisiae secondary metabolites
ChEBI
baker's yeast metabolite
ChEBI
baker's yeast metabolites
ChEBI
baker's yeast secondary metabolite
ChEBI
baker's yeast secondary metabolites
ChEBI
Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.
chebi_ontology
prokaryotic metabolites
prokaryotic metabolite
prokaryotic metabolites
ChEBI
A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*).
chebi_ontology
EC 2.7.* (P-containing group transferase) inhibitors
EC 2.7.* (phosphorus-containing group transferase) inhibitor
EC 2.7.* (phosphorus-containing group transferase) inhibitors
EC 2.7.* inhibitor
EC 2.7.* inhibitors
phosphorus-containing group transferase (EC 2.7.*) inhibitor
phosphorus-containing group transferase (EC 2.7.*) inhibitors
phosphorus-containing group transferase inhibitor
phosphorus-containing group transferase inhibitors
EC 2.7.* (P-containing group transferase) inhibitor
EC 2.7.* (P-containing group transferase) inhibitors
ChEBI
EC 2.7.* (phosphorus-containing group transferase) inhibitor
ChEBI
EC 2.7.* (phosphorus-containing group transferase) inhibitors
ChEBI
EC 2.7.* inhibitor
ChEBI
EC 2.7.* inhibitors
ChEBI
phosphorus-containing group transferase (EC 2.7.*) inhibitor
ChEBI
phosphorus-containing group transferase (EC 2.7.*) inhibitors
ChEBI
phosphorus-containing group transferase inhibitor
ChEBI
phosphorus-containing group transferase inhibitors
ChEBI
Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*).
Wikipedia:Hydrolase
chebi_ontology
EC 3.* (hydrolase) inhibitors
EC 3.* inhibitor
EC 3.* inhibitors
EC 3.*.*.* inhibitor
EC 3.*.*.* inhibitors
hydrolase (EC 3.*) inhibitor
hydrolase (EC 3.*) inhibitors
hydrolase inhibitor
hydrolase inhibitors
EC 3.* (hydrolase) inhibitor
EC 3.* (hydrolase) inhibitors
ChEBI
EC 3.* inhibitor
ChEBI
EC 3.* inhibitors
ChEBI
EC 3.*.*.* inhibitor
ChEBI
EC 3.*.*.* inhibitors
ChEBI
hydrolase (EC 3.*) inhibitor
ChEBI
hydrolase (EC 3.*) inhibitors
ChEBI
hydrolase inhibitor
ChEBI
hydrolase inhibitors
ChEBI
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*).
chebi_ontology
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
EC 3.5.* inhibitor
EC 3.5.* inhibitors
EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
ChEBI
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
ChEBI
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
ChEBI
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
ChEBI
EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
ChEBI
EC 3.5.* inhibitor
ChEBI
EC 3.5.* inhibitors
ChEBI
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*).
chebi_ontology
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
EC 3.5.1.* inhibitor
EC 3.5.1.* inhibitors
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
ChEBI
EC 3.5.1.* inhibitor
ChEBI
EC 3.5.1.* inhibitors
ChEBI
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
ChEBI
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
ChEBI
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
CHEBI:75765
CHEBI:76947
chebi_ontology
fungal metabolites
fungal metabolite
fungal metabolites
ChEBI
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
CHEBI:75760
CHEBI:76970
chebi_ontology
bacterial metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
chebi_ontology
E.coli metabolite
E.coli metabolites
Escherichia coli metabolites
Escherichia coli metabolite
E.coli metabolite
ChEBI
E.coli metabolites
ChEBI
Escherichia coli metabolites
ChEBI
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
CHEBI:75770
CHEBI:77123
chebi_ontology
H. sapiens metabolite
H. sapiens metabolites
Homo sapiens metabolite
Homo sapiens metabolites
human metabolite
H. sapiens metabolite
ChEBI
H. sapiens metabolites
ChEBI
Homo sapiens metabolite
ChEBI
Homo sapiens metabolites
ChEBI
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4).
Wikipedia:Amidase
chebi_ontology
EC 3.5.1.4 (amidase) inhibitors
EC 3.5.1.4 inhibitor
EC 3.5.1.4 inhibitors
N-acetylaminohydrolase inhibitor
N-acetylaminohydrolase inhibitors
acylamidase inhibitor
acylamidase inhibitors
acylamide amidohydrolase inhibitor
acylamide amidohydrolase inhibitors
amidase (EC 3.5.1.4) inhibitor
amidase (EC 3.5.1.4) inhibitors
amidase inhibitor
amidase inhibitors
amidohydrolase inhibitor
amidohydrolase inhibitors
deaminase inhibitor
deaminase inhibitors
fatty acylamidase inhibitor
fatty acylamidase inhibitors
EC 3.5.1.4 (amidase) inhibitor
EC 3.5.1.4 (amidase) inhibitors
ChEBI
EC 3.5.1.4 inhibitor
ChEBI
EC 3.5.1.4 inhibitors
ChEBI
N-acetylaminohydrolase inhibitor
ChEBI
N-acetylaminohydrolase inhibitors
ChEBI
acylamidase inhibitor
ChEBI
acylamidase inhibitors
ChEBI
acylamide amidohydrolase inhibitor
ChEBI
acylamide amidohydrolase inhibitors
ChEBI
amidase (EC 3.5.1.4) inhibitor
ChEBI
amidase (EC 3.5.1.4) inhibitors
ChEBI
amidase inhibitor
ChEBI
amidase inhibitors
ChEBI
amidohydrolase inhibitor
ChEBI
amidohydrolase inhibitors
ChEBI
deaminase inhibitor
ChEBI
deaminase inhibitors
ChEBI
fatty acylamidase inhibitor
ChEBI
fatty acylamidase inhibitors
ChEBI
Any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
chebi_ontology
dietary component
dietary components
food components
food component
dietary component
ChEBI
dietary components
ChEBI
food components
ChEBI
Any minor or unwanted substance introduced into the environment that can have undesired effects.
chebi_ontology
environmental contaminants
environmental contaminant
environmental contaminants
ChEBI
A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
Wikipedia:Refrigerant
chebi_ontology
refrigerants
refrigerant
refrigerants
ChEBI
Any inorganic anion with a valency of two.
chebi_ontology
divalent inorganic anions
divalent inorganic anion
divalent inorganic anions
ChEBI
Any inorganic anion with a valency of one.
chebi_ontology
monovalent inorganic anions
monovalent inorganic anion
monovalent inorganic anions
ChEBI
Any metal which causes the onset of an allergic reaction.
chebi_ontology
allergenic metal
allergenic metals
metal allergens
metal allergen
allergenic metal
ChEBI
allergenic metals
ChEBI
metal allergens
ChEBI
A cell that will develop into a neuron often after a migration phase.
CL:0000337
BTO:0000930
FMA:70563
neuroblast
cell
neuroblast (sensu Vertebrata)
A cell that will develop into a neuron often after a migration phase.
GOC:NV
http://en.wikipedia.org/wiki/Neuroblast
A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
CALOHA:TS-2086
FMA:63368
cell
stem cell
A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
GOC:tfm
MESH:A11.872
A stem cell that self-renews as well as give rise to a single mature cell type.
FMA:70569
unipotent stem cell
unipotential stem cell
cell
single fate stem cell
A stem cell that self-renews as well as give rise to a single mature cell type.
GOC:tfm
A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.
BTO:0000725
CALOHA:TS-0448
FMA:70337
FMA:86475
VHOG:0001485
HSC
blood forming stem cell
hemopoietic stem cell
cell
colony forming unit hematopoietic
Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative.
hematopoietic stem cell
true
A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.
GOC:add
GOC:dsd
GOC:tfm
PMID:19022770
http://en.wikipedia.org/wiki/Hematopoietic_stem_cell
A stem cell that can give rise to multiple lineages of cells.
FMA:84789
multi-fate stem cell
multifate stem cell
multipotent cell
multipotent stem cell
cell
multi fate stem cell
A stem cell that can give rise to multiple lineages of cells.
GOC:add
A oligopotent progenitor cell committed to the lymphoid lineage.
CL:0000044
CLP
common lymphocyte precursor
common lymphocyte progenitor
common lymphoid precursor
cell
ELP
committed lymphopoietic stem cell
early lymphocyte progenitor
lymphoid stem cell
lymphopoietic stem cell
CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.
common lymphoid progenitor
true
A oligopotent progenitor cell committed to the lymphoid lineage.
GOC:add
GOC:dsd
GOC:tfm
PMID:10407577
PMID:16551251
A precursor cell with a limited number of potential fates.
BTO:0000125
FMA:84782
blast cell
cell
define using PATO mulit-potent or oligopotent?
non-terminally differentiated cell
A precursor cell with a limited number of potential fates.
SANBI:mhl
A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
CL:0000804
CL:0000812
BTO:0000782
CALOHA:TS-1001
FMA:62870
VHOG:0001479
T lymphocyte
T-cell
T-lymphocyte
cell
immature T cell
mature T cell
T cell
true
A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
GOC:add
GOC:tfm
ISBN:0781735149
Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.
BTO:0003811
FBbt:00005125
FMA:67313
WBbt:0005113
cell
interneuron
Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.
GOC:tfm
MESH:A08.663.358
A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.
CL:0002452
BTO:0002625
BTO:0003298
FMA:70546
BMSC
bone marrow stromal cells
colony-forming unit-fibroblast
marrow stromal cells
cell
CFU-F
MSC
mesenchymal precursor cell
mesenchymal progenitor cells
mesenchymal stem cell
mesenchymal stromal cell
mesenchymal stromal cells
stem cells, mesenchymal
Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2.
mesenchymal stem cell
true
A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.
FB:ma
GOC:dsd
PMCID:PMC2613570
PMID:10102814j
PMID:16923606
PMID:17986482
PMID:19960544
http://en.wikipedia.org/wiki/Mesenchymal_stem_cell
http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells
marrow stromal cells
PMID:11378515
MSC
PMID:11378515
mesenchymal progenitor cells
MESH:D044982
mesenchymal stromal cells
stem cells, mesenchymal
MESH:D044982
A cell whose function is determined by the generation or the reception of an electric signal.
cell
electrically active cell
A cell whose function is determined by the generation or the reception of an electric signal.
FB:ma
A cell with a single nucleus.
cell
single nucleate cell
A cell with a single nucleus.
FB:ma
GOC:tfm
cell
eukaryotic cell
A cell whose function is determined by its response to an electric signal.
cell
electrically responsive cell
A cell whose function is determined by its response to an electric signal.
FB:ma
A cell that initiates an electrical signal and passes that signal to another cell.
cell
electrically signaling cell
A cell that initiates an electrical signal and passes that signal to another cell.
FB:ma
The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
BTO:0000938
CALOHA:TS-0683
FBbt:00005106
FMA:54527
VHOG:0001483
WBbt:0003679
nerve cell
cell
These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma.
neuron
The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
MESH:A08.663
MESH:D009474
http://en.wikipedia.org/wiki/Neuron
A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
BTO:0000775
CALOHA:TS-0583
FMA:62863
VHOG:0001535
cell
Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)
lymphocyte
true
A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
GOC:add
ISBN:0683073696
ISBN:0781735149
cell
animal cell
A mesenchymal stem cell capable of developing into blood vessel endothelium.
angioblast
chondroplast
cell
These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive.
angioblastic mesenchymal cell
true
A mesenchymal stem cell capable of developing into blood vessel endothelium.
GOC:dsd
GOC:tfm
PMID:12768659
A stem cell that can give rise to cell types of the body other than those of the germ-line.
CALOHA:TS-2086
FMA:63368
cell
somatic stem cell
true
A stem cell that can give rise to cell types of the body other than those of the germ-line.
GO:0048103
An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
BTO:0000751
CALOHA:TS-0549
FMA:62852
immune cell
leucocyte
white blood cell
cell
leukocyte
true
An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
GOC:add
GOC:tfm
ISBN:978-0-323-05290-0
A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage.
pro-T lymphocyte
progenitor T cell
DN1 cell
DN1 thymocyte
TN1 cell
cell
pro-T cell
true
A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage.
GOC:add
ISBN:0781735149
A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.
BTO:0000725
CALOHA:TS-0448
MPP
hemopoietic progenitor cell
cell
Markers differ between mouse and human.
hematopoietic multipotent progenitor cell
true
A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.
GOC:add
GOC:tfm
PMID:19022770
A progenitor cell restricted to the lymphoid lineage.
lymphoid progenitor cell
BTO:0004731
CALOHA:TS-2025
FMA:70338
cell
Note that this is a class of cell types, not an identified single cell type.
lymphoid lineage restricted progenitor cell
true
A progenitor cell restricted to the lymphoid lineage.
GOC:add
GOC:tfm
A leukocyte with a single non-segmented nucleus in the mature form.
BTO:0000878
CALOHA:TS-0768
FMA:86713
mononuclear leukocyte
peripheral blood mononuclear cell
cell
mononuclear cell
true
A leukocyte with a single non-segmented nucleus in the mature form.
GOC:add
A cell of a hematopoietic lineage.
BTO:0000574
CALOHA:TS-2017
FMA:70366
FMA:83598
haematopoietic cell
haemopoietic cell
hemopoietic cell
cell
hematopoietic cell
A cell of a hematopoietic lineage.
GOC:add
GO_REF:0000031
A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers.
tmeehan
2010-01-06T03:43:27Z
cell
hematopoietic oligopotent progenitor cell, lineage-negative
A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers.
GOC:tfm
PMID:19022770
A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells.
tmeehan
2010-01-06T03:43:20Z
cell
hematopoietic lineage restricted progenitor cell
true
A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells.
GOC:tfm
PMID:19022770
A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers.
tmeehan
2010-01-06T03:43:27Z
cell
This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060).
hematopoietic oligopotent progenitor cell
true
A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers.
GOC:tfm
PMID:19022770
A cell containing at least one nucleus.
tmeehan
2010-09-07T03:32:33Z
FMA:67513
cell
nucleate cell
A cell containing at least one nucleus.
GOC:tfm
A cell that is part of the nervous system.
tmeehan
2010-09-15T01:34:57Z
CALOHA:TS-2040
FMA:70333
cell
neural cell
A cell that is part of the nervous system.
GOC:tfm
ISBN:0618947256
A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.
tmeehan
2010-09-15T03:01:54Z
CL:1000406
CALOHA:TS-2096
FMA:63875
cell
connective tissue cell
true
A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.
GOC:tfm
ISBN:0618947256
A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell).
tmeehan
2010-09-24T09:44:42Z
BTO:0001268
FMA:72300
WBbt:0008378
cell
somatic cell
A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell).
GOC:tfm
ISBN:0721662544
Any hematopoietic cell that is a precursor of some other hematopoietic cell type.
hematopoietic precursor cell
Any hematopoietic cell that is a precursor of some other hematopoietic cell type.
GOC:dos
A cell that, by division or terminal differentiation, can give rise to other cell types.
Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell.
precursor cell
A cell that, by division or terminal differentiation, can give rise to other cell types.
GOC:dos
An interneuron of the hippocampus.
FMA:84777
cl
hippocampal interneuron
An interneuron of the hippocampus.
GOC:pr
quality
Quality
the ambient temperature of this portion of air
the color of a tomato
the length of the circumference of your waist
the mass of this piece of gold.
the shape of your nose
the shape of your nostril
a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]
BFO:0000019
quality
a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]
PATO:0000125
mass
PATO:0002193
charge
material
MaterialEntity
a flame
a forest fire
a human being
a hurricane
a photon
a puff of smoke
a sea wave
a tornado
an aggregate of human beings.
an energy wave
an epidemic
the undetached arm of a human being
An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60
BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.
BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.
A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]
BFO:0000040
material entity
A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]
A particle smaller than an atom.
CHEBI:36342
chebi_ontology
subatomic particles
subatomic particle
subatomic particles
ChEBI
1
A material entity consisting of exactly one atomic nucleus and the electron(s) orbiting it.
This atom is closely related to ChEBI's atom, but not exactly equivalent to.
atom
A nucleus is the positively charged central portion of an atom, excluding the orbital electrons.
CHEBI:33252
nucleus
chebi_ontology
Atomkern
Kern
noyau
noyau atomique
nuclei
nucleo
nucleo atomico
nucleus atomi
Some people may be uncomfortable calling every proton an atomic nucleus
This is equivalent to CHEBI:33252
atomic nucleus
nucleus
IUPAC
Atomkern
ChEBI
Kern
ChEBI
noyau
IUPAC
noyau atomique
ChEBI
nuclei
ChEBI
nucleo
IUPAC
nucleo atomico
ChEBI
nucleus atomi
ChEBI
A material entity that consists of two or more atoms that are all connected via covalent bonds such that any atom can be transitively connected with any other atom.
CHEBI:23367
molecular entity
chebi_ontology
entidad molecular
entidades moleculares
entite moleculaire
molecular entities
molekulare Entitaet
This molecular entity is different than ChEBI's 'molecular entity'.
We would like to have cardinality restrictions on the logic, but there are some technical limitations.
molecular entity
molecular entity
IUPAC
entidad molecular
IUPAC
entidades moleculares
IUPAC
entite moleculaire
IUPAC
molecular entities
IUPAC
molekulare Entitaet
ChEBI
CHEBI:16541
CHEBI:36080
PR:000000001
protein
PMID:18089833.Cancer Res. 2007 Dec 15;67(24):12018-25. "...Epithelial cells were harvested from histologically confirmed adenocarcinomas .."
A material entity that has a plasma membrane and results from cellular division.
cell and encapsulating structures
CALOHA:TS-2035
CL:0000000
FMA:68646
GO:0005623
KUPO:0000002
NIF_Subcellular:sao1813327414
VHOG:0001533
WBbt:0004017
Wikipedia:Cell_(biology)
XAO:0003012
cell
cellular_component
CL and GO definitions of cell differ based on inclusive or exclusive of cell wall, etc.
The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one).
We struggled with this definition. We are worried about circularity. We also considered requiring the capability of metabolism.
cell
A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment).
CARO:0000013
CL:0000003
cell in vivo
cell
To accommodate unicellular organisms better, 'cell in vivo' has been re-labeled 'native cell' to better represent its intended meaning - that is, that it is a cell in the context of a multicellular organism or in a natural environment. 'Native' is intended to contrast with 'in vitro', which refers to cells or other biological entities that have been intentionally placed in a controlled, non-natural setting for the purpose of study or manipulation. (MAH 1.12.12).
native cell
A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment).
CARO:mah
A material entity consisting of at least two macromolecular entities derived from a cell as parts, and that has a function for the cell.
Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes.
Overlaps with some cellular components from GO
subcellular structure
organism
animal
fungus
plant
virus
A material entity that is a maximal functionally integrated unit that develops from a program encoded in a genome.
10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms')
13-02-2009:
OBI doesn't take position as to when an organism starts or ends being an organism - e.g. sperm, foetus.
This issue is outside the scope of OBI.
GROUP: OBI Biomaterial Branch
WEB: http://en.wikipedia.org/wiki/Organism
CARO:0001010
GC_ID:1
NCBITaxon:1
OBI:0100026
ncbi_taxonomy
all
"Maximal functionally integrated unit" is intended to express unity, which Barry considers synonymous with BFO 'object'.
Includes virus - we will later have a class for cellular organisms.
organism
all
organization
PMID: 16353909.AAPS J. 2005 Sep 22;7(2):E274-80. Review. The joint food and agriculture organization of the United Nations/World Health Organization Expert Committee on Food Additives and its role in the evaluation of the safety of veterinary drug residues in foods.
An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members.
An organization is a continuant entity which can play roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members.
BP: The definition summarizes long email discussions on the OBI developer, roles, biomaterial and denrie branches. It leaves open if an organization is a material entity or a dependent continuant, as no consensus was reached on that. The current placement as material is therefore temporary, in order to move forward with development. Here is the entire email summary, on which the definition is based:
1) there are organization_member_roles (president, treasurer, branch
editor), with individual persons as bearers
2) there are organization_roles (employer, owner, vendor, patent holder)
3) an organization has a charter / rules / bylaws, which specify what roles
there are, how they should be realized, and how to modify the
charter/rules/bylaws themselves.
It is debatable what the organization itself is (some kind of dependent
continuant or an aggregate of people). This also determines who/what the
bearer of organization_roles' are. My personal favorite is still to define
organization as a kind of 'legal entity', but thinking it through leads to
all kinds of questions that are clearly outside the scope of OBI.
Interestingly enough, it does not seem to matter much where we place
organization itself, as long as we can subclass it (University, Corporation,
Government Agency, Hospital), instantiate it (Affymetrix, NCBI, NIH, ISO,
W3C, University of Oklahoma), and have it play roles.
This leads to my proposal: We define organization through the statements 1 -
3 above, but without an 'is a' statement for now. We can leave it in its
current place in the is_a hierarchy (material entity) or move it up to
'continuant'. We leave further clarifications to BFO, and close this issue
for now.
PERSON: Alan Ruttenberg
PERSON: Bjoern Peters
PERSON: Philippe Rocca-Serra
PERSON: Susanna Sansone
GROUP: OBI
OBI:0000245
Should revisit if we can place outside of material entity - a collection of roles.
organization
processed material
Examples include gel matrices, filter paper, parafilm and buffer solutions, mass spectrometer, tissue samples
A material entity processed by human activity with an intent to produce
PERSON: Alan Ruttenberg
OBI:0000047
processed material entity
BFO:0000041
immaterial entity
BFO:0000017
realizable
BFO:0000015
process
planned process
Injecting mice with a vaccine in order to test its efficacy
A process that realizes a plan which is the concretization of a plan specification.
'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.)
We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some
objectives is a planned process.
Bjoern Peters
branch derived
6/11/9: Edited at workshop. Used to include: is initiated by an agent
This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call)
OBI:0000011
completely executed planned process
A process that emerges from two or more causally-connected macromolecular activities and has evolved to achieve a biological objective.
janelomax
2012-09-19T15:05:24Z
GO:0000004
GO:0007582
GO:0044699
GO:0008150
Wikipedia:Biological_process
biological process
physiological process
biological_process
single organism process
single-organism process
A biological process is an evolved process
Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.
biological process
A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process.
GO:0005554
GO:0003674
molecular function
molecular_function
Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.
This is the same as GO molecular function
gene product or complex activity
A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process.
GOC:pdt
CHEBI:24867
chebi_ontology
monoatomic ions
monoatomic ion
monoatomic ions
ChEBI
A chemical entity constituting the smallest component of an element having the chemical properties of the element.
CHEBI:22671
CHEBI:23907
CHEBI:33250
atom
chebi_ontology
atome
atomo
atoms
atomus
element
elements
uncharged atom
atom
IUPAC
atome
IUPAC
atomo
IUPAC
atoms
ChEBI
atomus
ChEBI
element
ChEBI
elements
ChEBI
0
Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV.
-1
0.000548579903
0.0
CHEBI:10545
COB:0000010
KEGG:C05359
PMID:21614077
Wikipedia:Electron
electron
chebi_ontology
Elektron
beta
beta(-)
beta-particle
e
e(-)
e-
negatron
nucleic acid polymer
PMID:21614077
Europe PMC
electron
ChEBI
electron
IUPAC
electron
KEGG_COMPOUND
Elektron
ChEBI
beta
IUPAC
beta(-)
ChEBI
beta-particle
IUPAC
e
IUPAC
e(-)
UniProt
e-
KEGG_COMPOUND
negatron
IUPAC
PCO:0000000
collection of organisms
BFO:0000029
site
The conclusion that a gene is upregulated in a tissue sample based on the band intensity in a western blot. The conclusion that a patient has a infection based on measurement of an elevated body temperature and reported headache. The conclusion that there were problems in an investigation because data from PCR and microarray are conflicting.
The following are NOT conclusions based on data: data themselves; results from pure mathematics, e.g. "13 is prime".
An information content entity that is inferred from data.
In the Philly 2013 workshop, we recognized the limitations of "conclusion textual entity", and we introduced this as more general. The need for the 'textual entity' term going forward is up for future debate.
Group:2013 Philly Workshop group
Group:2013 Philly Workshop group
OBI:0001909
conclusion based on data
IAO:0000030
Pier: 'data, information or knowledge'. OR 'representation
information
A process in which includes the components of an environmental system as participants.
ENVO:02500000
This is a convenience class for organisation and should not be used for annotation.
environmental process
An environmental system which includes both living and non-living components.
LTER:173
ENVO:01001110
This class will be primarily filled by inference, any environmental system which necessarily includes living parts should be autoclassified here.
ecosystem
An environmental system which includes both living and non-living components.
https://en.wikipedia.org/wiki/Ecosystem
LTER:173
https://vocab.lternet.edu/vocab/vocab/index.php?tema=173&/ecosystems
A material part of an astronomical body.
ENVO:01000813
envoAstro
envoPolar
geophysical entity
IAO:0000033
directive information entity
gene product
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0043234
GO:0032991
macromolecular complex
macromolecule complex
protein containing complex
protein complex
protein-protein complex
cellular_component
A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole.
This is not covalently bonded, which conflicts with changes to the parent definition.
protein-containing macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GOC:dos
GOC:mah
IAO:0000005
objective specification
action specification
IAO:0000104
plan specification
A complex of two or more molecular entities that are not covalently bound.
complex of molecular entities
>=2 parts (not we cannot use cardinality with transitive properties)
A process that is initiated by an agent who intends to carry out a plan to achieve an objective through one or more actions as described in a plan specification.
Should we create agent?
planned process
IAO:0000310
document
IAO:0000027
data item
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0005634
NIF_Subcellular:sao1702920020
Wikipedia:Cell_nucleus
cell nucleus
horsetail nucleus
cellular_component
cell nucleus
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GOC:go_curators
horsetail nucleus
GOC:al
GOC:mah
GOC:vw
PMID:15030757
assay
Assay the wavelength of light emitted by excited Neon atoms. Count of geese flying over a house.
A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies.
12/3/12: BP: the reference to the 'physical examination' is included to point out that a prediction is not an assay, as that does not require physical examiniation.
PlanAndPlannedProcess Branch
measuring
scientific observation
OBI branch derived
study assay
any method
OBI:0000070
assay
data transformation
The application of a clustering protocol to microarray data or the application of a statistical testing method on a primary data set to determine a p-value.
A planned process that produces output data from input data.
Elisabetta Manduchi
Helen Parkinson
James Malone
Melanie Courtot
Philippe Rocca-Serra
Richard Scheuermann
Ryan Brinkman
Tina Hernandez-Boussard
data analysis
data processing
Branch editors
OBI:0200000
data transformation
investigation
Lung cancer investigation using expression profiling, a stem cell transplant investigation, biobanking is not an investigation, though it may be part of an investigation
a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s).
Bjoern Peters
OBI branch derived
Could add specific objective specification
Following OBI call November 2012,26th: it was decided there was no need for adding "achieves objective of drawing conclusion" as existing relations were providing equivalent ability. this note closes the issue and validates the class definition to be part of the OBI core
editor = PRS
study
OBI:0000066
investigation
material processing
A cell lysis, production of a cloning vector, creating a buffer.
A planned process which results in physical changes in a specified input material
PERSON: Bjoern Peters
PERSON: Frank Gibson
PERSON: Jennifer Fostel
PERSON: Melanie Courtot
PERSON: Philippe Rocca Serra
material transformation
OBI branch derived
OBI:0000094
material processing
BFO:0000016
disposition
BFO:0000034
function
plan
The plan of researcher X to perform an experiment according to a protocol.
A plan is a realizable entity that is the inheres in a bearer who is committed to realizing it as a planned process.
This class is included to make clear how the plan specification, the plan, and the planned process relate. OBI will however only subclass and work under the 'plan specification', and 'planned process' class, as we want to avoid to get deep into discussions of 'intend' etc.
AR, BP, JM, MC, PRS
branch derived
OBI:0000260
plan
BFO:0000023
role
CARO:0010004
GC_ID:1
NCBITaxon:131567
ncbi_taxonomy
biota
cellular organism
biota
OBI:0000067
evaluant role
http://purl.obolibrary.org/obo/IAO_0000015
Pier 'representational entity'
This captures: pattern of writing in a book; neural state in the brain, electronic charges in computer memory etc
information representation
http://purl.obolibrary.org/obo/IAO_0000109
measurement datum
physical information carrier
sdc
SpecificallyDependentContinuant
Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key
of one-sided specifically dependent continuants: the mass of this tomato
of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.
the disposition of this fish to decay
the function of this heart: to pump blood
the mutual dependence of proton donors and acceptors in chemical reactions [79
the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction
the pink color of a medium rare piece of grilled filet mignon at its center
the role of being a doctor
the shape of this hole.
the smell of this portion of mozzarella
A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])
b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
(iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004]
(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]
BFO:0000020
characteristic
https://github.com/OBOFoundry/COB/issues/65
https://github.com/oborel/obo-relations/pull/284
b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])
b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
per discussion with Barry Smith
(iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004]
(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]
Cytoplasm that exhibits molecular interaction for acidic dyes under specific pH conditions.
tmeehan
2010-05-25T01:36:34Z
cell
neutrophillic cytoplasm
Cytoplasm that exhibits molecular interaction for acidic dyes under specific pH conditions.
GOC:tfm
A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.
tmeehan
2009-12-23T10:53:24Z
cell
increased nucleus size
A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.
GOC:tfm
https://en.wikipedia.org/wiki/Geographic_feature
macroscopic spatial feature
envoPolar
This class is being depopulated and will be filled only with inferred subclasses. Please do not use this for direct annotation, favouring instead a more descriptive subclass.
geographic feature
An anthropogenic geographic feature is a geographic feature resulting from the influence of human beings on nature.
FTT:78
TGN:50001
man-made feature
manmade feature
anthropogenic geographic feature
An anthropogenic geographic feature is a geographic feature resulting from the influence of human beings on nature.
ORCID:0000-0002-4366-3088
A geographical feature associated with water.
FTT:131
FTT:280
FTT:711
FTT:761
FTT:824
FTT:825
FTT:826
FTT:827
FTT:828
FTT:829
Geonames:H.OVF
fluvial feature
envoPolar
hydrographic feature
A geographical feature associated with water.
MA:ma
fluvial feature
ADL:FTT
A marine water body which is constitutes the majority of an astronomical body's hydrosphere.
LTER:695
EcoLexicon:ocean
FTT:1019
FTT:943
Geonames:H.OCN
SWEETRealm:Ocean
TGN:21102
https://en.wikipedia.org/wiki/Ocean
Ocean
ocean
ocean region
envoMarine
envoPolar
ocean
LTER:695
https://vocab.lternet.edu/vocab/vocab/index.php?tema=695&/oceans
Ocean
NASA:earthrealm
ocean
Geonames:feature
ocean region
ADL:FTT
A large expanse of saline water usually connected with an ocean.
EcoLexicon:sea
FTT:233
FTT:830
Geonames:H.SEA
TGN:21103
https://en.wikipedia.org/wiki/Sea
Sea
sea
channel
closed sea
marginal sea
open sea
open sound
open water
envoMarine
envoPolar
sea
A large expanse of saline water usually connected with an ocean.
https://en.wikipedia.org/wiki/Sea
Sea
NASA:earthrealm
sea
ADL:FTT
sea
Geonames:feature
closed sea
USGS:SDTS
marginal sea
USGS:SDTS
open sea
USGS:SDTS
open sound
USGS:SDTS
open water
USGS:SDTS
A geographical feature associated with water with a halinity above 30 ppt (roughly 35 g/L).
ENVO
saline hydrographic feature
A geographical feature associated with water with a halinity above 30 ppt (roughly 35 g/L).
https://en.wikipedia.org/wiki/Salinity
A lake whose water contains a considerable concentration of dissolved salts.
FTT:221
FTT:907
Geonames:H.LKN
Geonames:H.LKSN
TGN:21116
https://en.wikipedia.org/wiki/Saline_lake
salt lake
salina
soda lake
saline lake
A lake whose water contains a considerable concentration of dissolved salts.
MA:ma
salt lake
USGS:SDTS
salina
USGS:SDTS
A body of water or other liquid of considerable size contained in a depression on a landmass.
LTER:278
EcoLexicon:lake
FTT:221
FTT:704
FTT:909
Geonames:H.LK
Geonames:H.LKS
SPIRE:Lake_or_pond
SWEETRealm:Lake
TGN:21114
TGN:21115
catch basin
open water
tarn
broad
llyn
loch
lochan
lough
mere
mortlake
pasteuer lake
envoPolar
lake
A body of water or other liquid of considerable size contained in a depression on a landmass.
https://en.wikipedia.org/wiki/Lake
LTER:278
https://vocab.lternet.edu/vocab/vocab/index.php?tema=278&/lakes
catch basin
USGS:SDTS
open water
USGS:SDTS
tarn
ADL:FTT
lochan
ADL:FTT
mortlake
USGS:SDTS
pasteuer lake
USGS:SDTS
Place or area with clustered or scattered buildings and a permanent human population.
place
FTT:1097
FTT:33
Geonames:P.PPL
Geonames:P.PPLS
TGN:22201
TGN:83002
https://en.wikipedia.org/wiki/Populated_place
inhabited place
populated place
populated places
settlement
ENVO
inhabited region
populated locality
populated place
Place or area with clustered or scattered buildings and a permanent human population.
USGS:http://mapping.usgs.gov/www/ti/GNIS/gnis_users_guide_appendixc.html
place
USGS:SDTS
inhabited place
Getty:TGN
populated place
Geonames:feature
populated places
Geonames:feature
settlement
USGS:SDTS
An accumulation of water of varying size.
hydrographic feature
EcoLexicon:waterbody
FTT:131
FTT:280
FTT:827
SWEETRealm:BodyOfWater
TGN:21100
TGN:21101
https://en.wikipedia.org/wiki/Water_body
aquatic feature
bodies of water
body of water
waterbody
https://en.wikipedia.org/wiki/ The term body of water most often refers to large accumulations of water, such as oceans, seas, and lakes, but it includes smaller pools of water such as ponds, wetlands, or more rarely, puddles. A body of water does not have to be still or contained; Rivers, streams, canals, and other geographical features where water moves from one place to another are also considered bodies of water.
water body
An accumulation of water of varying size.
https://en.wikipedia.org/wiki/Body_of_water
hydrographic feature
ADL:FTT
bodies of water
Getty:TGN
body of water
ADL:FTT
body of water
Getty:TGN
A construction that has been assembled by deliberate human effort.
"constructed" should probably be made something like a quality and this class obsoleted or filled only by inference
constructed feature
human construction
A construction that has been assembled by deliberate human effort.
MA:ma
A permanent walled and roofed construction.
FTT:42
Geonames:S.BLDG
LTER:76
TGN:51011
https://en.wikipedia.org/wiki/Building
BUILDING
building
building
A permanent walled and roofed construction.
USGS:SDTS
BUILDING
USGS:SDTS
building
Geonames:feature
An excavation in the Earth for the purpose of extracting earth materials.
EcoLexicon:mine
FTT:14
FTT:968
Geonames:L.MNA
Geonames:S.MN
TGN:54211
TGN:54212
mine
An excavation in the Earth for the purpose of extracting earth materials.
USGS:SDTS
https://en.wikipedia.org/wiki/Mine
A landform that extends above the surrounding terrain in a limited area.
EcoLexicon:mountain
FTT:1000
FTT:118
FTT:460
FTT:548
FTT:713
FTT:896
FTT:993
Geonames:T.MT
Geonames:T.MTS
SWEETRealm:Mountain
TGN:21430
TGN:21434
https://en.wikipedia.org/wiki/Mountain
Mountain
mountains
envoPolar
A mountain is generally steeper than a hill, but there is no universally accepted standard definition for the height of a mountain or a hill although a mountain usually has an identifiable summit. The USGS had previously defined mountains as localised elevations of more than 300 meters; however, the organisation has accepted there are no technical definitions in the US. In ENVO, we primarily use the UNEP-WCMC classification to be compliant with SDG monitoring, but we can host other classifications on request: http://www.fao.org/sustainable-development-goals/indicators/1542/en/
mountain
A landform that extends above the surrounding terrain in a limited area.
https://en.wikipedia.org/wiki/Mountain#United_Kingdom
https://www.unep-wcmc.org/resources-and-data/mountain-watch--environmental-change-sustainable-development-in-mountains
https://www.usgs.gov/faqs/what-difference-between-mountain-hill-and-peak-lake-and-pond-or-river-and-creek
Mountain
NASA:earthrealm
mountains
Geonames:feature
A rounded elevation of limited extent rising above the surrounding land with local relief of less than 300m.
EcoLexicon:hill
FTT:118
FTT:468
FTT:713
FTT:799
FTT:896
Geonames:T.HLL
Geonames:T.HLLS
SWEETRealm:Hill
TGN:21437
TGN:21438
https://en.wikipedia.org/wiki/Hill
ENVO
cerro
foothill
hill
hillock
hills
knoll
mount
mountain
hill
A rounded elevation of limited extent rising above the surrounding land with local relief of less than 300m.
Geonames:feature
foothill
ADL:FTT
foothill
USGS:SDTS
hill
Geonames:feature
hillock
USGS:SDTS
hills
Geonames:feature
knoll
USGS:SDTS
mount
USGS:SDTS
mountain
ADL:FTT
A region of general uniform slope, comparatively level, and of considerable extent.
EcoLexicon:plain
FTT:707
FTT:874
FTT:926
Geonames:T.PLN
SWEETRealm:Plain
TGN:21461
https://en.wikipedia.org/wiki/Plain
PLAIN
Plain
plain
interfluve
llanos
outwash plain
plain
A region of general uniform slope, comparatively level, and of considerable extent.
USGS:SDTS
PLAIN
USGS:SDTS
Plain
NASA:earthrealm
plain
Geonames:feature
interfluve
ADL:FTT
llanos
ADL:FTT
outwash plain
USGS:SDTS
An area of flat, low-lying land adjacent to a coast and separated from the interior by other features.
EcoLexicon:coastal_plain
EcoLexicon:coastal_zone
FTT:240
FTT:499
FTT:500
FTT:501
FTT:502
FTT:503
FTT:504
SWEETRealm:CoastalPlain
https://en.wikipedia.org/wiki/Coastal_plain
ENVO
coastal plain
An area of flat, low-lying land adjacent to a coast and separated from the interior by other features.
https://en.wikipedia.org/wiki/Coastal_plain
A landform consisting of loose rock particles such as sand, gravel, shingle, pebbles, cobble, or even shell fragments along the shoreline of a body of water.
EcoLexicon:beach
EcoLexicon:to_beach
FTT:237
FTT:239
Geonames:T.BCH
Geonames:T.BCHS
SWEETRealm:Beach
TGN:21482
https://en.wikipedia.org/wiki/Beach
Beach
beach berm
lagoon beach
beach
beaches
foreshore flats
rivage
strand
beach
A landform consisting of loose rock particles such as sand, gravel, shingle, pebbles, cobble, or even shell fragments along the shoreline of a body of water.
https://en.wikipedia.org/wiki/Beach
Beach
NASA:earthrealm
beach berm
USGS:SDTS
lagoon beach
USGS:SDTS
beach
Geonames:feature
beaches
Geonames:feature
foreshore flats
USGS:SDTS
rivage
USGS:SDTS
strand
ADL:FTT
strand
USGS:SDTS
A landform consisting of loose rock particles such as sand, gravel, shingle, pebbles, cobble, or even shell fragments along the shoreline of a sea.
https://en.wikipedia.org/wiki/Strand
strand
sea beach
A landform consisting of loose rock particles such as sand, gravel, shingle, pebbles, cobble, or even shell fragments along the shoreline of a sea.
https://en.wikipedia.org/wiki/Beach
A landform consisting of loose rock particles such as sand, gravel, shingle, pebbles, cobble, or even shell fragments along the shoreline of a lake.
ENVO
lacustrine beach
A landform consisting of loose rock particles such as sand, gravel, shingle, pebbles, cobble, or even shell fragments along the shoreline of a lake.
MA:ma
A part of an astronomical body associated with a volcano - an opening, or rupture, in that body's surface or crust - which allows hot, molten rock, ash and gases to escape from deep below the surface.
FTT:591
TGN:21407
volcanic landform
volcanic feature
A part of an astronomical body associated with a volcano - an opening, or rupture, in that body's surface or crust - which allows hot, molten rock, ash and gases to escape from deep below the surface.
https://en.wikipedia.org/wiki/Volcano
volcanic landform
Getty:TGN
A region rendered barren or partially barren by environmental extremes, especially by low rainfall.
EcoLexicon:desert
FTT:1
FTT:188
Geonames:T.DSRT
LTER:147
SWEETRealm:Desert
TGN:21201
https://en.wikipedia.org/wiki/Desert
arid region
envoPolar
desert area
A region rendered barren or partially barren by environmental extremes, especially by low rainfall.
USGS:SDTS
arid region
ADL:FTT
A depression which has been formed as a result of erosion by water or ice and which is low-lying, bordered by higher ground, and especially elongate.
EcoLexicon:valley
FTT:158
FTT:166
FTT:418
FTT:761
FTT:811
FTT:949
Geonames:T.GRGE
Geonames:T.VAL
Geonames:T.VALS
SWEETRealm:Valley
TGN:21425
TGN:21451
TGN:21452
TGN:21453
chasm
coulee
dale
glacial gorge
glacial trough
gulch
gully
median valley
shelf valley
glen
goe
gorge
graben
hollow
lavaka
moat
ravine
re-entrant
seachannel
strath
trench
vale
water gap
Valleys are typically located between hills our mountains.
valley
A depression which has been formed as a result of erosion by water or ice and which is low-lying, bordered by higher ground, and especially elongate.
ADL:FTT
https://en.wikipedia.org/wiki/Valley
chasm
USGS:SDTS
coulee
USGS:SDTS
dale
USGS:SDTS
glacial gorge
USGS:SDTS
glacial trough
USGS:SDTS
gulch
USGS:SDTS
gully
Getty:TGN
gully
USGS:SDTS
median valley
ADL:FTT
median valley
Geonames:feature
shelf valley
Geonames:feature
glen
ADL:FTT
glen
USGS:SDTS
goe
USGS:SDTS
gorge
Geonames:feature
gorge
USGS:SDTS
graben
USGS:SDTS
hollow
ADL:FTT
hollow
Getty:TGN
hollow
USGS:SDTS
moat
USGS:SDTS
ravine
USGS:SDTS
re-entrant
USGS:SDTS
seachannel
USGS:SDTS
strath
USGS:SDTS
trench
USGS:SDTS
water gap
USGS:SDTS
EcoLexicon:fan
EcoLexicon:platform
EcoLexicon:ravine
FTT:1020
FTT:1137
FTT:1176
FTT:1193
FTT:1194
FTT:1195
FTT:1196
FTT:5
FTT:810
FTT:984
Geonames:FRKU
Geonames:FRSU
Geonames:MDVU
Geonames:PLFU
Geonames:RAVU
Geonames:RMPU
Geonames:U.BSNU
Geonames:U.EDGU
Geonames:U.ESCU
Geonames:U.FANU
Geonames:U.FLTU
Geonames:U.FURU
Geonames:U.GAPU
Geonames:U.GLYU
Geonames:U.HOLU
Geonames:U.LDGU
Geonames:U.LEVU
Geonames:U.PLNU
Geonames:U.PLTU
Geonames:U.PNLU
Geonames:U.PRVU
Geonames:U.RDGU
Geonames:U.RDSU
Geonames:U.RISU
Geonames:U.SDLU
Geonames:U.SHVU
Geonames:U.SILU
Geonames:U.SPRU
Geonames:U.TERU
Geonames:U.VALU
Geonames:U.VLSU
TGN:23001
TGN:23116
TGN:23117
TGN:23118
TGN:23135
TGN:23162
TGN:23181
TGN:23182
TGN:23183
TGN:23184
TGN:23188
TGN:23192
TGN:23193
TGN:23194
TGN:23195
TGN:23196
TGN:23211
TGN:23212
TGN:23301
TGN:23411
TGN:23412
TGN:23413
TGN:23415
TGN:23421
TGN:23423
TGN:23424
TGN:23431
TGN:23453
TGN:23461
TGN:23463
TGN:23467
TGN:23550
basin
escarpment
fan
flat
fork
forks
furrow
gap
gully
hole
hole (seafloor)
ledge
levee
median valley
moat (seafloor)
pinnacle
plain
plateau
platform
province
ramp
ramp (seafloor)
ravine
ridge
ridges
rise
rise (seafloor)
saddle
shelf edge
undersea bank
undersea basin
undersea bench
undersea cliff
undersea fan
undersea fork
undersea fracture zone
undersea furrow
undersea gap
undersea hole
undersea ledge
undersea levee
undersea median valley
undersea moat
undersea peak
undersea pinnacle
undersea plain
undersea platform
undersea ramp
undersea rise
undersea saddle
undersea shelf
undersea shelf edge
undersea shelf valley
undersea sill
undersea slope
undersea spur
undersea terrace
undersea tongue
undersea valley
ENVO
ocean floor feature
seafloor feature
sill
spur
subsea feature
terrace
tongue (seafloor)
underwater feature
valley
valleys
undersea feature
basin
Geonames:feature
escarpment
Geonames:feature
fan
Geonames:feature
flat
Geonames:feature
fork
Geonames:feature
forks
Geonames:feature
furrow
Geonames:feature
gap
Geonames:feature
gully
Geonames:feature
hole
Geonames:feature
hole (seafloor)
ADL:FTT
ledge
Geonames:feature
levee
Geonames:feature
median valley
Geonames:feature
moat (seafloor)
ADL:FTT
pinnacle
Geonames:feature
plain
Geonames:feature
plateau
Geonames:feature
platform
Geonames:feature
province
Geonames:feature
ramp
Geonames:feature
ramp (seafloor)
ADL:FTT
ravine
Geonames:feature
ridge
Geonames:feature
ridges
Geonames:feature
rise
Geonames:feature
rise (seafloor)
ADL:FTT
saddle
Geonames:feature
shelf edge
Geonames:feature
undersea bank
Getty:TGN
undersea basin
Getty:TGN
undersea bench
Getty:TGN
undersea cliff
Getty:TGN
undersea fan
Getty:TGN
undersea fork
Getty:TGN
undersea fracture zone
Getty:TGN
undersea furrow
Getty:TGN
undersea gap
Getty:TGN
undersea hole
Getty:TGN
undersea ledge
Getty:TGN
undersea levee
Getty:TGN
undersea median valley
Getty:TGN
undersea moat
Getty:TGN
undersea peak
Getty:TGN
undersea pinnacle
Getty:TGN
undersea plain
Getty:TGN
undersea platform
Getty:TGN
undersea ramp
Getty:TGN
undersea rise
Getty:TGN
undersea saddle
Getty:TGN
undersea shelf
Getty:TGN
undersea shelf edge
Getty:TGN
undersea shelf valley
Getty:TGN
undersea sill
Getty:TGN
undersea slope
Getty:TGN
undersea spur
Getty:TGN
undersea terrace
Getty:TGN
undersea tongue
Getty:TGN
undersea valley
Getty:TGN
ocean floor feature
ADL:FTT
seafloor feature
ADL:FTT
sill
Geonames:feature
spur
Geonames:feature
subsea feature
ADL:FTT
terrace
Geonames:feature
tongue (seafloor)
ADL:FTT
underwater feature
ADL:FTT
valley
Geonames:feature
valleys
Geonames:feature
A vegetated area which is part of a tundra ecosystem.
EcoLexicon:tundra
FTT:151
FTT:152
Geonames:V.TUND
LTER:605
TGN:21611
Arctic land
TundraEcosystem
envoPolar
area of tundra
A vegetated area which is part of a tundra ecosystem.
Arctic land
ADL:FTT
https://en.wikipedia.org/wiki/Tundra
TundraEcosystem
NASA:earthrealm
A valley that no longer has a surface flow of water. Typically found in either Karst (limestone) or chalk terrain.
https://en.wikipedia.org/wiki/Dry_valley
ENVO
dry valley
A valley that no longer has a surface flow of water. Typically found in either Karst (limestone) or chalk terrain.
https://en.wikipedia.org/wiki/Dry_valley
A ridge of rocks, lying near the surface of the sea, which may be visible at low tide, but is usually covered by water.
EcoLexicon:reef
FTT:202
FTT:203
FTT:729
Geonames:H.RF
Geonames:U.RFSU
Geonames:U.RFU
SPIRE:Reef
TGN:21479
https://en.wikipedia.org/wiki/Reef
REEF
atoll reef
bank reef
barrier reef
fringing reef
shore reef
submerged reef
ledge
reef
reef flat
reefs
rocky reef
A ridge of rocks, lying near the surface of the sea, which may be visible at low tide, but is usually covered by water.
USGS:SDTS
REEF
USGS:SDTS
atoll reef
USGS:SDTS
bank reef
USGS:SDTS
barrier reef
ADL:FTT
barrier reef
USGS:SDTS
fringing reef
ADL:FTT
fringing reef
USGS:SDTS
shore reef
USGS:SDTS
submerged reef
USGS:SDTS
ledge
USGS:SDTS
reef
Geonames:feature
reef flat
USGS:SDTS
reefs
Geonames:feature
A hydrographic feature characterized by the dominance of snow or ice.
EcoLexicon:ice
FTT:648
SWEETRealm:LandIce
TGN:21410
glacer
Ice
LandIce
glacial landform
glacier feature
envoPolar
Likely to be depopulated and "glacial" made into a quality or similar.
glacial feature
A hydrographic feature characterized by the dominance of snow or ice.
MA:ma
glacer
ADL:FTT
Ice
NASA:earthrealm
LandIce
NASA:earthrealm
glacial landform
Getty:TGN
glacier feature
ADL:FTT
A glacier which covers an area of greater than 50,000 square kilometers.
FTT:758
FTT:835
FTT:837
SWEETRealm:IceSheet
TGN:21147
https://en.wikipedia.org/wiki/Ice_sheet
Arctic pack
ICE FIELD
bay ice
continental glacier
continental ice
glacial tongue
ice field
ice mass
island ice
pack ice
polar ice
polar ice pack
rock glacier
shelf ice
envoPolar
This is not always classified as a glacier in the cryosphere community.
ice sheet
A glacier which covers an area of greater than 50,000 square kilometers.
https://en.wikipedia.org/wiki/Ice_sheet
Arctic pack
USGS:SDTS
ICE FIELD
USGS:SDTS
bay ice
USGS:SDTS
continental glacier
USGS:SDTS
continental ice
USGS:SDTS
glacial tongue
USGS:SDTS
ice field
ADL:FTT
ice mass
ADL:FTT
island ice
USGS:SDTS
pack ice
USGS:SDTS
polar ice
USGS:SDTS
polar ice pack
USGS:SDTS
rock glacier
USGS:SDTS
shelf ice
USGS:SDTS
This is not always classified as a glacier in the cryosphere community.
https://github.com/Vocamp/Virtual-Hackahon-on-Glacier-topic
An ice mass which is of sufficient mass that the action of gravity upon it overcomes the frictional forces holding it in place, causing it to deform and flow towards lower elevation.
http://orcid.org/0000-0002-3410-4655
glacial feature
EcoLexicon:glacier
FTT:648
FTT:756
Geonames:H.GLCR
TGN:21141
http://sweetontology.net/realmCryo/Glacier
Glacier
glacier
RockGlacier
rock glacier
envoPolar
The definition of glacier is highly variable. Two main issues exist: 1) Whether or not a mass of ice must currently show movement to be considered a glacier or not and 2) What is the relationship between ice sheets and glaciers (i.e., which is the parent in a parent/child relationship or whether they are distinct terms).
glacier
An ice mass which is of sufficient mass that the action of gravity upon it overcomes the frictional forces holding it in place, causing it to deform and flow towards lower elevation.
https://en.wikipedia.org/wiki/Glacier
glacial feature
ADL:FTT
Glacier
NASA:earthrealm
glacier
Geonames:feature
RockGlacier
NASA:earthrealm
rock glacier
USGS:SDTS
The definition of glacier is highly variable. Two main issues exist: 1) Whether or not a mass of ice must currently show movement to be considered a glacier or not and 2) What is the relationship between ice sheets and glaciers (i.e., which is the parent in a parent/child relationship or whether they are distinct terms).
https://orcid.org/0000-0003-4808-4736
Soil or rock and included ice or organic material at or below the freezing point of water (0 degrees Celsius or 32 degrees Fahrenheit) for two or more years.
EcoLexicon:permafrost
LTER:408
https://en.wikipedia.org/wiki/Permafrost
Permafrost
envoPolar
Ice is not always present, as may be in the case of nonporous bedrock, but it frequently occurs and it may be in amounts exceeding the potential hydraulic saturation of the ground material.
permafrost
Soil or rock and included ice or organic material at or below the freezing point of water (0 degrees Celsius or 32 degrees Fahrenheit) for two or more years.
https://en.wikipedia.org/wiki/Permafrost
Permafrost
NASA:earthrealm
Aragonite structures produced by living organisms, found in shallow, marine waters with little nutrients in the water.
LTER:127
EcoLexicon:coral_reef
FTT:202
FTT:547
FTT:729
Geonames:H.RFC
LTER:127
https://en.wikipedia.org/wiki/Coral_reef
CoralReef
coral reef
barrier reef
fringing reef
reef
coral reef
Aragonite structures produced by living organisms, found in shallow, marine waters with little nutrients in the water.
https://en.wikipedia.org/wiki/Coral_reef
LTER:127
https://vocab.lternet.edu/vocab/vocab/index.php?tema=127&/coral-reefs
CoralReef
NASA:earthrealm
coral reef
ADL:FTT
coral reef
Geonames:feature
coral reef
USGS:SDTS
fringing reef
ADL:FTT
fringing reef
USGS:SDTS
reef
USGS:SDTS
A hill of sand built by eolian processes.
mount
ridge
sandy area
EcoLexicon:dune
FTT:238
FTT:241
FTT:652
Geonames:T.DUNE
LTER:171
SWEETRealm:Dune
TGN:21419
TGN:21505
https://en.wikipedia.org/wiki/Dune
Dune
dune
sand dune
interdune trough
sand hill
dune
A hill of sand built by eolian processes.
https://en.wikipedia.org/wiki/Dune
mount
USGS:SDTS
ridge
USGS:SDTS
sandy area
ADL:FTT
sandy area
Geonames:feature
sandy area
Getty:TGN
Dune
NASA:earthrealm
dune
Geonames:feature
sand dune
USGS:SDTS
interdune trough
ADL:FTT
sand hill
USGS:SDTS
A landform elevated above the surrounding area.
LTER:177
SWEETRealm:Elevation
https://en.wikipedia.org/wiki/Elevation
elevation
A landform elevated above the surrounding area.
MA:ma
A part of an astronomical body which is primarily composed of a continuous volume of solid material, shaped by one or more environmental processes.
EcoLexicon:landform
EcoLexicon:landforms
FTT:754
FTT:96
SWEETRealm:Landform
TGN:21400
TGN:21401
geological feature
physiographic feature
solid astronomical body part
A part of an astronomical body which is primarily composed of a continuous volume of solid material, shaped by one or more environmental processes.
https://en.wikipedia.org/wiki/Landform
geological feature
ADL:FTT
Broken rock that appears at the bottom of crags, mountain cliffs or valley shoulders.
EcoLexicon:scree
FTT:1078
FTT:96
Geonames:T.TAL
SWEETRealm:Talus
TGN:21508
https://en.wikipedia.org/wiki/Scree
ENVO
TALUS
talus slope
scree
Broken rock that appears at the bottom of crags, mountain cliffs or valley shoulders.
https://en.wikipedia.org/wiki/Scree
TALUS
USGS:SDTS
talus slope
Geonames:feature
talus slope
Getty:TGN
The zone of an ocean below 200m, in which photosynthesis cannot occur due to the lack of light.
EcoLexicon:aphotic_zone
SWEETRealm:AphoticZone
https://en.wikipedia.org/wiki/Aphotic_zone
AphoticZone
envoMarine
envoPolar
marine aphotic zone
The zone of an ocean below 200m, in which photosynthesis cannot occur due to the lack of light.
https://en.wikipedia.org/wiki/Ocean
AphoticZone
NASA:earthrealm
The zone of the ocean below the bathypelagic zone, with its lowest boundary at about 6000m.
envoMarine
marine abyssalpelagic zone
The zone of the ocean below the bathypelagic zone, with its lowest boundary at about 6000m.
https://en.wikipedia.org/wiki/Ocean
A flat or very gently sloping areas of the deep ocean basin floor.
EcoLexicon:abyssal_plain
FTT:4
SPIRE:Abyssal
TGN:23302
https://en.wikipedia.org/wiki/Abyssal_plain
Abyssalplain
ENVO
abyssal feature
abyssal plain
A flat or very gently sloping areas of the deep ocean basin floor.
https://en.wikipedia.org/wiki/Abyssal_plain
Abyssalplain
NASA:earthrealm
abyssal feature
ADL:FTT
An opening, or rupture, in the Earth's surface or crust, which allows hot, molten rock, ash and gases to escape from deep below the surface.
mount
EcoLexicon:volcano
FTT:592
Geonames:T.VLC
TGN:21406
https://en.wikipedia.org/wiki/Volcano
Volcano
volcano
volcano
An opening, or rupture, in the Earth's surface or crust, which allows hot, molten rock, ash and gases to escape from deep below the surface.
https://en.wikipedia.org/wiki/Volcano
mount
USGS:SDTS
Volcano
NASA:earthrealm
volcano
Geonames:feature
A valley that contains, or contained, a glacier and was formed by glacial activity. Typically U-shaped in cross-section.
https://en.wikipedia.org/wiki/Glacial_valley
ENVO
valley
envoPolar
glacial valley
A valley that contains, or contained, a glacier and was formed by glacial activity. Typically U-shaped in cross-section.
MA:ma
valley
USGS:SDTS
The general region of indefinite width that extends from the sea inland to the first major change in terrain features.
EcoLexicon:coast
EcoLexicon:sea_coast
FTT:500
Geonames:L.CST
SPIRE:Coastal
SPIRE:Littoral
SWEETRealm:CoastalRegion
TGN:21483
https://en.wikipedia.org/wiki/Coast
coast line
coastal area
coastline
sea coast
The general region of indefinite width that extends from the sea inland to the first major change in terrain features.
USGS:SDTS
coastal area
USGS:SDTS
coastline
USGS:SDTS
That part of the land in immediate contact with a body of water including the area between high and low water lines.
coastal zone
EcoLexicon:shore
FTT:240
FTT:503
FTT:504
Geonames:T.SHOR
SWEETRealm:Shore
TGN:21481
https://en.wikipedia.org/wiki/Shore
SHORE
shore
shoreface
beach face
foreshore
inshore
rivage
seashore
strand
shore
That part of the land in immediate contact with a body of water including the area between high and low water lines.
USGS:SDTS
coastal zone
ADL:FTT
SHORE
USGS:SDTS
shore
Geonames:feature
shoreface
USGS:SDTS
beach face
USGS:SDTS
foreshore
USGS:SDTS
inshore
USGS:SDTS
rivage
USGS:SDTS
seashore
USGS:SDTS
strand
USGS:SDTS
A landform sunken or depressed below the surrounding area.
Clarify that this pertains to the planetary crust and create superclass for general topological depressions. https://github.com/EnvironmentOntology/envo/issues/486
EcoLexicon:depression
FTT:175
FTT:215
FTT:216
Geonames:T.DPR
Geonames:T.PAN
Geonames:T.PANS
SWEETRealm:Depression
TGN:21454
TGN:21497
TGN:21521
barrier basin
depression
non tidal basin
pan
pan (geologic)
pans
tidal basin
depression
A landform sunken or depressed below the surrounding area.
https://en.wikipedia.org/wiki/Depression_%28geology%29
barrier basin
USGS:SDTS
depression
Geonames:feature
non tidal basin
USGS:SDTS
pan
Geonames:feature
pan
Getty:TGN
pan (geologic)
ADL:FTT
pans
Geonames:feature
tidal basin
USGS:SDTS
An abiotic mesoscopic feature made of the mineral material of the crust of the Earth.
FTT:1010
FTT:145
Geonames:T.RK
Geonames:T.RKS
TGN:21444
piece of rock
An abiotic mesoscopic feature made of the mineral material of the crust of the Earth.
MA:ma
grain of sand
A piece of rock that is two millimeters (2mm) in its largest dimension (about 1/12 of an inch) and no more than 75 millimeters (about 3 inches).
piece of gravel
A piece of rock that is two millimeters (2mm) in its largest dimension (about 1/12 of an inch) and no more than 75 millimeters (about 3 inches).
https://en.wikipedia.org/wiki/Gravel
ENVO
grain of desert sand
ENVO
grain of beach sand
ENVO
grain of acid dune sand
ENVO
grain of sea sand
ENVO
grain of rocky sand
https://en.wikipedia.org/wiki/Coastal_dune
ENVO
coastal dune
The solid surface that underlies an ocean.
FTT:1020
https://en.wikipedia.org/wiki/Ocean_floor
ocean bed
ocean floor feature
ocean floor
The solid surface that underlies an ocean.
MA:ma
ocean floor feature
ADL:FTT
2
A biome is an ecosystem to which resident ecological communities have evolved adaptations.
LTER:809
EcoLexicon:biome
major habitat type
EcosytemType
There has been some concern raised (see Issue #143) about the usefulness of the assertion that organisms have evolved within a given biome. They may have evolved adaptations elsewhere and demonstrating one or the other is often not feasible. Consider relabelling to "environmental system determined by an ecological community" or similar.
biome
A biome is an ecosystem to which resident ecological communities have evolved adaptations.
DOI:10.1186/2041-1480-4-43
https://en.wikipedia.org/wiki/Biome
LTER:809
https://vocab.lternet.edu/vocab/vocab/index.php?tema=809&/biomes
major habitat type
WWF:Biome
EcosytemType
NASA:earthrealm
A biome which is primarily or completely situated on a landmass.
LTER:798
SPIRE:Terrestrial
terrestrial realm
terrestrial biome
A biome which is primarily or completely situated on a landmass.
https://en.wikipedia.org/wiki/Biome#Terrestrial_biomes
An aquatic biome which is determined by a marine water body.
SPIRE:Marine
marine realm
envoPolar
This biome includes open-ocean and unprotected coastal ecosystems, characterized by exposure to wave action, tidal fluctuation, and ocean currents as well as systems that largely resemble these. Water in the marine biome is generally within the salinity range of seawater: 30 to 38 ppt.
marine biome
An aquatic biome which is determined by a marine water body.
ISBN:978-0-618-45504-1
MA:ma
https://en.wikipedia.org/wiki/Ocean
A mountain or a hill.
EcoLexicon:dome
FTT:118
FTT:460
SWEETRealm:Dome
TGN:21439
https://en.wikipedia.org/wiki/Mount
MOUNT
cerrito
cerro
dome
hill
hillock
hummock
inselberg
knob
knoll
koppje
monadnock
mountain
rise
mount
A mountain or a hill.
USGS:SDTS
MOUNT
USGS:SDTS
cerrito
USGS:SDTS
cerro
ADL:FTT
cerro
USGS:SDTS
dome
USGS:SDTS
hill
USGS:SDTS
hillock
USGS:SDTS
hummock
Getty:TGN
hummock
USGS:SDTS
inselberg
USGS:SDTS
knob
USGS:SDTS
knoll
USGS:SDTS
koppje
USGS:SDTS
monadnock
USGS:SDTS
mountain
ADL:FTT
rise
USGS:SDTS
That part of the land in immediate contact with a sea, including the intertidal zone.
EcoLexicon:seashore
FTT:504
shore
sea shore
That part of the land in immediate contact with a sea, including the intertidal zone.
MA:ma
The portion of the ground surface which lies below water.
BOTTOM
EcoLexicon:bed
FTT:804
SWEETRealm:Bottom
https://en.wikipedia.org/wiki/Stream_bed
submerged bed
The portion of the ground surface which lies below water.
USGS:SDTS
BOTTOM
USGS:SDTS
A beach which is armoured with pebbles or small to medium sized cobbles.
https://en.wikipedia.org/wiki/Shingle_beach
pebble beach
ENVO
shingle beach
A beach which is armoured with pebbles or small to medium sized cobbles.
https://en.wikipedia.org/wiki/Shingle_beach
Incorporated populated place.
urban area
EcoLexicon:city
FTT:430
FTT:483
FTT:484
FTT:485
SWEETRealm:City
TGN:83020
TGN:83040
TGN:83043
https://en.wikipedia.org/wiki/City
ENVO
city
Incorporated populated place.
ADL:FTT
urban area
ADL:FTT
A rock is a naturally occurring solid aggregate of one or more minerals or mineraloids.
EcoLexicon:rock
FTT:1010
FTT:145
Geonames:T.RK
Geonames:T.RKS
SWEETRealm:Rock
TGN:21444
https://en.wikipedia.org/wiki/Rock
From https://en.wikipedia.org/wiki/ [A mineral] is different from a rock, which can be an aggregate of minerals or non-minerals and does not have a specific chemical composition. The exact definition of a mineral is under debate, especially with respect to the requirement a valid species be abiogenic, and to a lesser extent with regards to it having an ordered atomic structure.
rock
A rock is a naturally occurring solid aggregate of one or more minerals or mineraloids.
MA:ma
https://en.wikipedia.org/wiki/Rock_(geology)
Soil is an environmental material which is primarily composed of minerals, varying proportions of sand, silt, and clay, organic material such as humus, gases, liquids, and a broad range of resident micro- and macroorganisms.
The various 'has part' and 'has quality' relations may not hold true for all soils; however, I have yet to find counter examples. Require input from a pedologist or similar. [pbuttigieg]
regolith
LTER:535
SPIRE:Soil
SWEETRealm:Soil
https://en.wikipedia.org/wiki/Soil
'In engineering terms, soil is referred to as regolith, or loose rock material that lies above the 'solid geology'. Soil is commonly referred to as "earth" or "dirt"; technically, the term "dirt" should be restricted to displaced soil.' https://en.wikipedia.org/wiki/Soil
" The upper limit of soil is the boundary between soil and air, shallow water, live plants, or plant materials that have not begun to decompose. Areas are not considered to have soil if the surface is permanently covered by water too deep (typically more than 2.5 meters) for the growth of rooted plants.
The lower boundary that separates soil from the nonsoil underneath is most difficult to define. Soil consists of horizons near the Earth's surface that, in contrast to the underlying parent material, have been altered by the interactions of climate, relief, and living organisms over time. Commonly, soil grades at its lower boundary to hard rock or to earthy materials virtually devoid of animals, roots, or other marks of biological activity. For purposes of classification, the lower boundary of soil is arbitrarily set at 200 cm." Soil taxonomy, 2nd Ed., quoted in http://www.nrcs.usda.gov/wps/portal/nrcs/detail/soils/edu/?cid=nrcs142p2_054280
soil
Soil is an environmental material which is primarily composed of minerals, varying proportions of sand, silt, and clay, organic material such as humus, gases, liquids, and a broad range of resident micro- and macroorganisms.
https://en.wikipedia.org/wiki/Soil
A significant accumulation of water which is part of a marine biome.
body of marine water
marine waterbody
Ideas like "significant" are fuzzy and need to be modelled more accurately. The definition is a candidate for review.
marine water body
A solid astronomical body part which is part of the planetary surface between the peak of an elevation or the bottom of a depression and relatively flat surrounding land.
EcoLexicon:slope
SWEETRealm:Slope
https://en.wikipedia.org/wiki/Slope
flank
side
slope
A solid astronomical body part which is part of the planetary surface between the peak of an elevation or the bottom of a depression and relatively flat surrounding land.
MA:ma
The mixture of gases (roughly (by molar content/volume: 78% nitrogen, 20.95% oxygen, 0.93% argon, 0.038% carbon dioxide, trace amounts of other gases, and a variable amount (average around 1%) of water vapor) that surrounds the planet Earth.
EcoLexicon:air
LTER:18
SWEETRealm:Air
https://en.wikipedia.org/wiki/Air
envoPolar
air
The mixture of gases (roughly (by molar content/volume: 78% nitrogen, 20.95% oxygen, 0.93% argon, 0.038% carbon dioxide, trace amounts of other gases, and a variable amount (average around 1%) of water vapor) that surrounds the planet Earth.
https://en.wikipedia.org/wiki/Air
An environmental material primarily composed of dihydrogen oxide in its liquid form.
water
EcoLexicon:water
LTER:617
https://en.wikipedia.org/wiki/Water
liquid water
An environmental material primarily composed of dihydrogen oxide in its liquid form.
MA:ma
Sediment is an environmental substance comprised of any particulate matter that can be transported by fluid flow and which eventually is deposited as a layer of solid particles on the bedor bottom of a body of water or other liquid.
EcoLexicon:sediment
EcoLexicon:sedimentation
LTER:492
LTER:493
SWEETRealm:Sediment
https://en.wikipedia.org/wiki/Sediment
envoPolar
It is recommended to use a combination of sediment terms to describe a more specific sediment type.
sediment
Sediment is an environmental substance comprised of any particulate matter that can be transported by fluid flow and which eventually is deposited as a layer of solid particles on the bedor bottom of a body of water or other liquid.
https://en.wikipedia.org/wiki/Sediment
Minute solid particles with diameters less than 500 micrometers. Occurs in and may be deposited from, the atmosphere.
EcoLexicon:dust
SWEETRealm:Dust
https://en.wikipedia.org/wiki/Dust
envoPolar
dust
Minute solid particles with diameters less than 500 micrometers. Occurs in and may be deposited from, the atmosphere.
https://en.wikipedia.org/wiki/Dust
Water which contains a significant concentration of dissolved salts.
EcoLexicon:saltwater
SWEETRealm:SalineWater
SWEETRealm:SaltWater
https://en.wikipedia.org/wiki/Saline_water
salt water
The threshold salt concentration for classifying water as saline varies, but typically begins at about 1,000 to 3,000 parts salt per million parts water or 0.1–0.3% salt by weight.
saline water
Rock formed from molten magma.
EcoLexicon:igneous_rock
SWEETRealm:IgneousRock
https://en.wikipedia.org/wiki/Igneous_rock
ENVO
igneous rock
Rock formed from molten magma.
https://en.wikipedia.org/wiki/Rock_%28geology%29
An igneous rock that results from the crystallization of a magma below the surface of the Earth.
SWEETRealm:IntrusiveRock
https://en.wikipedia.org/wiki/Plutonic_rock
ENVO
intrusive rock
plutonic rock
An igneous rock that results from the crystallization of a magma below the surface of the Earth.
https://en.wikipedia.org/wiki/Plutonic_rock
An igneous rock that results from magma reaching the surface either as lava or fragmental ejecta.
EcoLexicon:volcanic_rock
SWEETRealm:VolcanicRock
https://en.wikipedia.org/wiki/Volcanic_rock
ENVO
Due to the general suggestion that volcanic rock simply comes from a volcanic process, it's not immediately clear whether this is interchangeable with igneous rock.
volcanic rock
An igneous rock that results from magma reaching the surface either as lava or fragmental ejecta.
https://en.wikipedia.org/wiki/Rock_%28geology%29
A rock formed by deposition of either clastic sediments, organic matter, or chemical precipitates (evaporites), followed by compaction of the particulate matter and cementation during diagenesis.
EcoLexicon:sedimentary_rock
SWEETRealm:SedimentaryRock
https://en.wikipedia.org/wiki/Sedimentary_rock
ENVO
sedimentary rock
A rock formed by deposition of either clastic sediments, organic matter, or chemical precipitates (evaporites), followed by compaction of the particulate matter and cementation during diagenesis.
https://en.wikipedia.org/wiki/Rock_%28geology%29
A rock formed by subjecting any rock type (including previously-formed metamorphic rock) to different temperature and pressure conditions than those in which the original rock was formed. These temperatures and pressures are always higher than those at the Earth's surface and must be sufficiently high so as to change the original minerals into other mineral types or else into other forms of the same minerals (e.g. by recrystallisation).
EcoLexicon:metamorphic_rock
SWEETRealm:MetamorphicRock
https://en.wikipedia.org/wiki/Metamorphic_rock
ENVO
metamorphic rock
A rock formed by subjecting any rock type (including previously-formed metamorphic rock) to different temperature and pressure conditions than those in which the original rock was formed. These temperatures and pressures are always higher than those at the Earth's surface and must be sufficiently high so as to change the original minerals into other mineral types or else into other forms of the same minerals (e.g. by recrystallisation).
https://en.wikipedia.org/wiki/Rock_%28geology%29
A biome which is determined by a water body and which has ecological climax communities adapted to life in or on water.
LTER:41
aquatic biome
Sediment that accumulates in the flat or very gently sloping areas of the deep ocean basin floor. The three main types of deep marine sediment, also known as pelagic sediment, are siliceous oozes, calcareous oozes, and red clays.
EcoLexicon:marine_sediment
EcoLexicon:marine_sedimentation
SWEETRealm:MarineSediment
https://en.wikipedia.org/wiki/Marine_sediment
deep marine sediments
ENVO
pelagic sediment {alternative name}
envoPolar
deep marine sediment
Sediment that accumulates in the flat or very gently sloping areas of the deep ocean basin floor. The three main types of deep marine sediment, also known as pelagic sediment, are siliceous oozes, calcareous oozes, and red clays.
https://en.wikipedia.org/wiki/Marine_sediment#_note-8
Sediment which has increased levels of one or more chemical compounds.
chemically enriched sediment
ENVO
sea sand
ENVO
beach sand
A clastic rock with a particle size of 4 to 64 millimeters based on the Krumbein phi scale of sedimentology.
EcoLexicon:pebble
SWEETRealm:Pebble
https://en.wikipedia.org/wiki/Pebble
ENVO
pebble
A clastic rock with a particle size of 4 to 64 millimeters based on the Krumbein phi scale of sedimentology.
https://en.wikipedia.org/wiki/Pebble
A rock or rock fragment with a particle size between 64 and 256 mm.
EcoLexicon:cobble
SWEETRealm:Cobble
cobble
A rock or rock fragment with a particle size between 64 and 256 mm.
https://en.wikipedia.org/wiki/Cobble
Water which has physicochemical properties that have been determined by the processes occuring in a sea or ocean.
When we have more classes representing the various processes which make seawater seawater, we can further axiomatise this class.
EcoLexicon:sea_water
LTER:701
SWEETRealm:SeaWater
https://en.wikipedia.org/wiki/Sea_water
ocean water
seawater
This definition refers to water that is actually in a sea or ocean. This water may have a wide range of salinity levels.
sea water
Coastal sea water is sea water that is adjacent to a coast.
coastal water
coastal ocean water
coastal oceanic water
coastal seawater
envoPolar
The limits of what qualifies as "adjacent to" vary greatly. This should be defined on a data level and is left intentionally fuzzy here. The label is "coastal sea water" rather than "coastal water" as some large lakes are often said to have coasts.
coastal sea water
https://en.wikipedia.org/wiki/Coal_mine
ENVO
coal mine
ENVO
sandy beach
coal mine waste
ENVO
coal refuse
coal mine waste material
A power plant is a building which contains one or more generators which convert mechanical energy into electrical energy through the relative motion between a magnetic field and a conductor. The energy source harnessed to turn the generator varies widely.
SWEETRealm:PowerPlant
https://en.wikipedia.org/wiki/Power_plant
generating plant
generating station
power station
powerhouse
ENVO
power plant
A power plant is a building which contains one or more generators which convert mechanical energy into electrical energy through the relative motion between a magnetic field and a conductor. The energy source harnessed to turn the generator varies widely.
https://en.wikipedia.org/wiki/Power_station
A material which is not the desired output of a process and which is typically the input of a process which removes it from its producer (e.g. a disposal process).
This seems more like a role than a material. Anything can be waste. Thus, a "waste" role or disposition will be created and this class can then be populated by inference: any environmental material which has [role,disposition] waste will be considered a waste material.
EcoLexicon:waste
SWEETRealm:Waste
https://en.wikipedia.org/wiki/Waste
ENVO
waste material
Industrial wastes are liquid, solid and gaseous wastes originating from the manufacture of specific products.
This will become a defined class, with subclasses added through inference based on material having a 'waste role' and being associated with industrial entities.
industrial waste
ENVO
industrial waste material
Industrial wastes are liquid, solid and gaseous wastes originating from the manufacture of specific products.
ISBN:978-92-1-161386-5
http://stats.oecd.org/glossary/detail.asp?ID=1340
A structural basin that is below sea level.
EcoLexicon:ocean_basin
https://en.wikipedia.org/wiki/Ocean_basin
envoPolar
This class is defined in its geological sense:
https://en.wikipedia.org/wiki/ Hydrologically, an oceanic basin may be anywhere on Earth that is covered by seawater, but geologically ocean basins are large geologic basins that are below sea level. Geologically, there are other undersea geomorphological features such as the continental shelves, the deep ocean trenches, and the undersea mountain ranges (for example, the mid-Atlantic ridge) which are not considered to be part of the ocean basins; while hydrologically, oceanic basins include the flanking continental shelves and shallow, epeiric seas.
ocean basin
A structural basin that is below sea level.
https://en.wikipedia.org/wiki/Ocean_basin
A group of hydrous aluminium phyllosilicate (phyllosilicates being a subgroup of silicate minerals) minerals (see clay minerals), that are typically less than 2 micrometres in diameter. Clay consists of a variety of phyllosilicate minerals rich in silicon and aluminium oxides and hydroxides which include variable amounts of structural water.
EcoLexicon:clay
SWEETRealm:Clay
https://en.wikipedia.org/wiki/Clay
clay
A group of hydrous aluminium phyllosilicate (phyllosilicates being a subgroup of silicate minerals) minerals (see clay minerals), that are typically less than 2 micrometres in diameter. Clay consists of a variety of phyllosilicate minerals rich in silicon and aluminium oxides and hydroxides which include variable amounts of structural water.
https://en.wikipedia.org/wiki/Clay
A material entity that has been processed by humans or their technology in any way, including intermediate products as well as final products.
manufactured good
manufactured product
A material entity that has been processed by humans or their technology in any way, including intermediate products as well as final products.
https://en.wikipedia.org/wiki/Manufactured_product
A portion of enriched soil is a portion of soil with elevated levels of some material entity.
ENVO
This could be demoted to an inferred class if issues with double inheritance arise.
enriched soil
An industrial building is a building within which goods are produced and, optionally, stored or within which services are rendered.
It's possible that this will become an inferred class in the future. The United Nations' International Standard Industrial Classification should be referred to when expanding this branch. ISIC can also be used to identify processes. See http://unstats.un.org/unsd/cr/registry/regcst.asp?Cl=27&Lg=1.
industrial building
An industrial building is a building within which goods are produced and, optionally, stored or within which services are rendered.
https://en.wikipedia.org/wiki/Industry
Soil which has little to no water content and in which minerals and other soluble chemical entities have either bonded or become adsorbed to sold particles due to insufficient water availability.
dry soil
ENVO
acid dune sand
ENVO
rocky sand
Sand which is part of a desert.
desert sand
A portion of environmental material is a fiat object part which forms the medium or part of the medium of an environmental system.
portion of environmental material
Everything under this parent must be a mass noun. All subclasses are to be understood as being composed primarily of the named entity, rather than restricted to that entity. For example, "ENVO:water" is to be understood as "environmental material composed primarly of some CHEBI:water". This class is currently being aligned to the Basic Formal Ontology. Following this alignment, its definition and the definitions of its subclasses will be revised.
environmental material
A portion of environmental material is a fiat object part which forms the medium or part of the medium of an environmental system.
DOI:10.1186/2041-1480-4-43
MA:ma
ORCID:0000-0002-4366-3088
URL:http://ontology.buffalo.edu/smith/articles/niches.html
A layer of some material entity which is adjacent to one or more of its external boundaries and directly interacts with its immediate surroundings.
EcoLexicon:surface
http://sweetontology.net/reprSpaceGeometry/Surface
https://en.wikipedia.org/wiki/Surface
This class is distinct from a geometric surface, which is two-dimensional. The idea of "uppermost" may be problematic. Further, the definition of layer (the superclass of surface in rev 133) references surface. This may be another issue. Perhaps this can be made into an inferred class using 'bounding layer of' some material entity, note that 'bounding layer' implies containment, which may not be valid here.
surface layer
A layer of some material entity which is adjacent to one or more of its external boundaries and directly interacts with its immediate surroundings.
URL:http://www.merriam-webster.com/dictionary/surface
Airborne solid particles (also called dust or particulate matter (PM)) or liquid droplets.
EcoLexicon:aerosol
SWEETRealm:Aerosol
envoAtmo
Should connect to PATO as "quality of an aerosol"
aerosol
Airborne solid particles (also called dust or particulate matter (PM)) or liquid droplets.
https://en.wikipedia.org/wiki/Aerosol
Anthropogenic material in or on which organisms may live.
ENVO
anthropogenic environmental material
Anthropogenic material in or on which organisms may live.
MA:ma
Silt is granular material of a size somewhere between sand and clay whose mineral origin is quartz and feldspar.
EcoLexicon:silt
SWEETRealm:Silt
https://en.wikipedia.org/wiki/Silt
https://en.wikipedia.org/wiki/ In the Udden-Wentworth scale (due to Krumbein), silt particles range between 0.0039 to 0.0625 mm, larger than clay but smaller than sand particles. ISO 14688 grades silts between 0.002 mm and 0.063 mm. In actuality, silt is chemically distinct from clay, and unlike clay, grains of silt are approximately the same size in all dimensions; furthermore, their size ranges overlap. Clays are formed from thin plate-shaped particles held together by electrostatic forces, so present a cohesion. According to the U.S. Department of Agriculture Soil Texture Classification system, the sand-silt distinction is made at the 0.05 mm particle size. The USDA system has been adopted by the Food and Agriculture Organization (FAO). In the Unified Soil Classification System (USCS) and the AASHTO Soil Classification system, the sand-silt distinction is made at the 0.075 mm particle size (i.e., material passing the #200 sieve). Silts and clays are distinguished mechanically by their plasticity.
silt
Silt is granular material of a size somewhere between sand and clay whose mineral origin is quartz and feldspar.
https://en.wikipedia.org/wiki/Silt
A naturally occurring granular material composed of finely divided rock and mineral particles.
EcoLexicon:sand
LTER:484
SWEETRealm:Sand
https://en.wikipedia.org/wiki/Sand
ENVO
sand
A naturally occurring granular material composed of finely divided rock and mineral particles.
https://en.wikipedia.org/wiki/Sand
Gravel is an environmental material which is composed of pieces of rock that are at least two millimeters (2mm) in its largest dimension and no more than 75 millimeters.
EcoLexicon:gravel
SWEETRealm:Gravel
https://en.wikipedia.org/wiki/Gravel
The logical def is a little off here - it should really suggest that a gravel is composed of many "pieces" of gravel.
gravel
Gravel is an environmental material which is composed of pieces of rock that are at least two millimeters (2mm) in its largest dimension and no more than 75 millimeters.
https://en.wikipedia.org/wiki/Gravel
The marine pelagic biome (pelagic meaning open sea) is that of the marine water column, from the surface to the greatest depths.
ORCID:0000-0002-4366-3088
2010-03-15T11:17:06Z
ENVO
envoPolar
marine pelagic biome
The marine pelagic biome (pelagic meaning open sea) is that of the marine water column, from the surface to the greatest depths.
ISBN:978-0-7506-3384-0
The marine benthic biome (benthic meaning 'bottom') encompasses the seafloor and includes such areas as shores, littoral or intertidal areas, marine coral reefs, and the deep seabed.
ORCID:0000-0002-4366-3088
2010-03-15T11:17:06Z
SPIRE:Benthic
envoPolar
marine benthic biome
The marine benthic biome (benthic meaning 'bottom') encompasses the seafloor and includes such areas as shores, littoral or intertidal areas, marine coral reefs, and the deep seabed.
ISBN:978-0-7506-3384-0
ORCID:0000-0002-4366-3088
The marine bathyal zone biome comprises regions of the marine benthic biome between approximately 200 m and 3000 m depth. This zone generally coincides with the continental slope.
ORCID:0000-0002-4366-3088
2010-03-15T11:18:40Z
marine bathyal zone biome
The marine bathyal zone biome comprises regions of the marine benthic biome between approximately 200 m and 3000 m depth. This zone generally coincides with the continental slope.
ISBN:978-0-444-82619-0
ORCID:0000-0002-4366-3088
The marine abyssal zone biome comprises regions of the marine benthic biome between approximately 2500 m and 6000 m depth. This zone generally coincides with the continental rise and the abyssal plain.
ORCID:0000-0002-4366-3088
2010-03-15T11:18:40Z
marine abyssal zone biome
The marine abyssal zone biome comprises regions of the marine benthic biome between approximately 2500 m and 6000 m depth. This zone generally coincides with the continental rise and the abyssal plain.
ISBN:978-0-444-82619-0
ORCID:0000-0002-4366-3088
The marine hadal zone biome describes sea floor deeper than 6000 m such as that of the oceanic trenches.
ORCID:0000-0002-4366-3088
2010-03-15T11:18:40Z
marine hadal zone biome
The marine hadal zone biome describes sea floor deeper than 6000 m such as that of the oceanic trenches.
ISBN:978-0-444-82619-0
ORCID:0000-0002-4366-3088
A biome expressed by strips or ridges of rocks, sand, or coral that rises to or near the surface of a body of marine water.
ORCID:0000-0002-4366-3088
2010-03-15T11:18:40Z
ENVO
marine reef biome
A biome expressed by strips or ridges of rocks, sand, or coral that rises to or near the surface of a body of marine water.
ISBN:978-0-618-45504-1
ORCID:0000-0002-4366-3088
The neritic epipelagic zone biome comprises the marine water column above a continental shelf.
ORCID:0000-0002-4366-3088
2010-03-15T11:19:19Z
ENVO
neritic pelagic zone biome
The neritic epipelagic zone biome comprises the marine water column above a continental shelf.
ISBN:978-0-444-82619-0
ISBN:978-0-7506-3384-0
ORCID:0000-0002-4366-3088
The oceanic epipelagic zone biome comprises the marine water column offshore, beyond a continental shelf.
ORCID:0000-0002-4366-3088
2010-03-15T11:19:19Z
ENVO
oceanic pelagic zone biome
The oceanic epipelagic zone biome comprises the marine water column offshore, beyond a continental shelf.
ISBN:978-0-444-82619-0
ISBN:978-0-7506-3384-0
ORCID:0000-0002-4366-3088
The oceanic sea surface microlayer (SML) biome comprises the top 1000 micrometers of the marine surface waters occurring offshore, away from a continental shelf. It is the boundary layer where all exchange occurs between the atmosphere and the ocean. The chemical, physical, and biological properties of the SML differ greatly from the sub-surface water just a few centimeters beneath.
ORCID:0000-0002-4366-3088
2010-03-15T11:21:03Z
ENVO
oceanic sea surface microlayer biome
The oceanic sea surface microlayer (SML) biome comprises the top 1000 micrometers of the marine surface waters occurring offshore, away from a continental shelf. It is the boundary layer where all exchange occurs between the atmosphere and the ocean. The chemical, physical, and biological properties of the SML differ greatly from the sub-surface water just a few centimeters beneath.
ORCID:0000-0002-4366-3088
https://en.wikipedia.org/wiki/Sea_surface_microlayer
The neritic sea surface microlayer (SML) biome comprises the top 1000 micrometers of marine surface waters occurring above a continental shelf. It is the boundary layer where all exchange occurs between the atmosphere and the ocean. The chemical, physical, and biological properties of the SML differ greatly from the sub-surface water just a few centimeters beneath.
ORCID:0000-0002-4366-3088
2010-03-15T11:22:09Z
ENVO
neritic sea surface microlayer biome
The neritic sea surface microlayer (SML) biome comprises the top 1000 micrometers of marine surface waters occurring above a continental shelf. It is the boundary layer where all exchange occurs between the atmosphere and the ocean. The chemical, physical, and biological properties of the SML differ greatly from the sub-surface water just a few centimeters beneath.
ORCID:0000-0002-4366-3088
https://en.wikipedia.org/wiki/Sea_surface_microlayer
A prominent or distinctive aspect, quality, or characteristic of environments occurring within the marine water column.
ORCID:0000-0002-4366-3088
2010-03-16T12:10:50Z
envoPolar
marine pelagic feature
A prominent or distinctive aspect, quality, or characteristic of environments occurring within the marine water column.
ISBN:978-0-618-45504-1
ORCID:0000-0002-4366-3088
A marine biome which is determined by an ocean.
ORCID:0000-0002-4366-3088
2010-03-15T11:23:23Z
envoPolar
Ocean biomes are determined by major bodies of saline water, principal components of the hydrosphere. Approximately 71% of the Earth's surface is covered by ocean, a continuous body of water that is customarily divided into several principal oceans and smaller seas. More than half of this area is over 3,000 metres (9,800 ft) deep. Average oceanic salinity is around 35 parts per thousand (ppt) (3.5%), and nearly all seawater has a salinity in the range of 30 to 38 ppt.
ocean biome
A marine biome which is determined by an ocean.
ORCID:0000-0002-4366-3088
https://en.wikipedia.org/wiki/Ocean
The marine coral reef biome comprises constructional wave-resistant entities which are primarily built by corals and are often cemented together. The growth of these structures is aided by zooxanthellae, algae that are symbiotic with the reef-building corals.
ORCID:0000-0002-4366-3088
2010-03-15T11:27:06Z
ENVO
marine coral reef biome
The marine coral reef biome comprises constructional wave-resistant entities which are primarily built by corals and are often cemented together. The growth of these structures is aided by zooxanthellae, algae that are symbiotic with the reef-building corals.
ISBN:978-0-7506-3384-0
ORCID:0000-0002-4366-3088
Particulate material is an environmental material which is composed of microscopic portions of solid or liquid material suspended in another environmental material.
Subclasses should be assigned by inference.
envoAtmo
envoPolar
particulate matter
A prominent or distinctive aspect, quality, or characteristic of environments occurring on or along marine benthic environments.
ORCID:0000-0002-4366-3088
2010-03-16T12:27:00Z
marine benthic feature
A prominent or distinctive aspect, quality, or characteristic of environments occurring on or along marine benthic environments.
ISBN:978-0-618-45504-1
ORCID:0000-0002-4366-3088
ORCID:0000-0002-4366-3088
2010-03-20T06:43:45Z
ENVO
marine reef
Environmental material derived from living organisms and composed primarily of one or more biomacromolecules.
ORCID:0000-0002-4366-3088
2010-03-20T08:40:04Z
EcoLexicon:organic_material
biomass
organic material
Environmental material derived from living organisms and composed primarily of one or more biomacromolecules.
ISBN:978-0-618-45504-1
ORCID:0000-0002-4366-3088
A shrubland biome is a terrestrial biome which includes, across its entire spatial extent, dense groups of shrubs.
ORCID:0000-0002-4366-3088
2013-04-07T14:26:46Z
Preliminary definition.
shrubland biome
A desert biome is a terrestrial biome which loses more liquid water by evapotranspiration than is supplied by precipitation and includes communities adapted to these conditions.
ORCID:0000-0002-4366-3088
2013-04-07T14:26:46Z
SPIRE:Desert_or_dune
wwfBiome
Preliminary definition.
desert biome
A terrestrial biome which comprises a tundra ecosystem that has reached its climax community.
ORCID:0000-0002-4366-3088
2013-04-07T14:26:46Z
SPIRE:Tundra
envoPolar
wwfBiome
Preliminary definition.
tundra biome
An environmental condition is a range of a determinate quality or combination of qualities that are present in an environmental system.
ORCID:0000-0002-4366-3088
2013-04-07T14:35:18Z
envoPolar
A condition defines a restricted range of a given quality or combination of qualities. If an environment class, E, has_condition C, then all qualities listed in C are restricted to the ranges defined in C in E. This is not intended as a logical conditional.
environmental condition
An environmental condition is a range of a determinate quality or combination of qualities that are present in an environmental system.
DOI:10.1186/2041-1480-4-43
A tropical condition is an environmental condition in which an environmental system receives high yearly solar irradiance per unit area and, on Earth, the Sun reaches a subsolar point at least once during the solar year. This results in a hot and moist year-round climate at low elevations, which have a monthly average temperature above 18 degrees Celsius.
ORCID:0000-0002-4366-3088
2013-04-07T14:36:47Z
EcoLexicon:the_tropics
SPIRE:Tropical
tropical
A tropical condition is an environmental condition in which an environmental system receives high yearly solar irradiance per unit area and, on Earth, the Sun reaches a subsolar point at least once during the solar year. This results in a hot and moist year-round climate at low elevations, which have a monthly average temperature above 18 degrees Celsius.
https://en.wikipedia.org/wiki/Tropical
A temperate condition is an environmental condition in which an environmental system receives less solar irradiance than those with subpolar conditions, but greater than those with subtropical conditions.
ORCID:0000-0002-4366-3088
2013-04-07T14:36:47Z
SPIRE:Temperate
tepid climate
This class' definition is less satisfactory than the other latitudinal conditoins.
temperate
A temperate condition is an environmental condition in which an environmental system receives less solar irradiance than those with subpolar conditions, but greater than those with subtropical conditions.
https://en.wikipedia.org/wiki/Temperate_climate
tepid climate
https://en.wikipedia.org/wiki/Temperate_climate
A montane shrubland biome is a shrubland biome which occurs in regions elevated above sea level and which has community structure determined by elevation-dependent environmental conditions.
ORCID:0000-0002-4366-3088
2013-04-07T14:40:32Z
wwfBiome
Preliminary definition.
montane shrubland biome
An anthropogenic terrestrial biome is a terrestrial biome which has community structures determined by human activity.
ORCID:0000-0002-4366-3088
2013-04-07T14:45:22Z
anthrome
human biome
Preliminary definition.
anthropogenic terrestrial biome
An anthropogenic terrestrial biome is a terrestrial biome which has community structures determined by human activity.
http://www.eoearth.org/view/article/150128/
An environmental condition in which annual precipitation is less than half of annual potential evapotranspiration.
ORCID:0000-0002-4366-3088
2013-04-24T13:28:18Z
EcoLexicon:aridity
envoPolar
arid
Lava is a mixture of molten or semi-molten rock, volatiles, and solids which has extruded beyond a planetary crust.
PLB
2013-05-05T16:52:47Z
EcoLexicon:lava
SWEETRealm:Lava
ENVO
Some use 'lava' to refer to rock that is formed when lava cools. This is not the intended meaning of this class. See 'igneous rock' or similar.
lava
Lava is a mixture of molten or semi-molten rock, volatiles, and solids which has extruded beyond a planetary crust.
https://en.wikipedia.org/wiki/Lava
A polar condition is an environmental condition in which an environmental system receives low, yearly solar irradiance per unit area, resulting in colder climatic conditions.
ORCID:0000-0002-4366-3088
2013-05-08T07:49:36Z
SPIRE:Polar
SWEETRealm:Polarization
frigid
envoPolar
On Earth, polar conditions are such that every month has average temperature lower than 10 degrees Celsius. Note that this class refers to a climatic rather than a positional condition.
polar
A polar condition is an environmental condition in which an environmental system receives low, yearly solar irradiance per unit area, resulting in colder climatic conditions.
https://en.wikipedia.org/wiki/Polar_climate
frigid
https://en.wikipedia.org/wiki/Polar_climate
A system which has the disposition to environ one or more material entities.
2013-09-23T16:04:08Z
EcoLexicon:environment
environment
In ENVO's alignment with the Basic Formal Ontology, this class is being considered as a subclass of a proposed BFO class "system". The relation "environed_by" is also under development. Roughly, a system which includes a material entity (at least partially) within its site and causally influences that entity may be considered to environ it. Following the completion of this alignment, this class' definition and the definitions of its subclasses will be revised.
environmental system
A system which has the disposition to environ one or more material entities.
DOI:10.1186/2041-1480-4-43
A mineral material is an environmental material which is primarily composed of some substance that is naturally occurring, solid and stable at room temperature, representable by a chemical formula, usually abiogenic, and that has an ordered atomic structure.
Look for "mineral" in a chemical or geochemical ontology to formalise the composed primarily of link.
From https://en.wikipedia.org/wiki/ [A mineral] is different from a rock, which can be an aggregate of minerals or non-minerals and does not have a specific chemical composition. The exact definition of a mineral is under debate, especially with respect to the requirement a valid species be abiogenic, and to a lesser extent with regards to it having an ordered atomic structure.
ORCID:0000-0002-4366-3088
2013-10-05T12:37:41Z
LTER:341
mineral material
A mineral material is an environmental material which is primarily composed of some substance that is naturally occurring, solid and stable at room temperature, representable by a chemical formula, usually abiogenic, and that has an ordered atomic structure.
https://en.wikipedia.org/wiki/Mineral
Water vapour is a vapour which is the gas phase of water.
ORCID:0000-0002-4366-3088
2013-10-10T07:58:18Z
aqueous vapor
aqueous vapour
water vapor
ENVO
Perhaps a better relation between water vapour and water can be found in or added to RO?
water vapour
Water vapour is a vapour which is the gas phase of water.
https://en.wikipedia.org/wiki/Water_vapor
aqueous vapor
https://en.wikipedia.org/wiki/Water_vapor
aqueous vapour
https://en.wikipedia.org/wiki/Water_vapor
water vapor
https://en.wikipedia.org/wiki/Water_vapor
An atmosphere is a layer of gases surrounding a material body of sufficient mass that is held in place by the gravity of the body.
ORCID:0000-0002-4366-3088
2013-10-10T08:14:50Z
LTER:48
atmosphere
An atmosphere is a layer of gases surrounding a material body of sufficient mass that is held in place by the gravity of the body.
https://en.wikipedia.org/wiki/Atmosphere
https://en.wikipedia.org/wiki/Physical_geography
Atmospheric water vapour is water vapour that is part of an atmosphere.
ORCID:0000-0002-4366-3088
2013-10-10T08:22:07Z
atmospheric water vapor
ENVO
envoPolar
atmospheric water vapour
Atmospheric water vapour is water vapour that is part of an atmosphere.
https://en.wikipedia.org/wiki/Water_vapor
atmospheric water vapor
https://en.wikipedia.org/wiki/Water_vapor
A structural basin is a geological depression formed by tectonic warping of previously flat lying rock strata.
ORCID:0000-0002-4366-3088
2013-10-12T16:30:32Z
structural basin
A structural basin is a geological depression formed by tectonic warping of previously flat lying rock strata.
https://en.wikipedia.org/wiki/Structural_basin
A large unit of land or water containing a geographically distinct assemblage of species, natural communities, and environmental conditions.
ORCID:0000-0002-4366-3088
2013-10-12T17:21:09Z
envoPolar
Unlike biomes, ecoregions are geographically defined entities. ENVO's sister project, GAZ, contains terms for instances of ecoregions (e.g. Beringia lowland tundra). Requests for new terms should be directed to GAZ. ENVO will only contain this top-level class. The class' definition is preliminary and will be aligned to BFO.
ecoregion
A large unit of land or water containing a geographically distinct assemblage of species, natural communities, and environmental conditions.
DOI:10.1641/0006-3568(2001)051[0933:TEOTWA]2.0.CO;2
URL:http://worldwildlife.org/biomes
Ice is water frozen into a solid state. It can appear transparent or opaque bluish-white color, depending on the presence of impurities or air inclusions. The addition of other materials such as soil may further alter its appearance.
ORCID:0000-0002-4366-3088
2013-10-13T12:01:28Z
LTER:262
ice
envoPolar
water ice
Ice is water frozen into a solid state. It can appear transparent or opaque bluish-white color, depending on the presence of impurities or air inclusions. The addition of other materials such as soil may further alter its appearance.
https://en.wikipedia.org/wiki/Ice
ice
http://www.eionet.europa.eu/gemet/concept/4131
Ecozones delineate large areas of a planetary surface within which organisms have been evolving in relative isolation over long periods of time, separated from one another by geographic features, such as oceans, broad deserts, or high mountain ranges, that constitute barriers to migration.
ORCID:0000-0002-4366-3088
2013-10-13T18:32:46Z
envoPolar
ENVO contains this top-level class, but all instances will be in GAZ. The definition is preliminary and will be aligned to BFO.
https://en.wikipedia.org/wiki/ Ecozones correspond to the floristic kingdoms of botany or zoogeographic regions of zoology. Ecozones are characterized by the evolutionary history of the organisms they contain. They are distinct from biomes, also known as major habitat types, which are divisions of the Earth's surface based on life form, or the adaptation of plants and animals to climatic, soil, and other conditions. Biomes are characterized by similar climax vegetation. Each ecozone may include a number of different biomes. A tropical moist broadleaf forest in Central America, for example, may be similar to one in New Guinea in its vegetation type and structure, climate, soils, etc., but these forests are inhabited by plants and animals with very different evolutionary histories.
ecozone
Ecozones delineate large areas of a planetary surface within which organisms have been evolving in relative isolation over long periods of time, separated from one another by geographic features, such as oceans, broad deserts, or high mountain ranges, that constitute barriers to migration.
https://en.wikipedia.org/wiki/ecozone
A layer is a quantity of some material which is spatially continuous, has comparable thickness, and usually covers some surface.
ORCID:0000-0002-4366-3088
2013-10-15T16:42:02Z
envoPolar
Preliminary definition.
layer
A layer is a quantity of some material which is spatially continuous, has comparable thickness, and usually covers some surface.
Wiktionary:layer
A layer which is part of a lake.
ORCID:0000-0002-4366-3088
2013-10-15T16:57:43Z
ENVO
envoPolar
Note that this class does not contain metalimnion as a subclass. The metaliminon is classified as a thermocline.
lake layer
A mass of water ice.
Class should be populated by inference and asserted subclasses redistributed.
ORCID:0000-0002-4366-3088
2013-10-15T19:49:11Z
accumulation of ice
ice accumulation
http://sweetontology.net/phenCryo/Accumulation
envoPolar
ice mass
A layer that is part of a marine water body.
ORCID:0000-0002-4366-3088
envoMarine
envoPolar
marine layer
A layer that is part of a marine water body.
ORCID:0000-0002-4366-3088
An endolithic environment is an environment that exists within solid rock.
endolithic environment
An environmental system which has its properties and dynamics determined by saline water.
Water (saline)
envoEmpo
envoOmics
envoPolar
saline water environment
Water (saline)
http://press.igsb.anl.gov/earthmicrobiome/protocols-and-standards/emp-ontology-empo/
An environment which has a lower temperature than some local or global average.
envoPolar
The definition of the deprecated 'cold temperature habitat' class, which this class was derived from, quotes an upper threshold of 15 degrees Celsius for 'coldness'.
cold environment
An anthropogenic environment is an environmental system which is the product of human activity.
Unsatisfactory definition here. Must consider the threshold that makes an environmental system anthropogenic.
anthropogenic environment
An environment whose dynamics are strongly influenced by water.
aquatic environment
A rocky slope is a slope which has a surface primarily composed of rock.
rocky slope
A marine environment and enviroment which is determined by a marine water body.
envoPolar
marine environment
A marine environment and enviroment which is determined by a marine water body.
NM:nm
An environmental system determined by seawater.
ocean water environment
envoPolar
sea water environment
The atmospheric boundary layer is the lowest layer of an atmosphere which is strongly influenced by its contact with a planetary surface with strong vertical mixing and in which physical quantities such as flow velocity, temperature, and moisture display rapid fluctuations (turbulence).
planetary boundary layer
envoPolar
atmospheric boundary layer
A planetary surface is a surface layer where the solid or liquid material of a planet comes into contact with an atmosphere or outer space.
a useful class: this can be used to define sub-terrestrial and sub-marine entities
planetary surface
A layer in a water mass, itself composed primarily of water.
envoPolar
This class will eventually be populated by inference, and its asserted subclasses removed.
aquatic layer
A gravelly slope is a slope which has a surface primarily composed of gravel.
gravelly slope
A hillside is a slope that is part of a hill.
brae
hillside
A talus slope is a slope which has a surface layer composed of scree.
scree slope
talus slope
A biome which is subject to polar climatic conditions.
envoPolar
This class is primarily for inference and, in general, should not be used directly by annotators. If you're an annotator, please consider using a more informative term such as 'tundra biome'.
polar biome
An altitudinal condition which inheres in a bearer by virtue of the bearer being located at an altitude between mid-altitude forests and the tree line.
ORCID:0000-0002-4366-3088
LTER:350
envoPolar
The exact level of the tree line varies with local climate, but typically the tree line is found where mean monthly soil temperatures never exceed 10.0 degrees C and the mean annual soil temperatures are around 6.7 degrees C. In the tropics, this region is typified by montane rain forest (above 3,000 ft) while at higher latitudes coniferous forests often dominate.
montane
An altitudinal condition which inheres in a bearer by virtue of the bearer being located at an altitude between mid-altitude forests and the tree line.
https://en.wikipedia.org/wiki/Altitudinal_zonation
The exact level of the tree line varies with local climate, but typically the tree line is found where mean monthly soil temperatures never exceed 10.0 degrees C and the mean annual soil temperatures are around 6.7 degrees C. In the tropics, this region is typified by montane rain forest (above 3,000 ft) while at higher latitudes coniferous forests often dominate.
https://en.wikipedia.org/wiki/Altitudinal_zonation
An altitudinal condition is an environmental condition in which ranges of factors such as temperature, humidity, soil composition, solar irradiation, and tree density vary with ranges in altitude.
ORCID:0000-0002-4366-3088
envoPolar
Depending on the latitude (and, to a lesser extent, other factors), the actual location of the zones where these conditions are in effect will change.
altitudinal condition
An altitudinal condition is an environmental condition in which ranges of factors such as temperature, humidity, soil composition, solar irradiation, and tree density vary with ranges in altitude.
https://en.wikipedia.org/wiki/Altitudinal_zonation
A portion of acidic water is a portion of water with a pH less than 7.
acidic water
An tundra climatic condition is a polar condition in which at least one month's average temperature exceeds 0 degrees Celsius.
envoPolar
tundra climatic condition
An tundra climatic condition is a polar condition in which at least one month's average temperature exceeds 0 degrees Celsius.
https://en.wikipedia.org/wiki/Polar_climate
Snow is an environmental material which is primarily composed of flakes of crystalline water ice.
envoPolar
snow
Snow is an environmental material which is primarily composed of flakes of crystalline water ice.
http://www.eionet.europa.eu/gemet/concept/7769
https://en.wikipedia.org/wiki/Snow
A site which has its extent determined by the presence or influence of one or more components of an environmental system or the processes occurring therein.
environmental area
envoPolar
Formerly, this class was an experimental class and a subclass of "environmental feature". It is now aligned to BFO. The class was not obsoleted as the core semantics maintained their stability through its transition.
environmental zone
A building part is a construction which is part of a building.
Not recommended for annotation. This class is likely to be made into an inferred class as its subclasses are distributed among more meaningful superclasses (i.e. ceiling is_a surface layer). See for example, "building floor". The boundaries between building parts may be bona fide or fiat.
building part
A disposition which is realised by an environmental system or system parts thereof.
ORCID:0000-0002-4366-3088
This class and its subclasses are experimental and are being developed with NCEAS use cases in mind.
environmental disposition
A layer that is part of the atmosphere.
ORCID:0000-0002-4366-3088
atmospheric layering
envoPolar
This could be made into an inferred class, rather than having asserted subclasses.
atmospheric layer
atmospheric layering
GEMET:http://www.eionet.europa.eu/gemet/concept/627
A boundary layer is a layer of fluid in the immediate vicinity of a bounding surface where the effects of viscosity are significant enough to distort the surrounding non-viscous flow.
ORCID:0000-0002-4366-3088
boundary layer
boundary layer
A boundary layer is a layer of fluid in the immediate vicinity of a bounding surface where the effects of viscosity are significant enough to distort the surrounding non-viscous flow.
https://en.wikipedia.org/wiki/Boundary_layer
boundary layer
http://www.eionet.europa.eu/gemet/concept/976
A lentic water body is a water body in which the accumulated water, in its totality, has very little to no directed flow.
lentic water body
Hydrological condensation is a process in which atmospheric water vapour undergoes a phase transition from the gas phase to the liquid phase.
condensation
envoAtmo
envoPolar
"process" is included in the label to make it clear that we are not referring to the condensed material (e.g. water droplets, window fog)
hydrological condensation process
Hydrological condensation is a process in which atmospheric water vapour undergoes a phase transition from the gas phase to the liquid phase.
https://en.wikipedia.org/wiki/Condensation
The long-term fluctuations in temperature, precipitation, wind, and all other aspects of the Earth's climate. External processes, such as solar-irradiance variations, variations of the Earth's orbital parameters (eccentricity, precession, and inclination), lithosphere motions, and volcanic activity, are factors in climatic variation. Internal variations of the climate system, e.g., changes in the abundance of greenhouse gases, also may produce fluctuations of sufficient magnitude and variability to explain observed climate change through the feedback processes interrelating the components of the climate system.
envoPolar
Definition vebatim from GEMET. Will need to be refined. Further, distinction between "climate change" and (one or many) "climate change process" will need to be discussed. Fluctuations are not processes, per se.
climate change
The long-term fluctuations in temperature, precipitation, wind, and all other aspects of the Earth's climate. External processes, such as solar-irradiance variations, variations of the Earth's orbital parameters (eccentricity, precession, and inclination), lithosphere motions, and volcanic activity, are factors in climatic variation. Internal variations of the climate system, e.g., changes in the abundance of greenhouse gases, also may produce fluctuations of sufficient magnitude and variability to explain observed climate change through the feedback processes interrelating the components of the climate system.
GEMET:http://www.eionet.europa.eu/gemet/concept/1471
A volcanic eruption is a process during which lava, tephra (ash, lapilli, volcanic bombs and blocks), and assorted gases are expelled from a volcanic vent or fissure.
environmental_hazards
volcanic eruption
A volcanic eruption is a process during which lava, tephra (ash, lapilli, volcanic bombs and blocks), and assorted gases are expelled from a volcanic vent or fissure.
https://en.wikipedia.org/wiki/Types_of_volcanic_eruptions
A landmass which is part of a planet.
land
ground
planetary landmass
A landmass which is part of a planet.
Adpated from https://en.wikipedia.org/wiki/Planetary_surface
Outer space is a hard vacuum containing a low density of particles, predominantly a plasma of hydrogen and helium as well as electromagnetic radiation, magnetic fields, neutrinos, dust and cosmic rays that exists between celestial bodies.
space
envoAstro
outer space
Outer space is a hard vacuum containing a low density of particles, predominantly a plasma of hydrogen and helium as well as electromagnetic radiation, magnetic fields, neutrinos, dust and cosmic rays that exists between celestial bodies.
https://en.wikipedia.org/wiki/Outer_space
A planetary crust is the outermost solid shell of a rocky planet or natural satellite, which is chemically distinct from the underlying mantle.
crust
This class is meant to be applicable accross planets. Earth's crust would be an instance.
planetary crust
A planetary crust is the outermost solid shell of a rocky planet or natural satellite, which is chemically distinct from the underlying mantle.
https://en.wikipedia.org/wiki/Crust_(geology)
A planetary structural layer is laminar part of a terrestrial planet or other rocky body large enough to have differentiation by density. Planetary layers have differing physicochemical properties and composition.
Label should be improved to match definition.
planetary structural layer
A planetary mantle is a planetary layer which is an interior part of a terrestrial planet or other rocky body large enough to have differentiation by density.
mantle
This class is meant to be applicable accross planets. Earth's mantle would be an instance.
planetary mantle
A planetary mantle is a planetary layer which is an interior part of a terrestrial planet or other rocky body large enough to have differentiation by density.
https://en.wikipedia.org/wiki/Mantle_(geology)
A lithosphere is the outermost shell of a terrestrial-type planet or natural satellite that is defined by its rigid mechanical properties.
Earth's lithosphere includes the crust and uppermost mantle.
lithosphere
A lithosphere is the outermost shell of a terrestrial-type planet or natural satellite that is defined by its rigid mechanical properties.
https://en.wikipedia.org/wiki/Lithosphere
Magma is a mixture of molten or semi-molten rock, volatiles, and solids that is found beneath the uppermost solid layer of a planetary body. Besides molten rock, magma may also contain suspended crystals, dissolved gas and sometimes gas bubbles.
magma
Magma is a mixture of molten or semi-molten rock, volatiles, and solids that is found beneath the uppermost solid layer of a planetary body. Besides molten rock, magma may also contain suspended crystals, dissolved gas and sometimes gas bubbles.
https://en.wikipedia.org/wiki/Magma
An explosive eruption is a volcanic process in which pressurised magma is violently expelled and froths into volcanic ash. Explosive eruptions can eject a cloud of rocks, dust, gas, and pyroclastic material which may then collapse, creating a pyroclastic flow of hot volcanic matter.
environmental_hazards
explosive eruption
An explosive eruption is a volcanic process in which pressurised magma is violently expelled and froths into volcanic ash. Explosive eruptions can eject a cloud of rocks, dust, gas, and pyroclastic material which may then collapse, creating a pyroclastic flow of hot volcanic matter.
https://en.wikipedia.org/wiki/Explosive_eruption
A settlement with a high density of buildings and inhabitants.
See also: http://www.ecotope.org/anthromes/v1/guide/urban/12_dense_settlements/default.aspx
The thresholds for what makes a settlment "dense" can be determined as needed. If there is a specific threshold that should be added to ENVO, please make a new class request.
dense settlement
Tephra is fragmental material produced by a volcanic eruption regardless of composition, fragment size or emplacement mechanism.
tephra
Tephra is fragmental material produced by a volcanic eruption regardless of composition, fragment size or emplacement mechanism.
https://en.wikipedia.org/wiki/Tephra
A role that is realized in some process wherein the bearer is discarded or not utilized further.
This definition is preliminary.
waste role
A geological fracture is any separation in a geologic formation, such as a joint or a fault that divides a mass of rock into two or more pieces.
fracture
SWEETRealm:Fissure
fissure
geological fracture
A geological fracture is any separation in a geologic formation, such as a joint or a fault that divides a mass of rock into two or more pieces.
https://en.wikipedia.org/wiki/Fracture_(geology)
fissure
Genomes:fissure
A mass of water.
water mass
A coast is the area where land meets the sea, ocean, or lake.
Used for both marine and lake coasts. The boundary of the coast is fuzzy and it overlaps both the water body and land in quesiton. Compared to 'shore'
coast
A coast is the area where land meets the sea, ocean, or lake.
https://en.wikipedia.org/wiki/Coast
A tsunami is a process during which a series of waves is generated in a water body, typically an ocean or large lake, by the displacement of a large volume of water. Earthquakes, volcanic eruptions and other underwater explosions (including detonations of underwater nuclear devices), landslides, glacier calvings, meteorite impacts and other disturbances above or below water all have the potential to generate a tsunami.
seismic sea wave
tidal wave
environmental_hazards
tsunami
A tsunami is a process during which a series of waves is generated in a water body, typically an ocean or large lake, by the displacement of a large volume of water. Earthquakes, volcanic eruptions and other underwater explosions (including detonations of underwater nuclear devices), landslides, glacier calvings, meteorite impacts and other disturbances above or below water all have the potential to generate a tsunami.
https://en.wikipedia.org/wiki/Tsunami
Hydrological precipitation is a process during which any product of the condensation of atmospheric water vapour is pulled to the planetary surface by gravity.
precipitation
"process" is included in the label to make it clear that we are not referring to the precipitated material (e.g. snow, rain, sleet)
hydrological precipitation process
Hydrological precipitation is a process during which any product of the condensation of atmospheric water vapour is pulled to the planetary surface by gravity.
https://en.wikipedia.org/wiki/Precipitation
A meteotsunami is a tsunami caused by atmospheric processes and differences in air pressure.
Ambiguity as to whether this label refers to the process or the material entities (the waves). The material entities are a type of severe storm surge.
rissaga
environmental_hazards
meteotsunami
A meteotsunami is a tsunami caused by atmospheric processes and differences in air pressure.
https://en.wikipedia.org/wiki/Meteotsunami
rissaga
Language: Catalan
Condensation is a process during which a gas undergoes a phase transition into a liquid.
condensation process
Condensation is a process during which a gas undergoes a phase transition into a liquid.
https://en.wikipedia.org/wiki/Condensation
An environmental system which can sustain and allow the growth of an ecological population.
EcoLexicon:habitat
LTER:238
SWEETRealm:Habitat
https://en.wikipedia.org/wiki/Habitat
A habitat's specificity to an ecological population differentiates it from other environment classes.
habitat
An environmental system which can sustain and allow the growth of an ecological population.
EnvO:EnvO
A process in which natural ecosystems present over an expanse of land are removed and replaced with anthropogenic ecosystems.
An SDGIO request. Likely to be refined and revised. This looks like an aggregate class, subsuming a range of processes which can lead to degradation.
These anthropogenic ecosystems may include urban or other built-up settlements or anthropogenic ecosystems used for activities such as forestry or agriculture.
land consumption process
A process in which natural ecosystems present over an expanse of land are removed and replaced with anthropogenic ecosystems.
Adapted from EEA (1997) The concept of environmental space, Copenhagen, URL: http://www.eea.europa.eu/publications/92-9167-078-2/at_download/file
An area of a planet's surface which is primarily composed of bedrock, desert pavement, scarp rock, talus, material exposed by slides, volcanic material, glacial debris, sand, material exposed during strip mining, gravel, and other accumulations of earthen material in contact with an atmospheric column extending from the planetary boundary layer to the planet's exosphere with little to no physical obstruction.
The range of entities that are considered "barren land" are not exhaustive, making axiomatisation risky at this stage.
Barren Land (Rock/Sand/Clay)
NLCD:31
envoPolar
nlcd2011
According to the NLCD 2011, areas of barren land generally have less than 15% cover of vegetation. A specific threshold is not asserted in this definition.
area of barren land
An area of a planet's surface which is primarily composed of bedrock, desert pavement, scarp rock, talus, material exposed by slides, volcanic material, glacial debris, sand, material exposed during strip mining, gravel, and other accumulations of earthen material in contact with an atmospheric column extending from the planetary boundary layer to the planet's exosphere with little to no physical obstruction.
https://en.wikipedia.org/wiki/Exosphere
https://en.wikipedia.org/wiki/Planetary_surface
https://www.mrlc.gov/nlcd11_leg.php
A part of an astronomical body which is primarily composed of a continuous volume of gaseous or aerosolised material held in shape by one or more environmental processes.
This may not need to be in the atmosphere, also note that "meteor" will do much of the same work.
envoAtmo
Similar, in spirit, to landform. This class may need to be split into aerosols and 'pure' volumes of gas.
aeroform
A planned process during which a portion of environmental material is removed from a material entity.
This should be an OBI planned process. Pending import.
Created for SDGIO and intended to be a more general form of resource extraction process.
material extraction process
A process whereby a large volume of gas moves due to a disequilibrium of physical forces.
wind
envoAtmo
envoPolar
This class refers to all forms of "wind": from the familiar movement of air in the Earth's atmosphere to the solar wind. Use a subclass to be more precise.
mass gaseous flow
A process whereby a large volume of gas moves due to a disequilibrium of physical forces.
https://en.wikipedia.org/wiki/Wind
wind
A mass gaseous flow which occurrs in a planet's atmosphere due to internal pressure disequilibria.
envoAtmo
envoPolar
atmospheric wind
A mass gaseous flow which occurrs in a planet's atmosphere due to internal pressure disequilibria.
https://en.wikipedia.org/wiki/Wind
A material entity which is composed of one or more chemical entities and has neither independent shape nor volume but tends to expand indefinitely.
This class is to be populated by inference.
gas
gaseous environmental material
A material entity which is composed of one or more chemical entities and has neither independent shape nor volume but tends to expand indefinitely.
http://www.merriam-webster.com/dictionary/gas
A material entity which is composed of a volume of unbound positive and negative particles in roughly equal numbers, conducts electricity, and possesses internal magnetic fields.
An NTR for `quality of a plasma` has been posted on the PATO tracker: https://github.com/pato-ontology/pato/issues/88
plasma
A material entity which is composed of a volume of unbound positive and negative particles in roughly equal numbers, conducts electricity, and possesses internal magnetic fields.
http://www.merriam-webster.com/dictionary/plasma
https://en.wikipedia.org/wiki/Plasma_%28physics%29
An object which is naturally occuring, bound together by gravitational or electromagnetic forces, and surrounded by space.
celestial body
envoAstro
Astronomical bodies are usually cohesive, thus the use of the term 'object' sensu BFO 'object'.
astronomical body
An object which is naturally occuring, bound together by gravitational or electromagnetic forces, and surrounded by space.
https://en.wikipedia.org/wiki/Astronomical_object
A planet is an astronomical body orbiting a star or stellar remnant that is massive enough to be rounded by its own gravity, is not massive enough to cause thermonuclear fusion, and has cleared its neighbouring region of planetesimals.
envoAstro
envoPolar
Considerable debate on the definition of planet exists.
planet
A planet is an astronomical body orbiting a star or stellar remnant that is massive enough to be rounded by its own gravity, is not massive enough to cause thermonuclear fusion, and has cleared its neighbouring region of planetesimals.
http://solarsystem.nasa.gov/planets/whatisaplanet
https://en.wikipedia.org/wiki/Planet
1
An object which is composed of one or more gravitationally bound structures that are associated with a position in space.
celestial object
envoAstro
If there is only one astronomical body involved, this class is equivalent to ENVO:01000799. This may be problematic with reasoning, but it seems to be true to the rather fuzzy definitions found thus far.
astronomical object
An object which is composed of one or more gravitationally bound structures that are associated with a position in space.
https://en.wikipedia.org/wiki/Astronomical_object
An environmental material which is in a solid state.
This is a defined class: its subclasses will not be asserted, but filled by inference.
solid environmental material
An environmental material which is in a liquid state.
envoPolar
This is a defined class: its subclasses will not be asserted, but filled by inference.
liquid environmental material
A biosphere is a part of an astronomical body which includes, as parts, all the living entities within the gravitational sphere of influence of that body, as well as the non-living and dead entities with which they interact.
Whether this class should be grouped with classes such as "hydrosphere" and "cryosphere" requires some discussion.
envoAstro
envoPolar
The gravitational sphere of influence referenced in this class' definition is the Hill sphere: a region in which an object dominates the attraction of satellites despite gravitational perturbations.
biosphere
A biosphere is a part of an astronomical body which includes, as parts, all the living entities within the gravitational sphere of influence of that body, as well as the non-living and dead entities with which they interact.
http://www.biology-online.org/dictionary/Biosphere
https://en.wikipedia.org/wiki/Biosphere
A cryosphere is that part of a planet which is primarily composed of water is in solid form.
envoAstro
envoPolar
This is a very broad and, in practice, poorly defined term. Please consider using or requesting a more specific class.
cryosphere
A cryosphere is that part of a planet which is primarily composed of water is in solid form.
https://en.wikipedia.org/wiki/Cryosphere
An astronomical body part which is composed of the combined mass of water found on, under, and over the surface of a planet.
envoAstro
envoPolar
This is a very broad and, in practice, poorly defined term. Please consider using or requesting a more specific class.
hydrosphere
An astronomical body part which is composed of the combined mass of water found on, under, and over the surface of a planet.
https://en.wikipedia.org/wiki/Hydrosphere
An astronomical body part which is composed of soil, subject to soil formation processes, and found on the surface of a lithosphere.
envoAstro
This is a very broad and, in practice, poorly defined term. Please consider using or requesting a more specific class.
pedosphere
An astronomical body part which is composed of soil, subject to soil formation processes, and found on the surface of a lithosphere.
https://en.wikipedia.org/wiki/Pedosphere
A precipitation process is a process in which a portion of some substance segregates from a material in which that substance or its precursors were dissolved or suspended in and settles due to a force such as gravity or centrifugal force.
precipitation process
A precipitation process is a process in which a portion of some substance segregates from a material in which that substance or its precursors were dissolved or suspended in and settles due to a force such as gravity or centrifugal force.
https://en.wikipedia.org/wiki/Precipitation_%28chemistry%29
https://en.wikipedia.org/wiki/Precipitation
A hydrological process in which irregular aggregates of snow fall to a planetary surface.
snow fall
environmental_hazards
envoPolar
snowfall
An envirommental system which bridges two or more biomes and which includes ecological communities which blend these biomes' phylogenetic and phenotypic compositions.
There are many subtypes of ecotone, some with sharp transitions and others with gradual, patchy transitions between communities. From Wikipedia:Ecotone - The word ecotone was coined from a combination of eco(logy) plus -tone, from the Greek tonos or tension – in other words, a place where ecologies are in tension.
ecotone
An envirommental system which bridges two or more biomes and which includes ecological communities which blend these biomes' phylogenetic and phenotypic compositions.
ISBN:978-0-03-058414-5
https://en.wikipedia.org/wiki/Ecotone
https://github.com/EnvironmentOntology/envo/issues/501
https://www.merriam-webster.com/dictionary/ecotone
An environmental system in which minimal to no anthropisation has occurred and non-human agents are the primary determinants of the system's dynamics and composition.
non-anthropised environment
non-anthropized environment
In most contexts, 'natural' is defined by the lack of intervention or influence by humans and their activities. On Earth, most environments fall on a scale between completely natural and anthropised.
natural environment
An environmental system in which minimal to no anthropisation has occurred and non-human agents are the primary determinants of the system's dynamics and composition.
https://en.wikipedia.org/wiki/Anthropization
https://en.wikipedia.org/wiki/Natural_environment
A process during which a natural environmental system is altered by human action.
anthropization
An area may be classified as anthropized even though it looks natural, such as grasslands that have been deforested by humans. It can be difficult to determine how much a site has been anthropized in the case of urbanization because one must be able to estimate the state of the landscape before significant human action.
anthropisation
A process during which a natural environmental system is altered by human action.
https://en.wikipedia.org/wiki/Anthropization
An area may be classified as anthropized even though it looks natural, such as grasslands that have been deforested by humans. It can be difficult to determine how much a site has been anthropized in the case of urbanization because one must be able to estimate the state of the landscape before significant human action.
https://en.wikipedia.org/wiki/Anthropization
An ecotone which overlaps at least one biome which supports the growth and persistence of trees and at least one that does not. Before ceasing altogether, tree growth becomes sparse and trees appear stunted as conditions become less favourable along this ecotone.
tree line
tree-line
treeline
tree line ecotone
An ecotone which overlaps at least one biome which supports the growth and persistence of trees and at least one that does not. Before ceasing altogether, tree growth becomes sparse and trees appear stunted as conditions become less favourable along this ecotone.
https://en.wikipedia.org/wiki/Tree_line
A planet that is composed primarily of silicate rocks or metals.
rocky planet
telluric planet
Earth-like planet
envoAstro
terrestrial planet
A planet that is composed primarily of silicate rocks or metals.
https://en.wikipedia.org/wiki/Terrestrial_planet
A process whereby a volume of liquid moves due to a disequilibrium of physical forces.
envoPolar
This class can refer to the flow of any material in a liquid phase.
mass liquid flow
A process whereby a volume of liquid moves due to a disequilibrium of physical forces.
https://en.wikipedia.org/wiki/Wind
A process during which a volume of water is transported due to a disequilibria in physical forces.
environmental_hazards
water flow process
A part of an astronomical body which includes, as parts, all the entities which have been constructed or manufactured by humans or their technology and which are within the gravitational sphere of influence of that body.
envoAstro
The gravitational sphere of influence referenced in this class' definition is the Hill sphere: a region in which an object dominates the attraction of satellites despite gravitational perturbations.
technosphere
A part of an astronomical body which includes, as parts, all the entities which have been constructed or manufactured by humans or their technology and which are within the gravitational sphere of influence of that body.
http://dx.doi.org/10.1177/2053019616677743
http://www.yourdictionary.com/technosphere
https://www.sciencedaily.com/releases/2016/11/161130085021.htm
A planned process during which raw or recycled materials are transformed into products for use or sale using labour and machines, tools, chemical and biological processing, or formulation.
The term may refer to a range of human activity, from handicraft to high tech, but is most commonly applied to industrial production, in which raw materials are transformed into finished goods on a large scale.
manufacturing process
A planned process during which raw or recycled materials are transformed into products for use or sale using labour and machines, tools, chemical and biological processing, or formulation.
https://en.wikipedia.org/wiki/Manufacturing
The term may refer to a range of human activity, from handicraft to high tech, but is most commonly applied to industrial production, in which raw materials are transformed into finished goods on a large scale.
https://en.wikipedia.org/wiki/Manufacturing
An process during which natural or manufactured materials and products are processed and arranged by humans or their technology into structures.
The nature of "structures" must be further specified.
human-directed construction process
An environmental system within which an environmental material strongly influences the system's composition and properties.
Organisational class. Not intended for annotation. Subclasses describe environments which are usually permeated by an environmental material. They may also describe environments which are sufficiently close to a material, that their dynamics are strongly influenced by it (e.g. a patch of forest ecosystem neighbouring a uranium dump).
environmental system determined by a material
An environmental system which is determined by a living organism.
host-associated environment
envoEmpo
envoOmics
environmental system determined by an organism
A meteor is any matter- or energy-based entity which is located in the atmosphere of an astronomical body.
envoAtmo
meteor
A meteor is any matter- or energy-based entity which is located in the atmosphere of an astronomical body.
https://cloudatlas.wmo.int/other-meteors.html
A meteor which is primarily composed of water.
envoAtmo
hydrometeor
A meteor which is primarily composed of water.
https://cloudatlas.wmo.int/other-meteors.html
A meteor which is primarily composed of rock.
envoAtmo
lithometeor
A lake which has formed as the result of processes that are not or are only minimally driven by human activity.
This class is to be filled by inference.
natural lake
A process during which energy is emitted or transmitted in the form of waves or particles through space or a material medium.
Requires addition of waves for full axiomatisation. This should be linked to "subatomic particle" with an "or". Note that ENVO represents space as an environmental material (a hard vacuum with sparse material inclusions).
environmental_hazards
envoAstro
radiation
A process during which energy is emitted or transmitted in the form of waves or particles through space or a material medium.
https://en.wikipedia.org/wiki/Radiation
A radiation process during which waves (or their quanta, photons) of the electromagnetic field propagate (radiate) through space carrying electromagnetic energy.
EM radiation
environmental_hazards
envoAstro
Note that this class is concerned only with active radiative processes: static electric and magnetic fields are not inlcuded. All electromagnetic radiation carries radiant energy.
electromagnetic radiation
A radiation process during which waves (or their quanta, photons) of the electromagnetic field propagate (radiate) through space carrying electromagnetic energy.
https://en.wikipedia.org/wiki/Electromagnetic_radiation
An environmental system which has its properties and dynamics determined by soil.
Soil (non-saline)
envoEmpo
envoOmics
soil environment
Soil (non-saline)
http://press.igsb.anl.gov/earthmicrobiome/protocols-and-standards/emp-ontology-empo/
An environmental system which has its properties and dynamics determined by sediment.
envoEmpo
envoOmics
sediment environment
An environmental system which has its properties and dynamics determined by an aerosol.
envoEmpo
envoOmics
aerosol environment
An environmental system which has its properties and dynamics determined by a saline aerosol.
Aerosol (saline)
envoEmpo
envoOmics
saline aerosol environment
Aerosol (saline)
http://press.igsb.anl.gov/earthmicrobiome/protocols-and-standards/emp-ontology-empo/
seaspray or other aerosolized saline material (>5 psu)
An environmental system which has its properties and dynamics determined by an aerosol with a low concentration of dissolved solutes.
Aerosol (non-saline)
envoEmpo
envoOmics
non-saline aerosol environment
Aerosol (non-saline)
http://press.igsb.anl.gov/earthmicrobiome/protocols-and-standards/emp-ontology-empo/
aerosolized dust or liquid
An environmental system determined by part of a living or dead plant, or a whole small plant.
Plant corpus
envoEmpo
envoMeo
envoOmics
environment associated with a plant part or small plant
Plant corpus
http://press.igsb.anl.gov/earthmicrobiome/protocols-and-standards/emp-ontology-empo/
An astronomical body which is composed of rocky or metallic materials and is considerably smaller than asteroids.
envoAstro
meteoroid
An astronomical body which is composed of rocky or metallic materials and is considerably smaller than asteroids.
https://en.wikipedia.org/wiki/Meteoroid
A material which is composed primarily of one or more pure metals and which shows their properties.
Far more axiomatisation can be done should the qualities of metals be added to PATO or a similar quality ontology. However, note that there are many exceptions to the typical qualities of the majority of metals.
metal
While this class allows for some degree of contamination by non-metal substances, the material represented should show at least some of the typical features of a pure metal: hardness (except for liquid metals), opacity, lustre, malleability, fusibility, ductile and good electrical and thermal conductivity.
metallic material
A material which is composed primarily of one or more pure metals and which shows their properties.
https://en.wikipedia.org/wiki/Metal
The disposition of an environmental system, particularly those influencing atmospheres, to manifest a cyclic pattern of weather over time.
The current alignment of "climate" under BFO:disposition is drawing from its very useful etymology (Ancient Greek klima, meaning inclination). The climatic conditions currently used to axiomatise biomes (polar, tropical, etc) may be better placed under this class.
Climate is commonly defined as the weather averaged, or otherwise summarised, over a period of time much longer than the duration of any phenomenon that constitutes weather. The standard averaging period is 30 years, but other periods may be used depending on the purpose.
climate
The disposition of an environmental system, particularly those influencing atmospheres, to manifest a cyclic pattern of weather over time.
https://en.wikipedia.org/wiki/Climate
Climate is commonly defined as the weather averaged, or otherwise summarised, over a period of time much longer than the duration of any phenomenon that constitutes weather. The standard averaging period is 30 years, but other periods may be used depending on the purpose.
https://en.wikipedia.org/wiki/Climate
A process during which microscopic solid or liquid objects are formed.
particle formation
particulate matter formation process
A process during which microscopic solid or liquid objects are formed.
https://en.wikipedia.org/wiki/Particulates
An aerosol formation process which occurs in an atmosphere.
atmospheric aerosol formation
envoAtmo
atmospheric aerosol formation
An aerosol formation process which occurs in an atmosphere.
https://en.wikipedia.org/wiki/Particulates
A process during which an aerosol, consisting of solid particulates suspended in a gas, is formed in an atmosphere.
formation of solid particles in an atmosphere
envoAtmo
formation of a solid aerosol in an atmosphere
A process during which an aerosol, consisting of solid particulates suspended in a gas, is formed in an atmosphere.
https://en.wikipedia.org/wiki/Particulates
A process during which an aerosol, consisting of droplets of liquid suspended in gas, is formed in an atmosphere.
formation of liquid droplets in an atmosphere
formation of liquid particles in an atmosphere
envoAtmo
formation of a liquid aerosol in an atmosphere
A process during which an aerosol, consisting of droplets of liquid suspended in gas, is formed in an atmosphere.
https://en.wikipedia.org/wiki/Particulates
An aerosol which has non-gaseous parts that are primarily composed of liquid droplets.
SWEETRealm:Aerosol
liquid aerosol
envoAtmo
aerosolised liquids
An aerosol which has non-gaseous parts that are primarily composed of liquid droplets.
https://en.wikipedia.org/wiki/Aerosol
An aerosol which has non-gaseous parts that are primarily composed of solid particles.
SWEETRealm:Aerosol
solid aerosol
envoAtmo
aerosolised solids
An aerosol which has non-gaseous parts that are primarily composed of solid particles.
https://en.wikipedia.org/wiki/Aerosol
A process during which microscopic solid particulates are formed from gaseous materials in an atmosphere.
atmospheric formation of a solid aerosol
formation of a solid aerosol in an atmosphere
formation of a solid aerosol in the atmosphere
formation of solid particles from gaseous material in an atmosphere
envoAtmo
formation of a solid aerosol from gaseous material in an atmosphere
A process during which microscopic solid particulates are formed from gaseous materials in an atmosphere.
https://en.wikipedia.org/wiki/Particulates
A process during which microscopic liquid droplets are formed from gaseous materials in an atmosphere.
atmospheric formation of a liquid aerosol
formation of a liquid aerosol in an atmosphere
formation of a liquid aerosol in the atmosphere
formation of liquid droplets from gaseous material in an atmosphere
formation of liquid particles from gaseous material in an atmosphere
envoAtmo
formation of a liquid aerosol from gaseous material in an atmosphere
A process during which microscopic liquid droplets are formed from gaseous materials in an atmosphere.
https://en.wikipedia.org/wiki/Particulates
A process during which pieces of a planetary crust and uppermost mantle move.
tectonic movement
A process during which pieces of a planetary crust and uppermost mantle move.
https://en.wikipedia.org/wiki/Plate_tectonics
https://en.wikipedia.org/wiki/List_of_tectonic_plates
A part of a lithosphere which is separated by other such parts by geographic faults or similar geomorphological discontinuities.
tectonic plate
A part of a lithosphere which is separated by other such parts by geographic faults or similar geomorphological discontinuities.
https://en.wikipedia.org/wiki/List_of_tectonic_plates
A geomorphological feature which is formed where two or more tectonic plates move towards, away from, or along one another, resulting in deformation of the lithosphere.
tectonic plate boundary
A geomorphological feature which is formed where two or more tectonic plates move towards, away from, or along one another, resulting in deformation of the lithosphere.
https://en.wikipedia.org/wiki/Plate_tectonics
An ice is an environmental material which is either frozen or which is maintained in a solid state by gravitational forces or pressure.
This class is defined logically - any material that is frozen is considered a subclass. Note that ice may be formed at very high temperatures, due to gravitational effects and/or pressure.
ice
A terrestrial planet which has a surface dominated by hot deserts.
dry planet
envoAstro
This class of planet is still mostly theoretical.
desert planet
A planet which has a surface layer that nearly completely or completely covered by water, and which has a substantial portion of its mass composed of water.
An axiom to express that the planet has a 'substantial' proportion of its mass in the form of water wound enhance this class.
aquaplanet
panthalassic planet
water world
envoAstro
While this planetary form is still mostly theoretical, strong candidates exist such as the extrasolar planet GJ 1214 b and ocean planet candidate Kepler-22b.
ocean planet
A planet which has a surface layer that nearly completely or completely covered by water, and which has a substantial portion of its mass composed of water.
https://en.wikipedia.org/wiki/Ocean_planet
A planet which has a surface layer that nearly completely or completely covered by ice, and which has a substantial portion of its mass composed of ice.
cryoplanet
envoAstro
While this planetary form is still mostly theoretical, strong candidates exist such as OGLE-2005-BLG-390Lb, OGLE-2013-BLG-0341L b and MOA-2007-BLG-192Lb. Pluto was considered an ice planet until its reclassification in 2006 CE. Surface temperatures of ice planets would have to be below 260 K (−13°C) if composed primarily of water, below 180 K (−93°C) if primarily composed of CO2 and ammonia, and below 80 K (−193°C) if composed primarily of methane.
ice planet
A planet which has a surface layer that nearly completely or completely covered by ice, and which has a substantial portion of its mass composed of ice.
https://en.wikipedia.org/wiki/Ice_planet
While this planetary form is still mostly theoretical, strong candidates exist such as OGLE-2005-BLG-390Lb, OGLE-2013-BLG-0341L b and MOA-2007-BLG-192Lb. Pluto was considered an ice planet until its reclassification in 2006 CE. Surface temperatures of ice planets would have to be below 260 K (−13°C) if composed primarily of water, below 180 K (−93°C) if primarily composed of CO2 and ammonia, and below 80 K (−193°C) if composed primarily of methane.
https://en.wikipedia.org/wiki/Ice_planet
A planet which has a surface layer that nearly completely or completely covered by lava, and which has a substantial portion of its mass composed of lava.
envoAstro
This class of planets is still mostly theoretical, however, lava planets are thought plausible shortly after a terrestrial planet is formed, soon after a terrestrial planet has suffered a large collision event, or if a terrestrial planet is orbiting very close to its star, causing intense irradiation and tidal forces. Likely lava exoplanets include COROT-7b, Kepler-10b, Alpha Centauri Bb, and Kepler-78b.
lava planet
A planet which has a surface layer that nearly completely or completely covered by lava, and which has a substantial portion of its mass composed of lava.
https://en.wikipedia.org/wiki/Lava_planet
This class of planets is still mostly theoretical, however, lava planets are thought plausible shortly after a terrestrial planet is formed, soon after a terrestrial planet has suffered a large collision event, or if a terrestrial planet is orbiting very close to its star, causing intense irradiation and tidal forces. Likely lava exoplanets include COROT-7b, Kepler-10b, Alpha Centauri Bb, and Kepler-78b.
https://en.wikipedia.org/wiki/Lava_planet
A quality which inheres in a astronomical body or astronomical body part by virtue of the variation in its material composition, participation in geological processes, and the variation in is land- and hydroforms.
Materials which are usually assessed when appraising geodiversity include minerals, rocks, sediments, fossils, soils and water. Landforms factored into geodiversity metrics typically include folds, faults, and other expressions of morphology or relations between units of earth material. Natural processes that are included in measures of geodiversity are those which either maintain or change materials or geoforms, including tectonics, sediment transport, and pedogenesis. Geodiversity does not usually factor in anthropogenic entities.
geodiversity
A quality which inheres in a astronomical body or astronomical body part by virtue of the variation in its material composition, participation in geological processes, and the variation in is land- and hydroforms.
https://en.wikipedia.org/wiki/Geodiversity
Materials which are usually assessed when appraising geodiversity include minerals, rocks, sediments, fossils, soils and water. Landforms factored into geodiversity metrics typically include folds, faults, and other expressions of morphology or relations between units of earth material. Natural processes that are included in measures of geodiversity are those which either maintain or change materials or geoforms, including tectonics, sediment transport, and pedogenesis. Geodiversity does not usually factor in anthropogenic entities.
An ecosystem which has been causally isolated from a larger ecosystem within which it was previously embedded, such that the direct exchange of materials, resources, and energy between these systems is severely or entirely curtailed.
Often, ecosystem fragments are unable to sustain themselves without human intervention and management as they are not large enough to perform self-sustaining functions (e.g. nutrient recycling) or hold sufficient ecological resources such as genetic diversity of populations.
ecosystem fragment
A process during which one or more parts of an ecosystem become causally isolated such that the direct flow or exchange of materials, resources, and energy between a given fragment and the remainder of the original system is severely curtailed or entirely halted.
ecosystem fragmentation process
A process during which one or more parts of an ecosystem become causally isolated such that the direct flow or exchange of materials, resources, and energy between a given fragment and the remainder of the original system is severely curtailed or entirely halted.
https://en.wikipedia.org/wiki/Ecosystem_decay
https://en.wikipedia.org/wiki/Habitat_fragmentation
https://en.wikipedia.org/wiki/Population_fragmentation
A process during which an ecosystem, its parts, or the processes it participates in are modified by human intervention to accomplish an objective.
ecosystem management
Umweltmaßnahme
environmental management
active ecosystem management process
A process during which an ecosystem, its parts, or the processes it participates in are modified by human intervention to accomplish an objective.
https://www.iucn.org/theme/protected-areas/about/protected-areas-categories/category-iv-habitatspecies-management-area
Umweltmaßnahme
https://orcid.org/0000-0002-9620-2832
www.awi.de/internas
1
A process during which an ecosystem fragment loses its system integrity, with many of its resident ecological populations 1) losing their habitats, 2) undergoing a loss of functional and phylogenetic diversity, and 3) undergoing a subsequent genetic destabilisation through inbreeding.
This process may be caused by direct anthropisation (i.e. the fragmentation of ecosystems due to the establishment of cropland) or by more natural events such as forest fires or erosion of land bridges.
ecosystem decay
A process during which an ecosystem fragment loses its system integrity, with many of its resident ecological populations 1) losing their habitats, 2) undergoing a loss of functional and phylogenetic diversity, and 3) undergoing a subsequent genetic destabilisation through inbreeding.
https://en.wikipedia.org/wiki/Ecosystem_decay
Soil which has increased levels of molecules or ions capable of donating a hydron (proton or hydrogen ion) to other chemical entities, or, alternatively, capable of forming covalent bonds with other chemicals via the acceptance of an electron pair, resulting in a bulk pH measurement of less than 7.
acidic soil
Soil which has increased levels of molecules or ions capable of donating a hydron (proton or hydrogen ion) to other chemical entities, or, alternatively, capable of forming covalent bonds with other chemicals via the acceptance of an electron pair, resulting in a bulk pH measurement of less than 7.
https://en.wikipedia.org/wiki/Acid
The surface layer of a volume of water.
EcoLexicon:surface_water
SWEETRealm:SurfaceWater
https://en.wikipedia.org/wiki/Surface_water
surface of a body of water
water body surface
water surface
The surface layer of a mass of sediment.
surface of a sedimentary mass
surface sediment
sediment surface
An environmental zone which is bounded by material parts of a land mass or the atmosphere or space adjacent to it.
terrestrial environmental zone
A terrestrial zone which is bounded by constructed, manufactured, or other anthropogenic material entities.
anthropised terrestrial environmental zone
An environmental zone which is bounded by material parts of a marine environment.
This class will eventually be populated by inference alone, with its subclasses distributed in more process-linked hierarchies to improve semantic density.
marine environmental zone
A process during which sediments compact under pressure, expel connate fluids, and gradually become solid sedimentary rock.
lithification
A process during which sediments compact under pressure, expel connate fluids, and gradually become solid sedimentary rock.
https://en.wikipedia.org/wiki/Lithification
A natural environment which is located on a land mass.
terrestrial natural environment
A natural environment which is within a water body.
aquatic natural environment
A layer which is primarily composed of some liquid material.
liquid layer
A layer which is primarily composed of some solid material, allowing for non-solid parts such as interstitial pockets of gas or liquid.
solid layer
A solid layer which is primarily composed of some water-based ice.
water ice layer
An environmental zone which is part of an atmosphere.
atmospheric area
atmospheric zone
A vegetated area is a geographic feature which has ground cover dominated by plant communities.
ORCID:0000-0002-4366-3088
envoPolar
vegetated area
A geographic feature which is primarily composed of a continuous volume of liquid water held in shape or sustained by an environmental process.
Should create links to envrionmental process with new relation like "sustained_by"
Similar, in spirit, to landform.
hydroform
Should create links to envrionmental process with new relation like "sustained_by"
ORCID:0000-0002-4366-3088
A liquid surface layer which is in contact with air.
liquid air-water interface layer
A surface layer which is composed primarily of some liquid.
liquid surface layer
A surface layer which is composed primarily of solid environmental material.
solid surface layer
A body of water which is primarily composed of saline water.
saline body of water
This class has its subclasses populated by inference.
saline water body
A material transport process during which a volume of material is displaced due to a disequilibrium in physical forces and during which 1) the qualities that inhere in that volume and 2) the processes that are unfolding within it are largely unchanged.
advective transport
Advective processes are disjoint from diffusive processes. Typically, fluids are advected.
advective transport process
A material transport process during which a volume of material is displaced due to a disequilibrium in physical forces and during which 1) the qualities that inhere in that volume and 2) the processes that are unfolding within it are largely unchanged.
https://en.wikipedia.org/wiki/Advection
https://en.wikipedia.org/wiki/Intensive_and_extensive_properties
An action of exogenic processes (such as water flow or wind) which remove environmental material from one location on the surface of an astronomical body, transporting it to another location where it is deposited.
erosion
An action of exogenic processes (such as water flow or wind) which remove environmental material from one location on the surface of an astronomical body, transporting it to another location where it is deposited.
https://en.wikipedia.org/wiki/Erosion
A landform which has been rendered barren or partially barren by environmental extremes, especially by low rainfall.
desert
A system which consists of an atmosphere, hydrosphere, cryosphere, land surface, and biosphere, forced or influenced by external processes.
This class, from the IPCC report, is naturally focused on the Earth's climate. The report cites the Sun as the agent of the most important forcing processes. It also considers the direct effect of human activities on the climate system an external forcing
climate system
A system which consists of an atmosphere, hydrosphere, cryosphere, land surface, and biosphere, forced or influenced by external processes.
https://github.com/EnvironmentOntology/envo/issues/604
https://www.ipcc.ch/ipccreports/tar/wg1/040.htm
This class, from the IPCC report, is naturally focused on the Earth's climate. The report cites the Sun as the agent of the most important forcing processes. It also considers the direct effect of human activities on the climate system an external forcing
https://www.ipcc.ch/ipccreports/tar/wg1/040.htm
A process during which particles suspended in a gaseous medium are formed.
new particle formation process
envoAtmo
aerosolised particle formation process
A process during which particles suspended in a gaseous medium are formed.
https://en.wikipedia.org/wiki/Aerosol
https://en.wikipedia.org/wiki/Particulates
A material transport process during which solid or liquid particles are directly introduced into a volume of gas.
primary aerosol formation
primary aerosol formation process
A material transport process during which solid or liquid particles are directly introduced into a volume of gas.
https://en.wikipedia.org/wiki/Aerosol
https://en.wikipedia.org/wiki/Particulates
An ecosystem which 1) typically has monthly average temperatures below 10 degrees Celsius 2) has a low evapotranspiration ratio 3) is dominated by treeless terrain, covered by communities of low-growing vegetation such as dwarf shrubs, sedges and grasses, mosses, and lichens, 4) contains areas of soil underlain by permafrost with a thin active layer and 5) occurs in both polar and alpine regions (i.e., both high latitudes and high altitudes), and 5) does not have permanent snow or ice cover.
SPIRE:Tundra
envoPolar
Tundra ecosysems are often underlaid by permafrost, with the result that drainage is bad and the soil may be saturated for long periods. It does not have a permanent snow-ice cover. Productivity is low in this biome because of the extremes of climate.
tundra ecosystem
An ecosystem which 1) typically has monthly average temperatures below 10 degrees Celsius 2) has a low evapotranspiration ratio 3) is dominated by treeless terrain, covered by communities of low-growing vegetation such as dwarf shrubs, sedges and grasses, mosses, and lichens, 4) contains areas of soil underlain by permafrost with a thin active layer and 5) occurs in both polar and alpine regions (i.e., both high latitudes and high altitudes), and 5) does not have permanent snow or ice cover.
This definition is a synthesis of the following sources: NSIDC Glossary accessed 2016, IPCC WGII AR5 2014, Van Everdingen International Permafrost Association 2005, AMS - glossary of meteorology, PhysicalGeography.net
A bed which underlies a marine water body.
marine bed
Clay which is part of an abyssal plain.
abyssal clay
A mining process during which materials are extracted from benthic environments deep below the ocean surface, where no stellar radiation reaches..
deep seafloor mining
deep-seafloor mining
"The most valuable of the marine mineral resources is petroleum. About 15% of the world's oil is produced offshore, and extraction capabilities are advancing. One of the largest environmental impacts of deep sea mining are discharged sediment plumes which disperse with ocean currents and thus may negatively influence the marine ecosystem. Coal deposits known as extensions of land deposits , are mined under the sea floor in Japan and England."
benthic deep-sea mining
A mining process during which materials are extracted from benthic environments deep below the ocean surface, where no stellar radiation reaches..
https://en.wikipedia.org/wiki/Mining
https://www.eionet.europa.eu/gemet/en/concept/14956
"The most valuable of the marine mineral resources is petroleum. About 15% of the world's oil is produced offshore, and extraction capabilities are advancing. One of the largest environmental impacts of deep sea mining are discharged sediment plumes which disperse with ocean currents and thus may negatively influence the marine ecosystem. Coal deposits known as extensions of land deposits , are mined under the sea floor in Japan and England."
https://www.eionet.europa.eu/gemet/en/concept/14956
An anthropisation process during which terrestrial environments - natural or anthropised - or parts thereof are altered to facilitate human activities such as agriculture, settlement, or commerce.
land conversion
land development
Further examples include subdividing real estate into lots, typically for the purpose of building homes and converting unused factories into condominia.
land conversion process
An anthropisation process during which terrestrial environments - natural or anthropised - or parts thereof are altered to facilitate human activities such as agriculture, settlement, or commerce.
https://en.wikipedia.org/wiki/Land_development
Further examples include subdividing real estate into lots, typically for the purpose of building homes and converting unused factories into condominia.
https://en.wikipedia.org/wiki/Land_development
An anthropogenic environmental process which includes all human activities undertaken in a natural, semi-natural, or anthropised environment.
There are multiple systems of land use classification. This hierarchy aims to be generally applicable, but national systems can be added on request.
land use process
An anthropogenic environmental process which includes all human activities undertaken in a natural, semi-natural, or anthropised environment.
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/11493/144275.pdf
https://en.wikipedia.org/wiki/Land_use
A land use process during which materials of economic value are extracted from a planet, usually from an orebody, lode, vein, seam, reef or placer deposit.
mining
terrestrial mining
A land use process during which materials of economic value are extracted from a planet, usually from an orebody, lode, vein, seam, reef or placer deposit.
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/11493/144275.pdf
https://en.wikipedia.org/wiki/Land_use
https://en.wikipedia.org/wiki/Mining
https://www.eionet.europa.eu/gemet/en/concept/14837
A process during which an ecosystem - natural or anthropised - is changed by the actions of humans.
anthropogenic ecosystem conversion process
A planned process during which humans access and obtain resources, benefits, or services from a natural or anthropised ecosystem.
planned environmental usage process
A planned environmental usage process during which a non-renewable resource such as petroleum, natural gas, or water is extracted from an ecosystem.
mining
A planned environmental usage process during which a non-renewable resource such as petroleum, natural gas, or water is extracted from an ecosystem.
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/11493/144275.pdf
https://en.wikipedia.org/wiki/Land_use
https://en.wikipedia.org/wiki/Mining
https://www.eionet.europa.eu/gemet/en/concept/14837
A mining process which occurs in a marine ecosystem.
marine mining
A planned environmental usage process during which an environment supports manufacturing facilities producing commodities that are sold with the expectation of recovering the total cost of production.
This class includes environments used to support the facilities engaged with a broad variety of manufacturing activities from food and tobacco, to textiles, metals, vehicles, and chemicals.
usage of an environment for industry
A planned environmental usage process during which an environment supports manufacturing facilities producing commodities that are sold with the expectation of recovering the total cost of production.
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/11493/144275.pdf
https://en.wikipedia.org/wiki/Land_use
https://www.eionet.europa.eu/gemet/en/concept/4279
A mountain which is located on land and which is bounded by an atmosphere or outer space.
terrestrial mountain
A mountain that is part of a polar environment.
envoPolar
polar mountain
A mountain that is part of a polar environment.
https://www.unep-wcmc.org/resources-and-data/mountain-watch--environmental-change-sustainable-development-in-mountains
A mountain that is part of a temperate environment.
temperate mountain
A mountain that is part of a temperate environment.
https://www.unep-wcmc.org/resources-and-data/mountain-watch--environmental-change-sustainable-development-in-mountains
A mountain that is part of a tropical environment.
tropical mountain
A mountain that is part of a tropical environment.
https://www.unep-wcmc.org/resources-and-data/mountain-watch--environmental-change-sustainable-development-in-mountains
body of liquid
A part of an astronomical body which is primarily composed of a continuous volume of liquid material, shaped by one or more environmental processes.
liquid astronomical body part
A part of an astronomical body which is primarily composed of a continuous volume of liquid material, shaped by one or more environmental processes.
https://en.wikipedia.org/wiki/Landform
A part of an astronomical body which is primarily composed of a continuous volume of gaseous material, shaped by one or more environmental processes.
gaseous astronomical body part
A part of an astronomical body which is primarily composed of a continuous volume of gaseous material, shaped by one or more environmental processes.
https://en.wikipedia.org/wiki/Landform
A surface layer where the solid or liquid material of an astronomical body comes into contact with an atmosphere or outer space.
2018-10-04T16:55:57Z
a useful class: this can be used to define sub-terrestrial and sub-marine entities
surface of an astronomical body
A solid surface layer which is that part of a glacier in contact with a planetary atmosphere, water body, or solid material partially surrounding that glacier.
2019-01-14T15:39:35Z
glacier surface
glacial surface layer
A velocity quality which inheres in the surface layer of a glacier.
2019-01-14T15:42:21Z
glacier surface layer velocity
glacier surface velocity
glacial surface layer velocity
A material transformation process during which a material's viscosity increase either through a reduction in temperature, through chemical reactions, or other physical effects.
2019-01-14T18:47:32Z
congelation
congelation process
Sometimes the increase in viscosity is great enough to crystallize or solidify the substance in question.
material congelation process
A material transformation process during which a material's viscosity increase either through a reduction in temperature, through chemical reactions, or other physical effects.
https://en.wikipedia.org/wiki/Congelation
Sometimes the increase in viscosity is great enough to crystallize or solidify the substance in question.
https://en.wikipedia.org/wiki/Congelation
Land which is below the freezing point of water.
2019-01-14T21:18:19Z
http://sweetontology.net/realmCryo/FrozenGround
frozen ground
Perennially and seasonally frozen ground can vary from being partially to extensively frozen depending on the extent of the phase change. It may be described as hard frozen ground, plastic frozen ground, or dry frozen ground, depending on the pore ice and unfrozen water contents and its compressibility under load.
frozen land
Land which is below the freezing point of water.
https://orcid.org/0000-0003-4808-4736
Perennially and seasonally frozen ground can vary from being partially to extensively frozen depending on the extent of the phase change. It may be described as hard frozen ground, plastic frozen ground, or dry frozen ground, depending on the pore ice and unfrozen water contents and its compressibility under load.
https://orcid.org/0000-0003-4808-4736
Soil which is below the freezing point of water.
2019-01-14T21:26:59Z
frozen soil
An advective transport process during which a mass of ice is transported from one location to another.
2019-01-31T17:51:48Z
mass ice flow
A material congelation process during which a liquid turns into a solid when its temperature is lowered below its melting point.
2019-01-31T21:13:16Z
freezing
A material congelation process during which a liquid turns into a solid when its temperature is lowered below its melting point.
https://en.wikipedia.org/wiki/Freezing
A freezing process during which liquid water is transformed into water ice.
2019-01-31T21:16:46Z
freezing of water into water ice
A water surface that is part of a water body.
2019-02-27T21:22:13Z
surface layer of a water body
An ecoregion which is located on a landmass.
2019-03-05T17:40:44Z
https://www.worldwildlife.org/biome-categories/terrestrial-ecoregions
terrestrial ecoregion
A surface layer of a water body which is part of an ocean or sea.
2019-03-06T01:22:01Z
envoMarine
At this level, the depth of this layer is ambiguous. Some methods (telemetry) measure only the first few centimeters of the sea or ocean surface. In situ methods often sample the first few meters. Subclasses can be created for such cases.
sea surface layer
A layer which is part of a cryosphere.
2019-04-09T13:05:25Z
envoPolar
cryospheric layer
Permafrost which contains inclusions of water-based ice.
2019-04-09T13:45:40Z
ice-bearing permafrost
A material accumulation process during which the mass of snow on a surface increases.
2019-04-24T18:29:18Z
http://sweetontology.net/phenCryo/Accumulation
This term is used both as a process and as an amount of mass added. Semantically speaking these are two distinct concepts (e.g., accumulation results in accumulation_amount of ice or snow gain), though accumulation_amount would more likely be an attribute.
The scope of this term varies depending on the definition. Some definitions constrain themselves snow or ice added to glaciers; while others also include ice fields, snow cover, and/or floating ice. How to resolve this depends on the scope desired.
Some definitions include additional discussion of the the physics involved which would be useful for connecting glacier ontologies to atmospheric, hydrologic, etc. ontologies. This information should be captured no matter how the inconsistencies above are resolved.
snow accumulation process
A material accumulation process during which the mass of snow on a surface increases.
A material accumulation process during which ice forms in an environmental material or an existing accumulation of ice increases in mass.
2019-04-24T18:48:53Z
http://sweetontology.net/phenCryo/Accumulation
ice accumulation process
A material accumulation process during which ice forms in an environmental material or an existing accumulation of ice increases in mass.
A material accumulation process during which a accumulation of snow and ice forms or increases in mass.
2019-04-24T18:59:45Z
http://sweetontology.net/phenCryo/Accumulation
snow and ice accumulation process
A material accumulation process during which a accumulation of snow and ice forms or increases in mass.
A object which is composed primarily of water-based snow and ice.
2019-04-24T19:08:03Z
http://sweetontology.net/phenCryo/Accumulation
mass of ice and snow
A positional quality inhering in a bearer by virtue of the bearer being located within a glacier or ice sheet, between their summer surface or bed.
2019-04-24T19:51:34Z
englacial
An environmental system process which occurs within a glacier or ice sheet.
2019-04-24T19:59:58Z
http://sweetontology.net/phenCryo/Englacial
englacial process
An environmental system process which occurs within a glacier or ice sheet.
A process during which microscopic solid particulates are formed from liquid materials in an atmosphere.
2019-05-30T21:07:51Z
atmospheric formation of a solid aerosol
formation of a solid aerosol in an atmosphere
formation of a solid aerosol in the atmosphere
formation of solid particles from liquid material in an atmosphere
envoAtmo
formation of a solid aerosol from liquid material in an atmosphere
A process during which microscopic solid particulates are formed from liquid materials in an atmosphere.
https://en.wikipedia.org/wiki/Particulates
That part of an atmosphere which is composed of gaseous material.
2019-06-02T07:52:47Z
gaseous part of an atmosphere
A solid material which does not have a regularly organised internal structure.
2019-06-02T11:07:47Z
amorphous solid
An aerosol that is suspended in an atmosphere.
2019-06-03T12:24:09Z
atmospheric aerosol
A material transformation process during which solid or liquid particles form and are suspended in a mass of air, thus creating an aerosol.
2019-06-24T13:43:29Z
aerosol formation process
An environmental process which involves glaciers or ice sheets.
2019-06-24T17:12:30Z
Note that ice sheets and glaciers are confounded and confused in multiple communities and across multiple sources.
glacial process
Note that ice sheets and glaciers are confounded and confused in multiple communities and across multiple sources.
A surface layer which is composed primarily of some liquid or gas.
2019-08-20T08:28:42Z
fluid surface layer
A surface layer which separates two portions of fluid with respect to either 1) a discontinuity of some fluid property or 2) some derivative of one of these properties in a direction normal to the interface.
2019-07-22T17:29:44Z
fluid interface layer
A surface layer which separates two portions of fluid with respect to either 1) a discontinuity of some fluid property or 2) some derivative of one of these properties in a direction normal to the interface.
A layer which is composed primarily of some fluid.
2019-07-22T17:35:08Z
fluid layer
A fluid interface which separates two fluid masses with differing properties.
2019-07-22T17:43:32Z
fluid front
A fluid interface which separates two fluid masses with differing properties.
A fluid front which is composed primarily of gaseous material and separates at least two gaseous masses.
2019-07-22T17:50:08Z
gaseous front
A gaseous front which separates two masses of air with different densities and is a principal cause of meteorological phenomena.
2019-07-22T17:57:21Z
meteorological front
envoAtmo
This class refers to Earth's weather fronts. Other forms, not composed of air, are present on other planets and can be created on request. Note: "Since the temperature distribution is the most important regulator of atmospheric density, a front almost invariably separates air masses of different temperature. Along with the basic density criterion and the common temperature criterion, many other features may distinguish a front, such as a pressure trough, a change in wind direction, a moisture discontinuity, and certain characteristic cloud and precipitation forms."
weather front
A gaseous front which separates two masses of air with different densities and is a principal cause of meteorological phenomena.
This class refers to Earth's weather fronts. Other forms, not composed of air, are present on other planets and can be created on request. Note: "Since the temperature distribution is the most important regulator of atmospheric density, a front almost invariably separates air masses of different temperature. Along with the basic density criterion and the common temperature criterion, many other features may distinguish a front, such as a pressure trough, a change in wind direction, a moisture discontinuity, and certain characteristic cloud and precipitation forms."
An object which is composed of a continuous mass of air.
2019-08-20T07:54:32Z
envoAtmo
air mass
A fluid surface layer which is composed primarily of some gaseous material.
2019-08-20T08:30:01Z
gaseous surface layer
A layer which separates two portions of environmental material which possess 1) differing compositions, 2) a discontinuity of some property, or 3) some derivative of some property in a direction normal to the interface.
2019-08-20T09:28:10Z
interface layer
An object which is composed primarily of an environmental material
2019-08-20T09:38:29Z
This class and its subclasses refer to objects that are discrete accumulations of environmental materials, generally primarily composed of one or a few main material types.
mass of environmental material
An object which is composed primarily of a solid environmental material
2019-08-20T09:41:27Z
This class and its subclasses refer to objects that are discrete accumulations of environmental materials, generally primarily composed of one or a few main material types.
mass of solid material
An object which is composed primarily of a fluid.
2019-08-20T09:42:35Z
fluid mass
This class and its subclasses refer to objects that are discrete accumulations of environmental materials, generally primarily composed of one or a few main material types.
mass of fluid
An object which is composed primarily of a gas.
2019-08-20T09:44:01Z
gaseous mass
This class and its subclasses refer to objects that are discrete accumulations of environmental materials, generally primarily composed of one or a few main material types.
mass of gas
An object which is composed primarily of a liquid.
2019-08-20T09:45:03Z
liquid mass
This class and its subclasses refer to objects that are discrete accumulations of environmental materials, generally primarily composed of one or a few main material types.
mass of liquid
An mass of environmental materials which has appreciable quantities of several individual materials, such that the removal of one would convert the mass into a different entity.
2019-08-20T09:47:10Z
mass of compounded environmental materials
A weather front which separates air masses of tropical and polar origin.
2019-08-20T13:46:42Z
envoAtmo
envoPolar
polar front
A weather front which separates air masses of tropical and polar origin.
An environment which has a climate with continually high temperatures and with considerable precipitation, at least during part of the year.
2019-08-20T13:58:38Z
tropical environment
An environment which has a climate with continually high temperatures and with considerable precipitation, at least during part of the year.
An environment which is located in a part of an astronomical body subject to polar climatic conditions.
2019-08-20T14:53:26Z
polar environment
An environment which is located in a part of an astronomical body subject to polar climatic conditions.
An environment which is located in a part of an astronomical body subject to temperate climatic conditions.
2019-08-20T16:41:52Z
temperate environment
An environment which is located in a part of an astronomical body subject to temperate climatic conditions.
2019-09-05T05:47:26Z
mass fluid flow
An ecosystem in which the composition, structure, and function of resident ecological assemblages are primarily determined by a desert.
2019-10-17T08:21:08Z
desert ecosystem
A solid astronomical body part which is part of the landmass of that body.
2019-10-17T08:27:17Z
part of a landmass
A large continuous area of land, either surrounded by sea or contiguous with another landmass.
2019-10-17T08:31:26Z
landmass
A large continuous area of land, either surrounded by sea or contiguous with another landmass.
A part of an astronomical body which is primarily composed of a continuous medium bearing liquid, gaseous, and solid material in varying quantities.
2019-10-17T08:36:00Z
2018-10-04T13:59:22Z
ENVO:01001479
compound astronomical body part
A part of an astronomical body which is primarily composed of a continuous medium bearing liquid, gaseous, and solid material in varying quantities.
https://en.wikipedia.org/wiki/Landform
A surface layer of an astronomical body which is primarily composed of solid material and is not covered by oceans or other bodies of water.
2019-10-21T10:42:26Z
land
A surface layer of an astronomical body which is primarily composed of solid material and is not covered by oceans or other bodies of water.
2019-10-21T11:05:45Z
aquatic ecosystem
2019-10-21T11:06:11Z
marine ecosystem
2019-10-21T11:09:58Z
terrestrial ecosystem
An environmental process either driven by or primarily impacting the parts or emergent properties of an ecosystem.
2019-10-21T11:52:55Z
ecosystem process
A material entity which has been assembled through the intentional, instinctual, or deliberately programmed efforts of an organism or machine.
2019-10-29T14:50:34Z
construction
A biome which is subject to tropical climatic conditions.
2019-11-06T15:56:17Z
tropical biome
A biome which is subject to temperate climatic conditions.
2019-11-06T15:57:04Z
temperate biome
A biome which is subject to montane altitudinal conditions.
2019-11-06T16:00:33Z
montane biome
A biome which is subject to arid environmental conditions.
2019-11-06T16:06:47Z
arid biome
A process during which one entity loses energy to another entity.
2020-02-13T13:34:28Z
energy transfer process
A material accumulation process during which the volume of liquid entity increases.
2020-05-18T14:39:20Z
liquid accumulation process
Coastal water is a marine water body bordering a coast.
envoPolar
coastal water body
Coastal water is a marine water body bordering a coast.
https://en.wikipedia.org/wiki/Coastal
A combustible black or brownish-black sedimentary rock usually occurring in rock strata in layers or veins called coal beds or coal seams.
cjm
coal
A combustible black or brownish-black sedimentary rock usually occurring in rock strata in layers or veins called coal beds or coal seams.
Dust which is derived from coal.
cjm
coal dust
Dust which is derived from mineral material.
cjm
mineral dust
Dust which is composed primarily of some metallic material.
cjm
metallic dust
Dust which is derived from clay material.
cjm
clay dust
cjm
dust from plant parts
A liquid or a gas.
fluid
fluid environmental material
A liquid or a gas.
https://github.com/EnvironmentOntology/envo/issues/940
A type of land degradation in which terrestrial ecosystem becomes increasingly dry, typically losing its bodies of water as well as vegetation and wildlife.
desertification
A type of land degradation in which terrestrial ecosystem becomes increasingly dry, typically losing its bodies of water as well as vegetation and wildlife.
A process which occurs within an atmosphere.
This class will be populated by inference and is primarily organisational.
atmospheric process
A process which diminishes the functioning of an ecosystem located on land.
An SDGIO request. Likely to be refined and revised.
This could include, for example, reducing soil health, pollinator activity, or an ecosystem's ability to sequester carbon.
land degradation
A process which diminishes the functioning of an ecosystem located on land.
http://www.who.int/globalchange/ecosystems/desert/en/
https://en.wikipedia.org/wiki/Land_degradation
A process during which humans apply technology to alter the magnitude, duration, rate, or impact of an environmental process.
Relabel the obo foundry unique label to be generic process
anthropogenic modulatory intervention process
An environmental process which is driven by the action of humans.
anthropogenic environmental process
An action of exogenic processes (such as water flow or wind) which remove environmental material from one part of a planet's crust, transporting it to another location where it is deposited.
envoPolar
planetary erosion
An action of exogenic processes (such as water flow or wind) which remove environmental material from one part of a planet's crust, transporting it to another location where it is deposited.
https://en.wikipedia.org/wiki/Erosion
An environmental process which has water - in any of its states - as a participant.
This classes asserted subclasses will be moved away as it should be an inferred class.
hydrological process
Any water ice that is part of a glacier.
It is suggested that users complement this term with ice terms that are more descriptive of the ice itself, rather than its location/parthood.
http://orcid.org/0000-0002-3410-4655
envoPolar
glacial ice
Any water ice that is part of a glacier.
https://en.wikipedia.org/wiki/Glacier
A process during which the mass of one or more materials, present within a given site, increases.
http://orcid.org/0000-0002-3410-4655
envoPolar
Experimental class for structural purposes not recommended for annotation. A material accumulation process ends a material transport process.
material accumulation process
A process during which material is displaced from its original location and transported either to a new location or back to the original location.
http://orcid.org/0000-0002-3410-4655
envoPolar
Experimental class for structural purposes not recommended for annotation.
material transport process
A material transport process during which the snow and ice constituting a glacier, and anything contained within it, is transported down a slope by gravitation.
http://orcid.org/0000-0002-3410-4655
glacial flow
glacial movement
envoPolar
This must be differentiated from small ice masses simply falling or moving down slopes. In ENVO, this is a subclass of advective transport process, however, this may not be universally accepted by some which strictly limit advection to fluids.
glacial transport process
A depression which is part of a planetary crust, is of geographic scale, and is partially or completely enclosed.
The general semantics of depression and geographic basin are still to be worked out see https://github.com/EnvironmentOntology/envo/issues/486
http://orcid.org/0000-0002-3410-4655
envoPolar
geographic basin
A depression which is part of a planetary crust, is of geographic scale, and is partially or completely enclosed.
https://en.wikipedia.org/wiki/Basin
A material transport process during which one or more environmental materials are transported by the action of wind.
http://orcid.org/0000-0002-3410-4655
eolian
æolian
envoPolar
aeolian transport process
A material transport process during which one or more environmental materials are transported by the action of wind.
https://en.wikipedia.org/wiki/Aeolian_processes
Sediment which has been transported through the marine water column, settling on the seafloor.
http://orcid.org/0000-0002-3410-4655
marine sediments
envoPolar
Particles of marine sediment are primarily generated by 1) processes in terrestrial systems and transported to the marine realm by the action of rivers or aeolian processes (amongst other routes) , 2) marine organisms, 3) chemical processes in seawater, or 4) cosmogeneous input.
marine sediment
Sediment which has been transported through the marine water column, settling on the seafloor.
https://en.wikipedia.org/wiki/Pelagic_sediment#_note-8
A material accumulation process during which solid particles are pulled through a water body by gravitation or centrifugal force and which ends when they settle on a solid surface.
http://orcid.org/0000-0002-3410-4655
envoPolar
sedimentation in a water body
A process during which a portion of some environmental material is converted into a different material or a collection of materials.
A different material transformation process class (or similarly named class) pertaining to the conversion of a specific chemical into another belongs in CHEBI and or REX ontologies.
http://orcid.org/0000-0002-3410-4655
envoPolar
Experimental class for structural purposes not recommended for annotation. A material transformation process only refers to ENVO:environmental material classes (e.g. bulk and typically impure substances), rather than transformations converting a specific chemical into another.
material transformation process
A geographic feature which is primarily composed of a continuous mass of snow and/or ice.
Place holder class. Also the axiom should be changed to something along the lines of 'primairly composed of’ some ‘environmental material’ and ‘has quality’ frozen once PATO:frozen is imported.
http://orcid.org/0000-0002-3410-4655
envoPolar
cryoform
A mass of snow.
http://orcid.org/0000-0002-3410-4655
accumulation of snow
snow accumulation
http://sweetontology.net/phenCryo/Accumulation
envoPolar
snow mass
A surface layer which is composed primarily of soil.
2019-04-12T17:35:13Z
envoNceas
soil surface layer
The generation of energy for use by humans
cjm
2018-11-03T20:02:04Z
anthropogenic generation of energy
cjm
2018-11-03T20:04:34Z
generation of energy from coal
A disposition which is realized during the execution of work, the emission of heat, or the possession of mass.
cjm
2018-11-03T20:22:18Z
Consider replacing with PATO class; note that PATO class is not a disposition. This should likely go into OBO Core and also have a physicist look at it.
energy
Energy that it realized through motion.
cjm
2018-11-03T20:25:57Z
kinetic energy
A power station which burns a fossil fuel such as coal, natural gas, or petroleum to produce electricity.
cjm
2018-11-03T21:00:37Z
fossil fuel power plant
cjm
2018-11-03T21:01:16Z
coal power plant
A radiation process during which electromagnetic waves or their quanta are emitted at wavelengths between 10 nm and 400 nm.
To be expanded to account for subtypes.
UV radiation
ENVO
environmental_hazards
ultraviolet radiation
A radiation process during which electromagnetic waves or their quanta are emitted at wavelengths between 10 nm and 400 nm.
https://en.wikipedia.org/wiki/Ultraviolet
obsolete aggregate of governmental organizations
An aggregate of geopoliticial entities. Examples include the group of states of the United States, the nations of North America, and so on.
William R. Hogan
taken over by GEO_0000000401
obsolete group of governmental organizations
true
subcontinental land mass
2
An aggregate of organizations that is not itself a governmental organization, has only governmental organizations as members, and has at least two governmental organizations as members.
William R. Hogan
aggregate of governmental organizations
aggregate of contiguous land masses
geographical entity of astronomical body
A material entity that is (1) a bona fide or fiat object part of the crust, any bodies of liquid on or contained within the crust, or planetary boundary layer (if present) of a terrestrial planet (including Earth), dwarf planet, exoplanet, natural satellite, planetesimal, or small Solar System body, and that (2) overlaps the planetary surface (including having a boundary that coincides with part of the planetary surface).
Mathias Brochhausen
Matt Diller
William R. Hogan
Includes atmosphere, crust, geographical regions (e.g., the geographical region over which the state of Florida has jurisdiction), bodies of water, mountains, etc.
Generally, an individual organism is a distinct object that is not a part of the Earth, although this requires more thought. But the intent is definitely for this class to NOT subsume organism universally. Human beings are contained within, but not part of, the Earth, for example.
Note that despite the word 'planetary' in 'planetary surface', it refers generally to surface of dwarf planets, asteroids, moons, etc.
We note that not all planets have a surface per se (e.g., gas giants such as Jupiter and Saturn). So only planets, natural satellites, etc. with a planetary surface (with or without a planetary boundary layer) have geographical entities.
We note that the term 'geography' is also applied to the Earth's moon, Mars, Venus, and possibly even other moons and planets in our own solar system and beyond.
Thus, we are attempting to define things generally enough that they could be reused for the geographical entities/features on the Moon, Mars, other planets, exoplanets, other natural satellites (a.k.a moons), asteroids, etc.
geographical entity
A geographical entity that is demarcated at least in part by one or more closed fiat boundaries all of whose lines are part of the planetary surface.
François Modave
Mathias Brochhausen
Matt Diller
William R. Hogan
geographical region
continent
land mass
island
An object aggregate of geographical entities
aggregate of geographical entities
aggregate of islands
geopolitical organization
Amanda Hicks
geopoli organization
A governmental organization with a defined territory on which it exercises internal and external sovereignty, a permanent population, a government, and the capacity to enter into relations with other sovereign states.
William R. Hogan
de facto sovereign state
de facto state
nation
nation state
http://en.wikipedia.org/wiki/Sovereign_state
Per Wikipedia, the word 'nation' does not always refer to soverign states. For example, the "nation of Islam".
sovereign state
An organization that governs the people living in a particular geographical region or aggregate of geographical regions. The geographical region it governs can change over time (such as the westward expansion of the United States and the addition of Hawaii).
Note: this definition was taken over from "geopolitical organization".
Amanda Hicks
IMPORTANT: The label "geopolitical organization" was previously used for OMRSE_00000044 (governmental organization). "geopoli organization" is a label for a new and different class.
governmental organization
2
An object aggregate that is not itself a geopolitical organization and whose members are only geopolitical organizations that have some feature in common
Amanda Hicks
William R. Hogan
http://purl.obolibrary.org/obo/omrse.owl
aggregate of geopolitical organizations
2
An aggregate of governmental organizations that is not itself a sovereign state and whose members are only sovereign states that have some feature in common
William R. Hogan
http://purl.obolibrary.org/obo/omrse.owl
examples: all the sovereign states in North America, all the sovereign states with a GDP below or exceeding a particular quantity of money, all the sovereign states with a constitutional monarchy, all the sovereign states who belong to the U.N. (which is different than the U.N. itself), etc.
aggregate of sovereign states
planar angular measurement unit label
plane angle measurement unit label
The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.
mitochondrial inheritance
biological_process
mitochondrion inheritance
The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.
GOC:mcc
PMID:10873824
PMID:11389764
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
biological_process
mitochondrial genome maintenance
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
GOC:ai
GOC:vw
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
GO:0019952
GO:0050876
Wikipedia:Reproduction
reproductive physiological process
biological_process
reproduction
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
GOC:go_curators
GOC:isa_complete
GOC:jl
ISBN:0198506732
The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.
biological_process
vacuole inheritance
The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.
GOC:mcc
PMID:10873824
PMID:14616069
Interacting selectively and non-covalently with transfer RNA.
GO:0000946
base pairing with tRNA
molecular_function
tRNA binding
Interacting selectively and non-covalently with transfer RNA.
GOC:ai
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
microtubule cytoskeleton organisation
microtubule dynamics
biological_process
microtubule cytoskeleton organization and biogenesis
microtubule cytoskeleton organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
GOC:mah
microtubule cytoskeleton organisation
GOC:mah
microtubule dynamics
GOC:dph
GOC:tb
microtubule cytoskeleton organization and biogenesis
GOC:mah
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
nuclear interphase chromosome
cellular_component
nuclear chromosome
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
GOC:dph
GOC:mah
A chromosome found in the cytoplasm.
cytoplasmic interphase chromosome
cellular_component
cytoplasmic chromosome
A chromosome found in the cytoplasm.
GOC:mah
A chromosome found in the mitochondrion of a eukaryotic cell.
NIF_Subcellular:sao1186327184
mitochondrial DNA
mtDNA
cellular_component
mitochondrial genome
mitochondrial chromosome
A chromosome found in the mitochondrion of a eukaryotic cell.
GOC:mah
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
mitochondrial division
biological_process
mitochondrial proliferation
mitochondrial fission
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
PMID:11038192
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
GO:0007067
Wikipedia:Mitosis
biological_process
mitosis
mitotic cell cycle
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
GOC:mah
ISBN:0815316194
Reactome:69278
The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
biological_process
karyokinesis
nuclear division
The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
GOC:mah
A ribosome contained within a subcellular membrane-bounded organelle.
cellular_component
organellar ribosome
A ribosome contained within a subcellular membrane-bounded organelle.
GOC:mah
GOC:mcc
A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.
cellular_component
lytic vacuole
A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.
GOC:krc
The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.
Wikipedia:Autophagy_(cellular)#Selective_autophagy
Wikipedia:Mitophagy
mitochondrion autophagy
biological_process
mitophagy
autophagy of mitochondrion
The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.
GOC:autophagy
PMID:15798367
PMID:19289147
PMID:23065344
mitochondrion autophagy
GOC:autophagy
Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.
biological_process
cleavage during rRNA processing
cleavage involved in rRNA processing
Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.
GOC:curators
cleavage during rRNA processing
GOC:dph
GOC:tb
A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.
proteasome
26S proteasome
cellular_component
proteasome complex
A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.
GOC:rb
Wikipedia:Proteasome
proteasome
GOC:cjm
The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.
GO:0007335
Wikipedia:Karyogamy
nuclear fusion
nuclear fusion during karyogamy
biological_process
karyogamy
The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.
GOC:elh
The developmental process in which the size or shape of a cell is generated and organized.
GO:0007148
GO:0045790
GO:0045791
cellular morphogenesis
biological_process
cell morphogenesis
The developmental process in which the size or shape of a cell is generated and organized.
GOC:clt
GOC:dph
GOC:go_curators
GOC:tb
The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
biological_process
cell morphogenesis involved in differentiation
The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
GOC:go_curators
The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
biological_process
mitochondrial RNA catabolic process
The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
GOC:krc
GOC:mah
The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
biological_process
mitochondrial mRNA catabolic process
The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
GOC:krc
GOC:mah
The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
biological_process
mitochondrial RNA metabolic process
The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
GOC:krc
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
biological_process
regulation of mitochondrial RNA catabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
GOC:krc
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
biological_process
negative regulation of mitochondrial RNA catabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
GOC:krc
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
biological_process
positive regulation of mitochondrial RNA catabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
GOC:krc
GOC:mah
The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.
biological_process
mitochondrial RNA processing
The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.
GOC:krc
GOC:mah
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
kchris
2010-08-10T11:00:02Z
molecular_function
The word "promoter" is used variously in the literature to describe the core promoter specifically or the entire proximal regulatory region (excluding any distal enhancers) including both the core promoter and the upstream region where activating transcription factors such as Gal4 in S. cerevisiae or catabolite activator protein (CAP) in E. coli bind. To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" in order to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind, and "enhancer" regions which are typically more distal from the core promoter. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription. ANNOTATION NOTE: Regarding annotation to "transcription regulatory region DNA binding" (GO:0044212) and any of its is_a children, note that annotation to these terms specifies DNA binding only without any statement about transcription factor activity. To make an annotation about a function of transcription factor activity, consider "sequence-specific DNA-binding transcription factor activity" (GO:0003700) or its is_a children which have has_part relationships to the appropriate kind of "transcription regulatory region DNA binding".
transcription regulatory region sequence-specific DNA binding
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
GOC:txnOH
Interacting selectively and non-covalently with a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
kchris
2010-10-21T04:08:56Z
molecular_function
regulatory region nucleic acid binding
Interacting selectively and non-covalently with a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
GOC:txnOH
A process that results in a parallel arrangement of microtubules.
microtubule bundling
biological_process
microtubule bundle formation
A process that results in a parallel arrangement of microtubules.
GOC:dph
Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
translation initiation ternary complex assembly
biological_process
formation of translation initiation ternary complex
Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
GOC:hjd
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
hjd
2011-06-09T03:11:53Z
biological_process
Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms.
cytoplasmic translation
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
GOC:hjd
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.
hjd
2011-06-09T03:14:42Z
biological_process
cytoplasmic translational elongation
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.
GOC:hjd
The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
hjd
2011-06-09T03:15:48Z
biological_process
cytoplasmic translational initiation
The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
GOC:hjd
The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.
hjd
2011-06-09T03:17:13Z
biological_process
cytoplasmic translational termination
The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.
GOC:hjd
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
Wikipedia:Immune_system
biological_process
Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501).
immune system process
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GOC:add
GO_REF:0000022
Any process that modulates the frequency, rate, or extent of an immune system process.
biological_process
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
down regulation of immune system process
down-regulation of immune system process
downregulation of immune system process
inhibition of immune system process
biological_process
negative regulation of immune system process
Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
GOC:add
Any process that activates or increases the frequency, rate, or extent of an immune system process.
up regulation of immune system process
up-regulation of immune system process
upregulation of immune system process
activation of immune system process
stimulation of immune system process
biological_process
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
GOC:add
A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring.
puberty
biological_process
reproductive developmental process
developmental process involved in reproduction
A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring.
GOC:dph
GOC:isa_complete
puberty
GOC:dph
reproductive developmental process
GOC:dph
GOC:tb
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
organ system process
biological_process
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
GOC:mtg_cardio
A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.
Wikipedia:Circulatory_system
biological_process
circulatory system process
A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.
GOC:mtg_cardio
Interacting selectively and non-covalently with any nucleic acid.
GO:0000496
base pairing
molecular_function
nucleic acid binding
Interacting selectively and non-covalently with any nucleic acid.
GOC:jl
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0043566
plasmid binding
molecular_function
microtubule/chromatin interaction
structure specific DNA binding
structure-specific DNA binding
DNA binding
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GOC:dph
GOC:jl
GOC:tb
GOC:vw
Interacting selectively and non-covalently with double-stranded DNA.
dsDNA binding
molecular_function
double-stranded DNA binding
Interacting selectively and non-covalently with double-stranded DNA.
GOC:elh
GOC:vw
dsDNA binding
GOC:elh
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
https://github.com/geneontology/go-ontology/issues/15704
https://github.com/geneontology/go-ontology/issues/16534
kchris
2010-10-21T04:37:54Z
GO:0000130
GO:0001071
GO:0001130
GO:0001131
GO:0001151
GO:0001199
GO:0001204
nucleic acid binding transcription factor activity
transcription factor activity
DNA binding transcription factor activity
gene-specific transcription factor activity
sequence-specific DNA binding transcription factor activity
bacterial-type DNA binding transcription factor activity
bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity
bacterial-type RNA polymerase transcription enhancer sequence-specific DNA binding transcription factor activity
bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding
metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity
metal ion regulated sequence-specific DNA binding transcription factor activity
sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity
transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding
transcription factor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding
transcription factor activity, bacterial-type RNA polymerase transcription enhancer sequence-specific binding
transcription factor activity, metal ion regulated sequence-specific DNA binding
molecular_function
Curator guidance: Note that most DNA-binding transcription factors do not have enzymatic activity. The presence of specific domains known to be present in DNA-binding transcription factors (HOX, GATA etc) should be used to help decide whether a protein is a DNA binding transcription factor or a coregulator. If a protein has an enzymatic activity (for example, ubiquitin ligase, histone acetyl transferase) and no known DNA binding domain, consider annotating to GO:0003712 transcription coregulator activity. Special care should be taken with proteins containing Myb/SANT and ARID domains, since only a subset of proteins containing these domains are DNA-binding transcription factors for specific genes.
DNA-binding transcription factor activity
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
GOC:txnOH-2018
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
GO:0000498
GO:0044822
Reactome:R-HSA-203922
base pairing with RNA
molecular_function
poly(A) RNA binding
poly(A)-RNA binding
poly-A RNA binding
RNA binding
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
GOC:jl
GOC:mah
Reactome:R-HSA-203922
Exportin-5 recognizes 3' overhang of pre-miRNA
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
GO:0000499
base pairing with mRNA
molecular_function
mRNA binding
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
GOC:kmv
GOC:pr
SO:0000234
The action of a molecule that contributes to the structural integrity of the ribosome.
GO:0003736
GO:0003737
GO:0003738
GO:0003739
GO:0003740
GO:0003741
GO:0003742
ribosomal protein
molecular_function
ribosomal RNA
Note that this term may be used to annotate ribosomal RNAs as well as ribosomal proteins.
structural constituent of ribosome
The action of a molecule that contributes to the structural integrity of the ribosome.
GOC:mah
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
Wikipedia:Enzyme
enzyme activity
molecular_function
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GOC:vw
ISBN:0198506732
enzyme activity
GOC:dph
GOC:tb
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
https://github.com/geneontology/go-ontology/issues/19078
dph
2015-11-11T12:47:56Z
GO:0061745
hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement
RHEA:19669
Reactome:R-HSA-1445143
Reactome:R-HSA-1458485
Reactome:R-HSA-156923
Reactome:R-HSA-164381
Reactome:R-HSA-165055
Reactome:R-HSA-167415
Reactome:R-HSA-170666
Reactome:R-HSA-170685
Reactome:R-HSA-170686
Reactome:R-HSA-177501
Reactome:R-HSA-203973
Reactome:R-HSA-2130641
Reactome:R-HSA-2130725
Reactome:R-HSA-2584246
Reactome:R-HSA-380979
Reactome:R-HSA-392133
Reactome:R-HSA-392212
Reactome:R-HSA-418574
Reactome:R-HSA-418582
Reactome:R-HSA-421835
Reactome:R-HSA-428941
Reactome:R-HSA-432707
Reactome:R-HSA-5333615
Reactome:R-HSA-5389839
Reactome:R-HSA-5389842
Reactome:R-HSA-5419273
Reactome:R-HSA-5419279
Reactome:R-HSA-555065
Reactome:R-HSA-5623513
Reactome:R-HSA-5638006
Reactome:R-HSA-5658231
Reactome:R-HSA-5665809
Reactome:R-HSA-5672017
Reactome:R-HSA-5694527
Reactome:R-HSA-6807877
Reactome:R-HSA-6814833
Reactome:R-HSA-8847534
Reactome:R-HSA-8847883
Reactome:R-HSA-8849082
Reactome:R-HSA-8854173
Reactome:R-HSA-8854255
Reactome:R-HSA-8854329
Reactome:R-HSA-8854604
Reactome:R-HSA-8854612
Reactome:R-HSA-8868661
Reactome:R-HSA-8981353
Reactome:R-HSA-8982020
Reactome:R-HSA-8982021
Reactome:R-HSA-8982025
Reactome:R-HSA-983422
ARF small monomeric GTPase activity
RHEB small monomeric GTPase activity
Rab small monomeric GTPase activity
Ran small monomeric GTPase activity
Ras small monomeric GTPase activity
Rho small monomeric GTPase activity
Sar small monomeric GTPase activity
dynamin GTPase activity
heterotrimeric G-protein GTPase activity
protein-synthesizing GTPase activity
protein-synthesizing GTPase activity, elongation
protein-synthesizing GTPase activity, initiation
protein-synthesizing GTPase activity, termination
signal-recognition-particle GTPase activity
small monomeric GTPase activity
tubulin GTPase activity
molecular_function
GTPase activity, coupled
heterotrimeric G-protein GTPase, alpha-subunit
heterotrimeric G-protein GTPase, beta-subunit
heterotrimeric G-protein GTPase, gamma-subunit
GTPase activity
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
ISBN:0198547684
PMID:26832457
PMID:27218782
Reactome:R-HSA-1445143
RAB8A,10,13,14 hydrolyze GTP
Reactome:R-HSA-1458485
RALA hydrolyzes GTP
Reactome:R-HSA-156923
Hydrolysis of eEF1A:GTP
Reactome:R-HSA-164381
G alpha (s) auto-inactivates by hydrolysing GTP to GDP
Reactome:R-HSA-165055
Hydrolysis of Ran:GTP to Ran:GDP
Reactome:R-HSA-167415
G-protein alpha subunit is inactivated
Reactome:R-HSA-170666
Adenylate cyclase increases the GTPase activity of G alpha-olf
Reactome:R-HSA-170685
Adenylaye cyclase increases the GTPase activity of G alpha-olf
Reactome:R-HSA-170686
Adenylate cyclase increases the GTPase activity of Gi alpha
Reactome:R-HSA-177501
Endocytosis (internalization) of clathrin-coated vesicle
Reactome:R-HSA-203973
Vesicle budding
Reactome:R-HSA-2130641
Translocation of TGN-lysosome vesicle to lysosome
Reactome:R-HSA-2130725
Internalization of MHC II:Ii clathrin coated vesicle
Reactome:R-HSA-2584246
GNAT1-GTP hydrolyses its bound GTP to GDP
Reactome:R-HSA-380979
RHEB in mTORC1:RHEB:GTP hydrolyses GTP
Reactome:R-HSA-392133
G alpha (z) auto-inactivates by hydrolysing GTP to GDP
Reactome:R-HSA-392212
G alpha (i) auto-inactivates by hydrolysing GTP to GDP
Reactome:R-HSA-418574
G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP
Reactome:R-HSA-418582
G alpha (q) auto-inactivates by hydrolysing GTP to GDP
Reactome:R-HSA-421835
trans-Golgi Network Vesicle Scission
Reactome:R-HSA-428941
P2Y purinoceptor 1 activates MAP kinase p38 alpha
Reactome:R-HSA-432707
trans-Golgi Network Lysosomal Vesicle Scission
Reactome:R-HSA-5333615
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC
Reactome:R-HSA-5389839
39S subunit binds 28S subunit:mRNA:fMet-tRNA
Reactome:R-HSA-5389842
TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome
Reactome:R-HSA-5419273
Hydrolysis of GTP and dissociation of 28S and 39S subunits
Reactome:R-HSA-5419279
Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA)
Reactome:R-HSA-555065
Formation of clathrin coated vesicle
Reactome:R-HSA-5623513
ASAP1 stimulates GTPase activity of ARF4
Reactome:R-HSA-5638006
ARL3 hydrolyzes GTP
Reactome:R-HSA-5658231
RAS GAPs stimulate RAS GTPase activity
Reactome:R-HSA-5665809
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments
Reactome:R-HSA-5672017
Rheb in the mTORC1 complex hydrolyses GTP
Reactome:R-HSA-5694527
Loss of SAR1B GTPase
Reactome:R-HSA-6807877
ARFGAPs stimulate ARF GTPase activity
Reactome:R-HSA-6814833
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP
Reactome:R-HSA-8847534
RAB43 hydrolyses GTP
Reactome:R-HSA-8847883
CYTH proteins stimulate ARF1 GTPase activity
Reactome:R-HSA-8849082
ARHGAP35 stimulates RHOA GTPase activity
Reactome:R-HSA-8854173
TBC RabGAPs accelerate GTP hydrolysis by RAB35
Reactome:R-HSA-8854255
TBC1D2A accelerates GTP hydrolysis by RAB7
Reactome:R-HSA-8854329
TBC1D15 accelerates GTP hydrolysis by RAB7
Reactome:R-HSA-8854604
TBC1D16 accelerates GTP hydrolysis by RAB4A
Reactome:R-HSA-8854612
TBC1D25 accelerates GTP hydrolysis by RAB33B
Reactome:R-HSA-8868661
Dynamin-mediated GTP hydrolysis promotes vesicle scission
Reactome:R-HSA-8981353
RASA1 stimulates RAS GTPase activity
Reactome:R-HSA-8982020
G alpha (i)i1/i2/i3 in G (i):RGS complex is inactivated
Reactome:R-HSA-8982021
G alpha (z) in G alpha (z):RGS complex is inactivated
Reactome:R-HSA-8982025
G alpha (q) in G (q):RGS complex is inactivated
Reactome:R-HSA-983422
Disassembly of COPII coated vesicle
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
GO:0016809
MetaCyc:RXN0-5195
Reactome:R-HSA-1168640
Reactome:R-HSA-1234159
Reactome:R-HSA-1236935
Reactome:R-HSA-1236970
Reactome:R-HSA-1251997
Reactome:R-HSA-1433374
Reactome:R-HSA-1504193
Reactome:R-HSA-174058
Reactome:R-HSA-174105
Reactome:R-HSA-174202
Reactome:R-HSA-174203
Reactome:R-HSA-174255
Reactome:R-HSA-180573
Reactome:R-HSA-180603
Reactome:R-HSA-187574
Reactome:R-HSA-188191
Reactome:R-HSA-193682
Reactome:R-HSA-209061
Reactome:R-HSA-211715
Reactome:R-HSA-2130282
Reactome:R-HSA-2213200
Reactome:R-HSA-264458
Reactome:R-HSA-353125
Reactome:R-HSA-3640874
Reactome:R-HSA-3928656
Reactome:R-HSA-450466
Reactome:R-HSA-4608855
Reactome:R-HSA-4641256
Reactome:R-HSA-4641260
Reactome:R-HSA-5358340
Reactome:R-HSA-5358460
Reactome:R-HSA-5362448
Reactome:R-HSA-5387392
Reactome:R-HSA-5607724
Reactome:R-HSA-5607731
Reactome:R-HSA-5610754
Reactome:R-HSA-5610757
Reactome:R-HSA-5610758
Reactome:R-HSA-5610760
Reactome:R-HSA-5635854
Reactome:R-HSA-5635868
Reactome:R-HSA-5658430
Reactome:R-HSA-5668481
Reactome:R-HSA-5668520
Reactome:R-HSA-5687112
Reactome:R-HSA-5693081
Reactome:R-HSA-6784628
Reactome:R-HSA-6784676
Reactome:R-HSA-68825
Reactome:R-HSA-68948
Reactome:R-HSA-69016
Reactome:R-HSA-69600
Reactome:R-HSA-74730
Reactome:R-HSA-75825
Reactome:R-HSA-8849797
Reactome:R-HSA-8850992
Reactome:R-HSA-8852354
Reactome:R-HSA-8854044
Reactome:R-HSA-8854071
Reactome:R-HSA-8866553
Reactome:R-HSA-8866858
Reactome:R-HSA-8934819
Reactome:R-HSA-8939801
Reactome:R-HSA-8952408
Reactome:R-HSA-8957265
Reactome:R-HSA-9008110
Reactome:R-HSA-9008475
Reactome:R-HSA-9009362
Reactome:R-HSA-9010096
Reactome:R-HSA-9011313
Reactome:R-HSA-9604642
Reactome:R-HSA-983150
Reactome:R-HSA-983158
endoprotease activity
proteasome endopeptidase activity
proteinase
molecular_function
elastase activity
endopeptidase activity
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE
Reactome:R-HSA-1168640
Ubiquitinated IkB is degraded
Reactome:R-HSA-1234159
Proteasome proteolyzes ub-HIF-alpha
Reactome:R-HSA-1236935
Proteasomal cleavage of substrate
Reactome:R-HSA-1236970
Proteasomal clevage of exogenous antigen
Reactome:R-HSA-1251997
Cleavage of ERBB4m80 by gamma-scretase complex
Reactome:R-HSA-1433374
Processing of SCF isoform 1
Reactome:R-HSA-1504193
Ubiquitinated DVL is degraded by the proteasome
Reactome:R-HSA-174058
Degradation of multiubiquitinated Cdh1
Reactome:R-HSA-174105
Degradation of multiubiquitinated cell cycle proteins
Reactome:R-HSA-174202
Degradation of multiubiquitinated Securin
Reactome:R-HSA-174203
SCF-mediated degradation of Emi1
Reactome:R-HSA-174255
Degradation multiubiquitinated Cyclin A
Reactome:R-HSA-180573
Degradation of ubiquitinated CD4
Reactome:R-HSA-180603
Proteosome-mediated degradation of APOBEC3G
Reactome:R-HSA-187574
Degradation of ubiquitinated p27/p21 by the 26S proteasome
Reactome:R-HSA-188191
APC/C:Cdh1-mediated degradation of Skp2
Reactome:R-HSA-193682
gamma-secretase cleaves the p75NTR transmembrane domain
Reactome:R-HSA-209061
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex
Reactome:R-HSA-211715
Proteasome mediated degradation of PAK-2p34
Reactome:R-HSA-2130282
Degradation of ubiquitinated beta catenin by the proteasome
Reactome:R-HSA-2213200
Release of endostatin-like peptides
Reactome:R-HSA-264458
Proteasome mediated degradation of COP1
Reactome:R-HSA-353125
26S proteosome degrades ODC holoenzyme complex
Reactome:R-HSA-3640874
Ub-RibC-AXIN is degraded by the proteasome
Reactome:R-HSA-3928656
gamma-secretase cleaves EPHB2
Reactome:R-HSA-450466
AUF1:mRNA complex is destroyed
Reactome:R-HSA-4608855
PRICKLE1 is degraded by the proteasome
Reactome:R-HSA-4641256
Ubiquitinated AXIN is degraded by the proteasome
Reactome:R-HSA-4641260
Ubiquitinated DVL1 is degraded by the proteasome
Reactome:R-HSA-5358340
Autoproteolytic cleavage of Hh precursors
Reactome:R-HSA-5358460
HPE SHH variants don't undergo autoproteolytic cleavage
Reactome:R-HSA-5362448
Hh C-terminal fragments are degraded by the proteasome
Reactome:R-HSA-5387392
processing defective Hh variants are degraded by the proteasome
Reactome:R-HSA-5607724
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex
Reactome:R-HSA-5607731
26S proteasome processes p-7S-p100:RELB to form p52:RELB
Reactome:R-HSA-5610754
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor
Reactome:R-HSA-5610757
GLI2 is degraded by the proteasome
Reactome:R-HSA-5610758
GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP
Reactome:R-HSA-5610760
GLI1 is degraded by the proteasome after ubiquitination by ITCH
Reactome:R-HSA-5635854
GLI2,3 are degraded by the proteasome
Reactome:R-HSA-5635868
ub-GLI is degraded by the proteasome
Reactome:R-HSA-5658430
NF1 is degraded by the proteasome
Reactome:R-HSA-5668481
Protesomal degradation of K48polyUb-TRAF3
Reactome:R-HSA-5668520
26Sproteasome degrades K48polyUb-NIK
Reactome:R-HSA-5687112
MAPK6 is degraded by the 26S proteasome
Reactome:R-HSA-5693081
FURIN cleaves 7K-BACE1 to 7K-BACE1(46-501)
Reactome:R-HSA-6784628
PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer
Reactome:R-HSA-6784676
PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer
Reactome:R-HSA-68825
Ubiquitinated geminin is degraded by the proteasome
Reactome:R-HSA-68948
Ubiquitinated Orc1 is degraded by the proteasome
Reactome:R-HSA-69016
Ubiquitinated Cdc6 is degraded by the proteasome
Reactome:R-HSA-69600
Proteolytic degradation of ubiquitinated-Cdc25A
Reactome:R-HSA-74730
Insulin degradation
Reactome:R-HSA-75825
Proteasome mediated degradation of Cyclin D1
Reactome:R-HSA-8849797
Membrane proteases cleave Profilaggrin producing Filaggrin
Reactome:R-HSA-8850992
Proteasome degrades polyubiquitinated PTEN
Reactome:R-HSA-8852354
GTSE1 facilitates proteasome-mediated degradation of TP53
Reactome:R-HSA-8854044
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7
Reactome:R-HSA-8854071
Proteasome-mediated degradation of PolyUb-FBXL7
Reactome:R-HSA-8866553
misfolded CFTR is degraded by the 26S proteasome
Reactome:R-HSA-8866858
CFTR F508del is degraded by the 26S proteasome
Reactome:R-HSA-8934819
Cytoplasmic proteases cleave Profilaggrin producing Filaggrin
Reactome:R-HSA-8939801
26S proteasome degrades PolyUb-RUNX2
Reactome:R-HSA-8952408
Polyubiquitinated RUNX3 is degraded by the proteasome
Reactome:R-HSA-8957265
26S proteasome degrades TP73 polyubiquitinated by ITCH
Reactome:R-HSA-9008110
Proteasome degrades polyubiquitinated RUNX2
Reactome:R-HSA-9008475
Proteasome degrades polyubiquitinated RUNX2
Reactome:R-HSA-9009362
Proteasome degrades PolyUb-RUNX2
Reactome:R-HSA-9010096
Gamma-secretase cleaves APP(672-770) to APP(672-711) and APP(672-713)
Reactome:R-HSA-9011313
Proteasome degrades ubiquitinated ROBO3.1
Reactome:R-HSA-9604642
Proteasome degrades ubiquitinated NICD4
Reactome:R-HSA-983150
Proteasomal cleavage of substrate
Reactome:R-HSA-983158
Trimming of peptides in ER
elastase activity
GOC:krc
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
GO:0008026
Reactome:R-HSA-167097
Reactome:R-HSA-169461
Reactome:R-HSA-169468
Reactome:R-HSA-5690996
Reactome:R-HSA-75949
Reactome:R-HSA-9613490
Reactome:R-HSA-9613494
Reactome:R-HSA-9613497
Reactome:R-HSA-9613498
ATP-dependent helicase activity
molecular_function
Note that most helicases catalyze processive duplex unwinding.
helicase activity
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
GOC:jl
Reactome:R-HSA-167097
HIV Promoter Opening: First Transition
Reactome:R-HSA-169461
MCM8 mediated fork unwinding
Reactome:R-HSA-169468
MCM2-7 mediated fork unwinding
Reactome:R-HSA-5690996
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA
Reactome:R-HSA-75949
RNA Polymerase II Promoter Opening: First Transition
Reactome:R-HSA-9613490
Unwinding of DNA for the nascent HIV-1 transcript: Second Transition
Reactome:R-HSA-9613494
Unwinding of DNA for the Nascent Transcript: Second Transition
Reactome:R-HSA-9613497
Unwinding DNA for the nascent transcript
Reactome:R-HSA-9613498
Unwinding of DNA for the nascent HIV-1 transcript
Catalysis of the hydrolysis of ester linkages within nucleic acids.
molecular_function
Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', and 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' do not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.
nuclease activity
Catalysis of the hydrolysis of ester linkages within nucleic acids.
ISBN:0198547684
Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
GO:0004537
Reactome:R-HSA-211247
Reactome:R-HSA-5685994
Reactome:R-HSA-6785986
caspase-activated deoxyribonuclease activity
molecular_function
deoxyribonuclease activity
Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
GOC:mah
ISBN:0198547684
Reactome:R-HSA-211247
Cleavage of DNA by DFF40
Reactome:R-HSA-5685994
Long-range resection of DNA DSBs by EXO1 or DNA2
Reactome:R-HSA-6785986
DNA nucleases unhook the interstrand crosslink (ICL)
Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.
https://github.com/geneontology/go-ontology/issues/14336
GO:0008262
NES receptor
importin-alpha export receptor activity
molecular_function
exportin activity
importin-alpha binding
nuclear export signal receptor activity
Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.
GOC:bf
GOC:mah
GOC:pg
GOC:vw
PMID:11743003
PMID:25802992
PMID:28713609
Wikipedia:Nuclear_transport
importin-alpha export receptor activity
GO:0008262
The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
molecular_function
structural molecule activity
The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
GOC:mah
GOC:vw
The action of a molecule that contributes to the structural integrity of a cell wall.
molecular_function
structural constituent of cell wall
The action of a molecule that contributes to the structural integrity of a cell wall.
GOC:mah
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
molecular_function
structural constituent of cytoskeleton
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
GOC:mah
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
core extracellular matrix
core matrisome
extracellular matrix glycoprotein
molecular_function
Extracellular matrix glycoproteins may be annotated to this term. PMID:24443019
extracellular matrix structural constituent
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
GOC:mah
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0005478
EC:7
Reactome:R-HSA-168313
Reactome:R-HSA-178215
molecular_function
carrier
Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GOC:ai
GOC:dgf
Reactome:R-HSA-168313
Virion-associated M2 protein mediated ion infusion
Reactome:R-HSA-178215
SMAD7:SMURF1 complex is exported to the cytosol
Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
GO:0005279
amine/amide/polyamine channel activity
amine/polyamine transmembrane transporter activity
amino acid-polyamine transmembrane transporter activity
molecular_function
amine transmembrane transporter activity
Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
GOC:mtg_transport
ISBN:0198506732
ISBN:0815340729
Enables the directed movement of lipids into, out of or within a cell, or between cells.
Reactome:R-HSA-1369028
Reactome:R-HSA-1369052
Reactome:R-HSA-174786
Reactome:R-HSA-5682285
Reactome:R-HSA-5682311
Reactome:R-HSA-5683672
Reactome:R-HSA-5683714
Reactome:R-HSA-5688397
Reactome:R-HSA-6801250
Reactome:R-HSA-8848053
Reactome:R-HSA-8866329
lipophorin
molecular_function
apolipoprotein
lipid transporter activity
GO_REF:0000090
Enables the directed movement of lipids into, out of or within a cell, or between cells.
GOC:ai
Reactome:R-HSA-1369028
ABCAs mediate lipid efflux
Reactome:R-HSA-1369052
ABCAs mediate lipid influx
Reactome:R-HSA-174786
ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex
Reactome:R-HSA-5682285
ABCA12 transports lipids from cytosol to extracellular region
Reactome:R-HSA-5682311
Defective ABCA12 does not transport lipids from cytosol to extracellular region
Reactome:R-HSA-5683672
Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body
Reactome:R-HSA-5683714
ABCA3 transports PC, PG from ER membrane to lamellar body
Reactome:R-HSA-5688397
Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body
Reactome:R-HSA-6801250
TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane
Reactome:R-HSA-8848053
ABCA5 transports CHOL from lysosomal lumen to cytosol
Reactome:R-HSA-8866329
MTTP lipidates APOB-100, forming a pre-VLDL
Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage.
molecular_function
organic acid transmembrane transporter activity
Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage.
ISBN:0198506732
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
Wikipedia:Binding_(molecular)
ligand
molecular_function
Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children.
binding
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GOC:ceb
GOC:mah
ISBN:0198506732
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0001948
GO:0045308
Reactome:R-HSA-170835
Reactome:R-HSA-170846
protein amino acid binding
glycoprotein binding
molecular_function
protein binding
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GOC:go_curators
Reactome:R-HSA-170835
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3
Reactome:R-HSA-170846
TGFBR2 recruits TGFBR1
A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).
GO:0008372
NIF_Subcellular:sao1337158144
cell or subcellular entity
cellular component
cellular_component
subcellular entity
Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.
cellular_component
A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).
GOC:pdt
NIF_Subcellular:sao1337158144
subcellular entity
NIF_Subcellular:nlx_subcell_100315
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
Wikipedia:Extracellular
extracellular
cellular_component
Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
GOC:go_curators
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
NIF_Subcellular:sao1425028079
cellular_component
intercellular space
Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term.
extracellular space
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
ISBN:0198547684
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
Wikipedia:Cell_wall
cellular_component
cell wall
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
GOC:giardia
ISBN:0198547684
PMID:15134259
Wikipedia:Microbial_cyst
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
Wikipedia:Intracellular
internal to cell
protoplasm
cellular_component
nucleocytoplasm
protoplast
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
ISBN:0198506732
nucleocytoplasm
GOC:mah
protoplast
GOC:mah
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
GO:0005636
Wikipedia:Nuclear_envelope
cellular_component
nuclear envelope
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
ISBN:0198547684
That part of the nuclear content other than the chromosomes or the nucleolus.
NIF_Subcellular:sao661522542
Wikipedia:Nucleoplasm
cellular_component
nucleoplasm
That part of the nuclear content other than the chromosomes or the nucleolus.
GOC:ma
ISBN:0124325653
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
janelomax
2013-08-28T12:11:37Z
GO:0044797
GO:0044798
cellular_component
cytoplasmic transcription factor complex
nuclear transcription factor complex
transcription factor complex
transcription regulator complex
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
GOC:jl
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
Wikipedia:Chromosome
interphase chromosome
prophase chromosome
cellular_component
chromatid
Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.
chromosome
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
ISBN:0198547684
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
NIF_Subcellular:sao1820400233
Wikipedia:Nucleolus
cellular_component
nucleolus
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
ISBN:0198506732
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
Wikipedia:Cytoplasm
cellular_component
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
ISBN:0198547684
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
NIF_Subcellular:sao1860313010
Wikipedia:Mitochondrion
mitochondria
cellular_component
Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products located in these mitochondrial relics in species such as Entamoeba histolytica, Giardia intestinalis or others, please use GO:0032047 'mitosome' or GO:0042566 'hydrogenosome'. (See PMID:24316280 for a list of species currently known to contain mitochondrion-related organelles.)
mitochondrion
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
GOC:giardia
ISBN:0198506732
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
GO:0031980
NIF_Subcellular:sao1804523077
Wikipedia:Mitochondrial_matrix
mitochondrial lumen
mitochondrial stroma
cellular_component
mitochondrial matrix
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
GOC:as
ISBN:0198506732
A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.
55S ribosome, mitochondrial
cellular_component
mitochondrial ribosome
A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.
GOC:mah
ISBN:0198506732
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
NIF_Subcellular:sao585356902
Wikipedia:Lysosome
cellular_component
lysosome
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
GOC:mah
ISBN:0198506732
A vacuole to which materials ingested by endocytosis are delivered.
NIF_Subcellular:sao1720343330
Wikipedia:Endosome
cellular_component
endosome
A vacuole to which materials ingested by endocytosis are delivered.
ISBN:0198506732
PMID:19696797
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
Wikipedia:Vacuole
cellular_component
vacuolar carboxypeptidase Y
vacuole
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
GOC:mtg_sensu
ISBN:0198506732
The volume enclosed within the vacuolar membrane.
cellular_component
vacuolar lumen
The volume enclosed within the vacuolar membrane.
ISBN:0198506732
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
GO:0019818
peroxisome vesicle
NIF_Subcellular:sao499555322
Wikipedia:Peroxisome
cellular_component
peroxisomal
peroxisome
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
GOC:pm
PMID:9302272
UniProtKB-KW:KW-0576
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
NIF_Subcellular:sao1036339110
Wikipedia:Endoplasmic_reticulum
ER
cellular_component
endoplasmic reticulum
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
ISBN:0198506732
The volume enclosed by the membranes of the endoplasmic reticulum.
GO:0016022
ER cisterna
ER lumen
cisternal lumen
endoplasmic reticulum cisterna
cellular_component
endoplasmic reticulum lumen
The volume enclosed by the membranes of the endoplasmic reticulum.
ISBN:0198547684
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
Golgi
NIF_Subcellular:sao451912436
Wikipedia:Golgi_apparatus
Golgi complex
Golgi ribbon
cellular_component
Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon.
Golgi apparatus
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
ISBN:0198506732
Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.
NIF_Subcellular:sao819927218
cellular_component
Golgi vesicle
vesicular component
Note that this definition includes vesicles that are transiently associated with the Golgi.
Golgi-associated vesicle
Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.
GOC:mah
vesicular component
NIF_Subcellular:sao138219748
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
adiposome
lipid body
lipid particle
cellular_component
Note that this term does not refer to vesicles, but instead to structures in which lipids do not necessarily form bilayers.
lipid droplet
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
GOC:mah
GOC:tb
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
Wikipedia:Microtubule_organizing_center
MTOC
microtubule organising centre
cellular_component
microtubule organizing center
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
GOC:vw
ISBN:0815316194
PMID:17072892
PMID:17245416
Wikipedia:Microtubule_organizing_center
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
NIF_Subcellular:sao101633890
Wikipedia:Cytosol
cellular_component
cytosol
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GOC:hjd
GOC:jl
An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
GO:0033279
NIF_Subcellular:sao1429207766
Wikipedia:Ribosome
free ribosome
membrane bound ribosome
cellular_component
ribosomal RNA
ribosome
An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
ISBN:0198506732
free ribosome
NIF_Subcellular:sao1139385046
membrane bound ribosome
NIF_Subcellular:sao1291545653
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
Wikipedia:Cytoskeleton
cellular_component
cytoskeleton
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
GOC:mah
ISBN:0198547684
PMID:16959967
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
NIF_Subcellular:sao1846835077
Wikipedia:Microtubule
microtubuli
microtubulus
neurotubule
cellular_component
microtubule
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
ISBN:0879693568
neurotubule
NIF_Subcellular:sao248349196
A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.
cellular_component
axonemal microtubule
A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.
GOC:cilia
ISBN:0815316194
Any microtubule in the nucleus of a cell.
cellular_component
nuclear microtubule
Any microtubule in the nucleus of a cell.
GOC:mah
Any microtubule in the cytoplasm of a cell.
non-spindle-associated astral microtubule
cellular_component
cytoplasmic microtubule
Any microtubule in the cytoplasm of a cell.
GOC:mah
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0005904
juxtamembrane
NIF_Subcellular:sao1663586795
Wikipedia:Cell_membrane
cell membrane
cellular membrane
cytoplasmic membrane
plasmalemma
bacterial inner membrane
inner endospore membrane
plasma membrane lipid bilayer
cellular_component
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
ISBN:0716731363
cellular membrane
NIF_Subcellular:sao6433132645
plasma membrane lipid bilayer
GOC:mah
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
integral to plasma membrane
cellular_component
integral component of plasma membrane
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GOC:dos
GOC:go_curators
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
GO:0072372
FMA:67181
NIF_Subcellular:sao787716553
Wikipedia:Cilium
eukaryotic flagellum
microtubule-based flagellum
primary cilium
cellular_component
flagellum
Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms.
cilium
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
GOC:cilia
GOC:curators
GOC:kmv
GOC:vw
ISBN:0198547684
PMID:16824949
PMID:17009929
PMID:20144998
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
GO:0035085
GO:0035086
Wikipedia:Axoneme
ciliary axoneme
cilium axoneme
flagellar axoneme
flagellum axoneme
cellular_component
Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.
axoneme
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
GOC:bf
GOC:cilia
ISBN:0198547684
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
Wikipedia:Cell_cortex
cellular_component
cell periphery
peripheral cytoplasm
cell cortex
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
GOC:mah
ISBN:0815316194
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
janelomax
2012-10-23T15:40:34Z
GO:0044261
GO:0044723
Wikipedia:Carbohydrate_metabolism
carbohydrate metabolism
multicellular organismal carbohydrate metabolic process
biological_process
single-organism carbohydrate metabolic process
carbohydrate metabolic process
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
GOC:mah
ISBN:0198506732
The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
organic acid metabolism
biological_process
organic acid metabolic process
The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
energy pathways
biological_process
intermediary metabolism
metabolic energy generation
generation of precursor metabolites and energy
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
GOC:jl
intermediary metabolism
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
regulation of carbohydrate metabolism
biological_process
regulation of carbohydrate metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
GOC:go_curators
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0055134
cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
biological_process
nucleobase, nucleoside and nucleotide metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase-containing compound metabolic process
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:ai
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GOC:dph
GOC:tb
Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0055132
DNA metabolism
cellular DNA metabolism
biological_process
DNA metabolic process
Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
ISBN:0198506732
The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
DNA breakdown
DNA catabolism
DNA degradation
biological_process
DNA catabolic process
The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
GOC:go_curators
ISBN:0198506732
The cellular synthesis of RNA on a template of DNA.
GO:0006350
GO:0061018
GO:0061022
cellular transcription
transcription
Wikipedia:Transcription_(genetics)
DNA-dependent transcription
cellular transcription, DNA-dependent
transcription, DNA-dependent
biological_process
transcription regulator activity
transcription, DNA-templated
The cellular synthesis of RNA on a template of DNA.
GOC:jl
GOC:txnOH
transcription, DNA-dependent
GOC:txnOH
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0032583
GO:0045449
GO:0061019
transcriptional control
regulation of cellular transcription, DNA-dependent
regulation of transcription, DNA-dependent
biological_process
regulation of gene-specific transcription
regulation of transcription, DNA-templated
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GOC:go_curators
GOC:txnOH
regulation of transcription, DNA-dependent
GOC:txnOH
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
GO:0006365
35S primary transcript processing
biological_process
rRNA processing
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
GOC:curators
Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
biological_process
cleavage stimulation factor activity
mRNA cleavage
Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
GOC:mah
The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
https://github.com/geneontology/go-ontology/issues/14854
transcription from mitochondrial promoter
biological_process
mitochondrial transcription
The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
GOC:jl
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
GO:0006394
Wikipedia:Post-transcriptional_modification
biological_process
RNA processing
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
GOC:mah
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
biological_process
mRNA maturation
mRNA processing
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
GOC:mah
The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established.
tRNA metabolism
biological_process
tRNA metabolic process
The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established.
ISBN:0198506732
The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
RNA breakdown
RNA catabolism
RNA degradation
biological_process
RNA catabolic process
The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
ISBN:0198506732
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
mRNA breakdown
mRNA catabolism
mRNA degradation
biological_process
mRNA decay
mRNA catabolic process
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
ISBN:0198506732
mRNA decay
GOC:ascb_2010
GOC:dph
GOC:tb
A process in which RNA is transported to, or maintained in, a specific location.
RNA localisation
establishment and maintenance of RNA localization
biological_process
RNA localization
A process in which RNA is transported to, or maintained in, a specific location.
GOC:ai
RNA localisation
GOC:mah
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
GO:0006416
GO:0006453
GO:0043037
Wikipedia:Translation_(genetics)
protein anabolism
protein biosynthesis
protein biosynthetic process
protein formation
protein synthesis
protein translation
biological_process
translation
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
GOC:go_curators
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
GO:0006440
GO:0006454
biopolymerisation
biopolymerization
protein synthesis initiation
translation initiation
biological_process
translational initiation
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
ISBN:019879276X
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
GO:0006442
GO:0006455
protein synthesis elongation
translation elongation
biological_process
translational elongation
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
GOC:ems
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
GO:0006443
GO:0006456
protein synthesis termination
translation termination
translational complex disassembly
biological_process
translational termination
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
GOC:hjd
ISBN:019879276X
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
GO:0006445
regulation of protein anabolism
regulation of protein biosynthesis
regulation of protein formation
regulation of protein synthesis
biological_process
regulation of translation
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
GOC:isa_complete
Any process that modulates the frequency, rate or extent of translational initiation.
biological_process
regulation of translational initiation
Any process that modulates the frequency, rate or extent of translational initiation.
GOC:go_curators
Any process that modulates the frequency, rate, extent or accuracy of translational elongation.
biological_process
regulation of translational elongation
Any process that modulates the frequency, rate, extent or accuracy of translational elongation.
GOC:go_curators
Any process that modulates the frequency, rate or extent of translational termination.
biological_process
regulation of translational termination
Any process that modulates the frequency, rate or extent of translational termination.
GOC:go_curators
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
GO:0007022
GO:0007024
GO:0007025
Wikipedia:Protein_folding
alpha-tubulin folding
beta-tubulin folding
chaperonin-mediated tubulin folding
biological_process
chaperone activity
chaperonin ATPase activity
co-chaperone activity
co-chaperonin activity
glycoprotein-specific chaperone activity
non-chaperonin molecular chaperone ATPase activity
protein complex assembly, multichaperone pathway
protein folding
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
GOC:go_curators
GOC:rb
alpha-tubulin folding
GOC:mah
beta-tubulin folding
GOC:mah
chaperonin-mediated tubulin folding
GOC:mah
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
protein modification process
biological_process
process resulting in protein modification
protein tagging activity
cellular protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GOC:go_curators
protein modification process
GOC:bf
GOC:jl
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
Wikipedia:Proteolysis
peptidolysis
ATP-dependent proteolysis
biological_process
This term was intentionally placed under 'protein metabolic process ; GO:0019538' rather than 'protein catabolic process ; GO:0030163' to cover all processes centered on breaking peptide bonds, including those involved in protein processing.
proteolysis
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GOC:bf
GOC:mah
ATP-dependent proteolysis
GOC:mah
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
GO:0006519
amino acid and derivative metabolism
amino acid metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolism
biological_process
cellular amino acid metabolic process
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
ISBN:0198506732
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.
regulation of amino acid metabolism
biological_process
regulation of cellular amino acid metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.
GOC:go_curators
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
Wikipedia:Protein_targeting
protein sorting along secretory pathway
biological_process
nascent polypeptide association
Note that protein targeting encompasses the transport of the protein to the specified location, and may also include additional steps such as protein processing.
protein targeting
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
GOC:ma
The process of directing proteins towards a membrane, usually using signals contained within the protein.
protein membrane targeting
protein-membrane targeting
biological_process
protein targeting to membrane
The process of directing proteins towards a membrane, usually using signals contained within the protein.
GOC:curators
The process of directing proteins towards the lysosome using signals contained within the protein.
protein-lysosome targeting
biological_process
protein targeting to lysosome
The process of directing proteins towards the lysosome using signals contained within the protein.
GOC:curators
The process of directing proteins towards the vacuole, usually using signals contained within the protein.
protein vacuolar targeting
protein-vacuolar targeting
protein-vacuole targeting
vacuolar protein sorting
biological_process
protein targeting to vacuole
The process of directing proteins towards the vacuole, usually using signals contained within the protein.
GOC:curators
vacuolar protein sorting
GOC:vw
The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
protein-peroxisome targeting
biological_process
protein targeting to peroxisome
The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
GOC:ai
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
GO:0043681
protein import into mitochondrion
protein targeting to mitochondria
protein-mitochondrial targeting
biological_process
mitochondrial protein import
mitochondrial translocation
protein targeting to mitochondrion
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
GOC:mcc
ISBN:0716731363
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
Wikipedia:Lipid_metabolism
lipid metabolism
biological_process
lipid metabolic process
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
GOC:ma
The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
Wikipedia:Sulfur_metabolism
sulfur metabolism
sulphur metabolic process
sulphur metabolism
biological_process
sulfur compound metabolic process
The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GOC:ai
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
phosphate metabolism
biological_process
phosphate metabolic process
phosphate-containing compound metabolic process
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GOC:ai
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
nitrogen compound metabolism
biological_process
nitrogen compound metabolic process
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
GOC:jl
ISBN:0198506732
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
janelomax
2012-12-13T16:25:32Z
GO:0015457
GO:0015460
GO:0044765
small molecule transport
solute:solute exchange
biological_process
single-organism transport
Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport.
transport
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
GOC:dos
GOC:dph
GOC:jl
GOC:mah
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
ion transport
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Transport of substances into, out of or within a mitochondrion.
mitochondrial alpha-ketoglutarate/malate transport
mitochondrial aspartate/glutamate transport
mitochondrial sodium/calcium ion exchange
biological_process
mitochondrial transport
Transport of substances into, out of or within a mitochondrion.
GOC:ai
The transport of substances that occurs outside cells.
biological_process
extracellular transport
The transport of substances that occurs outside cells.
GOC:go_curators
The directed extracellular movement of carbohydrates.
biological_process
extracellular carbohydrate transport
The directed extracellular movement of carbohydrates.
GOC:ai
The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
biological_process
lipid transport
The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
ISBN:0198506732
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
GO:0032779
biological_process
copper-induced intracellular protein transport
intracellular protein transport
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
GOC:mah
copper-induced intracellular protein transport
GOC:al
A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
GO:0016194
GO:0016195
Wikipedia:Exocytosis
vesicle exocytosis
biological_process
nonselective vesicle exocytosis
exocytosis
A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
GOC:mah
ISBN:0716731363
PMID:22323285
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
GO:0048221
ER to Golgi transport
ER to Golgi vesicle-mediated transport
anterograde (ER to Golgi) transport
anterograde transport, ER to Golgi
anterograde transport, endoplasmic reticulum to Golgi
anterograde vesicle-mediated transport, ER to Golgi
anterograde vesicle-mediated transport, endoplasmic reticulum to Golgi
endoplasmic reticulum to Golgi transport
endoplasmic reticulum to Golgi vesicle-mediated transport
rough ER to cis-Golgi transport
rough ER to cis-Golgi vesicle-mediated transport
rough endoplasmic reticulum to cis-Golgi transport
rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
biological_process
endoplasmic reticulum to Golgi vesicle-mediated transport
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
GOC:ascb_2009
GOC:dph
GOC:jp
GOC:tb
ISBN:0716731363
The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.
post-Golgi transport
biological_process
post-Golgi vesicle-mediated transport
The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.
GOC:ai
GOC:mah
The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
Golgi to plasma membrane vesicle-mediated transport
biological_process
Golgi to plasma membrane transport
The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
ISBN:0716731363
The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.
GO:0048218
Golgi to endosome vesicle-mediated transport
TGN to endosome transport
trans-Golgi to endosome transport
biological_process
Golgi to endosome transport
The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.
GOC:jl
ISBN:0716731363
PMID:10873832
The directed movement of substances from the Golgi to the vacuole.
Golgi to vacuole vesicle-mediated transport
biological_process
Golgi to vacuole transport
The directed movement of substances from the Golgi to the vacuole.
GOC:ai
The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.
biological_process
vesicle targeting
The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.
GOC:mah
PMID:17335816
Fusion of the membrane of a transport vesicle with its target membrane.
biological_process
vesicle fusion
Fusion of the membrane of a transport vesicle with its target membrane.
GOC:jid
The directed movement of molecules between the nucleus and the cytoplasm.
GO:0000063
nucleocytoplasmic shuttling
biological_process
Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed.
nucleocytoplasmic transport
The directed movement of molecules between the nucleus and the cytoplasm.
GOC:go_curators
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
GO:0016238
Wikipedia:Autophagy_(cellular)
biological_process
autophagy
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
GOC:autophagy
ISBN:0198547684
PMID:11099404
PMID:9412464
The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.
cellular component motion
cellular component movement
biological_process
cell movement
Note that in GO cellular components include whole cells (cell is_a cellular component).
movement of cell or subcellular component
The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.
GOC:dgh
GOC:dph
GOC:jl
GOC:mlg
cellular component motion
GOC:dph
GOC:jl
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
biological_process
response to abiotic stress
response to biotic stress
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to stress
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
jl
2013-12-19T15:25:51Z
GO:1902589
organelle organisation
single organism organelle organization
biological_process
organelle organization and biogenesis
single-organism organelle organization
organelle organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GOC:mah
single organism organelle organization
GOC:TermGenie
organelle organization and biogenesis
GOC:dph
GOC:jl
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
GO:0048287
nuclear organisation
nuclear organization
biological_process
nuclear morphology
nuclear organization and biogenesis
nucleus organization and biogenesis
nucleus organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
GOC:dph
GOC:ems
GOC:jl
GOC:mah
nuclear organization and biogenesis
GOC:mah
nucleus organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.
nuclear envelope organisation
biological_process
nuclear envelope organization and biogenesis
nuclear envelope organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.
GOC:dph
GOC:ems
GOC:jl
GOC:mah
nuclear envelope organisation
GOC:mah
nuclear envelope organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.
nucleolus organisation
biological_process
nucleolus organization and biogenesis
nucleolus organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.
GOC:dph
GOC:jid
GOC:jl
GOC:mah
nucleolus organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
mitochondria organization
mitochondrion organisation
biological_process
mitochondrion organization and biogenesis
mitochondrion organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
GOC:dph
GOC:jl
GOC:mah
GOC:sgd_curators
PMID:9786946
mitochondria organization
GOC:mah
mitochondrion organisation
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
mitochondrial membrane organisation
biological_process
mitochondrial membrane organization and biogenesis
mitochondrial membrane organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
GOC:ai
GOC:dph
GOC:jl
GOC:mah
mitochondrial membrane organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.
plasma membrane organisation
biological_process
plasma membrane organization and biogenesis
plasma membrane organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.
GOC:dph
GOC:jl
GOC:mah
plasma membrane organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
cytoskeleton organisation
biological_process
cytoskeletal organization and biogenesis
cytoskeletal regulator activity
cytoskeleton organization and biogenesis
cytoskeleton organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GOC:dph
GOC:jl
GOC:mah
cytoskeletal organization and biogenesis
GOC:mah
cytoskeleton organization and biogenesis
GOC:mah
Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
biological_process
microtubule-based process
Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
GOC:mah
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
biological_process
microtubule-based movement
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
GOC:cjm
ISBN:0815316194
The removal of tubulin heterodimers from one or both ends of a microtubule.
microtubule disassembly
microtubule shortening
microtubule catastrophe
microtubule depolymerization during nuclear congression
biological_process
microtubule depolymerization
The removal of tubulin heterodimers from one or both ends of a microtubule.
ISBN:0815316194
microtubule catastrophe
GOC:dph
GOC:tb
The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
Wikipedia:Microtubule_nucleation
biological_process
microtubule nucleation
The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
GOC:go_curators
ISBN:0815316194
PMID:12517712
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
down regulation of microtubule depolymerization
down-regulation of microtubule depolymerization
downregulation of microtubule depolymerization
microtubule stabilization
negative regulation of microtubule disassembly
inhibition of microtubule depolymerization
microtubule rescue
negative regulation of microtubule catastrophe
biological_process
negative regulation of microtubule depolymerization
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
GOC:mah
ISBN:0815316194
microtubule rescue
GOC:dph
GOC:tb
negative regulation of microtubule catastrophe
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.
axonemal microtubule stabilization
biological_process
negative regulation of microtubule depolymerization in axoneme
negative regulation of axonemal microtubule depolymerization
Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.
GOC:dph
GOC:mah
negative regulation of microtubule depolymerization in axoneme
GOC:dph
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoplasm organisation
biological_process
cytoplasm organization and biogenesis
cytoplasm organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GOC:curators
GOC:dph
GOC:jl
GOC:mah
cytoplasm organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
ER organisation
endoplasmic reticulum organisation
biological_process
ER organization and biogenesis
endoplasmic reticulum morphology
endoplasmic reticulum organization and biogenesis
endoplasmic reticulum organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
GOC:dph
GOC:jl
GOC:mah
ER organization and biogenesis
GOC:mah
endoplasmic reticulum organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
Golgi organisation
biological_process
Golgi organization and biogenesis
Golgi organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
GOC:dph
GOC:jl
GOC:mah
Golgi organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
peroxisome organisation
biological_process
peroxisome organization and biogenesis
peroxisome-assembly ATPase activity
peroxisome organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
GOC:mah
peroxisome organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
endosome organisation
biological_process
endosome organization and biogenesis
endosome organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
GOC:dph
GOC:jl
GOC:mah
endosome organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
GO:0044086
vacuole organisation
vacuolar assembly
biological_process
vacuole biogenesis
vacuole organization and biogenesis
vacuole organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
GOC:mah
vacuolar assembly
GOC:mah
vacuole biogenesis
GOC:mah
vacuole organization and biogenesis
GOC:mah
The directed movement of substances into, out of or within a vacuole.
biological_process
vacuolar transport
The directed movement of substances into, out of or within a vacuole.
GOC:ai
The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.
biological_process
vacuolar protein breakdown
vacuolar protein catabolic process
vacuolar protein catabolism
vacuolar protein degradation
protein catabolic process in the vacuole
The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.
GOC:mah
GOC:vw
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
lysosome organisation
biological_process
lysosome organization and biogenesis
lysosome organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
GOC:mah
lysosome organization and biogenesis
GOC:mah
The directed movement of substances into, out of or within a lysosome.
biological_process
lysosomal transport
The directed movement of substances into, out of or within a lysosome.
GOC:ai
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
Wikipedia:Cell_cycle
cell-division cycle
biological_process
cell cycle
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
GOC:go_curators
GOC:mtg_cell_cycle
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
Wikipedia:Chromosome_segregation
chromosome division
biological_process
chromosome transmission
chromosome segregation
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
GOC:jl
GOC:mah
GOC:mtg_cell_cycle
GOC:vw
The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs.
mitotic nuclear envelope breakdown
mitotic nuclear envelope catabolism
mitotic nuclear envelope degradation
biological_process
mitotic nuclear envelope disassembly
The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs.
GOC:bf
Any process that modulates the frequency, rate or extent of mitosis.
regulation of mitosis
biological_process
regulation of mitotic nuclear division
Any process that modulates the frequency, rate or extent of mitosis.
GOC:go_curators
The directed movement of the nucleus to a specific location within a cell.
GO:0040023
establishment of position of nucleus
nuclear movement
nuclear positioning
nucleus migration
nucleus positioning
positioning of nucleus
biological_process
establishment of cell nucleus localization
establishment of localization of nucleus
establishment of nucleus localisation
establishment of nucleus localization
nuclear migration
The directed movement of the nucleus to a specific location within a cell.
GOC:ai
establishment of nucleus localisation
GOC:mah
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
Wikipedia:Cell_signaling
biological_process
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GOC:mah
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
davidos
2014-04-15T15:59:10Z
GO:0098602
Wikipedia:Cell_adhesion
biological_process
cell adhesion molecule activity
single organism cell adhesion
cell adhesion
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
GOC:hb
GOC:pf
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
down regulation of cell adhesion
down-regulation of cell adhesion
downregulation of cell adhesion
inhibition of cell adhesion
biological_process
cell adhesion receptor inhibitor activity
negative regulation of cell adhesion
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
GOC:go_curators
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0023033
Wikipedia:Signal_transduction
signaling cascade
signalling cascade
biological_process
signaling pathway
signalling pathway
Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.
signal transduction
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GOC:go_curators
GOC:mtg_signaling_feb11
signalling pathway
GOC:mah
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
cell-cell signalling
biological_process
cell-cell signaling
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
GOC:dos
GOC:mah
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
biological_process
Note that this term was 'developmental process'.
multicellular organism development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GOC:dph
GOC:ems
GOC:isa_complete
GOC:tb
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
mitotic cell cycle modulation
mitotic cell cycle regulation
modulation of mitotic cell cycle progression
regulation of mitotic cell cycle progression
regulation of progression through mitotic cell cycle
biological_process
mitotic cell cycle regulator
regulation of mitotic cell cycle
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
GOC:dph
GOC:go_curators
GOC:tb
regulation of progression through mitotic cell cycle
GOC:dph
GOC:tb
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
biological_process
pan-neural process
nervous system development
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
GOC:dgh
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
GO:0016280
Wikipedia:Aging
ageing
biological_process
aging
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
GOC:PO_curators
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
molecular_function
microtubule severing activity
microtubule/chromatin interaction
microtubule binding
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
GOC:krc
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
tRNA maturation
biological_process
tRNA processing
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
GOC:jl
PMID:12533506
tRNA maturation
GOC:vw
Merging of two or more mitochondria within a cell to form a single compartment.
biological_process
mitochondrial fusion
Merging of two or more mitochondria within a cell to form a single compartment.
PMID:11038192
Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
molecular_function
cytoskeletal protein binding
Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
GOC:mah
Any process in which a protein is transported to, or maintained in, a specific location.
GO:0008105
protein localisation
biological_process
asymmetric protein localisation
asymmetric protein localization
establishment and maintenance of asymmetric protein localization
establishment and maintenance of protein localization
protein localization
Any process in which a protein is transported to, or maintained in, a specific location.
GOC:ai
protein localisation
GOC:mah
asymmetric protein localisation
GOC:mah
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
TF binding
molecular_function
transcription factor binding
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
ISBN:0198506732
Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome.
translation factor activity, nucleic acid binding
molecular_function
translation factor activity, RNA binding
Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome.
GOC:ai
GOC:vw
translation factor activity, nucleic acid binding
GOC:mah
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
janelomax
2012-10-17T15:46:40Z
GO:0044236
GO:0044710
Wikipedia:Metabolism
metabolism
metabolic process resulting in cell growth
metabolism resulting in cell growth
multicellular organism metabolic process
biological_process
single-organism metabolic process
Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GOC:go_curators
ISBN:0198547684
Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0004480
methylase
EC:2.1.1
Reactome:R-HSA-379387
Reactome:R-HSA-379464
Reactome:R-HSA-6800149
Reactome:R-HSA-71286
molecular_function
methyltransferase activity
Catalysis of the transfer of a methyl group to an acceptor molecule.
ISBN:0198506732
Reactome:R-HSA-379387
methylation of Dopamine to form 3-Methoxytyramine
Reactome:R-HSA-379464
Methylation of 3,4-dihydroxyphenylacetic acid to homovanillic acid
Reactome:R-HSA-6800149
N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII
Reactome:R-HSA-71286
guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
biological_process
accidental cell death
necrosis
This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.
cell death
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
GOC:mah
GOC:mtg_apoptosis
PMID:25236395
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
EC:3.4
Reactome:R-HSA-205112
Reactome:R-HSA-3000243
Reactome:R-HSA-3139027
Reactome:R-HSA-376149
Reactome:R-HSA-448678
Reactome:R-HSA-5655483
Reactome:R-HSA-5684864
Reactome:R-HSA-5685902
Reactome:R-HSA-5693319
hydrolase, acting on peptide bonds
peptide hydrolase activity
protease activity
proteinase activity
molecular_function
peptidase activity
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GOC:jl
ISBN:0815332181
Reactome:R-HSA-205112
gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6
Reactome:R-HSA-3000243
Unknown protease degrades GIF:Cbl to release Cbl
Reactome:R-HSA-3139027
Maturation of HIV Virion
Reactome:R-HSA-376149
Proteolytic processing of SLIT
Reactome:R-HSA-448678
CTSG cleaves CASP1(1-404)
Reactome:R-HSA-5655483
USP1 autocleavage
Reactome:R-HSA-5684864
NAPSA, CTSH, PGA3-5 cleave pro-SFTPB
Reactome:R-HSA-5685902
NAPSA, CTSH, PGA3-5 cleave pro-SFTPC
Reactome:R-HSA-5693319
CTRC hydrolyses PRSS1
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
biological_process
cell proliferation
This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms.
cell population proliferation
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
GOC:mah
GOC:mb
Any process that activates or increases the rate or extent of cell proliferation.
up regulation of cell proliferation
up-regulation of cell proliferation
upregulation of cell proliferation
activation of cell proliferation
stimulation of cell proliferation
biological_process
positive regulation of cell proliferation
positive regulation of cell population proliferation
Any process that activates or increases the rate or extent of cell proliferation.
GOC:go_curators
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
down regulation of cell proliferation
down-regulation of cell proliferation
downregulation of cell proliferation
inhibition of cell proliferation
biological_process
negative regulation of cell proliferation
negative regulation of cell population proliferation
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
GOC:go_curators
Interacting selectively and non-covalently with a lipid.
molecular_function
lipid binding
Interacting selectively and non-covalently with a lipid.
GOC:ai
Enables the transfer of a protein from one side of a membrane to the other.
GO:0015266
GO:0015463
Reactome:R-HSA-1268022
Reactome:R-HSA-1299475
Reactome:R-HSA-5205661
Reactome:R-HSA-5210943
Reactome:R-HSA-5210947
Reactome:R-HSA-5228406
Reactome:R-HSA-5244404
Reactome:R-HSA-5244428
Reactome:R-HSA-5244506
Reactome:R-HSA-5246514
Reactome:R-HSA-5250616
Reactome:R-HSA-5250884
Reactome:R-HSA-5250972
Reactome:R-HSA-5336420
molecular_function
protein channel activity
protein transmembrane transporter activity
GO_REF:0000090
Enables the transfer of a protein from one side of a membrane to the other.
GOC:jl
Reactome:R-HSA-1268022
TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space
Reactome:R-HSA-1299475
TIMM23 PAM translocates proteins from the mitochndrial intermebrane space to the mitochondrial matrix
Reactome:R-HSA-5205661
Pink1 is recruited from the cytoplasm to the mitochondria
Reactome:R-HSA-5210943
PA63:ANTRX2 oligomer transports EF and LF (target cell endosome to cytosol)
Reactome:R-HSA-5210947
PA63:ANTRX1 oligomer transports EF and LF (target cell endosome to cytosol)
Reactome:R-HSA-5228406
TeNT HC transports TeNT LC from target cell endosome membrane into cytosol
Reactome:R-HSA-5244404
BoNT/B HC transports BoNT/B LC from target cell synaptic vesicle membrane into cytosol
Reactome:R-HSA-5244428
BoNT/A HC transports BoNT/A LC from target cell synaptic vesicle membrane into cytosol
Reactome:R-HSA-5244506
BoNT/E HC transports BoNT/E LC from target cell synaptic vesicle membrane into cytosol
Reactome:R-HSA-5246514
BoNT/C HC transports BoNT/C LC from target cell synaptic vesicle membrane to cytosol
Reactome:R-HSA-5250616
BoNT/D HC transports BoNT/D LC from target cell synaptic vesicle membrane into cytosol
Reactome:R-HSA-5250884
BoNT/F HC transports BoNT/F LC from target cell synaptic vesicle membrane into cytosol
Reactome:R-HSA-5250972
BoNT/G HC transports BoNT/G LC from target cell synaptic vesicle membrane into cytosol
Reactome:R-HSA-5336420
DT fragment B transports DT fragment A from target cell endosome membrane
The directed movement of substances from endosomes to lysosomes.
biological_process
endosome to lysosome transport
The directed movement of substances from endosomes to lysosomes.
GOC:ai
ISBN:0716731363
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
lipid anabolism
lipid biosynthesis
lipid formation
lipid synthesis
lipogenesis
biological_process
lipid biosynthetic process
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
GOC:go_curators
lipogenesis
GOC:sl
The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.
GO:0006861
GO:0008644
sugar transport
biological_process
carbohydrate transport
The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.
GOC:ai
The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
Wikipedia:Amino_acid_synthesis
amino acid biosynthetic process
cellular amino acid anabolism
cellular amino acid biosynthesis
cellular amino acid formation
cellular amino acid synthesis
biological_process
cellular amino acid biosynthetic process
The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
ISBN:0198506732
The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
janelomax
2012-10-17T15:52:35Z
GO:0044243
GO:0044712
Wikipedia:Catabolism
breakdown
catabolism
degradation
multicellular organismal catabolic process
biological_process
single-organism catabolic process
catabolic process
The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
ISBN:0198547684
The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0043285
GO:0044266
biopolymer catabolic process
macromolecule breakdown
macromolecule catabolism
macromolecule degradation
multicellular organismal macromolecule catabolic process
biological_process
macromolecule catabolic process
The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:mah
biopolymer catabolic process
GOC:mtg_chebi_dec09
The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
janelomax
2012-10-17T15:52:18Z
GO:0044274
GO:0044711
formation
Wikipedia:Anabolism
anabolism
biosynthesis
synthesis
multicellular organismal biosynthetic process
biological_process
single-organism biosynthetic process
biosynthetic process
The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GOC:curators
ISBN:0198547684
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0043284
biopolymer biosynthetic process
macromolecule anabolism
macromolecule biosynthesis
macromolecule formation
macromolecule synthesis
biological_process
macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:mah
biopolymer biosynthetic process
GOC:mtg_chebi_dec09
The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.
amino acid catabolic process
cellular amino acid breakdown
cellular amino acid catabolism
cellular amino acid degradation
biological_process
cellular amino acid catabolic process
The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.
GOC:ai
The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.
Wikipedia:Nucleoid
cellular_component
nucleoid
The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.
GOC:bm
GOC:ma
ISBN:3540076689
The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.
rRNA biosynthesis
rRNA biosynthetic process
rRNA synthesis
biological_process
rRNA transcription
The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.
GOC:jl
ISBN:0198506732
The synthesis of transfer RNA (tRNA) from a DNA template.
tRNA biosynthesis
tRNA biosynthetic process
tRNA synthesis
biological_process
tRNA transcription
The synthesis of transfer RNA (tRNA) from a DNA template.
GOC:jl
The controlled release of proteins from a cell.
GO:0045166
GO:0045731
glycoprotein secretion
protein secretion during cell fate commitment
protein secretion resulting in cell fate commitment
biological_process
protein secretion
The controlled release of proteins from a cell.
GOC:ai
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
amine metabolism
biological_process
amine metabolic process
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
GOC:jl
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
amine anabolism
amine biosynthesis
amine formation
amine synthesis
biological_process
amine biosynthetic process
The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
GOC:jl
ISBN:0198506732
The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
amine breakdown
amine catabolism
amine degradation
biological_process
amine catabolic process
The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
GOC:jl
ISBN:0198506732
A circular DNA molecule containing plastid encoded genes.
cellular_component
plastid chromosome
A circular DNA molecule containing plastid encoded genes.
ISBN:0943088399
The proteinaceous ground substance of plastids.
cellular_component
plastid stroma
The proteinaceous ground substance of plastids.
ISBN:0943088399
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
Wikipedia:Plastid
cellular_component
plastid
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
GOC:jl
ISBN:0198547684
A ribosome contained within a plastid.
cellular_component
plastid ribosome
A ribosome contained within a plastid.
GOC:tair_curators
A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
Wikipedia:Thylakoid
cellular_component
photosynthetic membrane
A thylakoid is not considered an organelle, but some thylakoids are part of organelles.
thylakoid
A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
GOC:ds
GOC:mtg_sensu
ISBN:0198506732
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
embryogenesis and morphogenesis
Wikipedia:Morphogenesis
anatomical structure organization
morphogenesis
biological_process
anatomical structure morphogenesis
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
GOC:go_curators
ISBN:0521436125
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid.
plastid organisation
biological_process
plastid organization and biogenesis
plastid organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid.
GOC:mah
plastid organization and biogenesis
GOC:mah
The partitioning of plastids between daughter cells at cell division.
biological_process
plastid inheritance
The partitioning of plastids between daughter cells at cell division.
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
response to carbohydrate stimulus
biological_process
response to carbohydrate
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
GOC:jl
response to carbohydrate stimulus
GOC:dos
The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.
GO:0009795
embryogenesis and morphogenesis
Wikipedia:Embryogenesis
embryogenesis
embryonal development
biological_process
embryo development
The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.
GOC:go_curators
GOC:isa_complete
GOC:mtg_sensu
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
regulation of anabolism
regulation of biosynthesis
regulation of formation
regulation of synthesis
biological_process
regulation of biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GOC:go_curators
Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
down regulation of biosynthetic process
down-regulation of biosynthetic process
downregulation of biosynthetic process
negative regulation of anabolism
negative regulation of biosynthesis
negative regulation of formation
negative regulation of synthesis
inhibition of biosynthetic process
biological_process
negative regulation of biosynthetic process
Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
positive regulation of anabolism
positive regulation of biosynthesis
positive regulation of formation
positive regulation of synthesis
up regulation of biosynthetic process
up-regulation of biosynthetic process
upregulation of biosynthetic process
activation of biosynthetic process
stimulation of biosynthetic process
biological_process
positive regulation of biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0044252
down regulation of metabolic process
down-regulation of metabolic process
downregulation of metabolic process
negative regulation of metabolism
negative regulation of organismal metabolism
inhibition of metabolic process
inhibition of organismal metabolic process
negative regulation of multicellular organismal metabolic process
biological_process
negative regulation of metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0044253
positive regulation of metabolism
up regulation of metabolic process
up-regulation of metabolic process
upregulation of metabolic process
activation of metabolic process
positive regulation of multicellular organismal metabolic process
positive regulation of organismal metabolism
stimulation of metabolic process
stimulation of organismal metabolic process
up-regulation of organismal metabolic process
biological_process
positive regulation of metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GOC:go_curators
Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.
regulation of breakdown
regulation of catabolism
regulation of degradation
biological_process
regulation of catabolic process
Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
down regulation of catabolic process
down-regulation of catabolic process
downregulation of catabolic process
negative regulation of breakdown
negative regulation of catabolism
negative regulation of degradation
inhibition of catabolic process
biological_process
negative regulation of catabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
positive regulation of breakdown
positive regulation of catabolism
positive regulation of degradation
up regulation of catabolic process
up-regulation of catabolic process
upregulation of catabolic process
activation of catabolic process
stimulation of catabolic process
biological_process
positive regulation of catabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
GOC:go_curators
Any process that modulates the frequency, rate or extent of signal transduction.
GO:0035466
biological_process
regulation of signaling pathway
regulation of signalling pathway
regulation of signal transduction
Any process that modulates the frequency, rate or extent of signal transduction.
GOC:sm
regulation of signalling pathway
GOC:mah
Any process that activates or increases the frequency, rate or extent of signal transduction.
GO:0035468
up regulation of signal transduction
up-regulation of signal transduction
upregulation of signal transduction
activation of signal transduction
stimulation of signal transduction
biological_process
positive regulation of signaling pathway
positive regulation of signalling pathway
positive regulation of signal transduction
Any process that activates or increases the frequency, rate or extent of signal transduction.
GOC:sm
positive regulation of signalling pathway
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
GO:0035467
down regulation of signal transduction
down-regulation of signal transduction
downregulation of signal transduction
inhibition of signal transduction
biological_process
negative regulation of signaling pathway
negative regulation of signalling pathway
negative regulation of signal transduction
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
GOC:sm
negative regulation of signalling pathway
GOC:mah
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
janelomax
2012-12-11T16:56:55Z
GO:0008151
GO:0044763
GO:0050875
cell physiology
cellular physiological process
cell growth and/or maintenance
biological_process
single-organism cellular process
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GOC:go_curators
GOC:isa_complete
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
GO:1990367
process resulting in tolerance to organic substance
biological_process
response to organic substance
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
GOC:sm
PMID:23356676
Any process that modulates the frequency, rate or extent of photosynthesis.
biological_process
regulation of photosynthesis
Any process that modulates the frequency, rate or extent of photosynthesis.
GOC:sm
The process in which the anatomical structures of the soma are generated and organized.
biological_process
body morphogenesis
The process in which the anatomical structures of the soma are generated and organized.
GOC:ems
ISBN:0140512888
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
response to organic nitrogen
biological_process
response to organonitrogen compound
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
PMID:9869419
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.
endomembrane organization
endomembrane system organisation
biological_process
endomembrane system organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.
GOC:mah
GOC:sm
endomembrane system organisation
GOC:mah
Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
biological_process
negative regulation of peptidase activity
Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
GOC:dph
GOC:tb
The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
Wikipedia:Gene_expression
biological_process
gene expression
The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
Wikipedia:Regulation_of_gene_expression
regulation of protein expression
biological_process
regulation of gene product expression
This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation.
regulation of gene expression
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GOC:dph
GOC:tb
The movement of substances between cells.
jl
2013-12-19T13:24:56Z
GO:1902585
biological_process
single organism intercellular transport
single-organism intercellular transport
intercellular transport
The movement of substances between cells.
GOC:dhl
single organism intercellular transport
GOC:TermGenie
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
proteasome-mediated protein catabolic process
proteasome-mediated protein catabolism
biological_process
proteasomal protein catabolic process
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
GOC:tb
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
biological_process
regulation of autophagy
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
biological_process
negative regulation of autophagy
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
GOC:dph
GOC:tb
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
biological_process
positive regulation of autophagy
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
biological_process
regulation of transposition
Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
biological_process
negative regulation of transposition
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
biological_process
positive regulation of transposition
Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of membrane disassembly.
biological_process
regulation of membrane disassembly
Any process that modulates the frequency, rate or extent of membrane disassembly.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
regulation of macromolecule biosynthetic process
Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
positive regulation of macromolecule biosynthetic process
Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
negative regulation of macromolecule biosynthetic process
Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
biological_process
regulation of cell cycle process
Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
GOC:dph
GOC:tb
Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
biological_process
regulation of cellular ketone metabolic process
Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.
biological_process
regulation of ketone biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells.
biological_process
regulation of ketone catabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
positive regulation of macromolecule metabolic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
negative regulation of macromolecule metabolic process
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
biological_process
posttranscriptional regulation of gene expression
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
GOC:dph
GOC:tb
The activation of endogenous cellular processes that result in the death of a cell as part of its development.
developmental programmed cell death
programmed cell death involved in development
biological_process
This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure.
programmed cell death involved in cell development
The activation of endogenous cellular processes that result in the death of a cell as part of its development.
GOC:dph
GOC:mtg_apoptosis
GOC:tb
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
biological_process
positive regulation of gene expression
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
biological_process
This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation.
negative regulation of gene expression
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
biological_process
regulation of mitochondrial fusion
Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
biological_process
positive regulation of mitochondrial fusion
Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
biological_process
negative regulation of mitochondrial fusion
Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
positive regulation of organelle organisation
biological_process
positive regulation of organelle organization and biogenesis
positive regulation of organelle organization
Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
GOC:dph
GOC:tb
positive regulation of organelle organisation
GOC:mah
positive regulation of organelle organization and biogenesis
GOC:mah
Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
negative regulation of organelle organisation
biological_process
negative regulation of organelle organization and biogenesis
negative regulation of organelle organization
Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
GOC:dph
GOC:tb
negative regulation of organelle organisation
GOC:mah
negative regulation of organelle organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
biological_process
regulation of cell communication
Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
biological_process
positive regulation of cell communication
Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
biological_process
negative regulation of cell communication
Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
regulation of extracellular matrix breakdown
regulation of extracellular matrix degradation
biological_process
regulation of extracellular matrix disassembly
Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
GOC:BHF
GOC:dph
GOC:tb
regulation of extracellular matrix breakdown
GOC:dph
GOC:tb
regulation of extracellular matrix degradation
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
down regulation of extracellular matrix disassembly
down-regulation of extracellular matrix disassembly
downregulation of extracellular matrix disassembly
negative regulation of extracellular matrix breakdown
negative regulation of extracellular matrix degradation
inhibition of extracellular matrix disassembly
biological_process
negative regulation of extracellular matrix disassembly
Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
GOC:BHF
GOC:dph
GOC:tb
down regulation of extracellular matrix disassembly
GOC:dph
GOC:tb
down-regulation of extracellular matrix disassembly
GOC:dph
GOC:tb
downregulation of extracellular matrix disassembly
GOC:dph
GOC:tb
negative regulation of extracellular matrix breakdown
GOC:dph
GOC:tb
negative regulation of extracellular matrix degradation
GOC:dph
GOC:tb
inhibition of extracellular matrix disassembly
GOC:dph
GOC:tb
Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
biological_process
positive regulation of cell development
Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GOC:BHF
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
biological_process
negative regulation of cell development
Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GOC:BHF
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
biological_process
regulation of cell morphogenesis involved in differentiation
Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
biological_process
positive regulation of cell morphogenesis involved in differentiation
Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
biological_process
negative regulation of cell morphogenesis involved in differentiation
Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
regulation of mitochondrion organisation
biological_process
regulation of mitochondrion organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
GOC:dph
GOC:tb
regulation of mitochondrion organisation
GOC:mah
Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
positive regulation of mitochondrion organisation
biological_process
positive regulation of mitochondrion organization
Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
GOC:dph
GOC:tb
positive regulation of mitochondrion organisation
GOC:mah
Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
negative regulation of mitochondrion organisation
biological_process
negative regulation of mitochondrion organization
Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
GOC:dph
GOC:tb
negative regulation of mitochondrion organisation
GOC:mah
Any process in which a lipid is transported to, or maintained in, a specific location.
lipid localisation
biological_process
lipid localization
Any process in which a lipid is transported to, or maintained in, a specific location.
GOC:BHF
GOC:dph
GOC:tb
lipid localisation
GOC:mah
Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
biological_process
regulation of isomerase activity
Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GOC:dph
GOC:tb
Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
biological_process
positive regulation of isomerase activity
Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GOC:dph
GOC:tb
Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
biological_process
regulation of phosphatase activity
Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GOC:BHF
GOC:dph
GOC:tb
Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
biological_process
positive regulation of phosphatase activity
Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GOC:BHF
GOC:dph
GOC:tb
Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
biological_process
negative regulation of phosphatase activity
Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GOC:BHF
GOC:dph
GOC:tb
The cellular component assembly that is part of the initial shaping of the component during its developmental progression.
biological_process
cellular component assembly involved in morphogenesis
The cellular component assembly that is part of the initial shaping of the component during its developmental progression.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.
biological_process
regulation of cytoplasmic microtubule depolymerization
Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.
GOC:dph
GOC:tb
The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.
biological_process
cytoplasmic microtubule depolymerization
The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.
GOC:dph
GOC:tb
Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
biological_process
regulation of cell death
Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
GOC:dph
GOC:tb
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
biological_process
positive regulation of cell death
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
tanyaberardini
2009-04-27T09:53:22Z
biological_process
negative regulation of cell cycle process
Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
tanyaberardini
2009-04-27T11:45:39Z
biological_process
positive regulation of endopeptidase activity
Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
GOC:dph
GOC:tb
Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
tanyaberardini
2009-04-27T11:47:01Z
biological_process
negative regulation of endopeptidase activity
Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
GOC:dph
GOC:tb
Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
tanyaberardini
2009-04-27T11:54:32Z
biological_process
positive regulation of peptidase activity
Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
tanyaberardini
2009-05-20T11:51:21Z
biological_process
regulation of microtubule nucleation
Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
GOC:dph
GOC:tb
The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.
tanyaberardini
2009-05-27T10:56:08Z
microtubule-based transport
establishment of localization by movement along microtubule
movement along microtubule
biological_process
transport along microtubule
The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.
GOC:dph
GOC:mah
GOC:tb
establishment of localization by movement along microtubule
GOC:dph
Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
tanyaberardini
2009-06-01T11:55:35Z
biological_process
regulation of cell wall macromolecule metabolic process
Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GOC:dph
GOC:tb
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0016244
regulated cell death
Wikipedia:Programmed_cell_death
caspase-independent cell death
non-apoptotic programmed cell death
nonapoptotic programmed cell death
biological_process
PCD
RCD
caspase-independent apoptosis
Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children.
programmed cell death
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GOC:lr
GOC:mtg_apoptosis
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
Wikipedia:Endomembrane_system
cellular_component
endomembrane system
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
GOC:lh
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
NIF_Subcellular:sao1153182838
cellular_component
vesicle membrane
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
GOC:mah
GOC:vesicle
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
response to amine stimulus
biological_process
response to amine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
GOC:ef
response to amine stimulus
GOC:dos
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015831
enzyme transport
biological_process
protein transport
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Enables the transfer of an ion from one side of a membrane to the other.
ion transporter activity
molecular_function
ion transmembrane transporter activity
GO_REF:0000090
Enables the transfer of an ion from one side of a membrane to the other.
GOC:dgf
GOC:mtg_transport
ISBN:0815340729
Enables the transfer of carbohydrate from one side of a membrane to the other.
GO:1901476
sugar transporter
molecular_function
carbohydrate transporter activity
carbohydrate transmembrane transporter activity
GO_REF:0000090
Enables the transfer of carbohydrate from one side of a membrane to the other.
GOC:jl
GOC:mtg_transport
ISBN:0815340729
Enables the transfer of a solute from one side of a membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source, directly using ATP. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources.
TC:3
molecular_function
primary active transporter
primary active transmembrane transporter activity
Enables the transfer of a solute from one side of a membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source, directly using ATP. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources.
GOC:mtg_transport
ISBN:0815340729
TC:3.-.-.-.-
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
cellular_component
microtubule cytoskeleton
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
GOC:jl
ISBN:0395825172
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
molecular_function
tubulin binding
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
GOC:clt
The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
amine/polyamine transport
amine transport
The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
ISBN:0198506732
The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
organic acid transport
The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
ISBN:0198506732
The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
nucleobase, nucleoside, nucleotide and nucleic acid transport
nucleobase-containing compound transport
The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
nucleobase, nucleoside, nucleotide and nucleic acid transport
GOC:dph
GOC:tb
Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other.
molecular_function
nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity
nucleobase-containing compound transmembrane transporter activity
Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other.
GOC:ai
nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity
GOC:dph
GOC:tb
The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.
Wikipedia:Photosynthesis
biological_process
photosynthesis
The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.
ISBN:0198547684
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
Wikipedia:Biological_membrane
cellular_component
membrane
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GOC:dos
GOC:mah
ISBN:0815316194
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Wikipedia:Transmembrane_protein
integral to membrane
cellular_component
transmembrane
integral component of membrane
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GOC:dos
GOC:go_curators
transmembrane
GOC:mah
The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
GO:0006724
GO:0044240
Wikipedia:Lipid_catabolism
lipid breakdown
lipid catabolism
lipid degradation
lipolysis
multicellular organism lipid catabolic process
multicellular organismal lipid catabolic process
biological_process
lipid catabolic process
The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
GOC:go_curators
A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0044235
GO:0071842
cell organisation
cellular component organisation at cellular level
cellular component organisation in other organism
cellular component organization at cellular level
cellular component organization in other organism
biological_process
cell organization and biogenesis
cellular component organization
A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GOC:ai
GOC:jl
GOC:mah
cellular component organisation at cellular level
GOC:mah
cellular component organisation in other organism
GOC:mah
cell organization and biogenesis
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
vesicle organisation
biological_process
vesicle organization and biogenesis
vesicle organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
GOC:mah
vesicle organization and biogenesis
GOC:mah
The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
GO:0006093
anabolic carbohydrate metabolic process
anabolic carbohydrate metabolism
carbohydrate anabolism
carbohydrate biosynthesis
carbohydrate formation
carbohydrate synthesis
biological_process
carbohydrate biosynthetic process
The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
ISBN:0198506732
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
janelomax
2012-10-23T16:34:39Z
GO:0006095
GO:0044276
GO:0044724
carbohydrate breakdown
carbohydrate catabolism
carbohydrate degradation
catabolic carbohydrate metabolic process
catabolic carbohydrate metabolism
multicellular organismal carbohydrate catabolic process
biological_process
single-organism carbohydrate catabolic process
carbohydrate catabolic process
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.
organic acid anabolism
organic acid biosynthesis
organic acid formation
organic acid synthesis
biological_process
organic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.
ISBN:0198506732
The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.
organic acid breakdown
organic acid catabolism
organic acid degradation
biological_process
organic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.
ISBN:0198506732
The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
RNA metabolism
biological_process
RNA metabolic process
The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
ISBN:0198506732
The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
mRNA metabolism
biological_process
mRNA metabolic process
The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
ISBN:0198506732
The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes.
rRNA metabolism
biological_process
rRNA metabolic process
The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes.
ISBN:0198506732
The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes.
rRNA breakdown
rRNA catabolism
rRNA degradation
biological_process
rRNA catabolic process
The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes.
GOC:ai
The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis.
tRNA breakdown
tRNA catabolism
tRNA degradation
biological_process
tRNA catabolic process
The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis.
GOC:ai
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GO:0006899
vesicle transport
vesicular transport
nonselective vesicle transport
biological_process
protein sorting along secretory pathway
vesicle trafficking
vesicle-mediated transport
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GOC:ai
GOC:mah
ISBN:08789310662000
vesicular transport
GOC:mah
The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane.
GO:0032439
endosome localisation
biological_process
endosome localization
endosome transport
endosomal transport
The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane.
ISBN:0198506732
endosome localisation
GOC:mah
endosome transport
GOC:bf
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
Reactome:R-HSA-6788855
Reactome:R-HSA-6788867
phosphokinase activity
molecular_function
Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term.
kinase activity
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
ISBN:0198506732
Reactome:R-HSA-6788855
FN3KRP phosphorylates PsiAm, RibAm
Reactome:R-HSA-6788867
FN3K phosphorylates ketosamines
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
Wikipedia:Phosphorylation
biological_process
phosphorylation
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
ISBN:0198506732
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
Wikipedia:Dephosphorylation
biological_process
dephosphorylation
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
ISBN:0198506732
Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
Reactome:R-HSA-6810472
molecular_function
pyrophosphatase activity
Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
EC:3.6.1.-
GOC:curators
Reactome:R-HSA-6810472
NUDT13 hydrolyses AP6A to AP4 and ADP
The directed movement of substances or organelles within the cytosol.
biological_process
cytosolic transport
The directed movement of substances or organelles within the cytosol.
GOC:ai
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
EC:1
Reactome:R-HSA-1614362
Reactome:R-HSA-209921
Reactome:R-HSA-209960
Reactome:R-HSA-3095889
Reactome:R-HSA-390425
Reactome:R-HSA-390438
Reactome:R-HSA-5662660
Reactome:R-HSA-8878581
Reactome:R-HSA-8936442
Reactome:R-HSA-9020249
Reactome:R-HSA-9020260
Reactome:R-HSA-9024624
Reactome:R-HSA-9024630
Reactome:R-HSA-9025007
Reactome:R-HSA-9026001
Reactome:R-HSA-9026917
Reactome:R-HSA-9027033
redox activity
oxidoreductase activity, acting on other substrates
molecular_function
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GOC:go_curators
Reactome:R-HSA-1614362
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases
Reactome:R-HSA-209921
Monoiodinated tyrosine can be deiodinated
Reactome:R-HSA-209960
Diiodinated tyrosine can be deiodinated
Reactome:R-HSA-3095889
MMACHC reduces Cbl
Reactome:R-HSA-390425
FAR1 reduces PalmCoA to HXOL
Reactome:R-HSA-390438
FAR2 reduces PalmCoA to HXOL
Reactome:R-HSA-5662660
Dopachrome is transformed to DHICA by DCT
Reactome:R-HSA-8878581
TYRP1 oxidises DHICA to IQCA
Reactome:R-HSA-8936442
MARC1,MARC2 reduce N-hydroxylated compounds
Reactome:R-HSA-9020249
Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6
Reactome:R-HSA-9020260
Hydroperoxy reducatse reduces 7(S)-Hp-17(S)-HDHA to RvD5
Reactome:R-HSA-9024624
Hydroperoxy reductase reduces 4(S)-Hp-17(R)-HDHA to AT-RvD6
Reactome:R-HSA-9024630
Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5
Reactome:R-HSA-9025007
Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1
Reactome:R-HSA-9026001
Hydroperoxy reductase reduces 7,17-diHp-DPAn-3 to RvD5n-3DPA
Reactome:R-HSA-9026917
Lipoxygenase dehydrogenates 7(S),17(S)-diHp-DHA to 7S(8)-epoxy-17(S)-HDHA
Reactome:R-HSA-9027033
Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
peroxisome division
peroxisome proliferation
biological_process
peroxisome fission
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
GOC:mah
PMID:11687502
PMID:14754507
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
molecular_function
amino acid binding
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
GOC:ai
Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
EC:2
Reactome:R-HSA-1483089
Reactome:R-HSA-1483186
Reactome:R-HSA-5668414
Reactome:R-HSA-6787403
Reactome:R-HSA-8868783
molecular_function
transferase activity
Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
ISBN:0198506732
Reactome:R-HSA-1483089
PE is converted to PS by PTDSS2
Reactome:R-HSA-1483186
PC is converted to PS by PTDSS1
Reactome:R-HSA-5668414
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK
Reactome:R-HSA-6787403
GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA
Reactome:R-HSA-8868783
TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248
Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).
EC:2.1
molecular_function
transferase activity, transferring one-carbon groups
Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).
GOC:jl
ISBN:0198506732
Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
GO:0008415
EC:2.3
Reactome:R-HSA-159431
Reactome:R-HSA-192312
Reactome:R-HSA-193491
Reactome:R-HSA-6792572
Reactome:R-HSA-8858298
acyltransferase activity
molecular_function
transferase activity, transferring acyl groups
Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
GOC:jl
ISBN:0198506732
Reactome:R-HSA-159431
Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine
Reactome:R-HSA-192312
Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate
Reactome:R-HSA-193491
Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate
Reactome:R-HSA-6792572
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs
Reactome:R-HSA-8858298
HRASLS transfer acyl group from PC to PE to form NAPE
Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
GO:0016932
EC:2.4
Reactome:R-HSA-5173005
Reactome:R-HSA-6785565
glycosyltransferase activity
transglycosidase activity
transglycosylase activity
transferase activity, transferring other glycosyl groups
molecular_function
transferase activity, transferring glycosyl groups
Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
GOC:jl
ISBN:0198506732
Reactome:R-HSA-5173005
B3GALTL transfers glucose to O-fucosyl-proteins
Reactome:R-HSA-6785565
Defective B3GALTL does not transfer glucose to O-fucosyl-proteins
Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).
GO:0016766
EC:2.5
EC:2.5.1
Reactome:R-HSA-4419978
Reactome:R-HSA-4755545
Reactome:R-HSA-6782893
transferase activity, transferring alkyl or aryl groups, other than methyl groups
molecular_function
transferase activity, transferring alkyl or aryl (other than methyl) groups
Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).
GOC:jl
ISBN:0198506732
Reactome:R-HSA-4419978
DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP
Reactome:R-HSA-4755545
Defective DHDDS does not elongate E,E-FPP
Reactome:R-HSA-6782893
TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe)
Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
EC:2.7
molecular_function
Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides.
transferase activity, transferring phosphorus-containing groups
Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GOC:jl
ISBN:0198506732
Catalysis of the transfer of a nucleotidyl group to a reactant.
EC:2.7.7
Reactome:R-HSA-6782434
molecular_function
nucleotidyltransferase activity
Catalysis of the transfer of a nucleotidyl group to a reactant.
ISBN:0198506732
Reactome:R-HSA-6782434
THG1L transfers GMP to 5' end of tRNA(His)
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
EC:3
Reactome:R-HSA-1236938
Reactome:R-HSA-2029475
Reactome:R-HSA-5694583
Reactome:R-HSA-5695964
Reactome:R-HSA-6786190
Reactome:R-HSA-6788295
Reactome:R-HSA-8938314
Reactome:R-HSA-8952137
molecular_function
hydrolase activity
Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
ISBN:0198506732
Reactome:R-HSA-1236938
Partial proteolysis of antigen in phagolysosomes
Reactome:R-HSA-2029475
Production of AA by iPLA2 upon FCGR activation
Reactome:R-HSA-5694583
ABHD4 hydrolyses NAPE
Reactome:R-HSA-5695964
ABHD14B hydrolyses PNPB
Reactome:R-HSA-6786190
CMBL hydrolyses OM to OLMS
Reactome:R-HSA-6788295
HDHD1:Mg2+ dephosphorylates PURIDP
Reactome:R-HSA-8938314
ENPPs hydrolyse CoA-SH to PPANT, PAP
Reactome:R-HSA-8952137
Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate
Catalysis of the hydrolysis of any ester bond.
EC:3.1
Reactome:R-HSA-162729
Reactome:R-HSA-9023617
Reactome:R-HSA-9023619
esterase activity
molecular_function
hydrolase activity, acting on ester bonds
Catalysis of the hydrolysis of any ester bond.
GOC:jl
Reactome:R-HSA-162729
uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid
Reactome:R-HSA-9023617
Butyrylcholinesterase hydrolyzes acyl Ghrelin
Reactome:R-HSA-9023619
Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
GO:0003869
GO:0016302
EC:3.1.3
MetaCyc:4-NITROPHENYLPHOSPHATASE-RXN
RHEA:21664
Reactome:R-HSA-4419986
phosphoric monoester hydrolase activity
4-nitrophenylphosphatase activity
4-nitrophenylphosphate phosphohydrolase activity
K-pNPPase activity
NPPase activity
PNPPase activity
ecto-p-nitrophenyl phosphatase activity
nitrophenyl phosphatase activity
p-nitrophenylphosphatase activity
p-nitrophenylphosphate phosphohydrolase activity
para-nitrophenyl phosphatase activity
molecular_function
phosphatase
phosphatase activity
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
EC:3.1.3
GOC:curators
GOC:pg
Reactome:R-HSA-4419986
Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL
4-nitrophenylphosphate phosphohydrolase activity
EC:3.1.3.41
K-pNPPase activity
EC:3.1.3.41
NPPase activity
EC:3.1.3.41
PNPPase activity
EC:3.1.3.41
ecto-p-nitrophenyl phosphatase activity
EC:3.1.3.41
nitrophenyl phosphatase activity
EC:3.1.3.41
p-nitrophenylphosphatase activity
EC:3.1.3.41
p-nitrophenylphosphate phosphohydrolase activity
EC:3.1.3.41
para-nitrophenyl phosphatase activity
EC:3.1.3.41
Catalysis of the hydrolysis of any glycosyl bond.
EC:3.2
Reactome:R-HSA-1793176
Reactome:R-HSA-2065233
glycosidase activity
N-glycosylase
glycosylase
molecular_function
hydrolase activity, acting on glycosyl bonds
Catalysis of the hydrolysis of any glycosyl bond.
GOC:jl
Reactome:R-HSA-1793176
DS is cleaved from its proteoglycan
Reactome:R-HSA-2065233
CS is cleaved from its proteoglycan
Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
EC:3.5
Reactome:R-HSA-6803753
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds
molecular_function
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
GOC:jl
Reactome:R-HSA-6803753
NAAA hydrolyses NAEs to FAs and ethanolamine
Catalysis of the hydrolysis of any acid anhydride.
EC:3.6
hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement
molecular_function
hydrolase activity, acting on acid anhydrides
Catalysis of the hydrolysis of any acid anhydride.
GOC:jl
Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
EC:3.6.1
molecular_function
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GOC:jl
Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
EC:4
Reactome:R-HSA-5696408
Reactome:R-HSA-6782895
other lyase activity
molecular_function
lyase activity
Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
ISBN:0198547684
Reactome:R-HSA-5696408
PHYKPL tetramer hydrolyses 5PHL
Reactome:R-HSA-6782895
TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe)
Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
EC:5
Reactome:R-HSA-6787623
other isomerase activity
molecular_function
isomerase activity
Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
ISBN:0198506732
Reactome:R-HSA-6787623
TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal
Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
EC:6
synthetase activity
molecular_function
ligase activity
Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
EC:6
GOC:mah
synthetase activity
GOC:jh2
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
https://github.com/geneontology/go-ontology/issues/19078
GO:0004002
GO:0042623
EC:3.6.1.3
MetaCyc:ADENOSINETRIPHOSPHATASE-RXN
RHEA:13065
Reactome:R-HSA-159101
Reactome:R-HSA-3371422
Reactome:R-HSA-416985
Reactome:R-HSA-5618093
Reactome:R-HSA-5654989
Reactome:R-HSA-5694425
Reactome:R-HSA-6809015
Reactome:R-HSA-6811422
Reactome:R-HSA-6814670
Reactome:R-HSA-6814678
Reactome:R-HSA-6814683
Reactome:R-HSA-72139
Reactome:R-HSA-8847638
Reactome:R-HSA-8868658
Reactome:R-HSA-8939203
Reactome:R-HSA-9038161
Reactome:R-HSA-917693
Reactome:R-HSA-9609860
ATP hydrolase activity
ATP monophosphatase activity
ATP phosphohydrolase activity
adenosine 5'-triphosphatase activity
adenosine triphosphatase activity
adenosinetriphosphatase activity
(Ca2+ + Mg2+)-ATPase
ATP phosphohydrolase (polypeptide-unfolding)
HCO3--ATPase
complex V (mitochondrial electron transport)
molecular_function
ATPase activity, coupled
SV40 T-antigen
chaperonin
chaperonin ATPase activity
non-chaperonin molecular chaperone ATPase activity
nucleoplasmin ATPase activity
peroxisome-assembly ATPase activity
vesicle-fusing ATPase activity
ATPase activity
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
EC:3.6.1.3
GOC:jl
Reactome:R-HSA-159101
NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)
Reactome:R-HSA-3371422
ATP hydrolysis by HSP70
Reactome:R-HSA-416985
Trafficking of GluR2-containing AMPA receptors to synapse
Reactome:R-HSA-5618093
ATP hydrolysis by HSP90
Reactome:R-HSA-5654989
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA
Reactome:R-HSA-5694425
NSF ATPase activity dissociates cis-SNARE
Reactome:R-HSA-6809015
NSF ATPase activity dissociates cis-SNARE at cis-Golgi
Reactome:R-HSA-6811422
NSF ATPase activity dissociates cis-SNARE at the ER
Reactome:R-HSA-6814670
ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation
Reactome:R-HSA-6814678
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN
Reactome:R-HSA-6814683
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN
Reactome:R-HSA-72139
Formation of the active Spliceosomal C (B*) complex
Reactome:R-HSA-8847638
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane
Reactome:R-HSA-8868658
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating
Reactome:R-HSA-8939203
HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex
Reactome:R-HSA-9038161
Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG
Reactome:R-HSA-917693
ESCRT Disassembly
Reactome:R-HSA-9609860
Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP
ATP hydrolase activity
EC:3.6.1.3
ATP monophosphatase activity
EC:3.6.1.3
adenosine 5'-triphosphatase activity
EC:3.6.1.3
adenosine triphosphatase activity
EC:3.6.1.3
(Ca2+ + Mg2+)-ATPase
EC:3.6.1.3
ATP phosphohydrolase (polypeptide-unfolding)
EC:3.6.4.9
HCO3--ATPase
EC:3.6.1.3
complex V (mitochondrial electron transport)
EC:3.6.1.3
SV40 T-antigen
EC:3.6.1.3
chaperonin
EC:3.6.4.9
vesicle-fusing ATPase activity
EC:3.6.4.6
The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall.
GO:0044039
cellular cell wall macromolecule breakdown
cellular cell wall macromolecule catabolic process
cellular cell wall macromolecule catabolism
cellular cell wall macromolecule degradation
biological_process
cell wall breakdown
cell wall catabolism
cell wall degradation
cell wall macromolecule catabolic process
The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall.
GOC:go_curators
cellular cell wall macromolecule breakdown
GOC:mah
cellular cell wall macromolecule catabolism
GOC:mah
cellular cell wall macromolecule degradation
GOC:mah
cell wall breakdown
GOC:mah
cell wall catabolism
GOC:mah
cell wall degradation
GOC:mah
Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
apyrase activity
EC:3.6.1.15
MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN
RHEA:23680
Reactome:R-HSA-8850846
Reactome:R-HSA-8851089
Reactome:R-HSA-8851110
Reactome:R-HSA-8851234
Reactome:R-HSA-8851494
Reactome:R-HSA-8851538
NTPase activity
nucleoside 5-triphosphatase activity
nucleoside triphosphatase activity
nucleoside triphosphate hydrolase activity
nucleoside triphosphate phosphohydrolase activity
nucleoside-5-triphosphate phosphohydrolase activity
unspecific diphosphate phosphohydrolase activity
molecular_function
nucleoside-triphosphatase activity
Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
EC:3.6.1.15
Reactome:R-HSA-8850846
NTPDase1 hydrolyzes nucleoside triphosphates
Reactome:R-HSA-8851089
NTPDase2 hydrolyzes nucleoside triphosphates
Reactome:R-HSA-8851110
NTPDase3 hydrolyzes nucleoside triphosphates
Reactome:R-HSA-8851234
NTPDase4 hydrolyzes nucleoside triphosphates
Reactome:R-HSA-8851494
NTPDase7 hydrolyzes nucleoside triphosphates
Reactome:R-HSA-8851538
NTPDase8 hydrolyzes nucleoside triphosphates
NTPase activity
EC:3.6.1.15
nucleoside 5-triphosphatase activity
EC:3.6.1.15
nucleoside triphosphate hydrolase activity
EC:3.6.1.15
nucleoside triphosphate phosphohydrolase activity
EC:3.6.1.15
nucleoside-5-triphosphate phosphohydrolase activity
EC:3.6.1.15
unspecific diphosphate phosphohydrolase activity
EC:3.6.1.15
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.
nucleolus biogenesis
nucleolus assembly
biological_process
nucleologenesis
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.
GOC:jl
ISBN:0198506732
nucleolus assembly
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
GO:0016478
down regulation of protein biosynthetic process
down-regulation of protein biosynthetic process
downregulation of protein biosynthetic process
negative regulation of protein anabolism
negative regulation of protein biosynthesis
negative regulation of protein biosynthetic process
negative regulation of protein formation
negative regulation of protein synthesis
inhibition of protein biosynthetic process
biological_process
protein biosynthesis inhibitor activity
protein biosynthetic process inhibitor activity
negative regulation of translation
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
GOC:isa_complete
Any process that modulates the frequency, rate or extent of exocytosis.
biological_process
regulation of exocytosis
Any process that modulates the frequency, rate or extent of exocytosis.
GOC:go_curators
Any process in which mitochondrial RNA is transported to, or maintained in, a specific location.
establishment and maintenance of mitochondrial RNA localization
mitochondrial RNA localisation
mtRNA localization
biological_process
mitochondrial RNA localization
Any process in which mitochondrial RNA is transported to, or maintained in, a specific location.
GOC:ai
mitochondrial RNA localisation
GOC:mah
Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
molecular_function
kinase regulator activity
Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GOC:ai
Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
molecular_function
phosphatase regulator activity
Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
GOC:ai
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
regulation of lipid metabolism
biological_process
regulation of lipid metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
GOC:go_curators
Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
biological_process
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
regulation of nucleobase-containing compound metabolic process
Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:go_curators
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
regulation of phosphate metabolism
biological_process
regulation of phosphate metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GOC:go_curators
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0044246
regulation of metabolism
regulation of multicellular organismal metabolic process
regulation of organismal metabolic process
biological_process
regulation of metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GOC:go_curators
regulation of organismal metabolic process
GOC:tb
The chemical reactions and pathways involving a protein. Includes protein modification.
GO:0006411
GO:0044268
Wikipedia:Protein_metabolism
protein metabolic process and modification
protein metabolism
protein metabolism and modification
multicellular organismal protein metabolic process
biological_process
protein metabolic process
The chemical reactions and pathways involving a protein. Includes protein modification.
GOC:ma
Any process involved in the maintenance of an internal steady state at the level of the cell.
biological_process
cellular homeostasis
Any process involved in the maintenance of an internal steady state at the level of the cell.
GOC:isa_complete
GOC:jl
ISBN:0395825172
The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
Wikipedia:Secondary_metabolism
secondary metabolism
secondary metabolite metabolic process
secondary metabolite metabolism
biological_process
secondary metabolic process
The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
GOC:go_curators
The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
carboxylic acid metabolism
biological_process
carboxylic acid metabolic process
The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
ISBN:0198506732
The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome.
biological_process
vesicle fusion with peroxisome
The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome.
GOC:jid
Interacting selectively and non-covalently with ribosomal RNA.
GO:0000944
base pairing with rRNA
molecular_function
rRNA binding
Interacting selectively and non-covalently with ribosomal RNA.
GOC:jl
Interacting selectively and non-covalently with any enzyme.
molecular_function
enzyme binding
Interacting selectively and non-covalently with any enzyme.
GOC:jl
Interacting selectively and non-covalently with any phosphatase.
molecular_function
phosphatase binding
Interacting selectively and non-covalently with any phosphatase.
GOC:jl
A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.
biological_process
developmental maturation
A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.
GOC:cls
GOC:dgh
GOC:dph
GOC:jid
GO_REF:0000021
The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.
biological_process
cell cycle process
The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.
GOC:isa_complete
GOC:mtg_cell_cycle
The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.
membrane docking
biological_process
membrane docking
The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.
GOC:isa_complete
PMID:27875684
A cellular process that results in the breakdown of a cellular component.
GO:0071845
cell structure disassembly
cellular component disassembly at cellular level
biological_process
cellular component disassembly
A cellular process that results in the breakdown of a cellular component.
GOC:isa_complete
A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
janelomax
2012-09-19T15:56:06Z
GO:0044702
biological_process
single organism reproductive process
reproductive process
A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
GOC:dph
GOC:isa_complete
Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.
regulation of morphogenesis
biological_process
regulation of anatomical structure morphogenesis
Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.
GOC:mah
Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.
biological_process
negative regulation of cell shape and cell size
positive regulation of cell shape and cell size
regulation of cell shape and cell size
regulation of cell morphogenesis
Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.
GOC:isa_complete
negative regulation of cell shape and cell size
GOC:dph
GOC:tb
positive regulation of cell shape and cell size
GOC:dph
GOC:tb
regulation of cell shape and cell size
GOC:dph
GOC:tb
The aggregation, arrangement and bonding together of a cellular component.
GO:0071844
cell structure assembly
cellular component assembly at cellular level
biological_process
cellular component assembly
The aggregation, arrangement and bonding together of a cellular component.
GOC:isa_complete
The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions.
biological_process
biological adhesion
The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions.
GOC:isa_complete
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.
RNA-protein complex biogenesis
ribonucleoprotein complex biogenesis and assembly
biological_process
ribonucleoprotein complex biogenesis
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.
GOC:isa_complete
GOC:mah
RNA-protein complex biogenesis
GOC:mah
ribonucleoprotein complex biogenesis and assembly
GOC:mah
A process that results in the breakdown of the extracellular matrix.
biological_process
extracellular matrix disassembly
A process that results in the breakdown of the extracellular matrix.
GOC:jid
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.
RNA-protein complex assembly
RNP complex assembly
protein-RNA complex assembly
biological_process
ribonucleoprotein complex assembly
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.
GOC:jl
A ribosome located in the cytosol.
GO:0005830
GO:0009281
GO:0030871
70S ribosome
80S ribosome
cellular_component
cytosolic ribosome
A ribosome located in the cytosol.
GOC:mtg_sensu
Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
active carrier activity
carrier activity
permease activity
pump activity
molecular_function
active transmembrane transporter activity
Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
GOC:mtg_transport
ISBN:0815340729
Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.
molecular_function
active ion transmembrane transporter activity
Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.
GOC:mtg_transport
ISBN:0815340729
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
GO:0005386
GO:0015563
GO:0015646
GO:0022891
GO:0022892
Reactome:R-HSA-1236947
Reactome:R-HSA-429036
Reactome:R-HSA-5638209
Reactome:R-HSA-5671707
Reactome:R-HSA-6784434
Reactome:R-HSA-6784436
molecular_function
substrate-specific transmembrane transporter activity
substrate-specific transporter activity
uptake permease activity
uptake transmembrane transporter activity
transmembrane transporter activity
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
GOC:jid
GOC:mtg_transport
ISBN:0815340729
Reactome:R-HSA-1236947
Egress of internalized antigen to the cytosol via sec61
Reactome:R-HSA-429036
SLC2A9 transports Fru, Glc, urate
Reactome:R-HSA-5638209
Defective SLC2A9 does not transport Fru, Glc, urate
Reactome:R-HSA-5671707
Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA
Reactome:R-HSA-6784434
An unknown carrier transports cytosolic glyoxylate to the peroxisome
Reactome:R-HSA-6784436
An unknown carrier transports mitochondrial glyoxylate to the cytosol
Enables the transfer of a macromolecule from one side of a membrane to the other.
molecular_function
macromolecule transmembrane transporter activity
Enables the transfer of a macromolecule from one side of a membrane to the other.
GOC:mtg_transport
ISBN:0815340729
Any process that modulates the frequency, rate or extent of transmembrane transporter activity.
biological_process
regulation of transmembrane transporter activity
Any process that modulates the frequency, rate or extent of transmembrane transporter activity.
GOC:dph
GOC:mtg_cardio
GOC:mtg_transport
Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.
2010-02-16T09:30:50Z
biological_process
regulation of gene expression as a consequence of signal transmission
signal transduction involved in regulation of gene expression
Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.
GOC:mtg_signal
regulation of gene expression as a consequence of signal transmission
GOC:bf
Any process that modulates the frequency, rate or extent of a signaling process.
2010-02-16T09:30:50Z
biological_process
regulation of signaling process
regulation of signalling process
regulation of signaling
Any process that modulates the frequency, rate or extent of a signaling process.
GOC:mtg_signal
regulation of signaling process
GOC:bf
regulation of signalling process
GOC:mah
The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
janelomax
2010-02-16T09:30:50Z
GO:0023046
GO:0044700
biological signaling
signaling process
signalling
biological_process
signalling process
single organism signaling
Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change.
signaling
The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
GOC:mtg_signal
GOC:mtg_signaling_feb11
GOC:signaling
signalling process
GOC:mah
Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.
2010-02-16T09:30:50Z
positive regulation of signalling process
biological_process
positive regulation of signaling process
positive regulation of signaling
Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.
GOC:mtg_signal
positive regulation of signalling process
GOC:mah
positive regulation of signaling process
GOC:bf
Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.
2010-02-16T09:30:50Z
biological_process
negative regulation of signaling process
negative regulation of signalling process
negative regulation of signaling
Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.
GOC:mtg_signal
negative regulation of signaling process
GOC:bf
negative regulation of signalling process
GOC:mah
The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.
2010-02-16T09:30:50Z
signal secretion
biological_process
signal release
The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.
GOC:mtg_signal
signal secretion
GOC:bf
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
cell projection organisation
biological_process
cell projection organization and biogenesis
cell surface structure organization and biogenesis
cell projection organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
GOC:jl
GOC:mah
http://www.cogsci.princeton.edu/~wn/
cell projection organization and biogenesis
GOC:mah
cell surface structure organization and biogenesis
GOC:mah
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
formation of a cell surface projection
biological_process
cell projection biogenesis
cell projection assembly
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
GOC:jl
GOC:mah
http://www.cogsci.princeton.edu/~wn/
cell projection biogenesis
GOC:mah
A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.
Wikipedia:Cell_junction
cellular_component
cell junction
A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.
GOC:aruk
GOC:bc
GOC:mah
ISBN:0198506732
PMID:26820516
PMID:28096264
http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
Wikipedia:Cellular_differentiation
biological_process
cell differentiation
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
ISBN:0198506732
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
biological_process
cell adhesion receptor regulator activity
regulation of cell adhesion
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
GOC:mah
Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
regulation of peptidolysis
biological_process
regulation of proteolysis
Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
GOC:mah
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GO:0044254
Wikipedia:Protein_catabolism
protein breakdown
protein catabolism
protein degradation
multicellular organismal protein catabolic process
biological_process
pheromone catabolic process
pheromone catabolism
This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children.
protein catabolic process
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
extracellular matrix organisation
biological_process
extracellular matrix organization and biogenesis
extracellular matrix organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
GOC:mah
extracellular matrix organization and biogenesis
GOC:mah
Binds to and modulates the activity of an enzyme.
GO:0010576
catalytic regulator activity
enzyme modulator
metalloenzyme regulator activity
molecular_function
GO:0030234 is reserved for cases when the regulator directly interacts with the enzyme. When regulation of enzyme activity is achieved without enzyme binding, or when the mechanism of regulation is unknown, instead annotate to 'regulation of catalytic activity ; GO:0050790'.
enzyme regulator activity
Binds to and modulates the activity of an enzyme.
GOC:dph
GOC:mah
GOC:tb
catalytic regulator activity
GOC:dph
The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions.
peroxisome degradation
biological_process
pexophagy
autophagy of peroxisome
The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions.
GOC:autophagy
PMID:10547367
PMID:20083110
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
GO:0005529
sugar binding
molecular_function
selectin
carbohydrate binding
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
GOC:mah
A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.
cellular_component
The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'.
external encapsulating structure
A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.
GOC:go_curators
The controlled breakdown of any cell membrane in the context of a normal process such as autophagy.
membrane breakdown
membrane catabolism
membrane degradation
biological_process
membrane disassembly
The controlled breakdown of any cell membrane in the context of a normal process such as autophagy.
GOC:mah
The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.
GO:0000065
nuclear movement, microtubule-mediated
nucleus migration
microtubule cytoskeleton-dependent nuclear positioning
microtubule cytoskeleton-dependent nucleus positioning
microtubule-dependent nuclear positioning
microtubule-dependent nucleus positioning
microtubule-mediated nuclear migration
nuclear migration, microtubule-mediated
transport of nucleus by microtubules
transport of nucleus, microtubule-mediated
biological_process
nuclear migration along microtubule
The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.
GOC:mah
GOC:sgd_curators
The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.
molecular_function
tRNA
transfer RNA
Note that this term can be used in place of the obsolete term 'transfer RNA ; GO:0005563'.
triplet codon-amino acid adaptor activity
The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.
GOC:hjd
GOC:mtg_MIT_16mar07
ISBN:0198506732
Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.
molecular_function
Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.
RNA modification guide activity
Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.
GOC:mah
PMID:12457565
The binding activity of a protein that brings together another macromolecule in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.
https://github.com/geneontology/go-ontology/issues/18655
protein binding, bridging
protein-protein adaptor
molecular_function
protein-macromolecule adaptor activity
The binding activity of a protein that brings together another macromolecule in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.
GOC:bf
GOC:mah
GOC:vw
The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.
biological_process
cytoskeleton-dependent intracellular transport
The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.
GOC:mah
A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.
cellular_component
retromer complex
A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.
GOC:bf
PMID:26220253
PMID:27385586
PMID:9700157
The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.
protein dislocation from ER
protein retrotranslocation, ER to cytosol
retrograde protein transport, endoplasmic reticulum to cytosol
biological_process
retrograde protein transport, ER to cytosol
The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.
PMID:11994744
protein dislocation from ER
GOC:dph
GOC:krc
protein retrotranslocation, ER to cytosol
GOC:bf
A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.
intraflagellar transport complex
intraflagellar transport particle
cellular_component
IFT complex
Note that we deem cilia and microtubule-based flagella to be equivalent.
intraciliary transport particle
A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.
GOC:cilia
GOC:kmv
PMID:14570576
PMID:22118932
PMID:23945166
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
GO:0005578
NIF_Subcellular:nlx_subcell_20090513
Wikipedia:Extracellular_matrix
proteinaceous extracellular matrix
matrisome
cellular_component
extracellular matrix
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
GOC:BHF
GOC:mah
GOC:rph
NIF_Subcellular:nlx_subcell_20090513
PMID:21123617
PMID:28089324
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.
microtubule organising center organisation
biological_process
microtubule organizing center organization and biogenesis
microtubule organizing center organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.
GOC:dph
GOC:jl
GOC:mah
microtubule organizing center organization and biogenesis
GOC:mah
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
NIF_Subcellular:sao830981606
cellular_component
intracellular membrane
organelle membrane
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
GOC:dos
GOC:mah
intracellular membrane
NIF_Subcellular:sao830981606
Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.
biological_process
microtubule polymerization or depolymerization
Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.
GOC:mah
Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.
biological_process
regulation of microtubule polymerization or depolymerization
Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.
down regulation of microtubule polymerization or depolymerization
down-regulation of microtubule polymerization or depolymerization
downregulation of microtubule polymerization or depolymerization
inhibition of microtubule polymerization or depolymerization
biological_process
negative regulation of microtubule polymerization or depolymerization
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.
GOC:mah
Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization.
up regulation of microtubule polymerization or depolymerization
up-regulation of microtubule polymerization or depolymerization
upregulation of microtubule polymerization or depolymerization
activation of microtubule polymerization or depolymerization
stimulation of microtubule polymerization or depolymerization
biological_process
positive regulation of microtubule polymerization or depolymerization
Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization.
GOC:mah
Any process that modulates the frequency, rate or extent of microtubule polymerization.
biological_process
regulation of microtubule polymerization
Any process that modulates the frequency, rate or extent of microtubule polymerization.
GOC:mah
Any process that modulates the frequency, rate or extent of microtubule depolymerization.
regulation of microtubule disassembly
biological_process
regulation of microtubule depolymerization
Any process that modulates the frequency, rate or extent of microtubule depolymerization.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.
down regulation of microtubule polymerization
down-regulation of microtubule polymerization
downregulation of microtubule polymerization
inhibition of microtubule polymerization
biological_process
negative regulation of microtubule polymerization
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.
GOC:mah
Any process that activates or increases the frequency, rate or extent of microtubule polymerization.
up regulation of microtubule polymerization
up-regulation of microtubule polymerization
upregulation of microtubule polymerization
activation of microtubule polymerization
stimulation of microtubule polymerization
biological_process
positive regulation of microtubule polymerization
Any process that activates or increases the frequency, rate or extent of microtubule polymerization.
GOC:mah
Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.
microtubule destabilization
positive regulation of microtubule disassembly
up regulation of microtubule depolymerization
up-regulation of microtubule depolymerization
upregulation of microtubule depolymerization
activation of microtubule depolymerization
positive regulation of microtubule catastrophe
stimulation of microtubule depolymerization
biological_process
positive regulation of microtubule depolymerization
Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.
GOC:mah
positive regulation of microtubule catastrophe
GOC:dph
GOC:tb
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
cytoplasmic microtubule organisation
biological_process
cytoplasmic microtubule organization and biogenesis
cytoplasmic microtubule organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
GOC:mah
cytoplasmic microtubule organization and biogenesis
GOC:mah
Any process in which the proteasome is transported to, or maintained in, a specific location.
establishment and maintenance of proteasome localization
proteasome localisation
biological_process
proteasome localization
Any process in which the proteasome is transported to, or maintained in, a specific location.
GOC:mah
proteasome localisation
GOC:mah
The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.
intrinsic to membrane
cellular_component
Note that proteins intrinsic to membranes cannot be removed without disrupting the membrane, e.g. by detergent.
intrinsic component of membrane
The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.
GOC:mah
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
intrinsic to plasma membrane
cellular_component
intrinsic component of plasma membrane
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
GOC:dos
GOC:mah
Catalysis of the reaction: ATP + H2O + amine(out) = ADP + phosphate + amine(in).
ATP-dependent amine transporter activity
amine-transporting ATPase activity
amine ABC transporter
molecular_function
ATPase-coupled amine transporter activity
Catalysis of the reaction: ATP + H2O + amine(out) = ADP + phosphate + amine(in).
GOC:mlg
The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
intrinsic to organelle membrane
cellular_component
intrinsic component of organelle membrane
The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
GOC:dos
GOC:mah
The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
integral to organelle membrane
cellular_component
integral component of organelle membrane
The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GOC:dos
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
regulation of cellular metabolism
biological_process
regulation of cellular metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
down regulation of cellular metabolic process
down-regulation of cellular metabolic process
downregulation of cellular metabolic process
negative regulation of cellular metabolism
inhibition of cellular metabolic process
biological_process
negative regulation of cellular metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
positive regulation of cellular metabolism
up regulation of cellular metabolic process
up-regulation of cellular metabolic process
upregulation of cellular metabolic process
activation of cellular metabolic process
stimulation of cellular metabolic process
biological_process
positive regulation of cellular metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
regulation of cellular anabolism
regulation of cellular biosynthesis
regulation of cellular formation
regulation of cellular synthesis
biological_process
regulation of cellular biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
down regulation of cellular biosynthetic process
down-regulation of cellular biosynthetic process
downregulation of cellular biosynthetic process
negative regulation of cellular anabolism
negative regulation of cellular biosynthesis
negative regulation of cellular formation
negative regulation of cellular synthesis
inhibition of cellular biosynthetic process
biological_process
negative regulation of cellular biosynthetic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
positive regulation of cellular anabolism
positive regulation of cellular biosynthesis
positive regulation of cellular formation
positive regulation of cellular synthesis
up regulation of cellular biosynthetic process
up-regulation of cellular biosynthetic process
upregulation of cellular biosynthetic process
activation of cellular biosynthetic process
stimulation of cellular biosynthetic process
biological_process
positive regulation of cellular biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
regulation of cellular breakdown
regulation of cellular catabolism
regulation of cellular degradation
biological_process
regulation of cellular catabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
down regulation of cellular catabolic process
down-regulation of cellular catabolic process
downregulation of cellular catabolic process
negative regulation of cellular breakdown
negative regulation of cellular catabolism
negative regulation of cellular degradation
inhibition of cellular catabolic process
biological_process
negative regulation of cellular catabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
positive regulation of cellular breakdown
positive regulation of cellular catabolism
positive regulation of cellular degradation
up regulation of cellular catabolic process
up-regulation of cellular catabolic process
upregulation of cellular catabolic process
activation of cellular catabolic process
stimulation of cellular catabolic process
biological_process
positive regulation of cellular catabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
down regulation of protein complex assembly
down-regulation of protein complex assembly
downregulation of protein complex assembly
inhibition of protein complex assembly
biological_process
negative regulation of protein complex assembly
negative regulation of protein-containing complex assembly
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
GOC:mah
Any process that activates or increases the frequency, rate or extent of protein complex assembly.
up regulation of protein complex assembly
up-regulation of protein complex assembly
upregulation of protein complex assembly
activation of protein complex assembly
stimulation of protein complex assembly
biological_process
positive regulation of protein complex assembly
positive regulation of protein-containing complex assembly
Any process that activates or increases the frequency, rate or extent of protein complex assembly.
GOC:mah
Any process that modulates the frequency, rate or extent of vesicle fusion.
biological_process
regulation of vesicle fusion
Any process that modulates the frequency, rate or extent of vesicle fusion.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.
down regulation of vesicle fusion
down-regulation of vesicle fusion
downregulation of vesicle fusion
inhibition of vesicle fusion
biological_process
negative regulation of vesicle fusion
Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.
GOC:mah
Any process that activates or increases the frequency, rate or extent of vesicle fusion.
up regulation of vesicle fusion
up-regulation of vesicle fusion
upregulation of vesicle fusion
activation of vesicle fusion
stimulation of vesicle fusion
biological_process
positive regulation of vesicle fusion
Any process that activates or increases the frequency, rate or extent of vesicle fusion.
GOC:mah
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
regulation of cell projection organisation
biological_process
regulation of cell projection organization and biogenesis
regulation of cell projection organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
GOC:mah
regulation of cell projection organization and biogenesis
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
down regulation of cell projection organization
down-regulation of cell projection organization
downregulation of cell projection organization
negative regulation of cell projection organisation
inhibition of cell projection organization
biological_process
negative regulation of cell projection organization and biogenesis
negative regulation of cell projection organization
Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
GOC:mah
down regulation of cell projection organization
GOC:mah
negative regulation of cell projection organization and biogenesis
GOC:mah
Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
positive regulation of cell projection organisation
up regulation of cell projection organization
up-regulation of cell projection organization
upregulation of cell projection organization
activation of cell projection organization
stimulation of cell projection organization
biological_process
positive regulation of cell projection organization and biogenesis
positive regulation of cell projection organization
Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
GOC:mah
positive regulation of cell projection organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
biological_process
regulation of protein modification process
Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
GOC:mah
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
down regulation of protein modification
down-regulation of protein modification
downregulation of protein modification
inhibition of protein modification
biological_process
negative regulation of protein modification process
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
GOC:mah
GOC:tb
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
up regulation of protein modification
up-regulation of protein modification
upregulation of protein modification
activation of protein modification
stimulation of protein modification
biological_process
positive regulation of protein modification process
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
GOC:mah
GOC:tb
Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
molecular_function
carboxylic acid binding
Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
GOC:mah
ISBN:0198506732
A vesicle found in the cytoplasm of a cell.
GO:0016023
NIF_Subcellular:sao180601769
cellular_component
cytoplasmic membrane bounded vesicle
cytoplasmic membrane-enclosed vesicle
cytoplasmic, membrane-bounded vesicle
cytoplasmic vesicle
A vesicle found in the cytoplasm of a cell.
GOC:ai
GOC:mah
GOC:vesicles
Any process that modulates the frequency, rate or extent of mRNA cleavage, any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
biological_process
regulation of mRNA cleavage
Any process that modulates the frequency, rate or extent of mRNA cleavage, any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA cleavage.
down regulation of mRNA cleavage
down-regulation of mRNA cleavage
downregulation of mRNA cleavage
inhibition of mRNA cleavage
biological_process
negative regulation of mRNA cleavage
Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA cleavage.
GOC:mah
Any process that activates or increases the frequency, rate or extent of mRNA cleavage.
up regulation of mRNA cleavage
up-regulation of mRNA cleavage
upregulation of mRNA cleavage
activation of mRNA cleavage
stimulation of mRNA cleavage
biological_process
positive regulation of mRNA cleavage
Any process that activates or increases the frequency, rate or extent of mRNA cleavage.
GOC:mah
A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.
establishment and maintenance of protein complex localization
protein complex localisation
biological_process
protein complex localization
protein-containing complex localization
A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.
GOC:mah
protein complex localisation
GOC:mah
A proteasome found in the nucleus of a cell.
cellular_component
nuclear proteasome complex
A proteasome found in the nucleus of a cell.
GOC:mah
Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.
regulation of neurological process
regulation of neurological system process
regulation of neurophysiological process
biological_process
regulation of nervous system process
Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.
GOC:dph
GOC:mah
GOC:tb
regulation of neurological process
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.
down regulation of neurological process
down-regulation of neurological process
downregulation of neurological process
negative regulation of neurological process
negative regulation of neurological system process
negative regulation of neurophysiological process
inhibition of neurological process
biological_process
negative regulation of nervous system process
Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.
GOC:dph
GOC:mah
GOC:tb
negative regulation of neurological process
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of a neurophysiological process.
positive regulation of neurological process
positive regulation of neurological system process
positive regulation of neurophysiological process
up regulation of neurological process
up-regulation of neurological process
upregulation of neurological process
activation of neurological process
stimulation of neurological process
biological_process
positive regulation of nervous system process
Any process that activates or increases the frequency, rate or extent of a neurophysiological process.
GOC:dph
GOC:mah
GOC:tb
positive regulation of neurological process
GOC:dph
GOC:tb
The directed movement of a lipid droplet along a microtubule, mediated by motor proteins.
adiposome transport along microtubule
lipid body transport along microtubule
lipid particle transport along microtubule
biological_process
lipid droplet transport along microtubule
The directed movement of a lipid droplet along a microtubule, mediated by motor proteins.
PMID:9491895
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
cellular_component
organelle envelope
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
GOC:mah
GOC:pz
The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
cellular_component
membrane-enclosed lumen
The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
GOC:add
GOC:mah
A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.
cellular_component
envelope
A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.
GOC:mah
GOC:pz
Any thylakoid within a plastid.
cellular_component
plastid thylakoid
Any thylakoid within a plastid.
GOC:pz
The volume enclosed by the nuclear inner membrane.
cellular_component
nuclear lumen
The volume enclosed by the nuclear inner membrane.
GOC:mah
GOC:pz
Any small, fluid-filled, spherical organelle enclosed by membrane.
GO:0031988
NIF_Subcellular:sao221389602
Wikipedia:Vesicle_(biology)
cellular_component
membrane-bounded vesicle
membrane-enclosed vesicle
vesicle
Any small, fluid-filled, spherical organelle enclosed by membrane.
GOC:mah
GOC:pz
GOC:vesicles
A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle.
suborganelle compartment
cellular_component
Note that this term refers to membrane-bounded compartments that are not considered organelles in their own right, but form parts of larger organelles.
organelle subcompartment
A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle.
GOC:mah
GOC:pz
The chemical reactions and pathways involving mitochondrial DNA.
mitochondrial DNA metabolism
mtDNA metabolic process
mtDNA metabolism
biological_process
mitochondrial DNA metabolic process
The chemical reactions and pathways involving mitochondrial DNA.
GOC:mah
The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA.
mitochondrial DNA breakdown
mitochondrial DNA catabolism
mitochondrial DNA degradation
mtDNA breakdown
mtDNA catabolic process
mtDNA catabolism
mtDNA degradation
biological_process
mitochondrial DNA catabolic process
The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA.
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).
microtubule basal body organisation
microtubule basal body organization
biological_process
microtubule basal body organization and biogenesis
ciliary basal body organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).
GOC:cilia
GOC:dph
GOC:jl
GOC:krc
GOC:mah
PMID:9889124
microtubule basal body organisation
GOC:mah
microtubule basal body organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
biological_process
nuclease regulator activity
regulation of nuclease activity
Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
GOC:mah
Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
biological_process
DNase regulator
deoxyribonuclease regulator
regulation of deoxyribonuclease activity
Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
GOC:mah
Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
down regulation of nuclease activity
down-regulation of nuclease activity
downregulation of nuclease activity
inhibition of nuclease activity
biological_process
nuclease inhibitor
negative regulation of nuclease activity
Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
GOC:mah
Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
up regulation of nuclease activity
up-regulation of nuclease activity
upregulation of nuclease activity
activation of nuclease activity
stimulation of nuclease activity
biological_process
nuclease activator
positive regulation of nuclease activity
Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
GOC:mah
Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
down regulation of deoxyribonuclease activity
down-regulation of deoxyribonuclease activity
downregulation of deoxyribonuclease activity
inhibition of deoxyribonuclease activity
biological_process
DNase inhibitor
deoxyribonuclease inhibitor
negative regulation of deoxyribonuclease activity
Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
GOC:mah
Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
up regulation of deoxyribonuclease activity
up-regulation of deoxyribonuclease activity
upregulation of deoxyribonuclease activity
activation of deoxyribonuclease activity
stimulation of deoxyribonuclease activity
biological_process
DNase activator
deoxyribonuclease activator
positive regulation of deoxyribonuclease activity
Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
down regulation of protein binding
down-regulation of protein binding
downregulation of protein binding
inhibition of protein binding
biological_process
negative regulation of protein binding
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
GOC:mah
Any process that activates or increases the frequency, rate or extent of protein binding.
up regulation of protein binding
up-regulation of protein binding
upregulation of protein binding
activation of protein binding
stimulation of protein binding
biological_process
positive regulation of protein binding
Any process that activates or increases the frequency, rate or extent of protein binding.
GOC:mah
Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein.
small conjugating protein binding
molecular_function
ubiquitin-like protein binding
Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein.
GOC:mah
small conjugating protein binding
GOC:dph
Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.
Wikipedia:Transposon
biological_process
transposition
Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.
GOC:jp
ISBN:1555812090
Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
regulation of nucleobase-containing compound transport
Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport
biological_process
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
negative regulation of nucleobase-containing compound transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
activation of nucleobase, nucleoside, nucleotide and nucleic acid transport
stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
biological_process
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
positive regulation of nucleobase-containing compound transport
Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
regulation of cellular protein metabolism
biological_process
regulation of cellular protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
down regulation of cellular protein metabolic process
down-regulation of cellular protein metabolic process
downregulation of cellular protein metabolic process
negative regulation of cellular protein metabolism
inhibition of cellular protein metabolic process
biological_process
negative regulation of cellular protein metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
positive regulation of cellular protein metabolism
up regulation of cellular protein metabolic process
up-regulation of cellular protein metabolic process
upregulation of cellular protein metabolic process
activation of cellular protein metabolic process
stimulation of cellular protein metabolic process
biological_process
positive regulation of cellular protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
GOC:mah
Any process that modulates the frequency, rate or extent of the process of creating protein polymers.
regulation of protein polymerisation
biological_process
regulation of protein polymerization
Any process that modulates the frequency, rate or extent of the process of creating protein polymers.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.
down regulation of protein polymerization
down-regulation of protein polymerization
downregulation of protein polymerization
inhibition of protein polymerization
biological_process
negative regulation of protein polymerization
Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.
up regulation of protein polymerization
up-regulation of protein polymerization
upregulation of protein polymerization
activation of protein polymerization
stimulation of protein polymerization
biological_process
positive regulation of protein polymerization
Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.
GOC:mah
The directed movement of lipids within cells.
biological_process
intracellular lipid transport
The directed movement of lipids within cells.
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
regulation of lipid transport
Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of lipid transport
down-regulation of lipid transport
downregulation of lipid transport
inhibition of lipid transport
biological_process
negative regulation of lipid transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of lipid transport
up-regulation of lipid transport
upregulation of lipid transport
activation of lipid transport
stimulation of lipid transport
biological_process
positive regulation of lipid transport
Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.
biological_process
regulation of intracellular lipid transport
Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.
down regulation of intracellular lipid transport
down-regulation of intracellular lipid transport
downregulation of intracellular lipid transport
inhibition of intracellular lipid transport
biological_process
negative regulation of intracellular lipid transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.
up regulation of intracellular lipid transport
up-regulation of intracellular lipid transport
upregulation of intracellular lipid transport
activation of intracellular lipid transport
stimulation of intracellular lipid transport
biological_process
positive regulation of intracellular lipid transport
Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.
biological_process
regulation of intracellular transport
Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.
down regulation of intracellular transport
down-regulation of intracellular transport
downregulation of intracellular transport
inhibition of intracellular transport
biological_process
negative regulation of intracellular transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.
up regulation of intracellular transport
up-regulation of intracellular transport
upregulation of intracellular transport
activation of intracellular transport
stimulation of intracellular transport
biological_process
positive regulation of intracellular transport
Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.
GOC:mah
Any process that modulates the activity of a transporter.
biological_process
regulation of transporter activity
Any process that modulates the activity of a transporter.
GOC:mah
Any process that stops or reduces the activity of a transporter.
down regulation of transporter activity
down-regulation of transporter activity
downregulation of transporter activity
inhibition of transporter activity
biological_process
negative regulation of transporter activity
Any process that stops or reduces the activity of a transporter.
GOC:mah
Any process that activates or increases the activity of a transporter.
up regulation of transporter activity
up-regulation of transporter activity
upregulation of transporter activity
activation of transporter activity
stimulation of transporter activity
biological_process
positive regulation of transporter activity
Any process that activates or increases the activity of a transporter.
GOC:mah
Any process that modulates the activity of an ion transporter.
regulation of ion transporter activity
biological_process
regulation of ion transmembrane transporter activity
Any process that modulates the activity of an ion transporter.
GOC:mah
GOC:tb
regulation of ion transporter activity
GOC:tb
Any process that stops or reduces the activity of an ion transporter.
down regulation of ion transporter activity
down-regulation of ion transporter activity
downregulation of ion transporter activity
negative regulation of ion transporter activity
inhibition of ion transporter activity
biological_process
negative regulation of ion transmembrane transporter activity
Any process that stops or reduces the activity of an ion transporter.
GOC:mah
GOC:tb
negative regulation of ion transporter activity
GOC:tb
Any process that activates or increases the activity of an ion transporter.
positive regulation of ion transporter activity
up regulation of ion transporter activity
up-regulation of ion transporter activity
upregulation of ion transporter activity
activation of ion transporter activity
stimulation of ion transporter activity
biological_process
positive regulation of ion transmembrane transporter activity
Any process that activates or increases the activity of an ion transporter.
GOC:mah
GOC:tb
positive regulation of ion transporter activity
GOC:tb
Any process in which a lysosome is transported to, and/or maintained in, a specific location.
lysosome localisation
biological_process
lysosome localization
Any process in which a lysosome is transported to, and/or maintained in, a specific location.
GOC:mah
lysosome localisation
GOC:mah
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
janelomax
2012-09-19T16:07:47Z
GO:0044707
GO:0050874
organismal physiological process
biological_process
single-multicellular organism process
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GOC:curators
GOC:dph
GOC:isa_complete
GOC:tb
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
janelomax
2012-12-19T12:21:31Z
GO:0044767
development
biological_process
single-organism developmental process
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GOC:isa_complete
The directed movement of proteins from the endoplasmic reticulum.
protein exit from ER
protein export from ER
protein export from endoplasmic reticulum
biological_process
protein exit from endoplasmic reticulum
The directed movement of proteins from the endoplasmic reticulum.
GOC:rb
protein export from ER
GOC:mah
protein export from endoplasmic reticulum
GOC:mah
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
mitochondrial protein anabolism
mitochondrial protein biosynthesis
mitochondrial protein formation
mitochondrial protein synthesis
mitochondrial protein translation
biological_process
mitochondrial translation
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
GOC:go_curators
The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
plastid protein anabolism
plastid protein biosynthesis
plastid protein formation
plastid protein synthesis
plastid protein translation
biological_process
plastid translation
The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
GOC:go_curators
The directed movement of a protein from one location to another within a lipid bilayer.
protein translocation within membrane
receptor translocation within membrane
receptor transport within lipid bilayer
biological_process
protein transport within lipid bilayer
The directed movement of a protein from one location to another within a lipid bilayer.
GOC:mah
The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.
RNA anabolism
RNA biosynthesis
RNA formation
RNA synthesis
biological_process
Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study.
RNA biosynthetic process
The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.
GOC:mah
GOC:txnOH
Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.
down regulation of ATPase activity
down-regulation of ATPase activity
downregulation of ATPase activity
negative regulation of adenosinetriphosphatase activity
inhibition of ATPase activity
biological_process
negative regulation of ATPase activity
Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.
GOC:mah
Any process that activates or increases the rate of ATP hydrolysis by an ATPase.
positive regulation of adenosinetriphosphatase activity
up regulation of ATPase activity
up-regulation of ATPase activity
upregulation of ATPase activity
activation of ATPase activity
stimulation of ATPase activity
biological_process
positive regulation of ATPase activity
Any process that activates or increases the rate of ATP hydrolysis by an ATPase.
GOC:mah
The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
ribosome recycling
biological_process
ribosome dissociation factor
ribosome disassembly
The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
GOC:mah
GOC:vk
ribosome recycling
GOC:db
PMID:9463391
All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.
cellular_component
plasma membrane bounded cell projection cytoplasm
All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.
GOC:krc
GOC:mah
Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.
biological_process
regulation of karyogamy
Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.
GOC:mah
Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
regulation of localisation
biological_process
regulation of localization
Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
GOC:mah
regulation of localisation
GOC:mah
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
regulation of protein localisation
biological_process
regulation of protein localization
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
GOC:dph
GOC:mah
GOC:tb
regulation of protein localisation
GOC:mah
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.
biological_process
regulation of microtubule-based process
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
regulation of organic acid transport
Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of organic acid transport
down-regulation of organic acid transport
downregulation of organic acid transport
inhibition of organic acid transport
biological_process
negative regulation of organic acid transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of organic acid transport
up-regulation of organic acid transport
upregulation of organic acid transport
activation of organic acid transport
stimulation of organic acid transport
biological_process
positive regulation of organic acid transport
Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
The controlled release of a substance by a cell.
Wikipedia:Secretion
cellular secretion
biological_process
secretion by cell
The controlled release of a substance by a cell.
GOC:mah
The disaggregation of a protein-containing macromolecular complex into its constituent components.
GO:0034623
GO:0043241
protein complex disassembly
biological_process
cellular macromolecule complex disassembly
macromolecule complex disassembly
protein-containing complex disassembly
The disaggregation of a protein-containing macromolecular complex into its constituent components.
GOC:mah
The disaggregation of a protein-RNA complex into its constituent components.
RNA-protein complex disassembly
RNP complex disassembly
protein-RNA complex disassembly
biological_process
ribonucleoprotein complex disassembly
The disaggregation of a protein-RNA complex into its constituent components.
GOC:mah
The process in which cellular structures, including whole cells or cell parts, are generated and organized.
cellular structure morphogenesis
biological_process
cellular component morphogenesis
The process in which cellular structures, including whole cells or cell parts, are generated and organized.
GOC:dph
GOC:mah
GOC:tb
cellular structure morphogenesis
GOC:dph
GOC:tb
The process in which the anatomical structures of a cell part are generated and organized.
biological_process
cell part morphogenesis
The process in which the anatomical structures of a cell part are generated and organized.
GOC:mah
Any process in which a macromolecule is transported to, or maintained in, a specific location.
macromolecule localisation
biological_process
macromolecule localization
Any process in which a macromolecule is transported to, or maintained in, a specific location.
GOC:mah
macromolecule localisation
GOC:mah
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
regulation of organelle organisation
biological_process
regulation of organelle organization and biogenesis
regulation of organelle organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
GOC:mah
regulation of organelle organisation
GOC:mah
regulation of organelle organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.
regulation of chromosome organisation
biological_process
regulation of chromosome organization and biogenesis
regulation of chromosome organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.
GOC:mah
regulation of chromosome organisation
GOC:mah
regulation of chromosome organization and biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.
biological_process
regulation of intracellular protein transport
Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.
regulation of amine metabolism
biological_process
regulation of cellular amine metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.
negative regulation of amine metabolism
biological_process
negative regulation of cellular amine metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.
positive regulation of amine metabolism
biological_process
positive regulation of cellular amine metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
regulation of amine breakdown
regulation of amine catabolism
regulation of amine degradation
biological_process
regulation of cellular amine catabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
negative regulation of amine breakdown
negative regulation of amine catabolism
negative regulation of amine degradation
biological_process
negative regulation of cellular amine catabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
positive regulation of amine breakdown
positive regulation of amine catabolism
positive regulation of amine degradation
biological_process
positive regulation of cellular amine catabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
GOC:mah
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out).
ATP-dependent organic acid transmembrane transporter activity
organic acid-transporting ATPase activity
molecular_function
ATPase-coupled organic acid transmembrane transporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out).
GOC:mlg
A process in which a protein is transported to, or maintained in, a location within an organelle.
protein localisation to organelle
protein localization in organelle
biological_process
protein localization to organelle
A process in which a protein is transported to, or maintained in, a location within an organelle.
GOC:mah
protein localisation to organelle
GOC:mah
protein localization in organelle
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
biological_process
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to stress
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
down regulation of kinase activity
down-regulation of kinase activity
downregulation of kinase activity
inhibition of kinase activity
kinase inhibitor
biological_process
negative regulation of kinase activity
Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GOC:mah
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
up regulation of kinase activity
up-regulation of kinase activity
upregulation of kinase activity
kinase activator
stimulation of kinase activity
biological_process
positive regulation of kinase activity
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GOC:mah
A process in which a ribosome is transported to, and/or maintained in, a specific location.
GO:0033753
biological_process
establishment of ribosome localisation
establishment of ribosome localization
ribosome localisation
ribosome localization
A process in which a ribosome is transported to, and/or maintained in, a specific location.
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
biological_process
response to lipid
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
GOC:sl
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out).
lipid-transporting ATPase activity
ATP-dependent lipid transmembrane transporter activity
molecular_function
ATPase-coupled lipid transmembrane transporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out).
GOC:BHF
GOC:rl
A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.
midori
2011-02-14T02:26:36Z
GO:0000042
GO:0072600
protein localisation in Golgi apparatus
protein localization in Golgi apparatus
establishment of protein localisation to Golgi
establishment of protein localization in Golgi
establishment of protein localization to Golgi
establishment of protein localization to Golgi apparatus
biological_process
protein targeting to Golgi
protein-Golgi targeting
protein localization to Golgi apparatus
A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.
GOC:mah
protein localisation in Golgi apparatus
GOC:mah
establishment of protein localisation to Golgi
GOC:mah
establishment of protein localization to Golgi apparatus
GOC:mah
The process in which a carbohydrate is transported across a membrane.
carbohydrate membrane transport
transmembrane carbohydrate transport
biological_process
Note that this term is not intended for use in annotating lateral movement within membranes.
carbohydrate transmembrane transport
The process in which a carbohydrate is transported across a membrane.
GOC:mah
transmembrane carbohydrate transport
GOC:dph
GOC:tb
A process in which an ion is transported across a membrane.
GO:0099131
ion membrane transport
transmembrane ion transport
ATP hydrolysis coupled ion transmembrane transport
biological_process
Note that this term is not intended for use in annotating lateral movement within membranes.
ion transmembrane transport
A process in which an ion is transported across a membrane.
GOC:mah
transmembrane ion transport
GOC:dph
GOC:tb
Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
GO:0034259
GO:0034261
GO:1902264
GO:1902881
down regulation of GTPase activity
down-regulation of GTPase activity
downregulation of GTPase activity
negative regulation of guanosinetriphosphatase activity
down regulation of Rab GTPase activity
down regulation of Ras GTPase activity
down regulation of Rho GTPase activity
down regulation of regulation of Ran GTPase activity
down-regulation of Rab GTPase activity
down-regulation of Ras GTPase activity
down-regulation of Rho GTPase activity
down-regulation of regulation of Ran GTPase activity
downregulation of Rab GTPase activity
downregulation of Ras GTPase activity
downregulation of Rho GTPase activity
downregulation of regulation of Ran GTPase activity
inhibition of GTPase activity
inhibition of Rab GTPase activity
inhibition of Ras GTPase activity
inhibition of Rho GTPase activity
inhibition of regulation of Ran GTPase activity
negative regulation of Rab GTPase activity
negative regulation of Ran GTPase activity
negative regulation of Ras GTPase activity
negative regulation of Rho GTPase activity
biological_process
An example of this is P2xA in Dictyostelium (UniProt symbol Q86JM7) in PMID:24335649.
negative regulation of GTPase activity
Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
GOC:TermGenie
GOC:mah
GOC:rb
GO_REF:0000058
PMID:16143306
PMID:24335649
down regulation of Rab GTPase activity
GOC:pf
down regulation of regulation of Ran GTPase activity
GOC:TermGenie
down-regulation of Rab GTPase activity
GOC:pf
down-regulation of regulation of Ran GTPase activity
GOC:TermGenie
downregulation of Rab GTPase activity
GOC:pf
downregulation of regulation of Ran GTPase activity
GOC:TermGenie
inhibition of Rab GTPase activity
GOC:pf
inhibition of regulation of Ran GTPase activity
GOC:TermGenie
A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.
biological_process
cell junction assembly
A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.
cell junction assembly and maintenance
cell junction organisation
biological_process
cell junction biogenesis
cell junction organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.
GOC:dph
GOC:jl
GOC:mah
cell junction organisation
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.
https://github.com/geneontology/go-ontology/issues/13534
https://github.com/geneontology/go-ontology/issues/15963
lipid particle organization and biogenesis
adiposome organization
lipid body organization
lipid particle organisation
lipid particle organization
biological_process
lipid droplet organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.
GOC:dph
GOC:jl
GOC:mah
PMID:18093937
PMID:18250201
lipid particle organization and biogenesis
GOC:mah
Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules.
biological_process
ncRNA processing
Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules.
GOC:mah
The process in which a solute is transported from one side of the vacuolar membrane to the other.
vacuolar membrane transport
biological_process
Note that this term is not intended for use in annotating lateral movement within membranes.
vacuolar transmembrane transport
The process in which a solute is transported from one side of the vacuolar membrane to the other.
GOC:mah
Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.
protein localisation to chromosome
condensin localization to chromosome
biological_process
protein localization to chromosome
Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.
GOC:mah
protein localisation to chromosome
GOC:mah
A process in which a protein transports or maintains the localization of another protein to the nucleus.
2012-11-07T15:45:54Z
GO:0044744
protein localisation to nucleus
protein localization in cell nucleus
protein localization in nucleus
biological_process
protein targeting to nucleus
protein localization to nucleus
A process in which a protein transports or maintains the localization of another protein to the nucleus.
GOC:ecd
protein localisation to nucleus
GOC:mah
protein localization in nucleus
GOC:mah
Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GO:0016249
cellular protein localisation
channel localizer activity
biological_process
cellular protein localization
Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GOC:mah
cellular protein localisation
GOC:mah
channel localizer activity
GOC:mah
The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.
GO:0043623
cellular protein complex assembly
biological_process
cellular macromolecule complex assembly
cellular protein-containing complex assembly
The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.
GOC:jl
A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell.
cellular protein complex localisation
establishment and maintenance of cellular protein complex localization
biological_process
cellular protein complex localization
cellular protein-containing complex localization
A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell.
GOC:mah
cellular protein complex localisation
GOC:mah
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
cellular nitrogen compound metabolism
biological_process
cellular nitrogen compound metabolic process
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GOC:mah
The directed movement of the mitochondrion to a specific location, by a process involving microtubules.
establishment of mitochondrion localisation, microtubule-mediated
microtubule-mediated mitochondrion localization
mitochondrial localization, microtubule-mediated
biological_process
establishment of mitochondrion localization, microtubule-mediated
The directed movement of the mitochondrion to a specific location, by a process involving microtubules.
GOC:mah
PMID:12972644
PMID:15979253
PMID:16306220
establishment of mitochondrion localisation, microtubule-mediated
GOC:mah
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.
GO:0034961
cellular biopolymer biosynthetic process
cellular macromolecule anabolism
cellular macromolecule biosynthesis
cellular macromolecule formation
cellular macromolecule synthesis
biological_process
cellular macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.
GOC:mah
cellular biopolymer biosynthetic process
GOC:mtg_chebi_dec09
cellular macromolecule anabolism
GOC:mah
cellular macromolecule biosynthesis
GOC:mah
cellular macromolecule formation
GOC:mah
cellular macromolecule synthesis
GOC:mah
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
nucleobase, nucleoside, nucleotide and nucleic acid anabolism
nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis
nucleobase, nucleoside, nucleotide and nucleic acid formation
nucleobase, nucleoside, nucleotide and nucleic acid synthesis
biological_process
nucleobase-containing compound biosynthetic process
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:mah
The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.
nucleobase, nucleoside, nucleotide and nucleic acid breakdown
nucleobase, nucleoside, nucleotide and nucleic acid catabolism
nucleobase, nucleoside, nucleotide and nucleic acid degradation
biological_process
nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
nucleobase-containing compound catabolic process
The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:mah
nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
GOC:dph
GOC:tb
The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs).
ncRNA metabolism
biological_process
ncRNA metabolic process
The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs).
GOC:mah
The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs).
ncRNA breakdown
ncRNA catabolism
ncRNA degradation
biological_process
ncRNA catabolic process
The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs).
GOC:rb
PMID:18591258
A protein complex that possesses methyltransferase activity.
cellular_component
methyltransferase complex
A protein complex that possesses methyltransferase activity.
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
regulation of membrane transport
biological_process
regulation of transmembrane transport
Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
down regulation of transmembrane transport
down-regulation of transmembrane transport
downregulation of transmembrane transport
negative regulation of membrane transport
inhibition of transmembrane transport
biological_process
negative regulation of transmembrane transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
GOC:mah
Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
positive regulation of membrane transport
up regulation of transmembrane transport
up-regulation of transmembrane transport
upregulation of transmembrane transport
activation of transmembrane transport
stimulation of transmembrane transport
biological_process
positive regulation of transmembrane transport
Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
regulation of ion membrane transport
regulation of transmembrane ion transport
biological_process
regulation of ion transmembrane transport
Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
GOC:mah
regulation of transmembrane ion transport
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
down regulation of transmembrane ion transport
down-regulation of transmembrane ion transport
downregulation of transmembrane ion transport
negative regulation of ion membrane transport
negative regulation of transmembrane ion transport
inhibition of transmembrane ion transport
biological_process
negative regulation of ion transmembrane transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
GOC:mah
negative regulation of transmembrane ion transport
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
positive regulation of ion membrane transport
positive regulation of transmembrane ion transport
up regulation of transmembrane ion transport
up-regulation of transmembrane ion transport
upregulation of transmembrane ion transport
activation of transmembrane ion transport
stimulation of transmembrane ion transport
biological_process
positive regulation of ion transmembrane transport
Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
ER stress response
cellular response to endoplasmic reticulum stress
response to ER stress
biological_process
response to endoplasmic reticulum stress
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
GOC:cjm
GOC:mah
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
GO:0035083
GO:0035084
ciliary axoneme assembly
cilium axoneme assembly
flagellar axoneme assembly
flagellum axoneme assembly
biological_process
axoneme biogenesis
cilium axoneme biogenesis
Note that cilia and eukaryotic flagella are deemed to be equivalent.
axoneme assembly
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
GOC:bf
GOC:cilia
GOC:jl
ISBN:0815316194
axoneme biogenesis
GOC:mah
cilium axoneme biogenesis
GOC:mah
Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.
biological_process
regulation of dephosphorylation
Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.
GOC:bf
Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.
down regulation of dephosphorylation
down-regulation of dephosphorylation
downregulation of dephosphorylation
inhibition of dephosphorylation
biological_process
negative regulation of dephosphorylation
Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.
GOC:bf
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.
up regulation of dephosphorylation
up-regulation of dephosphorylation
upregulation of dephosphorylation
activation of dephosphorylation
stimulation of dephosphorylation
biological_process
positive regulation of dephosphorylation
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.
GOC:bf
A process in which a protein is transported to, or maintained at, a microtubule.
rfoulger
2010-03-11T11:00:56Z
protein localisation to microtubule
biological_process
protein localization to microtubule
A process in which a protein is transported to, or maintained at, a microtubule.
GOC:bf
GOC:lb
protein localisation to microtubule
GOC:mah
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
rfoulger
2010-05-14T01:14:37Z
GO:0007242
GO:0007243
GO:0023013
GO:0023034
intracellular signaling chain
intracellular protein kinase cascade
intracellular signal transduction pathway
protein kinase cascade
signal transmission via intracellular cascade
biological_process
intracellular signaling cascade
intracellular signaling pathway
signal transduction via intracellular signaling cascade
intracellular signal transduction
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
GOC:bf
GOC:jl
GOC:signaling
ISBN:3527303782
intracellular signaling chain
ISBN:3527303782
intracellular protein kinase cascade
GOC:signaling
protein kinase cascade
GOC:signaling
intracellular signaling cascade
GOC:signaling
The directed movement of a protein to a specific location within the extracellular region.
rfoulger
2010-11-09T10:25:08Z
establishment of protein localisation in extracellular region
establishment of protein localization in extracellular region
biological_process
establishment of protein localization to extracellular region
The directed movement of a protein to a specific location within the extracellular region.
GOC:BHF
GOC:bf
establishment of protein localisation in extracellular region
GOC:mah
The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.
rfoulger
2011-02-28T11:06:40Z
catabolism of mitochondrial protein
degradation of damaged mitochondrial protein
biological_process
mitochondrial protein catabolic process
The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.
GOC:sp
PMID:21264221
PMID:21264228
catabolism of mitochondrial protein
GOC:bf
degradation of damaged mitochondrial protein
GOC:bf
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
rfoulger
2011-03-17T10:55:42Z
intraflagellar transport
Reactome:R-HSA-5620924.2
biological_process
intraciliary transport involved in cilium morphogenesis
intraflagellar transport involved in cilium morphogenesis
intraciliary transport involved in cilium assembly
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
GOC:bf
GOC:cilia
Reactome:R-HSA-5620924.2
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
rfoulger
2011-05-25T03:09:58Z
cilial transition zone
cilium transition zone
cellular_component
connecting cilium
Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone.
ciliary transition zone
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
GOC:cilia
GOC:kmv
PMID:21422230
A process in which a protein is transported to, or maintained in, a location within an endosome.
rfoulger
2011-10-06T02:42:18Z
protein localisation in endosome
protein localization in endosome
biological_process
protein localization to endosome
A process in which a protein is transported to, or maintained in, a location within an endosome.
GOC:yaf
protein localisation in endosome
GOC:bf
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
rfoulger
2011-12-15T10:40:20Z
GO:0005932
basal body
NIF_Subcellular:sao11978067
cilial basal body
cilium basal body
microtubule basal body
cellular_component
In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.
ciliary basal body
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
GOC:cilia
GOC:clt
PMID:21750193
cilium basal body
GOC:bf
Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule.
rfoulger
2012-01-17T04:20:34Z
molecular_function
Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
small molecule binding
Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule.
GOC:curators
GOC:pde
GOC:pm
The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.
rfoulger
2012-04-24T04:48:48Z
histone protein catabolic process
biological_process
This term was created even though it describes a process relating to a group of gene products, because histones are highly conserved proteins that are essential components of cellular chromatin in eukaryotic cells.
histone catabolic process
The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.
GOC:krc
histone protein catabolic process
GOC:bf
GOC:jl
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
rfoulger
2012-04-26T01:47:12Z
protein modification
biological_process
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GOC:bf
GOC:jl
protein modification
GOC:bf
Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.
rfoulger
2013-08-12T11:38:20Z
ATPase involved in positive regulation of proteasomal protein catabolic process
proteasomal ATPase activity
proteasome channel gating activity
proteasome channel opening activity
molecular_function
proteasome-activating ATPase activity
Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.
GOC:rb
PMID:11430818
ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:bf
proteasomal ATPase activity
GOC:bf
proteasome channel gating activity
GOC:rb
proteasome channel opening activity
GOC:rb
The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
rebeccafoulger
2015-05-14T11:43:06Z
endoplasmic reticulum-associated degradation
protein degradation by ERAD
biological_process
ER-associated degradation pathway
endoplasmic reticulum-associated protein degradation pathway
ER-associated protein degradation (ERAD) pathways target misfolded ER lumenal proteins (ERAD-L), ER membrane proteins (ERAD-M), and ER proteins with misfolded cytosolic domains (ERAD-C) by recognizing aberrant proteins, retrotranslocating these substrates to the cytosol, followed by substrate ubiquitination and proteosomal-mediated degradation. In contrast the stress-induced homeostatically regulated protein degradation (SHRED) pathway (GO:0120174), although inducible by stress, targets diverse ER membrane, and cytosolic proteins as well as numerous other native proteins in the absence of stress. Stress results in the protease-mediated (Nma111p) generation of a Roq1p cleavage product that then binds to the type-1 active site of Ubr1p, altering its substrate specificity, and leading to the proteasome-mediated degradation of both misfolded and native proteins. Although the SHRED pathway may contain some components in common with ERAD pathways (GO:0036503), such as UBR1, RAD6 and CDC48, other ERAD components, such as HRD1 and DOA10, do not appear to be involved, and as such these pathways are currently considered to be distinct.
ERAD pathway
The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
GOC:PARL
GOC:bf
PMID:20940304
PMID:21969857
endoplasmic reticulum-associated degradation
PMID:22535891
protein degradation by ERAD
GOC:bf
ER-associated degradation pathway
PMID:24699081
endoplasmic reticulum-associated protein degradation pathway
GOC:bf
The increase in size or mass of an entire organism, a part of an organism or a cell.
GO:0048590
biological_process
growth pattern
non-developmental growth
See also the biological process term 'cell growth ; GO:0016049'.
growth
The increase in size or mass of an entire organism, a part of an organism or a cell.
GOC:bf
GOC:ma
non-developmental growth
GOC:mah
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
biological_process
regulation of growth
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
GOC:ems
GOC:mah
Self-propelled movement of a cell or organism from one location to another.
biological_process
locomotion
Self-propelled movement of a cell or organism from one location to another.
GOC:dgh
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
biological_process
regulation of locomotion
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
GOC:ems
Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.
down regulation of locomotion
down-regulation of locomotion
downregulation of locomotion
inhibition of locomotion
biological_process
negative regulation of locomotion
Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
up regulation of locomotion
up-regulation of locomotion
upregulation of locomotion
activation of locomotion
stimulation of locomotion
biological_process
positive regulation of locomotion
Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of embryonic development.
up regulation of embryonic development
up-regulation of embryonic development
upregulation of embryonic development
activation of embryonic development
stimulation of embryonic development
biological_process
positive regulation of embryonic development
Any process that activates or increases the frequency, rate or extent of embryonic development.
GOC:go_curators
Any process, mediated by small non-coding RNAs, that stops, prevents or reduces the rate that mRNAs are effectively translated into protein.
down regulation of mRNA translation, ncRNA-mediated
down-regulation of mRNA translation, ncRNA-mediated
downregulation of mRNA translation, ncRNA-mediated
inhibition of mRNA translation, ncRNA-mediated
biological_process
negative regulation of translation, ncRNA-mediated
Any process, mediated by small non-coding RNAs, that stops, prevents or reduces the rate that mRNAs are effectively translated into protein.
GOC:dph
GOC:ems
GOC:tb
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
GO:0035734
Wikipedia:Intraflagellar_transport
intraflagellar transport
intraflagellar transport involved in cilium organization
intraflagellar transport involved in microtubule-based flagellum organisation
biological_process
IFT
Note that we deem cilium and microtubule-based flagellum to be equivalent.
intraciliary transport
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
GOC:cilia
GOC:kmv
PMID:17981739
PMID:18180368
PMID:22869374
Reactome:R-HSA-5620924.2
Any process that modulates the frequency, rate or extent of cell proliferation.
biological_process
regulation of cell proliferation
regulation of cell population proliferation
Any process that modulates the frequency, rate or extent of cell proliferation.
GOC:jl
The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
retrograde (endosome to Golgi) transport
biological_process
retrograde transport, endosome to Golgi
The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
GOC:jl
PMID:10873832
PMID:16936697
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
regulation of protein breakdown
regulation of protein catabolism
regulation of protein degradation
biological_process
regulation of protein catabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GOC:go_curators
GOC:jl
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
down regulation of protein catabolic process
down-regulation of protein catabolic process
downregulation of protein catabolic process
negative regulation of protein breakdown
negative regulation of protein catabolism
negative regulation of protein degradation
inhibition of protein catabolic process
biological_process
negative regulation of protein catabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GOC:go_curators
GOC:jl
PMID:10207076
The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
ketone metabolism
biological_process
cellular ketone metabolic process
The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
GOC:jl
ISBN:0787650153
The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
ketone anabolism
ketone biosynthesis
ketone formation
ketone synthesis
biological_process
ketone biosynthetic process
The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
GOC:go_curators
The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
ketone breakdown
ketone catabolism
ketone degradation
biological_process
ketone catabolic process
The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
GOC:go_curators
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
response to chemical stimulus
response to chemical substance
biological_process
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to chemical
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GOC:jl
response to chemical stimulus
GOC:dos
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
GO:0007046
ribosome biogenesis and assembly
biological_process
ribosome biogenesis
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
GOC:ma
PMID:26404467
Wikipedia:Ribosome_biogenesis
The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
GO:0042257
ribosomal subunit assembly
biological_process
ribosome assembly
The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
GOC:ma
ribosomal subunit assembly
GOC:mah
GOC:vw
Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
biological_process
regulation of phosphorylation
Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
GOC:jl
Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.
down regulation of phosphorylation
down-regulation of phosphorylation
downregulation of phosphorylation
inhibition of phosphorylation
biological_process
negative regulation of phosphorylation
Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.
GOC:jl
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
up regulation of phosphorylation
up-regulation of phosphorylation
upregulation of phosphorylation
activation of phosphorylation
stimulation of phosphorylation
biological_process
positive regulation of phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
GOC:jl
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
molecular_function
histone-specific chaperone activity
histone binding
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
GOC:jl
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
cell wall assembly
biological_process
cell wall biogenesis
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GOC:jl
GOC:mah
GOC:mtg_sensu
ISBN:0198506732
Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
molecular_function
phosphoric ester hydrolase activity
Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
GOC:jl
Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).
Wikipedia:Microbody
cellular_component
microbody
Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).
ISBN:0198506732
Any biological process involved in the maintenance of an internal steady state.
GO:0032844
GO:0032845
GO:0032846
homeostasis
activation of homeostatic process
inhibition of homeostatic process
biological_process
negative regulation of homeostatic process
positive regulation of homeostatic process
regulation of homeostatic process
homeostatic process
Any biological process involved in the maintenance of an internal steady state.
GOC:jl
ISBN:0395825172
Enables the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate.
ATP-dependent ion transmembrane transporter activity
ATPase activity, coupled to transmembrane movement of ions
ATPase coupled ion transmembrane transporter activity
molecular_function
ATPase-coupled ion transmembrane transporter activity
Enables the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate.
GOC:jl
GOC:mtg_transport
ISBN:0815340729
Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.
https://github.com/geneontology/go-ontology/issues/14642
https://github.com/geneontology/go-ontology/issues/17373
GO:0015405
GO:0016820
P-P-bond-hydrolysis-driven transmembrane transporter activity
P-P-bond-hydrolysis-driven transporter
EC:7.2.2
Reactome:R-HSA-266070
Reactome:R-HSA-5223313
Reactome:R-HSA-5362459
Reactome:R-HSA-5387389
Reactome:R-HSA-5683325
ATP-coupled transmembrane transporter activity
ATP-dependent transmembrane transporter activity
ATPase activity, coupled to transmembrane movement of substances
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
molecular_function
ATPase-coupled transmembrane transporter activity
Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.
GOC:mtg_transport
ISBN:0815340729
Reactome:R-HSA-266070
LTC4 is exported from the cytosol by ABCC1
Reactome:R-HSA-5223313
ABCD4 may transport Cbl from lysosomal lumen to cytosol
Reactome:R-HSA-5362459
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol
Reactome:R-HSA-5387389
Hh processing variants are translocated to the cytosol in a VCP-dependent manner
Reactome:R-HSA-5683325
Defective ABCD4 does not transport Cbl from lysosomal lumen to cytosol
The region of a mitochondrion to which the DNA is confined.
cellular_component
mitochondrial nucleoid
The region of a mitochondrion to which the DNA is confined.
GOC:jl
The region of a plastid to which the DNA is confined.
cellular_component
plastid nucleoid
The region of a plastid to which the DNA is confined.
GOC:jl
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.
regulation of sulfur metabolism
regulation of sulphur metabolic process
regulation of sulphur metabolism
biological_process
regulation of sulfur metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.
GOC:go_curators
A prolongation or process extending from a cell, e.g. a flagellum or axon.
cell process
cellular process
cellular projection
cellular_component
cell projection
A prolongation or process extending from a cell, e.g. a flagellum or axon.
GOC:jl
http://www.cogsci.princeton.edu/~wn/
Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
biological_process
regulation of Golgi to plasma membrane protein transport
Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
GOC:jl
Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
down regulation of Golgi to plasma membrane protein transport
down-regulation of Golgi to plasma membrane protein transport
downregulation of Golgi to plasma membrane protein transport
inhibition of Golgi to plasma membrane protein transport
biological_process
negative regulation of Golgi to plasma membrane protein transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
GOC:jl
Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
up regulation of Golgi to plasma membrane protein transport
up-regulation of Golgi to plasma membrane protein transport
upregulation of Golgi to plasma membrane protein transport
activation of Golgi to plasma membrane protein transport
stimulation of Golgi to plasma membrane protein transport
biological_process
positive regulation of Golgi to plasma membrane protein transport
Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
GOC:jl
The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
biological_process
Golgi to plasma membrane protein transport
The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
ISBN:0716731363
Interacting selectively and non-covalently with any complex of RNA and protein.
RNP binding
protein-RNA complex binding
ribonucleoprotein binding
molecular_function
ribonucleoprotein complex binding
Interacting selectively and non-covalently with any complex of RNA and protein.
GOC:bf
GOC:go_curators
GOC:vk
protein-RNA complex binding
GOC:bf
GOC:vk
ribonucleoprotein binding
GOC:bf
GOC:vk
Interacting selectively and non-covalently with any part of a ribosome.
GO:0030376
ribosome receptor activity
molecular_function
ribosome binding
Interacting selectively and non-covalently with any part of a ribosome.
GOC:go_curators
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.
extracellular structure organisation
extracellular structure organization and biogenesis
biological_process
extracellular structure organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.
GOC:ai
GOC:dph
GOC:jl
GOC:mah
extracellular structure organization and biogenesis
GOC:dph
GOC:jl
GOC:mah
Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GO:0043070
regulation of non-apoptotic programmed cell death
biological_process
regulation of programmed cell death
Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GOC:jl
Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GO:0043071
up regulation of programmed cell death
up-regulation of programmed cell death
upregulation of programmed cell death
activation of programmed cell death
positive regulation of non-apoptotic programmed cell death
stimulation of programmed cell death
biological_process
positive regulation of programmed cell death
Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GOC:jl
Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GO:0043072
down regulation of programmed cell death
down-regulation of programmed cell death
downregulation of programmed cell death
inhibition of programmed cell death
negative regulation of non-apoptotic programmed cell death
biological_process
negative regulation of programmed cell death
Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
GOC:jl
Any process that activates or increases the activity of an enzyme.
GO:0048554
positive regulation of enzyme activity
up regulation of enzyme activity
up-regulation of enzyme activity
upregulation of enzyme activity
activation of enzyme activity
activation of metalloenzyme activity
positive regulation of metalloenzyme activity
stimulation of enzyme activity
stimulation of metalloenzyme activity
up regulation of metalloenzyme activity
up-regulation of metalloenzyme activity
upregulation of metalloenzyme activity
biological_process
positive regulation of catalytic activity
Any process that activates or increases the activity of an enzyme.
GOC:ebc
GOC:jl
GOC:tb
GOC:vw
positive regulation of enzyme activity
GOC:tb
Any process that stops or reduces the activity of an enzyme.
GO:0048553
down regulation of enzyme activity
down-regulation of enzyme activity
down-regulation of metalloenzyme activity
downregulation of enzyme activity
negative regulation of enzyme activity
down regulation of metalloenzyme activity
downregulation of metalloenzyme activity
inhibition of enzyme activity
inhibition of metalloenzyme activity
negative regulation of metalloenzyme activity
biological_process
negative regulation of catalytic activity
Any process that stops or reduces the activity of an enzyme.
GOC:ebc
GOC:jl
GOC:tb
GOC:vw
negative regulation of enzyme activity
GOC:tb
Any process that modulates the rate of GTP hydrolysis by a GTPase.
GO:0032312
GO:0032313
GO:0032314
GO:0032315
GO:0032316
GO:0032317
GO:0032318
GO:0032319
GO:0043088
regulation of ARF GTPase activity
regulation of Cdc42 GTPase activity
regulation of Rab GTPase activity
regulation of Rac GTPase activity
regulation of Ral GTPase activity
regulation of Ran GTPase activity
regulation of Rap GTPase activity
regulation of Ras GTPase activity
regulation of Rho GTPase activity
biological_process
regulation of GTPase activity
Any process that modulates the rate of GTP hydrolysis by a GTPase.
GOC:jl
GOC:mah
Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location.
establishment and maintenance of translational machinery localization
establishment and maintenance of translational protein localization
regulation of translation by machinery localisation
translational machinery localization
translational protein localization
biological_process
regulation of translation by machinery localization
Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location.
GOC:jl
regulation of translation by machinery localisation
GOC:mah
translational machinery localization
GOC:dph
GOC:tb
Interacting selectively and non-covalently with ions, charged atoms or groups of atoms.
molecular_function
atom binding
ion binding
Interacting selectively and non-covalently with ions, charged atoms or groups of atoms.
GOC:jl
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0043283
GO:0044259
biopolymer metabolic process
macromolecule metabolism
organismal macromolecule metabolism
multicellular organismal macromolecule metabolic process
biological_process
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:mah
biopolymer metabolic process
GOC:mtg_chebi_dec09
Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group.
molecular_function
amine binding
Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group.
GOC:jl
Interacting selectively and non-covalently with an organic acid, any acidic compound containing carbon in covalent linkage.
molecular_function
organic acid binding
Interacting selectively and non-covalently with an organic acid, any acidic compound containing carbon in covalent linkage.
GOC:jl
ISBN:0198506732
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane.
ATP-dependent carbohydrate transmembrane transporter activity
carbohydrate-transporting ATPase activity
carbohydrate ABC transporter
molecular_function
ATPase-coupled carbohydrate transmembrane transporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane.
GOC:mlg
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
NIF_Subcellular:sao1539965131
Wikipedia:Organelle
cellular_component
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GOC:go_curators
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
NIF_Subcellular:sao414196390
membrane-enclosed organelle
cellular_component
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GOC:go_curators
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
NIF_Subcellular:sao1456184038
non-membrane-enclosed organelle
cellular_component
non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GOC:go_curators
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
cellular_component
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GOC:go_curators
Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.
cellular_component
extracellular organelle
Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.
GOC:jl
PMID:9914479
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular membrane-enclosed organelle
cellular_component
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GOC:go_curators
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular non-membrane-enclosed organelle
cellular_component
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
GOC:go_curators
The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
cellular_component
organelle lumen
The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
GOC:jl
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
down regulation of protein complex disassembly
down-regulation of protein complex disassembly
downregulation of protein complex disassembly
inhibition of protein complex disassembly
biological_process
negative regulation of protein complex disassembly
negative regulation of protein-containing complex disassembly
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
GOC:jl
Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
up regulation of protein complex disassembly
up-regulation of protein complex disassembly
upregulation of protein complex disassembly
activation of protein complex disassembly
stimulation of protein complex disassembly
biological_process
positive regulation of protein complex disassembly
positive regulation of protein-containing complex disassembly
Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
GOC:jl
Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
biological_process
regulation of protein complex disassembly
regulation of protein-containing complex disassembly
Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
GOC:jl
The aggregation, arrangement and bonding together of a mature, active proteasome complex.
proteasome complex assembly
proteasome maturation
26S proteasome assembly
biological_process
proteasome assembly
The aggregation, arrangement and bonding together of a mature, active proteasome complex.
GOC:go_curators
PMID:10872471
Any process that modulates the frequency, rate or extent of protein complex assembly.
biological_process
regulation of protein complex assembly
regulation of protein-containing complex assembly
Any process that modulates the frequency, rate or extent of protein complex assembly.
GOC:jl
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates.
regulation of carbohydrate anabolism
regulation of carbohydrate biosynthesis
regulation of carbohydrate formation
regulation of carbohydrate synthesis
biological_process
regulation of carbohydrate biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates.
GOC:jl
Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
regulation of ion transport
Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:jl
Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of ion transport
up-regulation of ion transport
upregulation of ion transport
activation of ion transport
stimulation of ion transport
biological_process
positive regulation of ion transport
Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:jl
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of ion transport
down-regulation of ion transport
downregulation of ion transport
inhibition of ion transport
biological_process
negative regulation of ion transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:jl
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
up regulation of DNA binding
up-regulation of DNA binding
upregulation of DNA binding
activation of DNA binding
stimulation of DNA binding
biological_process
positive regulation of DNA binding
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GOC:dph
GOC:jl
GOC:tb
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
down regulation of DNA binding
down-regulation of DNA binding
downregulation of DNA binding
inhibition of DNA binding
biological_process
negative regulation of DNA binding
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GOC:dph
GOC:jl
GOC:tb
Any process that modulates the frequency, rate or extent of protein binding.
biological_process
regulation of protein binding
Any process that modulates the frequency, rate or extent of protein binding.
GOC:go_curators
The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
biological_process
macromolecule modification
The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
2011-07-15T10:56:12Z
GO:1904168
GO:2000824
negative regulation of transcription factor activity
down regulation of transcription factor activity
down-regulation of transcription factor activity
downregulation of transcription factor activity
negative regulation of DNA binding transcription factor activity
negative regulation of sequence-specific DNA binding transcription factor activity
inhibition of transcription factor activity
negative regulation of androgen receptor activity
negative regulation of thyroid hormone receptor activity
biological_process
negative regulation of DNA-binding transcription factor activity
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
GOC:jl
negative regulation of transcription factor activity
GOC:dph
GOC:tb
The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
keto acid metabolic process
keto acid metabolism
ketoacid metabolic process
ketoacid metabolism
oxo acid metabolic process
oxo acid metabolism
oxoacid metabolism
biological_process
oxoacid metabolic process
The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
Wikipedia:Oxyacid
Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
regulation of secondary metabolism
biological_process
regulation of secondary metabolic process
Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
GOC:jl
Any process that modulates the rate of ATP hydrolysis by an ATPase.
regulation of adenosinetriphosphatase activity
biological_process
regulation of ATPase activity
Any process that modulates the rate of ATP hydrolysis by an ATPase.
GOC:jl
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.
biological_process
regulation of generation of precursor metabolites and energy
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.
GOC:jl
Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.
biological_process
regulation of carbohydrate catabolic process
Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.
GOC:mlg
The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
biological_process
pigmentation
The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
GOC:jl
Any process that activates or increases the activity of a GTPase.
GO:0032320
GO:0032321
GO:0032850
GO:0032851
GO:0032852
GO:0032853
GO:0032854
GO:0032855
GO:0043089
up regulation of GTPase activity
up-regulation of GTPase activity
upregulation of GTPase activity
activation of GTPase activity
positive regulation of ARF GTPase activity
positive regulation of Cdc42 GTPase activity
positive regulation of Rab GTPase activity
positive regulation of Rac GTPase activity
positive regulation of Ral GTPase activity
positive regulation of Ran GTPase activity
positive regulation of Rap GTPase activity
positive regulation of Ras GTPase activity
positive regulation of Rho GTPase activity
stimulation of ARF GTPase activity
stimulation of Cdc42 GTPase activity
stimulation of GTPase activity
stimulation of Rab GTPase activity
stimulation of Rac GTPase activity
stimulation of Ral GTPase activity
stimulation of Ran GTPase activity
stimulation of Rap GTPase activity
stimulation of Ras GTPase activity
stimulation of Rho GTPase activity
up regulation of ARF GTPase activity
up regulation of Cdc42 GTPase activity
up regulation of Rab GTPase activity
up regulation of Rac GTPase activity
up regulation of Ral GTPase activity
up regulation of Ran GTPase activity
up regulation of Rap GTPase activity
up regulation of Ras GTPase activity
up regulation of Rho GTPase activity
up-regulation of ARF GTPase activity
up-regulation of Cdc42 GTPase activity
up-regulation of Rab GTPase activity
up-regulation of Rac GTPase activity
up-regulation of Ral GTPase activity
up-regulation of Ran GTPase activity
up-regulation of Rap GTPase activity
up-regulation of Ras GTPase activity
up-regulation of Rho GTPase activity
upregulation of ARF GTPase activity
upregulation of Cdc42 GTPase activity
upregulation of Rab GTPase activity
upregulation of Rac GTPase activity
upregulation of Ral GTPase activity
upregulation of Ran GTPase activity
upregulation of Rap GTPase activity
upregulation of Ras GTPase activity
upregulation of Rho GTPase activity
biological_process
positive regulation of GTPase activity
Any process that activates or increases the activity of a GTPase.
GOC:jl
GOC:mah
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
biological_process
regulation of kinase activity
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GOC:bf
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
sequence specific DNA binding
molecular_function
sequence-specific DNA binding
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
GOC:jl
The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA.
biological_process
plastid fission
The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA.
GOC:jl
Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
biological_process
peroxisomal transport
Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
GOC:jl
The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.
biological_process
cellular protein complex disassembly
The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.
GOC:jl
Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
biological_process
regulation of multi-organism process
Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
GOC:jl
Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
biological_process
negative regulation of multi-organism process
Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
GOC:jl
Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
biological_process
positive regulation of multi-organism process
Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
GOC:jl
Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.
https://github.com/geneontology/go-ontology/issues/19222
biological_process
regulation of symbiosis, encompassing mutualism through parasitism
regulation of interspecies interactions between organisms
Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.
GOC:jl
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.
midori
2010-09-08T10:01:42Z
GO:0034600
GO:0034621
GO:0071822
protein complex subunit organisation
protein complex subunit organization
biological_process
cellular macromolecular complex organization
cellular macromolecular complex subunit organisation
cellular macromolecular complex subunit organization
macromolecular complex organization
macromolecular complex subunit organisation
macromolecular complex subunit organization
protein-containing complex subunit organization
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.
GOC:mah
protein complex subunit organisation
GOC:mah
A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves more than one organism.
multi-organism metabolism
multi-organismal metabolic process
multi-organismal metabolism
biological_process
multi-organism metabolic process
A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves more than one organism.
GOC:jl
A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves more than one organism.
multi-organism catabolism
multi-organismal catabolic process
multi-organismal catabolism
biological_process
multi-organism catabolic process
A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves more than one organism.
GOC:jl
The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GO:0010382
cellular cell wall macromolecule metabolic process
cellular cell wall macromolecule metabolism
biological_process
cell wall macromolecule metabolic process
The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GOC:jl
GOC:mah
The chemical reactions and pathways involving macromolecules forming, or destined to form, part of a cell wall, involving more than one organism. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
multi-organism cell wall macromolecule metabolism
biological_process
multi-organism cell wall macromolecule metabolic process
The chemical reactions and pathways involving macromolecules forming, or destined to form, part of a cell wall, involving more than one organism. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GOC:mah
GOC:tair_curators
multi-organism cell wall macromolecule metabolism
GOC:mah
The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall.
cell wall macromolecule anabolism
cell wall macromolecule biosynthesis
cell wall macromolecule biosynthetic process at cellular level
cell wall macromolecule synthesis
cellular cell wall macromolecule biosynthetic process
biological_process
cell wall macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall.
GOC:go_curators
cell wall macromolecule anabolism
GOC:mah
cell wall macromolecule biosynthesis
GOC:mah
cell wall macromolecule biosynthetic process at cellular level
GOC:mah
cell wall macromolecule synthesis
GOC:mah
cellular cell wall macromolecule biosynthetic process
GOC:mah
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, that involve more than one organism.
multi-organism carbohydrate metabolism
main pathways of carbohydrate metabolic process
main pathways of carbohydrate metabolism
biological_process
multi-organism carbohydrate metabolic process
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, that involve more than one organism.
GOC:jl
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, involving more than one organism.
multi-organism carbohydrate breakdown
multi-organism carbohydrate catabolism
multi-organism carbohydrate degradation
biological_process
multi-organism carbohydrate catabolic process
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, involving more than one organism.
GOC:jl
Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.
biological_process
regulation of system process
Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.
GOC:jl
A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.
GO:0071843
cellular component biogenesis at cellular level
biological_process
cellular component biogenesis
A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.
GOC:jl
GOC:mah
Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
biological_process
regulation of cellular component biogenesis
Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
GOC:jl
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
regulation of vacuole organisation
biological_process
regulation of vacuole biogenesis
regulation of vacuole organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
GOC:jl
GOC:mah
regulation of vacuole organisation
GOC:mah
regulation of vacuole biogenesis
GOC:mah
Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
biological_process
positive regulation of cellular component biogenesis
Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
GOC:jl
Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
positive regulation of vacuole organisation
biological_process
positive regulation of vacuole biogenesis
positive regulation of vacuole organization
Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
GOC:jl
GOC:mah
positive regulation of vacuole organisation
GOC:mah
positive regulation of vacuole biogenesis
GOC:mah
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.
biological_process
membrane biogenesis
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.
GOC:jl
Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
jane
2009-04-21T04:07:27Z
biological_process
negative regulation of molecular function
Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:jl
Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
jane
2009-04-21T04:11:06Z
biological_process
positive regulation of molecular function
Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:jl
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
jane
2009-07-15T11:55:44Z
biological_process
cellular amine metabolic process
The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
GOC:jl
The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.
jane
2009-07-30T02:26:46Z
GO:0044152
development on or near surface of other organism involved in symbiotic interaction
biological_process
development during symbiotic interaction
development on or near surface of other organism during symbiotic interaction
This term partially replaces the obsolete term 'growth or development during symbiotic interaction ; GO:0052171'. See also 'growth during symbiotic interaction ; GO:0044110'.
development involved in symbiotic interaction
The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.
GO:jl
GOC:pamgo_curators
development during symbiotic interaction
gOC:dph
development on or near surface of other organism during symbiotic interaction
GOC:dph
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.
jane
2009-09-25T11:33:48Z
chaperone activity
protein binding involved in protein folding
molecular_function
protein folding chaperone
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.
GOC:mtg_cambridge_2009
A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
jane
2009-10-22T02:38:55Z
translation initiation (ternary) complex
Met-tRNA/eIF2.GTP ternary complex
cellular_component
translation initiation ternary complex
A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
GOC:jl
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
kchris
2009-11-04T12:58:25Z
GO:0000975
regulatory region DNA binding
molecular_function
To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind, and "enhancer" regions which are typically more distal from the core promoter. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription. ANNOTATION NOTE: Regarding annotation to "transcription regulatory region DNA binding" (GO:0044212) and any of its is_a children, note that annotation to these terms specifies DNA binding only without any statement about transcription factor activity. To make an annotation about a function of transcription factor activity, consider "sequence-specific DNA-binding transcription factor activity" (GO:0003700) or its is_a children which have has_part relationships to the appropriate kind of "transcription regulatory region DNA binding".
transcription regulatory region DNA binding
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
GOC:jl
GOC:txnOH
SO:0005836
The chemical reactions and pathways by which individual cells transform chemical substances.
cellular metabolism
biological_process
intermediary metabolism
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
GOC:go_curators
intermediary metabolism
GOC:mah
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
primary metabolism
biological_process
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GOC:go_curators
http://www.metacyc.org
The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.
cellular lipid breakdown
cellular lipid catabolism
cellular lipid degradation
biological_process
cellular lipid catabolic process
The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.
GOC:jl
The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
cellular breakdown
cellular catabolism
cellular degradation
biological_process
cellular catabolic process
The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GOC:jl
The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
cellular anabolism
cellular biosynthesis
cellular formation
cellular synthesis
biological_process
cellular biosynthetic process
The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GOC:jl
The chemical reactions and pathways involving lipids, as carried out by individual cells.
cellular lipid metabolism
biological_process
cellular lipid metabolic process
The chemical reactions and pathways involving lipids, as carried out by individual cells.
GOC:jl
The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
cellular protein breakdown
cellular protein catabolism
cellular protein degradation
biological_process
cellular protein catabolic process
The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
GOC:jl
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0034960
cellular biopolymer metabolic process
cellular macromolecule metabolism
biological_process
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GOC:mah
cellular biopolymer metabolic process
GOC:mtg_chebi_dec09
The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells.
GO:0034962
cellular biopolymer catabolic process
cellular macromolecule breakdown
cellular macromolecule catabolism
cellular macromolecule degradation
biological_process
cellular macromolecule catabolic process
The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells.
GOC:jl
cellular biopolymer catabolic process
GOC:mtg_chebi_dec09
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
cellular protein metabolism
biological_process
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
GOC:jl
The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.
nitrogen compound breakdown
nitrogen compound catabolism
nitrogen compound degradation
biological_process
cellular nitrogen compound catabolic process
The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.
GOC:jl
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
nitrogen compound anabolism
nitrogen compound biosynthesis
nitrogen compound formation
nitrogen compound synthesis
biological_process
cellular nitrogen compound biosynthetic process
The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
GOC:jl
ISBN:0198506732
The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
sulfur compound anabolism
sulfur compound biosynthesis
sulfur compound formation
sulfur compound synthesis
sulfur biosynthesis
sulfur biosynthetic process
biological_process
sulfur compound biosynthetic process
The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GOC:jl
The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
sulfur compound breakdown
sulfur compound catabolism
sulfur compound degradation
sulfur catabolic process
sulfur catabolism
biological_process
sulfur compound catabolic process
The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GOC:jl
A process that results in the breakdown of the cell wall.
jane
2010-01-14T02:00:34Z
GO:0060871
cellular cell wall disassembly
biological_process
cell wall disassembly
A process that results in the breakdown of the cell wall.
GOC:jl
The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
jane
2010-01-26T12:05:20Z
small molecule metabolism
biological_process
Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
small molecule metabolic process
The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
GOC:curators
GOC:pde
GOC:vw
The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.
jane
2010-01-26T12:06:10Z
small molecule catabolism
biological_process
Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
small molecule catabolic process
The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.
GOC:curators
GOC:vw
The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.
jane
2010-01-26T12:06:49Z
small molecule biosynthesis
biological_process
Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
small molecule biosynthetic process
The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.
GOC:curators
GOC:pde
GOC:vw
A process in which a protein is transported to, or maintained in, a location within the cytoskeleton.
janelomax
2011-12-13T11:43:24Z
protein localisation to cytoskeleton
biological_process
protein localization to cytoskeleton
A process in which a protein is transported to, or maintained in, a location within the cytoskeleton.
GOC:jl
protein localisation to cytoskeleton
GOC:mah
A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts.
https://github.com/geneontology/go-ontology/issues/14807
GO:0043298
GO:0044404
GO:0072519
GO:0085031
commensalism
host-pathogen interaction
parasitism
biological_process
symbiosis
symbiosis, encompassing mutualism through parasitism
symbiotic interaction
symbiotic interaction between host and organism
symbiotic interaction between organisms
symbiotic interaction between species
symbiotic process
A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts.
GOC:cc
https://study.com/academy/lesson/symbiont-definition-lesson-quiz.html
Any process in which an organism has an effect on an organism of a different species.
interaction with another species
interspecies interaction
interspecies interaction with other organisms
biological_process
interspecies interaction between organisms
Any process in which an organism has an effect on an organism of a different species.
GOC:cc
A biological process that directly contributes to the process of producing new individuals, involving another organism.
janelomax
2012-09-19T15:56:30Z
biological_process
multi-organism reproductive process
A biological process that directly contributes to the process of producing new individuals, involving another organism.
GOC:jl
A multicellular organism process which involves another multicellular organism of the same or different species.
janelomax
2012-09-19T16:06:16Z
biological_process
multi-multicellular organism process
A multicellular organism process which involves another multicellular organism of the same or different species.
GOC:jl
Any process that is carried out at the cellular level which involves another organism of the same or different species.
janelomax
2012-12-11T17:00:50Z
biological_process
multi-organism cellular process
Any process that is carried out at the cellular level which involves another organism of the same or different species.
GOC:jl
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism.
janelomax
2012-12-13T16:25:50Z
biological_process
multi-organism transport
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism.
GOC:jl
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
janelomax
2013-03-27T15:09:58Z
microtubule-based flagellum organization
biological_process
Note that we deem cilium and microtubule-based flagellum to be equivalent.
cilium organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GOC:cilia
GOC:jl
The membrane organization process that joins two lipid bilayers to form a single membrane, involving more than one organism.
janelomax
2013-09-10T15:06:11Z
biological_process
multi-organism membrane fusion
The membrane organization process that joins two lipid bilayers to form a single membrane, involving more than one organism.
GOC:jl
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving more than one organism.
janelomax
2013-09-10T15:11:41Z
biological_process
multi-organism membrane organization
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving more than one organism.
GOC:jl
A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded.
janelomax
2013-09-10T15:50:25Z
nucleus degradation
biological_process
nucleophagy
autophagy of nucleus
A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded.
GOC:autophagy
GOC:jl
PMID:24013549
Interacting selectively and non-covalently with a macromolecular complex.
janelomax
2014-12-16T11:38:58Z
GO:0032403
protein complex binding
molecular_function
macromolecular complex binding
protein-containing complex binding
Interacting selectively and non-covalently with a macromolecular complex.
GOC:jl
The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell.
GO:0006947
cell fusion
cell-cell fusion
biological_process
plasma membrane fusion
The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell.
GOC:elh
GOC:mtg_muscle
The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p.
biological_process
Note that 'vectorial' is used in the definition in the mathematical and physical sense of pertaining to 'a quantity having direction as well as magnitude, especially as determining the position of one point in space relative to another.
peroxisome inheritance
The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p.
PMID:11733545
The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
protein targeting to endoplasmic reticulum
protein-ER targeting
protein-endoplasmic reticulum targeting
biological_process
protein targeting to ER
The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
ISBN:0716731363
Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
translation factor activity
molecular_function
translation regulator activity
Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
GOC:ai
The directed movement of a protein to a specific location.
establishment of protein localisation
protein positioning
protein recruitment
biological_process
establishment of protein localization
The directed movement of a protein to a specific location.
GOC:bf
establishment of protein localisation
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell.
external encapsulating structure organisation
external encapsulating structure organization and biogenesis
biological_process
external encapsulating structure organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell.
GOC:ai
GOC:dph
GOC:jl
GOC:mah
external encapsulating structure organization and biogenesis
GOC:dph
GOC:jl
GOC:mah
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
biological_process
regulation of cell differentiation
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
down regulation of cell differentiation
down-regulation of cell differentiation
downregulation of cell differentiation
inhibition of cell differentiation
biological_process
negative regulation of cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of cell differentiation.
up regulation of cell differentiation
up-regulation of cell differentiation
upregulation of cell differentiation
activation of cell differentiation
stimulation of cell differentiation
biological_process
positive regulation of cell differentiation
Any process that activates or increases the frequency, rate or extent of cell differentiation.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the formation of a cilium.
positive regulation of flagellum assembly
up regulation of cilium assembly
up-regulation of cilium assembly
upregulation of cilium assembly
activation of cilium assembly
stimulation of cilium assembly
biological_process
positive regulation of flagellum biogenesis
positive regulation of cilium assembly
Any process that activates or increases the frequency, rate or extent of the formation of a cilium.
GOC:cilia
GOC:go_curators
positive regulation of flagellum biogenesis
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
GO:0045946
positive regulation of protein anabolism
positive regulation of protein biosynthesis
positive regulation of protein biosynthetic process
positive regulation of protein formation
positive regulation of protein synthesis
up regulation of protein biosynthetic process
up-regulation of protein biosynthetic process
upregulation of protein biosynthetic process
activation of protein biosynthetic process
stimulation of protein biosynthetic process
biological_process
positive regulation of translation
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
GOC:dph
GOC:go_curators
GOC:tb
positive regulation of protein biosynthetic process
GOC:tb
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
positive regulation of protein breakdown
positive regulation of protein catabolism
positive regulation of protein degradation
up regulation of protein catabolic process
up-regulation of protein catabolic process
upregulation of protein catabolic process
activation of protein catabolic process
stimulation of protein catabolic process
biological_process
positive regulation of protein catabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid.
down regulation of amino acid metabolic process
down-regulation of amino acid metabolic process
downregulation of amino acid metabolic process
negative regulation of amino acid metabolism
inhibition of amino acid metabolic process
biological_process
negative regulation of cellular amino acid metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid.
positive regulation of amino acid metabolism
up regulation of amino acid metabolic process
up-regulation of amino acid metabolic process
upregulation of amino acid metabolic process
activation of amino acid metabolic process
stimulation of amino acid metabolic process
biological_process
positive regulation of cellular amino acid metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of cell adhesion.
up regulation of cell adhesion
up-regulation of cell adhesion
upregulation of cell adhesion
activation of cell adhesion
stimulation of cell adhesion
biological_process
positive regulation of cell adhesion
Any process that activates or increases the frequency, rate or extent of cell adhesion.
GOC:go_curators
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
down regulation of progression through cell cycle
down-regulation of progression through cell cycle
downregulation of progression through cell cycle
negative regulation of cell cycle progression
negative regulation of progression through cell cycle
inhibition of progression through cell cycle
biological_process
negative regulation of cell cycle
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
GOC:dph
GOC:go_curators
GOC:tb
Any process that activates or increases the rate or extent of progression through the cell cycle.
positive regulation of cell cycle progression
positive regulation of progression through cell cycle
up regulation of progression through cell cycle
up-regulation of progression through cell cycle
upregulation of progression through cell cycle
activation of progression through cell cycle
stimulation of progression through cell cycle
biological_process
positive regulation of cell cycle
Any process that activates or increases the rate or extent of progression through the cell cycle.
GOC:go_curators
positive regulation of progression through cell cycle
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
down regulation of lipid metabolic process
down-regulation of lipid metabolic process
downregulation of lipid metabolic process
negative regulation of lipid metabolism
inhibition of lipid metabolic process
biological_process
negative regulation of lipid metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
positive regulation of lipid metabolism
up regulation of lipid metabolic process
up-regulation of lipid metabolic process
upregulation of lipid metabolic process
activation of lipid metabolic process
stimulation of lipid metabolic process
biological_process
positive regulation of lipid metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
GOC:go_curators
Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
down regulation of mitosis
down-regulation of mitosis
downregulation of mitosis
negative regulation of mitosis
inhibition of mitosis
biological_process
negative regulation of mitotic nuclear division
Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
GOC:dph
GOC:go_curators
GOC:tb
Any process that activates or increases the frequency, rate or extent of mitosis.
positive regulation of mitosis
up regulation of mitosis
up-regulation of mitosis
upregulation of mitosis
activation of mitosis
mitogenic activity
stimulation of mitosis
biological_process
positive regulation of mitotic nuclear division
Any process that activates or increases the frequency, rate or extent of mitosis.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
down regulation of proteolysis
down-regulation of proteolysis
downregulation of proteolysis
negative regulation of peptidolysis
inhibition of proteolysis
biological_process
negative regulation of proteolysis
Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
positive regulation of peptidolysis
up regulation of proteolysis
up-regulation of proteolysis
upregulation of proteolysis
activation of proteolysis
stimulation of proteolysis
biological_process
positive regulation of proteolysis
Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
GO:0016481
GO:0032582
GO:0061021
down regulation of transcription, DNA-dependent
down-regulation of transcription, DNA-dependent
downregulation of transcription, DNA-dependent
negative regulation of cellular transcription, DNA-dependent
negative regulation of transcription, DNA-dependent
inhibition of transcription, DNA-dependent
biological_process
down regulation of gene-specific transcription
down-regulation of gene-specific transcription
downregulation of gene-specific transcription
inhibition of gene-specific transcription
negative regulation of gene-specific transcription
transcription repressor activity
negative regulation of transcription, DNA-templated
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
GOC:go_curators
GOC:txnOH
negative regulation of transcription, DNA-dependent
GOC:txnOH
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
GO:0043193
GO:0045941
GO:0061020
positive regulation of cellular transcription, DNA-dependent
positive regulation of transcription, DNA-dependent
up regulation of transcription, DNA-dependent
up-regulation of transcription, DNA-dependent
upregulation of transcription, DNA-dependent
activation of transcription, DNA-dependent
stimulation of gene-specific transcription
stimulation of transcription, DNA-dependent
biological_process
activation of gene-specific transcription
positive regulation of gene-specific transcription
transcription activator activity
up regulation of gene-specific transcription
up-regulation of gene-specific transcription
upregulation of gene-specific transcription
positive regulation of transcription, DNA-templated
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
GOC:go_curators
GOC:txnOH
positive regulation of transcription, DNA-dependent
GOC:txnOH
Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation.
down regulation of translational elongation
down-regulation of translational elongation
downregulation of translational elongation
inhibition of translational elongation
biological_process
negative regulation of translational elongation
Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of translational elongation.
up regulation of translational elongation
up-regulation of translational elongation
upregulation of translational elongation
activation of translational elongation
stimulation of translational elongation
biological_process
positive regulation of translational elongation
Any process that activates or increases the frequency, rate or extent of translational elongation.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination.
down regulation of translational termination
down-regulation of translational termination
downregulation of translational termination
inhibition of translational termination
biological_process
negative regulation of translational termination
Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of translational termination.
up regulation of translational termination
up-regulation of translational termination
upregulation of translational termination
activation of translational termination
stimulation of translational termination
biological_process
positive regulation of translational termination
Any process that activates or increases the frequency, rate or extent of translational termination.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
down regulation of carbohydrate metabolic process
down-regulation of carbohydrate metabolic process
downregulation of carbohydrate metabolic process
negative regulation of carbohydrate metabolism
inhibition of carbohydrate metabolic process
biological_process
negative regulation of carbohydrate metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
positive regulation of carbohydrate metabolism
up regulation of carbohydrate metabolic process
up-regulation of carbohydrate metabolic process
upregulation of carbohydrate metabolic process
activation of carbohydrate metabolic process
stimulation of carbohydrate metabolic process
biological_process
positive regulation of carbohydrate metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.
down regulation of exocytosis
down-regulation of exocytosis
downregulation of exocytosis
inhibition of exocytosis
biological_process
negative regulation of exocytosis
Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of exocytosis.
up regulation of exocytosis
up-regulation of exocytosis
upregulation of exocytosis
activation of exocytosis
stimulation of exocytosis
biological_process
positive regulation of exocytosis
Any process that activates or increases the frequency, rate or extent of exocytosis.
GOC:go_curators
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
down regulation of growth
down-regulation of growth
downregulation of growth
inhibition of growth
biological_process
negative regulation of growth
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
GOC:go_curators
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
up regulation of growth
up-regulation of growth
upregulation of growth
activation of growth
stimulation of growth
biological_process
positive regulation of growth
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
GOC:go_curators
Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.
down regulation of progression through mitotic cell cycle
down-regulation of progression through mitotic cell cycle
downregulation of progression through mitotic cell cycle
negative regulation of mitotic cell cycle progression
negative regulation of progression through mitotic cell cycle
inhibition of progression through mitotic cell cycle
biological_process
negative regulation of mitotic cell cycle
Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.
GOC:dph
GOC:go_curators
GOC:tb
negative regulation of progression through mitotic cell cycle
GOC:dph
GOC:tb
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
positive regulation of mitotic cell cycle progression
positive regulation of progression through mitotic cell cycle
up regulation of progression through mitotic cell cycle
up-regulation of progression through mitotic cell cycle
upregulation of progression through mitotic cell cycle
activation of progression through mitotic cell cycle
stimulation of progression through mitotic cell cycle
biological_process
positive regulation of mitotic cell cycle
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
GOC:dph
GOC:go_curators
GOC:tb
positive regulation of progression through mitotic cell cycle
GOC:dph
GOC:tb
Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
biological_process
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
negative regulation of nucleobase-containing compound metabolic process
Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:go_curators
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GOC:dph
GOC:tb
Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
biological_process
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
positive regulation of nucleobase-containing compound metabolic process
Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
GOC:go_curators
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GOC:dph
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
down regulation of phosphate metabolic process
down-regulation of phosphate metabolic process
downregulation of phosphate metabolic process
negative regulation of phosphate metabolism
inhibition of phosphate metabolic process
biological_process
negative regulation of phosphate metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
positive regulation of phosphate metabolism
up regulation of phosphate metabolic process
up-regulation of phosphate metabolic process
upregulation of phosphate metabolic process
activation of phosphate metabolic process
stimulation of phosphate metabolic process
biological_process
positive regulation of phosphate metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GOC:go_curators
Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.
down regulation of translational initiation
down-regulation of translational initiation
downregulation of translational initiation
inhibition of translational initiation
biological_process
negative regulation of translational initiation
Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.
GOC:go_curators
Any process that activates or increases the frequency, rate or extent of translational initiation.
up regulation of translational initiation
up-regulation of translational initiation
upregulation of translational initiation
activation of translational initiation
stimulation of translational initiation
biological_process
positive regulation of translational initiation
Any process that activates or increases the frequency, rate or extent of translational initiation.
GOC:go_curators
Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein.
biological_process
regulation of translation, ncRNA-mediated
Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein.
GOC:dph
GOC:go_curators
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.
down regulation of embryonic development
down-regulation of embryonic development
downregulation of embryonic development
inhibition of embryonic development
biological_process
negative regulation of embryonic development
Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.
GOC:go_curators
Any process that modulates the frequency, rate or extent of embryonic development.
biological_process
regulation of embryonic development
Any process that modulates the frequency, rate or extent of embryonic development.
GOC:go_curators
The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
carboxylic acid anabolism
carboxylic acid biosynthesis
carboxylic acid formation
carboxylic acid synthesis
biological_process
carboxylic acid biosynthetic process
The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
ISBN:0198506732
The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
carboxylic acid breakdown
carboxylic acid catabolism
carboxylic acid degradation
biological_process
carboxylic acid catabolic process
The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
ISBN:0198506732
The addition of tubulin heterodimers to one or both ends of a microtubule.
microtubule assembly
biological_process
microtubule formation
microtubule polymerization
The addition of tubulin heterodimers to one or both ends of a microtubule.
GOC:ai
GOC:go_curators
Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
biological_process
regulation of nucleocytoplasmic transport
Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
GOC:bf
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.
down regulation of nucleocytoplasmic transport
down-regulation of nucleocytoplasmic transport
downregulation of nucleocytoplasmic transport
inhibition of nucleocytoplasmic transport
biological_process
negative regulation of nucleocytoplasmic transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.
GOC:bf
Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
up regulation of nucleocytoplasmic transport
up-regulation of nucleocytoplasmic transport
upregulation of nucleocytoplasmic transport
activation of nucleocytoplasmic transport
stimulation of nucleocytoplasmic transport
biological_process
positive regulation of nucleocytoplasmic transport
Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
GOC:bf
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
positive regulation of lipid anabolism
positive regulation of lipid biosynthesis
positive regulation of lipid formation
positive regulation of lipid synthesis
positive regulation of lipogenesis
up regulation of lipid biosynthetic process
up-regulation of lipid biosynthetic process
upregulation of lipid biosynthetic process
activation of lipid biosynthetic process
stimulation of lipid biosynthetic process
biological_process
positive regulation of lipid biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
GOC:ai
positive regulation of lipogenesis
GOC:sl
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
regulation of lipid anabolism
regulation of lipid biosynthesis
regulation of lipid formation
regulation of lipid synthesis
regulation of lipogenesis
biological_process
regulation of lipid biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
GOC:ai
regulation of lipogenesis
GOC:sl
The controlled release of a substance by a cell or a tissue.
biological_process
secretion
The controlled release of a substance by a cell or a tissue.
GOC:ai
The directed movement of substances within a cell.
jl
2013-12-18T14:04:50Z
GO:1902582
biological_process
single organism intracellular transport
single-organism intracellular transport
intracellular transport
The directed movement of substances within a cell.
GOC:ai
single organism intracellular transport
GOC:TermGenie
The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
biological_process
carboxylic acid transport
The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
GOC:ai
The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell.
cytosol to ER transport
cytosol to endoplasmic reticulum transport
biological_process
cytosol to endoplasmic reticulum transport
The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell.
GOC:ai
The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
microtubule-based vesicle localization
biological_process
vesicle transport along microtubule
The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
GOC:ecd
GOC:rl
microtubule-based vesicle localization
GOC:rl
The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
mitochondrial migration along microtubule
mitochondrial transport along microtubule
biological_process
mitochondrion transport along microtubule
The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
GOC:ecd
Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
molecular_function
cofactor binding
Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
ISBN:0198506732
The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
biological_process
Golgi-derived vesicle transport
Golgi vesicle transport
The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
GOC:jid
ISBN:0716731363
PMID:10219233
The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.
Golgi vesicle targeting
dictyosome vesicle targeting
vesicle targeting, to, from or within dictyosome
biological_process
vesicle targeting, to, from or within Golgi
The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.
GOC:jid
GOC:mah
ISBN:0716731363
PMID:10219233
Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.
regulation of Golgi vesicle targeting
biological_process
regulation of vesicle targeting, to, from or within Golgi
Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.
GOC:jid
GOC:mah
ISBN:0716731363
PMID:10219233
Transport of a vesicle from the plasma membrane to the endosome.
biological_process
plasma membrane to endosome transport
Transport of a vesicle from the plasma membrane to the endosome.
GOC:jid
The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum.
vesicle fusion with ER
biological_process
vesicle fusion with endoplasmic reticulum
The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum.
GOC:jid
The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.
biological_process
vesicle fusion with Golgi apparatus
The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.
GOC:jid
The creation of a single organelle from two or more organelles.
biological_process
organelle fusion
The creation of a single organelle from two or more organelles.
GOC:jid
The creation of two or more organelles by division of one organelle.
biological_process
organelle fission
The creation of two or more organelles by division of one organelle.
GOC:jid
The partitioning of organelles between daughter cells at cell division.
biological_process
organelle inheritance
The partitioning of organelles between daughter cells at cell division.
GOC:jid
The partitioning of endoplasmic reticulum between daughter cells at cell division.
ER inheritance
biological_process
endoplasmic reticulum inheritance
The partitioning of endoplasmic reticulum between daughter cells at cell division.
GOC:jid
The partitioning of nuclei between daughter cells at cell division.
cell nucleus inheritance
biological_process
nucleus inheritance
The partitioning of nuclei between daughter cells at cell division.
GOC:jid
Any process that establishes the spatial arrangement of mitochondria between and within cells.
distribution of mitochondria
mitochondrial distribution
biological_process
positioning of mitochondria
mitochondrion distribution
Any process that establishes the spatial arrangement of mitochondria between and within cells.
GOC:jid
The partitioning of Golgi apparatus between daughter cells at cell division.
Golgi division
Golgi partitioning
biological_process
Golgi inheritance
The partitioning of Golgi apparatus between daughter cells at cell division.
GOC:jid
PMID:12851069
Golgi division
GOC:ascb_2009
GOC:dph
GOC:tb
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
biological_process
terminal differentiation
cell development
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GOC:go_curators
terminal differentiation
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0043119
positive regulation of physiological process
up regulation of biological process
up-regulation of biological process
upregulation of biological process
activation of biological process
stimulation of biological process
biological_process
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GOC:jid
Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0043118
down regulation of biological process
down-regulation of biological process
downregulation of biological process
negative regulation of physiological process
inhibition of biological process
biological_process
negative regulation of biological process
Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GOC:jid
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051242
positive regulation of cellular physiological process
up regulation of cellular process
up-regulation of cellular process
upregulation of cellular process
activation of cellular process
stimulation of cellular process
biological_process
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GOC:jid
Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051243
down regulation of cellular process
down-regulation of cellular process
downregulation of cellular process
negative regulation of cellular physiological process
inhibition of cellular process
biological_process
negative regulation of cellular process
Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GOC:jid
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
biological_process
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GOC:jid
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
up regulation of response to stimulus
up-regulation of response to stimulus
upregulation of response to stimulus
activation of response to stimulus
stimulation of response to stimulus
biological_process
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GOC:jid
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
down regulation of response to stimulus
down-regulation of response to stimulus
downregulation of response to stimulus
inhibition of response to stimulus
biological_process
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
negative regulation of response to stimulus
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GOC:jid
The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
formation of an anatomical structure involved in morphogenesis
biological_process
Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense.
anatomical structure formation involved in morphogenesis
The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GOC:dph
GOC:jid
GOC:tb
formation of an anatomical structure involved in morphogenesis
GOC:dph
GOC:tb
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
biological_process
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GOC:dph
GOC:jid
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
development of an anatomical structure
biological_process
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO_REF:0000021
The process in which the anatomical structures of a cell projection are generated and organized.
biological_process
cell projection morphogenesis
The process in which the anatomical structures of a cell projection are generated and organized.
GO_REF:0000021
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
biological_process
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
GOC:isa_complete
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
cell locomotion
movement of a cell
biological_process
cell movement
cell motility
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
GOC:dgh
GOC:dph
GOC:isa_complete
GOC:mlg
Any process in which a chromosome is transported to, or maintained in, a specific location.
chromosome localisation
establishment and maintenance of chromosome localization
establishment and maintenance of chromosome position
biological_process
chromosome localization
Any process in which a chromosome is transported to, or maintained in, a specific location.
GOC:ai
chromosome localisation
GOC:mah
The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
nucleic acid transport
The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
ISBN:0198506732
The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
RNA transport
The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.
biological_process
regulation of mRNA processing
Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.
GOC:ai
Any process that activates or increases the frequency, rate or extent of mRNA processing.
up regulation of mRNA processing
up-regulation of mRNA processing
upregulation of mRNA processing
activation of mRNA processing
stimulation of mRNA processing
biological_process
positive regulation of mRNA processing
Any process that activates or increases the frequency, rate or extent of mRNA processing.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.
down regulation of mRNA processing
down-regulation of mRNA processing
downregulation of mRNA processing
inhibition of mRNA processing
biological_process
negative regulation of mRNA processing
Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.
GOC:ai
Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
biological_process
regulation of protein secretion
Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
down regulation of protein secretion
down-regulation of protein secretion
downregulation of protein secretion
inhibition of protein secretion
biological_process
negative regulation of protein secretion
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
up regulation of protein secretion
up-regulation of protein secretion
upregulation of protein secretion
activation of protein secretion
stimulation of protein secretion
biological_process
positive regulation of protein secretion
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
GOC:ai
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0050791
regulation of physiological process
biological_process
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GOC:ai
GOC:go_curators
Any process that modulates the activity of an enzyme.
GO:0048552
regulation of enzyme activity
regulation of metalloenzyme activity
biological_process
regulation of catalytic activity
Any process that modulates the activity of an enzyme.
GOC:ai
GOC:ebc
GOC:vw
Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
biological_process
regulation of developmental process
Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GOC:go_curators
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051244
regulation of cellular physiological process
biological_process
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GOC:go_curators
Interacting selectively and non-covalently with a component of the extracellular matrix.
extracellular matrix constituent binding
molecular_function
adhesive extracellular matrix constituent
extracellular matrix binding
Interacting selectively and non-covalently with a component of the extracellular matrix.
GOC:ai
A organ system process carried out by any of the organs or tissues of neurological system.
https://github.com/geneontology/go-ontology/issues/13824
neurological system process
neurophysiological process
biological_process
pan-neural process
nervous system process
A organ system process carried out by any of the organs or tissues of neurological system.
GOC:ai
GOC:mtg_cardio
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0051869
physiological response to stimulus
biological_process
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GOC:ai
GOC:bf
Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
regulation of lipid breakdown
regulation of lipid catabolism
regulation of lipid degradation
biological_process
regulation of lipid catabolic process
Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
down regulation of lipid catabolic process
down-regulation of lipid catabolic process
downregulation of lipid catabolic process
negative regulation of lipid breakdown
negative regulation of lipid catabolism
negative regulation of lipid degradation
inhibition of lipid catabolic process
biological_process
negative regulation of lipid catabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
positive regulation of lipid breakdown
positive regulation of lipid catabolism
positive regulation of lipid degradation
up regulation of lipid catabolic process
up-regulation of lipid catabolic process
upregulation of lipid catabolic process
activation of lipid catabolic process
stimulation of lipid catabolic process
biological_process
positive regulation of lipid catabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
GOC:ai
The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
DNA transport
The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
mRNA transport
The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
rRNA transport
The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
tRNA transport
The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.
molecular_function
nucleic acid transmembrane transporter activity
Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.
GOC:ai
Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other.
Reactome:R-HSA-203906
molecular_function
RNA transmembrane transporter activity
Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other.
GOC:ai
Reactome:R-HSA-203906
Exportin complex translocates pre-miRNA to cytosol
Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other.
molecular_function
tRNA transmembrane transporter activity
Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other.
GOC:ai
Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.
molecular_function
DNA transmembrane transporter activity
Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.
GOC:ai
Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
biological_process
regulation of secretion
Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
up regulation of secretion
up-regulation of secretion
upregulation of secretion
activation of secretion
stimulation of secretion
biological_process
positive regulation of secretion
Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
down regulation of secretion
down-regulation of secretion
downregulation of secretion
inhibition of secretion
biological_process
negative regulation of secretion
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
GOC:ai
Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
regulation of transport
Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of transport
up-regulation of transport
upregulation of transport
activation of transport
stimulation of transport
biological_process
positive regulation of transport
Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of transport
down-regulation of transport
downregulation of transport
inhibition of transport
biological_process
negative regulation of transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
regulation of DNA metabolism
biological_process
regulation of DNA metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.
down regulation of DNA metabolic process
down-regulation of DNA metabolic process
downregulation of DNA metabolic process
negative regulation of DNA metabolism
inhibition of DNA metabolic process
biological_process
negative regulation of DNA metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
positive regulation of DNA metabolism
up regulation of DNA metabolic process
up-regulation of DNA metabolic process
upregulation of DNA metabolic process
activation of DNA metabolic process
stimulation of DNA metabolic process
biological_process
positive regulation of DNA metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
down regulation of lipid biosynthetic process
down-regulation of lipid biosynthetic process
downregulation of lipid biosynthetic process
negative regulation of lipid anabolism
negative regulation of lipid biosynthesis
negative regulation of lipid formation
negative regulation of lipid synthesis
negative regulation of lipogenesis
inhibition of lipid biosynthetic process
biological_process
negative regulation of lipid biosynthetic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
GOC:ai
negative regulation of lipogenesis
GOC:sl
The controlled breakdown of the nuclear envelope in the context of a normal process.
nuclear envelope breakdown
nuclear envelope catabolism
nuclear envelope degradation
biological_process
nuclear envelope disassembly
The controlled breakdown of the nuclear envelope in the context of a normal process.
GOC:ai
Interacting selectively and non-covalently with an unfolded protein.
binding unfolded ER proteins
fimbrium-specific chaperone activity
glycoprotein-specific chaperone activity
histone-specific chaperone activity
ribosomal chaperone activity
tubulin-specific chaperone activity
molecular_function
chaperone activity
unfolded protein binding
Interacting selectively and non-covalently with an unfolded protein.
GOC:ai
Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
GO:1904167
GO:2000823
regulation of transcription factor activity
regulation of DNA binding transcription factor activity
regulation of sequence-specific DNA binding transcription factor activity
regulation of androgen receptor activity
regulation of thyroid hormone receptor activity
biological_process
regulation of DNA-binding transcription factor activity
Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
GOC:ai
regulation of transcription factor activity
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
rph
2015-04-22T12:22:16Z
GO:1904169
positive regulation of transcription factor activity
positive regulation of DNA binding transcription factor activity
positive regulation of sequence-specific DNA binding transcription factor activity
up regulation of transcription factor activity
up-regulation of transcription factor activity
upregulation of transcription factor activity
activation of transcription factor activity
positive regulation of thyroid hormone receptor activity
stimulation of transcription factor activity
biological_process
positive regulation of DNA-binding transcription factor activity
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
GOC:ai
positive regulation of transcription factor activity
GOC:dph
GOC:tb
Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
down regulation of developmental process
down-regulation of developmental process
downregulation of developmental process
inhibition of developmental process
biological_process
negative regulation of developmental process
Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GOC:ai
Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
up regulation of developmental process
up-regulation of developmental process
upregulation of developmental process
activation of developmental process
stimulation of developmental process
biological_process
positive regulation of developmental process
Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GOC:ai
Any process that modulates the frequency, rate or extent of helicase activity.
biological_process
regulation of helicase activity
Any process that modulates the frequency, rate or extent of helicase activity.
GOC:ai
Any process that activates or increases the activity of a helicase.
up regulation of helicase activity
up-regulation of helicase activity
upregulation of helicase activity
activation of helicase activity
stimulation of helicase activity
biological_process
positive regulation of helicase activity
Any process that activates or increases the activity of a helicase.
GOC:ai
Any process that stops or reduces the activity of a helicase.
down regulation of helicase activity
down-regulation of helicase activity
downregulation of helicase activity
inhibition of helicase activity
biological_process
negative regulation of helicase activity
Any process that stops or reduces the activity of a helicase.
GOC:ai
Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
biological_process
regulation of binding
Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
GOC:ai
Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
up regulation of binding
up-regulation of binding
upregulation of binding
activation of binding
stimulation of binding
biological_process
positive regulation of binding
Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
GOC:ai
Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
down regulation of binding
down-regulation of binding
downregulation of binding
inhibition of binding
biological_process
negative regulation of binding
Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
GOC:ai
Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
biological_process
regulation of DNA binding
Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GOC:ai
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
regulation of cellular component organisation
biological_process
regulation of cell organisation
regulation of cell organization
regulation of cellular component organization and biogenesis
regulation of cellular component organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GOC:ai
regulation of cell organisation
GOC:mah
regulation of cell organization
GOC:mah
regulation of cellular component organization and biogenesis
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
down regulation of cell organization
down-regulation of cell organization
downregulation of cell organization
inhibition of cell organization
biological_process
negative regulation of cell organisation
negative regulation of cellular component organization and biogenesis
negative regulation of cellular component organization
Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GOC:ai
negative regulation of cell organisation
GOC:mah
negative regulation of cellular component organization and biogenesis
GOC:mah
Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
positive regulation of cell organisation
up regulation of cell organization
up-regulation of cell organization
upregulation of cell organization
activation of cell organization
stimulation of cell organization
biological_process
positive regulation of cellular component organization and biogenesis
positive regulation of cellular component organization
Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GOC:ai
positive regulation of cellular component organization and biogenesis
GOC:mah
The directed movement of substances out of the nucleus.
export from nucleus
nucleus export
substance nuclear export
biological_process
nuclear export
The directed movement of substances out of the nucleus.
GOC:ai
The directed movement of substances into, out of, or within the nucleus.
Wikipedia:Nuclear_transport
nucleus transport
biological_process
nuclear transport
The directed movement of substances into, out of, or within the nucleus.
GOC:ai
The directed movement of substances into the nucleus.
jl
2013-12-19T15:26:34Z
GO:1902593
nuclear import
single organism nuclear import
substance nuclear import
biological_process
single-organism nuclear import
import into nucleus
The directed movement of substances into the nucleus.
GOC:ai
single organism nuclear import
GOC:TermGenie
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
regulation of nitrogen metabolic process
regulation of nitrogen metabolism
biological_process
regulation of nitrogen compound metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
GOC:ai
GOC:tb
regulation of nitrogen metabolic process
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
down regulation of nitrogen metabolic process
down-regulation of nitrogen metabolic process
downregulation of nitrogen metabolic process
negative regulation of nitrogen metabolic process
negative regulation of nitrogen metabolism
inhibition of nitrogen metabolic process
biological_process
negative regulation of nitrogen compound metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
GOC:ai
GOC:tb
negative regulation of nitrogen metabolic process
GOC:tb
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
positive regulation of nitrogen metabolic process
positive regulation of nitrogen metabolism
up regulation of nitrogen metabolic process
up-regulation of nitrogen metabolic process
upregulation of nitrogen metabolic process
activation of nitrogen metabolic process
stimulation of nitrogen metabolic process
biological_process
positive regulation of nitrogen compound metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
GOC:ai
GOC:tb
positive regulation of nitrogen metabolic process
GOC:tb
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
down regulation of sulfur metabolic process
down-regulation of sulfur metabolic process
downregulation of sulfur metabolic process
negative regulation of sulfur metabolism
negative regulation of sulphur metabolic process
negative regulation of sulphur metabolism
inhibition of sulfur metabolic process
biological_process
negative regulation of sulfur metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
positive regulation of sulfur metabolism
positive regulation of sulphur metabolic process
positive regulation of sulphur metabolism
up regulation of sulfur metabolic process
up-regulation of sulfur metabolic process
upregulation of sulfur metabolic process
activation of sulfur metabolic process
stimulation of sulfur metabolic process
biological_process
positive regulation of sulfur metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
GOC:ai
Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
jl
2013-12-18T13:51:04Z
GO:1902578
establishment and maintenance of localization
establishment and maintenance of position
localisation
establishment and maintenance of cellular component location
establishment and maintenance of substance location
establishment and maintenance of substrate location
biological_process
single organism localization
single-organism localization
localization
Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GOC:ai
GOC:dos
localisation
GOC:mah
single organism localization
GOC:TermGenie
The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein.
vitamin or cofactor transport
biological_process
cofactor transport
The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein.
GOC:ai
Enables the transfer of a cofactor from one side of a membrane to the other. A cofactor is a substance that is required for the activity of an enzyme or other protein.
vitamin or cofactor transporter activity
molecular_function
cofactor transporter activity
cofactor transmembrane transporter activity
GO_REF:0000090
Enables the transfer of a cofactor from one side of a membrane to the other. A cofactor is a substance that is required for the activity of an enzyme or other protein.
GOC:ai
The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
cofactor metabolism
biological_process
cofactor metabolic process
The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
GOC:ai
The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein.
cofactor breakdown
cofactor catabolism
cofactor degradation
biological_process
cofactor catabolic process
The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein.
GOC:ai
The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein.
cofactor anabolism
cofactor biosynthesis
cofactor formation
cofactor synthesis
biological_process
cofactor biosynthetic process
The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein.
GOC:ai
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
regulation of cofactor metabolism
biological_process
regulation of cofactor metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
positive regulation of cofactor metabolism
up regulation of cofactor metabolic process
up-regulation of cofactor metabolic process
upregulation of cofactor metabolic process
activation of cofactor metabolic process
stimulation of cofactor metabolic process
biological_process
positive regulation of cofactor metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
down regulation of cofactor metabolic process
down-regulation of cofactor metabolic process
downregulation of cofactor metabolic process
negative regulation of cofactor metabolism
inhibition of cofactor metabolic process
biological_process
negative regulation of cofactor metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of protein transport
up-regulation of protein transport
upregulation of protein transport
activation of protein transport
stimulation of protein transport
biological_process
positive regulation of protein transport
Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
regulation of protein transport
Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of protein transport
down-regulation of protein transport
downregulation of protein transport
inhibition of protein transport
biological_process
negative regulation of protein transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
establishment of localisation
biological_process
establishment of localization
Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GOC:ai
GOC:dos
establishment of localisation
GOC:mah
The directed movement of RNA to a specific location.
RNA positioning
RNA recruitment
establishment of RNA localisation
biological_process
establishment of RNA localization
The directed movement of RNA to a specific location.
GOC:ai
establishment of RNA localisation
GOC:mah
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
biological_process
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
GOC:ai
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
up regulation of multicellular organismal process
up-regulation of multicellular organismal process
upregulation of multicellular organismal process
activation of multicellular organismal process
stimulation of multicellular organismal process
biological_process
positive regulation of multicellular organismal process
Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
down regulation of multicellular organismal process
down-regulation of multicellular organismal process
downregulation of multicellular organismal process
inhibition of multicellular organismal process
biological_process
negative regulation of multicellular organismal process
Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
GOC:ai
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
regulation of protein metabolism
biological_process
regulation of protein metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
positive regulation of protein metabolism
up regulation of protein metabolic process
up-regulation of protein metabolic process
upregulation of protein metabolic process
activation of protein metabolic process
stimulation of protein metabolic process
biological_process
positive regulation of protein metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.
down regulation of protein metabolic process
down-regulation of protein metabolic process
downregulation of protein metabolic process
negative regulation of protein metabolism
inhibition of protein metabolic process
biological_process
negative regulation of protein metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.
GOC:ai
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
regulation of RNA metabolism
biological_process
regulation of RNA metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.
down regulation of RNA metabolic process
down-regulation of RNA metabolic process
downregulation of RNA metabolic process
negative regulation of RNA metabolism
inhibition of RNA metabolic process
biological_process
negative regulation of RNA metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GOC:ai
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.
positive regulation of RNA metabolism
up regulation of RNA metabolic process
up-regulation of RNA metabolic process
upregulation of RNA metabolic process
activation of RNA metabolic process
stimulation of RNA metabolic process
biological_process
positive regulation of RNA metabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.
GOC:ai
The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.
protein polymer biosynthesis
protein polymer biosynthetic process
protein polymer formation
biological_process
protein polymerization
The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.
GOC:ai
The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.
protein polymer breakdown
protein polymer catabolic process
protein polymer catabolism
protein polymer degradation
biological_process
protein depolymerization
The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.
GOC:ai
Any process that modulates the frequency, rate or extent of the movement of a cellular component.
regulation of cellular component motion
biological_process
regulation of cell movement
regulation of cellular component movement
Any process that modulates the frequency, rate or extent of the movement of a cellular component.
GOC:ai
GOC:dph
GOC:jl
regulation of cellular component motion
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component.
negative regulation of cellular component motion
biological_process
negative regulation of cellular component movement
Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component.
GOC:ai
GOC:dph
GOC:jl
negative regulation of cellular component motion
GOC:mah
Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.
positive regulation of cellular component motion
biological_process
positive regulation of cellular component movement
Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.
GOC:ai
GOC:dph
GOC:jl
positive regulation of cellular component motion
GOC:mah
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
GO:0007001
GO:0051277
chromosome organisation
biological_process
chromosome organization and biogenesis
maintenance of genome integrity
nuclear genome maintenance
chromosome organization
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
GOC:ai
GOC:dph
GOC:jl
GOC:mah
chromosome organization and biogenesis
GOC:mah
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
Wikipedia:Cell_division
biological_process
Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division.
cell division
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
GOC:di
GOC:go_curators
GOC:pr
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
biological_process
regulation of cell division
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
GOC:go_curators
The directed movement of a chromosome to a specific location.
chromosome positioning
establishment of chromosome localisation
biological_process
establishment of chromosome localization
The directed movement of a chromosome to a specific location.
GOC:ai
establishment of chromosome localisation
GOC:mah
Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
hydrolase regulator
biological_process
regulation of hydrolase activity
Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
EC:3.-.-.-
GOC:ai
Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
transferase regulator
biological_process
This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
regulation of transferase activity
Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
EC:2.-.-.-
GOC:ai
Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
lyase regulator
biological_process
regulation of lyase activity
Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
EC:4.-.-.-
GOC:ai
Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.
ligase regulator
biological_process
regulation of ligase activity
Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.
EC:6.-.-.-
GOC:ai
Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
oxidoreductase regulator
biological_process
regulation of oxidoreductase activity
Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
EC:1.-.-.-
GOC:ai
Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.
hydrolase activator
up regulation of hydrolase activity
up-regulation of hydrolase activity
upregulation of hydrolase activity
activation of hydrolase activity
stimulation of hydrolase activity
biological_process
positive regulation of hydrolase activity
Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.
GOC:ai
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
down regulation of hydrolase activity
down-regulation of hydrolase activity
downregulation of hydrolase activity
hydrolase inhibitor
inhibition of hydrolase activity
biological_process
negative regulation of hydrolase activity
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
GOC:ai
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
transferase activator
up regulation of transferase activity
up-regulation of transferase activity
upregulation of transferase activity
activation of transferase activity
stimulation of transferase activity
biological_process
This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
positive regulation of transferase activity
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
GOC:ai
Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
down regulation of transferase activity
down-regulation of transferase activity
downregulation of transferase activity
transferase inhibitor
inhibition of transferase activity
biological_process
This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
negative regulation of transferase activity
Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
GOC:ai
Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
lyase activator
up regulation of lyase activity
up-regulation of lyase activity
upregulation of lyase activity
activation of lyase activity
stimulation of lyase activity
biological_process
positive regulation of lyase activity
Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
GOC:ai
Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
down regulation of lyase activity
down-regulation of lyase activity
downregulation of lyase activity
lyase inhibitor
inhibition of lyase activity
biological_process
negative regulation of lyase activity
Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
GOC:ai
Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
ligase activator
up regulation of ligase activity
up-regulation of ligase activity
upregulation of ligase activity
activation of ligase activity
stimulation of ligase activity
biological_process
positive regulation of ligase activity
Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
GOC:ai
Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
down regulation of ligase activity
down-regulation of ligase activity
downregulation of ligase activity
ligase inhibitor
inhibition of ligase activity
biological_process
negative regulation of ligase activity
Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
GOC:ai
Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
GO:0009391
oxidoreductase activator
up regulation of oxidoreductase activity
up-regulation of oxidoreductase activity
upregulation of oxidoreductase activity
activation of oxidoreductase activity
ribonucleotide reductase activating enzyme activity
stimulation of oxidoreductase activity
biological_process
positive regulation of oxidoreductase activity
Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
GOC:ai
Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
down regulation of oxidoreductase activity
down-regulation of oxidoreductase activity
downregulation of oxidoreductase activity
oxidoreductase inhibitor
inhibition of oxidoreductase activity
biological_process
negative regulation of oxidoreductase activity
Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
GOC:ai
The 'de novo' formation of a microtubule, mediated by the microtubule organizing center.
MTOC-mediated microtubule nucleation
microtubule nucleation by MTOC
microtubule nucleation by microtubule organising centre
microtubule organizing center-mediated microtubule nucleation
biological_process
microtubule nucleation by microtubule organizing center
The 'de novo' formation of a microtubule, mediated by the microtubule organizing center.
GOC:ai
The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.
GO:0042146
biological_process
heterotypic vacuole fusion (non-autophagic)
heterotypic vacuole fusion, non-autophagic
vesicle fusion with vacuole
The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.
GOC:ai
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
regulation of cytoskeleton organisation
biological_process
regulation of cytoskeleton organization and biogenesis
regulation of cytoskeleton organization
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GOC:ai
regulation of cytoskeleton organisation
GOC:mah
regulation of cytoskeleton organization and biogenesis
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
down regulation of cytoskeleton organization
down-regulation of cytoskeleton organization
downregulation of cytoskeleton organization
negative regulation of cytoskeleton organisation
inhibition of cytoskeleton organization
biological_process
negative regulation of cytoskeleton organization and biogenesis
negative regulation of cytoskeleton organization
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GOC:ai
negative regulation of cytoskeleton organisation
GOC:mah
negative regulation of cytoskeleton organization and biogenesis
GOC:mah
Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
positive regulation of cytoskeleton organisation
up regulation of cytoskeleton organization
up-regulation of cytoskeleton organization
upregulation of cytoskeleton organization
activation of cytoskeleton organization
stimulation of cytoskeleton organization
biological_process
positive regulation of cytoskeleton organization and biogenesis
positive regulation of cytoskeleton organization
Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GOC:ai
positive regulation of cytoskeleton organisation
GOC:mah
positive regulation of cytoskeleton organization and biogenesis
GOC:mah
The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
peptidolysis involved in cellular protein catabolic process
peptidolysis involved in cellular protein catabolism
biological_process
peptidolysis during cellular protein catabolic process
peptidolysis during cellular protein catabolism
proteolysis during cellular protein catabolic process
proteolysis during cellular protein catabolism
proteolysis involved in cellular protein catabolic process
The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
GOC:ai
GOC:dph
GOC:tb
Any process leading to the attainment of the full functional capacity of a protein.
biological_process
protein maturation
Any process leading to the attainment of the full functional capacity of a protein.
GOC:ai
Any process in which an organelle is transported to, and/or maintained in, a specific location.
establishment and maintenance of organelle localization
organelle localisation
biological_process
organelle localization
Any process in which an organelle is transported to, and/or maintained in, a specific location.
GOC:ai
organelle localisation
GOC:mah
A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
jl
2013-12-18T14:04:32Z
GO:1902580
cellular localisation
establishment and maintenance of cellular localization
establishment and maintenance of localization in cell or cell membrane
single organism cellular localization
intracellular localization
localization within cell
biological_process
single-organism cellular localization
cellular localization
A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
GOC:tb
GOC:vw
cellular localisation
GOC:mah
single organism cellular localization
GOC:TermGenie
Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell.
ER localization
endoplasmic reticulum localisation
establishment and maintenance of ER localization
biological_process
endoplasmic reticulum localization
Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell.
GOC:ai
ER localization
GOC:dph
endoplasmic reticulum localisation
GOC:mah
Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell.
establishment and maintenance of plastid localization
plastid localisation
biological_process
plastid localization
Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell.
GOC:ai
plastid localisation
GOC:mah
Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.
Golgi apparatus localization
Golgi body localization
Golgi localisation
establishment and maintenance of Golgi localization
biological_process
Golgi localization
Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.
GOC:ai
Golgi localisation
GOC:mah
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
establishment and maintenance of mitochondria localization
establishment and maintenance of mitochondrion localization
localization of mitochondria
localization of mitochondrion
mitochondria localization
mitochondrial localization
mitochondrion localisation
biological_process
mitochondrion localization
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
GOC:ai
mitochondrion localisation
GOC:mah
Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.
cell nucleus localization
establishment and maintenance of nucleus localization
localization of nucleus
nucleus localisation
biological_process
nucleus localization
Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.
GOC:ai
nucleus localisation
GOC:mah
Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.
cytoplasmic vesicle localization
establishment and maintenance of vesicle localization
vesicle localisation
biological_process
vesicle localization
Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.
GOC:ai
vesicle localisation
GOC:mah
Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
establishment of localisation in cell
establishment of intracellular localization
establishment of localization within cell
positioning within cell
biological_process
establishment of cellular localization
establishment of localization in cell
Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GOC:ai
GOC:dos
GOC:dph
GOC:tb
establishment of localisation in cell
GOC:mah
establishment of cellular localization
GOC:dph
GOC:tb
The directed movement of a vesicle to a specific location.
establishment of vesicle localisation
biological_process
establishment of vesicle localization
The directed movement of a vesicle to a specific location.
GOC:ai
establishment of vesicle localisation
GOC:mah
The directed movement of the mitochondrion to a specific location.
establishment of mitochondria localization
establishment of mitochondrion localisation
mitochondria positioning
mitochondrial migration
mitochondrion positioning
biological_process
establishment of mitochondrion localization
The directed movement of the mitochondrion to a specific location.
GOC:ai
establishment of mitochondrion localisation
GOC:mah
The directed movement of an organelle to a specific location.
establishment of organelle localisation
biological_process
establishment of organelle localization
The directed movement of an organelle to a specific location.
GOC:ai
establishment of organelle localisation
GOC:mah
The directed movement of a plastid to a specific location in the cell.
establishment of plastid localisation
biological_process
establishment of plastid localization
The directed movement of a plastid to a specific location in the cell.
GOC:ai
establishment of plastid localisation
GOC:mah
Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.
establishment and maintenance of localization in membrane
establishment and maintenance of position in membrane
localisation within membrane
localization to membrane
positioning within membrane
biological_process
localization within membrane
Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.
GOC:ai
localisation within membrane
GOC:mah
Any process in which a cell is transported to, and/or maintained in, a specific location.
cell localization
establishment and maintenance of cell localization
establishment and maintenance of localization of cell
localisation of cell
biological_process
localization of cell
Any process in which a cell is transported to, and/or maintained in, a specific location.
GOC:ai
localisation of cell
GOC:mah
The directed movement of the Golgi to a specific location.
establishment of Golgi apparatus localization
establishment of Golgi body localization
establishment of Golgi localisation
biological_process
establishment of Golgi localization
The directed movement of the Golgi to a specific location.
GOC:ai
establishment of Golgi localisation
GOC:mah
The directed movement of the endoplasmic reticulum to a specific location.
establishment of ER localisation
establishment of endoplasmic reticulum localization
biological_process
establishment of ER localization
The directed movement of the endoplasmic reticulum to a specific location.
GOC:ai
establishment of ER localisation
GOC:mah
A biological process which involves another organism of the same or different species.
GO:0051706
interaction between organisms
physiological interaction between organisms
physiological interaction with other organism
biological_process
multi-organism process
A biological process which involves another organism of the same or different species.
GOC:jl
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
biological_process
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GOC:bf
GOC:jl
Any process that modulates the rate or extent of progression through the cell cycle.
GO:0000074
cell cycle modulation
cell cycle regulation
control of cell cycle progression
modulation of cell cycle progression
regulation of cell cycle progression
regulation of progression through cell cycle
biological_process
cell cycle regulator
tumor suppressor
regulation of cell cycle
Any process that modulates the rate or extent of progression through the cell cycle.
GOC:ai
GOC:dph
GOC:tb
Any process that activates or increases the frequency, rate or extent of cell division.
up regulation of cell division
up-regulation of cell division
upregulation of cell division
activation of cell division
stimulation of cell division
biological_process
positive regulation of cell division
Any process that activates or increases the frequency, rate or extent of cell division.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.
down regulation of cell division
down-regulation of cell division
downregulation of cell division
inhibition of cell division
biological_process
negative regulation of cell division
Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.
GOC:ai
Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
biological_process
regulation of nuclear division
Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
down regulation of nuclear division
down-regulation of nuclear division
downregulation of nuclear division
inhibition of nuclear division
biological_process
negative regulation of nuclear division
Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
GOC:ai
Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
up regulation of nuclear division
up-regulation of nuclear division
upregulation of nuclear division
activation of nuclear division
stimulation of nuclear division
biological_process
positive regulation of nuclear division
Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
GOC:ai
Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
biological_process
regulation of amine transport
Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of amine transport
down-regulation of amine transport
downregulation of amine transport
inhibition of amine transport
biological_process
negative regulation of amine transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
up regulation of amine transport
up-regulation of amine transport
upregulation of amine transport
activation of amine transport
stimulation of amine transport
biological_process
positive regulation of amine transport
Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:ai
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
biological_process
regulation of nervous system development
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
down regulation of nervous system development
down-regulation of nervous system development
downregulation of nervous system development
inhibition of nervous system development
biological_process
negative regulation of nervous system development
Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
GOC:ai
Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
up regulation of nervous system development
up-regulation of nervous system development
upregulation of nervous system development
activation of nervous system development
stimulation of nervous system development
biological_process
positive regulation of nervous system development
Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
GOC:ai
Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
biological_process
regulation of chromosome segregation
Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
GOC:ai
Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
up regulation of chromosome segregation
up-regulation of chromosome segregation
upregulation of chromosome segregation
activation of chromosome segregation
stimulation of chromosome segregation
biological_process
positive regulation of chromosome segregation
Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
GOC:ai
Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
down regulation of chromosome segregation
down-regulation of chromosome segregation
downregulation of chromosome segregation
inhibition of chromosome segregation
biological_process
negative regulation of chromosome segregation
Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
GOC:ai
Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
biological_process
peptidase regulator activity
regulation of peptidase activity
Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
GOC:ai
Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
protease regulator activity
biological_process
regulation of endopeptidase activity
Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
GOC:ai
GOC:hjd
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
tanyaberardini
2015-10-21T13:22:47Z
GO:0090662
membrane transport
ATP hydrolysis coupled transmembrane transport
biological_process
Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes.
transmembrane transport
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
GOC:dph
GOC:jid
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
Wikipedia:Redox
oxidation reduction
oxidoreductase process
biological_process
oxidation-reduction process
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GOC:dhl
GOC:ecd
GOC:jh2
GOC:jid
GOC:mlg
GOC:rph
oxidoreductase process
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
GO:0032947
binding, bridging
molecular_function
protein complex scaffold activity
protein-containing complex scaffold activity
molecular adaptor activity
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
GOC:mtg_MIT_16mar07
GOC:vw
Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
peroxisome localisation
biological_process
peroxisome localization
Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
GOC:dph
PMID:16449325
peroxisome localisation
GOC:mah
The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
microtubule-based peroxisome localisation
biological_process
microtubule-based peroxisome localization
The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
GOC:dph
PMID:16449325
microtubule-based peroxisome localisation
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biological_process
regulation of macromolecule metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GOC:dph
GOC:tb
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GO:0042384
Reactome:R-HSA-5617833.2
ciliogenesis
cilium assembly
cilium formation
microtubule-based flagellum assembly
biological_process
cilium biogenesis
cilium morphogenesis
cilium organization
Note that we deem cilium and microtubule-based flagellum to be equivalent.
cilium assembly
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
GOC:BHF
GOC:cilia
GOC:dph
GOC:kmv
GOC:pr
GOC:vw
ISBN:0198506732
PMID:13978319
PMID:27350441
Reactome:R-HSA-5617833.2
cilium biogenesis
GOC:mah
cilium organization
GOC:dph
Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
biological_process
regulation of cell development
Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.
regulation of cellular localisation
biological_process
regulation of cellular localization
Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.
GOC:dph
GOC:tb
regulation of cellular localisation
GOC:mah
The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.
biological_process
axonemal microtubule depolymerization
The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.
GOC:cilia
GOC:dph
GOC:krc
GOC:tb
Any process that modulates the rate, frequency, or extent of cell projection assembly.
biological_process
regulation of cell projection formation
regulation of cell projection assembly
Any process that modulates the rate, frequency, or extent of cell projection assembly.
GOC:dph
GOC:tb
regulation of cell projection formation
GOC:dph
GOC:tb
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
dph
2009-04-13T01:56:10Z
biological_process
negative regulation of cell death
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
GOC:BHF
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
dph
2009-05-18T02:29:43Z
biological_process
regulation of vesicle-mediated transport
Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
dph
2009-05-18T02:37:00Z
biological_process
regulation of ER to Golgi vesicle-mediated transport
Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.
dph
2009-05-18T03:07:02Z
biological_process
regulation of microtubule-based movement
Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
dph
2010-01-29T01:48:10Z
biological_process
regulation of mRNA decay
regulation of mRNA catabolic process
Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GOC:ascb_2009
GOC:dph
GOC:tb
regulation of mRNA decay
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
dph
2010-01-29T01:58:03Z
biological_process
positive regulation of mRNA decay
positive regulation of mRNA catabolic process
Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
GOC:ascb_2009
GOC:dph
GOC:tb
positive regulation of mRNA decay
GOC:ascb_2009
GOC:dph
GOC:tb
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
janelomax
2010-02-08T02:43:11Z
GO:0016044
GO:0044802
cellular membrane organisation
cellular membrane organization
membrane organisation
biological_process
membrane organization and biogenesis
single-organism membrane organization
membrane organization
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GOC:dph
GOC:tb
membrane organisation
GOC:mah
membrane organization and biogenesis
GOC:mah
The membrane organization process that joins two lipid bilayers to form a single membrane.
janelomax
2010-02-08T02:48:06Z
GO:0006944
GO:0044801
Wikipedia:Lipid_bilayer_fusion
cellular membrane fusion
biological_process
single-organism membrane fusion
membrane fusion
The membrane organization process that joins two lipid bilayers to form a single membrane.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
dph
2010-05-17T01:33:20Z
biological_process
regulation of proteasomal protein catabolic process
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
GOC:dph
GOC:tb
A process in which a protein is transported to, or maintained in, a location within a lysosome.
dph
2012-10-05T10:50:51Z
biological_process
protein localization to lysosome
A process in which a protein is transported to, or maintained in, a location within a lysosome.
GOC:dph
A process in which a protein is transported to, or maintained in, a location within a cilium.
dph
2013-03-22T15:41:44Z
biological_process
protein localization to cilium
A process in which a protein is transported to, or maintained in, a location within a cilium.
GOC:dph
A cellular process that results in the breakdown of a cilium.
dph
2013-04-18T14:59:59Z
cilium resorption
biological_process
Note that we deem cilium and microtubule-based flagellum to be equivalent.
cilium disassembly
A cellular process that results in the breakdown of a cilium.
GOC:cilia
GOC:dph
PMID:17604723
PMID:27350441
cilium resorption
GOC:dph
Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
https://github.com/geneontology/go-ontology/issues/14336
dph
2014-03-03T07:58:18Z
molecular_function
importin activity
nuclear import signal receptor activity
Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
GOC:dph
GOC:pg
GOC:vw
PMID:28713609
Wikipedia:Nuclear_transport
The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits.
dph
2014-11-07T15:32:20Z
biological_process
mitochondrial ribosome assembly
The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits.
GOC:dph
A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
dph
2015-05-06T11:22:38Z
cellular_component
transferase complex, transferring phosphorus-containing groups
A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GOC:bhm
GOC:dph
The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.
dph
2015-07-08T13:42:15Z
biological_process
cytosolic lipolysis
The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.
GOC:autophagy
The disaggregation of a mitochondrion into its constituent components.
dph
2015-07-08T13:59:16Z
mitochondrion degradation
biological_process
mitochondrion disassembly
The disaggregation of a mitochondrion into its constituent components.
GOC:autophagy
PMID:25009776
mitochondrion degradation
GOC:autophagy
Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell.
MTOC localization
MTOC polarity
microtubule organizing center polarity
biological_process
microtubule organizing center localization
Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell.
PMID:21281821
A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.
dph
2017-07-13T19:42:14Z
biological_process
process utilizing autophagic mechanism
A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.
PMID:21997368
PMID:22966490
PMID:28596378
The directed movement of a protein to a specific location in a plasma membrane.
dph
2017-10-26T12:55:15Z
biological_process
establishment of protein localization to plasma membrane
The directed movement of a protein to a specific location in a plasma membrane.
GOC:dph
GOC:vw
Any process that modulates the rate, frequency or extent of a small molecule metabolic process.
dph
2018-03-19T14:11:54Z
regulation of small molecule metabolism
biological_process
regulation of small molecule metabolic process
Any process that modulates the rate, frequency or extent of a small molecule metabolic process.
GOC:vw
Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.
dph
2018-03-19T14:25:10Z
positive regulation of small molecule metabolism
biological_process
positive regulation of small molecule metabolic process
Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.
GOC:vw
Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.
dph
2018-03-19T14:27:23Z
negative regulation of small molecule metabolism
biological_process
negative regulation of small molecule metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.
GOC:vw
Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA).
dph
2019-05-30T16:45:04Z
biological_process
regulation of mitochondrial gene expression
Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA).
PMID:28285835
The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
intracellular membrane translocation of a protein
intracellular protein membrane transport
intracellular protein transport across a membrane
biological_process
Note that this term is not intended for use in annotating lateral movement within membranes.
intracellular protein transmembrane transport
The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
GOC:isa_complete
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
GO:0006461
biological_process
chaperone activity
macromolecular complex assembly
macromolecule complex assembly
protein complex assembly
protein complex formation
protein-containing complex assembly
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
GOC:jl
Any process that modulates a measurable attribute of any biological process, quality or function.
regulation
biological_process
biological regulation
Any process that modulates a measurable attribute of any biological process, quality or function.
GOC:dph
GOC:isa_complete
GOC:mah
GOC:pr
GOC:vw
Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
regulation of biological attribute
regulation of biological characteristic
biological_process
regulation of biological quality
Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
GOC:dph
GOC:isa_complete
GOC:mah
GOC:pr
GOC:vw
Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
regulation of a molecular function
biological_process
regulation of molecular function
Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GOC:isa_complete
Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
Reactome:R-HSA-3065958
Reactome:R-HSA-3065959
Reactome:R-HSA-4167501
Reactome:R-HSA-6803060
molecular_function
peptidase activity, acting on L-amino acid peptides
Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
GOC:mah
Reactome:R-HSA-3065958
An unknown protease degrades ACACA
Reactome:R-HSA-3065959
An unknown protease degrades hCBXs
Reactome:R-HSA-4167501
An unknown protease degrades ACACB
Reactome:R-HSA-6803060
DCD(63-110) is processed to DCD(63-109)
An organelle lumen that is part of an intracellular organelle.
cellular_component
intracellular organelle lumen
An organelle lumen that is part of an intracellular organelle.
GOC:mah
The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
mitochondrial translation initiation
biological_process
mitochondrial translational initiation
The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
GOC:mah
mitochondrial translation initiation
GOC:mah
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
mitochondrial translation elongation
biological_process
mitochondrial translational elongation
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
GOC:mah
mitochondrial translation elongation
GOC:mah
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
mitochondrial translation termination
biological_process
mitochondrial translational termination
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
GOC:mah
http://mitogenome.org/index.php/Genetic_Code_of_mitochondria
mitochondrial translation termination
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
regulation of mitochondrial protein anabolism
regulation of mitochondrial protein biosynthesis
regulation of mitochondrial protein formation
regulation of mitochondrial protein synthesis
biological_process
regulation of mitochondrial translation
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
GOC:mah
regulation of mitochondrial protein anabolism
GOC:mah
regulation of mitochondrial protein biosynthesis
GOC:mah
regulation of mitochondrial protein formation
GOC:mah
regulation of mitochondrial protein synthesis
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
negative regulation of mitochondrial protein anabolism
negative regulation of mitochondrial protein biosynthesis
negative regulation of mitochondrial protein formation
negative regulation of mitochondrial protein synthesis
biological_process
negative regulation of mitochondrial translation
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
GOC:mah
negative regulation of mitochondrial protein anabolism
GOC:mah
negative regulation of mitochondrial protein biosynthesis
GOC:mah
negative regulation of mitochondrial protein formation
GOC:mah
negative regulation of mitochondrial protein synthesis
GOC:mah
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
positive regulation of mitochondrial protein anabolism
positive regulation of mitochondrial protein biosynthesis
positive regulation of mitochondrial protein formation
positive regulation of mitochondrial protein synthesis
biological_process
positive regulation of mitochondrial translation
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
GOC:mah
positive regulation of mitochondrial protein anabolism
GOC:mah
positive regulation of mitochondrial protein biosynthesis
GOC:mah
positive regulation of mitochondrial protein formation
GOC:mah
positive regulation of mitochondrial protein synthesis
GOC:mah
Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
regulation of mitochondrial translation initiation
biological_process
regulation of mitochondrial translational initiation
Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
GOC:mah
regulation of mitochondrial translation initiation
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
negative regulation of mitochondrial translation initiation
biological_process
negative regulation of mitochondrial translational initiation
Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
GOC:mah
negative regulation of mitochondrial translation initiation
GOC:mah
Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
positive regulation of mitochondrial translation initiation
biological_process
positive regulation of mitochondrial translational initiation
Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
GOC:mah
positive regulation of mitochondrial translation initiation
GOC:mah
The directed movement of a protein to a specific location on a chromosome.
establishment of protein localisation to chromosome
biological_process
establishment of protein localization to chromosome
The directed movement of a protein to a specific location on a chromosome.
GOC:BHF
GOC:mah
establishment of protein localisation to chromosome
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.
regulation of establishment of protein localisation
biological_process
regulation of establishment of protein localization
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.
GOC:BHF
GOC:mah
regulation of establishment of protein localisation
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.
regulation of establishment of protein localisation to chromosome
biological_process
regulation of establishment of protein localization to chromosome
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.
GOC:BHF
GOC:mah
regulation of establishment of protein localisation to chromosome
GOC:mah
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
regulation of microtubule cytoskeleton organisation
regulation of microtubule dynamics
biological_process
regulation of microtubule cytoskeleton organization
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
GOC:mah
regulation of microtubule cytoskeleton organisation
GOC:mah
regulation of microtubule dynamics
GOC:dph
GOC:tb
A process in which a protein is transported to, or maintained in, a location within the mitochondrion.
midori
2009-04-24T02:31:18Z
protein localisation in mitochondrion
protein localization in mitochondrion
biological_process
protein localization to mitochondrion
A process in which a protein is transported to, or maintained in, a location within the mitochondrion.
GOC:ecd
protein localisation in mitochondrion
GOC:mah
The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component.
midori
2009-04-28T11:01:25Z
cellular component macromolecule biosynthesis
biological_process
cellular component macromolecule biosynthetic process
The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component.
GOC:mah
cellular component macromolecule biosynthesis
GOC:mah
Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation.
midori
2009-05-01T04:38:58Z
molecular_function
proteasome binding
Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation.
GOC:mah
The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.
midori
2009-06-16T03:58:20Z
biological_process
cell wall assembly
The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.
GOC:mah
Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
midori
2009-06-16T04:08:29Z
cellular macromolecule localisation
biological_process
cellular macromolecule localization
Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GOC:mah
cellular macromolecule localisation
GOC:mah
Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
midori
2009-08-17T03:39:18Z
regulation of protein exit from ER
regulation of protein export from ER
regulation of protein export from endoplasmic reticulum
biological_process
regulation of protein exit from endoplasmic reticulum
Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
GOC:mah
regulation of protein exit from ER
GOC:mah
regulation of protein export from ER
GOC:mah
regulation of protein export from endoplasmic reticulum
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
midori
2009-08-17T03:45:56Z
down regulation of protein exit from endoplasmic reticulum
down-regulation of protein exit from endoplasmic reticulum
downregulation of protein exit from endoplasmic reticulum
negative regulation of protein exit from ER
negative regulation of protein export from ER
negative regulation of protein export from endoplasmic reticulum
inhibition of protein exit from endoplasmic reticulum
biological_process
negative regulation of protein exit from endoplasmic reticulum
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
GOC:mah
down regulation of protein exit from endoplasmic reticulum
GOC:mah
down-regulation of protein exit from endoplasmic reticulum
GOC:mah
downregulation of protein exit from endoplasmic reticulum
GOC:mah
negative regulation of protein exit from ER
GOC:mah
negative regulation of protein export from ER
GOC:mah
negative regulation of protein export from endoplasmic reticulum
GOC:mah
inhibition of protein exit from endoplasmic reticulum
GOC:mah
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
midori
2009-08-17T03:50:04Z
positive regulation of protein exit from ER
positive regulation of protein export from ER
positive regulation of protein export from endoplasmic reticulum
up regulation of protein exit from endoplasmic reticulum
up-regulation of protein exit from endoplasmic reticulum
upregulation of protein exit from endoplasmic reticulum
activation of protein exit from endoplasmic reticulum
stimulation of protein exit from endoplasmic reticulum
biological_process
positive regulation of protein exit from endoplasmic reticulum
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
GOC:mah
positive regulation of protein exit from ER
GOC:mah
positive regulation of protein export from ER
GOC:mah
positive regulation of protein export from endoplasmic reticulum
GOC:mah
up regulation of protein exit from endoplasmic reticulum
GOC:mah
up-regulation of protein exit from endoplasmic reticulum
GOC:mah
upregulation of protein exit from endoplasmic reticulum
GOC:mah
activation of protein exit from endoplasmic reticulum
GOC:mah
stimulation of protein exit from endoplasmic reticulum
GOC:mah
The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.
midori
2009-09-09T02:40:57Z
biological_process
cell wall macromolecule catabolic process involved in cell wall disassembly
The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.
GOC:mah
The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
midori
2009-09-15T03:00:51Z
biological_process
organelle assembly
The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GOC:mah
A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.
midori
2009-10-02T12:43:34Z
protein localisation in endoplasmic reticulum
protein localization in ER
protein localization in endoplasmic reticulum
biological_process
protein localization to endoplasmic reticulum
A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.
GOC:mah
protein localisation in endoplasmic reticulum
GOC:mah
protein localization in ER
GOC:mah
The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm.
midori
2009-11-25T02:25:27Z
biological_process
protein targeting to autophagosome
protein targeting to vacuole involved in autophagy
The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm.
GOC:mah
protein targeting to autophagosome
GOC:pad
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.
midori
2010-01-13T03:19:38Z
GO:0070882
cell wall organisation or biogenesis
cell wall organization or biogenesis at cellular level
cellular cell wall organisation or biogenesis
cellular cell wall organization or biogenesis
biological_process
cell wall organization or biogenesis
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.
GOC:mah
cell wall organisation or biogenesis
GOC:mah
cell wall organization or biogenesis at cellular level
GOC:mah
cellular cell wall organisation or biogenesis
GOC:mah
A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
midori
2010-01-13T03:33:07Z
GO:0007047
GO:0044234
cell wall organisation
cell wall organisation in other organism
cell wall organization at cellular level
cell wall organization in other organism
cellular cell wall organisation
cellular cell wall organization
biological_process
cell wall organization and biogenesis
cell wall organization
A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
GOC:mah
cell wall organisation in other organism
GOC:mah
cell wall organization at cellular level
GOC:mah
cell wall organization and biogenesis
GOC:mah
Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.
midori
2010-02-25T04:00:13Z
protein localisation in extracellular region
protein localization in extracellular region
biological_process
protein localization to extracellular region
Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.
GOC:mah
protein localisation in extracellular region
GOC:mah
The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
midori
2010-03-08T02:15:14Z
biological_process
organic substance transport
The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
GOC:mah
The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
midori
2010-03-08T03:32:18Z
organic molecular entity metabolic process
organic molecular entity metabolism
organic substance metabolism
biological_process
organic substance metabolic process
The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GOC:mah
The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
midori
2010-03-08T03:56:28Z
biological_process
nitrogen compound transport
The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
The aggregation, arrangement and bonding together of a set of components to form a membrane.
midori
2010-03-10T11:19:17Z
biological_process
membrane assembly
The aggregation, arrangement and bonding together of a set of components to form a membrane.
GOC:mah
The process in which a protein is transported across a membrane.
midori
2010-09-03T02:54:26Z
protein membrane transport
biological_process
Note that this term is not intended for use in annotating lateral movement within membranes.
protein transmembrane transport
The process in which a protein is transported across a membrane.
GOC:mah
GOC:vw
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex.
midori
2010-09-08T10:10:35Z
RNA-protein complex subunit organization
protein-RNA complex subunit organization
ribonucleoprotein complex subunit organisation
biological_process
ribonucleoprotein complex subunit organization
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex.
GOC:mah
RNA-protein complex subunit organization
GOC:mah
protein-RNA complex subunit organization
GOC:mah
ribonucleoprotein complex subunit organisation
GOC:mah
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
midori
2010-09-10T01:39:16Z
GO:0071841
cellular component organisation or biogenesis
cellular component organisation or biogenesis at cellular level
cellular component organization or biogenesis at cellular level
biological_process
cellular component organization or biogenesis
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GOC:mah
cellular component organisation or biogenesis
GOC:mah
cellular component organisation or biogenesis at cellular level
GOC:mah
The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
midori
2010-09-15T02:14:33Z
DNA anabolism
DNA biosynthesis
DNA formation
DNA synthesis
biological_process
DNA biosynthetic process
The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
GOC:mah
DNA anabolism
GOC:mah
DNA biosynthesis
GOC:mah
DNA formation
GOC:mah
DNA synthesis
GOC:mah
A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.
midori
2010-09-30T05:21:03Z
Wikipedia:Nitrogen_cycle
biological_process
nitrogen cycle metabolic process
A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.
GOC:mah
PMID:16675690
Wikipedia:Nitrogen_cycle
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
midori
2010-10-04T01:51:47Z
cellular_component
cell periphery
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
GOC:mah
The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
midori
2010-11-11T11:43:56Z
sulfur-containing compound transport
biological_process
sulfur compound transport
The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GOC:mah
sulfur-containing compound transport
GOC:mah
The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
midori
2010-12-01T04:59:11Z
microtubule-based organelle localization
biological_process
organelle transport along microtubule
The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
GOC:mah
microtubule-based organelle localization
GOC:rl
The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
midori
2011-02-14T01:56:51Z
establishment of protein localisation to organelle
biological_process
establishment of protein localization to organelle
The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
GOC:mah
establishment of protein localisation to organelle
GOC:mah
The directed movement of a protein to a specific location in the endoplasmic reticulum.
midori
2011-02-14T02:23:41Z
establishment of protein localisation to ER
establishment of protein localisation to endoplasmic reticulum
establishment of protein localization in endoplasmic reticulum
establishment of protein localization to ER
biological_process
establishment of protein localization to endoplasmic reticulum
The directed movement of a protein to a specific location in the endoplasmic reticulum.
GOC:mah
establishment of protein localisation to ER
GOC:mah
establishment of protein localisation to endoplasmic reticulum
GOC:mah
establishment of protein localization to ER
GOC:mah
The directed movement of a protein to the mitochondrion or a part of the mitochondrion.
midori
2011-02-14T02:28:54Z
establishment of protein localisation to mitochondrion
establishment of protein localization in mitochondrion
biological_process
establishment of protein localization to mitochondrion
The directed movement of a protein to the mitochondrion or a part of the mitochondrion.
GOC:mah
establishment of protein localisation to mitochondrion
GOC:mah
A process in which a protein is transported to, or maintained in, a specific location in a membrane.
midori
2011-02-14T02:35:18Z
protein localisation in membrane
protein localization in membrane
biological_process
protein localization to membrane
A process in which a protein is transported to, or maintained in, a specific location in a membrane.
GOC:mah
protein localisation in membrane
GOC:mah
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
tanyaberardini
2009-07-10T10:29:23Z
GO:0072661
GO:0090002
biological_process
protein localisation in plasma membrane
protein localization in plasma membrane
protein targeting to plasma membrane
protein-plasma membrane targeting
protein localization to plasma membrane
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
GOC:mah
protein localisation in plasma membrane
GOC:mah
protein-plasma membrane targeting
GOC:mah
A process in which a protein is transported to, or maintained at, a location in a peroxisome.
midori
2011-02-14T02:50:04Z
protein localisation to peroxisome
biological_process
protein localization to peroxisome
A process in which a protein is transported to, or maintained at, a location in a peroxisome.
GOC:ecd
protein localisation to peroxisome
GOC:mah
The directed movement of a protein to a specific location in a peroxisome.
midori
2011-02-14T02:50:36Z
establishment of protein localisation to peroxisome
biological_process
establishment of protein localization to peroxisome
The directed movement of a protein to a specific location in a peroxisome.
GOC:mah
establishment of protein localisation to peroxisome
GOC:mah
A process in which a protein is transported to, or maintained at, a location in a vacuole.
midori
2011-02-14T02:55:35Z
protein localisation to vacuole
biological_process
protein localization to vacuole
A process in which a protein is transported to, or maintained at, a location in a vacuole.
GOC:ecd
protein localisation to vacuole
GOC:mah
The directed movement of a protein to a specific location in a vacuole.
midori
2011-02-14T02:56:29Z
establishment of protein localisation to vacuole
biological_process
establishment of protein localization to vacuole
The directed movement of a protein to a specific location in a vacuole.
GOC:mah
establishment of protein localisation to vacuole
GOC:mah
A process in which a protein is transported to, or maintained in, the cell cortex.
midori
2012-04-11T01:16:33Z
protein localisation to cell cortex
biological_process
protein localization to cell cortex
A process in which a protein is transported to, or maintained in, the cell cortex.
GOC:mah
protein localisation to cell cortex
GOC:mah
A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton.
midori
2012-04-11T01:19:35Z
protein localisation to microtubule cytoskeleton
biological_process
protein localization to microtubule cytoskeleton
A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton.
GOC:mah
protein localisation to microtubule cytoskeleton
GOC:mah
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
donghui
2009-04-22T04:30:52Z
biological_process
regulation of primary metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
PMID:19211694
Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
donghui
2009-05-06T04:51:28Z
biological_process
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
regulation of response to stress
Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:dhl
Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
donghui
2009-05-06T05:02:52Z
biological_process
regulation of cellular response to stress
Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:dhl
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
donghui
2011-04-25T04:40:46Z
lytic vacuole organisation
lytic vacuolar assembly
biological_process
lytic vacuole biogenesis
lytic vacuole organization and biogenesis
lytic vacuole organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
PMID:20729380
The aggregation, arrangement and bonding together of the extracellular matrix.
jane
2010-07-14T12:52:49Z
biological_process
extracellular matrix assembly
The aggregation, arrangement and bonding together of the extracellular matrix.
GOC:jl
Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
tanyaberardini
2009-08-12T11:33:09Z
biological_process
positive regulation of microtubule nucleation
Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
GOC:dph
GOC:tb
Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
tanyaberardini
2009-09-09T11:39:52Z
biological_process
positive regulation of cell cycle process
Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
tanyaberardini
2009-09-11T10:32:17Z
biological_process
regulation of ribosome biogenesis
Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
GOC:dph
GOC:tb
Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
tanyaberardini
2009-09-11T10:32:17Z
biological_process
positive regulation of ribosome biogenesis
Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
tanyaberardini
2009-09-11T10:32:17Z
biological_process
negative regulation of ribosome biogenesis
Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
GOC:dph
GOC:tb
Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
tanyaberardini
2009-10-19T10:19:05Z
molecular_function
translation regulator activity, nucleic acid binding
Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
GOC:dph
GOC:tb
GOC:vw
Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
tanyaberardini
2009-11-04T10:03:25Z
biological_process
positive regulation of extracellular matrix disassembly
Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
tanyaberardini
2009-12-08T02:20:48Z
regulation of mitochondrial division
biological_process
regulation of mitochondrial fission
Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
GOC:ascb_2009
GOC:dph
GOC:tb
regulation of mitochondrial division
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
tanyaberardini
2009-12-08T02:20:48Z
positive regulation of mitochondrial division
biological_process
positive regulation of mitochondrial fission
Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
GOC:ascb_2009
GOC:dph
GOC:tb
positive regulation of mitochondrial division
GOC:ascb_2009
GOC:dph
GOC:tb
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined.
tanyaberardini
2009-12-08T02:35:48Z
nucleoid organisation
biological_process
nucleoid organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined.
GOC:ascb_2009
GOC:dph
GOC:tb
nucleoid organisation
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined.
tanyaberardini
2009-12-08T02:38:26Z
mitochondrial nucleoid organisation
biological_process
mitochondrial nucleoid organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined.
GOC:ascb_2009
GOC:dph
GOC:tb
mitochondrial nucleoid organisation
GOC:mah
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid that contributes to mitochondrial division.
tanyaberardini
2009-12-08T02:39:34Z
mitochondrial nucleoid organisation involved in mitochondrial fission
biological_process
mitochondrial nucleoid organization involved in mitochondrial fission
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid that contributes to mitochondrial division.
GOC:ascb_2009
GOC:dph
GOC:tb
mitochondrial nucleoid organisation involved in mitochondrial fission
GOC:ascb_2009
GOC:bf
GOC:dph
GOC:tb
The directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission.
tanyaberardini
2009-12-08T02:53:15Z
establishment of mitochondrion localisation involved in mitochondrial fission
biological_process
mitochondrial localization involved in mitochondrial fission
establishment of mitochondrion localization involved in mitochondrial fission
The directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission.
GOC:ascb_2009
GOC:dph
GOC:tb
establishment of mitochondrion localisation involved in mitochondrial fission
GOC:mah
mitochondrial localization involved in mitochondrial fission
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission.
tanyaberardini
2009-12-08T03:01:01Z
regulation of establishment of mitochondrion localisation involved in mitochondrial fission
biological_process
regulation of mitochondrial localization involved in mitochondrial fission
regulation of establishment of mitochondrion localization involved in mitochondrial fission
Any process that modulates the frequency, rate or extent of the directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission.
GOC:ascb_2009
GOC:dph
GOC:tb
regulation of establishment of mitochondrion localisation involved in mitochondrial fission
GOC:mah
regulation of mitochondrial localization involved in mitochondrial fission
GOC:dph
GOC:tb
The directed movement of a protein to a specific location in a membrane.
tanyaberardini
2009-12-08T03:18:51Z
establishment of protein localisation in membrane
establishment of protein localization in membrane
biological_process
establishment of protein localization to membrane
The directed movement of a protein to a specific location in a membrane.
GOC:ascb_2009
GOC:dph
GOC:tb
establishment of protein localisation in membrane
GOC:mah
The directed movement of substances from the Golgi to lysosomes.
tanyaberardini
2009-12-08T08:35:13Z
biological_process
Golgi to lysosome transport
The directed movement of substances from the Golgi to lysosomes.
GOC:ascb_2009
GOC:dph
GOC:tb
A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
tanyaberardini
2009-12-08T09:15:11Z
biological_process
Golgi disassembly
A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division.
tanyaberardini
2009-12-11T10:21:59Z
biological_process
regulation of Golgi inheritance
Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division.
GOC:ascb_2009
GOC:dph
GOC:tb
The joining of two lipid bilayers to form a single organelle membrane.
tanyaberardini
2009-12-11T11:44:58Z
biological_process
organelle membrane fusion
The joining of two lipid bilayers to form a single organelle membrane.
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
tanyaberardini
2010-02-03T04:05:32Z
negative regulation of mitochondrial division
biological_process
negative regulation of mitochondrial fission
Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
GOC:sl
GOC:tb
negative regulation of mitochondrial division
GOC:dph
GOC:tb
Any cellular metabolic process involving nucleic acids.
tanyaberardini
2010-04-07T10:18:47Z
biological_process
nucleic acid metabolic process
Any cellular metabolic process involving nucleic acids.
GOC:dph
GOC:tb
The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
tanyaberardini
2010-04-07T10:26:30Z
nucleic acid cleavage
biological_process
nucleic acid phosphodiester bond hydrolysis
The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
GOC:dph
GOC:tb
nucleic acid cleavage
GOC:dph
GOC:tb
Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
tanyaberardini
2010-04-16T03:42:22Z
biological_process
regulation of protein targeting to membrane
Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
GOC:tb
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
tanyaberardini
2010-04-16T03:42:22Z
biological_process
positive regulation of protein targeting to membrane
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
GOC:tb
Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
tanyaberardini
2010-04-16T03:42:22Z
biological_process
negative regulation of protein targeting to membrane
Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
GOC:tb
Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.
tanyaberardini
2010-04-16T03:45:07Z
biological_process
positive regulation of intracellular protein transport
Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.
GOC:tb
Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.
tanyaberardini
2010-04-16T03:45:07Z
biological_process
negative regulation of intracellular protein transport
Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.
GOC:tb
Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex.
tanyaberardini
2010-07-12T10:55:21Z
biological_process
regulation of proteasome assembly
Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex.
GOC:dph
GOC:elh
GOC:tb
A process in which a protein is transported to, or maintained at, a location within a nuclear envelope.
tanyaberardini
2012-07-30T01:50:41Z
protein localization in nuclear envelope
biological_process
protein localization to nuclear envelope
A process in which a protein is transported to, or maintained at, a location within a nuclear envelope.
GOC:tb
The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis.
tanyaberardini
2012-10-22T12:05:27Z
biological_process
RNA phosphodiester bond hydrolysis
The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis.
GOC:dph
GOC:tb
Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.
tanyaberardini
2014-10-24T12:43:27Z
biological_process
mitochondrial mRNA processing
Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.
GOC:tb
PMID:25181358
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion.
tanyaberardini
2015-06-12T15:57:13Z
biological_process
mitochondrial tRNA processing
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion.
GOC:vw
A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.
tanyaberardini
2016-07-19T17:00:49Z
RNA localisation to nucleus
biological_process
RNA localization to nucleus
A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.
GOC:mah
PMID:26305931
RNA localisation to nucleus
GOC:mah
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
paola
2011-03-23T01:52:31Z
cilium plasm
microtubule-based flagellar matrix
microtubule-based flagellum matrix
cellular_component
cilial cytoplasm
ciliary cytoplasm
cilium cytoplasm
microtubule-based flagellar cytoplasm
microtubule-based flagellum cytoplasm
Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term "ciliary plasm" is not linked to "cytoplasm".
ciliary plasm
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
GOC:BHF
GOC:cilia
GOC:dos
PMID:17895364
Interacting selectively and non-covalently with any part of a mitochondrial ribosome, a ribosome found in the mitochondrion of a eukaryotic cell.
paola
2011-10-11T03:03:03Z
molecular_function
mitochondrial ribosome binding
Interacting selectively and non-covalently with any part of a mitochondrial ribosome, a ribosome found in the mitochondrion of a eukaryotic cell.
GOC:ans
PMID:20739282
An arrangement of closely apposed microtubules running parallel to each other.
paola
2012-11-07T15:01:27Z
NIF_Subcellular:sao1872343973
microtubule fascicle
cellular_component
microtubule bundle
An arrangement of closely apposed microtubules running parallel to each other.
NIF_Subcellular:sao1872343973
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
paola
2012-11-27T15:46:25Z
GO:0043206
extracellular fibril organisation
extracellular fibril organization
extracellular fibril organization and biogenesis
biological_process
fibril organisation
fibril organization
supramolecular fiber organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
GOC:pr
extracellular fibril organization and biogenesis
GOC:mah
Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.
paola
2014-02-28T09:49:31Z
biological_process
vacuole fusion
Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.
GOC:pr
GOC:vw
Wikipedia:Vacuole
The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA).
paola
2014-10-01T13:49:27Z
biological_process
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
nucleic acid-templated transcription
The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA).
GOC:pr
GOC:txnOH
GOC:vw
Any vesicle that is part of the intracellular region.
paola
2016-03-29T17:39:45Z
cellular_component
intracellular vesicle
Any vesicle that is part of the intracellular region.
GOC:vesicles
The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.
paola
2016-08-05T16:12:33Z
Reactome:R-HSA-5620912.1
ciliary basal body docking
biological_process
anchoring of the basal body to the plasma membrane
Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella.
ciliary basal body-plasma membrane docking
The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.
GOC:cilia
PMID:13978319
PMID:23348840
PMID:23530209
PMID:25686250
PMID:26981235
Reactome:R-HSA-5620912.1
The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.
paola
2016-08-05T16:16:28Z
biological_process
vesicle targeting, trans-Golgi to periciliary membrane compartment
The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.
GOC:cilia
PMID:20106869
PMID:23351793
PMID:24814148
PMID:26485645
Reactome:R-HSA-5620920.1
The process of removing one or more phosphate groups from a DNA molecule.
davidos
2013-09-18T14:50:16Z
biological_process
DNA dephosphorylation
The process of removing one or more phosphate groups from a DNA molecule.
GOC:DOS
A transmembrane protein complex that functions in ATPase dependent active transport across a membrane.
davidos
2013-10-22T12:12:52Z
cellular_component
The location of this complex is implicit in its activity, so its location is asserted as a regular relationship rather than as a part of an intersection.
ATPase dependent transmembrane transport complex
A transmembrane protein complex that functions in ATPase dependent active transport across a membrane.
GOC:dos
A membrane that is a (regional) part of the plasma membrane.
davidos
2014-03-06T11:55:32Z
region of plasma membrane
cellular_component
Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.
plasma membrane region
A membrane that is a (regional) part of the plasma membrane.
GOC:dos
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell.
cell adhesion molecule
protein binding involved in cell adhesion
molecular_function
cell adhesion mediator activity
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell.
Wikipedia:Cell_adhesion
Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell.
GO:1990307
cellular_component
cell adhesion complex
protein complex involved in cell adhesion
Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell.
GOC:dos
The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.
uptake
biological_process
import into cell
The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.
GOC:dos
The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.
uptake
biological_process
import across plasma membrane
The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.
GOC:dos
A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators.
molecular_function
molecular function regulator
A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators.
GOC:dos
GOC:pt
The transcription of non (protein) coding RNA from a DNA template.
biological_process
ncRNA transcription
The transcription of non (protein) coding RNA from a DNA template.
GOC:dos
Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide.
biological_process
mRNA cleavage involved in mRNA processing
Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide.
GOC:dos
A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi apparatus.
Golgi subcompartment
cellular_component
Golgi apparatus subcompartment
A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi apparatus.
GOC:dos
Any protein complex that is part of a membrane.
cellular_component
membrane protein complex
Any protein complex that is part of a membrane.
GOC:dos
Any protein complex that is part of the plasma membrane.
cellular_component
plasma membrane protein complex
Any protein complex that is part of the plasma membrane.
GOC:dos
A protein complex that is part of a mitochondrion.
cellular_component
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
mitochondrial protein complex
A protein complex that is part of a mitochondrion.
GOC:dos
A distinct region of the endoplasmic reticulum.
cellular_component
endoplasmic reticulum subcompartment
A distinct region of the endoplasmic reticulum.
GOC:dos
The directed movement of a protein along a microtubule, mediated by motor proteins.
microtubule-based protein transport
biological_process
protein transport along microtubule
The directed movement of a protein along a microtubule, mediated by motor proteins.
PMID:25987607
The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis.
biological_process
vesicle-mediated transport to the plasma membrane
The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis.
GOC:dos
A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome.
biological_process
vesicle-mediated transport between endosomal compartments
A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome.
GOC:dos
PMID:10930469
A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.
cellular_component
supramolecular complex
A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.
GOC:dos
A polymeric supramolecular structure.
cellular_component
supramolecular polymer
A polymeric supramolecular structure.
GOC:dos
The movement of a cellular component as a result of microtubule polymerization.
biological_process
microtubule polymerization based movement
The movement of a cellular component as a result of microtubule polymerization.
GOC:cjm
ISBN:0815316194
A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
biological_process
microtubule-based transport
A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
GOC:cjm
ISBN:0815316194
The transport of a protein driven by polymerization of a microtubule to which it is attached.
biological_process
microtubule polymerization based protein transport
The transport of a protein driven by polymerization of a microtubule to which it is attached.
GOC:dos
GOC:vw
PMID:11018050
A microtubule-based process that results in the transport of proteins.
biological_process
microtubule-based protein transport
A microtubule-based process that results in the transport of proteins.
GOC:vw
Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.
biological_process
vesicle fusion to plasma membrane
Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.
GOC:aruk
GOC:bc
ISBN:0071120009
PMID:18618940
A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.
cellular_component
secretory vesicle
A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.
GOC:dos
A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
GO:0043205
cellular_component
fibril
supramolecular fiber
A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
GOC:dos
A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits.
cellular_component
polymeric cytoskeletal fiber
A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits.
GOC:dos
The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins.
cytoskeletal fiber-based vesicle localization
vesicle cytoskeletal transport
biological_process
vesicle cytoskeletal trafficking
The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins.
GOC:ecd
GOC:rl
cytoskeletal fiber-based vesicle localization
GOC:rl
Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.
cellular_component
region of cytosol
Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.
GOC:dos
Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm.
cellular_component
cytoplasmic region
Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm.
GOC:dos
The process of directing proteins towards the cell-wall.
biological_process
protein localization to cell wall
The process of directing proteins towards the cell-wall.
ISBN:0716731363
A process in which protein is transported from one region of the plasma membrane to another.
biological_process
protein transport within plasma membrane
A process in which protein is transported from one region of the plasma membrane to another.
GOC:dos
The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.
biological_process
endosome to plasma membrane protein transport
The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.
GOC:dos
The complete extent of cell cortex that underlies some some region of the plasma membrane.
perimembrane region
cellular_component
cell cortex region
The complete extent of cell cortex that underlies some some region of the plasma membrane.
GOC:dos
Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus.
hjd
2019-06-27T15:12:22Z
biological_process
regulation of vesicle fusion with Golgi apparatus
Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus.
GOC:se
PMID:26195667
Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus.
hjd
2019-06-27T15:17:17Z
biological_process
negative regulation of vesicle fusion with Golgi apparatus
Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus.
GOC:se
PMID:26195667
Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus.
hjd
2019-06-27T15:20:59Z
biological_process
positive regulation of vesicle fusion with Golgi apparatus
Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus.
GOC:se
PMID:26195667
A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane.
kmv
2018-01-29T14:46:52Z
biological_process
vesicle-mediated intercellular transport
A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane.
GOC:sp
PMID:29328915
PMID:29328916
Any process that modulates the frequency, rate, or extent of lipid transporter activity.
kmv
2018-07-06T18:53:55Z
biological_process
regulation of lipid transporter activity
Any process that modulates the frequency, rate, or extent of lipid transporter activity.
GOC:BHF
GOC:BHF_miRNA
GOC:rph
PMID:27365390
Any process that increases the frequency, rate, or extent of lipid transporter activity.
kmv
2018-07-06T19:14:13Z
biological_process
positive regulation of lipid transporter activity
Any process that increases the frequency, rate, or extent of lipid transporter activity.
GOC:BHF
GOC:BHF_miRNA
GOC:rph
PMID:27365390
Any process that decreases the frequency, rate, or extent of lipid transporter activity.
kmv
2018-07-06T19:21:44Z
biological_process
negative regulation of lipid transporter activity
Any process that decreases the frequency, rate, or extent of lipid transporter activity.
GOC:BHF
GOC:BHF_miRNA
GOC:rph
PMID:27365390
A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.
kmv
2019-08-12T18:01:37Z
cellular_component
cellular anatomical entity
A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.
GOC:kmv
A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
kchris
2017-03-21T17:26:07Z
cellular_component
plasma membrane bounded cell projection
A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
GOC:krc
Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
kchris
2017-04-24T23:56:08Z
eupodium
biological_process
plasma membrane bounded cell projection assembly
Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
GOC:krc
eupodium
GOC:krc
GOC:rjd
PMID:10328951
PMID:9096956
Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.
kchris
2017-04-26T04:27:04Z
biological_process
regulation of plasma membrane bounded cell projection assembly
Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.
GOC:krc
Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.
kchris
2017-04-26T04:34:31Z
biological_process
negative regulation of plasma membrane bounded cell projection assembly
Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.
GOC:krc
Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.
kchris
2017-04-26T04:34:45Z
biological_process
positive regulation of plasma membrane bounded cell projection assembly
Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.
GOC:krc
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.
kchris
2017-04-26T16:02:06Z
biological_process
regulation of plasma membrane bounded cell projection organization
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.
GOC:krc
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.
kchris
2017-04-26T16:07:02Z
biological_process
plasma membrane bounded cell projection organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.
GOC:krc
The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.
kchris
2017-04-28T23:39:37Z
biological_process
plasma membrane bounded cell projection morphogenesis
The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.
GOC:krc
A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
pg
2017-03-23T14:44:23Z
biological_process
mitotic nuclear division
A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
ISBN:0198547684
The cellular processes that contribute to exocytosis.
pg
2017-05-15T13:20:45Z
biological_process
exocytic process
The cellular processes that contribute to exocytosis.
Wikipedia:Exocytosis
The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
pg
2017-06-26T10:57:45Z
biological_process
mitochondrial gene expression
The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
PMID:27058308
The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other.
pg
2017-06-27T09:58:51Z
biological_process
organelle localization by membrane tethering
The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other.
PMID:27875684
Catalytic activity that acts to modify a protein.
https://github.com/geneontology/go-ontology/issues/14225
pg
2017-09-14T10:32:59Z
molecular_function
catalytic activity, acting on a protein
Catalytic activity that acts to modify a protein.
GOC:molecular_function_refactoring
GOC:pdt
Catalytic activity that acts to modify DNA.
https://github.com/geneontology/go-ontology/issues/14225
pg
2017-09-14T12:03:51Z
molecular_function
catalytic activity, acting on DNA
Catalytic activity that acts to modify DNA.
GOC:molecular_function_refactoring,GOC:pdt
A molecular function that controls the rate, timing and/or magnitude of transcription of genetic information. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism.
https://github.com/geneontology/go-ontology/issues/13588
pg
2017-10-18T07:05:44Z
molecular_function
transcription regulator activity
A molecular function that controls the rate, timing and/or magnitude of transcription of genetic information. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism.
GOC:pg
GOC:txnOH-2018
Wikipedia:Transcription_factor
The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region.
pg
2017-10-24T14:38:16Z
efflux
biological_process
export across plasma membrane
The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region.
GOC:pg
Carries substances between the nucleus and the cytoplasm of a cell by moving along with the target protein.
https://github.com/geneontology/go-ontology/issues/14336
pg
2017-12-06T13:40:40Z
GO:0061717
GO:0090631
nucleocytoplasmic importin/exportin activity
miRNA transporter activity
pre-miRNA transporter activity
molecular_function
nucleocytoplasmic carrier activity
Carries substances between the nucleus and the cytoplasm of a cell by moving along with the target protein.
GOC:pg
The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.
pg
2018-10-30T10:36:33Z
biological_process
endosome fission
The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.
PMID:25416943
PMID:30220460
Interacting selectively and non-covalently with a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.
pg
2018-11-28T12:48:20Z
molecular_function
DNA-binding transcription factor binding
Interacting selectively and non-covalently with a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.
GOC:txnOH-2018
Directly binding to a specific protein and delivering it to a specific cellular location.
https://github.com/geneontology/go-ontology/issues/17073
pg
2019-04-01T10:41:38Z
molecular_function
protein carrier activity
protein transport chaperone
Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation.
protein transporter activity
Directly binding to a specific protein and delivering it to a specific cellular location.
PMID:18706423
The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis.
pg
2019-05-22T11:20:45Z
efflux
biological_process
export from cell
The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis.
GOC:pg
The directed movement of a lipid from a cell, into the extracellular region.
pg
2019-05-22T11:33:07Z
lipid efflux
biological_process
lipid export from cell
The directed movement of a lipid from a cell, into the extracellular region.
GOC:pg
The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.
pg
2019-05-22T11:38:15Z
lipid uptake
biological_process
lipid import into cell
The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.
GOC:pg
The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation).
pg
2020-04-08T13:10:10Z
biological_process
protein targeting to Golgi apparatus
The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation).
PMID:18817523
Any process that modulates the frequency, rate or extent of protein localization to lysosome.
BarbaraCzub
2018-02-06T17:07:03Z
biological_process
regulation of protein localization to lysosome
Any process that modulates the frequency, rate or extent of protein localization to lysosome.
GOC:aruk
GOC:bc
PMID:24305806
Any process that activates or increases the frequency, rate or extent of protein localization to lysosome.
BarbaraCzub
2018-02-06T17:11:02Z
biological_process
positive regulation of protein localization to lysosome
Any process that activates or increases the frequency, rate or extent of protein localization to lysosome.
GOC:aruk
GOC:bc
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome.
BarbaraCzub
2018-02-06T17:14:16Z
biological_process
negative regulation of protein localization to lysosome
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome.
GOC:aruk
GOC:bc
PMID:24305806
The disaggregation of a cell junction into its constituent components.
BarbaraCzub
2019-12-08T11:12:13Z
biological_process
cell junction disassembly
The disaggregation of a cell junction into its constituent components.
GOC:aruk
PMID:25490267
Any process that modulates the frequency, rate or extent of peroxisome organization.
dph
2012-01-26T01:49:05Z
regulation of peroxisome organisation
biological_process
regulation of peroxisome organization and biogenesis
regulation of peroxisome-assembly ATPase activity
regulation of peroxisome organization
Any process that modulates the frequency, rate or extent of peroxisome organization.
GOC:TermGenie
PMID:7500953
regulation of peroxisome organisation
GOC:TermGenie
regulation of peroxisome organization and biogenesis
GOC:TermGenie
regulation of peroxisome-assembly ATPase activity
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of peroxisome organization.
dph
2012-01-26T01:49:09Z
positive regulation of peroxisome organisation
up regulation of peroxisome organisation
up-regulation of peroxisome organisation
upregulation of peroxisome organisation
activation of peroxisome organisation
activation of peroxisome organization
biological_process
activation of peroxisome organization and biogenesis
activation of peroxisome-assembly ATPase activity
positive regulation of peroxisome organization and biogenesis
positive regulation of peroxisome-assembly ATPase activity
up regulation of peroxisome organization
up regulation of peroxisome organization and biogenesis
up regulation of peroxisome-assembly ATPase activity
up-regulation of peroxisome organization
up-regulation of peroxisome organization and biogenesis
up-regulation of peroxisome-assembly ATPase activity
upregulation of peroxisome organization
upregulation of peroxisome organization and biogenesis
upregulation of peroxisome-assembly ATPase activity
positive regulation of peroxisome organization
Any process that activates or increases the frequency, rate or extent of peroxisome organization.
GOC:TermGenie
PMID:7500953
positive regulation of peroxisome organisation
GOC:TermGenie
up regulation of peroxisome organisation
GOC:TermGenie
up-regulation of peroxisome organisation
GOC:TermGenie
upregulation of peroxisome organisation
GOC:TermGenie
activation of peroxisome organisation
GOC:TermGenie
activation of peroxisome organization
GOC:TermGenie
activation of peroxisome organization and biogenesis
GOC:TermGenie
activation of peroxisome-assembly ATPase activity
GOC:TermGenie
positive regulation of peroxisome organization and biogenesis
GOC:TermGenie
positive regulation of peroxisome-assembly ATPase activity
GOC:TermGenie
up regulation of peroxisome organization
GOC:TermGenie
up regulation of peroxisome organization and biogenesis
GOC:TermGenie
up regulation of peroxisome-assembly ATPase activity
GOC:TermGenie
up-regulation of peroxisome organization
GOC:TermGenie
up-regulation of peroxisome organization and biogenesis
GOC:TermGenie
up-regulation of peroxisome-assembly ATPase activity
GOC:TermGenie
upregulation of peroxisome organization
GOC:TermGenie
upregulation of peroxisome organization and biogenesis
GOC:TermGenie
upregulation of peroxisome-assembly ATPase activity
GOC:TermGenie
Any regulation of signal transduction that takes place in the extracellular region.
bf
2012-02-22T10:21:48Z
regulation of signaling pathway in extracellular region
regulation of signalling pathway in extracellular region
biological_process
extracellular regulation of signal transduction
Any regulation of signal transduction that takes place in the extracellular region.
GOC:TermGenie
GOC:signaling
regulation of signaling pathway in extracellular region
GOC:TermGenie
regulation of signalling pathway in extracellular region
GOC:TermGenie
Any negative regulation of signal transduction that takes place in extracellular region.
bf
2012-02-22T10:27:56Z
down regulation of signal transduction in extracellular region
down-regulation of signal transduction in extracellular region
downregulation of signal transduction in extracellular region
negative regulation of signaling pathway in extracellular region
negative regulation of signalling pathway in extracellular region
extracellular inhibition of signaling pathway
inhibition of signal transduction in extracellular region
biological_process
extracellular negative regulation of signal transduction
Any negative regulation of signal transduction that takes place in extracellular region.
GOC:TermGenie
GOC:signaling
down regulation of signal transduction in extracellular region
GOC:TermGenie
down-regulation of signal transduction in extracellular region
GOC:TermGenie
downregulation of signal transduction in extracellular region
GOC:TermGenie
negative regulation of signaling pathway in extracellular region
GOC:TermGenie
negative regulation of signalling pathway in extracellular region
GOC:TermGenie
extracellular inhibition of signaling pathway
GOC:bf
inhibition of signal transduction in extracellular region
GOC:TermGenie
Any process that modulates the frequency, rate or extent of lipid binding.
pm
2012-02-23T04:05:03Z
biological_process
regulation of lipid binding
Any process that modulates the frequency, rate or extent of lipid binding.
GOC:TermGenie
GOC:pm
Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.
pm
2012-02-23T04:05:07Z
down regulation of lipid binding
down-regulation of lipid binding
downregulation of lipid binding
inhibition of lipid binding
biological_process
negative regulation of lipid binding
Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.
GOC:TermGenie
GOC:pm
down regulation of lipid binding
GOC:TermGenie
down-regulation of lipid binding
GOC:TermGenie
downregulation of lipid binding
GOC:TermGenie
inhibition of lipid binding
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of lipid binding.
pm
2012-02-23T04:05:11Z
up regulation of lipid binding
up-regulation of lipid binding
upregulation of lipid binding
activation of lipid binding
biological_process
positive regulation of lipid binding
Any process that activates or increases the frequency, rate or extent of lipid binding.
GOC:TermGenie
GOC:pm
up regulation of lipid binding
GOC:TermGenie
up-regulation of lipid binding
GOC:TermGenie
upregulation of lipid binding
GOC:TermGenie
activation of lipid binding
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein localization to nucleus.
bf
2012-03-12T01:23:44Z
regulation of protein localisation to nucleus
regulation of protein localization in cell nucleus
regulation of protein localization in nucleus
biological_process
regulation of protein localization to nucleus
Any process that modulates the frequency, rate or extent of protein localization to nucleus.
GOC:TermGenie
regulation of protein localisation to nucleus
GOC:TermGenie
regulation of protein localization in cell nucleus
GOC:TermGenie
regulation of protein localization in nucleus
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.
bf
2012-03-12T01:23:48Z
down regulation of protein localisation to nucleus
down regulation of protein localization in cell nucleus
down regulation of protein localization in nucleus
down regulation of protein localization to nucleus
down-regulation of protein localisation to nucleus
down-regulation of protein localization in cell nucleus
down-regulation of protein localization in nucleus
down-regulation of protein localization to nucleus
downregulation of protein localisation to nucleus
downregulation of protein localization in cell nucleus
downregulation of protein localization in nucleus
downregulation of protein localization to nucleus
negative regulation of protein localisation to nucleus
negative regulation of protein localization in cell nucleus
negative regulation of protein localization in nucleus
inhibition of protein localisation to nucleus
inhibition of protein localization in cell nucleus
inhibition of protein localization in nucleus
inhibition of protein localization to nucleus
biological_process
negative regulation of protein localization to nucleus
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.
GOC:TermGenie
down regulation of protein localisation to nucleus
GOC:TermGenie
down regulation of protein localization in cell nucleus
GOC:TermGenie
down regulation of protein localization in nucleus
GOC:TermGenie
down regulation of protein localization to nucleus
GOC:TermGenie
down-regulation of protein localisation to nucleus
GOC:TermGenie
down-regulation of protein localization in cell nucleus
GOC:TermGenie
down-regulation of protein localization in nucleus
GOC:TermGenie
down-regulation of protein localization to nucleus
GOC:TermGenie
downregulation of protein localisation to nucleus
GOC:TermGenie
downregulation of protein localization in cell nucleus
GOC:TermGenie
downregulation of protein localization in nucleus
GOC:TermGenie
downregulation of protein localization to nucleus
GOC:TermGenie
negative regulation of protein localisation to nucleus
GOC:TermGenie
negative regulation of protein localization in cell nucleus
GOC:TermGenie
negative regulation of protein localization in nucleus
GOC:TermGenie
inhibition of protein localisation to nucleus
GOC:TermGenie
inhibition of protein localization in cell nucleus
GOC:TermGenie
inhibition of protein localization in nucleus
GOC:TermGenie
inhibition of protein localization to nucleus
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
bf
2012-03-12T01:23:52Z
activation of protein localization in nucleus
positive regulation of protein localisation to nucleus
positive regulation of protein localization in cell nucleus
positive regulation of protein localization in nucleus
up regulation of protein localisation to nucleus
up regulation of protein localization in cell nucleus
up regulation of protein localization in nucleus
up regulation of protein localization to nucleus
up-regulation of protein localisation to nucleus
up-regulation of protein localization in cell nucleus
up-regulation of protein localization in nucleus
up-regulation of protein localization to nucleus
upregulation of protein localisation to nucleus
upregulation of protein localization in cell nucleus
upregulation of protein localization in nucleus
upregulation of protein localization to nucleus
activation of protein localisation to nucleus
activation of protein localization in cell nucleus
activation of protein localization to nucleus
biological_process
positive regulation of protein localization to nucleus
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
GOC:TermGenie
activation of protein localization in nucleus
GOC:TermGenie
positive regulation of protein localisation to nucleus
GOC:TermGenie
positive regulation of protein localization in cell nucleus
GOC:TermGenie
positive regulation of protein localization in nucleus
GOC:TermGenie
up regulation of protein localisation to nucleus
GOC:TermGenie
up regulation of protein localization in cell nucleus
GOC:TermGenie
up regulation of protein localization in nucleus
GOC:TermGenie
up regulation of protein localization to nucleus
GOC:TermGenie
up-regulation of protein localisation to nucleus
GOC:TermGenie
up-regulation of protein localization in cell nucleus
GOC:TermGenie
up-regulation of protein localization in nucleus
GOC:TermGenie
up-regulation of protein localization to nucleus
GOC:TermGenie
upregulation of protein localisation to nucleus
GOC:TermGenie
upregulation of protein localization in cell nucleus
GOC:TermGenie
upregulation of protein localization in nucleus
GOC:TermGenie
upregulation of protein localization to nucleus
GOC:TermGenie
activation of protein localisation to nucleus
GOC:TermGenie
activation of protein localization in cell nucleus
GOC:TermGenie
activation of protein localization to nucleus
GOC:TermGenie
Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation.
vw
2012-04-03T05:07:02Z
biological_process
regulation of cytoplasmic translational elongation
Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation.
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.
vw
2012-04-03T05:07:14Z
down regulation of cytoplasmic translational elongation
down-regulation of cytoplasmic translational elongation
downregulation of cytoplasmic translational elongation
inhibition of cytoplasmic translational elongation
biological_process
negative regulation of cytoplasmic translational elongation
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.
GOC:TermGenie
down regulation of cytoplasmic translational elongation
GOC:TermGenie
down-regulation of cytoplasmic translational elongation
GOC:TermGenie
downregulation of cytoplasmic translational elongation
GOC:TermGenie
inhibition of cytoplasmic translational elongation
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation.
vw
2012-04-03T05:07:24Z
up regulation of cytoplasmic translational elongation
up-regulation of cytoplasmic translational elongation
upregulation of cytoplasmic translational elongation
activation of cytoplasmic translational elongation
biological_process
positive regulation of cytoplasmic translational elongation
Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation.
GOC:TermGenie
up regulation of cytoplasmic translational elongation
GOC:TermGenie
up-regulation of cytoplasmic translational elongation
GOC:TermGenie
upregulation of cytoplasmic translational elongation
GOC:TermGenie
activation of cytoplasmic translational elongation
GOC:TermGenie
Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form.
bf
2012-07-16T03:29:30Z
expression of extracellular matrix proteins
biological_process
extracellular matrix protein production
gene expression involved in extracellular matrix organization
Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form.
GOC:TermGenie
GOC:pg
PMID:18668558
expression of extracellular matrix proteins
GOC:bf
extracellular matrix protein production
GOC:pg
Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex.
ss
2012-07-25T02:26:58Z
regulation of translation initiation ternary complex assembly
biological_process
regulation of formation of translation initiation ternary complex
Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex.
GOC:TermGenie
regulation of translation initiation ternary complex assembly
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex.
ss
2012-07-25T02:27:21Z
down regulation of formation of translation initiation ternary complex
down regulation of translation initiation ternary complex assembly
down-regulation of formation of translation initiation ternary complex
down-regulation of translation initiation ternary complex assembly
downregulation of formation of translation initiation ternary complex
downregulation of translation initiation ternary complex assembly
inhibition of translation initiation ternary complex assembly
negative regulation of translation initiation ternary complex assembly
inhibition of formation of translation initiation ternary complex
biological_process
negative regulation of formation of translation initiation ternary complex
Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex.
GOC:TermGenie
down regulation of formation of translation initiation ternary complex
GOC:TermGenie
down regulation of translation initiation ternary complex assembly
GOC:TermGenie
down-regulation of formation of translation initiation ternary complex
GOC:TermGenie
down-regulation of translation initiation ternary complex assembly
GOC:TermGenie
downregulation of formation of translation initiation ternary complex
GOC:TermGenie
downregulation of translation initiation ternary complex assembly
GOC:TermGenie
inhibition of translation initiation ternary complex assembly
GOC:TermGenie
negative regulation of translation initiation ternary complex assembly
GOC:TermGenie
inhibition of formation of translation initiation ternary complex
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex.
ss
2012-07-25T02:27:29Z
activation of translation initiation ternary complex assembly
positive regulation of translation initiation ternary complex assembly
up regulation of formation of translation initiation ternary complex
up regulation of translation initiation ternary complex assembly
up-regulation of formation of translation initiation ternary complex
up-regulation of translation initiation ternary complex assembly
upregulation of formation of translation initiation ternary complex
upregulation of translation initiation ternary complex assembly
activation of formation of translation initiation ternary complex
biological_process
positive regulation of formation of translation initiation ternary complex
Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex.
GOC:TermGenie
activation of translation initiation ternary complex assembly
GOC:TermGenie
positive regulation of translation initiation ternary complex assembly
GOC:TermGenie
up regulation of formation of translation initiation ternary complex
GOC:TermGenie
up regulation of translation initiation ternary complex assembly
GOC:TermGenie
up-regulation of formation of translation initiation ternary complex
GOC:TermGenie
up-regulation of translation initiation ternary complex assembly
GOC:TermGenie
upregulation of formation of translation initiation ternary complex
GOC:TermGenie
upregulation of translation initiation ternary complex assembly
GOC:TermGenie
activation of formation of translation initiation ternary complex
GOC:TermGenie
Any process that modulates the frequency, rate or extent of extracellular matrix assembly.
rl
2012-07-27T04:04:00Z
biological_process
regulation of extracellular matrix assembly
Any process that modulates the frequency, rate or extent of extracellular matrix assembly.
GOC:BHF
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.
rl
2012-07-27T04:04:24Z
down regulation of extracellular matrix assembly
down-regulation of extracellular matrix assembly
downregulation of extracellular matrix assembly
inhibition of extracellular matrix assembly
biological_process
negative regulation of extracellular matrix assembly
Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.
GOC:BHF
GOC:TermGenie
down regulation of extracellular matrix assembly
GOC:TermGenie
down-regulation of extracellular matrix assembly
GOC:TermGenie
downregulation of extracellular matrix assembly
GOC:TermGenie
inhibition of extracellular matrix assembly
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.
rl
2012-07-27T04:04:32Z
up regulation of extracellular matrix assembly
up-regulation of extracellular matrix assembly
upregulation of extracellular matrix assembly
activation of extracellular matrix assembly
biological_process
positive regulation of extracellular matrix assembly
Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.
GOC:BHF
GOC:TermGenie
up regulation of extracellular matrix assembly
GOC:TermGenie
up-regulation of extracellular matrix assembly
GOC:TermGenie
upregulation of extracellular matrix assembly
GOC:TermGenie
activation of extracellular matrix assembly
GOC:TermGenie
The chemical reactions and pathways involving organonitrogen compound.
pr
2012-11-04T15:17:52Z
organonitrogen compound metabolism
biological_process
organonitrogen compound metabolic process
The chemical reactions and pathways involving organonitrogen compound.
GOC:TermGenie
GOC:pr
organonitrogen compound metabolism
GOC:TermGenie
The chemical reactions and pathways resulting in the breakdown of organonitrogen compound.
pr
2012-11-04T15:17:56Z
organonitrogen compound breakdown
organonitrogen compound catabolism
organonitrogen compound degradation
biological_process
organonitrogen compound catabolic process
The chemical reactions and pathways resulting in the breakdown of organonitrogen compound.
GOC:TermGenie
GOC:pr
organonitrogen compound breakdown
GOC:TermGenie
organonitrogen compound catabolism
GOC:TermGenie
organonitrogen compound degradation
GOC:TermGenie
The chemical reactions and pathways resulting in the formation of organonitrogen compound.
pr
2012-11-04T15:18:00Z
organonitrogen compound anabolism
organonitrogen compound biosynthesis
organonitrogen compound formation
organonitrogen compound synthesis
biological_process
organonitrogen compound biosynthetic process
The chemical reactions and pathways resulting in the formation of organonitrogen compound.
GOC:TermGenie
GOC:pr
organonitrogen compound anabolism
GOC:TermGenie
organonitrogen compound biosynthesis
GOC:TermGenie
organonitrogen compound formation
GOC:TermGenie
organonitrogen compound synthesis
GOC:TermGenie
The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon.
pr
2012-11-05T11:04:36Z
organic molecular entity breakdown
organic molecular entity catabolic process
organic molecular entity catabolism
organic molecular entity degradation
organic substance breakdown
organic substance catabolism
organic substance degradation
biological_process
organic substance catabolic process
The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon.
GOC:TermGenie
GOC:pr
organic molecular entity breakdown
GOC:TermGenie
organic molecular entity catabolism
GOC:TermGenie
organic molecular entity degradation
GOC:TermGenie
The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
pr
2012-11-05T11:04:40Z
organic molecular entity anabolism
organic molecular entity biosynthesis
organic molecular entity biosynthetic process
organic molecular entity formation
organic molecular entity synthesis
organic substance anabolism
organic substance biosynthesis
organic substance formation
organic substance synthesis
biological_process
organic substance biosynthetic process
The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
GOC:TermGenie
GOC:pr
organic molecular entity anabolism
GOC:TermGenie
organic molecular entity biosynthesis
GOC:TermGenie
organic molecular entity formation
GOC:TermGenie
organic molecular entity synthesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of vesicle transport along microtubule.
hjd
2012-11-08T21:49:44Z
regulation of microtubule-based vesicle localization
biological_process
regulation of vesicle transport along microtubule
Any process that modulates the frequency, rate or extent of vesicle transport along microtubule.
GOC:TermGenie
regulation of microtubule-based vesicle localization
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.
hjd
2012-11-08T21:49:48Z
down regulation of microtubule-based vesicle localization
down regulation of vesicle transport along microtubule
down-regulation of microtubule-based vesicle localization
down-regulation of vesicle transport along microtubule
downregulation of microtubule-based vesicle localization
downregulation of vesicle transport along microtubule
inhibition of microtubule-based vesicle localization
negative regulation of microtubule-based vesicle localization
inhibition of vesicle transport along microtubule
biological_process
negative regulation of vesicle transport along microtubule
Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.
GOC:TermGenie
down regulation of microtubule-based vesicle localization
GOC:TermGenie
down regulation of vesicle transport along microtubule
GOC:TermGenie
down-regulation of microtubule-based vesicle localization
GOC:TermGenie
down-regulation of vesicle transport along microtubule
GOC:TermGenie
downregulation of microtubule-based vesicle localization
GOC:TermGenie
downregulation of vesicle transport along microtubule
GOC:TermGenie
inhibition of microtubule-based vesicle localization
GOC:TermGenie
negative regulation of microtubule-based vesicle localization
GOC:TermGenie
inhibition of vesicle transport along microtubule
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule.
hjd
2012-11-08T21:49:53Z
activation of microtubule-based vesicle localization
positive regulation of microtubule-based vesicle localization
up regulation of microtubule-based vesicle localization
up regulation of vesicle transport along microtubule
up-regulation of microtubule-based vesicle localization
up-regulation of vesicle transport along microtubule
upregulation of microtubule-based vesicle localization
upregulation of vesicle transport along microtubule
activation of vesicle transport along microtubule
biological_process
positive regulation of vesicle transport along microtubule
Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule.
GOC:TermGenie
activation of microtubule-based vesicle localization
GOC:TermGenie
positive regulation of microtubule-based vesicle localization
GOC:TermGenie
up regulation of microtubule-based vesicle localization
GOC:TermGenie
up regulation of vesicle transport along microtubule
GOC:TermGenie
up-regulation of microtubule-based vesicle localization
GOC:TermGenie
up-regulation of vesicle transport along microtubule
GOC:TermGenie
upregulation of microtubule-based vesicle localization
GOC:TermGenie
upregulation of vesicle transport along microtubule
GOC:TermGenie
activation of vesicle transport along microtubule
GOC:TermGenie
A response that results in a state of tolerance to ketone.
pr
2012-11-20T10:55:47Z
GO:1990369
process resulting in tolerance to ketone
biological_process
response to ketone
A response that results in a state of tolerance to ketone.
GOC:mengo_curators
PMID:23356676
Interacting selectively and non-covalently with a sulfur compound.
pr
2012-11-26T20:45:23Z
sulfur molecular entity binding
molecular_function
sulfur compound binding
Interacting selectively and non-covalently with a sulfur compound.
GOC:TermGenie
GOC:pr
Enables the transfer of a sulfur compound from one side of a membrane to the other.
pr
2012-11-26T20:45:29Z
sulfur molecular entity transmembrane transporter activity
molecular_function
sulfur compound transmembrane transporter activity
Enables the transfer of a sulfur compound from one side of a membrane to the other.
GOC:TermGenie
GOC:pr
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.
pr
2012-12-13T15:06:08Z
response to nitrogen molecular entity
biological_process
response to nitrogen compound
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.
GOC:TermGenie
GOC:pr
Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.
rl
2013-01-21T20:10:54Z
down regulation of proteasomal protein catabolic process
down regulation of proteasome-mediated protein catabolic process
down regulation of proteasome-mediated protein catabolism
down-regulation of proteasomal protein catabolic process
down-regulation of proteasome-mediated protein catabolic process
down-regulation of proteasome-mediated protein catabolism
downregulation of proteasomal protein catabolic process
downregulation of proteasome-mediated protein catabolic process
downregulation of proteasome-mediated protein catabolism
inhibition of proteasome-mediated protein catabolic process
inhibition of proteasome-mediated protein catabolism
negative regulation of proteasome-mediated protein catabolic process
negative regulation of proteasome-mediated protein catabolism
inhibition of proteasomal protein catabolic process
biological_process
negative regulation of proteasomal protein catabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.
GOC:BHF
GOC:TermGenie
GOC:rl
PMID:21669198
down regulation of proteasomal protein catabolic process
GOC:TermGenie
down regulation of proteasome-mediated protein catabolic process
GOC:TermGenie
down regulation of proteasome-mediated protein catabolism
GOC:TermGenie
down-regulation of proteasomal protein catabolic process
GOC:TermGenie
down-regulation of proteasome-mediated protein catabolic process
GOC:TermGenie
down-regulation of proteasome-mediated protein catabolism
GOC:TermGenie
downregulation of proteasomal protein catabolic process
GOC:TermGenie
downregulation of proteasome-mediated protein catabolic process
GOC:TermGenie
downregulation of proteasome-mediated protein catabolism
GOC:TermGenie
inhibition of proteasome-mediated protein catabolic process
GOC:TermGenie
inhibition of proteasome-mediated protein catabolism
GOC:TermGenie
negative regulation of proteasome-mediated protein catabolic process
GOC:TermGenie
negative regulation of proteasome-mediated protein catabolism
GOC:TermGenie
inhibition of proteasomal protein catabolic process
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process.
rl
2013-01-21T20:10:58Z
activation of proteasome-mediated protein catabolic process
activation of proteasome-mediated protein catabolism
positive regulation of proteasome-mediated protein catabolic process
positive regulation of proteasome-mediated protein catabolism
up regulation of proteasomal protein catabolic process
up regulation of proteasome-mediated protein catabolic process
up regulation of proteasome-mediated protein catabolism
up-regulation of proteasomal protein catabolic process
up-regulation of proteasome-mediated protein catabolic process
up-regulation of proteasome-mediated protein catabolism
upregulation of proteasomal protein catabolic process
upregulation of proteasome-mediated protein catabolic process
upregulation of proteasome-mediated protein catabolism
activation of proteasomal protein catabolic process
biological_process
positive regulation of proteasomal protein catabolic process
Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process.
GOC:BHF
GOC:TermGenie
GOC:rl
PMID:21669198
activation of proteasome-mediated protein catabolic process
GOC:TermGenie
activation of proteasome-mediated protein catabolism
GOC:TermGenie
positive regulation of proteasome-mediated protein catabolic process
GOC:TermGenie
positive regulation of proteasome-mediated protein catabolism
GOC:TermGenie
up regulation of proteasomal protein catabolic process
GOC:TermGenie
up regulation of proteasome-mediated protein catabolic process
GOC:TermGenie
up regulation of proteasome-mediated protein catabolism
GOC:TermGenie
up-regulation of proteasomal protein catabolic process
GOC:TermGenie
up-regulation of proteasome-mediated protein catabolic process
GOC:TermGenie
up-regulation of proteasome-mediated protein catabolism
GOC:TermGenie
upregulation of proteasomal protein catabolic process
GOC:TermGenie
upregulation of proteasome-mediated protein catabolic process
GOC:TermGenie
upregulation of proteasome-mediated protein catabolism
GOC:TermGenie
activation of proteasomal protein catabolic process
GOC:TermGenie
Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.
yaf
2013-02-01T10:05:04Z
regulation of mitochondrial DNA metabolism
regulation of mtDNA metabolic process
regulation of mtDNA metabolism
biological_process
regulation of mitochondrial DNA metabolic process
Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.
GOC:TermGenie
GOC:yaf
PMID:23150719
regulation of mitochondrial DNA metabolism
GOC:TermGenie
regulation of mtDNA metabolic process
GOC:TermGenie
regulation of mtDNA metabolism
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.
yaf
2013-02-01T10:05:09Z
down regulation of mitochondrial DNA metabolic process
down regulation of mitochondrial DNA metabolism
down regulation of mtDNA metabolic process
down regulation of mtDNA metabolism
down-regulation of mitochondrial DNA metabolic process
down-regulation of mitochondrial DNA metabolism
down-regulation of mtDNA metabolic process
down-regulation of mtDNA metabolism
downregulation of mitochondrial DNA metabolic process
downregulation of mitochondrial DNA metabolism
downregulation of mtDNA metabolic process
downregulation of mtDNA metabolism
inhibition of mitochondrial DNA metabolism
inhibition of mtDNA metabolic process
inhibition of mtDNA metabolism
negative regulation of mitochondrial DNA metabolism
negative regulation of mtDNA metabolic process
negative regulation of mtDNA metabolism
inhibition of mitochondrial DNA metabolic process
biological_process
negative regulation of mitochondrial DNA metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.
GOC:TermGenie
GOC:yaf
PMID:23150719
down regulation of mitochondrial DNA metabolic process
GOC:TermGenie
down regulation of mitochondrial DNA metabolism
GOC:TermGenie
down regulation of mtDNA metabolic process
GOC:TermGenie
down regulation of mtDNA metabolism
GOC:TermGenie
down-regulation of mitochondrial DNA metabolic process
GOC:TermGenie
down-regulation of mitochondrial DNA metabolism
GOC:TermGenie
down-regulation of mtDNA metabolic process
GOC:TermGenie
down-regulation of mtDNA metabolism
GOC:TermGenie
downregulation of mitochondrial DNA metabolic process
GOC:TermGenie
downregulation of mitochondrial DNA metabolism
GOC:TermGenie
downregulation of mtDNA metabolic process
GOC:TermGenie
downregulation of mtDNA metabolism
GOC:TermGenie
inhibition of mitochondrial DNA metabolism
GOC:TermGenie
inhibition of mtDNA metabolic process
GOC:TermGenie
inhibition of mtDNA metabolism
GOC:TermGenie
negative regulation of mitochondrial DNA metabolism
GOC:TermGenie
negative regulation of mtDNA metabolic process
GOC:TermGenie
negative regulation of mtDNA metabolism
GOC:TermGenie
inhibition of mitochondrial DNA metabolic process
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.
yaf
2013-02-01T10:05:14Z
activation of mitochondrial DNA metabolism
activation of mtDNA metabolic process
activation of mtDNA metabolism
positive regulation of mitochondrial DNA metabolism
positive regulation of mtDNA metabolic process
positive regulation of mtDNA metabolism
up regulation of mitochondrial DNA metabolic process
up regulation of mitochondrial DNA metabolism
up regulation of mtDNA metabolic process
up regulation of mtDNA metabolism
up-regulation of mitochondrial DNA metabolic process
up-regulation of mitochondrial DNA metabolism
up-regulation of mtDNA metabolic process
up-regulation of mtDNA metabolism
upregulation of mitochondrial DNA metabolic process
upregulation of mitochondrial DNA metabolism
upregulation of mtDNA metabolic process
upregulation of mtDNA metabolism
activation of mitochondrial DNA metabolic process
biological_process
positive regulation of mitochondrial DNA metabolic process
Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.
GOC:TermGenie
GOC:yaf
PMID:23150719
activation of mitochondrial DNA metabolism
GOC:TermGenie
activation of mtDNA metabolic process
GOC:TermGenie
activation of mtDNA metabolism
GOC:TermGenie
positive regulation of mitochondrial DNA metabolism
GOC:TermGenie
positive regulation of mtDNA metabolic process
GOC:TermGenie
positive regulation of mtDNA metabolism
GOC:TermGenie
up regulation of mitochondrial DNA metabolic process
GOC:TermGenie
up regulation of mitochondrial DNA metabolism
GOC:TermGenie
up regulation of mtDNA metabolic process
GOC:TermGenie
up regulation of mtDNA metabolism
GOC:TermGenie
up-regulation of mitochondrial DNA metabolic process
GOC:TermGenie
up-regulation of mitochondrial DNA metabolism
GOC:TermGenie
up-regulation of mtDNA metabolic process
GOC:TermGenie
up-regulation of mtDNA metabolism
GOC:TermGenie
upregulation of mitochondrial DNA metabolic process
GOC:TermGenie
upregulation of mitochondrial DNA metabolism
GOC:TermGenie
upregulation of mtDNA metabolic process
GOC:TermGenie
upregulation of mtDNA metabolism
GOC:TermGenie
activation of mitochondrial DNA metabolic process
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein depolymerization.
rl
2013-02-06T13:57:23Z
regulation of protein polymer breakdown
regulation of protein polymer catabolic process
regulation of protein polymer catabolism
regulation of protein polymer degradation
biological_process
regulation of protein depolymerization
Any process that modulates the frequency, rate or extent of protein depolymerization.
GOC:BHF
GOC:TermGenie
GOC:rl
PMID:12032137
regulation of protein polymer breakdown
GOC:TermGenie
regulation of protein polymer catabolic process
GOC:TermGenie
regulation of protein polymer catabolism
GOC:TermGenie
regulation of protein polymer degradation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.
rl
2013-02-06T13:57:28Z
down regulation of protein depolymerization
down regulation of protein polymer breakdown
down regulation of protein polymer catabolic process
down regulation of protein polymer catabolism
down regulation of protein polymer degradation
down-regulation of protein depolymerization
down-regulation of protein polymer breakdown
down-regulation of protein polymer catabolic process
down-regulation of protein polymer catabolism
down-regulation of protein polymer degradation
downregulation of protein depolymerization
downregulation of protein polymer breakdown
downregulation of protein polymer catabolic process
downregulation of protein polymer catabolism
downregulation of protein polymer degradation
inhibition of protein polymer breakdown
inhibition of protein polymer catabolic process
inhibition of protein polymer catabolism
inhibition of protein polymer degradation
negative regulation of protein polymer breakdown
negative regulation of protein polymer catabolic process
negative regulation of protein polymer catabolism
negative regulation of protein polymer degradation
inhibition of protein depolymerization
biological_process
negative regulation of protein depolymerization
Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.
GOC:BHF
GOC:TermGenie
GOC:rl
PMID:12032137
down regulation of protein depolymerization
GOC:TermGenie
down regulation of protein polymer breakdown
GOC:TermGenie
down regulation of protein polymer catabolic process
GOC:TermGenie
down regulation of protein polymer catabolism
GOC:TermGenie
down regulation of protein polymer degradation
GOC:TermGenie
down-regulation of protein depolymerization
GOC:TermGenie
down-regulation of protein polymer breakdown
GOC:TermGenie
down-regulation of protein polymer catabolic process
GOC:TermGenie
down-regulation of protein polymer catabolism
GOC:TermGenie
down-regulation of protein polymer degradation
GOC:TermGenie
downregulation of protein depolymerization
GOC:TermGenie
downregulation of protein polymer breakdown
GOC:TermGenie
downregulation of protein polymer catabolic process
GOC:TermGenie
downregulation of protein polymer catabolism
GOC:TermGenie
downregulation of protein polymer degradation
GOC:TermGenie
inhibition of protein polymer breakdown
GOC:TermGenie
inhibition of protein polymer catabolic process
GOC:TermGenie
inhibition of protein polymer catabolism
GOC:TermGenie
inhibition of protein polymer degradation
GOC:TermGenie
negative regulation of protein polymer breakdown
GOC:TermGenie
negative regulation of protein polymer catabolic process
GOC:TermGenie
negative regulation of protein polymer catabolism
GOC:TermGenie
negative regulation of protein polymer degradation
GOC:TermGenie
inhibition of protein depolymerization
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein depolymerization.
rl
2013-02-06T13:57:32Z
activation of protein polymer breakdown
activation of protein polymer catabolic process
activation of protein polymer catabolism
activation of protein polymer degradation
positive regulation of protein polymer breakdown
positive regulation of protein polymer catabolic process
positive regulation of protein polymer catabolism
positive regulation of protein polymer degradation
up regulation of protein depolymerization
up regulation of protein polymer breakdown
up regulation of protein polymer catabolic process
up regulation of protein polymer catabolism
up regulation of protein polymer degradation
up-regulation of protein depolymerization
up-regulation of protein polymer breakdown
up-regulation of protein polymer catabolic process
up-regulation of protein polymer catabolism
up-regulation of protein polymer degradation
upregulation of protein depolymerization
upregulation of protein polymer breakdown
upregulation of protein polymer catabolic process
upregulation of protein polymer catabolism
upregulation of protein polymer degradation
activation of protein depolymerization
biological_process
positive regulation of protein depolymerization
Any process that activates or increases the frequency, rate or extent of protein depolymerization.
GOC:BHF
GOC:TermGenie
GOC:rl
PMID:12032137
activation of protein polymer breakdown
GOC:TermGenie
activation of protein polymer catabolic process
GOC:TermGenie
activation of protein polymer catabolism
GOC:TermGenie
activation of protein polymer degradation
GOC:TermGenie
positive regulation of protein polymer breakdown
GOC:TermGenie
positive regulation of protein polymer catabolic process
GOC:TermGenie
positive regulation of protein polymer catabolism
GOC:TermGenie
positive regulation of protein polymer degradation
GOC:TermGenie
up regulation of protein depolymerization
GOC:TermGenie
up regulation of protein polymer breakdown
GOC:TermGenie
up regulation of protein polymer catabolic process
GOC:TermGenie
up regulation of protein polymer catabolism
GOC:TermGenie
up regulation of protein polymer degradation
GOC:TermGenie
up-regulation of protein depolymerization
GOC:TermGenie
up-regulation of protein polymer breakdown
GOC:TermGenie
up-regulation of protein polymer catabolic process
GOC:TermGenie
up-regulation of protein polymer catabolism
GOC:TermGenie
up-regulation of protein polymer degradation
GOC:TermGenie
upregulation of protein depolymerization
GOC:TermGenie
upregulation of protein polymer breakdown
GOC:TermGenie
upregulation of protein polymer catabolic process
GOC:TermGenie
upregulation of protein polymer catabolism
GOC:TermGenie
upregulation of protein polymer degradation
GOC:TermGenie
activation of protein depolymerization
GOC:TermGenie
Any process that modulates the frequency, rate or extent of cell junction assembly.
tb
2013-02-06T19:40:32Z
biological_process
regulation of cell junction assembly
Any process that modulates the frequency, rate or extent of cell junction assembly.
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly.
tb
2013-02-06T19:40:41Z
down regulation of cell junction assembly
down-regulation of cell junction assembly
downregulation of cell junction assembly
inhibition of cell junction assembly
biological_process
negative regulation of cell junction assembly
Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly.
GOC:TermGenie
down regulation of cell junction assembly
GOC:TermGenie
down-regulation of cell junction assembly
GOC:TermGenie
downregulation of cell junction assembly
GOC:TermGenie
inhibition of cell junction assembly
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of cell junction assembly.
tb
2013-02-06T19:40:46Z
up regulation of cell junction assembly
up-regulation of cell junction assembly
upregulation of cell junction assembly
activation of cell junction assembly
biological_process
positive regulation of cell junction assembly
Any process that activates or increases the frequency, rate or extent of cell junction assembly.
GOC:TermGenie
up regulation of cell junction assembly
GOC:TermGenie
up-regulation of cell junction assembly
GOC:TermGenie
upregulation of cell junction assembly
GOC:TermGenie
activation of cell junction assembly
GOC:TermGenie
Any process that modulates the frequency, rate or extent of cilium assembly.
dph
2013-03-26T18:10:51Z
regulation of ciliogenesis
biological_process
regulation of cilium biogenesis
regulation of cilium assembly
Any process that modulates the frequency, rate or extent of cilium assembly.
GOC:TermGenie
GOC:cilia
GOC:dph
PMID:17719545
regulation of ciliogenesis
GOC:TermGenie
regulation of cilium biogenesis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.
dph
2013-03-26T18:10:56Z
down regulation of ciliogenesis
down regulation of cilium assembly
down-regulation of ciliogenesis
down-regulation of cilium assembly
downregulation of ciliogenesis
downregulation of cilium assembly
inhibition of ciliogenesis
negative regulation of ciliogenesis
inhibition of cilium assembly
biological_process
down regulation of cilium biogenesis
down-regulation of cilium biogenesis
downregulation of cilium biogenesis
inhibition of cilium biogenesis
negative regulation of cilium biogenesis
negative regulation of cilium assembly
Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.
GOC:TermGenie
GOC:cilia
GOC:dph
PMID:17719545
down regulation of ciliogenesis
GOC:TermGenie
down regulation of cilium assembly
GOC:TermGenie
down-regulation of ciliogenesis
GOC:TermGenie
down-regulation of cilium assembly
GOC:TermGenie
downregulation of ciliogenesis
GOC:TermGenie
downregulation of cilium assembly
GOC:TermGenie
inhibition of ciliogenesis
GOC:TermGenie
negative regulation of ciliogenesis
GOC:TermGenie
inhibition of cilium assembly
GOC:TermGenie
down regulation of cilium biogenesis
GOC:TermGenie
down-regulation of cilium biogenesis
GOC:TermGenie
downregulation of cilium biogenesis
GOC:TermGenie
inhibition of cilium biogenesis
GOC:TermGenie
negative regulation of cilium biogenesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of organelle assembly.
pr
2013-05-14T09:43:21Z
biological_process
regulation of organelle assembly
Any process that modulates the frequency, rate or extent of organelle assembly.
GOC:TermGenie
GOC:pr
Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.
pr
2013-05-14T09:43:31Z
down regulation of organelle assembly
down-regulation of organelle assembly
downregulation of organelle assembly
inhibition of organelle assembly
biological_process
negative regulation of organelle assembly
Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.
GOC:TermGenie
GOC:pr
down regulation of organelle assembly
GOC:TermGenie
down-regulation of organelle assembly
GOC:TermGenie
downregulation of organelle assembly
GOC:TermGenie
inhibition of organelle assembly
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of organelle assembly.
pr
2013-05-14T09:43:36Z
up regulation of organelle assembly
up-regulation of organelle assembly
upregulation of organelle assembly
activation of organelle assembly
biological_process
positive regulation of organelle assembly
Any process that activates or increases the frequency, rate or extent of organelle assembly.
GOC:TermGenie
GOC:pr
up regulation of organelle assembly
GOC:TermGenie
up-regulation of organelle assembly
GOC:TermGenie
upregulation of organelle assembly
GOC:TermGenie
activation of organelle assembly
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process.
bf
2013-08-22T14:59:39Z
down regulation of RNA breakdown
down regulation of RNA catabolic process
down regulation of RNA catabolism
down regulation of RNA degradation
down-regulation of RNA breakdown
down-regulation of RNA catabolic process
down-regulation of RNA catabolism
down-regulation of RNA degradation
downregulation of RNA breakdown
downregulation of RNA catabolic process
downregulation of RNA catabolism
downregulation of RNA degradation
negative regulation of RNA breakdown
negative regulation of RNA catabolism
negative regulation of RNA degradation
inhibition of RNA breakdown
inhibition of RNA catabolic process
inhibition of RNA catabolism
inhibition of RNA degradation
biological_process
negative regulation of RNA catabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process.
GOC:TermGenie
GOC:bf
PMID:16640457
down regulation of RNA breakdown
GOC:TermGenie
down regulation of RNA catabolic process
GOC:TermGenie
down regulation of RNA catabolism
GOC:TermGenie
down regulation of RNA degradation
GOC:TermGenie
down-regulation of RNA breakdown
GOC:TermGenie
down-regulation of RNA catabolic process
GOC:TermGenie
down-regulation of RNA catabolism
GOC:TermGenie
down-regulation of RNA degradation
GOC:TermGenie
downregulation of RNA breakdown
GOC:TermGenie
downregulation of RNA catabolic process
GOC:TermGenie
downregulation of RNA catabolism
GOC:TermGenie
downregulation of RNA degradation
GOC:TermGenie
negative regulation of RNA breakdown
GOC:TermGenie
negative regulation of RNA catabolism
GOC:TermGenie
negative regulation of RNA degradation
GOC:TermGenie
inhibition of RNA breakdown
GOC:TermGenie
inhibition of RNA catabolic process
GOC:TermGenie
inhibition of RNA catabolism
GOC:TermGenie
inhibition of RNA degradation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of tRNA catabolic process.
bf
2013-08-22T15:08:12Z
regulation of tRNA breakdown
regulation of tRNA catabolism
regulation of tRNA degradation
biological_process
regulation of tRNA catabolic process
Any process that modulates the frequency, rate or extent of tRNA catabolic process.
GOC:TermGenie
GOC:bf
regulation of tRNA breakdown
GOC:TermGenie
regulation of tRNA catabolism
GOC:TermGenie
regulation of tRNA degradation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process.
bf
2013-08-22T15:08:20Z
down regulation of tRNA breakdown
down regulation of tRNA catabolic process
down regulation of tRNA catabolism
down regulation of tRNA degradation
down-regulation of tRNA breakdown
down-regulation of tRNA catabolic process
down-regulation of tRNA catabolism
down-regulation of tRNA degradation
downregulation of tRNA breakdown
downregulation of tRNA catabolic process
downregulation of tRNA catabolism
downregulation of tRNA degradation
negative regulation of tRNA breakdown
negative regulation of tRNA catabolism
negative regulation of tRNA degradation
inhibition of tRNA breakdown
inhibition of tRNA catabolic process
inhibition of tRNA catabolism
inhibition of tRNA degradation
biological_process
negative regulation of tRNA catabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process.
GOC:TermGenie
GOC:bf
PMID:22919049
down regulation of tRNA breakdown
GOC:TermGenie
down regulation of tRNA catabolic process
GOC:TermGenie
down regulation of tRNA catabolism
GOC:TermGenie
down regulation of tRNA degradation
GOC:TermGenie
down-regulation of tRNA breakdown
GOC:TermGenie
down-regulation of tRNA catabolic process
GOC:TermGenie
down-regulation of tRNA catabolism
GOC:TermGenie
down-regulation of tRNA degradation
GOC:TermGenie
downregulation of tRNA breakdown
GOC:TermGenie
downregulation of tRNA catabolic process
GOC:TermGenie
downregulation of tRNA catabolism
GOC:TermGenie
downregulation of tRNA degradation
GOC:TermGenie
negative regulation of tRNA breakdown
GOC:TermGenie
negative regulation of tRNA catabolism
GOC:TermGenie
negative regulation of tRNA degradation
GOC:TermGenie
inhibition of tRNA breakdown
GOC:TermGenie
inhibition of tRNA catabolic process
GOC:TermGenie
inhibition of tRNA catabolism
GOC:TermGenie
inhibition of tRNA degradation
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of tRNA catabolic process.
bf
2013-08-22T15:08:29Z
positive regulation of tRNA breakdown
positive regulation of tRNA catabolism
positive regulation of tRNA degradation
up regulation of tRNA breakdown
up regulation of tRNA catabolic process
up regulation of tRNA catabolism
up regulation of tRNA degradation
up-regulation of tRNA breakdown
up-regulation of tRNA catabolic process
up-regulation of tRNA catabolism
up-regulation of tRNA degradation
upregulation of tRNA breakdown
upregulation of tRNA catabolic process
upregulation of tRNA catabolism
upregulation of tRNA degradation
activation of tRNA breakdown
activation of tRNA catabolic process
activation of tRNA catabolism
activation of tRNA degradation
biological_process
positive regulation of tRNA catabolic process
Any process that activates or increases the frequency, rate or extent of tRNA catabolic process.
GOC:TermGenie
GOC:bf
positive regulation of tRNA breakdown
GOC:TermGenie
positive regulation of tRNA catabolism
GOC:TermGenie
positive regulation of tRNA degradation
GOC:TermGenie
up regulation of tRNA breakdown
GOC:TermGenie
up regulation of tRNA catabolic process
GOC:TermGenie
up regulation of tRNA catabolism
GOC:TermGenie
up regulation of tRNA degradation
GOC:TermGenie
up-regulation of tRNA breakdown
GOC:TermGenie
up-regulation of tRNA catabolic process
GOC:TermGenie
up-regulation of tRNA catabolism
GOC:TermGenie
up-regulation of tRNA degradation
GOC:TermGenie
upregulation of tRNA breakdown
GOC:TermGenie
upregulation of tRNA catabolic process
GOC:TermGenie
upregulation of tRNA catabolism
GOC:TermGenie
upregulation of tRNA degradation
GOC:TermGenie
activation of tRNA breakdown
GOC:TermGenie
activation of tRNA catabolic process
GOC:TermGenie
activation of tRNA catabolism
GOC:TermGenie
activation of tRNA degradation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process.
bf
2013-08-22T15:16:19Z
down regulation of mRNA breakdown
down regulation of mRNA catabolic process
down regulation of mRNA catabolism
down regulation of mRNA degradation
down-regulation of mRNA breakdown
down-regulation of mRNA catabolic process
down-regulation of mRNA catabolism
down-regulation of mRNA degradation
downregulation of mRNA breakdown
downregulation of mRNA catabolic process
downregulation of mRNA catabolism
downregulation of mRNA degradation
negative regulation of mRNA breakdown
negative regulation of mRNA catabolism
negative regulation of mRNA degradation
inhibition of mRNA breakdown
inhibition of mRNA catabolic process
inhibition of mRNA catabolism
inhibition of mRNA degradation
biological_process
down regulation of mRNA decay
down-regulation of mRNA decay
downregulation of mRNA decay
inhibition of mRNA decay
negative regulation of mRNA decay
negative regulation of mRNA catabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process.
GOC:TermGenie
GOC:bf
PMID:22626865
down regulation of mRNA breakdown
GOC:TermGenie
down regulation of mRNA catabolic process
GOC:TermGenie
down regulation of mRNA catabolism
GOC:TermGenie
down regulation of mRNA degradation
GOC:TermGenie
down-regulation of mRNA breakdown
GOC:TermGenie
down-regulation of mRNA catabolic process
GOC:TermGenie
down-regulation of mRNA catabolism
GOC:TermGenie
down-regulation of mRNA degradation
GOC:TermGenie
downregulation of mRNA breakdown
GOC:TermGenie
downregulation of mRNA catabolic process
GOC:TermGenie
downregulation of mRNA catabolism
GOC:TermGenie
downregulation of mRNA degradation
GOC:TermGenie
negative regulation of mRNA breakdown
GOC:TermGenie
negative regulation of mRNA catabolism
GOC:TermGenie
negative regulation of mRNA degradation
GOC:TermGenie
inhibition of mRNA breakdown
GOC:TermGenie
inhibition of mRNA catabolic process
GOC:TermGenie
inhibition of mRNA catabolism
GOC:TermGenie
inhibition of mRNA degradation
GOC:TermGenie
down regulation of mRNA decay
GOC:TermGenie
down-regulation of mRNA decay
GOC:TermGenie
downregulation of mRNA decay
GOC:TermGenie
inhibition of mRNA decay
GOC:TermGenie
negative regulation of mRNA decay
GOC:TermGenie
Any process that modulates the frequency, rate or extent of rRNA catabolic process.
bf
2013-08-22T15:20:59Z
regulation of rRNA breakdown
regulation of rRNA catabolism
regulation of rRNA degradation
biological_process
regulation of rRNA catabolic process
Any process that modulates the frequency, rate or extent of rRNA catabolic process.
GOC:TermGenie
GOC:bf
PMID:20160119
regulation of rRNA breakdown
GOC:TermGenie
regulation of rRNA catabolism
GOC:TermGenie
regulation of rRNA degradation
GOC:TermGenie
A process in which a protein is transported to, or maintained in, a location within a cell junction.
tb
2013-09-13T16:55:57Z
protein localisation in cell junction
protein localisation to cell junction
protein localization in cell junction
biological_process
protein localization to cell junction
A process in which a protein is transported to, or maintained in, a location within a cell junction.
GOC:TermGenie
PMID:18332111
protein localisation in cell junction
GOC:TermGenie
protein localisation to cell junction
GOC:TermGenie
protein localization in cell junction
GOC:TermGenie
Any process that modulates the frequency, rate or extent of mRNA binding.
rb
2013-09-13T18:57:15Z
biological_process
regulation of mRNA binding
Any process that modulates the frequency, rate or extent of mRNA binding.
GOC:TermGenie
GOC:rb
PMID:22890846
Any process that activates or increases the frequency, rate or extent of mRNA binding.
rb
2013-09-13T18:57:24Z
up regulation of mRNA binding
up-regulation of mRNA binding
upregulation of mRNA binding
activation of mRNA binding
biological_process
positive regulation of mRNA binding
Any process that activates or increases the frequency, rate or extent of mRNA binding.
GOC:TermGenie
GOC:rb
PMID:22890846
up regulation of mRNA binding
GOC:TermGenie
up-regulation of mRNA binding
GOC:TermGenie
upregulation of mRNA binding
GOC:TermGenie
activation of mRNA binding
GOC:TermGenie
A protein complex which is capable of catalytic activity.
bhm
2013-11-13T16:18:47Z
enzyme complex
cellular_component
catalytic complex
A protein complex which is capable of catalytic activity.
GOC:TermGenie
GOC:bhm
PMID:8077207
enzyme complex
GOC:bhm
GOC:jl
A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.
bhm
2013-11-13T16:23:04Z
cellular_component
transmembrane transporter complex
A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.
GOC:TermGenie
GOC:bhm
PMID:18024586
Any process that modulates the frequency, rate or extent of organelle transport along microtubule.
dph
2013-11-15T20:15:17Z
regulation of microtubule-based organelle localization
biological_process
regulation of organelle transport along microtubule
Any process that modulates the frequency, rate or extent of organelle transport along microtubule.
GOC:TermGenie
GOC:dph
PMID:21147087
regulation of microtubule-based organelle localization
GOC:TermGenie
Any process that modulates the frequency, rate or extent of intracellular signal transduction.
bf
2013-12-02T11:32:52Z
GO:0010627
regulation of intracellular signaling cascade
regulation of intracellular signaling chain
regulation of intracellular protein kinase cascade
regulation of intracellular signal transduction pathway
regulation of signal transmission via intracellular cascade
biological_process
regulation of intracellular signaling pathway
regulation of signal transduction via intracellular signaling cascade
regulation of intracellular signal transduction
Any process that modulates the frequency, rate or extent of intracellular signal transduction.
GOC:TermGenie
GOC:dph
GOC:signaling
GOC:tb
regulation of intracellular signaling cascade
GOC:TermGenie
regulation of intracellular signaling chain
GOC:TermGenie
regulation of intracellular signal transduction pathway
GOC:TermGenie
regulation of signal transmission via intracellular cascade
GOC:TermGenie
regulation of intracellular signaling pathway
GOC:TermGenie
regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
bf
2013-12-02T11:33:01Z
GO:0010741
down regulation of intracellular signal transduction
down regulation of intracellular signaling chain
down-regulation of intracellular signal transduction
down-regulation of intracellular signaling chain
downregulation of intracellular signal transduction
downregulation of intracellular signaling chain
negative regulation of intracellular protein kinase cascade
negative regulation of intracellular signaling cascade
negative regulation of intracellular signaling chain
down regulation of intracellular signal transduction pathway
down regulation of intracellular signaling cascade
down regulation of signal transmission via intracellular cascade
down-regulation of intracellular signal transduction pathway
downregulation of intracellular signal transduction pathway
downregulation of intracellular signaling cascade
downregulation of signal transmission via intracellular cascade
inhibition of intracellular signal transduction
inhibition of intracellular signal transduction pathway
inhibition of intracellular signaling cascade
inhibition of intracellular signaling chain
inhibition of signal transmission via intracellular cascade
negative regulation of intracellular signal transduction pathway
negative regulation of signal transmission via intracellular cascade
biological_process
down regulation of intracellular signaling pathway
down regulation of signal transduction via intracellular signaling cascade
down-regulation of intracellular signaling cascade
down-regulation of intracellular signaling pathway
down-regulation of signal transduction via intracellular signaling cascade
down-regulation of signal transmission via intracellular cascade
downregulation of intracellular signaling pathway
downregulation of signal transduction via intracellular signaling cascade
inhibition of intracellular signaling pathway
inhibition of signal transduction via intracellular signaling cascade
negative regulation of intracellular signaling pathway
negative regulation of signal transduction via intracellular signaling cascade
negative regulation of intracellular signal transduction
Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
GOC:TermGenie
GOC:dph
GOC:signaling
GOC:tb
down regulation of intracellular signal transduction
GOC:TermGenie
down regulation of intracellular signaling chain
GOC:TermGenie
down-regulation of intracellular signal transduction
GOC:TermGenie
down-regulation of intracellular signaling chain
GOC:TermGenie
downregulation of intracellular signal transduction
GOC:TermGenie
downregulation of intracellular signaling chain
GOC:TermGenie
negative regulation of intracellular signaling cascade
GOC:TermGenie
negative regulation of intracellular signaling chain
GOC:TermGenie
down regulation of intracellular signal transduction pathway
GOC:TermGenie
down regulation of intracellular signaling cascade
GOC:TermGenie
down regulation of signal transmission via intracellular cascade
GOC:TermGenie
down-regulation of intracellular signal transduction pathway
GOC:TermGenie
downregulation of intracellular signal transduction pathway
GOC:TermGenie
downregulation of intracellular signaling cascade
GOC:TermGenie
downregulation of signal transmission via intracellular cascade
GOC:TermGenie
inhibition of intracellular signal transduction
GOC:TermGenie
inhibition of intracellular signal transduction pathway
GOC:TermGenie
inhibition of intracellular signaling cascade
GOC:TermGenie
inhibition of intracellular signaling chain
GOC:TermGenie
inhibition of signal transmission via intracellular cascade
GOC:TermGenie
negative regulation of intracellular signal transduction pathway
GOC:TermGenie
negative regulation of signal transmission via intracellular cascade
GOC:TermGenie
down regulation of intracellular signaling pathway
GOC:TermGenie
down regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
down-regulation of intracellular signaling cascade
GOC:TermGenie
down-regulation of intracellular signaling pathway
GOC:TermGenie
down-regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
down-regulation of signal transmission via intracellular cascade
GOC:TermGenie
downregulation of intracellular signaling pathway
GOC:TermGenie
downregulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
inhibition of intracellular signaling pathway
GOC:TermGenie
inhibition of signal transduction via intracellular signaling cascade
GOC:TermGenie
negative regulation of intracellular signaling pathway
GOC:TermGenie
negative regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.
bf
2013-12-02T11:33:10Z
GO:0010740
positive regulation of intracellular signaling chain
up regulation of intracellular signal transduction
up regulation of intracellular signaling chain
up-regulation of intracellular signal transduction
up-regulation of intracellular signaling chain
upregulation of intracellular signal transduction
upregulation of intracellular signaling chain
activation of intracellular signal transduction
activation of intracellular signal transduction pathway
activation of intracellular signaling cascade
activation of intracellular signaling chain
activation of signal transmission via intracellular cascade
positive regulation of intracellular protein kinase cascade
positive regulation of intracellular signal transduction pathway
positive regulation of signal transmission via intracellular cascade
up regulation of intracellular signal transduction pathway
up regulation of signal transmission via intracellular cascade
up-regulation of intracellular signal transduction pathway
up-regulation of signal transmission via intracellular cascade
upregulation of intracellular signal transduction pathway
upregulation of signal transmission via intracellular cascade
biological_process
activation of intracellular signaling pathway
activation of signal transduction via intracellular signaling cascade
positive regulation of intracellular signaling cascade
positive regulation of intracellular signaling pathway
positive regulation of signal transduction via intracellular signaling cascade
up regulation of intracellular signaling cascade
up regulation of intracellular signaling pathway
up regulation of signal transduction via intracellular signaling cascade
up-regulation of intracellular signaling cascade
up-regulation of intracellular signaling pathway
up-regulation of signal transduction via intracellular signaling cascade
upregulation of intracellular signaling cascade
upregulation of intracellular signaling pathway
upregulation of signal transduction via intracellular signaling cascade
positive regulation of intracellular signal transduction
Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.
GOC:BHF
GOC:TermGenie
GOC:dph
GOC:signaling
GOC:tb
positive regulation of intracellular signaling chain
GOC:TermGenie
up regulation of intracellular signal transduction
GOC:TermGenie
up regulation of intracellular signaling chain
GOC:TermGenie
up-regulation of intracellular signal transduction
GOC:TermGenie
up-regulation of intracellular signaling chain
GOC:TermGenie
upregulation of intracellular signal transduction
GOC:TermGenie
upregulation of intracellular signaling chain
GOC:TermGenie
activation of intracellular signal transduction
GOC:TermGenie
activation of intracellular signal transduction pathway
GOC:TermGenie
activation of intracellular signaling cascade
GOC:TermGenie
activation of intracellular signaling chain
GOC:TermGenie
activation of signal transmission via intracellular cascade
GOC:TermGenie
positive regulation of intracellular signal transduction pathway
GOC:TermGenie
positive regulation of signal transmission via intracellular cascade
GOC:TermGenie
up regulation of intracellular signal transduction pathway
GOC:TermGenie
up regulation of signal transmission via intracellular cascade
GOC:TermGenie
up-regulation of intracellular signal transduction pathway
GOC:TermGenie
up-regulation of signal transmission via intracellular cascade
GOC:TermGenie
upregulation of intracellular signal transduction pathway
GOC:TermGenie
upregulation of signal transmission via intracellular cascade
GOC:TermGenie
activation of intracellular signaling pathway
GOC:TermGenie
activation of signal transduction via intracellular signaling cascade
GOC:TermGenie
positive regulation of intracellular signaling cascade
GOC:TermGenie
positive regulation of intracellular signaling pathway
GOC:TermGenie
positive regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
up regulation of intracellular signaling cascade
GOC:TermGenie
up regulation of intracellular signaling pathway
GOC:TermGenie
up regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
up-regulation of intracellular signaling cascade
GOC:TermGenie
up-regulation of intracellular signaling pathway
GOC:TermGenie
up-regulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
upregulation of intracellular signaling cascade
GOC:TermGenie
upregulation of intracellular signaling pathway
GOC:TermGenie
upregulation of signal transduction via intracellular signaling cascade
GOC:TermGenie
A process in which a protein is transported to, or maintained in, a location within a nucleolus.
mah
2013-12-10T16:25:28Z
protein localisation in nucleolus
protein localisation to nucleolus
protein localization in nucleolus
biological_process
protein localization to nucleolus
A process in which a protein is transported to, or maintained in, a location within a nucleolus.
GOC:TermGenie
PMID:22809626
protein localisation in nucleolus
GOC:TermGenie
protein localisation to nucleolus
GOC:TermGenie
protein localization in nucleolus
GOC:TermGenie
A localization which involves another organism.
jl
2013-12-18T13:51:13Z
multi organism localization
biological_process
multi-organism localization
A localization which involves another organism.
GOC:TermGenie
GOC:jl
GO_REF:0000089
multi organism localization
GOC:TermGenie
A cellular localization which involves another organism.
jl
2013-12-18T14:04:41Z
multi organism cellular localization
biological_process
multi-organism cellular localization
A cellular localization which involves another organism.
GOC:TermGenie
GOC:jl
GO_REF:0000089
multi organism cellular localization
GOC:TermGenie
An organelle organization which involves another organism.
jl
2013-12-19T15:26:08Z
multi organism organelle organization
biological_process
multi-organism organelle organization
An organelle organization which involves another organism.
GOC:TermGenie
GOC:jl
GO_REF:0000089
multi organism organelle organization
GOC:TermGenie
A nuclear import which involves another organism.
jl
2013-12-19T15:26:43Z
multi organism nuclear import
biological_process
multi-organism nuclear import
A nuclear import which involves another organism.
GOC:TermGenie
GOC:jl
GO_REF:0000089
multi organism nuclear import
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.
jl
2014-02-05T16:32:01Z
down regulation of RNA anabolism
down regulation of RNA biosynthesis
down regulation of RNA biosynthetic process
down regulation of RNA formation
down regulation of RNA synthesis
down-regulation of RNA anabolism
down-regulation of RNA biosynthesis
down-regulation of RNA biosynthetic process
down-regulation of RNA formation
down-regulation of RNA synthesis
downregulation of RNA anabolism
downregulation of RNA biosynthesis
downregulation of RNA biosynthetic process
downregulation of RNA formation
downregulation of RNA synthesis
negative regulation of RNA anabolism
negative regulation of RNA biosynthesis
negative regulation of RNA formation
negative regulation of RNA synthesis
inhibition of RNA anabolism
inhibition of RNA biosynthesis
inhibition of RNA biosynthetic process
inhibition of RNA formation
inhibition of RNA synthesis
biological_process
negative regulation of RNA biosynthetic process
Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.
GO:jl
GOC:TermGenie
GO_REF:0000058
down regulation of RNA anabolism
GOC:TermGenie
down regulation of RNA biosynthesis
GOC:TermGenie
down regulation of RNA biosynthetic process
GOC:TermGenie
down regulation of RNA formation
GOC:TermGenie
down regulation of RNA synthesis
GOC:TermGenie
down-regulation of RNA anabolism
GOC:TermGenie
down-regulation of RNA biosynthesis
GOC:TermGenie
down-regulation of RNA biosynthetic process
GOC:TermGenie
down-regulation of RNA formation
GOC:TermGenie
down-regulation of RNA synthesis
GOC:TermGenie
downregulation of RNA anabolism
GOC:TermGenie
downregulation of RNA biosynthesis
GOC:TermGenie
downregulation of RNA biosynthetic process
GOC:TermGenie
downregulation of RNA formation
GOC:TermGenie
downregulation of RNA synthesis
GOC:TermGenie
negative regulation of RNA anabolism
GOC:TermGenie
negative regulation of RNA biosynthesis
GOC:TermGenie
negative regulation of RNA formation
GOC:TermGenie
negative regulation of RNA synthesis
GOC:TermGenie
inhibition of RNA anabolism
GOC:TermGenie
inhibition of RNA biosynthesis
GOC:TermGenie
inhibition of RNA biosynthetic process
GOC:TermGenie
inhibition of RNA formation
GOC:TermGenie
inhibition of RNA synthesis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.
jl
2014-02-05T16:32:10Z
positive regulation of RNA anabolism
positive regulation of RNA biosynthesis
positive regulation of RNA formation
positive regulation of RNA synthesis
up regulation of RNA anabolism
up regulation of RNA biosynthesis
up regulation of RNA biosynthetic process
up regulation of RNA formation
up regulation of RNA synthesis
up-regulation of RNA anabolism
up-regulation of RNA biosynthesis
up-regulation of RNA biosynthetic process
up-regulation of RNA formation
up-regulation of RNA synthesis
upregulation of RNA anabolism
upregulation of RNA biosynthesis
upregulation of RNA biosynthetic process
upregulation of RNA formation
upregulation of RNA synthesis
activation of RNA anabolism
activation of RNA biosynthesis
activation of RNA biosynthetic process
activation of RNA formation
activation of RNA synthesis
biological_process
positive regulation of RNA biosynthetic process
Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.
GO:jl
GOC:TermGenie
GO_REF:0000058
positive regulation of RNA anabolism
GOC:TermGenie
positive regulation of RNA biosynthesis
GOC:TermGenie
positive regulation of RNA formation
GOC:TermGenie
positive regulation of RNA synthesis
GOC:TermGenie
up regulation of RNA anabolism
GOC:TermGenie
up regulation of RNA biosynthesis
GOC:TermGenie
up regulation of RNA biosynthetic process
GOC:TermGenie
up regulation of RNA formation
GOC:TermGenie
up regulation of RNA synthesis
GOC:TermGenie
up-regulation of RNA anabolism
GOC:TermGenie
up-regulation of RNA biosynthesis
GOC:TermGenie
up-regulation of RNA biosynthetic process
GOC:TermGenie
up-regulation of RNA formation
GOC:TermGenie
up-regulation of RNA synthesis
GOC:TermGenie
upregulation of RNA anabolism
GOC:TermGenie
upregulation of RNA biosynthesis
GOC:TermGenie
upregulation of RNA biosynthetic process
GOC:TermGenie
upregulation of RNA formation
GOC:TermGenie
upregulation of RNA synthesis
GOC:TermGenie
activation of RNA anabolism
GOC:TermGenie
activation of RNA biosynthesis
GOC:TermGenie
activation of RNA biosynthetic process
GOC:TermGenie
activation of RNA formation
GOC:TermGenie
activation of RNA synthesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein localization to microtubule.
tb
2014-03-27T22:07:12Z
regulation of protein localisation to microtubule
biological_process
regulation of protein localization to microtubule
Any process that modulates the frequency, rate or extent of protein localization to microtubule.
GOC:TermGenie
GOC:vw
GO_REF:0000058
PMID:23087209
regulation of protein localisation to microtubule
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule.
tb
2014-03-27T22:07:18Z
down regulation of protein localisation to microtubule
down regulation of protein localization to microtubule
down-regulation of protein localisation to microtubule
down-regulation of protein localization to microtubule
downregulation of protein localisation to microtubule
downregulation of protein localization to microtubule
negative regulation of protein localisation to microtubule
inhibition of protein localisation to microtubule
inhibition of protein localization to microtubule
biological_process
negative regulation of protein localization to microtubule
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule.
GOC:TermGenie
GOC:vw
GO_REF:0000058
PMID:23087209
down regulation of protein localisation to microtubule
GOC:TermGenie
down regulation of protein localization to microtubule
GOC:TermGenie
down-regulation of protein localisation to microtubule
GOC:TermGenie
down-regulation of protein localization to microtubule
GOC:TermGenie
downregulation of protein localisation to microtubule
GOC:TermGenie
downregulation of protein localization to microtubule
GOC:TermGenie
negative regulation of protein localisation to microtubule
GOC:TermGenie
inhibition of protein localisation to microtubule
GOC:TermGenie
inhibition of protein localization to microtubule
GOC:TermGenie
Any process that modulates the frequency, rate or extent of nuclear migration along microtubule.
vw
2014-04-01T13:50:23Z
regulation of nuclear movement, microtubule-mediated
regulation of nucleus migration
regulation of microtubule cytoskeleton-dependent nuclear positioning
regulation of microtubule cytoskeleton-dependent nucleus positioning
regulation of microtubule-dependent nuclear positioning
regulation of microtubule-dependent nucleus positioning
regulation of microtubule-mediated nuclear migration
regulation of nuclear migration, microtubule-mediated
regulation of transport of nucleus by microtubules
regulation of transport of nucleus, microtubule-mediated
biological_process
regulation of nuclear migration along microtubule
Any process that modulates the frequency, rate or extent of nuclear migration along microtubule.
GOC:TermGenie
GO_REF:0000058
PMID:23087209
regulation of nuclear movement, microtubule-mediated
GOC:TermGenie
regulation of nucleus migration
GOC:TermGenie
regulation of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
regulation of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
regulation of microtubule-dependent nuclear positioning
GOC:TermGenie
regulation of microtubule-dependent nucleus positioning
GOC:TermGenie
regulation of microtubule-mediated nuclear migration
GOC:TermGenie
regulation of nuclear migration, microtubule-mediated
GOC:TermGenie
regulation of transport of nucleus by microtubules
GOC:TermGenie
regulation of transport of nucleus, microtubule-mediated
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule.
vw
2014-04-01T13:50:29Z
down regulation of microtubule cytoskeleton-dependent nuclear positioning
down regulation of microtubule cytoskeleton-dependent nucleus positioning
down regulation of microtubule-dependent nuclear positioning
down regulation of microtubule-dependent nucleus positioning
down regulation of microtubule-mediated nuclear migration
down regulation of nuclear migration along microtubule
down regulation of nuclear migration, microtubule-mediated
down regulation of transport of nucleus by microtubules
down regulation of transport of nucleus, microtubule-mediated
down-regulation of microtubule cytoskeleton-dependent nuclear positioning
down-regulation of microtubule cytoskeleton-dependent nucleus positioning
down-regulation of microtubule-dependent nuclear positioning
down-regulation of microtubule-dependent nucleus positioning
down-regulation of microtubule-mediated nuclear migration
down-regulation of nuclear migration along microtubule
down-regulation of nuclear migration, microtubule-mediated
down-regulation of transport of nucleus by microtubules
down-regulation of transport of nucleus, microtubule-mediated
downregulation of microtubule cytoskeleton-dependent nuclear positioning
downregulation of microtubule cytoskeleton-dependent nucleus positioning
downregulation of microtubule-dependent nuclear positioning
downregulation of microtubule-dependent nucleus positioning
downregulation of microtubule-mediated nuclear migration
downregulation of nuclear migration along microtubule
downregulation of nuclear migration, microtubule-mediated
downregulation of transport of nucleus by microtubules
downregulation of transport of nucleus, microtubule-mediated
negative regulation of microtubule cytoskeleton-dependent nuclear positioning
negative regulation of microtubule cytoskeleton-dependent nucleus positioning
negative regulation of microtubule-dependent nuclear positioning
negative regulation of microtubule-dependent nucleus positioning
negative regulation of microtubule-mediated nuclear migration
negative regulation of nuclear migration, microtubule-mediated
negative regulation of transport of nucleus by microtubules
negative regulation of transport of nucleus, microtubule-mediated
inhibition of microtubule cytoskeleton-dependent nuclear positioning
inhibition of microtubule cytoskeleton-dependent nucleus positioning
inhibition of microtubule-dependent nuclear positioning
inhibition of microtubule-dependent nucleus positioning
inhibition of microtubule-mediated nuclear migration
inhibition of nuclear migration along microtubule
inhibition of nuclear migration, microtubule-mediated
inhibition of transport of nucleus by microtubules
inhibition of transport of nucleus, microtubule-mediated
biological_process
negative regulation of nuclear migration along microtubule
Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule.
GOC:TermGenie
GO_REF:0000058
PMID:23087209
down regulation of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
down regulation of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
down regulation of microtubule-dependent nuclear positioning
GOC:TermGenie
down regulation of microtubule-dependent nucleus positioning
GOC:TermGenie
down regulation of microtubule-mediated nuclear migration
GOC:TermGenie
down regulation of nuclear migration along microtubule
GOC:TermGenie
down regulation of nuclear migration, microtubule-mediated
GOC:TermGenie
down regulation of transport of nucleus by microtubules
GOC:TermGenie
down regulation of transport of nucleus, microtubule-mediated
GOC:TermGenie
down-regulation of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
down-regulation of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
down-regulation of microtubule-dependent nuclear positioning
GOC:TermGenie
down-regulation of microtubule-dependent nucleus positioning
GOC:TermGenie
down-regulation of microtubule-mediated nuclear migration
GOC:TermGenie
down-regulation of nuclear migration along microtubule
GOC:TermGenie
down-regulation of nuclear migration, microtubule-mediated
GOC:TermGenie
down-regulation of transport of nucleus by microtubules
GOC:TermGenie
down-regulation of transport of nucleus, microtubule-mediated
GOC:TermGenie
downregulation of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
downregulation of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
downregulation of microtubule-dependent nuclear positioning
GOC:TermGenie
downregulation of microtubule-dependent nucleus positioning
GOC:TermGenie
downregulation of microtubule-mediated nuclear migration
GOC:TermGenie
downregulation of nuclear migration along microtubule
GOC:TermGenie
downregulation of nuclear migration, microtubule-mediated
GOC:TermGenie
downregulation of transport of nucleus by microtubules
GOC:TermGenie
downregulation of transport of nucleus, microtubule-mediated
GOC:TermGenie
negative regulation of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
negative regulation of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
negative regulation of microtubule-dependent nuclear positioning
GOC:TermGenie
negative regulation of microtubule-dependent nucleus positioning
GOC:TermGenie
negative regulation of microtubule-mediated nuclear migration
GOC:TermGenie
negative regulation of nuclear migration, microtubule-mediated
GOC:TermGenie
negative regulation of transport of nucleus by microtubules
GOC:TermGenie
negative regulation of transport of nucleus, microtubule-mediated
GOC:TermGenie
inhibition of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
inhibition of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
inhibition of microtubule-dependent nuclear positioning
GOC:TermGenie
inhibition of microtubule-dependent nucleus positioning
GOC:TermGenie
inhibition of microtubule-mediated nuclear migration
GOC:TermGenie
inhibition of nuclear migration along microtubule
GOC:TermGenie
inhibition of nuclear migration, microtubule-mediated
GOC:TermGenie
inhibition of transport of nucleus by microtubules
GOC:TermGenie
inhibition of transport of nucleus, microtubule-mediated
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.
vw
2014-04-01T13:50:35Z
positive regulation of microtubule cytoskeleton-dependent nuclear positioning
positive regulation of microtubule cytoskeleton-dependent nucleus positioning
positive regulation of microtubule-dependent nuclear positioning
positive regulation of microtubule-dependent nucleus positioning
positive regulation of microtubule-mediated nuclear migration
positive regulation of nuclear migration, microtubule-mediated
positive regulation of transport of nucleus by microtubules
positive regulation of transport of nucleus, microtubule-mediated
up regulation of microtubule cytoskeleton-dependent nuclear positioning
up regulation of microtubule cytoskeleton-dependent nucleus positioning
up regulation of microtubule-dependent nuclear positioning
up regulation of microtubule-dependent nucleus positioning
up regulation of microtubule-mediated nuclear migration
up regulation of nuclear migration along microtubule
up regulation of nuclear migration, microtubule-mediated
up regulation of transport of nucleus by microtubules
up regulation of transport of nucleus, microtubule-mediated
up-regulation of microtubule cytoskeleton-dependent nuclear positioning
up-regulation of microtubule cytoskeleton-dependent nucleus positioning
up-regulation of microtubule-dependent nuclear positioning
up-regulation of microtubule-dependent nucleus positioning
up-regulation of microtubule-mediated nuclear migration
up-regulation of nuclear migration along microtubule
up-regulation of nuclear migration, microtubule-mediated
up-regulation of transport of nucleus by microtubules
up-regulation of transport of nucleus, microtubule-mediated
upregulation of microtubule cytoskeleton-dependent nuclear positioning
upregulation of microtubule cytoskeleton-dependent nucleus positioning
upregulation of microtubule-dependent nuclear positioning
upregulation of microtubule-dependent nucleus positioning
upregulation of microtubule-mediated nuclear migration
upregulation of nuclear migration along microtubule
upregulation of nuclear migration, microtubule-mediated
upregulation of transport of nucleus by microtubules
upregulation of transport of nucleus, microtubule-mediated
activation of microtubule cytoskeleton-dependent nuclear positioning
activation of microtubule cytoskeleton-dependent nucleus positioning
activation of microtubule-dependent nuclear positioning
activation of microtubule-dependent nucleus positioning
activation of microtubule-mediated nuclear migration
activation of nuclear migration along microtubule
activation of nuclear migration, microtubule-mediated
activation of transport of nucleus by microtubules
activation of transport of nucleus, microtubule-mediated
biological_process
positive regulation of nuclear migration along microtubule
Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.
GOC:TermGenie
GO_REF:0000058
PMID:23087209
positive regulation of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
positive regulation of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
positive regulation of microtubule-dependent nuclear positioning
GOC:TermGenie
positive regulation of microtubule-dependent nucleus positioning
GOC:TermGenie
positive regulation of microtubule-mediated nuclear migration
GOC:TermGenie
positive regulation of nuclear migration, microtubule-mediated
GOC:TermGenie
positive regulation of transport of nucleus by microtubules
GOC:TermGenie
positive regulation of transport of nucleus, microtubule-mediated
GOC:TermGenie
up regulation of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
up regulation of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
up regulation of microtubule-dependent nuclear positioning
GOC:TermGenie
up regulation of microtubule-dependent nucleus positioning
GOC:TermGenie
up regulation of microtubule-mediated nuclear migration
GOC:TermGenie
up regulation of nuclear migration along microtubule
GOC:TermGenie
up regulation of nuclear migration, microtubule-mediated
GOC:TermGenie
up regulation of transport of nucleus by microtubules
GOC:TermGenie
up regulation of transport of nucleus, microtubule-mediated
GOC:TermGenie
up-regulation of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
up-regulation of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
up-regulation of microtubule-dependent nuclear positioning
GOC:TermGenie
up-regulation of microtubule-dependent nucleus positioning
GOC:TermGenie
up-regulation of microtubule-mediated nuclear migration
GOC:TermGenie
up-regulation of nuclear migration along microtubule
GOC:TermGenie
up-regulation of nuclear migration, microtubule-mediated
GOC:TermGenie
up-regulation of transport of nucleus by microtubules
GOC:TermGenie
up-regulation of transport of nucleus, microtubule-mediated
GOC:TermGenie
upregulation of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
upregulation of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
upregulation of microtubule-dependent nuclear positioning
GOC:TermGenie
upregulation of microtubule-dependent nucleus positioning
GOC:TermGenie
upregulation of microtubule-mediated nuclear migration
GOC:TermGenie
upregulation of nuclear migration along microtubule
GOC:TermGenie
upregulation of nuclear migration, microtubule-mediated
GOC:TermGenie
upregulation of transport of nucleus by microtubules
GOC:TermGenie
upregulation of transport of nucleus, microtubule-mediated
GOC:TermGenie
activation of microtubule cytoskeleton-dependent nuclear positioning
GOC:TermGenie
activation of microtubule cytoskeleton-dependent nucleus positioning
GOC:TermGenie
activation of microtubule-dependent nuclear positioning
GOC:TermGenie
activation of microtubule-dependent nucleus positioning
GOC:TermGenie
activation of microtubule-mediated nuclear migration
GOC:TermGenie
activation of nuclear migration along microtubule
GOC:TermGenie
activation of nuclear migration, microtubule-mediated
GOC:TermGenie
activation of transport of nucleus by microtubules
GOC:TermGenie
activation of transport of nucleus, microtubule-mediated
GOC:TermGenie
Any microtubule cytoskeleton organization that is involved in mitosis.
vw
2014-04-02T14:19:38Z
microtubule cytoskeleton organisation involved in mitosis
microtubule dynamics involved in mitosis
biological_process
microtubule cytoskeleton organization and biogenesis involved in mitosis
microtubule cytoskeleton organization involved in mitosis
Any microtubule cytoskeleton organization that is involved in mitosis.
GOC:TermGenie
GO_REF:0000060
PMID:18799626
microtubule cytoskeleton organisation involved in mitosis
GOC:TermGenie
microtubule dynamics involved in mitosis
GOC:TermGenie
microtubule cytoskeleton organization and biogenesis involved in mitosis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of proteasome-activating ATPase activity.
di
2014-04-04T17:35:23Z
regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
regulation of proteasomal ATPase activity
regulation of proteasome channel gating activity
regulation of proteasome channel opening activity
biological_process
regulation of proteasome-activating ATPase activity
Any process that modulates the frequency, rate or extent of proteasome-activating ATPase activity.
GOC:TermGenie
GOC:di
GO_REF:0000059
PMID:23995839
regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
regulation of proteasomal ATPase activity
GOC:TermGenie
regulation of proteasome channel gating activity
GOC:TermGenie
regulation of proteasome channel opening activity
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of proteasome-activating ATPase activity.
di
2014-04-04T17:35:30Z
down regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
down regulation of proteasomal ATPase activity
down regulation of proteasome-activating ATPase activity
down-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
down-regulation of proteasomal ATPase activity
down-regulation of proteasome-activating ATPase activity
downregulation of ATPase involved in positive regulation of proteasomal protein catabolic process
downregulation of proteasomal ATPase activity
downregulation of proteasome-activating ATPase activity
negative regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
negative regulation of proteasomal ATPase activity
down regulation of proteasome channel gating activity
down regulation of proteasome channel opening activity
down-regulation of proteasome channel gating activity
down-regulation of proteasome channel opening activity
downregulation of proteasome channel gating activity
downregulation of proteasome channel opening activity
inhibition of ATPase involved in positive regulation of proteasomal protein catabolic process
inhibition of proteasomal ATPase activity
inhibition of proteasome channel gating activity
inhibition of proteasome channel opening activity
inhibition of proteasome-activating ATPase activity
negative regulation of proteasome channel gating activity
negative regulation of proteasome channel opening activity
biological_process
negative regulation of proteasome-activating ATPase activity
Any process that stops, prevents or reduces the frequency, rate or extent of proteasome-activating ATPase activity.
GOC:TermGenie
GOC:di
GO_REF:0000059
PMID:23995839
down regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
down regulation of proteasomal ATPase activity
GOC:TermGenie
down regulation of proteasome-activating ATPase activity
GOC:TermGenie
down-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
down-regulation of proteasomal ATPase activity
GOC:TermGenie
down-regulation of proteasome-activating ATPase activity
GOC:TermGenie
downregulation of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
downregulation of proteasomal ATPase activity
GOC:TermGenie
downregulation of proteasome-activating ATPase activity
GOC:TermGenie
negative regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
negative regulation of proteasomal ATPase activity
GOC:TermGenie
down regulation of proteasome channel gating activity
GOC:TermGenie
down regulation of proteasome channel opening activity
GOC:TermGenie
down-regulation of proteasome channel gating activity
GOC:TermGenie
down-regulation of proteasome channel opening activity
GOC:TermGenie
downregulation of proteasome channel gating activity
GOC:TermGenie
downregulation of proteasome channel opening activity
GOC:TermGenie
inhibition of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
inhibition of proteasomal ATPase activity
GOC:TermGenie
inhibition of proteasome channel gating activity
GOC:TermGenie
inhibition of proteasome channel opening activity
GOC:TermGenie
inhibition of proteasome-activating ATPase activity
GOC:TermGenie
negative regulation of proteasome channel gating activity
GOC:TermGenie
negative regulation of proteasome channel opening activity
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of proteasome-activating ATPase activity.
di
2014-04-04T17:35:36Z
positive regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
positive regulation of proteasomal ATPase activity
up regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
up regulation of proteasomal ATPase activity
up regulation of proteasome-activating ATPase activity
up-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
up-regulation of proteasomal ATPase activity
up-regulation of proteasome-activating ATPase activity
upregulation of ATPase involved in positive regulation of proteasomal protein catabolic process
upregulation of proteasomal ATPase activity
upregulation of proteasome-activating ATPase activity
activation of ATPase involved in positive regulation of proteasomal protein catabolic process
activation of proteasomal ATPase activity
activation of proteasome channel gating activity
activation of proteasome channel opening activity
activation of proteasome-activating ATPase activity
positive regulation of proteasome channel gating activity
positive regulation of proteasome channel opening activity
up regulation of proteasome channel gating activity
up regulation of proteasome channel opening activity
up-regulation of proteasome channel gating activity
up-regulation of proteasome channel opening activity
upregulation of proteasome channel gating activity
upregulation of proteasome channel opening activity
biological_process
positive regulation of proteasome-activating ATPase activity
Any process that activates or increases the frequency, rate or extent of proteasome-activating ATPase activity.
GOC:TermGenie
GOC:di
GO_REF:0000059
PMID:23995839
positive regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
positive regulation of proteasomal ATPase activity
GOC:TermGenie
up regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
up regulation of proteasomal ATPase activity
GOC:TermGenie
up regulation of proteasome-activating ATPase activity
GOC:TermGenie
up-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
up-regulation of proteasomal ATPase activity
GOC:TermGenie
up-regulation of proteasome-activating ATPase activity
GOC:TermGenie
upregulation of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
upregulation of proteasomal ATPase activity
GOC:TermGenie
upregulation of proteasome-activating ATPase activity
GOC:TermGenie
activation of ATPase involved in positive regulation of proteasomal protein catabolic process
GOC:TermGenie
activation of proteasomal ATPase activity
GOC:TermGenie
activation of proteasome channel gating activity
GOC:TermGenie
activation of proteasome channel opening activity
GOC:TermGenie
activation of proteasome-activating ATPase activity
GOC:TermGenie
positive regulation of proteasome channel gating activity
GOC:TermGenie
positive regulation of proteasome channel opening activity
GOC:TermGenie
up regulation of proteasome channel gating activity
GOC:TermGenie
up regulation of proteasome channel opening activity
GOC:TermGenie
up-regulation of proteasome channel gating activity
GOC:TermGenie
up-regulation of proteasome channel opening activity
GOC:TermGenie
upregulation of proteasome channel gating activity
GOC:TermGenie
upregulation of proteasome channel opening activity
GOC:TermGenie
Any process that modulates the frequency, rate or extent of supramolecular fiber organization.
rl
2014-04-15T16:46:36Z
biological_process
regulation of fibril organisation
HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro
regulation of supramolecular fiber organization
Any process that modulates the frequency, rate or extent of supramolecular fiber organization.
GOC:PARL
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:23921388
regulation of fibril organisation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.
rl
2014-04-15T16:46:42Z
inhibition of fibril organisation
inhibition of fibril organization
biological_process
down regulation of fibril organisation
down regulation of fibril organization
down-regulation of fibril organisation
down-regulation of fibril organization
downregulation of fibril organisation
downregulation of fibril organization
negative regulation of fibril organisation
HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro
negative regulation of supramolecular fiber organization
Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.
GOC:PARL
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:23921388
inhibition of fibril organisation
GOC:TermGenie
inhibition of fibril organization
GOC:TermGenie
down regulation of fibril organisation
GOC:TermGenie
down regulation of fibril organization
GOC:TermGenie
down-regulation of fibril organisation
GOC:TermGenie
down-regulation of fibril organization
GOC:TermGenie
downregulation of fibril organisation
GOC:TermGenie
downregulation of fibril organization
GOC:TermGenie
negative regulation of fibril organisation
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization.
rl
2014-04-15T16:46:48Z
activation of fibril organisation
activation of fibril organization
biological_process
positive regulation of fibril organisation
up regulation of fibril organisation
up regulation of fibril organization
up-regulation of fibril organisation
up-regulation of fibril organization
upregulation of fibril organisation
upregulation of fibril organization
HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro
positive regulation of supramolecular fiber organization
Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization.
GOC:PARL
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:23921388
activation of fibril organisation
GOC:TermGenie
activation of fibril organization
GOC:TermGenie
positive regulation of fibril organisation
GOC:TermGenie
up regulation of fibril organisation
GOC:TermGenie
up regulation of fibril organization
GOC:TermGenie
up-regulation of fibril organisation
GOC:TermGenie
up-regulation of fibril organization
GOC:TermGenie
upregulation of fibril organisation
GOC:TermGenie
upregulation of fibril organization
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.
sjp
2014-05-02T08:59:18Z
positive regulation of ER to Golgi transport
positive regulation of endoplasmic reticulum to Golgi transport
positive regulation of endoplasmic reticulum to Golgi vesicle-mediated transport
positive regulation of rough ER to cis-Golgi transport
positive regulation of rough ER to cis-Golgi vesicle-mediated transport
positive regulation of rough endoplasmic reticulum to cis-Golgi transport
positive regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
up regulation of ER to Golgi transport
up regulation of ER to Golgi vesicle-mediated transport
up regulation of endoplasmic reticulum to Golgi transport
up regulation of endoplasmic reticulum to Golgi vesicle-mediated transport
up regulation of rough ER to cis-Golgi transport
up regulation of rough ER to cis-Golgi vesicle-mediated transport
up regulation of rough endoplasmic reticulum to cis-Golgi transport
up regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
up-regulation of ER to Golgi transport
up-regulation of ER to Golgi vesicle-mediated transport
up-regulation of endoplasmic reticulum to Golgi transport
up-regulation of endoplasmic reticulum to Golgi vesicle-mediated transport
up-regulation of rough ER to cis-Golgi transport
up-regulation of rough ER to cis-Golgi vesicle-mediated transport
up-regulation of rough endoplasmic reticulum to cis-Golgi transport
up-regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
upregulation of ER to Golgi transport
upregulation of ER to Golgi vesicle-mediated transport
upregulation of endoplasmic reticulum to Golgi transport
upregulation of endoplasmic reticulum to Golgi vesicle-mediated transport
upregulation of rough ER to cis-Golgi transport
upregulation of rough ER to cis-Golgi vesicle-mediated transport
upregulation of rough endoplasmic reticulum to cis-Golgi transport
upregulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
activation of ER to Golgi transport
activation of ER to Golgi vesicle-mediated transport
activation of endoplasmic reticulum to Golgi transport
activation of endoplasmic reticulum to Golgi vesicle-mediated transport
activation of rough ER to cis-Golgi transport
activation of rough ER to cis-Golgi vesicle-mediated transport
activation of rough endoplasmic reticulum to cis-Golgi transport
activation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
biological_process
positive regulation of ER to Golgi vesicle-mediated transport
Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.
GOC:TermGenie
GOC:sjp
GO_REF:0000058
PMID:17855360
positive regulation of ER to Golgi transport
GOC:TermGenie
positive regulation of endoplasmic reticulum to Golgi transport
GOC:TermGenie
positive regulation of endoplasmic reticulum to Golgi vesicle-mediated transport
GOC:TermGenie
positive regulation of rough ER to cis-Golgi transport
GOC:TermGenie
positive regulation of rough ER to cis-Golgi vesicle-mediated transport
GOC:TermGenie
positive regulation of rough endoplasmic reticulum to cis-Golgi transport
GOC:TermGenie
positive regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
GOC:TermGenie
up regulation of ER to Golgi transport
GOC:TermGenie
up regulation of ER to Golgi vesicle-mediated transport
GOC:TermGenie
up regulation of endoplasmic reticulum to Golgi transport
GOC:TermGenie
up regulation of endoplasmic reticulum to Golgi vesicle-mediated transport
GOC:TermGenie
up regulation of rough ER to cis-Golgi transport
GOC:TermGenie
up regulation of rough ER to cis-Golgi vesicle-mediated transport
GOC:TermGenie
up regulation of rough endoplasmic reticulum to cis-Golgi transport
GOC:TermGenie
up regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
GOC:TermGenie
up-regulation of ER to Golgi transport
GOC:TermGenie
up-regulation of ER to Golgi vesicle-mediated transport
GOC:TermGenie
up-regulation of endoplasmic reticulum to Golgi transport
GOC:TermGenie
up-regulation of endoplasmic reticulum to Golgi vesicle-mediated transport
GOC:TermGenie
up-regulation of rough ER to cis-Golgi transport
GOC:TermGenie
up-regulation of rough ER to cis-Golgi vesicle-mediated transport
GOC:TermGenie
up-regulation of rough endoplasmic reticulum to cis-Golgi transport
GOC:TermGenie
up-regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
GOC:TermGenie
upregulation of ER to Golgi transport
GOC:TermGenie
upregulation of ER to Golgi vesicle-mediated transport
GOC:TermGenie
upregulation of endoplasmic reticulum to Golgi transport
GOC:TermGenie
upregulation of endoplasmic reticulum to Golgi vesicle-mediated transport
GOC:TermGenie
upregulation of rough ER to cis-Golgi transport
GOC:TermGenie
upregulation of rough ER to cis-Golgi vesicle-mediated transport
GOC:TermGenie
upregulation of rough endoplasmic reticulum to cis-Golgi transport
GOC:TermGenie
upregulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
GOC:TermGenie
activation of ER to Golgi transport
GOC:TermGenie
activation of ER to Golgi vesicle-mediated transport
GOC:TermGenie
activation of endoplasmic reticulum to Golgi transport
GOC:TermGenie
activation of endoplasmic reticulum to Golgi vesicle-mediated transport
GOC:TermGenie
activation of rough ER to cis-Golgi transport
GOC:TermGenie
activation of rough ER to cis-Golgi vesicle-mediated transport
GOC:TermGenie
activation of rough endoplasmic reticulum to cis-Golgi transport
GOC:TermGenie
activation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport
GOC:TermGenie
The disaggregation of an organelle into its constituent components.
jl
2014-05-13T12:36:03Z
organelle degradation
biological_process
organelle disassembly
The disaggregation of an organelle into its constituent components.
GOC:TermGenie
GO_REF:0000079
The disaggregation of a proteasome complex into its constituent components.
jl
2014-05-13T12:41:59Z
proteasome degradation
proteasome disassembly
26S proteasome disassembly
biological_process
proteasome complex disassembly
The disaggregation of a proteasome complex into its constituent components.
GOC:TermGenie
GO_REF:0000079
proteasome disassembly
GOC:TermGenie
26S proteasome disassembly
GOC:TermGenie
A process that is part of the mitotic cell cycle.
jl
2014-05-22T14:22:34Z
biological_process
mitotic cell cycle process
A process that is part of the mitotic cell cycle.
GOC:TermGenie
GOC:mtg_cell_cycle
GO_REF:0000060
Any process that modulates the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
rl
2014-05-22T18:00:45Z
regulation of peptidolysis involved in cellular protein catabolic process
regulation of peptidolysis involved in cellular protein catabolism
biological_process
regulation of peptidolysis during cellular protein catabolic process
regulation of peptidolysis during cellular protein catabolism
regulation of proteolysis during cellular protein catabolic process
regulation of proteolysis during cellular protein catabolism
overexpression of cathepsin C propeptide significantly increased the degradation of of intestinal alkaline phosphatase (IAP)
regulation of proteolysis involved in cellular protein catabolic process
Any process that modulates the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:18307834
regulation of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
regulation of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
regulation of peptidolysis during cellular protein catabolic process
GOC:TermGenie
regulation of peptidolysis during cellular protein catabolism
GOC:TermGenie
regulation of proteolysis during cellular protein catabolic process
GOC:TermGenie
regulation of proteolysis during cellular protein catabolism
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
rl
2014-05-22T18:00:51Z
down regulation of peptidolysis involved in cellular protein catabolic process
down regulation of peptidolysis involved in cellular protein catabolism
down regulation of proteolysis involved in cellular protein catabolic process
down-regulation of peptidolysis involved in cellular protein catabolic process
down-regulation of peptidolysis involved in cellular protein catabolism
down-regulation of proteolysis involved in cellular protein catabolic process
downregulation of peptidolysis involved in cellular protein catabolic process
downregulation of peptidolysis involved in cellular protein catabolism
downregulation of proteolysis involved in cellular protein catabolic process
negative regulation of peptidolysis involved in cellular protein catabolic process
negative regulation of peptidolysis involved in cellular protein catabolism
inhibition of peptidolysis involved in cellular protein catabolic process
inhibition of peptidolysis involved in cellular protein catabolism
inhibition of proteolysis involved in cellular protein catabolic process
biological_process
down regulation of peptidolysis during cellular protein catabolic process
down regulation of peptidolysis during cellular protein catabolism
down regulation of proteolysis during cellular protein catabolic process
down regulation of proteolysis during cellular protein catabolism
down-regulation of peptidolysis during cellular protein catabolic process
down-regulation of peptidolysis during cellular protein catabolism
down-regulation of proteolysis during cellular protein catabolic process
down-regulation of proteolysis during cellular protein catabolism
downregulation of peptidolysis during cellular protein catabolic process
downregulation of peptidolysis during cellular protein catabolism
downregulation of proteolysis during cellular protein catabolic process
downregulation of proteolysis during cellular protein catabolism
inhibition of peptidolysis during cellular protein catabolic process
inhibition of peptidolysis during cellular protein catabolism
inhibition of proteolysis during cellular protein catabolic process
inhibition of proteolysis during cellular protein catabolism
negative regulation of peptidolysis during cellular protein catabolic process
negative regulation of peptidolysis during cellular protein catabolism
negative regulation of proteolysis during cellular protein catabolic process
negative regulation of proteolysis during cellular protein catabolism
Overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP).
negative regulation of proteolysis involved in cellular protein catabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:18307834
down regulation of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
down regulation of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
down regulation of proteolysis involved in cellular protein catabolic process
GOC:TermGenie
down-regulation of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
down-regulation of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
down-regulation of proteolysis involved in cellular protein catabolic process
GOC:TermGenie
downregulation of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
downregulation of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
downregulation of proteolysis involved in cellular protein catabolic process
GOC:TermGenie
negative regulation of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
negative regulation of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
inhibition of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
inhibition of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
inhibition of proteolysis involved in cellular protein catabolic process
GOC:TermGenie
down regulation of peptidolysis during cellular protein catabolic process
GOC:TermGenie
down regulation of peptidolysis during cellular protein catabolism
GOC:TermGenie
down regulation of proteolysis during cellular protein catabolic process
GOC:TermGenie
down regulation of proteolysis during cellular protein catabolism
GOC:TermGenie
down-regulation of peptidolysis during cellular protein catabolic process
GOC:TermGenie
down-regulation of peptidolysis during cellular protein catabolism
GOC:TermGenie
down-regulation of proteolysis during cellular protein catabolic process
GOC:TermGenie
down-regulation of proteolysis during cellular protein catabolism
GOC:TermGenie
downregulation of peptidolysis during cellular protein catabolic process
GOC:TermGenie
downregulation of peptidolysis during cellular protein catabolism
GOC:TermGenie
downregulation of proteolysis during cellular protein catabolic process
GOC:TermGenie
downregulation of proteolysis during cellular protein catabolism
GOC:TermGenie
inhibition of peptidolysis during cellular protein catabolic process
GOC:TermGenie
inhibition of peptidolysis during cellular protein catabolism
GOC:TermGenie
inhibition of proteolysis during cellular protein catabolic process
GOC:TermGenie
inhibition of proteolysis during cellular protein catabolism
GOC:TermGenie
negative regulation of peptidolysis during cellular protein catabolic process
GOC:TermGenie
negative regulation of peptidolysis during cellular protein catabolism
GOC:TermGenie
negative regulation of proteolysis during cellular protein catabolic process
GOC:TermGenie
negative regulation of proteolysis during cellular protein catabolism
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
rl
2014-05-22T18:00:57Z
positive regulation of peptidolysis involved in cellular protein catabolic process
positive regulation of peptidolysis involved in cellular protein catabolism
up regulation of peptidolysis involved in cellular protein catabolic process
up regulation of peptidolysis involved in cellular protein catabolism
up regulation of proteolysis involved in cellular protein catabolic process
up-regulation of peptidolysis involved in cellular protein catabolic process
up-regulation of peptidolysis involved in cellular protein catabolism
up-regulation of proteolysis involved in cellular protein catabolic process
upregulation of peptidolysis involved in cellular protein catabolic process
upregulation of peptidolysis involved in cellular protein catabolism
upregulation of proteolysis involved in cellular protein catabolic process
activation of peptidolysis involved in cellular protein catabolic process
activation of peptidolysis involved in cellular protein catabolism
activation of proteolysis involved in cellular protein catabolic process
biological_process
activation of peptidolysis during cellular protein catabolic process
activation of peptidolysis during cellular protein catabolism
activation of proteolysis during cellular protein catabolic process
activation of proteolysis during cellular protein catabolism
positive regulation of peptidolysis during cellular protein catabolic process
positive regulation of peptidolysis during cellular protein catabolism
positive regulation of proteolysis during cellular protein catabolic process
positive regulation of proteolysis during cellular protein catabolism
up regulation of peptidolysis during cellular protein catabolic process
up regulation of peptidolysis during cellular protein catabolism
up regulation of proteolysis during cellular protein catabolic process
up regulation of proteolysis during cellular protein catabolism
up-regulation of peptidolysis during cellular protein catabolic process
up-regulation of peptidolysis during cellular protein catabolism
up-regulation of proteolysis during cellular protein catabolic process
up-regulation of proteolysis during cellular protein catabolism
upregulation of peptidolysis during cellular protein catabolic process
upregulation of peptidolysis during cellular protein catabolism
upregulation of proteolysis during cellular protein catabolic process
upregulation of proteolysis during cellular protein catabolism
overexpression of cathepsin C propeptide significantly increased the degradation of of intestinal alkaline phosphatase (IAP)
positive regulation of proteolysis involved in cellular protein catabolic process
Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:18307834
positive regulation of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
positive regulation of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
up regulation of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
up regulation of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
up regulation of proteolysis involved in cellular protein catabolic process
GOC:TermGenie
up-regulation of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
up-regulation of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
up-regulation of proteolysis involved in cellular protein catabolic process
GOC:TermGenie
upregulation of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
upregulation of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
upregulation of proteolysis involved in cellular protein catabolic process
GOC:TermGenie
activation of peptidolysis involved in cellular protein catabolic process
GOC:TermGenie
activation of peptidolysis involved in cellular protein catabolism
GOC:TermGenie
activation of proteolysis involved in cellular protein catabolic process
GOC:TermGenie
activation of peptidolysis during cellular protein catabolic process
GOC:TermGenie
activation of peptidolysis during cellular protein catabolism
GOC:TermGenie
activation of proteolysis during cellular protein catabolic process
GOC:TermGenie
activation of proteolysis during cellular protein catabolism
GOC:TermGenie
positive regulation of peptidolysis during cellular protein catabolic process
GOC:TermGenie
positive regulation of peptidolysis during cellular protein catabolism
GOC:TermGenie
positive regulation of proteolysis during cellular protein catabolic process
GOC:TermGenie
positive regulation of proteolysis during cellular protein catabolism
GOC:TermGenie
up regulation of peptidolysis during cellular protein catabolic process
GOC:TermGenie
up regulation of peptidolysis during cellular protein catabolism
GOC:TermGenie
up regulation of proteolysis during cellular protein catabolic process
GOC:TermGenie
up regulation of proteolysis during cellular protein catabolism
GOC:TermGenie
up-regulation of peptidolysis during cellular protein catabolic process
GOC:TermGenie
up-regulation of peptidolysis during cellular protein catabolism
GOC:TermGenie
up-regulation of proteolysis during cellular protein catabolic process
GOC:TermGenie
up-regulation of proteolysis during cellular protein catabolism
GOC:TermGenie
upregulation of peptidolysis during cellular protein catabolic process
GOC:TermGenie
upregulation of peptidolysis during cellular protein catabolism
GOC:TermGenie
upregulation of proteolysis during cellular protein catabolic process
GOC:TermGenie
upregulation of proteolysis during cellular protein catabolism
GOC:TermGenie
Any process that modulates the frequency, rate or extent of extracellular matrix organization.
rl
2014-05-23T17:15:41Z
regulation of extracellular matrix organisation
biological_process
regulation of extracellular matrix organization and biogenesis
regulation of extracellular matrix organization
Any process that modulates the frequency, rate or extent of extracellular matrix organization.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:22357537
regulation of extracellular matrix organisation
GOC:TermGenie
regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.
rl
2014-05-23T17:15:47Z
down regulation of extracellular matrix organisation
down regulation of extracellular matrix organization
down-regulation of extracellular matrix organisation
down-regulation of extracellular matrix organization
downregulation of extracellular matrix organisation
downregulation of extracellular matrix organization
negative regulation of extracellular matrix organisation
inhibition of extracellular matrix organisation
inhibition of extracellular matrix organization
biological_process
down regulation of extracellular matrix organization and biogenesis
down-regulation of extracellular matrix organization and biogenesis
downregulation of extracellular matrix organization and biogenesis
inhibition of extracellular matrix organization and biogenesis
negative regulation of extracellular matrix organization and biogenesis
negative regulation of extracellular matrix organization
Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:22357537
down regulation of extracellular matrix organisation
GOC:TermGenie
down regulation of extracellular matrix organization
GOC:TermGenie
down-regulation of extracellular matrix organisation
GOC:TermGenie
down-regulation of extracellular matrix organization
GOC:TermGenie
downregulation of extracellular matrix organisation
GOC:TermGenie
downregulation of extracellular matrix organization
GOC:TermGenie
negative regulation of extracellular matrix organisation
GOC:TermGenie
inhibition of extracellular matrix organisation
GOC:TermGenie
inhibition of extracellular matrix organization
GOC:TermGenie
down regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
down-regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
downregulation of extracellular matrix organization and biogenesis
GOC:TermGenie
inhibition of extracellular matrix organization and biogenesis
GOC:TermGenie
negative regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.
rl
2014-05-23T17:15:53Z
positive regulation of extracellular matrix organisation
up regulation of extracellular matrix organisation
up regulation of extracellular matrix organization
up-regulation of extracellular matrix organisation
up-regulation of extracellular matrix organization
upregulation of extracellular matrix organisation
upregulation of extracellular matrix organization
activation of extracellular matrix organisation
activation of extracellular matrix organization
biological_process
activation of extracellular matrix organization and biogenesis
positive regulation of extracellular matrix organization and biogenesis
up regulation of extracellular matrix organization and biogenesis
up-regulation of extracellular matrix organization and biogenesis
upregulation of extracellular matrix organization and biogenesis
positive regulation of extracellular matrix organization
Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:22357537
positive regulation of extracellular matrix organisation
GOC:TermGenie
up regulation of extracellular matrix organisation
GOC:TermGenie
up regulation of extracellular matrix organization
GOC:TermGenie
up-regulation of extracellular matrix organisation
GOC:TermGenie
up-regulation of extracellular matrix organization
GOC:TermGenie
upregulation of extracellular matrix organisation
GOC:TermGenie
upregulation of extracellular matrix organization
GOC:TermGenie
activation of extracellular matrix organisation
GOC:TermGenie
activation of extracellular matrix organization
GOC:TermGenie
activation of extracellular matrix organization and biogenesis
GOC:TermGenie
positive regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
up regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
up-regulation of extracellular matrix organization and biogenesis
GOC:TermGenie
upregulation of extracellular matrix organization and biogenesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.
tanyaberardini
2009-07-10T10:32:44Z
GO:0090003
GO:1905963
regulation of protein localization in plasma membrane
biological_process
regulation of establishment of protein localisation in plasma membrane
regulation of establishment of protein localization in plasma membrane
regulation of establishment of protein localization to plasma membrane
regulation of protein localisation in plasma membrane
regulation of protein targeting to plasma membrane
regulation of protein-plasma membrane targeting
regulation of protein localization to plasma membrane
Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:11602640
regulation of protein localization in plasma membrane
GOC:TermGenie
regulation of establishment of protein localisation in plasma membrane
GOC:mah
regulation of protein localisation in plasma membrane
GOC:TermGenie
regulation of protein-plasma membrane targeting
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane.
tanyaberardini
2014-05-29T17:10:16Z
GO:0090005
GO:1905964
down regulation of protein localisation in plasma membrane
down regulation of protein localization in plasma membrane
down regulation of protein localization to plasma membrane
down-regulation of protein localisation in plasma membrane
down-regulation of protein localization in plasma membrane
down-regulation of protein localization to plasma membrane
downregulation of protein localisation in plasma membrane
downregulation of protein localization in plasma membrane
downregulation of protein localization to plasma membrane
negative regulation of protein localization in plasma membrane
inhibition of protein localisation in plasma membrane
inhibition of protein localization in plasma membrane
inhibition of protein localization to plasma membrane
inhibition of protein targeting to plasma membrane
inhibition of protein-plasma membrane targeting
biological_process
down regulation of protein targeting to plasma membrane
down regulation of protein-plasma membrane targeting
down-regulation of protein targeting to plasma membrane
down-regulation of protein-plasma membrane targeting
downregulation of protein targeting to plasma membrane
downregulation of protein-plasma membrane targeting
negative regulation of establishment of protein localisation in plasma membrane
negative regulation of establishment of protein localization in plasma membrane
negative regulation of establishment of protein localization to plasma membrane
negative regulation of protein localisation in plasma membrane
negative regulation of protein targeting to plasma membrane
negative regulation of protein-plasma membrane targeting
negative regulation of protein localization to plasma membrane
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:11602640
down regulation of protein localisation in plasma membrane
GOC:TermGenie
down regulation of protein localization in plasma membrane
GOC:TermGenie
down regulation of protein localization to plasma membrane
GOC:TermGenie
down-regulation of protein localisation in plasma membrane
GOC:TermGenie
down-regulation of protein localization in plasma membrane
GOC:TermGenie
down-regulation of protein localization to plasma membrane
GOC:TermGenie
downregulation of protein localisation in plasma membrane
GOC:TermGenie
downregulation of protein localization in plasma membrane
GOC:TermGenie
downregulation of protein localization to plasma membrane
GOC:TermGenie
negative regulation of protein localization in plasma membrane
GOC:TermGenie
inhibition of protein localisation in plasma membrane
GOC:TermGenie
inhibition of protein localization in plasma membrane
GOC:TermGenie
inhibition of protein localization to plasma membrane
GOC:TermGenie
inhibition of protein targeting to plasma membrane
GOC:TermGenie
inhibition of protein-plasma membrane targeting
GOC:TermGenie
down regulation of protein targeting to plasma membrane
GOC:TermGenie
down regulation of protein-plasma membrane targeting
GOC:TermGenie
down-regulation of protein targeting to plasma membrane
GOC:TermGenie
down-regulation of protein-plasma membrane targeting
GOC:TermGenie
downregulation of protein targeting to plasma membrane
GOC:TermGenie
downregulation of protein-plasma membrane targeting
GOC:TermGenie
negative regulation of establishment of protein localisation in plasma membrane
GOC:mah
negative regulation of protein localisation in plasma membrane
GOC:TermGenie
negative regulation of protein-plasma membrane targeting
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.
tanyaberardini
2009-07-10T10:34:17Z
GO:0090004
GO:1905965
positive regulation of protein localisation in plasma membrane
positive regulation of protein localization in plasma membrane
up regulation of protein localisation in plasma membrane
up regulation of protein localization in plasma membrane
up regulation of protein localization to plasma membrane
up-regulation of protein localisation in plasma membrane
up-regulation of protein localization in plasma membrane
up-regulation of protein localization to plasma membrane
upregulation of protein localisation in plasma membrane
upregulation of protein localization in plasma membrane
upregulation of protein localization to plasma membrane
activation of protein localisation in plasma membrane
activation of protein localization in plasma membrane
activation of protein localization to plasma membrane
activation of protein targeting to plasma membrane
activation of protein-plasma membrane targeting
biological_process
positive regulation of establishment of protein localisation in plasma membrane
positive regulation of establishment of protein localization to plasma membrane
positive regulation of protein targeting to plasma membrane
positive regulation of protein-plasma membrane targeting
up regulation of protein targeting to plasma membrane
up regulation of protein-plasma membrane targeting
up-regulation of protein targeting to plasma membrane
up-regulation of protein-plasma membrane targeting
upregulation of protein targeting to plasma membrane
upregulation of protein-plasma membrane targeting
positive regulation of protein localization to plasma membrane
Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:11602640
positive regulation of protein localisation in plasma membrane
GOC:TermGenie
positive regulation of protein localization in plasma membrane
GOC:TermGenie
up regulation of protein localisation in plasma membrane
GOC:TermGenie
up regulation of protein localization in plasma membrane
GOC:TermGenie
up regulation of protein localization to plasma membrane
GOC:TermGenie
up-regulation of protein localisation in plasma membrane
GOC:TermGenie
up-regulation of protein localization in plasma membrane
GOC:TermGenie
up-regulation of protein localization to plasma membrane
GOC:TermGenie
upregulation of protein localisation in plasma membrane
GOC:TermGenie
upregulation of protein localization in plasma membrane
GOC:TermGenie
upregulation of protein localization to plasma membrane
GOC:TermGenie
activation of protein localisation in plasma membrane
GOC:TermGenie
activation of protein localization in plasma membrane
GOC:TermGenie
activation of protein localization to plasma membrane
GOC:TermGenie
activation of protein targeting to plasma membrane
GOC:TermGenie
activation of protein-plasma membrane targeting
GOC:TermGenie
positive regulation of establishment of protein localisation in plasma membrane
GOC:mah
positive regulation of protein-plasma membrane targeting
GOC:TermGenie
up regulation of protein targeting to plasma membrane
GOC:TermGenie
up regulation of protein-plasma membrane targeting
GOC:TermGenie
up-regulation of protein targeting to plasma membrane
GOC:TermGenie
up-regulation of protein-plasma membrane targeting
GOC:TermGenie
upregulation of protein targeting to plasma membrane
GOC:TermGenie
upregulation of protein-plasma membrane targeting
GOC:TermGenie
Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion.
al
2014-06-09T11:53:14Z
regulation of mitochondrial transcription
regulation of transcription from mitochondrial promoter
biological_process
regulation of mitochondrial transcription
Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion.
GOC:TermGenie
GO_REF:0000058
PMID:21357609
regulation of mitochondrial transcription
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion.
al
2014-06-09T11:53:20Z
positive regulation of mitochondrial transcription
positive regulation of transcription from mitochondrial promoter
up regulation of mitochondrial transcription
up regulation of transcription from mitochondrial promoter
up-regulation of mitochondrial transcription
up-regulation of transcription from mitochondrial promoter
upregulation of mitochondrial transcription
upregulation of transcription from mitochondrial promoter
activation of mitochondrial transcription
activation of transcription from mitochondrial promoter
biological_process
positive regulation of mitochondrial transcription
Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion.
GOC:TermGenie
GO_REF:0000058
PMID:21357609
positive regulation of mitochondrial transcription
GOC:TermGenie
up regulation of mitochondrial transcription
GOC:TermGenie
up regulation of transcription from mitochondrial promoter
GOC:TermGenie
up-regulation of mitochondrial transcription
GOC:TermGenie
up-regulation of transcription from mitochondrial promoter
GOC:TermGenie
upregulation of mitochondrial transcription
GOC:TermGenie
upregulation of transcription from mitochondrial promoter
GOC:TermGenie
activation of mitochondrial transcription
GOC:TermGenie
activation of transcription from mitochondrial promoter
GOC:TermGenie
Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.
bf
2014-07-09T08:23:51Z
regulation of mitochondrion degradation
biological_process
regulation of autophagy of mitochondrion
Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.
GOC:PARL
GOC:TermGenie
GOC:autophagy
GOC:bf
GO_REF:0000058
PMID:24600391
regulation of mitochondrion degradation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy.
bf
2014-07-09T08:23:58Z
down regulation of mitochondrial degradation
down regulation of mitochondrion degradation
down-regulation of mitochondrion degradation
down-regulation of mitophagy
downregulation of mitochondrion degradation
inhibition of mitophagy
biological_process
inhibition of mitochondrion degradation
negative regulation of autophagy of mitochondrion
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy.
GOC:PARL
GOC:TermGenie
GOC:autophagy
GOC:bf
GO_REF:0000058
PMID:24600391
down regulation of mitochondrial degradation
GOC:TermGenie
down regulation of mitochondrion degradation
GOC:TermGenie
down-regulation of mitochondrion degradation
GOC:TermGenie
down-regulation of mitophagy
GOC:TermGenie
downregulation of mitochondrion degradation
GOC:TermGenie
inhibition of mitophagy
GOC:TermGenie
inhibition of mitochondrion degradation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion.
bf
2014-07-24T10:17:13Z
regulation of protein import into mitochondrion
regulation of protein targeting to mitochondria
regulation of protein-mitochondrial targeting
biological_process
regulation of mitochondrial protein import
regulation of mitochondrial translocation
regulation of protein targeting to mitochondrion
Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
regulation of protein import into mitochondrion
GOC:TermGenie
regulation of protein targeting to mitochondria
GOC:TermGenie
regulation of protein-mitochondrial targeting
GOC:TermGenie
regulation of mitochondrial protein import
GOC:TermGenie
regulation of mitochondrial translocation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion.
bf
2014-07-24T10:17:19Z
down regulation of protein import into mitochondrion
down regulation of protein targeting to mitochondria
down regulation of protein targeting to mitochondrion
down regulation of protein-mitochondrial targeting
down-regulation of protein import into mitochondrion
down-regulation of protein targeting to mitochondria
down-regulation of protein targeting to mitochondrion
down-regulation of protein-mitochondrial targeting
downregulation of protein import into mitochondrion
downregulation of protein targeting to mitochondria
downregulation of protein targeting to mitochondrion
downregulation of protein-mitochondrial targeting
negative regulation of protein import into mitochondrion
negative regulation of protein targeting to mitochondria
negative regulation of protein-mitochondrial targeting
inhibition of protein import into mitochondrion
inhibition of protein targeting to mitochondria
inhibition of protein targeting to mitochondrion
inhibition of protein-mitochondrial targeting
biological_process
down regulation of mitochondrial protein import
down regulation of mitochondrial translocation
down-regulation of mitochondrial protein import
down-regulation of mitochondrial translocation
downregulation of mitochondrial protein import
downregulation of mitochondrial translocation
inhibition of mitochondrial protein import
inhibition of mitochondrial translocation
negative regulation of mitochondrial protein import
negative regulation of mitochondrial translocation
negative regulation of protein targeting to mitochondrion
Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
PMID:21370995
down regulation of protein import into mitochondrion
GOC:TermGenie
down regulation of protein targeting to mitochondria
GOC:TermGenie
down regulation of protein targeting to mitochondrion
GOC:TermGenie
down regulation of protein-mitochondrial targeting
GOC:TermGenie
down-regulation of protein import into mitochondrion
GOC:TermGenie
down-regulation of protein targeting to mitochondria
GOC:TermGenie
down-regulation of protein targeting to mitochondrion
GOC:TermGenie
down-regulation of protein-mitochondrial targeting
GOC:TermGenie
downregulation of protein import into mitochondrion
GOC:TermGenie
downregulation of protein targeting to mitochondria
GOC:TermGenie
downregulation of protein targeting to mitochondrion
GOC:TermGenie
downregulation of protein-mitochondrial targeting
GOC:TermGenie
negative regulation of protein import into mitochondrion
GOC:TermGenie
negative regulation of protein targeting to mitochondria
GOC:TermGenie
negative regulation of protein-mitochondrial targeting
GOC:TermGenie
inhibition of protein import into mitochondrion
GOC:TermGenie
inhibition of protein targeting to mitochondria
GOC:TermGenie
inhibition of protein targeting to mitochondrion
GOC:TermGenie
inhibition of protein-mitochondrial targeting
GOC:TermGenie
down regulation of mitochondrial protein import
GOC:TermGenie
down regulation of mitochondrial translocation
GOC:TermGenie
down-regulation of mitochondrial protein import
GOC:TermGenie
down-regulation of mitochondrial translocation
GOC:TermGenie
downregulation of mitochondrial protein import
GOC:TermGenie
downregulation of mitochondrial translocation
GOC:TermGenie
inhibition of mitochondrial protein import
GOC:TermGenie
inhibition of mitochondrial translocation
GOC:TermGenie
negative regulation of mitochondrial protein import
GOC:TermGenie
negative regulation of mitochondrial translocation
GOC:TermGenie
A protein complex which is capable of phosphatase activity.
bhm
2014-08-13T10:25:32Z
cellular_component
An example of this is PTEN in human (P60484) in PMID:24766807 (inferred from direct assay).
phosphatase complex
A protein complex which is capable of phosphatase activity.
GOC:TermGenie
GOC:bhm
GO_REF:0000088
PMID:24766807
Any process that modulates the frequency, rate or extent of mRNA metabolic process.
vw
2014-08-18T11:52:26Z
regulation of mRNA metabolism
biological_process
regulation of mRNA metabolic process
Any process that modulates the frequency, rate or extent of mRNA metabolic process.
GOC:TermGenie
GOC:vw
GO_REF:0000058
regulation of mRNA metabolism
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process.
vw
2014-08-18T11:52:34Z
down regulation of mRNA metabolic process
down regulation of mRNA metabolism
down-regulation of mRNA metabolic process
down-regulation of mRNA metabolism
downregulation of mRNA metabolic process
downregulation of mRNA metabolism
negative regulation of mRNA metabolism
inhibition of mRNA metabolic process
inhibition of mRNA metabolism
biological_process
negative regulation of mRNA metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process.
GOC:TermGenie
GOC:vw
GO_REF:0000058
down regulation of mRNA metabolic process
GOC:TermGenie
down regulation of mRNA metabolism
GOC:TermGenie
down-regulation of mRNA metabolic process
GOC:TermGenie
down-regulation of mRNA metabolism
GOC:TermGenie
downregulation of mRNA metabolic process
GOC:TermGenie
downregulation of mRNA metabolism
GOC:TermGenie
negative regulation of mRNA metabolism
GOC:TermGenie
inhibition of mRNA metabolic process
GOC:TermGenie
inhibition of mRNA metabolism
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.
vw
2014-08-18T11:52:42Z
positive regulation of mRNA metabolism
up regulation of mRNA metabolic process
up regulation of mRNA metabolism
up-regulation of mRNA metabolic process
up-regulation of mRNA metabolism
upregulation of mRNA metabolic process
upregulation of mRNA metabolism
activation of mRNA metabolic process
activation of mRNA metabolism
biological_process
positive regulation of mRNA metabolic process
Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.
GOC:TermGenie
GOC:vw
GO_REF:0000058
positive regulation of mRNA metabolism
GOC:TermGenie
up regulation of mRNA metabolic process
GOC:TermGenie
up regulation of mRNA metabolism
GOC:TermGenie
up-regulation of mRNA metabolic process
GOC:TermGenie
up-regulation of mRNA metabolism
GOC:TermGenie
upregulation of mRNA metabolic process
GOC:TermGenie
upregulation of mRNA metabolism
GOC:TermGenie
activation of mRNA metabolic process
GOC:TermGenie
activation of mRNA metabolism
GOC:TermGenie
Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process.
vw
2014-08-18T12:57:34Z
biological_process
regulation of nitrogen cycle metabolic process
Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process.
GOC:TermGenie
GOC:vw
GO_REF:0000058
Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process.
vw
2014-08-18T12:57:42Z
down regulation of nitrogen cycle metabolic process
down-regulation of nitrogen cycle metabolic process
downregulation of nitrogen cycle metabolic process
inhibition of nitrogen cycle metabolic process
biological_process
negative regulation of nitrogen cycle metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process.
GOC:TermGenie
GOC:vw
GO_REF:0000058
down regulation of nitrogen cycle metabolic process
GOC:TermGenie
down-regulation of nitrogen cycle metabolic process
GOC:TermGenie
downregulation of nitrogen cycle metabolic process
GOC:TermGenie
inhibition of nitrogen cycle metabolic process
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process.
vw
2014-08-18T12:57:50Z
up regulation of nitrogen cycle metabolic process
up-regulation of nitrogen cycle metabolic process
upregulation of nitrogen cycle metabolic process
activation of nitrogen cycle metabolic process
biological_process
positive regulation of nitrogen cycle metabolic process
Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process.
GOC:TermGenie
GOC:vw
GO_REF:0000058
up regulation of nitrogen cycle metabolic process
GOC:TermGenie
up-regulation of nitrogen cycle metabolic process
GOC:TermGenie
upregulation of nitrogen cycle metabolic process
GOC:TermGenie
activation of nitrogen cycle metabolic process
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein maturation.
vw
2014-08-18T12:59:07Z
biological_process
regulation of protein maturation
Any process that modulates the frequency, rate or extent of protein maturation.
GOC:TermGenie
GOC:vw
GO_REF:0000058
Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.
vw
2014-08-18T12:59:15Z
down regulation of protein maturation
down-regulation of protein maturation
downregulation of protein maturation
inhibition of protein maturation
biological_process
negative regulation of protein maturation
Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.
GOC:TermGenie
GOC:vw
GO_REF:0000058
down regulation of protein maturation
GOC:TermGenie
down-regulation of protein maturation
GOC:TermGenie
downregulation of protein maturation
GOC:TermGenie
inhibition of protein maturation
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein maturation.
vw
2014-08-18T12:59:23Z
up regulation of protein maturation
up-regulation of protein maturation
upregulation of protein maturation
activation of protein maturation
biological_process
positive regulation of protein maturation
Any process that activates or increases the frequency, rate or extent of protein maturation.
GOC:TermGenie
GOC:vw
GO_REF:0000058
up regulation of protein maturation
GOC:TermGenie
up-regulation of protein maturation
GOC:TermGenie
upregulation of protein maturation
GOC:TermGenie
activation of protein maturation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of tRNA metabolic process.
vw
2014-08-18T13:08:50Z
regulation of tRNA metabolism
biological_process
regulation of tRNA metabolic process
Any process that modulates the frequency, rate or extent of tRNA metabolic process.
GOC:TermGenie
GOC:vw
GO_REF:0000058
regulation of tRNA metabolism
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process.
vw
2014-08-18T13:08:58Z
down regulation of tRNA metabolic process
down regulation of tRNA metabolism
down-regulation of tRNA metabolic process
down-regulation of tRNA metabolism
downregulation of tRNA metabolic process
downregulation of tRNA metabolism
negative regulation of tRNA metabolism
inhibition of tRNA metabolic process
inhibition of tRNA metabolism
biological_process
negative regulation of tRNA metabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process.
GOC:TermGenie
GOC:vw
GO_REF:0000058
down regulation of tRNA metabolic process
GOC:TermGenie
down regulation of tRNA metabolism
GOC:TermGenie
down-regulation of tRNA metabolic process
GOC:TermGenie
down-regulation of tRNA metabolism
GOC:TermGenie
downregulation of tRNA metabolic process
GOC:TermGenie
downregulation of tRNA metabolism
GOC:TermGenie
negative regulation of tRNA metabolism
GOC:TermGenie
inhibition of tRNA metabolic process
GOC:TermGenie
inhibition of tRNA metabolism
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of tRNA metabolic process.
vw
2014-08-18T13:09:06Z
positive regulation of tRNA metabolism
up regulation of tRNA metabolic process
up regulation of tRNA metabolism
up-regulation of tRNA metabolic process
up-regulation of tRNA metabolism
upregulation of tRNA metabolic process
upregulation of tRNA metabolism
activation of tRNA metabolic process
activation of tRNA metabolism
biological_process
positive regulation of tRNA metabolic process
Any process that activates or increases the frequency, rate or extent of tRNA metabolic process.
GOC:TermGenie
GOC:vw
GO_REF:0000058
positive regulation of tRNA metabolism
GOC:TermGenie
up regulation of tRNA metabolic process
GOC:TermGenie
up regulation of tRNA metabolism
GOC:TermGenie
up-regulation of tRNA metabolic process
GOC:TermGenie
up-regulation of tRNA metabolism
GOC:TermGenie
upregulation of tRNA metabolic process
GOC:TermGenie
upregulation of tRNA metabolism
GOC:TermGenie
activation of tRNA metabolic process
GOC:TermGenie
activation of tRNA metabolism
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein folding.
vw
2014-08-18T13:14:34Z
regulation of alpha-tubulin folding
regulation of beta-tubulin folding
regulation of chaperonin-mediated tubulin folding
biological_process
regulation of chaperone activity
regulation of chaperonin ATPase activity
regulation of co-chaperone activity
regulation of co-chaperonin activity
regulation of glycoprotein-specific chaperone activity
regulation of non-chaperonin molecular chaperone ATPase activity
regulation of protein complex assembly, multichaperone pathway
regulation of protein folding
Any process that modulates the frequency, rate or extent of protein folding.
GOC:TermGenie
GOC:vw
GO_REF:0000058
regulation of alpha-tubulin folding
GOC:TermGenie
regulation of beta-tubulin folding
GOC:TermGenie
regulation of chaperonin-mediated tubulin folding
GOC:TermGenie
regulation of chaperone activity
GOC:TermGenie
regulation of chaperonin ATPase activity
GOC:TermGenie
regulation of co-chaperone activity
GOC:TermGenie
regulation of co-chaperonin activity
GOC:TermGenie
regulation of glycoprotein-specific chaperone activity
GOC:TermGenie
regulation of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
regulation of protein complex assembly, multichaperone pathway
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein folding.
vw
2014-08-18T13:14:42Z
down regulation of protein folding
down-regulation of protein folding
downregulation of protein folding
down regulation of alpha-tubulin folding
down regulation of beta-tubulin folding
down regulation of chaperonin-mediated tubulin folding
down-regulation of alpha-tubulin folding
down-regulation of beta-tubulin folding
down-regulation of chaperonin-mediated tubulin folding
downregulation of alpha-tubulin folding
downregulation of beta-tubulin folding
downregulation of chaperonin-mediated tubulin folding
inhibition of alpha-tubulin folding
inhibition of beta-tubulin folding
inhibition of chaperonin-mediated tubulin folding
inhibition of protein folding
negative regulation of alpha-tubulin folding
negative regulation of beta-tubulin folding
negative regulation of chaperonin-mediated tubulin folding
biological_process
down regulation of chaperone activity
down regulation of chaperonin ATPase activity
down regulation of co-chaperone activity
down regulation of co-chaperonin activity
down regulation of glycoprotein-specific chaperone activity
down regulation of non-chaperonin molecular chaperone ATPase activity
down regulation of protein complex assembly, multichaperone pathway
down-regulation of chaperone activity
down-regulation of chaperonin ATPase activity
down-regulation of co-chaperone activity
down-regulation of co-chaperonin activity
down-regulation of glycoprotein-specific chaperone activity
down-regulation of non-chaperonin molecular chaperone ATPase activity
down-regulation of protein complex assembly, multichaperone pathway
downregulation of chaperone activity
downregulation of chaperonin ATPase activity
downregulation of co-chaperone activity
downregulation of co-chaperonin activity
downregulation of glycoprotein-specific chaperone activity
downregulation of non-chaperonin molecular chaperone ATPase activity
downregulation of protein complex assembly, multichaperone pathway
inhibition of chaperone activity
inhibition of chaperonin ATPase activity
inhibition of co-chaperone activity
inhibition of co-chaperonin activity
inhibition of glycoprotein-specific chaperone activity
inhibition of non-chaperonin molecular chaperone ATPase activity
inhibition of protein complex assembly, multichaperone pathway
negative regulation of chaperone activity
negative regulation of chaperonin ATPase activity
negative regulation of co-chaperone activity
negative regulation of co-chaperonin activity
negative regulation of glycoprotein-specific chaperone activity
negative regulation of non-chaperonin molecular chaperone ATPase activity
negative regulation of protein complex assembly, multichaperone pathway
negative regulation of protein folding
Any process that stops, prevents or reduces the frequency, rate or extent of protein folding.
GOC:TermGenie
GOC:vw
GO_REF:0000058
down regulation of protein folding
GOC:TermGenie
down-regulation of protein folding
GOC:TermGenie
downregulation of protein folding
GOC:TermGenie
down regulation of alpha-tubulin folding
GOC:TermGenie
down regulation of beta-tubulin folding
GOC:TermGenie
down regulation of chaperonin-mediated tubulin folding
GOC:TermGenie
down-regulation of alpha-tubulin folding
GOC:TermGenie
down-regulation of beta-tubulin folding
GOC:TermGenie
down-regulation of chaperonin-mediated tubulin folding
GOC:TermGenie
downregulation of alpha-tubulin folding
GOC:TermGenie
downregulation of beta-tubulin folding
GOC:TermGenie
downregulation of chaperonin-mediated tubulin folding
GOC:TermGenie
inhibition of alpha-tubulin folding
GOC:TermGenie
inhibition of beta-tubulin folding
GOC:TermGenie
inhibition of chaperonin-mediated tubulin folding
GOC:TermGenie
inhibition of protein folding
GOC:TermGenie
negative regulation of alpha-tubulin folding
GOC:TermGenie
negative regulation of beta-tubulin folding
GOC:TermGenie
negative regulation of chaperonin-mediated tubulin folding
GOC:TermGenie
down regulation of chaperone activity
GOC:TermGenie
down regulation of chaperonin ATPase activity
GOC:TermGenie
down regulation of co-chaperone activity
GOC:TermGenie
down regulation of co-chaperonin activity
GOC:TermGenie
down regulation of glycoprotein-specific chaperone activity
GOC:TermGenie
down regulation of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
down regulation of protein complex assembly, multichaperone pathway
GOC:TermGenie
down-regulation of chaperone activity
GOC:TermGenie
down-regulation of chaperonin ATPase activity
GOC:TermGenie
down-regulation of co-chaperone activity
GOC:TermGenie
down-regulation of co-chaperonin activity
GOC:TermGenie
down-regulation of glycoprotein-specific chaperone activity
GOC:TermGenie
down-regulation of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
down-regulation of protein complex assembly, multichaperone pathway
GOC:TermGenie
downregulation of chaperone activity
GOC:TermGenie
downregulation of chaperonin ATPase activity
GOC:TermGenie
downregulation of co-chaperone activity
GOC:TermGenie
downregulation of co-chaperonin activity
GOC:TermGenie
downregulation of glycoprotein-specific chaperone activity
GOC:TermGenie
downregulation of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
downregulation of protein complex assembly, multichaperone pathway
GOC:TermGenie
inhibition of chaperone activity
GOC:TermGenie
inhibition of chaperonin ATPase activity
GOC:TermGenie
inhibition of co-chaperone activity
GOC:TermGenie
inhibition of co-chaperonin activity
GOC:TermGenie
inhibition of glycoprotein-specific chaperone activity
GOC:TermGenie
inhibition of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
inhibition of protein complex assembly, multichaperone pathway
GOC:TermGenie
negative regulation of chaperone activity
GOC:TermGenie
negative regulation of chaperonin ATPase activity
GOC:TermGenie
negative regulation of co-chaperone activity
GOC:TermGenie
negative regulation of co-chaperonin activity
GOC:TermGenie
negative regulation of glycoprotein-specific chaperone activity
GOC:TermGenie
negative regulation of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
negative regulation of protein complex assembly, multichaperone pathway
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein folding.
vw
2014-08-18T13:14:50Z
up regulation of protein folding
up-regulation of protein folding
upregulation of protein folding
activation of alpha-tubulin folding
activation of beta-tubulin folding
activation of chaperonin-mediated tubulin folding
activation of protein folding
positive regulation of alpha-tubulin folding
positive regulation of beta-tubulin folding
positive regulation of chaperonin-mediated tubulin folding
up regulation of alpha-tubulin folding
up regulation of beta-tubulin folding
up regulation of chaperonin-mediated tubulin folding
up-regulation of alpha-tubulin folding
up-regulation of beta-tubulin folding
up-regulation of chaperonin-mediated tubulin folding
upregulation of alpha-tubulin folding
upregulation of beta-tubulin folding
upregulation of chaperonin-mediated tubulin folding
biological_process
activation of chaperone activity
activation of chaperonin ATPase activity
activation of co-chaperone activity
activation of co-chaperonin activity
activation of glycoprotein-specific chaperone activity
activation of non-chaperonin molecular chaperone ATPase activity
activation of protein complex assembly, multichaperone pathway
positive regulation of chaperone activity
positive regulation of chaperonin ATPase activity
positive regulation of co-chaperone activity
positive regulation of co-chaperonin activity
positive regulation of glycoprotein-specific chaperone activity
positive regulation of non-chaperonin molecular chaperone ATPase activity
positive regulation of protein complex assembly, multichaperone pathway
up regulation of chaperone activity
up regulation of chaperonin ATPase activity
up regulation of co-chaperone activity
up regulation of co-chaperonin activity
up regulation of glycoprotein-specific chaperone activity
up regulation of non-chaperonin molecular chaperone ATPase activity
up regulation of protein complex assembly, multichaperone pathway
up-regulation of chaperone activity
up-regulation of chaperonin ATPase activity
up-regulation of co-chaperone activity
up-regulation of co-chaperonin activity
up-regulation of glycoprotein-specific chaperone activity
up-regulation of non-chaperonin molecular chaperone ATPase activity
up-regulation of protein complex assembly, multichaperone pathway
upregulation of chaperone activity
upregulation of chaperonin ATPase activity
upregulation of co-chaperone activity
upregulation of co-chaperonin activity
upregulation of glycoprotein-specific chaperone activity
upregulation of non-chaperonin molecular chaperone ATPase activity
upregulation of protein complex assembly, multichaperone pathway
positive regulation of protein folding
Any process that activates or increases the frequency, rate or extent of protein folding.
GOC:TermGenie
GOC:vw
GO_REF:0000058
up regulation of protein folding
GOC:TermGenie
up-regulation of protein folding
GOC:TermGenie
upregulation of protein folding
GOC:TermGenie
activation of alpha-tubulin folding
GOC:TermGenie
activation of beta-tubulin folding
GOC:TermGenie
activation of chaperonin-mediated tubulin folding
GOC:TermGenie
activation of protein folding
GOC:TermGenie
positive regulation of alpha-tubulin folding
GOC:TermGenie
positive regulation of beta-tubulin folding
GOC:TermGenie
positive regulation of chaperonin-mediated tubulin folding
GOC:TermGenie
up regulation of alpha-tubulin folding
GOC:TermGenie
up regulation of beta-tubulin folding
GOC:TermGenie
up regulation of chaperonin-mediated tubulin folding
GOC:TermGenie
up-regulation of alpha-tubulin folding
GOC:TermGenie
up-regulation of beta-tubulin folding
GOC:TermGenie
up-regulation of chaperonin-mediated tubulin folding
GOC:TermGenie
upregulation of alpha-tubulin folding
GOC:TermGenie
upregulation of beta-tubulin folding
GOC:TermGenie
upregulation of chaperonin-mediated tubulin folding
GOC:TermGenie
activation of chaperone activity
GOC:TermGenie
activation of chaperonin ATPase activity
GOC:TermGenie
activation of co-chaperone activity
GOC:TermGenie
activation of co-chaperonin activity
GOC:TermGenie
activation of glycoprotein-specific chaperone activity
GOC:TermGenie
activation of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
activation of protein complex assembly, multichaperone pathway
GOC:TermGenie
positive regulation of chaperone activity
GOC:TermGenie
positive regulation of chaperonin ATPase activity
GOC:TermGenie
positive regulation of co-chaperone activity
GOC:TermGenie
positive regulation of co-chaperonin activity
GOC:TermGenie
positive regulation of glycoprotein-specific chaperone activity
GOC:TermGenie
positive regulation of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
positive regulation of protein complex assembly, multichaperone pathway
GOC:TermGenie
up regulation of chaperone activity
GOC:TermGenie
up regulation of chaperonin ATPase activity
GOC:TermGenie
up regulation of co-chaperone activity
GOC:TermGenie
up regulation of co-chaperonin activity
GOC:TermGenie
up regulation of glycoprotein-specific chaperone activity
GOC:TermGenie
up regulation of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
up regulation of protein complex assembly, multichaperone pathway
GOC:TermGenie
up-regulation of chaperone activity
GOC:TermGenie
up-regulation of chaperonin ATPase activity
GOC:TermGenie
up-regulation of co-chaperone activity
GOC:TermGenie
up-regulation of co-chaperonin activity
GOC:TermGenie
up-regulation of glycoprotein-specific chaperone activity
GOC:TermGenie
up-regulation of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
up-regulation of protein complex assembly, multichaperone pathway
GOC:TermGenie
upregulation of chaperone activity
GOC:TermGenie
upregulation of chaperonin ATPase activity
GOC:TermGenie
upregulation of co-chaperone activity
GOC:TermGenie
upregulation of co-chaperonin activity
GOC:TermGenie
upregulation of glycoprotein-specific chaperone activity
GOC:TermGenie
upregulation of non-chaperonin molecular chaperone ATPase activity
GOC:TermGenie
upregulation of protein complex assembly, multichaperone pathway
GOC:TermGenie
Any process that modulates the frequency, rate or extent of vacuolar transport.
vw
2014-08-18T13:16:04Z
biological_process
regulation of vacuolar transport
Any process that modulates the frequency, rate or extent of vacuolar transport.
GOC:TermGenie
GOC:vw
GO_REF:0000058
Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport.
vw
2014-08-18T13:16:11Z
down regulation of vacuolar transport
down-regulation of vacuolar transport
downregulation of vacuolar transport
inhibition of vacuolar transport
biological_process
negative regulation of vacuolar transport
Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport.
GOC:TermGenie
GOC:vw
GO_REF:0000058
down regulation of vacuolar transport
GOC:TermGenie
down-regulation of vacuolar transport
GOC:TermGenie
downregulation of vacuolar transport
GOC:TermGenie
inhibition of vacuolar transport
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of vacuolar transport.
vw
2014-08-18T13:16:19Z
up regulation of vacuolar transport
up-regulation of vacuolar transport
upregulation of vacuolar transport
activation of vacuolar transport
biological_process
positive regulation of vacuolar transport
Any process that activates or increases the frequency, rate or extent of vacuolar transport.
GOC:TermGenie
GOC:vw
GO_REF:0000058
up regulation of vacuolar transport
GOC:TermGenie
up-regulation of vacuolar transport
GOC:TermGenie
upregulation of vacuolar transport
GOC:TermGenie
activation of vacuolar transport
GOC:TermGenie
Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis.
vw
2014-08-18T13:20:50Z
regulation of cell wall organisation or biogenesis
regulation of cell wall organization or biogenesis at cellular level
regulation of cellular cell wall organisation or biogenesis
regulation of cellular cell wall organization or biogenesis
biological_process
regulation of cell wall organization or biogenesis
Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis.
GOC:TermGenie
GOC:vw
GO_REF:0000058
regulation of cell wall organisation or biogenesis
GOC:TermGenie
regulation of cell wall organization or biogenesis at cellular level
GOC:TermGenie
regulation of cellular cell wall organisation or biogenesis
GOC:TermGenie
regulation of cellular cell wall organization or biogenesis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis.
vw
2014-08-18T13:20:58Z
down regulation of cell wall organisation or biogenesis
down regulation of cell wall organization or biogenesis
down regulation of cell wall organization or biogenesis at cellular level
down regulation of cellular cell wall organisation or biogenesis
down regulation of cellular cell wall organization or biogenesis
down-regulation of cell wall organisation or biogenesis
down-regulation of cell wall organization or biogenesis
down-regulation of cell wall organization or biogenesis at cellular level
down-regulation of cellular cell wall organisation or biogenesis
down-regulation of cellular cell wall organization or biogenesis
downregulation of cell wall organisation or biogenesis
downregulation of cell wall organization or biogenesis
downregulation of cell wall organization or biogenesis at cellular level
downregulation of cellular cell wall organisation or biogenesis
downregulation of cellular cell wall organization or biogenesis
negative regulation of cell wall organisation or biogenesis
negative regulation of cell wall organization or biogenesis at cellular level
negative regulation of cellular cell wall organisation or biogenesis
negative regulation of cellular cell wall organization or biogenesis
inhibition of cell wall organisation or biogenesis
inhibition of cell wall organization or biogenesis
inhibition of cell wall organization or biogenesis at cellular level
inhibition of cellular cell wall organisation or biogenesis
inhibition of cellular cell wall organization or biogenesis
biological_process
negative regulation of cell wall organization or biogenesis
Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis.
GOC:TermGenie
GOC:vw
GO_REF:0000058
down regulation of cell wall organisation or biogenesis
GOC:TermGenie
down regulation of cell wall organization or biogenesis
GOC:TermGenie
down regulation of cell wall organization or biogenesis at cellular level
GOC:TermGenie
down regulation of cellular cell wall organisation or biogenesis
GOC:TermGenie
down regulation of cellular cell wall organization or biogenesis
GOC:TermGenie
down-regulation of cell wall organisation or biogenesis
GOC:TermGenie
down-regulation of cell wall organization or biogenesis
GOC:TermGenie
down-regulation of cell wall organization or biogenesis at cellular level
GOC:TermGenie
down-regulation of cellular cell wall organisation or biogenesis
GOC:TermGenie
down-regulation of cellular cell wall organization or biogenesis
GOC:TermGenie
downregulation of cell wall organisation or biogenesis
GOC:TermGenie
downregulation of cell wall organization or biogenesis
GOC:TermGenie
downregulation of cell wall organization or biogenesis at cellular level
GOC:TermGenie
downregulation of cellular cell wall organisation or biogenesis
GOC:TermGenie
downregulation of cellular cell wall organization or biogenesis
GOC:TermGenie
negative regulation of cell wall organisation or biogenesis
GOC:TermGenie
negative regulation of cell wall organization or biogenesis at cellular level
GOC:TermGenie
negative regulation of cellular cell wall organisation or biogenesis
GOC:TermGenie
negative regulation of cellular cell wall organization or biogenesis
GOC:TermGenie
inhibition of cell wall organisation or biogenesis
GOC:TermGenie
inhibition of cell wall organization or biogenesis
GOC:TermGenie
inhibition of cell wall organization or biogenesis at cellular level
GOC:TermGenie
inhibition of cellular cell wall organisation or biogenesis
GOC:TermGenie
inhibition of cellular cell wall organization or biogenesis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis.
vw
2014-08-18T13:21:06Z
positive regulation of cell wall organisation or biogenesis
positive regulation of cell wall organization or biogenesis at cellular level
positive regulation of cellular cell wall organisation or biogenesis
positive regulation of cellular cell wall organization or biogenesis
up regulation of cell wall organisation or biogenesis
up regulation of cell wall organization or biogenesis
up regulation of cell wall organization or biogenesis at cellular level
up regulation of cellular cell wall organisation or biogenesis
up regulation of cellular cell wall organization or biogenesis
up-regulation of cell wall organisation or biogenesis
up-regulation of cell wall organization or biogenesis
up-regulation of cell wall organization or biogenesis at cellular level
up-regulation of cellular cell wall organisation or biogenesis
up-regulation of cellular cell wall organization or biogenesis
upregulation of cell wall organisation or biogenesis
upregulation of cell wall organization or biogenesis
upregulation of cell wall organization or biogenesis at cellular level
upregulation of cellular cell wall organisation or biogenesis
upregulation of cellular cell wall organization or biogenesis
activation of cell wall organisation or biogenesis
activation of cell wall organization or biogenesis
activation of cell wall organization or biogenesis at cellular level
activation of cellular cell wall organisation or biogenesis
activation of cellular cell wall organization or biogenesis
biological_process
positive regulation of cell wall organization or biogenesis
Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis.
GOC:TermGenie
GOC:vw
GO_REF:0000058
positive regulation of cell wall organisation or biogenesis
GOC:TermGenie
positive regulation of cell wall organization or biogenesis at cellular level
GOC:TermGenie
positive regulation of cellular cell wall organisation or biogenesis
GOC:TermGenie
positive regulation of cellular cell wall organization or biogenesis
GOC:TermGenie
up regulation of cell wall organisation or biogenesis
GOC:TermGenie
up regulation of cell wall organization or biogenesis
GOC:TermGenie
up regulation of cell wall organization or biogenesis at cellular level
GOC:TermGenie
up regulation of cellular cell wall organisation or biogenesis
GOC:TermGenie
up regulation of cellular cell wall organization or biogenesis
GOC:TermGenie
up-regulation of cell wall organisation or biogenesis
GOC:TermGenie
up-regulation of cell wall organization or biogenesis
GOC:TermGenie
up-regulation of cell wall organization or biogenesis at cellular level
GOC:TermGenie
up-regulation of cellular cell wall organisation or biogenesis
GOC:TermGenie
up-regulation of cellular cell wall organization or biogenesis
GOC:TermGenie
upregulation of cell wall organisation or biogenesis
GOC:TermGenie
upregulation of cell wall organization or biogenesis
GOC:TermGenie
upregulation of cell wall organization or biogenesis at cellular level
GOC:TermGenie
upregulation of cellular cell wall organisation or biogenesis
GOC:TermGenie
upregulation of cellular cell wall organization or biogenesis
GOC:TermGenie
activation of cell wall organisation or biogenesis
GOC:TermGenie
activation of cell wall organization or biogenesis
GOC:TermGenie
activation of cell wall organization or biogenesis at cellular level
GOC:TermGenie
activation of cellular cell wall organisation or biogenesis
GOC:TermGenie
activation of cellular cell wall organization or biogenesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of nucleus organization.
hjd
2014-08-20T19:36:16Z
regulation of nuclear organisation
regulation of nuclear organization
biological_process
regulation of nuclear morphology
regulation of nuclear organization and biogenesis
regulation of nucleus organization and biogenesis
regulation of nucleus organization
Any process that modulates the frequency, rate or extent of nucleus organization.
GOC:TermGenie
GO_REF:0000058
PMID:16943282
regulation of nuclear organisation
GOC:TermGenie
regulation of nuclear organization
GOC:TermGenie
regulation of nuclear morphology
GOC:TermGenie
regulation of nuclear organization and biogenesis
GOC:TermGenie
regulation of nucleus organization and biogenesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of Golgi organization.
als
2014-08-21T10:22:22Z
regulation of Golgi organisation
biological_process
regulation of Golgi organization and biogenesis
regulation of Golgi organization
Any process that modulates the frequency, rate or extent of Golgi organization.
GOC:TermGenie
GOC:als
GO_REF:0000058
PMID:17562788
regulation of Golgi organisation
GOC:TermGenie
regulation of Golgi organization and biogenesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of cellular protein catabolic process.
kmv
2014-08-21T15:05:45Z
GO:2000598
regulation of cellular protein breakdown
regulation of cellular protein catabolism
regulation of cellular protein degradation
regulation of cyclin breakdown
regulation of cyclin catabolic process
regulation of cyclin catabolism
regulation of cyclin degradation
regulation of degradation of cyclin
biological_process
regulation of cellular protein catabolic process
Any process that modulates the frequency, rate or extent of cellular protein catabolic process.
GOC:TermGenie
GOC:kmv
GOC:obol
GO_REF:0000058
PMID:24785082
regulation of cellular protein breakdown
GOC:TermGenie
regulation of cellular protein catabolism
GOC:TermGenie
regulation of cellular protein degradation
GOC:TermGenie
regulation of cyclin breakdown
GOC:obol
regulation of cyclin catabolism
GOC:obol
regulation of cyclin degradation
GOC:obol
regulation of degradation of cyclin
GOC:obol
Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process.
kmv
2014-08-21T15:05:53Z
GO:2000599
down regulation of cellular protein breakdown
down regulation of cellular protein catabolic process
down regulation of cellular protein catabolism
down regulation of cellular protein degradation
down-regulation of cellular protein breakdown
down-regulation of cellular protein catabolic process
down-regulation of cellular protein catabolism
down-regulation of cellular protein degradation
downregulation of cellular protein breakdown
downregulation of cellular protein catabolic process
downregulation of cellular protein catabolism
downregulation of cellular protein degradation
negative regulation of cellular protein breakdown
negative regulation of cellular protein catabolism
negative regulation of cellular protein degradation
inhibition of cellular protein breakdown
inhibition of cellular protein catabolic process
inhibition of cellular protein catabolism
inhibition of cellular protein degradation
negative regulation of cyclin breakdown
negative regulation of cyclin catabolic process
negative regulation of cyclin catabolism
negative regulation of cyclin degradation
negative regulation of degradation of cyclin
biological_process
negative regulation of cellular protein catabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process.
GOC:TermGenie
GOC:kmv
GOC:obol
GO_REF:0000058
PMID:24785082
down regulation of cellular protein breakdown
GOC:TermGenie
down regulation of cellular protein catabolic process
GOC:TermGenie
down regulation of cellular protein catabolism
GOC:TermGenie
down regulation of cellular protein degradation
GOC:TermGenie
down-regulation of cellular protein breakdown
GOC:TermGenie
down-regulation of cellular protein catabolic process
GOC:TermGenie
down-regulation of cellular protein catabolism
GOC:TermGenie
down-regulation of cellular protein degradation
GOC:TermGenie
downregulation of cellular protein breakdown
GOC:TermGenie
downregulation of cellular protein catabolic process
GOC:TermGenie
downregulation of cellular protein catabolism
GOC:TermGenie
downregulation of cellular protein degradation
GOC:TermGenie
negative regulation of cellular protein breakdown
GOC:TermGenie
negative regulation of cellular protein catabolism
GOC:TermGenie
negative regulation of cellular protein degradation
GOC:TermGenie
inhibition of cellular protein breakdown
GOC:TermGenie
inhibition of cellular protein catabolic process
GOC:TermGenie
inhibition of cellular protein catabolism
GOC:TermGenie
inhibition of cellular protein degradation
GOC:TermGenie
negative regulation of cyclin breakdown
GOC:obol
negative regulation of cyclin catabolism
GOC:obol
negative regulation of cyclin degradation
GOC:obol
negative regulation of degradation of cyclin
GOC:obol
Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process.
kmv
2014-08-21T15:06:01Z
GO:2000600
positive regulation of cellular protein breakdown
positive regulation of cellular protein catabolism
positive regulation of cellular protein degradation
up regulation of cellular protein breakdown
up regulation of cellular protein catabolic process
up regulation of cellular protein catabolism
up regulation of cellular protein degradation
up-regulation of cellular protein breakdown
up-regulation of cellular protein catabolic process
up-regulation of cellular protein catabolism
up-regulation of cellular protein degradation
upregulation of cellular protein breakdown
upregulation of cellular protein catabolic process
upregulation of cellular protein catabolism
upregulation of cellular protein degradation
activation of cellular protein breakdown
activation of cellular protein catabolic process
activation of cellular protein catabolism
activation of cellular protein degradation
positive regulation of cyclin breakdown
positive regulation of cyclin catabolic process
positive regulation of cyclin catabolism
positive regulation of cyclin degradation
positive regulation of degradation of cyclin
biological_process
positive regulation of cellular protein catabolic process
Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process.
GOC:TermGenie
GOC:kmv
GOC:obol
GO_REF:0000058
PMID:24785082
positive regulation of cellular protein breakdown
GOC:TermGenie
positive regulation of cellular protein catabolism
GOC:TermGenie
positive regulation of cellular protein degradation
GOC:TermGenie
up regulation of cellular protein breakdown
GOC:TermGenie
up regulation of cellular protein catabolic process
GOC:TermGenie
up regulation of cellular protein catabolism
GOC:TermGenie
up regulation of cellular protein degradation
GOC:TermGenie
up-regulation of cellular protein breakdown
GOC:TermGenie
up-regulation of cellular protein catabolic process
GOC:TermGenie
up-regulation of cellular protein catabolism
GOC:TermGenie
up-regulation of cellular protein degradation
GOC:TermGenie
upregulation of cellular protein breakdown
GOC:TermGenie
upregulation of cellular protein catabolic process
GOC:TermGenie
upregulation of cellular protein catabolism
GOC:TermGenie
upregulation of cellular protein degradation
GOC:TermGenie
activation of cellular protein breakdown
GOC:TermGenie
activation of cellular protein catabolic process
GOC:TermGenie
activation of cellular protein catabolism
GOC:TermGenie
activation of cellular protein degradation
GOC:TermGenie
positive regulation of cyclin breakdown
GOC:obol
positive regulation of cyclin catabolism
GOC:obol
positive regulation of cyclin degradation
GOC:obol
positive regulation of degradation of cyclin
GOC:obol
Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.
pr
2014-10-01T14:44:47Z
biological_process
regulation of nucleic acid-templated transcription
Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.
GOC:TermGenie
GOC:pr
GOC:txnOH
GOC:vw
GO_REF:0000058
Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.
pr
2014-10-01T14:44:56Z
down regulation of nucleic acid-templated transcription
down-regulation of nucleic acid-templated transcription
downregulation of nucleic acid-templated transcription
inhibition of nucleic acid-templated transcription
biological_process
negative regulation of nucleic acid-templated transcription
Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.
GOC:TermGenie
GOC:pr
GOC:txnOH
GOC:vw
GO_REF:0000058
down regulation of nucleic acid-templated transcription
GOC:TermGenie
down-regulation of nucleic acid-templated transcription
GOC:TermGenie
downregulation of nucleic acid-templated transcription
GOC:TermGenie
inhibition of nucleic acid-templated transcription
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription.
pr
2014-10-01T14:45:04Z
up regulation of nucleic acid-templated transcription
up-regulation of nucleic acid-templated transcription
upregulation of nucleic acid-templated transcription
activation of nucleic acid-templated transcription
biological_process
positive regulation of nucleic acid-templated transcription
Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription.
GOC:TermGenie
GOC:pr
GOC:txnOH
GOC:vw
GO_REF:0000058
up regulation of nucleic acid-templated transcription
GOC:TermGenie
up-regulation of nucleic acid-templated transcription
GOC:TermGenie
upregulation of nucleic acid-templated transcription
GOC:TermGenie
activation of nucleic acid-templated transcription
GOC:TermGenie
The directed movement of substances from endoplasmic reticulum to cytosol.
rl
2014-10-02T11:24:34Z
ER to cytosol transport
biological_process
endoplasmic reticulum to cytosol transport
The directed movement of substances from endoplasmic reticulum to cytosol.
GOC:BHF
GOC:TermGenie
GOC:mtg_cardiac_conduct_nov11
GOC:rl
GO_REF:0000076
PMID:16402920
ER to cytosol transport
GOC:TermGenie
Any process that modulates the frequency, rate or extent of secretion by cell.
pm
2014-10-08T13:24:59Z
regulation of cellular secretion
biological_process
regulation of secretion by cell
Any process that modulates the frequency, rate or extent of secretion by cell.
GOC:TermGenie
GOC:pm
GO_REF:0000058
PMID:12130530
regulation of cellular secretion
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.
pm
2014-10-08T13:25:08Z
down regulation of cellular secretion
down regulation of secretion by cell
down-regulation of cellular secretion
down-regulation of secretion by cell
downregulation of cellular secretion
downregulation of secretion by cell
negative regulation of cellular secretion
inhibition of cellular secretion
inhibition of secretion by cell
biological_process
negative regulation of secretion by cell
Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.
GOC:TermGenie
GOC:pm
GO_REF:0000058
PMID:12130530
down regulation of cellular secretion
GOC:TermGenie
down regulation of secretion by cell
GOC:TermGenie
down-regulation of cellular secretion
GOC:TermGenie
down-regulation of secretion by cell
GOC:TermGenie
downregulation of cellular secretion
GOC:TermGenie
downregulation of secretion by cell
GOC:TermGenie
negative regulation of cellular secretion
GOC:TermGenie
inhibition of cellular secretion
GOC:TermGenie
inhibition of secretion by cell
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of secretion by cell.
pm
2014-10-08T13:25:17Z
positive regulation of cellular secretion
up regulation of cellular secretion
up regulation of secretion by cell
up-regulation of cellular secretion
up-regulation of secretion by cell
upregulation of cellular secretion
upregulation of secretion by cell
activation of cellular secretion
activation of secretion by cell
biological_process
positive regulation of secretion by cell
Any process that activates or increases the frequency, rate or extent of secretion by cell.
GOC:TermGenie
GOC:pm
GO_REF:0000058
PMID:12130530
positive regulation of cellular secretion
GOC:TermGenie
up regulation of cellular secretion
GOC:TermGenie
up regulation of secretion by cell
GOC:TermGenie
up-regulation of cellular secretion
GOC:TermGenie
up-regulation of secretion by cell
GOC:TermGenie
upregulation of cellular secretion
GOC:TermGenie
upregulation of secretion by cell
GOC:TermGenie
activation of cellular secretion
GOC:TermGenie
activation of secretion by cell
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein targeting.
al
2014-10-08T14:49:03Z
regulation of protein sorting along secretory pathway
biological_process
regulation of nascent polypeptide association
regulation of protein targeting
Any process that modulates the frequency, rate or extent of protein targeting.
GOC:TermGenie
GO_REF:0000058
regulation of protein sorting along secretory pathway
GOC:TermGenie
regulation of nascent polypeptide association
GOC:TermGenie
Any vesicle that is part of the extracellular region.
jl
2014-10-22T14:26:11Z
cellular_component
microparticle
extracellular vesicle
Any vesicle that is part of the extracellular region.
GOC:TermGenie
GOC:pm
GO_REF:0000064
PMID:24769233
microparticle
GOC:vesicles
Any process that modulates the frequency, rate or extent of protein localization to cilium.
krc
2014-10-24T20:58:11Z
biological_process
regulation of protein localization to cilium
Any process that modulates the frequency, rate or extent of protein localization to cilium.
GOC:TermGenie
GOC:cilia
GOC:krc
GO_REF:0000058
PMID:22072986
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.
krc
2014-10-24T20:58:20Z
down regulation of protein localization to cilium
down-regulation of protein localization to cilium
downregulation of protein localization to cilium
inhibition of protein localization to cilium
biological_process
negative regulation of protein localization to cilium
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.
GOC:TermGenie
GOC:cilia
GOC:krc
GO_REF:0000058
PMID:22072986
down regulation of protein localization to cilium
GOC:TermGenie
down-regulation of protein localization to cilium
GOC:TermGenie
downregulation of protein localization to cilium
GOC:TermGenie
inhibition of protein localization to cilium
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein localization to cilium.
krc
2014-10-24T20:58:28Z
up regulation of protein localization to cilium
up-regulation of protein localization to cilium
upregulation of protein localization to cilium
activation of protein localization to cilium
biological_process
positive regulation of protein localization to cilium
Any process that activates or increases the frequency, rate or extent of protein localization to cilium.
GOC:TermGenie
GOC:cilia
GOC:krc
GO_REF:0000058
PMID:22072986
up regulation of protein localization to cilium
GOC:TermGenie
up-regulation of protein localization to cilium
GOC:TermGenie
upregulation of protein localization to cilium
GOC:TermGenie
activation of protein localization to cilium
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.
bf
2014-10-27T16:15:30Z
down regulation of ER stress response
down regulation of cellular response to endoplasmic reticulum stress
down regulation of response to ER stress
down regulation of response to endoplasmic reticulum stress
down-regulation of ER stress response
down-regulation of cellular response to endoplasmic reticulum stress
down-regulation of response to ER stress
down-regulation of response to endoplasmic reticulum stress
downregulation of ER stress response
downregulation of cellular response to endoplasmic reticulum stress
downregulation of response to ER stress
downregulation of response to endoplasmic reticulum stress
negative regulation of ER stress response
negative regulation of cellular response to endoplasmic reticulum stress
negative regulation of response to ER stress
inhibition of ER stress response
inhibition of cellular response to endoplasmic reticulum stress
inhibition of response to ER stress
inhibition of response to endoplasmic reticulum stress
biological_process
negative regulation of response to endoplasmic reticulum stress
Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
PMID:11381086
down regulation of ER stress response
GOC:TermGenie
down regulation of cellular response to endoplasmic reticulum stress
GOC:TermGenie
down regulation of response to ER stress
GOC:TermGenie
down regulation of response to endoplasmic reticulum stress
GOC:TermGenie
down-regulation of ER stress response
GOC:TermGenie
down-regulation of cellular response to endoplasmic reticulum stress
GOC:TermGenie
down-regulation of response to ER stress
GOC:TermGenie
down-regulation of response to endoplasmic reticulum stress
GOC:TermGenie
downregulation of ER stress response
GOC:TermGenie
downregulation of cellular response to endoplasmic reticulum stress
GOC:TermGenie
downregulation of response to ER stress
GOC:TermGenie
downregulation of response to endoplasmic reticulum stress
GOC:TermGenie
negative regulation of ER stress response
GOC:TermGenie
negative regulation of cellular response to endoplasmic reticulum stress
GOC:TermGenie
negative regulation of response to ER stress
GOC:TermGenie
inhibition of ER stress response
GOC:TermGenie
inhibition of cellular response to endoplasmic reticulum stress
GOC:TermGenie
inhibition of response to ER stress
GOC:TermGenie
inhibition of response to endoplasmic reticulum stress
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy.
pad
2014-11-10T14:25:53Z
positive regulation of mitochondrial degradation
up regulation of mitochondrion degradation
up-regulation of mitochondrion degradation
upregulation of mitochondrion degradation
up regulation of mitophagy
up-regulation of mitophagy
upregulation of mitophagy
activation of mitophagy
biological_process
activation of mitochondrion degradation
An example of this AMBRA1 - human (Q9C0C7) in PMID:21753002 inferred from direct assay
positive regulation of autophagy of mitochondrion
Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy.
GOC:PARL
GOC:TermGenie
GOC:autophagy
GOC:pad
GO_REF:0000058
PMID:21753002
positive regulation of mitochondrial degradation
GOC:TermGenie
up regulation of mitochondrion degradation
GOC:TermGenie
up-regulation of mitochondrion degradation
GOC:TermGenie
upregulation of mitochondrion degradation
GOC:TermGenie
up regulation of mitophagy
GOC:TermGenie
up-regulation of mitophagy
GOC:TermGenie
upregulation of mitophagy
GOC:TermGenie
activation of mitophagy
GOC:TermGenie
activation of mitochondrion degradation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of DNA catabolic process.
sl
2014-11-19T22:36:35Z
regulation of DNA breakdown
regulation of DNA catabolism
regulation of DNA degradation
biological_process
regulation of DNA catabolic process
Any process that modulates the frequency, rate or extent of DNA catabolic process.
GOC:TermGenie
GO_REF:0000058
PMID:2001740
regulation of DNA breakdown
GOC:TermGenie
regulation of DNA catabolism
GOC:TermGenie
regulation of DNA degradation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.
sl
2014-11-19T22:36:43Z
down regulation of DNA breakdown
down regulation of DNA catabolic process
down regulation of DNA catabolism
down regulation of DNA degradation
down-regulation of DNA breakdown
down-regulation of DNA catabolic process
down-regulation of DNA catabolism
down-regulation of DNA degradation
downregulation of DNA breakdown
downregulation of DNA catabolic process
downregulation of DNA catabolism
downregulation of DNA degradation
negative regulation of DNA breakdown
negative regulation of DNA catabolism
negative regulation of DNA degradation
inhibition of DNA breakdown
inhibition of DNA catabolic process
inhibition of DNA catabolism
inhibition of DNA degradation
biological_process
negative regulation of DNA catabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.
GOC:TermGenie
GO_REF:0000058
PMID:2001740
down regulation of DNA breakdown
GOC:TermGenie
down regulation of DNA catabolic process
GOC:TermGenie
down regulation of DNA catabolism
GOC:TermGenie
down regulation of DNA degradation
GOC:TermGenie
down-regulation of DNA breakdown
GOC:TermGenie
down-regulation of DNA catabolic process
GOC:TermGenie
down-regulation of DNA catabolism
GOC:TermGenie
down-regulation of DNA degradation
GOC:TermGenie
downregulation of DNA breakdown
GOC:TermGenie
downregulation of DNA catabolic process
GOC:TermGenie
downregulation of DNA catabolism
GOC:TermGenie
downregulation of DNA degradation
GOC:TermGenie
negative regulation of DNA breakdown
GOC:TermGenie
negative regulation of DNA catabolism
GOC:TermGenie
negative regulation of DNA degradation
GOC:TermGenie
inhibition of DNA breakdown
GOC:TermGenie
inhibition of DNA catabolic process
GOC:TermGenie
inhibition of DNA catabolism
GOC:TermGenie
inhibition of DNA degradation
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of DNA catabolic process.
sl
2014-11-19T22:36:51Z
positive regulation of DNA breakdown
positive regulation of DNA catabolism
positive regulation of DNA degradation
up regulation of DNA breakdown
up regulation of DNA catabolic process
up regulation of DNA catabolism
up regulation of DNA degradation
up-regulation of DNA breakdown
up-regulation of DNA catabolic process
up-regulation of DNA catabolism
up-regulation of DNA degradation
upregulation of DNA breakdown
upregulation of DNA catabolic process
upregulation of DNA catabolism
upregulation of DNA degradation
activation of DNA breakdown
activation of DNA catabolic process
activation of DNA catabolism
activation of DNA degradation
biological_process
positive regulation of DNA catabolic process
Any process that activates or increases the frequency, rate or extent of DNA catabolic process.
GOC:TermGenie
GO_REF:0000058
PMID:2001740
positive regulation of DNA breakdown
GOC:TermGenie
positive regulation of DNA catabolism
GOC:TermGenie
positive regulation of DNA degradation
GOC:TermGenie
up regulation of DNA breakdown
GOC:TermGenie
up regulation of DNA catabolic process
GOC:TermGenie
up regulation of DNA catabolism
GOC:TermGenie
up regulation of DNA degradation
GOC:TermGenie
up-regulation of DNA breakdown
GOC:TermGenie
up-regulation of DNA catabolic process
GOC:TermGenie
up-regulation of DNA catabolism
GOC:TermGenie
up-regulation of DNA degradation
GOC:TermGenie
upregulation of DNA breakdown
GOC:TermGenie
upregulation of DNA catabolic process
GOC:TermGenie
upregulation of DNA catabolism
GOC:TermGenie
upregulation of DNA degradation
GOC:TermGenie
activation of DNA breakdown
GOC:TermGenie
activation of DNA catabolic process
GOC:TermGenie
activation of DNA catabolism
GOC:TermGenie
activation of DNA degradation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of cytoplasmic transport.
jl
2014-11-24T13:38:17Z
regulation of cytoplasmic streaming
biological_process
regulation of cytoplasmic transport
Any process that modulates the frequency, rate or extent of cytoplasmic transport.
GOC:TermGenie
GO_REF:0000058
PMID:25049409
regulation of cytoplasmic streaming
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport.
jl
2014-11-24T13:38:26Z
down regulation of cytoplasmic transport
down-regulation of cytoplasmic transport
downregulation of cytoplasmic transport
down regulation of cytoplasmic streaming
down-regulation of cytoplasmic streaming
downregulation of cytoplasmic streaming
inhibition of cytoplasmic streaming
inhibition of cytoplasmic transport
negative regulation of cytoplasmic streaming
biological_process
negative regulation of cytoplasmic transport
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport.
GOC:TermGenie
GO_REF:0000058
PMID:25049409
down regulation of cytoplasmic transport
GOC:TermGenie
down-regulation of cytoplasmic transport
GOC:TermGenie
downregulation of cytoplasmic transport
GOC:TermGenie
down regulation of cytoplasmic streaming
GOC:TermGenie
down-regulation of cytoplasmic streaming
GOC:TermGenie
downregulation of cytoplasmic streaming
GOC:TermGenie
inhibition of cytoplasmic streaming
GOC:TermGenie
inhibition of cytoplasmic transport
GOC:TermGenie
negative regulation of cytoplasmic streaming
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of cytoplasmic transport.
jl
2014-11-24T13:38:34Z
up regulation of cytoplasmic transport
up-regulation of cytoplasmic transport
upregulation of cytoplasmic transport
activation of cytoplasmic streaming
activation of cytoplasmic transport
positive regulation of cytoplasmic streaming
up regulation of cytoplasmic streaming
up-regulation of cytoplasmic streaming
upregulation of cytoplasmic streaming
biological_process
positive regulation of cytoplasmic transport
Any process that activates or increases the frequency, rate or extent of cytoplasmic transport.
GOC:TermGenie
GO_REF:0000058
PMID:25049409
up regulation of cytoplasmic transport
GOC:TermGenie
up-regulation of cytoplasmic transport
GOC:TermGenie
upregulation of cytoplasmic transport
GOC:TermGenie
activation of cytoplasmic streaming
GOC:TermGenie
activation of cytoplasmic transport
GOC:TermGenie
positive regulation of cytoplasmic streaming
GOC:TermGenie
up regulation of cytoplasmic streaming
GOC:TermGenie
up-regulation of cytoplasmic streaming
GOC:TermGenie
upregulation of cytoplasmic streaming
GOC:TermGenie
Any process that modulates the frequency, rate or extent of plasma membrane organization.
al
2014-12-10T18:59:44Z
regulation of plasma membrane organisation
biological_process
regulation of plasma membrane organization and biogenesis
regulation of plasma membrane organization
Any process that modulates the frequency, rate or extent of plasma membrane organization.
GOC:TermGenie
GO_REF:0000058
PMID:24514900
regulation of plasma membrane organisation
GOC:TermGenie
regulation of plasma membrane organization and biogenesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion.
krc
2014-12-12T22:18:09Z
regulation of establishment of protein localisation to mitochondrion
regulation of establishment of protein localization in mitochondrion
biological_process
regulation of establishment of protein localization to mitochondrion
Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion.
GOC:TermGenie
GO_REF:0000058
PMID:16857185
regulation of establishment of protein localisation to mitochondrion
GOC:TermGenie
regulation of establishment of protein localization in mitochondrion
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion.
krc
2014-12-12T22:18:18Z
down regulation of establishment of protein localisation to mitochondrion
down regulation of establishment of protein localization in mitochondrion
down regulation of establishment of protein localization to mitochondrion
down-regulation of establishment of protein localisation to mitochondrion
down-regulation of establishment of protein localization in mitochondrion
down-regulation of establishment of protein localization to mitochondrion
downregulation of establishment of protein localisation to mitochondrion
downregulation of establishment of protein localization in mitochondrion
downregulation of establishment of protein localization to mitochondrion
negative regulation of establishment of protein localisation to mitochondrion
negative regulation of establishment of protein localization in mitochondrion
inhibition of establishment of protein localisation to mitochondrion
inhibition of establishment of protein localization in mitochondrion
inhibition of establishment of protein localization to mitochondrion
biological_process
negative regulation of establishment of protein localization to mitochondrion
Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion.
GOC:TermGenie
GO_REF:0000058
PMID:16857185
down regulation of establishment of protein localisation to mitochondrion
GOC:TermGenie
down regulation of establishment of protein localization in mitochondrion
GOC:TermGenie
down regulation of establishment of protein localization to mitochondrion
GOC:TermGenie
down-regulation of establishment of protein localisation to mitochondrion
GOC:TermGenie
down-regulation of establishment of protein localization in mitochondrion
GOC:TermGenie
down-regulation of establishment of protein localization to mitochondrion
GOC:TermGenie
downregulation of establishment of protein localisation to mitochondrion
GOC:TermGenie
downregulation of establishment of protein localization in mitochondrion
GOC:TermGenie
downregulation of establishment of protein localization to mitochondrion
GOC:TermGenie
negative regulation of establishment of protein localisation to mitochondrion
GOC:TermGenie
negative regulation of establishment of protein localization in mitochondrion
GOC:TermGenie
inhibition of establishment of protein localisation to mitochondrion
GOC:TermGenie
inhibition of establishment of protein localization in mitochondrion
GOC:TermGenie
inhibition of establishment of protein localization to mitochondrion
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion.
krc
2014-12-12T22:18:26Z
positive regulation of establishment of protein localisation to mitochondrion
positive regulation of establishment of protein localization in mitochondrion
up regulation of establishment of protein localisation to mitochondrion
up regulation of establishment of protein localization in mitochondrion
up regulation of establishment of protein localization to mitochondrion
up-regulation of establishment of protein localisation to mitochondrion
up-regulation of establishment of protein localization in mitochondrion
up-regulation of establishment of protein localization to mitochondrion
upregulation of establishment of protein localisation to mitochondrion
upregulation of establishment of protein localization in mitochondrion
upregulation of establishment of protein localization to mitochondrion
activation of establishment of protein localisation to mitochondrion
activation of establishment of protein localization in mitochondrion
activation of establishment of protein localization to mitochondrion
biological_process
positive regulation of establishment of protein localization to mitochondrion
Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion.
GOC:TermGenie
GO_REF:0000058
PMID:16857185
positive regulation of establishment of protein localisation to mitochondrion
GOC:TermGenie
positive regulation of establishment of protein localization in mitochondrion
GOC:TermGenie
up regulation of establishment of protein localisation to mitochondrion
GOC:TermGenie
up regulation of establishment of protein localization in mitochondrion
GOC:TermGenie
up regulation of establishment of protein localization to mitochondrion
GOC:TermGenie
up-regulation of establishment of protein localisation to mitochondrion
GOC:TermGenie
up-regulation of establishment of protein localization in mitochondrion
GOC:TermGenie
up-regulation of establishment of protein localization to mitochondrion
GOC:TermGenie
upregulation of establishment of protein localisation to mitochondrion
GOC:TermGenie
upregulation of establishment of protein localization in mitochondrion
GOC:TermGenie
upregulation of establishment of protein localization to mitochondrion
GOC:TermGenie
activation of establishment of protein localisation to mitochondrion
GOC:TermGenie
activation of establishment of protein localization in mitochondrion
GOC:TermGenie
activation of establishment of protein localization to mitochondrion
GOC:TermGenie
The process in which an organic acid is transported across a membrane.
vw
2015-01-20T10:20:58Z
biological_process
organic acid transmembrane transport
The process in which an organic acid is transported across a membrane.
GOC:TermGenie
GO_REF:0000069
Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
jl
2015-01-20T14:32:14Z
regulation of cellular protein localisation
regulation of channel localizer activity
biological_process
regulation of cellular protein localization
Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GOC:TermGenie
GOC:vw
GO_REF:0000058
regulation of cellular protein localisation
GOC:TermGenie
regulation of channel localizer activity
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
jl
2015-01-20T14:32:24Z
down regulation of cellular protein localisation
down regulation of cellular protein localization
down-regulation of cellular protein localisation
down-regulation of cellular protein localization
downregulation of cellular protein localisation
downregulation of cellular protein localization
negative regulation of cellular protein localisation
down regulation of channel localizer activity
down-regulation of channel localizer activity
downregulation of channel localizer activity
inhibition of cellular protein localisation
inhibition of cellular protein localization
inhibition of channel localizer activity
negative regulation of channel localizer activity
biological_process
negative regulation of cellular protein localization
Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GOC:TermGenie
GOC:vw
GO_REF:0000058
down regulation of cellular protein localisation
GOC:TermGenie
down regulation of cellular protein localization
GOC:TermGenie
down-regulation of cellular protein localisation
GOC:TermGenie
down-regulation of cellular protein localization
GOC:TermGenie
downregulation of cellular protein localisation
GOC:TermGenie
downregulation of cellular protein localization
GOC:TermGenie
negative regulation of cellular protein localisation
GOC:TermGenie
down regulation of channel localizer activity
GOC:TermGenie
down-regulation of channel localizer activity
GOC:TermGenie
downregulation of channel localizer activity
GOC:TermGenie
inhibition of cellular protein localisation
GOC:TermGenie
inhibition of cellular protein localization
GOC:TermGenie
inhibition of channel localizer activity
GOC:TermGenie
negative regulation of channel localizer activity
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
jl
2015-01-20T14:32:33Z
positive regulation of cellular protein localisation
up regulation of cellular protein localisation
up regulation of cellular protein localization
up-regulation of cellular protein localisation
up-regulation of cellular protein localization
upregulation of cellular protein localisation
upregulation of cellular protein localization
activation of cellular protein localisation
activation of cellular protein localization
activation of channel localizer activity
positive regulation of channel localizer activity
up regulation of channel localizer activity
up-regulation of channel localizer activity
upregulation of channel localizer activity
biological_process
positive regulation of cellular protein localization
Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GOC:TermGenie
GOC:vw
GO_REF:0000058
positive regulation of cellular protein localisation
GOC:TermGenie
up regulation of cellular protein localisation
GOC:TermGenie
up regulation of cellular protein localization
GOC:TermGenie
up-regulation of cellular protein localisation
GOC:TermGenie
up-regulation of cellular protein localization
GOC:TermGenie
upregulation of cellular protein localisation
GOC:TermGenie
upregulation of cellular protein localization
GOC:TermGenie
activation of cellular protein localisation
GOC:TermGenie
activation of cellular protein localization
GOC:TermGenie
activation of channel localizer activity
GOC:TermGenie
positive regulation of channel localizer activity
GOC:TermGenie
up regulation of channel localizer activity
GOC:TermGenie
up-regulation of channel localizer activity
GOC:TermGenie
upregulation of channel localizer activity
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.
pad
2015-02-24T16:58:21Z
positive regulation of protein import into mitochondrion
positive regulation of protein targeting to mitochondria
positive regulation of protein-mitochondrial targeting
up regulation of protein import into mitochondrion
up regulation of protein targeting to mitochondria
up regulation of protein targeting to mitochondrion
up regulation of protein-mitochondrial targeting
up-regulation of protein import into mitochondrion
up-regulation of protein targeting to mitochondria
up-regulation of protein targeting to mitochondrion
up-regulation of protein-mitochondrial targeting
upregulation of protein import into mitochondrion
upregulation of protein targeting to mitochondria
upregulation of protein targeting to mitochondrion
upregulation of protein-mitochondrial targeting
activation of protein import into mitochondrion
activation of protein targeting to mitochondria
activation of protein targeting to mitochondrion
activation of protein-mitochondrial targeting
biological_process
activation of mitochondrial protein import
activation of mitochondrial translocation
positive regulation of mitochondrial protein import
positive regulation of mitochondrial translocation
up regulation of mitochondrial protein import
up regulation of mitochondrial translocation
up-regulation of mitochondrial protein import
up-regulation of mitochondrial translocation
upregulation of mitochondrial protein import
upregulation of mitochondrial translocation
An example of this is PINK1 in human (UniProt symbol Q9BXM7) in PMID:24270810 inferred from mutant phenotype.
positive regulation of protein targeting to mitochondrion
Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.
GOC:PARL
GOC:TermGenie
GOC:pad
GO_REF:0000058
PMID:24270810
positive regulation of protein import into mitochondrion
GOC:TermGenie
positive regulation of protein targeting to mitochondria
GOC:TermGenie
positive regulation of protein-mitochondrial targeting
GOC:TermGenie
up regulation of protein import into mitochondrion
GOC:TermGenie
up regulation of protein targeting to mitochondria
GOC:TermGenie
up regulation of protein targeting to mitochondrion
GOC:TermGenie
up regulation of protein-mitochondrial targeting
GOC:TermGenie
up-regulation of protein import into mitochondrion
GOC:TermGenie
up-regulation of protein targeting to mitochondria
GOC:TermGenie
up-regulation of protein targeting to mitochondrion
GOC:TermGenie
up-regulation of protein-mitochondrial targeting
GOC:TermGenie
upregulation of protein import into mitochondrion
GOC:TermGenie
upregulation of protein targeting to mitochondria
GOC:TermGenie
upregulation of protein targeting to mitochondrion
GOC:TermGenie
upregulation of protein-mitochondrial targeting
GOC:TermGenie
activation of protein import into mitochondrion
GOC:TermGenie
activation of protein targeting to mitochondria
GOC:TermGenie
activation of protein targeting to mitochondrion
GOC:TermGenie
activation of protein-mitochondrial targeting
GOC:TermGenie
activation of mitochondrial protein import
GOC:TermGenie
activation of mitochondrial translocation
GOC:TermGenie
positive regulation of mitochondrial protein import
GOC:TermGenie
positive regulation of mitochondrial translocation
GOC:TermGenie
up regulation of mitochondrial protein import
GOC:TermGenie
up regulation of mitochondrial translocation
GOC:TermGenie
up-regulation of mitochondrial protein import
GOC:TermGenie
up-regulation of mitochondrial translocation
GOC:TermGenie
upregulation of mitochondrial protein import
GOC:TermGenie
upregulation of mitochondrial translocation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
pad
2015-03-17T13:54:16Z
biological_process
An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).
regulation of protein targeting to vacuole involved in autophagy
Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
GOC:PARL
GOC:TermGenie
GOC:pad
GO_REF:0000058
PMID:22020285
Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
pad
2015-03-17T13:54:22Z
down regulation of protein targeting to vacuole involved in autophagy
down-regulation of protein targeting to vacuole involved in autophagy
downregulation of protein targeting to vacuole involved in autophagy
inhibition of protein targeting to vacuole involved in autophagy
biological_process
An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).
negative regulation of protein targeting to vacuole involved in autophagy
Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
GOC:PARL
GOC:TermGenie
GOC:pad
GO_REF:0000058
PMID:22020285
down regulation of protein targeting to vacuole involved in autophagy
GOC:TermGenie
down-regulation of protein targeting to vacuole involved in autophagy
GOC:TermGenie
downregulation of protein targeting to vacuole involved in autophagy
GOC:TermGenie
inhibition of protein targeting to vacuole involved in autophagy
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
pad
2015-03-17T13:54:27Z
up regulation of protein targeting to vacuole involved in autophagy
up-regulation of protein targeting to vacuole involved in autophagy
upregulation of protein targeting to vacuole involved in autophagy
activation of protein targeting to vacuole involved in autophagy
biological_process
An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).
positive regulation of protein targeting to vacuole involved in autophagy
Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
GOC:PARL
GOC:TermGenie
GOC:pad
GO_REF:0000058
PMID:22020285
up regulation of protein targeting to vacuole involved in autophagy
GOC:TermGenie
up-regulation of protein targeting to vacuole involved in autophagy
GOC:TermGenie
upregulation of protein targeting to vacuole involved in autophagy
GOC:TermGenie
activation of protein targeting to vacuole involved in autophagy
GOC:TermGenie
Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol.
bf
2015-04-15T09:23:06Z
regulation of protein dislocation from ER
regulation of protein retrotranslocation from ER
regulation of retrograde protein transport, endoplasmic reticulum to cytosol
biological_process
regulation of retrograde protein transport, ER to cytosol
Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
PMID:18555783
regulation of protein dislocation from ER
GOC:TermGenie
regulation of protein retrotranslocation from ER
GOC:bf
regulation of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.
bf
2015-04-15T09:23:13Z
down regulation of protein dislocation from ER
down regulation of retrograde protein transport, ER to cytosol
down regulation of retrograde protein transport, endoplasmic reticulum to cytosol
down-regulation of protein dislocation from ER
down-regulation of retrograde protein transport, ER to cytosol
down-regulation of retrograde protein transport, endoplasmic reticulum to cytosol
downregulation of protein dislocation from ER
downregulation of retrograde protein transport, ER to cytosol
downregulation of retrograde protein transport, endoplasmic reticulum to cytosol
negative regulation of protein dislocation from ER
negative regulation of protein retrotranslocation from ER
negative regulation of retrograde protein transport, endoplasmic reticulum to cytosol
inhibition of protein dislocation from ER
inhibition of retrograde protein transport, ER to cytosol
inhibition of retrograde protein transport, endoplasmic reticulum to cytosol
biological_process
negative regulation of retrograde protein transport, ER to cytosol
Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
PMID:18555783
down regulation of protein dislocation from ER
GOC:TermGenie
down regulation of retrograde protein transport, ER to cytosol
GOC:TermGenie
down regulation of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
down-regulation of protein dislocation from ER
GOC:TermGenie
down-regulation of retrograde protein transport, ER to cytosol
GOC:TermGenie
down-regulation of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
downregulation of protein dislocation from ER
GOC:TermGenie
downregulation of retrograde protein transport, ER to cytosol
GOC:TermGenie
downregulation of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
negative regulation of protein dislocation from ER
GOC:TermGenie
negative regulation of protein retrotranslocation from ER
GOC:bf
negative regulation of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
inhibition of protein dislocation from ER
GOC:TermGenie
inhibition of retrograde protein transport, ER to cytosol
GOC:TermGenie
inhibition of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol.
bf
2015-04-15T09:23:19Z
positive regulation of protein dislocation from ER
positive regulation of protein retrotranslocation from ER
positive regulation of retrograde protein transport, endoplasmic reticulum to cytosol
up regulation of protein dislocation from ER
up regulation of retrograde protein transport, ER to cytosol
up regulation of retrograde protein transport, endoplasmic reticulum to cytosol
up-regulation of protein dislocation from ER
up-regulation of protein retrotranslocation from ER
up-regulation of retrograde protein transport, ER to cytosol
up-regulation of retrograde protein transport, endoplasmic reticulum to cytosol
upregulation of protein dislocation from ER
upregulation of retrograde protein transport, ER to cytosol
upregulation of retrograde protein transport, endoplasmic reticulum to cytosol
activation of protein dislocation from ER
activation of retrograde protein transport, ER to cytosol
activation of retrograde protein transport, endoplasmic reticulum to cytosol
biological_process
positive regulation of retrograde protein transport, ER to cytosol
Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
PMID:18555783
positive regulation of protein dislocation from ER
GOC:TermGenie
positive regulation of protein retrotranslocation from ER
GOC:bf
positive regulation of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
up regulation of protein dislocation from ER
GOC:TermGenie
up regulation of retrograde protein transport, ER to cytosol
GOC:TermGenie
up regulation of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
up-regulation of protein dislocation from ER
GOC:TermGenie
up-regulation of protein retrotranslocation from ER
GOC:bf
up-regulation of retrograde protein transport, ER to cytosol
GOC:TermGenie
up-regulation of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
upregulation of protein dislocation from ER
GOC:TermGenie
upregulation of retrograde protein transport, ER to cytosol
GOC:TermGenie
upregulation of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
activation of protein dislocation from ER
GOC:TermGenie
activation of retrograde protein transport, ER to cytosol
GOC:TermGenie
activation of retrograde protein transport, endoplasmic reticulum to cytosol
GOC:TermGenie
Any process that modulates the frequency, rate or extent of ERAD pathway.
bf
2015-06-09T14:44:27Z
regulation of endoplasmic reticulum-associated degradation
biological_process
regulation of ER-associated degradation pathway
regulation of endoplasmic reticulum-associated protein degradation pathway
regulation of ERAD pathway
Any process that modulates the frequency, rate or extent of ERAD pathway.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
regulation of endoplasmic reticulum-associated degradation
GOC:TermGenie
regulation of ER-associated degradation pathway
GOC:TermGenie
regulation of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway.
bf
2015-06-09T14:44:33Z
down regulation of ERAD pathway
down regulation of endoplasmic reticulum-associated degradation
down-regulation of ERAD pathway
down-regulation of endoplasmic reticulum-associated degradation
downregulation of ERAD pathway
downregulation of endoplasmic reticulum-associated degradation
negative regulation of endoplasmic reticulum-associated degradation
inhibition of ERAD pathway
inhibition of endoplasmic reticulum-associated degradation
biological_process
down regulation of ER-associated degradation pathway
down regulation of endoplasmic reticulum-associated protein degradation pathway
down-regulation of ER-associated degradation pathway
down-regulation of endoplasmic reticulum-associated protein degradation pathway
downregulation of ER-associated degradation pathway
downregulation of endoplasmic reticulum-associated protein degradation pathway
inhibition of ER-associated degradation pathway
inhibition of endoplasmic reticulum-associated protein degradation pathway
negative regulation of ER-associated degradation pathway
negative regulation of endoplasmic reticulum-associated protein degradation pathway
negative regulation of ERAD pathway
Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
PMID:22590560
down regulation of ERAD pathway
GOC:TermGenie
down regulation of endoplasmic reticulum-associated degradation
GOC:TermGenie
down-regulation of ERAD pathway
GOC:TermGenie
down-regulation of endoplasmic reticulum-associated degradation
GOC:TermGenie
downregulation of ERAD pathway
GOC:TermGenie
downregulation of endoplasmic reticulum-associated degradation
GOC:TermGenie
negative regulation of endoplasmic reticulum-associated degradation
GOC:TermGenie
inhibition of ERAD pathway
GOC:TermGenie
inhibition of endoplasmic reticulum-associated degradation
GOC:TermGenie
down regulation of ER-associated degradation pathway
GOC:TermGenie
down regulation of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
down-regulation of ER-associated degradation pathway
GOC:TermGenie
down-regulation of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
downregulation of ER-associated degradation pathway
GOC:TermGenie
downregulation of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
inhibition of ER-associated degradation pathway
GOC:TermGenie
inhibition of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
negative regulation of ER-associated degradation pathway
GOC:TermGenie
negative regulation of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of ERAD pathway.
bf
2015-06-09T14:44:39Z
positive regulation of endoplasmic reticulum-associated degradation
up regulation of ERAD pathway
up regulation of endoplasmic reticulum-associated degradation
up-regulation of ERAD pathway
up-regulation of endoplasmic reticulum-associated degradation
upregulation of ERAD pathway
upregulation of endoplasmic reticulum-associated degradation
activation of ERAD pathway
activation of endoplasmic reticulum-associated degradation
biological_process
activation of ER-associated degradation pathway
activation of endoplasmic reticulum-associated protein degradation pathway
positive regulation of ER-associated degradation pathway
positive regulation of endoplasmic reticulum-associated protein degradation pathway
up regulation of ER-associated degradation pathway
up regulation of endoplasmic reticulum-associated protein degradation pathway
up-regulation of ER-associated degradation pathway
up-regulation of endoplasmic reticulum-associated protein degradation pathway
upregulation of ER-associated degradation pathway
upregulation of endoplasmic reticulum-associated protein degradation pathway
positive regulation of ERAD pathway
Any process that activates or increases the frequency, rate or extent of ERAD pathway.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
positive regulation of endoplasmic reticulum-associated degradation
GOC:TermGenie
up regulation of ERAD pathway
GOC:TermGenie
up regulation of endoplasmic reticulum-associated degradation
GOC:TermGenie
up-regulation of ERAD pathway
GOC:TermGenie
up-regulation of endoplasmic reticulum-associated degradation
GOC:TermGenie
upregulation of ERAD pathway
GOC:TermGenie
upregulation of endoplasmic reticulum-associated degradation
GOC:TermGenie
activation of ERAD pathway
GOC:TermGenie
activation of endoplasmic reticulum-associated degradation
GOC:TermGenie
activation of ER-associated degradation pathway
GOC:TermGenie
activation of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
positive regulation of ER-associated degradation pathway
GOC:TermGenie
positive regulation of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
up regulation of ER-associated degradation pathway
GOC:TermGenie
up regulation of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
up-regulation of ER-associated degradation pathway
GOC:TermGenie
up-regulation of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
upregulation of ER-associated degradation pathway
GOC:TermGenie
upregulation of endoplasmic reticulum-associated protein degradation pathway
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole.
rl
2015-06-12T09:10:36Z
biological_process
regulation of vacuolar protein breakdown
regulation of vacuolar protein catabolic process
regulation of vacuolar protein catabolism
regulation of vacuolar protein degradation
regulation of protein catabolic process in the vacuole
Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:25635054
regulation of vacuolar protein breakdown
GOC:TermGenie
regulation of vacuolar protein catabolic process
GOC:TermGenie
regulation of vacuolar protein catabolism
GOC:TermGenie
regulation of vacuolar protein degradation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole.
rl
2015-06-12T09:10:42Z
down regulation of protein catabolic process in the vacuole
down-regulation of protein catabolic process in the vacuole
downregulation of protein catabolic process in the vacuole
inhibition of protein catabolic process in the vacuole
biological_process
down regulation of vacuolar protein breakdown
down regulation of vacuolar protein catabolic process
down regulation of vacuolar protein catabolism
down regulation of vacuolar protein degradation
down-regulation of vacuolar protein breakdown
down-regulation of vacuolar protein catabolic process
down-regulation of vacuolar protein catabolism
down-regulation of vacuolar protein degradation
downregulation of vacuolar protein breakdown
downregulation of vacuolar protein catabolic process
downregulation of vacuolar protein catabolism
downregulation of vacuolar protein degradation
inhibition of vacuolar protein breakdown
inhibition of vacuolar protein catabolic process
inhibition of vacuolar protein catabolism
inhibition of vacuolar protein degradation
negative regulation of vacuolar protein breakdown
negative regulation of vacuolar protein catabolic process
negative regulation of vacuolar protein catabolism
negative regulation of vacuolar protein degradation
negative regulation of protein catabolic process in the vacuole
Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:25635054
down regulation of protein catabolic process in the vacuole
GOC:TermGenie
down-regulation of protein catabolic process in the vacuole
GOC:TermGenie
downregulation of protein catabolic process in the vacuole
GOC:TermGenie
inhibition of protein catabolic process in the vacuole
GOC:TermGenie
down regulation of vacuolar protein breakdown
GOC:TermGenie
down regulation of vacuolar protein catabolic process
GOC:TermGenie
down regulation of vacuolar protein catabolism
GOC:TermGenie
down regulation of vacuolar protein degradation
GOC:TermGenie
down-regulation of vacuolar protein breakdown
GOC:TermGenie
down-regulation of vacuolar protein catabolic process
GOC:TermGenie
down-regulation of vacuolar protein catabolism
GOC:TermGenie
down-regulation of vacuolar protein degradation
GOC:TermGenie
downregulation of vacuolar protein breakdown
GOC:TermGenie
downregulation of vacuolar protein catabolic process
GOC:TermGenie
downregulation of vacuolar protein catabolism
GOC:TermGenie
downregulation of vacuolar protein degradation
GOC:TermGenie
inhibition of vacuolar protein breakdown
GOC:TermGenie
inhibition of vacuolar protein catabolic process
GOC:TermGenie
inhibition of vacuolar protein catabolism
GOC:TermGenie
inhibition of vacuolar protein degradation
GOC:TermGenie
negative regulation of vacuolar protein breakdown
GOC:TermGenie
negative regulation of vacuolar protein catabolic process
GOC:TermGenie
negative regulation of vacuolar protein catabolism
GOC:TermGenie
negative regulation of vacuolar protein degradation
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole.
rl
2015-06-12T09:10:49Z
up regulation of protein catabolic process in the vacuole
up-regulation of protein catabolic process in the vacuole
upregulation of protein catabolic process in the vacuole
activation of protein catabolic process in the vacuole
biological_process
activation of vacuolar protein breakdown
activation of vacuolar protein catabolic process
activation of vacuolar protein catabolism
activation of vacuolar protein degradation
positive regulation of vacuolar protein breakdown
positive regulation of vacuolar protein catabolic process
positive regulation of vacuolar protein catabolism
positive regulation of vacuolar protein degradation
up regulation of vacuolar protein breakdown
up regulation of vacuolar protein catabolic process
up regulation of vacuolar protein catabolism
up regulation of vacuolar protein degradation
up-regulation of vacuolar protein breakdown
up-regulation of vacuolar protein catabolic process
up-regulation of vacuolar protein catabolism
up-regulation of vacuolar protein degradation
upregulation of vacuolar protein breakdown
upregulation of vacuolar protein catabolic process
upregulation of vacuolar protein catabolism
upregulation of vacuolar protein degradation
positive regulation of protein catabolic process in the vacuole
Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole.
GOC:BHF
GOC:TermGenie
GOC:rl
GO_REF:0000058
PMID:25635054
up regulation of protein catabolic process in the vacuole
GOC:TermGenie
up-regulation of protein catabolic process in the vacuole
GOC:TermGenie
upregulation of protein catabolic process in the vacuole
GOC:TermGenie
activation of protein catabolic process in the vacuole
GOC:TermGenie
activation of vacuolar protein breakdown
GOC:TermGenie
activation of vacuolar protein catabolic process
GOC:TermGenie
activation of vacuolar protein catabolism
GOC:TermGenie
activation of vacuolar protein degradation
GOC:TermGenie
positive regulation of vacuolar protein breakdown
GOC:TermGenie
positive regulation of vacuolar protein catabolic process
GOC:TermGenie
positive regulation of vacuolar protein catabolism
GOC:TermGenie
positive regulation of vacuolar protein degradation
GOC:TermGenie
up regulation of vacuolar protein breakdown
GOC:TermGenie
up regulation of vacuolar protein catabolic process
GOC:TermGenie
up regulation of vacuolar protein catabolism
GOC:TermGenie
up regulation of vacuolar protein degradation
GOC:TermGenie
up-regulation of vacuolar protein breakdown
GOC:TermGenie
up-regulation of vacuolar protein catabolic process
GOC:TermGenie
up-regulation of vacuolar protein catabolism
GOC:TermGenie
up-regulation of vacuolar protein degradation
GOC:TermGenie
upregulation of vacuolar protein breakdown
GOC:TermGenie
upregulation of vacuolar protein catabolic process
GOC:TermGenie
upregulation of vacuolar protein catabolism
GOC:TermGenie
upregulation of vacuolar protein degradation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein localization to cell periphery.
sl
2015-06-22T22:09:25Z
biological_process
regulation of protein localization to cell periphery
Any process that modulates the frequency, rate or extent of protein localization to cell periphery.
GOC:TermGenie
GO_REF:0000058
PMID:18216290
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery.
sl
2015-06-22T22:09:32Z
down regulation of protein localization to cell periphery
down-regulation of protein localization to cell periphery
downregulation of protein localization to cell periphery
inhibition of protein localization to cell periphery
biological_process
negative regulation of protein localization to cell periphery
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery.
GOC:TermGenie
GO_REF:0000058
PMID:18216290
down regulation of protein localization to cell periphery
GOC:TermGenie
down-regulation of protein localization to cell periphery
GOC:TermGenie
downregulation of protein localization to cell periphery
GOC:TermGenie
inhibition of protein localization to cell periphery
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery.
sl
2015-06-22T22:09:37Z
up regulation of protein localization to cell periphery
up-regulation of protein localization to cell periphery
upregulation of protein localization to cell periphery
activation of protein localization to cell periphery
biological_process
positive regulation of protein localization to cell periphery
Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery.
GOC:TermGenie
GO_REF:0000058
PMID:18216290
up regulation of protein localization to cell periphery
GOC:TermGenie
up-regulation of protein localization to cell periphery
GOC:TermGenie
upregulation of protein localization to cell periphery
GOC:TermGenie
activation of protein localization to cell periphery
GOC:TermGenie
A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone.
kmv
2015-07-17T20:43:21Z
protein localisation in ciliary transition zone
protein localisation to ciliary transition zone
protein localization in ciliary transition zone
biological_process
protein localization to ciliary transition zone
A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone.
GOC:TermGenie
GOC:kmv
GO_REF:0000087
PMID:21422230
protein localisation in ciliary transition zone
GOC:TermGenie
protein localisation to ciliary transition zone
GOC:TermGenie
protein localization in ciliary transition zone
GOC:TermGenie
Any process that modulates the frequency, rate or extent of microtubule binding.
als
2015-07-30T10:32:13Z
biological_process
regulation of microtubule severing activity
regulation of microtubule/chromatin interaction
regulation of microtubule binding
Any process that modulates the frequency, rate or extent of microtubule binding.
GOC:TermGenie
GOC:als
GO_REF:0000059
PMID:24520051
regulation of microtubule severing activity
GOC:TermGenie
regulation of microtubule/chromatin interaction
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding.
als
2015-07-30T10:32:29Z
down regulation of microtubule binding
down-regulation of microtubule binding
downregulation of microtubule binding
inhibition of microtubule binding
biological_process
down regulation of microtubule severing activity
down regulation of microtubule/chromatin interaction
down-regulation of microtubule severing activity
down-regulation of microtubule/chromatin interaction
downregulation of microtubule severing activity
downregulation of microtubule/chromatin interaction
inhibition of microtubule severing activity
inhibition of microtubule/chromatin interaction
negative regulation of microtubule severing activity
negative regulation of microtubule/chromatin interaction
negative regulation of microtubule binding
Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding.
GOC:TermGenie
GOC:als
GO_REF:0000059
PMID:24520051
down regulation of microtubule binding
GOC:TermGenie
down-regulation of microtubule binding
GOC:TermGenie
downregulation of microtubule binding
GOC:TermGenie
inhibition of microtubule binding
GOC:TermGenie
down regulation of microtubule severing activity
GOC:TermGenie
down regulation of microtubule/chromatin interaction
GOC:TermGenie
down-regulation of microtubule severing activity
GOC:TermGenie
down-regulation of microtubule/chromatin interaction
GOC:TermGenie
downregulation of microtubule severing activity
GOC:TermGenie
downregulation of microtubule/chromatin interaction
GOC:TermGenie
inhibition of microtubule severing activity
GOC:TermGenie
inhibition of microtubule/chromatin interaction
GOC:TermGenie
negative regulation of microtubule severing activity
GOC:TermGenie
negative regulation of microtubule/chromatin interaction
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of microtubule binding.
als
2015-07-30T10:32:36Z
up regulation of microtubule binding
up-regulation of microtubule binding
upregulation of microtubule binding
activation of microtubule binding
biological_process
activation of microtubule severing activity
activation of microtubule/chromatin interaction
positive regulation of microtubule severing activity
positive regulation of microtubule/chromatin interaction
up regulation of microtubule severing activity
up regulation of microtubule/chromatin interaction
up-regulation of microtubule severing activity
up-regulation of microtubule/chromatin interaction
upregulation of microtubule severing activity
upregulation of microtubule/chromatin interaction
positive regulation of microtubule binding
Any process that activates or increases the frequency, rate or extent of microtubule binding.
GOC:TermGenie
GOC:als
GO_REF:0000059
PMID:24520051
up regulation of microtubule binding
GOC:TermGenie
up-regulation of microtubule binding
GOC:TermGenie
upregulation of microtubule binding
GOC:TermGenie
activation of microtubule binding
GOC:TermGenie
activation of microtubule severing activity
GOC:TermGenie
activation of microtubule/chromatin interaction
GOC:TermGenie
positive regulation of microtubule severing activity
GOC:TermGenie
positive regulation of microtubule/chromatin interaction
GOC:TermGenie
up regulation of microtubule severing activity
GOC:TermGenie
up regulation of microtubule/chromatin interaction
GOC:TermGenie
up-regulation of microtubule severing activity
GOC:TermGenie
up-regulation of microtubule/chromatin interaction
GOC:TermGenie
upregulation of microtubule severing activity
GOC:TermGenie
upregulation of microtubule/chromatin interaction
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding.
sl
2015-08-19T17:51:03Z
down regulation of mRNA binding
down-regulation of mRNA binding
downregulation of mRNA binding
inhibition of mRNA binding
biological_process
negative regulation of mRNA binding
Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding.
GOC:TermGenie
GO_REF:0000059
PMID:19716792
down regulation of mRNA binding
GOC:TermGenie
down-regulation of mRNA binding
GOC:TermGenie
downregulation of mRNA binding
GOC:TermGenie
inhibition of mRNA binding
GOC:TermGenie
Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation.
dos
2015-09-25T14:39:38Z
biological_process
regulation of cytoplasmic translational initiation
Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation.
GOC:TermGenie
GO_REF:0000058
PMID:12242291
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation.
dos
2015-09-25T14:39:44Z
down regulation of cytoplasmic translational initiation
down-regulation of cytoplasmic translational initiation
downregulation of cytoplasmic translational initiation
inhibition of cytoplasmic translational initiation
biological_process
negative regulation of cytoplasmic translational initiation
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation.
GOC:TermGenie
GO_REF:0000058
PMID:12242291
down regulation of cytoplasmic translational initiation
GOC:TermGenie
down-regulation of cytoplasmic translational initiation
GOC:TermGenie
downregulation of cytoplasmic translational initiation
GOC:TermGenie
inhibition of cytoplasmic translational initiation
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation.
dos
2015-09-25T14:39:50Z
up regulation of cytoplasmic translational initiation
up-regulation of cytoplasmic translational initiation
upregulation of cytoplasmic translational initiation
activation of cytoplasmic translational initiation
biological_process
positive regulation of cytoplasmic translational initiation
Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation.
GOC:TermGenie
GO_REF:0000058
PMID:12242291
up regulation of cytoplasmic translational initiation
GOC:TermGenie
up-regulation of cytoplasmic translational initiation
GOC:TermGenie
upregulation of cytoplasmic translational initiation
GOC:TermGenie
activation of cytoplasmic translational initiation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein localization to nucleolus.
nc
2015-10-19T15:16:17Z
regulation of protein localisation in nucleolus
regulation of protein localisation to nucleolus
regulation of protein localization in nucleolus
biological_process
regulation of protein localization to nucleolus
Any process that modulates the frequency, rate or extent of protein localization to nucleolus.
GOC:BHF
GOC:BHF_telomere
GOC:TermGenie
GOC:nc
GO_REF:0000058
PMID:24415760
regulation of protein localisation in nucleolus
GOC:TermGenie
regulation of protein localisation to nucleolus
GOC:TermGenie
regulation of protein localization in nucleolus
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus.
nc
2015-10-19T15:16:24Z
down regulation of protein localisation in nucleolus
down regulation of protein localisation to nucleolus
down regulation of protein localization in nucleolus
down regulation of protein localization to nucleolus
down-regulation of protein localisation in nucleolus
down-regulation of protein localisation to nucleolus
down-regulation of protein localization in nucleolus
down-regulation of protein localization to nucleolus
downregulation of protein localisation in nucleolus
downregulation of protein localisation to nucleolus
downregulation of protein localization in nucleolus
downregulation of protein localization to nucleolus
negative regulation of protein localisation in nucleolus
negative regulation of protein localisation to nucleolus
negative regulation of protein localization in nucleolus
inhibition of protein localisation in nucleolus
inhibition of protein localisation to nucleolus
inhibition of protein localization in nucleolus
inhibition of protein localization to nucleolus
biological_process
negative regulation of protein localization to nucleolus
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus.
GOC:BHF
GOC:BHF_telomere
GOC:TermGenie
GOC:nc
GO_REF:0000058
PMID:24415760
down regulation of protein localisation in nucleolus
GOC:TermGenie
down regulation of protein localisation to nucleolus
GOC:TermGenie
down regulation of protein localization in nucleolus
GOC:TermGenie
down regulation of protein localization to nucleolus
GOC:TermGenie
down-regulation of protein localisation in nucleolus
GOC:TermGenie
down-regulation of protein localisation to nucleolus
GOC:TermGenie
down-regulation of protein localization in nucleolus
GOC:TermGenie
down-regulation of protein localization to nucleolus
GOC:TermGenie
downregulation of protein localisation in nucleolus
GOC:TermGenie
downregulation of protein localisation to nucleolus
GOC:TermGenie
downregulation of protein localization in nucleolus
GOC:TermGenie
downregulation of protein localization to nucleolus
GOC:TermGenie
negative regulation of protein localisation in nucleolus
GOC:TermGenie
negative regulation of protein localisation to nucleolus
GOC:TermGenie
negative regulation of protein localization in nucleolus
GOC:TermGenie
inhibition of protein localisation in nucleolus
GOC:TermGenie
inhibition of protein localisation to nucleolus
GOC:TermGenie
inhibition of protein localization in nucleolus
GOC:TermGenie
inhibition of protein localization to nucleolus
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus.
nc
2015-10-19T15:16:30Z
positive regulation of protein localisation in nucleolus
positive regulation of protein localisation to nucleolus
positive regulation of protein localization in nucleolus
up regulation of protein localisation in nucleolus
up regulation of protein localisation to nucleolus
up regulation of protein localization in nucleolus
up regulation of protein localization to nucleolus
up-regulation of protein localisation in nucleolus
up-regulation of protein localisation to nucleolus
up-regulation of protein localization in nucleolus
up-regulation of protein localization to nucleolus
upregulation of protein localisation in nucleolus
upregulation of protein localisation to nucleolus
upregulation of protein localization in nucleolus
upregulation of protein localization to nucleolus
activation of protein localisation in nucleolus
activation of protein localisation to nucleolus
activation of protein localization in nucleolus
activation of protein localization to nucleolus
biological_process
positive regulation of protein localization to nucleolus
Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus.
GOC:BHF
GOC:BHF_telomere
GOC:TermGenie
GOC:nc
GO_REF:0000058
PMID:24415760
positive regulation of protein localisation in nucleolus
GOC:TermGenie
positive regulation of protein localisation to nucleolus
GOC:TermGenie
positive regulation of protein localization in nucleolus
GOC:TermGenie
up regulation of protein localisation in nucleolus
GOC:TermGenie
up regulation of protein localisation to nucleolus
GOC:TermGenie
up regulation of protein localization in nucleolus
GOC:TermGenie
up regulation of protein localization to nucleolus
GOC:TermGenie
up-regulation of protein localisation in nucleolus
GOC:TermGenie
up-regulation of protein localisation to nucleolus
GOC:TermGenie
up-regulation of protein localization in nucleolus
GOC:TermGenie
up-regulation of protein localization to nucleolus
GOC:TermGenie
upregulation of protein localisation in nucleolus
GOC:TermGenie
upregulation of protein localisation to nucleolus
GOC:TermGenie
upregulation of protein localization in nucleolus
GOC:TermGenie
upregulation of protein localization to nucleolus
GOC:TermGenie
activation of protein localisation in nucleolus
GOC:TermGenie
activation of protein localisation to nucleolus
GOC:TermGenie
activation of protein localization in nucleolus
GOC:TermGenie
activation of protein localization to nucleolus
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein localization to cell cortex.
es
2015-10-29T16:55:01Z
regulation of protein localisation to cell cortex
biological_process
An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.
regulation of protein localization to cell cortex
Any process that modulates the frequency, rate or extent of protein localization to cell cortex.
GOC:TermGenie
GO_REF:0000058
PMID:17115027
regulation of protein localisation to cell cortex
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex.
es
2015-10-29T16:55:08Z
down regulation of protein localisation to cell cortex
down regulation of protein localization to cell cortex
down-regulation of protein localisation to cell cortex
down-regulation of protein localization to cell cortex
downregulation of protein localisation to cell cortex
downregulation of protein localization to cell cortex
negative regulation of protein localisation to cell cortex
inhibition of protein localisation to cell cortex
inhibition of protein localization to cell cortex
biological_process
An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.
negative regulation of protein localization to cell cortex
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex.
GOC:TermGenie
GO_REF:0000058
PMID:17115027
down regulation of protein localisation to cell cortex
GOC:TermGenie
down regulation of protein localization to cell cortex
GOC:TermGenie
down-regulation of protein localisation to cell cortex
GOC:TermGenie
down-regulation of protein localization to cell cortex
GOC:TermGenie
downregulation of protein localisation to cell cortex
GOC:TermGenie
downregulation of protein localization to cell cortex
GOC:TermGenie
negative regulation of protein localisation to cell cortex
GOC:TermGenie
inhibition of protein localisation to cell cortex
GOC:TermGenie
inhibition of protein localization to cell cortex
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex.
es
2015-10-29T16:55:15Z
positive regulation of protein localisation to cell cortex
up regulation of protein localisation to cell cortex
up regulation of protein localization to cell cortex
up-regulation of protein localisation to cell cortex
up-regulation of protein localization to cell cortex
upregulation of protein localisation to cell cortex
upregulation of protein localization to cell cortex
activation of protein localisation to cell cortex
activation of protein localization to cell cortex
biological_process
An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.
positive regulation of protein localization to cell cortex
Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex.
GOC:TermGenie
GO_REF:0000058
PMID:17115027
positive regulation of protein localisation to cell cortex
GOC:TermGenie
up regulation of protein localisation to cell cortex
GOC:TermGenie
up regulation of protein localization to cell cortex
GOC:TermGenie
up-regulation of protein localisation to cell cortex
GOC:TermGenie
up-regulation of protein localization to cell cortex
GOC:TermGenie
upregulation of protein localisation to cell cortex
GOC:TermGenie
upregulation of protein localization to cell cortex
GOC:TermGenie
activation of protein localisation to cell cortex
GOC:TermGenie
activation of protein localization to cell cortex
GOC:TermGenie
A protein complex which is capable of ATPase activity.
bhm
2016-02-04T22:13:32Z
VPS4 complex
cellular_component
An example of this is VPS4 in Saccharomyces cerevisiae (UniProt ID P52917) in PMID:9606181 (inferred from direct assay).
ATPase complex
A protein complex which is capable of ATPase activity.
GOC:TermGenie
GOC:bhm
GO_REF:0000088
PMID:9606181
Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization.
mec
2016-02-05T09:59:24Z
down regulation of establishment of protein localisation
down regulation of establishment of protein localization
down regulation of protein positioning
down regulation of protein recruitment
down-regulation of establishment of protein localisation
down-regulation of establishment of protein localization
down-regulation of protein positioning
down-regulation of protein recruitment
downregulation of establishment of protein localisation
downregulation of establishment of protein localization
downregulation of protein positioning
downregulation of protein recruitment
negative regulation of establishment of protein localisation
negative regulation of protein positioning
negative regulation of protein recruitment
inhibition of establishment of protein localisation
inhibition of establishment of protein localization
inhibition of protein positioning
inhibition of protein recruitment
biological_process
negative regulation of establishment of protein localization
Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization.
GOC:TermGenie
GO_REF:0000058
PMID:22761445
down regulation of establishment of protein localisation
GOC:TermGenie
down regulation of establishment of protein localization
GOC:TermGenie
down regulation of protein positioning
GOC:TermGenie
down regulation of protein recruitment
GOC:TermGenie
down-regulation of establishment of protein localisation
GOC:TermGenie
down-regulation of establishment of protein localization
GOC:TermGenie
down-regulation of protein positioning
GOC:TermGenie
down-regulation of protein recruitment
GOC:TermGenie
downregulation of establishment of protein localisation
GOC:TermGenie
downregulation of establishment of protein localization
GOC:TermGenie
downregulation of protein positioning
GOC:TermGenie
downregulation of protein recruitment
GOC:TermGenie
negative regulation of establishment of protein localisation
GOC:TermGenie
negative regulation of protein positioning
GOC:TermGenie
negative regulation of protein recruitment
GOC:TermGenie
inhibition of establishment of protein localisation
GOC:TermGenie
inhibition of establishment of protein localization
GOC:TermGenie
inhibition of protein positioning
GOC:TermGenie
inhibition of protein recruitment
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of establishment of protein localization.
mec
2016-02-05T09:59:32Z
positive regulation of establishment of protein localisation
positive regulation of protein positioning
positive regulation of protein recruitment
up regulation of establishment of protein localisation
up regulation of establishment of protein localization
up regulation of protein positioning
up regulation of protein recruitment
up-regulation of establishment of protein localisation
up-regulation of establishment of protein localization
up-regulation of protein positioning
up-regulation of protein recruitment
upregulation of establishment of protein localisation
upregulation of establishment of protein localization
upregulation of protein positioning
upregulation of protein recruitment
activation of establishment of protein localisation
activation of establishment of protein localization
activation of protein positioning
activation of protein recruitment
biological_process
positive regulation of establishment of protein localization
Any process that activates or increases the frequency, rate or extent of establishment of protein localization.
GOC:TermGenie
GO_REF:0000058
PMID:22761445
positive regulation of establishment of protein localisation
GOC:TermGenie
positive regulation of protein positioning
GOC:TermGenie
positive regulation of protein recruitment
GOC:TermGenie
up regulation of establishment of protein localisation
GOC:TermGenie
up regulation of establishment of protein localization
GOC:TermGenie
up regulation of protein positioning
GOC:TermGenie
up regulation of protein recruitment
GOC:TermGenie
up-regulation of establishment of protein localisation
GOC:TermGenie
up-regulation of establishment of protein localization
GOC:TermGenie
up-regulation of protein positioning
GOC:TermGenie
up-regulation of protein recruitment
GOC:TermGenie
upregulation of establishment of protein localisation
GOC:TermGenie
upregulation of establishment of protein localization
GOC:TermGenie
upregulation of protein positioning
GOC:TermGenie
upregulation of protein recruitment
GOC:TermGenie
activation of establishment of protein localisation
GOC:TermGenie
activation of establishment of protein localization
GOC:TermGenie
activation of protein positioning
GOC:TermGenie
activation of protein recruitment
GOC:TermGenie
The vesicle-mediated and directed movement of substances from plastid to vacuole.
tb
2016-02-10T00:14:48Z
biological_process
plastid to vacuolar carboxypeptidase Y vesicle-mediated transport
plastid to vacuole vesicle-mediated transport
The vesicle-mediated and directed movement of substances from plastid to vacuole.
GOC:TermGenie
GO_REF:0000076
PMID:25281689
plastid to vacuolar carboxypeptidase Y vesicle-mediated transport
GOC:TermGenie
Any process that modulates the frequency, rate or extent of endosome organization.
pad
2016-02-22T19:21:01Z
regulation of endosome organisation
biological_process
regulation of endosome organization and biogenesis
regulation of endosome organization
Any process that modulates the frequency, rate or extent of endosome organization.
GOC:PARL
GOC:TermGenie
GOC:pad
GO_REF:0000058
PMID:22511594
regulation of endosome organisation
GOC:TermGenie
regulation of endosome organization and biogenesis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization.
pad
2016-02-22T19:21:08Z
down regulation of endosome organisation
down regulation of endosome organization
down-regulation of endosome organisation
down-regulation of endosome organization
downregulation of endosome organisation
downregulation of endosome organization
negative regulation of endosome organisation
inhibition of endosome organisation
inhibition of endosome organization
biological_process
down regulation of endosome organization and biogenesis
down-regulation of endosome organization and biogenesis
downregulation of endosome organization and biogenesis
inhibition of endosome organization and biogenesis
negative regulation of endosome organization and biogenesis
negative regulation of endosome organization
Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization.
GOC:PARL
GOC:TermGenie
GOC:pad
GO_REF:0000058
PMID:22511594
down regulation of endosome organisation
GOC:TermGenie
down regulation of endosome organization
GOC:TermGenie
down-regulation of endosome organisation
GOC:TermGenie
down-regulation of endosome organization
GOC:TermGenie
downregulation of endosome organisation
GOC:TermGenie
downregulation of endosome organization
GOC:TermGenie
negative regulation of endosome organisation
GOC:TermGenie
inhibition of endosome organisation
GOC:TermGenie
inhibition of endosome organization
GOC:TermGenie
down regulation of endosome organization and biogenesis
GOC:TermGenie
down-regulation of endosome organization and biogenesis
GOC:TermGenie
downregulation of endosome organization and biogenesis
GOC:TermGenie
inhibition of endosome organization and biogenesis
GOC:TermGenie
negative regulation of endosome organization and biogenesis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of endosome organization.
pad
2016-02-22T19:21:16Z
positive regulation of endosome organisation
up regulation of endosome organisation
up regulation of endosome organization
up-regulation of endosome organisation
up-regulation of endosome organization
upregulation of endosome organisation
upregulation of endosome organization
activation of endosome organisation
activation of endosome organization
biological_process
activation of endosome organization and biogenesis
positive regulation of endosome organization and biogenesis
up regulation of endosome organization and biogenesis
up-regulation of endosome organization and biogenesis
upregulation of endosome organization and biogenesis
positive regulation of endosome organization
Any process that activates or increases the frequency, rate or extent of endosome organization.
GOC:PARL
GOC:TermGenie
GOC:pad
GO_REF:0000058
PMID:22511594
positive regulation of endosome organisation
GOC:TermGenie
up regulation of endosome organisation
GOC:TermGenie
up regulation of endosome organization
GOC:TermGenie
up-regulation of endosome organisation
GOC:TermGenie
up-regulation of endosome organization
GOC:TermGenie
upregulation of endosome organisation
GOC:TermGenie
upregulation of endosome organization
GOC:TermGenie
activation of endosome organisation
GOC:TermGenie
activation of endosome organization
GOC:TermGenie
activation of endosome organization and biogenesis
GOC:TermGenie
positive regulation of endosome organization and biogenesis
GOC:TermGenie
up regulation of endosome organization and biogenesis
GOC:TermGenie
up-regulation of endosome organization and biogenesis
GOC:TermGenie
upregulation of endosome organization and biogenesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of mitochondrial translational elongation.
hjd
2016-03-25T17:37:03Z
regulation of mitochondrial translation elongation
biological_process
regulation of mitochondrial translational elongation
Any process that modulates the frequency, rate or extent of mitochondrial translational elongation.
GOC:TermGenie
GO_REF:0000058
PMID:25738458
regulation of mitochondrial translation elongation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation.
hjd
2016-03-25T17:37:13Z
down regulation of mitochondrial translation elongation
down regulation of mitochondrial translational elongation
down-regulation of mitochondrial translation elongation
down-regulation of mitochondrial translational elongation
downregulation of mitochondrial translation elongation
downregulation of mitochondrial translational elongation
negative regulation of mitochondrial translation elongation
inhibition of mitochondrial translation elongation
inhibition of mitochondrial translational elongation
biological_process
negative regulation of mitochondrial translational elongation
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation.
GOC:TermGenie
GO_REF:0000058
PMID:25738458
down regulation of mitochondrial translation elongation
GOC:TermGenie
down regulation of mitochondrial translational elongation
GOC:TermGenie
down-regulation of mitochondrial translation elongation
GOC:TermGenie
down-regulation of mitochondrial translational elongation
GOC:TermGenie
downregulation of mitochondrial translation elongation
GOC:TermGenie
downregulation of mitochondrial translational elongation
GOC:TermGenie
negative regulation of mitochondrial translation elongation
GOC:TermGenie
inhibition of mitochondrial translation elongation
GOC:TermGenie
inhibition of mitochondrial translational elongation
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation.
hjd
2016-03-25T17:37:22Z
positive regulation of mitochondrial translation elongation
up regulation of mitochondrial translation elongation
up regulation of mitochondrial translational elongation
up-regulation of mitochondrial translation elongation
up-regulation of mitochondrial translational elongation
upregulation of mitochondrial translation elongation
upregulation of mitochondrial translational elongation
activation of mitochondrial translation elongation
activation of mitochondrial translational elongation
biological_process
positive regulation of mitochondrial translational elongation
Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation.
GOC:TermGenie
GO_REF:0000058
PMID:25738458
positive regulation of mitochondrial translation elongation
GOC:TermGenie
up regulation of mitochondrial translation elongation
GOC:TermGenie
up regulation of mitochondrial translational elongation
GOC:TermGenie
up-regulation of mitochondrial translation elongation
GOC:TermGenie
up-regulation of mitochondrial translational elongation
GOC:TermGenie
upregulation of mitochondrial translation elongation
GOC:TermGenie
upregulation of mitochondrial translational elongation
GOC:TermGenie
activation of mitochondrial translation elongation
GOC:TermGenie
activation of mitochondrial translational elongation
GOC:TermGenie
Any cellular protein catabolic process that takes place in a lysosome.
bf
2016-04-14T12:50:34Z
cellular protein breakdown in lysosome
cellular protein catabolic process in lysosome
cellular protein catabolism in lysosome
cellular protein degradation in lysosome
lysosomal protein catabolism
lysosomal protein degradation
biological_process
lysosomal proteolysis
proteolysis within lysosome
Also consider annotating to the term 'autophagy ; GO:0006914' or one of its descendants.
lysosomal protein catabolic process
Any cellular protein catabolic process that takes place in a lysosome.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000062
PMID:24334770
cellular protein breakdown in lysosome
GOC:TermGenie
cellular protein catabolism in lysosome
GOC:TermGenie
cellular protein degradation in lysosome
GOC:TermGenie
lysosomal protein catabolism
GOC:bf
lysosomal protein degradation
GOC:bf
lysosomal proteolysis
PMID:24334770
proteolysis within lysosome
GOC:bf
Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis.
tb
2016-04-19T16:12:29Z
down regulation of photosynthesis
down-regulation of photosynthesis
downregulation of photosynthesis
inhibition of photosynthesis
biological_process
negative regulation of photosynthesis
Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis.
GOC:TermGenie
GO_REF:0000058
PMID:7592491
down regulation of photosynthesis
GOC:TermGenie
down-regulation of photosynthesis
GOC:TermGenie
downregulation of photosynthesis
GOC:TermGenie
inhibition of photosynthesis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of photosynthesis.
tb
2016-04-19T16:12:39Z
up regulation of photosynthesis
up-regulation of photosynthesis
upregulation of photosynthesis
activation of photosynthesis
biological_process
positive regulation of photosynthesis
Any process that activates or increases the frequency, rate or extent of photosynthesis.
GOC:TermGenie
GO_REF:0000058
PMID:7592491
up regulation of photosynthesis
GOC:TermGenie
up-regulation of photosynthesis
GOC:TermGenie
upregulation of photosynthesis
GOC:TermGenie
activation of photosynthesis
GOC:TermGenie
Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process.
bf
2016-04-26T12:10:01Z
regulation of cellular protein breakdown in lysosome
regulation of cellular protein catabolic process in lysosome
regulation of cellular protein catabolism in lysosome
regulation of cellular protein degradation in lysosome
regulation of lysosomal protein catabolism
regulation of lysosomal protein degradation
biological_process
regulation of lysosomal proteolysis
regulation of proteolysis within lysosome
regulation of lysosomal protein catabolic process
Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
PMID:23499937
regulation of cellular protein breakdown in lysosome
GOC:TermGenie
regulation of cellular protein catabolic process in lysosome
GOC:TermGenie
regulation of cellular protein catabolism in lysosome
GOC:TermGenie
regulation of cellular protein degradation in lysosome
GOC:TermGenie
regulation of lysosomal protein catabolism
GOC:TermGenie
regulation of lysosomal protein degradation
GOC:TermGenie
regulation of lysosomal proteolysis
GOC:TermGenie
regulation of proteolysis within lysosome
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process.
bf
2016-04-26T12:10:10Z
down regulation of cellular protein breakdown in lysosome
down regulation of cellular protein catabolic process in lysosome
down regulation of cellular protein catabolism in lysosome
down regulation of cellular protein degradation in lysosome
down regulation of lysosomal protein catabolic process
down regulation of lysosomal protein catabolism
down regulation of lysosomal protein degradation
down-regulation of cellular protein breakdown in lysosome
down-regulation of cellular protein catabolic process in lysosome
down-regulation of cellular protein catabolism in lysosome
down-regulation of cellular protein degradation in lysosome
down-regulation of lysosomal protein catabolic process
down-regulation of lysosomal protein catabolism
down-regulation of lysosomal protein degradation
downregulation of cellular protein breakdown in lysosome
downregulation of cellular protein catabolic process in lysosome
downregulation of cellular protein catabolism in lysosome
downregulation of cellular protein degradation in lysosome
downregulation of lysosomal protein catabolic process
downregulation of lysosomal protein catabolism
downregulation of lysosomal protein degradation
negative regulation of cellular protein breakdown in lysosome
negative regulation of cellular protein catabolic process in lysosome
negative regulation of cellular protein catabolism in lysosome
negative regulation of cellular protein degradation in lysosome
negative regulation of lysosomal protein catabolism
negative regulation of lysosomal protein degradation
inhibition of cellular protein breakdown in lysosome
inhibition of cellular protein catabolic process in lysosome
inhibition of cellular protein catabolism in lysosome
inhibition of cellular protein degradation in lysosome
inhibition of lysosomal protein catabolic process
inhibition of lysosomal protein catabolism
inhibition of lysosomal protein degradation
biological_process
down regulation of lysosomal proteolysis
down regulation of proteolysis within lysosome
down-regulation of lysosomal proteolysis
down-regulation of proteolysis within lysosome
downregulation of lysosomal proteolysis
downregulation of proteolysis within lysosome
inhibition of lysosomal proteolysis
inhibition of proteolysis within lysosome
negative regulation of lysosomal proteolysis
negative regulation of proteolysis within lysosome
negative regulation of lysosomal protein catabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
down regulation of cellular protein breakdown in lysosome
GOC:TermGenie
down regulation of cellular protein catabolic process in lysosome
GOC:TermGenie
down regulation of cellular protein catabolism in lysosome
GOC:TermGenie
down regulation of cellular protein degradation in lysosome
GOC:TermGenie
down regulation of lysosomal protein catabolic process
GOC:TermGenie
down regulation of lysosomal protein catabolism
GOC:TermGenie
down regulation of lysosomal protein degradation
GOC:TermGenie
down-regulation of cellular protein breakdown in lysosome
GOC:TermGenie
down-regulation of cellular protein catabolic process in lysosome
GOC:TermGenie
down-regulation of cellular protein catabolism in lysosome
GOC:TermGenie
down-regulation of cellular protein degradation in lysosome
GOC:TermGenie
down-regulation of lysosomal protein catabolic process
GOC:TermGenie
down-regulation of lysosomal protein catabolism
GOC:TermGenie
down-regulation of lysosomal protein degradation
GOC:TermGenie
downregulation of cellular protein breakdown in lysosome
GOC:TermGenie
downregulation of cellular protein catabolic process in lysosome
GOC:TermGenie
downregulation of cellular protein catabolism in lysosome
GOC:TermGenie
downregulation of cellular protein degradation in lysosome
GOC:TermGenie
downregulation of lysosomal protein catabolic process
GOC:TermGenie
downregulation of lysosomal protein catabolism
GOC:TermGenie
downregulation of lysosomal protein degradation
GOC:TermGenie
negative regulation of cellular protein breakdown in lysosome
GOC:TermGenie
negative regulation of cellular protein catabolic process in lysosome
GOC:TermGenie
negative regulation of cellular protein catabolism in lysosome
GOC:TermGenie
negative regulation of cellular protein degradation in lysosome
GOC:TermGenie
negative regulation of lysosomal protein catabolism
GOC:TermGenie
negative regulation of lysosomal protein degradation
GOC:TermGenie
inhibition of cellular protein breakdown in lysosome
GOC:TermGenie
inhibition of cellular protein catabolic process in lysosome
GOC:TermGenie
inhibition of cellular protein catabolism in lysosome
GOC:TermGenie
inhibition of cellular protein degradation in lysosome
GOC:TermGenie
inhibition of lysosomal protein catabolic process
GOC:TermGenie
inhibition of lysosomal protein catabolism
GOC:TermGenie
inhibition of lysosomal protein degradation
GOC:TermGenie
down regulation of lysosomal proteolysis
GOC:TermGenie
down regulation of proteolysis within lysosome
GOC:TermGenie
down-regulation of lysosomal proteolysis
GOC:TermGenie
down-regulation of proteolysis within lysosome
GOC:TermGenie
downregulation of lysosomal proteolysis
GOC:TermGenie
downregulation of proteolysis within lysosome
GOC:TermGenie
inhibition of lysosomal proteolysis
GOC:TermGenie
inhibition of proteolysis within lysosome
GOC:TermGenie
negative regulation of lysosomal proteolysis
GOC:TermGenie
negative regulation of proteolysis within lysosome
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process.
bf
2016-04-26T12:10:19Z
positive regulation of cellular protein breakdown in lysosome
positive regulation of cellular protein catabolic process in lysosome
positive regulation of cellular protein catabolism in lysosome
positive regulation of cellular protein degradation in lysosome
positive regulation of lysosomal protein catabolism
positive regulation of lysosomal protein degradation
up regulation of cellular protein breakdown in lysosome
up regulation of cellular protein catabolic process in lysosome
up regulation of cellular protein catabolism in lysosome
up regulation of cellular protein degradation in lysosome
up regulation of lysosomal protein catabolic process
up regulation of lysosomal protein catabolism
up regulation of lysosomal protein degradation
up-regulation of cellular protein breakdown in lysosome
up-regulation of cellular protein catabolic process in lysosome
up-regulation of cellular protein catabolism in lysosome
up-regulation of cellular protein degradation in lysosome
up-regulation of lysosomal protein catabolic process
up-regulation of lysosomal protein catabolism
up-regulation of lysosomal protein degradation
upregulation of cellular protein breakdown in lysosome
upregulation of cellular protein catabolic process in lysosome
upregulation of cellular protein catabolism in lysosome
upregulation of cellular protein degradation in lysosome
upregulation of lysosomal protein catabolic process
upregulation of lysosomal protein catabolism
upregulation of lysosomal protein degradation
activation of cellular protein breakdown in lysosome
activation of cellular protein catabolic process in lysosome
activation of cellular protein catabolism in lysosome
activation of cellular protein degradation in lysosome
activation of lysosomal protein catabolic process
activation of lysosomal protein catabolism
activation of lysosomal protein degradation
biological_process
activation of lysosomal proteolysis
activation of proteolysis within lysosome
positive regulation of lysosomal proteolysis
positive regulation of proteolysis within lysosome
up regulation of lysosomal proteolysis
up regulation of proteolysis within lysosome
up-regulation of lysosomal proteolysis
up-regulation of proteolysis within lysosome
upregulation of lysosomal proteolysis
upregulation of proteolysis within lysosome
positive regulation of lysosomal protein catabolic process
Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
positive regulation of cellular protein breakdown in lysosome
GOC:TermGenie
positive regulation of cellular protein catabolic process in lysosome
GOC:TermGenie
positive regulation of cellular protein catabolism in lysosome
GOC:TermGenie
positive regulation of cellular protein degradation in lysosome
GOC:TermGenie
positive regulation of lysosomal protein catabolism
GOC:TermGenie
positive regulation of lysosomal protein degradation
GOC:TermGenie
up regulation of cellular protein breakdown in lysosome
GOC:TermGenie
up regulation of cellular protein catabolic process in lysosome
GOC:TermGenie
up regulation of cellular protein catabolism in lysosome
GOC:TermGenie
up regulation of cellular protein degradation in lysosome
GOC:TermGenie
up regulation of lysosomal protein catabolic process
GOC:TermGenie
up regulation of lysosomal protein catabolism
GOC:TermGenie
up regulation of lysosomal protein degradation
GOC:TermGenie
up-regulation of cellular protein breakdown in lysosome
GOC:TermGenie
up-regulation of cellular protein catabolic process in lysosome
GOC:TermGenie
up-regulation of cellular protein catabolism in lysosome
GOC:TermGenie
up-regulation of cellular protein degradation in lysosome
GOC:TermGenie
up-regulation of lysosomal protein catabolic process
GOC:TermGenie
up-regulation of lysosomal protein catabolism
GOC:TermGenie
up-regulation of lysosomal protein degradation
GOC:TermGenie
upregulation of cellular protein breakdown in lysosome
GOC:TermGenie
upregulation of cellular protein catabolic process in lysosome
GOC:TermGenie
upregulation of cellular protein catabolism in lysosome
GOC:TermGenie
upregulation of cellular protein degradation in lysosome
GOC:TermGenie
upregulation of lysosomal protein catabolic process
GOC:TermGenie
upregulation of lysosomal protein catabolism
GOC:TermGenie
upregulation of lysosomal protein degradation
GOC:TermGenie
activation of cellular protein breakdown in lysosome
GOC:TermGenie
activation of cellular protein catabolic process in lysosome
GOC:TermGenie
activation of cellular protein catabolism in lysosome
GOC:TermGenie
activation of cellular protein degradation in lysosome
GOC:TermGenie
activation of lysosomal protein catabolic process
GOC:TermGenie
activation of lysosomal protein catabolism
GOC:TermGenie
activation of lysosomal protein degradation
GOC:TermGenie
activation of lysosomal proteolysis
GOC:TermGenie
activation of proteolysis within lysosome
GOC:TermGenie
positive regulation of lysosomal proteolysis
GOC:TermGenie
positive regulation of proteolysis within lysosome
GOC:TermGenie
up regulation of lysosomal proteolysis
GOC:TermGenie
up regulation of proteolysis within lysosome
GOC:TermGenie
up-regulation of lysosomal proteolysis
GOC:TermGenie
up-regulation of proteolysis within lysosome
GOC:TermGenie
upregulation of lysosomal proteolysis
GOC:TermGenie
upregulation of proteolysis within lysosome
GOC:TermGenie
Any process that modulates the frequency, rate or extent of RNA binding.
bf
2016-06-06T10:20:56Z
biological_process
regulation of RNA binding
Any process that modulates the frequency, rate or extent of RNA binding.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000059
Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding.
bf
2016-06-06T10:21:04Z
down regulation of RNA binding
down-regulation of RNA binding
downregulation of RNA binding
inhibition of RNA binding
biological_process
negative regulation of RNA binding
Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000059
down regulation of RNA binding
GOC:TermGenie
down-regulation of RNA binding
GOC:TermGenie
downregulation of RNA binding
GOC:TermGenie
inhibition of RNA binding
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of RNA binding.
bf
2016-06-06T10:21:12Z
up regulation of RNA binding
up-regulation of RNA binding
upregulation of RNA binding
activation of RNA binding
biological_process
positive regulation of RNA binding
Any process that activates or increases the frequency, rate or extent of RNA binding.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000059
PMID:25116364
up regulation of RNA binding
GOC:TermGenie
up-regulation of RNA binding
GOC:TermGenie
upregulation of RNA binding
GOC:TermGenie
activation of RNA binding
GOC:TermGenie
Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi.
bf
2016-06-20T12:25:29Z
regulation of retrograde (endosome to Golgi) transport
biological_process
regulation of retrograde transport, endosome to Golgi
Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
PMID:23395371
regulation of retrograde (endosome to Golgi) transport
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi.
bf
2016-06-20T12:25:37Z
down regulation of retrograde (endosome to Golgi) transport
down regulation of retrograde transport, endosome to Golgi
down-regulation of retrograde (endosome to Golgi) transport
down-regulation of retrograde transport, endosome to Golgi
downregulation of retrograde (endosome to Golgi) transport
downregulation of retrograde transport, endosome to Golgi
negative regulation of retrograde (endosome to Golgi) transport
inhibition of retrograde (endosome to Golgi) transport
inhibition of retrograde transport, endosome to Golgi
biological_process
negative regulation of retrograde transport, endosome to Golgi
Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
down regulation of retrograde (endosome to Golgi) transport
GOC:TermGenie
down regulation of retrograde transport, endosome to Golgi
GOC:TermGenie
down-regulation of retrograde (endosome to Golgi) transport
GOC:TermGenie
down-regulation of retrograde transport, endosome to Golgi
GOC:TermGenie
downregulation of retrograde (endosome to Golgi) transport
GOC:TermGenie
downregulation of retrograde transport, endosome to Golgi
GOC:TermGenie
negative regulation of retrograde (endosome to Golgi) transport
GOC:TermGenie
inhibition of retrograde (endosome to Golgi) transport
GOC:TermGenie
inhibition of retrograde transport, endosome to Golgi
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi.
bf
2016-06-20T12:25:44Z
positive regulation of retrograde (endosome to Golgi) transport
up regulation of retrograde (endosome to Golgi) transport
up regulation of retrograde transport, endosome to Golgi
up-regulation of retrograde (endosome to Golgi) transport
up-regulation of retrograde transport, endosome to Golgi
upregulation of retrograde (endosome to Golgi) transport
upregulation of retrograde transport, endosome to Golgi
activation of retrograde (endosome to Golgi) transport
activation of retrograde transport, endosome to Golgi
biological_process
positive regulation of retrograde transport, endosome to Golgi
Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi.
GOC:PARL
GOC:TermGenie
GOC:bf
GO_REF:0000058
positive regulation of retrograde (endosome to Golgi) transport
GOC:TermGenie
up regulation of retrograde (endosome to Golgi) transport
GOC:TermGenie
up regulation of retrograde transport, endosome to Golgi
GOC:TermGenie
up-regulation of retrograde (endosome to Golgi) transport
GOC:TermGenie
up-regulation of retrograde transport, endosome to Golgi
GOC:TermGenie
upregulation of retrograde (endosome to Golgi) transport
GOC:TermGenie
upregulation of retrograde transport, endosome to Golgi
GOC:TermGenie
activation of retrograde (endosome to Golgi) transport
GOC:TermGenie
activation of retrograde transport, endosome to Golgi
GOC:TermGenie
The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone.
pr
2016-08-04T14:49:43Z
cilial transition zone assembly
cilial transition zone formation
ciliary transition zone formation
cilium transition zone assembly
cilium transition zone formation
biological_process
ciliary transition zone assembly
The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone.
GOC:TermGenie
GOC:cilia
GO_REF:0000079
PMID:21725307
PMID:23644468
PMID:24448408
PMID:26595381
PMID:26982032
cilial transition zone assembly
GOC:TermGenie
cilial transition zone formation
GOC:TermGenie
ciliary transition zone formation
GOC:TermGenie
cilium transition zone assembly
GOC:TermGenie
cilium transition zone formation
GOC:TermGenie
A protein complex which is capable of GTPase activity.
bhm
2016-08-11T15:34:44Z
HRAS-SOS1 complex
RASH-SOS1 complex
cellular_component
An example of this is HRAS in human (P01112) in PMID:9178006 (inferred from direct assay).
GTPase complex
A protein complex which is capable of GTPase activity.
GOC:TermGenie
GOC:bhm
GO_REF:0000088
PMID:9178006
A protein complex which is capable of peptidase activity.
bhm
2016-08-16T12:49:36Z
protease complex
tryptase complex
cellular_component
An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay).
peptidase complex
A protein complex which is capable of peptidase activity.
GOC:TermGenie
GOC:bhm
GO_REF:0000088
PMID:1689240
A protein complex which is capable of endopeptidase activity.
bhm
2016-08-16T12:52:16Z
cellular_component
An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay).
endopeptidase complex
A protein complex which is capable of endopeptidase activity.
GOC:TermGenie
GOC:bhm
GO_REF:0000088
PMID:1689240
Interacting selectively and non-covalently with a retromer complex.
bc
2016-08-24T14:00:32Z
molecular_function
retromer complex binding
Interacting selectively and non-covalently with a retromer complex.
GOC:PARL
GOC:TermGenie
GOC:bc
PMID:27385586
Any process that modulates the frequency, rate or extent of protein localization to membrane.
bc
2016-09-21T16:20:03Z
regulation of protein localisation in membrane
regulation of protein localization in membrane
biological_process
regulation of protein localization to membrane
Any process that modulates the frequency, rate or extent of protein localization to membrane.
GOC:PARL
GOC:TermGenie
GOC:bc
GO_REF:0000058
PMID:26911690
regulation of protein localisation in membrane
GOC:TermGenie
regulation of protein localization in membrane
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane.
bc
2016-09-21T16:20:10Z
down regulation of protein localisation in membrane
down regulation of protein localization in membrane
down regulation of protein localization to membrane
down-regulation of protein localisation in membrane
down-regulation of protein localization in membrane
down-regulation of protein localization to membrane
downregulation of protein localisation in membrane
downregulation of protein localization in membrane
downregulation of protein localization to membrane
negative regulation of protein localisation in membrane
negative regulation of protein localization in membrane
inhibition of protein localisation in membrane
inhibition of protein localization in membrane
inhibition of protein localization to membrane
biological_process
negative regulation of protein localization to membrane
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane.
GOC:PARL
GOC:TermGenie
GOC:bc
GO_REF:0000058
PMID:26911690
down regulation of protein localisation in membrane
GOC:TermGenie
down regulation of protein localization in membrane
GOC:TermGenie
down regulation of protein localization to membrane
GOC:TermGenie
down-regulation of protein localisation in membrane
GOC:TermGenie
down-regulation of protein localization in membrane
GOC:TermGenie
down-regulation of protein localization to membrane
GOC:TermGenie
downregulation of protein localisation in membrane
GOC:TermGenie
downregulation of protein localization in membrane
GOC:TermGenie
downregulation of protein localization to membrane
GOC:TermGenie
negative regulation of protein localisation in membrane
GOC:TermGenie
negative regulation of protein localization in membrane
GOC:TermGenie
inhibition of protein localisation in membrane
GOC:TermGenie
inhibition of protein localization in membrane
GOC:TermGenie
inhibition of protein localization to membrane
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein localization to membrane.
bc
2016-09-21T16:20:18Z
positive regulation of protein localisation in membrane
positive regulation of protein localization in membrane
up regulation of protein localisation in membrane
up regulation of protein localization in membrane
up regulation of protein localization to membrane
up-regulation of protein localisation in membrane
up-regulation of protein localization in membrane
up-regulation of protein localization to membrane
upregulation of protein localisation in membrane
upregulation of protein localization in membrane
upregulation of protein localization to membrane
activation of protein localisation in membrane
activation of protein localization in membrane
activation of protein localization to membrane
biological_process
positive regulation of protein localization to membrane
Any process that activates or increases the frequency, rate or extent of protein localization to membrane.
GOC:PARL
GOC:TermGenie
GOC:bc
GO_REF:0000058
PMID:26911690
positive regulation of protein localisation in membrane
GOC:TermGenie
positive regulation of protein localization in membrane
GOC:TermGenie
up regulation of protein localisation in membrane
GOC:TermGenie
up regulation of protein localization in membrane
GOC:TermGenie
up regulation of protein localization to membrane
GOC:TermGenie
up-regulation of protein localisation in membrane
GOC:TermGenie
up-regulation of protein localization in membrane
GOC:TermGenie
up-regulation of protein localization to membrane
GOC:TermGenie
upregulation of protein localisation in membrane
GOC:TermGenie
upregulation of protein localization in membrane
GOC:TermGenie
upregulation of protein localization to membrane
GOC:TermGenie
activation of protein localisation in membrane
GOC:TermGenie
activation of protein localization in membrane
GOC:TermGenie
activation of protein localization to membrane
GOC:TermGenie
A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center.
mah
2016-09-28T12:32:16Z
protein localisation in microtubule organizing center
protein localisation to microtubule organizing center
protein localization in microtubule organizing center
biological_process
protein localization to microtubule organizing center
A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center.
GOC:TermGenie
GO_REF:0000087
PMID:19001497
protein localisation in microtubule organizing center
GOC:TermGenie
protein localisation to microtubule organizing center
GOC:TermGenie
protein localization in microtubule organizing center
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum.
rz
2016-10-12T11:37:01Z
regulation of protein localisation in endoplasmic reticulum
regulation of protein localization in ER
regulation of protein localization in endoplasmic reticulum
biological_process
regulation of protein localization to endoplasmic reticulum
Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum.
GOC:TermGenie
GO_REF:0000058
PMID:22768340
regulation of protein localisation in endoplasmic reticulum
GOC:TermGenie
regulation of protein localization in ER
GOC:TermGenie
regulation of protein localization in endoplasmic reticulum
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum.
rz
2016-10-12T11:37:08Z
down regulation of protein localisation in endoplasmic reticulum
down regulation of protein localization in ER
down regulation of protein localization in endoplasmic reticulum
down regulation of protein localization to endoplasmic reticulum
down-regulation of protein localisation in endoplasmic reticulum
down-regulation of protein localization in ER
down-regulation of protein localization in endoplasmic reticulum
down-regulation of protein localization to endoplasmic reticulum
downregulation of protein localisation in endoplasmic reticulum
downregulation of protein localization in ER
downregulation of protein localization in endoplasmic reticulum
downregulation of protein localization to endoplasmic reticulum
negative regulation of protein localisation in endoplasmic reticulum
negative regulation of protein localization in ER
negative regulation of protein localization in endoplasmic reticulum
inhibition of protein localisation in endoplasmic reticulum
inhibition of protein localization in ER
inhibition of protein localization in endoplasmic reticulum
inhibition of protein localization to endoplasmic reticulum
biological_process
negative regulation of protein localization to endoplasmic reticulum
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum.
GOC:TermGenie
GO_REF:0000058
PMID:22768340
down regulation of protein localisation in endoplasmic reticulum
GOC:TermGenie
down regulation of protein localization in ER
GOC:TermGenie
down regulation of protein localization in endoplasmic reticulum
GOC:TermGenie
down regulation of protein localization to endoplasmic reticulum
GOC:TermGenie
down-regulation of protein localisation in endoplasmic reticulum
GOC:TermGenie
down-regulation of protein localization in ER
GOC:TermGenie
down-regulation of protein localization in endoplasmic reticulum
GOC:TermGenie
down-regulation of protein localization to endoplasmic reticulum
GOC:TermGenie
downregulation of protein localisation in endoplasmic reticulum
GOC:TermGenie
downregulation of protein localization in ER
GOC:TermGenie
downregulation of protein localization in endoplasmic reticulum
GOC:TermGenie
downregulation of protein localization to endoplasmic reticulum
GOC:TermGenie
negative regulation of protein localisation in endoplasmic reticulum
GOC:TermGenie
negative regulation of protein localization in ER
GOC:TermGenie
negative regulation of protein localization in endoplasmic reticulum
GOC:TermGenie
inhibition of protein localisation in endoplasmic reticulum
GOC:TermGenie
inhibition of protein localization in ER
GOC:TermGenie
inhibition of protein localization in endoplasmic reticulum
GOC:TermGenie
inhibition of protein localization to endoplasmic reticulum
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum.
rz
2016-10-12T11:37:16Z
positive regulation of protein localisation in endoplasmic reticulum
positive regulation of protein localization in ER
positive regulation of protein localization in endoplasmic reticulum
up regulation of protein localisation in endoplasmic reticulum
up regulation of protein localization in ER
up regulation of protein localization in endoplasmic reticulum
up regulation of protein localization to endoplasmic reticulum
up-regulation of protein localisation in endoplasmic reticulum
up-regulation of protein localization in ER
up-regulation of protein localization in endoplasmic reticulum
up-regulation of protein localization to endoplasmic reticulum
upregulation of protein localisation in endoplasmic reticulum
upregulation of protein localization in ER
upregulation of protein localization in endoplasmic reticulum
upregulation of protein localization to endoplasmic reticulum
activation of protein localisation in endoplasmic reticulum
activation of protein localization in ER
activation of protein localization in endoplasmic reticulum
activation of protein localization to endoplasmic reticulum
biological_process
positive regulation of protein localization to endoplasmic reticulum
Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum.
GOC:TermGenie
GO_REF:0000058
PMID:22768340
positive regulation of protein localisation in endoplasmic reticulum
GOC:TermGenie
positive regulation of protein localization in ER
GOC:TermGenie
positive regulation of protein localization in endoplasmic reticulum
GOC:TermGenie
up regulation of protein localisation in endoplasmic reticulum
GOC:TermGenie
up regulation of protein localization in ER
GOC:TermGenie
up regulation of protein localization in endoplasmic reticulum
GOC:TermGenie
up regulation of protein localization to endoplasmic reticulum
GOC:TermGenie
up-regulation of protein localisation in endoplasmic reticulum
GOC:TermGenie
up-regulation of protein localization in ER
GOC:TermGenie
up-regulation of protein localization in endoplasmic reticulum
GOC:TermGenie
up-regulation of protein localization to endoplasmic reticulum
GOC:TermGenie
upregulation of protein localisation in endoplasmic reticulum
GOC:TermGenie
upregulation of protein localization in ER
GOC:TermGenie
upregulation of protein localization in endoplasmic reticulum
GOC:TermGenie
upregulation of protein localization to endoplasmic reticulum
GOC:TermGenie
activation of protein localisation in endoplasmic reticulum
GOC:TermGenie
activation of protein localization in ER
GOC:TermGenie
activation of protein localization in endoplasmic reticulum
GOC:TermGenie
activation of protein localization to endoplasmic reticulum
GOC:TermGenie
Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly.
hbye
2016-10-14T13:14:57Z
regulation of mitotic nuclear envelope breakdown
regulation of mitotic nuclear envelope catabolism
regulation of mitotic nuclear envelope degradation
biological_process
regulation of mitotic nuclear envelope disassembly
Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly.
GOC:TermGenie
GO_REF:0000058
PMID:18765790
regulation of mitotic nuclear envelope breakdown
GOC:TermGenie
regulation of mitotic nuclear envelope catabolism
GOC:TermGenie
regulation of mitotic nuclear envelope degradation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly.
hbye
2016-10-14T13:15:08Z
down regulation of mitotic nuclear envelope breakdown
down regulation of mitotic nuclear envelope catabolism
down regulation of mitotic nuclear envelope degradation
down regulation of mitotic nuclear envelope disassembly
down-regulation of mitotic nuclear envelope breakdown
down-regulation of mitotic nuclear envelope catabolism
down-regulation of mitotic nuclear envelope degradation
down-regulation of mitotic nuclear envelope disassembly
downregulation of mitotic nuclear envelope breakdown
downregulation of mitotic nuclear envelope catabolism
downregulation of mitotic nuclear envelope degradation
downregulation of mitotic nuclear envelope disassembly
negative regulation of mitotic nuclear envelope breakdown
negative regulation of mitotic nuclear envelope catabolism
negative regulation of mitotic nuclear envelope degradation
inhibition of mitotic nuclear envelope breakdown
inhibition of mitotic nuclear envelope catabolism
inhibition of mitotic nuclear envelope degradation
inhibition of mitotic nuclear envelope disassembly
biological_process
negative regulation of mitotic nuclear envelope disassembly
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly.
GOC:TermGenie
GO_REF:0000058
PMID:18765790
down regulation of mitotic nuclear envelope breakdown
GOC:TermGenie
down regulation of mitotic nuclear envelope catabolism
GOC:TermGenie
down regulation of mitotic nuclear envelope degradation
GOC:TermGenie
down regulation of mitotic nuclear envelope disassembly
GOC:TermGenie
down-regulation of mitotic nuclear envelope breakdown
GOC:TermGenie
down-regulation of mitotic nuclear envelope catabolism
GOC:TermGenie
down-regulation of mitotic nuclear envelope degradation
GOC:TermGenie
down-regulation of mitotic nuclear envelope disassembly
GOC:TermGenie
downregulation of mitotic nuclear envelope breakdown
GOC:TermGenie
downregulation of mitotic nuclear envelope catabolism
GOC:TermGenie
downregulation of mitotic nuclear envelope degradation
GOC:TermGenie
downregulation of mitotic nuclear envelope disassembly
GOC:TermGenie
negative regulation of mitotic nuclear envelope breakdown
GOC:TermGenie
negative regulation of mitotic nuclear envelope catabolism
GOC:TermGenie
negative regulation of mitotic nuclear envelope degradation
GOC:TermGenie
inhibition of mitotic nuclear envelope breakdown
GOC:TermGenie
inhibition of mitotic nuclear envelope catabolism
GOC:TermGenie
inhibition of mitotic nuclear envelope degradation
GOC:TermGenie
inhibition of mitotic nuclear envelope disassembly
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly.
hbye
2016-10-14T13:15:17Z
positive regulation of mitotic nuclear envelope breakdown
positive regulation of mitotic nuclear envelope catabolism
positive regulation of mitotic nuclear envelope degradation
up regulation of mitotic nuclear envelope breakdown
up regulation of mitotic nuclear envelope catabolism
up regulation of mitotic nuclear envelope degradation
up regulation of mitotic nuclear envelope disassembly
up-regulation of mitotic nuclear envelope breakdown
up-regulation of mitotic nuclear envelope catabolism
up-regulation of mitotic nuclear envelope degradation
up-regulation of mitotic nuclear envelope disassembly
upregulation of mitotic nuclear envelope breakdown
upregulation of mitotic nuclear envelope catabolism
upregulation of mitotic nuclear envelope degradation
upregulation of mitotic nuclear envelope disassembly
activation of mitotic nuclear envelope breakdown
activation of mitotic nuclear envelope catabolism
activation of mitotic nuclear envelope degradation
activation of mitotic nuclear envelope disassembly
biological_process
positive regulation of mitotic nuclear envelope disassembly
Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly.
GOC:TermGenie
GO_REF:0000058
PMID:18765790
positive regulation of mitotic nuclear envelope breakdown
GOC:TermGenie
positive regulation of mitotic nuclear envelope catabolism
GOC:TermGenie
positive regulation of mitotic nuclear envelope degradation
GOC:TermGenie
up regulation of mitotic nuclear envelope breakdown
GOC:TermGenie
up regulation of mitotic nuclear envelope catabolism
GOC:TermGenie
up regulation of mitotic nuclear envelope degradation
GOC:TermGenie
up regulation of mitotic nuclear envelope disassembly
GOC:TermGenie
up-regulation of mitotic nuclear envelope breakdown
GOC:TermGenie
up-regulation of mitotic nuclear envelope catabolism
GOC:TermGenie
up-regulation of mitotic nuclear envelope degradation
GOC:TermGenie
up-regulation of mitotic nuclear envelope disassembly
GOC:TermGenie
upregulation of mitotic nuclear envelope breakdown
GOC:TermGenie
upregulation of mitotic nuclear envelope catabolism
GOC:TermGenie
upregulation of mitotic nuclear envelope degradation
GOC:TermGenie
upregulation of mitotic nuclear envelope disassembly
GOC:TermGenie
activation of mitotic nuclear envelope breakdown
GOC:TermGenie
activation of mitotic nuclear envelope catabolism
GOC:TermGenie
activation of mitotic nuclear envelope degradation
GOC:TermGenie
activation of mitotic nuclear envelope disassembly
GOC:TermGenie
Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process.
tb
2016-11-03T20:23:57Z
biological_process
regulation of mitochondrial mRNA catabolic process
Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process.
GOC:TermGenie
GO_REF:0000058
PMID:27122350
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process.
tb
2016-11-03T20:24:05Z
down regulation of mitochondrial mRNA catabolic process
down-regulation of mitochondrial mRNA catabolic process
downregulation of mitochondrial mRNA catabolic process
inhibition of mitochondrial mRNA catabolic process
biological_process
negative regulation of mitochondrial mRNA catabolic process
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process.
GOC:TermGenie
GO_REF:0000058
PMID:27122350
down regulation of mitochondrial mRNA catabolic process
GOC:TermGenie
down-regulation of mitochondrial mRNA catabolic process
GOC:TermGenie
downregulation of mitochondrial mRNA catabolic process
GOC:TermGenie
inhibition of mitochondrial mRNA catabolic process
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process.
tb
2016-11-03T20:24:13Z
up regulation of mitochondrial mRNA catabolic process
up-regulation of mitochondrial mRNA catabolic process
upregulation of mitochondrial mRNA catabolic process
activation of mitochondrial mRNA catabolic process
biological_process
positive regulation of mitochondrial mRNA catabolic process
Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process.
GOC:TermGenie
GO_REF:0000058
PMID:27122350
up regulation of mitochondrial mRNA catabolic process
GOC:TermGenie
up-regulation of mitochondrial mRNA catabolic process
GOC:TermGenie
upregulation of mitochondrial mRNA catabolic process
GOC:TermGenie
activation of mitochondrial mRNA catabolic process
GOC:TermGenie
Any process that modulates the frequency, rate or extent of protein localization to endosome.
bc
2016-11-11T11:19:01Z
regulation of protein localisation in endosome
regulation of protein localization in endosome
biological_process
regulation of protein localization to endosome
Any process that modulates the frequency, rate or extent of protein localization to endosome.
GOC:PARL
GOC:TermGenie
GOC:bc
GO_REF:0000058
PMID:22732145
regulation of protein localisation in endosome
GOC:TermGenie
regulation of protein localization in endosome
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.
bc
2016-11-11T11:19:09Z
down regulation of protein localisation in endosome
down regulation of protein localization in endosome
down regulation of protein localization to endosome
down-regulation of protein localisation in endosome
down-regulation of protein localization in endosome
down-regulation of protein localization to endosome
downregulation of protein localisation in endosome
downregulation of protein localization in endosome
downregulation of protein localization to endosome
negative regulation of protein localisation in endosome
negative regulation of protein localization in endosome
inhibition of protein localisation in endosome
inhibition of protein localization in endosome
inhibition of protein localization to endosome
biological_process
negative regulation of protein localization to endosome
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.
GOC:PARL
GOC:TermGenie
GOC:bc
GO_REF:0000058
PMID:22732145
down regulation of protein localisation in endosome
GOC:TermGenie
down regulation of protein localization in endosome
GOC:TermGenie
down regulation of protein localization to endosome
GOC:TermGenie
down-regulation of protein localisation in endosome
GOC:TermGenie
down-regulation of protein localization in endosome
GOC:TermGenie
down-regulation of protein localization to endosome
GOC:TermGenie
downregulation of protein localisation in endosome
GOC:TermGenie
downregulation of protein localization in endosome
GOC:TermGenie
downregulation of protein localization to endosome
GOC:TermGenie
negative regulation of protein localisation in endosome
GOC:TermGenie
negative regulation of protein localization in endosome
GOC:TermGenie
inhibition of protein localisation in endosome
GOC:TermGenie
inhibition of protein localization in endosome
GOC:TermGenie
inhibition of protein localization to endosome
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of protein localization to endosome.
bc
2016-11-11T11:19:17Z
positive regulation of protein localisation in endosome
positive regulation of protein localization in endosome
up regulation of protein localisation in endosome
up regulation of protein localization in endosome
up regulation of protein localization to endosome
up-regulation of protein localisation in endosome
up-regulation of protein localization in endosome
up-regulation of protein localization to endosome
upregulation of protein localisation in endosome
upregulation of protein localization in endosome
upregulation of protein localization to endosome
activation of protein localisation in endosome
activation of protein localization in endosome
activation of protein localization to endosome
biological_process
positive regulation of protein localization to endosome
Any process that activates or increases the frequency, rate or extent of protein localization to endosome.
GOC:PARL
GOC:TermGenie
GOC:bc
GO_REF:0000058
PMID:22732145
positive regulation of protein localisation in endosome
GOC:TermGenie
positive regulation of protein localization in endosome
GOC:TermGenie
up regulation of protein localisation in endosome
GOC:TermGenie
up regulation of protein localization in endosome
GOC:TermGenie
up regulation of protein localization to endosome
GOC:TermGenie
up-regulation of protein localisation in endosome
GOC:TermGenie
up-regulation of protein localization in endosome
GOC:TermGenie
up-regulation of protein localization to endosome
GOC:TermGenie
upregulation of protein localisation in endosome
GOC:TermGenie
upregulation of protein localization in endosome
GOC:TermGenie
upregulation of protein localization to endosome
GOC:TermGenie
activation of protein localisation in endosome
GOC:TermGenie
activation of protein localization in endosome
GOC:TermGenie
activation of protein localization to endosome
GOC:TermGenie
Any process that modulates the frequency, rate or extent of lysosome organization.
sl
2016-11-11T22:01:04Z
regulation of lysosome organisation
biological_process
regulation of lysosome organization and biogenesis
regulation of lysosome organization
Any process that modulates the frequency, rate or extent of lysosome organization.
GOC:TermGenie
GO_REF:0000058
PMID:25561470
regulation of lysosome organisation
GOC:TermGenie
regulation of lysosome organization and biogenesis
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization.
sl
2016-11-11T22:01:12Z
down regulation of lysosome organisation
down regulation of lysosome organization
down-regulation of lysosome organisation
down-regulation of lysosome organization
downregulation of lysosome organisation
downregulation of lysosome organization
negative regulation of lysosome organisation
inhibition of lysosome organisation
inhibition of lysosome organization
biological_process
down regulation of lysosome organization and biogenesis
down-regulation of lysosome organization and biogenesis
downregulation of lysosome organization and biogenesis
inhibition of lysosome organization and biogenesis
negative regulation of lysosome organization and biogenesis
negative regulation of lysosome organization
Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization.
GOC:TermGenie
GO_REF:0000058
PMID:25561470
down regulation of lysosome organisation
GOC:TermGenie
down regulation of lysosome organization
GOC:TermGenie
down-regulation of lysosome organisation
GOC:TermGenie
down-regulation of lysosome organization
GOC:TermGenie
downregulation of lysosome organisation
GOC:TermGenie
downregulation of lysosome organization
GOC:TermGenie
negative regulation of lysosome organisation
GOC:TermGenie
inhibition of lysosome organisation
GOC:TermGenie
inhibition of lysosome organization
GOC:TermGenie
down regulation of lysosome organization and biogenesis
GOC:TermGenie
down-regulation of lysosome organization and biogenesis
GOC:TermGenie
downregulation of lysosome organization and biogenesis
GOC:TermGenie
inhibition of lysosome organization and biogenesis
GOC:TermGenie
negative regulation of lysosome organization and biogenesis
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of lysosome organization.
sl
2016-11-11T22:01:20Z
positive regulation of lysosome organisation
up regulation of lysosome organisation
up regulation of lysosome organization
up-regulation of lysosome organisation
up-regulation of lysosome organization
upregulation of lysosome organisation
upregulation of lysosome organization
activation of lysosome organisation
activation of lysosome organization
biological_process
activation of lysosome organization and biogenesis
positive regulation of lysosome organization and biogenesis
up regulation of lysosome organization and biogenesis
up-regulation of lysosome organization and biogenesis
upregulation of lysosome organization and biogenesis
positive regulation of lysosome organization
Any process that activates or increases the frequency, rate or extent of lysosome organization.
GOC:TermGenie
GO_REF:0000058
PMID:25561470
positive regulation of lysosome organisation
GOC:TermGenie
up regulation of lysosome organisation
GOC:TermGenie
up regulation of lysosome organization
GOC:TermGenie
up-regulation of lysosome organisation
GOC:TermGenie
up-regulation of lysosome organization
GOC:TermGenie
upregulation of lysosome organisation
GOC:TermGenie
upregulation of lysosome organization
GOC:TermGenie
activation of lysosome organisation
GOC:TermGenie
activation of lysosome organization
GOC:TermGenie
activation of lysosome organization and biogenesis
GOC:TermGenie
positive regulation of lysosome organization and biogenesis
GOC:TermGenie
up regulation of lysosome organization and biogenesis
GOC:TermGenie
up-regulation of lysosome organization and biogenesis
GOC:TermGenie
upregulation of lysosome organization and biogenesis
GOC:TermGenie
The disaggregation of a peroxisome into its constituent components.
pr
2016-11-14T10:09:15Z
biological_process
peroxisomal disassembly
peroxisome disassembly
The disaggregation of a peroxisome into its constituent components.
GOC:TermGenie
GOC:autophagy
GOC:pr
GO_REF:0000079
peroxisomal disassembly
GOC:TermGenie
The disaggregation of a nucleus into its constituent components.
pr
2016-11-14T13:38:57Z
cell nucleus disassembly
biological_process
nucleus disassembly
The disaggregation of a nucleus into its constituent components.
GOC:TermGenie
GOC:autophagy
GOC:pr
GO_REF:0000079
cell nucleus disassembly
GOC:TermGenie
The disaggregation of a lipid particle into its constituent components.
pr
2016-11-14T13:39:06Z
adiposome disassembly
lipid body disassembly
lipid droplet reserve breakdown
lipid particle disassembly
biological_process
lipid droplet disassembly
The disaggregation of a lipid particle into its constituent components.
GOC:TermGenie
GOC:autophagy
GOC:pr
GO_REF:0000079
adiposome disassembly
GOC:TermGenie
lipid body disassembly
GOC:TermGenie
lipid droplet reserve breakdown
PMID:30003614
lipid particle disassembly
GOC:TermGenie
The disaggregation of an endoplasmic reticulum into its constituent components.
pr
2016-11-14T13:39:14Z
ER disassembly
biological_process
endoplasmic reticulum disassembly
The disaggregation of an endoplasmic reticulum into its constituent components.
GOC:TermGenie
GOC:autophagy
GOC:pr
GO_REF:0000079
ER disassembly
GOC:TermGenie
Any microtubule bundle that is part of a cytoplasm.
mah
2016-11-24T16:52:02Z
microtubule bundle of cytoplasm
microtubule fascicle of cytoplasm
cellular_component
cytoplasmic microtubule bundle
Any microtubule bundle that is part of a cytoplasm.
GOC:TermGenie
GO_REF:0000064
PMID:11007487
PMID:26124291
microtubule bundle of cytoplasm
GOC:TermGenie
microtubule fascicle of cytoplasm
GOC:TermGenie
Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport.
pgarmiri
2016-12-09T13:46:13Z
biological_process
regulation of endosome to plasma membrane protein transport
Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport.
GOC:TermGenie
GO_REF:0000058
PMID:22869721
Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport.
pgarmiri
2016-12-09T13:46:21Z
down regulation of endosome to plasma membrane protein transport
down-regulation of endosome to plasma membrane protein transport
downregulation of endosome to plasma membrane protein transport
inhibition of endosome to plasma membrane protein transport
biological_process
negative regulation of endosome to plasma membrane protein transport
Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport.
GOC:TermGenie
GO_REF:0000058
PMID:22869721
down regulation of endosome to plasma membrane protein transport
GOC:TermGenie
down-regulation of endosome to plasma membrane protein transport
GOC:TermGenie
downregulation of endosome to plasma membrane protein transport
GOC:TermGenie
inhibition of endosome to plasma membrane protein transport
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport.
pgarmiri
2016-12-09T13:46:30Z
up regulation of endosome to plasma membrane protein transport
up-regulation of endosome to plasma membrane protein transport
upregulation of endosome to plasma membrane protein transport
activation of endosome to plasma membrane protein transport
biological_process
positive regulation of endosome to plasma membrane protein transport
Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport.
GOC:TermGenie
GO_REF:0000058
PMID:22869721
up regulation of endosome to plasma membrane protein transport
GOC:TermGenie
up-regulation of endosome to plasma membrane protein transport
GOC:TermGenie
upregulation of endosome to plasma membrane protein transport
GOC:TermGenie
activation of endosome to plasma membrane protein transport
GOC:TermGenie
A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule.
mah11
2016-12-12T15:31:07Z
protein localisation to cytoplasmic microtubule
biological_process
protein localization to cytoplasmic microtubule
A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule.
GOC:TermGenie
GO_REF:0000087
PMID:15177031
protein localisation to cytoplasmic microtubule
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation.
hbye
2017-01-17T12:00:56Z
down regulation of microtubule nucleation
down-regulation of microtubule nucleation
downregulation of microtubule nucleation
inhibition of microtubule nucleation
biological_process
negative regulation of microtubule nucleation
Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation.
GOC:TermGenie
GO_REF:0000058
PMID:27689799
down regulation of microtubule nucleation
GOC:TermGenie
down-regulation of microtubule nucleation
GOC:TermGenie
downregulation of microtubule nucleation
GOC:TermGenie
inhibition of microtubule nucleation
GOC:TermGenie
Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress.
BarbaraCzub
2017-02-01T11:42:55Z
regulation of ER stress response
regulation of cellular response to endoplasmic reticulum stress
regulation of response to ER stress
biological_process
regulation of response to endoplasmic reticulum stress
Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress.
GOC:TermGenie
GOC:aruk
GOC:bc
GO_REF:0000058
PMID:21803450
regulation of ER stress response
GOC:TermGenie
regulation of cellular response to endoplasmic reticulum stress
GOC:TermGenie
regulation of response to ER stress
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress.
BarbaraCzub
2017-02-01T11:43:03Z
positive regulation of ER stress response
positive regulation of cellular response to endoplasmic reticulum stress
positive regulation of response to ER stress
up regulation of ER stress response
up regulation of cellular response to endoplasmic reticulum stress
up regulation of response to ER stress
up regulation of response to endoplasmic reticulum stress
up-regulation of ER stress response
up-regulation of cellular response to endoplasmic reticulum stress
up-regulation of response to ER stress
up-regulation of response to endoplasmic reticulum stress
upregulation of ER stress response
upregulation of cellular response to endoplasmic reticulum stress
upregulation of response to ER stress
upregulation of response to endoplasmic reticulum stress
activation of ER stress response
activation of cellular response to endoplasmic reticulum stress
activation of response to ER stress
activation of response to endoplasmic reticulum stress
biological_process
positive regulation of response to endoplasmic reticulum stress
Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress.
GOC:TermGenie
GOC:aruk
GOC:bc
GO_REF:0000058
PMID:21803450
positive regulation of ER stress response
GOC:TermGenie
positive regulation of cellular response to endoplasmic reticulum stress
GOC:TermGenie
positive regulation of response to ER stress
GOC:TermGenie
up regulation of ER stress response
GOC:TermGenie
up regulation of cellular response to endoplasmic reticulum stress
GOC:TermGenie
up regulation of response to ER stress
GOC:TermGenie
up regulation of response to endoplasmic reticulum stress
GOC:TermGenie
up-regulation of ER stress response
GOC:TermGenie
up-regulation of cellular response to endoplasmic reticulum stress
GOC:TermGenie
up-regulation of response to ER stress
GOC:TermGenie
up-regulation of response to endoplasmic reticulum stress
GOC:TermGenie
upregulation of ER stress response
GOC:TermGenie
upregulation of cellular response to endoplasmic reticulum stress
GOC:TermGenie
upregulation of response to ER stress
GOC:TermGenie
upregulation of response to endoplasmic reticulum stress
GOC:TermGenie
activation of ER stress response
GOC:TermGenie
activation of cellular response to endoplasmic reticulum stress
GOC:TermGenie
activation of response to ER stress
GOC:TermGenie
activation of response to endoplasmic reticulum stress
GOC:TermGenie
Any process that modulates the frequency, rate or extent of lipid localization.
rozaru
2017-02-21T12:12:22Z
regulation of lipid localisation
biological_process
regulation of lipid localization
Any process that modulates the frequency, rate or extent of lipid localization.
GOC:TermGenie
GO_REF:0000058
PMID:17564681
regulation of lipid localisation
GOC:TermGenie
Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization.
rozaru
2017-02-21T12:12:41Z
down regulation of lipid localisation
down regulation of lipid localization
down-regulation of lipid localisation
down-regulation of lipid localization
downregulation of lipid localisation
downregulation of lipid localization
negative regulation of lipid localisation
inhibition of lipid localisation
inhibition of lipid localization
biological_process
negative regulation of lipid localization
Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization.
GOC:TermGenie
GO_REF:0000058
PMID:17564681
down regulation of lipid localisation
GOC:TermGenie
down regulation of lipid localization
GOC:TermGenie
down-regulation of lipid localisation
GOC:TermGenie
down-regulation of lipid localization
GOC:TermGenie
downregulation of lipid localisation
GOC:TermGenie
downregulation of lipid localization
GOC:TermGenie
negative regulation of lipid localisation
GOC:TermGenie
inhibition of lipid localisation
GOC:TermGenie
inhibition of lipid localization
GOC:TermGenie
Any process that activates or increases the frequency, rate or extent of lipid localization.
rozaru
2017-02-21T12:12:49Z
positive regulation of lipid localisation
up regulation of lipid localisation
up regulation of lipid localization
up-regulation of lipid localisation
up-regulation of lipid localization
upregulation of lipid localisation
upregulation of lipid localization
activation of lipid localisation
activation of lipid localization
biological_process
positive regulation of lipid localization
Any process that activates or increases the frequency, rate or extent of lipid localization.
GOC:TermGenie
GO_REF:0000058
PMID:17564681
positive regulation of lipid localisation
GOC:TermGenie
up regulation of lipid localisation
GOC:TermGenie
up regulation of lipid localization
GOC:TermGenie
up-regulation of lipid localisation
GOC:TermGenie
up-regulation of lipid localization
GOC:TermGenie
upregulation of lipid localisation
GOC:TermGenie
upregulation of lipid localization
GOC:TermGenie
activation of lipid localisation
GOC:TermGenie
activation of lipid localization
GOC:TermGenie
A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet.
sart
2013-02-15T12:40:57Z
protein localisation to adiposome
protein localisation to lipid body
protein localisation to lipid droplet
protein localisation to lipid particle
protein localization to adiposome
protein localization to lipid body
protein localization to lipid particle
biological_process
protein localization to lipid droplet
A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet.
GOC:sart
PMID:22505614
The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins.
sp
2013-06-18T10:52:50Z
biological_process
retrograde transport, endosome to plasma membrane
The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins.
PMID:23563491
A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.
https://github.com/geneontology/go-ontology/issues/14690
mah
2013-08-23T15:01:16Z
GO:0032066
protein localisation to nucleoplasm
biological_process
nucleolus to nucleoplasm transport
protein localization to nucleoplasm
A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.
GOC:mah
PMID:22918952
protein localisation to nucleoplasm
GOC:mah
Any protein complex that possesses oxidoreductase activity.
bhm
2013-10-07T08:24:47Z
oxidation-reduction complex
redox complex
cellular_component
oxidoreductase complex
Any protein complex that possesses oxidoreductase activity.
GOC:bhm
PMID:18982432
A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).
bhm
2013-11-12T13:20:12Z
cellular_component
transferase complex
A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).
GOC:bhm
PMID:16540464
A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.
bhm
2014-03-26T14:23:27Z
cellular_component
An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay).
transporter complex
A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.
GOC:bhm
PMID:15449578
Any process that modulates the frequency, rate or extent of cytoplasmic translational termination.
vw
2014-12-10T15:48:55Z
biological_process
regulation of cytoplasmic translational termination
Any process that modulates the frequency, rate or extent of cytoplasmic translational termination.
PMID:11570975
The joining of two lipid bilayers that surround the mitochondria.
vw
2015-01-21T06:58:18Z
biological_process
mitochondrial membrane fusion
The joining of two lipid bilayers that surround the mitochondria.
PMID:12052774
A process in which a protein is transported to, or maintained in, the cell periphery.
2015-06-18T22:37:39Z
biological_process
protein localization to cell periphery
A process in which a protein is transported to, or maintained in, the cell periphery.
PMID:18216290
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.
sl
2015-06-24T17:54:13Z
response to double-stranded DNA
biological_process
response to dsDNA
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.
PMID:10051633
Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
sl
2015-08-25T17:30:06Z
sequence-specific dsDNA binding
molecular_function
sequence-specific double-stranded DNA binding
Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
GOC:dos
GOC:sl
A macromolecular complex containing both protein and RNA molecules.
pr
2015-11-19T12:26:37Z
GO:0030529
GO:1990903
Wikipedia:Ribonucleoprotein
RNA-protein complex
RNP
protein-RNA complex
ribonucleoprotein complex
extracellular ribonucleoprotein complex
intracellular ribonucleoprotein complex
cellular_component
ribonucleoprotein complex
A macromolecular complex containing both protein and RNA molecules.
GOC:vesicles
Any process that modulates the frequency, rate or extent of multicellular organismal development.
tanyaberardini
2010-08-05T11:25:59Z
biological_process
regulation of multicellular organismal development
Any process that modulates the frequency, rate or extent of multicellular organismal development.
GOC:obol
Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process.
tanyaberardini
2010-09-15T08:55:45Z
regulation of cellular biopolymer biosynthetic process
regulation of cellular macromolecule anabolism
regulation of cellular macromolecule biosynthesis
regulation of cellular macromolecule formation
regulation of cellular macromolecule synthesis
biological_process
regulation of cellular macromolecule biosynthetic process
Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process.
GOC:obol
regulation of cellular biopolymer biosynthetic process
GOC:obol
regulation of cellular macromolecule anabolism
GOC:obol
regulation of cellular macromolecule biosynthesis
GOC:obol
regulation of cellular macromolecule formation
GOC:obol
regulation of cellular macromolecule synthesis
GOC:obol
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process.
tanyaberardini
2010-09-15T08:55:48Z
negative regulation of cellular biopolymer biosynthetic process
negative regulation of cellular macromolecule anabolism
negative regulation of cellular macromolecule biosynthesis
negative regulation of cellular macromolecule formation
negative regulation of cellular macromolecule synthesis
biological_process
negative regulation of cellular macromolecule biosynthetic process
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process.
GOC:obol
negative regulation of cellular biopolymer biosynthetic process
GOC:obol
negative regulation of cellular macromolecule anabolism
GOC:obol
negative regulation of cellular macromolecule biosynthesis
GOC:obol
negative regulation of cellular macromolecule formation
GOC:obol
negative regulation of cellular macromolecule synthesis
GOC:obol
Any process that modulates the frequency, rate or extent of cell motility.
midori
2010-10-01T09:41:21Z
regulation of cell locomotion
regulation of movement of a cell
biological_process
regulation of cell movement
regulation of cell motility
Any process that modulates the frequency, rate or extent of cell motility.
GOC:mah
regulation of cell locomotion
GOC:obol
regulation of movement of a cell
GOC:obol
regulation of cell movement
GOC:obol
Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.
midori
2010-10-01T09:41:26Z
negative regulation of cell locomotion
negative regulation of movement of a cell
biological_process
negative regulation of cell movement
negative regulation of cell motility
Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.
GOC:mah
negative regulation of cell locomotion
GOC:obol
negative regulation of movement of a cell
GOC:obol
negative regulation of cell movement
GOC:obol
Any process that activates or increases the frequency, rate or extent of cell motility.
midori
2010-10-01T09:41:30Z
positive regulation of cell locomotion
positive regulation of movement of a cell
biological_process
positive regulation of cell movement
positive regulation of cell motility
Any process that activates or increases the frequency, rate or extent of cell motility.
GOC:mah
positive regulation of cell locomotion
GOC:obol
positive regulation of movement of a cell
GOC:obol
positive regulation of cell movement
GOC:obol
Any process that modulates the frequency, rate or extent of rRNA processing.
midori
2010-11-10T12:11:29Z
biological_process
regulation of 35S primary transcript processing
regulation of rRNA processing
Any process that modulates the frequency, rate or extent of rRNA processing.
GOC:mah
regulation of 35S primary transcript processing
GOC:obol
Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.
midori
2010-11-10T12:11:33Z
biological_process
negative regulation of 35S primary transcript processing
negative regulation of rRNA processing
Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.
GOC:mah
negative regulation of 35S primary transcript processing
GOC:obol
Any process that activates or increases the frequency, rate or extent of rRNA processing.
midori
2010-11-10T12:11:36Z
biological_process
positive regulation of 35S primary transcript processing
positive regulation of rRNA processing
Any process that activates or increases the frequency, rate or extent of rRNA processing.
GOC:mah
positive regulation of 35S primary transcript processing
GOC:obol
Any process that modulates the frequency, rate or extent of tRNA processing.
midori
2010-11-10T12:15:08Z
regulation of tRNA maturation
biological_process
regulation of tRNA processing
Any process that modulates the frequency, rate or extent of tRNA processing.
GOC:mah
regulation of tRNA maturation
GOC:obol
Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing.
midori
2010-11-10T12:15:13Z
negative regulation of tRNA maturation
biological_process
negative regulation of tRNA processing
Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing.
GOC:mah
negative regulation of tRNA maturation
GOC:obol
Any process that activates or increases the frequency, rate or extent of tRNA processing.
midori
2010-11-10T12:15:17Z
positive regulation of tRNA maturation
biological_process
positive regulation of tRNA processing
Any process that activates or increases the frequency, rate or extent of tRNA processing.
GOC:mah
positive regulation of tRNA maturation
GOC:obol
Any process that modulates the frequency, rate or extent of reproductive process.
midori
2010-11-10T02:44:02Z
biological_process
regulation of reproductive process
Any process that modulates the frequency, rate or extent of reproductive process.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process.
midori
2010-11-10T02:44:05Z
biological_process
negative regulation of reproductive process
Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process.
GOC:mah
Any process that activates or increases the frequency, rate or extent of reproductive process.
midori
2010-11-10T02:44:08Z
biological_process
positive regulation of reproductive process
Any process that activates or increases the frequency, rate or extent of reproductive process.
GOC:mah
Any process that modulates the frequency, rate or extent of DNA biosynthetic process.
yaf
2010-12-08T04:48:15Z
regulation of DNA anabolism
regulation of DNA biosynthesis
regulation of DNA formation
regulation of DNA synthesis
biological_process
regulation of DNA biosynthetic process
Any process that modulates the frequency, rate or extent of DNA biosynthetic process.
GOC:obol
regulation of DNA anabolism
GOC:obol
regulation of DNA biosynthesis
GOC:obol
regulation of DNA formation
GOC:obol
regulation of DNA synthesis
GOC:obol
Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.
yaf
2010-12-08T04:48:20Z
negative regulation of DNA anabolism
negative regulation of DNA biosynthesis
negative regulation of DNA formation
negative regulation of DNA synthesis
biological_process
negative regulation of DNA biosynthetic process
Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.
GOC:obol
negative regulation of DNA anabolism
GOC:obol
negative regulation of DNA biosynthesis
GOC:obol
negative regulation of DNA formation
GOC:obol
negative regulation of DNA synthesis
GOC:obol
Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process.
vw
2010-12-10T11:54:19Z
regulation of amino acid biosynthetic process
regulation of cellular amino acid anabolism
regulation of cellular amino acid biosynthesis
regulation of cellular amino acid formation
regulation of cellular amino acid synthesis
biological_process
regulation of cellular amino acid biosynthetic process
Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process.
GOC:obol
regulation of amino acid biosynthetic process
GOC:obol
regulation of cellular amino acid anabolism
GOC:obol
regulation of cellular amino acid biosynthesis
GOC:obol
regulation of cellular amino acid formation
GOC:obol
regulation of cellular amino acid synthesis
GOC:obol
Any process that stops, prevents or reduces the frequency, rate or extent of cellular amino acid biosynthetic process.
vw
2010-12-10T11:54:23Z
negative regulation of amino acid biosynthetic process
negative regulation of cellular amino acid anabolism
negative regulation of cellular amino acid biosynthesis
negative regulation of cellular amino acid formation
negative regulation of cellular amino acid synthesis
biological_process
negative regulation of cellular amino acid biosynthetic process
Any process that stops, prevents or reduces the frequency, rate or extent of cellular amino acid biosynthetic process.
GOC:obol
negative regulation of amino acid biosynthetic process
GOC:obol
negative regulation of cellular amino acid anabolism
GOC:obol
negative regulation of cellular amino acid biosynthesis
GOC:obol
negative regulation of cellular amino acid formation
GOC:obol
negative regulation of cellular amino acid synthesis
GOC:obol
Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process.
vw
2010-12-10T11:54:27Z
positive regulation of amino acid biosynthetic process
positive regulation of cellular amino acid anabolism
positive regulation of cellular amino acid biosynthesis
positive regulation of cellular amino acid formation
positive regulation of cellular amino acid synthesis
biological_process
positive regulation of cellular amino acid biosynthetic process
Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process.
GOC:obol
positive regulation of amino acid biosynthetic process
GOC:obol
positive regulation of cellular amino acid anabolism
GOC:obol
positive regulation of cellular amino acid biosynthesis
GOC:obol
positive regulation of cellular amino acid formation
GOC:obol
positive regulation of cellular amino acid synthesis
GOC:obol
Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.
yaf
2011-04-04T10:01:20Z
positive regulation of DNA anabolism
positive regulation of DNA biosynthesis
positive regulation of DNA formation
positive regulation of DNA synthesis
biological_process
positive regulation of DNA biosynthetic process
Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.
GOC:obol
positive regulation of DNA anabolism
GOC:obol
positive regulation of DNA biosynthesis
GOC:obol
positive regulation of DNA formation
GOC:obol
positive regulation of DNA synthesis
GOC:obol
Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding.
yaf
2011-05-09T03:28:11Z
biological_process
regulation of transcription regulatory region DNA binding
Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding.
GOC:obol
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
yaf
2011-05-09T03:28:14Z
biological_process
negative regulation of transcription regulatory region DNA binding
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
GOC:obol
Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.
yaf
2011-05-09T03:28:17Z
biological_process
positive regulation of transcription regulatory region DNA binding
Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.
GOC:obol
Any process that modulates the frequency, rate or extent of cytoplasmic translation.
vw
2011-06-20T10:39:19Z
biological_process
regulation of cytoplasmic translation
Any process that modulates the frequency, rate or extent of cytoplasmic translation.
GOC:obol
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.
vw
2011-06-20T10:39:23Z
biological_process
negative regulation of cytoplasmic translation
Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.
GOC:obol
Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.
vw
2011-06-20T10:39:26Z
biological_process
positive regulation of cytoplasmic translation
Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.
GOC:obol
The process in which a signal is passed on to downstream components located at the endosome. Endosomes can provide important intracellular signaling platforms and provide spatial and temporal control over signal transduction.
rfoulger
2011-07-01T03:45:12Z
endosome-based signaling
signaling from endosome
biological_process
signaling cascade in endosome
signaling pathway in endosome
signalling cascade in endosome
signalling pathway in endosome
endosomal signal transduction
The process in which a signal is passed on to downstream components located at the endosome. Endosomes can provide important intracellular signaling platforms and provide spatial and temporal control over signal transduction.
GOC:bf
GOC:signaling
PMID:15084302
PMID:17662591
endosome-based signaling
PMID:17662591
signaling from endosome
PMID:17662591
signaling cascade in endosome
GOC:obol
signaling pathway in endosome
GOC:obol
signalling cascade in endosome
GOC:obol
signalling pathway in endosome
GOC:obol
Any process that modulates the frequency, rate or extent of RNA biosynthetic process.
dph
2011-10-17T11:36:25Z
regulation of RNA anabolism
regulation of RNA biosynthesis
regulation of RNA formation
regulation of RNA synthesis
biological_process
regulation of RNA biosynthetic process
Any process that modulates the frequency, rate or extent of RNA biosynthetic process.
GOC:dph
regulation of RNA anabolism
GOC:obol
regulation of RNA biosynthesis
GOC:obol
regulation of RNA formation
GOC:obol
regulation of RNA synthesis
GOC:obol
Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.
yaf
2011-12-02T02:01:20Z
negative regulation of chromosome organisation
biological_process
negative regulation of chromosome organization and biogenesis
negative regulation of maintenance of genome integrity
negative regulation of nuclear genome maintenance
negative regulation of chromosome organization
Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.
GOC:obol
negative regulation of chromosome organisation
GOC:obol
negative regulation of chromosome organization and biogenesis
GOC:obol
negative regulation of maintenance of genome integrity
GOC:obol
negative regulation of nuclear genome maintenance
GOC:obol
Any process that activates or increases the frequency, rate or extent of chromosome organization.
yaf
2011-12-02T02:01:26Z
positive regulation of chromosome organisation
biological_process
positive regulation of chromosome organization and biogenesis
positive regulation of maintenance of genome integrity
positive regulation of nuclear genome maintenance
positive regulation of chromosome organization
Any process that activates or increases the frequency, rate or extent of chromosome organization.
GOC:obol
positive regulation of chromosome organisation
GOC:obol
positive regulation of chromosome organization and biogenesis
GOC:obol
positive regulation of maintenance of genome integrity
GOC:obol
positive regulation of nuclear genome maintenance
GOC:obol
measurement unit label
Examples of measurement unit labels are liters, inches, weight per volume.
A data item label that denotes a unit of measure.
2009-03-16: provenance: a term measurement unit was
proposed for OBI (OBI_0000176) , edited by Chris Stoeckert and
Cristian Cocos, and subsequently moved to IAO where the objective for
which the original term was defined was satisfied with the definition
of this, different, term.
2009-03-16: review of this term done during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify this definition please notify OBI.
PERSON: Alan Ruttenberg
PERSON: Melanie Courtot
http://purl.obolibrary.org/obo/obi.owl
measurement unit label
data item label
An information content entity that is part of some data item and is used to partially define the denotation of that data item.
http://www.golovchenko.org/cgi-bin/wnsearch?q=label#4n
GROUP: IAO
datum label
9/22/11 BP: changed the rdfs:label for this class from 'label' to 'datum label' to convey that this class is not intended to cover all kinds of labels (stickers, radiolabels, etc.), and not even all kind of textual labels, but rather the kind of labels occuring in a datum.
http://purl.obolibrary.org/obo/obi.owl
data item label
GC_ID:1
ncbi_taxonomy
Teleostomi
NCBITaxon:40673
GC_ID:1
bony vertebrates
ncbi_taxonomy
Euteleostomi
bony vertebrates
GC_ID:1
ncbi_taxonomy
Ecdysozoa
GC_ID:11
PMID:11321122
PMID:11542017
PMID:11837318
PMID:16280474
PMID:26654112
PMID:29458499
purple bacteria
purple bacteria and relatives
purple non-sulfur bacteria
purple photosynthetic bacteria
purple photosynthetic bacteria and relatives
ncbi_taxonomy
Alphaproteobacteraeota
Alphaproteobacteriota
proteobacteria
Proteobacteria
purple bacteria
purple bacteria and relatives
purple non-sulfur bacteria
purple photosynthetic bacteria
purple photosynthetic bacteria and relatives
Alphaproteobacteraeota
Alphaproteobacteriota
proteobacteria
GC_ID:11
PMID:16280474
PMID:23334881
ncbi_taxonomy
Proteobacteria gamma subdivision
Purple bacteria, gamma subdivision
g-proteobacteria
gamma proteobacteria
gamma subdivision
gamma subgroup
Gammaproteobacteria
Proteobacteria gamma subdivision
Purple bacteria, gamma subdivision
g-proteobacteria
gamma proteobacteria
gamma subdivision
gamma subgroup
GC_ID:1
ncbi_taxonomy
Dipnotetrapodomorpha
GC_ID:1
PMID:11743200
PMID:11791233
ncbi_taxonomy
Boreotheria
Boreoeutheria
Boreotheria
GC_ID:1
PMID:10874751
PMID:11557979
ncbi_taxonomy
Pancrustacea
GC_ID:1
PMID:11557979
PMID:9727836
mandibulates
ncbi_taxonomy
Mandibulata
mandibulates
GC_ID:11
PMID:10425795
PMID:10425796
PMID:10425797
PMID:10490293
PMID:10843050
PMID:10939651
PMID:10939673
PMID:10939677
PMID:11211268
PMID:11321083
PMID:11321113
PMID:11411719
PMID:11540071
PMID:11542017
PMID:11542087
PMID:11760965
PMID:12054223
PMID:2112744
PMID:270744
PMID:7520741
PMID:8123559
PMID:8186100
PMID:8590690
PMID:9103655
PMID:9336922
eubacteria
ncbi_taxonomy
Monera
Procaryotae
Prokaryota
Prokaryotae
bacteria
prokaryote
prokaryotes
Bacteria
eubacteria
Monera
Procaryotae
Prokaryota
Prokaryotae
bacteria
prokaryote
prokaryotes
GC_ID:1
ncbi_taxonomy
Homo/Pan/Gorilla group
Homininae
Homo/Pan/Gorilla group
GC_ID:1
PMID:23020233
PMID:30257078
eucaryotes
eukaryotes
ncbi_taxonomy
Eucarya
Eucaryotae
Eukarya
Eukaryotae
eukaryotes
Eukaryota
eucaryotes
eukaryotes
Eucarya
Eucaryotae
Eukarya
Eukaryotae
eukaryotes
GC_ID:1
PMID:11214319
PMID:12082125
PMID:12878460
PMID:15522813
ncbi_taxonomy
Euarchontoglires
GC_ID:1
ncbi_taxonomy
Anthropoidea
Simiiformes
Anthropoidea
GC_ID:1
ape
apes
ncbi_taxonomy
Hominoidea
ape
apes
GC_ID:1
ncbi_taxonomy
Sophophora
GC_ID:1
ncbi_taxonomy
melanogaster group
GC_ID:1
ncbi_taxonomy
melanogaster subgroup
GC_ID:1
tetrapods
ncbi_taxonomy
Tetrapoda
tetrapods
GC_ID:1
amniotes
ncbi_taxonomy
Amniota
amniotes
GC_ID:1
Theria
ncbi_taxonomy
Theria <mammals>
Theria
GC_ID:1
ncbi_taxonomy
Fungi/Metazoa group
opisthokonts
Opisthokonta
Fungi/Metazoa group
opisthokonts
GC_ID:1
metazoans
multicellular animals
ncbi_taxonomy
Animalia
animals
Metazoa
metazoans
multicellular animals
Animalia
animals
GC_ID:1
ncbi_taxonomy
Bilateria
GC_ID:1
ncbi_taxonomy
Protostomia
GC_ID:1
ncbi_taxonomy
Neoptera
GC_ID:1
ncbi_taxonomy
Endopterygota
Holometabola
Endopterygota
GC_ID:1
deuterostomes
ncbi_taxonomy
Deuterostomia
deuterostomes
GC_ID:1
ncbi_taxonomy
Haplorrhini
GC_ID:1
mammals
ncbi_taxonomy
mammals
Mammalia
mammals
mammals
NCBITaxon:43732
GC_ID:1
ncbi_taxonomy
Asilomorpha
Muscomorpha
Asilomorpha
GC_ID:1
ncbi_taxonomy
Schizophora
GC_ID:1
ncbi_taxonomy
Acalyptratae
GC_ID:1
ncbi_taxonomy
Ephydroidea
GC_ID:1
ncbi_taxonomy
Drosophilinae
GC_ID:1
ncbi_taxonomy
Drosophilini
GC_ID:1
ncbi_taxonomy
Cyclorrhapha
GC_ID:1
ncbi_taxonomy
Eremoneura
GC_ID:1
true insects
ncbi_taxonomy
Insecta
true insects
GC_ID:11
PMID:10555323
PMID:10555334
PMID:16166704
PMID:27620848
ncbi_taxonomy
Enterobacteraceae
gamma-3 proteobacteria
Enterobacteriaceae
Enterobacteraceae
gamma-3 proteobacteria
GC_ID:11
PMID:19700542
ncbi_taxonomy
Escherichia
NCBITaxon:1637691
NCBITaxon:469598
NCBITaxon:662101
NCBITaxon:662104
GC_ID:11
PMID:10319482
E. coli
Escherichia/Shigella coli
ncbi_taxonomy
Bacillus coli
Bacterium coli
Bacterium coli commune
Enterococcus coli
Escherichia coli
E. coli
Escherichia/Shigella coli
Bacillus coli
Bacterium coli
Bacterium coli commune
Enterococcus coli
GC_ID:1
ncbi_taxonomy
Eumetazoa
GC_ID:1
arthropods
ncbi_taxonomy
arthropods
Arthropoda
arthropods
arthropods
GC_ID:1
insects
ncbi_taxonomy
Atelocerata
Tracheata
Uniramia
insects
Hexapoda
insects
Atelocerata
Tracheata
Uniramia
insects
GC_ID:1
flies
ncbi_taxonomy
flies
Diptera
flies
flies
GC_ID:1
ncbi_taxonomy
Brachycera
GC_ID:1
pomace flies
ncbi_taxonomy
Drosophilidae
pomace flies
NCBITaxon:7326
GC_ID:1
Drosophila
fruit flies
fruit fly
ncbi_taxonomy
Drosophila <flies,genus>
Drosophila
fruit flies
fruit fly
NCBITaxon:2267365
GC_ID:1
fruit fly
ncbi_taxonomy
Sophophora melanogaster
Drosophila melanogaster
fruit fly
Sophophora melanogaster
GC_ID:1
Pterygota
winged insects
ncbi_taxonomy
Pterygota <insects>
Pterygota
winged insects
GC_ID:1
chordates
ncbi_taxonomy
chordates
Chordata
chordates
chordates
GC_ID:1
Vertebrata
vertebrates
ncbi_taxonomy
vertebrates
Vertebrata <vertebrates>
Vertebrata
vertebrates
vertebrates
GC_ID:1
Gnathostomata
jawed vertebrates
ncbi_taxonomy
Gnathostomata <vertebrates>
Gnathostomata
jawed vertebrates
GC_ID:1
ncbi_taxonomy
Sarcopterygii
GC_ID:11
Escherichia coli K12
ncbi_taxonomy
Escherichia coli K-12
Escherichia coli K12
GC_ID:1
ncbi_taxonomy
Dicondylia
GC_ID:1
ncbi_taxonomy
Panarthropoda
GC_ID:1
Craniata
ncbi_taxonomy
Craniata <chordates>
Craniata
GC_ID:11
PMID:27620848
ncbi_taxonomy
Enterobacteriaceae and related endosymbionts
Enterobacteriaceae group
Enterobacteriales
enterobacteria
gamma-3 proteobacteria
Enterobacterales
Enterobacteriaceae and related endosymbionts
Enterobacteriaceae group
Enterobacteriales
enterobacteria
gamma-3 proteobacteria
GC_ID:1
eutherian mammals
placental mammals
placentals
ncbi_taxonomy
Placentalia
placentals
Eutheria
eutherian mammals
placental mammals
placentals
Placentalia
placentals
GC_ID:1
primate
ncbi_taxonomy
Primata
primates
Primates
primate
Primata
primates
GC_ID:1
ncbi_taxonomy
Catarrhini
GC_ID:1
great apes
ncbi_taxonomy
Pongidae
Hominidae
great apes
Pongidae
GC_ID:1
humans
ncbi_taxonomy
Homo
humans
human being
GC_ID:1
human
man
ncbi_taxonomy
Homo sapiens
human
man
regulator role
Fact sheet - Regulating the companies The role of the regulator. Ofwat is the economic regulator of the water and sewerage industry in England and Wales. http://www.ofwat.gov.uk/aptrix/ofwat/publish.nsf/Content/roleofregulator_factsheet170805
a regulatory role involved with making and/or enforcing relevant legislation and governmental orders
Person:Jennifer Fostel
regulator
OBI
regulator role
regulatory role
Regulatory agency, Ethics committee, Approval letter; example: Browse these EPA Regulatory Role subtopics http://www.epa.gov/ebtpages/enviregulatoryrole.html Feb 29, 2008
a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body.
GROUP: Role branch
OBI, CDISC
govt agents responsible for creating regulations; proxies for enforcing regulations. CDISC definition: regulatory authorities. Bodies having the power to regulate. NOTE: In the ICH GCP guideline the term includes the authorities that review submitted clinical data and those that conduct inspections. These bodies are sometimes referred to as competent
regulatory role
material supplier role
Jackson Labs is an organization which provide mice as experimental material
a role realized through the process of supplying materials such as animal subjects, reagents or other materials used in an investigation.
Supplier role is a special kind of service, e.g. biobank
PERSON:Jennifer Fostel
material provider role
supplier
material supplier role
classified data set
A data set that is produced as the output of a class prediction data transformation and consists of a data set with assigned class labels.
PERSON: James Malone
PERSON: Monnie McGee
data set with assigned class labels
classified data set
evaluant role
When a specimen of blood is assayed for glucose concentration, the blood has the evaluant role. When measuring the mass of a mouse, the evaluant is the mouse. When measuring the time of DNA replication, the evaluant is the DNA. When measuring the intensity of light on a surface, the evaluant is the light source.
a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role
Role call - 17nov-08: JF and MC think an evaluant role is always specified input of a process. Even in the case where we have an assay taking blood as evaluant and outputting blood, the blood is not the specified output at the end of the assay (the concentration of glucose in the blood is)
examples of features that could be described in an evaluant: quality.... e.g. "contains 10 pg/ml IL2", or "no glucose detected")
GROUP: Role Branch
OBI
Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term.
evaluant role
culture medium
A growth medium or culture medium is a substance in which microorganisms or cells can grow. Wikipedia, growth medium, Feb 29, 2008
a processed material that provides the needed nourishment for microorganisms or cells grown in vitro.
changed from a role to a processed material based on on Aug 22, 2011 dev call. Details see the tracker item: http://sourceforge.net/tracker/?func=detail&aid=3325270&group_id=177891&atid=886178
Modification made by JZ.
Person: Jennifer Fostel, Jie Zheng
OBI
culture medium
reagent role
Buffer, dye, a catalyst, a solvating agent.
A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer.
PERSON:Matthew Brush
reagent
PERSON:Matthew Brush
Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term.
May 28 2013. Updated definition taken from ReO based on discussions initiated in Philly 2011 workshop. Former defnition described a narrower view of reagents in chemistry that restricts bearers of the role to be chemical entities ("a role played by a molecular entity used to produce a chemical reaction to detect, measure, or produce other substances"). Updated definition allows for broader view of reagents in the domain of biomedical research to include larger materials that have parts that participate chemically in a molecular reaction or interaction.
(copied from ReO)
Reagents are distinguished from instruments or devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique. By contrast, instruments do not participate in a chemical reaction/interaction during the technique.
Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not. It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance will realize only one of these roles in the execution of a given assay or technique. For example, taq polymerase can bear a reagent role or an evaluant role. In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.
In regard to the statement that reagents are 'distinct' from the specified outputs of a technique, note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role. For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it. Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).
reagent role
study subject role
Human subjects in a clinical trial, rats in a toxicogenomics study, tissue cutlures subjected to drug tests, fish observed in an ecotoxicology study.
Parasite example: people are infected with a parasite which is then extracted; the particpant under investigation could be the parasite, the people, or a population of which the people are members, depending on the nature of the study.
Lake example: a lake could realize this role in an investigation that assays pollution levels in samples of water taken from the lake.
A role that is realized through the execution of a study design in which the bearer of the role participates and in which data about that bearer is collected.
A participant can realize both "specimen role" and "participant under investigation role" at the same time. However "participant under investigation role" is distinct from "specimen role", since a specimen could somehow be involved in an investigation without being the thing that is under investigation.
GROUP: Role Branch
OBI
Following OBI call November 2012,26th:
1. it was decided there was no need for moving the children class and making them siblings of study subject role.
2. it also settles the disambiguation about 'study subject'. This is about the individual participating in the investigation/study, Not the 'topic' (as in 'toxicity study') of the investigation/study
This note closes the issue and validates the class definition to be part of the OBI core
editor = PRS
participant under investigation role
specimen role
liver section; a portion of a culture of cells; a nemotode or other animal once no longer a subject (generally killed); portion of blood from a patient.
a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation
22Jun09. The definition includes whole organisms, and can include a human. The link between specimen role and study subject role has been removed. A specimen taken as part of a case study is not considered to be a population representative, while a specimen taken as representing a population, e.g. person taken from a cohort, blood specimen taken from an animal) would be considered a population representative and would also bear material sample role.
Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation.
blood taken from animal: animal continues in study, whereas blood has role specimen.
something taken from study subject, leaves the study and becomes the specimen.
parasite example
- when parasite in people we study people, people are subjects and parasites are specimen
- when parasite extracted, they become subject in the following study
specimen can later be subject.
GROUP: Role Branch
OBI
specimen role
population
PMID12564891. Environ Sci Technol. 2003 Jan 15;37(2):223-8. Effects of historic PCB exposures on the reproductive success of the Hudson River striped bass population.
a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area
1/28/2013, BP, on the call it was raised that we may want to switch to an external ontology for all populatin terms:
http://code.google.com/p/popcomm-ontology/
PERSON: Philippe Rocca-Serra
adapted from Oxford English Dictionnary
rem1: collection somehow always involve a selection process
population
investigation agent role
The person perform microarray experiments and submit microarray results (including raw data, processed data) with experiment description to ArrayExpress.
A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing.
Implementing a study means carrying out or performing the study and providing reagents or other materials used in the study and other tasks without which the study would not happen.
Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable representing investigations run by robot scientists such as ADAM (King et al, Science, 2009)
GROUP: Role Branch
investigator
OBI
Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term.
study person role
Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable investigations run by robot scientists such as ADAM (King et al, Science, 2009)
investigation agent role
protocol
PCR protocol, has objective specification, amplify DNA fragment of interest, and has action specification describes the amounts of experimental reagents used (e..g. buffers, dNTPS, enzyme), and the temperature and cycle time settings for running the PCR.
A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.
PlanAndPlannedProcess Branch
OBI branch derived + wikipedia (http://en.wikipedia.org/wiki/Protocol_%28natural_sciences%29)
study protocol
protocol
interpreting data
Concluding that a gene is upregulated in a tissue sample based on the band intensity in a western blot. Concluding that a patient has a infection based on measurement of an elevated body temperature and reported headache. Concluding that there were problems in an investigation because data from PCR and microarray are conflicting. Concluding that 'defects in gene XYZ cause cancer due to improper DNA repair' based on data from experiments in that study that gene XYZ is involved in DNA repair, and the conclusion of a previous study that cancer patients have an increased number of mutations in this gene.
A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion
PERSON: Bjoern Peters
PERSON: Jennifer Fostel
Bjoern Peters
drawing a conclusion based on data
planning
The process of a scientist thinking about and deciding what reagents to use as part of a protocol for an experiment. Note that the scientist could be human or a "robot scientist" executing software.
a process of creating or modifying a plan specification
7/18/2011 BP: planning used to itself be a planned process. Barry Smith pointed out that this would lead to an infinite regression, as there would have to be a plan to conduct a planning process, which in itself would be the result of planning etc. Therefore, the restrictions on 'planning' were loosened to allow for informal processes that result in an 'ad hoc plan '. This required changing from 'has_specified_output some plan specifiction' to 'has_participant some plan specification'.
Bjoern Peters
Bjoern Peters
Plans and Planned Processes Branch
planning
analyte measurement objective
The objective to measure the concentration of glucose in a blood sample
an assay objective to determine the presence or concentration of an analyte in the evaluant
PERSON: Bjoern Peters
PPPB branch
analyte measurement objective
assay objective
the objective to determine the weight of a mouse.
an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)
PPPB branch
PPPB branch
assay objective
example of usage: In lab test for blood glucose, the test is the assay, the blood bears evaluant_role and glucose bears the analyte role. The evaluant is considered an input to the assay and the information entity that records the measurement of glucose concentration the output
An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant.
Alan Ruttenberg
Bjoern Peters
Helen Parkinson
Philippe Rocca-Serra
Alan Ruttenberg
Bjoern Peters
Helen Parkinson
OBI Planned process branch
Philippe Rocca-Serra
analyte assay
regulatory agency
The US Environmental Protection Agency
A regulatory agency is a organization that has responsibility over or for the legislation (acts and regulations) for a given sector of the government.
GROUP: OBI Biomaterial Branch
WEB: en.wikipedia.org/wiki/Regulator
regulatory agency
measure function
A glucometer measures blood glucose concentration, the glucometer has a measure function.
Measure function is a function that is borne by a processed material and realized in a process in which information about some entity is expressed relative to some reference.
PERSON: Daniel Schober
PERSON: Helen Parkinson
PERSON: Melanie Courtot
PERSON:Frank Gibson
measure function
material transformation objective
The objective to create a mouse infected with LCM virus. The objective to create a defined solution of PBS.
an objective specifiction that creates an specific output object from input materials.
PERSON: Bjoern Peters
PERSON: Frank Gibson
PERSON: Jennifer Fostel
PERSON: Melanie Courtot
PERSON: Philippe Rocca-Serra
artifact creation objective
GROUP: OBI PlanAndPlannedProcess Branch
material transformation objective
study design execution
injecting a mouse with PBS solution, weighing it, and recording the weight according to a study design.
a planned process that carries out a study design
removed axiom has_part some (assay or 'data transformation') per discussion on protocol application mailing list to improve reasoner performance. The axiom is still desired.
branch derived
6/11/9: edited at workshop. Used to be: study design execution is a process with the objective to generate data according to a concretized study design. The execution of a study design is part of an investigation, and minimally consists of an assay or data transformation.
study design execution
manufacturer role
With respect to The Accuri C6 Flow Cytometer System, the organization Accuri bears the role manufacturer role. With respect to a transformed line of tissue culture cells derived by a specific lab, the lab whose personnel isolated the cll line bears the role manufacturer role. With respect to a specific antibody produced by an individual scientist, the scientist who purifies, characterizes and distributes the anitbody bears the role manufacturer role.
Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process.
GROUP: Role Branch
OBI
manufacturer role
material separation objective
The objective to obtain multiple aliquots of an enzyme preparation. The objective to obtain cells contained in a sample of blood.
is an objective to transform a material entity into spatially separated components.
PPPB branch
PPPB branch
material separation objective
clustered data set
A clustered data set is the output of a K means clustering data transformation
A data set that is produced as the output of a class discovery data transformation and consists of a data set with assigned discovered class labels.
PERSON: James Malone
PERSON: Monnie McGee
data set with assigned discovered class labels
AR thinks could be a data item instead
clustered data set
drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation
A planned process with the objective of collecting a specimen.
Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation.
Philly2013: A specimen collection can have as part a material entity acquisition, such as ordering from a bank. The distinction is that specimen collection necessarily involves the creation of a specimen role. However ordering cell lines cells from ATCC for use in an investigation is NOT a specimen collection, because the cell lines already have a specimen role.
Philly2013: The specimen_role for the specimen is created during the specimen collection process.
label changed to 'specimen collection process' on 10/27/2014, details see tracker:
http://sourceforge.net/p/obi/obi-terms/716/
Bjoern Peters
specimen collection
5/31/2012: This process is not necessarily an acquisition, as specimens may be collected from materials already in posession
6/9/09: used at workshop
specimen collection process
class prediction data transformation
A class prediction data transformation (sometimes called supervised classification) is a data transformation that has objective class prediction.
James Malone
supervised classification data transformation
PERSON: James Malone
class prediction data transformation
portioning objective
The objective to obtain multiple aliquots of an enzyme preparation.
A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material.
portioning objective
separation into different composition objective
The objective to obtain cells contained in a sample of blood.
A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities).
We should be using has the grain relations or concentrations to distinguish the portioning and other sub-objectives
separation into different composition objective
The objective to collect bits of excrement in the rainforest. The objective to obtain a blood sample from a patient.
A objective specification to obtain a material entity for potential use as an input during an investigation.
Bjoern Peters
Bjoern Peters
specimen collection objective
support vector machine
A support vector machine is a data transformation with a class prediction objective based on the construction of a separating hyperplane that maximizes the margin between two data sets of vectors in n-dimensional space.
James Malone
Ryan Brinkman
SVM
PERSON: Ryan Brinkman
support vector machine
decision tree induction objective
A decision tree induction objective is a data transformation objective in which a tree-like graph of edges and nodes is created and from which the selection of each branch requires that some type of logical decision is made.
James Malone
decision tree induction objective
decision tree building data transformation
A decision tree building data transformation is a data transformation that has objective decision tree induction.
James Malone
PERSON: James Malone
decision tree building data transformation
GenePattern software
a software that provides access to more than 100 tools for gene expression analysis, proteomics, SNP analysis and common data processing tasks.
James Malone
Person:Helen Parkinson
WEB: http://www.broadinstitute.org/cancer/software/genepattern/
GenePattern software
peak matching
Peak matching is a data transformation performed on a dataset of a graph of ordered data points (e.g. a spectrum) with the objective of pattern matching local maxima above a noise threshold
James Malone
Ryan Brinkman
PERSON: Ryan Brinkman
peak matching
k-nearest neighbors
A k-nearest neighbors is a data transformation which achieves a class discovery or partitioning objective, in which an input data object with vector y is assigned to a class label based upon the k closest training data set points to y; where k is the largest value that class label is assigned.
James Malone
k-NN
PERSON: James Malone
k-nearest neighbors
CART
A CART (classification and regression trees) is a data transformation method for producing a classification or regression model with a tree-based structure.
James Malone
classification and regression trees
BOOK: David J. Hand, Heikki Mannila and Padhraic Smyth (2001) Principles of Data Mining.
CART
independent variable specification
In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, disease status is the independent variable.
a directive information entity that is part of a study design. Independent variables are entities whose values are selected to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled
2/2/2009 Original definition - In the design of experiments, independent variables are those whose values are controlled or selected by the person experimenting (experimenter) to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled.
In the Philly 2013 workshop the label was chosen to distinguish it from "dependent variable" as used in statistical modelling. See: http://en.wikipedia.org/wiki/Statistical_modeling
PERSON: Alan Ruttenberg
PERSON: Bjoern Peters
PERSON: Chris Stoeckert
experimental factor
independent variable
Web: http://en.wikipedia.org/wiki/Dependent_and_independent_variables
2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.
study factor
study design independent variable
dependent variable specification
In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, the gene expression is the dependent variable.
dependent variable specification is part of a study design. The dependent variable is the event studied and expected to change when the independent variable varies.
2/2/2009 In the design of experiments, independent variables are those whose values are controlled or selected by the person experimenting (experimenter) to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled.
In the Philly 2013 workshop the label was chosen to distinguish it from "dependent variable" as used in statistical modelling. See: http://en.wikipedia.org/wiki/Statistical_modeling
PERSON: Alan Ruttenberg
PERSON: Bjoern Peters
PERSON: Chris Stoeckert
dependent variable
WEB: http://en.wikipedia.org/wiki/Dependent_and_independent_variables
2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.
study design dependent variable
controlled variable specification
In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, age is a controlled variable.
Controlled variable specification is a part of a study design. They are the entities that could vary, but are kept constant to prevent their influence on the effect of the independent variable on the dependent.
2/2/2009 Original definition: Controlled variables are also important to identify in experiments. They are the variables that are kept constant to prevent their influence on the effect of the independent variable on the dependent. Every experiment has a controlling variable, and it is necessary to not change it, or the results of the experiment won't be valid
In the Philly 2013 workshop the label was chosen to distinguish it from "controlled variable" as used in statistical modelling
PERSON: Alan Ruttenberg
PERSON: Bjoern Peters
PERSON: Chris Stoeckert
controlled variable
WEB: http://en.wikipedia.org/wiki/Control_variable
2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI.
study design controlled variable
statistical model validation
Using the expression levels of 20 proteins to predict whether a cancer patient will respond to a drug. A practical goal would be to determine which subset of the 20 features should be used to produce the best predictive model. - wikipedia
A data transformation which assesses how the results of a statistical analysis will generalize to an independent data set.
Helen Parkinson
http://en.wikipedia.org/wiki/Cross-validation_%28statistics%29
statistical model validation
material maintenance objective
An objective specification maintains some or all of the qualities of a material over time.
PERSON: Bjoern Peters
PERSON: Bjoern Peters
material maintenance objective
informed consent process
A planned process in which a person or their legal representative is informed about key facts about potential risks and benefits of a process and makes a documented decision as to whether the person in question will participate.
09/28/2009 Alan Ruttenberg: This is made a subclass of the higher level processual entity in BFO because I don't want to take a stand on whether it is a process aggregate. Analogous to the situation with Material entity.
Person:Alan Ruttenberg
http://clinicaltrials.gov/ct2/info/glossary#informed
2009/09/28 Alan Ruttenberg. Fucoidan-use-case
informed consent process
measurement device
A ruler, a microarray scanner, a Geiger counter.
A device in which a measure function inheres.
GROUP:OBI Philly workshop
OBI
measurement device
manufacturer
A person or organization that has a manufacturer role
manufacturer
material maintenance
a process with that achieves the objective to maintain some or all of the characteristics of an input material over time
material maintenance
service provider role
Jackson Lab provides experimental animals, EBI provides training on databases, a core facility provides access to a DNA sequencer.
is a role which inheres in a person or organization and is realized in in a planned process which provides access to training, materials or execution of protocols for an organization or person
PERSON:Helen Parkinson
service provider role
processed specimen
A tissue sample that has been sliced and stained for a histology study.
A blood specimen that has been centrifuged to obtain the white blood cells.
A specimen that has been intentionally physically modified.
Bjoern Peters
Bjoern Peters
A tissue sample that has been sliced and stained for a histology study.
processed specimen
categorical label
The labels 'positive' vs. 'negative', or 'left handed', 'right handed', 'ambidexterous', or 'strongly binding', 'weakly binding' , 'not binding', or '+++', '++', '+', '-' etc. form scales of categorical labels.
A label that is part of a categorical datum and that indicates the value of the data item on the categorical scale.
Bjoern Peters
Bjoern Peters
categorical label
device
A voltmeter is a measurement device which is intended to perform some measure function.
An autoclave is a device that sterlizes instruments or contaminated waste by applying high temperature and pressure.
A material entity that is designed to perform a function in a scientific investigation, but is not a reagent.
2012-12-17 JAO: In common lab usage, there is a distinction made between devices and reagents that is difficult to model. Therefore we have chosen to specifically exclude reagents from the definition of "device", and are enumerating the types of roles that a reagent can perform.
2013-6-5 MHB: The following clarifications are outcomes of the May 2013 Philly Workshop. Reagents are distinguished from devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in some chemical interaction or reaction during the realization of their experimental role. By contrast, devices do not participate in such chemical reactions/interactions. Note that there are cases where devices use reagent components during their operation, where the reagent-device distinction is less clear. For example:
(1) An HPLC machine is considered a device, but has a column that holds a stationary phase resin as an operational component. This resin qualifies as a device if it participates purely in size exclusion, but bears a reagent role that is realized in the running of a column if it interacts electrostatically or chemically with the evaluant. The container the resin is in (“the column”) considered alone is a device. So the entire column as well as the entire HPLC machine are devices that have a reagent as an operating part.
(2) A pH meter is a device, but its electrode component bears a reagent role in virtue of its interacting directly with the evaluant in execution of an assay.
(3) A gel running box is a device that has a metallic lead as a component that participates in a chemical reaction with the running buffer when a charge is passed through it. This metallic lead is considered to have a reagent role as a component of this device realized in the running of a gel.
In the examples above, a reagent is an operational component of a device, but the device itself does not realize a reagent role (as bearing a reagent role is not transitive across the part_of relation). In this way, the asserted disjointness between a reagent and device holds, as both roles are never realized in the same bearer during execution of an assay.
PERSON: Helen Parkinson
instrument
OBI development call 2012-12-17.
device
questionnaire
A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study.
JT: It plays a role in collecting data that could be fleshed out more; but I'm thinking it is, in itself, an edited document.
JZ: based on textual definition of edited document, it can be defined as N&S. I prefer to leave questionnaire as a document now. We can add more restrictions in the future and use that to determine it is an edited document or not.
Need to clarify if this is a document or a directive information entity (or what their connection is))
PERSON: Jessica Turner
Merriam-Webster
questionnaire
rats should be aged between 6 and 8 weeks and weight between 180-250grams
A directive information entity which defines and states a principle of standard by which selection process may take place.
Person: Philippe Rocca-Serra
selection rule
OBI discussion summarized under the following tracker item : http://sourceforge.net/p/obi/obi-terms/678/
selection criterion
secondary cultured cell
A cultured cell that has been passaged or derives from a cell that has been passaged in culture.
The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture.
Person: Matthew Brush
PERSON: Matthew Brush
A secondary cultured cell has been passaged in culture or is a descendant of such a cell that is derived through propagation in culture.
secondary cultured cell
A biological or chemical entity that bears a reagent role in virtue of it being intended for application in a scientific technique to participate in (or have molecular parts that participate in) a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material specified output.
2013-6-5 MHB: Clarifications regarding the distinction between reagetns and devices were made at the May 2013 Philly Workshop. Reagents are distinguished from devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in some chemical interaction or reaction during the realization of their experimental role. By contrast, devices do not participate in such chemical reactions/interactions. Note that there are cases where devices use reagent components during their operation, where the reagent-device distinction is less clear. For examples, see editor note on OBI:device.
PERSON:Matthew Brush
PERSON:Matthew Brush
(copied from ReO)
Reagents are distinguished from devices/instruments that also serve as facilitators in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique. By contrast, devices do not participate in a chemical reaction/interaction during the technique.
Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not. It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance can only realize one of these roles in the execution of a given assay. For example, taq polymerase can bear a reagent role or an evaluant role. In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.
In regard to the statement that reagents are 'distinct' from the specified outputs of a technique: note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role. For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it. Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).
reagent
that fucoidan has a small statistically significant effect on AT3 level but no useful clinical effect as in-vivo anticoagulant, a paraphrase of part of the last paragraph of the discussion section of the paper 'Pilot clinical study to evaluate the anticoagulant activity of fucoidan', by Lowenthal et. al.PMID:19696660
An information content entity that expresses an assertion that is intended to be tested.
In the Philly 2013 workshop, we recognized the limitations of "hypothesis textual entity", and we introduced this as more general. The need for the 'textual entity' term going forward is up for future debate.
Group:2013 Philly Workshop group
hypothesis
Group:2013 Philly Workshop group
testable hypothesis
cell freezing medium
A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles.
PERSON: Matthew Brush
cell freezing medium
PMID: 24023800. In this study, a set of eleven genes (VATP16, 60 S, UQCC, SMD3, EF1α, UBQ, SAND, GAPDH, ACT, PsaB, PTB2) was evaluated to identify reference genes during the first hours of interaction (6, 12, 18 and 24 hpi) between two V. vinifera genotypes and P. viticola. Two analyses were used for the selection of reference genes: direct comparison of susceptible, Trincadeira, and resistant, Regent, V. vinifera cultivars at 0 h, 6, 12, 18 and 24 hours post inoculation with P. viticola (genotype effect); and comparison of each genotype with mock inoculated samples during inoculation time-course (biotic stress effect). Three statistical methods were used, GeNorm, NormFinder, and BestKeeper, allowing to identify UBQ, EF1α and GAPDH as the most stable genes for the genotype effect.
A planned process which results in the creation of group of entity from a larger group by the application of predefined criteria.
this term refers to a planned process and therefore is distinct from the notion of 'natural selection', a process covering the operation of natural causes by which those individuals of a species that are best adapted to the environment tend to be preserved and to transmit their characters, while those less adapted die out, so that in the course of generations the degree of adaptation to the environment tends progressively to increase. (as defined by Oxford English Dictionary)
Person: Philippe Rocca-Serra
selection process
OBI
selection
A value specification that is specifies one category out of a fixed number of nominal categories
PERSON:Bjoern Peters
categorical value specification
The value of 'positive' in a classification scheme of "positive or negative"; the value of '20g' on the quantitative scale of mass.
An information content entity that specifies a value within a classification scheme or on a quantitative scale.
This term is currently a descendant of 'information content entity', which requires that it 'is about' something. A value specification of '20g' for a measurement data item of the mass of a particular mouse 'is about' the mass of that mouse. However there are cases where a value specification is not clearly about any particular. In the future we may change 'value specification' to remove the 'is about' requirement.
PERSON:Bjoern Peters
value specification
An intracellular material detection by flow cytometry assay measuring peforin inside a culture of T cells.
An assay that measures properties of cells.
IEDB
IEDB
cytometry assay
collection of specimens
Blood cells collected from multiple donors over the course of a study.
A material entity that has two or more specimens as its parts.
Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/
Person: Chris Stoeckert, Jie Zheng
OBIB, OBI
Biobank
collection of specimens
G4: Undifferentiated
G1:Well differentiated
A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the American Joint Committee on Cancer (AJCC) 7th Edition grading system.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
histologic grade according to AJCC 7th edition
A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the Fuhrman Nuclear Grading System.
Chris Stoeckert, Helena Ellis
Histologic Grade (Fuhrman Nuclear Grading System)
NCI BBRB, OBI
NCI BBRB
histologic grade according to the Fuhrman Nuclear Grading System
A categorical value specification that is a histologic grade assigned to a ovarian tumor.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
histologic grade for ovarian tumor
A histologic grade for ovarian tumor that is from a two-tier histological classification of tumors.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
histologic grade for ovarian tumor according to a two-tier grading system
A histologic grade for ovarian tumor that is from a histological classification by the World Health Organization (WHO).
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
histologic grade for ovarian tumor according to the World Health Organization
A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
Chris Stoeckert, Helena Ellis
pT: Pathologic spread colorectal primary tumor (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic primary tumor stage for colon and rectum according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
Chris Stoeckert, Helena Ellis
pT: Pathologic spread lung primary tumor (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic primary tumor stage for lung according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
Chris Stoeckert, Helena Ellis
pT: Pathologic spread kidney primary tumor (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic primary tumor stage for kidney according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
Chris Stoeckert, Helena Ellis
pT: Pathologic spread ovarian primary tumor (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic primary tumor stage for ovary according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
Chris Stoeckert, Helena Ellis
pN: Pathologic spread colon lymph nodes (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic lymph node stage for colon and rectum according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
Chris Stoeckert, Helena Ellis
pN: Pathologic spread colon lymph nodes (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic lymph node stage for lung according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
Chris Stoeckert, Helena Ellis
pN: Pathologic spread kidney lymph nodes (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic lymph node stage for kidney according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
Chris Stoeckert, Helena Ellis
pN: Pathologic spread ovarian lymph nodes (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic lymph node stage for ovary according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of colon cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
Chris Stoeckert, Helena Ellis
M: colon distant metastases (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic distant metastases stage for colon according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
Chris Stoeckert, Helena Ellis
M: lung distant metastases (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic distant metastases stage for lung according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
Chris Stoeckert, Helena Ellis
M: kidney distant Metastases (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic distant metastases stage for kidney according to AJCC 7th edition
A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
Chris Stoeckert, Helena Ellis
M: ovarian distant metastases (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
pathologic distant metastases stage for ovary according to AJCC 7th edition
A categorical value specification that is an assessment of the stage of a cancer according to the American Joint Committee on Cancer (AJCC) v7 staging systems.
Chris Stoeckert, Helena Ellis
Clinical tumor stage group (AJCC 7th Edition)
NCI BBRB, OBI
NCI BBRB
clinical tumor stage group according to AJCC 7th edition
A categorical value specification that is an assessment of the stage of a gynecologic cancer according to the International Federation of Gynecology and Obstetrics (FIGO) staging systems.
Chris Stoeckert, Helena Ellis
Clinical FIGO stage
NCI BBRB, OBI
NCI BBRB
International Federation of Gynecology and Obstetrics cervical cancer stage value specification
A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the FIGO classification system.
Chris Stoeckert, Helena Ellis
Pathologic Tumor Stage Grouping for ovarian cancer (FIGO)
NCI BBRB, OBI
NCI BBRB
International Federation of Gynecology and Obstetrics ovarian cancer stage value specification
A categorical value specification that is an assessment of a participant's performance status (general well-being and activities of daily life).
Chris Stoeckert, Helena Ellis
Performance Status Scale
https://en.wikipedia.org/wiki/Performance_status
NCI BBRB
performance status value specification
A performance status value specification designed by the Eastern Cooperative Oncology Group to assess disease progression and its affect on the daily living abilities of the patient.
Chris Stoeckert, Helena Ellis
ECOG score
NCI BBRB, OBI
NCI BBRB
Eastern Cooperative Oncology Group score value specification
A performance status value specification designed for classifying patients 16 years of age or older by their functional impairment.
Chris Stoeckert, Helena Ellis
Karnofsky Score
NCI BBRB, OBI
NCI BBRB
Karnofsky score vaue specification
Epstein Barr virus transformed B cell
PMID: 8777380. Expression of thyroid peroxidase in EBV-transformed B cell lines using adenovirus.Thyroid. 1996 Feb;6(1):23-8.
A material entity which results from viral transformation process using EBV as transformation agent when applied to B-cell entity
PERSON: Susanna Sansone
GROUP: OBI Biomaterial Branch
Epstein Barr virus transformed B cell
specimen
Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen.
A material entity that has the specimen role.
Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation.
PERSON: James Malone
PERSON: Philippe Rocca-Serra
GROUP: OBI Biomaterial Branch
specimen
cultured cell population
A cultured cell population applied in an experiment: "293 cells expressing TrkA were serum-starved for 18 hours and then neurotrophins were added for 10 min before cell harvest." (Lee, Ramee, et al. "Regulation of cell survival by secreted proneurotrophins." Science 294.5548 (2001): 1945-1948).
A cultured cell population maintained in vitro: "Rat cortical neurons from 15 day embryos are grown in dissociated cell culture and maintained in vitro for 8–12 weeks" (Dichter, Marc A. "Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation." Brain Research 149.2 (1978): 279-293).
A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history.
2013-6-5 MHB: This OBI class was formerly called 'cell culture', but label changed and definition updated following CLO alignment efforts in spring 2013, during which the intent of this class was clarified to refer to portions of a culture or line rather than a complete cell culture or line.
PERSON:Matthew Brush
cell culture sample
PERSON:Matthew Brush
The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally.
cultured cell population
leave one out cross validation method
The authors conducted leave-one-out cross validation to estimate the strength and accuracy of the differentially expressed filtered genes. http://bioinformatics.oxfordjournals.org/cgi/content/abstract/19/3/368
is a data transformation : leave-one-out cross-validation (LOOCV) involves using a single observation from the original sample as the validation data, and the remaining observations as the training data. This is repeated such that each observation in the sample is used once as the validation data
2009-11-10. Tracker: https://sourceforge.net/tracker/?func=detail&aid=2893049&group_id=177891&atid=886178
Person:Helen Parkinson
leave one out cross validation method
k-means clustering
A k-means clustering is a data transformation which achieves a class discovery or partitioning objective, which takes as input a collection of objects (represented as points in multidimensional space) and which partitions them into a specified number k of clusters. The algorithm attempts to find the centers of natural clusters in the data. The most common form of the algorithm starts by partitioning the input points into k initial sets, either at random or using some heuristic data. It then calculates the mean point, or centroid, of each set. It constructs a new partition by associating each point with the closest centroid. Then the centroids are recalculated for the new clusters, and the algorithm repeated by alternate applications of these two steps until convergence, which is obtained when the points no longer switch clusters (or alternatively centroids are no longer changed).
Elisabetta Manduchi
James Malone
Philippe Rocca-Serra
WEB: http://en.wikipedia.org/wiki/K-means
k-means clustering
hierarchical clustering
A hierarchical clustering is a data transformation which achieves a class discovery objective, which takes as input data item and builds a hierarchy of clusters. The traditional representation of this hierarchy is a tree (visualized by a dendrogram), with the individual input objects at one end (leaves) and a single cluster containing every object at the other (root).
James Malone
WEB: http://en.wikipedia.org/wiki/Data_clustering#Hierarchical_clustering
hierarchical clustering
dimensionality reduction
A dimensionality reduction is data partitioning which transforms each input m-dimensional vector (x_1, x_2, ..., x_m) into an output n-dimensional vector (y_1, y_2, ..., y_n), where n is smaller than m.
Elisabetta Manduchi
James Malone
Melanie Courtot
Philippe Rocca-Serra
data projection
PERSON: Elisabetta Manduchi
PERSON: James Malone
PERSON: Melanie Courtot
dimensionality reduction
principal components analysis dimensionality reduction
A principal components analysis dimensionality reduction is a dimensionality reduction achieved by applying principal components analysis and by keeping low-order principal components and excluding higher-order ones.
Elisabetta Manduchi
James Malone
Melanie Courtot
Philippe Rocca-Serra
pca data reduction
PERSON: Elisabetta Manduchi
PERSON: James Malone
PERSON: Melanie Courtot
principal components analysis dimensionality reduction
data visualization
Generation of a heatmap from a microarray dataset
An planned process that creates images, diagrams or animations from the input data.
Elisabetta Manduchi
James Malone
Melanie Courtot
Tina Boussard
data encoding as image
visualization
PERSON: Elisabetta Manduchi
PERSON: James Malone
PERSON: Melanie Courtot
PERSON: Tina Boussard
Possible future hierarchy might include this:
information_encoding
>data_encoding
>>image_encoding
data visualization
data transformation objective
normalize objective
An objective specification to transformation input data into output data
Modified definition in 2013 Philly OBI workshop
James Malone
PERSON: James Malone
data transformation objective
partitioning data transformation
A partitioning data transformation is a data transformation that has objective partitioning.
James Malone
PERSON: James Malone
partitioning data transformation
partitioning objective
A k-means clustering which has partitioning objective is a data transformation in which the input data is partitioned into k output sets.
A partitioning objective is a data transformation objective where the aim is to generate a collection of disjoint non-empty subsets whose union equals a non-empty input set.
Elisabetta Manduchi
James Malone
PERSON: Elisabetta Manduchi
partitioning objective
class discovery data transformation
A class discovery data transformation (sometimes called unsupervised classification) is a data transformation that has objective class discovery.
James Malone
clustering data transformation
unsupervised classification data transformation
PERSON: James Malone
class discovery data transformation
class discovery objective
A class discovery objective (sometimes called unsupervised classification) is a data transformation objective where the aim is to organize input data (typically vectors of attributes) into classes, where the number of classes and their specifications are not known a priori. Depending on usage, the class assignment can be definite or probabilistic.
James Malone
clustering objective
discriminant analysis objective
unsupervised classification objective
PERSON: Elisabetta Manduchi
PERSON: James Malone
class discovery objective
class prediction objective
A class prediction objective (sometimes called supervised classification) is a data transformation objective where the aim is to create a predictor from training data through a machine learning technique. The training data consist of pairs of objects (typically vectors of attributes) and
class labels for these objects. The resulting predictor can be used to attach class labels to any valid novel input object. Depending on usage, the prediction can be definite or probabilistic. A classification is learned from the training data and can then be tested on test data.
James Malone
classification objective
supervised classification objective
PERSON: Elisabetta Manduchi
PERSON: James Malone
class prediction objective
cross validation objective
A cross validation objective is a data transformation objective in which the aim is to partition a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subset(s) are retained for subsequent use in confirming and validating the initial analysis.
James Malone
rotation estimation objective
WEB: http://en.wikipedia.org/wiki/Cross_validation
cross validation objective
clustered data visualization
A data visualization which has input of a clustered data set and produces an output of a report graph which is capable of rendering data of this type.
James Malone
clustered data visualization
study design
a matched pairs study design describes criteria by which subjects are identified as pairs which then undergo the same protocols, and the data generated is analyzed by comparing the differences between the paired subjects, which constitute the results of the executed study design.
A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution.
Editor note: there is at least an implicit restriction on the kind of data transformations that can be done based on the measured data available.
PERSON: Chris Stoeckert
experimental design
rediscussed at length (MC/JF/BP). 12/9/08). The definition was clarified to differentiate it from protocol.
study design
eligibility criterion
PMID: 17579629 -Eligibility criteria included: untreated ED-SCLC; age >/=70 and performance status 0-2, or age <70 and PS 3.
an eligibility criterion (rule) is_a selection criterion which
defines and states the requirements (positive or negative) for an entity to be considered as suitable for a given task or participation in a process.
Person: Philippe Rocca-Serra
eligibility rule
Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group
eligibility criterion
human subject enrollment
enlisting familiy members of HIV patients into a study
A planned process with the objective to obtain a population of human subjects to participate in an investigation by determining eligibility of subjects and obtaining informed consent.
As with group assignment, should the specified output here be an organism which bears a role
Bjoern Peters
IEDB
criteria come from plan / clinical trial branch
human subject enrollment
acquisition
Downloading a 3D structure from the PDB. Purchasing antibodies from sigma.
the planned process of gaining possession of a continuant
5/31/2012 - OBI workshop: This process is not implying ownership of the material / information.
Following OBI call November 2012,5th:
addition of a restriction to acquisition class to capture the need of having selection criteria
Relates to the creation of a class 'selection rule'
Bjoern Peters
IEDB
This needs to be fleshed out and logical definitions added that will allow to place the children terms automatically under acquisition
acquisition
material acquisition
Acquiring 50 C57BL/6 mice bred in the animal facility of the institute as a service to investigators. Purchasing 1 mg of peptides synthesized by Mimotopes at 80% purity. Getting a gift of purified CD4+ specific antibodies presented by Stephen Schoenberger at LIAI.
An acquisition in which possession of a material entity is gained.
The assumption is that the object already exists in its current state, e.g, an available mouse strain purchased from the Jackson Lab, this is the differentia from specimen creation
This excludes processes that create or change materials, such as material transformations.
Bjoern Peters, Alan Ruttenberg, Helen Parkinson
material procurement
IEDB
material acquisition
information acquisition
Gathering all influenza HA sequences from GenBank, Retrieveing HLA allele frequencies in the North American populations from dbMHC
An acquisition in which possession of information is gained.
This excludes processes that create or change information, such as assays and data transformations.
Bjoern Peters
data collection
OBI branch derived
information acquisition
material component separation
Using a cell sorter to separate a mixture of T cells into two fractions; one with surface receptor CD8 and the other lacking the receptor, or purification
a material processing in which components of an input material become segregated in space
Bjoern Peters
IEDB
material component separation
maintaining cell culture
When harvesting blood from a human, isolating T cells, and then limited dilution cloning of the cells, the maintaining_cell_culture step comprises all steps after the initial dilution and plating of the cells into culture, e.g. placing the culture into an incubator, changing or adding media, and splitting a cell culture
a protocol application in which cells are kept alive in a defined environment outside of an organism. part of cell_culturing
PlanAndPlannedProcess Branch
OBI branch derived
maintaining cell culture
'establishing cell culture'
a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line).
PERSON:Matthew Brush
PERSON:Matthew Brush
A 'cell culture' as used here referes to a new lineage of cells in culture deriving from a single biological source.. New cultures are established through the initial isolation and culturing of cells from an organismal source, or through changes in an existing cell culture or line that result in a new culture with unique characteristics. This can occur through the passaging/selection of a primary culture into a secondary culture or line, or experimental modifications of an existing cell culture or line such as an immortalization process or other stable genetic modification. This class covers establishment of cultures of either multicellular organism cells or unicellular organisms.
establishing cell culture
cell culture splitting
The act of taking a cell culture of high density, counting the cells, removing part of the cells, and re-seeding a select number of the cells into new flasks with fresh tissue culture media.
The act of taking part of a homogeneous cell culture and creating one or more additional separate cultures of similar qualities. input: cell_culture, output cell_culture min cardinality 2. part of cell culturing
PlanAndPlannedProcess Branch
cell culture passaging
OBI branch derived
An active cell culture is typically split when it has grown to confluence in its culture dish. Cell culture splitting of a cell culture sample results in an increase in its passage number, which measures how long a sample has been propagated in vitro, and therefore how many selective or genetic changes it is likely to have undergone.
cell culture splitting
CHEBI:33699
A unit which is a standard measure of the amount of a 2-dimensional flat surface.
http://purl.obolibrary.org/obo/uo.owl
george gkoutos
unit.ontology
area unit
2019-03-05T17:25:21Z
Western Australia Ecoregion
WWF:AA1310
https://www.worldwildlife.org/ecoregions/aa1310
Western Australian Mulga Shrublands Ecoregion
2019-03-05T17:51:32Z
https://www.worldwildlife.org/biomes/deserts-and-xeric-shrublands
Australasia Ecoregion
2019-03-05T17:52:41Z
Southern central Australia Ecoregion
WWF:AA1309
https://www.worldwildlife.org/ecoregions/aa1309
Tirari-Sturt Stony Desert Ecoregion
2019-03-05T17:54:35Z
Eastern central Australia Ecoregion
WWF:AA1308
https://www.worldwildlife.org/ecoregions/aa1308
Simpson Desert Region
2019-03-05T17:56:13Z
Western Australia Ecoregion
WWF:AA1307
https://www.worldwildlife.org/ecoregions/aa1307
Pilbara Shrublands Ecoregion
2019-03-05T18:10:52Z
Western coast of Australia Ecoregion
WWF:AA1301
https://www.worldwildlife.org/ecoregions/aa1301
Carnarvon Xeric Shrublands Ecoregion
2019-03-05T18:12:28Z
Central Australia Ecoregion
WWF:AA1302
https://www.worldwildlife.org/ecoregions/aa1302
Central Ranges Xeric Shrub Ecoregion
2019-03-05T18:15:11Z
Western central Australia
WWF:AA1303
https://www.worldwildlife.org/ecoregions/aa1303
Gibson Desert Ecoregion
2019-03-05T18:17:15Z
Northwestern Australia
WWF:AA1304
https://www.worldwildlife.org/ecoregions/aa1304
The Great Sandy-Tanami Desert Ecoregion
2019-03-05T18:24:06Z
Southern Australia Ecoregion
WWF:AA1305
https://www.worldwildlife.org/ecoregions/aa1305
Great Victoria Desert Ecoregion
2019-03-05T18:26:16Z
Southern Australia Ecoregion
WWF:AA1306
https://www.worldwildlife.org/ecoregions/aa1306
Nullarbor Plains Xeric Shrubland Ecoregion
2019-03-06T22:01:41Z
https://www.worldwildlife.org/biomes/deserts-and-xeric-shrublands
Afrotropical Ecoregion
2019-03-06T22:02:37Z
Southern Africa: Southern Namibia into South Africa
WWF:AT1322
https://www.worldwildlife.org/ecoregions/at1322
Succulent Karoo Ecoregion
2019-03-06T22:07:38Z
WWF:AT1321
https://www.worldwildlife.org/ecoregions/at1321
Arabian Peninsula: Yemen and Saudi Arabia
Yemen and Saudi Arabia Ecoregion
2019-03-06T22:11:38Z
WWF:AT1320
https://www.worldwildlife.org/ecoregions/at1320
Arabian Peninsula: Yemen, Saudi Arabia, and Oman
Yemen, Saudi Arabia, and Oman Ecoregion
2019-03-06T22:13:00Z
WWF:AT1319
https://www.worldwildlife.org/ecoregions/at1319
Somali montane xeric woodlands ecoregion
Somali Montane Xeric Woodland Ecoregion
2019-03-06T22:15:07Z
Islands east of the Horn of Africa and south of Yemen Ecoregion
WWF:AT1318
https://www.worldwildlife.org/ecoregions/at1318
Socotran Archipelago Ecoregion
2019-03-06T22:18:55Z
WWF:AT1317
https://www.worldwildlife.org/ecoregions/at1317
Red Sea Coastal Desert Ecoregion
2019-03-06T22:20:56Z
WWF:AT1316
https://www.worldwildlife.org/ecoregions/at1316
Namibian Savanna Woodland Ecoregion
2019-03-06T22:24:28Z
Africa: Namibia Ecoregion
WWF:AT1315
https://www.worldwildlife.org/ecoregions/at1315
Namib Desert Ecoregion
2019-03-06T22:26:15Z
WWF:AT1314
https://www.worldwildlife.org/ecoregions/at1314
Nama Karoo Ecoregion
2019-03-06T22:28:43Z
WWF:AT1313
https://www.worldwildlife.org/ecoregions/at1313
Masai Xeric Grasslands and Shrublands Ecoregion
2019-03-06T22:30:23Z
WWF:AT1312
https://www.worldwildlife.org/ecoregions/at1312
Madagascar Succulent Woodlands Ecoregion
2019-03-06T22:31:29Z
WWF:AT1311
https://www.worldwildlife.org/ecoregions/at1311
Madagascar spiny desert ecoregion
Madagascar Spiny Thickets Ecoregion
2019-03-06T22:39:32Z
WWF:AT1310
https://www.worldwildlife.org/ecoregions/at1310
Africa: Coastal Namibia and Angola Ecoregion
Kaokoveld Desert Ecoregion
2019-03-06T22:42:47Z
WWF:AT1309
https://www.worldwildlife.org/ecoregions/at1309
Kalahari Xeric Savanna Ecoregion
2019-03-06T22:44:54Z
WWF:AT1308
https://www.worldwildlife.org/ecoregions/at1308
Southern Africa: Islands about half-way between southern Madagascar and southern Mozambique Ecoregion
Ile Europa and Bassas da India Ecoregion
2019-03-06T22:46:58Z
Eastern Africa: Somalia
WWF:AT1307
https://www.worldwildlife.org/ecoregions/at1307
Hobyo Grassland and Shrubland Ecoregion
2019-03-06T22:54:57Z
WWF:AT1306
https://www.worldwildlife.org/ecoregions/at1306
Arabian Peninsula: Oman and United Arab Emirates Ecoregion
Oman and United Arab Emirates Ecoregion
2019-03-07T00:08:06Z
WWF:AT1305
https://www.worldwildlife.org/ecoregions/at1305
Ethiopian Xeric Grasslands and Shrublands Ecoregion
2019-03-07T00:11:29Z
WWF:AT1304
https://www.worldwildlife.org/ecoregions/at1304
Eritrean Coastal Desert Ecoregion
2019-03-07T00:13:33Z
WWF:AT1303
https://www.worldwildlife.org/ecoregions/at1303
North central Africa: Eastern Chad and small area of western Sudan
East Saharan Montane Xeric Woodland Ecoregion
2019-03-07T00:16:12Z
WWF:AT1302
https://www.worldwildlife.org/ecoregions/at1302
Western Asia: Oman, Yemen, and Saudi Arabia Ecoregion
Oman, Yemen, and Saudi Arabia Ecoregion
2019-03-07T00:18:09Z
WWF:AT1301
https://www.worldwildlife.org/ecoregions/at1301
Aldabra Island Xeric Scrub Ecoregion
2019-04-26T23:38:50Z
Indo-Malay Ecoregion
2019-04-26T23:40:13Z
WWF:IM1304
Southern Asia: Western India into Pakistan
Thar Desert
2019-04-27T00:12:51Z
WWF:IM1303
Southern Asia: Eastern India and western Pakistan
Northwestern Thorn Scrub Forests
A polar front between the deep, cold Arctic air and the shallower, warmer polar air of northern latitudes on Earth.
2019-08-20T13:47:18Z
envoAtmo
envoPolar
Arctic front
A polar front between the deep, cold Arctic air and the shallower, warmer polar air of northern latitudes on Earth.
A polar front between the deep, cold Antarctic air and the shallower, warmer polar air of southern latitudes on Earth.
2019-08-20T13:48:44Z
envoAtmo
envoPolar
Antarctic front
A polar front between the deep, cold Antarctic air and the shallower, warmer polar air of southern latitudes on Earth.
angular degree
angular degree
°
radian
A unit of measurement of planar angles where a full circle is 2π. Specifically the angle is the length of the arc subtended by the angle divided by the circumference of the circle.
Josh Hanna
William R. Hogan
Technically in the S.I. system it is a derived unit m•m^-1.
rad
radian
square mile
An area unit which is equal to the area enclosed by a square in a flat plane which is one mile on every side.
square mile
PERSON:Alan Ruttenberg
Transformation-ML
Transformation-ML file describing parameter transformations used in a GvHD experiment.
Transformation-ML is a format standard of a digital entity that is conformant with the Transformation-ML standard.(http://wiki.ficcs.org/ficcs/Transformation-ML?action=AttachFile&do=get&target=Transformation-ML_v1.0.26.pdf)
person:Jennifer Fostel
web-page:http://wiki.ficcs.org/ficcs/Transformation-ML?action=AttachFile&do=get&target=Transformation-ML_v1.0.26.pdf
Transformation-ML
ACS
d06.acs, ACS1.0 data file of well D06 of plate 2 of part 1 of a GvHD experiment.
ACS is a format standard of a digital entity that is conformant with the Analytical Cytometry Standard. (http://www.isac-net.org/content/view/607/150/)
person:Jennifer Fostel
web-page:http://www.isac-net.org/content/view/607/150/
ACS
XML
RDF/XML file, OWL file, Compensation-ML file, WSDL document, SVG document
XML is a format standard of a digital entity that is conformant with the W3C Extensible Markup Language Recommendation.(http://www.w3.org/XML/)
person:Jennifer Fostel
web-page:http://www.w3.org/XML/
XML
RDF
A FOAF file, a SKOS file, an OWL file.
RDF is a format standard of a digital entity that is conformant with the W3C Resource Description Framework RDF/XML Syntax specification.(http://www.w3.org/RDF/)
person:Jennifer Fostel
web-page:http://www.w3.org/RDF/
RDF
zip
MagicDraw MDZIP archive, Java JAR file.
zip is a format standard of a digital entity that is conformant with the PKWARE .ZIP file format specification (http://www.pkware.com/index.php?option=com_content&task=view&id=59&Itemid=103/)
person:Jennifer Fostel
web-page:http://www.pkware.com/index.php?option=com_content&task=view&id=59&Itemid=103/
zip
tar
Example.tar file.
tar is a format standard of a digital entity that is conformant with the tape archive file format as standardized by POSIX.1-1998, POSIX.1-2001, or any other tar format compliant with the GNU tar specification. (http://www.gnu.org/software/tar/manual/)
person:Jennifer Fostel
web-page:http://www.gnu.org/software/tar/manual/
tar
FCS
d01.fcs, FCS3 data file of well D06 of plate 2 of part 1 of a GvHD experiment.
FCS is a format standard of a digital entity that is conformant with the Flow Cytometry Data File Standard.(http://www.fcspress.com/)
person:Jennifer Fostel
web-page:http://www.fcspress.com/
FCS
Compensation-ML
compfoo.xml, Compensation-ML file describing compensation used in a GvHD experiment
Compensation-ML is a format standard of a digital entity that is conformant with the Compensation-ML standard. (http://wiki.ficcs.org/ficcs/Compensation-ML?action=AttachFile&do=get&target=Compensation-ML_v1.0.24.pdf)
person:Jennifer Fostel
web-page:http://wiki.ficcs.org/ficcs/Compensation-ML?action=AttachFile&do=get&target=Compensation-ML_v1.0.24.pdf
Compensation-ML
Gating-ML
foogate.xml, Gating-ML file describing gates used in a GvHD experiment.
Gating-ML is a format standard of a digital entity that is conformant with the Gating-ML standard. (http://www.flowcyt.org/gating/)
person:Jennifer Fostel
web-page:http://www.flowcyt.org/gating/
Gating-ML
OWL
OBI ontology file, Basic Formal Ontology file, BIRNLex file, BioPAX file.
OWL is a format standard of a digital entity that is conformant with the W3C Web Ontology Language specification.(http://www.w3.org/2004/OWL/)
person:Jennifer Fostel
web-page:http://www.w3.org/2004/OWL/
OWL
Affymetrix
Affymetrix supplied microarray
An organization which supplies technology, tools and protocols for use in high throughput applications
Affymetrix
Thermo
Philippe Rocca-Serra
Thermo
Waters
Philippe Rocca-Serra
Waters
BIO-RAD
Philippe Rocca-Serra
BIO-RAD
GenePattern hierarchical clustering
James Malone
GenePattern hierarchical clustering
Ambion
Philippe Rocca-Serra
Ambion
Helicos
Philippe Rocca-Serra
Helicos
Roche
Philippe Rocca-Serra
Roche
Illumina
Philippe Rocca-Serra
Illumina
GenePattern PCA
GenePattern PCA
GenePattern module SVM
GenePattern module SVM is a GenePattern software module which is used to run a support vector machine data transformation.
James Malone
Ryan Brinkman
GenePattern module SVM
GenePattern k-nearest neighbors
James Malone
GenePattern k-nearest neighbors
GenePattern LOOCV
GenePattern LOOCV
GenePattern k-means clustering
James Malone
GenePattern k-means clustering
Agilent
Philippe Rocca-Serra
Agilent
GenePattern module KMeansClustering
GenePattern module KMeansClustering is a GenePattern software module which is used to perform a k Means clustering data transformation.
James Malone
PERSON: James Malone
GenePattern module KMeansClustering
GenePattern CART
James Malone
GenePattern CART
GenePattern module CARTXValidation
GenePattern module CARTXValidation is a GenePattern software module which uses a CART decision tree induction with a leave one out cross validation data transformations.
GenePattern module CARTXValidation
Li-Cor
Philippe Rocca-Serra
Li-Cor
Bruker Corporation
Philippe Rocca-Serra
Bruker Corporation
GenePattern module KNNXValidation
GenePattern module KNNXValidation is a GenePattern software module which uses a k-nearest neighbours clustering with a leave one out cross validation data transformations.
James Malone
PERSON: James Malone
GenePattern module KNNXValidation
GenePattern module PeakMatch
GenePattern module PeakMatch
GenePattern module KNN
GenePattern module KNN is a GenePattern software module which perform a k-nearest neighbors data transformation.
James Malone
GenePattern module KNN
GenePattern module HierarchicalClustering
GenePattern module HierarchicalClustering is a GenePattern software module which is used to perform a hierarchical clustering data transformation.
James Malone
PERSON: James Malone
GenePattern module HierarchicalClustering
GenePattern SVM
James Malone
GenePattern SVM
Applied Biosystems
Philippe Rocca-Serra
Applied Biosystems
GenePattern module PCA
GenePattern module PCA is a GenePattern software module which is used to perform a principal components analysis dimensionality reduction data transformation.
James Malone
PERSON: James Malone
GenePattern module PCA
GenePattern peak matching
James Malone
Ryan Brinkman
GenePattern peak matching
Bruker Daltonics
Philippe Rocca-Serra
Bruker Daltonics
GenePattern HeatMapViewer data visualization
The GenePattern process of generating Heat Maps from clustered data.
James Malone
GenePattern HeatMapViewer data visualization
GenePattern HierarchicalClusteringViewer data visualization
The GenePattern process of generating hierarchical clustering visualization from clustered data.
James Malone
GenePattern HierarchicalClusteringViewer data visualization
GenePattern module HeatMapViewer
A GenePattern software module which is used to generate a heatmap view of data.
James Malone
GenePattern module HeatMapViewer
GenePattern module HierarchicalClusteringViewer
A GenePattern software module which is used to generate a view of data that has been hierarchically clustered.
James Malone
GenePattern module HierarchicalClusteringViewer
Sysmex Corporation, Kobe, Japan
WEB:http://www.sysmex.com/@2009/08/06
Sysmex Corporation, Kobe, Japan
U.S. Food and Drug Administration
FDA
U.S. Food and Drug Administration
right handed
right handed
ambidexterous
ambidexterous
left handed
left handed
Edingburgh handedness inventory
The Edinburgh Handedness Inventory is a set of questions used to assess the dominance of a person's right or left hand in everyday activities.
PERSON:Alan Ruttenberg
PERSON:Jessica Turner
PMID:5146491#Oldfield, R.C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia, 9, 97-113
WEB:http://www.cse.yorku.ca/course_archive/2006-07/W/4441/EdinburghInventory.html
Edingburgh handedness inventory
eBioscience
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.ebioscience.com/@2011/04/11
eBioscience
Cytopeia
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.cytopeia.com/@2011/04/11
Cytopeia
Exalpha Biological
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.exalpha.com/@2011/04/11
Exalpha Biological
Apogee Flow Systems
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.apogeeflow.com/@2011/04/11
Apogee Flow Systems
Exbio Antibodies
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.exbio.cz/@2011/04/11
Exbio Antibodies
Becton Dickinson (BD Biosciences)
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.bdbiosciences.com/@2011/04/11
Becton Dickinson (BD Biosciences)
Dako Cytomation
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.dakousa.com/@2011/04/11
Dako Cytomation
Millipore
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.guavatechnologies.com/@2011/04/11
Millipore
Antigenix
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.antigenix.com/@2011/04/11
Antigenix
Partec
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.partec.de/@2011/04/11
Partec
Beckman Coulter
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.beckmancoulter.com/@2011/04/11
Beckman Coulter
Advanced Instruments Inc. (AI Companies)
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.aicompanies.com/@2011/04/11
Advanced Instruments Inc. (AI Companies)
Miltenyi Biotec
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.miltenyibiotec.com/@2011/04/11
Miltenyi Biotec
AES Chemunex
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.aeschemunex.com/@2011/04/11
AES Chemunex
Bentley Instruments
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://bentleyinstruments.com/@2011/04/11
Bentley Instruments
Invitrogen
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.invitrogen.com/@2011/04/11
Invitrogen
Luminex
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.luminexcorp.com/@2011/04/11
Luminex
CytoBuoy
A supplier of flow cytometry analyzers
Karin Breuer
WEB:http://www.cytobuoy.com/@2011/04/11
CytoBuoy
Nimblegen
An organization that focuses on manufacturing target enrichment probe pools for DNA sequencing.
Person: Jie Zheng
Nimblegen
Pacific Biosciences
An organization that supplies tools for studying the synthesis and regulation of DNA, RNA and protein. It developed a powerful technology platform called single molecule real-time (SMRT) technology which enables real-time analysis of biomolecules with single molecule resolution.
Person: Jie Zheng
Pacific Biosciences
NanoString Technologies
An organization that supplies life science tools for translational research and molecular diagnostics based on a novel digital molecular barcoding technology. The NanoString platform can provide simple, multiplexed digital profiling of single molecules.
NanoString Technologies
Thermo Fisher Scientific
An organization that is an American multinational, biotechnology product development company, created in 2006 by the merger of Thermo Electron and Fisher Scientific.
Chris Stoeckert, Helena Ellis
https://en.wikipedia.org/wiki/Thermo_Fisher_Scientific
Thermo Fisher Scientific
A histologic grade according to AJCC 7th edition indicating that the tumor cells and the organization of the tumor tissue appear close to normal.
Chris Stoeckert, Helena Ellis
G1
https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet
NCI BBRB
G1: Well differentiated
A histologic grade according to AJCC 7th edition indicating that the tumor cells are moderately differentiated and reflect an intermediate grade.
Chris Stoeckert, Helena Ellis
G2
https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet
NCI BBRB
G2: Moderately differentiated
A histologic grade according to AJCC 7th edition indicating that the tumor cells are poorly differentiated and do not look like normal cells and tissue.
Chris Stoeckert, Helena Ellis
G3
https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet
NCI BBRB
G3: Poorly differentiated
A histologic grade according to AJCC 7th edition indicating that the tumor cells are undifferentiated and do not look like normal cells and tissue.
Chris Stoeckert, Helena Ellis
G4
https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet
NCI BBRB
G4: Undifferentiated
A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are round, uniform, approximately 10um and that nucleoli are inconspicuous or absent.
Chris Stoeckert, Helena Ellis
Grade 1
NCI BBRB, OBI
NCI BBRB
G1 (Fuhrman)
A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are slightly irregular, approximately 15um and nucleoli are evident.
Chris Stoeckert, Helena Ellis
Grade 2
NCI BBRB, OBI
NCI BBRB
G2 (Fuhrman)
A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are very irregular, approximately 20um and nucleoli large and prominent.
Chris Stoeckert, Helena Ellis
Grade 3
NCI BBRB, OBI
NCI BBRB
G3 (Fuhrman)
A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei arei bizarre and multilobulated, 20um or greater and nucleoli are prominent and chromatin clumped.
Chris Stoeckert, Helena Ellis
Grade 4
NCI BBRB, OBI
NCI BBRB
G4 (Fuhrman)
A histologic grade for ovarian tumor according to a two-tier grading system indicating that the tumor is low grade.
Chris Stoeckert, Helena Ellis
Low grade
NCI BBRB, OBI
NCI BBRB
Low grade ovarian tumor
A histologic grade for ovarian tumor according to a two-tier grading system indicating that the tumor is high grade.
Chris Stoeckert, Helena Ellis
High grade
NCI BBRB, OBI
NCI BBRB
High grade ovarian tumor
A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is well differentiated.
Chris Stoeckert, Helena Ellis
G1
NCI BBRB, OBI
NCI BBRB
G1 (WHO)
A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is moderately differentiated.
Chris Stoeckert, Helena Ellis
G2
NCI BBRB, OBI
NCI BBRB
G2 (WHO)
A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is poorly differentiated.
Chris Stoeckert, Helena Ellis
G3
NCI BBRB, OBI
NCI BBRB
G3 (WHO)
A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is undifferentiated.
Chris Stoeckert, Helena Ellis
G4
NCI BBRB, OBI
NCI BBRB
G4 (WHO)
A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that there is no evidence of primary tumor.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/
NCI BBRB
pT0 (colon)
A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating carcinoma in situ (intraepithelial or invasion of lamina propria).
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/
NCI BBRB
pTis (colon)
A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades submucosa.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/
NCI BBRB
pT1 (colon)
A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades muscularis propria.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/
NCI BBRB
pT2 (colon)
A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades subserosa or into non-peritionealized pericolic or perirectal tissues.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/
NCI BBRB
pT3 (colon)
A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor perforates visceral peritoneum.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/
NCI BBRB
pT4a (colon)
A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor directly invades other organs or structures.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/
NCI BBRB
pT4b (colon)
A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that there is no evidence of primary tumor.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/
NCI BBRB
pT0 (lung)
A pathologic primary tumor stage for lung according to AJCC 7th edition indicating carcinoma in situ.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/
NCI BBRB
pTis (lung)
A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is 3 cm or less in greatest dimension, surrounded by lung or visceral pleura without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus).
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/
NCI BBRB
pT1 (lung)
A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is 2 cm or less in greatest dimension.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/
NCI BBRB
pT1a (lung)
A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 2 cm but not more than 3 cm in greatest dimension.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/
NCI BBRB
pT1b (lung)
A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 3 cm but not more than 7 cm or the tumor has any of the following features: involves main bronchus, 2 cm or more distal to the carina, invades visceral pleura, associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/
NCI BBRB
pT2 (lung)
A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 3 cm but not more than 5 cm in greatest dimension.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/
NCI BBRB
pT2a (lung)
A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 5 cm but not more than 7 cm in greatest dimension.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/
NCI BBRB
pT2b (lung)
A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 7 cm or one that directly invades any of: parietal pleura, chest wall (including superior sulcus tumors), diaphragm, phrenic nerve, mediastinal pleura, parietal pericardiu or the tumor is in the main bronchus less than 2 cm distal to the carina but without involvement of the carina or there is associated atelectasis or obstructive pneumonitis of the entire lung or there is separate tumor nodule(s) in the same lobe as the primary.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/
NCI BBRB
pT3 (lung)
A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor of any size that invades any of the following: mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina or there is separate tumor nodule(s) in a different ipsilateral lobe to that of the primary.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/
NCI BBRB
pT4 (lung)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that there is no evidence of primary tumor.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT0 (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is 7 cm or less in greatest dimension and limited to the kidney.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT1 (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is 4 cm or less.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT1a (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 4 cm but not more than 7 cm.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT1b (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 7 cm in greatest dimension and limited to the kidney.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT2 (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 7 cm but not more than 10 cm.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT2a (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 10 cm and limited to the kidney.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT2b (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor extends into major veins or perinephric tissues but not into the ipsilateral adrenal gland and not beyond the Gerota fascia.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT3 (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into the renal vein or its segmental (muscle containing) branches, or the tumor invades perirenal and/or renal sinus fat (peripelvic) fat but not beyond Gerota fascia.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT3a (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into vena cava below diaphragm.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT3b (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into vena cava above the diaphragm or Invades the wall of the vena cava.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT3c (kidney)
A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor invades beyond Gerota fascia (including contiguous extension into the ipsilateral adrenal gland).
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/
NCI BBRB
pT4 (kidney)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that there is no evidence of primary tumor.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT0 (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to the ovaries (one or both).
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT1 (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to one ovary; capsule intact, no tumor on ovarian surface and no malignant cells in ascites or peritoneal washings.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT1a (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to both ovaries; capsule intact, no tumor on ovarian surface and no malignant cells in ascites or peritoneal washings.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT1b (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to one or both ovaries with capsule ruptured, tumor on ovarian surface, or malignant cells in ascites or peritoneal washings.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT1c (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor involves one or both ovaries with pelvic extension.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT2 (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has extension and/or implants on uterus and/or tube(s) and no malignant cells in ascites or peritoneal washings.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT2a (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has extension to other pelvic tissues and no malignant cells in ascites or peritoneal washings.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT2b (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has pelvic extension with malignant cells in ascites or peritoneal washings.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT2c (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor involves one or both ovaries with microscopically confirmed peritoneal metastasis outside the pelvis and/or regional lymph node metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT3 (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has microscopic peritoneal metastasis beyond pelvis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT3a (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has macroscopic peritoneal, metastatasis beyond pelvis, 2 cm or less in greatest dimension.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT3b (ovary)
A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has peritoneal metastasis beyond pelvis, more than 2 cm in greatest dimension and/or regional lymph node metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/
NCI BBRB
pT3c (ovary)
A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating no regional lymph node metastsis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/
NCI BBRB
pN0 (colon)
A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 1-3 regional lymph nodes.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/
NCI BBRB
pN1 (colon)
A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 1 regional lymph node.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/
NCI BBRB
pN1a (colon)
A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 2-3 regional lymph nodes.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/
NCI BBRB
pN1b (colon)
A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating tumor deposit(s), i.e., satellites in the subserosa, or in non-peritonealized pericolic or perirectal soft tissue without regional lymph node metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/
NCI BBRB
pN1c (colon)
A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 4 or more regional lymph nodes.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/
NCI BBRB
pN2 (colon)
A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 4 to 6 regional lymph nodes.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/
NCI BBRB
pN2a (colon)
A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 7 or more regional lymph nodes.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/
NCI BBRB
pN2b (colon)
A pathologic lymph node stage for lung according to AJCC 7th edition indicating no regional lymph node metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/
NCI BBRB
pN0 (lung)
A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/
NCI BBRB
pN1 (lung)
A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s).
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/
NCI BBRB
pN2 (lung)
A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s).
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/
NCI BBRB
pN3 (lung)
A pathologic lymph node stage for kidney according to AJCC 7th edition indicating that there is no regional lymph node metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_n/
NCI BBRB
pN0 (kidney)
A pathologic lymph node stage for kidney according to AJCC 7th edition indicating that there is regional lymph node metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_n/
NCI BBRB
pN1 (kidney)
A pathologic lymph node stage for ovary according to AJCC 7th edition indicating that there is no regional lymph node metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_n/
NCI BBRB
pN0 (ovary)
A pathologic lymph node stage for ovary according to AJCC 7th edition indicating that there is regional lymph node metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_n/
NCI BBRB
pN1 (ovary)
A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there are no symptoms or signs of distant metastasis.
Chris Stoeckert, Helena Ellis
https://en.wikipedia.org/wiki/Cancer_staging#Pathological_M_Categorization_.28cM_and_pM.29
NCI BBRB
cM0 (colon)
A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there is clinical evidence of distant metastases by history, physical examination, imaging studies, or invasive procedures, but without microscopic evidence of the presumed distant metastases.
Chris Stoeckert, Helena Ellis
https://en.wikipedia.org/wiki/Cancer_staging#Pathological_M_Categorization_.28cM_and_pM.29
NCI BBRB
cM1 (colon)
A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is confined to one organ based on clinical assessment.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/
NCI BBRB
cM1a (colon)
A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is in more than one organ or the peritoneum based on clinical assessment.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/
NCI BBRB
cM1b (colon)
A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there is microscopic evidence confirming distant metastatic disease.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/
NCI BBRB
pM1 (colon)
A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is confined to one organ and histologically confirmed.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/
NCI BBRB
pM1a (colon)
A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is in more than one organ or the peritoneum and histologically confirmed.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/
NCI BBRB
pM1b (colon)
A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is no distant metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/
NCI BBRB
cM0 (lung)
A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there are distant metastases based on clinical assessment.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/
NCI BBRB
cM1 (lung)
A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that metastasis is based on clinical assessment and a separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules OR malignant pleural or pericardial effusion.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/
NCI BBRB
cM1a (lung)
A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases based on clinical assessment.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/
NCI BBRB
cM1b (lung)
A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/
NCI BBRB
pM1 (lung)
A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that metastasis is histologically confirmed and a separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules OR malignant pleural or pericardial effusion.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/
NCI BBRB
pM1a (lung)
A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed and associated with distant lymph nodes or carcinomatosis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/
NCI BBRB
pM1b (lung)
A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there is no distant metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_m/
NCI BBRB
cM0 (kidney)
A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there are distant metastases based on clinical assessment.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_m/
NCI BBRB
cM1 (kidney)
A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_m/
NCI BBRB
pM1 (kidney)
A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is no distant metastasis.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_m/
NCI BBRB
cM0 (ovary)
A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is distant metastasis except peritoneal metastasis based on clinical assessment.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_m/
NCI BBRB
cM1 (ovary)
A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is distant metastasis except peritoneal metastasis that is histologically confirmed.
Chris Stoeckert, Helena Ellis
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_m/
NCI BBRB
pM1 (ovary)
A clinical tumor stage group according to AJCC 7th edition indicating a small carcinoma, either asymptomatic or giving rise to metastases without symptoms due to the primary carcinoma.
Chris Stoeckert, Helena Ellis
Occult Carcinoma
http://www.medilexicon.com/dictionary/14371
NCI BBRB
Occult Carcinoma (AJCC 7th)
A clinical tumor stage group according to AJCC 7th edition indicating a carcinoma in situ (or melanoma in situ for melanoma of the skin or germ cell neoplasia in situ for testicular germ cell tumors) and generally is considered to have no metastatic potential.
Chris Stoeckert, Helena Ellis
Stage 0
https://en.wikipedia.org/wiki/Cancer_staging
NCI BBRB
Stage 0 (AJCC 7th)
A clinical tumor stage group according to AJCC 7th edition indicating cancers that are smaller or less deeply invasive without regional disease or nodes.
Chris Stoeckert, Helena Ellis
Stage I
https://en.wikipedia.org/wiki/Cancer_staging
NCI BBRB
Stage I (AJCC 7th)
A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIB and IIC.
Chris Stoeckert, Helena Ellis
Stage IIA
https://en.wikipedia.org/wiki/Cancer_staging
NCI BBRB
Stage IIA (AJCC 7th)
A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIA and IIC.
Chris Stoeckert, Helena Ellis
Stage IIB
https://en.wikipedia.org/wiki/Cancer_staging
NCI BBRB
Stage IIB (AJCC 7th)
A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIA and IIB.
Chris Stoeckert, Helena Ellis
Stage IIC
https://en.wikipedia.org/wiki/Cancer_staging
NCI BBRB
Stage IIC (AJCC 7th)
A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIB and IIIC.
Chris Stoeckert, Helena Ellis
Stage IIIA
https://en.wikipedia.org/wiki/Cancer_staging
NCI BBRB
Stage IIIA (AJCC 7th)
A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIA and IIIC.
Chris Stoeckert, Helena Ellis
Stage IIIB
https://en.wikipedia.org/wiki/Cancer_staging
NCI BBRB
Stage IIIB (AJCC 7th)
A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIA and IIIB.
Chris Stoeckert, Helena Ellis
Stage IIIC
https://en.wikipedia.org/wiki/Cancer_staging
NCI BBRB
Stage IIIC (AJCC 7th)
A clinical tumor stage group according to AJCC 7th edition indicating cancers in patients who present with distant metastases at diagnosis and with differing characteristics from IVB.
Chris Stoeckert, Helena Ellis
Stage IVA
https://en.wikipedia.org/wiki/Cancer_staging
NCI BBRB
Stage IVA (AJCC 7th)
A clinical tumor stage group according to AJCC 7th edition indicating cancers in patients who present with distant metastases at diagnosis and with differing characteristics from IVA.
Chris Stoeckert, Helena Ellis
Stage IVB
https://en.wikipedia.org/wiki/Cancer_staging
NCI BBRB
Stage IVB (AJCC 7th)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating invasive carcinoma which can be diagnosed only by microscopy, with deepest invasion <5 mm and the largest extension <7 mm.
Chris Stoeckert, Helena Ellis
Stage IA
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IA (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating measured stromal invasion of <3.0 mm in depth and extension of <7.0 mm.
Chris Stoeckert, Helena Ellis
Stage IA1
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IA1 (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating measured stromal invasion of >3.0 mm and not >5.0 mm with an extension of not >7.0 mm.
Chris Stoeckert, Helena Ellis
Stage IA2
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IA2 (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesions limited to the cervix uteri or pre-clinical cancers greater than stage IA
Chris Stoeckert, Helena Ellis
Stage IB
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IB (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesion limited to the cervix uteri or pre-clinical cancers greater than stage IA <4.0 cm in greatest dimension.
Chris Stoeckert, Helena Ellis
Stage IB1
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IB1 (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesion limited to the cervix uteri or pre-clinical cancers greater than stage IA >4.0 cm in greatest dimension.
Chris Stoeckert, Helena Ellis
Stage IB2
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IB2 (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion.
Chris Stoeckert, Helena Ellis
Stage IIA
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IIA (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion and clinically visible lesion <4.0 cm in greatest dimension.
Chris Stoeckert, Helena Ellis
Stage IIA1
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IIA1 (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion and clinically visible lesion >4.0 cm in greatest dimension.
Chris Stoeckert, Helena Ellis
Stage IIA2
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IIA2 (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina with obvious parametrial invasion.
Chris Stoeckert, Helena Ellis
Stage IIB
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IIB (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating tumour involves lower third of the vagina, with no extension to the pelvic wall.
Chris Stoeckert, Helena Ellis
Stage IIIA
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IIIA (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating extension to the pelvic wall and/or hydronephrosis or non-functioning kidney.
Chris Stoeckert, Helena Ellis
Stage IIIB
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IIIB (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating spread of the growth to adjacent organs.
Chris Stoeckert, Helena Ellis
Stage IVA
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IVA (FIGO)
An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating spread to distant organs.
Chris Stoeckert, Helena Ellis
Stage IVB
https://en.wikipedia.org/wiki/Cervical_cancer_staging
NCI BBRB
Stage IVB (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1, N0, and M0.
Chris Stoeckert, Helena Ellis
Stage 1
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 1 (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1a, N0, and M0.
Chris Stoeckert, Helena Ellis
Stage 1A
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 1A (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1b, N0, and M0.
Chris Stoeckert, Helena Ellis
Stage 1B
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 1B (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1c, N0, and M0.
Chris Stoeckert, Helena Ellis
Stage 1C
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 1C (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2, N0, and M0.
Chris Stoeckert, Helena Ellis
Stage 2
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 2 (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2a, N0, and M0.
Chris Stoeckert, Helena Ellis
Stage 2A
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 2A (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2b, N0, and M0.
Chris Stoeckert, Helena Ellis
Stage 2B
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 2B (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2c, N0, and M0.
Chris Stoeckert, Helena Ellis
Stage 2C
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 2C (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T3, N0, and M0) or (T3,3a,3b, NX, and M0).
Chris Stoeckert, Helena Ellis
Stage 3
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 3 (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T3a, N0, and M0 .
Chris Stoeckert, Helena Ellis
Stage 3A
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 3A (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T3b, N0, and M0 .
Chris Stoeckert, Helena Ellis
Stage 3B
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 3B (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T3c, N0,X and M0) or (any T, N1 and M0).
Chris Stoeckert, Helena Ellis
Stage 3C
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 3C (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of any T, any N, and M1.
Chris Stoeckert, Helena Ellis
Stage 4
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage 4 (FIGO)
A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T0, N0, and M0) or (T1,1a-1c,2,2a-2c, NX, and M0) or (TX, N0,X, M0).
Chris Stoeckert, Helena Ellis
Stage Unknown
https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/
NCI BBRB
Stage Unknown (FIGO)
An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic and in bed for more than 50% of the day but is not bed ridden.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
3: symptomatic in bed more than 50% of the day but not bed ridden
An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic but is in bed for less than 50% of the day.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
2: symptomatic but in bed less than 50% of the day
An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic and is bed ridden.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
4: bed ridden
An Eastern Cooperative Oncology Group score value specification indicating a patient is asymptomatic.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
0: asymptomatic
An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic but is fully ambulatory.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
1: symptomatic but fully ambulatory
A Karnofsky score vaue specification indicating that a patient is asymptomatic.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
100: asymptomatic
A Karnofsky score vaue specification indicating that a patient is symptomatic but fully ambulatory.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
80-90: symptomatic but fully ambulatory
A Karnofsky score vaue specification indicating that a patient is symptomatic but in bed less than 50% of the day.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
60-70: symptomatic but in bed less than 50% of the day
A Karnofsky score vaue specification indicating that a patient is symptomatic, in bed more than 50% of the day, but not bed ridden.
Chris Stoeckert, Helena Ellis
NCI BBRB, OBI
NCI BBRB
40-50: symptomatic, in bed more than 50% of the day, but not bed ridden
Oxford Nanopore Technologies
An organization that is developing and selling nanopore sequencing products and is based in the UK.
James A. Overton
https://en.wikipedia.org/wiki/Oxford_Nanopore_Technologies
Oxford Nanopore Technologies
"An area unit which is equal to an area enclosed by a square with sides each 1 meter long." [NIST:NIST]
square meter
third planet from the Sun in the Solar System
Earth
third planet from the Sun in the Solar System
https://www.wikidata.org/wiki/Q2
"Suni, or Jalca, is one of the eight Natural Regions of Peru. It is located in the Andes at an altitude between 3,500 and 4,000 metres above sea level. Suni has a dry and cold weather and there are many glacial valleys. The flora includes gramineous plants and shrubs such as the taya-taya (Caesalpinia spinosa), the quishuar (Buddleja coriacea), and the cantuta (Cantua buxifolia) which was considered sacred by the Incas. Even though it is hard for plants to grow because of the weather, people are able to cultivate such crops as quinoa, qañiwa, broad beans and ulluku (Ullucus tuberosus). The main fauna is the guinea pig and, among numerous other highland birds, the Chiguanco thrush."
Jalca
Suni
"Suni, or Jalca, is one of the eight Natural Regions of Peru. It is located in the Andes at an altitude between 3,500 and 4,000 metres above sea level. Suni has a dry and cold weather and there are many glacial valleys. The flora includes gramineous plants and shrubs such as the taya-taya (Caesalpinia spinosa), the quishuar (Buddleja coriacea), and the cantuta (Cantua buxifolia) which was considered sacred by the Incas. Even though it is hard for plants to grow because of the weather, people are able to cultivate such crops as quinoa, qañiwa, broad beans and ulluku (Ullucus tuberosus). The main fauna is the guinea pig and, among numerous other highland birds, the Chiguanco thrush."
https://en.wikipedia.org/wiki/Suni_(geography)
Earth's interconnected water system
World Ocean
Earth's interconnected water system
https://www.wikidata.org/wiki/Q715269